Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838547-134902034 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 44.8;liver: 64.1" "Cell type enhanced" "Detected in some" 29 "Cholangiocytes: 58.6;Distal tubular cells: 46.4;Hepatocytes: 104.7;Proximal tubular cells: 312.9" "Group enriched" "Detected in some" 23 "liver cancer: 21.2;renal cancer: 19.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 24.8" "Not detected" "Not detected" "HPA010533, HPA011179" Enhanced NA NA 11000 "HPA010533: AB_1844517, HPA011179: AB_1844516" "unprognostic (1.06e-2)" "unprognostic (5.30e-2)" "unprognostic (1.40e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-4)" "unprognostic (7.60e-2)" "unprognostic (5.17e-2)" "unprognostic (2.44e-3)" "prognostic favorable (2.39e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.65e-5)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 2.5 0.0 0.0 0.0 44.8 64.1 0.1 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 1.4 0.9 0.6 0.2 1.7 0.5 0.3 0.1 0.4 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.2 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.4 0.0 0.0 0.3 0.6 0.2 1.1 0.1 0.5 0.1 0.5 0.2 24.8 0.3 1.0 0.3 0.1 0.2 0.4 0.7 0.2 0.6 0.8 0.0 0.3 0.2 0.7 0.2 0.1 0.4 0.2 0.3 0.6 0.0 0.6 0.9 0.9 0.5 0.4 1.5 0.9 1.3 0.9 1.1 1.7 0.9 0.4 0.2 0.5 1.4 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.1 58.6 0.0 0.0 8.7 0.0 0.0 46.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.7 0.0 0.0 0.0 2.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 312.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.9" "Cell type enhanced" "Detected in many" 8 "Hepatocytes: 174.5;Proximal tubular cells: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 53.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 8000000 "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 41.4 27.2 9.6 7.1 9.4 1.5 30.1 8.9 8.1 9.3 19.7 6.2 6.4 21.9 12.8 14.6 12.8 7.2 8.9 15.1 6.5 7.6 40.5 80.9 9.2 9.4 6.1 6.2 14.1 27.9 8.9 8.7 11.3 7.7 10.7 9.8 11.7 11.7 9.5 11.2 5.5 28.4 14.5 6.0 6.4 13.5 11.4 5.9 6.0 18.4 7.2 5.1 13.9 11.7 4.7 7.1 21.4 8.8 4.7 7.4 6.2 9.5 8.7 6.8 10.7 53.1 28.8 3.1 18.1 44.5 8.3 6.6 9.2 3.0 1.9 5.8 18.9 22.8 1.3 13.5 17.3 16.8 6.0 3.6 14.0 9.5 10.0 26.7 1.3 5.6 25.0 5.3 21.4 15.1 25.7 21.5 7.4 5.0 4.1 23.7 2.5 7.4 6.7 7.1 6.0 9.4 5.8 10.1 1.9 31.7 8.8 0.9 2.8 18.8 0.7 1.9 7.6 4.4 3.4 23.2 30.4 10.3 10.1 4.7 2.1 3.9 3.8 21.2 4.7 2.6 21.4 8.7 2.4 7.4 8.8 6.4 4.7 5.2 5.7 7.1 4.2 6.8 7.0 1.0 4.7 7.2 3.4 2.8 6.2 9.6 9.4 8.9 8.1 6.5 7.6 6.1 6.2 7.7 5.9 3.0 25.5 7.5 6.9 3.9 18.8 39.8 45.9 8.1 9.1 22.7 21.6 39.8 16.6 14.3 6.3 18.2 29.7 0.0 35.8 17.8 21.6 11.2 2.3 174.5 13.3 31.8 4.7 14.1 12.7 5.1 21.9 7.2 6.8 2.8 32.4 30.7 23.2 21.0 21.9 160.8 13.9 19.4 22.3 6.1 16.2 4.6 44.7 8.7 26.9 7.1 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41469125-41528989 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 121.0;skeletal muscle: 157.9" "Cell type enhanced" "Detected in all" 5 "Proximal tubular cells: 244.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 4000000 Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 22.8 18.5 41.4 11.1 38.2 9.8 12.2 21.0 43.5 12.2 25.4 27.7 12.3 45.1 9.5 9.9 17.5 15.7 11.1 121.0 33.8 24.2 37.9 22.2 10.0 11.1 27.6 32.7 8.6 17.2 48.5 7.6 9.1 24.9 12.5 20.0 14.7 20.1 15.2 157.9 9.8 46.6 12.5 28.6 10.0 21.0 9.6 23.1 9.5 16.0 42.7 12.0 12.3 8.8 22.9 28.1 7.3 36.6 15.8 16.4 19.4 13.9 16.2 16.3 33.7 28.2 18.4 22.9 12.8 16.3 21.6 20.2 23.9 18.2 32.0 21.0 19.1 18.1 32.1 30.3 23.5 11.4 21.2 21.6 15.5 22.7 25.4 24.6 41.3 23.8 32.6 18.9 22.4 23.9 16.7 21.4 17.1 20.0 35.0 17.0 26.1 21.1 14.0 11.1 79.8 32.6 28.6 11.2 44.4 27.9 27.7 11.7 10.0 31.6 37.3 23.8 14.0 21.7 22.1 15.2 18.5 20.7 16.8 14.0 20.8 25.8 22.4 29.9 18.1 19.9 4.5 21.1 7.3 14.7 31.3 14.0 22.9 12.5 15.8 28.1 20.2 14.2 14.6 5.3 15.8 36.6 11.2 16.4 19.4 41.4 38.2 21.0 43.5 33.8 24.2 27.6 32.7 24.9 23.1 23.8 35.1 48.4 42.0 16.7 52.7 8.1 53.5 38.8 18.2 57.6 76.6 84.6 111.0 47.3 10.7 21.1 193.9 23.3 37.3 50.2 22.9 31.1 40.3 50.4 81.0 50.9 51.1 16.5 27.5 6.8 22.5 35.7 33.7 87.4 92.9 56.0 39.9 87.7 26.2 244.6 62.4 58.2 31.1 23.6 36.4 14.1 161.6 34.6 88.8 55.9 ACOD1 "CAD, IRG1" ENSG00000102794 "Aconitate decarboxylase 1" A6NK06 13 76948497-76958642 "Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 3.0;lymphoid tissue: 5.8" "Cell type enriched" "Detected in single" 9 "Distal tubular cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "PC-3: 1.1;U-87 MG: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040143 Uncertain NA NA "HPA040143: AB_10793916" "unprognostic (2.39e-1)" "unprognostic (6.42e-2)" "unprognostic (2.37e-1)" "unprognostic (3.54e-2)" "unprognostic (3.09e-1)" "unprognostic (8.30e-2)" "unprognostic (4.30e-2)" "unprognostic (1.64e-5)" "unprognostic (7.70e-2)" "unprognostic (3.68e-2)" "unprognostic (6.51e-3)" 1.4 0.1 0.0 5.8 0.0 0.6 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.1 0.1 0.0 0.0 0.3 3.0 1.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.8 0.3 0.0 0.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.0" "Group enriched" "Detected in many" 8 "Cone photoreceptor cells: 490.9;Rod photoreceptor cells: 145.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 15.3;SH-SY5Y: 17.6;SK-MEL-30: 20.3;WM-115: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria NA NA Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 2.8 2.8 11.5 0.7 11.7 0.4 6.8 22.7 29.0 7.8 0.9 2.0 0.0 0.7 2.7 1.1 1.2 2.4 1.2 4.0 11.6 4.0 1.8 9.6 1.0 0.8 5.8 13.4 1.2 3.6 1.0 1.5 0.9 6.2 4.1 1.0 5.0 0.8 2.1 9.2 0.6 0.7 1.6 2.2 1.0 1.8 3.9 1.2 0.0 3.0 0.2 0.8 1.0 1.5 0.5 0.4 0.6 0.1 0.0 0.2 0.0 0.5 3.9 1.5 2.2 2.9 0.0 2.7 0.1 0.0 0.5 0.2 0.4 0.0 0.0 0.2 0.1 4.0 1.2 2.5 0.2 0.0 7.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 3.4 1.9 0.3 15.3 0.0 0.1 5.8 0.2 4.7 0.2 4.6 0.0 0.0 5.7 3.3 0.0 0.0 0.0 7.6 0.0 3.8 9.2 17.6 1.4 0.0 20.3 2.2 1.3 2.3 0.0 0.4 2.9 0.3 2.3 0.0 0.0 0.0 0.0 0.0 11.6 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 11.5 11.7 22.7 29.0 11.6 4.0 5.8 13.4 6.2 1.2 0.0 0.0 0.0 0.4 0.2 35.8 9.0 0.0 0.0 0.0 0.0 490.9 0.1 1.7 0.0 2.3 1.0 0.0 0.0 0.8 0.1 1.9 2.6 0.0 34.7 0.3 39.7 30.0 18.4 3.2 0.4 1.7 0.0 3.3 0.0 0.2 11.9 0.9 0.0 7.1 0.2 145.7 0.0 5.0 0.7 6.8 0.1 0.0 0.0 0.5 0.3 ADCY10 "HCA2, RP1-313L4.2, SAC, SACI, Sacy" ENSG00000143199 "Adenylate cyclase 10" Q96PN6 1 167809388-167914215 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "liver: 14.9;testis: 38.6" "Group enriched" "Detected in some" 11 "Early spermatids: 64.6;Late spermatids: 64.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.7" "Region enriched" "Detected in single" 5 "cerebellum: 1.6" "Cell type enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 2.7;T-47d: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015243, HPA017749" Approved NA NA "HPA015243: AB_1856540, HPA017749: AB_1856541" "unprognostic (1.20e-1)" "unprognostic (2.53e-1)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.05e-1)" "unprognostic (1.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.56e-1)" "unprognostic (1.63e-1)" "unprognostic (3.65e-1)" "unprognostic (4.43e-2)" "unprognostic (7.83e-5)" "unprognostic (5.86e-7)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "unprognostic (7.83e-2)" "unprognostic (2.59e-1)" 0.1 0.1 0.2 0.1 0.3 0.0 1.3 1.6 0.3 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.2 0.3 14.9 0.1 0.1 0.2 0.3 0.1 0.4 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.7 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 38.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.4 0.6 0.0 0.3 0.4 0.3 0.1 0.2 0.2 0.6 0.5 2.7 0.1 1.0 0.3 1.1 1.6 0.1 0.2 0.3 0.0 0.0 0.0 1.1 0.1 0.2 0.4 1.6 0.5 0.3 0.7 0.1 0.0 0.0 0.1 1.9 0.8 0.6 0.3 0.0 0.7 1.2 0.1 0.1 0.0 0.5 0.8 1.0 0.8 0.0 0.1 0.0 0.3 1.2 0.0 0.4 0.0 0.0 0.0 0.5 1.6 5.0 0.8 0.1 0.2 0.0 0.3 0.1 1.2 0.6 0.8 0.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.0 0.4 0.2 0.3 1.6 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 64.6 0.0 0.5 0.0 0.0 0.4 0.0 0.2 0.0 5.9 0.1 0.0 0.0 1.3 0.0 64.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 4.1 0.7 0.4 1.5 0.0 0.0 0.1 ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396208-7830081 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 35.9;skeletal muscle: 58.6" "Cell type enhanced" "Detected in many" 24 "Cone photoreceptor cells: 64.8;Horizontal cells: 190.7;Melanocytes: 38.8" "Cancer enhanced" "Detected in some" "glioma: 4.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "AF22: 9.0;NTERA-2: 6.9;SK-MEL-30: 7.5;SuSa: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved NA NA "CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799" "unprognostic (6.48e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-1)" "unprognostic (5.65e-2)" "unprognostic (3.77e-1)" "unprognostic (4.03e-4)" "unprognostic (1.94e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (7.68e-2)" "unprognostic (1.09e-5)" "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (4.90e-2)" "unprognostic (3.92e-3)" 1.8 3.3 16.8 1.3 14.5 1.2 2.8 6.6 35.9 4.9 1.9 6.7 0.7 1.9 3.9 1.7 4.0 4.1 2.1 1.2 14.5 9.4 1.2 1.1 1.3 1.1 12.8 10.0 5.1 1.9 1.0 5.1 1.8 11.3 6.2 1.6 2.0 1.5 5.1 58.6 6.3 1.8 4.3 12.5 1.2 2.6 3.6 5.4 0.0 1.1 5.1 1.2 1.9 2.1 0.9 0.4 1.5 0.4 0.3 0.6 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.5 6.4 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.4 0.1 0.4 0.2 0.4 0.5 0.3 0.3 0.1 0.9 0.4 0.6 1.5 0.3 0.3 0.4 0.2 0.0 16.8 14.5 6.6 22.5 14.5 9.4 12.8 10.0 11.3 5.4 3.0 2.4 0.0 0.6 5.3 28.6 1.6 0.0 9.4 4.5 0.0 64.8 0.6 0.0 0.5 2.5 1.4 0.0 0.0 0.4 0.2 2.8 7.3 1.1 0.0 0.2 190.7 12.1 0.6 0.0 2.1 4.0 2.6 38.8 0.0 0.1 1.9 2.0 0.3 1.8 0.2 4.0 0.0 1.0 1.2 0.7 4.1 0.7 0.0 0.2 0.8 ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24919839 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 14 "Leydig cells: 54.1;Sertoli cells: 109.9;Smooth muscle cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved NA NA "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" 35.8 8.2 14.4 11.7 26.0 13.2 41.2 15.0 21.7 22.5 15.1 16.5 6.5 7.6 23.3 15.6 17.4 21.4 18.2 18.2 13.7 13.1 9.5 4.6 15.3 13.7 29.6 14.1 29.5 7.7 15.4 16.2 58.6 16.3 15.1 11.7 11.3 8.7 24.9 7.9 14.8 12.3 25.1 12.4 11.7 9.8 11.3 18.2 4.3 14.4 13.9 12.8 13.5 24.2 7.2 11.0 3.2 1.8 1.1 3.1 1.2 28.4 19.6 6.3 10.7 32.4 25.8 12.4 14.3 21.0 12.5 11.5 15.8 9.8 9.9 3.2 20.9 15.6 20.8 15.6 19.5 8.7 22.6 20.7 16.2 21.5 2.0 24.6 9.2 10.2 21.6 16.5 12.4 18.9 8.0 11.4 8.7 8.1 17.4 7.2 20.4 8.9 2.2 6.9 13.8 8.6 15.8 33.3 20.6 5.4 17.0 10.4 7.6 17.9 21.3 12.3 5.4 5.4 7.7 10.9 21.8 15.7 12.6 21.5 18.1 42.2 38.8 7.1 14.6 13.6 3.2 1.8 0.0 0.6 1.8 0.3 6.4 1.4 0.5 11.0 7.2 0.7 0.6 0.0 1.1 0.4 10.1 3.1 1.2 14.4 26.0 15.0 21.7 13.7 13.1 29.6 14.1 16.3 18.2 0.0 2.6 2.9 3.6 9.7 1.3 1.4 0.0 0.0 1.2 1.8 0.0 0.7 0.0 0.9 0.2 5.0 4.0 0.0 0.0 1.6 17.7 2.9 18.4 0.2 12.4 0.0 1.2 6.7 3.2 1.9 54.1 5.1 6.8 5.4 3.5 1.5 0.7 3.5 27.6 0.1 1.7 109.9 59.0 0.3 2.2 10.3 1.0 6.1 8.8 3.1 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Endothelial cells: 57.3;Ito cells: 40.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "basophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 9.9;TIME: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005070, HPA048344" Approved NA NA "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 15.8 2.7 2.3 4.6 2.0 1.5 14.2 1.1 2.4 13.3 4.4 1.6 6.3 1.7 16.8 10.0 6.0 7.7 10.9 10.3 1.6 1.4 6.3 2.0 14.7 8.4 2.3 1.5 3.2 2.1 4.7 1.8 17.8 2.7 4.8 2.3 5.8 3.6 8.0 6.2 4.4 3.9 7.0 1.9 9.3 3.4 2.6 1.6 0.0 7.4 7.3 3.3 5.9 12.6 0.0 1.1 5.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.9 0.4 1.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.8 0.0 0.2 0.0 0.0 9.9 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 4.1 0.3 0.1 1.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 5.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 2.3 2.0 1.1 2.4 1.6 1.4 2.3 1.5 2.7 1.6 0.0 2.6 0.0 0.2 3.2 0.0 8.1 0.0 1.4 1.2 1.8 0.0 0.1 0.0 0.8 1.0 57.3 1.7 0.0 2.8 0.1 1.7 0.2 1.1 0.0 1.3 1.6 1.2 40.5 7.2 5.9 0.0 2.3 6.8 3.6 5.0 0.8 1.4 1.5 0.0 0.0 0.3 6.5 2.3 0.3 0.5 2.5 0.0 2.6 1.6 0.3 ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449758 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 69.9" "Cell type enhanced" "Detected in many" 10 "Cardiomyocytes: 56.0;Paneth cells: 59.6;Peritubular cells: 69.3;Sertoli cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 18.0;RPMI-8226: 3.1;RPTEC TERT1: 6.5" "Region enriched" "Detected in many" 5 "basal ganglia: 347.3" "Region enriched" "Detected in all" 6 "basal ganglia: 205.1" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" NA NA "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 13.3 3.0 12.5 3.7 32.0 0.6 9.3 2.6 14.4 4.5 11.7 10.4 3.1 4.2 6.2 4.4 13.8 5.3 7.3 69.9 10.4 8.3 5.3 2.4 2.6 2.0 15.0 8.6 10.1 5.7 1.1 7.7 4.8 9.7 13.8 4.6 4.6 3.1 16.3 2.2 1.1 4.8 13.5 8.8 4.7 9.6 5.9 16.0 0.0 1.0 0.2 2.6 9.5 8.5 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.7 1.6 0.1 0.1 0.1 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.4 0.2 2.7 0.5 0.8 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 18.0 0.0 0.0 1.0 0.0 0.1 0.0 0.4 3.1 6.5 0.6 2.2 2.0 0.0 0.6 0.1 2.2 0.0 0.1 0.0 0.1 1.5 0.1 0.3 0.2 0.7 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 12.5 32.0 2.6 14.4 10.4 8.3 15.0 8.6 9.7 16.0 0.0 0.0 0.0 0.1 0.2 16.5 56.0 2.5 0.0 0.0 7.0 0.0 1.1 0.0 11.5 0.7 0.4 0.5 0.0 6.3 3.1 2.3 0.1 0.0 0.0 0.2 0.0 0.0 2.5 0.0 1.1 19.0 0.0 0.0 1.8 0.3 0.8 0.6 59.6 69.3 0.7 1.5 64.7 12.2 0.7 5.6 0.6 10.4 0.0 1.2 0.0 ADCY6 AC6 ENSG00000174233 "Adenylate cyclase 6" O43306 12 48766194-48789037 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Paneth cells: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018365 Approved Approved "Golgi apparatus" NA NA "Golgi apparatus" "CAB018365: AB_2257941" "unprognostic (1.18e-2)" "unprognostic (2.20e-2)" "unprognostic (6.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (3.68e-2)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-3)" "unprognostic (5.10e-3)" "unprognostic (1.09e-1)" "unprognostic (3.09e-1)" "unprognostic (2.48e-2)" 25.9 9.6 14.1 12.4 7.5 0.8 19.7 15.0 17.0 9.8 15.2 5.5 16.2 12.3 13.2 12.8 6.2 9.5 17.6 37.5 9.9 8.3 11.3 5.6 8.5 4.7 5.6 11.0 14.6 17.4 15.8 9.1 9.5 8.9 11.1 12.6 11.8 19.9 12.0 7.3 10.2 13.9 9.1 4.7 2.9 13.5 4.0 5.5 0.6 11.1 6.8 3.8 7.8 14.9 1.8 0.4 1.4 0.4 0.5 0.4 0.5 5.9 11.6 13.4 8.4 14.1 7.1 14.5 7.4 7.4 9.0 6.3 20.6 20.2 0.0 16.9 6.4 3.6 4.8 3.9 4.9 3.2 0.0 6.0 5.5 15.8 3.7 8.1 0.0 4.5 9.0 6.1 7.5 2.8 16.5 8.1 0.3 0.7 2.0 6.6 10.3 0.0 0.2 4.6 9.1 5.5 1.9 5.1 3.3 10.1 18.7 2.0 8.3 7.6 30.4 6.6 5.9 23.7 1.5 9.3 8.4 6.1 4.4 3.2 3.1 1.6 0.2 7.6 0.0 3.8 1.4 0.4 0.4 0.3 0.2 0.2 1.1 0.3 0.2 0.3 1.8 0.4 0.3 0.9 0.5 0.4 0.4 0.2 0.5 14.1 7.5 15.0 17.0 9.9 8.3 5.6 11.0 8.9 5.5 0.0 5.4 0.8 2.8 2.4 7.4 6.7 10.2 1.4 5.7 17.4 19.6 5.4 0.0 5.6 0.4 6.0 26.4 0.0 3.5 2.2 5.7 6.2 1.1 6.0 1.9 9.5 8.1 4.9 0.3 0.5 10.6 1.1 6.8 1.0 24.4 5.6 8.0 31.6 8.9 2.9 8.6 19.4 16.7 1.2 1.3 1.8 4.2 0.0 19.7 5.8 ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 34.7;granulocytes: 48.6;Hofbauer cells: 30.2;Kupffer cells: 61.4;Macrophages: 41.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 23.3;HMC-1: 65.3;RPMI-8226: 32.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041218, HPA048241" Uncertain Approved Cytosol NA NA Cytosol "HPA041218: AB_2677365, HPA048241: AB_2680326" "unprognostic (1.98e-1)" "prognostic unfavorable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" 6.3 4.3 7.0 17.4 9.7 14.9 3.9 1.2 5.2 3.7 5.0 9.8 0.8 2.8 3.7 4.8 13.2 5.3 6.9 7.3 5.3 4.2 3.3 3.6 16.4 16.5 8.8 4.4 17.1 3.7 1.0 3.4 9.7 8.6 3.5 5.9 6.2 6.5 1.6 1.8 7.9 10.4 5.0 12.3 26.9 4.9 2.1 9.2 21.8 3.7 3.1 26.0 6.6 6.1 3.6 12.5 6.5 16.7 8.4 7.0 5.0 4.0 5.5 0.2 0.8 0.6 7.1 0.5 2.8 1.3 2.2 2.0 5.2 8.4 1.6 7.6 11.4 0.1 14.7 5.8 2.4 2.7 15.4 2.0 23.3 4.2 1.5 6.5 4.4 65.3 3.8 2.4 1.6 2.6 1.2 0.6 5.3 8.5 3.2 3.1 2.3 1.7 10.4 1.0 1.9 7.9 1.6 2.1 32.4 1.5 0.4 1.0 2.7 1.5 0.6 1.3 1.4 0.1 13.0 5.2 0.3 7.6 0.8 0.8 0.3 0.1 3.5 2.4 9.5 1.0 6.5 7.8 2.9 7.0 11.7 5.1 3.2 2.8 5.0 12.5 3.6 2.6 3.7 4.4 8.4 16.7 6.5 3.9 5.0 7.0 9.7 1.2 5.2 5.3 4.2 8.8 4.4 8.6 9.2 17.9 34.7 6.9 0.3 3.3 1.0 0.6 0.0 0.0 12.5 0.0 5.9 9.3 0.0 1.6 1.3 1.0 1.7 0.0 0.2 0.9 11.4 0.3 48.6 0.2 30.2 0.0 0.0 1.8 61.4 0.5 0.6 41.8 5.0 3.6 0.5 0.9 3.1 7.0 1.1 0.0 0.4 6.5 1.4 0.0 0.7 3.4 3.3 18.5 2.1 1.0 ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131042426 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.6;epididymis: 27.8" "Cell type enhanced" "Detected in some" 22 "Cardiomyocytes: 1.0;Early spermatids: 2.5" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 3.9;GAMG: 6.3;U-138 MG: 13.7;U-87 MG: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported NA NA "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" 0.2 0.2 8.2 0.2 5.1 0.2 0.9 5.3 9.6 0.8 0.2 1.2 1.4 0.2 0.3 27.8 0.2 4.8 0.2 0.3 6.4 6.2 0.5 0.2 1.6 0.2 7.8 0.6 0.3 0.2 0.2 0.0 0.2 5.7 0.2 0.2 0.0 2.8 2.0 0.2 1.5 0.2 0.9 5.0 0.2 0.3 0.7 1.1 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.3 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 5.1 5.3 5.0 6.4 6.2 7.8 0.6 5.7 1.1 0.0 1.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116185 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.4" "Cell type enhanced" "Detected in many" 5 "Cholangiocytes: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041328, HPA044225" Approved Approved Cytosol NA NA Cytosol "HPA041328: AB_2677414, HPA044225: AB_2678863" "unprognostic (1.78e-1)" "unprognostic (5.54e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (2.52e-1)" "unprognostic (3.61e-2)" "unprognostic (6.93e-2)" "unprognostic (4.76e-3)" "unprognostic (5.40e-2)" "unprognostic (1.37e-1)" "prognostic favorable (5.24e-8)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.55e-2)" 5.2 4.8 7.1 3.2 10.9 0.9 5.4 8.5 9.6 7.0 6.4 4.1 4.4 6.5 6.5 4.4 6.8 7.7 6.5 13.3 6.2 3.0 8.0 9.6 11.1 2.5 3.0 6.2 9.4 12.5 12.3 5.8 7.8 7.7 3.6 5.5 9.0 10.1 5.0 36.4 4.4 10.9 6.3 2.2 3.2 5.5 4.4 3.4 0.7 21.8 7.7 3.0 7.9 4.8 0.1 1.0 3.2 1.5 1.0 1.9 0.9 4.9 7.6 2.3 4.3 8.3 10.2 3.5 8.8 9.2 4.9 4.0 6.3 4.4 0.0 13.5 24.0 3.0 4.8 9.1 5.4 3.4 6.1 8.8 0.2 17.4 12.1 9.1 0.6 4.0 10.8 8.5 5.7 3.0 4.1 3.3 1.6 2.7 0.0 5.0 9.1 0.0 2.6 4.2 2.1 4.1 7.8 11.1 0.2 1.8 1.3 5.3 2.3 6.8 8.1 5.9 2.7 20.5 8.9 3.0 9.8 2.7 9.5 3.8 1.9 1.1 1.0 2.1 2.7 3.8 3.2 1.5 1.0 1.9 1.5 1.7 0.0 0.6 0.6 0.1 0.1 0.1 1.1 0.3 1.0 0.0 1.0 0.0 0.9 7.1 10.9 8.5 9.6 6.2 3.0 3.0 6.2 7.7 3.4 11.9 10.9 0.5 1.0 5.7 9.3 15.1 28.1 6.7 7.9 12.2 11.8 1.4 0.0 3.8 0.6 5.2 13.6 0.0 4.6 1.7 6.9 0.6 0.0 17.4 1.4 1.6 1.2 8.0 5.9 1.5 7.8 2.6 6.8 1.0 8.4 7.5 2.8 0.0 7.1 4.7 12.8 0.0 13.8 1.1 5.2 3.3 0.8 4.3 5.2 0.9 ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346500-40390463 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol NA NA 180000 Cytosol "CAB019285: , HPA000525: AB_1078106" "unprognostic (2.80e-1)" "unprognostic (2.12e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" "prognostic unfavorable (5.81e-8)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (8.43e-2)" "unprognostic (2.70e-1)" "unprognostic (4.06e-1)" "unprognostic (1.44e-2)" 9.3 11.6 5.0 13.7 8.5 11.2 9.0 6.8 10.1 7.9 9.5 7.3 4.4 6.0 10.8 9.4 9.7 9.0 6.9 14.6 4.5 4.7 12.0 17.3 6.8 17.6 4.9 4.9 10.5 21.8 5.4 9.1 9.5 5.1 7.1 9.7 9.2 14.7 6.4 79.0 6.2 9.4 10.7 4.9 14.5 9.6 10.9 4.4 18.8 8.4 23.6 15.5 9.5 7.4 15.3 28.8 11.0 22.7 19.8 34.0 24.6 21.4 25.3 21.8 31.1 14.7 20.8 25.3 19.6 19.4 42.6 32.5 41.8 12.6 62.4 16.7 22.7 19.4 16.2 48.6 31.6 43.8 16.6 45.7 28.3 28.6 38.5 30.9 92.1 23.8 22.3 17.9 37.4 39.7 21.1 31.4 28.2 33.4 27.4 31.8 24.0 28.4 32.9 35.5 25.9 27.0 43.3 45.8 44.3 27.4 17.0 14.1 13.9 23.4 13.0 37.2 20.0 17.9 29.1 20.8 22.8 42.2 20.1 37.5 26.0 45.4 47.8 19.0 34.2 22.2 11.0 19.3 7.8 16.2 22.7 22.8 15.3 34.0 21.7 28.8 14.9 27.0 20.8 1.9 19.8 20.2 14.9 34.0 24.6 5.0 8.5 6.8 10.1 4.5 4.7 4.9 4.9 5.1 4.4 11.9 9.6 11.9 15.4 16.1 15.9 25.7 20.4 5.3 7.9 3.5 35.3 78.9 6.6 48.2 34.1 17.1 14.2 0.0 38.1 60.7 23.3 13.9 36.8 21.3 54.2 6.4 13.3 33.2 40.2 16.1 23.0 24.7 11.8 41.5 20.7 43.1 33.8 7.0 13.4 13.5 17.0 25.8 17.6 39.7 73.9 13.2 27.7 27.4 37.6 9.3 ALAD "ALADH, PBGS" ENSG00000148218 "Aminolevulinate dehydratase" P13716 9 113386317-113401333 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Allosteric enzyme, Lyase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 84.2" "Cell type enhanced" "Detected in all" 4 "Erythroid cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021023, HPA022124" Enhanced NA NA 44000000 "HPA021023: AB_1844716, HPA022124: AB_1844717" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "prognostic unfavorable (7.33e-5)" "prognostic favorable (5.64e-4)" "unprognostic (4.16e-2)" "unprognostic (9.49e-2)" "prognostic favorable (8.80e-5)" "unprognostic (2.87e-3)" "unprognostic (3.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (3.31e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-2)" 19.9 70.3 24.1 6.4 26.3 27.3 13.7 14.0 24.8 8.3 10.5 28.3 8.8 11.6 7.5 11.5 14.6 6.8 13.0 23.3 24.6 20.8 29.9 84.2 8.4 5.9 37.5 20.6 12.3 18.8 24.1 7.2 10.2 27.9 14.5 10.2 9.8 37.2 15.1 10.6 15.6 10.7 8.9 40.1 5.9 18.1 5.4 28.6 4.7 10.9 6.6 7.5 9.0 8.0 7.6 12.1 19.1 13.1 5.5 9.7 7.6 3.3 5.8 4.6 6.4 32.2 22.1 29.3 9.1 15.3 6.0 7.7 8.1 7.0 4.7 5.6 12.9 4.6 12.4 3.3 6.3 3.5 11.7 4.2 9.3 7.3 10.6 7.3 8.5 8.0 18.7 4.7 5.5 2.4 23.9 11.8 7.9 3.5 7.0 9.9 24.5 9.8 8.4 2.3 24.4 11.6 7.7 8.0 8.1 9.4 7.1 4.2 4.0 11.6 14.1 8.3 8.7 14.8 9.8 12.8 5.4 4.1 10.6 5.1 10.5 9.8 3.7 15.1 7.9 5.8 7.2 11.5 19.1 9.7 13.1 5.4 5.9 8.4 5.4 12.1 7.6 8.1 8.9 5.6 5.5 12.7 4.9 8.5 7.6 24.1 26.3 14.0 24.8 24.6 20.8 37.5 20.6 27.9 28.6 14.9 14.1 10.2 9.3 6.3 12.5 50.8 17.8 10.7 9.1 14.0 25.5 36.1 11.6 14.5 4.7 12.8 25.6 70.0 23.3 18.1 9.4 7.0 13.9 55.7 15.4 4.8 8.7 12.9 16.7 6.9 10.9 10.2 11.8 5.4 13.8 5.8 15.3 28.8 13.8 42.7 14.9 6.5 9.9 6.2 7.5 8.0 9.5 6.9 16.9 6.8 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease mutation, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 1296.2" "Group enriched" "Detected in some" 13284 "Cardiomyocytes: 1628.0;Cytotrophoblasts: 1088.2;Extravillous trophoblasts: 1710.3;Hofbauer cells: 1077.0;Syncytiotrophoblasts: 1138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA004177, CAB006252" Enhanced Approved Cytosol NA NA 1200000000 Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 27.9 30.9 34.7 24.2 42.3 36.0 25.3 31.2 59.7 21.0 32.8 16.3 25.9 29.4 21.9 33.9 73.5 22.1 24.4 109.3 31.6 33.4 28.2 11.1 17.9 34.0 35.0 49.6 23.4 19.4 51.0 25.2 19.9 38.0 23.6 23.5 24.6 37.9 36.9 1296.2 28.4 21.5 30.1 22.7 17.4 24.4 9.2 18.9 18.5 26.6 189.8 29.0 36.8 27.7 61.1 142.9 165.7 166.3 50.5 93.2 217.0 138.8 104.7 31.5 101.2 48.3 55.1 100.7 84.1 87.6 85.8 107.3 74.0 107.1 94.7 137.9 84.8 47.1 106.1 63.2 183.3 63.0 41.6 83.1 77.5 84.0 163.3 75.5 112.6 83.2 75.5 64.7 96.3 64.7 141.5 63.1 44.7 66.6 62.5 90.9 198.0 68.4 93.0 78.4 54.0 88.3 102.2 50.6 211.6 106.8 79.1 63.1 44.4 52.4 221.3 78.4 41.1 94.1 76.4 75.0 126.7 50.6 69.1 90.9 123.6 84.3 86.6 235.7 109.4 100.0 106.7 164.0 130.3 70.2 156.8 79.1 61.1 76.8 72.5 142.9 55.5 73.8 70.3 165.7 50.5 166.3 53.8 93.2 217.0 34.7 42.3 31.2 59.7 31.6 33.4 35.0 49.6 38.0 18.9 0.0 0.0 0.0 0.0 0.0 0.0 1628.0 0.0 0.0 0.0 0.0 0.0 1088.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1710.3 0.0 0.0 0.0 0.0 1077.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1138.4 0.0 0.0 0.0 ALDOA ENSG00000285043 "Aldolase, fructose-bisphosphate A" P04075 16 30053090-30070420 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Glycolysis Lyase "Cancer-related genes, Disease mutation, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 1558.3" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA004177 Uncertain Approved Cytosol NA NA 1200000000 Cytosol "HPA004177: AB_1078128" 1.8 0.9 2.7 1.1 5.0 2.1 7.2 0.7 7.7 4.9 1.5 2.0 2.4 0.0 2.5 3.9 0.9 3.6 1.6 5.3 2.3 1.3 0.0 2.3 2.0 0.8 4.4 2.2 0.8 0.8 3.0 1.4 4.0 2.4 0.5 2.8 1.6 7.5 10.6 0.6 0.1 1.9 0.4 1.7 1.3 11.6 0.8 1.2 4.7 0.2 2.7 1.2 1.0 7.0 6.6 0.9 6.2 4.2 8.5 12.5 3.8 8.9 1.9 6.2 1.5 5.2 1.5 4.1 7.0 5.5 21.8 3.6 5.1 24.7 6.0 6.8 1.8 6.4 14.1 11.1 3.8 4.4 8.0 6.0 8.3 6.0 11.6 10.6 2.3 5.1 0.5 10.8 12.4 4.5 7.8 4.0 1.2 7.2 13.5 3.9 5.0 8.1 2.1 1.7 5.6 7.7 4.0 22.7 15.3 0.7 6.2 5.1 1.0 1.7 1.5 0.6 5.2 4.0 1.7 8.1 2.5 3.7 5.4 7.4 5.5 8.1 7.7 11.5 3.5 0.1 6.2 0.1 5.3 2.6 7.4 7.0 7.0 5.7 6.6 6.2 8.5 6.6 0.9 4.2 2.3 5.6 5.4 12.5 11.9 25.9 269.9 530.0 703.6 362.0 0.0 315.9 36.1 40.9 40.1 111.9 0.0 94.5 100.6 190.1 242.7 1558.3 46.7 66.6 0.0 38.0 448.8 200.0 94.7 0.0 692.8 311.1 289.1 683.7 930.6 352.7 289.5 877.3 70.3 597.6 553.3 106.3 971.1 380.8 45.3 219.0 478.6 664.3 23.8 81.3 598.3 0.0 258.9 731.1 912.8 ALDOB ENSG00000136872 "Aldolase, fructose-bisphosphate B" P05062 9 101420578-101435823 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "intestine: 804.1;kidney: 253.1;liver: 598.8" "Group enriched" "Detected in many" 9 "Hepatocytes: 2651.5;Proximal tubular cells: 6429.5" "Cancer enriched" "Detected in many" 31 "liver cancer: 1414.