Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 30.2" "Cell type enhanced" "Detected in some" 12 "Basal glandular cells: 1.6;Glandular cells: 2.0;Pancreatic endocrine cells: 3.6;Spermatogonia: 1.5;Suprabasal keratinocytes: 1.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.9" "Group enriched" "Detected in many" 8 "basal ganglia: 1.1;cerebellum: 1.4;cerebral cortex: 2.3;pons and medulla: 1.1" "Group enriched" "Detected in some" 5 "gdT-cell: 1.0;naive CD4 T-cell: 2.7" "Lineage enriched" "Detected in single" 28 "T-cells: 2.7" "Cell line enhanced" "Detected in some" "A-431: 6.6;HBEC3-KT: 10.8;hTCEpi: 8.0;hTERT-HME1: 15.1;T-47d: 4.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.1 0.0 0.1 0.1 1.1 0.0 1.6 1.4 2.3 1.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 1.1 0.1 0.0 0.1 0.1 0.1 0.1 30.2 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 1.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 2.7 0.2 6.6 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.4 0.1 0.5 0.2 0.2 0.1 3.2 0.5 0.9 10.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.0 0.2 15.1 0.0 0.0 1.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.8 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.1 1.4 2.3 0.1 0.1 0.1 0.1 1.1 0.1 0.0 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.9 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.5 1.6 0.9 0.0 0.0 0.7 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986178-34008108 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.0;liver: 63.6" "Cell type enhanced" "Detected in many" 10 "Hepatocytes: 17.8;Late spermatids: 18.9;Proximal tubular cells: 33.2" "Cancer enhanced" "Detected in all" "prostate cancer: 34.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 59.8;U-266/84: 31.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 65000 "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 2.8 8.3 5.2 2.7 8.2 0.9 2.8 4.7 7.8 4.4 14.1 4.3 6.5 6.2 4.0 3.6 8.2 2.3 11.0 3.5 4.5 6.8 68.0 63.6 3.3 2.0 4.5 4.5 2.9 5.1 5.4 4.3 3.2 7.0 13.9 15.5 5.5 25.4 5.4 6.0 2.6 7.4 3.7 3.8 2.9 15.9 2.1 2.1 3.8 3.3 3.4 3.3 5.7 4.5 7.8 10.2 11.2 14.2 9.9 10.0 6.8 4.1 6.6 3.7 4.8 2.6 4.1 6.4 5.5 4.1 2.5 1.9 21.6 5.0 1.3 2.9 7.8 9.7 1.9 0.9 4.0 2.6 4.1 3.5 3.1 4.8 6.2 1.8 1.9 1.0 6.2 2.0 3.3 1.2 3.6 2.8 2.7 1.2 4.9 7.5 3.0 1.6 2.4 3.3 3.0 10.8 1.9 6.3 2.1 11.3 20.7 2.1 2.9 9.1 6.5 5.5 3.2 5.0 1.9 5.2 8.4 1.9 2.1 4.4 59.8 31.1 2.4 2.4 3.9 6.2 0.3 7.1 10.2 10.0 8.8 8.4 7.8 8.7 7.8 10.2 7.0 8.1 6.1 11.2 9.9 14.2 5.3 8.9 6.8 5.2 8.2 4.7 7.8 4.5 6.8 4.5 4.5 7.0 2.1 3.0 2.6 0.0 0.4 0.3 3.3 0.9 7.6 4.0 5.7 1.8 0.0 0.9 5.0 0.7 8.1 0.8 5.0 0.0 3.3 0.9 1.1 0.6 0.0 17.8 0.9 4.8 4.1 1.3 1.2 18.9 0.6 0.8 0.0 1.8 4.5 10.6 2.4 3.5 2.1 33.2 0.8 0.0 0.5 0.7 0.7 0.5 0.2 0.8 4.0 0.3 BPGM ENSG00000172331 "Bisphosphoglycerate mutase" P07738 7 134646808-134679813 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Congenital erythrocytosis, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "placenta: 184.7" "Group enriched" "Detected in all" 5 "Distal tubular cells: 109.5;Erythroid cells: 303.7;Syncytiotrophoblasts: 308.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 38.0;RT4: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016493, HPA028735" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 69000000 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA016493: AB_1845414, HPA028735: AB_10600791" "unprognostic (2.56e-1)" "prognostic favorable (7.95e-4)" "unprognostic (3.19e-1)" "unprognostic (3.94e-1)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (3.81e-3)" "unprognostic (1.96e-1)" "unprognostic (7.74e-2)" "unprognostic (4.67e-3)" "unprognostic (7.42e-2)" "unprognostic (5.69e-2)" "prognostic favorable (1.54e-8)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.78e-2)" 6.1 7.3 13.6 4.5 11.1 37.7 6.9 11.7 11.6 7.1 6.9 9.1 6.1 4.3 5.4 10.2 14.6 4.7 6.9 7.3 12.5 14.2 19.1 8.1 8.0 5.2 13.9 7.8 5.7 5.4 16.5 14.4 184.7 12.4 7.5 5.4 6.7 10.6 10.3 17.7 5.5 6.0 6.6 15.9 8.6 6.8 7.4 8.8 8.5 7.5 22.2 13.3 24.9 9.5 11.6 10.2 28.2 12.8 9.8 14.5 12.8 4.5 5.5 7.4 9.9 8.5 5.0 7.4 13.7 16.6 5.3 8.0 2.2 6.1 5.5 4.1 7.6 10.6 3.7 7.8 7.5 9.4 38.0 6.8 3.2 5.1 2.5 5.8 6.0 4.2 4.9 6.9 10.0 5.5 8.2 19.3 7.0 9.2 7.0 12.6 2.2 9.8 8.4 7.6 9.3 5.3 7.5 5.3 4.0 12.1 61.1 6.3 10.7 6.3 7.7 6.8 8.2 5.1 3.9 14.7 8.5 2.0 11.4 11.1 11.5 13.2 6.9 14.7 5.8 14.5 28.2 9.8 27.6 14.5 12.8 10.4 11.6 9.5 12.7 10.2 10.5 13.2 13.4 18.0 9.8 12.5 6.7 12.0 12.8 13.6 11.1 11.7 11.6 12.5 14.2 13.9 7.8 12.4 8.8 8.9 26.7 14.4 18.4 34.7 20.3 20.5 15.3 29.4 14.8 26.2 2.0 35.3 109.5 38.4 2.2 11.9 5.1 303.7 15.9 28.0 17.1 21.1 24.3 4.3 13.3 19.1 12.6 8.0 7.3 5.1 9.5 11.3 21.9 19.8 3.8 18.6 36.1 3.5 11.3 47.1 11.6 6.5 24.7 27.9 22.5 11.5 308.5 21.5 4.5 13.7 CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated protein homolog" Q6UX04 5 64768930-65018763 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Dwarfism, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Early spermatids: 197.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "HPA020344: AB_1856644, HPA024149: AB_1856645, HPA065809: AB_2685561" "unprognostic (1.71e-1)" "unprognostic (6.47e-3)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (5.27e-6)" "unprognostic (1.58e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (7.45e-3)" 15.6 16.4 22.0 14.9 30.4 21.7 16.4 30.1 25.6 16.5 17.5 13.8 14.0 11.8 19.4 15.7 17.3 14.9 13.8 22.1 20.6 19.9 17.5 12.1 12.8 17.0 22.3 20.7 23.3 10.9 21.4 28.8 17.5 26.2 18.6 18.7 11.4 13.3 16.0 24.0 13.8 15.9 24.7 23.3 15.0 13.9 19.6 23.6 22.5 17.2 18.2 18.6 18.6 20.0 15.1 14.6 8.6 11.5 17.0 15.9 9.0 15.2 10.2 18.4 34.0 15.8 19.3 20.5 16.1 13.4 18.0 19.0 17.0 19.4 22.7 28.2 16.7 20.3 9.7 19.2 29.1 32.9 18.9 15.7 17.0 17.2 14.1 24.2 17.8 11.6 12.8 22.4 22.7 28.9 16.0 19.0 26.0 16.5 15.0 17.8 15.2 24.7 16.1 14.9 8.0 12.4 23.0 24.7 23.6 17.1 13.3 21.9 9.7 19.6 8.0 18.1 18.3 17.4 26.2 15.8 10.6 18.7 16.9 25.6 11.7 15.2 22.3 19.9 31.3 18.8 8.6 11.5 7.9 12.8 11.3 15.5 15.1 14.2 15.9 14.6 11.9 15.4 15.9 2.5 17.0 8.5 12.0 15.1 9.0 22.0 30.4 30.1 25.6 20.6 19.9 22.3 20.7 26.2 23.6 8.9 25.8 20.1 22.0 14.5 30.0 55.8 20.4 33.5 14.8 14.0 13.7 36.6 18.3 35.9 197.3 26.9 10.5 23.3 28.8 45.9 24.6 20.8 18.5 10.5 28.6 19.1 28.7 14.1 17.2 37.1 35.6 23.8 13.5 29.7 16.0 31.3 33.5 10.5 33.9 21.9 53.9 32.3 28.4 43.0 28.9 17.6 25.7 23.6 26.6 17.4 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436808-94479682 "Enzymes, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 58 "retina: 151.5;skin 1: 54.2" "Cell type enriched" "Detected in some" 25 "Melanocytes: 3369.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 259 "SK-MEL-30: 76.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.2 0.2 0.5 0.1 1.5 0.1 1.7 0.2 0.6 0.2 0.1 0.3 0.1 0.0 0.2 0.5 0.1 0.8 0.1 0.1 0.4 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.1 1.4 0.1 0.3 0.2 0.0 151.5 1.4 0.2 0.2 54.2 0.2 0.1 0.8 0.1 0.0 0.3 0.4 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.5 0.2 0.6 0.4 0.5 0.3 0.1 0.3 0.4 0.0 0.0 0.0 0.1 135.3 0.7 0.8 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 12.6 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.9 0.0 3369.1 0.0 0.0 2.4 0.0 0.0 0.7 0.0 0.2 0.0 0.9 0.5 0.2 29.2 0.0 0.0 0.0 0.0 DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444860 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 85.3;Macrophages: 81.1;monocytes: 97.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 8.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014764, HPA052151" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA Nucleoplasm Cytosol "HPA014764: AB_1856587, HPA052151: AB_2681746" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" 32.3 10.6 7.4 22.3 10.7 13.1 34.8 5.4 7.7 16.0 12.8 4.9 9.9 5.3 11.7 18.5 13.5 15.3 12.9 16.1 8.1 4.3 11.2 10.4 17.7 13.1 9.8 4.5 21.0 4.0 15.4 20.9 21.7 13.1 13.0 7.1 14.3 9.3 9.4 8.5 16.9 10.7 12.8 16.1 24.9 7.6 10.9 9.0 8.3 8.7 10.9 8.3 14.6 29.4 3.6 8.9 2.5 3.9 0.2 1.1 1.2 10.5 2.3 7.9 7.4 21.5 14.2 9.0 12.5 29.4 15.7 23.1 0.0 3.0 0.3 1.1 21.8 15.8 20.3 1.1 29.4 20.6 10.9 4.8 0.7 3.4 0.1 24.0 0.5 0.5 30.1 12.7 17.4 17.1 8.2 9.2 2.7 0.2 4.8 7.5 0.3 1.4 0.6 4.2 0.0 0.6 1.8 7.3 5.0 10.4 0.7 2.6 2.0 12.1 0.0 0.3 5.7 0.1 1.2 3.4 15.9 4.6 3.9 10.0 1.0 0.3 0.5 8.4 1.3 1.8 0.7 3.1 0.1 1.0 3.9 0.6 3.2 0.9 0.4 8.9 3.6 1.1 0.4 2.5 0.2 2.2 4.2 0.2 1.2 7.4 10.7 5.4 7.7 8.1 4.3 9.8 4.5 13.1 9.0 14.9 2.6 18.6 20.6 46.1 4.1 7.0 5.1 18.7 18.2 3.5 0.0 2.0 6.6 4.0 39.9 11.9 0.0 0.0 7.5 3.7 35.5 14.2 22.0 3.8 39.5 1.6 1.2 57.7 85.3 19.2 50.9 81.1 10.1 97.4 0.7 3.9 9.5 0.0 28.3 6.1 3.0 32.3 29.2 2.6 5.1 34.9 4.1 6.5 1.0 42.4 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "Emopamil binding protein (sterol isomerase)" Q15125 X 48521158-48528716 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease mutation, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.1" "Cell type enhanced" "Detected in all" 7 "Hepatocytes: 389.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 3.7 33.2 5.3 4.3 5.7 10.5 10.5 10.1 6.3 8.6 19.6 2.8 3.4 17.2 4.0 3.7 20.6 3.9 4.5 21.7 4.7 4.3 12.8 74.1 14.9 13.0 3.5 8.0 4.8 11.7 6.0 3.7 4.2 8.8 8.6 15.7 5.2 8.7 4.8 3.5 9.1 30.0 5.6 7.0 7.9 8.1 5.4 2.8 9.0 4.6 9.8 10.4 5.0 10.0 17.1 22.9 21.5 12.6 13.3 29.9 18.1 33.6 7.1 18.9 11.3 10.5 7.8 6.1 8.6 7.2 11.5 16.6 14.1 56.2 18.2 6.1 6.0 11.3 37.9 31.6 46.7 8.7 14.0 15.8 9.2 9.5 12.1 7.7 33.8 22.8 7.6 17.0 15.3 11.4 2.9 7.6 12.9 11.7 17.3 9.4 14.7 18.8 20.7 19.0 9.7 23.4 13.0 1.9 51.6 28.1 6.0 16.1 8.1 31.8 16.4 4.5 12.6 18.0 8.1 8.0 5.9 10.0 22.7 9.4 7.4 11.6 18.4 13.7 34.1 5.6 17.4 8.9 21.5 29.9 11.7 25.1 17.1 22.2 27.5 12.3 12.6 20.1 25.5 1.8 13.3 12.6 22.9 22.4 18.1 5.3 5.7 10.1 6.3 4.7 4.3 3.5 8.0 8.8 2.8 29.8 39.6 41.7 45.2 33.0 23.7 36.3 81.5 22.7 21.6 50.6 7.9 40.6 33.2 80.2 5.4 24.3 135.6 46.7 207.1 93.9 32.6 42.4 40.3 389.0 57.0 7.9 28.8 28.8 26.6 7.8 12.4 34.4 35.4 47.7 72.4 13.4 126.3 129.8 13.8 76.4 15.9 12.9 20.6 8.6 20.0 39.6 31.4 74.7 134.2 61.7 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239395-2252300 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 90.3" "Cell type enhanced" "Detected in many" 5 "Distal tubular cells: 255.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 11000000 Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 15.7 12.5 12.5 9.8 10.8 9.1 16.8 12.8 11.3 10.9 27.6 9.7 20.3 30.9 10.6 16.7 15.5 13.4 17.3 56.4 10.1 10.3 36.5 57.4 10.3 10.7 12.4 8.8 10.8 30.4 11.1 11.9 10.6 13.0 13.4 8.4 16.3 40.9 19.1 90.3 10.4 31.2 14.1 10.1 8.0 17.2 8.4 9.6 10.4 38.7 25.4 10.5 14.4 11.5 7.6 6.5 3.9 7.1 5.8 6.7 1.7 7.3 17.7 6.8 27.8 2.6 3.7 25.5 7.4 5.2 6.2 9.1 31.1 22.7 10.7 18.7 4.6 4.4 18.3 7.9 7.1 0.8 18.5 40.7 3.3 16.5 38.4 23.8 9.6 1.5 6.8 16.8 5.1 11.1 4.4 6.1 0.2 17.7 22.7 2.1 30.4 0.9 14.4 15.7 11.9 17.9 33.6 7.3 51.4 11.7 8.4 23.4 14.8 18.1 34.1 22.5 3.5 22.0 17.1 5.0 4.8 18.1 5.2 8.3 25.2 14.8 17.4 6.3 8.9 6.8 3.2 6.8 2.7 3.8 7.1 6.0 7.6 5.5 2.9 5.5 7.4 6.7 5.6 3.9 5.8 4.2 6.5 6.7 1.7 12.5 10.8 12.8 11.3 10.1 10.3 12.4 8.8 13.0 9.6 3.0 23.3 31.8 94.0 18.9 51.2 90.1 94.3 9.4 14.8 73.3 41.2 151.4 255.4 28.6 6.2 23.5 150.2 0.0 31.7 67.6 25.6 72.7 5.7 199.4 41.4 20.6 43.7 26.4 26.7 4.2 22.7 23.7 37.1 14.4 73.5 52.4 28.1 70.2 22.6 187.7 57.7 0.0 30.2 2.5 15.8 19.4 91.9 17.5 89.4 98.4 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115689-4135597 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.3" "Cell type enhanced" "Detected in all" 8 "Distal tubular cells: 363.1;Proximal tubular cells: 504.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 17.9 29.2 13.2 7.3 17.4 4.5 17.0 8.9 9.5 15.7 18.0 10.7 14.9 16.2 15.2 26.2 10.6 12.7 12.4 32.1 10.3 11.1 56.8 102.3 7.4 8.9 13.3 7.2 19.0 59.2 8.9 17.2 11.1 10.3 14.6 14.0 13.3 9.0 10.5 45.7 5.6 22.7 10.3 11.9 10.1 23.2 11.9 9.3 13.3 17.7 26.6 7.5 12.6 8.9 20.6 25.1 7.0 16.2 25.5 27.7 16.7 17.8 9.7 16.3 35.3 20.5 30.5 2.0 25.3 25.9 27.6 24.7 7.3 2.7 0.7 31.9 27.5 25.1 9.4 18.4 14.7 40.2 6.7 21.1 9.4 13.7 39.3 11.9 8.5 4.7 20.9 9.0 23.5 13.2 37.6 57.5 30.4 30.8 6.9 26.1 7.1 24.0 21.2 11.0 1.7 34.8 23.3 20.2 0.3 14.9 3.6 0.3 7.6 1.5 10.6 22.3 30.8 24.5 4.0 58.0 20.8 11.4 18.4 15.0 10.5 18.8 1.8 10.7 7.5 16.1 6.9 15.5 7.0 18.9 11.5 25.9 19.9 22.3 26.4 25.1 20.6 27.7 27.1 0.4 25.5 16.2 19.2 23.6 16.7 13.2 17.4 8.9 9.5 10.3 11.1 13.3 7.2 10.3 9.3 26.8 25.1 23.1 44.0 16.3 13.3 158.2 86.6 121.8 59.1 34.9 11.8 242.5 363.1 46.4 49.2 44.3 33.7 46.7 154.5 15.1 57.4 23.5 22.0 167.8 55.4 17.5 50.1 41.7 22.4 39.8 58.7 24.7 33.7 36.1 38.2 54.7 71.1 41.2 47.7 504.9 43.8 25.8 23.7 25.7 33.2 11.2 85.2 49.0 60.0 20.4 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 37.1;liver: 91.2" "Group enriched" "Detected in many" 7 "Hepatocytes: 227.5;Proximal tubular cells: 124.0" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 16.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 4.1 1.2 1.2 1.7 1.4 0.1 1.5 0.5 1.2 1.7 6.4 0.8 0.4 5.2 1.0 2.0 2.9 0.8 3.0 3.2 1.2 0.9 37.1 91.2 1.9 1.0 1.7 0.7 0.8 2.5 2.7 0.9 1.3 2.1 1.7 2.6 8.3 2.7 0.4 0.7 1.1 9.9 1.0 1.4 1.7 2.4 0.9 0.9 1.4 2.1 1.7 1.2 1.8 1.0 1.5 6.0 0.2 2.2 2.7 2.7 1.1 8.3 3.5 1.0 0.0 5.3 4.5 1.1 4.0 1.2 2.6 3.0 15.2 5.3 0.0 15.9 4.0 1.0 4.1 0.0 3.3 5.5 11.1 3.7 5.9 0.9 15.4 3.5 0.7 0.1 6.4 4.3 2.7 2.4 3.6 3.8 0.0 3.8 4.3 5.0 4.3 0.1 3.5 2.1 3.0 4.4 0.0 7.1 0.3 11.0 4.7 3.2 4.6 7.8 4.6 7.3 9.1 16.8 6.9 1.8 1.7 2.6 1.3 0.3 1.2 3.8 0.3 0.6 2.6 2.8 0.2 2.2 0.0 1.6 2.1 1.0 1.5 1.1 2.4 6.0 0.2 1.6 2.7 0.1 2.7 2.0 2.4 1.4 1.1 1.2 1.4 0.5 1.2 1.2 0.9 1.7 0.7 2.1 0.9 14.9 7.5 13.7 1.5 1.3 0.2 17.9 25.5 4.0 4.5 19.2 3.9 7.2 16.6 2.0 0.1 2.8 13.8 0.0 5.9 2.1 1.5 1.8 0.0 227.5 3.7 0.0 7.5 12.3 12.4 0.0 0.6 1.3 3.3 15.4 11.6 1.7 3.3 8.6 0.4 124.0 0.9 0.0 2.0 3.9 4.1 0.4 1.1 3.2 10.6 1.6 FKBP10 "FKBP6, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FK506 binding protein 10" Q96AY3 17 41812680-41823217 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Fibroblasts: 83.0;Leydig cells: 43.4;Peritubular cells: 42.1;Sertoli cells: 58.2;Smooth muscle cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "NK-cell: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 72.