Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065379-125143333 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA Vesicles "HPA058815: AB_2683826" "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" 21.1 6.5 9.0 10.5 13.0 2.5 33.7 6.6 22.0 11.7 9.3 5.3 7.4 12.9 5.2 7.7 22.3 6.6 12.9 5.8 8.1 5.6 6.8 3.3 4.9 4.9 5.1 13.1 4.9 9.7 5.8 6.7 4.8 10.0 6.7 8.6 5.1 33.7 12.9 3.7 26.9 8.7 4.5 4.2 4.3 12.7 9.7 3.6 6.8 7.6 12.2 8.7 5.0 9.9 3.0 11.8 6.9 2.3 5.8 5.7 3.8 14.5 14.5 6.3 8.6 23.4 15.3 10.6 11.8 11.3 14.0 12.6 18.7 9.7 9.0 12.2 14.2 6.1 15.9 11.8 12.7 7.6 9.7 10.8 7.2 9.7 14.2 19.5 5.1 7.3 16.9 10.4 11.9 12.1 17.6 10.2 5.3 5.0 5.6 8.9 26.6 5.9 6.8 8.0 15.3 17.2 1.1 16.1 12.4 14.3 22.2 17.0 4.9 12.5 19.8 9.1 6.5 14.8 11.3 9.7 6.8 10.8 7.6 9.0 12.7 7.2 9.8 8.5 8.4 7.4 6.9 2.3 6.7 4.2 0.7 5.4 3.0 3.9 3.2 2.8 1.7 5.7 3.8 0.3 5.8 0.8 11.8 2.4 3.8 9.0 13.0 6.6 22.0 8.1 5.6 5.1 13.1 10.0 3.6 6.0 12.9 0.8 4.9 14.7 16.4 7.3 12.7 0.0 5.7 5.2 25.5 1.8 6.6 9.5 54.0 5.8 9.9 0.0 9.5 7.4 11.4 9.4 2.3 2.5 4.1 6.4 24.2 0.6 3.2 14.6 8.6 2.8 5.0 5.4 20.1 5.4 8.7 5.8 4.9 6.2 20.1 0.0 7.6 12.7 5.4 24.6 2.1 9.2 15.1 4.9 AARS "AlaRS, CMT2N" ENSG00000090861 "Alanyl-tRNA synthetase" P49588 16 70252295-70289543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034261, HPA040870" Supported Supported Cytosol NA NA 700000 Cytosol "CAB034261: AB_1562673, HPA040870: AB_10794995" "unprognostic (1.98e-2)" "unprognostic (6.87e-2)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (3.58e-1)" "unprognostic (2.50e-2)" "unprognostic (7.99e-2)" "unprognostic (2.36e-1)" "unprognostic (1.99e-1)" "unprognostic (1.76e-1)" "unprognostic (8.33e-2)" "unprognostic (2.92e-1)" "unprognostic (3.42e-2)" "unprognostic (3.75e-2)" "unprognostic (2.05e-3)" "unprognostic (8.22e-2)" "unprognostic (3.83e-3)" 22.8 25.3 28.0 19.6 34.8 5.9 22.6 36.4 54.0 22.3 18.4 30.6 21.4 16.8 22.0 33.9 14.5 20.4 14.1 20.9 29.5 31.7 25.5 36.4 19.5 17.9 40.3 40.5 18.7 45.4 61.2 23.1 21.0 37.5 23.2 17.5 17.3 30.1 30.0 25.2 14.1 14.4 28.4 33.2 16.7 21.1 12.2 32.7 10.3 42.1 10.6 20.9 17.7 26.9 13.4 11.6 3.9 13.3 21.3 13.4 11.6 23.3 39.3 10.8 40.3 25.4 23.1 26.2 18.5 25.7 23.4 29.6 32.2 31.5 26.5 24.9 18.6 17.9 27.3 31.3 25.2 32.9 12.0 11.3 26.1 16.7 28.5 67.3 15.6 15.7 27.3 38.1 44.9 100.6 18.6 23.1 41.9 33.2 35.0 17.4 52.8 16.8 18.3 20.4 30.1 22.7 32.1 6.9 57.9 15.9 12.0 13.5 11.6 51.4 12.1 45.5 16.1 37.9 34.5 15.3 17.3 16.8 17.1 15.4 49.4 32.4 48.9 29.5 24.5 33.8 3.9 8.6 3.9 12.6 12.7 12.8 13.4 10.9 12.1 11.6 11.4 13.1 13.4 1.3 21.3 13.3 7.9 8.4 11.6 28.0 34.8 36.4 54.0 29.5 31.7 40.3 40.5 37.5 32.7 8.9 17.3 8.2 15.7 7.3 35.7 22.2 17.8 14.7 11.4 8.7 17.7 53.2 29.9 24.7 8.6 14.3 9.8 46.7 25.3 24.1 12.2 18.2 20.7 43.2 23.5 52.4 22.4 19.0 9.4 5.2 29.1 9.8 11.8 34.3 13.3 35.9 23.6 8.6 38.2 27.4 38.4 0.0 13.9 17.5 29.0 7.4 43.5 10.5 12.1 13.3 AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44299654-44313326 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease mutation, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA Mitochondria "HPA035636: AB_10670837, HPA061396: AB_2684502" "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" 8.6 10.7 15.9 16.2 11.8 11.4 9.9 23.5 19.8 11.4 14.5 11.4 13.0 15.3 14.1 10.4 17.2 13.4 15.9 10.4 13.2 8.9 10.3 12.6 10.9 13.4 12.4 14.3 17.1 13.8 16.2 14.2 10.1 11.1 13.2 9.8 11.2 14.4 14.6 10.2 16.8 18.3 12.1 8.8 14.1 12.3 12.9 14.1 14.7 12.3 10.4 13.4 10.2 13.9 7.1 3.2 3.7 3.4 3.7 5.5 2.8 9.7 7.3 9.6 17.6 5.7 5.2 12.7 8.0 4.1 8.5 8.2 7.9 5.3 10.7 12.8 3.5 9.0 7.3 10.6 11.5 3.3 7.5 16.9 12.4 7.1 9.3 3.7 11.5 11.1 4.4 7.3 6.8 7.3 5.2 7.2 15.0 14.6 10.5 4.5 10.9 9.6 9.9 7.1 28.1 7.1 11.5 5.8 7.3 4.4 8.8 22.8 8.2 6.9 7.8 10.7 6.7 7.2 15.0 6.1 9.2 9.3 5.7 10.0 6.2 5.7 11.0 5.2 10.2 15.9 3.7 2.4 0.0 3.4 3.3 5.5 3.6 4.8 4.4 2.6 7.1 4.7 4.3 0.7 3.7 3.4 3.2 3.0 2.8 15.9 11.8 23.5 19.8 13.2 8.9 12.4 14.3 11.1 14.1 6.0 3.5 2.4 1.9 0.6 6.3 2.8 7.6 4.0 3.4 0.0 11.8 4.4 0.0 2.1 2.2 2.9 4.4 0.0 0.3 4.4 1.4 1.2 0.0 2.4 2.7 0.0 0.0 3.7 2.8 0.4 4.4 1.6 0.0 5.4 1.4 1.5 1.1 0.0 4.2 0.8 6.7 0.0 1.4 3.3 7.0 0.4 4.5 2.2 3.3 1.4 ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084988-37406818 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 10.7 4.8 5.6 2.5 7.7 3.0 18.5 6.0 11.5 5.3 4.2 6.9 12.7 3.8 4.5 11.7 9.2 3.8 3.6 2.3 4.9 3.0 5.8 7.3 3.5 6.3 4.6 4.3 2.3 13.6 7.9 2.6 6.1 12.2 5.1 4.8 4.6 14.4 11.3 5.4 2.5 7.8 4.2 2.3 3.9 5.5 5.7 2.0 4.2 4.5 5.0 4.3 4.6 4.4 3.2 1.3 4.1 2.0 3.9 2.0 14.9 3.1 18.2 19.1 25.4 25.1 6.3 6.6 9.4 6.9 12.6 12.1 2.6 2.0 5.4 10.7 18.3 15.4 3.3 22.6 10.9 5.9 9.9 11.9 7.9 12.3 4.0 6.4 2.4 20.2 13.2 18.4 13.7 8.7 12.2 10.7 28.3 1.4 1.0 12.6 6.8 9.8 13.8 9.4 9.9 10.5 11.4 2.7 16.4 16.9 20.6 8.1 11.9 5.6 5.3 16.5 11.2 7.4 10.8 5.9 9.4 8.2 1.6 4.0 4.7 18.6 5.4 5.4 8.1 1.1 2.8 0.3 2.3 4.1 2.1 2.7 2.5 2.7 3.2 4.4 3.9 2.7 1.3 2.0 2.7 2.4 3.2 2.0 29.8 40.1 3.7 15.6 10.3 15.4 6.5 2.5 8.1 12.5 10.4 25.5 14.2 8.3 5.9 46.0 7.5 4.8 23.3 7.2 5.4 7.5 20.3 6.9 8.1 5.0 22.3 8.6 4.3 2.1 39.8 9.2 4.2 10.1 3.6 7.2 19.9 6.5 5.8 14.9 5.0 10.7 6.5 4.8 7.9 17.9 13.9 13.6 4.3 8.7 18.2 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "adipose tissue: 104.5;breast: 67.4;liver: 42.0;skeletal muscle: 154.2" "Cell type enhanced" "Detected in many" 14 "Hepatocytes: 159.9;Peritubular cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 15.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.5" "Cell line enriched" "Detected in many" 18 "ASC diff: 73.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA006554 Enhanced "Intracellular and membrane" NA NA "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 104.5 8.2 4.3 10.6 4.0 1.6 67.4 3.3 3.5 3.5 19.3 3.2 6.2 3.8 4.6 4.3 4.9 3.9 10.5 12.1 4.5 2.0 5.4 42.0 3.1 4.0 6.4 2.7 6.8 8.5 8.9 7.1 1.3 3.7 3.6 3.9 4.0 5.8 9.0 154.2 2.8 4.8 7.5 6.5 2.5 5.6 1.6 4.9 0.4 6.2 12.5 1.7 7.3 6.3 2.5 0.2 15.5 0.4 0.1 1.7 0.1 0.2 1.8 1.1 2.2 73.2 0.5 0.8 0.3 0.4 0.3 0.2 1.2 0.3 0.9 0.5 0.3 0.8 1.5 0.9 0.5 0.2 1.1 1.7 2.0 1.8 1.3 0.3 1.7 0.5 0.8 0.4 0.7 0.2 0.5 0.1 1.5 0.2 0.1 0.2 0.5 1.2 1.6 1.2 0.1 3.9 0.6 1.5 0.4 0.6 0.6 0.7 1.7 1.8 0.9 1.1 0.5 0.8 1.8 0.1 0.7 0.4 0.8 0.6 2.8 1.5 1.2 1.7 1.4 0.5 4.1 0.4 15.5 1.1 0.1 0.6 1.7 1.0 0.3 0.2 2.5 1.7 0.9 0.6 0.1 0.2 0.2 0.6 0.1 4.3 4.0 3.3 3.5 4.5 2.0 6.4 2.7 3.7 4.9 6.0 0.6 0.0 2.5 2.1 1.3 29.0 28.1 1.4 2.3 22.7 0.0 0.4 1.7 1.0 27.5 7.1 12.9 0.0 3.6 0.4 5.4 1.4 1.1 159.9 1.6 22.3 9.8 31.3 8.6 31.3 27.0 2.2 5.0 1.0 8.8 7.5 3.5 7.0 47.4 6.5 4.7 6.5 7.6 2.7 2.5 1.4 0.1 0.0 9.7 0.7 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 11.4;brain: 40.5;skin 1: 19.9" "Cell type enhanced" "Detected in some" 22 "Ciliated cells: 26.8;Spermatogonia: 7.7" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NTERA-2: 8.1;SK-MEL-30: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 1.1 11.4 16.9 1.5 26.9 4.5 3.8 6.6 27.0 1.1 1.2 10.5 0.0 1.6 1.2 2.3 1.3 5.9 1.3 1.1 16.4 8.5 1.0 1.0 1.7 1.6 21.1 13.9 1.2 1.0 0.9 0.3 1.1 32.9 2.0 1.1 0.0 1.5 1.4 1.2 19.9 1.5 1.2 40.5 1.3 1.2 5.4 19.0 0.0 1.2 0.0 1.1 1.5 0.2 0.4 3.9 1.2 0.2 0.6 0.2 1.5 0.8 0.1 1.6 2.4 0.0 0.0 0.6 0.5 0.0 0.5 0.1 0.5 0.6 0.8 0.2 0.1 0.6 0.9 0.1 0.3 0.2 0.4 1.4 0.7 1.4 0.7 0.0 0.7 1.6 0.6 0.0 0.4 0.2 0.5 0.2 1.0 0.5 1.1 0.1 0.4 0.6 1.4 8.1 0.7 0.3 0.3 1.0 0.5 0.0 1.0 0.6 0.9 0.4 1.0 3.8 1.0 0.5 0.5 1.0 0.6 0.6 0.5 0.3 0.9 0.3 0.9 0.3 0.6 1.6 0.4 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.4 0.2 0.1 1.2 0.6 0.2 3.9 0.0 1.5 16.9 26.9 6.6 17.9 16.4 8.5 21.1 13.9 32.9 19.0 0.0 1.3 0.0 0.3 1.0 2.1 2.0 0.0 26.8 4.5 0.0 3.9 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.3 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.9 0.0 0.9 0.9 7.7 0.5 0.3 0.0 0.0 0.3 ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "testis: 71.3" "Group enriched" "Detected in some" 68 "Early spermatids: 443.1;Late spermatids: 1482.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;HEL: 3.4;Karpas-707: 2.6;MCF7: 1.0" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA Cytosol "HPA043421: AB_10794182, HPA051013: AB_2681311" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-4)" "unprognostic (1.96e-2)" "unprognostic (4.17e-2)" "unprognostic (2.07e-1)" "unprognostic (2.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.13e-2)" "unprognostic (3.91e-3)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (4.70e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.4 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 2.6 0.0 1.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.5 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1482.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 1.0 0.0 6.5 0.0 14.2 5.7 0.0 1.1 0.0 0.0 0.0 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.0;liver: 190.9" "Group enriched" "Detected in many" 4 "Early spermatids: 359.4;Hepatocytes: 1018.8;Late spermatids: 335.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "neutrophil: 80.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 80.2" "Cell line enhanced" "Detected in many" "ASC diff: 151.2;ASC TERT1: 36.7;HSkMC: 80.3;RPTEC TERT1: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011964" Enhanced Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA Nucleoplasm "Mitochondria, Cytosol" "HPA011316: AB_1844536, HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 105.0 6.7 4.2 14.1 13.5 46.0 54.4 3.2 9.6 7.2 12.2 16.4 5.5 4.9 5.7 12.7 8.8 6.4 5.7 24.3 6.4 4.1 32.8 190.9 20.7 18.9 24.0 3.8 4.2 7.3 5.9 8.7 4.4 11.6 14.2 2.6 9.1 17.9 4.8 89.1 20.4 4.5 6.4 18.2 16.9 6.5 6.4 15.9 2.1 8.3 10.1 5.8 7.6 11.0 0.5 2.2 80.2 8.9 0.7 0.7 2.9 6.1 1.9 1.2 3.1 151.2 36.7 1.0 3.4 1.7 2.0 1.4 0.4 1.7 2.5 0.3 4.0 4.9 3.8 5.4 2.2 1.7 12.4 1.9 1.8 1.7 5.0 24.3 4.9 4.6 80.3 18.6 1.7 8.7 3.6 2.6 0.4 0.8 7.8 9.8 3.2 0.3 6.8 0.2 4.1 2.7 0.9 1.0 3.2 47.8 17.5 4.6 4.3 3.1 9.4 10.5 0.5 3.4 5.0 2.8 1.8 2.1 4.3 1.0 3.0 1.5 1.1 5.8 6.9 2.8 2.3 8.9 2.8 0.5 5.2 0.5 0.5 0.4 0.2 2.2 0.5 0.4 0.3 80.2 0.7 3.6 0.4 0.7 2.9 4.2 13.5 3.2 9.6 6.4 4.1 24.0 3.8 11.6 15.9 23.8 107.2 14.5 16.5 18.7 5.8 89.7 28.1 13.4 21.6 29.6 17.7 8.6 79.6 3.9 359.4 5.6 2.6 0.0 11.0 1.9 9.1 56.1 23.1 1018.8 39.4 3.2 0.0 19.0 136.2 335.5 17.8 64.1 30.4 24.4 4.2 3.3 9.0 0.9 15.6 75.0 10.3 12.9 12.0 8.1 16.7 35.9 2.9 10.0 1.7 21.4 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860934-222944639 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 206.1" "Cell type enhanced" "Detected in all" 9 "Horizontal cells: 494.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 94.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 14.7 17.0 22.8 9.9 26.0 16.3 51.5 19.4 45.9 15.3 16.5 16.1 11.6 12.7 10.9 18.4 28.3 9.0 11.8 22.7 20.9 22.8 17.9 22.3 15.6 10.5 19.6 21.2 11.7 10.3 206.1 8.8 19.1 24.4 44.4 16.7 14.4 34.2 15.5 19.1 11.4 12.7 12.2 22.2 9.7 28.3 13.7 14.2 13.5 17.3 11.2 8.7 14.6 15.4 15.0 22.5 21.8 16.8 16.6 20.1 16.5 10.1 17.9 27.4 29.8 12.0 29.8 7.6 12.9 33.6 15.5 32.7 16.1 26.1 4.8 7.5 12.3 33.5 29.9 5.9 28.7 20.1 8.7 11.2 11.4 14.5 17.9 26.5 7.5 5.6 15.3 40.8 25.6 44.7 11.9 16.8 8.5 21.5 18.6 21.8 21.5 14.6 8.8 13.9 23.0 9.3 8.0 23.2 8.2 22.3 41.6 14.5 10.7 7.6 20.6 94.2 22.1 10.3 18.4 11.6 10.4 16.6 8.9 9.4 6.6 3.2 16.8 11.1 7.1 31.4 16.6 14.6 21.8 20.1 16.8 19.3 11.6 12.8 14.6 15.7 15.0 18.7 16.7 21.8 16.6 15.9 22.5 9.5 16.5 22.8 26.0 19.4 45.9 20.9 22.8 19.6 21.2 24.4 14.2 32.8 58.5 16.4 65.8 41.3 91.7 51.2 40.8 37.5 44.3 34.9 72.6 32.9 6.6 28.6 31.0 38.3 33.1 23.3 27.3 8.4 36.3 113.5 26.5 47.9 33.5 494.2 20.1 36.2 50.2 18.9 24.2 42.9 45.5 32.5 32.3 205.8 32.5 38.6 33.6 12.5 51.8 45.3 51.8 50.2 49.9 42.7 50.7 27.7 46.5 102.1 ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease mutation, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Alveolar cells type 2: 210.9;granulocytes: 598.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 81.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 100000 "Golgi apparatus" Mitochondria "HPA000286: AB_2665966, HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favorable (5.73e-4)" 29.5 31.1 16.3 25.5 18.0 9.2 30.0 13.9 22.8 34.7 10.5 8.8 4.6 10.0 13.7 11.7 11.2 10.7 20.1 20.3 27.6 20.3 31.2 9.6 27.8 29.6 15.2 19.0 13.1 8.8 16.7 12.9 33.9 21.1 9.7 9.7 8.0 10.7 11.0 42.5 9.1 9.0 15.8 24.6 17.0 12.9 17.7 9.7 9.5 12.8 8.5 11.9 19.5 21.0 2.2 6.5 20.3 10.9 2.2 4.0 3.8 13.9 4.5 5.6 6.0 21.1 13.2 4.4 20.5 22.7 20.0 20.9 4.4 9.7 10.0 8.0 14.8 24.6 4.0 4.8 19.7 31.6 3.5 5.0 39.4 6.4 46.6 9.7 9.3 81.7 11.4 7.7 22.8 16.7 11.6 15.0 6.4 1.1 12.3 22.9 0.9 8.1 12.3 7.0 3.1 8.2 5.9 10.3 8.2 28.7 4.5 3.7 2.8 24.5 0.0 12.6 11.5 0.3 10.0 27.7 18.3 5.2 28.9 18.8 6.1 7.0 9.4 32.3 20.9 11.6 15.5 7.0 20.3 2.8 9.8 2.0 2.2 2.5 2.2 6.5 2.2 2.0 2.4 19.8 2.2 10.9 2.6 4.0 3.8 16.3 18.0 13.9 22.6 27.6 20.3 15.2 19.0 21.1 9.7 71.5 210.9 20.6 16.2 19.8 34.7 32.3 10.2 17.4 64.8 69.8 2.0 5.7 43.1 24.1 1.2 28.6 0.7 23.3 22.2 29.6 17.9 10.6 598.2 1.7 22.2 6.4 7.5 17.8 68.3 2.0 5.2 45.1 15.1 64.9 2.9 11.7 26.4 1.4 9.6 10.0 14.5 0.0 22.3 3.9 3.8 7.0 26.4 13.8 1.7 12.4 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 278.7" "Cell type enhanced" "Detected in many" 12 "Enterocytes: 266.6;Paneth cells: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 43.3;RT4: 44.2;U-937: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA 22000 Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 10.0 1.4 3.1 12.7 3.5 2.2 6.4 1.2 3.1 9.3 84.6 1.6 3.8 64.5 8.7 41.8 4.2 8.0 11.2 3.1 3.3 3.1 3.2 56.5 10.8 7.1 4.0 1.2 5.0 1.6 0.1 1.2 2.1 3.9 7.0 21.5 8.4 2.4 4.0 2.6 1.3 278.7 2.6 3.8 12.4 7.7 2.3 2.5 6.3 3.1 2.7 7.2 17.4 6.7 10.8 19.4 16.3 17.0 16.2 25.1 11.7 11.6 0.3 0.2 0.0 0.8 0.1 1.0 0.3 2.3 0.0 0.2 10.6 43.3 14.2 2.6 0.6 2.1 0.1 0.0 0.0 0.2 11.9 0.0 11.1 0.4 18.5 2.8 17.2 18.8 1.9 0.0 0.2 0.0 0.8 0.8 0.0 0.0 6.5 0.0 0.0 0.0 7.9 0.0 9.8 0.4 3.9 0.0 8.7 1.2 44.2 0.0 0.3 17.3 6.6 0.0 0.0 0.0 9.7 12.5 0.1 0.1 0.7 0.7 4.7 0.0 6.9 0.4 21.6 0.0 14.5 9.3 16.3 16.7 17.0 16.6 10.8 13.7 18.4 19.4 8.2 9.5 14.5 2.5 16.2 15.9 6.2 25.1 11.7 3.1 3.5 1.2 3.1 3.3 3.1 4.0 1.2 3.9 2.5 11.9 43.5 21.6 7.4 3.4 0.0 1.4 12.7 5.3 33.0 0.0 3.9 1.6 0.0 12.0 65.8 24.5 266.6 0.0 5.6 1.9 1.7 5.7 17.3 79.9 16.7 0.0 39.2 16.0 19.2 29.7 14.7 23.5 3.3 4.6 84.3 0.0 29.0 93.1 11.3 0.0 1.2 0.0 1.4 1.7 1.4 1.5 0.6 14.9 90.6 41.4 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0;ductus deferens: 30.1;seminal vesicle: 35.8;testis: 23.0" "Cell type enhanced" "Detected in many" 14 "Cone photoreceptor cells: 216.0;Erythroid cells: 116.8;Rod photoreceptor cells: 126.2" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "SCLC-21H: 14.9;U-937: 8.7" HPA040470 Enhanced NA NA "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.6 4.8 16.5 1.5 15.7 21.3 0.7 22.8 34.0 0.5 0.7 5.3 30.1 5.4 0.5 1.0 0.9 0.7 0.9 2.0 12.4 9.7 2.3 2.6 0.8 2.5 9.6 12.1 0.5 1.9 13.0 2.7 1.1 12.1 0.8 0.8 3.3 0.8 35.8 3.6 0.6 3.3 0.5 4.2 1.2 1.2 23.0 4.7 0.0 0.9 0.0 1.5 0.7 0.3 0.1 0.0 0.6 0.1 1.2 4.2 1.1 0.0 0.0 0.3 0.1 0.6 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.5 0.1 1.6 0.2 0.0 0.0 0.9 0.1 0.0 2.2 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.0 2.1 1.0 0.2 0.0 0.0 0.0 1.5 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 14.9 0.7 0.2 0.2 1.2 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.5 0.0 0.3 8.7 0.5 0.6 0.1 0.1 1.5 0.0 3.5 0.1 2.1 4.2 0.0 0.1 3.9 1.8 0.2 1.2 0.0 0.0 0.1 1.1 16.5 15.7 22.8 18.8 12.4 9.7 9.6 12.1 12.1 4.7 23.8 33.5 0.5 1.0 1.6 55.8 0.0 2.5 14.7 29.6 1.8 216.0 0.3 6.6 0.4 22.7 0.4 0.7 116.8 0.2 0.2 1.1 1.0 9.3 5.7 0.1 20.6 2.4 2.5 1.2 3.6 0.3 7.9 0.0 0.0 0.6 20.4 0.2 0.9 1.8 0.3 126.2 0.0 0.8 16.1 1.3 1.1 0.2 10.7 0.2 0.9 ACSM1 "BUCS1, MACS1" ENSG00000166743 "Acyl-CoA synthetase medium chain family member 1" Q08AH1 16 20623237-20698890 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "breast: 83.4" "Cell type enhanced" "Detected in many" 10 "Cholangiocytes: 7.6;Early spermatids: 11.5;Late spermatids: 18.5" "Group enriched" "Detected in many" 8 "liver cancer: 14.7;prostate cancer: 36.7" "Cell type enhanced" "Detected in some" "eosinophil: 3.5;memory B-cell: 3.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "NTERA-2: 18.8" "Not detected" "Not detected" HPA046291 Uncertain NA NA "HPA046291: AB_10960704" "unprognostic (1.08e-2)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (5.49e-4)" "unprognostic (1.66e-1)" "unprognostic (3.50e-2)" "unprognostic (9.46e-2)" "unprognostic (3.10e-1)" "unprognostic (8.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (8.24e-2)" "unprognostic (3.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 0.0 0.1 0.0 0.0 0.0 1.1 83.4 0.1 0.1 1.7 0.4 0.2 2.3 0.2 0.1 2.4 0.2 0.1 0.0 0.0 1.2 3.8 0.2 0.1 0.0 2.8 1.4 0.5 0.0 0.0 3.4 0.2 1.2 0.2 0.1 2.2 0.4 0.3 0.0 0.2 2.1 4.5 0.2 0.1 1.1 1.5 3.4 0.0 3.5 0.9 1.3 0.6 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.6 0.0 0.5 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 3.5 0.1 0.2 0.1 3.4 0.6 0.0 0.0 2.9 0.5 0.2 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.6 0.0 0.3 7.6 4.0 1.2 0.0 0.0 0.1 1.7 3.0 11.5 0.7 0.4 0.0 2.0 0.1 0.0 3.1 0.0 0.8 0.2 0.0 1.2 0.6 0.0 18.5 4.0 1.8 0.0 2.8 3.7 0.0 1.5 3.5 6.7 1.2 0.0 0.0 0.0 0.5 0.0 1.4 0.1 0.0 2.2 1.2 ACSM2A "A-923A4.1, ACSM2, MGC150530" ENSG00000183747 "Acyl-CoA synthetase medium chain family member 2A" Q08AH3 16 20451461-20487667 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 90 "kidney: 63.5;liver: 82.6" "Group enriched" "Detected in some" 13 "Hepatocytes: 567.1;Proximal tubular cells: 367.9" "Group enriched" "Detected in some" 479 "liver cancer: 22.7;renal cancer: 25.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Hep G2: 6.6" HPA057699 Supported NA NA "HPA057699: AB_2683506" "unprognostic (1.17e-4)" "prognostic favorable (1.41e-5)" "unprognostic (5.25e-1)" "unprognostic (2.42e-1)" "unprognostic (9.28e-3)" "unprognostic (1.52e-1)" "unprognostic (5.10e-1)" "unprognostic (2.09e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.0 63.5 82.6 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 25.5 0.0 0.2 0.0 0.3 35.7 0.0 0.0 7.0 0.0 0.0 26.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 567.1 0.0 0.0 0.0 21.5 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 367.9 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.0 ACSM2B "ACSM2, HXMA, HYST1046" ENSG00000066813 "Acyl-CoA synthetase medium chain family member 2B" Q68CK6 16 20536226-20576427 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "kidney: 76.1;liver: 93.4" "Group enriched" "Detected in some" 13 "Hepatocytes: 830.9;Proximal tubular cells: 347.6" "Group enriched" "Detected in some" 450 "liver cancer: 30.9;renal cancer: 17.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 5.5;Hep G2: 10.1" HPA057699 Supported NA NA "HPA057699: AB_2683506" "unprognostic (1.34e-2)" "prognostic favorable (3.31e-4)" "unprognostic (7.13e-2)" "unprognostic (2.29e-1)" "unprognostic (6.67e-2)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-2)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 76.1 93.4 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.6 0.9 1.0 0.5 0.2 1.2 0.0 1.0 0.0 5.5 1.5 0.0 0.0 1.4 0.9 0.2 0.0 0.0 1.2 0.9 0.1 2.8 0.0 0.9 0.8 0.0 0.0 0.0 1.0 0.7 0.3 1.3 10.1 0.0 1.3 1.4 0.0 0.0 0.0 0.4 0.8 0.6 0.3 0.9 1.2 0.0 0.7 0.6 1.3 1.2 1.7 0.0 0.1 1.2 0.2 0.4 0.2 1.9 1.0 2.7 0.0 1.0 0.2 2.0 0.4 0.0 0.0 1.0 0.0 0.8 0.8 0.5 0.7 0.7 3.5 1.9 0.5 0.5 0.2 0.6 0.0 0.6 0.1 0.8 0.2 0.1 0.6 0.7 1.2 1.0 0.2 0.1 0.9 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.0 41.9 0.0 0.2 0.0 0.3 28.1 0.0 0.0 7.0 0.0 0.0 29.9 0.1 0.7 0.5 0.0 46.7 0.0 0.0 0.0 0.0 0.0 830.9 0.1 0.0 1.7 23.9 21.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 347.