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.4;NB-4: 13.5;RPMI-8226: 15.6;SH-SY5Y: 13.5;U-2197: 5.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA002198, CAB020827" Enhanced NA NA 930000000 "CAB020827: , HPA002198: AB_1078129" "unprognostic (6.58e-3)" "unprognostic (2.83e-1)" "unprognostic (1.43e-3)" "unprognostic (1.03e-1)" "unprognostic (8.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (4.57e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (7.48e-2)" "unprognostic (1.66e-2)" "unprognostic (2.02e-1)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (1.96e-2)" 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.2 0.1 334.5 0.2 0.2 145.9 0.2 0.6 0.1 0.1 5.7 0.1 0.1 0.1 253.1 598.8 0.1 0.1 0.1 0.1 0.1 18.3 0.0 0.4 0.1 0.4 0.1 0.0 0.2 0.2 0.1 0.1 0.1 804.1 0.1 0.1 0.2 1.5 0.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.4 0.0 3.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.4 0.0 3.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.2 13.5 0.2 0.4 0.0 0.2 3.1 15.6 0.0 0.0 2.6 13.5 1.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.7 5.4 0.2 0.4 0.2 1.6 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 48.6 0.0 0.0 1.0 0.9 448.4 0.0 0.0 143.1 0.0 0.0 525.6 3.8 0.0 0.0 62.6 46.7 221.2 0.0 0.0 0.0 0.0 2651.5 0.2 3.2 0.0 50.3 57.0 0.0 0.0 0.0 0.0 6.4 2.6 0.4 297.3 28.8 0.0 6429.5 0.6 0.0 0.0 0.0 0.0 0.0 0.2 5.0 1.5 0.0 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28577264 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 166.7;heart muscle: 56.9" "Cell type enhanced" "Detected in many" 11 "Cone photoreceptor cells: 100.1;Horizontal cells: 259.0;Rod photoreceptor cells: 259.1" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 63.4;U-266/70: 43.8;U-87 MG: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 280000000 "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 26.0 9.4 86.7 4.8 78.9 7.5 9.8 100.1 166.7 3.8 5.3 17.4 0.3 7.0 4.4 4.6 7.1 3.9 4.4 56.9 64.6 54.3 3.3 26.2 4.6 6.5 69.9 51.4 12.8 1.6 4.7 2.3 2.1 98.1 6.0 5.6 16.5 4.2 6.1 1.7 12.5 15.0 4.6 34.4 6.7 8.7 4.6 23.4 0.0 2.1 0.5 10.0 3.4 3.5 12.2 4.6 8.8 4.1 13.7 20.5 8.8 7.5 0.5 3.5 14.7 7.4 7.6 0.7 3.9 8.8 3.0 18.5 4.4 0.7 3.5 4.6 3.4 0.8 9.9 2.4 24.1 5.6 3.1 2.3 6.8 2.8 7.5 6.9 2.5 8.0 7.0 3.4 0.3 6.0 0.4 1.3 7.3 4.6 19.1 2.6 3.6 2.9 8.3 5.5 1.6 3.9 2.4 0.4 63.4 0.4 1.0 9.4 16.7 2.2 18.1 0.1 5.8 9.8 5.6 0.9 0.3 1.4 0.5 0.6 43.8 12.5 2.6 28.6 7.1 0.5 0.1 3.5 1.4 11.4 4.1 16.2 12.2 15.6 9.2 4.6 11.5 20.5 15.1 8.8 13.7 2.3 2.2 19.5 8.8 86.7 78.9 100.1 78.5 64.6 54.3 69.9 51.4 98.1 23.4 0.0 12.0 9.3 17.7 6.6 72.2 19.0 5.1 0.0 7.9 7.0 100.1 1.2 3.3 14.2 0.8 8.4 22.7 0.0 8.9 3.9 7.1 4.4 12.7 50.8 4.4 259.0 20.7 16.5 4.7 0.8 8.6 3.7 23.6 58.7 8.7 81.4 11.6 14.0 9.6 1.6 259.1 12.9 17.6 0.4 3.2 9.5 1.3 17.0 3.3 8.0 ALKBH1 "ABH, alkB, ALKBH, hABH" ENSG00000100601 "AlkB homolog 1, histone H2A dioxygenase" Q13686 14 77672404-77708020 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, RNA repair, Translation regulation" "Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044087, HPA060061" Approved Supported "Nucleoplasm,Endoplasmic reticulum" "Intracellular and membrane" NA NA Nucleoplasm "Endoplasmic reticulum" "HPA044087: AB_2678803, HPA060061: " "unprognostic (1.92e-2)" "unprognostic (8.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-3)" "unprognostic (3.41e-2)" "unprognostic (5.03e-2)" "unprognostic (3.74e-3)" "unprognostic (7.45e-3)" "unprognostic (2.68e-2)" "unprognostic (3.95e-2)" "unprognostic (5.05e-3)" "unprognostic (2.16e-2)" "prognostic favorable (1.80e-4)" "unprognostic (1.65e-3)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.44e-2)" 8.2 8.5 6.2 6.7 8.6 2.7 9.7 9.6 8.8 9.7 9.1 8.2 4.5 6.5 7.0 5.9 7.1 8.0 5.8 11.1 5.4 5.7 7.9 9.4 5.9 8.3 6.5 3.7 8.3 7.9 8.4 11.2 10.2 6.4 9.3 9.1 9.9 7.2 8.7 16.5 8.2 6.7 7.8 5.5 8.3 7.8 9.9 6.6 12.7 8.8 6.5 10.3 8.5 9.4 5.4 4.9 11.4 5.7 5.2 5.3 3.2 5.3 8.0 6.5 4.4 7.0 7.7 8.2 5.6 7.3 12.4 14.0 8.1 3.3 8.3 3.2 5.1 5.8 4.9 14.2 6.1 14.7 5.6 5.6 4.4 4.7 6.8 9.9 4.6 2.9 6.5 10.1 7.3 11.6 5.5 10.1 6.5 6.8 4.8 6.6 8.5 6.2 6.0 7.2 8.1 10.3 6.2 6.6 5.5 7.1 4.8 8.4 6.3 4.6 4.8 6.1 5.6 11.8 4.8 4.6 5.2 5.3 5.7 4.5 6.0 9.5 8.1 3.5 6.7 5.1 11.4 5.0 2.2 5.0 5.7 4.3 5.4 4.7 5.0 4.9 4.9 5.0 3.9 1.4 5.2 3.8 2.6 5.3 3.2 6.2 8.6 9.6 8.8 5.4 5.7 6.5 3.7 6.4 6.6 0.0 4.6 3.7 4.9 7.4 4.0 6.5 0.0 5.3 3.4 1.8 2.0 8.9 8.3 5.3 3.3 4.1 4.2 0.0 6.1 6.7 6.0 3.8 9.2 3.0 6.5 0.0 2.4 3.1 4.6 3.1 6.1 5.6 5.0 5.4 4.6 7.3 5.7 0.0 4.9 5.1 4.9 6.5 5.2 15.8 14.9 4.6 10.2 4.4 4.2 3.0 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 30.2" "Cell type enhanced" "Detected in some" 12 "Basal glandular cells: 1.6;Glandular cells: 2.0;Pancreatic endocrine cells: 3.6;Spermatogonia: 1.5;Suprabasal keratinocytes: 1.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.9" "Group enriched" "Detected in many" 8 "basal ganglia: 1.1;cerebellum: 1.4;cerebral cortex: 2.3;pons and medulla: 1.1" "Group enriched" "Detected in some" 5 "gdT-cell: 1.0;naive CD4 T-cell: 2.7" "Lineage enriched" "Detected in single" 28 "T-cells: 2.7" "Cell line enhanced" "Detected in some" "A-431: 6.6;HBEC3-KT: 10.8;hTCEpi: 8.0;hTERT-HME1: 15.1;T-47d: 4.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.1 0.0 0.1 0.1 1.1 0.0 1.6 1.4 2.3 1.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 1.1 0.1 0.0 0.1 0.1 0.1 0.1 30.2 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 1.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 2.7 0.2 6.6 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.4 0.1 0.5 0.2 0.2 0.1 3.2 0.5 0.9 10.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.0 0.2 15.1 0.0 0.0 1.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.8 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.1 1.4 2.3 0.1 0.1 0.1 0.1 1.1 0.1 0.0 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.9 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.5 1.6 0.9 0.0 0.0 0.7 AMD1 SAMDC ENSG00000123505 "Adenosylmethionine decarboxylase 1" P17707 6 110874770-110895713 "Enzymes, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 104.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029281, HPA029282" Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA029281: AB_10600101, HPA029282: AB_10599965" "prognostic unfavorable (3.87e-4)" "unprognostic (4.68e-2)" "unprognostic (1.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.91e-6)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (6.50e-2)" "unprognostic (2.25e-1)" "unprognostic (4.20e-1)" "prognostic favorable (4.28e-4)" "unprognostic (8.62e-3)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (7.71e-2)" 16.7 15.2 29.7 16.9 35.6 38.1 17.8 27.3 34.2 18.6 18.6 45.7 12.5 14.9 18.9 14.2 28.9 14.7 17.5 18.5 32.5 21.5 25.2 16.9 16.9 18.5 39.0 22.0 16.9 20.2 21.8 26.2 33.8 32.7 104.7 19.4 12.8 17.5 19.2 15.3 14.5 13.5 18.4 38.3 16.7 18.4 15.8 46.0 19.4 25.5 20.1 24.6 12.6 16.8 6.6 12.9 42.0 14.0 6.1 9.2 6.5 20.8 14.3 17.5 33.1 26.5 16.9 22.9 30.1 33.4 23.5 27.7 22.7 13.2 36.9 14.6 19.0 25.0 14.4 41.3 27.2 32.4 21.6 23.9 38.2 13.0 23.8 15.8 32.9 22.9 11.3 25.2 16.2 32.8 8.2 20.4 19.0 28.5 32.2 39.5 12.6 43.7 25.3 21.5 20.8 13.1 24.1 17.6 21.9 26.6 28.0 22.5 16.0 18.3 23.3 26.5 14.9 15.0 28.2 13.4 15.6 11.8 83.0 32.4 8.8 14.3 37.7 18.0 26.4 20.0 15.0 9.8 14.7 7.6 11.6 8.9 6.3 7.6 8.7 12.9 6.6 9.2 9.0 42.0 6.1 14.0 5.8 8.8 6.5 29.7 35.6 27.3 34.2 32.5 21.5 39.0 22.0 32.7 46.0 35.7 72.7 96.8 225.1 280.1 92.0 87.2 86.6 30.8 108.1 52.4 56.9 32.2 124.3 65.9 25.2 75.1 78.4 70.0 59.9 125.5 124.4 304.0 93.3 52.5 68.2 73.1 119.2 47.9 101.7 37.7 40.6 70.6 124.9 74.9 52.0 241.3 72.3 49.3 47.0 70.8 99.1 19.4 119.5 83.5 72.8 251.9 45.7 59.8 63.1 119.5 APEX1 "APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1" ENSG00000100823 "Apurinic/apyrimidinic endodeoxyribonuclease 1" P27695 14 20455191-20457772 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000956, HPA002564, CAB004294, CAB047307" Supported Supported Nucleoplasm Yes No 98000 Nucleoplasm "CAB004294: AB_626685, CAB047307: , HPA000956: AB_2666158, HPA002564: AB_1078174" "unprognostic (2.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.55e-2)" "unprognostic (4.74e-3)" "unprognostic (1.97e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (4.21e-2)" "unprognostic (3.14e-2)" "unprognostic (2.46e-2)" "unprognostic (2.42e-2)" "unprognostic (1.68e-1)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-2)" "unprognostic (2.54e-1)" "unprognostic (7.08e-2)" 43.9 52.8 30.6 33.2 32.5 55.6 43.6 24.1 44.9 38.5 41.9 37.3 28.4 44.1 53.2 30.1 40.7 42.9 46.4 34.4 28.0 27.4 44.4 61.3 31.8 44.5 30.2 31.1 64.7 48.4 31.8 21.7 29.4 34.4 36.1 39.8 36.0 35.5 38.9 53.2 41.2 37.6 40.9 30.1 51.0 41.7 20.9 28.3 73.2 51.2 38.5 48.4 41.8 32.7 35.0 53.0 1.5 23.7 20.6 32.5 38.4 44.6 54.9 49.3 45.4 34.7 50.1 42.5 42.0 45.2 62.6 54.3 40.0 44.4 86.3 37.5 32.0 33.5 47.9 58.6 44.4 58.2 38.5 25.0 34.9 32.5 66.7 36.5 110.9 36.3 51.7 49.0 40.7 40.4 50.2 52.2 35.7 40.5 28.4 50.1 43.5 71.0 46.7 48.5 50.7 49.7 79.0 55.4 36.2 52.5 60.3 59.5 37.8 45.5 56.8 45.1 36.3 34.5 50.2 33.7 33.0 55.4 33.2 39.1 38.2 66.1 58.2 14.8 70.5 41.7 0.1 23.7 1.5 19.0 20.5 25.9 35.0 23.8 22.6 46.8 31.4 32.5 28.3 1.5 20.6 12.4 53.0 14.1 38.4 30.6 32.5 24.1 44.9 28.0 27.4 30.2 31.1 34.4 28.3 59.6 45.2 101.2 74.7 94.4 52.3 42.8 86.6 72.3 79.6 64.6 39.3 161.9 127.6 119.2 16.8 57.5 33.9 0.0 91.3 165.4 86.9 49.2 78.7 65.2 158.8 27.0 115.1 39.3 80.7 4.0 74.5 109.4 60.8 100.0 78.8 68.5 83.2 73.7 60.5 126.7 45.4 51.8 136.6 6.3 43.7 84.8 84.9 76.1 136.8 42.5 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000357-55009057 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 11.1 12.8 8.6 12.0 12.3 11.9 10.2 8.7 11.8 10.0 12.3 13.7 8.2 12.3 11.5 12.6 20.8 10.7 13.9 10.6 8.7 7.2 15.4 18.5 10.3 14.2 9.7 6.0 14.4 10.7 10.7 12.7 17.8 8.8 11.0 15.1 9.1 10.4 10.0 10.3 16.7 18.7 10.0 9.9 18.0 10.8 7.7 8.9 21.9 10.6 10.2 27.4 11.6 12.7 6.7 9.4 9.2 9.9 26.6 7.5 6.3 22.0 19.9 7.9 11.4 11.5 7.7 13.4 9.1 12.3 17.7 17.3 10.8 18.6 14.6 14.3 8.6 20.9 16.6 18.0 17.3 13.4 11.8 13.7 17.8 19.8 11.0 7.4 10.9 16.8 7.6 14.2 24.9 9.0 8.4 14.0 15.6 9.1 9.9 13.1 21.5 14.7 14.3 15.6 10.5 24.0 13.1 13.1 15.9 9.5 11.1 7.3 8.0 17.2 20.9 8.8 18.8 16.5 8.5 8.1 10.5 15.3 21.1 11.8 10.4 13.3 12.1 11.2 18.7 12.4 9.2 7.8 8.5 7.5 9.9 6.2 6.1 7.1 7.4 9.4 6.7 6.4 6.2 2.9 26.6 8.3 5.1 7.5 6.3 8.6 12.3 8.7 11.8 8.7 7.2 9.7 6.0 8.8 8.9 3.0 16.9 15.2 10.8 11.4 3.2 4.7 10.2 12.0 9.1 10.4 0.0 43.2 13.3 21.7 0.2 7.7 13.7 70.0 13.2 28.4 7.0 7.8 8.1 10.2 21.2 6.4 5.8 8.6 8.6 0.8 5.5 13.5 0.0 29.7 11.1 5.8 15.0 14.8 8.1 15.8 2.1 19.4 4.4 1.0 10.8 11.0 39.8 15.8 11.3 10.0 APIP "APIP2, CGI-29, Mmrp19" ENSG00000149089 "APAF1 interacting protein" Q96GX9 11 34853094-34916499 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Apoptosis, Methionine biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Distal tubular cells: 159.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021188, HPA024131" Approved Approved Nucleoplasm,Cytosol NA NA 77000 Nucleoplasm Cytosol "HPA021188: AB_10610977, HPA024131: AB_10602171" "unprognostic (2.80e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-2)" "unprognostic (3.68e-3)" "unprognostic (4.22e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.74e-2)" "unprognostic (3.84e-2)" "unprognostic (9.16e-2)" "unprognostic (2.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-1)" "unprognostic (3.23e-1)" "unprognostic (5.48e-2)" "unprognostic (7.44e-2)" "unprognostic (1.58e-2)" 23.2 29.8 12.0 13.7 18.7 9.6 15.8 7.6 12.6 12.7 13.8 17.9 16.8 10.5 15.3 10.8 12.2 13.9 12.1 15.4 14.5 11.7 24.8 21.8 16.2 14.4 21.5 11.7 13.2 19.7 13.4 10.3 12.5 21.1 14.1 12.6 10.4 18.5 20.4 48.7 6.8 13.9 16.0 27.8 13.9 19.1 9.7 21.1 23.9 19.0 12.9 11.5 19.0 16.1 14.2 25.6 14.9 19.8 17.5 15.8 10.6 8.6 9.3 11.0 2.6 9.0 9.0 4.9 12.8 12.3 12.6 14.4 5.5 7.6 26.6 7.8 4.7 13.0 10.4 20.1 8.6 16.3 16.3 19.1 13.7 9.9 13.9 13.9 38.0 10.5 8.8 6.4 8.0 13.2 5.6 10.3 15.5 32.2 16.4 8.7 8.3 18.1 17.5 8.8 11.8 22.0 11.7 32.3 9.1 13.0 12.5 9.3 4.5 16.1 12.9 15.7 5.5 13.5 11.8 8.6 9.5 9.6 24.3 3.1 16.1 12.0 30.0 11.8 8.1 12.1 4.7 16.9 14.9 11.0 17.5 13.6 14.2 13.4 11.9 25.6 13.4 13.8 11.7 4.1 17.5 19.8 16.5 15.8 10.6 12.0 18.7 7.6 12.6 14.5 11.7 21.5 11.7 21.1 21.1 32.8 26.7 21.4 29.7 22.1 22.7 19.8 40.8 48.2 28.4 17.4 3.9 31.1 159.2 23.6 5.4 20.4 30.7 23.3 28.4 20.1 20.0 35.6 19.7 21.2 67.0 17.5 34.1 22.1 46.7 7.4 22.2 39.5 20.3 66.7 30.2 16.6 21.6 24.6 23.3 70.8 21.9 38.8 25.8 22.8 24.0 23.1 22.1 24.1 38.3 41.1 APLF "C2orf13, MGC47799, Xip1, ZCCHH1" ENSG00000169621 "Aprataxin and PNKP like factor" Q8IW19 2 68467561-68655862 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 19 "Early spermatids: 110.5;Late spermatids: 132.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 9.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 9.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029396, HPA034642, HPA034643" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA029396: AB_10610285, HPA034642: AB_2674259, HPA034643: AB_10602431" "unprognostic (9.37e-2)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (4.29e-3)" "unprognostic (5.18e-3)" "unprognostic (2.39e-3)" "unprognostic (3.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.00e-2)" "unprognostic (2.78e-1)" "unprognostic (1.25e-3)" "unprognostic (3.28e-1)" "unprognostic (5.02e-3)" "unprognostic (8.44e-2)" "unprognostic (5.95e-2)" "unprognostic (1.35e-2)" "unprognostic (1.85e-3)" 5.2 4.4 3.8 7.3 6.5 2.8 8.2 1.1 5.0 8.0 5.7 3.1 3.8 2.6 8.8 4.0 10.6 3.3 4.1 3.8 4.7 2.0 3.7 5.1 3.4 5.8 3.6 2.1 4.3 3.8 4.1 5.1 6.2 3.2 8.5 2.7 2.3 6.4 4.8 5.4 9.2 3.3 9.2 5.6 5.7 3.6 4.1 6.1 5.1 4.4 7.5 5.8 6.9 6.9 1.1 1.4 9.3 1.2 1.5 2.2 0.9 3.6 0.9 4.1 4.1 5.5 7.4 2.1 3.2 5.8 1.9 2.4 2.3 3.0 6.7 2.6 2.6 4.5 1.2 0.5 4.4 4.6 6.2 0.8 5.5 0.8 1.4 2.6 1.9 4.9 4.1 3.7 2.7 4.1 4.9 1.4 4.2 1.1 4.8 1.9 0.6 2.7 5.0 2.3 3.6 1.6 3.6 1.4 3.0 3.8 2.0 1.2 2.7 3.2 0.4 3.8 6.0 0.3 1.1 3.6 6.7 1.5 3.4 2.5 4.4 2.4 5.2 2.9 2.7 4.4 9.3 0.9 3.1 0.9 1.2 1.0 1.1 1.4 1.3 1.3 1.0 1.5 0.8 0.0 1.5 0.9 1.4 2.2 0.9 3.8 6.5 1.1 5.0 4.7 2.0 3.6 2.1 3.2 6.1 3.0 1.6 0.9 2.2 2.2 0.1 2.6 0.0 1.4 3.4 0.0 2.0 5.3 0.0 2.7 110.5 2.5 0.0 0.0 1.7 2.0 2.3 1.5 0.0 0.8 1.9 3.2 3.4 2.5 0.3 132.8 4.0 1.7 0.0 6.4 0.5 0.5 0.9 0.0 1.8 1.9 0.3 0.0 2.7 5.0 3.9 2.9 4.1 0.0 0.7 1.3 ASL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075798-66093558 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.5" "Cell type enhanced" "Detected in many" 9 "Enterocytes: 226.8;Hepatocytes: 477.5;Paneth cells: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 10000000 Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" 5.6 4.8 4.0 8.0 4.3 7.3 5.9 7.2 7.4 5.5 17.2 3.7 7.8 20.8 5.0 7.1 7.7 4.9 19.5 4.3 3.7 4.3 16.0 99.5 8.1 4.5 4.4 6.2 5.9 10.4 3.3 5.8 3.3 7.2 5.4 12.4 5.8 7.1 5.7 2.4 4.1 16.6 3.4 3.2 8.6 12.6 2.1 3.5 1.2 7.1 7.9 5.9 5.2 5.9 8.6 19.3 20.7 18.4 30.4 9.2 10.7 18.2 7.5 4.1 14.8 9.5 7.3 9.0 12.8 11.2 18.3 16.7 16.9 22.6 5.6 20.5 16.8 13.3 5.0 2.6 21.7 5.3 4.6 3.4 7.4 7.3 26.1 17.7 8.4 21.7 13.7 7.9 12.8 20.5 4.6 18.0 4.0 13.1 10.7 10.1 13.0 1.7 11.6 6.2 22.8 9.7 4.5 4.3 19.3 13.3 11.0 7.1 9.7 11.7 40.8 4.4 4.4 17.8 7.6 20.4 23.2 12.0 9.2 16.5 11.7 6.1 7.3 21.9 16.0 18.7 12.1 18.1 20.7 7.7 18.4 6.5 8.6 5.2 6.1 19.3 5.6 3.7 4.0 4.0 30.4 13.8 1.2 9.2 10.7 4.0 4.3 7.2 7.4 3.7 4.3 4.4 6.2 7.2 3.5 17.9 52.0 20.8 16.7 4.8 12.5 7.1 132.5 38.8 15.9 29.6 21.6 19.3 44.7 51.9 3.5 25.6 226.8 0.0 192.3 35.3 14.5 13.1 44.9 477.5 40.4 14.3 51.9 35.6 39.6 4.9 8.6 16.1 8.5 61.3 87.3 6.5 99.6 217.5 7.8 174.9 12.2 12.9 13.9 3.0 5.8 3.8 18.7 27.5 126.5 20.6 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361913 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Distal tubular cells: 162.5;Proximal tubular cells: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 13.0 39.6 14.3 15.6 20.1 3.8 15.2 22.5 20.7 14.1 19.8 10.5 25.3 19.2 11.1 16.0 8.9 10.7 11.4 30.4 15.4 19.7 50.4 21.3 9.7 6.7 19.1 9.0 11.8 20.7 27.0 10.1 13.1 16.3 23.8 14.4 10.6 20.1 35.4 31.0 6.7 16.0 10.4 15.2 7.7 17.7 6.1 12.1 9.1 17.5 11.8 8.9 10.2 10.5 8.7 5.8 16.1 4.6 9.9 10.0 5.3 4.6 4.5 6.3 3.2 7.9 8.5 9.8 4.1 5.2 3.2 3.7 2.5 5.9 5.4 4.3 4.4 9.7 6.8 9.4 5.2 4.6 41.8 8.0 3.7 4.9 15.0 6.0 5.3 3.9 7.0 6.6 2.6 9.0 7.6 3.9 5.6 5.1 8.2 3.8 4.4 7.3 12.0 7.9 11.3 6.5 4.3 5.1 9.3 14.1 2.5 6.5 4.7 6.2 14.9 7.8 15.1 2.7 3.5 4.0 3.2 4.1 4.7 4.0 9.4 7.9 1.8 5.1 4.3 2.2 15.2 4.6 16.1 6.9 3.2 7.9 7.8 7.6 10.0 4.2 8.7 9.6 8.8 7.1 9.9 2.1 5.8 9.3 5.3 14.3 20.1 22.5 20.7 15.4 19.7 19.1 9.0 16.3 12.1 0.0 7.7 5.2 22.9 4.6 17.8 32.7 28.1 13.4 4.5 26.2 23.6 37.5 162.5 21.0 2.6 11.2 33.1 23.3 14.0 23.8 11.3 45.7 1.1 16.0 11.6 12.7 22.0 11.1 9.4 1.0 13.3 7.6 11.8 44.1 16.4 8.5 13.9 23.7 10.6 92.2 32.2 12.9 7.5 9.4 11.7 3.6 30.4 13.1 23.0 22.0 CA1 Car1 ENSG00000133742 "Carbonic anhydrase 1" P00915 8 85327608-85379014 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 156.0;intestine: 203.6" "Cell type enriched" "Detected in some" 19 "Erythroid cells: 11890.7" "Group enriched" "Detected in some" 10 "colorectal cancer: 3.4;stomach cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 1207 "HEL: 169.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA006558, CAB025790" Enhanced NA NA 7800000000 "CAB025790: , HPA006558: AB_1845989" "unprognostic (1.44e-1)" "unprognostic (7.56e-2)" "unprognostic (1.70e-1)" "unprognostic (3.57e-3)" "unprognostic (2.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.84e-2)" "unprognostic (2.03e-2)" "unprognostic (1.73e-2)" "unprognostic (6.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (5.61e-2)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" 1.8 0.4 0.5 11.5 0.5 156.0 0.4 0.3 0.4 0.3 95.4 1.5 0.0 0.0 0.3 0.0 0.6 0.7 0.0 17.6 0.5 0.4 0.8 2.9 32.2 0.2 0.9 0.0 0.8 0.5 0.0 1.0 24.0 0.6 1.1 203.6 2.6 0.3 0.1 3.1 0.2 0.4 3.2 0.5 14.3 0.3 0.3 0.0 0.2 7.5 0.0 0.2 4.5 16.0 0.7 0.7 0.0 0.3 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 7.5 0.5 0.5 0.3 0.4 0.5 0.4 0.9 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 624.8 11890.7 0.0 0.0 0.0 0.1 23.0 0.6 0.0 0.0 44.0 1.3 1.6 0.0 0.0 0.0 0.0 0.0 89.9 0.0 0.0 422.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.0 CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63382161 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" Lyase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.5" "Cell type enhanced" "Detected in many" 9 "Basal keratinocytes: 155.1;Enterocytes: 240.0;Paneth cells: 157.9;Suprabasal keratinocytes: 220.4" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 39.0;ASC TERT1: 41.1;RT4: 41.3;SK-BR-3: 33.1;T-47d: 53.4;U-138 MG: 57.0;U-87 MG: 68.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008773, CAB025181, CAB062549, CAB068179" Enhanced NA NA 29000 "CAB025181: , CAB062549: AB_2665617, CAB068179: AB_2665616, HPA008773: AB_1078394" "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" 3.7 0.3 4.7 15.0 27.4 0.3 14.5 3.7 2.3 15.7 32.0 2.6 5.0 0.4 9.8 12.3 42.8 8.5 2.6 1.6 4.9 1.4 103.5 0.3 1.2 0.3 1.8 0.2 2.1 43.8 0.3 3.9 5.9 16.9 3.8 30.3 8.5 8.2 17.9 0.5 44.1 2.4 18.1 0.1 0.4 2.2 1.3 6.7 0.0 1.7 18.4 25.9 10.6 14.5 0.3 0.2 0.6 0.7 0.3 0.2 0.0 0.0 39.0 0.6 0.1 5.2 41.1 2.1 2.8 2.5 0.4 0.7 0.2 0.1 0.0 9.6 2.3 15.4 0.2 0.0 1.9 1.1 0.0 1.4 0.0 2.6 0.0 0.1 0.0 0.0 15.5 2.1 11.9 3.8 0.0 0.5 0.0 0.0 0.0 0.5 22.4 0.0 0.0 0.6 0.0 6.1 0.0 0.0 0.0 0.0 41.3 0.3 0.0 0.1 33.1 0.0 0.4 53.4 0.0 0.0 57.0 3.0 1.8 0.0 0.0 0.0 0.0 68.4 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.6 0.3 0.7 0.2 0.1 0.0 4.7 27.4 3.7 1.3 4.9 1.4 1.8 0.2 16.9 6.7 0.0 5.8 1.5 18.6 155.1 0.0 0.6 0.0 2.7 3.4 38.4 0.0 0.4 46.4 14.9 12.0 0.0 240.0 0.0 48.3 1.7 5.1 14.8 1.1 0.0 0.6 0.0 8.1 0.0 0.0 3.0 0.0 2.2 21.9 0.0 92.2 2.5 15.0 157.9 0.0 59.0 0.2 0.0 3.9 0.0 0.0 220.4 1.5 0.0 95.7 16.3 CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.7" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 12.5;OE19: 24.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 100000 Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" 2.6 2.6 2.0 1.9 3.1 0.5 2.9 2.4 2.4 3.2 18.2 0.8 0.0 14.2 1.8 1.7 6.7 1.4 25.6 5.8 1.6 1.9 10.4 17.1 9.5 2.4 2.0 0.1 2.2 1.6 9.3 6.5 1.0 5.7 2.6 3.7 1.9 7.0 1.0 1.9 7.1 56.7 1.9 5.2 2.2 7.0 0.9 0.9 0.4 10.3 3.9 5.6 2.9 5.2 0.8 2.1 3.2 2.5 0.5 0.5 1.0 0.2 0.3 0.7 0.1 0.5 0.5 0.3 0.8 0.9 0.1 2.4 5.8 4.5 0.3 0.4 1.0 5.1 1.9 1.8 2.3 0.1 1.3 0.8 12.5 1.6 5.3 1.2 0.2 0.5 1.9 0.4 0.2 1.0 1.5 1.3 0.5 3.1 2.4 2.1 0.0 0.2 0.2 0.3 24.6 0.3 0.2 1.8 0.1 6.7 0.2 0.2 0.0 0.4 0.0 1.3 0.9 0.4 0.6 1.2 2.3 3.3 0.1 1.3 1.0 0.4 1.5 4.8 1.8 2.2 3.2 2.5 1.3 0.4 0.7 0.2 0.2 0.2 0.1 2.1 0.8 0.3 0.5 0.9 0.5 0.8 0.9 0.1 1.0 2.0 3.1 2.4 2.4 1.6 1.9 2.0 0.1 5.7 0.9 3.0 7.7 1.4 2.1 1.5 1.5 5.2 5.1 10.7 12.5 12.2 31.4 0.2 8.3 3.2 9.1 2.1 16.9 0.0 1.4 0.2 3.1 2.1 0.0 4.7 0.9 0.0 4.6 9.8 3.0 10.4 0.0 2.2 5.0 0.0 3.2 2.0 3.1 4.9 0.0 16.1 5.1 0.0 1.0 1.2 2.3 2.8 0.2 1.0 3.4 1.8 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257159-150265078 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.9;retina: 29.4;seminal vesicle: 16.5;skeletal muscle: 24.1" "Group enriched" "Detected in some" 16 "Cardiomyocytes: 44.5;Melanocytes: 50.6;Muller glia cells: 123.0" "Group enriched" "Detected in many" 7 "glioma: 4.9;melanoma: 23.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "AF22: 28.7;AN3-CA: 17.0;NTERA-2: 22.3;SK-MEL-30: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.1 0.3 4.6 0.2 5.2 0.9 0.3 1.4 6.8 0.1 1.7 10.8 0.1 0.3 0.1 0.5 1.6 1.3 0.7 4.4 6.4 4.1 0.3 6.3 0.2 0.2 11.3 3.2 1.4 0.3 0.8 0.1 0.3 4.4 3.2 0.7 29.4 0.6 16.5 24.1 3.7 0.6 0.5 20.9 0.3 0.8 0.5 2.7 0.1 0.9 0.1 0.1 0.2 0.1 2.8 2.2 2.1 2.0 0.2 1.6 0.2 0.2 0.0 28.7 17.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.1 22.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.1 57.1 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.1 0.1 0.1 0.0 0.0 0.9 1.3 1.6 2.0 0.6 2.0 1.0 1.2 0.2 2.8 1.2 1.3 2.1 0.2 0.5 2.2 0.0 0.2 4.6 5.2 1.4 4.7 6.4 4.1 11.3 3.2 4.4 2.7 3.0 0.3 0.0 0.2 1.9 1.4 44.5 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 50.6 0.0 0.0 123.0 1.2 0.0 3.2 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.4 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463852-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Lyase "Disease mutation, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.1;stomach 1: 171.5" "Cell type enhanced" "Detected in many" 14 "Enterocytes: 870.3;Erythroid cells: 2055.8;Muller glia cells: 1176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 20.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 33.8;HEK 293: 142.4;THP-1: 59.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001550, CAB010102" Enhanced NA Yes 790000000 "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 1.6 2.2 24.4 21.5 32.6 32.4 6.9 4.3 23.2 1.3 108.1 28.9 42.0 46.9 0.9 2.2 5.6 0.9 33.0 4.3 29.1 14.5 53.5 43.0 10.2 1.3 49.0 14.2 0.5 9.1 3.1 2.0 3.5 65.0 0.8 105.6 7.0 14.0 54.2 9.2 13.3 7.6 6.0 27.5 2.5 171.5 5.1 58.3 0.0 3.8 2.4 1.1 1.0 1.4 1.9 8.0 20.3 8.2 0.0 4.4 17.5 0.5 0.3 1.6 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 2.0 0.1 0.0 1.2 0.0 0.0 33.8 4.9 1.7 0.0 0.0 142.4 4.4 2.5 0.0 0.0 3.1 0.6 0.0 8.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.4 11.2 0.0 2.7 0.1 0.0 0.5 1.1 0.0 0.0 0.7 0.0 0.0 1.3 0.0 59.7 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 20.3 3.1 4.4 0.1 8.2 4.4 0.6 0.0 0.4 8.0 1.9 0.0 0.0 6.8 0.0 7.1 0.8 0.0 17.5 24.4 32.6 4.3 23.2 29.1 14.5 49.0 14.2 65.0 58.3 14.9 56.8 27.3 1.0 80.5 23.5 18.5 400.0 0.0 1.2 153.5 60.9 10.7 295.1 50.5 65.5 14.6 870.3 2055.8 9.9 311.4 6.4 1.1 16.1 101.2 34.8 12.7 29.2 1.8 8.2 179.8 3.1 46.0 70.9 1.0 94.2 1176.2 10.3 374.2 2.1 304.9 61.5 0.0 7.3 1.7 2.3 97.6 14.3 5.7 229.3 0.3 CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "skeletal muscle: 347.5" "Cell type enriched" "Detected in some" 14 "Erythroid cells: 280.4" "Group enriched" "Detected in many" 7 "glioma: 23.1;prostate cancer: 9.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 9 "HEL: 23.8;RH-30: 40.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB004967, HPA021775, HPA026700" Enhanced NA NA 31000000 "CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991" "prognostic favorable (4.24e-6)" "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (8.43e-3)" "unprognostic (3.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-1)" "unprognostic (4.71e-2)" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.18e-1)" "unprognostic (9.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" 18.0 0.4 0.2 0.1 0.2 0.5 0.6 0.2 0.1 0.5 0.3 0.0 0.1 0.1 0.6 29.0 9.5 1.0 0.2 1.3 0.2 0.1 0.2 0.2 4.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 6.6 0.0 0.0 5.5 0.2 347.5 0.3 0.4 1.4 0.1 0.1 0.3 0.5 0.0 0.0 0.3 14.1 3.4 0.7 0.5 0.5 1.8 0.0 0.0 0.0 0.8 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 23.8 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 40.