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 5500 Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 16.9 16.5 6.6 13.2 7.2 0.2 14.9 3.4 8.4 43.0 11.5 6.0 15.8 3.8 42.7 39.0 14.0 21.4 28.6 19.2 5.6 3.6 10.3 3.2 16.2 17.1 5.3 6.7 35.5 13.5 24.7 22.7 33.8 5.2 21.3 5.7 17.1 6.5 17.0 9.6 8.8 7.6 27.9 5.5 7.9 8.5 15.1 5.7 1.2 16.9 9.5 8.1 24.4 19.2 0.3 0.0 0.0 0.0 2.0 0.9 0.1 0.0 16.2 15.0 49.1 52.8 61.7 13.2 66.9 67.0 25.2 21.8 8.4 0.6 0.0 0.9 72.6 6.4 0.1 8.9 17.8 10.7 4.4 13.5 6.4 18.3 24.0 57.7 0.0 0.0 66.2 0.0 20.6 15.8 48.4 21.4 0.0 0.2 2.3 21.0 21.1 0.0 0.0 11.7 34.3 5.5 1.3 17.7 2.1 4.3 0.0 3.7 13.1 0.1 48.1 22.4 19.8 7.5 0.4 24.2 30.4 15.8 20.2 10.2 0.1 0.0 0.0 41.7 0.0 29.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 6.6 7.2 3.4 5.8 5.6 3.6 5.3 6.7 5.2 5.7 0.0 7.4 0.0 10.9 7.6 0.8 1.6 2.5 0.0 2.3 0.0 0.0 6.3 0.0 8.8 0.5 23.9 0.0 0.0 4.2 23.1 83.0 4.1 0.0 0.0 4.2 14.3 0.0 34.4 0.0 1.9 43.4 2.2 15.1 0.0 1.4 29.2 3.0 0.0 42.1 0.0 1.0 58.2 43.4 0.5 8.3 4.4 10.0 0.0 0.6 1.7 FKBP11 FKBP19 ENSG00000134285 "FK506 binding protein 11" Q9NYL4 12 48921518-48926474 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 175.6;salivary gland: 62.0" "Cell type enhanced" "Detected in all" 7 "Exocrine glandular cells: 145.3;Melanocytes: 258.1;T-cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "MAIT T-cell: 37.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 44.0;Karpas-707: 40.1;OE19: 56.1;RPMI-8226: 40.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 5.6 4.6 1.1 8.2 1.4 3.7 3.7 0.9 2.2 7.5 6.9 0.9 21.6 9.2 4.4 12.9 4.4 4.8 8.1 3.4 1.3 2.4 4.8 38.4 5.8 16.6 1.0 1.3 3.7 175.6 0.2 12.3 3.3 1.6 4.8 6.3 1.9 62.0 20.9 1.4 1.7 7.6 2.9 1.0 18.7 10.0 1.9 0.9 2.2 4.7 4.9 14.5 8.2 4.3 11.1 8.3 1.1 0.3 5.1 37.6 7.3 2.0 2.7 0.5 0.7 12.0 18.2 1.0 15.9 22.8 17.6 20.8 10.2 11.4 30.9 0.5 25.9 0.2 8.5 5.5 7.0 9.1 6.5 1.1 1.1 2.9 0.1 44.0 0.6 0.8 20.3 13.5 13.5 25.1 7.5 9.9 10.5 0.4 40.1 6.4 5.8 4.6 1.1 1.4 56.1 5.1 12.7 0.7 40.1 2.2 0.4 6.5 1.9 5.3 7.9 3.5 0.6 0.4 0.9 7.9 3.4 0.6 0.3 0.3 23.5 19.4 15.7 2.1 0.7 5.6 0.9 0.2 0.6 22.5 0.3 37.6 11.1 15.6 17.7 0.3 4.8 9.4 14.4 1.1 5.1 0.1 8.3 6.4 7.3 1.1 1.4 0.9 2.2 1.3 2.4 1.0 1.3 1.6 0.9 14.9 18.4 30.6 44.0 25.1 4.9 1.7 35.7 28.1 19.4 8.7 37.3 19.0 6.6 17.0 15.1 19.7 11.7 46.7 145.3 59.9 74.1 89.1 12.7 90.3 9.7 1.6 24.1 49.1 14.2 13.2 25.6 9.7 258.1 5.4 84.9 1.5 80.1 7.0 13.1 12.2 15.0 6.5 22.1 8.0 6.8 18.6 35.4 152.0 40.1 37.6 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FK506 binding protein 14" Q9NWM8 7 30010587-30026684 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 8.8 7.4 8.7 9.2 7.3 5.1 8.8 17.6 7.7 14.9 7.8 4.1 6.9 4.2 12.1 14.2 8.0 8.1 8.5 9.8 7.1 5.2 5.4 9.2 7.6 8.1 9.2 5.2 13.0 9.8 8.6 27.8 10.7 7.1 9.8 6.9 8.4 7.6 10.9 3.3 6.4 5.3 18.8 8.1 6.7 7.2 4.2 7.1 2.6 5.6 5.9 7.7 13.4 8.7 1.6 3.3 2.7 1.2 1.0 1.6 0.6 3.4 2.6 7.4 17.2 19.3 24.8 3.4 17.7 16.6 6.2 12.1 2.2 2.2 1.2 8.4 15.5 7.6 7.6 4.1 6.4 12.4 0.6 5.9 2.8 5.0 6.5 9.8 2.0 4.9 15.5 6.7 10.8 12.8 14.6 13.7 1.8 4.5 2.6 11.1 1.4 1.0 2.4 3.9 3.8 4.8 0.0 5.0 4.0 6.1 3.1 1.9 6.5 6.2 14.2 4.3 9.2 3.2 2.6 11.0 6.6 7.7 11.3 7.0 3.9 4.0 2.1 9.4 1.9 20.6 1.9 1.2 1.2 1.3 0.8 1.0 1.1 1.6 1.1 2.2 1.6 1.5 1.3 2.7 1.0 0.5 3.3 1.4 0.6 8.7 7.3 17.6 7.7 7.1 5.2 9.2 5.2 7.1 7.1 17.9 16.5 3.7 19.2 24.4 15.5 13.5 7.6 2.7 10.3 17.4 25.5 9.5 1.7 6.7 0.3 7.4 3.3 0.0 3.2 24.1 26.4 15.0 2.3 6.6 5.3 14.3 1.2 8.6 2.8 0.0 12.0 5.8 10.1 2.8 7.9 31.5 5.3 14.4 19.4 2.9 19.8 6.5 10.5 0.7 3.3 15.9 13.2 4.3 4.8 24.8 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FK506 binding protein 1A" P62942 20 1368978-1393172 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 63.6;granulocytes: 88.4;monocytes: 94.3" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 152.2;TIME: 176.4" "CAB004639, HPA051798" Uncertain NA NA 16000000 "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 106.0 42.4 67.3 55.0 114.8 44.4 63.5 15.8 55.8 33.2 39.7 22.1 33.8 32.7 45.5 45.9 42.7 33.8 32.0 36.4 51.7 30.6 41.9 41.7 59.2 84.1 26.0 36.5 41.7 57.7 20.6 21.7 65.0 22.5 34.4 49.4 21.4 30.8 40.6 38.9 31.5 37.1 56.0 23.3 68.0 33.0 21.1 28.4 47.4 62.2 39.7 48.3 48.1 37.0 13.3 63.6 88.4 94.3 14.5 18.6 84.3 71.4 19.8 15.8 22.8 53.5 67.2 20.8 45.4 30.8 36.4 33.8 19.8 27.8 29.3 14.6 42.3 52.9 32.9 20.4 83.1 47.9 8.4 22.1 30.0 9.3 37.6 32.9 34.8 16.7 39.0 26.5 33.7 34.8 42.5 152.2 33.0 27.4 15.1 42.8 8.9 34.0 48.0 33.9 25.3 38.8 29.2 27.6 35.4 47.0 18.1 26.3 19.9 22.4 45.3 75.2 22.1 17.7 29.7 176.4 135.4 22.7 28.8 33.5 7.5 16.3 30.6 23.3 35.4 29.9 23.9 79.4 88.4 11.5 94.3 10.2 12.8 13.9 13.2 63.6 13.3 14.8 14.2 77.9 14.5 90.3 31.6 18.6 84.3 67.3 114.8 15.8 55.8 51.7 30.6 26.0 36.5 22.5 28.4 80.4 70.6 192.2 178.9 233.8 16.6 52.9 173.3 66.9 58.0 164.0 0.0 249.8 202.2 393.2 31.1 486.6 196.8 23.3 297.3 496.2 197.8 189.6 142.9 99.4 651.5 33.4 317.5 445.0 487.0 41.0 185.2 363.6 229.5 390.5 244.5 40.1 382.3 768.7 153.1 245.7 11.0 135.8 189.1 153.9 133.6 261.7 193.6 124.6 263.1 202.2 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FK506 binding protein 1B" P68106 2 24049701-24063681 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1;intestine: 24.9" "Cell type enhanced" "Detected in many" 4 "Pancreatic endocrine cells: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 5.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 21.9;NTERA-2: 21.3;SH-SY5Y: 15.5;SuSa: 23.9;TIME: 18.6" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 2.9 5.9 25.0 2.8 30.7 1.9 5.9 15.7 23.1 5.1 7.2 1.6 7.4 24.9 3.6 4.2 4.5 4.5 7.1 3.4 31.1 14.0 4.4 4.6 9.0 2.2 13.0 19.7 4.6 4.9 6.4 2.8 5.6 7.9 5.1 4.6 2.4 3.3 9.2 1.1 3.6 6.7 4.0 5.2 1.8 13.3 1.6 4.4 0.6 5.0 1.1 3.2 7.1 3.5 1.5 2.2 4.4 0.8 0.3 5.4 1.1 0.1 0.9 8.5 0.0 5.4 2.1 3.0 2.8 2.9 1.2 1.8 0.5 1.0 0.0 2.1 5.0 7.7 3.3 12.5 9.8 0.8 1.4 8.0 2.9 0.1 21.9 2.0 0.0 7.0 2.0 2.3 2.9 0.6 7.3 7.9 3.3 0.7 0.0 2.8 0.0 0.9 0.0 21.3 0.7 1.5 1.5 0.7 0.0 0.9 0.5 2.1 15.5 0.1 0.0 2.7 23.9 0.5 1.0 18.6 0.0 2.6 0.1 0.6 0.5 0.2 0.0 3.1 0.0 0.6 1.3 0.8 4.4 0.3 0.7 0.0 0.3 0.6 0.5 2.2 1.5 0.0 0.2 0.1 0.3 0.0 0.4 5.4 1.1 25.0 30.7 15.7 23.1 31.1 14.0 13.0 19.7 7.9 4.4 0.0 5.0 0.0 11.5 8.1 1.2 0.4 28.1 1.4 0.0 7.0 0.0 4.5 11.6 24.5 0.4 9.3 9.3 0.0 33.8 22.1 7.8 15.8 1.1 9.8 6.2 1.6 9.1 11.1 3.4 1.8 2.6 9.4 27.0 19.8 7.9 12.1 37.4 28.1 3.9 4.1 2.5 25.8 11.2 1.4 3.0 6.5 4.3 0.0 3.4 14.5 FKBP2 "FKBP-13, PPIase" ENSG00000173486 "FK506 binding protein 2" P26885 11 64241003-64244132 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 119.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" No No 400000 "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 18.2 35.8 28.9 20.2 35.5 12.1 20.2 18.8 27.1 31.3 28.0 20.3 87.8 39.0 24.4 102.7 20.8 25.5 30.3 28.0 29.7 35.7 40.3 89.6 18.8 17.0 39.3 24.8 22.1 107.2 34.0 57.2 59.2 29.0 26.1 21.9 19.4 59.3 116.6 11.8 18.5 30.2 19.7 28.5 20.9 31.1 19.8 20.6 12.4 63.2 18.6 18.8 21.3 23.9 21.3 119.6 29.0 25.4 20.0 30.7 15.5 24.2 32.0 17.3 35.0 37.5 21.4 24.6 29.4 29.9 22.3 20.7 31.5 54.7 18.0 46.9 36.1 30.5 31.8 13.7 24.4 10.6 22.3 11.9 19.9 42.6 32.1 49.3 16.5 28.0 24.9 36.4 29.5 32.6 32.2 17.7 16.3 14.9 53.9 26.4 40.1 18.0 26.1 20.2 41.7 28.9 16.1 17.1 65.5 40.3 24.4 24.2 21.1 20.2 57.2 32.4 12.7 22.0 14.3 16.7 26.8 23.9 42.6 15.7 32.8 10.2 14.6 35.9 17.4 30.3 29.0 24.5 3.4 24.1 25.4 30.7 21.3 19.2 23.3 23.2 20.5 13.0 18.1 9.1 20.0 20.8 119.6 7.1 15.5 28.9 35.5 18.8 27.1 29.7 35.7 39.3 24.8 29.0 20.6 137.0 150.2 102.0 207.7 146.1 76.1 98.2 310.8 108.4 116.0 369.9 21.6 256.2 349.8 239.2 83.7 136.1 585.6 23.3 222.4 308.7 201.1 281.8 142.9 635.0 211.8 30.2 328.9 152.9 95.0 70.2 213.2 169.2 285.1 186.7 264.4 122.7 276.9 273.5 239.7 629.6 65.3 181.1 142.1 273.8 237.0 146.9 518.9 105.4 226.6 265.6 FKBP3 "FKBP-25, PPIase" ENSG00000100442 "FK506 binding protein 3" Q00688 14 45115600-45135319 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 980000 Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 11.7 13.2 28.1 10.2 40.7 9.8 15.5 25.1 32.1 12.0 14.6 11.4 8.3 13.2 9.9 20.4 14.6 8.8 9.1 31.3 26.0 24.4 16.5 20.5 8.0 14.6 23.2 23.8 9.9 10.9 15.0 17.1 14.0 22.9 17.9 15.2 6.6 10.7 12.2 113.3 11.3 13.9 12.8 19.6 9.9 10.6 13.5 22.4 12.7 12.4 24.2 16.5 12.7 9.3 19.5 27.5 13.5 17.4 15.4 19.4 13.0 37.3 41.6 60.6 31.9 27.0 29.4 23.9 23.0 26.4 36.3 40.1 36.3 32.1 19.9 24.3 25.9 20.6 31.1 45.0 29.6 51.9 28.7 26.8 16.4 32.3 46.9 26.6 28.2 17.7 27.7 30.9 21.1 19.7 33.6 47.3 31.7 23.6 15.1 43.1 45.6 45.3 37.9 30.7 41.9 39.5 43.6 44.7 24.2 58.1 43.2 37.0 14.5 36.8 22.9 35.2 47.7 53.6 21.2 30.4 27.8 48.1 14.5 17.6 25.4 45.1 31.0 16.8 19.5 25.9 11.6 14.6 13.5 13.0 17.2 15.7 19.5 17.5 17.6 21.8 13.6 16.8 18.8 2.3 15.4 17.4 27.5 19.4 13.0 28.1 40.7 25.1 32.1 26.0 24.4 23.2 23.8 22.9 22.4 38.7 36.9 49.1 82.5 42.5 68.8 177.9 45.9 77.6 69.4 89.0 9.8 264.9 213.9 116.4 165.9 49.2 61.3 0.0 64.1 95.4 67.9 74.9 51.0 84.7 113.7 38.1 53.9 39.3 36.8 297.6 74.8 68.0 65.8 155.9 63.2 57.4 80.6 52.6 91.9 168.1 44.8 103.5 53.3 145.7 112.4 41.9 138.0 47.9 83.1 70.8 FKBP4 "FKBP52, FKBP59" ENSG00000004478 "FK506 binding protein 4" Q02790 12 2794953-2805423 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "vagina: 209.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006148, CAB017441, HPA062857" Supported Enhanced Nucleoplasm,Cytosol NA NA 110000 Cytosol Nucleoplasm "CAB017441: AB_10618759, HPA006148: AB_1078875, HPA062857: AB_2684883" "unprognostic (1.46e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.12e-5)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-1)" "unprognostic (3.14e-1)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (2.22e-1)" 16.2 21.6 26.0 13.7 30.7 13.3 40.7 50.4 31.9 19.9 22.6 22.8 36.2 13.1 20.1 30.7 34.2 25.7 16.4 20.4 25.0 32.5 31.6 31.3 15.8 11.7 44.7 23.4 23.9 30.3 30.1 19.5 32.0 39.4 30.2 25.3 11.5 30.1 31.6 33.5 25.3 16.1 26.4 25.2 11.5 25.3 36.0 42.1 15.6 47.1 16.5 18.5 17.4 209.6 13.8 6.0 10.9 13.7 8.4 14.0 9.9 15.3 34.2 9.9 16.6 12.3 7.3 47.5 15.1 5.4 25.0 16.9 34.0 18.8 20.5 4.3 9.7 17.4 21.1 61.5 20.5 30.1 37.5 39.4 22.6 25.1 12.0 9.5 17.6 6.2 6.6 18.8 29.5 29.6 14.9 14.5 20.8 20.7 29.3 10.0 44.1 30.9 16.0 84.3 45.3 24.7 18.6 17.4 12.3 21.0 19.6 14.3 20.5 17.5 47.8 7.6 64.7 64.4 12.0 7.7 12.3 38.7 13.8 38.0 7.3 11.2 30.3 10.9 26.4 12.5 10.9 10.8 5.9 12.5 9.8 14.0 13.3 11.1 11.8 6.0 13.8 11.8 13.7 1.5 8.4 13.7 5.3 10.1 9.9 26.0 30.7 50.4 31.9 25.0 32.5 44.7 23.4 39.4 42.1 6.0 8.6 47.9 182.5 127.9 60.2 11.7 40.8 16.0 12.5 50.6 70.7 148.6 131.0 77.3 90.2 33.8 86.8 0.0 22.4 85.7 62.6 189.3 39.1 41.9 54.7 92.2 101.7 12.3 15.0 26.1 32.2 42.7 87.7 52.3 61.6 41.8 62.2 84.2 36.4 112.7 51.3 84.1 88.6 179.1 92.0 116.1 186.7 20.2 77.5 121.3 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FK506 binding protein 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 277.2" "Cell type enhanced" "Detected in many" 7 "Kupffer cells: 325.8;Peritubular cells: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 103.4;ASC TERT1: 64.4;HHSteC: 81.0;HSkMC: 97.8;hTCEpi: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 78.8 20.7 9.5 14.2 15.6 4.9 36.7 2.4 10.9 16.5 29.0 5.1 29.8 2.2 18.6 16.9 29.2 19.4 17.9 26.3 10.6 4.2 44.9 30.7 19.7 55.9 15.7 3.6 27.2 43.7 8.6 33.8 6.0 13.1 18.3 8.2 11.8 30.4 25.1 277.2 20.2 36.7 18.6 18.2 32.3 25.0 14.3 12.4 20.1 24.2 9.8 16.8 22.5 18.4 4.0 30.6 24.9 31.2 11.8 42.3 39.9 5.0 2.2 9.7 14.4 103.4 64.4 0.1 2.7 0.1 1.8 4.1 3.8 0.9 25.0 2.6 0.5 1.5 0.0 5.7 12.1 4.3 9.8 5.5 10.7 1.9 5.3 81.0 6.7 1.1 97.8 49.2 3.1 29.7 1.9 10.5 5.0 11.4 10.2 19.0 3.2 27.9 12.6 2.5 1.1 1.6 12.4 2.5 12.2 8.0 3.0 3.7 2.2 2.2 2.6 0.5 2.2 14.3 7.9 23.2 2.6 2.3 0.3 3.8 4.6 5.3 31.7 0.8 13.2 1.0 13.7 31.2 19.4 20.0 27.0 23.8 3.0 28.2 20.8 30.6 4.0 42.3 30.2 24.9 11.8 12.0 9.2 10.3 39.9 9.5 15.6 2.4 10.9 10.6 4.2 15.7 3.6 13.1 12.4 11.9 9.9 41.7 52.1 15.7 1.7 110.1 79.0 21.4 13.6 5.2 0.0 0.6 19.9 0.5 8.8 66.1 19.7 163.5 6.9 0.9 22.2 38.7 36.0 165.7 28.8 0.0 20.1 130.8 325.8 11.8 149.0 56.5 6.8 91.0 17.5 3.7 3.3 9.3 205.4 16.3 18.2 142.3 28.8 11.6 19.2 18.6 0.3 117.1 19.5 19.5 FKBP7 FKBP23 ENSG00000079150 "FK506 binding protein 7" Q9Y680 2 178463664-178478600 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 116.0;Fibroblasts: 67.2;Leydig cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 52.8;ASC TERT1: 32.8;HSkMC: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.6 4.6 1.5 4.3 4.1 0.7 11.1 3.5 2.3 20.5 6.9 1.0 10.0 1.8 21.4 21.9 8.4 12.4 12.8 12.1 1.5 1.5 5.5 7.4 6.8 5.2 4.0 1.8 34.6 4.3 1.5 11.1 8.2 2.9 19.5 4.2 7.1 4.9 9.7 4.4 4.0 3.9 19.9 3.9 3.0 5.3 8.3 2.2 2.2 8.7 8.0 2.3 15.5 9.9 2.8 5.8 0.2 1.6 1.2 2.8 0.8 0.0 0.6 6.1 9.0 52.8 32.8 0.5 10.9 18.1 2.0 6.4 0.1 0.6 1.7 2.4 19.9 1.8 0.1 2.3 0.9 3.5 1.4 1.3 1.7 2.5 1.7 8.1 1.1 1.3 22.0 0.5 8.0 1.1 14.7 6.5 2.1 0.8 1.1 8.4 0.1 1.9 1.9 1.2 1.1 0.9 2.5 10.7 2.3 2.7 0.2 3.2 10.6 2.3 0.0 1.8 4.5 0.1 2.1 6.0 3.7 2.3 4.3 1.0 2.1 2.2 0.8 6.8 2.7 8.0 0.0 1.1 0.1 2.3 1.6 2.8 2.8 2.0 1.6 5.8 1.7 2.2 2.4 0.2 1.2 0.0 4.5 2.2 0.8 1.5 4.1 3.5 2.3 1.5 1.5 4.0 1.8 2.9 2.2 6.0 2.6 2.2 6.7 6.3 4.6 12.6 2.5 2.7 3.4 7.0 0.0 6.2 1.7 9.1 116.0 18.6 0.1 0.0 7.4 18.5 67.2 3.6 13.9 9.8 5.3 4.8 1.2 13.5 4.3 22.0 59.2 4.8 16.9 1.8 4.8 3.7 4.0 0.0 45.6 3.5 3.3 6.5 39.2 3.7 5.5 5.1 4.2 5.0 2.6 3.4 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FK506 binding protein 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Late spermatids: 972.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 32.5;neutrophil: 31.