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.6;ovary: 47.7;pancreas: 46.6" "Cell type enhanced" "Detected in many" 8 "Distal tubular cells: 71.3;Ito cells: 98.8;Proximal tubular cells: 77.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 18.3" "Group enriched" "Detected in all" 4 "granulocytes: 18.3;T-cells: 7.4" "Cell line enhanced" "Detected in some" "HEL: 20.3;HMC-1: 85.9;K-562: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain NA NA "HPA041013: AB_10671693" "unprognostic (1.62e-4)" "unprognostic (1.30e-2)" "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "prognostic favorable (1.97e-4)" "unprognostic (3.56e-2)" "unprognostic (1.95e-3)" "prognostic favorable (9.88e-6)" "unprognostic (1.27e-1)" "unprognostic (6.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" 2.1 1.8 0.3 3.7 1.0 3.4 18.6 0.4 0.4 10.9 7.0 0.5 4.3 1.7 10.4 5.3 2.9 11.2 5.0 4.0 0.3 0.3 33.1 58.6 6.4 3.7 0.4 0.3 47.7 46.6 5.1 1.0 1.8 0.7 9.6 7.2 1.4 3.6 6.5 1.0 2.0 3.1 3.2 0.5 1.3 10.9 14.7 0.3 1.5 1.5 1.6 1.8 3.9 6.6 2.2 1.9 18.3 2.9 1.9 7.4 2.3 0.2 2.8 0.5 0.1 0.8 0.5 0.3 0.0 0.3 0.0 0.2 0.2 4.0 0.3 4.5 0.1 0.1 0.3 0.0 0.4 0.3 0.9 1.4 20.3 0.0 1.5 0.3 2.2 85.9 0.8 0.4 0.1 0.4 0.4 0.0 0.1 60.5 3.4 0.0 0.3 0.1 0.7 0.1 3.0 0.7 0.6 0.0 4.3 4.1 0.2 0.1 0.1 0.0 1.2 0.0 0.1 1.3 0.1 0.3 0.2 0.2 0.2 0.1 4.9 3.8 0.2 0.3 1.6 0.1 2.3 1.6 18.3 3.3 1.0 3.8 1.4 4.1 3.0 0.2 2.2 6.5 7.4 0.5 1.9 2.9 1.9 4.6 2.3 0.3 1.0 0.4 0.4 0.3 0.3 0.4 0.3 0.7 0.3 3.0 25.3 23.1 29.1 2.5 0.0 3.2 17.8 2.7 2.3 12.2 0.0 14.9 71.3 44.7 11.7 0.5 3.9 0.0 11.1 1.0 1.5 14.6 0.0 34.1 3.2 0.0 2.4 98.8 6.9 9.1 25.6 1.5 0.0 1.0 9.1 0.0 14.1 11.5 12.0 77.8 0.0 0.0 3.1 2.7 1.0 1.6 16.0 5.7 22.5 4.3 ACSM4 ENSG00000215009 "Acyl-CoA synthetase medium chain family member 4" P0C7M7 12 7304284-7328724 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.0;testis: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.1;HDLM-2: 3.8;Karpas-707: 2.6;NB-4: 4.0;SH-SY5Y: 4.7;U-87 MG: 6.7" "Region enhanced" "Detected in single" "olfactory region: 0.6" "Not detected" "Not detected" HPA049895 Uncertain NA NA "HPA049895: AB_2680940" "unprognostic (9.50e-5)" "unprognostic (5.45e-2)" "unprognostic (4.84e-2)" "unprognostic (6.06e-4)" "unprognostic (1.77e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-3)" "unprognostic (3.31e-3)" "unprognostic (3.85e-2)" "unprognostic (8.78e-2)" "unprognostic (3.27e-1)" "unprognostic (3.60e-1)" "unprognostic (2.45e-9)" "unprognostic (1.82e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.73e-1)" 0.2 0.5 0.1 0.7 0.1 0.0 0.1 0.1 0.6 0.1 0.1 0.9 0.1 0.0 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.0 0.1 2.0 0.1 3.6 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.3 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.5 0.4 0.3 0.0 0.0 0.7 4.7 0.7 1.1 0.0 0.0 0.0 1.5 1.0 0.5 0.4 0.1 0.0 0.1 0.1 0.0 6.7 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 94.6" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 179.6" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.8;intermediate monocyte: 1.9;myeloid DC: 3.2;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 8 "dendritic cells: 3.2;monocytes: 2.8" "Group enriched" "Detected in some" 5 "ASC diff: 5.8;ASC TERT1: 12.6;HSkMC: 15.0;U-87 MG: 9.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 11.1 1.1 1.9 0.7 2.1 0.4 3.2 1.3 1.6 1.0 1.0 2.9 0.0 0.5 0.3 2.8 0.5 0.6 1.0 0.9 3.0 1.9 8.9 94.6 0.9 1.6 2.9 2.1 0.4 1.4 0.4 0.1 0.7 2.0 0.4 0.6 0.5 0.5 0.5 4.4 0.6 0.6 0.5 2.9 1.7 0.9 1.0 3.0 0.1 1.7 0.6 0.4 0.5 0.7 0.3 3.2 0.3 2.8 0.0 0.3 0.5 0.0 0.0 0.1 0.1 5.8 12.6 0.0 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 15.0 0.0 0.8 0.1 0.3 0.0 0.0 0.1 0.6 1.7 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 9.2 0.1 0.0 0.3 2.8 0.1 0.1 1.9 0.1 0.1 0.3 0.2 3.2 0.3 0.2 0.3 0.1 0.0 1.3 0.1 0.0 0.5 1.9 2.1 1.3 1.6 3.0 1.9 2.9 2.1 2.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.7 0.3 0.0 179.6 3.3 0.0 0.0 6.7 8.8 0.2 8.6 1.2 0.0 1.8 0.0 1.1 0.0 0.0 5.6 31.5 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.1 ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228928 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.3;pancreas: 7.3;stomach 1: 6.2" "Group enriched" "Detected in some" 16 "Cone photoreceptor cells: 2.0;Early spermatids: 1.9;Rod photoreceptor cells: 4.6" "Cancer enriched" "Detected in single" 7 "urothelial cancer: 1.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 30 "RT4: 9.2" HPA044593 Uncertain NA NA "HPA044593: AB_10960261" "unprognostic (2.91e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (5.73e-2)" "unprognostic (2.48e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (3.75e-3)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.71e-4)" 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.8 0.4 0.0 6.2 0.3 0.0 16.3 0.8 0.0 0.0 2.5 1.9 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACSS1 "ACAS2L, AceCS2L, dJ568C11.3, MGC33843" ENSG00000154930 "Acyl-CoA synthetase short chain family member 1" Q9NUB1 20 25006230-25058980 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 66.4" "Cell type enhanced" "Detected in many" 14 "Cytotrophoblasts: 211.3;Syncytiotrophoblasts: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 19.6;JURKAT: 20.6;OE19: 25.4;RPMI-8226: 29.2;U-937: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041014, HPA043228" Enhanced NA NA "HPA041014: AB_2677251, HPA043228: AB_2678372" "unprognostic (6.87e-2)" "prognostic favorable (9.37e-4)" "unprognostic (5.32e-2)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (3.03e-2)" "unprognostic (3.20e-3)" "prognostic favorable (8.33e-5)" "unprognostic (2.44e-1)" "unprognostic (2.17e-2)" "unprognostic (2.43e-1)" "unprognostic (7.72e-2)" "unprognostic (4.58e-3)" "unprognostic (5.85e-2)" "unprognostic (2.68e-1)" "unprognostic (3.69e-1)" "unprognostic (1.60e-1)" 6.1 4.8 22.8 8.6 26.6 16.3 9.1 17.1 19.6 9.0 14.0 21.8 9.7 28.1 8.5 12.3 7.5 10.8 12.4 32.4 26.3 9.2 19.5 5.5 10.8 13.4 15.1 20.4 12.3 28.8 9.3 5.7 66.4 21.3 14.8 12.5 9.9 21.8 10.2 19.5 9.3 25.9 8.0 11.1 16.1 26.9 21.6 22.9 11.9 14.9 4.8 12.2 8.7 7.1 7.2 4.4 8.7 6.3 12.6 5.5 2.7 0.0 4.7 1.4 0.0 4.5 1.7 0.1 0.5 2.0 2.0 1.4 4.7 0.6 8.2 0.8 1.9 8.8 2.4 6.9 1.0 0.4 0.0 0.6 14.1 0.1 19.6 4.6 3.3 0.1 2.9 3.5 0.2 0.0 0.0 4.4 20.6 0.7 15.8 0.1 0.5 19.0 5.6 0.1 25.4 7.6 14.9 0.4 29.2 3.0 3.7 3.4 0.1 0.9 1.9 13.1 0.1 9.1 7.5 0.6 0.0 0.0 0.0 0.2 11.0 0.7 0.0 0.2 20.3 5.2 6.3 3.7 8.7 5.5 6.3 4.5 5.2 3.7 4.8 4.4 7.2 3.2 4.9 0.8 12.6 4.1 2.8 3.2 2.7 22.8 26.6 17.1 19.6 26.3 9.2 15.1 20.4 21.3 22.9 11.9 13.7 25.6 6.7 4.6 2.4 60.2 45.9 9.4 9.1 10.4 0.0 211.3 64.6 3.4 72.5 7.1 29.0 23.3 6.7 6.5 11.6 9.5 5.7 5.0 43.5 0.0 0.0 9.2 7.5 14.5 31.9 8.1 6.8 2.8 28.5 14.3 3.0 14.0 30.4 14.0 0.7 19.4 14.4 0.9 1.1 3.8 350.8 23.5 21.3 3.0 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 63.4" "Cell type enhanced" "Detected in all" 5 "Enterocytes: 98.3;Mucus-secreting cells: 80.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 17.0" "Group enriched" "Detected in many" 5 "dendritic cells: 12.6;granulocytes: 17.0;monocytes: 11.6" "Cell line enhanced" "Detected in many" "RPMI-8226: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Cytosol" Vesicles "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 30.3 12.6 2.8 9.2 7.0 1.9 12.4 5.6 7.0 6.8 21.0 10.6 8.3 21.4 6.6 7.0 8.1 4.5 7.7 24.8 2.9 2.5 11.2 15.7 11.7 3.2 6.8 3.2 5.1 3.2 4.7 2.5 4.6 5.5 3.4 10.4 3.5 9.8 6.8 63.4 6.8 24.1 3.0 6.1 2.7 13.4 3.1 7.1 1.1 3.9 7.3 3.0 6.5 6.1 0.7 12.6 17.0 11.6 0.3 3.0 4.7 11.9 1.6 1.2 1.6 8.5 9.0 12.4 7.1 5.5 2.0 3.5 4.3 6.6 0.0 8.1 3.1 7.7 9.0 2.9 17.9 1.5 0.1 2.8 16.6 0.8 2.0 6.2 1.6 9.1 6.1 3.9 2.9 2.8 2.9 3.1 1.2 10.5 1.3 2.7 1.4 0.5 7.3 0.8 3.6 20.3 4.4 7.8 26.2 6.8 1.2 1.1 5.4 8.7 6.4 6.9 3.4 3.1 3.6 11.7 2.4 3.3 4.3 2.3 11.3 8.2 3.8 6.7 2.6 1.9 17.0 11.6 3.0 0.6 7.2 0.5 0.4 1.6 0.7 12.6 0.7 3.0 1.5 6.5 0.3 3.4 2.1 1.1 4.7 2.8 7.0 5.6 7.0 2.9 2.5 6.8 3.2 5.5 7.1 11.9 40.9 3.0 8.5 6.9 6.0 70.4 25.5 5.3 13.6 10.4 5.9 13.6 10.0 16.5 7.2 13.2 98.3 23.3 29.5 8.5 8.9 8.8 9.2 44.8 14.7 7.9 7.5 10.4 17.2 6.0 10.6 13.8 13.5 19.8 80.6 8.8 18.1 60.0 4.2 51.2 3.4 12.9 9.9 11.6 7.3 9.5 17.5 5.0 60.0 8.9 ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261205 "Enzymes, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 2: 42.8;Hepatocytes: 47.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 8.3;neutrophil: 6.0" "Lineage enriched" "Detected in single" 71 "granulocytes: 8.3" "Cell line enhanced" "Detected in many" "ASC diff: 9.4;ASC TERT1: 10.7;Hep G2: 26.5;hTERT-RPE1: 9.1;RH-30: 12.3;SK-BR-3: 11.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" 19.6 18.3 7.4 1.9 8.3 1.0 8.1 2.7 7.7 13.2 2.6 5.5 10.8 1.2 18.2 14.4 2.0 8.3 8.1 10.9 6.4 3.9 24.4 37.1 8.8 1.7 7.4 6.5 16.7 2.6 21.3 11.0 4.1 6.5 7.1 1.6 10.3 20.4 11.4 9.8 2.1 1.9 6.6 5.5 2.8 1.9 4.0 4.1 0.0 9.2 2.9 1.6 3.5 6.3 0.0 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.1 2.2 0.0 9.4 10.7 0.0 1.5 7.0 1.1 1.2 0.3 0.0 0.1 0.0 3.1 3.3 0.1 0.0 0.0 0.7 0.0 1.7 0.0 0.1 26.5 3.2 0.3 0.0 7.2 0.0 0.3 0.0 9.1 0.2 0.0 0.0 0.0 5.0 0.6 0.0 0.1 3.2 0.0 0.0 0.0 12.3 1.7 0.0 0.0 2.1 0.0 0.0 11.6 0.0 4.8 5.2 0.3 0.0 1.9 1.8 0.2 0.7 0.1 0.1 0.0 2.3 0.0 2.1 8.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.1 0.0 7.4 8.3 2.7 7.7 6.4 3.9 7.4 6.5 6.5 4.1 20.8 42.8 0.0 7.0 0.8 31.6 19.3 15.3 6.7 5.7 12.2 3.9 1.3 5.0 4.0 33.3 1.0 0.0 0.0 2.6 0.6 4.3 4.4 0.0 47.4 0.6 27.0 0.0 3.1 2.4 6.4 22.2 0.4 0.0 0.0 0.0 19.7 0.2 0.0 22.3 26.7 4.5 6.5 5.7 4.2 0.5 0.1 0.5 0.0 0.0 2.0 ADSS ENSG00000035687 "Adenylosuccinate synthase" P30520 1 244408494-244452134 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024400 Supported Supported "Plasma membrane,Cytosol" NA NA 620000 Cytosol "Plasma membrane" "HPA024400: AB_1844623" "unprognostic (4.24e-3)" "unprognostic (2.63e-1)" "unprognostic (3.95e-2)" "unprognostic (8.68e-2)" "unprognostic (6.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.35e-1)" "unprognostic (7.62e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" 19.4 17.8 23.2 23.8 31.2 29.2 26.3 18.3 26.3 20.9 20.9 35.9 27.1 21.1 18.9 23.3 27.7 18.3 15.8 9.8 24.9 23.4 25.1 19.3 19.2 21.2 42.5 16.6 20.9 21.2 26.6 17.7 21.0 34.9 19.8 22.7 13.1 25.0 21.7 11.0 26.5 23.2 22.9 29.3 24.9 24.7 48.9 36.7 26.7 26.3 17.9 24.8 26.5 21.8 10.9 13.6 24.6 21.3 15.5 16.0 11.9 25.7 14.2 12.4 10.9 14.6 20.9 22.9 26.0 21.9 18.7 14.2 18.7 24.9 23.0 17.3 20.0 8.0 19.5 13.5 17.0 21.0 17.0 24.0 15.3 14.2 14.1 17.5 36.2 19.8 14.3 20.6 17.4 17.6 21.8 66.6 12.7 26.5 17.1 18.5 6.1 23.2 24.3 33.0 24.6 15.7 21.5 11.8 24.8 31.0 16.0 16.9 14.8 22.1 20.6 26.0 13.8 14.3 19.3 29.1 17.3 9.5 20.0 27.0 20.8 27.2 17.4 14.3 42.5 25.5 24.6 15.8 13.0 15.0 20.5 16.0 10.9 13.7 12.8 13.6 8.6 11.8 13.3 11.9 15.5 21.3 5.5 14.7 11.9 23.2 31.2 18.3 26.3 24.9 23.4 42.5 16.6 34.9 36.7 44.7 30.5 40.0 44.7 90.9 12.4 5.8 35.7 127.2 85.3 57.6 5.9 47.0 74.6 41.2 102.9 33.7 30.0 0.0 44.0 83.0 35.8 40.9 28.9 29.6 33.8 9.5 17.3 37.4 38.1 103.8 17.5 51.2 40.5 37.9 29.4 34.0 38.5 21.0 15.9 57.5 7.2 12.9 34.0 104.8 68.7 86.1 45.2 60.6 38.1 62.8 ADSSL1 FLJ38602 ENSG00000185100 "Adenylosuccinate synthase like 1" Q8N142 14 104724186-104747325 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 200.5;tongue: 53.2" "Cell type enhanced" "Detected in many" 21 "Cardiomyocytes: 119.6;Early spermatids: 397.7;Late spermatids: 83.9;Muller glia cells: 76.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 12.0;MCF7: 10.6;OE19: 17.0;SiHa: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 220000 "unprognostic (2.23e-2)" "unprognostic (3.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.14e-2)" "unprognostic (2.81e-3)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (2.26e-1)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (2.33e-1)" "unprognostic (2.35e-1)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" 2.5 1.1 0.8 0.5 1.8 0.4 0.9 0.3 1.2 0.8 0.7 3.4 0.3 0.8 0.9 3.5 3.9 1.5 2.2 27.8 1.2 1.5 2.9 7.2 0.7 0.5 3.3 0.4 0.8 1.7 1.9 2.2 1.6 2.0 1.9 0.6 4.6 3.2 1.1 200.5 1.3 0.8 1.0 2.1 0.5 1.2 3.4 2.0 0.0 1.7 53.2 2.8 6.1 3.8 0.0 0.4 1.2 2.1 0.0 0.5 0.0 0.1 2.5 1.8 5.5 1.3 0.8 0.6 0.7 1.0 0.2 0.5 0.2 1.9 0.0 12.0 0.6 0.4 1.0 0.1 0.4 0.4 0.8 0.4 0.0 5.9 0.8 1.4 0.0 4.7 2.6 1.8 0.0 2.0 2.1 0.3 0.2 2.1 0.0 0.9 10.6 0.0 0.5 1.6 17.0 1.1 0.1 0.2 0.6 0.4 1.3 1.6 3.3 17.8 0.8 2.4 1.5 5.6 1.5 0.6 0.1 0.5 1.2 0.0 3.5 2.5 0.0 1.7 0.8 1.2 0.0 0.1 1.2 0.5 2.1 0.0 0.0 0.1 0.4 0.4 0.0 0.4 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.8 1.8 0.3 1.2 1.2 1.5 3.3 0.4 2.0 2.0 3.0 0.3 0.0 5.2 4.6 3.5 119.6 2.5 14.7 2.3 3.5 0.0 2.8 6.6 2.1 397.7 3.1 3.2 0.0 4.3 1.4 4.7 3.6 0.0 12.8 3.0 4.8 9.2 7.4 2.2 83.9 8.1 2.6 10.1 1.8 2.5 76.5 2.0 3.5 17.3 14.6 2.6 12.9 3.1 35.8 21.6 5.3 1.3 1.7 1.7 7.1 ASNS ENSG00000070669 "Asparagine synthetase (glutamine-hydrolyzing)" P08243 7 97852118-97872542 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" Ligase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 68.0" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 197.3;Erythroid cells: 93.5;Late spermatids: 147.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 8.6;T-cells: 13.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004924, HPA029318, HPA064737" Approved Enhanced Cytosol No No Cytosol "HPA004924: AB_2667295, HPA029318: AB_10602389, HPA064737: AB_2685341" "unprognostic (3.93e-2)" "unprognostic (2.51e-1)" "unprognostic (6.70e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.79e-5)" "prognostic unfavorable (9.42e-6)" "unprognostic (2.28e-2)" "unprognostic (9.08e-2)" "unprognostic (1.89e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-3)" "prognostic unfavorable (6.21e-7)" "unprognostic (5.33e-1)" "unprognostic (2.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.33e-1)" 6.5 7.5 15.9 10.9 21.4 7.6 9.9 31.7 32.3 5.7 10.1 9.4 5.6 6.5 10.0 19.9 10.2 6.9 6.8 9.2 24.5 20.4 6.5 5.9 9.6 16.0 16.3 13.4 19.2 68.0 16.7 16.7 3.2 35.9 9.2 12.7 4.4 49.9 9.3 3.5 13.6 7.8 11.3 20.6 11.0 20.8 16.9 9.2 3.6 16.7 8.2 15.0 9.6 6.6 8.6 1.4 1.5 1.2 2.2 13.2 3.2 19.0 7.3 7.4 60.1 5.9 8.3 18.1 14.1 9.0 6.7 20.2 9.4 7.6 15.0 7.1 28.7 14.0 8.7 19.1 22.3 16.1 18.7 14.1 4.8 3.7 7.0 54.3 30.6 13.5 16.3 75.0 8.8 54.5 3.6 5.5 14.1 26.8 53.3 10.6 40.3 0.9 8.1 10.1 45.6 20.0 2.3 1.4 39.3 4.3 3.7 32.3 24.3 3.6 19.6 76.0 9.9 8.3 21.5 1.4 3.3 22.1 8.8 6.6 63.1 31.5 57.1 41.8 13.9 32.1 1.5 0.3 0.5 3.8 1.2 4.9 8.6 7.4 3.4 1.4 6.2 10.2 5.5 1.5 2.2 0.8 0.1 13.2 3.2 15.9 21.4 31.7 32.3 24.5 20.4 16.3 13.4 35.9 9.2 8.9 4.5 3.7 18.8 11.0 20.1 5.9 12.7 1.4 3.4 8.7 23.6 2.0 6.6 34.4 197.3 3.1 1.7 93.5 52.9 7.7 6.6 17.6 8.1 1.6 1.0 23.8 23.4 2.5 0.6 147.0 8.9 1.8 8.5 11.8 12.9 8.5 38.4 11.9 8.9 3.1 25.4 6.5 12.3 2.3 7.0 9.5 4.7 13.3 7.9 15.2 ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444929-130501274 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 121.5;liver: 309.9" "Cell type enhanced" "Detected in many" 10 "Enterocytes: 457.5;Hepatocytes: 809.9;Proximal tubular cells: 889.6;Urothelial cells: 385.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 4.6" "Lineage enriched" "Detected in single" 46 "dendritic cells: 4.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 87.4;HaCaT: 82.8;hTCEpi: 80.5;RPMI-8226: 134.1;THP-1: 100.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA020896, HPA020934" Enhanced Approved Nucleoplasm,Cytosol No No 4500000 Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" 20.6 15.4 4.6 7.1 4.1 0.0 15.7 2.3 5.4 8.3 18.5 3.5 33.9 11.9 12.0 12.6 9.4 16.6 14.0 11.4 3.8 5.7 121.5 309.9 8.0 2.2 3.2 4.3 11.4 7.9 0.5 4.6 8.7 4.5 12.1 16.8 10.7 26.3 40.6 7.4 12.5 26.8 5.9 3.4 2.7 5.2 8.7 2.2 0.8 17.5 7.0 4.5 17.7 8.6 0.0 4.6 0.0 0.0 0.0 0.0 0.0 11.7 1.1 1.3 2.2 8.9 22.7 4.3 14.0 87.4 2.8 8.5 5.0 3.3 0.0 9.5 28.9 0.8 82.8 5.8 0.5 1.9 2.0 2.6 0.0 1.8 12.8 31.0 1.7 0.1 15.0 80.5 4.5 8.1 0.0 0.1 37.6 0.4 52.2 2.8 58.1 0.6 24.5 1.8 60.2 2.6 0.1 1.5 134.1 7.6 5.8 33.8 0.5 50.0 52.7 3.9 5.4 36.2 100.4 0.0 1.1 7.0 0.2 1.2 8.7 8.3 2.9 22.0 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 4.6 4.1 2.3 5.4 3.8 5.7 3.2 4.3 4.5 2.2 23.8 25.8 33.7 45.3 62.6 0.0 5.0 94.3 20.1 50.0 45.4 0.0 159.6 112.7 79.7 0.8 23.2 457.5 0.0 98.3 5.0 15.7 85.0 5.7 809.9 12.7 0.0 11.5 35.0 18.0 2.7 28.7 2.6 3.3 2.8 129.1 4.8 73.5 143.8 117.4 889.6 0.3 0.0 10.8 1.1 2.0 15.3 120.5 12.5 77.1 385.2 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm No No 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.3 23.0 10.2 20.5 16.7 13.7 8.1 10.8 7.5 13.6 9.7 26.0 10.1 22.7 9.8 9.8 10.5 14.4 30.1 14.3 10.3 14.8 24.3 32.4 17.5 13.5 8.3 25.5 16.4 10.4 11.8 19.8 22.6 6.3 14.6 21.1 22.8 12.7 12.0 25.5 16.2 38.0 24.6 10.7 17.5 28.5 30.7 23.6 10.1 13.0 20.6 10.3 15.0 10.7 12.6 7.9 8.4 10.7 13.1 20.7 17.1 16.1 21.6 26.4 16.9 46.4 8.3 24.6 17.8 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 3.0 3.8 2.2 3.7 3.3 8.9 4.8 15.3 2.7 5.7 1.8 15.7 4.7 0.0 6.1 1.1 3.8 2.5 0.0 3.0 4.7 5.0 2.4 4.6 4.9 6.9 6.4 6.3 4.3 2.4 1.4 5.8 2.2 3.3 5.4 5.2 4.1 5.3 0.0 9.2 1.3 6.2 0.0 5.1 4.9 10.0 3.0 1.8 4.5 6.8 2.0 CARNS1 "ATPGD1, KIAA1394" ENSG00000172508 "Carnosine synthase 1" A5YM72 11 67414968-67425607 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "brain: 88.7;skeletal muscle: 64.8" "Cell type enhanced" "Detected in some" 21 "Alveolar cells type 1: 3.0;Cardiomyocytes: 11.7;Intestinal endocrine cells: 2.9" "Group enriched" "Detected in many" 5 "glioma: 4.1;thyroid cancer: 10.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 20 "B-cells: 1.9;NK-cells: 1.3;T-cells: 3.2" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 13.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA038569 Enhanced "Intracellular and membrane" NA NA "HPA038569: AB_2676089" "unprognostic (1.07e-4)" "unprognostic (4.33e-3)" "unprognostic (2.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (7.54e-3)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (6.14e-6)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.83e-3)" "unprognostic (8.33e-2)" 2.9 1.3 9.2 1.5 24.3 1.5 1.2 3.0 23.9 1.3 1.4 88.7 0.0 1.5 1.2 2.5 2.0 1.5 1.6 5.3 19.7 10.2 1.2 1.3 1.5 2.1 36.9 14.5 1.4 1.6 2.0 0.4 1.1 30.6 1.8 1.3 0.0 1.3 1.3 64.8 1.3 1.9 1.3 51.1 1.8 2.1 1.1 28.1 0.0 2.3 0.9 1.6 1.1 0.3 1.9 0.1 0.0 0.0 1.3 3.2 0.9 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.3 0.5 0.7 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.8 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.4 0.1 0.1 1.0 0.6 0.2 0.2 0.0 0.1 0.1 13.1 0.0 0.0 0.1 0.2 0.1 0.8 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.0 1.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 2.9 0.0 1.4 1.7 1.0 3.1 0.1 1.9 1.3 3.2 0.0 1.3 0.0 0.0 0.7 0.9 9.2 24.3 3.0 22.2 19.7 10.2 36.9 14.5 30.6 28.1 3.0 0.3 1.5 0.1 0.2 0.0 11.7 0.0 1.4 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.2 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.5 0.0 1.7 0.0 0.2 0.6 0.0 1.3 0.0 0.0 CARS CARS1 ENSG00000110619 "Cysteinyl-tRNA synthetase" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Ciliated cells: 92.3;Early spermatids: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 110000 Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 24.9 15.9 15.8 15.8 17.7 9.0 15.9 9.5 29.1 13.4 16.3 19.1 11.1 15.9 14.0 10.7 16.0 10.8 14.2 12.5 15.3 18.7 10.7 22.1 15.1 17.2 23.3 15.9 14.5 42.5 14.9 15.9 14.0 23.0 10.8 17.6 7.4 20.3 14.8 24.6 18.8 17.8 21.0 16.1 14.8 22.8 13.4 17.3 9.8 23.0 14.5 22.7 14.4 19.4 8.3 13.3 18.0 23.9 16.4 18.1 11.6 7.4 3.8 4.9 14.8 19.3 17.8 4.4 19.1 21.8 13.2 23.9 9.3 17.9 11.6 5.6 24.1 0.0 19.2 16.2 21.7 18.2 33.8 3.7 6.5 6.5 7.1 46.3 13.5 14.4 29.3 17.1 11.4 12.7 0.0 17.4 28.8 10.9 41.0 13.0 11.3 9.5 0.0 18.5 26.5 6.8 4.6 8.2 14.5 0.0 12.5 10.6 14.1 4.7 13.4 20.9 3.8 0.0 0.0 6.0 5.4 5.1 13.5 0.2 30.5 27.8 7.4 0.0 7.1 10.7 7.7 12.0 8.8 15.2 10.5 13.0 8.3 13.6 13.6 13.3 6.0 7.5 12.1 18.0 16.4 23.9 5.2 18.1 11.6 15.8 17.7 9.5 29.1 15.3 18.7 23.3 15.9 23.0 17.3 17.9 31.5 21.7 25.4 12.8 11.7 6.7 2.5 92.3 27.3 10.4 5.9 18.8 8.3 35.4 93.7 13.7 18.6 0.0 34.2 34.8 12.6 16.1 20.7 16.8 18.9 14.3 18.3 13.5 15.1 39.9 11.5 14.7 8.5 14.4 16.9 10.8 37.5 21.0 18.0 13.4 10.0 6.5 14.1 39.5 24.2 10.5 27.0 24.2 14.3 35.5 CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Late spermatids: 173.