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 3.0 3.4 0.0 0.9 0.5 0.0 0.8 7.6 0.0 0.0 0.0 5.9 0.6 0.0 0.7 20.2 0.0 0.7 280.4 0.2 0.0 0.6 0.5 0.0 0.0 0.4 0.0 0.0 1.8 0.3 4.7 0.3 0.0 0.0 0.0 0.3 16.0 0.2 1.7 0.0 0.5 1.4 0.0 0.1 0.5 0.9 0.9 1.4 0.0 0.6 0.3 CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149936-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.7" "Cell type enriched" "Detected in many" 43 "Paneth cells: 2128.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 50.1" "Cell type enriched" "Detected in some" 7 "neutrophil: 37.0" "Lineage enriched" "Detected in single" 370 "granulocytes: 37.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.5;NTERA-2: 3.4;OE19: 3.9;RPTEC TERT1: 1.9;SuSa: 2.6" "Region enriched" "Detected in all" 5 "cerebellum: 336.9" "Low region specificity" "Detected in many" "HPA011089, HPA017258" Enhanced NA NA 190000 "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" 32.2 0.9 3.4 9.8 4.4 5.7 46.4 50.1 11.8 2.3 81.7 2.0 31.5 1.4 2.3 17.4 0.9 1.7 12.2 8.8 4.7 2.6 12.0 0.3 33.3 2.4 3.5 5.2 1.9 9.5 3.3 5.1 3.2 3.0 2.4 54.9 20.3 4.8 24.0 10.0 1.0 3.2 1.1 2.1 4.9 2.5 1.2 0.3 0.2 23.1 5.0 0.2 1.7 7.9 0.0 0.0 37.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.5 0.8 0.1 0.0 0.3 0.0 0.0 0.3 1.3 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 3.9 0.0 0.0 0.2 1.3 1.9 0.0 0.7 0.3 0.2 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.7 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.0 0.0 3.4 4.4 50.1 11.8 4.7 2.6 3.5 5.2 3.0 0.3 0.0 3.7 0.0 0.2 1.3 0.0 9.2 0.0 1.4 1.2 14.0 0.0 0.0 28.2 3.1 0.2 15.8 49.7 0.0 0.2 0.0 1.5 0.1 11.5 0.0 0.5 0.0 18.6 1.8 0.0 0.0 0.6 0.8 0.0 0.0 27.9 0.0 0.1 2128.8 0.0 18.6 0.0 6.5 17.9 0.0 0.0 1.0 0.0 0.0 32.8 0.3 CA5A "CA5, CAV, CAVA" ENSG00000174990 "Carbonic anhydrase 5A" P35218 16 87881546-87936529 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 26.4" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 35.0" "Cancer enriched" "Detected in single" 26 "liver cancer: 2.0" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Hep G2: 6.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "unprognostic (1.91e-1)" "unprognostic (8.64e-3)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (2.49e-2)" "unprognostic (2.96e-1)" "unprognostic (8.39e-3)" "unprognostic (3.50e-3)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (6.55e-2)" "unprognostic (4.23e-2)" "unprognostic (7.99e-3)" "unprognostic (1.77e-1)" "unprognostic (5.03e-3)" "unprognostic (3.37e-2)" "unprognostic (2.76e-2)" 0.0 0.0 0.3 0.8 0.4 2.7 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.3 0.0 26.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.3 0.8 0.0 0.3 0.1 0.0 0.0 0.0 1.9 1.6 4.7 1.1 1.9 1.1 0.4 0.2 0.3 0.3 0.7 0.1 0.0 0.5 0.4 0.1 0.0 0.1 0.5 0.6 0.6 0.2 0.2 0.3 0.6 0.2 0.3 0.1 0.4 0.3 0.4 1.1 6.8 0.0 0.4 1.7 0.8 0.0 0.2 0.4 0.5 0.3 0.5 0.4 1.6 0.1 0.5 0.2 1.0 0.5 0.3 0.6 0.4 0.4 0.2 0.2 0.6 0.4 0.2 0.2 0.3 0.1 0.5 0.6 0.3 0.4 0.8 0.2 0.5 0.3 0.7 0.4 0.4 0.6 0.9 0.4 4.1 1.1 1.0 0.8 0.7 0.8 0.9 0.8 0.6 0.3 1.9 1.1 1.1 4.7 1.9 0.7 1.6 0.5 0.4 0.0 4.3 0.0 2.5 0.3 1.7 1.4 0.0 2.7 2.3 1.8 3.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.4 1.4 5.8 35.0 0.1 3.2 0.0 1.3 0.6 0.8 0.3 1.9 0.0 0.0 0.0 0.9 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.3 0.6 0.3 0.2 0.0 0.0 1.3 CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788409 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Muller glia cells: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.7;fHDF/TERT166: 17.9;hTERT-HME1: 23.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012618 Uncertain Supported Mitochondria NA NA Mitochondria "HPA012618: AB_1846000" "unprognostic (1.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-2)" "unprognostic (4.59e-5)" "unprognostic (2.50e-1)" "unprognostic (6.89e-4)" "unprognostic (4.11e-1)" "unprognostic (3.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.66e-6)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-2)" "unprognostic (3.08e-1)" 9.3 4.6 10.6 4.9 11.1 4.1 10.2 3.1 7.8 28.7 3.6 11.5 1.4 2.2 9.8 3.7 8.1 9.5 9.1 6.5 9.9 8.2 10.3 7.8 7.3 8.8 12.2 6.7 15.2 4.4 16.8 4.4 3.9 13.1 6.2 4.7 29.5 8.3 6.2 2.0 7.5 4.1 9.4 7.1 5.3 5.4 23.0 8.1 2.3 8.9 10.9 11.6 6.3 9.4 4.3 3.5 2.7 3.6 7.9 13.3 7.0 2.7 1.7 2.0 3.2 5.9 15.7 1.1 2.9 3.7 2.2 3.2 0.8 1.9 0.8 3.1 17.9 4.2 3.0 6.9 3.3 3.9 0.7 3.3 1.5 2.1 0.7 5.8 1.9 3.4 3.6 3.6 2.9 23.5 3.9 3.2 2.3 0.8 2.1 10.3 1.5 1.6 1.5 0.8 0.5 12.5 0.9 1.4 1.4 3.3 2.0 1.7 3.7 4.1 1.5 2.6 2.4 2.1 1.9 4.3 2.6 1.7 13.9 1.6 1.5 1.5 0.9 2.9 3.9 4.8 2.7 3.0 0.3 13.1 3.6 11.4 3.6 13.3 12.3 3.5 4.3 9.8 8.3 1.7 7.9 2.3 0.5 10.0 7.0 10.6 11.1 3.1 7.8 9.9 8.2 12.2 6.7 13.1 8.1 0.0 9.3 7.2 5.3 3.8 8.9 1.6 0.0 17.4 10.3 1.8 15.7 1.4 1.7 3.6 0.9 10.7 0.5 23.3 3.5 1.2 7.2 9.7 2.3 2.4 1.7 1.6 2.9 3.7 7.8 1.3 7.2 9.6 3.3 1.0 2.4 37.2 3.8 0.9 4.9 2.2 8.0 6.5 7.2 3.3 5.9 4.0 1.6 15.9 1.7 6.3 CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, Predicted secreted proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "salivary gland: 1237.9" "Cell type enriched" "Detected in single" 404 "Melanocytes: 170.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 15.4" "Lineage enriched" "Detected in many" 10 "T-cells: 15.4" "Cell line enhanced" "Detected in many" "Daudi: 5.5;U-2197: 4.8" "Not detected" "Not detected" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" NA NA 34000000 "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" 0.3 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1237.9 0.0 0.1 24.9 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.6 0.4 1.5 0.3 0.4 15.4 1.6 1.2 0.5 0.9 1.8 0.3 0.3 1.4 0.9 0.1 0.2 0.6 1.0 1.6 5.5 0.6 0.5 1.3 1.6 0.4 0.1 0.8 0.6 0.6 0.8 2.0 1.1 0.4 2.0 2.0 0.0 1.0 0.9 0.1 1.2 0.7 1.4 0.7 3.4 0.1 0.8 1.0 1.5 1.1 1.0 0.8 1.5 0.6 0.3 0.2 1.0 1.0 0.9 0.2 0.9 0.3 0.9 1.5 0.8 0.3 2.8 1.5 4.8 1.2 1.5 0.5 1.7 0.6 1.8 1.4 1.1 0.3 0.2 0.4 0.2 0.4 0.3 0.8 2.8 0.0 0.6 5.6 15.4 1.5 0.4 0.2 0.4 0.3 1.6 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 170.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CA7 ENSG00000168748 "Carbonic anhydrase 7" P43166 16 66844379-66854153 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 37.2" "Cell type enriched" "Detected in some" 58 "Paneth cells: 2512.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;HAP1: 1.8;NTERA-2: 1.6;REH: 3.4;SCLC-21H: 2.7;THP-1: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047237 Uncertain NA NA "HPA047237: AB_2679994" "unprognostic (8.77e-4)" "unprognostic (5.23e-4)" "unprognostic (1.57e-1)" "unprognostic (1.96e-2)" "unprognostic (2.19e-1)" "unprognostic (2.16e-2)" "unprognostic (7.90e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "unprognostic (9.62e-2)" "unprognostic (1.69e-2)" "unprognostic (7.12e-3)" "unprognostic (8.47e-2)" "unprognostic (5.20e-1)" "unprognostic (1.90e-2)" "unprognostic (6.46e-2)" 0.2 0.2 3.2 0.4 7.5 0.2 0.2 3.9 7.7 0.2 37.2 0.3 0.0 4.8 0.3 0.9 0.3 0.2 0.2 0.2 6.3 0.5 0.2 0.2 0.2 0.2 0.7 2.9 0.2 0.2 0.2 0.0 0.2 1.8 0.2 32.0 0.0 1.1 0.4 0.2 0.2 22.8 1.0 0.1 0.2 0.2 0.5 1.3 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.9 3.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 7.5 3.9 7.7 6.3 0.5 0.7 2.9 1.8 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 2512.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 25.5 0.0 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673856-35681159 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 70.4;pancreas: 47.4;stomach 1: 70.8" "Cell type enhanced" "Detected in some" 25 "Cholangiocytes: 53.5;Early spermatids: 178.0;Exocrine glandular cells: 46.4;Pancreatic endocrine cells: 33.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 7.3" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 40.0;HDLM-2: 20.8;hTERT-RPE1: 25.5;U-87 MG: 83.9" "Region enriched" "Detected in some" 4 "cerebellum: 13.8" "Low region specificity" "Detected in some" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 1.0 0.1 0.0 0.1 0.3 0.0 0.0 7.3 0.7 0.5 7.2 0.1 0.2 6.7 0.1 1.5 0.3 0.1 70.4 0.7 0.0 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.7 47.4 0.0 0.2 0.7 0.4 0.2 0.0 0.1 0.0 0.0 0.0 2.6 8.0 0.0 0.4 0.0 70.8 1.4 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 1.1 0.0 0.0 0.4 0.1 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.2 0.3 20.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 25.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 83.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.3 7.3 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.3 53.5 0.0 0.0 0.0 0.0 0.0 0.0 27.8 178.0 0.0 0.0 0.0 46.4 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 12.2 1.4 0.0 0.0 1.0 0.1 1.5 33.9 0.0 0.7 0.0 0.0 0.0 0.4 0.9 2.7 2.8 0.2 0.0 0.2 0.3 CBS HIP4 ENSG00000160200 Cystathionine-beta-synthase P35520 21 43053191-43076943 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Allosteric enzyme, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 55.7;pancreas: 43.0" "Cell type enhanced" "Detected in some" 13 "Cardiomyocytes: 3.5;Hepatocytes: 2.6;Melanocytes: 5.0;Smooth muscle cells: 2.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 84 "neutrophil: 8.3" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.3" "Cell line enhanced" "Detected in many" "BEWO: 40.8;HAP1: 38.9;HHSteC: 52.7;MCF7: 45.1;RPMI-8226: 43.1" HPA001223 Supported Approved Nucleoli,Vesicles NA NA Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (4.86e-2)" "unprognostic (1.48e-2)" "unprognostic (6.81e-2)" "unprognostic (1.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.68e-4)" "unprognostic (3.62e-1)" "unprognostic (6.76e-3)" "unprognostic (1.06e-1)" "unprognostic (6.50e-2)" "unprognostic (2.13e-1)" "unprognostic (1.61e-2)" "unprognostic (6.73e-3)" "unprognostic (2.62e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" 1.3 1.5 6.5 2.4 5.1 0.4 1.0 12.3 6.7 4.8 1.3 2.0 0.8 1.6 0.9 0.8 0.8 2.0 2.1 2.0 5.6 5.5 1.3 55.7 1.7 1.4 4.8 2.8 13.9 43.0 0.3 1.4 1.4 2.3 4.0 0.7 2.8 9.3 3.4 0.8 0.6 2.9 1.4 3.7 0.8 2.7 2.2 3.3 0.8 5.0 0.8 0.9 2.6 0.8 0.0 0.0 8.3 0.0 0.0 0.0 0.0 6.4 3.9 5.1 20.0 11.5 7.4 40.8 8.0 2.0 3.3 3.4 12.0 0.3 0.0 4.3 15.0 0.0 0.4 38.9 2.8 0.6 0.0 4.9 2.7 15.6 14.4 52.7 1.6 3.8 4.5 0.4 3.6 3.2 3.0 8.8 18.9 30.1 22.7 2.5 45.1 2.8 0.0 4.8 14.6 6.8 0.0 0.0 43.1 0.1 3.6 10.6 15.6 17.4 1.0 7.5 4.3 6.2 20.4 1.2 0.2 10.0 0.1 0.8 7.9 6.3 9.0 3.7 2.4 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 6.5 5.1 12.3 5.2 5.6 5.5 4.8 2.8 2.3 3.3 0.0 0.3 0.0 0.0 0.3 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.2 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 5.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 CBSL ENSG00000274276 "Cystathionine-beta-synthase like" P0DN79 21 6444869-6468040 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.5;liver: 21.2;pancreas: 18.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Cell type enriched" "Detected in single" 47 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "AN3-CA: 36.5;NTERA-2: 67.6;SH-SY5Y: 21.6;U-266/70: 21.3" HPA001223 Supported Approved Nucleoli,Vesicles NA NA 190000 Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (2.39e-1)" "unprognostic (1.54e-2)" "unprognostic (1.15e-1)" "unprognostic (4.78e-3)" "unprognostic (6.49e-2)" "unprognostic (1.42e-2)" "unprognostic (1.28e-2)" "unprognostic (6.62e-3)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (7.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (3.17e-3)" "unprognostic (8.44e-2)" "unprognostic (2.46e-1)" "unprognostic (3.61e-1)" 0.0 0.0 0.0 0.0 0.0 11.5 1.8 0.0 0.4 0.0 0.0 0.0 0.3 0.0 1.0 0.0 21.2 0.0 0.0 1.6 18.5 0.0 0.0 1.8 0.0 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 5.0 0.0 0.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 12.2 36.5 0.0 0.0 0.4 7.6 4.4 2.8 8.5 0.1 4.9 0.0 0.0 0.0 4.7 3.2 0.0 3.9 1.7 0.0 9.6 0.0 0.0 0.0 0.2 0.0 5.2 4.2 14.2 0.0 7.1 0.0 0.0 0.8 0.2 16.9 0.1 0.0 5.7 0.6 67.6 0.0 0.0 0.0 0.0 0.0 11.0 0.0 14.1 21.6 0.0 1.1 14.7 0.0 0.0 0.0 0.0 0.7 0.0 4.7 1.5 21.3 7.8 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956519 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 53.0;salivary gland: 39.9;skeletal muscle: 52.4" "Cell type enhanced" "Detected in many" 10 "Distal tubular cells: 29.9;Exocrine glandular cells: 24.3;Pancreatic endocrine cells: 16.5;Urothelial cells: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.8" "Group enriched" "Detected in many" 6 "B-cells: 1.8;monocytes: 1.1;T-cells: 1.3" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.1;HHSteC: 26.8;hTCEpi: 42.4;SK-MEL-30: 30.0;U-266/70: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042708, HPA043505" Approved Approved Mitochondria NA NA Mitochondria "HPA042708: AB_2678125, HPA043505: AB_2678518" "unprognostic (6.04e-3)" "unprognostic (2.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.84e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-2)" "unprognostic (5.59e-2)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.23e-7)" "unprognostic (1.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-2)" "unprognostic (3.91e-2)" 6.0 1.0 2.6 1.5 2.1 1.7 1.0 1.7 5.6 1.1 1.9 0.3 1.1 1.9 1.1 1.8 18.6 1.5 5.7 2.2 2.6 4.8 3.1 14.1 1.5 1.1 2.6 2.2 11.3 53.0 0.9 1.3 1.1 6.2 1.5 1.1 0.2 39.9 1.3 52.4 1.3 1.5 1.1 5.3 1.1 11.2 0.9 1.0 0.0 1.7 4.7 4.6 2.7 2.7 1.8 0.1 0.2 1.1 0.0 1.3 0.2 2.8 1.9 0.5 8.8 1.4 1.0 3.6 17.0 35.1 1.8 5.0 4.7 0.7 0.8 1.3 1.5 5.6 1.9 3.8 1.4 1.3 3.2 0.7 0.7 0.5 0.0 26.8 2.2 0.0 12.0 42.4 5.5 7.7 0.5 1.7 19.6 2.3 4.0 1.5 1.6 1.6 0.0 1.6 9.7 6.6 1.4 0.0 3.8 0.9 1.1 1.7 2.5 0.5 3.0 30.0 1.1 1.1 16.0 0.5 0.3 5.3 0.4 3.0 26.3 5.6 3.4 1.6 3.1 4.0 0.0 0.4 0.0 1.3 0.4 0.0 1.8 0.2 0.8 0.1 0.0 0.0 1.0 0.2 0.0 1.1 0.0 0.0 0.2 2.6 2.1 1.7 5.6 2.6 4.8 2.6 2.2 6.2 1.0 0.0 1.3 1.5 3.4 2.5 2.3 3.5 2.5 0.0 1.2 0.0 2.0 0.2 29.9 7.5 0.1 0.5 2.8 0.0 24.3 0.2 0.5 5.1 0.0 0.4 0.3 0.0 3.4 1.8 0.8 0.0 0.3 0.4 5.0 1.8 1.5 0.3 16.5 0.3 0.0 0.1 0.4 0.0 0.5 1.4 0.7 3.8 2.9 0.0 1.5 11.8 CHAC2 GCG1 ENSG00000143942 "ChaC cation transport regulator homolog 2" Q8WUX2 2 53767792-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Spermatocytes: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA Cytosol "HPA049235: AB_2680686" "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 7.2 8.6 6.5 7.1 6.2 9.3 3.6 4.3 4.4 2.6 6.8 2.1 7.7 11.4 2.4 4.4 8.4 1.8 5.3 10.3 6.2 6.1 8.3 9.8 3.4 9.6 5.0 4.2 1.8 4.8 1.5 6.7 1.7 6.9 2.8 6.1 2.8 4.1 4.6 9.8 2.0 9.0 3.5 4.8 10.2 7.0 16.4 3.7 9.5 3.7 4.2 9.8 5.7 5.1 6.6 2.5 1.8 0.9 1.4 6.7 3.0 19.1 6.4 6.8 6.0 3.4 1.7 1.4 8.8 1.8 6.3 7.5 4.4 4.9 16.3 12.9 3.8 9.5 6.9 15.4 10.5 11.1 34.3 13.4 12.9 8.6 7.2 5.2 15.2 5.9 2.1 3.1 11.7 8.9 1.7 12.3 11.3 13.2 9.6 8.3 6.2 18.0 12.7 8.8 8.3 11.5 13.8 14.5 16.5 8.7 5.2 8.5 2.4 10.2 7.6 4.0 4.3 4.6 6.0 5.4 3.7 13.3 14.2 14.2 9.6 12.3 13.9 5.0 19.2 5.1 1.8 0.5 1.1 5.2 0.9 5.5 6.6 5.7 5.8 1.1 5.4 6.7 6.1 1.4 1.4 0.7 2.5 5.1 3.0 6.5 6.2 4.3 4.4 6.2 6.1 5.0 4.2 6.9 3.7 0.0 1.4 11.5 2.8 3.1 0.8 2.8 5.1 1.4 2.3 1.8 0.0 1.7 10.0 5.8 5.3 3.7 2.6 0.0 7.1 0.7 1.6 2.9 1.1 7.5 6.6 1.6 0.0 2.5 1.0 1.7 2.6 2.8 3.3 8.2 3.4 3.3 6.4 0.0 3.9 5.6 5.5 0.0 3.4 26.1 5.1 3.0 0.3 6.9 9.2 3.9 CLYBL CLB ENSG00000125246 "Citrate lyase beta like" Q8N0X4 13 99606669-99897134 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.7" "Cell type enhanced" "Detected in many" 10 "Distal tubular cells: 117.7;Hepatocytes: 75.9;Proximal tubular cells: 93.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 29.2;SCLC-21H: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" 4.2 11.6 6.2 10.4 9.4 2.6 6.0 6.7 6.4 4.6 11.2 3.8 4.8 13.6 5.2 7.6 6.4 4.7 8.3 12.3 5.1 6.3 35.0 57.7 4.7 9.6 7.9 8.6 3.5 15.0 6.1 5.7 2.2 12.5 4.2 12.3 8.9 8.7 5.5 22.2 5.7 12.5 8.6 4.5 5.5 4.8 10.7 4.3 4.6 7.0 13.3 8.2 4.9 4.4 11.0 7.5 1.2 6.7 9.2 16.7 5.5 0.2 1.2 9.0 4.0 4.2 3.9 1.9 0.4 0.8 0.7 1.4 0.2 6.6 1.5 2.6 0.5 1.7 2.0 0.8 1.5 1.0 7.9 1.3 9.9 2.4 6.1 2.9 5.3 0.7 2.1 4.4 0.1 3.4 0.9 1.1 8.3 1.4 5.2 0.8 2.2 2.4 7.4 5.8 29.2 1.8 3.1 0.3 3.6 8.8 0.6 28.8 4.4 1.8 2.0 1.7 3.3 4.3 6.9 0.1 0.4 1.0 0.7 1.4 12.1 2.4 0.3 6.1 7.8 1.2 1.2 3.3 0.3 7.5 6.7 9.0 10.9 13.3 10.6 6.7 11.0 10.3 12.1 0.5 9.2 3.2 7.5 16.7 5.5 6.2 9.4 6.7 6.4 5.1 6.3 7.9 8.6 12.5 4.3 6.0 5.3 4.4 8.9 4.8 1.8 30.3 20.4 4.0 11.4 14.0 2.0 11.2 117.7 9.6 1.2 6.3 18.6 0.0 7.0 2.5 2.6 3.4 5.8 75.9 6.9 0.0 1.2 6.2 7.5 4.0 2.0 7.7 15.1 4.6 8.4 4.5 3.8 14.0 3.9 93.6 4.3 0.0 9.2 3.1 9.1 5.5 6.2 6.9 16.4 5.1 CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180909 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "ASC diff: 39.2;T-47d: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039487 Approved "Intracellular and membrane" NA NA "HPA039487: AB_10672776" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favorable (6.33e-4)" "prognostic favorable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favorable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favorable (6.81e-6)" 30.3 11.4 23.4 12.4 17.8 24.8 26.0 26.4 20.8 17.8 13.1 23.5 24.7 12.4 27.7 39.4 12.3 16.5 14.6 9.9 19.3 10.2 14.9 39.5 12.7 12.5 18.3 22.4 24.6 15.3 16.4 18.4 9.5 17.6 24.8 12.1 19.5 23.2 19.6 12.9 41.9 12.0 14.8 18.9 16.5 12.4 18.5 18.9 12.1 16.0 9.9 10.2 10.5 16.2 2.1 2.2 16.3 2.0 1.5 3.0 0.4 1.6 3.0 7.2 3.0 39.2 16.2 2.6 6.4 1.4 2.7 2.3 1.8 3.9 2.1 4.9 3.4 0.9 5.6 3.2 5.0 1.6 2.8 3.9 3.4 7.3 3.8 3.5 1.4 2.2 19.8 6.3 4.1 5.1 14.1 2.5 4.6 3.6 19.4 2.6 13.6 0.7 4.0 1.4 0.8 2.8 2.8 0.4 4.9 3.6 4.2 3.7 2.8 6.3 9.1 2.3 4.7 23.8 2.8 5.6 8.0 1.6 2.3 1.8 5.5 1.3 1.1 6.7 3.6 3.2 3.5 2.0 2.2 1.3 1.1 0.8 1.2 1.9 0.8 0.9 2.1 2.5 1.4 16.3 1.5 1.2 2.2 3.0 0.4 23.4 17.8 26.4 20.8 19.3 10.2 18.3 22.4 17.6 18.9 3.0 15.8 22.3 24.0 14.7 28.3 7.8 12.7 14.7 11.4 22.7 15.7 10.2 3.3 9.7 0.2 18.9 19.5 0.0 7.8 5.7 17.7 30.0 9.2 34.8 7.2 25.4 13.8 12.3 11.0 1.1 25.0 11.5 13.5 11.8 12.9 30.0 8.0 28.1 29.0 2.4 27.8 38.8 21.7 50.6 58.8 15.9 7.4 12.5 11.5 20.2 CTH ENSG00000116761 "Cystathionine gamma-lyase" P32929 1 70411218-70439851 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Calmodulin-binding, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 104.5" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 130.7" "Group enriched" "Detected in all" 5 "liver cancer: 30.0;testis cancer: 8.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.5;T-cells: 6.4" "Cell line enhanced" "Detected in many" "HHSteC: 20.2;Karpas-707: 31.3;SK-MEL-30: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021591, HPA023300" Enhanced NA NA 25000 "HPA021591: AB_1847321, HPA023300: AB_1847322" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" "unprognostic (7.66e-2)" "unprognostic (2.45e-3)" "prognostic favorable (8.69e-4)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-3)" "unprognostic (5.05e-3)" "unprognostic (3.25e-2)" "unprognostic (1.03e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.26e-1)" 2.2 8.3 2.3 1.0 3.2 2.2 2.0 3.7 3.6 1.9 3.3 2.2 1.8 3.3 1.7 1.4 2.7 2.3 1.5 1.6 2.1 2.7 8.2 104.5 2.2 1.0 2.4 2.2 18.3 11.6 1.5 1.7 1.0 3.2 2.9 4.1 11.2 4.8 2.8 2.1 1.0 3.2 1.2 2.4 0.8 3.7 5.4 1.3 0.0 11.4 1.2 1.5 2.7 1.2 4.5 1.3 1.1 0.6 0.6 6.4 1.1 5.1 0.7 3.5 4.9 4.3 2.4 7.8 2.1 1.9 1.8 7.8 1.4 3.2 2.8 1.6 1.5 4.6 2.4 13.5 1.4 3.6 8.6 3.0 3.3 2.6 4.4 20.2 3.7 0.8 3.7 12.2 3.7 4.3 0.7 1.6 5.6 6.5 31.3 1.1 1.4 1.3 0.8 3.6 1.9 2.7 1.3 1.9 7.8 3.6 0.0 1.9 1.6 3.2 3.8 40.8 6.9 1.3 2.1 0.5 0.6 4.0 2.8 1.9 12.1 7.1 1.5 4.8 7.7 1.4 1.1 0.6 0.2 2.5 0.4 4.6 4.5 2.3 3.5 1.0 2.9 6.4 3.1 0.9 0.6 0.5 1.3 0.7 1.1 2.3 3.2 3.7 3.6 2.1 2.7 2.4 2.2 3.2 1.3 6.0 3.5 5.6 6.2 2.3 6.8 1.6 5.1 0.0 1.2 5.2 9.8 0.6 10.0 1.6 14.9 2.0 11.9 0.0 3.5 1.3 2.8 5.2 0.0 130.7 1.0 0.0 2.9 4.3 2.9 3.4 1.1 1.3 18.6 0.0 5.9 4.3 6.4 11.0 3.9 22.0 10.1 0.0 5.5 1.6 0.5 1.8 0.7 4.3 4.3 2.8 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565457 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 90.1;kidney: 68.1" "Group enriched" "Detected in many" 5 "Intestinal endocrine cells: 394.4;Proximal tubular cells: 366.2;Rod photoreceptor cells: 456.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "midbrain: 7.9;pons and medulla: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 17.2;Hep G2: 15.1;OE19: 26.4;SCLC-21H: 43.6;SH-SY5Y: 45.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "midbrain: 90.4;pons and medulla: 40.7" HPA017742 Enhanced Approved "Actin filaments" NA NA 380000 "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.3 10.9 0.3 3.0 0.7 0.0 0.3 0.3 0.4 0.3 36.7 0.4 0.3 33.5 0.3 1.8 0.3 0.0 0.7 0.3 0.3 1.3 68.1 11.7 0.7 0.3 7.9 0.3 0.4 9.8 0.0 0.3 0.3 3.4 0.4 8.1 0.4 0.3 0.3 0.3 0.1 90.1 0.3 0.3 0.3 4.3 0.6 0.5 0.3 0.3 0.4 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.4 0.0 0.0 0.0 0.2 0.4 0.0 43.6 45.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.3 0.4 0.3 1.3 7.9 0.3 3.4 0.5 0.0 9.8 0.8 0.0 0.0 81.1 0.4 5.1 0.0 1.2 3.5 39.3 0.0 21.6 0.0 3.6 0.0 72.8 0.0 0.7 0.1 0.0 0.4 0.0 58.7 0.1 3.2 394.4 1.3 1.3 4.3 0.0 0.0 0.0 0.0 30.4 24.1 0.2 26.6 0.0 366.2 456.4 0.0 0.0 3.6 0.4 0.0 0.1 0.0 46.0 0.0 DDT DDCT ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23980469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.8;liver: 58.4" "Cell type enriched" "Detected in all" 5 "Hepatocytes: 4710.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 68.5" "HPA049871, HPA074115" Enhanced Approved Mitochondria NA NA Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" 9.7 6.6 5.4 3.4 4.8 8.8 4.5 2.1 4.4 3.0 9.8 11.8 2.7 4.3 5.8 2.8 1.4 7.7 4.2 4.0 11.3 58.4 3.2 2.9 5.4 4.1 14.4 1.3 1.8 2.5 5.8 6.4 7.1 4.4 10.4 3.7 11.6 2.0 4.6 3.2 8.2 1.2 3.7 2.7 4.3 3.2 30.4 52.8 27.8 38.0 23.8 29.0 28.6 27.1 11.6 4.0 9.4 7.7 6.8 24.5 7.9 5.3 6.9 7.2 10.2 7.9 26.0 7.4 4.1 10.2 22.5 10.0 9.8 4.5 11.0 68.5 15.6 15.8 22.2 7.8 34.2 15.7 6.8 7.5 6.9 6.1 8.0 7.4 4.1 14.1 10.5 6.9 13.3 7.5 31.0 12.1 24.0 35.0 16.5 7.5 37.1 12.3 10.0 13.7 13.2 16.3 30.9 23.2 5.7 7.8 10.8 8.5 7.2 16.0 7.3 8.2 32.4 10.7 16.3 14.1 12.7 13.8 20.7 38.0 27.8 19.9 32.4 20.3 30.4 24.1 21.1 35.7 28.4 21.9 21.3 24.2 23.8 29.6 52.8 29.0 28.6 77.4 62.3 170.5 177.4 123.4 46.7 20.4 580.9 78.9 76.2 230.3 84.4 209.3 608.5 198.5 156.1 122.0 650.8 116.8 322.3 247.0 92.9 222.4 128.0 4710.9 242.3 41.3 249.4 161.4 217.6 261.8 108.4 147.1 150.1 220.0 322.2 63.3 238.6 309.5 104.0 969.7 70.4 77.6 140.0 72.1 40.3 164.4 250.7 154.1 488.9 247.4 DERA "CGI-26, DEOC" ENSG00000023697 "Deoxyribose-phosphate aldolase" Q9Y315 12 15911172-16037282 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055897 Supported Nucleoplasm NA NA 180000 Nucleoplasm "HPA055897: AB_2682963" "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (1.06e-2)" "unprognostic (7.26e-2)" "unprognostic (8.12e-2)" "unprognostic (7.74e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (8.74e-2)" "unprognostic (2.17e-2)" "prognostic favorable (3.64e-5)" "unprognostic (3.66e-2)" 20.3 12.0 10.5 10.8 10.8 7.5 11.5 5.2 7.7 11.3 30.3 11.4 12.7 20.2 21.5 14.7 20.0 8.2 11.1 11.7 10.1 9.1 40.9 51.5 13.6 14.1 12.5 6.5 5.8 16.9 6.6 27.5 12.3 11.3 9.2 21.2 11.0 11.4 11.3 15.3 12.4 46.7 10.4 14.6 14.6 10.5 5.5 11.0 13.8 26.6 16.7 14.3 10.1 13.1 12.4 30.2 14.1 28.2 17.1 14.9 15.7 19.0 15.8 12.4 10.9 8.4 19.2 25.4 11.1 10.5 15.2 19.5 19.0 35.4 13.0 9.9 14.2 13.7 13.5 13.4 14.3 27.0 21.7 7.8 11.5 7.9 17.9 12.1 12.1 7.8 12.8 16.6 12.4 25.5 12.9 21.9 11.1 1.6 4.0 27.6 7.0 9.0 10.1 27.0 10.7 7.8 13.8 27.2 8.1 38.1 6.9 9.0 15.3 21.0 7.0 21.9 51.1 37.9 15.2 21.6 16.2 10.7 7.4 11.9 4.3 6.3 22.4 20.8 12.2 11.9 5.4 24.4 14.1 7.2 27.1 7.9 12.4 7.8 7.7 30.2 11.4 8.6 6.9 6.5 17.1 28.2 16.5 14.9 15.7 10.5 10.8 5.2 7.7 10.1 9.1 12.5 6.5 11.3 11.0 41.7 25.0 18.6 24.3 26.1 5.0 11.4 22.9 21.4 22.7 12.2 13.7 54.5 92.9 55.2 33.8 25.2 49.7 0.0 52.2 57.8 21.3 17.5 8.1 44.5 53.2 3.2 25.4 30.7 32.6 3.0 22.7 32.0 69.2 55.9 43.0 20.9 60.6 45.0 28.7 104.3 25.2 6.5 18.6 5.0 14.7 22.6 59.6 10.0 39.9 24.7 DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.9" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 1: 26.8;Collecting duct cells: 27.9;Cytotrophoblasts: 25.8;Hofbauer cells: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 57.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol NA NA Cytosol "HPA041423: AB_10795540, HPA052932: AB_2681991" "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (4.28e-4)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (9.48e-5)" "unprognostic (3.56e-1)" "prognostic favorable (7.28e-4)" "unprognostic (2.30e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.77e-15)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.75e-2)" "unprognostic (2.57e-3)" 12.5 18.7 23.4 15.9 23.1 10.7 9.3 27.3 22.6 14.6 16.7 18.1 16.0 13.8 16.8 13.1 16.0 21.9 12.5 63.9 18.8 16.6 20.1 13.1 13.7 11.2 20.1 19.2 13.4 9.3 29.3 14.2 9.2 19.0 13.3 17.0 11.3 17.4 22.3 82.9 13.9 12.3 20.0 18.5 17.3 18.9 12.2 21.6 11.2 16.8 29.1 14.1 19.4 11.4 9.4 19.8 57.9 19.3 5.6 12.0 7.0 2.7 7.5 3.8 9.2 15.7 14.9 10.0 2.9 8.1 9.0 9.3 4.8 21.6 18.7 21.7 8.6 11.8 8.3 10.5 11.4 3.7 10.3 4.4 12.5 3.8 6.2 23.0 12.8 18.3 22.9 4.9 4.9 1.9 11.9 16.0 10.5 6.2 25.5 8.5 0.7 10.0 12.1 7.7 0.3 0.7 17.2 7.4 13.6 15.3 11.8 10.6 5.4 4.8 8.4 3.5 4.1 14.9 10.8 11.4 2.7 2.4 8.0 2.7 14.7 10.4 6.3 14.0 16.7 1.8 13.7 13.6 8.1 8.8 19.3 9.0 9.4 5.9 7.2 19.8 7.0 4.9 6.0 57.9 5.6 15.5 6.2 12.0 7.0 23.4 23.1 27.3 22.6 18.8 16.6 20.1 19.2 19.0 21.6 26.8 16.