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 44.3 38.1 75.9 27.5 82.1 82.5 26.5 43.4 113.7 35.2 31.9 41.2 34.6 31.1 31.4 27.2 48.7 39.3 34.5 43.4 69.6 62.1 28.9 42.7 34.3 31.1 55.3 54.3 56.1 60.4 28.8 42.2 36.6 51.2 36.5 12.9 31.9 73.1 46.1 56.7 35.1 31.6 34.6 46.3 36.7 31.9 49.5 26.9 32.1 38.8 24.2 30.7 36.3 45.8 4.3 4.3 32.5 6.9 3.1 6.6 9.1 36.9 26.5 20.8 39.5 21.5 33.8 52.2 29.9 31.9 22.9 31.8 25.1 50.5 21.2 48.7 36.7 15.4 20.1 12.8 41.7 6.5 25.8 60.9 19.8 34.6 30.2 37.0 19.6 43.6 44.1 40.2 20.6 13.1 44.1 23.5 41.3 41.4 50.5 19.9 61.6 35.6 58.7 42.5 33.2 38.5 37.4 17.3 72.4 30.8 24.2 23.1 42.1 21.0 17.3 37.3 16.5 20.4 57.2 27.4 28.7 26.2 55.9 22.7 38.6 22.2 24.6 64.8 31.5 25.4 6.3 5.6 32.5 6.0 5.8 5.5 4.1 6.1 6.6 4.3 4.3 4.7 5.3 31.0 3.1 6.9 4.3 6.0 9.1 75.9 82.1 43.4 113.7 69.6 62.1 55.3 54.3 51.2 26.9 8.9 1.4 107.1 128.1 84.6 57.2 2.0 71.4 2.7 5.7 96.0 13.7 219.4 210.5 151.9 314.6 76.6 289.8 233.6 111.8 173.9 174.8 132.3 54.0 55.9 208.7 93.8 197.7 79.8 159.9 972.7 188.7 127.3 192.3 254.3 108.6 104.6 130.6 224.5 155.6 222.1 41.3 97.0 149.9 203.6 97.7 103.1 261.7 163.0 127.0 126.6 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FK506 binding protein 9" O95302 7 32957404-33006931 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 58.4;fHDF/TERT166: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 35.4 21.1 9.7 12.5 13.6 0.9 43.7 4.5 16.3 33.6 18.3 9.3 16.8 8.8 31.3 30.9 23.7 24.1 28.8 44.4 9.7 11.9 18.2 10.1 30.6 17.5 10.8 9.7 25.9 26.0 12.9 16.0 35.2 13.2 23.7 21.2 30.4 16.0 25.6 17.1 28.0 13.4 37.0 12.8 10.7 17.4 16.3 6.4 2.9 18.9 19.4 11.1 23.7 23.6 0.4 1.4 7.4 4.1 0.3 0.1 0.9 7.1 13.6 5.3 21.9 50.4 58.4 7.1 38.7 40.3 12.8 20.4 5.9 17.0 0.0 15.8 71.8 20.5 14.0 7.8 18.9 14.7 0.0 2.3 1.2 14.6 5.8 21.0 0.0 2.1 37.9 11.5 11.4 11.1 30.5 16.1 0.0 2.7 1.4 26.0 6.9 0.0 3.6 1.1 14.3 7.2 0.0 14.3 0.0 14.3 2.4 5.0 12.1 22.1 11.3 13.7 14.1 7.9 3.5 21.5 21.0 20.2 13.0 8.8 4.6 8.9 0.0 20.5 0.0 41.7 1.5 4.1 0.9 0.1 2.6 0.1 0.4 0.1 0.0 1.4 0.3 0.1 0.1 7.4 0.3 0.7 0.3 0.0 0.9 9.7 13.6 4.5 16.3 9.7 11.9 10.8 9.7 13.2 6.4 11.9 20.0 0.0 12.5 30.5 7.7 38.3 15.3 6.7 7.9 17.4 9.8 17.1 5.0 16.3 0.5 65.3 16.9 0.0 36.7 25.2 46.6 8.5 5.7 10.5 6.7 11.1 11.7 58.9 6.2 0.7 33.9 4.5 57.3 3.6 27.2 34.3 30.2 17.5 51.9 7.4 4.5 45.3 51.9 0.9 0.9 25.0 11.0 1.3 21.4 8.6 FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355154-133358035 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.3" "Cell type enhanced" "Detected in many" 12 "Enterocytes: 183.8;Hepatocytes: 452.0;Hofbauer cells: 152.7;Proximal tubular cells: 264.0" "Cancer enhanced" "Detected in all" "liver cancer: 61.0" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Uncertain NA NA 2500000 "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" 4.9 3.3 1.9 7.1 2.1 2.2 4.5 1.1 2.4 2.2 15.2 2.6 4.9 20.5 2.1 6.3 3.6 2.8 5.8 6.8 1.6 1.3 14.2 68.3 7.5 6.7 2.1 0.9 3.7 6.9 0.8 2.3 2.0 3.0 2.4 2.2 6.7 18.8 3.0 1.9 2.6 28.3 2.4 1.7 9.7 3.0 2.4 1.2 2.8 2.4 3.3 6.1 2.9 2.6 13.0 28.7 2.1 25.6 5.7 6.0 10.1 11.1 3.5 6.9 14.1 2.0 4.9 12.5 8.9 10.4 3.3 4.1 22.4 6.2 0.0 10.4 6.8 0.0 0.6 2.5 3.1 0.3 4.0 2.4 10.9 5.4 24.1 10.3 11.9 7.4 5.0 0.1 1.3 0.7 1.5 4.6 11.3 10.4 14.8 6.9 11.0 1.8 16.0 4.8 6.6 1.6 10.4 0.2 6.4 3.7 0.0 0.7 5.5 3.3 10.2 12.2 3.7 0.1 18.4 9.1 0.0 9.4 0.0 0.0 7.8 1.2 7.7 2.8 4.9 3.4 0.0 25.6 2.1 6.0 25.6 5.6 12.6 5.4 5.0 20.7 13.0 5.8 5.0 1.2 5.7 5.4 28.7 3.5 10.1 1.9 2.1 1.1 2.4 1.6 1.3 2.1 0.9 3.0 1.2 6.0 10.6 30.7 8.0 10.8 0.0 11.4 25.5 2.7 6.8 8.7 0.0 8.9 26.6 11.7 2.9 12.8 183.8 0.0 10.8 7.3 21.6 10.1 26.5 452.0 152.7 0.0 2.9 25.8 94.2 7.2 9.5 67.5 25.3 76.7 19.9 2.3 15.4 112.3 3.5 264.0 1.0 12.9 9.0 10.9 12.1 8.7 5.5 20.8 22.4 7.6 GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase Q14376 1 23795599-23800804 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Mucus-secreting cells: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007340 Approved Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA007340: AB_1078934" "unprognostic (1.65e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (1.41e-2)" "unprognostic (3.03e-3)" "unprognostic (1.17e-2)" "unprognostic (3.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.59e-1)" "unprognostic (2.65e-1)" "unprognostic (1.56e-2)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (7.51e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.68e-4)" "unprognostic (1.41e-2)" 4.4 5.5 4.8 5.6 6.1 1.8 5.0 4.3 8.7 9.1 22.3 3.2 12.4 20.0 3.0 6.0 26.2 6.4 34.7 3.7 4.0 4.1 18.2 26.1 7.7 3.9 3.7 5.2 2.4 15.9 7.7 3.5 29.4 3.5 4.8 23.8 5.5 32.1 6.9 1.7 3.9 30.4 4.1 3.6 8.6 46.7 3.4 2.6 3.7 2.3 9.8 19.6 8.1 8.4 3.1 10.6 2.0 18.6 19.4 5.2 4.7 16.3 19.7 7.9 12.5 2.9 4.2 7.7 11.2 15.2 19.9 14.9 18.0 55.1 3.9 15.8 6.5 26.7 18.2 7.0 28.7 15.1 8.3 4.5 11.0 10.0 19.5 30.1 4.7 3.3 8.9 15.1 18.3 46.0 20.1 17.0 8.5 12.2 1.0 14.1 17.5 7.8 5.1 2.2 23.0 19.2 9.3 7.7 4.9 32.2 11.0 3.1 7.0 20.3 18.4 19.9 9.4 13.5 3.9 9.3 14.5 21.7 14.9 13.7 5.1 12.2 5.1 15.4 20.2 7.8 1.1 7.7 1.7 5.1 15.5 5.2 3.1 3.1 4.1 10.6 1.0 3.6 2.5 2.0 19.4 18.6 3.0 5.1 4.7 4.8 6.1 4.3 8.7 4.0 4.1 3.7 5.2 3.5 2.6 11.9 33.5 8.2 17.9 6.8 14.3 3.1 40.8 12.0 19.4 38.4 15.7 47.8 29.9 42.8 20.5 9.8 92.2 0.0 103.0 85.9 6.3 18.2 10.4 31.8 81.7 7.9 11.6 9.2 3.7 5.1 4.4 12.2 23.6 29.7 119.4 20.6 62.8 84.5 3.2 64.1 13.1 0.0 5.3 14.6 9.7 4.3 80.6 7.5 58.2 38.3 GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38665910-38741237 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.2" "Cell type enhanced" "Detected in many" 8 "Enterocytes: 102.0;Proximal tubular cells: 198.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 29.7" "Group enriched" "Detected in all" 5 "granulocytes: 13.2;T-cells: 29.7" "Cell line enhanced" "Detected in many" "Karpas-707: 27.8;U-266/70: 31.3" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Approved Nucleoplasm NA NA 570000 Nucleoplasm "HPA035472: AB_10669906, HPA035473: AB_2674642, HPA064835: AB_2732723" "unprognostic (5.02e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (9.20e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (6.65e-2)" "unprognostic (6.45e-2)" "prognostic favorable (9.06e-5)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "prognostic favorable (1.32e-4)" 11.2 54.2 3.1 10.4 2.5 0.7 4.6 1.9 2.7 5.9 28.4 2.5 44.3 22.7 6.8 11.8 3.4 11.6 13.3 7.7 2.5 1.8 39.1 28.8 5.8 6.4 2.4 1.9 6.4 7.9 10.4 2.4 3.1 2.9 8.1 10.7 15.3 7.9 29.1 4.6 2.2 39.8 5.4 3.3 4.1 5.0 4.7 2.1 6.4 7.4 3.3 9.3 6.5 5.2 2.8 4.5 13.2 2.1 2.3 29.7 5.3 0.0 10.6 3.3 0.0 11.1 6.5 5.9 1.3 4.0 3.0 4.9 11.9 5.6 4.1 7.9 5.9 6.0 1.7 4.6 0.3 6.0 18.7 7.7 2.2 2.9 23.7 4.0 0.9 0.1 4.5 0.1 6.8 0.0 4.2 3.4 0.0 6.3 27.8 5.5 0.3 9.1 14.8 5.0 22.6 3.5 5.7 0.2 8.0 3.9 18.4 0.6 4.7 0.0 7.6 5.4 4.4 3.6 2.1 1.3 1.0 0.2 7.3 0.4 31.3 21.1 0.1 6.9 2.6 0.1 13.2 2.1 1.8 10.2 1.5 15.0 2.8 16.0 14.8 4.5 2.5 5.8 5.0 5.1 2.3 0.2 0.4 29.7 5.3 3.1 2.5 1.9 2.7 2.5 1.8 2.4 1.9 2.9 2.1 26.8 11.2 12.5 6.5 6.0 2.9 17.3 22.9 24.1 9.1 66.3 0.0 17.0 21.6 9.1 0.8 9.3 102.0 0.0 13.3 25.1 14.3 6.4 6.9 40.4 91.8 3.2 12.7 6.2 12.3 0.5 18.7 36.1 16.9 12.6 36.5 34.6 10.1 63.0 91.9 198.6 7.1 6.5 9.6 1.0 2.1 5.3 5.3 24.5 72.8 4.7 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 58.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 4.0;monocytes: 4.4;T-cells: 4.0" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 78000 Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 8.3 12.2 6.5 4.9 14.2 0.6 8.8 58.4 12.1 8.4 12.1 12.4 7.8 13.5 6.3 6.9 10.2 5.9 7.2 5.5 5.8 8.5 13.3 16.0 8.4 5.3 9.4 8.1 12.9 5.9 9.0 12.0 12.6 14.4 5.7 14.0 10.8 11.7 8.9 4.1 9.8 11.2 6.8 10.2 4.0 8.8 6.1 7.6 5.4 4.1 8.4 5.8 6.3 5.6 0.6 4.0 0.1 4.4 0.5 4.0 1.9 3.9 3.5 2.4 4.2 8.2 7.8 0.8 7.4 9.9 5.8 11.0 2.9 10.0 2.4 3.7 6.0 7.3 6.0 5.2 4.8 11.8 0.9 5.7 4.0 6.7 3.0 7.9 1.7 8.2 5.3 3.3 7.1 8.1 4.2 50.9 1.8 1.6 2.6 10.8 2.4 1.0 3.0 1.2 4.0 2.5 2.4 9.8 3.0 5.3 4.2 7.7 1.6 7.6 4.7 15.7 1.7 3.4 2.4 17.7 5.6 6.9 6.1 6.5 1.1 1.5 0.5 5.6 2.9 8.0 0.0 4.4 0.1 0.7 3.4 1.2 0.6 1.8 0.8 3.6 0.5 1.2 1.5 0.1 0.5 4.4 4.0 4.0 1.9 6.5 14.2 58.4 12.1 5.8 8.5 9.4 8.1 14.4 7.6 0.0 12.5 5.7 9.1 4.2 10.3 6.2 7.6 25.4 5.7 10.4 9.8 20.3 5.0 10.4 3.2 13.9 15.7 0.0 12.1 9.9 5.9 4.9 2.3 24.6 13.5 7.9 19.5 16.5 14.6 3.3 5.8 7.7 8.5 11.8 26.4 12.9 12.9 23.4 16.6 14.0 15.4 12.9 3.9 13.0 13.4 5.6 27.6 4.4 26.5 12.1 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 321.8;Late spermatids: 797.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 140000000 "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 62.1 66.6 43.4 27.6 58.2 83.3 34.8 62.6 88.7 20.6 36.6 20.8 23.7 48.2 21.1 20.6 45.3 24.2 33.5 107.2 42.0 45.6 51.3 77.9 19.6 29.6 39.3 64.3 22.5 21.4 66.9 33.7 20.4 50.2 23.7 37.2 36.2 34.6 33.9 144.7 29.4 44.3 34.2 22.8 23.1 26.7 19.7 19.0 23.8 26.1 68.5 32.6 32.5 25.2 16.2 26.3 74.8 40.9 14.5 27.5 24.6 76.8 108.3 9.5 74.2 31.2 23.2 22.7 29.7 23.5 37.5 45.2 61.0 27.3 50.7 44.1 29.0 25.5 53.6 57.3 64.5 42.6 56.3 23.2 65.0 52.2 64.2 20.2 84.2 42.4 31.8 26.7 44.2 23.0 47.4 35.0 34.4 33.1 40.1 26.3 65.2 36.6 29.5 25.7 69.7 38.4 34.3 25.1 95.7 46.9 51.8 51.9 30.2 59.8 105.5 21.6 17.8 23.9 26.9 30.1 14.2 31.2 40.1 45.7 74.2 42.1 46.0 47.2 64.1 28.6 38.5 22.9 74.8 22.5 35.2 27.5 16.2 20.7 25.5 26.3 13.3 17.5 20.7 1.6 14.5 40.9 8.7 21.6 24.6 43.4 58.2 62.6 88.7 42.0 45.6 39.3 64.3 50.2 19.0 26.8 40.2 23.1 22.0 23.0 92.5 198.3 38.2 21.4 25.0 54.1 70.7 38.6 97.8 77.9 321.8 30.6 90.3 0.0 57.9 60.0 36.8 27.8 22.0 68.1 78.6 224.1 61.2 47.9 41.6 797.8 34.2 41.9 33.7 45.9 67.6 28.6 75.7 25.9 28.7 79.1 62.2 19.4 38.7 6.9 7.6 28.7 32.8 47.1 102.1 32.5 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320884-77331597 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 90.4" "Cell type enhanced" "Detected in many" 9 "Hepatocytes: 348.1;Late spermatids: 326.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 62000 Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favorable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 4.6 12.9 5.6 5.9 6.8 2.8 8.5 2.1 9.0 5.0 8.1 10.8 7.5 8.1 4.1 9.5 9.0 5.5 8.0 5.5 5.4 5.0 8.9 90.4 4.4 10.7 6.9 6.9 2.8 7.1 9.3 5.1 11.0 5.8 8.0 8.0 9.5 22.5 4.7 14.8 7.4 7.2 3.8 7.9 5.0 5.9 18.2 5.2 8.6 8.3 14.3 8.9 4.9 4.5 8.2 15.3 7.2 16.0 3.4 5.6 5.0 6.5 12.5 9.9 7.0 6.3 8.7 16.8 4.1 4.2 7.7 10.9 4.2 16.5 14.6 5.9 4.8 4.8 8.4 6.7 7.9 7.4 7.7 6.7 7.1 4.8 8.9 9.9 2.6 5.9 8.1 8.6 4.4 7.5 4.3 6.6 8.7 5.9 13.5 5.1 60.8 4.0 5.5 2.9 22.6 10.0 7.0 10.4 11.3 11.7 8.0 10.9 9.9 9.1 18.2 12.9 5.8 29.7 3.9 4.5 6.0 20.4 6.8 3.0 10.1 10.8 12.8 15.6 4.0 7.5 6.6 11.1 7.2 1.9 16.0 1.9 6.4 3.4 2.8 15.3 8.2 2.9 2.4 1.1 3.4 13.5 10.4 5.6 5.0 5.6 6.8 2.1 9.0 5.4 5.0 6.9 6.9 5.8 5.2 6.0 8.1 12.7 18.0 11.8 6.8 12.0 50.9 10.7 5.7 8.7 3.9 76.5 39.7 34.9 105.1 8.7 47.2 23.3 59.7 57.9 10.6 19.8 3.5 348.1 39.6 15.9 27.6 9.8 28.3 326.5 10.9 14.4 16.9 35.1 36.9 20.9 39.0 38.6 5.6 58.4 11.2 0.0 10.3 33.5 24.7 12.3 63.7 7.7 45.9 17.7 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 24.8" "Group enriched" "Detected in many" 10 "granulocytes: 1000.1;Hofbauer cells: 476.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 15.8" "Lineage enriched" "Detected in single" 25 "granulocytes: 15.8" "Group enriched" "Detected in some" 8 "HEL: 32.4;HMC-1: 9.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 170000 "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 14.3 2.9 8.0 1.6 12.1 1.6 5.8 2.0 7.7 5.4 6.9 4.4 0.2 7.5 4.7 3.3 4.1 2.5 9.3 3.0 8.4 3.6 2.5 1.3 12.7 0.9 9.6 2.4 1.5 1.8 1.7 1.5 24.8 9.0 6.4 7.5 2.9 3.8 2.2 1.4 5.8 8.6 5.8 14.6 1.4 4.4 1.8 12.1 1.5 1.2 2.8 1.5 4.5 3.5 0.0 0.1 15.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.0 2.5 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 8.0 12.1 2.0 7.7 8.4 3.6 9.6 2.4 9.0 12.1 11.9 75.3 0.0 0.8 3.7 0.0 0.0 0.0 2.7 6.8 0.0 0.0 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 4.1 4.0 1000.1 0.0 476.4 0.0 6.8 0.0 3.9 0.0 0.3 14.5 3.3 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.1 4.6 4.6 0.0 0.0 0.1 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "placenta: 231.4" "Group enriched" "Detected in some" 23 "Extravillous trophoblasts: 115.9;Syncytiotrophoblasts: 419.8" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 36.4;SuSa: 16.3" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" NA NA "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 0.6 0.0 0.0 0.3 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 231.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.5 11.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 36.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 4.0 0.4 0.5 16.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 115.9 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 419.8 0.0 0.0 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "adrenal gland: 223.2" "Cell type enhanced" "Detected in some" 17 "Enterocytes: 1.6;Exocrine glandular cells: 1.1;Peritubular cells: 2.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Region enriched" "Detected in single" 198 "basal ganglia: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.4;SK-MEL-30: 5.1;SuSa: 1.9;TIME: 1.2;WM-115: 3.2" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" NA NA "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.0 223.2 0.0 0.8 19.8 0.0 0.0 0.0 0.0 0.0 0.5 43.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 1.4 0.0 0.0 5.1 1.9 0.0 0.0 1.2 0.2 0.1 0.1 0.7 0.0 0.0 0.0 0.8 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43451003-43453989 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 130.4;seminal vesicle: 80.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 21.