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-87 MG: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA041776: AB_2677666" "unprognostic (2.34e-3)" "unprognostic (9.50e-2)" "unprognostic (6.62e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.98e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (7.82e-2)" "unprognostic (2.11e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.73e-2)" "unprognostic (3.42e-1)" "unprognostic (3.21e-1)" "unprognostic (1.71e-2)" 19.6 28.1 11.9 24.8 13.0 25.6 37.1 18.2 14.5 21.8 20.2 17.6 21.2 17.8 18.5 23.0 20.2 16.8 26.9 26.0 9.9 10.3 17.0 21.4 19.9 26.7 11.3 14.1 17.6 31.7 11.5 19.7 12.5 11.7 17.5 15.0 16.6 19.0 21.3 39.7 16.1 20.1 22.1 11.7 19.7 17.9 11.2 11.4 21.8 19.2 18.5 21.9 16.9 16.7 3.4 4.0 3.1 6.8 0.6 2.2 1.7 35.4 11.8 6.8 16.5 18.1 17.0 9.2 15.8 14.5 16.0 19.7 16.6 16.0 16.6 22.2 17.2 24.4 18.9 11.6 19.8 13.1 15.1 19.3 10.3 25.0 18.9 18.5 25.2 12.6 21.2 15.8 13.9 16.8 11.4 11.4 12.6 7.1 5.2 22.5 8.2 11.2 8.2 5.7 27.2 11.7 16.6 5.0 6.8 17.1 10.4 12.1 9.2 12.7 19.7 18.2 7.6 9.5 28.1 10.2 13.4 5.0 16.9 15.8 9.4 10.7 9.6 65.5 15.1 13.2 0.0 4.7 0.7 2.0 5.1 2.2 3.4 0.6 0.8 4.0 1.4 2.0 1.0 3.1 0.6 6.8 3.4 0.7 1.7 11.9 13.0 18.2 14.5 9.9 10.3 11.3 14.1 11.7 11.4 8.9 15.7 17.6 19.1 11.4 22.3 34.3 12.7 2.7 7.9 26.2 23.6 21.5 43.1 14.9 53.5 10.8 19.0 0.0 4.1 25.5 14.3 16.8 16.1 23.1 25.1 22.3 18.0 9.8 26.7 173.5 19.0 29.2 11.8 13.6 17.0 23.0 12.9 7.0 17.0 29.6 24.7 6.5 18.6 7.2 4.7 11.8 14.1 12.9 22.3 18.2 CPS1 ENSG00000021826 "Carbamoyl-phosphate synthase 1" P31327 2 210477682-210679107 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Urea cycle" "Allosteric enzyme, Ligase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 298.3" "Cell type enriched" "Detected in many" 72 "Hepatocytes: 1670.2" "Cancer enriched" "Detected in many" 8 "liver cancer: 136.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 90.5;SK-BR-3: 27.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB003781, HPA021400" Enhanced Supported "Nucleoli,Nucleoli rim" NA NA 2100000 "Nucleoli, Nucleoli rim" "CAB003781: , HPA021400: AB_1847197" "unprognostic (1.67e-2)" "unprognostic (3.72e-2)" "unprognostic (4.02e-2)" "unprognostic (7.21e-7)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "prognostic favorable (6.93e-5)" "unprognostic (1.23e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-2)" "unprognostic (5.38e-2)" "unprognostic (1.94e-3)" "unprognostic (2.38e-4)" "unprognostic (5.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.14e-2)" "unprognostic (3.74e-2)" 0.4 0.1 0.5 0.3 1.6 0.0 0.8 0.3 0.7 0.4 0.2 0.7 0.3 31.5 0.3 0.7 0.5 0.2 0.4 0.3 0.5 0.4 0.6 298.3 0.2 0.3 1.5 0.8 0.7 0.2 0.0 0.4 1.1 1.4 0.3 0.0 0.6 0.2 0.2 0.3 0.3 17.2 0.4 2.3 0.3 0.2 1.3 0.5 0.0 0.4 0.4 0.1 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2.4 6.3 4.3 4.2 7.4 6.7 2.3 2.7 2.7 4.2 0.6 0.0 1.0 0.1 2.5 3.8 1.1 0.2 3.8 6.8 0.0 1.9 4.0 90.5 5.6 1.4 2.1 0.0 3.8 2.8 5.3 5.4 6.9 0.3 1.7 4.0 0.3 4.4 1.1 0.1 0.2 2.4 0.0 0.6 0.2 5.8 0.5 5.7 0.0 0.1 0.4 15.8 27.3 3.0 8.5 0.0 0.7 3.0 7.0 2.1 2.1 4.9 0.0 0.3 0.0 4.6 4.4 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.3 0.7 0.5 0.4 1.5 0.8 1.4 0.5 11.9 9.6 20.7 0.5 1.9 1.1 0.7 15.3 1.4 6.8 1.8 7.9 0.3 0.0 0.1 23.2 1.4 0.3 23.3 0.2 0.4 2.5 1.2 3.5 1670.2 0.2 0.0 0.0 16.5 22.7 3.6 2.3 1.8 1.7 0.0 0.1 1.4 0.0 0.0 1.1 0.7 2.2 0.0 2.5 0.3 1.1 1.6 17.4 5.0 0.1 0.4 CTPS1 "CTPS, GATD5" ENSG00000171793 "CTP synthase 1" P17812 1 40979335-41012565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017111, HPA051322" Enhanced Approved "Actin filaments,Cytosol" NA Yes Cytosol "Actin filaments" "CAB017111: , HPA051322: AB_2681441" "unprognostic (6.60e-2)" "unprognostic (4.44e-2)" "unprognostic (3.21e-2)" "unprognostic (2.00e-3)" "unprognostic (2.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.42e-2)" "unprognostic (9.72e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-1)" "unprognostic (8.21e-3)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" "unprognostic (1.89e-2)" 7.1 10.0 4.5 10.8 7.8 9.7 5.1 5.9 9.8 14.4 23.6 5.8 16.3 4.3 25.9 8.4 11.3 21.9 13.4 6.7 4.7 5.1 8.6 26.4 7.0 9.4 7.9 4.7 10.1 6.3 16.8 5.4 7.7 6.2 14.4 9.8 9.1 56.5 19.6 13.2 5.8 13.5 35.8 5.1 7.5 9.0 11.8 6.7 14.6 4.5 11.3 13.2 21.3 9.5 6.0 12.8 0.0 7.3 6.6 7.0 3.8 21.2 19.5 27.6 22.2 7.6 9.5 43.4 37.4 16.1 41.1 27.7 38.3 18.9 39.9 17.0 17.1 11.3 15.0 29.5 27.9 41.1 16.7 22.4 24.4 26.0 12.1 25.0 32.5 19.2 10.4 15.1 42.5 30.6 7.2 18.6 29.3 24.5 17.6 28.7 11.9 35.1 12.1 37.7 17.8 23.2 27.1 33.5 25.8 20.7 19.4 37.1 18.1 23.3 25.1 9.3 28.3 8.7 45.0 15.2 27.2 35.6 18.3 46.4 11.4 13.3 35.5 17.8 25.9 28.3 0.0 4.0 0.0 4.6 7.3 6.6 6.0 5.3 4.8 12.0 3.9 4.4 7.0 0.0 6.6 6.1 12.8 6.6 3.8 4.5 7.8 5.9 9.8 4.7 5.1 7.9 4.7 6.2 6.7 6.0 20.2 17.3 10.5 7.1 9.9 4.2 20.4 2.7 5.7 5.2 5.9 14.6 1.7 15.2 22.6 7.3 2.8 0.0 15.1 21.5 6.6 4.3 1.1 24.5 9.6 11.1 2.9 2.5 2.4 21.2 10.0 6.0 1.7 12.6 2.6 5.2 14.2 0.0 23.3 9.6 4.2 38.8 14.4 9.3 42.5 6.5 4.7 5.7 5.2 5.8 CTPS2 ENSG00000047230 "CTP synthase 2" Q9NRF8 X 16588003-16712936 "Enzymes, Predicted intracellular proteins" "Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017437, HPA075930" Uncertain Approved Mitochondria,Cytosol NA NA 14000 "Mitochondria, Cytosol" "HPA017437: AB_1847326, HPA075930: " "unprognostic (1.40e-1)" "unprognostic (6.69e-2)" "unprognostic (3.37e-2)" "unprognostic (7.38e-2)" "unprognostic (1.05e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (6.57e-3)" "unprognostic (8.52e-2)" "unprognostic (4.31e-3)" "unprognostic (4.43e-1)" "unprognostic (1.89e-2)" "unprognostic (7.22e-2)" "unprognostic (6.04e-2)" "unprognostic (8.93e-2)" "unprognostic (5.04e-2)" "prognostic favorable (4.56e-4)" 10.0 12.0 7.8 11.5 11.9 7.8 13.5 14.3 9.9 17.5 13.3 14.8 10.8 15.6 22.0 10.2 9.6 12.1 11.9 7.2 8.6 7.1 8.1 13.4 8.3 7.9 9.1 6.1 17.9 14.9 22.9 8.5 8.3 9.3 12.8 12.6 14.1 11.8 9.7 5.5 9.2 12.8 14.0 12.3 7.1 11.3 4.4 10.8 11.5 11.8 8.4 10.6 11.8 11.2 1.6 3.3 1.1 6.1 3.8 2.4 1.4 7.6 7.0 11.4 9.5 5.8 4.4 0.1 4.2 3.5 6.8 6.3 7.0 8.0 0.2 13.5 4.3 6.2 6.2 16.0 7.7 8.2 0.0 10.6 4.3 9.8 10.2 3.0 3.1 0.1 4.8 2.6 6.4 5.4 7.7 9.1 0.1 6.1 0.3 6.2 10.1 0.1 2.4 19.6 2.8 8.2 0.1 6.6 2.4 7.3 8.5 7.1 13.1 13.3 1.0 7.6 12.9 18.5 8.9 5.8 3.6 1.9 9.4 3.6 0.2 0.1 25.3 2.8 2.7 3.9 0.4 1.5 1.1 1.3 0.8 2.4 1.6 2.2 1.4 3.3 1.4 1.7 1.7 0.1 3.8 6.1 2.2 2.0 1.4 7.8 11.9 14.3 9.9 8.6 7.1 9.1 6.1 9.3 10.8 8.9 7.0 3.7 5.0 2.9 4.9 5.2 10.2 4.0 9.1 5.2 0.0 2.9 3.3 8.7 2.8 4.9 6.0 0.0 8.4 6.2 3.9 4.8 5.8 7.5 4.5 6.4 10.9 6.7 4.9 5.8 8.3 2.6 8.5 9.0 7.4 3.4 10.3 11.0 3.9 2.2 4.4 6.5 4.1 0.0 0.2 3.3 1.3 3.8 8.1 4.8 DARS ENSG00000115866 "Aspartyl-tRNA synthetase" P14868 2 135906677-135986100 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol NA NA 160000 Cytosol "HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994" "unprognostic (6.13e-2)" "unprognostic (8.16e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (2.39e-6)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.57e-4)" "unprognostic (6.00e-3)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.04e-1)" "unprognostic (9.12e-2)" "unprognostic (3.94e-3)" "unprognostic (2.00e-1)" 30.3 29.7 35.0 27.6 35.5 19.7 34.9 18.0 28.3 27.6 25.4 25.6 26.9 14.8 30.1 26.7 44.4 26.9 19.6 29.8 29.0 28.8 34.6 35.5 19.7 32.3 32.1 25.6 34.0 27.0 26.4 24.5 31.7 23.8 31.0 20.3 20.6 26.6 28.3 45.1 30.6 21.4 42.4 33.8 29.8 23.6 12.8 25.0 42.0 33.0 33.1 36.7 45.3 30.2 48.6 30.5 11.2 18.8 36.6 42.7 30.6 47.9 19.7 16.8 17.8 18.8 23.6 38.6 24.0 26.9 26.3 25.8 42.5 20.9 56.0 37.6 19.7 19.2 27.7 25.8 31.0 47.8 25.6 23.1 34.1 19.5 44.1 24.3 45.5 22.7 22.7 25.1 29.3 26.5 33.6 14.5 26.3 36.5 17.9 21.8 22.5 34.9 39.2 19.8 19.5 18.8 42.6 36.6 39.1 31.6 18.7 12.0 22.8 18.4 16.7 18.7 18.0 18.3 32.5 10.8 23.0 23.0 16.9 23.8 49.3 26.8 60.2 36.2 34.7 14.2 6.0 18.8 11.2 27.5 18.3 41.2 48.6 41.3 36.0 30.5 43.8 42.7 37.0 7.3 36.6 14.0 29.2 36.9 30.6 35.0 35.5 18.0 23.8 29.0 28.8 32.1 25.6 23.8 25.0 56.6 49.0 70.0 90.1 67.0 59.0 74.7 38.2 48.2 51.2 43.6 31.4 98.6 77.9 93.1 1.7 54.2 20.6 23.3 71.9 123.6 68.6 66.4 31.2 58.6 82.4 50.9 37.0 53.4 79.2 4.0 64.2 52.3 59.1 111.0 39.3 83.6 78.4 23.0 72.2 75.2 23.7 51.8 71.3 25.1 45.4 63.2 114.1 63.3 53.4 76.3 DARS2 FLJ10514 ENSG00000117593 "Aspartyl-tRNA synthetase 2, mitochondrial" Q6PI48 1 173824503-173858546 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Erythroid cells: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026506, HPA026528" Enhanced Supported Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "HPA026506: AB_1847482, HPA026528: AB_1847483" "unprognostic (3.14e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-3)" "unprognostic (4.10e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (6.17e-2)" "unprognostic (1.15e-1)" "prognostic favorable (1.74e-4)" "unprognostic (3.30e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (4.73e-3)" 17.0 22.2 6.3 10.1 8.1 5.4 9.0 7.5 8.6 7.8 15.1 6.7 8.3 11.7 10.4 6.1 13.4 6.4 5.9 11.2 5.5 6.0 21.9 14.8 8.2 11.0 6.4 4.2 9.5 14.9 18.1 15.3 10.9 10.0 8.5 16.6 10.2 10.2 6.2 10.6 6.0 16.1 6.2 9.0 11.4 11.3 8.4 6.9 26.1 12.2 6.3 12.5 9.7 8.1 9.3 9.0 4.8 10.7 5.0 9.3 5.2 29.0 19.4 12.1 7.5 9.2 13.1 15.5 12.8 10.6 18.5 14.2 18.2 26.1 15.7 17.5 10.2 12.2 29.8 33.4 21.6 25.3 17.9 16.4 13.6 9.7 12.6 9.0 11.5 12.4 9.5 9.9 18.7 19.1 5.9 18.4 11.9 27.5 12.4 15.4 8.0 14.6 6.5 23.4 32.5 17.4 17.2 15.4 28.9 16.8 9.7 15.9 14.5 14.0 31.3 20.2 19.0 32.8 15.2 8.1 9.5 15.0 13.1 20.4 9.7 24.5 18.2 5.5 12.7 20.5 4.4 7.0 4.8 6.6 10.7 9.3 9.3 7.2 5.8 9.0 7.3 7.7 4.8 0.7 5.0 7.4 3.7 5.1 5.2 6.3 8.1 7.5 8.6 5.5 6.0 6.4 4.2 10.0 6.9 3.0 1.9 4.3 3.6 1.5 2.2 10.5 7.6 1.4 3.4 5.2 0.0 7.3 6.6 3.9 1.9 3.2 4.5 23.3 2.3 13.0 3.4 2.3 5.7 4.3 8.9 3.2 4.1 1.3 3.5 1.0 2.8 5.0 1.7 6.4 5.0 2.4 3.6 0.0 1.4 6.4 2.7 0.0 2.3 5.7 6.4 1.4 3.5 2.9 6.0 2.5 DPH6 "ATPBD4, MGC14798" ENSG00000134146 "Diphthamine biosynthesis 6" Q7L8W6 15 35217345-35546193 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042976, HPA055496" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042976: AB_10964890, HPA055496: AB_2682835" "unprognostic (9.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (9.94e-2)" "unprognostic (1.76e-1)" "unprognostic (1.49e-3)" "unprognostic (7.92e-3)" "unprognostic (1.13e-1)" "unprognostic (4.65e-6)" "unprognostic (9.70e-2)" "unprognostic (5.61e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" 13.3 12.7 8.0 6.8 16.1 6.4 15.3 11.6 15.8 14.7 9.2 15.5 10.8 8.5 23.9 17.1 14.7 11.5 10.5 14.4 7.8 7.2 14.7 11.2 8.7 9.3 9.7 12.0 16.7 19.5 15.8 31.7 11.1 13.4 8.5 10.2 14.6 11.5 14.7 24.9 15.2 8.7 16.8 11.1 8.3 9.6 11.3 10.6 7.1 15.3 16.5 10.0 11.0 11.3 8.4 6.3 0.3 6.5 13.2 10.8 4.4 10.5 5.7 9.6 8.1 1.7 7.9 9.4 4.0 7.0 9.7 5.1 7.6 9.9 3.3 9.8 3.7 11.8 12.2 11.1 11.5 11.6 2.6 7.0 12.3 6.5 12.0 10.3 6.5 8.0 6.6 14.6 3.9 18.9 6.0 9.3 7.1 13.5 13.4 8.9 4.1 8.0 6.1 8.5 16.1 5.3 10.0 9.0 4.5 8.4 13.5 7.0 6.9 7.5 8.4 6.4 5.9 29.0 9.1 2.8 9.5 9.2 9.4 6.3 12.0 19.0 8.3 8.2 11.3 9.0 0.0 6.5 0.3 6.2 6.0 7.7 8.4 8.3 8.6 6.3 6.5 10.8 9.5 0.3 13.2 5.6 5.4 5.4 4.4 8.0 16.1 11.6 15.8 7.8 7.2 9.7 12.0 13.4 10.6 14.9 6.9 12.6 16.6 27.5 31.5 11.0 17.8 5.3 17.0 8.7 37.3 22.9 11.6 12.0 2.1 9.5 10.1 23.3 21.1 18.8 11.6 7.6 3.5 7.3 15.0 17.5 5.2 6.7 10.0 1.6 13.0 10.9 15.1 15.4 6.0 16.6 15.1 7.0 6.3 16.4 22.2 0.0 11.3 8.3 15.1 20.3 18.9 5.0 9.2 11.1 EARS2 "KIAA1970, MSE1" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23522014-23557731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Erythroid cells: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043289, HPA043633" Approved Approved Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "HPA043289: AB_10963932, HPA043633: AB_10959901" "unprognostic (3.10e-2)" "unprognostic (1.60e-1)" "unprognostic (3.65e-3)" "unprognostic (4.20e-1)" "unprognostic (3.57e-1)" "unprognostic (4.64e-2)" "unprognostic (2.73e-1)" "unprognostic (2.91e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (8.09e-2)" "prognostic favorable (3.16e-6)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (4.29e-2)" 8.4 19.0 11.0 8.5 19.0 2.7 13.6 13.4 16.8 11.1 10.0 10.8 12.7 6.4 11.4 10.2 10.5 13.1 7.8 14.9 10.9 11.9 14.5 18.3 7.3 8.1 9.9 14.0 12.0 18.9 32.7 10.9 12.4 10.3 11.3 11.0 8.8 16.4 11.7 17.3 11.1 6.9 8.3 9.3 7.6 9.2 12.6 10.4 6.3 14.5 9.0 11.0 8.6 16.9 3.0 6.2 0.5 5.5 10.6 7.9 3.3 8.2 16.8 7.9 12.7 5.5 7.9 9.6 9.2 7.0 11.4 9.5 12.2 8.4 11.5 9.5 8.5 7.1 9.3 29.7 16.9 10.9 4.6 14.4 6.7 10.3 20.6 8.9 7.4 8.4 8.5 10.1 10.2 14.4 8.6 5.1 11.6 20.7 6.1 8.1 17.5 7.3 5.3 20.8 11.8 5.9 13.2 9.1 22.1 14.4 7.2 14.1 10.4 7.2 13.6 7.3 13.3 18.4 8.3 4.0 9.0 8.0 9.9 11.6 11.2 10.6 9.3 9.1 10.3 13.3 0.0 2.8 0.3 4.2 3.6 7.9 3.0 4.7 4.3 6.2 3.0 4.6 4.5 0.5 10.6 5.5 4.5 3.4 3.3 11.0 19.0 13.4 16.8 10.9 11.9 9.9 14.0 10.3 10.4 8.9 5.1 3.0 3.5 1.9 3.8 9.8 2.5 6.7 2.3 3.5 2.0 12.9 5.0 6.5 2.1 3.5 1.3 23.3 3.1 9.9 3.3 3.5 5.7 10.5 6.3 7.9 5.2 4.3 1.8 1.9 2.3 3.1 5.0 6.4 5.5 2.8 4.1 0.0 1.8 6.8 3.7 0.0 1.9 4.3 10.4 2.6 9.5 2.5 5.5 2.7 EPRS "EARS, GLUPRORS, PARS, QARS, QPRS" ENSG00000136628 "Glutamyl-prolyl-tRNA synthetase" P07814 1 219968601-220046658 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Aminoacyl-tRNA synthetase, Ligase, Multifunctional enzyme, RNA-binding" "Disease mutation, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026490, HPA030052" Enhanced Enhanced Cytosol NA NA 29000 Cytosol "HPA026490: AB_1855979, HPA030052: AB_10601466" "prognostic unfavorable (7.25e-4)" "unprognostic (1.19e-2)" "unprognostic (3.94e-2)" "unprognostic (2.60e-2)" "unprognostic (7.98e-3)" "unprognostic (1.12e-2)" "unprognostic (3.41e-3)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.30e-1)" "unprognostic (7.13e-2)" "unprognostic (5.12e-2)" "unprognostic (2.32e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.62e-4)" 25.0 20.4 16.8 18.6 22.2 13.2 20.6 24.2 26.3 19.3 20.4 15.4 13.6 15.8 17.8 15.3 25.2 15.9 11.9 20.1 15.9 18.0 23.3 31.6 17.4 20.8 21.7 16.1 21.3 32.7 47.1 38.6 15.7 34.9 14.3 23.2 9.4 64.0 16.3 42.9 19.6 23.3 18.9 24.7 22.3 20.1 13.2 20.8 28.0 25.1 25.7 23.4 18.3 16.3 14.7 15.4 6.4 16.6 14.2 19.8 10.7 30.1 19.2 13.9 38.0 29.6 32.9 34.9 39.5 27.7 25.7 28.9 22.7 24.4 57.9 22.0 41.6 10.4 32.3 34.9 31.8 34.6 28.3 22.2 31.5 25.9 19.4 32.4 52.2 27.0 23.7 40.9 32.8 41.1 21.5 28.1 28.0 54.1 45.7 25.1 14.9 22.4 12.7 26.9 35.7 39.8 23.8 24.6 56.6 23.5 13.3 33.1 26.0 23.1 38.3 40.3 20.8 35.4 57.1 24.9 12.3 22.7 37.6 36.7 31.0 35.2 49.0 28.3 37.6 38.8 4.2 11.9 6.4 14.0 16.6 19.8 14.7 14.1 15.6 15.4 11.5 15.9 16.3 0.4 14.2 13.7 5.0 13.5 10.7 16.8 22.2 24.2 26.3 15.9 18.0 21.7 16.1 34.9 20.8 65.5 52.5 37.9 33.6 17.6 45.2 67.4 15.3 69.6 69.4 29.6 62.8 36.3 18.3 58.3 19.1 33.8 24.4 23.3 87.1 48.7 27.0 24.9 47.4 18.8 38.0 39.7 29.4 22.1 23.8 7.4 43.7 27.7 20.3 53.3 32.2 45.5 61.8 14.4 44.6 21.4 47.0 38.8 27.8 57.6 34.9 17.8 30.6 29.8 41.8 29.3 FARS2 "dJ236A3.1, FARS1" ENSG00000145982 "Phenylalanyl-tRNA synthetase 2, mitochondrial" O95363 6 5261044-5771580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 61.5;Late spermatids: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018148, HPA028836" Approved NA NA "HPA018148: AB_1848426, HPA028836: AB_10601377" "unprognostic (2.73e-1)" "unprognostic (4.08e-3)" "prognostic favorable (5.14e-4)" "unprognostic (2.68e-1)" "unprognostic (1.94e-2)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (4.31e-3)" "unprognostic (7.18e-2)" "unprognostic (1.02e-2)" "unprognostic (8.91e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.81e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" 14.2 19.0 10.6 16.5 14.5 13.2 14.8 16.5 18.8 14.7 13.5 16.4 13.4 9.6 15.3 12.7 13.7 19.8 11.6 19.0 10.5 9.0 18.4 18.5 13.0 21.8 8.9 15.0 11.7 14.0 18.9 29.2 11.4 10.6 12.2 15.2 19.3 15.3 13.5 22.8 15.4 13.0 13.2 8.5 15.0 13.9 15.4 11.0 20.6 19.7 16.0 22.0 13.1 12.9 13.9 16.8 3.2 10.3 14.9 17.5 10.9 8.3 8.1 8.7 9.3 10.8 13.0 7.2 9.3 10.9 12.0 11.9 10.9 6.5 11.8 14.4 8.9 11.7 8.4 11.1 14.9 12.6 35.2 7.4 4.7 7.2 9.4 5.6 11.3 7.0 10.3 14.7 13.8 9.8 7.1 14.5 13.4 13.9 2.7 8.8 8.6 12.0 12.5 5.3 13.0 7.8 12.0 10.8 23.2 11.5 10.0 14.9 7.5 8.5 6.8 10.4 11.9 13.6 12.3 8.2 13.2 6.0 7.6 11.8 5.7 19.7 6.4 7.2 6.7 16.2 0.1 9.4 3.2 15.6 10.3 13.9 13.9 14.1 14.5 16.8 11.3 15.6 15.5 0.7 14.9 7.3 9.9 17.5 10.9 10.6 14.5 16.5 18.8 10.5 9.0 8.9 15.0 10.6 11.0 8.9 13.6 6.7 13.6 13.2 8.5 15.7 10.2 24.1 2.3 8.7 2.0 16.3 23.2 12.0 61.5 10.7 6.2 0.0 11.4 17.4 9.5 7.3 21.9 10.6 13.8 0.0 10.3 10.4 15.2 54.1 5.8 10.0 5.0 10.0 8.1 11.3 7.1 10.5 6.7 25.4 9.3 0.0 7.3 7.9 9.1 11.5 8.9 20.1 10.8 9.7 FARSA "CML33, FARSL, FARSLA" ENSG00000179115 "Phenylalanyl-tRNA synthetase alpha subunit" Q9Y285 19 12922479-12934037 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001911 Enhanced Approved Cytosol NA NA 11000 Cytosol "HPA001911: AB_1848427" "unprognostic (1.52e-1)" "prognostic favorable (8.23e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.22e-4)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (4.93e-3)" "unprognostic (5.76e-2)" "unprognostic (2.86e-1)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (1.45e-3)" "prognostic favorable (8.32e-4)" "unprognostic (2.59e-1)" "unprognostic (8.25e-2)" "unprognostic (1.84e-2)" 18.0 20.7 24.8 23.6 29.5 23.5 15.4 24.6 49.2 17.7 24.0 18.3 14.9 22.1 16.1 13.1 26.6 21.2 16.3 24.9 23.9 30.1 23.0 39.6 13.4 27.6 25.6 28.1 19.1 26.7 17.8 21.0 22.9 29.1 18.5 15.0 14.8 25.1 20.4 33.3 27.8 18.8 15.3 17.2 21.2 18.9 17.1 18.6 32.7 24.4 15.2 22.0 19.5 15.2 34.7 42.2 28.9 41.2 38.3 40.2 39.7 29.1 27.6 11.1 23.9 7.7 7.3 20.0 21.0 13.6 30.1 23.7 33.8 12.4 32.3 33.8 11.8 12.2 22.4 27.0 24.0 11.0 18.9 40.7 25.3 24.3 26.7 25.0 48.8 33.4 10.0 17.7 23.2 18.7 9.9 16.3 32.9 38.2 6.8 12.6 39.2 57.9 60.7 34.6 18.1 46.9 30.0 11.5 41.4 15.8 17.2 34.8 31.9 14.1 24.4 14.9 5.4 19.2 29.7 15.6 24.5 10.8 37.2 39.0 45.2 38.5 33.6 22.2 44.1 25.3 17.3 39.2 28.9 32.5 41.2 40.2 31.9 32.0 30.2 42.2 34.7 32.9 31.2 2.5 38.3 30.4 34.1 29.4 39.7 24.8 29.5 24.6 49.2 23.9 30.1 25.6 28.1 29.1 18.6 8.9 21.3 25.9 20.3 22.6 23.5 22.1 2.5 13.4 13.6 22.7 9.8 74.5 49.7 50.2 3.9 18.0 20.6 23.3 40.4 65.4 18.4 19.3 23.1 22.9 56.1 17.5 21.9 17.2 26.9 7.5 17.5 19.2 32.1 52.3 22.0 19.4 40.6 24.6 12.4 43.4 13.0 6.5 20.6 14.6 41.5 25.7 80.9 27.7 31.6 19.5 FARSB "FARSLB, FRSB, PheHB" ENSG00000116120 "Phenylalanyl-tRNA synthetase beta subunit" Q9NSD9 2 222570536-222656337 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036677, HPA036678, HPA061398" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA036677: AB_2675242, HPA036678: AB_10673504, HPA061398: AB_2684504" "unprognostic (9.95e-3)" "unprognostic (1.86e-3)" "unprognostic (7.02e-2)" "unprognostic (7.42e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.45e-10)" "unprognostic (8.89e-3)" "unprognostic (4.51e-2)" "unprognostic (3.63e-2)" "unprognostic (5.25e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.25e-4)" 15.7 10.8 11.9 12.6 23.5 11.5 16.0 15.1 28.5 11.6 17.3 13.7 5.9 15.9 14.2 11.7 19.1 10.8 7.2 13.4 13.7 15.1 11.7 18.3 9.0 12.0 11.6 18.0 16.7 18.6 15.0 15.7 8.8 29.4 11.2 20.7 9.6 12.3 11.5 33.2 14.1 11.5 14.9 9.7 10.3 13.9 15.6 11.2 15.6 11.9 17.1 14.2 11.8 12.0 16.3 16.0 1.2 11.4 18.5 20.0 14.6 22.2 13.1 15.3 20.0 14.0 20.1 23.6 22.7 14.4 22.5 18.4 33.2 12.3 10.9 17.3 16.6 18.7 18.8 29.4 25.5 33.1 16.3 15.2 25.1 14.8 21.1 21.8 36.5 10.4 13.4 20.0 25.6 39.4 8.0 21.2 19.3 37.7 22.6 27.3 20.8 21.8 20.7 19.5 26.9 16.4 21.5 36.8 35.4 18.4 14.6 24.8 8.1 9.5 16.7 19.6 19.5 15.5 15.4 11.5 19.3 15.9 27.6 27.4 10.8 10.8 39.9 15.0 24.6 20.1 0.2 8.5 1.2 11.4 10.3 16.8 16.3 15.4 14.0 16.0 14.0 20.0 17.2 0.9 18.5 11.4 8.0 13.3 14.6 11.9 23.5 15.1 28.5 13.7 15.1 11.6 18.0 29.4 11.2 6.0 5.4 20.0 16.1 11.0 15.1 26.0 2.5 16.0 10.3 21.0 3.9 30.6 29.9 19.9 43.7 9.9 12.3 0.0 26.1 35.9 12.8 11.4 4.7 16.2 24.6 3.2 20.1 7.4 9.7 57.3 14.1 10.8 6.8 9.0 19.0 9.8 18.6 7.0 18.7 20.7 17.1 6.5 16.5 59.3 37.3 12.4 18.5 13.3 40.3 12.0 FPGS ENSG00000136877 "Folylpolyglutamate synthase" Q05932 9 127794597-127814327 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050488 Approved "Intracellular and membrane" NA NA "HPA050488: AB_2681143" "unprognostic (6.