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.3 27.9 0.0 25.8 18.3 11.9 0.0 0.0 0.0 0.0 5.1 13.7 0.0 0.0 7.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 12.6 0.0 0.0 7.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288710-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA Vesicles "HPA035445: AB_10669860, HPA035446: AB_2732468" "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 40.1 16.8 20.8 16.5 23.1 6.8 21.9 16.6 21.4 18.6 27.2 12.0 12.8 21.9 13.7 15.5 20.6 11.4 16.1 20.0 19.4 18.0 44.4 44.3 26.8 17.8 27.3 16.5 11.9 14.2 14.5 16.1 17.0 23.1 19.8 26.3 15.1 22.2 14.5 22.0 13.3 25.8 30.1 27.3 14.1 18.1 8.3 20.9 20.7 42.4 14.2 19.4 24.2 22.6 13.2 29.6 13.4 31.2 6.4 11.6 16.9 15.9 12.8 18.4 16.9 27.3 26.0 15.6 26.2 31.8 22.6 28.8 22.2 12.2 24.3 22.5 24.8 25.6 13.2 0.0 19.6 28.6 14.4 12.3 32.3 17.2 35.2 24.3 43.1 18.2 29.3 23.7 21.0 17.9 20.5 20.4 17.9 40.0 14.7 30.0 15.1 28.5 20.0 15.1 8.0 15.9 13.4 22.6 19.9 41.1 19.8 21.1 20.6 14.7 0.5 35.9 14.6 0.5 50.5 21.1 13.9 22.3 35.0 29.1 19.0 38.0 31.9 25.4 37.8 32.6 6.2 31.2 10.0 11.0 25.6 11.6 12.8 9.5 10.8 29.6 13.2 11.6 11.6 13.4 6.4 17.9 22.6 9.6 16.9 20.8 23.1 16.6 21.4 19.4 18.0 27.3 16.5 23.1 20.9 89.3 91.1 32.9 31.3 23.2 25.4 53.7 25.5 48.2 87.6 29.6 29.5 92.5 107.8 66.8 54.2 29.5 50.2 0.0 69.9 70.0 41.4 25.3 42.7 52.3 76.6 27.0 13.3 22.1 48.0 20.2 30.5 56.1 33.7 19.0 31.2 28.6 47.4 28.1 29.4 160.1 37.1 25.8 25.6 26.9 22.6 19.9 54.8 31.9 50.3 46.0 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362480-133373689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.2" "Cell type enhanced" "Detected in all" 11 "Hepatocytes: 1338.6;Proximal tubular cells: 2021.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1500000 Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 36.5 18.7 16.6 9.1 16.6 5.0 15.2 8.2 18.3 8.8 21.8 13.0 34.7 22.8 9.5 14.1 16.5 12.2 17.4 29.8 14.6 11.5 62.1 148.2 6.3 7.8 14.8 10.3 11.6 16.3 9.2 11.0 12.8 11.1 13.9 14.0 11.0 40.2 38.4 35.7 8.8 32.1 9.9 11.9 7.3 11.0 10.2 10.2 3.9 16.2 17.5 13.0 11.2 7.8 39.4 53.7 18.3 45.7 33.5 32.1 44.5 28.9 36.3 19.8 49.3 28.7 18.6 18.1 21.3 28.2 29.8 25.2 79.7 28.1 21.8 18.5 23.9 15.6 27.2 25.7 21.6 21.6 16.7 45.0 21.8 22.0 56.6 24.2 28.1 15.5 20.7 18.7 19.7 25.2 26.5 26.3 15.9 19.6 19.2 28.9 68.6 14.0 55.0 13.8 45.9 43.6 24.2 24.0 11.6 36.8 37.1 12.8 20.3 22.0 36.6 27.7 11.9 28.5 27.2 21.1 13.4 19.5 27.9 28.0 14.4 8.8 24.8 31.9 15.4 11.1 17.0 41.7 18.3 24.9 45.7 32.1 39.4 28.1 27.1 53.7 32.2 28.9 27.9 4.4 33.5 34.3 23.2 26.0 44.5 16.6 16.6 8.2 18.3 14.6 11.5 14.8 10.3 11.1 10.2 41.7 72.4 78.2 79.8 60.7 58.8 224.4 180.9 62.9 56.9 165.7 5.9 406.8 479.1 144.4 24.0 65.0 374.4 46.7 88.5 126.6 74.8 83.9 89.0 1338.6 193.8 42.9 126.4 78.5 88.6 29.7 71.9 72.7 128.2 149.7 152.5 112.9 99.9 252.6 86.3 2021.6 42.1 84.1 76.9 50.6 40.1 66.7 250.1 49.0 276.7 103.8 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 37.1;liver: 91.2" "Group enriched" "Detected in many" 7 "Hepatocytes: 227.5;Proximal tubular cells: 124.0" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 16.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 4.1 1.2 1.2 1.7 1.4 0.1 1.5 0.5 1.2 1.7 6.4 0.8 0.4 5.2 1.0 2.0 2.9 0.8 3.0 3.2 1.2 0.9 37.1 91.2 1.9 1.0 1.7 0.7 0.8 2.5 2.7 0.9 1.3 2.1 1.7 2.6 8.3 2.7 0.4 0.7 1.1 9.9 1.0 1.4 1.7 2.4 0.9 0.9 1.4 2.1 1.7 1.2 1.8 1.0 1.5 6.0 0.2 2.2 2.7 2.7 1.1 8.3 3.5 1.0 0.0 5.3 4.5 1.1 4.0 1.2 2.6 3.0 15.2 5.3 0.0 15.9 4.0 1.0 4.1 0.0 3.3 5.5 11.1 3.7 5.9 0.9 15.4 3.5 0.7 0.1 6.4 4.3 2.7 2.4 3.6 3.8 0.0 3.8 4.3 5.0 4.3 0.1 3.5 2.1 3.0 4.4 0.0 7.1 0.3 11.0 4.7 3.2 4.6 7.8 4.6 7.3 9.1 16.8 6.9 1.8 1.7 2.6 1.3 0.3 1.2 3.8 0.3 0.6 2.6 2.8 0.2 2.2 0.0 1.6 2.1 1.0 1.5 1.1 2.4 6.0 0.2 1.6 2.7 0.1 2.7 2.0 2.4 1.4 1.1 1.2 1.4 0.5 1.2 1.2 0.9 1.7 0.7 2.1 0.9 14.9 7.5 13.7 1.5 1.3 0.2 17.9 25.5 4.0 4.5 19.2 3.9 7.2 16.6 2.0 0.1 2.8 13.8 0.0 5.9 2.1 1.5 1.8 0.0 227.5 3.7 0.0 7.5 12.3 12.4 0.0 0.6 1.3 3.3 15.4 11.6 1.7 3.3 8.6 0.4 124.0 0.9 0.0 2.0 3.9 4.1 0.4 1.1 3.2 10.6 1.6 ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879250 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "monocytes: 2408.5;Muller glia cells: 2654.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394" Supported Enhanced "Plasma membrane,Cytosol" NA NA 490000000 "Plasma membrane, Cytosol" "CAB018614: AB_2099061, CAB069394: , HPA068284: , HPA068721: AB_2732119" "unprognostic (6.51e-3)" "unprognostic (9.50e-3)" "unprognostic (3.56e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (2.71e-4)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (2.37e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (1.67e-2)" "unprognostic (1.46e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.36e-3)" 68.6 57.7 92.7 94.9 109.6 121.8 73.4 46.6 119.4 47.3 63.8 74.6 21.7 71.3 44.9 24.2 138.2 52.2 55.0 45.2 79.1 70.7 180.4 165.4 64.8 80.3 74.9 62.7 58.2 31.6 52.7 35.5 70.5 88.6 38.6 66.4 62.6 106.1 69.1 45.0 74.6 70.3 84.0 56.4 80.0 44.3 31.7 48.8 98.8 55.4 91.0 119.3 73.5 62.9 38.7 114.1 22.1 105.4 55.5 63.7 159.3 182.3 159.4 76.9 65.8 64.4 71.9 69.7 99.1 109.9 213.7 200.9 102.1 105.9 131.5 132.4 119.3 87.5 90.0 130.6 264.6 218.0 89.7 138.0 111.0 161.9 126.7 96.7 221.2 68.4 74.2 80.3 169.2 257.3 161.8 136.8 67.1 121.6 51.4 138.5 90.3 83.4 118.4 83.9 65.5 160.0 86.4 114.6 214.7 252.9 43.5 104.0 64.2 116.3 169.4 122.3 96.7 84.8 66.3 125.1 148.0 131.1 126.2 168.6 146.8 104.1 199.5 229.8 181.4 124.2 13.9 105.4 20.8 52.3 75.8 59.1 38.7 55.8 53.8 114.1 32.7 45.6 47.8 22.1 55.5 72.4 31.2 63.7 159.3 92.7 109.6 46.6 119.4 79.1 70.7 74.9 62.7 88.6 48.8 259.1 414.8 250.1 443.8 370.0 168.1 63.1 310.8 202.1 440.2 575.7 66.8 1020.4 784.2 1640.5 217.6 199.3 508.9 23.3 1210.7 1855.9 354.5 232.4 289.9 288.6 1045.8 456.1 181.6 141.8 389.1 532.9 158.8 475.7 425.1 2408.5 221.4 2654.1 1226.2 336.6 126.9 717.5 187.6 148.8 217.3 150.6 148.2 305.6 837.7 297.2 410.6 403.0 ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 119.2" "Group enriched" "Detected in many" 4 "Bipolar cells: 242.1;Cone photoreceptor cells: 294.5;Horizontal cells: 405.2;Rod photoreceptor cells: 613.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 8.2;MAIT T-cell: 9.7;memory B-cell: 5.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 9.6;naive B-cell: 3.3;naive CD4 T-cell: 7.1;naive CD8 T-cell: 7.4;neutrophil: 6.2;T-reg: 5.5" "Group enriched" "Detected in many" 7 "B-cells: 5.6;granulocytes: 6.2;T-cells: 10.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 94.8;U-87 MG: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 89000000 "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: AB_2732119" "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" 4.2 20.7 31.2 8.3 48.0 4.0 4.9 115.2 119.2 7.6 7.9 10.9 2.6 4.9 11.7 6.3 5.9 9.4 8.0 10.3 30.2 39.2 3.5 2.0 10.1 10.5 29.6 47.4 3.7 4.1 19.1 15.5 4.8 47.7 8.0 7.4 28.6 3.1 15.3 2.1 5.8 6.0 15.2 15.7 5.8 6.4 3.2 13.3 1.7 14.2 0.3 10.3 7.1 5.0 5.6 1.0 6.2 0.2 0.4 10.8 4.5 12.2 7.7 2.8 0.1 4.2 4.5 0.2 9.5 6.1 14.1 21.7 1.4 1.0 17.2 1.5 4.1 18.6 1.8 29.3 2.6 21.4 34.4 2.7 23.8 7.9 10.3 3.0 1.3 28.6 2.3 0.1 10.4 2.1 94.8 2.9 22.5 1.5 0.2 9.4 1.6 11.1 1.5 14.9 5.3 4.4 12.4 2.3 3.8 6.9 1.6 22.5 15.8 2.5 0.1 16.2 14.3 0.7 0.7 3.7 12.3 13.0 16.6 12.2 12.6 12.6 2.5 70.7 0.0 2.5 1.3 0.0 0.1 8.2 0.0 9.7 5.6 10.8 9.6 0.0 3.3 7.1 7.4 6.2 0.4 0.2 1.0 5.5 4.5 31.2 48.0 115.2 91.3 30.2 39.2 29.6 47.4 47.7 13.3 32.8 30.1 5.4 2.3 5.6 242.1 12.0 0.0 21.4 10.3 12.2 294.5 0.2 0.0 16.0 0.3 7.1 0.0 0.0 1.5 0.3 6.6 1.7 65.8 0.0 1.7 405.2 23.0 6.2 0.0 0.0 5.2 2.5 11.8 5.4 0.0 91.6 10.4 0.2 9.2 0.0 613.6 12.9 21.7 1.8 1.3 1.9 0.2 11.4 0.4 1.6 ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "skeletal muscle: 638.2;tongue: 320.3" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 511.6;monocytes: 134.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HDLM-2: 71.7;HeLa: 30.7;HMC-1: 30.3;RH-30: 49.3;RPMI-8226: 25.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA000793, HPA068284, HPA068721" Enhanced Supported "Plasma membrane,Cytosol" Yes No 100000000 "Plasma membrane, Cytosol" "HPA000793: AB_1078742, HPA068284: , HPA068721: AB_2732119" "unprognostic (7.35e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.33e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.04e-3)" "unprognostic (2.21e-2)" "unprognostic (4.63e-2)" "unprognostic (5.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (4.50e-2)" 7.6 0.3 0.2 0.6 0.2 0.7 0.5 0.6 0.2 0.2 0.4 0.0 0.1 0.8 0.4 8.5 8.6 0.4 0.1 38.3 0.2 0.1 0.5 5.0 0.4 0.5 0.2 0.0 0.4 0.3 0.3 0.5 0.2 0.1 2.1 0.1 1.2 11.8 0.1 638.2 0.3 0.7 0.4 0.2 0.8 0.4 0.5 0.0 0.6 4.8 320.3 10.5 0.3 0.3 13.3 21.0 27.1 24.8 18.5 23.3 36.0 2.9 6.3 2.9 2.7 2.5 0.7 6.9 5.1 0.7 0.3 0.3 3.0 2.0 5.4 7.0 0.4 0.9 3.7 1.0 0.4 0.3 71.7 5.8 5.2 30.7 4.5 0.9 1.6 30.3 4.2 1.0 0.5 1.0 2.6 0.3 6.2 2.4 9.9 1.5 1.6 1.9 6.3 3.7 0.8 2.6 8.5 49.3 25.8 0.7 1.9 1.8 6.9 3.3 2.8 3.7 2.0 2.6 1.7 1.6 3.0 5.7 1.3 3.8 7.0 3.9 4.4 1.7 5.1 3.0 13.5 15.6 27.1 21.8 22.5 14.7 13.3 18.7 20.3 21.0 11.1 12.3 19.7 19.7 18.5 24.8 16.6 23.3 36.0 0.2 0.2 0.6 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.0 2.6 2.9 1.0 1.8 3.2 511.6 0.0 0.0 2.3 5.2 3.9 4.3 0.0 1.4 1.3 2.2 4.3 0.0 0.7 3.1 3.6 1.0 8.1 38.1 4.4 3.2 0.0 3.1 3.8 2.7 0.3 4.5 1.7 134.3 2.3 1.5 1.3 1.7 0.4 5.4 2.4 6.5 0.9 8.6 3.9 1.6 2.7 4.3 2.1 0.6 ENO4 "AC023283.3, C10orf134" ENSG00000188316 "Enolase family member 4" A6NNW6 10 116849512-116911788 "Enzymes, Predicted intracellular proteins" Glycolysis Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.1;epididymis: 12.6;fallopian tube: 13.6" "Cell type enhanced" "Detected in some" 16 "Ciliated cells: 36.1;Cone photoreceptor cells: 21.6;Early spermatids: 11.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 2.7;MCF7: 8.3;T-47d: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037937, HPA037938" Enhanced Approved Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "HPA037937: AB_10697089, HPA037938: AB_2675746" "unprognostic (2.92e-3)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (6.55e-4)" "unprognostic (8.38e-5)" "unprognostic (1.88e-1)" "unprognostic (2.21e-1)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (3.74e-3)" "unprognostic (2.06e-1)" "unprognostic (2.20e-3)" "unprognostic (1.18e-1)" "unprognostic (9.77e-3)" "unprognostic (9.87e-5)" "unprognostic (1.08e-2)" 0.7 2.1 4.3 0.6 4.3 0.2 2.2 2.6 3.6 1.7 1.0 8.0 0.9 0.3 4.3 12.6 1.4 13.6 1.3 0.5 6.4 4.7 2.3 2.7 3.9 1.2 4.1 4.8 4.2 3.2 3.7 3.4 0.5 12.1 2.1 0.8 3.0 1.6 1.2 0.2 1.1 0.5 0.9 4.4 0.5 0.8 8.8 1.9 0.2 4.2 0.0 0.6 1.8 0.5 1.8 1.0 0.0 0.6 0.0 1.2 0.1 1.5 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.3 1.1 0.0 0.9 2.1 0.2 2.7 0.0 0.7 0.8 0.0 1.5 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.6 0.6 0.0 0.9 0.1 1.1 0.1 0.0 0.7 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 1.2 0.6 0.9 0.0 2.2 0.1 0.0 1.8 5.2 0.0 0.5 0.0 0.8 0.4 1.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.4 0.0 1.6 0.2 0.0 0.3 1.8 0.2 0.0 0.0 0.0 0.2 1.0 1.2 0.1 4.3 4.3 2.6 3.6 6.4 4.7 4.1 4.8 12.1 1.9 0.0 0.0 0.0 0.2 0.1 4.4 0.2 0.0 36.1 0.0 0.0 21.6 0.2 0.0 0.3 11.9 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 4.8 1.7 0.0 0.0 8.8 1.1 0.1 0.0 1.0 0.0 1.3 0.2 0.0 0.7 0.6 9.0 0.0 0.2 7.6 2.7 0.0 0.1 0.0 0.1 0.0 ENOSF1 "HSRTSBETA, rTS, TYMSAS" ENSG00000132199 "Enolase superfamily member 1" Q7L5Y1 18 670324-712676 "Enzymes, Predicted intracellular proteins" "Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Proximal tubular cells: 181.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047829 Enhanced NA NA "HPA047829: AB_2680170" "prognostic favorable (2.27e-4)" "unprognostic (8.03e-2)" "unprognostic (2.02e-2)" "unprognostic (7.87e-3)" "unprognostic (1.85e-1)" "unprognostic (4.29e-2)" "unprognostic (6.48e-3)" "unprognostic (1.55e-2)" "unprognostic (3.50e-3)" "unprognostic (1.33e-3)" "unprognostic (2.44e-2)" "unprognostic (5.07e-3)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.36e-1)" "unprognostic (5.03e-2)" "unprognostic (1.31e-2)" 8.5 22.0 5.4 11.7 9.4 11.0 10.7 2.2 7.6 12.3 12.7 26.1 15.9 12.1 11.8 10.9 10.4 10.4 11.6 10.0 6.3 5.6 36.7 26.0 15.0 10.4 10.2 6.0 9.6 13.3 13.1 19.8 8.9 12.3 16.3 11.5 18.4 16.4 19.6 9.9 8.3 13.8 14.6 7.0 10.1 12.3 6.5 9.8 12.7 21.2 7.8 8.3 8.8 7.7 2.3 4.3 2.4 3.4 2.9 7.0 2.5 4.1 13.7 7.2 6.5 3.7 3.1 5.2 5.6 6.9 3.6 5.3 12.4 11.7 6.7 1.9 5.3 5.5 3.2 9.5 8.2 2.6 3.2 4.9 10.9 15.6 7.2 13.3 19.2 2.7 5.8 9.3 3.7 6.3 1.5 7.9 12.9 7.4 6.9 5.5 12.3 11.6 5.9 5.8 19.4 7.5 5.8 1.8 18.5 10.8 17.7 8.2 2.9 13.6 11.6 2.6 2.7 3.9 13.9 6.4 1.9 5.0 8.6 1.7 12.6 11.1 11.0 14.8 7.6 2.6 0.0 1.6 2.4 7.0 3.4 6.9 2.3 4.9 4.1 2.5 0.8 6.9 5.6 0.1 2.9 1.6 4.3 3.4 2.5 5.4 9.4 2.2 7.6 6.3 5.6 10.2 6.0 12.3 9.8 32.8 79.3 9.0 26.1 10.5 35.7 15.7 25.5 93.7 52.4 45.4 110.0 37.7 97.8 27.3 5.8 15.7 35.9 0.0 12.7 21.5 19.5 28.9 21.9 51.4 33.4 0.0 23.7 25.2 8.4 4.9 21.9 20.8 18.6 16.2 32.4 43.5 19.2 42.1 26.5 181.7 106.8 12.9 11.8 11.7 32.1 10.7 31.6 17.0 43.8 18.2 ETNPPL AGXT2L1 ENSG00000164089 "Ethanolamine-phosphate phospho-lyase" Q8TBG4 4 108742040-108763054 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.5;liver: 111.0" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 9.4;Hepatocytes: 22.6;Muller glia cells: 6.4" "Group enriched" "Detected in some" 23 "glioma: 7.9;liver cancer: 21.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 11.0;Hep G2: 4.3;NTERA-2: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044546, HPA072938" Approved Approved Nucleoplasm Yes NA Nucleoplasm "HPA044546: AB_10962867, HPA072938: AB_2686560" "unprognostic (5.20e-3)" "unprognostic (1.33e-1)" "unprognostic (3.93e-1)" "prognostic favorable (9.52e-5)" "unprognostic (5.93e-3)" "unprognostic (3.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.32e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (1.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (9.48e-2)" 1.2 1.9 50.8 1.3 51.3 1.2 1.3 7.9 53.5 1.3 1.2 13.4 0.0 1.3 1.4 1.2 1.3 1.2 1.4 3.2 37.5 20.1 6.2 111.0 1.2 1.2 26.0 28.7 1.3 1.2 1.4 0.1 1.2 15.7 1.2 1.2 0.5 19.9 1.3 1.6 1.2 1.2 1.2 7.3 1.6 10.4 1.5 18.7 0.0 1.9 0.0 1.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.0 0.1 11.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 2.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.9 0.1 0.2 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.8 51.3 7.9 24.9 37.5 20.1 26.0 28.7 15.7 18.7 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.6 1.0 1.3 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Proximal tubular cells: 175.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favorable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" 10.4 17.0 10.4 6.7 9.9 6.5 9.2 8.6 12.7 6.8 21.7 9.3 8.2 26.7 9.8 10.9 14.8 5.8 10.2 15.8 10.9 11.4 46.8 43.6 5.6 5.2 10.1 9.4 7.9 17.4 9.0 11.1 10.4 9.9 8.1 11.1 8.5 9.1 9.8 20.2 12.4 24.8 6.9 8.8 6.3 14.9 6.9 9.5 4.7 12.5 19.0 5.7 9.9 7.9 18.5 23.1 8.6 27.5 19.6 16.0 13.7 8.4 19.1 9.1 16.1 12.1 8.8 5.7 13.9 6.9 9.3 10.2 12.2 8.8 5.4 11.7 8.6 14.4 17.4 7.1 11.2 8.4 8.2 16.9 4.8 16.5 28.1 11.8 8.3 9.4 11.6 14.7 8.5 5.7 7.9 12.1 6.6 5.0 5.7 11.6 38.7 4.5 12.6 5.4 7.8 14.3 10.4 12.4 15.2 33.4 10.6 17.8 14.8 18.2 14.7 21.8 6.4 21.5 5.7 17.6 15.3 10.9 9.0 7.5 8.2 17.2 6.4 9.7 6.1 6.5 6.5 23.5 8.6 14.4 27.5 13.0 18.5 14.5 15.7 23.1 16.9 16.0 14.9 2.0 19.6 19.1 17.9 14.7 13.7 10.4 9.9 8.6 12.7 10.9 11.4 10.1 9.4 9.9 9.5 23.8 16.0 12.3 12.4 12.5 20.0 37.0 22.9 17.4 17.0 40.1 25.5 18.6 43.1 43.5 88.6 14.7 72.1 23.3 34.0 12.3 14.7 9.4 4.7 30.5 26.4 17.5 28.2 8.0 8.1 38.9 13.6 18.2 15.1 23.4 22.1 16.9 34.9 30.9 14.5 175.3 22.4 12.9 14.1 7.0 8.3 21.0 12.8 10.7 41.2 8.1 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078333-82098332 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 147.6" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 103.0;Hepatocytes: 169.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 155.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 1600000 "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 147.6 7.8 8.2 14.2 11.5 11.1 57.5 19.1 23.0 6.6 27.7 17.0 14.1 8.2 4.7 14.2 17.1 4.3 19.4 6.3 7.9 6.7 3.7 30.8 26.8 9.8 7.3 11.5 6.4 10.4 6.7 15.3 8.4 21.7 28.8 3.4 7.6 16.9 10.8 7.5 17.2 6.5 4.6 8.4 5.1 11.9 6.6 8.8 1.9 5.1 10.7 5.4 8.0 6.6 0.5 1.4 0.0 0.8 0.2 1.9 0.8 23.6 24.8 11.5 7.9 18.7 12.7 24.7 4.7 6.1 5.0 9.2 25.9 16.1 7.9 3.9 3.6 14.0 19.7 11.1 21.7 0.9 3.7 48.3 16.3 18.5 34.6 5.3 8.8 2.5 12.1 5.7 12.7 3.0 1.7 5.6 7.4 24.6 7.0 1.7 40.9 9.5 14.0 22.4 3.7 14.4 8.5 6.5 15.6 5.6 30.3 28.7 16.0 6.9 155.8 12.6 4.4 27.8 16.8 9.7 7.3 15.1 6.0 11.3 9.5 2.1 8.1 4.4 9.6 10.8 0.0 0.8 0.0 1.2 0.5 0.7 0.5 1.9 1.4 1.4 0.2 0.7 0.6 0.0 0.2 0.4 1.1 0.6 0.8 8.2 11.5 19.1 23.0 7.9 6.7 7.3 11.5 21.7 8.8 23.8 103.0 0.8 10.3 6.9 24.9 4.8 25.5 6.7 10.3 10.4 5.9 28.9 3.3 18.9 1.2 4.5 20.8 23.3 24.9 65.8 10.4 65.5 12.7 169.2 11.7 28.6 17.4 11.1 6.9 1.3 15.3 5.0 16.9 8.2 18.9 12.3 16.1 17.5 10.6 5.5 9.5 0.0 9.6 1.9 13.9 12.0 24.7 10.7 18.3 17.5 FECH ENSG00000066926 Ferrochelatase P22830 18 57548283-57586772 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 87.9" "Group enriched" "Detected in many" 5 "Distal tubular cells: 132.6;Erythroid cells: 210.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044100, HPA048177" Approved NA NA "HPA044100: AB_2678809, HPA048177: AB_2680300" "unprognostic (2.30e-1)" "unprognostic (3.17e-2)" "unprognostic (4.59e-3)" "unprognostic (6.85e-2)" "unprognostic (7.60e-2)" "unprognostic (1.08e-1)" "unprognostic (3.86e-2)" "unprognostic (3.34e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-1)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "prognostic favorable (2.38e-10)" "unprognostic (1.10e-1)" "unprognostic (8.30e-2)" "unprognostic (4.05e-3)" "unprognostic (3.58e-2)" 10.0 18.0 9.9 6.5 14.1 87.9 9.9 7.9 17.4 7.9 9.5 23.1 8.0 7.6 10.5 7.9 13.6 8.5 6.9 17.6 10.4 9.7 28.2 28.3 7.2 9.8 12.0 13.9 9.1 9.5 11.4 8.8 14.8 15.6 14.5 9.3 12.1 10.1 11.1 36.2 8.6 7.2 12.3 11.7 10.6 8.5 5.8 13.1 18.4 11.6 10.8 7.1 12.1 8.8 4.2 12.4 14.9 10.9 13.8 9.3 9.1 7.4 20.3 7.4 12.0 4.8 10.9 13.2 10.6 10.9 15.4 13.8 5.4 6.8 3.3 10.9 14.5 8.0 9.5 11.0 8.9 12.4 19.4 11.7 24.6 14.1 11.1 12.3 17.1 44.9 11.3 9.5 9.5 4.4 8.3 11.5 20.7 34.9 14.0 8.6 8.8 17.8 3.6 5.6 4.3 8.8 12.8 10.4 20.0 15.3 14.0 7.5 11.3 13.7 14.8 6.2 6.9 14.1 7.2 9.1 5.4 7.1 2.1 7.7 41.1 17.6 7.2 8.7 8.4 9.0 14.0 9.6 14.9 9.3 10.9 6.7 4.2 5.7 8.3 12.4 2.6 4.2 5.9 0.7 13.8 10.2 9.5 5.9 9.1 9.9 14.1 7.9 17.4 10.4 9.7 12.0 13.9 15.6 13.1 6.0 8.8 5.2 4.9 2.3 3.7 19.8 20.4 9.4 5.7 5.2 3.9 32.2 132.6 15.0 0.4 6.0 5.9 210.2 14.3 16.4 10.4 5.2 16.1 22.9 28.7 7.9 2.4 3.1 6.1 0.7 9.2 10.0 1.7 19.8 3.6 15.1 10.4 5.1 6.7 11.3 4.2 0.0 5.1 2.6 3.8 2.8 20.3 8.3 5.6 3.1 FH fumarase ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519761 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.4" "Cell type enhanced" "Detected in all" 4 "Early spermatids: 161.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 2800000 Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 14.3 28.1 15.7 10.4 20.2 9.3 13.3 15.7 24.4 10.5 22.7 9.9 16.7 23.2 13.7 10.7 17.7 10.3 9.5 59.0 22.9 13.9 35.0 93.4 9.9 13.3 15.2 19.4 9.4 13.9 25.2 11.4 14.3 18.4 12.3 24.4 10.2 18.4 20.6 65.1 13.4 21.4 14.7 14.4 11.1 17.5 14.0 11.7 13.8 12.3 45.2 13.4 13.4 11.2 16.0 26.4 4.5 18.8 10.4 13.9 8.9 29.3 24.6 23.3 21.0 22.9 27.1 37.0 36.4 28.5 41.1 25.8 35.1 18.3 18.6 24.1 27.8 18.0 41.8 35.6 27.0 35.8 21.3 11.5 17.5 26.0 30.0 20.6 40.8 15.9 19.6 16.9 23.0 26.0 14.4 25.2 41.2 53.1 24.1 29.9 14.6 35.1 27.3 24.8 42.8 52.8 29.1 25.5 83.6 39.6 24.9 30.0 26.0 30.6 36.3 23.2 16.8 27.7 27.7 24.8 18.5 23.8 32.6 60.5 21.6 23.1 22.6 20.6 46.9 26.5 4.5 12.8 2.7 9.7 18.8 12.6 16.0 11.4 9.0 26.4 14.1 13.9 12.7 0.7 10.4 15.7 13.2 13.2 8.9 15.7 20.2 15.7 24.4 22.9 13.9 15.2 19.4 18.4 11.7 35.7 27.5 27.0 18.6 17.7 23.0 151.3 33.1 30.8 22.7 22.7 13.7 91.1 66.3 49.6 161.2 17.9 46.4 23.3 39.2 43.6 21.6 16.1 18.5 73.1 45.3 33.4 17.2 11.6 12.6 20.1 22.2 26.8 23.6 29.7 35.6 28.0 29.4 35.1 25.1 58.8 32.6 38.8 21.7 82.8 44.5 16.3 138.9 12.9 60.7 16.3 FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 126.8" "Cell type enhanced" "Detected in many" 16 "Hepatocytes: 338.0;Late spermatids: 92.6;Proximal tubular cells: 322.0" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "T-reg: 2.5" "Lineage enriched" "Detected in single" 25 "T-cells: 2.5" "Cell line enriched" "Detected in some" 29 "Hep G2: 45.4" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 580000 Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favorable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" 0.2 0.0 0.6 0.2 1.6 0.0 0.2 0.2 0.7 0.2 0.3 0.2 0.2 0.3 0.2 2.0 0.2 0.0 0.2 0.2 0.5 0.4 25.9 126.8 0.2 0.2 0.4 0.2 0.2 1.0 0.0 0.2 0.2 0.2 0.3 0.0 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.2 0.1 1.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 45.4 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 2.5 0.1 0.6 1.6 0.2 0.7 0.5 0.4 0.4 0.2 0.2 0.2 0.0 0.0 24.9 0.0 0.1 1.0 1.0 68.8 0.0 0.0 8.7 0.0 0.0 39.7 0.0 75.4 0.6 0.0 0.0 0.0 0.0 0.8 0.5 0.0 338.0 0.1 3.2 0.0 22.7 22.3 92.6 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 322.0 0.4 0.0 0.1 10.7 12.2 0.4 0.0 6.9 0.0 0.0 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 53.9" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 9.8;Distal tubular cells: 6.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 10.8;HEL: 34.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "olfactory region: 888.9" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 1.2 2.0 14.5 0.9 28.1 3.7 1.0 10.6 53.9 1.8 1.0 3.1 0.0 1.0 2.6 5.5 1.2 1.1 1.0 1.0 10.8 24.4 6.0 1.0 1.1 1.1 8.6 17.5 1.1 1.1 9.5 2.8 1.4 6.0 1.8 1.0 1.3 1.0 1.3 0.9 1.0 1.1 1.0 2.6 1.0 1.0 4.0 3.4 0.0 1.1 0.0 1.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.4 0.0 3.8 0.0 0.0 0.0 0.2 0.0 1.4 0.9 2.5 3.6 0.0 0.5 0.2 1.7 10.8 1.2 0.3 0.8 1.4 7.4 34.9 3.0 0.1 0.0 0.1 0.6 0.0 3.1 0.0 1.2 0.3 0.0 0.3 9.0 0.1 0.4 0.8 0.0 0.0 4.3 5.2 3.8 0.5 2.6 0.2 4.7 5.0 3.7 1.2 6.6 0.0 1.8 0.3 0.1 0.0 0.0 6.5 0.9 1.3 3.8 0.0 0.0 0.0 6.3 1.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 28.1 10.6 36.7 10.8 24.4 8.6 17.5 6.0 3.4 0.0 0.0 0.0 1.4 0.2 3.8 1.1 0.0 0.0 0.0 0.0 9.8 0.0 6.6 4.2 4.3 0.3 0.0 0.0 4.7 0.1 0.2 0.8 0.0 0.0 3.0 4.8 2.9 0.0 0.3 3.6 0.6 0.2 0.0 0.0 0.0 3.9 4.2 0.0 0.0 0.0 5.4 0.0 0.8 3.2 4.7 0.1 0.5 0.0 0.0 0.3 GAD2 GAD65 ENSG00000136750 "Glutamate decarboxylase 2" Q05329 10 26216307-26304558 "Enzymes, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 66.2" "Cell type enriched" "Detected in some" 11 "Pancreatic endocrine cells: 35.1" "Group enriched" "Detected in some" 21 "glioma: 0.7;pancreatic cancer: 3.0;testis cancer: 1.2" "Region enhanced" "Detected in all" "basal ganglia: 66.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "MOLT-4: 5.2;SCLC-21H: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044637, CAB078177" Enhanced NA NA "CAB078177: AB_2665779, HPA044637: AB_10794053" "unprognostic (8.67e-2)" "unprognostic (1.11e-1)" "unprognostic (4.93e-2)" "unprognostic (2.52e-5)" "unprognostic (5.44e-2)" "unprognostic (8.08e-2)" 1.0 0.9 6.3 0.9 66.2 1.0 0.9 5.6 28.7 0.9 0.9 1.4 0.0 1.2 0.9 1.1 0.9 0.9 0.9 0.9 5.2 13.2 1.0 0.9 0.9 0.9 5.4 10.0 0.9 12.9 0.9 0.4 0.9 6.8 1.2 1.0 0.0 0.9 0.9 0.9 1.3 1.1 0.9 1.3 0.9 1.2 1.7 8.1 0.0 0.9 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 66.2 5.6 18.2 5.2 13.2 5.4 10.0 6.8 8.1 0.0 0.0 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 35.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 21.6" "Cell type enhanced" "Detected in some" 18 "Club cells: 2.3;Collecting duct cells: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 9.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" 0.5 0.3 0.2 0.2 0.3 1.0 0.4 0.5 0.7 0.4 0.2 0.0 0.0 0.1 0.2 1.6 1.4 0.2 2.0 2.3 0.2 0.3 0.7 0.2 1.6 0.3 0.3 0.8 0.5 0.3 0.1 0.6 0.5 2.1 0.5 0.1 0.3 0.3 0.0 21.6 0.8 0.2 2.5 0.7 0.5 0.2 1.1 0.0 0.0 1.2 3.3 0.7 0.5 0.3 1.7 0.5 1.9 0.8 0.5 1.3 0.3 1.3 0.3 0.8 1.1 0.9 0.5 1.6 0.6 0.3 0.3 0.2 1.3 1.2 1.1 0.5 0.2 0.7 0.9 9.9 0.3 0.4 1.7 0.5 1.6 1.6 0.5 0.4 0.9 3.4 0.4 0.6 0.7 0.3 1.0 0.6 1.0 1.2 4.1 0.9 1.1 0.7 1.3 1.9 0.7 0.5 1.9 2.1 1.0 1.0 1.5 1.2 1.0 1.2 0.7 2.9 1.2 1.2 0.8 5.1 1.5 1.4 1.9 0.7 1.6 0.8 0.7 0.6 0.9 1.9 1.9 0.7 0.8 1.0 0.6 0.8 1.2 0.9 0.6 0.4 1.7 1.1 1.0 1.7 0.5 0.8 0.5 1.3 0.3 0.2 0.3 0.5 0.7 0.2 0.3 0.3 0.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 2.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 GGACT A2LD1 ENSG00000134864 "Gamma-glutamylamine cyclotransferase" Q9BVM4 13 100530164-100589528 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 47.0" "Cell type enhanced" "Detected in many" 10 "Proximal tubular cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "SCLC-21H: 55.