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 39.2;WM-115: 33.2" "Low region specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: AB_10795374" "prognostic favorable (9.18e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.68e-2)" "unprognostic (3.86e-1)" "unprognostic (4.40e-2)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (2.75e-5)" "unprognostic (5.10e-2)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "prognostic favorable (2.72e-5)" 16.5 12.5 11.6 12.1 10.1 5.3 12.8 11.3 9.7 14.6 16.5 13.0 130.4 23.4 15.8 14.8 8.4 15.3 16.7 10.9 9.2 10.0 15.9 25.8 17.8 6.7 10.9 9.3 25.1 34.0 13.8 11.2 10.8 9.0 15.6 7.5 15.0 20.8 80.0 8.8 8.4 22.1 13.4 14.3 7.6 14.1 4.5 11.1 4.9 12.8 9.6 6.4 10.7 11.3 3.2 21.6 6.2 1.2 4.8 5.4 3.0 17.4 2.2 0.7 1.2 3.4 6.4 0.0 15.2 13.7 19.2 12.9 8.9 30.5 0.0 1.1 9.8 7.7 3.2 0.0 16.1 7.9 4.3 6.3 2.8 8.0 0.0 22.7 0.0 0.0 3.8 4.6 21.8 0.0 19.4 39.2 0.1 0.2 0.0 12.9 0.3 2.6 2.9 3.2 1.6 4.5 13.5 0.0 0.1 13.3 0.6 8.3 6.1 17.1 9.6 3.8 2.8 2.5 21.9 18.1 1.2 0.0 3.4 29.7 0.0 0.0 0.0 1.0 4.0 33.2 6.2 1.1 2.4 3.3 0.9 4.1 3.2 5.4 2.6 4.1 2.7 5.1 1.5 0.1 4.8 1.2 21.6 0.5 3.0 11.6 10.1 11.3 9.7 9.2 10.0 10.9 9.3 9.0 11.1 17.9 66.3 11.9 39.0 24.8 15.2 0.3 68.8 10.7 20.5 54.1 9.8 14.0 38.1 94.3 0.9 20.2 81.2 23.3 74.3 97.6 32.9 36.0 43.7 49.7 24.9 7.9 66.7 21.5 7.0 3.1 29.4 17.5 38.8 23.4 57.1 28.8 107.8 112.2 28.7 115.0 14.1 25.8 53.4 0.9 2.1 19.3 10.1 10.0 43.0 29.2 IDI1 ENSG00000067064 "Isopentenyl-diphosphate delta isomerase 1" Q13907 10 1039152-1049170 "Enzymes, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039169 Approved NA NA "HPA039169: AB_10674280" "unprognostic (1.61e-2)" "unprognostic (2.59e-2)" "unprognostic (4.58e-2)" "unprognostic (1.97e-1)" "unprognostic (5.72e-3)" "unprognostic (1.27e-1)" "unprognostic (1.76e-2)" "unprognostic (1.97e-1)" "unprognostic (3.72e-2)" "unprognostic (3.88e-2)" "unprognostic (2.59e-1)" "unprognostic (2.26e-1)" "prognostic favorable (1.46e-4)" "unprognostic (9.63e-2)" "unprognostic (2.01e-2)" "unprognostic (2.19e-3)" "unprognostic (2.61e-2)" 13.6 30.4 23.1 15.2 28.3 47.8 68.8 16.4 39.2 8.8 16.1 22.5 8.0 27.9 7.7 12.6 19.2 6.5 9.9 9.7 23.0 29.2 15.3 67.6 15.6 15.5 21.7 25.3 13.4 13.7 12.3 20.6 10.0 55.9 22.3 15.0 16.9 9.9 7.1 35.1 13.7 17.6 8.3 30.6 17.5 12.9 10.2 14.4 8.5 9.8 16.8 16.3 12.5 11.1 16.1 8.9 36.4 19.6 14.5 18.4 14.8 25.5 9.6 51.3 12.5 21.5 46.9 7.5 10.8 12.2 12.5 26.6 25.2 40.3 23.2 7.1 11.7 29.9 22.3 28.4 51.0 11.4 8.0 26.9 22.6 14.5 28.7 25.1 8.7 11.2 29.6 21.5 34.9 4.6 5.3 9.7 21.6 15.4 32.7 21.0 20.0 16.6 14.3 20.7 20.8 5.7 19.4 24.5 25.8 54.3 22.7 8.0 9.6 13.7 28.3 28.3 16.5 29.4 29.3 9.8 6.9 3.9 20.1 7.7 19.0 17.9 43.7 8.6 25.9 6.2 36.4 9.4 21.9 18.2 17.1 18.4 16.1 14.2 15.2 8.6 14.9 10.7 15.8 25.1 14.5 19.6 8.9 14.9 14.8 23.1 28.3 16.4 39.2 23.0 29.2 21.7 25.3 55.9 14.4 68.5 123.1 100.7 66.5 79.6 74.8 59.3 50.9 54.9 45.5 38.4 35.3 59.8 127.6 39.4 221.4 48.6 87.1 0.0 90.3 44.8 52.3 86.3 97.1 52.9 70.4 60.4 101.5 63.8 60.6 68.2 24.5 54.0 126.5 66.7 65.1 108.3 56.5 59.6 28.0 48.2 63.2 25.8 71.4 47.2 43.8 126.5 156.5 103.8 41.3 93.4 IDI2 IPPI2 ENSG00000148377 "Isopentenyl-diphosphate delta isomerase 2" Q9BXS1 10 1018907-1025859 "Enzymes, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 125 "skeletal muscle: 141.6" "Cell type enhanced" "Detected in some" 13 "Club cells: 1.2;Horizontal cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 1.4;NB-4: 2.7;NTERA-2: 1.5;SK-MEL-30: 3.4" HPA041254 Uncertain Vesicles NA NA Vesicles "HPA041254: AB_10794270" "unprognostic (6.69e-3)" "unprognostic (4.05e-2)" "unprognostic (1.64e-1)" 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 141.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.7 0.5 0.1 0.0 0.7 0.0 0.8 0.1 0.0 1.0 0.0 0.0 0.4 0.4 0.8 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.9 1.4 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.2 0.3 2.7 1.5 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 3.4 0.2 1.0 0.1 0.0 0.1 0.1 0.4 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.1 0.0 0.7 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 ISYNA1 "Ino1, INOS, IPS" ENSG00000105655 "Inositol-3-phosphate synthase 1" Q9NPH2 19 18434388-18438301 "Enzymes, Predicted intracellular proteins" "Inositol biosynthesis, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 83.6" "Cell type enhanced" "Detected in many" 14 "Cytotrophoblasts: 829.0;Sertoli cells: 310.4;Syncytiotrophoblasts: 865.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.0;NK-cells: 11.9;T-cells: 8.5" "Cell line enriched" "Detected in many" 4 "BEWO: 103.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007931, HPA008232, CAB020720" Enhanced Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB020720: , HPA007931: AB_2667940, HPA008232: AB_2668018" "unprognostic (1.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.98e-2)" "unprognostic (3.16e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-2)" "unprognostic (2.49e-1)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.28e-2)" "unprognostic (2.73e-2)" "unprognostic (5.08e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (2.23e-2)" "unprognostic (9.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" 7.9 8.4 7.1 3.0 5.7 4.5 7.1 2.7 6.7 9.9 3.5 10.0 44.2 3.4 13.9 12.3 4.5 20.0 6.5 8.0 5.7 7.4 12.7 4.1 4.7 3.8 4.1 4.1 31.6 25.5 7.7 12.6 44.2 16.2 9.5 1.3 19.3 8.8 34.4 8.2 3.4 3.9 3.0 2.3 10.5 3.7 83.6 3.5 3.0 5.6 3.8 3.3 5.9 7.8 4.0 1.9 0.9 0.2 11.9 8.5 4.9 2.8 8.6 20.5 6.1 0.1 0.0 103.8 1.3 0.2 0.1 0.0 4.9 5.2 0.0 7.0 0.6 0.0 7.4 0.6 0.0 0.0 7.7 23.6 10.3 0.5 15.9 2.2 0.1 0.2 1.6 0.1 0.6 0.1 0.0 1.3 0.2 21.1 0.4 0.0 16.6 0.7 0.7 10.7 2.6 6.9 14.2 0.0 4.8 1.7 0.0 6.3 15.8 0.3 1.9 10.5 4.4 14.0 1.1 3.9 0.1 0.2 0.1 0.3 3.3 1.4 0.6 0.6 0.4 3.6 0.9 0.1 0.0 7.6 0.2 5.9 4.0 7.4 6.7 0.7 2.3 6.1 8.5 0.8 11.9 0.1 1.9 5.2 4.9 7.1 5.7 2.7 6.7 5.7 7.4 4.1 4.1 16.2 3.5 3.0 0.6 2.2 67.1 10.6 0.0 4.2 7.6 4.0 4.5 45.4 2.0 829.0 44.7 34.8 81.2 19.7 1.3 0.0 7.5 57.3 25.4 8.5 13.9 0.9 73.6 0.0 62.2 19.0 5.3 178.1 34.5 3.7 21.9 7.2 2.6 7.2 4.6 0.0 47.4 4.7 0.5 310.4 167.1 59.2 21.8 5.0 865.2 9.6 4.6 31.8 LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease mutation, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported Approved Cytosol NA NA Cytosol "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: AB_2674134" "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.07e-4)" 21.1 22.9 17.9 9.9 38.8 5.0 14.7 22.5 33.9 11.2 16.9 37.7 5.8 26.4 16.6 12.5 23.4 11.0 12.1 17.8 19.0 17.3 8.4 33.8 19.7 8.3 49.5 14.9 25.7 15.8 10.4 22.7 10.3 42.7 24.0 10.7 13.2 11.0 13.2 24.5 26.2 10.3 12.2 33.3 7.1 14.1 13.8 46.9 6.0 7.5 9.8 8.3 12.3 11.8 4.8 8.0 5.2 3.3 2.7 8.3 5.0 18.1 5.9 19.2 8.2 26.1 25.1 5.4 7.0 49.9 8.7 17.1 19.4 14.5 3.9 6.0 13.6 63.9 8.6 16.9 29.4 3.5 3.8 9.1 9.7 9.7 12.5 23.8 3.5 6.8 24.7 11.2 16.2 7.0 6.0 7.2 19.3 9.4 23.5 7.4 6.1 7.6 5.0 31.2 2.9 5.3 9.0 5.9 23.7 22.6 10.0 11.2 9.9 8.3 6.4 7.2 8.6 10.2 8.8 10.7 10.3 8.4 9.1 5.4 8.6 7.3 7.9 10.8 15.6 4.4 5.2 3.3 3.5 6.9 3.0 4.7 4.8 5.0 8.3 3.8 3.0 4.2 6.2 0.0 2.7 2.5 8.0 2.3 5.0 17.9 38.8 22.5 33.9 19.0 17.3 49.5 14.9 42.7 46.9 11.9 33.7 11.5 3.8 32.7 12.9 13.4 12.7 8.1 7.9 10.4 3.9 3.4 0.0 9.7 4.2 9.8 5.3 23.3 15.0 5.1 25.7 14.9 3.5 23.8 8.1 22.3 18.9 9.8 7.8 5.3 19.5 5.0 20.3 19.0 10.0 8.7 10.9 0.0 12.7 3.8 15.2 0.0 10.0 13.6 9.4 47.2 5.3 5.0 10.0 4.1 MCEE GLOD2 ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 76.7;Distal tubular cells: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" No No 16000 Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favorable (4.76e-4)" "prognostic favorable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" 10.5 20.4 8.5 10.1 9.2 4.3 18.9 10.5 9.8 14.1 13.8 9.4 24.6 11.1 8.8 19.7 16.9 8.6 12.6 19.8 6.6 6.2 18.8 39.7 9.1 9.5 13.1 6.6 12.4 29.0 9.8 24.5 9.9 9.1 13.7 13.5 11.1 28.9 20.5 18.2 15.2 14.9 10.9 11.5 10.1 13.1 5.7 11.4 9.3 11.0 18.7 10.9 13.0 13.3 15.9 17.6 20.0 18.4 11.2 24.9 11.1 6.4 3.1 5.7 4.1 19.4 26.4 16.5 9.9 12.6 5.0 7.6 7.7 8.0 9.9 3.0 9.7 3.8 6.7 6.9 5.1 5.3 9.2 6.0 6.8 8.7 22.1 10.9 7.6 5.6 17.5 7.5 3.4 6.7 11.2 5.7 7.9 8.9 17.4 4.8 8.2 5.6 8.9 5.2 17.7 7.7 6.7 6.5 18.4 7.7 5.2 6.5 4.7 3.7 21.9 9.7 6.9 17.3 7.3 7.4 5.9 4.6 6.0 3.9 16.7 6.8 10.5 9.6 12.4 5.3 13.0 18.3 20.0 12.8 18.4 17.3 15.9 15.7 12.3 14.9 13.2 14.6 12.3 4.5 11.2 17.6 17.6 24.9 11.1 8.5 9.2 10.5 9.8 6.6 6.2 13.1 6.6 9.1 11.4 23.8 8.3 13.7 11.3 7.6 2.6 76.7 22.9 17.4 9.1 5.2 2.0 30.6 77.9 10.4 0.8 9.0 14.7 0.0 16.1 27.7 21.1 8.8 0.0 60.2 13.5 4.8 8.6 9.8 11.6 0.9 27.0 11.2 13.5 3.6 28.7 6.7 10.6 10.5 16.6 64.3 8.7 25.8 10.8 2.4 4.1 18.2 9.5 12.9 25.1 9.2 MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894004-23895227 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Distal tubular cells: 1397.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 129.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Supported Nucleoplasm,Cytosol "Secreted to blood" No No 13800000 14000000 Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" 30.6 49.8 43.9 42.0 39.9 46.0 71.6 19.0 66.1 23.0 42.7 10.4 55.6 39.9 22.5 113.3 51.9 23.3 42.5 60.7 42.8 40.3 71.8 58.8 46.2 113.9 33.5 43.7 24.5 80.2 16.2 41.1 30.5 45.2 54.8 11.6 15.0 57.3 101.2 36.0 63.3 50.6 26.7 78.3 42.5 56.2 24.9 19.2 19.0 28.9 43.7 16.7 21.4 44.6 56.8 42.5 17.6 23.8 38.3 52.7 66.0 49.8 11.0 2.4 11.2 0.9 2.3 18.7 18.8 3.1 6.1 7.8 8.3 8.2 23.7 14.9 1.3 2.8 22.2 2.6 11.4 0.7 19.9 129.4 8.9 10.1 17.2 4.9 34.6 21.1 4.7 6.8 3.6 1.7 4.5 4.8 17.8 13.8 12.1 2.0 25.1 23.5 64.2 14.3 9.8 60.3 30.2 4.1 66.5 4.7 3.4 32.5 37.8 12.0 12.7 31.0 0.6 16.4 10.4 13.7 5.3 35.6 3.2 0.4 52.3 18.4 24.4 21.5 12.9 10.8 16.3 23.8 17.6 37.4 22.3 52.7 56.8 51.8 40.4 31.6 49.1 46.1 38.0 7.1 38.3 14.6 42.5 48.3 66.0 43.9 39.9 19.0 66.1 42.8 40.3 33.5 43.7 45.2 19.2 145.9 147.8 297.7 257.6 597.1 25.5 0.3 433.1 384.1 354.8 657.8 2.0 427.6 1397.6 643.7 166.1 220.2 275.4 0.0 324.9 742.0 370.2 224.8 172.4 900.8 252.9 20.6 335.5 293.4 221.5 97.3 311.3 223.0 733.9 288.6 378.1 30.6 687.0 340.1 284.6 1307.4 25.0 135.8 432.6 7.9 117.5 663.2 573.7 251.6 418.6 198.5 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 170000 Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 13.6 33.3 24.2 11.2 26.2 7.4 14.7 19.2 33.7 16.7 22.6 26.1 15.3 32.6 15.7 26.8 17.1 20.7 13.4 28.8 22.7 22.2 22.5 30.2 10.6 16.2 28.1 28.3 23.2 34.2 24.7 15.0 11.4 37.4 20.6 23.1 18.3 18.6 17.9 33.3 11.7 27.4 16.4 21.7 14.7 14.3 23.5 17.7 16.4 17.1 15.0 16.6 15.6 11.7 12.8 10.2 2.4 7.4 17.7 27.1 12.9 10.6 14.7 12.2 13.8 28.0 13.6 10.7 9.2 15.0 15.8 22.1 14.5 14.1 15.1 20.0 13.4 12.6 26.6 24.2 26.7 15.0 11.5 30.3 27.1 14.0 15.6 19.9 12.5 8.0 18.1 6.9 14.8 26.7 24.0 21.4 18.2 9.0 12.4 20.3 9.1 13.3 5.5 6.7 16.1 12.6 13.7 11.5 37.0 18.5 12.1 22.9 10.0 10.7 19.4 11.5 18.7 26.5 8.6 9.6 9.5 8.1 7.0 8.9 30.8 18.2 9.9 19.8 18.1 6.9 0.7 7.2 2.4 13.5 7.4 17.5 12.8 18.3 15.4 10.2 12.5 27.1 19.7 1.1 17.7 6.3 8.5 22.7 12.9 24.2 26.2 19.2 33.7 22.7 22.2 28.1 28.3 37.4 17.7 6.0 15.9 13.7 6.7 1.6 21.7 47.5 10.2 5.3 7.9 14.0 3.9 26.1 13.3 15.5 13.7 8.7 34.2 0.0 7.5 9.1 12.2 5.4 15.0 15.8 20.6 33.4 10.4 6.2 5.3 24.3 10.3 5.6 3.3 11.8 18.1 18.3 14.3 17.3 8.1 25.8 16.8 6.5 6.6 23.8 10.1 2.4 13.6 6.9 11.8 4.7 MRI1 "MGC3207, MRDI, mtnA, Ypr118w" ENSG00000037757 "Methylthioribose-1-phosphate isomerase 1" Q9BV20 19 13764532-13774282 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042744, CAB045988" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 2600000 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "CAB045988: AB_2145566, HPA042744: AB_2678141" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-3)" "unprognostic (1.61e-1)" "unprognostic (8.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.75e-2)" "unprognostic (1.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.28e-1)" 14.5 18.5 12.5 21.8 18.3 16.6 16.8 24.5 21.8 21.5 17.2 23.6 23.5 19.0 24.2 21.3 20.7 19.9 17.6 13.5 14.6 12.1 24.4 20.1 15.4 19.5 16.5 14.3 24.0 20.5 21.3 17.3 24.2 17.2 17.8 13.4 18.5 23.4 21.6 13.0 28.6 18.5 13.3 16.6 22.0 19.8 5.0 16.7 20.0 21.8 10.5 18.2 18.1 20.6 5.7 8.9 6.9 5.8 5.0 6.6 3.6 10.7 8.0 4.0 9.6 4.4 8.2 9.8 12.8 7.4 11.6 10.6 8.4 8.6 5.8 5.1 4.7 5.5 18.1 18.6 13.2 7.1 10.1 32.2 4.6 12.7 9.0 3.9 13.9 10.8 8.2 7.3 5.9 4.7 10.5 10.7 5.7 8.8 0.3 5.0 15.8 15.4 8.9 6.6 3.9 22.9 14.5 5.4 13.1 5.9 8.4 8.0 7.2 4.6 10.5 10.0 5.6 8.2 5.1 6.5 6.0 5.5 21.2 6.2 7.9 8.3 1.7 5.1 16.1 7.1 6.9 5.5 1.9 6.2 5.8 6.0 5.0 5.3 6.6 4.7 5.7 4.3 3.3 4.1 5.0 3.2 8.9 4.8 3.6 12.5 18.3 24.5 21.8 14.6 12.1 16.5 14.3 17.2 16.7 8.9 16.6 10.8 9.0 9.8 3.1 0.8 5.1 20.1 14.8 15.7 7.9 10.1 5.0 8.2 0.6 6.0 9.1 0.0 11.0 7.7 8.5 6.0 12.7 9.0 6.3 1.6 8.7 12.3 8.9 1.4 16.1 8.5 1.7 6.4 9.4 3.3 5.8 11.0 14.2 8.1 6.3 25.8 5.5 0.4 3.9 9.9 4.5 14.4 9.1 8.0 MUT ENSG00000146085 "Methylmalonyl-CoA mutase" P22033 6 49430360-49463191 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Isomerase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.5" "Cell type enhanced" "Detected in many" 6 "Hepatocytes: 117.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035971, HPA035972" Enhanced Approved Mitochondria,Cytosol NA NA 110000 Cytosol Mitochondria "HPA035971: AB_10696648, HPA035972: AB_2674895" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.72e-2)" "unprognostic (3.18e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (1.89e-2)" "unprognostic (6.57e-2)" "unprognostic (9.89e-2)" "prognostic favorable (8.71e-13)" "unprognostic (5.38e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-3)" "unprognostic (1.91e-1)" 10.7 14.3 10.9 5.7 13.4 4.1 9.7 10.0 12.1 8.9 12.7 8.6 9.0 13.6 8.7 8.6 13.2 8.4 7.5 16.6 10.1 10.0 25.5 96.5 7.8 5.7 11.8 9.5 13.1 15.7 15.8 13.5 7.5 12.0 11.2 11.2 8.0 9.3 9.2 13.7 9.0 14.7 11.8 9.7 6.4 10.9 9.1 9.9 8.2 11.2 9.1 5.8 12.8 8.1 9.4 8.9 14.0 15.2 14.2 12.0 6.7 13.4 4.8 14.5 16.9 28.9 27.5 8.0 12.1 16.0 12.8 19.0 5.5 7.0 12.5 9.7 12.9 19.4 7.7 16.1 8.6 18.1 10.6 11.7 6.6 11.0 14.4 21.1 8.5 6.4 16.6 12.8 13.0 15.2 11.5 12.3 13.6 12.0 15.0 15.0 8.4 9.9 8.4 6.2 14.2 3.5 8.9 18.2 17.2 14.8 12.9 13.5 9.4 13.3 9.6 20.0 15.9 8.3 13.6 8.8 11.9 8.8 16.1 16.3 5.9 6.7 10.7 16.8 10.0 10.4 14.0 7.5 12.5 7.9 9.9 9.9 9.4 9.5 9.9 8.9 8.3 12.0 9.0 4.3 14.2 15.2 6.3 11.9 6.7 10.9 13.4 10.0 12.1 10.1 10.0 11.8 9.5 12.0 9.9 17.9 17.4 10.4 16.2 17.7 16.5 60.2 22.9 18.7 21.6 31.4 2.0 21.2 24.9 14.4 5.7 10.0 27.4 0.0 12.8 11.2 13.8 13.3 10.4 117.7 10.8 19.1 50.0 14.1 10.0 2.1 22.2 9.4 8.5 2.8 23.1 28.2 10.5 23.0 26.2 34.2 15.2 32.3 12.2 18.6 14.3 17.6 27.9 7.9 21.2 11.5 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591762-156594299 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cytotrophoblasts: 120.4;Distal tubular cells: 170.8;Proximal tubular cells: 189.