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (6.97e-2)" "unprognostic (1.76e-1)" "unprognostic (8.54e-3)" "unprognostic (2.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" 18.2 25.0 6.0 17.4 7.1 14.8 18.9 7.9 6.9 13.9 16.6 9.2 16.6 9.3 16.8 19.2 12.2 17.1 20.0 19.2 6.1 5.9 12.5 44.0 14.9 25.6 8.1 6.6 41.3 24.0 6.6 8.9 6.7 7.7 12.8 6.3 9.9 12.3 18.9 30.4 7.9 10.3 12.6 5.4 17.6 12.4 10.1 7.7 13.6 11.1 15.2 16.0 14.7 9.2 15.5 19.9 1.0 11.8 20.4 21.1 10.2 13.6 9.5 5.4 11.7 8.5 9.3 16.9 10.9 12.9 13.9 10.6 9.8 22.3 17.0 14.2 14.7 9.3 25.8 6.7 14.8 4.5 18.5 8.8 13.2 11.9 12.0 20.3 24.3 11.3 13.0 8.5 13.2 17.7 11.7 16.5 16.0 14.8 11.0 14.2 17.3 21.1 18.1 15.8 15.0 29.1 44.0 9.1 29.5 20.0 11.0 8.2 14.0 31.3 15.3 2.1 2.3 9.2 10.3 24.9 7.2 10.3 20.9 21.6 12.3 5.2 13.6 15.7 11.3 10.5 0.1 7.8 1.0 21.1 11.8 18.9 12.2 12.6 18.2 15.6 15.5 10.4 13.7 0.4 20.4 11.6 19.9 13.1 10.2 6.0 7.1 7.9 6.9 6.1 5.9 8.1 6.6 7.7 7.7 20.8 29.1 20.1 17.5 9.3 5.4 18.0 33.1 6.7 19.4 8.7 13.7 13.4 10.0 43.0 3.1 16.3 13.6 0.0 46.4 18.3 16.9 18.0 30.1 61.4 27.0 4.8 22.0 16.5 12.7 2.1 17.5 18.2 8.5 71.3 10.9 6.3 54.2 10.5 6.7 15.9 6.5 12.9 16.5 6.5 16.6 7.8 12.4 22.3 22.2 28.6 GARS "CMT2D, DSMAV, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase" P41250 7 30594681-30634033 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 660000 Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavorable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.04e-5)" 25.8 27.3 24.5 26.2 28.5 24.6 32.4 31.1 44.7 21.5 23.7 17.0 11.5 17.2 24.1 23.3 43.7 18.6 18.4 25.7 21.1 26.8 27.6 57.2 27.9 28.0 22.9 28.4 35.4 49.4 44.4 33.3 24.3 37.6 17.2 30.2 14.1 28.7 21.6 35.6 33.2 18.1 30.1 17.6 23.5 30.5 29.7 14.9 28.6 31.4 33.9 38.4 22.8 25.7 22.5 26.4 21.2 27.2 15.3 27.6 21.2 33.5 16.6 14.8 52.3 27.6 41.5 28.0 50.2 45.5 25.9 52.5 22.1 16.8 56.5 15.2 61.1 40.7 26.6 36.8 31.9 45.6 13.5 17.2 26.1 13.6 18.6 87.7 38.4 23.1 39.5 56.0 37.1 44.1 18.4 33.2 52.5 51.7 65.9 41.1 20.7 33.4 26.6 39.8 31.0 31.8 16.9 13.0 43.9 29.7 15.2 17.8 29.9 13.4 37.6 71.4 27.6 33.5 58.9 30.4 12.3 41.3 24.7 31.7 65.2 54.6 66.5 43.0 58.2 57.8 21.2 19.0 17.7 23.2 25.8 23.7 22.5 23.7 25.1 26.4 19.3 25.5 27.6 5.6 15.3 27.2 18.0 25.9 21.2 24.5 28.5 31.1 44.7 21.1 26.8 22.9 28.4 37.6 14.9 38.7 27.4 35.6 34.3 29.9 23.3 30.7 25.5 14.7 27.3 19.2 21.6 41.1 28.2 79.9 48.1 24.6 13.9 0.0 131.2 61.8 33.2 32.2 40.3 27.0 39.9 17.5 25.2 31.9 25.5 44.0 21.6 32.4 32.1 57.7 36.9 20.2 111.3 7.0 21.5 31.8 15.7 12.9 30.0 71.9 80.1 24.1 33.3 25.4 22.3 44.7 GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002119, HPA005779" Approved Approved Mitochondria,Cytosol NA NA 1300000 Cytosol Mitochondria "HPA002119: AB_1849482, HPA005779: AB_1849484" "unprognostic (3.77e-2)" "unprognostic (2.25e-2)" "unprognostic (4.51e-3)" "unprognostic (1.72e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (5.05e-5)" "prognostic unfavorable (9.82e-5)" "unprognostic (2.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.92e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.98e-3)" "prognostic unfavorable (3.95e-6)" "unprognostic (1.36e-2)" "unprognostic (2.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" 24.9 24.7 16.0 20.0 22.3 14.2 22.2 14.5 20.3 16.2 20.1 20.5 13.3 18.9 21.7 15.9 28.1 19.9 14.3 19.3 16.4 14.9 19.2 33.6 18.3 24.4 21.9 14.6 21.0 30.6 21.6 22.9 23.1 21.0 16.4 26.9 19.5 18.6 16.1 33.2 17.6 19.1 23.5 17.9 21.4 21.9 47.0 21.7 40.8 20.0 19.4 32.8 21.6 17.6 18.7 19.5 9.7 20.9 27.1 21.1 13.3 30.2 14.4 21.3 23.6 15.7 16.2 24.0 19.6 16.7 23.0 24.4 27.3 25.7 40.3 11.7 13.1 30.1 16.0 44.7 30.8 33.6 21.1 26.6 60.8 17.2 17.8 21.5 33.7 16.0 14.3 21.6 27.1 39.9 11.7 21.7 32.6 70.6 25.9 20.7 14.5 35.6 22.6 46.6 44.2 17.0 29.7 39.8 57.0 18.4 16.2 22.7 20.5 27.2 21.4 25.4 20.6 27.2 21.7 15.9 15.6 18.7 13.5 21.0 25.8 35.6 44.0 16.4 39.7 23.1 5.3 15.2 9.7 17.3 20.9 21.1 18.7 16.9 17.9 19.5 14.4 17.7 17.4 7.0 27.1 17.7 14.7 20.6 13.3 16.0 22.3 14.5 20.3 16.4 14.9 21.9 14.6 21.0 21.7 17.9 17.5 28.9 32.0 40.9 17.7 16.9 2.5 14.7 26.1 14.0 33.4 35.3 19.9 22.6 9.1 20.1 11.8 0.0 20.8 29.3 16.6 18.9 7.0 17.1 21.0 4.8 12.6 16.5 18.7 2.2 16.1 16.9 11.8 17.2 15.1 12.9 24.5 10.5 17.0 11.3 25.4 12.9 25.0 50.8 27.2 40.1 21.4 17.5 20.8 38.9 GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in many" 9 "Hepatocytes: 102.4;Intestinal endocrine cells: 212.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 8.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 49.2;Hep G2: 42.0;OE19: 68.1;RT4: 45.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 3600000 Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favorable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.30e-2)" 15.8 11.1 12.9 9.0 16.0 14.4 13.0 5.4 15.1 6.8 16.2 21.6 8.2 18.9 9.2 5.3 20.0 29.1 14.9 7.4 13.1 10.6 15.4 69.2 12.9 10.1 21.6 12.2 6.2 12.4 6.6 5.4 6.2 13.0 13.0 12.2 5.2 11.2 10.1 7.0 8.6 14.8 11.9 13.6 16.8 14.8 5.2 17.5 3.1 14.1 32.4 10.6 34.4 12.3 1.6 4.2 2.2 1.9 8.0 2.3 0.6 7.3 49.2 4.0 9.5 4.8 2.2 5.4 3.7 6.0 2.8 3.3 7.2 17.1 14.0 7.1 3.3 21.5 10.5 12.3 27.1 3.8 11.0 7.6 9.3 9.5 42.0 5.5 12.3 5.8 3.4 11.5 3.1 14.1 3.7 4.2 12.3 5.1 4.4 1.3 7.7 10.5 4.9 7.5 68.1 4.6 3.5 2.5 12.3 9.1 45.4 11.7 5.7 6.2 10.0 6.5 6.1 6.8 5.8 5.9 2.5 8.8 6.4 5.5 5.9 9.1 8.1 6.3 8.8 4.2 2.2 1.1 0.6 1.2 1.9 0.8 1.6 1.0 2.3 4.2 1.0 0.6 1.3 0.5 8.0 1.8 3.0 1.6 0.6 12.9 16.0 5.4 11.9 13.1 10.6 21.6 12.2 13.0 17.5 0.0 3.7 7.8 42.9 30.9 12.8 17.8 25.5 48.2 47.8 0.0 23.6 5.2 10.0 12.8 1.4 13.5 19.9 46.7 11.0 6.5 8.7 44.8 2.3 102.4 19.8 7.9 212.1 9.2 60.1 1.0 6.1 16.4 8.5 6.4 16.3 13.8 17.1 8.5 8.9 19.8 4.0 12.9 10.3 3.3 8.1 21.8 6.5 10.7 13.8 89.1 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182381704-182392206 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Late spermatids: 6809.8;Muller glia cells: 5699.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 92.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 92.2" "Cell line enhanced" "Detected in many" "ASC diff: 141.5;ASC TERT1: 100.1;HSkMC: 86.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 28000 "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 173.3 19.2 83.7 37.2 91.0 47.6 63.1 48.5 80.7 41.9 20.4 49.9 9.4 6.2 20.5 29.7 54.0 31.6 26.2 23.5 74.0 48.7 15.6 64.9 39.5 36.9 71.0 48.8 66.2 49.0 7.4 8.9 41.8 70.6 17.4 23.3 39.3 30.4 25.5 159.8 27.9 16.4 30.5 51.3 36.1 71.4 24.0 55.2 8.6 63.9 15.5 24.2 34.7 32.2 2.5 11.0 92.2 21.1 3.4 6.3 18.6 3.0 1.2 14.0 0.0 141.5 100.1 10.3 5.1 16.6 3.1 2.8 7.4 3.1 2.6 5.6 9.9 2.8 7.0 6.1 36.4 2.6 7.0 17.0 34.3 5.8 14.3 7.5 15.1 27.4 86.5 43.7 3.9 46.4 4.7 6.2 8.4 28.8 1.5 11.0 1.7 23.5 14.5 10.4 4.2 6.5 8.5 3.7 4.4 5.4 13.3 9.6 6.3 1.4 18.7 2.0 11.7 18.2 19.1 4.6 0.1 0.2 0.0 1.1 0.5 0.3 0.0 2.7 8.6 0.5 43.6 21.1 54.9 6.3 20.5 2.6 1.6 4.5 5.2 11.0 2.5 2.3 3.9 92.2 3.4 17.1 6.1 1.7 18.6 83.7 91.0 48.5 80.7 74.0 48.7 71.0 48.8 70.6 55.2 116.1 193.4 39.3 480.1 119.7 83.9 198.1 163.1 242.2 133.1 78.5 49.1 126.6 63.0 92.2 1437.2 175.0 45.7 210.2 99.7 54.7 230.2 354.1 758.5 179.4 734.4 41.3 312.5 129.5 692.2 6809.8 451.3 662.6 129.9 48.7 226.1 5699.1 116.5 83.4 352.5 40.4 128.3 90.5 209.3 38.8 52.4 112.0 196.8 96.9 130.8 1061.5 GMPS GATD7 ENSG00000163655 "Guanine monophosphate synthase" P49915 3 155870536-155944026 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" Ligase Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Early spermatids: 191.9;Late spermatids: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046630 Approved Cytosol No No Cytosol "HPA046630: AB_2679727" "unprognostic (3.89e-2)" "unprognostic (2.02e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (5.54e-5)" "unprognostic (2.30e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (8.73e-7)" "unprognostic (1.71e-2)" "unprognostic (3.52e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.58e-2)" "unprognostic (2.79e-2)" "unprognostic (2.89e-2)" "unprognostic (3.78e-1)" "unprognostic (3.55e-3)" "unprognostic (8.79e-2)" 15.9 18.3 10.4 19.7 14.0 24.6 22.4 22.1 24.9 16.1 13.9 9.8 15.3 10.3 17.5 15.4 19.5 14.0 10.8 15.3 9.2 7.7 11.0 14.7 15.8 19.5 9.3 12.1 15.7 23.5 19.1 14.1 13.5 14.8 13.0 15.3 9.0 21.6 18.6 16.6 21.0 12.6 16.1 8.9 14.6 15.4 60.9 10.5 28.3 13.6 12.5 18.4 15.9 18.5 11.1 17.2 10.9 18.1 19.0 20.7 10.8 56.8 22.5 30.6 25.0 12.5 19.8 29.5 24.3 22.5 32.1 32.5 41.0 38.4 41.1 29.0 18.7 24.6 28.0 26.0 25.5 44.2 23.8 20.0 43.8 16.5 22.2 14.3 44.5 17.1 14.6 15.7 24.8 38.0 17.1 19.6 22.4 30.8 15.8 23.8 38.2 36.1 23.6 29.3 31.3 16.7 35.5 36.3 49.6 16.5 25.1 18.3 17.0 27.0 38.7 24.2 22.0 40.5 29.4 13.8 21.3 17.3 30.0 48.9 22.1 13.6 70.3 21.4 33.2 18.9 10.9 10.4 7.2 17.3 13.1 20.7 11.1 16.8 15.7 17.2 8.8 16.8 15.8 1.4 19.0 18.1 9.5 17.6 10.8 10.4 14.0 22.1 24.9 9.2 7.7 9.3 12.1 14.8 10.5 17.9 19.8 20.4 39.9 35.4 21.9 14.1 15.3 13.4 22.7 7.0 2.0 33.4 21.6 24.9 191.9 28.5 8.4 23.3 25.9 43.0 27.2 23.6 28.8 11.1 26.5 20.6 6.9 14.7 18.3 149.6 21.3 24.7 21.9 29.7 17.8 17.3 20.4 10.5 23.3 22.3 7.7 19.4 31.6 80.1 54.5 33.4 25.7 24.9 24.7 34.5 GSS ENSG00000100983 "Glutathione synthetase" P48637 20 34928433-34956027 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease mutation, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054508, HPA059315" Enhanced Supported Nucleoplasm NA NA 23000000 Nucleoplasm "HPA054508: AB_2682509, HPA059315: AB_2683976" "unprognostic (5.80e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (7.21e-2)" "unprognostic (3.63e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (7.21e-5)" "unprognostic (2.90e-2)" "unprognostic (8.52e-2)" "unprognostic (3.64e-1)" "unprognostic (6.49e-2)" "unprognostic (1.50e-1)" "prognostic favorable (7.31e-6)" "unprognostic (3.35e-3)" "unprognostic (1.96e-1)" "unprognostic (1.42e-3)" "unprognostic (1.52e-1)" 12.9 29.8 14.7 13.2 21.0 16.0 16.2 9.2 27.6 12.7 26.9 17.2 28.9 20.0 11.5 47.5 25.6 18.5 18.3 14.6 15.0 15.9 30.5 30.9 12.1 11.7 15.1 15.1 11.6 10.3 17.5 15.6 27.2 15.3 18.6 27.6 15.4 19.1 19.4 10.7 19.1 21.4 12.9 13.3 13.3 15.7 16.8 9.2 17.0 18.0 12.0 21.0 14.4 13.9 7.3 24.3 7.9 21.3 15.2 18.3 14.9 18.2 22.2 10.9 15.3 12.7 13.2 15.5 15.6 14.4 24.6 20.4 40.7 22.3 12.9 20.8 16.0 23.8 17.4 15.9 39.7 20.8 6.0 9.0 51.0 14.1 40.4 17.9 12.8 18.0 13.9 42.5 23.1 39.1 11.0 17.4 17.6 24.6 10.6 29.8 20.1 20.4 18.2 6.4 24.1 28.7 18.8 21.9 30.7 35.2 18.7 21.4 12.5 27.5 25.8 20.5 6.2 31.7 11.7 13.7 28.3 16.1 18.6 13.4 10.8 10.0 14.2 24.1 14.1 16.8 7.9 20.3 4.6 18.0 21.3 16.1 7.3 14.5 18.3 24.3 5.2 16.9 14.3 5.3 15.2 19.0 13.5 17.5 14.9 14.7 21.0 9.2 27.6 15.0 15.9 15.1 15.1 15.3 9.2 17.9 8.0 10.4 28.7 23.4 20.6 14.0 30.6 8.1 12.5 24.4 9.8 69.5 21.6 40.0 44.5 14.6 44.5 0.0 41.7 42.0 15.3 18.9 17.3 23.3 52.3 33.4 22.5 5.5 16.2 108.3 9.5 20.4 15.1 40.5 44.4 26.6 32.4 28.8 17.3 95.3 15.4 25.8 12.2 16.4 14.7 21.1 41.0 20.3 70.9 22.9 HARS USH3B ENSG00000170445 "Histidyl-tRNA synthetase" P12081 5 140673904-140691862 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Charcot-Marie-Tooth disease, Deafness, Disease mutation, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036539 Approved Enhanced Cytosol NA NA 52000 Cytosol "HPA036539: AB_10669796" "unprognostic (9.35e-2)" "unprognostic (9.95e-2)" "unprognostic (1.62e-3)" "unprognostic (1.65e-2)" "unprognostic (2.33e-1)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.50e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.36e-1)" 22.4 24.5 28.5 21.1 35.5 18.1 21.0 41.1 46.3 20.6 22.7 20.0 23.6 17.4 21.6 23.5 26.9 23.7 17.5 25.1 29.5 35.9 20.6 34.2 16.7 22.4 36.9 33.0 24.7 25.2 29.5 38.7 15.0 38.2 21.7 24.8 13.6 22.1 27.9 27.1 33.9 16.4 28.0 21.0 18.3 18.8 16.6 23.5 17.6 19.4 20.3 28.5 19.9 20.9 16.8 22.1 10.7 22.9 25.2 29.4 23.4 20.6 30.2 18.2 39.7 23.2 25.3 19.2 33.3 24.0 38.5 36.0 54.9 17.5 27.5 29.3 37.3 31.1 21.7 27.6 53.5 36.3 23.3 34.1 19.8 39.2 34.8 28.8 31.1 17.0 26.7 16.8 41.9 23.9 23.0 38.6 17.1 17.3 22.9 40.0 35.5 22.1 29.0 14.3 16.7 19.9 20.5 26.4 22.4 30.9 26.4 28.6 27.7 27.6 40.2 26.2 18.3 29.6 17.5 32.2 36.1 13.9 20.3 44.8 23.1 27.4 27.8 27.4 26.1 24.7 6.7 14.1 10.7 29.4 20.8 26.3 16.8 25.8 27.3 22.1 14.8 28.2 26.9 4.3 25.2 22.9 15.6 22.1 23.4 28.5 35.5 41.1 46.3 29.5 35.9 36.9 33.0 38.2 23.5 14.9 19.4 29.8 29.5 27.2 27.3 7.7 20.4 14.7 15.9 26.2 13.7 35.0 38.1 46.0 30.2 30.6 23.2 0.0 37.0 41.1 27.2 20.1 15.1 76.4 31.4 28.6 24.8 26.4 17.5 15.9 23.3 22.3 35.4 61.3 22.2 20.7 37.7 23.0 32.5 33.8 20.0 45.3 41.8 29.6 30.4 28.4 30.1 30.2 25.5 25.7 HARS2 "HARSL, HARSR, HO3" ENSG00000112855 "Histidyl-tRNA synthetase 2, mitochondrial" P49590 5 140691426-140699318 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035941 Approved Approved Cytosol "Intracellular and membrane" NA NA Cytosol "HPA035941: AB_10671237" "prognostic unfavorable (6.49e-4)" "unprognostic (3.15e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.79e-2)" "unprognostic (1.78e-1)" "unprognostic (8.30e-3)" "prognostic unfavorable (2.92e-4)" "unprognostic (7.77e-2)" "unprognostic (1.88e-1)" "unprognostic (5.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.68e-2)" "unprognostic (1.85e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (1.31e-2)" 17.1 23.8 14.2 22.9 19.4 13.4 25.0 24.7 19.0 15.0 21.6 16.6 19.7 17.7 20.2 16.9 16.7 14.9 16.7 25.2 15.7 12.6 19.6 14.5 21.4 25.2 15.5 11.2 17.4 13.6 22.9 21.1 15.8 14.4 14.3 24.4 16.4 16.4 15.4 32.7 18.3 17.2 15.6 12.9 18.5 17.9 15.1 15.6 16.5 15.8 13.9 18.8 20.6 18.4 13.7 12.0 22.9 15.0 22.8 17.6 9.7 10.9 24.7 10.7 27.5 12.2 16.2 17.7 14.1 16.1 19.9 17.4 22.6 13.8 13.9 22.8 15.6 19.6 13.9 14.8 26.5 18.4 13.9 12.2 10.1 23.7 14.9 11.8 13.5 14.9 15.2 18.1 19.4 22.0 16.1 14.3 14.7 9.3 13.1 19.2 13.9 13.2 16.8 12.3 8.3 15.6 13.5 10.9 14.0 18.6 25.6 14.9 21.4 20.5 33.3 27.9 16.3 29.4 13.5 17.4 17.9 9.9 9.9 18.6 13.0 18.9 13.4 14.1 15.6 17.8 22.9 10.5 21.3 16.2 15.0 17.5 13.7 15.6 16.2 12.0 12.5 16.4 17.6 12.1 22.8 11.4 9.5 15.3 9.7 14.2 19.4 24.7 19.0 15.7 12.6 15.5 11.2 14.4 15.6 3.0 4.3 10.4 3.8 3.1 4.8 16.5 2.5 9.4 6.8 5.2 0.0 16.4 11.6 11.9 0.9 7.1 6.7 0.0 14.0 15.3 6.3 3.7 2.3 5.9 8.8 0.0 7.5 6.7 7.8 1.7 8.6 8.3 3.3 12.6 7.2 7.7 13.2 10.5 9.9 6.7 5.2 0.0 7.2 6.4 14.1 3.4 12.0 7.5 11.2 3.9 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36750888-36990236 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA Cytosol "HPA017379: AB_1850768" "prognostic unfavorable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 6.3 9.6 7.1 9.8 10.3 2.9 10.6 12.2 8.5 7.7 7.2 10.3 12.1 5.7 6.4 9.4 7.1 8.1 9.9 5.3 8.4 8.0 9.1 16.4 6.7 5.8 10.2 6.0 5.5 15.6 23.3 23.9 9.9 9.4 12.8 6.4 11.7 9.9 11.6 13.5 4.3 8.1 7.3 10.6 4.5 7.6 7.7 5.1 4.9 14.3 6.1 8.0 9.2 4.9 3.9 5.3 3.2 10.0 8.5 7.8 2.9 18.0 6.7 10.1 7.3 12.1 11.0 9.9 11.0 10.6 5.0 5.6 7.2 8.5 9.8 5.3 15.9 10.4 6.2 5.1 8.4 4.5 19.5 10.5 14.5 6.6 4.6 14.4 7.8 7.5 8.7 13.0 7.6 20.3 9.6 6.3 9.6 15.6 25.1 12.7 10.9 3.5 3.6 15.8 12.4 9.4 6.1 5.8 7.9 7.8 18.2 7.1 7.4 14.5 6.7 11.1 8.3 11.8 8.0 8.5 7.3 2.2 6.6 6.0 24.3 14.9 6.1 10.5 9.8 8.4 3.2 2.1 1.6 7.8 4.0 6.1 2.6 4.5 5.2 2.0 3.9 5.4 5.5 2.7 8.5 10.0 5.3 2.7 2.9 7.1 10.3 12.2 8.5 8.4 8.0 10.2 6.0 9.4 5.1 8.9 12.2 0.5 8.0 3.0 12.5 3.2 15.3 6.7 9.1 12.2 21.6 6.8 6.6 6.7 4.4 2.2 4.0 0.0 6.9 4.9 3.0 9.1 5.7 14.9 3.9 17.5 5.8 4.3 3.1 2.9 4.0 3.4 0.0 3.6 6.5 6.3 7.2 2.9 6.7 5.6 13.6 0.0 6.4 4.4 8.7 3.4 4.2 2.5 5.2 5.4 IARS "IARS1, ILRS" ENSG00000196305 "Isoleucyl-tRNA synthetase" P41252 9 92210207-92293756 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029806 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA029806: AB_10601818" "unprognostic (1.32e-3)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (8.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.98e-7)" "unprognostic (2.00e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (4.96e-2)" "unprognostic (3.