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065320 Enhanced NA NA 75000 "HPA065320: AB_2685466" "unprognostic (1.93e-1)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (1.30e-3)" "unprognostic (9.12e-3)" "unprognostic (1.64e-2)" "unprognostic (1.58e-2)" "unprognostic (2.07e-2)" "unprognostic (7.41e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-2)" "unprognostic (2.45e-1)" "unprognostic (1.95e-2)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" 3.6 6.6 3.2 3.4 3.4 0.9 3.4 2.6 4.5 2.0 4.9 3.6 1.7 5.7 4.0 3.4 2.8 2.5 5.5 1.7 2.6 2.2 47.0 10.9 2.4 4.6 3.5 2.1 2.5 9.8 1.8 1.9 2.1 4.4 2.4 3.4 4.1 12.0 14.2 2.7 3.1 6.7 3.4 4.3 6.1 4.4 11.0 3.3 3.7 2.5 5.0 6.4 2.5 2.5 5.2 4.2 1.0 7.5 8.0 8.3 4.2 5.6 0.7 4.6 5.0 3.9 6.1 2.0 3.5 0.9 0.6 1.6 0.0 5.1 0.5 2.0 2.5 0.1 0.3 0.7 1.0 0.2 7.9 3.1 2.3 0.5 0.3 5.6 3.3 7.8 7.2 4.0 0.1 0.3 0.0 2.3 2.6 1.2 0.1 0.9 0.3 0.5 0.4 0.2 10.8 1.5 0.3 1.1 0.6 5.7 0.9 55.0 2.1 1.1 2.5 2.5 4.5 2.4 11.2 2.2 0.0 0.0 1.2 0.9 3.0 1.6 0.2 0.3 2.5 2.5 0.0 5.1 1.0 7.9 7.2 7.3 5.2 6.4 8.3 4.2 5.0 4.0 5.9 0.0 8.0 7.5 3.0 6.5 4.2 3.2 3.4 2.6 4.5 2.6 2.2 3.5 2.1 4.4 3.3 0.0 1.0 10.4 3.4 2.4 1.1 0.8 0.0 0.0 2.3 7.0 13.7 9.8 6.6 8.4 4.1 3.1 5.3 0.0 9.0 10.2 2.8 2.2 5.7 13.2 10.5 1.6 7.5 4.3 7.8 6.7 2.6 3.6 0.0 8.2 4.5 4.8 8.0 2.9 3.5 65.3 2.1 6.5 0.9 18.2 10.5 1.8 3.7 5.0 7.1 1.6 GGCT "C7orf24, CRF21, GCTG, Ggc, MGC3077" ENSG00000006625 Gamma-glutamylcyclotransferase O75223 7 30496621-30504844 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA020735, HPA029914" Approved NA NA 2400000 "HPA020735: AB_1845754, HPA029914: AB_10602321" "prognostic unfavorable (7.68e-4)" "unprognostic (2.66e-1)" "unprognostic (2.51e-2)" "unprognostic (2.62e-1)" "unprognostic (2.54e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.33e-3)" "unprognostic (2.19e-2)" "unprognostic (6.42e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-1)" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (8.12e-3)" "unprognostic (2.00e-3)" "unprognostic (9.92e-2)" 30.8 18.6 15.5 14.5 15.9 10.2 26.4 10.8 25.6 12.6 20.2 7.3 19.3 16.7 10.4 59.6 33.4 13.5 22.5 12.2 14.6 12.4 22.0 18.7 14.6 13.6 11.6 14.4 15.2 17.2 14.9 11.4 18.5 15.0 14.3 21.9 8.0 23.9 19.2 12.6 29.8 16.8 14.2 9.9 13.2 13.3 8.1 5.8 11.0 28.7 32.1 18.9 17.4 19.1 14.8 21.7 5.6 12.8 15.3 16.4 10.1 40.4 10.6 17.3 23.3 7.3 13.3 20.2 13.8 5.4 13.3 16.2 14.1 14.2 26.2 9.2 5.2 15.1 51.6 18.2 14.5 17.5 5.0 20.1 18.5 21.5 18.5 9.6 31.0 14.3 12.9 11.7 13.9 18.0 4.6 13.4 12.6 26.2 15.1 10.5 22.4 18.7 42.0 25.1 41.6 17.2 18.9 20.1 26.0 12.8 37.0 22.0 22.2 12.4 77.7 14.8 23.5 49.8 29.5 8.0 8.8 16.5 16.6 27.0 11.1 26.2 20.2 6.8 42.2 16.3 5.6 12.8 4.2 9.6 12.5 13.3 14.8 12.7 12.3 21.7 11.7 12.3 11.9 0.7 15.3 7.3 19.1 16.4 10.1 15.5 15.9 10.8 25.6 14.6 12.4 11.6 14.4 15.0 5.8 14.9 29.6 26.1 44.9 68.5 23.0 43.7 20.4 81.7 51.2 41.8 3.9 343.3 104.5 74.5 21.3 42.7 45.1 0.0 69.7 113.6 40.1 51.8 26.5 45.3 113.3 31.8 27.2 28.8 40.5 6.6 23.0 53.5 59.1 21.6 78.5 20.5 50.0 49.1 36.7 159.0 11.6 25.8 43.2 13.5 16.0 65.4 113.4 30.2 117.6 52.0 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544723-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" Lyase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 74.8" "Cell type enhanced" "Detected in all" 6 "Hepatocytes: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 7.1 7.8 4.8 4.2 6.3 1.6 10.8 6.3 6.6 6.4 4.9 5.4 8.3 4.0 6.3 8.1 6.5 5.9 7.0 6.8 5.4 3.6 9.0 74.8 8.1 5.4 5.4 5.0 7.0 11.4 15.1 5.6 13.8 5.9 6.3 5.5 5.8 7.4 7.9 6.8 4.9 5.5 7.2 5.1 4.5 6.0 3.6 5.7 3.4 8.5 5.3 5.4 7.3 6.0 0.9 4.9 6.0 7.2 2.2 3.2 3.2 6.8 11.2 8.0 8.9 40.4 11.5 17.8 12.3 14.6 9.1 13.0 19.3 8.5 2.5 12.6 20.2 11.4 11.3 5.7 15.5 10.1 4.4 7.8 4.5 7.5 18.2 15.0 2.8 4.2 14.3 9.2 18.5 12.6 15.1 12.9 4.4 5.3 3.6 26.4 9.0 1.4 2.1 3.7 19.4 9.7 2.6 18.8 6.2 12.7 13.3 3.0 5.1 11.0 21.9 11.4 14.2 10.7 2.7 11.8 11.7 10.3 11.4 8.4 2.9 7.9 2.1 11.3 2.9 16.4 6.0 7.2 3.6 3.2 7.2 3.0 0.7 1.3 1.2 4.9 0.9 3.2 3.0 3.2 2.2 4.4 4.0 1.9 3.2 4.8 6.3 6.3 6.6 5.4 3.6 5.4 5.0 5.9 5.7 26.8 38.9 20.9 16.3 16.7 19.1 20.2 35.7 14.7 17.0 27.9 15.7 51.8 6.6 24.1 3.2 18.0 14.4 23.3 34.3 40.8 26.7 15.3 15.1 132.3 27.6 7.9 13.8 24.5 21.6 1.3 18.7 22.6 20.3 28.9 15.2 19.0 23.2 12.4 19.1 21.4 28.4 6.5 16.5 16.9 8.1 13.2 45.0 14.9 15.8 18.8 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703141 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 249.9" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1600000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 22.2 30.5 42.1 19.5 42.3 11.4 32.0 25.4 42.3 27.1 42.1 19.7 22.9 48.1 25.3 49.2 28.2 31.5 17.8 39.2 37.8 37.7 37.1 65.3 30.7 31.6 38.9 29.7 37.6 25.9 33.2 12.6 26.7 40.6 74.0 22.7 21.7 21.7 28.2 57.5 31.3 64.3 28.9 37.6 25.6 21.3 12.9 21.4 19.8 32.6 42.5 24.3 28.6 24.7 25.9 28.6 8.5 15.6 10.8 24.4 14.7 18.5 8.6 24.8 24.6 11.8 21.3 21.9 16.2 15.4 22.8 23.8 20.9 7.1 20.7 12.8 12.9 27.2 12.3 21.2 20.9 28.9 18.8 32.7 30.6 11.1 19.5 17.7 11.6 249.9 18.2 12.9 21.6 15.5 14.9 24.6 14.7 24.1 13.8 21.3 15.7 18.1 14.8 17.8 16.6 16.9 15.8 30.0 13.5 20.8 14.1 19.3 19.5 11.4 15.9 30.5 17.8 18.4 58.4 10.1 17.8 16.4 15.4 25.6 10.9 20.5 56.8 6.4 30.1 28.5 8.5 9.8 6.9 18.0 15.6 24.4 24.7 18.1 18.3 18.3 25.9 17.1 17.9 1.2 10.8 12.1 28.6 15.7 14.7 42.1 42.3 25.4 42.3 37.8 37.7 38.9 29.7 40.6 21.4 122.1 136.6 86.9 79.7 57.5 55.3 121.3 48.4 88.3 91.0 85.5 19.6 91.3 210.5 107.2 3.6 70.9 36.2 0.0 64.3 264.4 68.8 192.8 67.2 86.8 68.4 65.2 35.1 200.1 112.1 4.7 77.6 69.2 99.5 129.8 41.3 160.8 66.2 35.7 103.3 107.3 50.7 45.3 65.9 11.9 15.7 77.0 61.2 59.9 55.5 125.1 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182381704-182392206 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Late spermatids: 6809.8;Muller glia cells: 5699.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 92.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 92.2" "Cell line enhanced" "Detected in many" "ASC diff: 141.5;ASC TERT1: 100.1;HSkMC: 86.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 28000 "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 173.3 19.2 83.7 37.2 91.0 47.6 63.1 48.5 80.7 41.9 20.4 49.9 9.4 6.2 20.5 29.7 54.0 31.6 26.2 23.5 74.0 48.7 15.6 64.9 39.5 36.9 71.0 48.8 66.2 49.0 7.4 8.9 41.8 70.6 17.4 23.3 39.3 30.4 25.5 159.8 27.9 16.4 30.5 51.3 36.1 71.4 24.0 55.2 8.6 63.9 15.5 24.2 34.7 32.2 2.5 11.0 92.2 21.1 3.4 6.3 18.6 3.0 1.2 14.0 0.0 141.5 100.1 10.3 5.1 16.6 3.1 2.8 7.4 3.1 2.6 5.6 9.9 2.8 7.0 6.1 36.4 2.6 7.0 17.0 34.3 5.8 14.3 7.5 15.1 27.4 86.5 43.7 3.9 46.4 4.7 6.2 8.4 28.8 1.5 11.0 1.7 23.5 14.5 10.4 4.2 6.5 8.5 3.7 4.4 5.4 13.3 9.6 6.3 1.4 18.7 2.0 11.7 18.2 19.1 4.6 0.1 0.2 0.0 1.1 0.5 0.3 0.0 2.7 8.6 0.5 43.6 21.1 54.9 6.3 20.5 2.6 1.6 4.5 5.2 11.0 2.5 2.3 3.9 92.2 3.4 17.1 6.1 1.7 18.6 83.7 91.0 48.5 80.7 74.0 48.7 71.0 48.8 70.6 55.2 116.1 193.4 39.3 480.1 119.7 83.9 198.1 163.1 242.2 133.1 78.5 49.1 126.6 63.0 92.2 1437.2 175.0 45.7 210.2 99.7 54.7 230.2 354.1 758.5 179.4 734.4 41.3 312.5 129.5 692.2 6809.8 451.3 662.6 129.9 48.7 226.1 5699.1 116.5 83.4 352.5 40.4 128.3 90.5 209.3 38.8 52.4 112.0 196.8 96.9 130.8 1061.5 GMDS "GMD, SDR3E1" ENSG00000112699 "GDP-mannose 4,6-dehydratase" O60547 6 1623806-2245692 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Enterocytes: 143.7;Mucus-secreting cells: 229.6;Undifferentiated cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031528 Enhanced NA NA 41000 "HPA031528: AB_10601016" "unprognostic (5.94e-2)" "unprognostic (3.92e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.89e-4)" "unprognostic (4.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-3)" "unprognostic (7.15e-2)" "unprognostic (2.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-1)" "prognostic favorable (5.93e-4)" "unprognostic (2.45e-1)" "unprognostic (2.84e-1)" "unprognostic (6.68e-2)" "unprognostic (1.12e-1)" 5.1 4.0 6.6 29.6 8.7 3.2 7.6 6.0 6.8 12.9 34.9 2.7 10.4 42.1 4.1 6.4 29.2 4.9 38.5 4.9 5.6 4.6 9.3 15.1 7.8 11.8 4.1 3.7 4.3 27.1 19.3 8.9 3.0 4.0 8.6 34.2 6.3 40.4 7.6 3.3 4.9 43.7 4.4 3.1 6.0 38.4 9.0 3.4 9.3 5.6 9.0 19.6 6.1 6.7 10.5 13.9 6.8 12.3 12.0 12.4 7.3 13.0 3.0 2.2 15.5 3.6 9.8 5.3 3.6 7.6 6.8 6.4 6.7 7.6 6.2 11.2 3.9 6.7 5.1 6.7 12.8 7.9 8.5 8.1 6.0 3.4 31.4 4.0 9.6 6.7 10.8 4.4 5.3 11.2 6.6 7.9 21.4 3.9 2.9 4.3 7.4 13.2 11.4 3.3 70.9 10.4 6.9 5.0 32.0 16.4 17.2 12.4 2.9 3.3 5.2 8.0 10.5 4.8 6.1 3.4 5.2 3.9 5.2 6.4 6.6 9.3 6.6 3.4 6.7 6.9 6.8 12.3 1.4 7.9 7.6 10.6 10.5 9.5 7.8 13.9 5.5 8.3 11.1 3.8 12.0 6.1 5.8 12.4 7.3 6.6 8.7 6.0 6.8 5.6 4.6 4.1 3.7 4.0 3.4 0.0 5.0 14.9 13.0 3.8 4.4 2.4 15.3 13.4 5.7 36.6 0.0 15.2 101.2 29.5 3.9 19.6 143.7 0.0 61.4 22.6 9.3 41.6 4.6 9.9 12.1 7.9 107.1 16.0 7.3 3.6 11.2 7.1 21.9 16.2 229.6 3.1 49.3 77.7 15.6 27.3 0.6 12.9 10.7 4.2 35.3 5.4 14.0 18.1 123.8 40.1 GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666711-155732349 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 55.2" "Cell type enhanced" "Detected in some" 16 "Alveolar cells type 2: 41.4;Club cells: 12.5;Collecting duct cells: 10.4;Distal tubular cells: 16.6;Ductal cells: 15.1;Proximal tubular cells: 10.2" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 7.6;non-classical monocyte: 9.2;plasmacytoid DC: 11.6" "Group enriched" "Detected in many" 27 "dendritic cells: 11.6;monocytes: 9.2;NK-cells: 7.6" "Cell line enhanced" "Detected in some" "HAP1: 6.1;HEK 293: 5.0;Karpas-707: 8.7;MOLT-4: 15.9;RPTEC TERT1: 10.9;RT4: 12.7;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 6100 Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" 10.9 5.3 12.4 10.2 19.9 0.9 11.1 3.4 11.6 13.7 31.2 7.3 2.8 5.6 14.7 6.0 7.0 6.8 8.3 21.0 9.0 7.2 11.6 5.1 13.2 7.3 4.7 12.5 5.4 8.5 55.2 5.8 16.3 6.3 17.2 6.9 39.7 7.0 9.8 4.5 3.6 10.1 18.8 6.6 8.5 12.9 2.1 8.5 4.5 8.1 7.3 5.9 6.4 10.6 0.1 11.6 0.3 9.2 7.6 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 6.1 0.0 0.0 0.0 5.0 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 3.3 0.0 8.7 0.0 0.0 15.9 0.0 0.0 0.0 0.2 3.5 0.0 2.6 10.9 12.7 2.2 8.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.3 0.0 2.3 0.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 7.6 9.2 11.6 0.0 1.0 12.4 19.9 3.4 11.6 9.0 7.2 4.7 12.5 6.3 8.5 8.9 41.4 0.0 0.0 0.0 0.0 0.0 0.0 4.0 12.5 10.4 0.0 0.4 16.6 15.1 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 3.5 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674012-107018524 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 23.0;placenta: 23.6" "Cell type enhanced" "Detected in many" 16 "Muller glia cells: 27.1;Sertoli cells: 103.5;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 12.5;BJ hTERT+ SV40 Large T+ RasG12V: 14.6;HBF TERT88: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain NA NA "CAB009534: AB_2279509" "unprognostic (7.53e-2)" "unprognostic (6.67e-2)" "unprognostic (7.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (6.53e-3)" "unprognostic (9.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.48e-4)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" 5.5 3.3 4.6 1.3 10.9 0.6 3.9 4.3 10.7 19.2 1.5 1.2 1.1 0.9 23.0 5.0 1.3 8.4 2.6 3.8 4.6 4.0 3.2 2.8 11.8 1.6 3.7 5.3 3.9 6.2 1.8 1.5 23.6 5.5 3.2 1.3 1.4 1.4 10.1 4.1 1.4 1.2 18.0 2.4 7.9 1.0 2.8 5.4 0.0 2.4 3.0 1.0 2.2 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 4.3 0.0 0.2 2.6 2.4 0.3 12.5 1.6 14.6 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.2 0.0 7.8 0.0 1.2 0.0 0.1 0.0 0.2 0.0 1.7 0.7 0.0 1.9 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 3.8 0.0 0.8 0.5 0.9 0.2 4.8 4.0 3.3 0.9 1.3 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 10.9 4.3 9.9 4.6 4.0 3.7 5.3 5.5 5.4 0.0 0.3 0.0 1.4 1.4 23.1 5.9 0.0 0.0 0.0 3.5 11.8 0.1 0.0 3.2 2.2 3.9 0.0 0.0 0.2 0.0 6.1 1.1 0.0 0.0 0.3 17.5 0.0 2.5 0.6 4.9 22.7 0.0 3.3 0.0 0.0 27.1 0.5 0.0 23.7 0.0 4.0 103.5 57.5 0.9 1.5 1.0 0.2 0.0 0.0 1.2 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807591 "Enzymes, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 71.6" "Cell type enhanced" "Detected in some" 14 "Alveolar cells type 1: 6.0;Collecting duct cells: 8.7;Ductal cells: 14.1;Proximal tubular cells: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "intermediate monocyte: 5.6;non-classical monocyte: 17.8" "Lineage enriched" "Detected in many" 12 "monocytes: 17.8" "Cell line enhanced" "Detected in many" "HEL: 25.3;Karpas-707: 13.4;MOLT-4: 16.0;RPTEC TERT1: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol NA NA 5200 Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 8.8 5.4 18.7 9.8 42.0 1.8 5.5 12.2 36.8 8.1 14.9 5.7 0.4 4.2 11.3 4.7 5.9 9.5 9.2 12.2 16.1 25.0 9.2 5.4 9.4 6.6 14.5 23.2 3.7 7.4 71.6 3.8 28.0 20.6 9.8 6.2 5.8 3.2 8.7 3.8 2.2 5.9 16.3 6.7 7.2 8.9 2.1 5.5 2.6 4.6 2.4 5.1 8.0 6.8 0.2 1.4 1.1 17.8 0.9 0.0 4.8 0.0 0.2 3.6 0.0 1.2 6.8 0.0 1.1 2.0 0.1 0.0 0.0 0.0 0.0 1.7 0.6 2.9 0.0 7.4 0.1 0.4 0.0 2.7 25.3 0.0 0.0 0.7 0.0 0.0 3.0 0.2 0.0 0.1 2.5 0.0 5.7 0.0 13.4 1.8 1.1 16.0 0.0 0.2 0.0 1.9 1.8 0.5 0.4 25.7 2.4 0.4 4.5 0.0 0.1 0.0 3.7 0.0 0.0 0.0 4.2 0.9 7.2 5.3 0.1 0.0 0.0 9.2 0.0 0.0 1.1 0.4 0.3 0.0 5.6 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.0 0.4 0.9 17.8 1.2 0.0 4.8 18.7 42.0 12.2 36.8 16.1 25.0 14.5 23.2 20.6 5.5 6.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.5 5.0 14.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 1.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 5.1 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696585 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 85.1" "Cell type enhanced" "Detected in some" 21 "Enterocytes: 37.2;Intestinal endocrine cells: 169.6;Mucus-secreting cells: 61.9;Paneth cells: 99.3;Undifferentiated cells: 41.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory B-cell: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 3.7;BEWO: 2.2;CACO-2: 3.2;CAPAN-2: 4.6;SiHa: 4.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.2 0.1 0.2 3.4 0.2 0.0 0.2 0.2 0.2 0.2 38.8 0.2 0.2 28.0 0.3 0.2 0.4 0.2 0.3 0.4 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.5 0.0 0.2 0.2 0.2 0.2 17.5 0.2 0.5 0.2 0.2 1.0 85.1 0.3 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 4.3 0.7 2.7 1.7 0.0 0.0 0.6 1.1 0.1 0.0 3.7 0.0 0.0 2.2 0.2 0.0 0.0 0.0 3.2 4.6 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.5 0.1 0.6 0.0 0.6 4.2 0.3 0.0 1.1 0.4 0.1 0.0 0.0 0.0 0.9 0.1 1.3 0.8 1.3 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.5 0.0 4.3 0.0 0.0 0.7 2.3 0.0 0.0 2.7 0.0 0.0 0.7 0.0 0.6 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.0 1.5 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.3 99.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 41.2 0.0 GUCY2D "CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1" ENSG00000132518 "Guanylate cyclase 2D, retinal" Q02846 17 8002594-8020339 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Cone-rod dystrophy, Congenital stationary night blindness, Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 10.6;retina: 33.3" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 58.9;Rod photoreceptor cells: 55.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 31 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 53 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 4 "JURKAT: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "unprognostic (3.57e-4)" "unprognostic (5.05e-1)" "unprognostic (1.49e-1)" "unprognostic (9.75e-5)" "unprognostic (5.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.44e-2)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" "unprognostic (4.44e-1)" "unprognostic (7.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.46e-1)" "unprognostic (3.08e-1)" "unprognostic (1.07e-1)" 0.1 0.0 0.1 0.3 0.1 0.5 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 1.3 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.4 0.0 33.3 0.4 0.1 0.1 0.4 0.1 0.1 0.1 0.6 0.1 5.0 0.1 0.2 0.1 0.1 0.9 0.1 0.2 0.0 10.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.0 1.2 0.3 2.4 1.6 0.0 0.0 0.0 0.0 58.9 1.2 1.7 0.1 6.8 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.0 0.8 1.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.0 1.0 0.0 2.5 0.2 0.0 0.4 0.5 55.6 0.0 0.0 0.2 0.0 0.3 1.8 0.0 0.0 0.4 GUCY2F "CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2" ENSG00000101890 "Guanylate cyclase 2F, retinal" P51841 X 109372906-109482072 "Enzymes, Plasma proteins, Predicted membrane proteins" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "retina: 23.1" "Cell type enriched" "Detected in some" 33 "Rod photoreceptor cells: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "THP-1: 4.5;U-266/70: 1.6;U-937: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 0.4" NA NA "unprognostic (1.91e-1)" "unprognostic (4.45e-2)" "unprognostic (2.96e-1)" "unprognostic (2.23e-1)" 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HACD1 "CAP, PTPLA" ENSG00000165996 "3-hydroxyacyl-CoA dehydratase 1" B0YJ81 10 17589032-17617377 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Developmental protein, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 80.1" "Cell type enhanced" "Detected in many" 16 "Cardiomyocytes: 116.4;Collecting duct cells: 29.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 10 "T-reg: 27.6" "Lineage enriched" "Detected in many" 16 "T-cells: 27.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-1)" "unprognostic (2.62e-2)" "unprognostic (4.10e-1)" "unprognostic (5.67e-3)" "unprognostic (4.21e-2)" "unprognostic (3.04e-2)" "unprognostic (2.38e-1)" "unprognostic (1.70e-2)" "unprognostic (2.61e-2)" "unprognostic (3.43e-1)" "unprognostic (2.46e-2)" "unprognostic (2.93e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (6.49e-2)" 6.6 4.7 2.1 3.8 3.9 5.4 12.6 3.4 3.1 5.1 17.6 3.9 7.4 2.3 13.1 6.0 12.6 6.5 4.8 80.1 2.4 3.7 3.6 1.1 7.9 1.1 5.1 1.8 3.9 2.5 0.6 2.4 1.5 3.8 8.8 3.3 9.4 2.1 13.2 22.8 2.5 4.2 21.5 4.8 1.5 9.4 3.0 3.4 2.6 5.9 6.2 1.2 12.6 9.8 0.6 1.6 1.7 0.5 1.6 27.6 0.7 10.8 9.3 2.6 12.8 11.9 2.3 0.2 15.4 9.3 20.2 19.1 6.2 13.2 0.1 2.3 25.0 29.1 2.7 6.6 4.7 11.2 7.1 3.9 25.0 6.7 16.9 15.5 0.1 1.9 5.5 6.6 11.6 4.5 15.6 3.9 13.4 0.2 0.5 26.5 7.8 18.4 2.5 5.6 0.8 2.5 16.6 2.7 0.3 7.9 2.1 2.9 7.5 13.1 0.2 21.6 8.6 9.3 6.2 3.7 11.9 6.9 7.2 7.0 0.4 0.3 0.1 8.7 2.8 1.6 1.7 0.5 0.4 0.6 0.1 0.1 0.2 2.8 0.5 1.6 0.6 0.5 0.4 1.6 1.6 0.1 0.8 27.6 0.7 2.1 3.9 3.4 2.8 2.4 3.7 5.1 1.8 3.8 3.4 26.8 12.9 0.0 16.5 0.0 0.6 116.4 2.5 1.4 4.5 29.6 0.0 0.5 3.3 13.0 8.3 4.8 0.0 0.0 6.9 1.6 2.3 12.0 5.8 0.8 5.0 0.0 3.5 11.6 3.5 1.6 1.7 2.4 0.0 1.0 2.3 0.2 18.1 0.0 0.7 2.0 0.5 0.0 25.7 5.5 5.1 0.0 2.5 0.0 3.8 5.5 HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585185 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SiHa: 65.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved NA NA "CAB019282: " "unprognostic (3.04e-2)" "unprognostic (2.51e-1)" "unprognostic (6.11e-2)" "unprognostic (2.65e-3)" "unprognostic (5.36e-2)" "unprognostic (6.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.59e-5)" "unprognostic (6.90e-2)" "unprognostic (7.03e-3)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (1.94e-2)" "unprognostic (2.59e-2)" 43.2 9.7 18.0 11.2 30.0 5.7 16.6 20.5 18.7 14.1 20.4 28.6 7.4 21.2 12.4 13.5 18.8 9.9 12.2 9.9 20.7 13.4 20.7 34.3 13.8 14.1 29.4 12.0 13.8 13.4 15.6 12.5 11.1 18.5 22.1 20.4 7.3 15.5 10.2 5.6 23.2 30.8 12.3 24.9 9.6 15.3 13.3 25.7 9.1 16.0 10.5 19.7 10.9 16.6 4.9 6.4 2.4 3.5 2.9 5.3 2.4 19.6 11.2 7.7 5.6 24.2 5.4 28.7 14.1 5.9 14.7 10.7 22.8 17.5 11.4 10.2 13.5 17.1 43.2 13.8 17.7 15.6 7.2 4.6 7.9 10.5 17.7 7.9 10.5 7.9 7.5 45.7 7.1 20.0 23.1 7.6 7.9 1.6 11.4 8.8 15.3 4.9 3.1 9.9 24.0 9.9 7.6 8.5 12.1 17.8 12.7 13.6 4.2 65.7 14.1 9.0 11.7 14.6 5.4 5.9 15.4 11.6 15.4 13.7 6.8 8.6 9.4 6.9 7.4 8.2 1.5 3.5 2.4 3.6 2.8 5.3 3.4 4.8 4.6 6.4 4.9 4.4 4.3 1.1 2.9 2.2 3.7 5.3 2.4 18.0 30.0 20.5 18.7 20.7 13.4 29.4 12.0 18.5 25.7 6.0 35.5 13.7 26.4 0.0 8.3 12.6 15.3 5.3 28.4 43.6 5.9 20.9 6.6 13.4 12.7 13.7 18.6 0.0 16.5 13.3 10.4 36.8 3.5 42.9 20.1 1.6 15.2 14.7 20.2 7.3 10.6 17.1 0.0 16.2 21.7 13.5 16.4 21.0 16.6 13.9 12.9 6.5 8.8 8.1 20.5 0.0 5.6 11.7 24.7 26.3 HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578352 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA 27000 "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: AB_2684260" "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favorable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" 9.6 37.4 31.0 7.4 36.0 6.2 33.3 28.6 37.6 18.5 12.5 24.2 10.1 12.2 13.1 19.4 8.4 14.3 14.7 5.9 29.2 44.8 35.0 50.0 12.7 7.2 36.5 26.0 21.7 12.6 22.5 33.9 15.9 45.9 18.5 15.1 17.9 11.6 15.8 3.3 11.7 12.0 12.2 41.5 8.5 29.0 13.9 19.7 8.9 30.7 5.6 8.3 18.8 10.4 13.0 9.0 2.7 6.1 11.7 19.9 11.2 19.4 43.6 48.5 24.2 30.6 18.5 23.0 21.6 18.7 24.6 27.8 33.4 29.2 24.5 18.9 23.4 30.7 53.9 78.2 18.0 22.1 13.6 43.6 19.5 21.9 36.4 15.5 24.1 15.0 18.9 13.5 16.8 12.2 23.8 23.9 14.7 25.5 9.3 39.6 23.2 17.8 18.8 41.3 52.2 14.8 20.2 41.1 27.6 35.1 33.9 29.3 25.9 23.3 26.3 24.4 47.7 26.7 12.8 18.9 31.3 27.6 15.3 29.9 18.2 54.0 34.6 20.9 23.6 18.7 2.7 3.9 1.2 17.6 5.8 19.9 13.0 16.1 16.6 6.8 13.0 18.9 18.5 0.4 11.7 6.1 9.0 12.4 11.2 31.0 36.0 28.6 34.1 29.2 44.8 36.5 26.0 45.9 19.7 59.6 49.7 22.9 50.2 0.0 116.3 6.4 61.1 66.9 51.2 167.5 94.2 155.3 21.6 61.1 83.6 35.9 7.7 46.7 39.9 101.8 47.3 63.7 15.1 153.2 44.7 131.9 42.1 42.4 18.0 21.8 80.8 16.2 0.0 3.6 25.8 78.8 35.8 14.0 83.1 44.0 65.7 77.6 27.2 123.2 116.2 0.0 94.6 13.1 52.6 77.6 HACD4 "Em:AL662879.1, PTPLAD2" ENSG00000188921 "3-hydroxyacyl-CoA dehydratase 4" Q5VWC8 9 20999515-21031636 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 44.7;Ciliated cells: 89.7;Hofbauer cells: 50.9;Kupffer cells: 90.6;Macrophages: 52.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 15.8;HDLM-2: 9.6;TIME: 7.9;U-937: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058666 Uncertain NA NA "HPA058666: AB_2683793" "unprognostic (1.71e-1)" "unprognostic (2.58e-2)" "unprognostic (5.47e-2)" "unprognostic (1.70e-2)" "unprognostic (7.66e-2)" "unprognostic (1.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.28e-2)" "unprognostic (1.11e-4)" "prognostic favorable (3.14e-4)" "unprognostic (8.72e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.89e-3)" "unprognostic (7.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-3)" 4.3 7.9 4.9 9.2 7.1 16.3 10.3 3.3 3.1 8.9 10.1 2.6 1.2 3.2 6.9 5.6 10.7 6.5 7.6 7.5 4.1 3.2 3.3 1.8 24.1 18.2 5.2 1.8 6.5 1.9 4.0 2.3 9.9 3.7 5.9 5.0 6.3 3.6 3.8 1.5 4.7 7.5 11.5 9.6 10.1 5.4 1.8 5.5 19.9 4.1 6.2 7.9 5.1 5.6 1.2 8.4 13.6 8.8 3.0 3.0 3.9 3.7 1.1 0.4 0.1 0.0 0.1 0.1 3.4 15.8 2.8 3.2 0.0 0.0 3.4 1.9 6.7 0.0 1.0 0.2 1.4 3.5 9.6 0.1 0.0 1.2 0.0 2.2 2.8 3.0 6.4 6.2 2.5 0.0 0.0 0.9 3.9 0.0 2.0 0.5 0.1 0.0 3.9 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.0 0.8 0.3 0.0 2.3 2.8 5.3 7.9 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 12.1 0.1 13.6 7.1 11.4 2.2 8.8 2.0 1.2 2.4 2.5 8.4 1.2 1.7 2.4 10.2 3.0 8.5 0.9 3.0 3.9 4.9 7.1 3.3 3.1 4.1 3.2 5.2 1.8 3.7 5.5 44.7 6.7 16.7 9.5 0.0 1.4 1.6 0.0 89.7 20.5 12.2 0.0 10.0 5.0 0.5 0.4 3.3 0.0 0.0 0.4 30.5 7.8 3.2 3.5 1.3 50.9 0.0 0.0 9.8 90.6 0.0 3.4 52.2 0.0 14.4 0.0 6.7 0.1 0.0 1.1 5.1 1.5 12.9 7.3 0.3 1.3 0.0 4.2 28.8 0.1 3.8 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244726 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 2700000 Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 41.6 35.3 18.1 13.1 19.5 17.0 23.9 17.4 16.9 20.2 44.9 26.5 15.7 48.1 21.1 15.3 30.8 20.5 15.1 80.0 15.6 15.5 41.3 71.7 17.7 19.3 21.6 13.1 27.3 37.5 29.8 23.5 21.3 24.8 21.9 32.2 23.6 21.1 16.6 117.5 23.3 66.4 25.1 27.8 24.0 24.1 18.7 19.0 25.2 25.1 41.3 24.6 26.9 18.8 15.3 28.9 12.4 32.2 13.5 17.6 26.0 23.6 21.1 13.9 22.7 55.2 34.5 11.8 18.5 20.0 19.1 16.6 26.6 23.0 15.6 12.2 32.6 19.7 15.1 24.3 35.9 17.3 35.0 29.8 23.4 22.4 44.3 19.0 29.4 17.2 35.3 23.6 27.1 27.3 20.0 32.0 16.8 31.8 31.7 24.6 29.0 12.8 33.0 11.9 17.8 40.7 11.9 30.0 33.5 21.9 28.5 9.8 19.5 21.8 22.7 25.1 11.3 12.1 28.6 29.3 11.1 16.5 16.7 13.6 10.4 20.6 27.8 17.4 34.9 13.4 8.1 27.7 12.4 12.3 32.2 14.8 15.3 14.2 15.0 28.9 11.2 16.7 15.3 7.4 13.5 28.0 11.0 17.6 26.0 18.1 19.5 17.4 16.9 15.6 15.5 21.6 13.1 24.8 19.0 83.4 81.9 90.4 122.8 79.0 34.1 285.8 71.4 101.7 126.3 73.3 49.1 149.8 111.0 102.7 26.5 92.1 406.5 23.3 94.5 78.0 88.0 61.7 134.2 168.3 142.3 19.1 87.7 68.7 130.6 58.2 85.7 124.9 77.6 129.0 139.2 61.8 86.9 196.4 79.2 150.1 61.9 51.8 104.9 121.4 35.2 90.3 108.0 105.4 168.5 92.1 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 29.5;liver: 96.8;skin 1: 26.9" "Group enriched" "Detected in some" 13 "Erythroid cells: 46.7;Hepatocytes: 134.4" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 20.1;neutrophil: 29.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 29.5" "Cell line enhanced" "Detected in some" "BEWO: 3.2;NB-4: 4.0;THP-1: 15.