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 19.1 29.9 31.6 14.4 28.5 12.1 22.6 17.6 42.5 23.0 30.0 31.0 17.4 28.4 28.5 57.9 23.4 29.4 25.8 46.3 28.5 25.0 41.6 41.0 17.2 16.9 33.2 29.3 29.3 37.3 36.3 29.0 21.8 28.8 27.9 26.6 23.0 29.5 36.3 30.9 20.2 25.9 25.0 29.1 17.4 25.0 29.5 22.2 17.7 32.4 19.5 20.4 20.8 18.3 52.4 53.8 12.4 26.5 31.6 32.5 40.6 31.6 42.0 13.4 24.0 17.9 12.3 16.0 10.9 16.7 18.7 19.8 34.9 21.3 21.5 33.2 13.9 16.2 30.9 13.4 26.1 13.3 22.7 29.3 17.8 24.0 23.1 20.5 22.3 18.3 12.3 33.8 23.8 22.2 15.0 25.4 29.0 18.1 19.6 19.1 56.3 24.5 27.2 16.6 43.8 32.8 24.7 12.6 56.8 25.3 26.3 32.5 31.0 26.2 50.1 38.5 19.8 48.6 32.9 14.8 13.5 21.1 19.1 23.8 50.8 30.7 20.5 18.6 13.3 20.8 4.9 24.1 12.4 31.6 26.5 31.3 52.4 29.2 32.2 21.7 41.7 32.5 30.9 2.9 31.6 20.6 53.8 25.5 40.6 31.6 28.5 17.6 42.5 28.5 25.0 33.2 29.3 28.8 22.2 38.7 23.3 0.0 0.0 0.0 0.0 0.0 0.0 21.4 43.3 64.6 0.0 120.4 170.8 89.3 0.0 0.0 0.0 0.0 87.1 28.1 0.0 0.0 4.7 0.0 80.7 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 71.3 0.0 0.0 83.0 0.0 0.0 189.4 0.0 0.0 0.0 0.0 0.0 0.0 68.0 0.0 0.0 0.0 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600614-42648741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: AB_2681540" "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favorable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.01e-4)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.05e-5)" 12.9 14.4 9.8 18.8 22.2 16.3 15.9 42.0 12.3 18.8 10.4 18.5 15.4 11.8 27.2 17.4 11.0 12.0 13.1 11.2 10.9 10.5 9.5 9.7 14.6 15.5 14.5 11.3 22.7 18.4 19.2 26.9 11.1 14.1 12.9 11.1 20.4 13.2 19.5 12.0 20.0 13.3 19.4 15.0 18.5 10.1 17.8 13.8 20.6 14.9 10.9 19.4 12.9 13.9 9.3 8.5 11.7 10.0 11.1 10.2 3.6 8.9 5.2 17.2 7.0 10.3 12.6 9.7 14.6 3.7 6.1 8.3 9.0 7.2 14.2 7.0 4.4 6.0 7.9 10.1 3.7 12.5 7.1 8.5 18.2 16.3 14.6 4.4 14.0 12.0 5.1 7.2 12.0 4.6 11.1 10.7 3.4 18.3 11.0 11.5 3.7 9.5 13.7 14.8 4.8 7.6 10.1 7.7 5.8 8.5 6.9 6.1 3.6 15.7 6.5 2.4 8.0 9.6 10.2 17.1 10.9 8.0 11.9 14.0 9.5 13.3 9.9 5.8 17.2 6.7 9.2 6.2 11.7 10.2 7.7 9.4 8.9 9.8 8.5 4.7 9.3 10.0 8.7 9.1 11.1 10.0 8.5 8.3 3.6 9.8 22.2 42.0 12.3 10.9 10.5 14.5 11.3 14.1 13.8 101.3 122.0 67.1 53.1 52.4 190.3 63.1 50.9 45.5 75.1 83.7 231.7 56.8 14.9 39.7 13.6 120.9 75.7 23.3 34.0 42.2 62.5 58.7 92.6 44.7 39.4 125.5 69.0 103.2 49.9 13.7 155.3 72.2 49.0 62.3 51.5 160.2 38.7 44.6 126.2 9.7 283.7 90.5 58.5 210.1 183.7 50.1 26.2 126.8 54.0 42.1 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860694 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 383.4;pancreas: 677.5" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 1160.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" No No 140000000 "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 18.0 34.7 6.3 15.4 8.4 35.0 16.1 6.1 6.5 22.1 40.5 9.0 45.0 42.6 14.7 29.1 40.3 12.8 42.3 20.7 6.3 5.9 27.2 383.4 20.9 29.1 7.9 4.5 14.3 677.5 6.4 23.4 58.5 7.2 22.5 8.5 12.3 251.9 42.5 31.0 24.3 112.8 11.0 5.2 36.7 31.6 9.1 7.2 10.5 29.7 50.7 46.4 16.5 20.5 21.6 71.3 45.8 60.8 38.8 55.9 70.8 58.4 50.9 18.9 60.8 51.0 60.1 44.7 114.3 73.7 49.8 67.5 37.4 51.3 23.6 50.3 73.4 30.1 41.5 20.7 44.7 28.9 15.2 35.1 35.3 53.6 152.0 67.1 111.5 58.5 45.3 30.4 39.9 42.3 64.5 82.1 16.9 25.0 102.0 35.5 53.4 31.9 88.6 14.8 62.0 46.4 26.1 33.8 46.8 38.7 70.7 22.7 25.1 57.0 164.5 59.3 32.6 74.4 131.4 63.7 93.6 46.9 53.1 55.7 73.4 53.1 22.3 123.0 43.0 71.3 45.8 60.8 38.3 53.5 38.7 55.9 21.6 36.4 42.8 43.4 18.7 21.2 31.5 20.0 38.8 27.6 71.3 25.7 70.8 6.3 8.4 6.1 6.5 6.3 5.9 7.9 4.5 7.2 7.2 95.3 135.6 82.0 139.4 106.7 53.8 19.6 234.4 58.9 83.0 106.4 31.4 682.3 34.9 562.2 31.8 104.1 635.2 0.0 930.3 1160.9 218.5 265.2 99.1 768.8 403.4 58.8 191.7 211.1 166.1 51.9 130.9 120.0 129.9 349.9 361.7 113.5 636.3 443.3 105.4 92.7 40.7 155.2 103.8 85.8 107.3 126.5 837.3 139.5 385.8 170.2 PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283152-287215 "Enzymes, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "pancreas: 286.5" "Cell type enriched" "Detected in some" 6 "Exocrine glandular cells: 253.2" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Region enhanced" "Detected in many" "cerebellum: 15.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.2;HEK 293: 11.6;Hep G2: 8.6;Karpas-707: 4.0;MCF7: 6.1;SH-SY5Y: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" NA NA "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" 0.3 0.3 2.1 0.2 1.5 0.3 0.2 15.3 3.0 0.2 0.7 4.3 0.2 2.9 0.2 0.3 0.2 0.2 0.8 0.4 2.8 3.0 0.2 0.2 0.2 0.2 4.0 0.5 0.4 286.5 0.2 0.2 0.5 2.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 1.0 0.2 5.4 0.2 10.2 0.3 2.8 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.1 0.1 0.1 5.2 0.2 0.7 0.1 11.6 0.0 0.3 8.6 1.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.2 0.0 0.4 4.0 0.2 6.1 0.2 0.6 0.4 2.1 0.0 0.1 0.0 1.1 0.0 0.0 2.2 5.0 0.0 0.1 0.0 0.7 1.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.5 15.3 3.0 2.8 3.0 4.0 0.5 2.2 2.8 0.0 0.3 0.0 0.0 0.5 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 253.2 0.6 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.0 0.2 39.2 0.3 0.4 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.9 0.0 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746392-43773279 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Syncytiotrophoblasts: 877.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 390000000 "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 16.9 21.2 10.0 20.5 13.5 20.8 31.1 12.7 9.2 24.7 19.4 12.3 33.9 22.2 19.7 42.4 21.7 18.4 25.1 20.6 10.2 12.7 27.3 112.5 20.0 34.6 12.4 10.3 22.4 46.8 21.1 21.7 44.0 13.3 24.6 21.2 13.7 43.4 36.9 8.7 17.9 28.8 15.8 11.4 25.2 20.5 17.1 14.3 15.6 74.0 16.4 19.8 14.7 28.3 7.7 18.3 13.5 10.8 11.7 14.1 14.5 12.3 4.6 9.8 21.9 19.9 21.4 30.1 24.7 24.5 18.4 22.9 12.9 12.7 14.1 16.1 28.2 12.3 19.7 12.4 24.0 16.1 10.2 18.4 19.1 7.4 11.9 32.8 10.7 13.9 13.7 19.9 13.9 23.5 21.7 32.0 4.5 11.0 6.9 17.9 4.2 3.6 12.2 9.9 19.0 18.7 7.1 15.4 10.6 15.7 10.1 9.9 11.0 20.6 19.8 7.8 10.4 13.8 11.0 21.6 15.3 8.1 12.3 12.0 3.2 3.6 14.8 19.6 17.0 11.5 10.0 10.3 13.5 13.4 10.5 14.1 6.5 8.5 10.8 9.6 7.7 7.2 8.4 2.9 11.7 10.8 18.3 6.7 14.5 10.0 13.5 12.7 9.2 10.2 12.7 12.4 10.3 13.3 14.3 178.6 134.5 154.1 249.6 170.7 50.3 49.5 142.7 231.6 287.8 158.7 39.3 559.5 59.7 337.0 18.9 151.7 227.1 23.3 345.2 636.6 296.9 292.3 254.2 280.2 396.2 66.7 178.5 269.5 152.1 20.5 234.7 267.6 231.2 285.9 259.4 139.7 260.6 167.0 260.3 106.7 46.2 122.9 160.2 185.1 135.1 129.7 877.1 174.3 233.4 256.5 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028641 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 164.3" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 542.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 12000000 "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavorable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 17.6 13.0 7.7 25.6 11.9 7.4 27.4 5.1 7.9 25.5 20.9 12.1 28.8 18.2 19.4 46.3 15.2 20.8 28.1 16.9 7.3 8.0 27.7 164.3 19.1 29.1 11.6 6.2 19.4 76.3 7.0 19.1 24.7 12.0 18.0 21.9 7.8 36.4 26.5 5.8 10.1 21.3 17.8 13.9 27.9 23.7 11.5 11.3 19.2 89.8 11.9 24.3 17.4 22.6 26.6 63.3 16.2 21.2 21.5 35.9 34.5 32.4 30.9 33.6 93.9 30.7 21.9 48.7 45.7 30.6 26.2 42.8 25.6 87.8 23.4 102.6 37.5 72.2 21.3 22.6 43.3 23.1 16.6 13.3 11.2 8.9 56.1 41.2 25.5 31.7 21.5 19.4 28.7 23.1 34.2 53.2 12.0 18.3 63.8 23.0 35.5 24.3 29.1 50.1 66.4 18.0 16.0 26.1 56.6 30.6 25.5 10.7 28.2 41.5 29.9 15.9 41.9 17.0 19.7 29.0 20.7 11.7 50.1 32.1 48.6 21.8 16.4 48.3 30.2 70.3 16.2 20.1 12.1 34.3 21.2 35.9 26.6 22.6 26.7 19.4 15.1 21.5 22.7 2.7 21.5 21.0 63.3 16.6 34.5 7.7 11.9 5.1 7.9 7.3 8.0 11.6 6.2 12.0 11.3 26.8 33.4 29.0 71.4 30.8 3.3 20.4 96.8 65.6 44.3 40.1 3.9 152.3 13.3 102.2 2.7 35.1 89.5 46.7 79.9 277.0 90.5 103.6 57.6 542.5 131.4 0.0 59.1 95.8 80.7 3.2 54.7 53.4 82.7 48.7 104.5 19.3 96.2 87.1 40.3 54.4 6.1 32.3 34.2 53.4 71.9 25.0 192.7 54.6 97.0 59.2 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067062-123225227 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.0" "Cell type enhanced" "Detected in many" 8 "Extravillous trophoblasts: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 2900000 "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 11.6 17.1 2.6 11.2 3.1 6.3 9.3 1.0 4.0 10.0 11.0 2.4 10.9 5.6 12.2 17.1 6.7 9.1 22.2 7.2 2.5 1.2 11.0 66.0 14.4 7.1 2.2 1.8 11.4 18.3 5.2 12.1 29.1 1.9 14.3 10.8 12.7 10.8 7.6 8.1 6.1 8.2 9.5 2.3 8.6 17.6 18.0 2.5 3.2 18.2 5.5 7.9 7.8 6.9 3.2 12.8 0.3 9.0 0.5 2.4 2.3 8.2 5.1 6.4 7.7 29.4 26.7 34.1 15.8 26.5 8.8 24.4 16.3 7.6 0.0 20.6 24.4 5.7 4.4 2.8 9.6 9.4 0.2 3.1 3.6 1.5 19.4 12.2 9.1 0.6 22.8 14.5 6.0 12.6 9.5 29.8 3.5 4.6 21.6 6.0 10.1 2.4 10.6 4.7 18.9 5.3 2.3 4.6 22.8 7.4 4.8 6.9 4.2 7.7 8.6 13.5 10.9 7.5 11.1 16.6 2.3 7.3 10.6 4.2 6.4 1.7 3.7 7.3 7.2 7.7 0.0 9.0 0.3 1.4 2.2 2.4 3.2 1.0 0.9 5.4 0.8 0.6 0.6 0.2 0.5 0.4 12.8 0.0 2.3 2.6 3.1 1.0 4.0 2.5 1.2 2.2 1.8 1.9 2.5 17.9 27.8 1.5 3.6 4.4 9.3 2.0 25.5 8.1 13.6 5.2 37.3 39.8 0.0 28.0 1.1 21.8 3.3 0.0 25.3 119.9 23.6 13.9 3.5 42.3 10.8 0.0 8.1 37.4 8.4 1.5 22.5 4.5 8.5 1.8 26.1 2.0 13.8 3.5 20.8 4.9 29.6 12.9 7.3 1.2 1.5 3.6 42.0 2.2 16.3 4.3 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Extravillous trophoblasts: 955.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 53000000 "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 26.9 32.7 16.7 25.0 29.9 19.9 28.7 11.3 16.8 33.4 26.1 13.9 53.7 20.4 30.4 76.1 27.1 25.5 22.4 32.7 14.2 13.9 42.1 118.4 30.4 36.3 17.8 12.7 26.5 141.6 24.9 23.3 39.5 19.0 22.6 30.1 14.6 53.4 45.0 15.7 16.1 28.4 26.5 14.3 35.1 30.9 12.4 19.5 18.1 97.9 20.1 29.7 21.9 30.6 45.2 61.0 52.0 46.2 51.5 52.2 59.7 33.2 36.1 51.7 81.1 66.6 57.6 92.0 80.9 75.1 42.5 57.3 51.2 65.7 54.0 57.0 79.1 82.6 27.3 38.8 67.7 45.7 42.3 30.6 43.8 28.3 83.1 72.1 44.8 32.9 41.5 52.1 41.1 74.2 78.8 95.7 20.5 37.6 116.5 41.9 39.4 17.2 46.5 43.2 108.3 28.6 41.4 52.7 97.8 60.5 40.2 33.2 66.5 31.9 46.8 45.4 70.0 16.5 76.1 47.0 39.9 51.0 35.9 46.7 110.0 67.8 35.0 53.9 56.4 55.8 52.0 44.4 20.5 47.5 46.2 52.2 45.2 37.7 44.7 48.6 33.1 18.4 31.0 8.1 51.5 33.9 61.0 37.7 59.7 16.7 29.9 11.3 16.8 14.2 13.9 17.8 12.7 19.0 19.5 53.6 94.6 111.7 205.7 91.5 66.3 27.4 152.8 108.4 161.5 186.7 27.5 420.2 36.5 263.9 6.1 114.4 100.2 23.3 210.7 955.4 173.7 256.1 129.2 285.4 369.6 39.7 151.3 244.9 137.9 12.1 112.2 137.1 189.0 126.2 149.4 95.2 191.3 100.8 126.9 98.3 45.7 84.1 115.4 95.8 139.7 89.6 463.4 112.4 196.3 240.5 PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426160-97433441 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Extravillous trophoblasts: 698.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Approved Supported Nucleoplasm NA NA 200000000 Nucleoplasm "HPA042528: AB_2678039, HPA060483: AB_2684292" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.64e-1)" "unprognostic (5.64e-2)" "unprognostic (1.16e-1)" "unprognostic (9.47e-3)" "unprognostic (7.60e-3)" "unprognostic (1.74e-3)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "unprognostic (2.48e-2)" "unprognostic (1.48e-1)" "unprognostic (5.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-1)" "unprognostic (2.61e-3)" 26.5 46.1 42.8 28.9 50.3 30.2 19.0 32.6 90.0 26.5 27.6 24.9 14.2 29.8 24.3 20.6 63.5 17.7 21.2 54.1 47.4 44.9 32.7 35.7 18.5 29.5 45.7 61.1 22.9 14.3 27.8 23.2 30.8 72.4 21.9 29.2 30.4 24.5 33.7 8.4 30.0 27.4 35.6 25.7 21.7 20.3 26.1 21.0 26.6 17.4 27.0 43.7 31.0 31.9 22.5 49.7 88.0 65.3 22.8 41.2 72.8 119.7 57.0 39.4 75.1 37.3 34.4 53.7 76.8 100.5 90.3 126.0 61.8 35.8 63.5 52.7 65.2 36.3 75.2 68.4 111.7 109.5 58.7 65.4 41.0 44.7 69.1 27.6 58.7 54.9 33.6 45.8 60.0 44.8 122.3 65.3 47.7 26.8 36.0 94.7 49.5 52.4 72.5 60.3 34.7 68.4 39.9 36.1 50.3 69.7 45.5 8.6 40.3 41.3 24.7 39.4 64.5 67.2 49.5 49.1 48.4 42.6 42.7 88.1 54.3 59.8 57.9 112.5 98.2 22.3 30.4 65.3 88.0 37.0 57.2 32.7 22.5 31.8 36.6 49.7 18.8 20.7 28.9 50.3 22.8 62.8 17.6 41.2 72.8 42.8 50.3 32.6 90.0 47.4 44.9 45.7 61.1 72.4 21.0 41.7 37.7 99.1 98.5 166.1 402.1 21.4 81.5 34.8 53.4 101.2 72.6 433.1 303.4 278.9 11.6 112.3 222.3 46.7 180.1 698.3 148.4 67.2 102.6 165.4 366.0 365.5 46.3 103.7 173.5 17.6 138.4 127.2 124.9 317.4 104.7 280.3 240.1 115.6 220.3 200.3 232.1 200.5 123.6 31.0 121.7 178.9 311.6 142.2 136.4 230.0 PGAM2 PGAM-M ENSG00000164708 "Phosphoglycerate mutase 2" P15259 7 44062727-44065587 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "heart muscle: 111.6;skeletal muscle: 379.1;tongue: 119.0" "Group enriched" "Detected in many" 13 "Early spermatids: 421.0;Late spermatids: 1332.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.2;neutrophil: 1.1;plasmacytoid DC: 1.3;T-reg: 1.7" "Group enriched" "Detected in many" 4 "dendritic cells: 1.3;granulocytes: 1.2;T-cells: 1.7" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 39.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA043801, HPA050314, HPA060173" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA 60000000 Nucleoplasm "Nucleoli, Cytosol" "HPA043801: , HPA050314: AB_2732558, HPA060173: AB_2684215" 1.4 0.8 2.0 0.4 2.2 0.4 0.5 6.9 2.1 0.5 0.5 3.6 0.0 0.6 0.5 9.1 6.1 0.6 0.7 111.6 2.1 3.2 0.8 0.4 0.4 0.4 4.2 1.6 0.5 0.6 0.6 1.3 0.4 2.0 1.9 0.4 2.3 7.6 0.5 379.1 0.4 0.4 0.4 3.2 0.5 0.5 16.7 1.1 4.8 1.5 119.0 4.8 0.4 0.0 0.3 1.3 1.2 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.0 4.3 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.3 1.7 0.2 2.0 2.2 6.9 2.1 2.1 3.2 4.2 1.6 2.0 1.1 0.0 0.0 0.5 0.2 1.0 4.3 0.0 0.0 0.0 0.0 0.0 9.8 0.0 68.0 0.0 421.