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.88e-2)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (7.76e-3)" 20.6 31.0 19.1 21.1 28.5 13.8 24.8 24.5 32.1 22.8 23.7 17.5 25.8 13.6 31.9 24.8 29.7 23.8 15.1 26.0 21.4 18.5 24.5 29.9 24.4 24.1 21.6 20.6 28.4 42.8 57.4 29.0 21.1 31.6 23.6 26.7 17.1 25.2 27.7 47.4 25.4 18.8 32.6 20.0 23.1 29.0 18.7 16.9 25.1 52.3 26.7 28.8 22.1 20.5 14.5 15.3 1.9 7.3 18.6 18.6 9.7 35.0 36.3 20.3 32.0 33.5 37.8 32.2 37.2 35.5 29.5 36.1 12.7 22.6 47.6 14.7 57.4 32.5 43.9 62.6 48.4 37.3 29.9 23.3 29.0 31.3 22.6 70.8 39.5 21.5 36.8 54.4 51.4 85.1 19.4 31.0 57.2 51.1 43.3 41.4 25.5 36.5 15.4 32.9 74.5 33.6 25.6 30.9 22.9 24.3 17.6 26.0 21.6 25.2 27.7 35.0 22.9 22.2 24.8 22.8 21.8 27.3 36.0 30.2 31.7 40.5 25.2 51.0 30.5 40.2 1.9 6.7 0.5 14.7 7.3 18.6 14.5 14.5 14.9 15.3 10.7 14.7 15.3 0.8 18.6 6.2 6.2 12.9 9.7 19.1 28.5 24.5 32.1 21.4 18.5 21.6 20.6 31.6 16.9 17.9 25.5 29.7 27.4 60.8 34.2 44.5 40.8 24.1 27.3 17.4 43.2 23.5 13.3 22.2 8.9 20.8 5.4 0.0 25.9 26.2 31.1 25.2 36.9 26.0 15.7 9.5 11.5 16.0 21.6 4.0 26.4 17.7 13.5 11.8 23.8 15.5 26.0 8.6 27.6 29.1 34.6 6.5 32.5 39.2 38.1 59.2 14.5 18.7 26.3 27.4 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094102-220148041 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease mutation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 26000 Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 25.9 39.3 18.0 17.9 16.9 6.7 31.9 15.1 20.8 16.9 26.2 14.8 24.3 18.9 21.5 16.8 23.8 18.8 16.5 40.0 17.5 12.6 29.5 37.3 16.8 25.9 15.6 16.0 20.5 20.5 42.5 15.3 26.2 17.4 18.5 24.9 15.0 22.4 22.3 57.8 22.2 23.4 17.7 15.7 16.1 18.5 15.7 13.7 19.5 17.8 25.9 20.1 24.9 18.7 16.8 20.0 17.2 19.0 18.5 22.6 16.8 38.3 36.0 20.7 20.3 31.3 31.6 49.9 23.4 25.2 25.9 21.0 34.6 40.1 35.5 31.7 28.9 20.1 37.3 28.7 29.2 30.0 24.5 34.6 17.6 29.4 38.8 19.5 27.9 19.1 22.8 29.8 28.0 29.0 25.1 25.2 23.1 43.4 20.6 33.9 21.3 22.0 20.2 26.9 30.0 23.9 19.5 41.3 56.8 37.3 25.8 11.2 31.5 35.4 55.0 36.4 24.8 63.6 31.7 25.7 25.6 21.4 34.3 39.1 17.7 27.1 25.8 27.1 22.0 28.3 17.2 16.7 15.1 16.8 19.0 22.6 16.8 18.4 22.0 20.0 13.6 20.8 19.0 3.3 18.5 14.5 7.3 19.7 16.8 18.0 16.9 15.1 20.8 17.5 12.6 15.6 16.0 17.4 13.7 32.8 33.1 24.4 24.3 17.9 26.7 126.1 15.3 58.9 45.5 27.9 23.6 68.4 10.0 37.8 12.3 43.0 33.8 0.0 56.4 44.9 24.9 20.4 18.5 88.4 40.3 19.1 34.8 38.6 46.6 2.0 34.5 26.7 18.6 25.2 50.3 28.6 54.2 28.8 40.0 28.3 31.0 45.3 22.6 32.5 40.2 23.2 60.0 22.7 61.0 20.5 KARS "DFNB89, KARS1, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease mutation, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA Cytosol "Plasma membrane" "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" 25.4 21.1 19.2 29.2 22.0 24.6 28.0 17.5 19.5 26.3 28.3 15.2 28.1 20.6 23.4 26.7 35.8 24.1 27.5 49.6 16.3 18.6 31.7 47.1 25.8 26.6 18.8 16.2 34.9 62.6 28.5 22.4 30.4 19.6 30.7 29.7 20.1 31.7 23.2 80.0 26.6 32.3 28.4 17.1 37.3 26.3 33.6 14.5 41.3 34.4 43.6 34.7 38.6 33.4 32.8 39.0 35.5 44.2 35.0 62.4 39.5 27.2 31.9 23.3 32.0 25.0 25.3 45.9 23.1 28.4 50.9 38.4 56.3 35.9 49.2 25.6 30.7 24.3 39.3 46.9 42.2 55.7 14.3 24.1 27.0 27.9 58.2 45.9 40.6 30.5 29.7 30.4 45.0 73.3 26.0 41.4 43.5 45.0 11.8 38.4 63.0 41.7 43.5 49.3 40.1 23.5 55.0 20.9 60.0 40.8 23.2 35.1 28.5 58.1 21.2 25.8 26.6 28.7 38.5 22.8 28.2 29.1 21.5 33.0 25.4 29.0 117.4 24.6 34.8 34.3 20.9 31.5 35.5 34.1 44.2 62.4 32.8 42.3 40.2 39.0 27.6 40.1 36.1 7.2 35.0 43.2 24.6 43.5 39.5 19.2 22.0 17.5 19.5 16.3 18.6 18.8 16.2 19.6 14.5 41.7 22.7 66.3 80.5 40.9 19.6 83.2 53.5 42.8 59.1 38.4 33.4 104.3 89.5 100.0 165.6 61.2 50.2 46.7 126.0 122.6 54.5 53.6 38.2 37.5 80.9 11.1 54.8 39.3 59.8 236.5 43.4 52.9 33.7 143.3 61.7 20.0 101.6 42.1 47.7 58.7 38.2 45.3 49.9 89.9 114.1 39.5 92.0 63.4 85.8 94.5 LARS "FLJ10595, FLJ21788, HSPC192, LARS1, LEUS, RNTLS" ENSG00000133706 "Leucyl-tRNA synthetase" Q9P2J5 5 146113038-146182660 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036424, HPA040881" Supported Approved "Nuclear bodies,Cytosol" NA NA 14000 "Nuclear bodies, Cytosol" "HPA036424: AB_10670102, HPA040881: AB_2677185" "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-3)" "unprognostic (1.92e-1)" "unprognostic (2.69e-1)" "unprognostic (3.39e-1)" "prognostic unfavorable (3.78e-5)" "unprognostic (8.17e-2)" "unprognostic (2.72e-1)" "unprognostic (6.80e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.96e-2)" 32.2 30.1 27.0 25.8 31.2 17.8 38.6 31.8 33.7 25.5 25.3 30.1 23.9 16.8 35.8 31.3 28.5 26.8 16.4 29.0 24.2 22.2 26.5 18.4 20.0 24.8 27.3 26.1 32.0 40.8 35.0 43.0 20.6 31.6 26.3 29.9 19.5 39.9 24.8 55.5 24.1 21.5 32.5 30.9 25.2 24.9 20.5 30.5 25.6 30.8 22.8 28.9 30.9 29.2 21.3 28.0 5.8 18.3 19.0 21.8 11.2 20.5 24.3 28.2 46.2 23.4 30.5 43.9 24.1 17.8 24.4 35.3 25.4 22.5 31.3 14.9 31.6 30.9 17.6 47.6 39.6 42.7 26.9 28.0 35.7 30.8 14.7 32.4 50.7 23.7 23.9 39.9 39.9 69.3 22.0 33.2 46.5 39.7 58.7 26.1 17.0 39.1 31.1 43.7 16.6 27.0 30.3 35.5 31.2 18.6 18.6 27.8 35.1 26.2 28.9 60.8 28.0 32.8 43.8 32.5 28.5 19.0 25.8 36.0 30.5 45.0 51.2 31.0 53.6 33.2 2.5 13.5 5.8 14.8 18.3 19.8 21.1 16.4 13.6 18.6 21.3 21.8 18.0 1.2 19.0 13.6 28.0 14.8 11.2 27.0 31.2 31.8 33.7 24.2 22.2 27.3 26.1 31.6 30.5 26.8 57.1 43.4 48.5 24.6 46.8 120.8 22.9 81.7 77.3 45.4 39.3 32.4 43.1 59.7 27.5 55.0 26.5 0.0 47.0 33.7 27.8 49.5 77.6 28.0 32.9 20.6 30.6 29.4 40.0 22.8 58.1 39.7 21.9 59.5 33.8 40.2 49.7 28.1 56.6 52.5 48.0 32.3 59.7 106.6 46.2 31.0 27.6 32.0 43.8 38.2 LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388506-45549421 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035951, HPA045450, HPA066085" Approved Supported Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "HPA035951: AB_10672997, HPA045450: AB_2679328, HPA066085: AB_2685612" "unprognostic (3.89e-1)" "unprognostic (3.89e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.02e-2)" "unprognostic (3.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (9.19e-2)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-1)" "unprognostic (4.37e-2)" "prognostic favorable (1.32e-11)" "unprognostic (2.81e-1)" "unprognostic (5.74e-2)" "unprognostic (9.90e-2)" "unprognostic (9.07e-2)" 9.6 14.3 18.8 9.6 21.8 6.7 8.1 11.9 17.9 9.2 14.8 13.1 8.3 9.6 9.8 8.9 10.4 11.2 8.4 14.2 14.6 13.6 18.9 17.2 7.0 10.3 15.7 9.5 10.2 8.2 20.0 14.0 10.6 12.3 10.8 15.3 10.0 8.7 9.8 14.1 7.8 8.8 11.0 8.8 10.0 8.9 7.3 11.8 16.1 10.5 8.3 12.8 11.3 7.8 5.1 5.9 2.4 3.3 8.4 6.0 3.7 6.4 8.0 9.4 8.9 8.6 9.7 10.1 10.0 10.3 18.7 13.9 14.2 8.9 13.3 8.6 11.6 13.7 7.0 34.9 20.9 14.2 11.6 8.8 14.4 13.0 13.8 9.0 20.8 5.3 12.5 12.9 17.8 9.4 9.7 11.6 16.1 22.3 7.5 11.6 7.0 14.9 7.6 23.5 10.8 14.9 8.5 9.3 14.8 16.6 15.5 7.4 9.3 15.9 9.0 8.3 11.2 14.3 12.2 10.2 11.4 8.5 9.5 12.0 6.0 10.8 14.2 13.5 14.1 10.1 0.6 2.8 2.4 6.0 3.3 5.8 5.1 4.4 5.4 5.9 4.0 4.8 5.4 1.2 8.4 3.0 4.5 3.9 3.7 18.8 21.8 11.9 17.9 14.6 13.6 15.7 9.5 12.3 11.8 0.0 1.3 2.7 1.1 1.0 5.0 7.8 2.5 2.7 1.2 5.2 3.9 4.1 5.0 2.5 0.6 3.8 2.3 0.0 2.4 4.2 1.6 2.2 1.1 6.7 4.4 1.6 4.6 2.5 3.7 1.1 1.1 1.6 1.7 2.8 4.3 3.6 2.8 6.6 2.1 2.1 4.4 0.0 1.2 0.7 2.4 1.1 2.4 1.8 6.3 1.6 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: AB_2677476, HPA048071: AB_2680248" "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavorable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 4.1 5.6 8.1 25.2 10.4 37.8 6.4 17.2 10.6 6.5 9.2 6.5 8.7 12.0 6.8 6.1 11.0 7.8 6.9 2.6 6.3 5.3 6.0 6.2 5.9 18.6 7.7 7.4 10.8 10.3 9.1 9.7 11.7 8.1 7.5 6.0 4.6 7.2 7.9 6.1 12.5 12.8 3.6 7.1 11.2 6.7 15.1 11.5 34.7 10.7 12.1 16.9 6.6 8.6 10.4 1.3 2.0 5.6 10.9 11.5 4.8 15.8 20.4 21.9 14.1 0.9 1.1 15.8 9.2 6.8 14.8 16.4 11.5 15.6 28.7 5.7 3.9 4.1 10.7 9.0 9.0 6.4 15.4 15.5 17.7 14.4 14.9 0.3 22.0 14.7 2.0 0.7 7.9 1.2 1.9 7.9 17.5 15.0 10.8 7.5 12.7 35.1 32.7 12.4 17.1 4.7 30.3 17.1 14.1 4.6 24.2 13.8 13.8 11.1 13.0 3.1 5.2 8.4 16.9 7.8 11.8 20.0 9.9 14.3 10.7 16.8 29.2 4.8 12.4 13.1 0.0 1.4 2.0 7.6 5.6 6.8 10.3 8.4 7.6 1.3 10.4 11.5 8.0 1.1 10.9 2.7 1.2 8.9 4.8 8.1 10.4 17.2 10.6 6.3 5.3 7.7 7.4 8.1 11.5 3.0 9.9 14.6 6.7 7.3 17.6 3.9 2.5 25.4 12.5 3.5 9.8 16.2 6.6 5.1 17.7 5.5 4.5 0.0 4.5 29.3 5.0 2.8 5.8 3.9 13.9 7.9 0.0 4.3 5.2 6.4 2.0 5.8 3.3 10.8 6.8 11.9 3.5 5.8 1.8 3.7 11.6 12.9 4.9 9.8 28.5 8.0 8.4 11.4 8.1 5.5 LIG3 LIG2 ENSG00000005156 "DNA ligase 3" P49916 17 34980494-35009743 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006723 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA006723: AB_1847781" "unprognostic (6.05e-3)" "unprognostic (2.98e-1)" "unprognostic (1.24e-1)" "unprognostic (2.83e-1)" "unprognostic (1.57e-1)" "unprognostic (8.76e-2)" "unprognostic (2.40e-2)" "unprognostic (2.78e-1)" "unprognostic (2.25e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-3)" "unprognostic (1.31e-1)" "unprognostic (6.67e-3)" "unprognostic (3.39e-1)" "unprognostic (3.28e-1)" "unprognostic (3.29e-2)" "unprognostic (4.71e-2)" 8.8 11.5 10.7 9.8 17.0 9.2 12.5 15.9 18.3 14.7 11.5 15.8 11.4 8.4 21.5 12.3 14.2 17.3 7.9 11.0 14.2 8.0 9.8 11.8 9.8 9.6 9.1 11.7 17.8 15.4 22.9 13.3 16.5 9.3 16.5 13.1 11.8 14.3 13.9 17.0 13.9 9.8 14.7 8.0 14.3 11.6 27.8 10.9 20.8 14.5 9.7 13.9 13.6 12.7 4.6 10.1 4.8 6.3 11.1 8.4 4.5 7.9 15.8 19.1 16.8 3.8 4.7 14.6 7.7 5.6 10.4 10.5 7.6 4.3 13.0 6.4 10.0 10.3 7.4 21.6 9.9 13.5 6.1 14.5 13.6 7.6 11.0 6.0 21.2 24.1 3.5 8.7 7.7 12.1 5.2 12.6 20.0 21.3 14.9 7.5 8.9 26.7 6.8 18.3 9.9 6.7 14.5 17.5 13.7 5.1 8.6 15.6 11.2 11.5 9.4 7.4 29.3 17.0 10.7 6.0 6.8 8.5 8.3 12.3 13.4 14.4 16.8 4.9 10.1 13.0 0.6 3.8 4.8 5.9 6.3 8.4 4.6 4.0 5.2 10.1 4.0 5.4 3.8 0.3 11.1 3.2 6.0 2.5 4.5 10.7 17.0 15.9 18.3 14.2 8.0 9.1 11.7 9.3 10.9 3.0 10.1 1.5 8.9 4.4 16.2 8.7 10.2 4.0 13.6 12.2 15.7 12.3 8.3 5.8 35.6 3.9 6.2 0.0 5.2 15.3 5.4 10.6 9.2 7.3 7.0 15.9 6.4 3.7 5.9 51.3 6.6 4.5 3.3 3.6 8.2 8.5 3.7 7.0 7.4 5.7 16.8 6.5 3.9 29.6 15.8 4.5 18.1 4.9 9.7 8.4 LIG4 ENSG00000174405 "DNA ligase 4" P49917 13 108207439-108218368 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Ciliated cells: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001334, HPA057325" Approved Supported "Nucleoplasm,Cytoplasmic bodies" NA NA Nucleoplasm "Cytoplasmic bodies" "HPA001334: AB_1078689, HPA057325: AB_2732608" "unprognostic (9.93e-2)" "unprognostic (1.56e-1)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (1.40e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.21e-3)" "unprognostic (1.94e-2)" "unprognostic (3.04e-1)" "unprognostic (1.82e-1)" "unprognostic (1.50e-2)" "unprognostic (9.03e-3)" 8.8 12.4 11.6 10.4 15.9 4.3 9.1 14.2 20.6 5.4 7.1 10.2 7.8 8.9 5.8 11.4 8.1 5.9 8.7 8.8 15.6 14.4 11.2 16.7 8.7 12.7 15.5 10.6 7.9 8.3 17.0 20.3 8.3 19.6 7.5 8.7 3.8 6.7 7.1 9.5 6.6 8.6 8.4 14.4 12.6 9.7 11.7 13.6 18.6 10.0 5.4 10.2 8.1 5.3 3.3 2.1 6.8 10.7 2.7 2.7 1.5 8.9 3.4 9.2 6.1 7.7 8.3 3.3 8.8 6.7 6.7 8.1 4.0 4.0 15.2 7.2 5.8 8.3 3.7 6.1 5.9 11.8 8.9 5.8 7.1 7.8 2.1 9.2 9.5 7.6 7.5 9.9 6.5 5.9 6.5 8.0 28.1 2.5 2.8 10.4 4.8 15.8 7.0 2.3 7.3 2.1 14.5 3.6 2.4 8.9 5.7 5.8 6.0 1.9 5.4 6.6 7.5 4.6 14.8 11.9 4.0 4.4 4.5 7.9 7.5 4.9 24.7 15.5 5.5 9.1 0.8 2.3 6.8 1.8 3.8 2.5 2.6 2.0 1.9 2.1 3.3 2.0 2.7 3.2 2.7 10.7 1.4 2.7 1.5 11.6 15.9 14.2 20.6 15.6 14.4 15.5 10.6 19.6 13.6 8.9 7.4 2.4 2.3 2.4 9.6 10.1 0.0 26.8 11.4 1.8 7.9 1.9 8.3 4.6 9.5 3.6 4.1 0.0 6.5 1.0 2.3 3.0 3.5 7.8 5.0 17.5 9.2 4.3 7.3 3.6 2.6 5.0 1.7 8.2 4.6 6.9 6.8 5.3 5.6 5.6 12.6 12.9 2.5 16.4 2.7 5.0 1.5 2.5 2.8 2.0 MARS "CMT2U, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 118.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Enhanced Cytosol NA NA 21000 Cytosol "CAB017097: , HPA004125: AB_1079312" "prognostic unfavorable (1.73e-4)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (8.47e-2)" "unprognostic (1.73e-1)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" 23.8 26.7 35.1 27.3 29.1 23.0 19.8 25.1 36.0 17.4 23.9 23.1 23.9 17.3 23.3 36.3 29.5 17.9 16.1 25.0 28.0 29.5 20.5 45.9 24.3 25.1 40.1 25.5 25.8 48.3 35.7 34.0 22.2 30.9 25.6 24.7 19.8 26.0 30.0 24.5 18.4 20.1 33.7 30.7 30.7 31.3 29.6 30.9 21.4 26.9 22.3 34.3 24.3 27.9 12.9 29.3 19.0 27.0 14.1 18.9 15.5 16.8 23.4 15.7 27.1 17.6 10.7 28.9 24.1 28.2 25.5 27.3 25.1 18.7 29.6 16.0 29.2 15.9 19.2 35.7 31.1 26.8 25.6 15.5 20.9 8.7 14.1 39.2 31.4 24.0 15.5 48.4 29.2 75.7 12.2 18.2 37.8 32.3 63.4 17.7 23.3 28.1 23.7 29.6 27.0 25.8 24.4 118.3 30.6 19.2 13.2 20.9 21.3 12.5 19.3 33.4 18.4 25.4 41.2 13.5 9.2 27.3 13.3 14.3 58.2 58.8 35.7 22.7 23.9 31.5 12.1 14.6 19.0 18.9 27.0 17.2 12.9 12.9 17.1 29.3 7.7 11.1 15.2 7.2 14.1 21.8 28.4 13.1 15.5 35.1 29.1 25.1 36.0 28.0 29.5 40.1 25.5 30.9 30.9 35.7 22.7 29.8 15.6 16.6 14.8 10.1 12.7 28.1 29.6 17.4 31.4 24.6 5.0 32.2 19.0 13.7 11.1 0.0 39.9 18.6 15.5 18.1 26.7 11.3 17.0 6.4 14.5 8.0 12.0 6.6 12.0 22.6 3.3 32.5 10.3 11.5 33.5 14.0 14.2 9.8 28.8 12.9 17.9 33.4 34.1 14.1 31.8 20.3 9.7 23.1 MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708387 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Basal keratinocytes: 15.1;Suprabasal keratinocytes: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain NA NA "HPA035589: AB_10601870, HPA035590: AB_2674693" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.12e-4)" "unprognostic (2.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.53e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.86e-3)" "prognostic favorable (6.14e-5)" "unprognostic (1.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-2)" "unprognostic (8.74e-2)" 5.9 12.1 5.8 8.4 11.4 6.0 9.9 9.6 10.6 3.8 10.0 6.9 3.3 8.9 5.3 3.0 12.3 4.9 5.1 7.7 7.8 5.0 7.9 14.1 4.9 12.1 17.8 5.5 4.0 14.6 6.7 3.4 5.0 9.3 4.5 9.9 3.2 11.4 6.0 12.1 7.4 8.8 5.1 10.8 10.9 7.7 5.5 12.0 6.1 6.0 9.9 12.3 6.3 5.4 4.1 4.8 0.8 4.8 9.9 8.1 4.3 3.8 4.6 4.5 7.5 4.3 2.1 8.4 2.9 2.3 5.7 4.3 11.9 3.6 24.4 4.4 1.7 3.0 7.3 15.6 6.4 6.1 6.6 9.1 14.9 5.3 10.4 4.0 21.9 7.2 2.2 8.2 3.8 6.6 1.5 3.7 7.2 17.4 8.8 3.2 6.5 11.1 10.4 7.7 9.0 11.9 11.5 4.7 17.1 6.8 6.9 7.9 3.8 3.7 10.1 6.6 6.1 4.3 7.7 2.9 4.7 3.7 3.5 8.6 5.8 4.3 20.1 3.5 13.4 4.3 0.0 3.0 0.8 5.5 4.8 6.5 3.5 4.6 4.9 4.8 4.1 7.6 8.1 0.1 9.9 2.3 3.4 8.0 4.3 5.8 11.4 9.6 10.6 7.8 5.0 17.8 5.5 9.3 12.0 0.0 0.6 3.2 4.0 15.1 1.5 1.6 0.0 1.4 1.2 3.5 0.0 1.6 5.0 2.4 2.1 1.6 1.2 0.0 1.5 0.9 1.5 1.2 4.6 6.7 2.2 0.0 0.0 1.8 1.3 0.0 1.4 0.9 5.0 1.8 1.9 0.8 1.2 2.9 0.4 3.7 2.5 0.0 2.7 3.1 2.9 16.6 0.7 4.4 4.2 3.9 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 53.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 25.1 26.0 14.1 10.4 16.4 9.0 24.6 23.1 20.6 9.0 12.6 15.1 10.1 12.6 11.0 11.4 15.8 9.5 11.6 24.4 12.2 10.1 42.4 41.1 13.8 8.0 17.0 14.4 12.8 32.3 10.2 15.8 5.5 13.4 11.4 13.7 9.9 14.2 15.6 19.4 11.5 10.1 11.3 10.5 8.3 17.7 8.9 16.4 8.9 14.0 8.5 13.2 23.2 9.5 13.1 19.4 17.1 11.3 18.9 11.6 7.6 14.2 5.4 3.4 3.6 15.1 6.9 7.0 6.6 9.2 7.2 8.2 7.5 5.7 15.8 10.7 5.8 12.6 7.4 5.2 4.3 9.3 5.3 5.8 13.4 6.2 7.9 10.0 8.9 7.7 7.8 5.0 3.4 7.8 4.9 9.7 13.9 7.4 8.3 8.1 11.7 8.7 4.5 3.9 22.4 6.0 7.2 7.8 20.2 10.6 22.7 7.7 5.6 25.2 34.7 7.1 3.7 53.1 12.7 4.7 5.6 4.5 4.4 9.7 8.5 15.5 16.0 6.1 12.9 5.2 8.5 9.7 17.1 8.3 11.3 9.4 13.1 10.8 9.0 19.4 11.1 11.6 10.4 1.6 18.9 11.2 12.7 6.8 7.6 14.1 16.4 23.1 20.6 12.2 10.1 17.0 14.4 13.4 16.4 8.9 42.2 11.0 15.2 6.3 10.8 27.0 33.1 25.4 13.6 26.2 9.8 24.8 28.2 16.0 4.4 5.2 9.2 0.0 14.9 3.5 6.7 11.8 7.0 30.1 14.2 7.9 5.8 5.5 9.7 4.1 8.1 11.7 6.8 10.0 11.7 12.1 18.1 19.5 9.9 36.0 11.4 6.5 8.1 6.4 3.2 5.1 23.7 10.1 22.9 19.4 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658704 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 74.3" "Cell type enhanced" "Detected in many" 4 "Hepatocytes: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 12.4 29.4 9.2 11.8 13.6 2.7 30.5 7.9 10.0 11.2 15.3 12.2 15.1 13.0 9.7 20.0 14.5 9.1 12.3 74.3 7.6 8.1 35.6 61.9 8.4 11.6 7.8 8.0 9.6 18.9 14.1 10.3 15.1 13.4 24.6 18.1 12.8 20.6 29.4 17.6 10.8 14.1 7.8 17.0 11.0 13.6 6.9 6.9 9.4 22.2 13.3 14.3 15.7 8.5 8.8 16.7 1.7 11.5 12.9 10.2 6.7 11.9 16.5 7.1 27.1 7.6 7.8 12.1 5.7 9.6 11.8 8.5 28.9 15.2 27.7 21.0 8.3 9.2 9.9 12.3 19.0 14.8 14.7 15.7 15.0 8.5 31.7 13.3 7.4 14.3 10.0 10.0 10.8 8.6 5.3 10.3 8.0 18.9 10.4 8.1 32.6 0.1 13.6 9.3 10.5 9.3 14.5 20.4 40.7 30.6 21.6 11.2 12.4 24.9 36.9 12.1 3.5 30.6 18.9 7.5 4.8 7.5 8.7 15.3 7.5 13.8 17.2 7.9 20.7 11.9 1.7 7.4 1.6 6.1 11.5 7.9 8.8 7.9 6.9 16.7 8.6 8.0 8.7 1.2 12.9 6.8 7.4 10.2 6.7 9.2 13.6 7.9 10.0 7.6 8.1 7.8 8.0 13.4 6.9 14.9 23.4 22.9 14.2 11.7 12.8 60.9 17.8 16.0 18.2 15.7 5.9 40.3 18.3 18.3 3.1 14.2 19.6 0.0 16.1 19.0 8.9 25.3 12.7 79.8 15.6 3.2 28.4 8.0 10.8 7.4 12.7 12.2 11.8 19.0 22.7 19.0 14.2 17.5 19.1 48.4 11.4 6.5 9.1 3.9 13.3 12.0 53.2 12.9 28.8 18.5 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" P11586 14 64388031-64463457 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Ligase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 121.6" "Cell type enhanced" "Detected in many" 8 "Hepatocytes: 125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes 250000 Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 18.9 9.0 8.1 8.4 18.1 9.7 12.2 5.7 15.9 7.1 9.3 9.0 4.0 7.5 8.5 6.9 12.0 6.7 6.4 10.6 8.4 6.5 20.5 121.6 6.8 9.2 8.0 10.4 10.1 13.4 13.1 5.6 5.6 10.0 5.5 11.4 9.3 11.6 5.6 26.5 7.6 7.3 8.8 6.9 8.3 7.9 2.3 7.4 15.6 8.6 14.0 12.5 8.7 7.3 21.1 12.8 0.5 13.2 12.8 14.9 8.4 72.5 41.3 15.7 34.2 16.9 13.8 25.5 28.5 19.6 37.0 36.7 40.1 33.4 30.5 13.5 16.9 18.6 35.7 48.4 28.3 43.3 30.3 31.9 37.8 41.4 30.4 12.5 29.0 20.6 10.7 9.2 33.0 17.9 15.3 23.0 30.9 28.1 25.1 28.0 60.2 46.7 17.0 28.7 46.2 43.8 37.3 54.6 27.6 27.8 42.5 34.0 13.2 47.6 25.9 14.3 15.3 40.3 14.7 14.1 27.9 48.4 25.7 34.1 16.8 20.6 53.8 25.6 33.5 31.6 0.2 8.2 0.1 8.1 13.2 10.9 21.1 9.0 9.9 12.8 11.6 7.6 10.1 0.5 12.8 10.3 3.2 14.9 8.4 8.1 18.1 5.7 15.9 8.4 6.5 8.0 10.4 10.0 7.4 17.9 26.3 11.5 9.9 12.2 0.0 38.1 17.8 12.0 20.5 15.7 0.0 20.0 34.9 15.4 0.9 9.9 5.2 0.0 9.0 24.2 10.6 8.3 49.7 125.3 21.6 0.0 2.9 7.4 11.3 0.9 12.0 10.9 13.5 14.4 11.9 0.0 10.8 2.9 12.4 49.9 0.0 19.4 18.6 0.9 7.5 9.4 8.2 20.0 21.3 9.9 MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865549-151101887 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Extravillous trophoblasts: 107.1;Syncytiotrophoblasts: 61.6;Urothelial cells: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" 10.4 10.6 8.0 12.1 8.1 12.2 7.1 32.4 10.5 6.5 6.2 7.8 10.2 3.4 8.5 7.2 6.4 8.0 7.3 10.7 7.5 7.9 9.5 6.9 17.1 11.0 12.3 7.6 22.2 13.7 7.1 9.1 15.5 8.5 5.0 9.1 12.7 3.4 10.5 2.5 5.7 4.7 10.9 10.2 8.7 5.6 13.6 6.6 6.7 12.2 5.0 11.4 8.7 5.1 1.1 3.0 0.2 0.8 1.0 5.0 0.6 12.0 10.5 13.7 33.7 3.6 12.6 33.5 19.0 20.8 19.1 23.6 21.1 11.3 44.5 12.7 29.0 11.3 12.9 21.9 18.5 23.8 18.3 19.9 18.5 18.7 19.3 22.6 33.8 3.0 14.9 23.7 18.5 33.8 17.2 31.9 24.9 43.9 23.3 19.6 25.4 16.5 7.0 14.0 12.1 9.7 19.8 10.2 19.8 12.9 5.9 13.7 10.2 25.1 11.1 15.5 13.0 3.5 23.7 24.2 12.8 28.1 28.4 26.9 19.4 18.0 46.4 21.3 31.6 16.5 0.2 0.7 0.0 0.8 0.8 1.3 0.8 1.9 2.1 3.0 1.1 1.8 1.9 0.0 1.0 0.8 1.5 5.0 0.6 8.0 8.1 32.4 9.5 7.5 7.9 12.3 7.6 8.5 6.6 0.0 1.7 10.7 5.1 5.8 0.0 2.4 2.5 4.0 2.3 14.0 0.0 18.7 6.6 10.4 19.2 7.1 0.9 0.0 15.4 107.1 15.4 4.1 0.0 1.0 21.7 0.0 1.2 3.7 2.4 3.4 0.6 10.1 33.7 1.0 2.5 0.0 15.0 0.8 7.4 12.2 0.0 0.0 6.1 0.5 6.4 3.0 61.6 3.2 3.5 39.1 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Enzymes, Predicted intracellular proteins" Ligase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.7;liver: 120.9" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 163.6;monocytes: 231.8;Proximal tubular cells: 140.3;Syncytiotrophoblasts: 212.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 88.7" "Group enriched" "Detected in all" 5 "granulocytes: 88.7;monocytes: 25.4" "Low cell line specificity" "Detected in many" "HPA008067, HPA054177" Approved Supported Cytosol NA NA Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 10.0 6.6 4.5 7.6 4.4 2.5 5.7 3.9 2.8 4.4 12.4 3.7 6.8 8.3 4.3 6.2 4.5 4.0 7.9 5.2 4.1 5.0 27.9 120.9 6.4 5.4 5.5 1.7 3.3 18.8 11.4 9.4 13.9 3.9 8.6 3.7 6.5 10.6 7.6 6.0 1.9 18.3 4.4 6.1 7.6 6.3 5.9 3.3 5.3 12.0 3.1 5.7 4.0 9.9 9.7 9.3 88.7 25.4 12.4 12.6 13.8 10.9 27.7 2.5 1.4 9.8 8.3 11.2 7.7 10.1 13.5 10.3 21.5 21.6 13.8 23.4 9.5 12.1 17.7 23.6 7.5 10.3 14.3 15.7 11.8 16.1 25.5 17.0 5.5 0.4 12.5 22.1 5.6 14.1 12.6 5.0 12.2 26.1 11.3 10.7 23.6 8.5 23.0 11.8 34.2 10.4 9.3 13.6 20.9 24.6 20.6 6.8 3.2 21.4 12.8 28.2 12.5 16.4 10.2 3.3 5.2 11.0 2.4 5.1 5.7 18.4 13.9 2.6 21.8 4.0 9.8 16.6 43.5 7.7 19.0 9.9 9.7 10.8 9.0 9.3 8.7 12.6 9.7 88.7 12.4 25.4 7.0 11.2 13.8 4.5 4.4 3.9 2.8 4.1 5.0 5.5 1.7 3.9 3.3 17.9 35.3 18.8 8.6 9.5 0.0 0.6 40.8 25.4 18.2 21.0 0.0 57.2 54.7 50.9 1.1 8.4 11.9 0.0 65.9 31.6 13.1 11.4 8.1 163.6 41.2 0.0 16.9 16.5 21.5 1.7 12.7 29.7 20.3 231.8 22.7 0.0 65.8 29.8 14.9 140.3 0.0 12.9 5.1 7.5 7.3 7.0 212.2 35.2 30.5 7.4 NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: AB_2676060, HPA038524: AB_2676061" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (7.30e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.17e-6)" "unprognostic (1.19e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (4.12e-3)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "prognostic favorable (5.10e-4)" 14.5 16.9 10.8 23.2 21.2 39.6 14.0 12.2 18.5 12.4 30.6 21.9 24.1 26.3 15.0 17.5 29.1 16.4 33.1 10.6 10.4 9.5 16.5 24.8 18.1 20.5 22.7 9.2 15.6 20.6 13.5 20.2 17.1 15.6 23.9 25.3 12.9 18.0 17.2 9.8 15.0 36.8 13.6 14.6 30.7 19.2 17.4 20.0 26.4 17.3 21.7 29.8 26.1 17.1 9.5 22.3 12.8 19.7 11.9 12.6 13.1 6.1 14.9 4.8 8.8 14.6 21.4 13.3 12.0 10.9 6.3 6.9 12.7 10.5 5.4 13.7 14.1 8.4 22.1 6.3 17.2 3.3 10.9 5.1 8.8 10.0 14.1 18.3 17.6 17.0 30.3 27.1 8.1 7.4 14.4 22.1 9.8 4.5 7.6 8.9 19.3 8.6 11.5 2.9 27.5 8.7 10.8 15.3 5.3 15.5 28.6 3.6 5.2 8.6 11.3 22.0 7.6 10.0 9.6 26.6 7.0 6.0 12.7 4.6 9.8 4.2 4.6 12.3 10.1 4.8 4.5 19.7 11.8 11.7 17.4 9.9 9.5 10.5 10.6 22.3 7.4 7.0 8.8 12.8 11.9 15.1 16.7 12.6 13.1 10.8 21.2 12.2 18.5 10.4 9.5 22.7 9.2 15.6 20.0 20.8 35.4 18.2 14.5 5.6 6.5 6.9 15.3 14.7 18.2 10.4 3.9 14.5 3.3 15.1 16.8 15.8 63.6 23.3 14.9 11.8 10.8 15.4 20.9 14.4 17.4 12.7 22.5 9.2 22.1 49.9 8.6 20.8 8.5 20.8 28.6 6.9 16.9 54.7 9.6 13.9 7.7 12.9 7.8 16.4 4.3 11.2 14.4 21.3 38.6 20.2 NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.3;SK-BR-3: 23.9;U-937: 18.