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 67000 Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 0.5 0.0 0.1 1.1 0.3 4.4 0.9 0.1 0.3 0.3 0.2 0.1 0.1 0.1 1.1 0.3 0.5 0.2 0.3 0.2 0.1 0.0 0.2 96.8 1.7 2.3 0.5 0.1 0.3 0.5 0.0 7.4 0.4 0.2 0.2 0.0 0.1 0.2 0.1 0.2 26.9 0.2 0.2 0.3 2.7 0.1 0.2 0.2 0.1 0.2 0.9 1.3 0.2 0.5 0.0 1.4 29.5 6.3 0.3 0.1 1.6 0.6 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.2 0.1 0.2 0.0 0.1 0.9 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.2 0.5 0.4 0.2 0.0 0.0 0.6 0.7 0.0 0.9 0.4 0.4 0.1 0.3 0.4 0.0 0.2 0.1 0.0 0.2 4.0 1.3 0.1 0.7 0.3 0.1 0.1 0.1 0.8 0.2 0.4 0.5 0.1 0.0 0.1 0.0 15.5 0.2 0.1 0.2 0.2 0.2 0.7 0.7 0.2 0.0 2.4 0.0 20.1 6.3 0.9 0.0 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 29.5 0.3 5.1 0.1 0.1 1.6 0.1 0.3 0.1 0.3 0.1 0.0 0.5 0.1 0.2 0.2 0.0 1.4 0.0 0.1 0.1 0.0 0.5 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 46.7 0.2 0.2 0.0 0.1 0.0 134.4 0.3 0.0 0.0 1.8 6.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.1 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123078 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 10.6 14.2 8.8 9.0 12.7 11.8 9.6 11.0 17.7 6.7 15.5 7.4 8.0 17.2 8.5 5.5 15.8 6.9 9.8 36.9 8.4 8.3 15.9 19.0 9.5 10.1 8.2 11.1 10.0 11.4 11.5 10.0 12.8 10.6 7.8 15.2 9.3 12.8 8.0 41.6 13.8 14.4 10.4 6.3 12.3 12.2 10.5 6.0 10.3 10.8 16.4 11.8 11.4 17.3 18.1 28.4 13.3 29.7 8.4 11.1 8.7 23.2 26.7 12.5 12.0 11.8 11.4 13.3 23.4 17.9 29.6 25.4 31.0 17.0 14.4 12.1 18.8 33.0 21.6 25.9 22.4 29.0 13.5 20.3 14.5 34.3 15.4 20.9 15.7 17.7 11.1 17.5 28.2 19.3 16.0 21.0 11.1 26.8 16.8 19.9 31.5 11.4 12.8 22.7 14.1 29.0 11.2 25.1 28.4 19.9 18.3 9.0 10.7 23.4 25.5 15.0 27.6 19.7 11.4 20.6 19.2 10.4 49.2 19.9 12.3 12.6 19.2 15.5 12.7 18.4 10.1 22.5 13.3 9.9 29.7 9.5 18.1 9.7 8.9 28.4 15.5 8.5 11.1 6.2 8.4 24.8 25.9 10.4 8.7 8.8 12.7 11.0 17.7 8.4 8.3 8.2 11.1 10.6 6.0 6.0 4.5 22.9 41.8 48.7 5.1 47.6 20.4 16.0 15.9 15.7 0.0 29.4 43.1 32.7 3.8 15.8 37.0 23.3 25.6 30.7 17.7 30.5 12.7 15.3 36.7 7.9 10.4 12.3 22.9 1.3 12.4 23.8 23.6 31.5 20.2 8.7 46.3 31.6 9.9 30.7 7.1 6.5 25.0 13.4 25.4 40.3 34.2 13.8 28.1 88.7 HDC ENSG00000140287 "Histidine decarboxylase" P19113 15 50241947-50266026 "Enzymes, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "blood: 83.5;brain: 36.0;epididymis: 36.9" "Cell type enriched" "Detected in some" 7 "granulocytes: 556.0" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 52 "hypothalamus: 36.0" "Cell type enriched" "Detected in single" 835 "basophil: 83.5" "Lineage enriched" "Detected in single" 835 "granulocytes: 83.5" "Group enriched" "Detected in some" 4 "HEL: 61.2;HMC-1: 147.3" "Region enriched" "Detected in many" 5 "hypothalamus: 51.5" "Low region specificity" "Detected in all" HPA038891 Enhanced Approved "Nuclear bodies" NA NA "Nuclear bodies" "HPA038891: AB_10673231" "unprognostic (4.97e-2)" "unprognostic (7.42e-2)" "unprognostic (1.43e-4)" "unprognostic (1.08e-1)" "unprognostic (6.16e-2)" "unprognostic (3.93e-7)" "unprognostic (4.18e-5)" "unprognostic (8.79e-3)" "unprognostic (1.48e-1)" "unprognostic (8.46e-2)" "unprognostic (4.60e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (7.20e-2)" "unprognostic (9.78e-2)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" 1.7 0.2 0.2 5.1 0.4 2.4 1.1 0.2 0.3 2.7 1.9 0.2 1.2 2.1 3.1 36.9 2.7 0.6 6.6 2.1 0.2 36.0 0.6 0.8 4.9 2.3 0.6 0.1 0.4 0.5 0.3 0.7 0.2 0.3 2.2 1.9 3.0 0.9 1.3 1.8 1.8 2.4 5.4 0.2 0.4 6.9 2.4 0.2 0.4 0.3 0.4 1.7 1.8 2.7 0.0 0.0 83.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 61.2 0.0 0.0 0.0 0.1 147.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.3 0.2 36.0 0.6 0.1 0.3 0.2 11.9 81.4 0.0 0.0 0.7 0.5 0.3 0.0 8.1 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 556.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 HMGCL HL ENSG00000117305 "3-hydroxymethyl-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 81.4" "Cell type enhanced" "Detected in many" 5 "Hepatocytes: 147.7;Proximal tubular cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 120000 "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" 7.4 18.5 6.4 8.2 6.6 1.6 14.3 4.3 7.7 7.6 13.9 9.0 12.0 12.0 6.2 13.2 9.1 9.7 12.8 11.2 5.9 6.0 30.3 81.4 8.8 11.1 7.5 7.1 6.1 15.2 13.1 7.8 8.5 7.9 8.7 14.2 10.0 8.9 11.5 15.2 7.0 15.4 11.7 9.3 8.6 10.8 7.2 6.1 8.3 14.5 8.1 8.3 8.8 6.7 24.1 27.7 40.8 33.8 24.5 21.2 26.8 10.5 6.1 6.9 5.1 28.0 21.4 2.6 8.4 14.7 9.1 11.1 3.8 20.5 5.5 17.3 13.0 7.4 8.5 8.2 13.6 9.9 11.2 6.2 7.4 5.4 8.7 36.2 2.8 4.9 24.8 20.2 11.9 23.0 24.5 12.3 10.5 7.5 7.8 16.6 10.8 4.5 5.7 1.7 28.9 8.5 6.4 5.6 10.2 21.4 5.5 5.8 5.1 10.9 4.1 18.5 9.5 13.0 7.2 9.2 7.5 4.6 13.7 3.6 11.2 5.5 4.9 18.7 10.7 8.8 40.8 32.4 30.1 18.4 30.4 20.1 21.9 20.0 21.2 27.7 24.1 20.3 19.4 12.2 24.5 33.8 20.6 20.8 26.8 6.4 6.6 4.3 7.7 5.9 6.0 7.5 7.1 7.9 6.1 11.9 21.7 21.7 27.4 5.3 24.1 30.3 43.3 28.1 12.5 47.1 17.7 37.1 101.2 42.9 1.5 21.1 59.4 0.0 21.2 21.2 16.6 28.0 17.3 147.7 52.8 33.4 8.6 31.3 25.4 3.2 20.1 21.3 20.3 60.5 44.3 33.5 28.9 49.2 23.0 159.0 20.1 6.5 18.9 4.1 3.3 5.6 34.6 15.2 47.0 22.5 HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434369-55579214 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;pituitary gland: 14.8" "Cell type enriched" "Detected in some" 4 "Bipolar cells: 14.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" 2.2 7.7 7.7 0.9 14.5 0.5 3.4 10.1 18.4 2.2 1.7 3.1 0.3 0.8 0.8 0.6 2.5 1.5 1.8 4.1 8.7 12.6 2.2 1.8 5.7 1.1 9.1 10.0 1.3 3.6 0.8 14.8 12.5 14.6 7.0 2.2 4.8 2.1 2.9 2.4 0.6 2.4 1.6 10.1 0.6 2.9 5.5 3.3 0.0 0.9 0.0 1.0 2.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.3 0.0 0.0 0.0 2.3 0.9 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 14.5 10.1 12.6 8.7 12.6 9.1 10.0 14.6 3.3 0.0 2.2 0.0 0.0 0.0 14.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 0.0 1.4 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 HOGA1 "C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2" ENSG00000241935 "4-hydroxy-2-oxoglutarate aldolase 1" Q86XE5 10 97584323-97612802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 39.8;liver: 31.0" "Cell type enhanced" "Detected in some" 16 "Cholangiocytes: 35.7;Distal tubular cells: 24.9;Hepatocytes: 41.0;Proximal tubular cells: 71.6" "Group enriched" "Detected in many" 5 "liver cancer: 4.5;renal cancer: 9.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "AN3-CA: 6.1;EFO-21: 7.3;Hep G2: 19.0;RPTEC TERT1: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039466 Approved NA NA 15000 "HPA039466: AB_2676522" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (7.50e-2)" "unprognostic (2.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.29e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-3)" "unprognostic (4.72e-1)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (6.80e-2)" "prognostic favorable (9.08e-4)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.94e-3)" "unprognostic (7.20e-4)" 3.3 5.4 3.3 0.6 3.8 0.8 2.1 7.0 4.3 0.8 0.6 8.2 1.5 0.7 0.9 4.0 1.3 2.0 3.8 10.1 4.2 2.8 39.8 31.0 0.9 0.7 9.3 5.2 0.6 12.0 2.0 2.4 0.6 7.2 1.3 0.6 3.6 1.8 2.2 2.0 1.2 0.6 0.8 8.2 0.7 0.6 0.7 6.9 0.0 1.8 4.1 0.6 0.8 0.6 2.1 1.7 4.4 1.2 1.2 1.3 0.5 0.3 2.8 0.1 6.1 1.2 0.3 0.1 0.1 0.2 0.1 0.0 2.3 0.3 0.2 7.3 0.1 0.3 2.0 0.1 0.2 0.1 0.2 3.2 0.1 1.1 19.0 0.8 0.2 0.2 0.3 0.6 0.2 0.1 1.5 0.3 0.1 0.1 0.4 0.5 1.2 0.1 0.2 0.2 0.2 0.0 0.2 0.5 0.4 23.3 0.4 0.5 0.9 0.1 1.1 0.7 0.2 2.1 0.1 0.3 0.7 0.2 0.4 0.2 0.4 0.7 0.1 1.5 0.3 0.1 2.4 1.1 1.2 1.2 0.9 1.0 1.1 1.3 0.9 0.5 2.1 1.1 1.2 4.4 1.2 1.2 1.7 0.9 0.5 3.3 3.8 7.0 3.9 4.2 2.8 9.3 5.2 7.2 6.9 0.0 0.0 0.0 0.6 0.1 0.1 5.3 35.7 5.3 0.0 8.7 0.0 0.0 24.9 4.4 2.9 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 41.0 0.1 1.6 0.0 0.0 1.8 12.3 0.0 0.0 1.7 0.0 0.0 2.0 0.5 0.0 0.0 71.6 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452443-119637199 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hepatocytes: 203.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 6900000 Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 25.1 42.4 22.1 15.5 21.3 6.4 46.0 12.3 23.6 27.8 30.1 24.1 83.8 28.6 16.2 20.7 24.6 15.1 20.6 27.3 23.8 21.2 31.3 116.3 30.5 16.7 27.0 21.7 15.1 29.9 33.2 20.5 19.0 23.9 20.9 25.2 10.7 20.0 86.2 20.7 19.2 30.5 15.6 33.6 16.9 20.7 8.1 25.5 10.8 48.9 17.3 14.5 24.1 25.3 6.1 11.1 31.4 13.6 3.2 4.2 5.3 17.8 15.4 29.0 38.4 72.4 34.0 15.3 17.4 23.5 16.5 30.1 12.7 29.8 23.9 35.9 18.8 24.3 18.0 21.3 37.9 25.8 26.1 19.7 31.4 16.8 24.2 18.4 9.9 49.2 29.6 15.9 17.7 16.7 19.4 28.2 16.5 10.7 13.9 17.9 15.5 15.1 6.4 21.5 44.1 10.9 19.3 29.1 25.8 26.4 49.4 21.9 18.9 40.9 6.4 19.0 28.7 23.7 16.7 20.0 16.2 11.1 17.8 14.2 7.1 14.8 8.8 18.4 26.5 15.9 31.4 13.6 24.7 3.4 8.0 4.2 6.1 3.2 2.9 11.1 5.8 3.1 2.9 2.4 3.2 7.8 6.9 2.0 5.3 22.1 21.3 12.3 23.6 23.8 21.2 27.0 21.7 23.9 25.5 68.5 94.4 20.8 34.3 13.3 18.5 62.9 81.5 24.1 47.8 34.9 13.7 57.8 71.3 28.8 7.4 26.4 50.3 0.0 31.4 21.8 24.2 32.2 65.9 203.2 70.1 14.3 31.7 31.3 50.9 9.3 31.9 35.3 8.5 103.6 42.6 44.1 23.2 24.6 48.1 50.5 15.4 6.5 20.0 15.9 22.2 15.1 54.3 13.1 51.1 31.4 KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 11 "Ciliated cells: 5.3;Cytotrophoblasts: 3.4;Distal tubular cells: 3.3;Proximal tubular cells: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol NA NA 21000 Cytosol "HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818" "unprognostic (6.51e-2)" "unprognostic (8.67e-3)" "unprognostic (1.05e-2)" "unprognostic (5.98e-3)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-2)" "unprognostic (2.47e-1)" "unprognostic (8.60e-3)" "unprognostic (1.43e-1)" "unprognostic (3.65e-2)" "unprognostic (3.10e-2)" "unprognostic (5.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" 4.4 5.2 12.2 5.1 18.9 3.9 7.0 17.8 17.6 4.7 3.8 14.2 5.5 4.1 5.5 5.4 4.6 8.5 4.8 13.5 12.1 9.3 8.1 12.0 4.1 7.3 18.4 12.1 7.1 5.0 8.9 8.1 4.5 12.2 8.9 2.7 5.8 7.0 8.4 17.0 12.2 4.8 5.8 10.2 5.8 4.0 6.9 17.2 3.7 7.5 2.8 7.4 8.1 8.1 12.1 7.6 3.5 5.1 4.6 9.6 4.9 3.8 8.7 8.0 7.9 7.2 9.1 4.1 5.2 6.1 5.2 7.8 4.8 7.1 7.3 2.6 3.9 6.5 12.4 11.8 10.2 6.7 8.2 8.2 4.8 21.2 8.7 6.5 4.6 2.0 4.0 6.5 6.8 6.5 17.5 9.1 18.5 7.3 6.4 6.8 2.5 10.6 3.1 14.0 15.0 6.8 12.7 6.9 13.7 7.1 1.6 8.5 7.3 8.4 2.1 4.8 10.3 5.1 1.7 6.0 3.9 6.8 5.9 4.6 11.9 10.1 9.1 7.5 7.2 3.1 0.1 3.1 3.3 7.8 2.2 6.2 12.1 8.1 8.1 7.6 5.8 8.6 9.6 3.5 4.6 5.1 4.8 8.7 4.9 12.2 18.9 17.8 17.6 12.1 9.3 18.4 12.1 12.2 17.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 1.2 0.0 0.0 3.4 3.3 1.5 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cytotrophoblasts: 59.0;monocytes: 55.9;Syncytiotrophoblasts: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved "Nucleoli,Cytokinetic bridge,Cytosol" NA NA Cytosol "Nucleoli, Cytokinetic bridge" "HPA026538: AB_1852076, HPA027168: AB_1852078" "prognostic favorable (3.19e-5)" "unprognostic (3.36e-3)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.86e-4)" "unprognostic (2.61e-1)" "unprognostic (3.61e-3)" "unprognostic (2.11e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" "prognostic favorable (5.02e-6)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.78e-1)" 22.2 26.8 16.6 13.2 19.3 10.6 27.5 14.9 23.5 23.7 17.5 20.0 13.0 19.4 24.1 21.2 27.2 18.9 17.8 13.2 18.6 14.2 27.3 23.8 17.1 17.6 16.9 22.2 27.4 28.6 27.0 19.5 21.9 23.4 19.0 19.6 19.5 21.0 20.7 10.4 22.0 17.2 22.1 14.8 20.7 23.5 15.6 17.2 15.5 24.5 13.4 20.2 25.2 17.7 9.6 17.0 9.2 12.7 11.5 16.7 8.2 20.8 4.4 21.4 7.1 7.7 21.5 18.6 12.8 24.2 16.5 21.5 6.4 7.3 13.8 9.8 9.5 11.0 5.9 6.0 9.9 25.2 8.1 8.6 12.3 4.2 10.5 25.1 17.2 3.4 18.1 10.0 11.3 20.4 10.5 15.9 16.2 15.9 7.3 15.5 6.9 18.4 8.4 12.7 16.1 3.8 18.8 15.0 7.3 34.6 21.3 15.6 19.1 17.0 22.8 11.1 14.3 12.6 4.2 10.6 6.9 4.6 22.1 9.3 9.9 4.9 9.2 3.4 7.7 5.9 5.6 12.7 7.1 9.1 7.9 12.6 9.6 11.8 10.5 17.0 9.3 12.4 10.4 9.2 11.5 10.2 6.3 16.7 8.2 16.6 19.3 14.9 23.5 18.6 14.2 16.9 22.2 23.4 17.2 11.9 8.3 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.8 12.2 0.0 59.0 21.6 29.8 0.0 0.0 0.0 0.0 33.6 33.1 0.0 0.0 4.7 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 55.9 0.0 0.0 21.3 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 L3HYPDH "C14orf149, FLJ25436" ENSG00000126790 "Trans-L-3-hydroxyproline dehydratase" Q96EM0 14 59460363-59484430 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Ciliated cells: 26.8;Proximal tubular cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056694 Approved Uncertain Vesicles NA NA 16000 Vesicles "HPA056694: AB_2683210" "unprognostic (3.39e-2)" "unprognostic (5.55e-3)" "unprognostic (3.81e-2)" "unprognostic (5.86e-2)" "unprognostic (1.10e-1)" "unprognostic (5.06e-2)" "unprognostic (8.34e-2)" "unprognostic (1.16e-1)" "unprognostic (7.24e-2)" "unprognostic (9.50e-2)" "unprognostic (1.26e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" 17.9 15.4 13.5 13.5 17.1 4.9 22.8 10.4 16.5 12.6 9.9 18.5 10.9 12.3 17.6 10.3 9.8 16.3 13.2 15.9 13.6 7.2 20.2 17.4 11.5 18.5 22.7 9.6 20.1 12.8 23.1 22.5 11.9 18.2 15.5 12.0 12.9 13.6 15.5 8.7 11.0 13.7 14.0 18.4 14.3 11.0 18.9 17.4 6.6 17.9 9.9 15.0 12.7 18.7 2.3 7.9 0.8 7.0 7.0 5.1 2.5 6.0 16.6 3.6 8.5 7.8 20.7 5.0 16.5 13.2 9.6 9.4 3.3 11.1 2.1 7.0 9.1 17.0 16.6 5.8 8.9 9.5 3.5 7.5 5.7 14.5 12.0 8.8 5.0 4.0 14.9 6.1 9.6 14.9 15.0 11.7 5.9 7.4 9.7 9.9 7.3 1.9 8.3 5.8 2.4 15.0 2.8 5.8 8.4 15.3 3.5 3.7 5.3 15.6 6.5 5.9 3.1 6.8 3.3 16.3 11.2 13.7 8.7 19.3 2.5 1.1 2.0 19.3 4.3 21.9 0.0 5.0 0.8 5.1 7.0 3.4 2.3 2.5 3.0 7.9 2.2 3.9 1.4 0.0 7.0 3.2 4.3 1.1 2.5 13.5 17.1 10.4 16.5 13.6 7.2 22.7 9.6 18.2 17.4 3.0 6.7 3.2 5.1 4.6 3.0 7.5 5.1 26.8 5.7 3.5 2.0 10.8 6.6 6.2 6.8 6.7 2.0 0.0 2.1 9.5 9.7 2.6 13.9 13.1 7.1 1.6 2.9 11.1 3.5 6.8 17.8 3.0 3.3 0.0 3.6 4.0 4.2 0.0 11.3 31.2 2.1 12.9 9.2 13.4 5.1 3.0 4.1 3.9 3.1 0.9 LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 31.3" "Cell type enriched" "Detected in many" 6 "granulocytes: 332.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.5;eosinophil: 31.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 31.3" "Cell line enriched" "Detected in some" 10 "HMC-1: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" 9.0 6.7 3.5 2.8 3.5 8.6 4.6 1.7 5.0 6.9 5.0 9.4 5.4 3.6 8.7 10.4 4.2 13.0 15.7 11.3 3.9 3.1 6.2 2.3 28.3 8.0 6.8 4.2 5.8 2.4 2.0 3.2 2.9 4.3 5.6 1.9 3.3 7.4 11.6 2.7 3.5 5.7 4.5 6.3 6.7 5.0 3.3 3.9 0.8 5.3 5.6 3.2 3.6 3.9 0.1 4.5 31.3 0.3 2.2 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.4 5.3 0.0 0.2 0.2 0.3 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 8.5 0.2 31.3 0.5 0.3 1.7 0.1 1.2 0.8 4.5 0.1 0.2 0.5 0.1 2.2 0.0 0.2 0.1 0.3 3.5 3.5 1.7 5.0 3.9 3.1 6.8 4.2 4.3 3.9 0.0 5.6 2.2 7.5 8.9 0.2 0.0 12.7 4.0 3.4 14.0 0.0 6.9 1.7 4.1 0.3 11.3 0.4 0.0 2.1 1.5 4.7 3.1 332.3 0.8 33.8 0.0 2.9 53.4 8.9 0.0 15.3 23.5 1.7 1.0 1.6 0.0 2.1 0.0 44.6 40.2 0.3 0.0 0.9 0.0 0.7 6.0 2.5 5.0 2.6 5.0 MLYCD "hMCD, MCD" ENSG00000103150 "Malonyl-CoA decarboxylase" O95822 16 83899126-83927026 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 39.1" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 72.8;Cone photoreceptor cells: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" HPA031625 Enhanced NA NA "HPA031625: AB_10602028" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (6.23e-2)" "unprognostic (1.84e-4)" "unprognostic (2.33e-1)" "prognostic favorable (2.61e-7)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.56e-2)" "unprognostic (1.51e-3)" 6.6 10.1 3.3 3.7 4.2 2.3 4.6 2.4 5.4 4.1 6.9 6.3 6.2 4.6 4.4 4.4 5.1 4.9 7.0 39.1 3.7 3.3 6.7 17.4 4.1 3.6 6.9 3.1 6.2 21.5 6.9 5.1 3.1 4.6 5.6 4.4 8.0 6.4 4.1 31.0 4.0 5.1 5.8 3.3 3.8 6.7 7.1 5.7 3.3 5.6 5.7 4.6 6.4 5.4 0.7 0.7 2.3 0.8 0.1 0.9 0.2 0.5 2.3 1.6 2.7 5.0 2.4 3.7 1.2 1.8 1.1 0.5 2.3 1.7 0.4 2.8 2.1 2.1 2.5 2.8 0.8 1.0 1.9 2.1 1.7 0.9 1.4 2.8 1.5 3.2 3.0 2.8 0.7 1.1 1.9 1.2 2.3 2.1 0.8 1.3 4.4 1.5 4.5 2.0 2.2 1.0 3.5 1.4 2.2 3.0 2.7 2.5 2.3 4.5 0.7 2.1 2.5 4.3 1.9 1.6 1.8 0.4 1.4 0.5 2.7 2.6 3.2 1.8 2.1 1.9 0.8 0.7 2.3 0.5 0.5 0.3 0.7 0.8 0.7 0.7 0.3 0.8 0.9 0.3 0.1 0.8 0.3 0.0 0.2 3.3 4.2 2.4 5.4 3.7 3.3 6.9 3.1 4.6 5.7 6.0 5.3 15.6 6.1 1.8 25.1 72.8 20.4 0.0 7.9 22.7 117.8 16.1 26.6 5.6 3.6 6.7 14.8 0.0 4.7 8.7 5.6 8.5 5.7 35.5 10.9 15.9 9.8 9.2 5.6 4.7 13.6 6.9 3.3 1.8 15.8 17.7 5.9 10.5 18.4 18.0 48.9 6.5 7.2 10.5 12.4 1.8 6.9 9.2 16.6 6.8 MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 14 "Cytotrophoblasts: 23.5;Hepatocytes: 33.6;Sertoli cells: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.5" "Group enriched" "Detected in many" 9 "NK-cells: 1.5;T-cells: 2.9" "Cell line enhanced" "Detected in many" "CACO-2: 23.6;JURKAT: 30.1" "Low region specificity" "Detected in all" "HPA045783, HPA058177, HPA075505" Uncertain Enhanced Cytosol NA NA Cytosol "HPA045783: AB_10960058, HPA058177: AB_2683629, HPA075505: AB_2686751" "unprognostic (1.22e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (3.26e-2)" "unprognostic (1.44e-1)" "unprognostic (9.03e-2)" "unprognostic (1.99e-1)" "unprognostic (2.61e-2)" "unprognostic (4.85e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (6.07e-5)" "unprognostic (5.34e-3)" "unprognostic (1.21e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" 26.6 9.6 4.6 5.3 7.9 0.2 27.1 5.9 8.7 6.4 17.5 10.5 5.0 15.4 10.1 8.7 6.9 7.9 8.0 18.0 6.2 2.3 17.5 34.9 19.6 9.2 9.5 6.2 9.0 10.9 4.5 6.3 30.2 7.0 6.7 5.2 11.2 5.9 7.6 19.9 7.1 13.1 8.9 7.1 3.5 6.5 4.0 7.6 0.2 15.4 5.9 3.1 9.7 7.7 0.0 0.1 0.0 0.2 1.5 2.9 0.8 0.0 1.2 4.4 7.1 12.1 4.6 9.0 4.9 8.9 7.0 6.4 23.6 0.1 0.0 5.1 4.8 4.5 0.3 5.3 5.9 5.4 0.0 4.9 0.0 0.0 7.5 7.7 0.0 1.9 8.1 2.2 4.9 2.6 4.3 6.0 30.1 4.8 0.4 7.1 3.0 9.2 0.0 4.1 0.0 2.6 0.0 3.4 0.7 4.3 4.6 3.6 4.7 0.0 2.9 4.1 3.7 3.1 0.8 9.3 7.0 6.1 4.6 2.5 0.0 0.9 0.0 0.8 0.0 2.5 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.6 0.5 0.1 0.0 2.9 2.5 0.0 1.5 0.2 0.0 0.0 0.8 4.6 7.9 5.9 8.7 6.2 2.3 9.5 6.2 7.0 7.6 6.0 1.0 0.0 0.5 0.6 0.8 10.1 7.6 0.0 0.0 8.7 11.8 23.5 5.0 3.4 0.6 2.8 6.4 0.0 3.7 1.2 2.9 0.2 1.1 33.6 2.5 3.2 0.0 2.5 2.8 0.6 3.4 0.0 1.7 0.0 2.9 4.2 1.1 4.8 2.8 12.2 2.2 77.6 15.6 1.4 1.5 1.0 5.1 0.0 4.1 0.3 MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 30000 Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" 11.9 18.5 15.8 16.9 19.7 7.6 12.5 21.7 27.9 10.8 19.4 17.1 10.8 39.6 8.4 7.3 30.0 7.4 8.7 11.9 17.2 18.2 9.2 25.9 14.6 12.6 14.6 17.3 11.1 19.0 11.0 7.8 7.6 24.5 13.7 5.1 10.8 16.1 8.7 27.8 18.3 20.7 6.6 23.8 11.1 21.2 23.0 14.6 4.3 9.2 18.6 12.2 7.3 13.8 15.0 17.6 2.5 8.9 18.1 18.1 9.4 14.7 9.5 15.9 10.3 5.4 11.9 9.0 7.3 7.7 5.0 4.3 25.1 37.5 7.1 11.9 4.3 18.6 22.0 7.1 39.0 1.4 4.5 12.1 5.2 5.2 38.1 10.9 3.3 3.7 9.4 7.5 13.3 4.2 2.5 5.3 17.5 14.6 3.9 2.7 34.5 11.3 17.0 19.1 5.1 9.3 11.8 4.6 18.5 14.8 9.3 16.1 5.4 18.3 4.2 5.3 3.4 20.8 15.0 11.5 4.7 9.5 8.3 4.1 11.0 4.8 24.4 5.6 16.4 7.7 2.5 8.2 1.5 18.1 8.6 13.5 10.3 12.1 11.9 9.5 15.0 9.4 11.5 1.1 18.1 8.9 17.6 12.6 9.4 15.8 19.7 21.7 27.9 17.2 18.2 14.6 17.3 24.5 14.6 23.8 45.3 22.0 10.8 13.5 19.2 11.9 28.1 10.7 15.9 19.2 5.9 20.1 21.6 27.8 48.8 12.0 73.8 0.0 53.8 25.2 18.8 15.9 16.1 17.8 31.6 22.3 31.6 23.9 28.8 70.6 7.5 16.4 20.3 45.9 40.3 14.8 24.2 38.6 8.5 16.5 16.5 6.5 14.2 32.0 13.5 18.9 40.8 32.0 29.4 16.7 NAXD "CARKD, FLJ10769, LP3298" ENSG00000213995 "NAD(P)HX dehydratase" Q8IW45 13 110615460-110639993 "Enzymes, Predicted intracellular proteins" Lyase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 28.5;Distal tubular cells: 33.2;Extravillous trophoblasts: 22.2;Syncytiotrophoblasts: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010551 Uncertain NA NA 230000 "HPA010551: AB_1848669" "unprognostic (1.24e-1)" "unprognostic (5.14e-2)" "unprognostic (1.79e-2)" "prognostic favorable (3.15e-4)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (3.48e-2)" "unprognostic (2.89e-1)" "unprognostic (3.20e-1)" "unprognostic (9.01e-2)" "unprognostic (1.94e-2)" "unprognostic (4.36e-3)" "prognostic favorable (4.63e-5)" "unprognostic (2.19e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.62e-2)" 9.1 22.8 17.3 10.9 20.5 4.6 12.5 20.4 25.0 11.5 17.2 19.0 18.0 11.6 13.9 15.3 16.3 14.0 13.6 14.7 20.9 12.0 14.3 30.4 12.1 11.7 15.0 19.4 28.8 24.8 12.7 15.2 14.7 14.8 16.5 12.4 12.7 12.7 21.2 15.1 20.8 12.6 13.7 13.8 13.2 16.7 17.9 17.0 9.2 15.5 10.5 9.9 12.7 11.8 7.3 7.6 0.7 6.9 6.2 8.5 6.1 10.9 5.0 8.3 6.4 10.8 6.6 14.3 8.5 8.0 9.3 9.6 17.1 11.3 2.0 9.3 6.6 8.0 9.1 4.7 8.9 4.5 8.3 10.5 7.1 15.7 9.5 10.5 9.4 6.7 9.3 16.5 5.9 6.6 10.6 9.8 9.1 6.0 0.1 7.3 11.9 6.9 17.9 7.5 19.6 6.1 2.3 3.2 2.5 9.9 9.4 14.5 8.6 4.9 26.3 5.9 5.7 12.0 15.7 5.7 6.3 5.2 0.1 6.7 7.7 5.2 0.1 10.1 2.1 8.2 0.0 5.9 0.5 8.5 6.9 5.4 7.3 7.7 7.6 7.4 6.5 8.3 8.2 0.7 6.2 4.5 7.6 8.4 6.1 17.3 20.5 20.4 25.0 20.9 12.0 15.0 19.4 14.8 17.0 17.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 16.0 18.2 21.0 0.0 28.5 33.2 12.7 0.0 0.0 0.0 0.0 10.3 22.2 0.0 0.0 1.1 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 18.0 0.0 0.0 10.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.0 NEIL1 "FLJ22402, FPG1, hFPG1, NEI1" ENSG00000140398 "Nei like DNA glycosylase 1" Q96FI4 15 75346955-75357114 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 4.7;memory B-cell: 4.0;naive B-cell: 6.5;NK-cell: 14.1" "Group enriched" "Detected in many" 12 "B-cells: 6.5;NK-cells: 14.1;T-cells: 4.7" "Cell line enhanced" "Detected in many" "Daudi: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054084 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA054084: AB_2682372" "unprognostic (9.84e-3)" "unprognostic (1.19e-1)" "unprognostic (1.15e-2)" "unprognostic (4.62e-3)" "unprognostic (3.21e-2)" "unprognostic (1.81e-2)" "unprognostic (2.24e-2)" "unprognostic (1.17e-3)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.50e-3)" "unprognostic (8.60e-2)" "unprognostic (9.24e-2)" "unprognostic (2.05e-1)" "unprognostic (3.03e-1)" "unprognostic (2.27e-3)" 7.1 14.8 12.9 28.2 14.5 6.8 9.3 24.4 15.4 10.8 8.3 4.9 23.2 10.1 8.4 11.6 6.4 10.0 10.2 5.3 12.8 5.7 7.9 9.1 9.3 9.8 6.0 9.8 11.0 10.8 9.1 9.0 4.6 8.0 10.4 2.4 7.1 25.0 24.2 13.6 11.7 9.5 4.3 5.9 6.8 9.9 3.8 7.0 15.4 8.2 5.2 13.3 7.5 8.5 6.5 0.2 0.7 0.5 14.1 4.7 1.0 2.2 3.7 2.4 1.5 0.7 0.8 4.6 1.3 0.0 0.5 0.1 0.6 4.0 11.6 2.2 0.2 1.1 6.4 1.4 0.4 0.0 5.6 9.5 1.9 10.0 1.8 1.0 2.2 2.7 0.3 1.8 0.6 0.0 6.0 1.5 1.1 1.2 3.4 0.4 2.9 0.4 6.3 2.1 0.4 0.9 2.2 1.5 0.5 2.2 2.4 1.4 2.8 2.3 1.0 3.2 1.3 4.3 3.3 6.3 1.3 2.5 1.9 1.1 5.4 5.2 9.4 1.2 9.4 1.2 0.0 0.5 0.0 4.7 0.1 1.3 4.0 0.8 1.0 0.2 6.5 1.4 1.4 0.7 14.1 0.1 0.2 0.2 1.0 12.9 14.5 24.4 15.4 12.8 5.7 6.0 9.8 8.0 7.0 20.8 19.2 9.3 14.9 5.7 20.2 2.5 2.5 38.8 23.9 14.0 9.8 8.7 1.7 7.2 21.8 13.4 15.5 0.0 7.4 3.1 7.8 12.0 10.5 10.5 2.8 9.5 20.7 24.5 6.9 1.1 17.5 5.8 8.5 0.0 18.2 21.4 6.1 14.7 12.7 5.8 5.9 6.5 4.1 1.4 0.7 5.1 4.0 13.1 11.3 5.8 NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787346 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA073029: AB_2732216, HPA073916: AB_2732245" "unprognostic (1.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (9.88e-2)" "unprognostic (2.18e-2)" "unprognostic (5.72e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (5.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (4.05e-1)" 10.2 21.8 18.7 6.8 17.7 2.7 10.3 11.8 20.9 11.3 5.6 9.0 7.0 3.6 9.9 15.4 6.5 17.9 6.9 14.2 15.4 20.0 9.3 11.0 7.7 8.4 18.4 16.1 12.6 10.9 7.8 13.2 7.6 20.3 10.5 6.1 9.7 11.5 10.3 24.7 18.1 4.6 10.2 12.3 9.5 5.1 26.8 13.3 1.8 15.5 7.1 7.9 7.4 15.8 14.7 5.5 0.8 2.5 9.1 13.6 4.7 4.9 14.0 8.8 17.2 4.2 7.9 3.9 7.9 6.6 7.7 5.3 4.3 5.5 1.9 3.1 9.5 16.6 4.4 8.4 8.7 10.6 5.8 4.2 6.8 3.3 8.4 3.4 2.9 5.1 6.9 12.9 6.7 6.2 7.5 7.2 2.3 9.6 6.7 9.1 5.2 0.5 3.1 7.9 20.5 7.5 8.7 11.3 5.3 9.0 7.5 13.6 10.7 6.2 3.3 11.3 7.4 5.2 0.5 8.8 8.8 12.7 2.3 11.1 6.3 13.1 3.5 23.2 10.2 17.8 0.4 1.5 0.1 9.1 2.5 12.1 14.7 9.3 10.8 3.0 11.4 13.6 12.0 0.8 9.1 1.1 5.5 5.8 4.7 18.7 17.7 11.8 19.8 15.4 20.0 18.4 16.1 20.3 13.3 0.0 4.3 12.6 14.3 7.6 25.6 17.8 17.8 5.3 6.8 7.0 15.7 15.6 28.2 17.4 0.8 9.3 0.9 0.0 20.5 13.6 10.8 15.1 2.3 21.2 12.1 7.9 9.7 7.4 4.7 2.1 13.0 6.6 13.5 10.0 4.5 27.9 14.2 0.0 23.0 24.7 13.2 6.5 13.2 14.2 45.1 11.2 4.5 7.2 5.0 9.1 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309836-177362943 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 70.8" "Cell type enhanced" "Detected in some" 8 "Club cells: 2.3;Extravillous trophoblasts: 2.9;Kupffer cells: 2.2;Spermatocytes: 1.9;Spermatogonia: 3.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 26.6;HL-60: 29.0;Karpas-707: 38.1;MOLT-4: 29.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065761 Enhanced Nucleoplasm NA Yes Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.5 0.4 0.2 7.4 0.2 9.3 0.7 0.1 0.2 0.8 1.5 0.1 0.1 1.5 0.5 0.1 5.6 0.2 0.3 0.5 0.2 0.2 0.4 0.4 0.9 5.1 0.2 0.1 0.3 0.2 0.0 0.2 1.6 0.2 0.2 2.1 0.2 0.8 0.1 0.2 3.4 1.7 0.5 0.7 1.5 0.8 3.5 0.3 70.8 0.2 1.1 5.0 0.7 1.3 0.2 0.3 0.8 0.0 1.6 1.6 0.2 7.1 5.9 6.3 3.1 0.7 1.3 3.1 8.8 3.3 9.8 5.8 2.1 6.3 7.9 1.3 2.3 9.7 3.3 6.6 3.5 14.3 26.6 4.3 5.4 4.7 5.6 0.2 29.0 3.7 0.1 0.2 10.1 2.2 2.0 3.7 20.5 5.6 38.1 6.3 3.1 29.3 11.1 2.9 2.1 4.4 6.0 4.3 2.5 2.5 0.9 5.0 3.4 4.4 5.1 2.4 2.9 4.2 7.6 1.7 5.9 4.6 3.0 8.9 2.6 1.7 12.5 3.9 10.3 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.2 0.0 1.1 0.8 1.6 0.0 0.3 1.6 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.6 2.2 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.9 3.0 1.1 0.2 0.5 0.4 0.1 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 76.0" "Cell type enhanced" "Detected in many" 18 "Cytotrophoblasts: 103.5;Hofbauer cells: 387.9;Ito cells: 109.2;Kupffer cells: 121.2;Syncytiotrophoblasts: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 76.0" "Group enriched" "Detected in many" 36 "granulocytes: 76.0;monocytes: 23.