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 22.0 0.0 0.3 1332.7 7.2 0.4 1.7 0.0 0.0 3.8 0.2 0.2 5.6 1.9 4.2 25.8 3.1 30.5 5.6 0.5 0.0 0.0 0.2 0.4 PGAM4 "dJ1000K24.1, PGAM-B, PGAM1, PGAM3" ENSG00000226784 "Phosphoglycerate mutase family member 4" Q8N0Y7 X 77968874-77969638 "Enzymes, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 2.1;Melanocytes: 3.3;Suprabasal keratinocytes: 2.0" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 5.4" "HPA042528, HPA060483" Uncertain Uncertain Nucleoplasm NA NA Nucleoplasm "HPA042528: AB_2678039, HPA060483: AB_2684292" "unprognostic (3.10e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (3.18e-2)" "unprognostic (4.37e-2)" "unprognostic (4.21e-2)" "unprognostic (7.71e-2)" "unprognostic (1.89e-2)" "unprognostic (1.78e-1)" "unprognostic (7.52e-3)" "unprognostic (3.19e-2)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (1.20e-1)" "unprognostic (4.15e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-3)" 0.9 2.1 0.9 2.6 1.5 3.0 0.4 0.8 2.1 1.9 0.6 2.4 1.4 0.7 2.9 1.3 0.0 1.3 1.0 1.5 0.9 1.2 0.4 1.2 1.5 1.0 0.1 0.7 0.7 0.7 0.5 0.7 0.6 0.2 1.1 0.8 2.0 1.3 0.4 1.0 1.3 0.5 0.3 0.7 1.6 1.2 0.7 1.9 3.7 2.4 0.8 1.6 3.5 5.4 3.1 0.3 0.9 0.4 0.0 2.7 0.5 0.1 0.6 0.8 0.0 0.5 0.8 1.5 0.3 0.0 2.3 0.2 0.0 0.8 0.6 0.3 0.0 1.1 0.7 0.0 1.6 0.9 0.4 0.2 0.2 0.0 0.1 0.5 0.3 0.0 0.6 0.8 1.0 2.7 3.9 1.1 0.3 0.8 0.8 1.0 2.0 0.0 0.7 0.1 2.7 0.3 0.0 1.3 0.3 1.0 0.6 0.0 1.0 1.8 1.6 3.1 2.8 1.4 0.7 3.7 1.6 0.5 0.6 2.4 3.7 1.4 2.2 1.1 0.7 1.1 1.3 1.9 0.7 0.6 0.9 1.5 0.8 2.1 0.5 1.6 3.5 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.1 0.0 0.0 0.0 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593276-63660245 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 233.5" "Cell type enhanced" "Detected in many" 5 "Exocrine glandular cells: 209.3;Hepatocytes: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Approved Cytosol NA NA 20000000 Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 17.8 14.1 7.0 4.4 8.3 3.5 9.8 4.4 8.3 6.7 12.9 5.2 4.6 10.6 4.6 7.7 8.8 3.3 8.9 36.9 6.4 5.4 10.0 56.4 7.6 2.7 6.2 6.3 9.7 21.6 12.9 6.2 11.5 8.5 8.7 9.1 5.4 7.9 9.4 233.5 5.3 12.4 8.4 5.6 3.0 5.7 3.0 5.5 3.0 6.0 42.8 6.3 9.4 4.7 12.2 25.9 25.6 17.9 21.1 23.3 16.6 29.8 12.5 4.7 15.5 31.2 23.1 38.3 12.3 16.7 13.4 22.0 10.3 13.9 9.4 25.8 19.0 29.7 7.1 6.5 25.9 15.8 11.5 8.7 19.9 21.2 10.6 25.8 17.4 1.1 29.1 16.7 15.6 24.8 36.0 8.0 9.8 0.0 12.6 21.5 1.8 5.0 9.6 21.4 0.9 20.1 7.1 22.0 3.0 19.5 9.4 2.8 18.4 26.9 28.2 41.0 22.9 8.8 6.6 0.7 19.9 10.2 17.6 10.4 8.0 11.7 15.4 32.5 15.3 8.5 20.5 17.9 25.6 23.3 12.0 18.6 12.2 13.7 17.5 25.9 6.9 12.5 14.5 21.2 21.1 10.2 7.5 10.6 16.6 7.0 8.3 4.4 8.3 6.4 5.4 6.2 6.3 8.5 5.5 86.4 31.4 19.9 24.0 15.9 8.1 140.8 50.9 14.7 10.3 15.7 9.8 71.5 74.6 42.0 24.0 10.7 74.3 0.0 209.3 136.9 28.0 18.3 4.7 186.6 22.2 0.0 12.6 16.0 18.3 5.2 20.4 10.7 25.3 32.5 40.1 54.2 92.3 23.0 35.7 59.8 10.7 12.9 17.9 4.7 7.5 15.8 49.2 21.8 71.1 13.6 PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826633-37862937 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Muller glia cells: 345.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments" NA NA 1900000 "Intermediate filaments" "HPA040676: AB_2677076" "unprognostic (3.11e-2)" "unprognostic (1.01e-2)" "prognostic favorable (2.14e-5)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (5.44e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-3)" "unprognostic (5.32e-2)" "unprognostic (7.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.22e-2)" "unprognostic (6.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (9.97e-2)" "unprognostic (1.02e-1)" 11.2 10.8 7.7 11.6 5.9 7.5 13.5 9.8 5.7 14.7 10.3 4.2 6.5 6.1 15.0 7.6 41.3 7.0 11.0 8.3 7.1 4.0 11.1 13.3 7.5 13.2 4.4 5.7 10.0 9.0 9.5 6.4 27.9 10.4 11.1 8.4 6.8 11.0 5.0 2.4 17.7 8.6 12.2 6.9 13.4 9.0 9.0 3.9 17.3 8.8 31.7 22.9 13.6 18.9 4.5 15.3 30.8 13.1 13.2 7.0 7.2 11.7 4.1 6.3 6.7 4.7 5.3 8.3 14.2 8.4 11.7 12.0 7.2 8.6 15.5 7.1 7.7 15.6 6.1 15.3 13.3 29.8 9.9 8.8 17.0 6.9 5.1 10.3 17.8 11.9 7.7 16.1 9.5 8.6 7.3 18.6 13.7 22.1 2.8 10.2 6.2 20.3 21.1 7.3 8.5 6.4 15.5 10.0 6.4 7.2 22.7 13.3 4.5 7.1 10.5 4.9 9.1 9.1 19.2 16.2 8.8 10.8 11.8 28.8 6.3 16.4 17.6 4.6 23.4 14.6 8.0 13.1 30.8 4.9 10.5 5.8 4.5 4.1 5.6 15.3 2.8 4.0 5.0 16.3 13.2 8.0 3.4 7.0 7.2 7.7 5.9 9.8 5.7 7.1 4.0 4.4 5.7 10.4 3.9 0.0 8.0 10.3 13.2 13.1 5.8 4.5 7.6 5.3 4.5 3.5 0.0 26.6 5.0 13.0 0.8 25.5 7.9 0.0 10.4 30.7 6.7 18.4 12.7 7.3 33.4 6.4 6.9 44.8 19.6 0.9 7.8 24.9 5.0 52.3 9.0 345.3 11.4 3.5 9.2 7.4 13.5 12.9 23.7 0.7 0.5 28.1 66.7 12.9 12.3 17.9 PGM3 "AGM1, DKFZP434B187, PAGM" ENSG00000013375 "Phosphoglucomutase 3" O95394 6 83161150-83193936 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004998, HPA029759, HPA029760" Enhanced Approved Nucleoplasm,Cytosol NA NA 73000 "Nucleoplasm, Cytosol" "CAB004998: AB_425591, HPA029759: AB_10600305, HPA029760: AB_10601109" "prognostic unfavorable (8.78e-4)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.45e-2)" "unprognostic (3.03e-2)" "unprognostic (1.51e-2)" "unprognostic (4.04e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.96e-4)" "unprognostic (4.00e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (2.21e-1)" "unprognostic (7.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.22e-3)" 15.5 16.7 11.2 10.4 13.7 4.8 12.3 19.1 13.3 15.4 10.1 9.0 30.7 8.9 10.6 26.2 10.3 8.8 14.2 12.2 11.0 8.6 12.2 44.9 13.4 6.3 13.5 9.9 15.5 36.3 9.3 36.2 27.6 18.1 30.9 13.7 7.4 29.2 23.4 5.5 7.5 11.6 11.1 9.7 8.1 14.4 16.8 11.3 4.0 14.9 7.6 8.7 11.1 10.0 8.2 7.4 11.1 6.5 5.3 8.7 3.9 10.1 6.8 13.1 15.6 21.3 22.8 15.2 34.8 25.3 16.9 26.6 17.5 4.8 5.4 7.4 34.8 17.2 6.5 11.9 14.6 32.4 4.0 11.6 6.9 13.3 29.2 24.2 6.7 3.4 14.4 12.1 29.7 37.7 17.1 19.9 3.7 22.5 5.9 18.2 10.6 1.1 4.4 5.8 9.1 9.3 4.7 29.3 3.1 13.1 10.1 5.2 8.2 10.0 9.0 7.0 20.5 7.8 7.5 28.9 11.6 6.4 23.3 18.7 11.5 4.4 3.8 9.1 5.4 18.2 11.1 6.4 3.8 5.0 6.0 6.7 8.2 5.2 6.2 5.5 5.0 8.7 8.2 2.7 5.3 6.5 7.4 3.6 3.9 11.2 13.7 19.1 13.3 11.0 8.6 13.5 9.9 18.1 11.3 26.8 20.1 3.7 21.9 14.1 16.1 5.2 20.4 12.0 28.4 10.4 9.8 27.6 6.6 29.3 40.4 10.8 14.0 23.3 43.3 56.1 40.5 76.0 4.7 30.5 15.6 7.9 15.4 16.5 4.7 15.6 31.1 8.3 10.1 12.6 25.8 25.2 36.6 17.5 17.3 18.1 20.4 6.5 18.6 54.3 31.1 13.7 53.9 7.5 15.5 17.9 PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849682 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.2" "Cell type enhanced" "Detected in all" 7 "Late spermatids: 571.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 30000 Nucleoplasm Cytosol "CAB004528: AB_628132, CAB009326: AB_2237080, HPA068650: AB_2686014, HPA070887: " "unprognostic (2.54e-1)" "unprognostic (6.14e-3)" "unprognostic (6.50e-2)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (6.50e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (2.67e-1)" "unprognostic (7.23e-3)" "prognostic favorable (3.25e-4)" "unprognostic (9.43e-2)" "prognostic favorable (7.80e-5)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.21e-2)" 24.5 36.3 40.0 18.7 38.8 25.6 9.3 27.4 66.0 9.2 15.8 18.1 8.5 22.9 14.0 8.3 11.3 16.4 10.1 25.9 38.0 35.2 17.4 14.5 13.2 14.8 38.7 37.2 13.9 21.1 9.5 13.6 13.3 57.3 23.2 6.5 14.1 21.3 15.7 50.2 10.2 21.7 11.1 19.6 15.4 19.6 24.8 15.0 19.7 9.9 8.1 9.3 11.1 9.7 36.4 72.8 88.2 44.9 40.7 53.8 46.2 26.2 24.1 18.0 16.7 6.3 5.6 10.6 19.7 8.5 14.7 14.2 22.3 8.4 16.3 31.4 7.3 15.3 13.5 12.4 11.9 4.7 34.7 52.6 42.4 29.6 19.2 10.3 19.7 24.9 7.7 8.0 9.5 4.5 11.0 11.9 29.3 19.1 24.8 8.8 18.4 29.9 77.2 17.2 11.0 37.1 27.4 18.7 27.3 10.5 12.9 22.7 26.7 19.0 9.5 22.0 7.7 12.2 23.7 20.1 20.4 16.3 31.5 31.5 32.1 30.1 21.9 21.7 25.3 25.0 52.2 43.4 88.2 42.0 44.9 39.2 35.6 41.5 42.1 39.7 36.4 33.1 37.2 26.8 40.7 41.7 72.8 53.8 46.2 40.0 38.8 27.4 66.0 38.0 35.2 38.7 37.2 57.3 15.0 26.8 21.5 49.1 53.7 42.8 68.5 65.3 43.3 56.2 14.8 59.3 11.8 107.3 139.3 95.7 197.0 54.9 69.5 46.7 95.4 80.4 81.4 55.2 63.4 41.4 123.0 57.2 95.8 47.3 50.0 571.0 83.4 67.4 118.1 174.1 57.9 60.8 85.6 73.7 122.0 109.4 50.6 64.7 97.1 136.8 72.0 57.6 46.0 94.4 62.6 47.8 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: AB_2682503, HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favorable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favorable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favorable (2.66e-4)" 14.4 11.3 15.0 8.0 14.7 6.1 18.8 10.7 16.2 9.7 9.7 8.4 6.7 9.5 11.6 19.3 8.9 8.7 30.7 11.2 15.2 12.2 15.6 23.2 7.9 7.9 12.9 11.0 12.7 8.1 8.0 9.2 9.8 10.0 10.4 11.1 6.6 30.7 37.1 68.7 7.3 9.6 9.2 12.4 16.7 9.3 4.7 6.9 9.7 12.9 40.1 9.1 7.8 9.2 28.9 26.8 23.4 23.6 22.4 33.4 22.7 15.4 18.1 19.0 12.9 13.0 10.9 10.1 10.6 12.2 13.0 13.4 9.1 11.5 4.6 31.0 10.9 17.6 11.0 16.8 18.6 16.1 11.7 37.8 7.9 21.6 23.9 7.2 12.5 6.7 7.3 10.3 14.2 4.9 14.7 13.2 14.2 13.3 20.6 9.7 18.7 10.9 21.1 13.5 17.6 16.4 10.9 15.1 13.7 16.5 10.8 12.2 21.7 12.4 5.8 10.9 14.6 9.0 11.5 13.2 5.9 9.1 16.2 7.7 7.1 7.6 7.7 17.0 12.6 6.4 21.9 23.3 23.4 26.8 23.6 26.4 28.9 28.3 25.5 22.8 26.4 29.3 29.4 9.7 22.4 21.8 26.8 33.4 22.7 15.0 14.7 10.7 16.2 15.2 12.2 12.9 11.0 10.0 6.9 62.5 35.0 52.8 54.1 38.4 26.9 74.7 81.5 84.3 51.2 113.4 7.9 137.4 154.2 102.6 10.6 70.5 117.6 23.3 102.2 92.0 70.9 50.1 55.5 238.7 95.4 27.0 88.9 80.4 73.2 6.2 69.0 61.7 57.3 68.5 76.9 55.6 124.5 101.7 76.4 218.0 33.7 84.1 78.3 14.4 39.1 40.9 100.9 62.3 82.1 54.0 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576894-41589890 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 20.8 25.1 24.3 15.2 28.8 15.3 15.0 15.5 27.9 24.7 29.5 12.6 14.1 25.3 12.1 20.1 36.5 24.8 14.7 17.7 19.6 20.6 32.8 32.2 21.7 10.8 20.3 25.5 34.8 30.5 7.7 8.7 9.7 17.8 13.7 13.9 11.8 13.0 17.3 6.6 13.6 22.0 14.3 15.2 6.0 24.5 27.6 13.2 8.8 8.9 12.7 14.7 15.2 13.2 10.6 13.2 24.5 12.7 6.8 27.1 10.3 5.3 9.8 6.7 14.4 19.4 30.2 7.8 21.1 24.1 19.5 21.5 7.8 5.1 5.0 7.1 25.1 14.0 8.0 8.8 13.6 11.0 10.3 13.5 1.2 12.3 16.4 30.8 7.4 8.1 25.1 13.2 20.1 8.5 21.7 3.1 8.1 5.5 17.8 26.4 14.0 5.6 10.7 2.1 25.2 13.2 4.3 7.2 10.3 8.2 5.7 1.9 3.8 17.2 6.2 25.2 5.5 7.0 8.2 2.4 22.0 12.1 20.5 10.8 11.2 10.8 7.9 24.6 6.2 13.2 9.6 12.7 24.5 16.3 10.2 13.8 10.4 16.8 13.8 13.2 10.6 18.3 12.9 16.6 6.8 12.0 5.0 27.1 10.3 24.3 28.8 15.5 27.9 19.6 20.6 20.3 25.5 17.8 13.2 32.8 81.3 24.1 11.2 13.2 18.0 10.2 61.1 46.8 36.4 33.2 5.9 49.2 91.2 22.6 11.4 5.8 103.9 23.3 9.6 78.2 28.7 9.3 3.5 75.7 29.4 27.0 46.8 10.4 11.3 10.8 25.9 14.0 42.2 25.2 41.2 49.6 15.1 112.2 28.7 109.0 19.6 38.8 39.8 45.9 10.4 12.3 54.6 20.3 47.6 5.5 PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8849331 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Club cells: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "basophil: 52.2" "Lineage enriched" "Detected in all" 10 "granulocytes: 52.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040852, HPA063649" Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA040852: AB_10794069, HPA063649: AB_2685074" "unprognostic (8.62e-3)" "unprognostic (8.00e-3)" "prognostic favorable (1.04e-4)" "unprognostic (3.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.98e-2)" "unprognostic (6.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (5.14e-3)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (6.89e-2)" "unprognostic (5.02e-2)" 14.8 13.1 6.8 15.4 9.0 4.3 13.6 8.2 8.2 11.4 19.4 7.0 11.6 18.9 9.7 13.1 22.7 10.0 13.9 10.7 4.7 2.9 14.6 43.3 11.8 11.2 6.6 4.3 7.8 40.4 7.8 28.3 19.9 6.6 12.0 20.4 8.8 21.2 13.5 12.5 13.2 19.6 9.5 5.7 12.0 15.2 9.7 7.8 7.6 10.0 12.0 22.0 10.5 12.2 2.9 3.5 52.2 4.9 1.6 3.6 3.0 10.8 24.3 5.4 14.1 9.6 15.2 12.0 17.0 20.6 17.1 18.5 18.2 13.5 17.4 7.2 29.7 9.0 15.1 11.0 20.8 17.5 12.9 12.9 5.7 14.7 31.0 18.3 15.2 13.8 22.7 14.8 18.2 16.8 7.9 17.4 10.8 7.8 17.0 11.3 28.5 15.6 14.0 22.9 25.4 15.8 19.8 12.0 34.6 19.0 19.3 10.3 19.3 14.0 30.9 10.2 9.0 20.1 13.4 20.1 12.3 13.9 33.2 16.6 21.0 17.6 21.9 10.3 19.2 16.3 52.2 4.9 0.9 2.5 3.7 3.6 2.9 2.2 3.2 3.5 2.4 2.5 2.4 7.8 1.6 2.3 3.2 1.6 3.0 6.8 9.0 8.2 8.2 4.7 2.9 6.6 4.3 6.6 7.8 14.9 17.9 9.8 6.8 3.4 4.8 2.4 5.1 26.8 46.6 0.0 13.7 7.4 8.3 10.9 0.2 4.5 10.2 23.3 24.6 9.5 5.4 9.5 22.0 11.3 5.1 1.6 7.5 3.7 6.0 0.6 5.8 6.3 1.7 8.2 11.5 2.3 17.8 10.2 2.1 10.0 8.9 0.0 5.2 1.6 3.1 3.6 8.9 5.1 9.2 11.3 PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" NA NA 420000000 "CAB004655: AB_425607, HPA058345: AB_2683685" "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" 92.0 90.3 147.0 80.4 124.3 105.9 169.0 88.9 148.0 111.3 143.5 81.6 52.9 73.9 74.8 125.1 176.5 76.3 80.4 60.2 132.0 121.9 149.2 214.3 95.4 137.1 123.2 88.3 74.2 103.2 93.1 58.3 96.2 142.5 83.0 149.1 68.1 84.7 102.3 68.4 114.7 105.1 113.9 120.8 137.0 73.1 62.4 59.8 228.2 130.2 123.4 191.2 94.3 93.1 129.8 158.5 35.0 83.1 76.0 117.7 180.3 85.4 114.8 145.8 105.8 122.2 185.9 48.1 125.3 196.9 240.8 236.3 127.3 131.1 193.3 64.6 159.6 265.6 116.9 187.4 240.0 222.2 110.5 136.7 78.1 132.3 121.2 99.2 158.2 81.5 136.0 164.8 170.6 187.5 123.7 244.4 134.0 160.4 156.3 247.6 121.7 173.3 280.1 166.4 289.1 158.3 124.5 88.3 245.9 326.5 120.9 109.2 90.5 105.6 303.0 82.3 181.0 162.4 216.0 108.6 124.1 119.7 83.0 164.2 114.1 225.3 326.2 108.2 180.1 187.2 23.4 74.5 35.0 94.9 83.1 102.0 129.8 97.0 97.1 134.8 103.9 80.3 88.2 9.2 76.0 77.7 158.5 117.7 180.3 147.0 124.3 88.9 148.0 132.0 121.9 123.2 88.3 142.5 59.8 738.4 649.6 630.7 788.0 769.8 81.7 43.6 573.3 655.8 728.0 572.3 17.7 772.4 1198.7 1053.9 61.2 614.7 668.4 210.2 1054.9 1359.4 612.8 450.0 590.8 641.5 1374.9 104.9 508.7 685.7 1073.8 53.8 539.0 844.5 656.3 1506.8 976.8 169.9 1130.2 533.1 576.3 1183.4 66.5 388.1 545.9 364.4 288.3 865.6 509.5 657.9 1124.8 784.3 PPIAL4A "COAS2, PPIAL4, PPIAL4B" ENSG00000263353 "Peptidylprolyl isomerase A like 4A" Q9Y536 1 120889746-120890405 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 3.5;intestine: 1.6" "Cell type enriched" "Detected in single" 10 "Distal tubular cells: 1.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 3.8;NB-4: 4.6;SK-BR-3: 4.7" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (3.49e-3)" "unprognostic (2.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-2)" "unprognostic (1.74e-1)" 0.3 0.8 1.0 1.4 0.2 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 3.0 3.2 0.6 1.6 2.2 2.4 3.5 0.9 0.0 0.1 1.4 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 1.0 0.7 0.2 0.0 0.3 1.8 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.2 3.8 0.3 0.6 1.7 4.6 2.5 0.0 0.0 0.8 1.5 1.9 0.0 0.0 1.0 0.3 0.3 4.7 0.4 0.1 3.1 2.5 0.7 3.0 1.2 2.9 1.7 1.4 0.9 2.5 2.6 1.6 3.2 0.2 1.6 0.6 1.4 1.2 1.4 3.0 2.3 2.4 3.1 2.2 1.5 2.4 0.0 2.2 1.2 3.2 2.4 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4C ENSG00000263464 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583865-149584464 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 10.9;intestine: 5.5" "Cell type enriched" "Detected in single" 16 "Cardiomyocytes: 1.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 14.4;THP-1: 16.9" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.25e-1)" 0.0 3.3 2.7 0.1 0.0 1.5 0.0 0.8 5.5 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 2.9 0.2 0.0 0.9 0.7 0.3 0.0 0.0 0.0 0.2 0.5 2.9 0.0 1.4 0.9 0.0 0.0 0.3 0.0 9.1 9.7 1.9 6.0 4.6 7.8 10.9 3.6 0.3 0.4 3.1 0.1 0.3 2.0 0.6 0.4 1.0 0.7 0.0 4.8 1.3 2.1 0.0 2.5 3.9 0.0 0.2 0.6 3.5 0.0 0.5 0.0 0.0 0.1 2.0 1.9 0.1 0.5 0.6 0.3 0.0 0.0 0.5 0.9 5.4 0.7 0.4 5.3 14.4 6.2 1.0 0.1 5.3 0.0 9.0 0.2 0.0 4.0 5.5 1.1 11.3 6.2 0.3 5.3 16.9 1.3 3.6 5.6 3.3 8.2 4.2 5.6 9.2 3.9 4.6 7.8 0.9 4.3 1.9 5.4 6.0 6.0 9.1 6.1 5.7 9.4 7.2 5.0 5.9 0.0 4.6 5.3 9.7 7.8 10.