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 2000000 "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: AB_2665644, CAB068207: AB_2665681, HPA023739: AB_1854308, HPA024017: AB_1854309" "unprognostic (7.08e-2)" "unprognostic (1.55e-1)" "unprognostic (5.76e-3)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (7.65e-2)" "unprognostic (2.19e-1)" "unprognostic (2.84e-1)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.02e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-2)" 9.7 6.4 4.9 9.7 6.2 21.1 13.2 10.7 5.4 6.7 25.2 2.3 9.9 33.0 4.7 4.7 16.4 4.8 15.5 4.9 3.9 2.1 10.7 28.3 8.3 12.1 3.7 0.1 5.9 6.5 2.4 2.8 8.6 4.1 6.9 3.8 5.2 12.8 3.8 7.1 12.4 34.4 5.2 2.2 9.8 11.8 5.5 4.0 3.0 6.8 8.9 9.5 7.6 8.1 0.8 4.7 4.6 8.4 0.5 1.6 2.4 3.4 4.0 0.4 0.8 0.3 1.2 2.6 0.8 0.4 1.3 0.8 3.3 22.3 0.9 6.3 0.2 0.0 7.7 0.2 6.3 0.0 4.1 6.4 5.3 10.5 0.9 2.8 1.3 2.8 0.1 2.2 0.1 0.0 0.0 1.4 4.4 4.9 4.1 0.1 4.3 2.6 2.7 1.0 4.7 2.5 4.6 0.1 11.0 0.9 1.3 1.8 0.4 10.0 23.9 3.0 0.1 0.9 3.1 4.2 0.7 6.4 4.7 1.7 0.5 0.2 1.1 1.1 18.5 3.3 0.0 4.4 4.6 1.6 8.4 0.5 0.8 0.7 1.5 4.7 0.2 0.8 0.7 2.7 0.5 8.4 1.5 0.2 2.4 4.9 6.2 10.7 5.4 3.9 2.1 3.7 0.1 4.1 4.0 32.8 29.7 8.2 53.6 0.0 11.6 7.8 50.9 2.7 17.0 71.5 17.7 41.1 58.0 56.8 30.9 28.6 149.9 23.3 48.4 46.0 12.4 35.0 7.0 99.2 70.9 15.9 10.5 37.4 86.2 46.4 29.7 44.6 0.0 92.0 73.3 27.1 82.3 117.4 20.5 160.6 12.5 12.9 11.5 15.6 17.6 0.0 47.0 17.5 111.6 67.7 NARS NARS1 ENSG00000134440 "Asparaginyl-tRNA synthetase" O43776 18 57600656-57622213 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol NA NA Cytosol "CAB034257: AB_2151043, HPA040017: AB_2676801" "unprognostic (9.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.86e-3)" "unprognostic (1.68e-1)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.23e-7)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.73e-7)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" 30.9 36.9 35.0 28.8 42.6 19.5 31.6 47.1 51.4 28.1 49.7 24.8 31.1 42.5 30.8 31.6 40.2 27.4 26.8 40.6 40.5 36.5 66.0 41.9 26.0 23.0 39.5 39.2 29.4 29.4 52.0 35.7 25.6 49.5 33.1 46.1 18.5 33.7 30.9 76.6 26.9 35.2 29.9 40.6 25.7 36.0 14.9 36.3 25.0 44.5 31.9 29.2 34.6 35.3 20.0 26.6 15.6 40.8 15.8 23.4 23.7 36.6 24.2 22.8 33.3 29.3 22.5 35.6 51.3 26.8 30.3 37.5 17.4 17.2 46.2 24.6 35.5 30.5 41.8 35.8 31.7 44.4 22.4 12.4 35.3 18.6 27.4 49.6 73.2 36.5 23.9 55.5 41.5 39.7 23.8 25.1 28.4 43.3 34.5 34.0 13.6 28.3 17.8 33.5 23.3 19.5 22.5 26.9 39.0 56.6 41.3 25.1 27.5 24.9 32.1 53.8 25.1 17.9 40.7 27.4 33.8 22.6 14.2 37.9 77.5 95.9 44.9 31.1 48.1 39.3 15.6 40.8 14.2 16.4 35.1 20.2 20.0 17.3 17.4 26.6 18.8 23.4 21.2 12.7 15.8 26.6 25.1 17.2 23.7 35.0 42.6 47.1 51.4 40.5 36.5 39.5 39.2 49.5 36.3 71.5 60.9 52.8 56.5 68.6 83.3 195.9 79.0 170.0 72.8 66.3 33.4 91.5 286.8 103.2 11.5 56.6 105.3 93.5 78.8 68.1 57.5 71.7 91.6 94.8 102.8 90.6 60.9 38.1 67.5 12.5 65.3 70.5 74.2 75.7 75.6 85.4 101.4 49.1 73.2 181.5 68.2 71.1 59.4 41.1 41.9 66.1 132.6 49.0 92.8 67.0 NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435961-78574874 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease mutation, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Approved Nucleoplasm,Mitochondria,Cytosol No No "Nucleoplasm, Mitochondria" Cytosol "HPA026793: AB_1848833" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (5.73e-3)" "unprognostic (1.79e-3)" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (4.62e-3)" "prognostic favorable (1.39e-5)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.22e-6)" "unprognostic (8.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" 10.9 16.0 11.8 9.3 11.2 6.4 13.4 19.4 11.8 11.6 13.0 13.1 13.5 12.0 17.6 13.9 10.8 12.0 9.9 12.7 11.3 12.2 22.3 26.8 9.0 10.2 13.4 8.4 15.9 20.0 14.0 17.3 9.4 13.8 13.3 13.3 23.2 12.7 13.2 24.4 9.1 11.1 10.6 10.8 12.6 11.3 11.8 10.3 17.3 16.0 7.7 14.1 9.7 10.7 14.6 13.5 6.7 9.4 16.2 16.6 8.7 7.3 10.3 10.8 7.1 7.6 6.4 9.0 6.1 6.0 9.5 7.9 17.7 7.9 18.2 15.9 3.9 9.2 9.7 18.2 11.9 13.3 11.9 9.8 12.8 8.0 15.0 6.3 13.7 4.8 4.5 7.7 8.4 15.0 8.6 8.1 15.4 19.3 5.0 10.6 8.6 14.2 22.2 11.8 30.0 12.5 14.9 17.7 24.6 12.7 10.4 12.9 8.1 9.1 11.7 15.7 12.2 11.0 5.5 4.9 13.0 15.3 14.8 10.3 8.4 14.1 40.1 2.5 12.4 8.8 6.7 7.9 3.5 9.8 8.3 12.0 14.6 11.3 10.8 13.5 12.6 16.6 14.8 1.7 16.2 9.4 10.3 8.2 8.7 11.8 11.2 19.4 11.8 11.3 12.2 13.4 8.4 13.8 10.3 17.9 17.1 9.0 12.7 11.9 5.3 8.3 2.5 10.7 7.9 5.2 2.0 17.3 24.9 8.2 11.0 6.3 5.0 0.0 6.5 20.2 10.4 14.0 8.1 16.3 10.6 0.0 11.5 2.5 6.5 3.9 7.2 6.1 16.9 1.0 7.7 5.7 6.1 13.3 4.6 22.1 8.7 6.5 8.3 7.4 18.1 12.0 12.8 5.1 13.7 7.5 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464579 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Extravillous trophoblasts: 137.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 340000 Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.16e-1)" 15.5 27.1 21.6 20.4 17.4 21.4 29.3 15.8 20.6 17.5 22.5 18.5 18.4 17.2 19.6 12.6 29.0 19.6 11.4 13.4 16.7 22.6 26.5 63.7 11.3 25.6 26.4 19.2 23.3 27.7 26.2 17.9 24.3 29.8 17.5 30.5 13.1 15.7 16.8 23.8 20.0 16.1 19.4 23.5 19.8 12.8 18.3 15.9 44.9 17.8 26.8 33.1 18.7 18.9 13.7 12.8 3.2 6.4 10.9 14.4 6.7 34.3 25.8 53.3 33.0 11.4 25.9 45.9 29.8 21.6 42.8 42.2 40.9 40.9 79.6 34.7 19.9 23.3 21.3 84.1 43.3 73.4 15.9 29.6 43.2 39.5 45.3 21.9 76.8 19.3 21.9 31.4 45.4 34.3 23.7 35.0 45.7 74.5 29.7 36.8 22.9 88.1 38.5 61.1 66.2 32.3 71.6 22.8 52.3 40.5 24.1 57.3 34.3 29.3 41.0 18.0 45.5 27.1 24.6 18.8 33.9 44.4 33.3 60.8 21.0 18.0 83.7 35.7 56.3 37.3 3.2 3.7 0.3 4.1 6.4 11.8 13.7 11.5 7.3 11.4 8.9 14.4 12.1 0.9 10.9 4.8 12.8 8.3 6.7 21.6 17.4 15.8 20.6 16.7 22.6 26.4 19.2 29.8 15.9 20.8 19.3 31.8 57.8 50.4 26.0 20.9 56.0 21.4 31.8 31.4 5.9 117.2 31.5 30.5 45.8 21.6 14.2 46.7 22.8 137.4 35.6 28.6 20.7 68.6 45.7 27.0 23.8 11.6 15.8 6.6 27.6 17.1 16.9 22.6 34.9 13.2 23.3 7.0 21.9 41.1 22.9 0.0 17.9 39.4 47.7 44.2 45.7 16.0 65.0 44.1 PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764514 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Spermatogonia: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" No No "Nucleoli fibrillar center, Mitochondria" "HPA028308: AB_2672553, HPA028314: AB_10603981, HPA028518: AB_2672653" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "prognostic favorable (1.26e-5)" "unprognostic (1.93e-2)" "unprognostic (1.19e-2)" "unprognostic (1.79e-3)" "prognostic unfavorable (2.34e-4)" "unprognostic (6.48e-2)" "unprognostic (2.72e-1)" "unprognostic (1.14e-1)" "unprognostic (9.42e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.72e-2)" "unprognostic (9.77e-2)" "unprognostic (1.73e-2)" "unprognostic (9.64e-2)" 6.8 8.4 4.7 4.0 8.2 0.5 6.2 5.2 7.9 6.5 9.0 9.5 8.3 6.0 7.9 7.5 7.0 10.4 4.1 6.6 6.5 4.4 9.6 11.3 4.1 5.8 4.5 5.3 11.5 13.6 7.0 6.6 5.6 4.9 7.1 8.3 5.0 7.2 6.9 8.7 6.7 5.1 4.9 4.3 4.9 6.2 11.5 9.4 8.7 6.7 5.9 5.2 6.0 5.2 7.3 8.9 5.3 11.6 8.1 10.5 6.0 4.7 7.8 5.1 6.7 6.3 5.4 11.5 4.0 5.0 7.2 5.2 9.0 3.1 8.3 6.4 3.6 10.5 7.6 9.2 6.4 5.4 5.3 8.3 8.0 4.8 6.6 9.8 4.6 2.8 5.8 9.8 9.3 8.4 6.2 5.3 9.2 14.0 1.1 5.4 5.0 6.4 6.1 11.8 9.0 10.1 5.0 10.1 9.6 6.1 3.4 5.3 5.4 5.8 7.7 10.5 10.3 4.4 5.9 2.8 5.4 5.6 7.6 5.0 8.2 6.9 3.3 4.0 5.5 3.1 1.5 6.6 5.3 6.4 9.7 7.6 6.1 7.0 6.8 8.9 7.3 10.5 7.0 0.6 8.1 11.6 7.1 9.3 6.0 4.7 8.2 5.2 7.9 6.5 4.4 4.5 5.3 4.9 9.4 0.0 0.6 0.5 0.9 0.6 2.1 1.0 2.5 0.0 1.2 0.0 0.0 5.8 8.3 3.9 6.5 0.0 1.7 0.0 2.4 4.0 0.6 1.1 0.0 1.9 2.6 4.8 0.0 0.0 1.2 5.3 3.4 0.7 0.0 1.0 2.5 2.8 2.1 0.0 2.8 4.5 1.3 0.0 0.4 8.1 10.4 0.9 2.7 0.0 4.3 0.6 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848233-66958376 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 41.1;liver: 76.0" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 192.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 3.8;T-cells: 2.9" "Cell line enhanced" "Detected in many" "HeLa: 28.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 96000 Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 41.1 10.7 11.1 2.8 14.6 3.1 12.9 13.1 14.9 2.4 3.8 10.7 21.4 5.6 2.1 2.4 5.0 2.7 2.9 4.0 11.3 8.9 18.7 76.0 2.1 1.6 15.5 11.5 4.4 4.3 19.4 4.0 4.1 10.9 5.4 3.1 3.4 24.2 24.4 5.7 2.8 6.7 1.8 9.4 1.5 3.3 6.1 13.1 0.6 4.2 2.5 2.5 2.2 2.1 0.6 2.6 0.0 3.8 0.3 2.9 2.0 2.9 9.1 3.4 8.3 13.9 5.5 3.5 1.9 7.9 3.6 3.5 4.5 3.3 0.0 3.8 2.9 4.8 3.9 3.8 21.0 1.1 1.8 5.3 4.5 28.3 17.3 10.9 0.0 5.9 21.0 5.4 2.9 6.6 2.3 2.9 7.9 8.5 0.0 1.2 19.4 5.1 2.4 6.4 7.7 7.6 3.8 7.0 1.8 3.3 0.9 7.4 10.5 17.6 9.4 7.2 2.6 7.7 1.2 3.2 4.0 3.7 4.7 2.1 2.0 2.3 0.0 4.1 2.9 3.4 0.0 3.8 0.0 1.2 0.9 1.4 0.2 0.5 1.9 2.6 0.6 2.9 1.6 0.0 0.3 0.5 1.0 1.5 2.0 11.1 14.6 13.1 13.6 11.3 8.9 15.5 11.5 10.9 13.1 0.0 4.8 2.2 1.1 1.1 4.7 3.7 10.2 0.0 1.2 3.5 2.0 15.6 1.7 3.1 15.2 1.4 18.6 0.0 1.6 3.5 1.9 2.4 9.2 192.6 11.2 0.0 8.6 4.3 6.9 39.9 0.6 1.6 5.0 32.5 4.2 9.2 2.3 7.0 3.9 37.8 4.7 0.0 1.4 6.0 4.2 0.5 21.3 1.3 6.0 1.1 PCCA ENSG00000175198 "Propionyl-CoA carboxylase alpha subunit" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 106.7" "Cell type enhanced" "Detected in many" 6 "Distal tubular cells: 84.6;Proximal tubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 54.3;SCLC-21H: 30.1;U-937: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria NA NA 120000 Mitochondria "HPA041716: AB_2677635, HPA047792: AB_2680156" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (1.55e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "prognostic favorable (0.00e+0)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.32e-2)" 15.6 26.2 9.7 11.3 11.1 3.2 12.0 24.0 10.7 12.0 17.5 12.0 14.3 6.7 16.4 106.7 8.8 8.4 7.6 12.4 9.5 7.5 51.3 44.3 8.1 4.0 11.2 8.2 9.7 12.7 5.5 12.4 10.5 12.6 13.1 13.7 11.7 12.2 10.4 10.7 7.7 7.8 17.0 12.0 8.2 16.1 4.7 10.9 4.2 11.9 5.0 6.9 10.8 8.8 3.7 13.0 1.6 10.8 7.3 6.1 4.7 3.3 5.9 9.8 3.2 9.4 8.2 5.5 3.3 5.0 3.1 2.9 7.3 4.5 0.2 5.1 3.2 4.0 3.8 2.9 4.6 5.1 5.5 3.2 7.7 4.2 15.8 5.2 0.3 3.7 7.5 5.0 2.9 4.8 7.6 6.4 4.2 3.0 4.4 5.6 3.6 0.8 17.3 6.1 11.8 2.6 6.7 4.2 5.4 54.3 6.6 30.1 3.6 2.2 12.6 5.5 11.1 9.1 13.7 4.6 3.2 2.7 2.2 2.3 4.3 3.9 0.1 6.1 41.9 2.2 1.5 8.5 1.6 4.6 10.3 6.1 3.7 3.0 4.3 13.0 2.6 4.1 5.1 1.3 7.3 10.8 1.1 6.0 4.7 9.7 11.1 24.0 10.7 9.5 7.5 11.2 8.2 12.6 10.9 3.0 8.3 7.3 25.7 1.6 15.4 8.7 38.2 10.7 10.3 19.2 27.5 21.2 84.6 13.8 14.8 9.9 14.0 0.0 7.3 5.4 7.1 14.3 13.9 41.9 10.3 27.0 3.5 11.6 10.2 7.9 8.1 7.2 5.0 2.8 10.1 10.4 6.2 14.0 12.7 63.9 32.3 12.9 8.9 4.8 4.3 3.3 25.3 4.9 26.5 19.5 PCCB ENSG00000114054 "Propionyl-CoA carboxylase beta subunit" P05166 3 136250306-136337896 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in all" 12 "Early spermatids: 317.0;Late spermatids: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" NA NA 79000 "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 13.0 46.0 14.3 7.7 16.3 12.7 11.8 7.8 19.2 8.1 17.5 21.0 11.6 15.3 7.1 6.4 11.8 8.1 12.5 36.7 14.1 12.6 36.0 80.2 7.7 8.7 18.9 16.4 6.8 20.8 16.2 9.6 10.0 22.3 10.2 17.6 10.0 10.9 10.6 30.5 8.0 11.1 14.1 18.6 7.9 11.5 17.6 15.5 6.3 15.7 12.4 8.1 9.6 6.6 12.4 24.6 3.9 16.6 12.8 14.9 11.5 19.8 14.2 13.7 20.5 10.4 11.5 24.2 10.5 11.4 16.0 22.6 21.1 14.1 24.8 29.3 14.8 14.3 11.1 16.0 14.1 24.3 14.8 13.6 43.5 16.8 31.8 22.2 33.4 19.4 13.6 13.5 10.1 23.1 10.3 17.9 41.8 31.6 13.3 12.2 37.9 33.0 19.6 11.5 30.5 12.9 9.2 11.3 35.5 29.3 21.8 27.3 20.3 26.5 15.8 24.1 12.9 31.3 19.9 13.4 8.0 8.6 22.4 9.2 25.4 21.0 20.7 11.4 13.0 9.3 2.8 16.2 3.9 13.2 16.6 14.9 12.4 8.8 13.6 24.6 10.2 9.0 11.1 1.4 12.8 14.6 21.2 7.9 11.5 14.3 16.3 7.8 19.2 14.1 12.6 18.9 16.4 22.3 15.5 8.9 9.4 10.0 7.3 3.7 15.1 45.4 12.7 18.7 11.4 19.2 9.8 51.9 33.2 19.9 317.0 6.0 14.4 23.3 12.5 19.8 10.3 9.0 28.8 63.8 31.1 11.1 8.7 8.6 13.1 128.9 12.7 15.4 18.6 24.4 12.7 10.3 14.9 14.8 10.3 71.0 13.1 12.9 8.3 10.9 28.8 2.9 42.6 9.6 21.7 8.9 PFAS "FGARAT, GATD8, KIAA0361, PURL" ENSG00000178921 "Phosphoribosylformylglycinamidine synthase" O15067 17 8247618-8270491 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 28.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022140, HPA022886" Enhanced Approved Vesicles NA NA 350000 Vesicles "HPA022140: AB_1855232, HPA022886: AB_1855233" "unprognostic (1.90e-1)" "unprognostic (9.21e-2)" "unprognostic (2.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.59e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (5.47e-3)" "unprognostic (1.08e-3)" "unprognostic (9.51e-3)" "unprognostic (3.63e-2)" "unprognostic (6.57e-2)" "unprognostic (2.88e-3)" "unprognostic (3.85e-1)" 15.4 15.3 11.4 14.8 13.0 17.5 12.8 14.6 18.5 11.2 12.4 14.0 10.0 9.8 15.1 11.2 13.2 13.5 14.3 9.7 9.0 8.0 13.0 17.0 9.5 18.5 10.7 12.6 16.6 15.7 11.5 9.2 10.7 10.7 11.5 12.2 12.0 10.6 10.6 11.6 13.6 11.5 14.3 7.9 18.0 11.4 17.2 11.1 29.5 12.8 10.8 16.2 10.4 9.5 9.2 7.1 28.2 2.9 2.7 6.5 1.1 5.9 26.5 13.6 20.4 5.0 4.1 15.7 7.7 2.9 14.2 10.8 12.9 5.4 26.5 12.5 4.5 5.0 14.0 31.3 10.0 10.6 12.0 25.6 15.5 25.0 16.1 4.3 12.5 11.5 3.9 2.5 16.4 10.4 4.0 11.7 14.5 20.8 4.0 5.7 9.0 22.1 10.9 22.6 3.3 12.1 33.3 14.1 12.7 6.5 10.0 8.3 12.9 9.5 6.1 8.8 7.6 6.0 5.8 8.2 7.9 10.3 14.4 19.0 4.8 8.5 13.0 8.7 17.8 13.3 9.1 2.9 6.5 4.0 2.5 5.2 7.8 5.2 4.6 2.4 9.2 6.5 5.1 28.2 2.7 1.9 7.1 2.7 1.1 11.4 13.0 14.6 18.5 9.0 8.0 10.7 12.6 10.7 11.1 0.0 6.4 2.2 1.5 2.2 6.5 2.8 2.5 8.1 5.7 3.5 5.9 4.2 0.0 3.0 1.6 2.1 1.0 0.0 2.6 3.2 2.3 1.8 1.1 3.8 4.0 1.6 0.0 3.1 3.0 0.4 4.9 2.2 3.3 6.4 2.0 1.5 1.9 3.6 1.4 2.4 6.4 0.0 1.7 3.9 10.3 1.8 2.6 2.5 5.3 1.3 PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Enzymes, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Distal tubular cells: 336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 16000 Mitochondria "HPA031361: AB_10602150, HPA031363: AB_2673844" "unprognostic (1.49e-1)" "unprognostic (6.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.96e-5)" "unprognostic (2.71e-1)" "unprognostic (7.79e-3)" "unprognostic (9.13e-3)" "unprognostic (3.24e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-2)" "unprognostic (6.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-1)" "unprognostic (4.30e-2)" 23.4 36.3 18.9 20.5 21.9 10.7 30.7 12.0 26.0 23.2 32.0 12.4 27.3 25.5 18.2 34.4 31.6 14.5 30.9 22.1 17.8 16.4 41.4 43.9 26.5 28.1 19.3 14.9 19.6 47.0 22.8 16.1 37.6 17.2 27.2 27.3 19.6 36.6 35.0 19.6 21.9 41.0 27.6 18.9 24.4 27.2 13.5 13.4 22.6 31.3 26.0 20.5 24.0 19.4 41.9 44.4 76.1 55.7 42.0 41.0 52.0 22.9 9.6 5.6 8.7 17.4 18.1 20.9 11.6 13.4 15.7 13.9 8.1 28.1 6.9 22.9 14.7 9.1 13.5 3.7 17.6 13.2 18.3 11.1 11.6 10.6 9.6 23.9 11.9 20.6 15.9 31.9 11.0 20.4 19.3 14.5 8.6 4.7 5.0 16.0 13.7 5.8 11.8 6.4 21.2 14.9 6.6 5.7 12.3 34.3 21.7 6.6 7.3 14.2 34.8 36.0 17.0 16.4 52.7 9.1 8.6 11.5 13.1 13.2 16.5 10.3 5.0 3.6 13.8 17.6 58.1 55.7 76.1 30.7 55.1 35.7 41.9 37.0 33.0 44.4 39.9 41.0 34.9 41.2 42.0 51.8 33.2 36.4 52.0 18.9 21.9 12.0 26.0 17.8 16.4 19.3 14.9 17.2 13.4 53.6 69.7 61.9 43.1 20.7 9.2 94.6 86.6 54.9 59.1 61.1 5.9 137.5 336.5 81.6 2.8 50.7 119.1 0.0 120.2 108.8 45.6 37.4 54.4 103.6 97.2 11.1 30.1 43.0 68.9 3.4 56.1 87.5 77.6 111.0 116.6 40.7 82.5 122.6 59.8 254.9 21.8 25.8 44.7 8.4 19.2 31.7 112.6 52.4 93.7 42.7 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase" P47897 3 49095932-49105135 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Late spermatids: 438.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 21000 Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favorable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favorable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" 20.9 16.3 9.7 19.3 10.2 18.4 22.7 15.8 13.2 17.6 27.3 13.1 27.7 17.2 12.3 19.8 35.1 16.4 20.0 22.0 9.8 9.6 27.1 26.0 15.0 33.9 12.4 7.2 21.6 33.8 20.3 13.7 25.7 9.6 16.2 29.9 15.2 31.7 28.7 33.3 26.7 31.8 16.7 11.2 21.1 16.9 30.1 11.3 36.8 16.5 34.8 33.3 19.4 18.5 20.4 40.0 8.9 32.3 21.8 24.0 19.6 18.8 19.2 32.1 45.9 41.3 44.9 33.1 21.0 48.1 41.7 41.0 24.3 24.5 58.4 13.5 34.8 23.4 24.0 45.5 34.6 30.0 16.6 36.3 46.0 30.8 42.3 21.8 37.4 28.4 47.3 30.3 32.1 27.3 44.8 45.5 34.2 20.5 26.0 30.5 10.1 26.9 33.6 27.5 38.6 30.0 17.8 27.0 43.0 28.0 28.1 11.8 32.8 18.6 47.3 28.9 33.0 39.2 43.7 26.2 19.0 27.0 31.3 23.4 22.4 38.1 32.8 19.5 33.7 12.0 8.9 23.1 8.7 13.5 32.3 18.1 20.4 16.8 14.9 40.0 15.2 15.5 15.4 2.6 21.8 26.1 16.9 24.0 19.6 9.7 10.2 15.8 13.2 9.8 9.6 12.4 7.2 9.6 11.3 20.8 57.3 55.9 52.1 59.8 10.1 50.4 40.8 22.7 35.2 38.4 9.8 160.6 58.0 67.5 150.2 50.3 110.2 23.3 94.9 127.6 48.0 47.5 38.1 41.8 85.6 19.1 62.3 50.3 98.5 438.0 54.4 55.2 45.5 120.0 127.2 20.6 67.1 71.9 34.3 63.0 13.0 45.3 43.4 18.4 46.6 75.3 156.4 69.2 176.8 57.2 QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "B-cells: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 32.6;naive B-cell: 26.1" "Lineage enriched" "Detected in all" 7 "B-cells: 32.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome NA NA Vesicles Centrosome "HPA029585: AB_10599823, HPA029587: AB_10602311" "unprognostic (1.86e-3)" "unprognostic (5.58e-2)" "unprognostic (6.19e-3)" "unprognostic (3.45e-1)" "unprognostic (2.11e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.46e-1)" 9.8 10.8 12.4 17.0 14.7 8.5 15.6 10.1 15.6 7.6 11.7 10.1 11.9 11.3 9.5 10.8 10.3 8.5 8.3 13.9 10.4 9.1 15.5 12.5 7.7 21.0 15.8 8.3 10.2 10.8 10.9 11.9 8.7 9.9 8.3 13.7 7.5 10.6 12.5 35.7 8.8 14.8 8.8 11.9 16.7 11.0 10.6 13.7 13.8 13.7 14.6 21.3 8.9 8.6 32.6 4.0 1.6 4.5 2.6 3.1 2.2 6.2 6.5 9.0 13.0 5.8 7.3 12.7 7.1 7.4 9.6 9.6 7.5 5.2 20.9 6.6 7.9 9.9 11.1 13.3 8.6 12.1 9.9 10.2 10.1 6.9 7.8 9.1 22.9 9.1 7.2 13.5 10.2 15.1 7.3 6.8 13.2 18.4 6.8 7.9 7.0 7.3 11.2 9.3 10.9 7.6 20.1 11.5 5.3 10.4 7.2 7.8 8.0 5.7 13.4 10.5 8.2 8.7 17.8 6.6 6.8 5.6 7.2 11.0 4.0 5.6 12.2 9.3 15.6 10.0 1.6 2.4 0.4 2.6 3.6 2.5 32.6 2.9 2.2 4.0 26.1 2.7 2.6 0.7 2.6 4.5 3.2 3.1 2.2 12.4 14.7 10.1 15.6 10.4 9.1 15.8 8.3 9.9 13.7 17.9 8.4 62.4 6.4 3.5 14.2 24.6 10.2 26.8 7.9 10.4 15.7 18.2 14.9 13.3 10.4 10.4 10.5 0.0 15.9 19.4 7.2 6.4 17.4 13.0 11.3 3.2 16.7 8.0 13.2 4.5 7.8 9.0 8.5 14.4 10.5 9.4 12.8 7.0 8.5 14.6 18.7 0.0 6.6 20.7 12.0 4.6 10.3 11.4 19.0 8.4 RARS DALRD1 ENSG00000113643 "Arginyl-tRNA synthetase" P54136 5 168486445-168519299 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003979, HPA004130" Approved Enhanced Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA003979: AB_1856083, HPA004130: AB_1856084" "unprognostic (1.06e-2)" "unprognostic (1.92e-2)" "unprognostic (2.74e-3)" "unprognostic (2.82e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.59e-5)" "prognostic unfavorable (1.10e-8)" "unprognostic (3.26e-3)" "unprognostic (5.