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 14.9 6.8 10.9 14.2 12.3 12.4 5.3 3.5 10.2 3.9 5.3 15.0 11.4 2.4 2.5 23.7 8.0 4.1 10.1 4.7 9.2 8.7 37.4 15.4 14.3 20.4 16.0 8.6 2.8 3.2 2.5 2.5 32.9 15.4 4.4 7.4 3.9 5.7 5.8 2.4 6.5 4.8 5.8 15.3 32.1 4.0 4.0 14.4 3.1 3.4 1.3 10.9 11.8 5.5 0.7 1.3 76.0 23.6 0.0 1.3 10.3 2.7 0.5 0.8 0.0 2.4 2.4 0.7 0.9 1.8 1.0 0.5 0.0 1.2 7.3 1.3 0.0 0.0 1.1 1.6 2.0 0.2 0.0 1.2 11.6 0.3 0.1 1.3 4.4 7.0 1.9 7.8 0.2 0.0 0.1 0.1 8.5 8.7 11.7 1.8 0.9 0.2 2.9 9.3 5.7 0.9 1.1 0.6 8.9 0.2 6.1 2.6 3.9 4.2 0.2 3.7 0.9 2.4 7.1 0.2 1.0 2.0 0.6 0.1 8.4 10.1 7.4 2.1 7.8 3.0 3.6 23.6 18.0 1.0 20.8 0.9 0.3 0.8 0.9 1.3 0.7 0.7 0.9 76.0 0.0 16.0 0.2 1.3 10.3 10.9 12.3 3.5 10.2 9.2 8.7 16.0 8.6 15.4 14.4 0.0 5.6 9.1 4.0 5.5 5.1 2.5 2.5 0.0 1.2 7.0 2.0 103.5 16.6 1.0 14.0 2.1 1.3 23.3 2.1 6.6 3.3 1.2 5.7 2.4 387.9 6.4 1.7 109.2 121.2 20.9 0.9 25.3 10.1 21.6 1.1 2.4 1.4 0.0 0.4 55.2 2.4 0.0 2.9 8.6 8.3 6.1 89.7 3.5 0.8 3.9 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678637-153693992 "Enzymes, FDA approved drug targets, Predicted membrane proteins" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 98.4" "Cell type enriched" "Detected in many" 10 "Ito cells: 136.2" "Cancer enhanced" "Detected in all" "ovarian cancer: 39.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 60.5" "Region enriched" "Detected in many" 5 "olfactory region: 23.0" "Region enhanced" "Detected in single" "olfactory region: 11.1" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 41.1 4.3 0.5 5.9 0.9 0.1 98.4 0.5 0.8 8.1 8.2 0.3 7.3 1.2 16.8 11.1 8.7 25.0 9.3 19.6 0.9 0.5 28.7 3.7 34.8 8.6 0.7 0.0 19.5 4.2 7.8 4.5 11.8 2.5 4.9 1.5 2.0 2.0 9.0 6.9 3.4 4.6 15.6 2.2 1.2 5.0 6.4 0.2 0.8 7.6 5.1 1.1 11.6 26.5 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 60.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.0 0.0 7.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.7 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.5 0.8 0.9 0.5 0.7 0.0 2.5 0.2 0.0 5.8 0.0 0.4 1.3 0.0 4.8 5.1 0.0 0.0 14.0 0.0 0.1 0.0 0.6 8.0 14.2 0.0 0.0 0.0 0.9 3.9 0.4 0.0 1.5 0.2 0.0 0.0 136.2 6.0 7.9 9.5 0.0 0.0 9.0 0.0 0.0 0.7 0.0 3.9 2.8 0.0 0.0 0.9 0.2 0.1 0.9 0.6 0.0 0.0 0.0 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35792154-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 8.6;Muller glia cells: 8.2;Peritubular cells: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.1;T-cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 27.6;ASC TERT1: 20.6;BJ hTERT+: 16.8;HSkMC: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 9.0 4.8 3.8 1.9 6.4 0.0 7.2 32.7 11.2 29.2 7.8 1.8 4.4 1.8 22.6 9.8 5.3 7.6 5.7 7.6 3.7 4.2 3.7 8.4 4.7 2.3 2.5 5.1 8.0 1.3 2.7 7.9 7.1 11.8 8.3 4.0 8.3 3.3 9.5 7.7 6.2 3.7 17.1 3.9 2.6 4.5 5.5 4.0 0.9 3.2 2.4 2.0 6.2 8.9 0.4 3.1 0.0 0.0 0.1 2.1 0.1 0.0 1.6 1.9 0.0 27.6 20.6 1.2 7.7 16.8 6.2 6.7 4.0 2.7 1.1 2.0 15.0 11.6 0.7 2.3 0.2 5.6 1.3 0.7 1.0 1.8 2.0 15.0 0.1 0.0 20.4 1.1 6.9 0.5 6.1 10.1 1.7 0.5 0.1 11.6 0.5 0.3 0.4 2.6 0.8 2.8 1.3 0.1 0.5 1.0 0.8 0.5 0.6 0.2 0.0 0.3 3.1 0.1 0.0 6.5 6.6 5.1 2.1 0.7 0.2 0.3 3.0 8.4 0.3 3.7 0.0 0.0 0.0 1.1 0.0 0.0 0.4 1.2 0.6 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.1 2.1 0.1 3.8 6.4 32.7 11.2 3.7 4.2 2.5 5.1 11.8 4.0 3.0 4.3 0.0 0.6 1.0 4.0 0.6 0.0 1.4 0.0 0.0 2.0 0.3 0.0 0.4 0.1 2.3 0.1 0.0 0.7 0.1 5.7 1.7 1.1 5.7 0.3 3.2 0.0 2.5 0.3 0.0 8.6 0.0 0.0 0.0 0.9 8.2 0.5 3.1 7.4 0.6 2.1 0.0 1.9 2.8 2.0 1.4 0.2 0.0 1.0 0.3 NTHL1 "NTH1, OCTS3" ENSG00000065057 "Nth like DNA glycosylase 1" P78549 16 2039815-2047866 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 755.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025152 Supported NA NA "CAB025152: " "unprognostic (1.06e-1)" "unprognostic (9.71e-2)" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (7.89e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-1)" "unprognostic (2.46e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.53e-2)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (5.08e-2)" "unprognostic (1.62e-2)" 10.5 8.2 13.4 10.5 19.9 6.0 7.8 15.6 17.9 14.8 12.3 9.0 15.1 9.7 11.8 6.9 9.4 20.5 14.7 10.6 12.5 12.1 7.4 17.5 11.1 10.4 13.6 15.7 18.8 24.6 5.8 8.7 8.3 13.3 9.8 8.2 9.1 22.2 18.2 12.4 6.3 11.2 7.8 10.4 15.2 11.1 6.4 11.6 9.6 9.5 6.6 8.4 7.8 9.3 21.4 14.7 2.4 14.2 9.7 18.8 8.5 10.8 26.7 7.8 11.8 3.2 6.1 8.7 4.5 4.9 8.7 5.5 19.0 10.6 23.2 9.6 3.8 5.7 9.8 9.6 10.7 1.5 10.7 23.6 7.2 17.0 21.1 4.4 8.2 8.5 5.1 5.5 4.6 5.0 5.8 12.1 14.3 7.8 8.4 3.4 12.1 12.2 30.8 17.3 13.5 17.5 29.4 8.2 37.3 6.2 3.9 16.6 16.5 5.0 15.3 8.8 3.0 11.0 8.1 4.7 7.4 8.2 6.6 8.5 11.5 13.4 9.4 3.3 11.5 9.2 2.4 8.7 2.0 8.8 14.2 9.8 21.4 10.5 9.8 14.7 17.1 7.8 9.5 0.3 9.7 12.1 14.6 18.8 8.5 13.4 19.9 15.6 17.9 12.5 12.1 13.6 15.7 13.3 11.6 26.8 28.0 7.5 16.5 7.7 8.8 9.8 48.4 16.0 15.9 3.5 0.0 9.0 14.9 15.3 7.6 35.9 21.6 0.0 8.0 14.8 13.9 8.1 5.7 755.9 11.6 6.4 64.8 43.0 19.9 16.6 31.4 11.7 20.3 6.4 53.2 10.1 11.3 40.7 23.7 22.5 6.0 12.9 18.9 5.8 30.9 8.8 2.3 9.2 42.8 19.7 ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448504 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 459.5;Late spermatids: 626.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996" Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "CAB035996: , HPA001536: AB_1079521" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (7.25e-3)" "unprognostic (5.21e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (6.27e-2)" "unprognostic (3.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.67e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-2)" "unprognostic (5.86e-2)" 13.2 8.2 11.6 33.5 11.1 41.8 9.1 7.2 11.8 11.7 17.4 11.5 33.8 8.6 22.9 21.6 16.5 16.5 30.0 33.8 9.7 10.6 31.5 48.7 14.2 42.3 11.3 6.5 29.2 48.7 13.4 35.4 6.9 11.2 26.3 20.7 18.2 11.0 27.2 64.2 9.6 14.9 26.2 10.2 20.4 19.2 54.6 6.3 31.0 16.4 19.8 39.6 16.1 14.6 13.4 10.8 2.4 2.4 1.2 4.4 3.0 19.0 15.3 21.3 25.2 3.8 11.4 49.4 27.6 13.6 26.1 12.1 81.2 8.9 100.7 13.8 16.8 25.2 3.5 65.2 31.3 31.8 38.3 27.2 46.0 26.3 49.5 30.9 77.6 11.0 7.6 8.5 59.0 74.1 13.5 20.9 28.1 76.4 32.8 14.4 12.5 76.8 30.6 38.8 26.5 49.9 54.9 66.9 67.9 15.8 14.0 29.8 25.3 34.6 10.6 13.9 17.1 7.1 34.8 14.6 21.2 43.7 27.3 59.1 15.3 46.3 91.6 19.0 51.5 13.0 0.0 1.3 2.4 2.7 2.4 3.2 13.4 3.8 4.4 3.0 11.0 2.7 4.3 0.5 1.2 1.5 10.8 3.8 3.0 11.6 11.1 7.2 11.8 9.7 10.6 11.3 6.5 11.2 6.3 41.7 217.2 112.6 112.8 51.5 34.5 48.8 71.4 25.4 36.4 38.4 29.5 1.0 61.3 55.5 459.5 35.3 38.6 0.0 23.5 53.1 21.2 276.8 57.7 46.1 43.4 6.4 260.2 11.6 30.9 626.4 14.4 29.0 21.9 12.6 143.2 85.1 24.6 48.9 10.6 101.8 62.6 0.0 40.8 91.4 74.0 76.5 2.9 37.6 120.9 94.9 OGG1 "HMMH, HOGG1, MUTM, OGH1" ENSG00000114026 "8-oxoguanine DNA glycosylase" O15527 3 9749944-9788219 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 65.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027514, CAB047301" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "CAB047301: , HPA027514: AB_10602189" "unprognostic (6.95e-2)" "unprognostic (7.82e-3)" "unprognostic (7.19e-2)" "unprognostic (1.24e-3)" "unprognostic (9.69e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (7.83e-2)" "unprognostic (2.45e-2)" "unprognostic (3.43e-3)" "unprognostic (9.66e-3)" "unprognostic (4.23e-2)" "prognostic favorable (2.65e-4)" "unprognostic (2.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.59e-1)" 10.4 12.9 15.4 28.5 16.2 12.7 11.5 22.0 17.7 16.7 18.8 16.2 10.5 22.0 16.2 13.1 10.0 14.7 12.1 10.7 14.7 10.8 30.1 17.8 9.9 28.5 12.3 14.1 22.5 12.0 5.8 10.2 10.3 15.3 14.4 10.2 14.6 14.3 13.2 7.4 11.5 28.2 12.1 13.6 14.1 10.8 7.3 15.6 19.8 12.2 6.3 25.5 12.2 13.3 12.2 11.9 15.4 8.5 19.4 15.4 8.3 5.7 10.8 10.9 6.8 10.7 12.3 20.2 7.5 7.8 11.6 13.9 10.3 5.7 35.2 5.0 9.5 18.5 5.6 6.4 8.2 4.9 12.5 9.2 17.5 17.4 14.8 11.3 6.8 11.2 12.2 10.6 20.0 8.5 9.4 14.3 5.0 5.5 5.7 11.0 10.8 5.4 6.7 5.8 5.2 15.5 4.0 7.4 11.4 6.5 2.9 4.9 8.6 9.7 7.9 5.8 5.9 12.4 11.6 9.2 11.8 12.4 9.2 12.3 5.7 8.2 18.1 9.5 19.6 7.2 11.3 8.5 15.4 15.1 6.6 14.6 10.4 13.0 12.3 7.6 12.2 10.2 9.6 2.1 19.4 5.3 11.9 15.4 8.3 15.4 16.2 22.0 17.7 14.7 10.8 12.3 14.1 15.3 15.6 0.0 4.3 24.5 8.6 4.8 19.3 2.0 7.6 4.0 2.3 8.7 33.4 5.4 10.0 7.2 0.6 8.3 10.4 23.3 5.9 8.2 9.7 5.0 2.3 8.5 15.7 7.9 17.2 6.7 6.7 0.9 13.3 8.2 6.8 12.6 7.6 10.3 7.1 10.1 12.7 65.4 29.4 25.8 9.0 8.3 15.3 4.0 3.3 13.8 12.2 4.3 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464579 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Extravillous trophoblasts: 137.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 340000 Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.16e-1)" 15.5 27.1 21.6 20.4 17.4 21.4 29.3 15.8 20.6 17.5 22.5 18.5 18.4 17.2 19.6 12.6 29.0 19.6 11.4 13.4 16.7 22.6 26.5 63.7 11.3 25.6 26.4 19.2 23.3 27.7 26.2 17.9 24.3 29.8 17.5 30.5 13.1 15.7 16.8 23.8 20.0 16.1 19.4 23.5 19.8 12.8 18.3 15.9 44.9 17.8 26.8 33.1 18.7 18.9 13.7 12.8 3.2 6.4 10.9 14.4 6.7 34.3 25.8 53.3 33.0 11.4 25.9 45.9 29.8 21.6 42.8 42.2 40.9 40.9 79.6 34.7 19.9 23.3 21.3 84.1 43.3 73.4 15.9 29.6 43.2 39.5 45.3 21.9 76.8 19.3 21.9 31.4 45.4 34.3 23.7 35.0 45.7 74.5 29.7 36.8 22.9 88.1 38.5 61.1 66.2 32.3 71.6 22.8 52.3 40.5 24.1 57.3 34.3 29.3 41.0 18.0 45.5 27.1 24.6 18.8 33.9 44.4 33.3 60.8 21.0 18.0 83.7 35.7 56.3 37.3 3.2 3.7 0.3 4.1 6.4 11.8 13.7 11.5 7.3 11.4 8.9 14.4 12.1 0.9 10.9 4.8 12.8 8.3 6.7 21.6 17.4 15.8 20.6 16.7 22.6 26.4 19.2 29.8 15.9 20.8 19.3 31.8 57.8 50.4 26.0 20.9 56.0 21.4 31.8 31.4 5.9 117.2 31.5 30.5 45.8 21.6 14.2 46.7 22.8 137.4 35.6 28.6 20.7 68.6 45.7 27.0 23.8 11.6 15.8 6.6 27.6 17.1 16.9 22.6 34.9 13.2 23.3 7.0 21.9 41.1 22.9 0.0 17.9 39.4 47.7 44.2 45.7 16.0 65.0 44.1 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 304.2" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 852.6;Intestinal endocrine cells: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 75.3;fHDF/TERT166: 96.5;hTERT-RPE1: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA 59000000 "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 16.5 24.5 8.2 6.5 16.4 0.8 17.3 6.6 16.5 74.9 14.0 5.4 9.5 5.8 21.3 83.8 11.7 10.6 11.5 304.2 8.8 23.5 13.7 2.1 13.2 5.8 10.0 7.6 17.0 16.4 49.5 18.3 26.3 15.5 13.4 9.5 8.7 53.8 29.4 22.0 8.5 8.5 18.5 4.8 8.9 17.2 7.2 4.6 1.8 21.7 13.2 7.3 15.8 15.3 0.5 2.0 10.1 5.3 16.2 14.1 6.3 14.7 2.2 27.1 12.0 75.3 45.1 10.8 41.8 62.6 12.4 37.8 7.1 19.5 0.0 9.0 96.5 17.5 5.0 1.5 18.4 34.3 1.8 6.1 3.0 8.8 2.3 11.4 0.9 3.3 24.6 7.9 9.1 6.9 78.8 25.5 1.2 0.1 2.0 35.1 3.0 0.0 0.4 4.8 2.6 8.1 1.1 15.1 8.1 47.8 1.7 12.8 8.9 17.8 1.1 10.9 16.6 4.6 0.9 19.6 39.4 10.2 18.4 12.4 4.6 1.1 0.0 45.2 4.1 33.9 1.9 5.3 0.1 14.1 0.9 10.0 0.5 8.5 10.4 2.0 0.3 2.9 4.8 10.1 16.2 1.9 1.1 12.1 6.3 8.2 16.4 6.6 16.5 8.8 23.5 10.0 7.6 15.5 4.6 50.6 28.7 3.7 10.4 25.0 10.9 852.6 0.0 10.7 27.3 57.6 2.0 0.7 6.6 11.6 5.0 54.1 6.8 0.0 18.6 37.1 102.7 20.4 9.2 2.4 5.5 7.9 308.8 70.0 12.0 4.7 55.8 6.7 35.4 5.4 12.6 13.0 34.7 2.9 55.2 41.6 2.8 19.4 47.4 1.6 2.1 20.7 5.6 15.3 6.6 13.1 PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888784 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.0" "Cell type enhanced" "Detected in all" 7 "Hepatocytes: 577.2;Proximal tubular cells: 733.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 67.0;Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 210000 Nucleoplasm Cytosol "HPA037575: AB_10671761, HPA061723: AB_2684594" "unprognostic (1.02e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (3.69e-1)" "unprognostic (5.39e-2)" "unprognostic (4.80e-3)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (2.40e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.38e-2)" "unprognostic (9.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.76e-2)" "unprognostic (7.43e-3)" 18.3 25.5 18.1 9.6 15.6 4.3 19.7 13.2 14.8 13.9 18.4 7.8 24.3 12.6 13.9 21.4 26.5 25.6 22.9 32.5 10.8 23.7 38.7 99.0 14.0 7.8 16.7 12.3 18.5 73.0 15.8 15.5 11.7 16.4 26.9 20.3 16.3 16.2 20.7 23.1 5.8 17.2 18.1 14.5 10.2 19.2 7.0 8.7 4.3 36.8 16.2 12.3 22.4 31.8 11.8 20.9 3.5 19.4 8.0 16.9 7.5 20.2 48.2 2.9 29.9 10.9 10.2 3.9 6.6 10.9 10.2 8.2 67.0 36.0 4.1 19.1 7.2 7.9 13.5 18.2 10.5 7.0 10.9 32.8 3.6 7.7 65.8 11.5 3.6 13.5 10.0 11.5 10.1 4.8 15.5 27.4 2.6 7.1 0.3 7.1 33.9 0.4 12.1 4.0 54.9 45.1 1.9 4.0 13.3 42.9 21.0 12.6 21.4 5.4 37.3 14.2 8.4 10.8 7.0 11.3 1.7 14.3 2.5 16.0 0.1 0.8 0.1 9.3 11.8 2.6 0.0 10.7 3.5 8.8 19.4 6.9 11.8 11.6 12.6 20.9 4.1 3.8 7.9 0.6 8.0 13.3 15.3 16.9 7.5 18.1 15.6 13.2 14.8 10.8 23.7 16.7 12.3 16.4 8.7 38.7 59.6 41.0 140.4 44.3 32.7 140.4 142.7 72.3 73.9 177.9 5.9 105.7 384.7 161.2 1.3 33.8 116.6 23.3 147.5 63.7 71.1 169.6 31.1 577.2 160.3 33.4 169.3 32.5 54.4 5.8 62.5 71.4 74.2 90.2 228.3 70.5 157.8 147.3 89.8 733.2 28.5 84.1 57.7 4.9 7.9 40.0 64.9 33.8 199.7 158.3 PCBD2 "DCOH2, DCOHM" ENSG00000132570 "Pterin-4 alpha-carbinolamine dehydratase 2" Q9H0N5 5 134904906-135007959 "Enzymes, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 47.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036428 Uncertain Approved "Plasma membrane" NA NA "Plasma membrane" "HPA036428: AB_10670103" "unprognostic (3.70e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (4.22e-1)" "unprognostic (6.43e-2)" "unprognostic (4.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.57e-2)" "unprognostic (6.34e-2)" "unprognostic (9.32e-3)" "unprognostic (1.50e-1)" 4.9 8.1 5.4 7.0 6.6 6.6 5.3 3.0 4.4 3.9 8.7 6.5 9.4 8.0 6.5 8.4 9.3 4.9 6.9 13.8 5.0 5.3 9.2 9.8 6.5 5.0 5.6 5.2 5.1 12.9 9.6 6.1 4.8 6.8 4.7 6.4 9.6 14.2 7.9 47.0 6.7 12.7 7.6 7.0 5.5 7.1 5.5 5.8 5.3 8.3 13.5 8.1 5.6 5.5 8.2 11.5 7.2 10.1 6.3 6.6 4.3 7.8 7.6 8.1 6.1 5.6 4.8 6.0 6.3 4.9 3.6 3.6 14.2 20.1 9.4 10.6 4.2 7.1 5.3 5.5 6.0 3.3 13.1 3.7 5.3 8.1 8.5 5.4 6.1 3.8 2.6 5.9 3.7 8.7 4.2 4.2 7.3 7.7 14.1 6.3 16.1 6.4 10.4 4.5 10.8 7.4 10.2 7.6 8.3 6.6 6.7 6.1 8.0 9.4 4.9 7.8 7.1 13.7 8.1 4.6 6.9 5.2 6.1 8.0 11.0 15.0 6.4 6.2 7.5 4.5 2.7 10.1 7.2 5.1 6.3 5.0 8.2 6.3 5.3 8.6 8.2 5.4 5.3 3.3 6.3 6.1 11.5 6.6 4.3 5.4 6.6 3.0 4.1 5.0 5.3 5.6 5.2 6.8 5.8 8.9 6.4 4.5 5.6 3.2 12.0 29.7 17.8 10.7 3.4 15.7 11.8 10.5 18.3 14.5 5.4 8.4 17.2 46.7 15.8 21.0 4.9 6.2 5.8 21.7 21.4 22.3 4.1 6.7 5.9 2.5 6.6 9.5 5.0 31.5 8.4 13.5 15.4 3.5 2.1 21.4 46.7 0.0 5.3 5.6 10.4 5.3 8.5 7.5 15.8 7.2 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568112 "Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 419.5" "Cell type enhanced" "Detected in many" 24 "Distal tubular cells: 499.0;Enterocytes: 868.1;Hepatocytes: 756.2;Proximal tubular cells: 2559.6" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "ASC diff: 22.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 380000 "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 10.0 0.1 0.4 2.2 0.4 0.0 11.1 0.2 0.6 0.1 52.0 0.2 0.1 19.2 0.1 0.7 0.2 0.1 5.6 0.4 0.3 0.2 72.0 419.5 0.2 0.3 0.2 0.2 0.4 0.2 0.0 5.0 0.1 0.5 0.2 14.0 0.2 0.2 0.1 0.3 0.1 58.5 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.4 0.4 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.5 0.2 0.0 0.0 9.5 0.0 0.1 0.2 0.3 30.6 0.0 1.2 85.5 0.0 0.0 499.0 0.3 0.0 0.1 868.1 0.0 0.0 0.0 0.2 0.0 9.2 756.2 0.0 3.2 51.8 23.4 17.7 0.0 0.0 0.0 0.0 0.0 182.0 8.0 0.1 241.9 0.0 2559.6 0.2 0.0 2.1 0.0 0.0 0.3 0.2 8.5 181.4 0.0 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 156.3;liver: 115.1" "Cell type enhanced" "Detected in many" 11 "Enterocytes: 152.4;Hepatocytes: 291.7;Proximal tubular cells: 166.4" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 35.3;hTCEpi: 34.3;SK-MEL-30: 32.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3300000 Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 8.2 2.5 1.0 4.9 1.9 1.0 4.3 1.3 1.3 1.3 69.7 1.4 6.9 51.8 1.3 8.5 4.5 1.2 4.2 2.6 1.5 1.0 26.4 115.1 6.0 4.4 1.7 1.2 1.8 8.5 3.4 1.7 1.2 1.8 2.0 5.4 1.9 11.5 4.9 1.0 2.7 156.3 1.1 1.7 6.7 3.3 3.9 1.3 1.3 5.8 1.9 4.6 2.8 1.9 8.8 10.8 2.4 15.1 1.5 6.5 3.9 5.5 3.1 0.9 5.9 3.7 3.7 15.0 6.9 8.3 5.8 9.4 5.1 6.4 14.1 0.8 10.6 1.9 8.1 6.0 8.9 4.8 7.2 0.2 2.5 1.7 27.5 35.3 4.9 11.1 4.3 34.3 3.6 8.9 1.6 4.6 16.4 7.2 26.1 2.2 23.9 1.2 2.5 1.0 12.5 4.2 2.8 3.4 8.0 1.7 8.6 3.7 5.9 5.3 6.8 32.5 0.9 9.2 7.6 0.8 1.2 6.7 1.8 1.9 17.9 5.6 3.5 3.5 7.7 3.1 0.1 8.2 2.4 3.1 15.1 3.4 8.8 3.5 3.5 10.8 6.1 2.2 2.0 1.0 1.5 14.4 1.9 6.5 3.9 1.0 1.9 1.3 1.3 1.5 1.0 1.7 1.2 1.8 1.3 11.9 22.0 24.4 8.8 3.0 4.1 1.2 20.4 2.7 3.4 17.4 0.0 3.4 29.9 17.2 49.9 3.5 152.4 0.0 67.0 11.6 5.3 6.8 1.1 291.7 56.2 0.0 8.7 10.4 15.0 15.5 3.1 14.5 6.8 29.7 43.0 5.6 27.0 63.4 2.8 166.4 5.4 0.0 5.1 8.6 0.9 4.3 2.5 9.6 63.5 11.9 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208497-178232791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 190000 Mitochondria "HPA036461: AB_10670717, HPA063608: AB_2685059" "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavorable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 18.7 13.1 10.5 25.0 10.8 9.8 15.5 8.3 10.9 13.9 24.3 13.4 14.4 15.1 13.5 14.9 10.7 13.6 17.5 15.5 8.9 4.9 18.1 44.4 14.7 16.8 13.7 9.3 13.2 18.0 11.9 11.9 11.8 10.2 12.4 23.9 12.1 12.3 13.7 20.2 7.6 29.8 14.1 10.7 20.2 15.3 16.4 11.7 16.3 16.6 10.5 17.4 14.0 11.8 13.9 32.8 16.7 21.7 10.7 14.0 14.3 5.8 2.4 5.8 2.3 14.7 11.7 8.8 3.7 4.1 4.9 7.9 6.2 7.5 7.6 11.2 11.2 6.2 3.8 5.0 9.4 5.7 15.6 5.0 9.7 9.8 4.4 23.9 5.5 6.3 13.3 9.9 6.2 15.1 10.1 16.3 11.4 7.1 17.7 7.4 8.5 7.7 2.9 1.2 7.3 8.0 5.1 2.8 15.3 8.9 5.3 3.6 3.3 5.8 3.4 6.1 7.1 3.7 4.5 6.6 5.1 4.6 3.3 3.9 11.3 3.1 4.6 1.5 5.9 3.4 6.3 19.5 16.7 10.0 21.7 10.1 13.9 11.3 11.4 25.2 12.6 14.0 11.3 4.4 10.7 21.3 32.8 12.9 14.3 10.5 10.8 8.3 10.9 8.9 4.9 13.7 9.3 10.2 11.7 17.9 14.7 36.2 35.3 9.5 20.4 15.7 33.1 12.0 9.1 22.7 23.6 14.0 16.6 17.9 16.8 22.4 97.5 0.0 16.2 15.1 23.7 24.7 12.7 27.6 27.2 14.3 18.5 22.7 23.8 45.2 39.4 30.7 23.6 63.1 33.9 26.4 14.7 54.6 23.7 31.0 26.5 12.9 16.5 28.6 23.7 9.2 18.4 34.6 33.9 31.3 PISD "dJ858B16.2, PSDC" ENSG00000241878 "Phosphatidylserine decarboxylase" Q9UG56 22 31618491-31662432 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cytotrophoblasts: 177.5;Syncytiotrophoblasts: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 39.6" "Low region specificity" "Detected in all" "HPA031090, HPA031091" Approved Approved "Golgi apparatus,Cytosol" NA NA "Golgi apparatus, Cytosol" "HPA031090: AB_10600114, HPA031091: AB_10600893" "unprognostic (7.96e-2)" "unprognostic (5.41e-3)" "unprognostic (2.60e-1)" "unprognostic (8.31e-2)" "unprognostic (5.61e-2)" "unprognostic (4.55e-3)" "unprognostic (2.44e-3)" "unprognostic (8.13e-3)" "unprognostic (6.37e-3)" "unprognostic (1.23e-1)" "unprognostic (1.11e-3)" "unprognostic (1.70e-2)" "unprognostic (4.18e-3)" "unprognostic (1.91e-2)" "unprognostic (4.85e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.27e-5)" 38.3 12.3 9.5 15.1 10.9 20.9 18.5 34.5 12.3 5.9 7.3 6.2 7.4 11.4 9.6 14.4 7.0 10.0 9.5 6.9 6.4 6.9 11.9 8.4 12.9 14.6 8.3 10.1 7.5 10.9 6.0 11.7 38.1 8.6 8.2 3.3 7.7 7.9 7.9 6.4 10.2 8.0 6.2 5.8 16.5 9.7 17.8 7.7 4.2 10.6 5.3 9.8 6.2 7.0 6.9 11.0 28.6 12.9 5.7 6.8 7.9 10.5 9.8 3.0 2.9 9.0 3.5 6.8 8.7 6.9 6.1 6.6 14.1 3.3 6.4 9.3 4.4 8.1 12.0 4.0 7.7 1.0 7.0 8.5 6.7 5.9 11.6 18.8 13.9 17.5 6.5 4.4 10.8 4.7 2.5 5.3 4.5 19.3 3.8 3.4 39.6 6.0 6.0 2.9 7.0 4.1 8.5 3.3 6.4 3.9 9.4 7.3 4.3 5.0 16.3 5.6 2.5 13.4 7.6 10.4 7.7 9.2 4.9 8.0 4.5 6.3 7.9 7.3 9.4 6.1 9.9 12.9 9.3 6.8 9.5 6.5 6.9 4.9 5.7 11.0 6.3 6.7 5.5 28.6 5.7 5.0 5.4 4.7 7.9 9.5 10.9 34.5 12.3 6.4 6.9 8.3 10.1 8.6 7.7 14.9 14.1 13.5 30.6 22.8 22.8 39.5 12.7 4.0 27.3 40.1 19.6 177.5 10.0 26.6 41.3 19.1 11.7 0.0 14.6 14.4 14.5 37.7 17.4 6.6 31.6 17.5 20.1 9.2 32.2 61.8 8.9 19.4 3.3 13.6 11.8 11.0 14.6 8.6 6.7 11.6 25.8 19.4 11.3 16.3 18.1 18.6 204.9 8.7 11.8 36.8 PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023555-75117462 "Enzymes, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.9;granulocytes: 40.4;monocytes: 18.1" "Cell line enhanced" "Detected in all" "Karpas-707: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol NA NA Cytosol "HPA045667: AB_2679412" "unprognostic (8.66e-2)" "unprognostic (1.07e-3)" "unprognostic (6.03e-2)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (6.53e-2)" "unprognostic (1.76e-2)" "unprognostic (8.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.60e-2)" "unprognostic (7.67e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-1)" "unprognostic (2.13e-3)" 10.4 18.5 7.7 11.1 9.3 16.7 14.5 10.8 10.2 8.4 10.8 16.0 15.1 9.4 16.3 13.3 17.5 10.9 12.1 7.8 7.3 7.9 12.5 12.0 13.9 14.0 16.8 5.9 9.2 22.1 14.4 11.3 8.9 11.0 12.0 9.3 15.6 17.5 8.0 10.5 8.3 11.6 6.1 13.6 18.0 10.7 9.7 11.3 7.4 11.0 11.5 16.5 14.2 9.4 4.2 19.9 40.4 18.1 4.5 5.6 4.2 6.0 11.4 4.7 3.7 2.9 2.7 4.1 6.1 2.7 8.3 6.5 6.7 16.5 6.9 11.0 3.0 5.1 6.3 7.7 10.2 4.2 24.3 9.4 12.1 7.1 7.1 8.3 7.0 15.8 3.6 6.8 8.5 13.1 3.3 6.5 10.3 8.1 54.0 5.9 11.7 4.2 10.9 7.6 12.9 5.3 7.1 9.3 14.8 6.2 8.7 11.5 3.3 9.0 12.6 13.2 5.7 15.6 9.1 3.7 8.5 5.9 4.2 10.8 16.5 10.8 11.4 5.2 17.9 9.5 10.9 6.5 40.4 3.4 17.5 5.6 4.2 3.1 3.8 4.9 2.3 3.6 4.3 39.3 4.5 18.1 19.9 3.3 4.2 7.7 9.3 10.8 10.2 7.3 7.9 16.8 5.9 11.0 11.3 14.9 6.9 2.2 6.1 3.4 2.6 3.4 5.1 12.0 3.4 8.7 0.0 14.7 21.6 15.1 0.7 9.8 11.1 0.0 13.4 11.5 7.2 5.7 11.5 4.2 16.7 7.9 4.1 4.9 12.5 2.9 4.0 15.4 13.5 21.6 8.5 3.5 16.2 31.7 4.9 14.9 8.4 6.5 8.2 6.5 16.4 3.4 9.2 13.1 10.0 11.9 PTS PTPS ENSG00000150787 "6-pyruvoyltetrahydropterin synthase" Q03393 11 112226365-112269955 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Disease mutation, Phenylketonuria" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001481 Uncertain Approved Cytosol NA NA Cytosol "HPA001481: AB_1079716" "unprognostic (2.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.66e-3)" "unprognostic (8.38e-3)" "unprognostic (4.58e-1)" "unprognostic (3.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.81e-2)" "unprognostic (2.05e-2)" "unprognostic (8.74e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-2)" "unprognostic (3.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.97e-1)" "unprognostic (1.52e-3)" "unprognostic (1.65e-1)" 6.7 37.1 13.9 6.3 16.6 12.2 13.9 8.9 16.5 10.4 12.7 10.2 6.1 10.7 9.3 20.3 17.9 8.2 14.7 11.6 11.8 28.9 21.9 40.7 5.6 10.4 23.5 14.3 6.7 11.9 12.1 21.5 12.1 18.8 14.9 14.4 9.9 10.9 11.4 11.7 11.5 10.9 12.4 16.8 5.1 18.8 6.7 9.8 3.6 16.3 13.2 7.7 9.3 16.1 6.3 6.8 1.9 5.5 3.4 5.9 2.9 10.4 11.0 12.0 5.1 8.6 10.3 15.9 31.1 14.2 17.1 18.1 24.8 10.5 11.1 23.8 18.2 22.9 15.1 17.0 20.0 18.5 9.0 14.3 2.8 17.0 20.2 27.2 6.8 1.5 17.9 28.3 16.3 19.3 13.2 12.8 9.5 10.6 6.0 10.7 11.5 5.2 9.0 9.0 19.4 21.7 3.5 2.4 15.9 36.6 15.0 13.6 13.7 17.5 17.1 9.7 40.8 12.8 6.1 16.1 16.8 18.3 20.0 24.4 4.2 8.3 26.5 11.6 7.2 17.4 0.9 2.1 1.9 3.8 2.3 3.8 5.5 5.0 4.7 3.6 6.3 3.5 4.5 1.0 3.4 5.5 6.8 5.9 2.9 13.9 16.6 8.9 16.5 11.8 28.9 23.5 14.3 18.8 9.8 17.9 24.5 24.0 66.3 109.0 14.8 83.9 56.0 54.9 21.6 52.4 0.0 48.3 179.1 80.8 4.1 41.9 57.6 23.3 68.2 99.5 46.6 67.1 19.7 115.0 33.0 9.5 76.7 34.4 17.3 6.9 13.6 30.6 25.3 34.3 50.0 26.2 90.3 66.6 24.4 114.8 16.5 25.8 69.5 15.8 93.0 114.6 58.8 33.1 39.6 98.4 RPS3 "FLJ26283, FLJ27450, MGC87870, S3" ENSG00000149273 "Ribosomal protein S3" P23396 11 75399486-75422280 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Lyase, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063339 Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA 430000 "Endoplasmic reticulum, Cytosol" "HPA063339: AB_2684990" "unprognostic (3.62e-2)" "unprognostic (6.94e-3)" "unprognostic (2.64e-1)" "unprognostic (1.44e-2)" "unprognostic (5.55e-2)" "unprognostic (1.08e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-2)" "unprognostic (3.27e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.92e-6)" "unprognostic (3.22e-1)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (2.19e-1)" 72.2 52.7 36.6 108.4 41.2 122.2 136.6 32.1 33.8 105.1 102.0 32.5 65.2 65.8 102.4 84.7 136.5 92.2 107.7 58.5 29.7 26.5 52.9 78.1 71.0 218.6 47.6 30.6 224.7 288.7 13.8 51.3 75.9 35.0 105.7 65.7 47.6 151.0 61.8 86.9 117.6 78.0 110.6 42.1 121.4 75.4 54.1 36.5 126.5 119.4 134.7 130.1 110.3 118.9 104.5 69.7 22.6 44.5 64.6 144.2 213.9 84.0 52.1 74.1 81.7 93.8 167.4 95.9 80.6 103.9 107.1 69.8 150.4 100.7 294.1 98.8 72.4 59.0 121.9 95.7 150.0 98.7 77.8 74.8 120.4 52.0 66.4 140.0 194.4 79.0 196.4 205.0 73.1 203.4 126.2 140.4 131.7 120.0 83.7 96.1 92.3 116.6 93.5 93.1 295.8 61.9 110.8 260.2 214.2 105.1 70.4 63.9 90.6 59.4 141.4 82.0 75.2 144.2 149.0 112.4 51.8 86.3 70.5 72.8 76.9 94.8 325.8 31.1 109.1 52.3 22.6 44.5 14.7 94.2 31.6 129.1 104.5 123.0 99.4 69.7 95.6 144.2 111.8 11.2 64.6 30.1 60.8 78.2 213.9 36.6 41.2 32.1 33.8 29.7 26.5 47.6 30.6 35.0 36.5 866.5 1237.3 4967.7 6162.8 5594.2 395.4 375.5 1814.0 683.9 1733.4 689.2 125.7 5421.9 1850.2 2098.6 348.9 3202.9 1729.9 1308.2 4686.8 7893.8 2767.0 3521.3 1562.3 1179.0 3205.3 125.5 1988.8 2139.1 2727.1 762.5 3476.8 3124.5 2689.2 3452.7 3995.8 368.1 3769.5 2872.2 1695.0 1677.7 343.0 1099.5 3088.9 437.8 578.7 6855.6 4907.0 4548.4 5852.6 6063.3 SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060889-238099413 "Enzymes, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Early spermatids: 82.6;Late spermatids: 106.