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4D ENSG00000256374 "Peptidylprolyl isomerase A like 4D" F5H284 1 145241630-145242124 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Group enriched" "Detected in some" 4 "blood: 5.4;brain: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 2.1;NB-4: 1.9;RPMI-8226: 1.0;SK-MEL-30: 1.8;THP-1: 1.5" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (9.32e-2)" "unprognostic (1.33e-1)" "unprognostic (3.05e-2)" 0.0 0.0 0.5 0.0 0.7 0.0 0.0 3.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.6 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.5 3.8 0.7 3.7 1.8 4.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.9 0.4 0.0 0.0 0.0 1.8 0.0 0.6 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.7 1.4 0.3 1.2 3.7 1.4 4.5 2.7 1.7 3.6 3.1 2.8 3.5 0.0 1.8 1.8 3.8 4.1 5.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 PPIAL4E ENSG00000271567 "Peptidylprolyl isomerase A like 4E" A0A075B759 1 144372875-144373659 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 3.4;bone marrow: 2.7;skeletal muscle: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;HL-60: 1.2;hTERT-RPE1: 1.9;NB-4: 1.4;SK-BR-3: 2.0;TIME: 1.9" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (6.97e-2)" "unprognostic (5.22e-2)" "unprognostic (2.28e-1)" 0.0 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 1.9 2.0 3.4 2.9 0.6 0.6 0.5 0.4 0.1 0.0 0.0 0.4 0.2 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.3 1.0 0.0 0.0 1.9 0.1 0.5 0.3 0.0 0.6 0.4 0.2 0.0 0.2 0.0 0.0 2.0 1.0 2.9 0.5 1.9 1.3 1.6 1.3 0.5 1.7 0.5 0.5 1.9 3.4 1.5 0.6 0.8 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4F ENSG00000279782 "Peptidylprolyl isomerase A like 4F" P0DN26 1 144592868-144593527 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (1.08e-1)" "unprognostic (2.22e-2)" "unprognostic (2.02e-1)" 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4G ENSG00000236334 "Peptidylprolyl isomerase A like 4G" P0DN37 1 148479824-148483679 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 6.9;skeletal muscle: 6.8" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 6.1;Suprabasal keratinocytes: 10.9;T-cells: 6.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (2.17e-3)" "unprognostic (3.63e-1)" "unprognostic (4.83e-1)" "unprognostic (2.26e-1)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (3.95e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" 0.2 0.1 1.3 0.7 1.8 1.3 0.3 6.9 1.2 0.1 0.2 0.5 0.4 1.0 0.3 0.1 0.3 0.2 0.9 1.1 0.1 0.2 0.2 1.1 0.5 0.4 0.0 0.1 0.3 0.1 0.2 0.3 0.4 0.0 6.8 0.8 0.7 0.0 0.4 2.7 0.5 0.5 0.4 0.3 0.0 0.0 2.2 0.6 2.4 0.8 2.4 3.2 0.2 0.8 1.1 0.5 1.7 0.2 0.3 1.3 0.3 0.3 0.1 0.1 1.3 0.9 1.2 0.8 0.3 0.2 1.0 0.1 0.2 0.2 0.5 0.7 1.2 2.4 1.0 0.1 1.5 1.2 0.2 1.8 0.1 0.3 0.3 0.2 1.0 0.7 1.8 0.0 0.9 0.8 2.5 1.1 0.1 0.3 0.6 0.3 0.8 0.3 1.3 0.7 1.0 1.0 0.7 0.4 0.9 1.2 1.4 0.8 0.9 0.9 1.4 0.7 1.4 1.2 1.0 0.7 1.0 0.9 2.2 0.4 1.0 3.2 0.4 2.4 0.9 1.5 1.7 0.3 2.2 1.6 2.8 2.4 2.4 0.8 0.6 0.5 0.2 0.0 1.1 0.0 0.4 6.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 1.1 0.4 0.2 1.6 0.0 0.6 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 10.9 0.1 6.7 0.0 0.1 PPIB "CYPB, OI9" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155812-64163205 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Isomerase, Rotamase" "Disease mutation, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" No No 120000000 "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 56.9 64.3 23.9 49.3 26.9 54.9 48.1 15.1 32.1 75.3 44.1 35.4 102.8 42.0 64.2 106.9 48.0 54.8 58.1 44.5 23.8 27.3 89.5 285.9 57.2 63.8 29.7 19.6 67.5 193.7 26.7 71.8 120.2 27.5 51.0 47.7 36.2 123.3 95.4 19.5 33.1 57.5 54.3 30.7 78.0 47.7 27.2 29.5 53.7 154.3 45.7 69.1 49.2 51.7 63.5 191.6 41.0 51.1 44.9 71.6 87.1 39.7 50.0 45.2 102.6 158.3 91.9 39.8 94.9 124.7 75.2 89.4 71.9 73.8 38.0 77.2 147.0 76.4 64.9 82.5 63.8 38.8 24.1 31.1 53.6 55.2 94.1 166.0 53.4 48.5 84.6 68.8 43.8 106.9 93.2 90.8 18.2 37.3 132.4 56.9 63.5 16.3 82.0 39.4 110.7 32.2 31.2 48.0 193.7 78.0 62.0 25.6 40.3 43.5 74.8 69.1 69.6 44.7 163.5 55.8 75.2 62.3 42.0 64.0 71.9 69.6 39.9 70.2 86.1 75.0 41.0 51.1 33.9 71.6 39.2 71.5 63.5 50.5 58.1 67.4 38.0 33.0 44.2 25.5 44.9 25.2 191.6 40.1 87.1 23.9 26.9 15.1 32.1 23.8 27.3 29.7 19.6 27.5 29.5 116.1 168.3 153.4 361.8 142.3 26.7 0.7 280.2 128.5 194.5 258.2 29.5 546.5 76.3 534.3 16.2 209.5 301.3 70.0 495.6 1107.3 581.4 486.2 176.7 431.7 566.9 42.9 284.9 371.4 213.7 20.8 422.5 284.2 266.6 285.9 313.7 126.6 471.5 326.7 369.5 231.9 33.9 226.4 234.9 37.1 72.8 126.6 935.7 261.7 353.5 357.9 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Fibroblasts: 273.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 58.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 5700000 "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 22.5 13.7 3.3 10.8 3.6 0.0 29.9 1.6 4.2 24.3 30.0 3.6 26.6 15.7 20.4 32.7 35.5 9.0 25.8 43.7 4.0 2.7 27.4 24.0 16.3 9.0 3.7 2.1 13.3 24.3 8.7 5.8 28.3 10.0 17.8 22.0 5.3 25.9 18.0 18.4 12.0 35.2 37.9 5.4 8.9 13.5 8.0 3.2 2.5 42.7 29.6 12.9 31.5 21.5 0.0 1.1 0.0 0.1 0.0 0.3 0.0 4.7 4.1 1.6 33.9 58.9 27.1 6.7 13.4 10.5 7.0 14.4 6.8 31.8 0.0 23.8 35.9 21.0 5.3 4.6 16.8 5.6 0.0 8.2 6.7 15.4 7.8 15.1 0.0 3.7 16.9 12.9 8.1 8.6 12.6 14.4 0.0 1.8 0.0 5.0 27.9 0.0 0.0 2.9 29.2 7.2 0.0 3.6 0.0 22.0 16.3 2.1 3.7 26.2 12.7 2.8 20.5 17.9 15.0 15.9 13.4 8.4 4.6 5.7 0.0 0.0 0.0 11.6 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 3.3 3.6 1.6 4.2 4.0 2.7 3.7 2.1 10.0 3.2 29.8 13.9 0.9 43.9 42.1 13.9 38.9 53.5 25.4 14.8 69.8 3.9 50.1 24.9 171.5 1.0 100.3 130.1 0.0 111.8 45.8 273.0 38.3 1.1 48.9 36.5 0.0 12.2 66.9 4.8 3.5 104.2 7.7 30.4 5.4 148.2 1.8 98.5 178.9 94.0 64.2 3.8 38.8 61.4 26.6 14.1 43.2 20.9 2.2 72.5 66.5 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709134-158723396 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 16.8 25.8 20.1 15.5 21.4 14.9 22.3 26.7 26.8 12.6 16.8 14.4 18.2 33.4 14.6 13.6 16.5 15.4 13.0 28.8 19.4 22.1 21.5 45.3 11.0 17.4 22.6 18.9 14.6 17.5 11.3 30.3 14.5 26.0 16.1 14.2 9.1 15.4 13.7 53.3 24.0 29.2 13.1 22.7 16.5 15.5 16.9 23.4 22.7 21.7 16.0 16.8 15.4 55.0 15.6 17.2 33.4 22.2 23.9 24.4 17.1 15.5 14.5 14.6 20.0 21.7 16.3 22.1 15.4 8.4 14.2 10.8 18.8 10.7 16.5 6.9 14.3 22.3 12.0 44.2 17.7 17.3 54.5 15.4 29.5 13.1 25.8 16.8 18.4 22.2 10.3 14.4 12.1 18.2 18.4 15.4 28.2 36.7 29.4 15.8 14.9 26.4 16.7 20.1 25.5 19.4 12.0 7.2 14.1 15.6 7.8 24.7 16.6 11.5 24.0 21.9 22.1 11.0 17.7 14.9 14.2 16.0 15.6 20.3 16.9 35.0 21.0 18.1 20.0 14.2 33.4 15.3 33.2 21.2 22.2 24.4 14.6 20.7 19.6 16.7 15.6 21.5 22.0 20.9 23.9 22.0 17.2 22.4 17.1 20.1 21.4 26.7 26.8 19.4 22.1 22.6 18.9 26.0 23.4 6.0 12.0 18.8 25.3 9.0 24.6 50.0 28.1 76.3 33.0 26.2 21.6 33.4 31.5 34.8 23.6 25.6 19.0 0.0 20.1 39.2 21.3 25.8 31.2 16.1 36.7 71.5 18.8 18.4 11.0 15.7 19.0 21.8 13.5 63.1 22.9 21.7 26.7 21.6 21.2 24.9 25.3 6.5 30.2 78.8 76.3 10.3 39.8 27.4 24.2 17.2 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 19.3 23.8 23.7 24.3 22.5 18.6 25.7 25.9 36.1 25.5 28.1 35.6 22.2 19.7 30.6 26.5 26.0 34.7 21.1 27.1 22.3 22.1 25.2 29.8 20.6 25.9 26.3 20.5 35.5 42.1 27.4 23.6 21.9 24.9 26.1 22.7 26.9 30.7 28.9 29.6 21.7 23.2 34.2 25.6 25.7 23.9 38.8 20.2 22.8 33.7 21.9 33.9 31.5 22.6 43.3 31.6 14.1 27.2 49.0 46.9 44.2 9.8 17.1 15.7 12.6 17.5 15.6 8.3 17.0 17.1 26.0 24.5 21.3 29.2 28.0 24.1 19.0 16.7 15.1 21.5 25.2 24.8 18.1 23.2 30.9 19.8 6.4 24.0 27.8 16.9 14.1 23.1 24.4 9.0 18.9 23.3 25.0 31.3 19.6 18.9 17.7 12.8 22.6 18.8 23.3 19.1 19.0 11.8 15.9 19.6 18.4 22.4 17.9 17.8 14.5 12.3 19.4 18.2 73.1 15.1 16.3 18.1 20.2 26.0 26.9 26.9 19.4 11.3 35.9 25.6 11.6 27.1 14.1 38.3 27.0 37.0 43.3 39.7 38.2 31.6 39.8 46.9 38.9 2.2 49.0 27.2 28.5 40.0 44.2 23.7 22.5 25.9 36.1 22.3 22.1 26.3 20.5 24.9 20.2 29.8 27.1 41.2 35.7 22.0 24.9 29.6 17.8 64.3 56.9 31.4 13.7 54.2 56.3 49.6 25.8 24.5 23.9 0.0 42.1 51.6 34.0 28.9 54.3 27.6 48.7 22.3 27.6 25.8 36.1 47.7 27.6 34.0 37.1 53.3 28.0 35.4 38.6 28.1 42.5 54.9 25.9 58.2 41.0 62.7 44.8 23.1 29.1 40.6 33.0 29.5 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 32.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 27000000 Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 16.5 76.2 12.1 15.7 18.8 52.0 16.9 7.1 21.3 8.3 18.1 27.1 13.2 13.3 5.2 7.6 21.0 8.8 10.0 36.5 13.0 14.5 21.0 73.1 9.4 19.4 23.3 16.6 7.2 42.0 12.0 6.2 11.3 25.2 6.6 19.9 7.5 12.7 21.9 44.4 22.5 11.1 9.9 28.0 19.6 34.0 20.8 18.0 8.8 10.0 73.9 19.8 12.5 11.0 8.0 18.6 32.8 14.9 3.6 5.0 6.5 35.6 15.2 10.7 21.0 10.0 13.0 13.7 20.8 27.3 45.8 43.4 35.5 17.3 37.1 11.6 14.6 32.6 21.4 33.1 19.4 71.5 11.7 31.2 58.1 14.9 62.4 17.0 40.0 13.8 30.4 13.9 45.4 45.5 14.9 8.0 14.6 56.5 45.8 15.5 18.3 10.3 33.5 9.0 16.4 84.5 17.8 16.5 19.0 17.8 33.3 21.3 15.8 10.7 43.3 16.0 7.3 18.9 30.9 7.2 20.1 18.3 23.6 40.0 21.3 21.6 30.0 19.9 52.1 5.4 5.1 14.9 7.3 4.7 11.4 5.0 8.0 4.2 4.3 18.6 3.9 3.8 3.7 32.8 3.6 4.1 2.3 4.2 6.5 12.1 18.8 7.1 21.3 13.0 14.5 23.3 16.6 25.2 18.0 6.0 5.0 34.4 26.4 37.8 4.4 106.2 15.3 12.0 9.1 12.2 5.9 70.1 77.9 37.7 11.0 13.8 22.2 46.7 24.2 113.4 24.0 17.4 13.8 70.1 83.0 7.9 20.7 8.6 32.4 11.1 5.8 60.2 33.7 33.3 62.3 9.9 40.0 17.5 5.6 31.1 4.9 19.4 24.1 7.0 22.2 33.0 119.0 17.5 63.7 28.5 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584340-169641406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.2 25.3 28.5 23.8 45.3 39.2 26.7 45.0 40.7 33.1 27.1 14.6 26.0 25.3 27.1 28.1 29.4 24.3 21.2 24.2 30.0 20.3 26.0 41.1 25.5 30.4 27.7 35.9 29.5 22.8 39.4 56.7 26.0 38.0 29.3 23.9 13.8 28.6 28.8 27.8 24.5 30.8 31.9 39.7 29.7 24.1 19.8 33.7 24.1 28.4 22.6 29.9 37.4 27.6 36.4 23.7 41.7 24.7 18.7 29.6 13.3 19.5 9.3 26.3 14.4 14.6 17.9 24.8 22.4 16.8 16.5 17.1 25.4 22.6 33.7 20.6 16.1 20.7 18.8 20.6 18.3 24.5 23.4 16.6 50.7 13.9 30.9 14.1 47.7 22.6 15.0 20.7 22.4 25.2 15.7 18.1 20.6 48.9 28.2 18.8 15.8 35.2 29.3 37.7 15.9 9.5 32.4 26.3 32.9 20.4 29.4 23.0 15.2 24.0 17.9 24.3 21.1 16.7 27.6 20.8 21.6 16.5 14.4 18.3 16.4 23.6 47.1 15.9 25.6 19.7 20.7 20.0 29.9 20.3 20.1 23.2 27.6 27.0 23.8 14.9 36.4 29.6 23.7 41.7 18.7 24.7 23.7 22.9 13.3 28.5 45.3 45.0 40.7 30.0 20.3 27.7 35.9 38.0 33.7 205.4 160.5 152.0 169.4 134.5 178.8 130.1 61.1 132.5 155.8 89.0 51.1 146.0 68.0 90.9 6.8 121.2 97.1 70.0 90.5 147.9 117.4 133.0 172.3 157.2 134.3 208.2 100.6 106.2 118.2 8.4 131.5 135.1 104.6 124.4 115.6 123.1 82.2 108.7 137.9 99.6 103.2 161.7 154.6 225.0 148.0 150.9 171.9 152.4 132.6 136.1 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658425-42676758 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved NA NA "HPA059019: AB_2683885" "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 17.5 19.7 20.4 35.7 19.6 40.7 21.4 23.9 23.3 19.5 24.0 20.9 14.7 18.0 29.8 24.2 29.6 19.2 14.4 21.2 18.0 16.1 17.5 13.6 17.8 31.0 15.8 19.9 22.0 17.7 7.0 15.2 24.6 17.2 17.1 26.5 19.2 24.4 18.8 18.4 20.9 20.7 20.8 15.0 27.2 18.0 21.1 18.6 39.7 26.9 28.1 36.8 15.3 20.3 20.0 14.9 16.8 12.3 18.5 26.3 14.0 19.3 12.5 15.8 22.1 5.2 9.9 21.3 13.2 9.3 24.7 22.6 19.7 22.1 32.0 16.6 9.7 12.0 15.7 28.7 20.2 26.0 26.9 23.2 30.4 23.0 18.2 4.5 58.2 17.8 6.4 10.7 23.0 18.0 9.6 11.5 31.0 37.6 18.2 12.1 16.2 45.1 82.0 38.8 18.6 15.0 25.3 29.4 28.4 11.8 12.6 12.4 22.5 11.6 19.3 14.5 20.5 10.6 85.3 9.5 10.9 27.9 14.9 31.5 11.8 27.5 58.2 12.2 54.5 17.8 12.6 8.8 16.8 21.0 12.3 19.8 20.0 21.7 23.9 11.7 19.2 22.3 26.3 1.8 18.5 11.2 14.9 20.2 14.0 20.4 19.6 23.9 23.3 18.0 16.1 15.8 19.9 17.2 18.6 17.9 20.2 42.4 37.9 25.6 8.9 12.2 15.3 16.0 14.8 21.0 3.9 53.8 38.1 23.6 19.6 18.3 12.3 0.0 23.0 87.1 17.1 22.2 30.1 9.6 45.9 4.8 20.6 18.4 15.3 7.6 27.0 26.9 15.1 27.9 25.8 14.3 22.0 17.5 20.1 25.0 11.8 19.4 16.9 16.3 29.6 18.7 31.7 41.5 31.9 30.1 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36875024 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Extravillous trophoblasts: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA Nucleoli "HPA062916: AB_2684904" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favorable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 9.0 17.2 15.9 11.1 23.1 7.3 12.3 16.6 18.7 11.1 10.2 13.0 5.7 8.7 13.7 11.7 13.1 17.5 7.5 29.7 13.2 19.8 17.6 34.3 7.5 13.4 15.0 15.5 13.2 36.7 10.6 19.4 16.0 15.3 11.2 13.2 11.0 12.0 12.5 11.7 5.6 8.2 17.4 15.8 10.3 8.5 14.0 11.0 10.2 23.5 13.4 17.4 12.2 8.1 7.7 6.6 1.1 4.4 5.0 15.0 6.9 14.3 11.3 29.9 19.9 4.0 8.5 16.2 14.5 9.7 22.0 18.3 19.8 9.5 22.0 18.4 10.2 29.0 11.6 35.3 24.2 25.2 18.3 29.5 26.0 7.4 26.1 13.4 22.2 10.9 6.3 11.5 16.9 31.6 8.1 19.6 21.3 48.8 10.7 15.8 13.6 26.4 10.2 19.8 27.5 15.3 21.3 26.2 19.7 13.0 10.1 31.8 16.8 9.7 10.4 19.1 23.0 15.2 18.9 11.9 17.0 15.7 12.9 24.2 11.8 30.6 40.1 5.4 41.2 32.3 1.1 3.2 0.8 11.2 4.4 15.0 7.7 9.3 10.7 6.6 6.2 10.5 12.3 0.9 5.0 2.1 5.6 6.8 6.9 15.9 23.1 16.6 18.7 13.2 19.8 15.0 15.5 15.3 11.0 6.0 6.9 6.7 16.2 2.7 14.1 40.3 7.6 20.1 7.9 5.2 3.9 50.9 19.9 22.9 21.9 9.2 2.6 0.0 17.8 54.4 8.4 9.5 10.4 6.8 25.9 15.9 3.5 3.7 2.8 8.5 6.4 9.5 6.8 11.8 8.5 25.1 18.1 7.0 11.7 10.2 10.5 6.5 8.9 14.4 49.0 4.0 21.2 7.5 10.3 8.6 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666009-21700015 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 71.