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.92e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.43e-2)" "unprognostic (2.35e-1)" "unprognostic (2.39e-1)" "unprognostic (1.33e-2)" 21.8 26.3 16.0 18.3 15.3 6.2 22.6 17.1 18.4 21.2 29.4 9.1 20.4 33.3 22.9 21.4 34.7 19.5 14.4 21.7 19.8 12.3 29.8 33.5 18.7 18.6 13.9 15.2 21.3 33.0 19.9 34.5 30.3 15.8 18.9 27.4 15.5 34.0 15.4 27.8 27.9 48.7 21.5 14.5 22.1 24.4 17.2 11.8 20.5 21.5 32.3 23.7 22.4 22.6 11.1 21.8 5.2 17.7 16.8 16.3 11.7 27.2 32.4 24.0 26.6 33.2 38.1 41.3 40.2 34.6 41.9 49.0 55.0 29.8 29.0 33.0 38.2 43.1 26.5 31.4 54.1 54.7 30.1 21.6 19.5 29.5 34.5 28.8 46.0 20.8 29.2 28.9 45.6 21.9 25.8 33.5 15.9 29.1 14.7 44.8 25.2 19.1 18.3 39.4 24.0 22.1 8.4 35.0 27.6 37.3 31.1 22.9 28.2 30.7 35.5 41.5 30.5 32.3 19.3 33.2 30.4 27.9 23.4 46.8 14.7 26.9 29.8 33.1 32.9 28.8 3.4 14.4 5.2 12.5 17.7 14.3 11.1 12.6 13.3 21.8 6.6 15.6 16.3 4.0 16.8 16.4 10.3 12.8 11.7 16.0 15.3 17.1 18.4 19.8 12.3 13.9 15.2 15.8 11.8 53.6 32.3 25.1 37.6 26.3 25.0 43.6 35.7 46.8 39.8 24.4 25.5 88.8 14.9 80.1 16.6 27.5 40.6 23.3 83.1 79.2 34.8 24.5 26.6 31.4 51.1 12.7 12.6 33.2 24.6 11.6 23.0 35.0 27.0 72.1 36.7 22.7 61.2 38.7 23.0 36.0 22.7 19.4 28.9 27.7 42.2 31.1 70.5 20.1 44.8 35.2 RARS2 "DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL" ENSG00000146282 "Arginyl-tRNA synthetase 2, mitochondrial" Q5T160 6 87514378-87590003 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039987, HPA042645" Uncertain Approved Mitochondria NA NA Mitochondria "HPA039987: AB_2676786, HPA042645: AB_2678097" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (6.98e-2)" "unprognostic (9.27e-2)" "unprognostic (5.41e-2)" "unprognostic (6.61e-2)" "unprognostic (4.30e-2)" "unprognostic (1.88e-1)" "unprognostic (1.08e-3)" "unprognostic (8.28e-2)" "unprognostic (2.20e-1)" "unprognostic (7.56e-3)" "unprognostic (1.62e-1)" "unprognostic (1.89e-2)" "unprognostic (5.73e-2)" "unprognostic (7.16e-3)" 27.0 44.1 13.3 21.1 15.9 16.0 22.9 24.0 17.3 25.1 21.4 18.6 25.2 17.5 35.5 25.5 20.4 21.1 19.2 21.5 14.4 12.8 23.7 32.1 20.5 24.4 17.3 14.2 22.2 30.1 20.5 36.9 28.3 17.2 20.7 23.1 24.0 23.5 27.7 23.0 20.4 30.5 24.7 16.8 21.1 20.5 23.9 13.6 28.0 21.2 20.5 27.3 24.3 20.2 16.7 18.9 22.8 20.2 18.1 28.8 16.2 10.1 10.1 24.3 26.4 24.7 27.0 17.3 24.4 29.2 16.9 21.5 19.4 11.4 12.9 14.5 25.0 17.1 14.2 20.4 14.0 24.0 9.5 19.3 13.3 12.8 30.8 31.1 15.7 11.5 26.9 13.6 14.2 18.1 23.7 22.2 13.6 30.7 12.8 24.9 18.7 5.1 16.7 15.8 21.8 10.9 10.3 24.5 11.3 20.8 21.4 22.0 29.7 12.8 6.4 17.1 21.4 11.9 24.0 15.1 11.2 9.0 12.3 20.1 13.6 22.8 10.7 17.6 16.6 19.4 15.9 19.1 22.8 18.1 19.3 21.3 16.7 23.4 17.0 16.7 16.2 23.0 19.1 11.6 18.1 20.2 18.9 28.8 16.2 13.3 15.9 24.0 17.3 14.4 12.8 17.3 14.2 17.2 13.6 17.9 14.1 14.5 30.7 15.3 13.2 19.7 7.6 20.1 26.1 10.4 19.6 27.0 38.1 25.7 69.3 24.2 16.2 0.0 41.3 37.9 29.7 24.9 17.4 13.2 18.2 6.4 8.6 22.7 14.8 27.7 23.6 14.2 18.6 22.6 23.2 12.1 29.9 21.8 22.6 23.7 15.6 25.8 24.7 38.7 31.1 15.7 33.1 21.8 24.1 29.1 RIMKLA "FAM80A, MGC47816, NAAGS-II, RP11-157D18.1" ENSG00000177181 "Ribosomal modification protein rimK like family member A" Q8IXN7 1 42380795-42422578 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 41.2;Horizontal cells: 33.4;Rod photoreceptor cells: 23.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 7.8;JURKAT: 6.3;Karpas-707: 9.1;SCLC-21H: 11.9;U-266/70: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027826 Uncertain Uncertain "Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" "HPA027826: AB_10603992" "unprognostic (4.04e-2)" "unprognostic (1.61e-1)" "unprognostic (3.68e-3)" "unprognostic (9.84e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (2.63e-3)" "prognostic favorable (1.43e-4)" "unprognostic (8.89e-2)" "unprognostic (3.76e-1)" "unprognostic (9.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" "unprognostic (7.07e-2)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" 0.9 1.2 6.2 1.5 10.4 0.8 1.3 7.8 18.4 1.0 7.9 1.7 0.0 1.4 1.0 0.8 1.0 0.9 1.8 8.5 7.5 5.9 2.5 0.7 5.4 0.8 7.9 8.5 0.7 2.5 6.6 2.0 1.3 20.1 2.2 9.0 3.3 1.1 1.2 1.4 1.1 1.3 2.4 3.6 1.1 2.1 2.3 1.2 0.0 2.2 0.0 0.8 1.1 0.4 0.3 1.6 1.3 0.2 0.4 2.0 0.1 0.0 0.8 0.1 7.8 0.1 0.0 1.5 0.0 0.0 0.2 0.5 0.4 0.2 0.0 1.6 0.0 1.3 0.0 4.6 0.0 0.4 4.1 3.1 0.3 0.1 1.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 9.1 0.0 0.3 2.1 0.0 4.0 0.6 5.5 0.0 0.3 0.4 0.7 2.1 11.9 5.1 0.4 0.3 0.1 0.9 0.4 2.0 0.0 0.0 0.4 0.0 0.8 8.3 4.7 5.5 0.1 0.0 0.0 1.1 0.2 1.3 0.2 0.2 2.0 0.2 0.1 1.0 0.0 0.3 0.1 0.2 1.0 0.4 0.1 1.6 0.1 0.1 6.2 10.4 7.8 18.4 7.5 5.9 7.9 8.5 20.1 1.2 14.9 4.6 0.0 0.8 0.6 13.2 13.0 0.0 0.0 1.2 1.8 41.2 1.0 1.7 3.2 4.7 0.9 7.8 0.0 4.2 11.6 0.3 2.9 0.0 0.0 0.8 33.4 10.9 1.3 0.0 6.4 0.3 0.8 5.0 0.0 7.5 4.5 6.8 5.9 0.0 2.4 23.9 0.0 0.5 1.0 2.5 0.1 1.4 0.0 5.5 0.7 RIMKLB "FAM80B, KIAA1238, NAAGS, NAAGS-I" ENSG00000166532 "Ribosomal modification protein rimK like family member B" Q9ULI2 12 8681600-8783095 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 171.4;Late spermatids: 230.6;Syncytiotrophoblasts: 114.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 31.2;U-698: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059552 Approved "Nucleoplasm,Centriolar satellite" NA NA "Nucleoplasm, Centriolar satellite" "HPA059552: " "unprognostic (5.29e-3)" "unprognostic (2.26e-2)" "unprognostic (1.89e-5)" "unprognostic (2.40e-2)" "unprognostic (2.30e-1)" "unprognostic (3.35e-2)" "unprognostic (6.56e-2)" "unprognostic (8.52e-2)" "unprognostic (8.67e-3)" "unprognostic (1.76e-1)" "unprognostic (3.25e-1)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-2)" "unprognostic (3.02e-1)" "unprognostic (3.74e-1)" "unprognostic (3.99e-1)" 22.5 10.7 15.9 10.7 19.2 15.8 20.1 23.3 21.2 18.1 17.6 16.4 11.2 5.1 35.9 18.2 10.4 25.4 12.5 10.7 17.6 12.8 9.2 3.2 13.9 7.6 10.2 19.0 22.7 7.3 36.2 10.1 21.2 19.9 11.7 6.5 18.0 9.0 13.5 9.5 8.8 8.7 25.5 14.0 11.5 7.7 27.8 12.1 13.6 15.6 4.8 6.4 11.8 18.4 4.0 1.3 5.3 2.9 2.8 3.9 2.5 1.2 7.1 16.5 17.5 2.2 2.0 23.5 6.9 3.3 5.8 4.0 0.6 7.5 10.3 6.5 4.5 6.5 2.6 8.3 9.2 6.5 0.1 5.1 4.8 20.1 0.0 2.6 1.4 4.9 4.3 4.1 5.5 9.6 4.0 7.5 8.7 6.6 0.0 3.6 4.3 9.5 0.6 19.4 0.0 0.4 14.9 22.5 0.0 8.9 3.6 0.5 10.8 7.6 9.8 6.7 31.2 2.1 4.7 14.1 6.1 20.4 3.2 2.2 0.1 0.0 52.5 5.3 0.9 4.2 5.3 2.9 1.2 2.4 1.1 3.0 2.2 2.4 3.5 1.2 4.0 3.9 1.5 0.7 2.8 1.4 1.3 0.1 2.5 15.9 19.2 23.3 19.5 17.6 12.8 10.2 19.0 19.9 12.1 26.8 40.5 5.0 21.6 13.5 20.8 13.7 10.2 41.5 35.2 12.2 0.0 49.9 13.3 12.1 171.4 30.3 2.0 23.3 2.6 14.1 23.7 15.5 11.5 0.0 16.2 12.7 8.6 20.3 7.5 230.6 21.6 7.7 32.1 1.0 2.5 35.5 5.6 2.9 29.0 7.9 3.1 12.9 22.8 49.1 26.8 11.7 114.2 5.1 1.0 15.0 RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266207-100292769 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm NA NA 8700 Nucleoplasm "HPA027982: AB_10601769, HPA027990: AB_2672452, HPA028151: AB_10602099, HPA028331: " "unprognostic (4.79e-2)" "unprognostic (1.17e-2)" "unprognostic (3.97e-2)" "unprognostic (3.82e-2)" "unprognostic (6.76e-2)" "unprognostic (4.12e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (9.55e-3)" "unprognostic (3.64e-2)" "unprognostic (1.12e-2)" "unprognostic (2.46e-1)" "unprognostic (8.09e-3)" "unprognostic (3.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.94e-2)" 20.9 25.0 19.4 17.8 24.9 25.5 20.0 22.6 31.7 14.7 22.9 20.3 19.9 31.7 14.2 26.0 27.0 13.4 19.9 25.5 20.0 21.0 31.7 23.0 16.1 21.8 21.5 20.7 13.3 27.7 21.1 17.2 21.2 33.1 20.9 22.2 14.1 18.5 17.4 35.4 14.6 37.8 15.4 20.5 24.2 21.8 12.2 12.4 25.0 18.3 20.2 20.8 18.7 17.5 9.6 8.0 8.2 19.6 11.0 20.1 7.7 22.0 11.4 11.3 15.2 14.3 23.3 30.9 26.2 12.8 17.1 14.8 18.6 11.1 22.6 19.9 16.6 21.1 11.2 13.8 12.4 20.7 22.6 11.5 14.9 13.0 23.4 22.1 27.1 23.6 18.9 19.6 22.3 29.9 17.0 21.2 16.5 25.6 34.5 25.8 7.3 13.9 21.1 17.3 15.7 22.1 10.0 20.2 9.9 21.0 18.1 9.1 11.4 16.9 24.5 35.8 18.5 5.3 34.8 18.4 16.2 11.3 25.2 31.4 20.0 20.1 18.1 34.0 23.6 9.6 8.2 9.1 7.5 10.8 11.3 13.8 9.6 10.0 12.8 8.0 7.1 9.3 10.5 4.4 11.0 19.6 7.6 20.1 7.7 19.4 24.9 22.6 31.7 20.0 21.0 21.5 20.7 33.1 12.4 6.0 14.4 26.1 13.0 12.0 22.2 49.6 7.6 13.4 10.3 17.4 11.8 48.9 21.6 37.0 11.5 17.5 35.4 0.0 30.2 65.3 13.9 14.2 12.7 15.3 69.5 20.6 18.5 22.7 41.9 6.4 17.8 28.9 15.1 50.5 26.6 20.6 46.7 37.1 12.0 49.6 26.8 6.5 12.3 27.2 14.7 12.8 38.8 32.0 29.7 15.7 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412255 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 43000 Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 26.4 30.1 20.1 20.4 29.7 15.1 29.2 22.9 34.5 25.7 35.6 35.2 32.7 51.6 29.7 25.8 30.8 26.9 22.9 26.4 19.6 24.6 42.4 55.1 23.1 22.7 29.1 26.2 29.0 29.4 38.4 29.9 33.7 36.7 27.0 42.3 27.1 29.9 28.6 40.9 46.6 61.7 31.8 24.4 29.3 29.7 30.8 25.5 32.0 32.7 30.1 46.6 26.5 24.2 44.6 51.5 29.0 47.7 37.0 40.5 44.0 32.2 29.0 36.4 27.3 31.9 23.8 29.0 28.3 34.1 45.3 43.1 37.6 13.2 8.0 19.0 33.0 27.9 22.0 41.6 41.1 58.7 40.4 41.8 22.8 24.6 34.1 22.0 53.3 20.9 23.4 27.3 44.8 43.6 25.0 40.7 22.6 27.0 22.8 33.0 26.9 22.6 18.5 20.8 37.5 26.6 35.2 39.3 41.2 31.1 28.1 37.6 20.8 30.7 19.9 35.9 40.0 21.8 20.7 30.6 25.0 36.9 21.7 27.1 15.9 12.7 28.9 25.9 24.2 32.6 29.0 43.5 27.4 31.7 47.7 35.5 44.6 33.3 33.0 51.5 43.6 39.9 34.6 4.3 37.0 35.5 28.9 40.5 44.0 20.1 29.7 22.9 34.5 19.6 24.6 29.1 26.2 36.7 25.5 29.8 30.2 40.2 48.9 53.8 50.9 32.3 48.4 37.5 22.7 33.2 19.6 98.9 56.3 89.0 3.8 37.9 93.2 0.0 84.1 74.7 40.4 51.2 42.6 54.7 75.2 49.3 44.9 35.0 41.7 7.0 32.5 40.0 28.7 107.4 50.3 61.1 82.4 59.7 44.9 108.7 48.0 25.8 37.2 57.2 58.8 66.5 81.8 30.9 51.3 61.4 SARS SERS ENSG00000031698 "Seryl-tRNA synthetase" P49591 1 109213918-109238169 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Aminoacyl-tRNA synthetase, DNA-binding, Ligase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016939, HPA064668" Uncertain Enhanced Cytosol NA NA 100000 Cytosol "HPA016939: AB_1856585, HPA064668: AB_2685316" "unprognostic (4.92e-2)" "unprognostic (2.61e-1)" "unprognostic (5.87e-2)" "unprognostic (6.78e-2)" "prognostic favorable (9.47e-4)" "prognostic unfavorable (5.75e-4)" "prognostic unfavorable (6.13e-5)" "unprognostic (3.02e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.23e-1)" "unprognostic (2.06e-1)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-1)" "unprognostic (3.85e-2)" "unprognostic (3.45e-3)" 35.8 42.6 46.1 28.2 45.9 16.3 38.3 42.6 60.6 40.1 37.6 31.2 30.9 33.5 39.4 36.0 42.0 39.6 28.7 43.9 55.9 47.3 37.6 58.6 44.5 28.8 46.4 56.0 44.4 68.7 55.3 40.1 44.9 64.1 34.3 41.0 22.0 54.2 42.3 72.3 46.1 31.1 42.9 41.0 29.4 46.0 20.9 35.0 25.3 75.0 32.9 38.7 41.8 60.4 54.3 45.9 48.6 48.3 41.0 66.1 88.9 33.3 13.1 25.2 37.9 37.9 34.4 43.4 35.1 36.4 30.5 38.1 25.3 10.3 36.0 18.2 49.4 17.0 18.3 39.2 49.6 35.5 25.4 23.9 13.9 16.2 18.3 76.2 17.5 15.7 42.3 86.8 35.9 78.3 26.0 36.3 45.5 31.8 45.1 29.6 31.9 19.4 8.9 10.5 20.0 31.0 16.1 32.2 16.1 23.2 17.7 35.0 18.6 16.8 27.1 95.1 20.0 15.3 20.9 28.6 18.2 22.9 25.8 24.5 34.4 13.9 29.5 57.4 19.3 61.8 35.6 44.5 48.6 56.0 48.2 58.4 54.3 59.3 55.4 45.9 52.5 61.8 57.7 21.3 41.0 48.3 29.6 66.1 88.9 46.1 45.9 42.6 60.6 55.9 47.3 46.4 56.0 64.1 35.0 47.6 92.0 61.1 90.9 109.9 51.2 87.9 81.5 66.9 81.9 68.0 21.6 157.2 112.7 120.1 15.1 64.7 75.8 70.0 195.0 122.6 80.4 56.7 96.0 112.9 78.0 55.6 66.7 63.8 59.4 21.0 73.1 68.8 60.8 110.0 61.3 56.1 142.9 49.1 65.4 85.4 34.4 129.4 118.7 46.1 22.4 95.2 157.6 64.0 84.6 77.6 SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930896 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cytotrophoblasts: 34.4;Late spermatids: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" 5.8 16.5 9.9 7.2 12.8 11.1 7.4 10.7 20.4 8.0 9.2 11.3 11.4 12.3 9.0 9.4 12.9 11.5 8.2 12.3 8.3 8.6 13.4 20.6 6.3 11.0 10.9 7.8 9.5 14.4 11.2 11.4 10.7 15.0 11.0 8.5 11.8 13.6 9.9 15.5 15.6 9.9 8.1 7.2 11.3 11.1 8.8 11.5 11.4 13.8 9.5 12.6 11.0 8.3 6.3 12.7 0.4 7.2 6.5 8.0 4.3 5.7 17.4 7.0 4.1 2.9 6.0 9.6 4.0 5.5 9.5 7.5 14.2 7.1 6.5 5.8 5.7 3.8 5.4 7.3 11.4 2.4 5.5 9.4 12.9 7.5 12.2 6.9 11.0 12.9 9.1 6.2 6.2 4.3 4.7 6.7 10.5 11.1 6.4 4.8 12.2 8.3 10.0 7.1 9.0 3.5 12.0 6.3 7.1 10.1 13.9 12.0 7.6 5.4 14.5 3.6 2.7 7.4 7.4 4.3 5.9 6.8 4.6 3.9 4.7 2.7 5.1 3.8 7.7 4.9 0.0 4.1 0.4 8.0 7.2 6.4 6.3 5.9 8.0 12.7 5.7 4.3 4.9 0.3 6.5 6.4 5.0 6.6 4.3 9.9 12.8 10.7 20.4 8.3 8.6 10.9 7.8 15.0 11.5 6.0 6.4 9.5 3.4 3.8 7.2 8.1 10.2 4.0 4.5 5.2 7.9 34.4 13.3 13.2 10.2 3.2 5.1 0.0 11.2 19.0 5.1 2.3 5.7 8.1 11.2 4.8 10.9 6.2 6.2 42.6 4.4 3.5 3.3 6.4 7.1 2.9 7.8 3.5 4.6 5.6 13.4 0.0 2.1 1.5 7.2 3.6 24.4 6.9 16.6 2.6 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236395 "Enzymes, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 168.1" "Cell type enhanced" "Detected in many" 15 "Cytotrophoblasts: 236.8;Hepatocytes: 188.9;Proximal tubular cells: 112.0" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 27 "basophil: 27.3" "Lineage enriched" "Detected in many" 27 "granulocytes: 27.3" "Cell line enhanced" "Detected in many" "A549: 17.9;HaCaT: 32.2;HL-60: 23.1;OE19: 36.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 6 "hippocampal formation: 2.5" HPA026089 Enhanced NA NA "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 1.1 8.1 0.7 4.1 0.8 1.2 3.4 1.5 1.0 0.5 4.2 0.4 1.3 2.5 0.2 17.5 1.2 2.6 1.3 0.2 1.1 1.1 39.4 168.1 1.7 0.8 0.3 1.0 0.7 6.3 2.0 10.4 7.4 3.0 1.2 4.0 3.2 0.6 0.3 0.2 0.6 5.3 0.1 0.3 0.4 0.4 0.7 0.1 0.1 1.0 0.2 1.3 1.4 0.8 0.1 0.0 27.3 0.0 1.0 0.5 0.2 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.5 9.3 2.5 0.0 0.2 0.4 0.2 32.2 8.2 0.2 0.8 12.6 10.1 13.2 16.6 8.3 0.1 23.1 9.5 0.0 0.7 0.0 0.0 0.0 0.0 6.1 4.0 0.0 0.0 2.9 0.6 15.6 0.6 36.0 0.6 0.0 0.0 0.6 1.7 16.3 14.9 0.9 3.1 0.4 0.0 0.4 1.7 8.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 27.3 0.0 0.4 0.4 0.0 0.4 0.1 0.4 0.4 0.0 0.1 0.1 0.1 0.2 1.0 0.0 0.0 0.5 0.2 0.7 0.8 1.5 1.0 1.1 1.1 0.3 1.0 3.0 0.1 0.0 0.6 0.9 0.8 0.9 0.7 0.3 0.0 54.9 6.8 8.7 0.0 236.8 10.0 0.3 0.4 0.1 20.6 0.0 1.7 2.6 0.0 1.8 5.8 188.9 14.3 1.6 4.1 3.7 2.5 0.0 0.3 0.1 0.0 0.0 18.6 0.5 1.6 28.1 0.0 112.0 1.5 0.0 0.1 1.8 2.5 0.3 45.9 4.3 21.1 4.4 SLC27A5 "ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2" ENSG00000083807 "Solute carrier family 27 member 5" Q9Y2P5 19 58479512-58512413 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Ligase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 157.6" "Group enriched" "Detected in many" 6 "Early spermatids: 114.0;Hepatocytes: 338.0;Late spermatids: 303.5" "Cancer enriched" "Detected in all" 26 "liver cancer: 49.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA007292, CAB056160, CAB068239" Enhanced NA NA "CAB056160: AB_2665590, CAB068239: AB_2665592, HPA007292: AB_1857064" "unprognostic (5.97e-2)" "unprognostic (9.12e-2)" "unprognostic (9.95e-2)" "unprognostic (6.36e-3)" "unprognostic (2.52e-1)" "unprognostic (7.46e-2)" "prognostic favorable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.66e-4)" "unprognostic (2.27e-1)" "unprognostic (3.33e-2)" "unprognostic (7.80e-2)" "unprognostic (2.16e-1)" 1.3 2.0 5.4 1.4 5.3 1.1 2.0 1.9 3.9 1.7 1.0 1.7 1.2 1.0 1.1 1.1 1.4 2.6 1.1 1.3 3.7 3.8 1.9 157.6 0.9 1.4 4.3 2.5 1.4 2.6 1.1 1.3 0.8 3.4 1.4 0.8 1.3 2.7 2.1 1.4 1.1 0.9 1.5 2.7 1.1 1.1 2.3 3.0 1.4 1.8 0.6 1.4 1.1 1.6 13.3 10.8 2.2 3.0 9.6 18.7 8.9 16.0 22.0 3.9 4.1 3.7 3.9 2.4 0.9 2.1 3.1 4.3 1.7 3.5 20.9 2.7 1.1 0.6 3.4 4.5 14.1 1.3 9.7 14.9 14.0 22.9 18.3 5.6 7.3 5.0 4.5 2.4 0.4 8.5 5.3 1.5 15.9 12.9 0.0 3.7 13.1 18.1 15.5 2.4 13.5 12.9 9.1 0.1 28.4 10.1 7.6 5.4 7.3 0.0 21.7 4.7 1.1 6.4 6.4 1.2 0.0 2.8 0.0 1.8 13.8 15.4 8.5 4.5 13.7 0.8 0.0 2.4 2.2 8.7 3.0 18.7 13.3 11.2 11.4 6.5 8.9 13.9 14.3 0.3 9.6 2.1 10.8 13.3 8.9 5.4 5.3 1.9 3.9 3.7 3.8 4.3 2.5 3.4 3.0 0.0 8.2 11.5 13.1 8.0 11.5 5.6 22.9 9.4 5.7 5.2 0.0 6.4 33.2 10.3 114.0 11.9 1.3 0.0 13.3 2.3 7.6 17.0 4.7 338.0 9.1 9.5 9.7 15.4 11.3 303.5 10.0 8.9 15.1 1.8 3.5 6.1 7.4 0.0 8.9 39.7 7.6 6.5 15.5 8.8 13.2 12.3 2.9 10.2 4.7 12.1 SUCLA2 ENSG00000136143 "Succinate-CoA ligase ADP-forming beta subunit" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.0" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 204.8;Late spermatids: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA 6600 Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 21.6 18.5 19.2 8.6 22.1 5.2 17.5 29.7 32.4 15.3 15.7 11.7 15.6 24.5 12.7 12.1 14.6 11.3 9.4 42.1 20.0 21.6 34.0 12.9 7.9 11.4 22.6 19.1 14.4 10.8 19.8 14.9 12.2 28.7 16.2 16.5 8.9 13.9 14.8 89.0 10.0 22.7 14.7 18.3 9.7 12.3 8.0 15.4 15.6 16.9 25.6 10.2 11.0 12.6 17.1 29.5 12.4 25.0 23.4 25.2 17.2 15.7 18.3 23.3 13.9 26.7 20.1 14.0 24.2 27.1 25.2 17.1 32.5 18.0 22.2 18.5 23.6 15.1 22.0 30.7 23.0 31.9 21.2 26.3 24.9 17.4 21.0 18.6 25.1 14.6 19.0 27.1 17.1 20.3 21.0 18.5 25.7 16.8 8.0 25.0 10.9 25.9 28.8 24.1 54.9 23.4 22.1 21.3 17.2 36.4 15.3 12.9 15.4 20.1 18.7 14.2 26.8 16.5 22.4 14.1 14.0 9.0 19.9 16.7 8.4 13.0 25.8 8.7 18.4 20.5 5.7 24.5 12.4 17.6 25.0 21.2 17.1 19.7 21.6 29.5 16.3 25.2 24.9 4.5 23.4 20.0 24.3 21.6 17.2 19.2 22.1 29.7 32.4 20.0 21.6 22.6 19.1 28.7 15.4 23.8 12.6 14.3 29.8 28.7 43.5 135.6 17.8 20.1 17.0 29.6 11.8 41.8 139.3 28.6 204.8 21.5 31.6 0.0 15.6 35.7 34.0 31.8 33.4 11.5 26.3 42.9 18.5 18.4 16.2 235.9 34.2 23.7 40.5 27.9 17.8 38.6 17.5 36.8 43.5 98.7 33.0 38.8 40.8 31.2 27.2 27.7 43.6 13.1 28.8 31.9 SUCLG1 ENSG00000163541 "Succinate-CoA ligase alpha subunit" P53597 2 84423523-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.6" "Cell type enhanced" "Detected in all" 10 "Distal tubular cells: 792.5;Proximal tubular cells: 1327.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 330000 Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 26.1 23.3 18.0 15.0 18.9 10.6 23.8 18.9 19.5 14.1 50.1 17.7 23.2 53.9 13.9 19.6 25.0 13.5 14.0 57.7 17.4 17.3 125.6 44.1 12.8 13.3 19.2 17.0 12.7 33.9 36.2 16.3 13.8 17.3 17.1 39.4 16.9 39.3 24.9 57.6 15.6 71.6 26.5 17.1 12.1 21.9 13.3 16.0 16.9 28.8 42.8 15.2 24.3 16.3 26.6 43.5 31.6 40.3 35.2 39.1 46.8 20.8 23.0 18.2 22.1 34.2 23.1 31.5 23.8 20.4 30.7 22.5 52.6 17.3 28.8 16.5 28.5 24.7 30.5 37.4 28.1 36.5 27.7 34.0 25.0 19.8 29.9 29.0 25.4 20.4 27.4 23.0 25.9 35.3 18.8 27.3 23.6 25.3 23.7 27.9 31.9 36.0 23.2 9.5 78.5 41.2 22.9 42.2 31.5 41.2 25.4 22.1 12.3 19.0 39.5 37.9 17.8 24.1 20.0 22.1 24.1 23.4 29.5 29.2 20.8 29.5 24.8 28.2 35.3 21.2 31.6 34.4 28.7 31.4 40.3 34.6 26.6 29.2 35.1 43.5 20.2 32.4 34.2 18.5 35.2 40.0 23.7 39.1 46.8 18.0 18.9 18.9 19.5 17.4 17.3 19.2 17.0 17.3 16.0 59.6 67.8 89.4 89.8 31.5 32.1 379.6 132.5 91.0 108.1 134.3 21.6 202.1 792.5 102.4 24.5 56.3 282.3 23.3 99.5 100.2 83.9 68.7 90.0 177.6 116.1 42.9 102.0 59.5 64.6 28.6 50.6 82.9 113.1 78.5 140.8 56.0 65.8 217.5 69.6 1327.5 31.0 51.8 72.6 79.7 46.4 36.1 157.6 70.5 304.8 88.9 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming beta subunit" Q96I99 3 67360460-67654614 "Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.9" "Cell type enhanced" "Detected in all" 4 "Hepatocytes: 290.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 290000 Mitochondria "Plasma membrane" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favorable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favorable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 17.0 19.3 8.8 26.5 10.0 3.4 12.4 2.4 7.2 15.3 38.9 9.5 16.4 31.4 11.5 18.3 18.6 9.9 27.9 23.6 6.6 6.2 38.3 90.9 14.6 21.1 9.8 6.5 16.5 20.9 5.9 8.5 8.5 7.6 14.0 34.5 9.6 21.0 17.3 57.0 9.3 42.4 23.5 8.6 24.7 25.4 6.5 8.1 9.6 16.4 27.0 16.7 19.9 13.2 19.2 10.2 5.8 18.2 27.1 31.1 18.9 12.8 11.2 11.1 13.5 18.7 32.4 13.5 15.4 22.5 18.1 20.3 12.3 28.7 16.4 5.0 21.6 11.9 6.6 8.6 21.2 23.5 6.9 5.9 14.8 10.1 19.2 24.1 19.5 10.4 24.2 18.5 14.2 32.6 22.5 19.2 12.6 11.3 15.0 39.4 9.0 7.3 6.2 10.4 58.8 6.9 5.1 17.2 24.5 30.7 19.9 2.2 7.5 24.4 28.2 20.3 7.8 21.7 12.5 16.7 18.0 11.9 19.7 18.2 10.3 15.0 11.5 26.5 15.3 21.1 5.8 15.3 5.2 13.8 18.2 16.7 19.2 20.0 17.4 10.2 16.7 31.1 23.7 0.7 27.1 14.8 4.0 18.5 18.9 8.8 10.0 2.4 7.2 6.6 6.2 9.8 6.5 7.6 8.1 32.8 40.3 57.4 34.0 33.0 2.6 146.2 84.1 61.6 42.1 76.8 7.9 46.8 207.2 71.1 2.4 35.8 224.3 46.7 70.7 37.8 47.4 43.6 29.0 290.2 50.0 4.8 55.9 44.8 60.1 4.1 38.3 46.7 40.5 32.5 187.4 22.3 55.1 140.3 44.6 211.1 3.8 32.3 67.3 1.4 6.8 43.2 31.8 55.8 241.0 45.3 TARS ENSG00000113407 "Threonyl-tRNA synthetase" P26639 5 33440696-33469539 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037425 Approved Approved "Actin filaments,Cytosol" NA NA 170000 Cytosol "Actin filaments" "HPA037425: AB_10672279" "prognostic unfavorable (6.14e-5)" "unprognostic (5.13e-2)" "unprognostic (9.04e-2)" "prognostic unfavorable (5.17e-4)" "unprognostic (9.10e-2)" "unprognostic (1.07e-3)" "prognostic unfavorable (9.88e-7)" "unprognostic (1.43e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-3)" "unprognostic (5.97e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (1.37e-1)" "unprognostic (5.15e-2)" "unprognostic (1.18e-1)" "unprognostic (7.25e-2)" 17.4 25.6 10.2 16.0 13.1 19.2 17.7 14.4 17.2 12.7 22.1 12.3 18.7 11.6 18.3 19.7 31.0 12.2 11.9 19.1 10.3 10.9 19.2 57.0 17.2 12.7 17.5 7.8 21.3 27.6 21.3 27.0 18.5 16.8 13.9 24.7 10.8 42.1 15.8 25.1 11.7 21.7 21.2 19.5 18.3 21.2 9.6 15.4 17.6 22.8 27.3 21.2 21.8 21.9 13.1 16.0 14.2 12.6 24.0 15.0 9.7 29.7 24.9 20.9 29.5 13.8 26.2 30.4 33.5 28.4 25.3 28.7 30.4 18.6 11.8 12.2 27.6 41.7 21.3 44.5 33.1 52.3 17.5 16.2 17.2 64.0 17.3 43.0 27.6 18.4 25.0 53.2 34.9 45.2 15.8 27.1 29.6 33.7 31.9 32.4 16.5 21.5 9.5 22.2 27.1 18.5 18.3 37.1 17.4 28.8 23.8 12.3 13.9 31.0 22.7 22.1 19.3 11.9 24.7 14.3 19.9 29.7 15.7 23.5 18.8 37.0 18.5 22.2 36.4 21.6 14.2 11.6 10.5 15.0 12.6 14.1 13.1 12.7 15.0 16.0 11.5 11.6 14.7 1.5 24.0 10.1 8.8 12.1 9.7 10.2 13.1 14.4 17.2 10.3 10.9 17.5 7.8 16.8 15.4 23.8 23.7 38.9 37.6 25.4 23.3 57.6 35.7 26.8 39.8 17.4 17.7 32.0 41.4 75.9 12.6 24.1 36.2 93.5 83.0 34.9 31.7 29.7 61.2 66.0 28.4 42.9 39.5 25.8 26.4 6.0 17.8 26.3 10.1 83.8 30.4 67.9 95.7 33.7 22.6 30.4 36.0 12.9 31.5 24.1 22.1 17.2 43.6 22.4 28.9 37.7 TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487364-150507609 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA028626: AB_10601719" "unprognostic (2.48e-1)" "unprognostic (7.75e-2)" "unprognostic (6.68e-2)" "unprognostic (3.75e-3)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-2)" "unprognostic (2.14e-1)" "unprognostic (9.