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020190, HPA055760" Uncertain Enhanced "Golgi apparatus" NA NA 110000 "Golgi apparatus" "HPA020190: , HPA055760: AB_2682910" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (8.65e-5)" "unprognostic (8.96e-2)" "unprognostic (9.85e-3)" "unprognostic (1.14e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-2)" "unprognostic (8.38e-2)" "unprognostic (3.98e-3)" "unprognostic (1.03e-2)" "unprognostic (1.02e-3)" "unprognostic (3.73e-1)" "unprognostic (4.37e-2)" "unprognostic (2.50e-3)" "unprognostic (1.98e-1)" 4.1 3.8 6.0 6.3 7.4 5.3 3.6 10.2 7.4 4.3 6.3 11.1 5.7 9.8 8.4 8.3 4.5 4.6 5.4 6.5 7.3 6.8 9.9 24.1 4.0 6.5 9.6 4.7 6.3 22.7 5.2 5.1 2.6 6.6 5.0 4.3 6.4 4.5 5.6 5.1 2.8 9.6 5.1 9.4 5.6 3.9 15.3 6.1 8.9 8.1 6.3 5.3 4.6 4.0 5.0 5.7 6.9 5.6 4.2 8.1 4.3 5.7 9.7 6.2 16.6 5.0 3.4 12.6 5.8 2.9 6.2 7.6 6.4 4.7 9.6 1.7 3.3 19.9 8.4 24.3 12.4 5.9 10.9 21.8 11.1 13.0 22.0 9.4 9.2 9.6 3.8 6.1 11.6 13.3 2.6 11.5 13.3 19.3 2.7 6.3 8.6 9.1 16.9 20.1 8.0 8.1 10.7 12.0 9.5 5.9 2.0 7.1 15.1 6.4 10.3 10.4 4.8 3.2 13.6 4.9 9.4 6.1 12.4 12.4 6.8 6.2 4.8 5.8 18.7 7.4 2.0 5.3 6.9 4.7 4.3 3.7 5.0 5.7 8.1 5.7 3.5 4.3 4.2 0.9 4.2 5.6 1.2 5.3 4.3 6.0 7.4 10.2 7.4 7.3 6.8 9.6 4.7 6.6 6.1 0.0 0.0 3.7 1.9 1.4 5.3 2.4 0.0 1.4 0.0 0.0 7.9 1.1 3.3 4.4 82.6 2.7 2.1 0.0 3.2 1.4 1.9 1.0 0.0 2.4 3.4 6.4 2.4 1.3 0.0 106.4 2.8 2.0 1.7 2.8 2.6 2.3 2.7 5.8 0.0 1.7 6.1 0.0 1.7 6.0 4.8 1.4 0.6 2.2 2.8 1.4 SDS SDH ENSG00000135094 "Serine dehydratase" P20132 12 113392445-113426301 "Enzymes, Plasma proteins, Predicted intracellular proteins" Gluconeogenesis Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "liver: 276.9" "Group enriched" "Detected in many" 4 "Hepatocytes: 317.5;Hofbauer cells: 211.0;monocytes: 169.5" "Cancer enriched" "Detected in all" 31 "liver cancer: 165.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 10 "myeloid DC: 12.8" "Lineage enriched" "Detected in single" 15 "dendritic cells: 12.8" "Cell line enhanced" "Detected in some" "HMC-1: 5.5;SK-BR-3: 3.4" "Low region specificity" "Detected in single" HPA039230 Uncertain Approved Mitochondria,Cytosol NA NA Cytosol Mitochondria "HPA039230: AB_10674281" "unprognostic (1.31e-1)" "prognostic favorable (5.24e-4)" "unprognostic (6.37e-3)" "unprognostic (6.94e-2)" "unprognostic (9.19e-3)" "unprognostic (2.65e-2)" "unprognostic (2.35e-2)" "unprognostic (8.85e-2)" "unprognostic (1.79e-1)" "unprognostic (2.55e-1)" "unprognostic (4.89e-2)" "unprognostic (3.20e-1)" "unprognostic (4.08e-3)" "unprognostic (2.12e-1)" "unprognostic (2.07e-2)" "unprognostic (4.35e-1)" "unprognostic (2.99e-2)" 0.9 0.9 2.2 1.4 5.9 0.5 0.4 0.6 2.1 0.5 0.9 0.8 0.0 0.7 0.4 0.2 0.2 0.2 1.4 0.2 1.7 2.5 0.2 276.9 0.6 0.6 4.2 0.7 0.3 0.4 0.1 0.0 1.0 2.8 0.3 0.8 1.3 0.3 0.2 0.2 0.2 0.7 0.3 1.3 0.5 0.9 0.3 0.8 0.1 0.3 0.0 0.3 0.8 0.0 0.0 12.8 0.6 0.8 0.2 0.0 0.3 0.0 0.4 0.2 1.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.2 0.4 2.3 0.0 0.3 0.4 0.0 0.0 0.0 0.5 0.5 1.3 0.6 0.6 0.1 0.8 5.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.6 0.0 1.4 0.1 0.4 0.8 0.0 0.9 0.0 0.8 0.1 0.2 0.6 0.1 0.1 1.6 3.4 0.7 0.1 1.2 1.7 0.6 0.0 0.9 1.1 0.3 0.7 0.4 0.2 1.1 0.8 0.3 0.1 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.6 0.2 0.1 1.3 0.0 0.3 2.2 5.9 0.6 1.6 1.7 2.5 4.2 0.7 2.8 0.8 0.0 1.1 21.2 0.2 2.2 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.7 0.0 2.1 0.0 0.3 0.0 23.3 0.3 0.7 0.8 0.2 0.0 317.5 211.0 0.0 0.0 10.4 27.7 0.0 0.0 55.6 1.7 169.5 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 2.8 2.1 3.3 0.0 0.0 SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422237-113438276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.2" "Cell type enhanced" "Detected in many" 9 "Hepatocytes: 118.4;Hofbauer cells: 93.1;monocytes: 174.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 6.5;intermediate monocyte: 7.1;myeloid DC: 13.2;plasmacytoid DC: 12.8" "Group enriched" "Detected in many" 8 "dendritic cells: 13.2;monocytes: 7.1" "Cell line enhanced" "Detected in many" "HMC-1: 22.6;MCF7: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol NA NA Cytosol "HPA005740: AB_10601486" "unprognostic (1.34e-1)" "unprognostic (8.33e-2)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.24e-2)" "unprognostic (6.17e-3)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.00e-2)" "prognostic favorable (8.58e-4)" "unprognostic (2.93e-1)" "prognostic favorable (3.09e-5)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (7.33e-2)" 3.1 15.3 4.2 3.8 5.1 1.4 2.8 1.5 7.1 2.6 7.1 5.5 6.2 10.0 2.5 9.7 1.3 4.6 5.2 7.2 3.6 6.1 15.5 53.2 2.8 2.8 9.5 4.2 4.6 15.3 5.0 7.6 3.1 7.8 4.2 5.0 4.6 4.9 4.5 2.1 0.7 7.8 2.9 8.8 3.0 5.2 7.0 2.6 1.5 20.3 1.3 1.6 4.0 1.5 1.1 13.2 0.3 7.1 1.3 0.2 1.7 3.6 14.2 2.0 6.0 0.4 0.9 1.4 2.1 0.5 2.2 1.9 6.1 3.8 0.2 10.7 3.4 6.2 3.7 0.9 4.8 0.8 8.6 3.6 9.1 3.4 2.6 12.0 1.1 22.6 1.9 6.8 5.5 8.2 2.6 3.3 0.0 7.1 2.8 2.7 38.7 0.0 4.5 2.1 3.9 6.1 0.0 3.0 6.8 5.9 4.4 0.6 0.2 8.8 10.0 8.5 1.9 12.3 10.4 3.0 2.7 5.3 12.1 1.8 0.6 0.5 0.1 11.6 3.7 3.3 0.1 6.5 0.0 0.0 7.1 0.0 1.1 0.0 0.0 13.2 0.1 0.0 0.0 0.3 1.3 0.9 12.8 0.2 1.7 4.2 5.1 1.5 7.1 3.6 6.1 9.5 4.2 7.8 2.6 0.0 6.1 8.6 2.1 0.8 0.2 15.7 25.5 0.0 0.0 27.9 2.0 11.4 66.3 30.4 0.4 2.9 43.5 23.3 17.7 2.6 3.8 6.0 43.8 118.4 93.1 3.2 30.5 4.9 12.3 1.1 2.6 14.9 3.3 174.9 28.9 19.5 17.4 40.3 5.3 76.8 1.5 0.0 5.7 0.0 0.2 0.5 6.1 4.3 25.5 4.3 SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815961-70881173 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" 9.6 11.2 12.0 20.2 11.4 4.9 24.4 10.8 10.6 16.2 17.1 16.0 21.9 13.3 15.5 16.8 26.7 13.5 13.4 8.3 11.3 9.8 18.2 27.1 10.4 20.1 11.9 9.5 10.0 34.6 15.4 10.2 11.3 10.4 16.1 15.6 7.6 15.0 19.5 7.6 28.6 32.5 12.1 15.7 22.9 10.3 15.3 11.0 14.7 17.6 12.8 18.0 21.4 26.8 5.6 9.7 8.9 24.8 10.9 11.5 6.6 10.7 14.4 13.9 15.9 3.8 5.0 9.2 6.3 6.8 6.9 9.0 15.6 23.9 9.7 7.5 6.4 6.7 18.2 11.9 12.8 9.9 15.5 6.4 1.0 7.3 18.6 14.5 4.2 8.8 9.4 21.7 9.3 24.5 14.7 4.3 9.2 2.8 8.5 9.8 11.9 5.1 2.8 6.3 14.3 8.0 6.6 10.6 3.6 11.1 45.7 9.5 11.6 12.7 19.5 11.6 11.4 10.1 3.0 8.3 6.3 16.5 4.8 12.1 3.5 4.8 4.5 6.2 7.8 4.4 0.6 11.5 7.9 11.5 20.3 10.4 4.7 7.5 9.4 9.7 5.6 5.7 9.0 8.9 10.9 24.8 5.4 6.8 6.6 12.0 11.4 10.8 10.4 11.3 9.8 11.9 9.5 10.4 11.0 14.9 5.4 9.9 14.9 10.9 6.5 5.6 30.6 14.7 14.8 43.6 19.6 6.6 3.3 32.5 2.3 6.4 38.8 0.0 33.2 10.9 12.4 23.9 14.9 39.5 25.3 14.3 24.1 6.2 30.2 4.5 10.6 15.9 6.8 16.2 20.8 9.3 41.0 17.3 19.1 11.5 8.2 6.5 11.4 19.9 31.5 19.8 5.3 11.4 16.2 20.4 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 11.6 12.6 17.1 7.7 14.7 13.9 16.7 12.2 24.9 8.4 10.4 13.9 11.4 7.9 10.9 11.3 12.9 10.0 9.6 12.6 15.2 13.0 10.3 9.0 10.9 7.0 12.6 15.6 9.8 14.8 11.0 9.7 6.5 12.4 9.6 8.8 10.6 11.9 9.3 16.9 13.4 7.5 15.0 13.2 7.3 9.2 13.8 9.0 13.4 13.8 6.1 6.0 12.1 7.3 9.7 15.5 5.2 12.6 13.9 13.5 8.7 7.3 13.5 24.4 9.1 13.3 14.1 11.9 15.7 9.8 10.4 10.8 12.4 9.3 13.9 2.1 16.2 7.7 15.6 6.7 5.8 13.3 16.1 13.1 7.2 9.9 4.7 13.4 2.0 4.0 11.9 5.9 23.2 11.2 12.1 15.2 14.8 7.4 10.2 23.1 4.3 14.2 2.7 5.1 7.0 10.1 23.5 27.7 6.4 12.0 3.4 4.8 12.3 13.6 1.7 7.1 8.3 10.7 5.0 11.9 11.2 7.9 12.7 9.3 9.0 12.2 2.5 20.0 6.7 15.2 2.4 8.2 5.2 9.5 8.7 9.9 9.7 12.3 10.1 15.5 8.9 10.4 13.5 1.0 13.9 12.6 10.4 8.9 8.7 17.1 14.7 12.2 24.9 15.2 13.0 12.6 15.6 12.4 9.0 3.0 3.0 1.4 3.9 2.6 7.6 3.6 0.0 5.3 3.4 1.8 0.0 4.2 11.6 8.3 1.1 3.2 2.2 0.0 6.0 3.1 4.6 2.4 0.0 2.6 8.0 15.9 1.7 8.0 3.2 1.0 3.7 3.6 5.0 13.6 2.8 10.8 5.8 0.0 4.9 4.9 5.3 0.0 3.8 14.0 4.7 2.0 2.9 2.5 3.1 2.0 TGDS "SDR2E1, TDPGD" ENSG00000088451 "TDP-glucose 4,6-dehydratase" O95455 13 94574051-94596257 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039927, HPA040857" Approved Approved Nucleoplasm,Nucleoli,Cytosol Yes No Nucleoplasm "Nucleoli, Cytosol" "HPA039927: AB_10795238, HPA040857: AB_10794867" "unprognostic (4.07e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.27e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (2.87e-1)" "unprognostic (9.99e-2)" "unprognostic (1.96e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (5.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-2)" "unprognostic (1.09e-1)" 11.1 12.2 7.9 11.4 11.8 5.8 13.4 8.0 7.8 11.9 9.0 9.0 13.4 11.1 13.7 13.2 10.3 10.5 8.7 7.7 7.0 7.0 11.8 31.9 7.8 12.5 11.8 6.8 13.9 14.1 6.2 24.3 10.8 10.1 10.5 10.6 15.4 12.5 12.7 7.6 7.9 11.1 10.3 12.6 11.9 9.8 7.2 12.6 27.1 15.8 8.9 12.5 10.9 9.2 9.9 8.0 10.5 7.0 10.4 17.4 6.7 7.4 3.1 5.2 4.7 7.7 6.2 6.5 6.8 6.5 6.4 6.2 8.5 7.3 11.4 6.9 4.7 4.2 4.7 9.2 5.3 6.6 9.0 3.6 9.2 3.6 7.9 9.8 31.4 6.3 7.2 4.2 3.6 10.3 5.1 5.9 8.4 9.0 4.0 5.8 4.5 8.6 16.2 6.9 12.0 4.0 7.3 5.3 6.7 8.1 3.3 7.4 4.1 5.1 10.8 19.0 9.1 4.8 17.1 5.5 2.6 6.8 3.9 5.6 9.1 4.9 42.1 7.0 11.7 7.0 10.5 5.3 9.6 9.6 6.2 14.5 9.9 11.3 10.5 8.0 7.3 17.4 12.4 1.5 10.4 7.0 7.1 12.5 6.7 7.9 11.8 8.0 7.8 7.0 7.0 11.8 6.8 10.1 12.6 11.9 5.0 15.6 9.5 2.2 4.5 4.7 0.0 10.7 10.3 7.0 2.0 12.9 8.3 9.8 1.1 6.3 5.5 0.0 8.0 15.4 12.0 9.9 10.5 19.8 10.0 1.6 5.2 9.2 7.6 0.4 13.3 9.6 8.5 12.6 8.1 6.3 8.2 7.0 7.8 13.3 4.0 25.8 6.4 12.0 10.4 3.1 8.7 8.7 8.0 8.7 TKFC "DAK, DKFZP586B1621, NET45" ENSG00000149476 "Triokinase and FMN cyclase" Q3LXA3 11 61333210-61353295 "Enzymes, Predicted intracellular proteins" "Kinase, Lyase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 90.2;liver: 42.8" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 92.7;Proximal tubular cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 40.5;RPMI-8226: 42.7;T-47d: 42.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039486, HPA048186" Enhanced Approved Nucleoplasm,Cytosol NA NA 4800000 Cytosol Nucleoplasm "HPA039486: AB_10795402, HPA048186: AB_2680305" "unprognostic (4.00e-1)" "unprognostic (3.13e-1)" "unprognostic (7.42e-2)" "prognostic favorable (1.32e-5)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (3.02e-2)" "unprognostic (2.81e-3)" "unprognostic (1.49e-1)" "unprognostic (2.47e-1)" "unprognostic (1.51e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.38e-5)" "unprognostic (2.07e-2)" "unprognostic (8.96e-2)" "unprognostic (3.30e-1)" "unprognostic (4.02e-1)" 3.1 34.7 3.6 6.1 5.3 5.3 4.6 3.7 7.3 3.4 43.4 7.6 8.0 69.5 4.6 7.8 6.2 5.9 8.8 2.8 3.1 2.6 17.4 42.8 3.5 5.2 3.3 5.3 4.5 9.8 3.0 5.5 3.9 4.4 5.0 2.3 7.3 7.2 7.1 4.6 6.1 90.2 2.6 3.1 5.4 5.7 17.1 3.4 5.5 6.4 6.3 6.7 5.4 3.9 9.7 18.4 5.4 11.4 5.3 10.9 7.8 6.1 15.6 2.7 9.5 3.4 3.7 7.7 3.6 3.9 3.4 2.2 7.1 14.8 7.6 12.6 2.6 3.5 8.6 5.1 6.7 1.1 13.1 6.8 4.7 8.2 40.5 5.9 3.9 7.9 5.9 4.6 3.2 11.2 2.9 3.3 5.3 8.2 14.8 2.4 27.9 3.5 3.6 7.5 5.8 10.7 6.2 4.3 42.7 5.4 10.9 10.6 9.5 6.6 11.6 6.0 1.9 42.8 2.8 4.0 6.7 7.0 5.3 2.1 27.4 22.6 6.9 6.9 3.7 6.1 2.3 11.4 5.4 6.7 6.8 8.6 9.7 7.8 6.5 18.4 9.7 5.6 5.9 0.9 5.3 5.3 9.0 10.9 7.8 3.6 5.3 3.7 7.3 3.1 2.6 3.3 5.3 4.4 3.4 0.0 12.6 6.7 10.8 0.0 12.9 3.4 12.7 20.1 12.5 14.0 13.7 25.7 24.9 15.5 7.9 4.5 5.4 0.0 12.8 4.4 3.0 11.6 7.0 92.7 14.9 7.9 12.9 6.2 18.3 9.3 14.1 5.9 0.0 27.9 13.9 8.7 12.3 18.1 21.2 63.4 16.0 6.5 2.4 39.2 14.5 0.0 12.7 5.7 18.4 10.6 TSEN2 "MGC2776, SEN2, SEN2L" ENSG00000154743 "TRNA splicing endonuclease subunit 2" Q8NCE0 3 12484432-12539623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 41.2;Rod photoreceptor cells: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027120, HPA027125, HPA027268" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA Nucleoplasm "Centrosome, Cytosol" "HPA027120: AB_10600197, HPA027125: AB_10601896, HPA027268: AB_10601347" "unprognostic (5.58e-2)" "unprognostic (4.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.71e-2)" "unprognostic (9.59e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (1.42e-1)" "unprognostic (5.66e-2)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "unprognostic (6.15e-2)" "unprognostic (1.41e-2)" "unprognostic (6.99e-2)" "unprognostic (4.90e-2)" "unprognostic (6.06e-2)" "prognostic favorable (3.49e-4)" 8.8 10.6 9.7 8.8 19.1 6.7 10.9 16.5 14.0 10.4 9.8 12.7 8.4 5.8 14.0 9.9 7.9 12.8 10.3 14.3 10.5 12.3 9.8 7.3 7.3 10.9 11.5 7.6 18.0 11.9 14.3 15.3 4.9 10.2 10.5 10.9 13.5 7.2 13.1 16.7 15.3 6.1 12.3 12.3 6.1 8.5 11.3 9.1 9.9 12.5 9.6 8.1 8.6 8.3 8.5 7.1 2.6 4.2 5.0 13.7 5.6 7.8 13.7 7.4 9.6 12.5 13.3 17.0 7.4 6.6 8.0 5.8 7.7 8.4 9.4 5.2 6.0 9.5 7.3 12.3 12.7 9.1 7.4 15.2 10.3 18.3 7.9 9.6 16.2 4.0 11.5 14.8 14.5 17.8 5.9 6.4 13.8 15.3 5.2 9.2 14.8 12.4 7.4 10.4 22.2 16.5 9.4 5.1 18.9 11.9 8.1 4.8 8.4 6.9 6.2 5.8 5.3 11.2 11.3 5.7 5.1 5.0 6.9 11.5 4.9 12.5 11.8 6.8 16.4 6.3 2.4 4.2 0.3 6.4 4.2 10.9 8.5 9.8 7.4 5.9 8.3 13.7 11.7 2.6 5.0 3.6 7.1 3.5 5.6 9.7 19.1 16.5 14.0 10.5 12.3 11.5 7.6 10.2 9.1 3.0 3.5 10.9 9.7 2.6 27.2 6.2 15.3 9.4 2.3 10.4 41.2 7.4 1.7 4.9 1.3 5.6 2.6 0.0 3.7 3.2 3.8 5.0 4.7 5.5 4.1 9.5 4.1 3.1 4.0 2.1 8.3 3.2 3.3 1.0 4.7 8.7 3.5 3.5 9.6 5.0 33.9 6.5 5.1 10.3 19.3 4.3 1.6 5.7 8.2 8.0 TSEN34 "LENG5, SEN34, SEN34L" ENSG00000170892 "TRNA splicing endonuclease subunit 34" Q9BSV6 19 54189938-54194536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Disease mutation, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.8" "Group enriched" "Detected in many" 6 "granulocytes: 24.8;monocytes: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041111, HPA048208" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA041111: AB_10794263, HPA048208: AB_2680313" "unprognostic (3.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (3.48e-2)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.44e-7)" "unprognostic (2.38e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.04e-3)" "unprognostic (8.98e-2)" "unprognostic (4.55e-3)" "unprognostic (2.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.12e-1)" 12.3 28.0 10.4 10.8 10.2 8.2 15.4 4.0 12.8 19.8 19.5 9.4 19.2 3.0 17.3 23.4 20.2 25.3 18.1 20.0 8.8 9.8 15.4 20.0 13.4 18.2 8.7 8.9 31.8 27.3 19.2 14.3 22.0 8.7 23.2 12.3 15.7 17.8 29.5 15.7 14.7 9.8 18.6 7.8 18.0 13.0 27.3 7.7 12.9 28.5 19.6 14.9 19.8 15.5 1.4 2.6 24.8 8.1 0.8 2.4 1.5 29.2 4.3 11.9 17.0 7.1 14.4 13.0 3.6 7.4 8.8 8.3 2.2 4.2 2.2 1.0 5.7 15.3 20.6 16.2 21.5 6.5 7.6 24.6 2.6 0.8 2.4 6.7 0.8 3.6 23.2 9.9 6.0 7.1 7.4 18.1 0.0 5.9 1.4 18.8 3.6 1.5 0.0 2.7 18.6 3.2 7.3 8.1 1.0 25.5 2.5 0.6 6.9 0.8 21.8 8.0 7.7 17.3 2.1 1.2 0.0 12.3 12.8 22.4 8.3 8.0 2.1 21.3 1.3 13.5 4.1 8.1 17.8 0.9 3.3 1.8 1.0 1.3 2.4 2.3 1.4 2.3 0.9 24.8 0.8 5.2 2.6 0.7 1.5 10.4 10.2 4.0 12.8 8.8 9.8 8.7 8.9 8.7 7.7 11.9 20.1 13.7 83.2 65.4 36.0 10.5 50.9 33.5 6.8 41.8 27.5 85.1 81.2 59.2 19.5 32.8 50.1 0.0 52.3 87.0 54.1 67.1 26.5 33.9 49.4 15.9 73.7 33.7 31.5 13.0 62.7 44.3 43.9 23.4 79.0 62.4 50.8 51.8 62.6 85.1 41.1 58.2 56.2 46.1 66.6 61.4 92.8 29.7 61.7 51.5 TYW1 "FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W" ENSG00000198874 "TRNA-yW synthesizing protein 1 homolog" Q9NV66 7 66995173-67239519 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: AB_2668852, HPA014118: AB_2668941, HPA015535: AB_1856487, HPA043136: AB_2678333, HPA047029: AB_2679909, HPA047052: AB_2679918, HPA052097: AB_2681723" "unprognostic (1.53e-1)" "unprognostic (5.49e-3)" "unprognostic (1.62e-1)" "unprognostic (3.05e-2)" "unprognostic (1.84e-2)" "unprognostic (2.20e-1)" "unprognostic (1.83e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.86e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-2)" "unprognostic (4.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.36e-2)" "unprognostic (1.79e-2)" 15.4 19.1 10.2 12.3 15.4 11.9 15.1 14.9 15.3 18.8 12.9 21.2 18.2 14.1 22.7 15.3 12.0 15.5 10.8 12.9 10.8 9.8 15.2 17.7 11.1 15.5 14.1 10.8 19.4 23.9 22.9 28.0 13.2 14.5 14.9 16.5 17.8 15.3 14.7 26.2 14.4 12.8 14.0 13.9 15.1 12.6 13.7 13.4 19.7 19.0 13.6 23.3 15.3 15.2 9.6 8.3 3.6 9.1 11.2 11.8 5.3 10.6 13.6 8.3 17.2 12.5 8.7 9.7 11.4 8.7 9.0 8.5 15.5 13.9 18.5 17.5 10.5 12.7 12.6 17.2 14.0 13.1 14.5 13.2 8.0 11.3 10.5 12.4 18.4 10.6 8.9 14.2 12.2 18.8 7.1 8.2 13.5 21.0 11.2 10.3 10.5 11.6 15.5 14.6 18.0 12.2 13.2 11.6 23.3 12.2 10.8 12.8 12.7 13.7 26.6 11.4 16.6 18.1 13.1 9.6 10.4 7.4 8.2 15.5 11.3 15.9 22.3 8.5 17.4 14.3 2.0 7.0 3.6 8.6 7.8 11.7 8.5 9.4 9.8 8.3 9.6 11.5 11.8 2.0 11.2 9.1 6.6 6.8 5.3 10.2 15.4 14.9 15.3 10.8 9.8 14.1 10.8 14.5 13.4 6.0 15.4 4.5 4.9 9.3 9.0 8.1 10.2 9.4 4.5 10.4 3.9 16.5 0.0 6.6 5.5 6.7 4.7 0.0 6.0 10.7 7.7 4.9 33.5 12.5 6.9 3.2 4.6 6.7 4.3 3.1 7.8 8.9 8.5 10.0 12.1 7.7 6.1 3.5 7.8 2.1 11.7 19.4 7.1 17.0 22.7 14.8 12.7 8.5 9.7 2.8 UMPS ENSG00000114491 "Uridine monophosphate synthetase" P11172 3 124730366-124749273 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Syncytiotrophoblasts: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036178, HPA036179" Uncertain Approved Cytosol NA NA Cytosol "HPA036178: AB_10673002, HPA036179: AB_10673615" "unprognostic (6.41e-2)" "unprognostic (6.70e-2)" "unprognostic (1.79e-2)" "unprognostic (1.13e-3)" "unprognostic (2.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.15e-3)" "unprognostic (5.51e-2)" "unprognostic (4.85e-3)" "unprognostic (1.43e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.18e-2)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 8.4 12.2 4.9 6.8 6.8 4.8 8.0 9.3 7.6 5.9 9.1 8.5 5.2 8.4 6.8 6.7 13.2 8.2 6.6 3.6 4.0 3.9 9.6 20.7 5.2 10.1 7.3 3.6 8.9 19.0 9.5 9.3 11.6 4.7 6.4 7.1 6.4 8.9 4.0 10.9 9.5 8.5 5.5 5.9 9.8 8.3 6.8 6.2 10.6 7.4 12.0 9.3 7.8 6.4 16.6 13.1 4.6 9.8 10.2 13.0 7.9 1.4 4.4 5.0 2.1 3.0 3.5 5.3 7.5 2.3 3.2 2.7 3.8 2.0 3.8 8.3 2.9 6.6 8.4 7.1 2.5 5.0 4.4 4.1 7.8 2.8 2.6 2.6 8.2 5.9 3.9 2.3 2.0 3.9 1.9 1.4 7.7 3.5 1.8 2.3 3.4 10.0 1.6 11.1 3.9 2.8 6.6 6.0 3.2 2.5 2.5 4.0 2.6 11.3 4.0 4.2 3.8 4.0 3.0 14.4 2.5 5.0 6.9 3.0 7.5 10.2 10.5 2.8 3.4 2.5 4.5 9.0 4.6 12.5 9.8 12.1 13.7 8.9 11.3 13.1 16.6 13.0 10.4 0.6 10.2 8.0 9.7 10.3 7.9 4.9 6.8 9.3 5.7 4.0 3.9 7.3 3.6 4.7 6.2 6.0 7.8 5.2 15.9 14.1 8.0 5.7 12.7 22.7 10.3 8.7 3.9 56.7 24.9 23.5 3.1 13.4 10.4 0.0 26.6 27.5 9.3 9.3 11.5 28.8 19.3 4.8 9.2 8.0 5.4 3.9 12.7 9.6 3.3 21.6 9.4 10.1 19.5 7.0 13.1 19.5 7.7 12.9 9.9 19.7 30.7 16.7 91.3 12.8 15.8 15.5 URAD PRHOXNB ENSG00000183463 "Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase" A6NGE7 13 27977714-27988654 "Enzymes, Predicted intracellular proteins" "Purine metabolism" "Decarboxylase, Lyase" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "breast: 8.8;intestine: 16.7" "Group enriched" "Detected in some" 5 "Enterocytes: 112.1;Mucus-secreting cells: 56.3;Paneth cells: 57.5" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BEWO: 6.9;CACO-2: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA038972 Uncertain NA NA "HPA038972: AB_10671869" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (5.21e-2)" 2.8 0.0 0.1 1.5 0.1 0.0 8.8 0.6 0.1 0.1 16.7 0.1 0.1 8.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 16.0 0.2 0.1 0.1 0.0 0.2 0.1 0.6 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 0.0 112.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 56.3 0.0 0.0 57.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 UROC1 "FLJ31300, HMFN0320" ENSG00000159650 "Urocanate hydratase 1" Q96N76 3 126481281-126517773 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "liver: 50.7" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 31.8" "Cancer enriched" "Detected in single" 100 "liver cancer: 12.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enhanced" "Detected in single" "granulocytes: 1.5" "Cell line enriched" "Detected in some" 8 "NB-4: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069863 Enhanced NA NA 510000 "HPA069863: AB_2732143" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-2)" "unprognostic (6.43e-2)" "unprognostic (1.43e-1)" "unprognostic (2.23e-3)" "unprognostic (2.95e-1)" "unprognostic (2.57e-2)" "unprognostic (7.71e-2)" "unprognostic (9.97e-2)" "unprognostic (3.04e-1)" "unprognostic (3.65e-5)" "unprognostic (3.97e-2)" "unprognostic (2.66e-1)" "unprognostic (5.52e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 9.5 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 31.8 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UROD ENSG00000126088 "Uroporphyrinogen decarboxylase" P06132 1 45012147-45015575 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Decarboxylase, Lyase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 11 "Erythroid cells: 607.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027468, HPA028668, HPA030350" Uncertain Supported Nucleoplasm,Cytosol NA NA 5200000 "Nucleoplasm, Cytosol" "HPA027468: AB_1858654, HPA028668: AB_10603458, HPA030350: AB_2673440" "unprognostic (5.90e-2)" "unprognostic (2.94e-2)" "unprognostic (2.49e-1)" "unprognostic (9.61e-2)" "unprognostic (7.94e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.48e-4)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (6.75e-2)" "unprognostic (7.72e-3)" "unprognostic (3.92e-1)" "unprognostic (1.24e-1)" "unprognostic (4.68e-2)" "unprognostic (1.41e-1)" "unprognostic (8.73e-2)" "unprognostic (8.12e-2)" 20.7 50.2 23.1 12.2 26.2 67.5 20.7 14.2 28.6 17.7 24.2 16.5 25.9 11.2 27.8 22.6 17.8 20.8 17.4 34.0 21.1 20.3 29.6 58.1 14.3 14.8 21.6 22.9 27.4 18.4 35.9 17.6 25.8 16.2 19.2 12.3 24.3 45.6 19.2 28.8 12.1 13.2 22.9 18.9 16.6 15.0 16.3 11.5 17.2 26.3 23.6 16.0 15.0 13.0 25.7 48.6 20.6 36.3 26.0 27.4 35.6 12.7 8.4 13.4 17.7 23.3 21.9 6.5 15.6 40.4 33.0 25.4 12.1 6.8 9.1 16.6 23.7 23.3 6.6 25.6 30.5 23.0 8.1 26.9 47.0 19.4 39.9 27.1 14.3 8.7 22.7 19.4 31.4 25.5 24.4 42.3 17.6 81.5 10.0 31.4 10.7 9.7 12.4 20.9 10.2 29.7 14.7 20.0 13.1 28.7 10.9 14.4 11.3 17.1 12.9 26.4 15.9 10.1 15.0 27.3 18.8 14.7 6.5 25.2 10.4 11.1 7.6 29.4 21.7 9.4 17.6 36.3 20.6 19.7 25.8 20.0 25.7 23.8 19.2 48.6 23.7 22.3 20.3 6.6 26.0 15.5 32.4 27.4 35.6 23.1 26.2 14.2 28.6 21.1 20.3 21.6 22.9 16.2 11.5 41.7 38.9 45.2 26.1 20.4 23.6 60.9 40.8 22.7 18.2 26.2 15.7 83.3 76.3 62.1 7.2 47.7 22.7 607.3 55.7 45.2 63.6 19.5 50.8 86.0 88.6 12.7 17.2 30.7 34.3 12.5 73.6 37.9 45.5 163.3 18.4 80.8 47.4 21.8 52.6 99.3 21.8 38.8 41.5 35.1 38.5 21.7 41.6 21.8 17.4 22.2 UROS ENSG00000188690 "Uroporphyrinogen III synthase" P10746 10 125784980-125823248 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Erythroid cells: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044038 Approved Approved Nucleoplasm,Cytosol NA NA 15000 Nucleoplasm Cytosol "HPA044038: AB_10966692" "unprognostic (8.86e-2)" "unprognostic (7.64e-2)" "unprognostic (2.77e-1)" "unprognostic (7.19e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (5.82e-2)" "unprognostic (1.27e-1)" "unprognostic (4.35e-3)" "unprognostic (4.23e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (3.93e-1)" 13.8 16.1 48.6 9.0 46.6 33.2 13.9 12.8 35.3 8.9 11.4 15.7 12.8 13.2 9.3 41.2 10.5 11.3 11.5 31.4 36.9 20.4 22.6 25.5 10.0 16.8 22.7 23.4 14.5 14.1 14.4 12.0 7.9 20.0 12.9 12.4 14.0 18.1 14.0 45.6 9.8 12.0 13.0 12.5 11.7 12.5 13.8 13.8 10.8 16.4 14.4 12.7 9.4 6.3 17.3 27.1 2.4 15.6 24.7 21.3 17.8 17.7 19.3 14.1 31.2 18.8 19.1 19.0 23.0 39.8 16.2 16.2 8.3 21.6 24.8 10.7 28.5 11.3 10.2 8.1 16.3 15.2 30.6 15.5 52.7 10.9 13.7 26.6 22.2 12.4 23.9 9.4 11.3 30.3 22.5 14.8 18.4 9.1 23.6 27.0 21.2 19.4 25.0 15.3 13.3 20.1 13.8 15.5 14.7 21.2 11.0 11.0 19.0 23.0 17.8 31.2 15.0 15.8 21.2 14.7 21.5 8.0 16.5 19.5 21.8 15.8 16.9 29.9 9.0 10.1 2.4 15.6 2.2 16.1 15.4 18.5 15.7 16.0 20.4 27.1 17.3 21.3 16.3 1.2 24.7 14.6 12.9 14.2 17.8 48.6 46.6 12.8 35.3 36.9 20.4 22.7 23.4 20.0 13.8 17.9 20.2 41.0 10.4 8.2 45.4 60.5 33.1 20.1 17.0 34.9 43.2 49.6 86.2 49.2 45.5 19.3 27.7 186.9 52.4 38.4 25.6 22.0 11.5 53.9 68.9 44.5 13.9 27.6 41.0 95.8 33.1 23.1 59.1 66.7 19.6 51.6 42.5 10.5 38.2 117.1 33.3 6.5 28.2 41.5 71.3 11.2 16.7 38.9 37.7 19.7 UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093303-106194339 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" NA NA 10000 "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.45e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" 12.3 11.7 15.2 17.3 19.9 20.7 20.1 23.0 20.5 14.1 13.3 11.9 27.6 9.5 16.1 22.3 15.6 19.2 16.2 20.0 17.0 18.2 40.2 16.1 28.8 20.7 15.1 11.6 16.3 17.0 18.6 13.4 37.9 19.6 16.2 15.6 14.7 11.6 17.6 18.0 11.5 9.9 13.8 22.9 19.7 17.9 19.4 10.6 15.0 26.2 14.1 19.1 21.6 15.3 11.6 7.5 11.2 9.8 11.9 34.1 15.1 16.5 12.5 13.2 10.0 23.6 17.6 28.6 18.3 17.2 13.0 16.2 24.5 28.3 3.0 22.8 18.9 29.2 8.4 5.7 15.0 14.2 15.9 10.0 9.1 5.6 27.5 9.3 7.4 10.1 11.4 16.6 13.2 8.9 15.1 13.6 5.8 5.3 7.3 26.8 11.8 8.2 15.9 15.5 16.0 16.8 15.3 10.0 8.5 83.9 15.6 4.4 4.9 13.1 11.8 10.8 18.6 4.4 23.6 12.2 14.6 15.3 11.8 11.3 9.0 12.4 4.1 14.5 16.6 26.7 3.9 9.8 11.2 8.8 8.0 9.5 4.9 19.6 14.3 7.5 11.6 25.4 17.6 2.0 11.9 5.3 5.4 34.1 15.1 15.2 19.9 23.0 20.5 17.0 18.2 15.1 11.6 19.6 10.6 83.4 72.6 12.3 22.3 14.9 9.1 15.3 22.9 29.4 61.4 82.0 3.9 59.1 43.1 42.5 42.6 18.9 11.0 23.3 21.9 60.0 31.9 15.7 28.9 12.9 29.5 7.9 6.3 8.6 19.8 11.4 14.1 25.4 13.5 80.2 14.3 10.0 25.7 10.5 12.0 16.7 6.8 19.4 20.8 11.9 59.8 11.5 20.6 30.5 19.9 15.5