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (9.23e-2)" "unprognostic (9.29e-3)" "unprognostic (4.19e-2)" "unprognostic (1.14e-2)" "unprognostic (5.55e-2)" 10.7 21.1 16.5 10.5 17.8 9.2 11.3 17.5 21.4 10.2 10.9 14.8 12.9 9.4 10.5 14.7 15.7 13.0 11.8 20.9 18.1 12.3 15.6 26.8 9.1 14.0 15.0 19.7 13.3 11.5 20.4 12.2 9.4 16.5 9.8 12.5 13.3 11.3 10.9 36.0 13.3 10.5 10.9 13.8 15.1 12.4 10.7 16.6 10.6 12.3 12.2 15.7 12.5 10.8 21.5 17.4 20.4 18.6 21.5 20.9 12.2 17.2 14.4 9.7 14.7 11.0 10.1 18.5 8.4 9.2 16.7 16.8 11.7 16.1 25.0 18.6 6.3 11.5 18.0 23.6 19.5 12.8 15.0 20.5 11.8 13.7 11.8 10.9 16.3 18.1 8.9 16.4 12.6 17.2 10.9 10.7 14.0 20.5 17.6 11.6 20.8 13.7 13.3 12.0 23.9 21.5 14.2 12.4 30.9 11.3 8.1 13.8 16.2 12.7 28.2 19.8 14.4 22.7 25.5 6.3 9.7 10.4 8.0 14.1 17.0 20.0 18.8 14.5 19.0 9.4 15.1 11.0 20.4 15.7 18.3 15.6 21.5 15.4 15.5 17.4 18.6 15.1 15.8 1.7 21.5 18.6 11.7 20.9 12.2 16.5 17.8 17.5 21.4 18.1 12.3 15.0 19.7 16.5 16.6 3.0 13.8 7.2 4.6 3.0 15.8 19.0 12.7 10.7 12.5 7.0 19.6 21.6 10.0 9.9 0.9 6.3 6.6 0.0 8.6 11.4 6.0 3.8 21.9 15.3 11.8 14.3 4.1 7.4 6.5 2.1 7.8 8.0 3.3 16.2 8.9 8.4 9.9 0.0 6.7 6.3 15.4 6.5 7.2 15.4 11.1 3.4 11.8 7.0 10.8 4.1 TARSL2 FLJ25005 ENSG00000185418 "Threonyl-tRNA synthetase like 2" A2RTX5 15 101653598-101724604 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 47.7" "Cell type enhanced" "Detected in many" 5 "Rod photoreceptor cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 9.7;NK-cells: 9.0;T-cells: 6.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066697 Enhanced Approved Cytosol NA NA Cytosol "HPA066697: AB_2685705" "unprognostic (9.33e-3)" "unprognostic (2.13e-2)" "unprognostic (1.88e-1)" "unprognostic (2.54e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (8.45e-2)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-2)" "unprognostic (2.26e-3)" "unprognostic (9.76e-3)" "unprognostic (4.00e-2)" "unprognostic (2.23e-1)" "unprognostic (7.52e-2)" "unprognostic (6.48e-3)" "unprognostic (2.79e-2)" 7.4 6.9 15.1 6.4 20.2 4.8 7.5 15.8 16.2 7.2 7.1 20.2 5.5 6.2 6.5 6.0 6.3 6.5 5.9 21.0 16.9 13.8 8.3 5.9 6.2 6.5 20.0 11.2 11.0 9.8 12.9 10.5 3.7 15.7 9.2 6.2 4.0 7.1 9.7 47.7 4.9 6.5 6.9 19.9 6.2 8.5 5.4 18.9 3.9 9.6 8.0 7.1 7.0 7.8 9.7 2.0 1.6 1.7 9.0 6.1 1.0 2.1 4.0 6.9 3.7 7.4 5.8 3.5 7.4 4.9 5.8 3.6 5.9 1.9 2.8 2.9 8.9 4.7 6.3 12.1 4.3 5.4 3.2 19.5 6.9 2.6 4.6 3.4 3.1 1.4 4.1 4.0 2.7 3.4 6.9 4.1 6.1 6.7 6.1 5.7 3.5 1.7 6.1 8.4 10.6 2.8 3.5 10.5 7.2 4.8 2.1 11.0 6.8 10.0 3.9 4.0 13.3 2.5 6.3 5.5 2.8 6.6 5.6 2.4 8.5 9.5 3.5 7.3 5.6 5.1 0.9 1.1 1.6 3.4 1.7 3.4 4.8 6.1 5.2 0.8 9.7 5.9 3.2 0.3 9.0 0.7 2.0 1.0 1.0 15.1 20.2 15.8 16.2 16.9 13.8 20.0 11.2 15.7 18.9 0.0 5.6 26.9 18.3 16.1 51.2 37.0 5.1 12.0 11.4 5.2 41.2 2.7 16.6 7.6 13.2 12.5 18.0 0.0 10.8 4.0 18.6 13.9 24.3 14.7 4.6 30.2 23.6 8.0 8.9 5.7 21.9 8.6 10.1 9.0 13.5 34.6 17.6 9.3 17.7 17.7 78.2 19.4 16.7 27.4 21.3 10.3 3.5 31.7 12.6 7.1 TRIM25 "EFP, RNF147, ZNF147" ENSG00000121060 "Tripartite motif containing 25" Q14258 17 56887909-56914038 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Ligase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 20.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 20.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005909 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 35000 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA005909: AB_1078722" "unprognostic (8.73e-3)" "unprognostic (1.57e-2)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (2.69e-1)" "unprognostic (3.78e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (1.53e-1)" "unprognostic (4.23e-1)" "unprognostic (1.15e-1)" "prognostic favorable (3.36e-4)" "unprognostic (3.23e-1)" "unprognostic (3.11e-2)" "prognostic favorable (9.35e-4)" "unprognostic (5.21e-2)" "unprognostic (5.13e-2)" "unprognostic (7.39e-2)" 20.0 19.7 7.5 23.6 8.9 32.6 19.3 11.6 7.8 15.3 22.5 5.0 8.0 15.3 13.4 12.6 17.7 15.3 18.4 8.3 5.8 6.3 10.1 27.0 20.8 15.9 6.7 5.5 13.3 15.3 13.6 11.5 55.0 7.4 12.2 14.3 12.5 14.5 11.5 11.7 23.1 20.7 10.1 5.2 35.8 14.1 12.8 6.5 26.2 11.8 15.1 18.5 10.6 35.9 1.7 2.4 20.0 2.3 0.8 1.5 0.7 28.5 14.2 3.5 11.8 26.5 22.4 0.0 11.3 22.9 27.1 23.3 13.8 15.7 27.9 23.5 10.8 29.6 17.0 17.0 15.2 15.2 23.8 13.5 18.0 11.0 15.3 22.7 21.5 13.0 10.0 25.6 14.1 30.0 12.9 17.9 19.2 4.4 17.1 13.7 19.1 24.0 15.5 2.2 23.7 27.6 17.2 11.7 17.6 15.8 22.6 6.8 6.4 8.9 14.3 26.2 2.3 19.4 17.5 11.9 12.7 9.1 19.5 11.7 9.7 18.5 4.6 12.3 14.8 4.9 3.0 2.3 0.9 0.9 1.9 1.1 1.7 0.8 0.8 2.4 1.4 0.6 0.8 20.0 0.8 1.4 1.7 1.5 0.7 7.5 8.9 11.6 7.8 5.8 6.3 6.7 5.5 7.4 6.5 32.8 17.5 11.5 7.3 16.5 8.7 7.0 12.7 20.1 20.5 8.7 27.5 4.1 0.0 16.7 2.1 22.4 32.6 0.0 18.7 8.3 7.8 14.6 3.5 28.7 12.5 3.2 17.9 28.3 31.6 1.2 8.9 23.3 13.5 5.4 26.1 5.2 26.1 26.4 8.9 6.3 19.2 6.5 6.4 0.3 0.0 26.7 13.3 8.6 21.8 16.6 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482154-112541739 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Erythroid cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA066819: AB_2685728" "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 4.4 4.0 9.9 4.2 11.9 7.1 11.3 5.0 12.5 3.3 4.1 9.2 2.5 3.1 4.6 4.2 5.2 3.2 4.9 10.3 9.4 6.5 3.9 3.3 5.9 4.4 8.1 5.3 3.2 3.8 4.1 2.4 5.3 5.9 3.2 3.9 2.6 3.0 3.7 13.1 6.0 3.2 5.8 5.4 4.0 3.2 3.0 6.5 5.1 4.2 5.2 3.8 4.8 2.9 1.8 1.2 2.7 1.3 1.0 1.3 0.5 3.7 2.9 3.7 8.2 4.4 6.3 1.4 6.4 5.3 6.9 5.9 3.5 1.4 3.5 3.6 5.5 4.5 2.6 6.4 3.3 8.3 2.4 3.6 2.9 4.1 4.4 2.0 4.1 1.5 2.8 2.3 10.0 5.3 3.1 5.8 2.4 4.8 2.8 5.4 1.9 3.6 2.3 3.2 1.1 5.8 3.9 4.1 1.9 2.1 2.9 7.8 5.4 5.0 1.7 8.9 2.5 1.7 2.4 5.8 8.2 6.0 6.4 4.8 1.6 3.1 2.9 9.0 3.1 3.5 2.7 1.3 1.0 1.3 0.8 1.1 0.8 1.0 1.0 0.4 1.8 0.9 1.1 2.4 1.0 1.1 1.2 0.8 0.5 9.9 11.9 5.0 12.5 9.4 6.5 8.1 5.3 5.9 6.5 11.9 8.3 3.7 4.2 18.0 16.4 32.0 5.1 2.7 7.9 12.2 11.8 2.6 0.0 6.0 6.1 13.0 5.0 46.7 8.3 2.1 9.4 5.0 0.0 9.4 10.2 7.9 10.9 20.9 24.8 3.6 2.8 15.5 6.8 10.8 5.5 9.1 8.6 5.8 5.3 4.9 21.2 6.5 9.0 1.9 4.3 15.7 1.0 6.1 5.2 3.7 UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm NA NA 16000000 Nucleoplasm "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" 45.6 63.0 56.0 47.2 50.6 42.0 38.3 58.1 75.7 48.0 39.3 55.9 44.9 36.3 52.9 34.1 59.4 56.0 39.9 48.7 49.5 39.9 51.1 60.0 42.0 48.2 47.7 62.3 57.6 34.9 78.8 55.5 39.1 47.6 40.2 35.5 41.0 47.5 45.7 77.7 56.1 37.9 59.4 35.5 53.4 38.7 36.0 48.6 52.7 65.0 43.9 54.0 39.2 52.7 28.9 30.6 32.6 36.0 25.6 29.0 24.1 46.0 47.9 54.8 83.2 37.5 34.2 24.2 30.7 32.7 44.2 36.0 38.0 35.2 34.4 20.4 61.4 65.4 44.6 68.7 65.3 32.4 28.5 69.8 21.5 53.1 30.5 26.4 36.2 46.5 32.1 34.2 64.2 50.1 31.6 57.8 41.4 23.3 30.9 43.8 58.4 34.1 32.0 58.4 27.9 74.9 39.8 38.3 58.5 35.3 49.7 35.5 26.7 91.4 44.5 20.4 61.4 61.8 22.6 42.2 33.2 38.5 47.7 28.6 21.2 22.0 49.1 34.1 25.9 39.6 17.4 27.0 27.4 29.0 36.0 25.4 28.9 24.0 25.9 30.6 22.0 19.1 23.4 32.6 25.6 32.8 20.8 28.2 24.1 56.0 50.6 58.1 75.7 49.5 39.9 47.7 62.3 47.6 48.6 47.6 32.5 35.6 30.6 29.9 25.4 44.0 71.4 29.4 29.6 78.5 15.7 42.1 29.9 67.7 29.3 28.1 83.5 23.3 78.8 52.0 36.1 52.8 17.4 40.8 53.6 11.1 55.2 46.1 45.1 41.8 39.1 34.8 18.6 66.7 64.2 20.0 108.7 57.9 61.9 49.5 24.4 38.8 40.3 8.8 19.6 36.8 59.5 26.6 52.5 48.1 UBA6 "FLJ10808, UBE1L2" ENSG00000033178 "Ubiquitin like modifier activating enzyme 6" A0AVT1 4 67612652-67701179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Urothelial cells: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037001 Approved Enhanced Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA037001: AB_10672787" "unprognostic (2.52e-1)" "unprognostic (4.89e-2)" "unprognostic (3.97e-3)" "unprognostic (2.81e-1)" "unprognostic (3.67e-2)" "unprognostic (4.92e-2)" "unprognostic (3.55e-3)" "unprognostic (6.06e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-2)" "unprognostic (3.38e-2)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.01e-5)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.05e-3)" 16.8 12.6 14.1 14.1 16.6 22.7 13.0 18.0 16.0 17.0 10.5 14.6 7.0 12.2 16.7 10.0 20.5 9.9 12.4 9.5 12.0 12.0 10.2 16.4 14.5 17.3 18.7 11.2 14.3 10.9 17.4 44.8 18.5 17.7 12.7 13.2 7.5 13.7 10.4 10.1 12.6 15.3 13.4 20.7 16.9 13.9 14.6 18.6 27.1 12.3 13.3 19.9 15.7 19.5 5.6 5.1 9.3 4.0 9.7 5.8 1.9 15.1 8.5 14.1 11.0 7.0 8.2 9.5 31.4 12.3 14.4 16.9 8.9 20.5 19.2 11.2 12.9 14.7 9.0 14.5 15.6 21.8 22.1 4.0 12.3 15.0 8.3 6.0 21.6 9.5 5.9 5.0 18.6 11.3 9.9 12.7 9.9 29.2 11.4 17.0 5.7 22.4 4.9 8.3 10.8 10.3 13.3 28.9 7.1 11.8 17.2 6.9 8.7 17.7 12.6 5.9 12.3 8.4 5.8 18.3 13.4 15.1 10.8 13.7 8.2 6.4 19.4 23.8 6.0 12.8 9.3 3.0 4.6 4.4 3.9 4.8 5.6 5.1 5.8 3.7 5.2 3.9 4.5 2.2 9.7 4.0 5.1 4.2 1.9 14.1 16.6 18.0 16.0 12.0 12.0 18.7 11.2 17.7 18.6 23.8 20.8 33.8 52.9 62.3 46.2 14.4 12.7 25.4 20.5 15.7 51.1 22.4 3.3 21.4 1.4 34.4 21.2 0.0 14.8 12.9 28.2 64.5 30.1 17.3 20.5 31.8 31.0 17.8 27.9 4.0 19.8 35.3 23.6 33.3 24.7 19.8 36.7 21.0 18.7 10.2 42.3 19.4 23.0 37.9 35.1 40.4 49.2 29.9 19.6 126.8 VARS VARS2 ENSG00000204394 "Valyl-tRNA synthetase" P26640 6 31777518-31795953 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 205.7;Late spermatids: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.2;U-266/84: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046710 Approved Enhanced Cytosol NA NA 23000 Cytosol "HPA046710: AB_2679765" "unprognostic (1.86e-2)" "prognostic unfavorable (7.25e-4)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.86e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (3.20e-1)" "unprognostic (2.76e-1)" "unprognostic (4.72e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.85e-2)" "unprognostic (2.59e-1)" 11.7 11.4 8.9 12.0 9.5 9.1 18.3 7.6 14.0 8.1 11.3 7.3 5.0 12.8 13.5 6.7 14.2 10.2 8.1 9.5 6.4 6.8 9.5 22.7 11.5 24.2 8.3 9.7 9.6 19.2 15.6 15.0 8.5 8.6 7.7 9.4 6.1 9.1 5.9 30.6 14.3 10.3 13.2 8.7 14.4 15.2 40.6 7.5 10.9 8.2 13.2 11.8 9.7 8.5 1.6 1.5 0.6 1.2 2.4 1.0 0.9 2.2 2.0 3.2 6.4 3.6 2.8 8.7 8.8 2.7 6.6 4.0 2.6 1.4 7.7 10.9 5.5 5.0 2.4 10.2 6.7 4.0 5.6 14.4 3.8 5.1 6.1 4.7 15.3 12.6 4.2 2.4 2.6 6.1 1.9 3.3 3.5 10.6 10.5 4.2 3.5 6.9 0.7 6.1 3.2 4.3 9.0 1.7 25.2 5.1 2.9 3.9 1.5 0.7 8.6 3.7 2.2 5.2 6.1 1.1 4.6 4.2 6.1 14.5 15.0 25.9 6.3 3.3 3.1 5.1 0.0 0.6 0.6 1.0 1.2 1.0 1.6 0.6 0.4 1.1 1.1 0.8 0.8 0.0 2.4 1.0 1.5 0.6 0.9 8.9 9.5 7.6 14.0 6.4 6.8 8.3 9.7 8.6 7.5 6.0 8.2 11.1 8.3 7.3 7.0 7.8 7.6 8.1 9.1 15.7 5.9 19.8 8.3 30.5 205.7 9.2 18.8 23.3 36.1 40.7 10.4 7.3 9.2 21.9 26.7 1.6 22.5 6.2 9.2 188.8 19.2 12.0 6.8 10.0 12.5 7.2 28.7 5.8 12.7 11.4 12.4 19.4 8.1 24.4 29.8 11.3 13.8 6.9 19.2 7.0 VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30908242-30926459 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria NA NA Mitochondria "HPA062449: AB_2684766, HPA070267: AB_2686245" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "unprognostic (1.96e-3)" "unprognostic (2.50e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.23e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-3)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.19e-2)" "unprognostic (2.43e-2)" 7.2 7.8 6.3 12.5 8.6 6.9 6.8 21.4 11.4 4.2 6.5 8.9 6.2 6.2 8.8 6.2 20.6 6.3 7.4 4.9 7.4 6.4 12.0 13.5 7.3 12.9 5.6 9.3 8.8 12.5 8.5 9.7 5.1 7.9 6.0 8.1 4.6 8.2 10.5 9.4 11.0 7.4 4.4 6.3 7.8 8.6 8.3 3.4 13.4 8.2 4.6 10.0 4.8 6.1 1.8 1.3 0.1 0.9 0.2 1.8 0.5 8.6 6.9 3.7 14.8 3.1 2.3 0.1 1.2 0.8 1.2 1.1 6.0 4.9 6.5 5.1 0.9 3.4 0.0 10.4 0.0 1.9 3.4 8.9 7.8 5.8 0.6 2.7 1.6 0.0 1.8 2.6 3.7 0.8 0.4 0.9 11.0 0.0 7.4 3.0 0.0 2.5 0.0 0.9 0.0 0.9 6.1 0.0 6.3 4.9 0.0 4.5 0.1 0.0 3.3 3.7 3.2 10.1 4.1 1.6 9.2 0.6 0.5 0.1 6.8 10.5 13.5 0.0 0.3 6.1 0.0 0.2 0.0 1.1 0.9 1.8 1.8 1.0 1.6 1.0 0.7 0.6 0.3 0.1 0.2 0.6 1.3 1.2 0.5 6.3 8.6 21.4 11.4 7.4 6.4 5.6 9.3 7.9 3.4 6.0 15.1 9.3 4.8 3.5 6.2 11.0 10.2 6.7 4.5 8.7 0.0 7.5 1.7 5.3 1.2 3.8 10.5 0.0 6.1 9.2 3.5 2.0 12.7 19.2 8.2 7.9 12.6 8.6 7.5 0.5 3.7 4.9 1.7 8.2 7.2 2.9 6.7 5.9 3.9 10.7 5.7 0.0 3.4 9.1 8.1 3.6 2.9 7.5 8.6 3.3 WARS "IFI53, IFP53" ENSG00000140105 "Tryptophanyl-tRNA synthetase" P23381 14 100333788-100376805 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 142.8;thyroid gland: 157.0" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 112.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "intermediate monocyte: 131.2;non-classical monocyte: 142.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 118.8;SK-MEL-30: 143.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 53000000 Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 42.5 23.3 14.5 53.9 20.1 17.0 20.6 10.7 25.4 11.1 19.1 13.3 7.1 12.7 16.5 20.5 17.8 14.5 13.7 32.0 17.8 18.7 24.6 17.9 68.5 35.3 16.9 14.8 12.1 15.6 9.4 23.5 89.6 28.2 16.4 21.0 23.5 15.7 11.7 22.3 9.3 19.8 21.0 15.7 51.6 19.8 23.7 9.4 20.9 157.0 19.2 22.7 24.0 13.8 5.6 27.7 51.8 142.8 3.3 3.4 46.4 11.1 10.6 7.0 40.7 10.1 14.4 11.2 14.4 27.9 31.0 39.2 6.9 10.0 12.1 13.5 34.3 7.6 19.0 20.2 16.4 20.0 19.2 5.8 7.8 8.1 8.5 118.8 22.2 12.8 16.3 23.6 18.0 37.5 9.4 27.8 8.2 24.4 32.1 13.2 21.3 7.6 10.4 7.0 11.4 19.3 6.4 11.0 7.7 15.1 9.8 18.7 10.9 8.6 7.5 143.4 9.4 19.1 28.2 18.4 3.3 7.5 33.9 7.5 62.6 31.8 22.5 37.4 17.3 30.2 6.1 39.5 51.8 3.4 131.2 3.1 5.6 2.8 3.1 27.7 4.1 2.0 2.4 14.1 3.3 142.8 4.2 3.3 46.4 14.5 20.1 10.7 25.4 17.8 18.7 16.9 14.8 28.2 9.4 23.8 39.7 41.6 6.7 12.9 9.0 12.1 7.6 30.8 29.6 21.0 19.6 14.6 13.3 29.0 112.5 76.4 8.5 0.0 56.4 9.8 20.5 12.1 29.0 14.9 40.6 7.9 14.3 87.8 44.2 82.6 10.6 72.8 8.5 71.3 14.1 9.3 34.3 7.2 12.7 15.3 15.8 19.4 21.7 69.3 20.9 10.7 13.8 10.2 10.1 11.4 WARS2 TrpRS ENSG00000116874 "Tryptophanyl tRNA synthetase 2, mitochondrial" Q9UGM6 1 119031216-119140671 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 52.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028007, HPA069692" Enhanced Supported Mitochondria NA NA Mitochondria "HPA028007: , HPA069692: AB_2686172" "unprognostic (1.00e-1)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (5.64e-2)" "unprognostic (3.42e-1)" "unprognostic (7.05e-2)" "unprognostic (7.73e-3)" "unprognostic (3.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.17e-2)" "unprognostic (3.96e-2)" "unprognostic (6.76e-3)" "prognostic favorable (1.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.83e-1)" "unprognostic (9.88e-3)" "unprognostic (4.71e-2)" 17.3 16.7 6.8 11.7 8.3 2.8 14.6 7.5 8.7 12.9 11.2 7.7 7.6 12.3 13.5 10.4 13.4 14.9 8.8 12.1 6.2 6.1 15.3 14.9 9.2 12.4 6.4 6.1 14.7 17.8 15.1 12.3 14.9 8.3 14.1 12.7 11.3 10.5 10.4 12.2 10.0 13.1 9.0 5.4 9.9 11.2 6.9 6.1 11.6 12.8 13.2 14.2 14.3 10.4 7.2 9.0 0.5 6.9 5.3 7.4 4.9 10.3 4.5 6.1 6.4 7.8 17.6 6.6 5.8 8.3 6.1 7.3 11.3 4.7 15.2 9.5 9.3 3.7 7.0 10.9 9.9 9.4 8.2 14.2 7.2 12.1 10.8 15.9 11.6 4.1 13.4 7.7 8.9 16.3 8.1 9.1 6.7 11.2 11.1 11.3 12.0 6.9 6.7 8.2 7.8 9.3 5.1 20.2 7.7 16.7 14.5 9.0 5.5 9.1 12.7 13.1 11.2 5.6 9.1 6.9 6.7 8.0 12.5 11.0 5.4 3.6 6.7 8.2 9.8 12.3 0.0 6.9 0.5 5.1 4.9 7.4 6.6 5.4 6.7 9.0 7.2 6.5 6.2 0.3 5.3 3.0 4.5 6.0 4.9 6.8 8.3 7.5 8.7 6.2 6.1 6.4 6.1 8.3 6.1 8.9 10.5 8.8 16.5 8.5 6.3 9.2 7.6 16.0 10.3 10.4 5.9 14.1 14.9 9.0 52.2 6.8 5.2 0.0 10.3 13.0 10.8 11.7 8.1 7.3 8.4 6.4 6.4 1.8 7.3 24.7 9.2 6.3 10.1 15.4 9.5 4.9 9.1 3.5 7.8 12.6 7.7 6.5 9.5 3.5 5.9 9.4 16.7 6.4 14.6 11.3 YARS "tyrRS, YRS, YTS" ENSG00000134684 "Tyrosyl-tRNA synthetase" P54577 1 32775237-32818153 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017936, HPA018950, HPA018954" Enhanced Enhanced Cytosol No No 230000 Cytosol "HPA017936: AB_1858916, HPA018950: AB_1858919, HPA018954: AB_1858915" "unprognostic (4.05e-2)" "unprognostic (2.52e-1)" "unprognostic (4.21e-1)" "unprognostic (4.78e-2)" "unprognostic (9.54e-2)" "unprognostic (3.38e-3)" "prognostic unfavorable (6.97e-11)" "unprognostic (5.05e-2)" "unprognostic (6.29e-2)" "unprognostic (1.93e-1)" "unprognostic (1.81e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (1.02e-11)" "unprognostic (3.57e-3)" "unprognostic (1.02e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (6.57e-4)" 16.6 36.3 22.8 22.8 40.6 17.4 13.9 26.6 43.1 14.6 17.5 16.3 22.4 17.1 14.2 15.5 24.1 14.4 11.2 15.5 24.9 28.3 14.1 29.6 21.3 23.2 24.9 27.4 21.2 54.8 19.3 13.9 17.5 26.7 12.7 21.9 11.2 23.5 25.7 27.3 16.5 14.9 22.7 22.7 14.6 25.9 20.9 26.0 15.2 30.0 16.8 29.6 17.0 28.0 9.9 17.8 20.9 13.4 36.5 24.3 17.1 28.8 15.1 15.9 38.3 19.8 22.8 17.0 29.8 24.7 24.5 31.3 17.9 19.9 52.5 11.8 30.9 20.0 17.0 48.4 35.1 38.8 22.1 19.2 48.1 22.9 16.8 65.2 37.9 29.1 22.6 43.7 38.7 98.6 17.7 24.8 42.5 52.9 55.6 21.0 14.9 42.5 20.8 29.0 29.5 20.9 37.2 15.2 44.1 17.6 14.5 30.7 18.9 16.2 19.1 55.0 19.0 19.1 41.3 20.1 14.9 26.6 30.2 24.6 44.9 47.9 49.1 37.3 52.9 40.9 20.9 12.7 6.6 24.3 13.4 23.9 9.9 14.5 22.3 17.8 8.1 10.8 16.5 3.0 36.5 12.4 10.2 15.6 17.1 22.8 40.6 26.6 43.1 24.9 28.3 24.9 27.4 26.7 26.0 20.8 45.6 14.5 22.1 22.2 19.3 14.9 5.1 34.8 34.2 8.7 25.5 36.7 3.3 30.4 14.4 19.0 12.8 0.0 71.3 38.8 20.0 22.9 12.8 23.3 35.7 30.2 16.7 7.4 22.2 12.4 11.8 21.1 13.5 35.1 12.7 10.8 50.1 3.5 10.6 9.8 19.8 12.9 24.5 26.7 19.4 21.3 31.5 33.0 17.5 30.1 YARS2 "CGI-04, FLJ13995, mt-TyrRS" ENSG00000139131 "Tyrosyl-tRNA synthetase 2" Q9Y2Z4 12 32727490-32755902 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038721, HPA057610, HPA074097" Uncertain Supported "Nuclear bodies,Mitochondria" NA NA Mitochondria "Nuclear bodies" "HPA038721: AB_10674837, HPA057610: AB_2683483, HPA074097: AB_2686660" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-3)" "unprognostic (1.02e-2)" "unprognostic (2.12e-1)" "unprognostic (5.99e-3)" "prognostic unfavorable (3.19e-5)" "unprognostic (1.41e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-2)" "unprognostic (8.39e-2)" "unprognostic (7.45e-2)" "unprognostic (1.99e-1)" "unprognostic (4.71e-1)" "unprognostic (4.07e-1)" "unprognostic (2.09e-1)" 12.6 15.8 11.0 12.6 15.3 13.9 13.8 11.6 14.9 13.1 11.8 11.5 18.4 9.8 13.3 12.9 17.5 11.3 9.1 12.1 11.9 9.7 12.4 16.3 9.2 15.5 10.8 11.7 13.3 21.0 11.0 16.6 15.9 13.5 12.9 13.7 11.3 17.4 10.0 15.9 12.0 10.8 11.1 12.6 13.3 12.3 12.5 12.6 17.5 12.3 16.0 16.4 13.3 11.8 11.8 9.5 9.4 9.9 12.9 12.7 5.2 9.4 11.4 6.7 7.9 7.3 8.6 21.0 7.2 7.4 9.0 8.8 28.5 12.1 17.1 11.9 7.3 13.0 12.3 13.2 19.1 10.2 7.4 20.7 11.3 8.6 15.8 10.6 12.0 6.6 8.0 12.2 8.5 15.5 11.6 14.2 9.1 15.9 7.9 9.4 7.7 8.9 14.5 36.6 6.3 14.0 10.1 14.2 10.1 11.4 13.6 10.3 5.0 11.1 9.7 7.1 27.1 18.1 10.9 9.5 8.5 9.0 13.8 12.2 4.7 5.0 17.8 7.9 9.0 7.0 9.4 7.0 4.1 10.1 8.9 10.6 8.8 10.7 10.4 9.5 11.8 11.2 12.7 1.4 12.9 9.9 9.3 9.3 5.2 11.0 15.3 11.6 14.9 11.9 9.7 10.8 11.7 13.5 12.6 6.0 4.1 13.7 17.3 9.0 16.5 6.9 2.5 5.3 7.9 10.4 19.6 29.4 6.6 17.0 4.4 5.7 5.2 23.3 14.2 29.0 10.7 7.9 6.9 4.5 17.9 14.3 6.9 5.5 7.0 2.8 9.8 5.5 5.0 19.0 6.6 11.6 12.2 10.4 8.1 9.3 18.8 12.9 6.2 4.9 14.7 7.3 15.0 12.1 11.5 11.4