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "HPA035344: AB_10672863, HPA055637: AB_2682869" "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 15.0 21.5 19.4 20.9 24.6 16.6 13.5 24.1 30.9 17.7 17.4 25.3 19.1 18.6 21.8 17.0 22.3 15.7 16.5 20.0 17.2 17.1 21.2 20.3 14.6 23.7 15.6 20.9 16.6 31.4 23.6 30.2 31.4 19.0 19.5 17.6 23.6 22.0 16.5 25.5 17.5 19.1 15.2 15.0 21.3 19.5 18.4 17.6 32.8 27.0 13.6 33.5 17.4 16.2 8.7 11.7 4.8 17.3 12.8 13.2 9.1 6.6 6.9 8.1 8.5 8.3 7.1 7.3 8.7 6.2 10.7 9.2 7.0 4.4 11.5 5.3 9.7 5.4 9.8 10.8 7.5 6.4 7.1 11.1 10.7 6.9 8.3 6.0 16.9 10.1 7.7 6.8 7.6 5.8 6.5 9.2 7.3 71.2 8.3 7.6 10.4 7.6 4.6 7.8 12.4 4.3 9.8 12.0 2.3 5.4 6.7 12.7 6.9 7.9 12.7 2.9 5.0 9.1 5.7 11.1 6.7 11.0 7.9 5.5 9.6 7.0 8.7 7.6 6.4 8.1 1.0 8.6 4.7 9.5 13.9 11.4 7.0 11.1 12.0 11.7 8.7 9.8 8.9 4.8 12.8 17.3 11.1 13.2 9.1 19.4 24.6 24.1 30.9 17.2 17.1 15.6 20.9 19.0 17.6 8.9 25.6 20.6 7.3 2.9 22.7 4.0 30.6 6.7 17.0 14.0 31.4 13.2 11.6 10.6 57.9 5.4 16.9 0.0 14.6 12.4 5.7 12.9 16.2 16.6 13.2 17.5 10.9 11.1 24.4 67.5 11.2 14.4 1.7 10.0 20.5 12.3 15.0 17.3 12.7 7.0 29.8 0.0 4.4 18.6 16.3 5.0 18.5 15.9 18.4 10.3 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 35000 Nucleoplasm Nucleoli "HPA040765: AB_2677125, HPA062187: AB_2684706" "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favorable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 12.4 17.9 18.1 15.5 19.2 24.2 21.1 20.1 20.2 19.4 16.4 18.4 21.1 12.7 17.2 24.3 25.4 19.1 15.9 17.6 17.5 21.8 15.9 19.4 15.9 23.7 20.0 11.8 31.4 16.7 11.9 17.4 15.5 23.0 19.5 16.6 16.3 13.8 15.8 13.4 14.7 15.7 16.8 23.2 20.2 15.7 18.2 13.0 26.3 23.7 19.4 25.5 28.6 13.6 23.4 21.7 18.7 14.1 20.6 20.6 10.7 8.0 7.1 22.1 9.6 17.3 37.2 7.2 12.8 13.9 14.8 15.0 5.2 15.2 7.7 13.6 13.8 17.4 10.6 7.7 15.6 13.3 16.3 18.5 32.5 19.9 35.1 8.9 31.1 16.5 13.5 15.3 12.1 19.1 25.0 9.8 15.3 25.7 18.9 18.8 12.8 23.9 24.8 13.5 8.1 11.5 9.1 12.4 12.1 19.4 12.4 9.2 8.5 12.9 12.3 20.6 27.1 10.2 14.2 13.4 21.3 12.1 12.6 10.5 20.7 19.6 36.3 16.3 13.9 13.5 18.7 12.7 12.7 12.7 10.8 18.5 23.4 15.6 13.7 21.7 18.9 19.1 20.6 3.0 20.6 14.1 17.9 20.1 10.7 18.1 19.2 20.1 20.2 17.5 21.8 20.0 11.8 23.0 13.0 0.0 11.5 24.3 38.6 28.2 12.5 17.8 17.8 21.4 11.4 15.7 9.8 45.1 48.0 20.2 14.8 15.7 12.9 0.0 14.0 44.2 34.2 17.7 25.4 15.7 41.6 3.2 9.1 16.0 41.1 2.7 33.9 45.8 27.0 23.4 25.0 17.1 18.9 24.6 26.5 45.3 10.5 19.4 29.4 36.5 22.3 40.5 25.7 32.6 29.2 23.7 PPIL4 ENSG00000131013 "Peptidylprolyl isomerase like 4" Q8WUA2 6 149504733-149546038 "Enzymes, Predicted intracellular proteins" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031599, HPA031600" Approved Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA031599: AB_2673950, HPA031600: AB_10600928" "unprognostic (6.12e-2)" "unprognostic (4.90e-2)" "unprognostic (3.85e-2)" "unprognostic (8.42e-2)" "unprognostic (7.53e-2)" "unprognostic (6.36e-3)" "unprognostic (2.91e-3)" "unprognostic (2.22e-1)" "unprognostic (4.22e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (4.62e-2)" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (8.50e-2)" "unprognostic (7.94e-2)" 20.0 20.1 20.6 15.0 35.5 30.6 21.2 35.1 27.8 24.0 15.3 19.7 10.1 14.1 21.1 27.2 15.7 18.0 19.8 18.3 21.3 15.6 18.8 23.0 17.9 15.7 20.9 18.0 32.9 16.0 20.8 36.6 22.6 23.9 20.5 16.8 15.7 18.2 16.7 14.8 15.4 16.0 20.0 22.7 17.6 16.0 15.9 19.4 27.0 26.8 8.2 16.8 22.0 19.2 21.4 16.6 24.9 17.8 28.7 24.6 14.8 11.1 6.0 21.0 17.3 12.5 16.4 19.6 22.0 21.0 24.1 25.7 12.6 11.4 11.8 15.2 16.9 14.4 10.1 16.0 8.4 38.3 17.1 15.1 13.0 13.2 21.6 19.7 23.6 11.1 12.8 14.4 24.6 20.6 13.5 13.1 8.6 28.3 7.1 18.7 11.9 13.4 20.3 16.6 11.2 9.5 18.2 19.4 5.9 18.3 8.5 12.4 9.5 26.2 11.5 15.0 15.2 13.5 17.2 15.3 16.0 12.5 28.3 20.9 9.4 4.8 18.5 13.5 19.0 23.0 24.9 16.1 18.1 14.7 17.8 20.4 21.4 19.5 16.9 16.6 16.6 24.6 18.7 13.4 28.7 16.1 16.2 20.7 14.8 20.6 35.5 35.1 27.8 21.3 15.6 20.9 18.0 23.9 19.4 62.5 64.3 22.6 54.3 43.4 44.2 33.3 17.8 80.3 61.4 43.6 7.9 43.1 36.5 34.7 17.2 37.3 15.2 0.0 23.1 37.9 55.5 27.1 73.0 18.7 31.8 27.0 22.3 30.7 21.3 9.6 57.2 29.9 38.8 47.7 19.7 40.0 26.4 22.9 52.6 27.5 35.5 51.8 68.4 58.2 53.4 39.5 54.6 41.5 20.0 32.7 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.5" "Group enriched" "Detected in many" 4 "Ciliated cells: 187.4;Early spermatids: 262.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 6.5;ASC diff: 10.4;ASC TERT1: 12.9;hTERT-RPE1: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.5 1.4 5.5 1.1 8.6 0.7 3.6 5.0 4.8 4.6 1.7 7.2 7.4 1.9 3.8 12.7 2.0 36.5 1.7 2.6 6.0 5.4 4.9 1.2 8.9 1.1 3.4 3.2 6.3 4.3 6.6 7.6 1.6 18.3 1.8 1.6 2.6 2.8 5.0 3.9 1.7 1.1 5.4 3.2 1.3 2.3 20.4 5.3 0.0 17.2 1.4 1.1 2.9 2.0 5.1 1.7 2.0 1.3 1.7 1.3 1.1 1.8 1.0 1.2 6.5 10.4 12.9 1.1 0.0 2.3 0.5 0.2 0.1 1.8 0.0 0.5 0.6 0.9 1.2 1.0 0.0 0.3 0.5 0.9 0.5 0.1 0.0 5.2 0.6 0.3 2.7 6.2 0.2 3.9 9.3 0.8 1.4 0.9 0.3 0.4 0.6 0.1 0.6 0.2 4.2 1.3 0.8 0.0 0.6 5.0 0.1 1.5 2.5 0.2 0.3 4.3 0.3 0.5 1.0 0.4 0.1 0.2 1.1 0.2 0.3 0.1 0.1 2.1 0.1 0.4 2.0 1.2 1.2 0.9 1.3 0.9 5.1 1.2 1.1 1.7 3.2 1.1 1.0 1.6 1.7 1.1 1.7 1.3 1.1 5.5 8.6 5.0 4.8 6.0 5.4 3.4 3.2 18.3 5.3 6.0 5.8 0.0 3.5 1.9 2.1 3.3 5.1 187.4 22.7 3.5 2.0 0.5 21.6 1.6 262.5 1.5 0.7 0.0 1.0 0.7 1.7 2.9 0.0 0.0 0.3 1.6 2.9 0.6 0.0 40.8 4.9 0.5 3.3 1.0 1.8 4.9 0.7 0.0 4.9 8.0 11.5 0.0 1.2 52.6 22.0 2.6 0.6 0.5 1.7 1.1 PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Early spermatids: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" NA NA "Nuclear bodies" "HPA019353: AB_1855668, HPA019360: AB_1855669" "unprognostic (3.31e-2)" "unprognostic (2.07e-2)" "unprognostic (6.78e-2)" "unprognostic (2.85e-1)" "unprognostic (9.61e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.37e-1)" "unprognostic (4.97e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-3)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.72e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" 17.5 15.8 24.3 23.5 26.1 26.0 18.9 28.3 29.7 21.3 16.5 17.9 16.8 15.0 22.0 20.9 17.3 20.4 17.1 14.9 20.0 12.6 14.2 17.3 16.3 28.7 20.9 18.3 26.0 18.6 22.7 26.9 20.9 20.9 18.7 21.5 13.1 16.6 17.7 18.0 23.7 21.2 16.9 19.3 28.9 17.8 19.1 21.1 32.4 19.5 15.2 26.7 16.7 23.7 15.6 13.5 18.1 12.3 15.4 23.3 14.5 19.5 12.9 19.4 18.8 17.1 21.2 20.7 19.0 13.6 20.5 25.7 19.5 19.4 22.2 15.1 13.6 26.9 17.4 21.0 19.5 27.9 18.5 18.3 13.7 20.3 17.1 14.9 12.7 14.5 16.8 8.0 19.7 14.0 14.2 17.6 17.0 18.7 15.6 16.2 19.7 19.6 16.1 13.6 7.6 7.7 18.3 25.9 18.7 12.0 16.5 9.9 7.9 18.7 8.1 16.9 15.7 11.9 16.8 13.4 11.3 15.8 12.1 27.8 8.9 13.3 23.2 12.4 18.8 12.0 18.1 10.1 16.7 17.2 11.1 20.7 15.6 18.9 18.7 13.5 12.3 23.3 20.4 8.2 15.4 12.3 7.8 20.7 14.5 24.3 26.1 28.3 29.7 20.0 12.6 20.9 18.3 20.9 21.1 26.8 15.3 15.7 13.4 11.0 15.8 15.9 2.5 20.1 27.3 10.4 7.9 23.5 8.3 7.4 68.1 14.3 6.6 23.3 6.6 11.2 13.4 6.0 10.5 4.2 10.2 6.4 9.2 16.5 14.2 27.5 18.7 10.8 13.5 19.0 14.2 14.9 7.6 14.0 17.7 6.5 20.4 6.5 11.0 20.2 31.1 10.3 21.1 20.0 10.3 7.2 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 286.6;retina: 331.2" "Group enriched" "Detected in many" 11 "Leydig cells: 35232.9;Peritubular cells: 61248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 27 "plasmacytoid DC: 140.9" "Lineage enriched" "Detected in many" 27 "dendritic cells: 140.9" "Group enriched" "Detected in some" 6 "HHSteC: 106.3;HSkMC: 51.8" "HPA004938, CAB009916" Approved "Secreted to blood" NA NA 4300000000 "CAB009916: AB_2174617, HPA004938: AB_1855745" "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 34.1 27.9 138.1 37.5 159.8 2.5 11.3 61.5 154.6 260.4 10.5 192.5 23.0 6.4 22.5 130.0 26.0 72.4 65.8 286.6 121.0 85.2 22.3 6.0 39.7 114.8 170.8 130.6 7.0 20.0 1.8 20.6 38.5 118.8 78.5 4.2 331.2 18.8 149.8 17.0 19.7 11.2 18.6 188.0 50.1 13.5 218.5 103.2 3.3 3.4 4.3 51.1 49.5 75.8 0.0 140.9 0.2 0.1 0.3 5.2 1.0 0.0 0.0 0.0 0.0 1.0 3.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 4.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 106.3 0.0 0.2 51.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.2 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.1 13.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 5.2 0.1 0.3 0.0 0.4 0.6 0.1 0.0 0.1 1.1 0.2 0.3 0.0 140.9 0.1 1.0 138.1 159.8 61.5 154.6 121.0 85.2 170.8 130.6 118.8 103.2 0.0 1.1 0.0 3.5 62.5 41.8 283.2 0.0 0.0 0.0 130.9 49.1 12.3 58.0 0.3 163.9 98.7 0.0 0.0 0.0 31.2 935.4 19.2 1.1 1.6 48.0 20.6 0.0 51.5 2.8 458.6 35232.9 41.1 199.1 1.8 0.0 4317.3 1.2 0.0 61248.9 0.6 110.6 161.7 44.3 116.5 105.1 70.0 29.6 37.4 0.0 14.4 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753047 "Enzymes, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ductus deferens: 59.8;placenta: 51.7;seminal vesicle: 182.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 118.4;Extravillous trophoblasts: 226.1;Fibroblasts: 92.9;Syncytiotrophoblasts: 231.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "basophil: 16.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 16.8" "Cell line enhanced" "Detected in many" "ASC diff: 30.0;BEWO: 31.9;GAMG: 57.8;HaCaT: 41.7;SK-BR-3: 30.6;U-2197: 79.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 17.0 0.6 1.1 6.2 1.7 3.0 16.7 1.1 1.8 11.9 4.2 0.8 59.8 1.2 2.0 9.1 8.7 2.7 4.1 4.2 2.1 3.5 3.9 0.4 3.5 3.1 1.3 0.7 2.7 0.6 6.3 0.7 51.7 2.1 11.2 2.0 2.9 16.3 182.9 2.5 19.8 3.7 4.8 1.4 1.3 3.4 9.9 0.6 2.3 1.7 6.6 14.1 14.5 15.0 0.0 0.1 16.8 3.2 0.0 0.0 0.1 0.2 18.7 0.0 8.9 30.0 10.4 31.9 1.4 12.3 0.2 0.3 0.9 13.7 0.0 0.5 3.4 57.8 41.7 0.1 1.4 0.1 0.0 0.1 0.0 13.3 0.0 0.7 0.0 0.0 6.1 9.7 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 8.9 1.6 0.0 0.0 0.0 1.0 19.9 0.1 0.7 16.7 30.6 0.1 1.3 16.0 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.0 15.7 0.0 0.1 16.8 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 3.2 0.0 0.0 0.1 1.1 1.7 1.1 1.8 2.1 3.5 1.3 0.7 2.1 0.6 0.0 0.0 0.0 8.2 15.9 0.0 0.0 0.0 0.0 4.5 3.5 0.0 118.4 1.7 10.6 0.4 0.3 0.0 0.0 1.0 226.1 92.9 6.9 1.1 0.0 15.4 0.0 7.0 0.0 0.0 0.0 0.3 3.8 13.5 12.6 6.4 0.0 5.7 0.0 0.0 0.5 0.0 0.0 11.2 0.3 0.0 37.6 231.0 0.0 0.3 38.2 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.5" "Cell type enhanced" "Detected in many" 13 "Cardiomyocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria No No Mitochondria "HPA020631: AB_1855887, HPA020733: AB_2670508" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 9.3 17.0 16.5 9.2 17.8 4.4 7.4 15.3 24.1 7.1 14.8 9.9 7.6 17.7 8.1 9.0 12.6 8.4 10.0 36.4 17.4 14.0 13.2 13.0 5.8 10.2 14.2 11.6 9.2 18.3 11.7 14.3 10.7 10.5 8.0 7.0 13.2 16.2 12.0 73.5 9.3 13.2 5.9 7.0 9.5 14.3 5.8 9.8 9.3 10.5 16.2 13.3 8.5 7.3 5.2 8.2 1.2 6.3 3.7 6.5 2.9 12.7 35.8 4.0 14.8 3.6 3.7 12.2 9.8 5.5 12.4 6.6 26.7 20.0 11.3 15.7 3.9 9.7 33.2 5.8 12.1 1.7 8.1 15.6 5.8 27.1 24.9 11.1 11.7 11.6 5.0 8.8 10.0 6.9 3.8 8.5 12.0 12.8 7.0 4.1 39.5 14.0 22.4 12.8 15.4 29.0 10.6 7.9 28.8 8.4 9.6 20.0 12.0 14.2 22.6 9.5 2.0 20.2 6.3 11.1 12.8 15.8 17.2 17.8 16.2 7.9 11.0 9.7 9.1 11.8 1.2 6.0 1.0 5.6 6.3 6.5 5.2 3.7 5.9 6.7 4.5 4.3 5.1 1.1 3.7 2.8 8.2 4.2 2.9 16.5 17.8 15.3 24.1 17.4 14.0 14.2 11.6 10.5 9.8 14.9 5.4 25.3 29.8 20.4 34.7 606.9 35.7 0.0 6.8 22.7 19.6 69.1 124.3 64.1 1.9 21.1 88.3 0.0 44.8 49.4 20.3 34.0 14.9 33.3 50.6 35.0 43.4 15.4 22.9 3.2 28.4 33.8 54.0 154.1 52.3 18.2 52.2 51.8 20.5 79.0 38.1 19.4 28.3 2.3 56.6 21.5 55.7 21.7 83.1 40.8 PTGES3 "cPGES, p23, TEBP" ENSG00000110958 "Prostaglandin E synthase 3" Q15185 12 56663341-56688408 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 358.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034319, HPA038672, HPA038673" Enhanced Approved Nucleoplasm,Cytosol NA NA 580000 Cytosol Nucleoplasm "CAB034319: AB_2175206, HPA038672: AB_10697395, HPA038673: AB_10670786" "prognostic unfavorable (2.15e-5)" "unprognostic (2.60e-1)" "unprognostic (8.67e-3)" "unprognostic (7.07e-2)" "unprognostic (2.24e-1)" "unprognostic (2.96e-3)" "prognostic unfavorable (4.44e-6)" "unprognostic (4.33e-3)" "unprognostic (3.64e-2)" "prognostic favorable (4.36e-4)" "unprognostic (2.73e-2)" "unprognostic (2.31e-2)" "unprognostic (3.05e-3)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (2.07e-1)" 44.7 41.4 56.0 41.2 55.7 39.6 175.0 44.2 51.7 49.0 51.9 38.1 49.5 46.4 57.7 52.0 52.6 69.8 36.0 46.0 54.6 57.2 52.1 67.1 46.4 62.0 67.0 41.4 82.3 55.1 43.2 49.2 50.3 57.0 60.7 55.3 24.0 36.6 49.4 64.2 37.0 46.7 64.7 72.5 42.7 36.6 39.7 65.1 53.5 72.5 36.7 55.1 72.7 358.9 40.6 36.9 27.3 74.8 29.2 42.5 60.5 81.4 71.0 57.7 34.3 42.5 38.6 87.9 53.4 40.8 68.8 51.4 60.1 85.9 90.3 81.1 45.5 46.3 52.5 108.0 69.7 87.2 66.3 71.9 70.5 44.9 69.5 31.1 83.7 51.2 27.9 51.0 51.9 63.1 65.5 70.7 58.1 113.0 86.5 67.1 50.8 83.1 79.6 98.5 71.9 83.0 72.7 54.4 121.2 60.5 63.8 74.8 43.7 54.5 78.6 46.2 79.6 90.5 70.3 42.3 41.3 48.1 49.5 73.7 36.5 100.4 72.6 45.0 69.1 74.3 27.3 37.5 23.2 32.0 59.0 42.0 40.6 42.5 38.1 36.9 28.5 42.3 36.4 14.8 29.2 74.8 31.3 42.5 60.5 56.0 55.7 44.2 51.7 54.6 57.2 67.0 41.4 57.0 65.1 166.7 121.6 178.4 623.1 343.3 128.5 151.7 150.3 313.2 146.7 179.7 72.6 370.5 316.7 252.0 38.5 189.7 176.9 116.8 186.9 545.4 268.2 456.4 232.8 165.2 311.0 106.5 250.8 168.1 180.7 81.6 221.2 245.7 268.2 312.0 185.6 201.5 190.6 194.6 200.5 268.7 99.7 142.3 307.9 546.1 341.1 330.1 473.4 233.5 241.8 443.4 PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568146 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 88.2" "Group enriched" "Detected in many" 8 "Ito cells: 78.5;Leydig cells: 24.7;Peritubular cells: 98.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 17.8;ASC TERT1: 17.9;U-2197: 55.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" 18.2 2.5 0.6 8.0 1.3 0.1 28.3 0.2 1.6 23.3 14.6 0.5 6.5 1.7 36.5 21.7 13.2 32.0 36.3 23.8 0.3 0.5 3.0 3.8 7.5 1.6 0.5 0.9 51.2 1.3 0.2 0.5 1.0 1.0 27.2 3.7 3.2 3.7 4.6 7.0 3.2 4.4 88.2 1.4 0.3 8.7 16.2 0.3 0.0 6.7 5.6 1.7 64.2 36.1 1.0 0.8 2.7 0.6 0.8 0.5 0.1 0.0 0.0 0.7 0.0 17.8 17.9 0.2 0.3 2.1 0.0 0.0 0.0 0.0 0.0 7.1 5.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.3 0.0 0.2 0.0 5.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.3 0.9 55.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.6 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.1 1.0 0.4 0.5 2.7 0.8 0.3 0.8 0.2 0.1 0.6 1.3 0.2 1.6 0.3 0.5 0.5 0.9 1.0 0.3 3.0 2.4 0.0 0.6 3.3 0.8 3.4 0.0 4.0 3.4 3.5 0.0 0.3 0.0 0.4 1.7 3.8 0.0 0.0 0.0 0.1 8.3 0.3 0.0 0.6 0.3 0.0 0.0 78.5 1.5 2.2 24.7 0.7 1.7 0.0 0.0 0.3 0.7 0.0 98.6 0.0 4.6 0.0 2.5 0.7 1.1 4.3 0.2 0.5 0.0 0.6 PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Collecting duct cells: 50.6;Cytotrophoblasts: 42.8;Distal tubular cells: 46.4;Ductal cells: 58.5;Exocrine glandular cells: 54.1;Hofbauer cells: 45.3;Pancreatic endocrine cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999" Approved Enhanced Nucleoplasm,Cytosol NA NA 4800000 Nucleoplasm Cytosol "CAB022068: , CAB035999: , HPA005695: AB_1855658" "unprognostic (4.97e-2)" "unprognostic (1.70e-2)" "unprognostic (1.13e-2)" "prognostic favorable (6.50e-5)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.65e-2)" "unprognostic (6.44e-3)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" 16.5 35.1 41.6 19.8 41.2 18.1 23.9 32.0 74.2 27.5 27.4 27.2 30.1 18.3 26.7 26.0 31.8 30.1 28.7 42.1 38.0 32.4 32.6 41.0 22.1 19.8 30.8 35.5 23.2 22.4 55.0 22.5 21.4 37.0 33.4 21.7 20.8 36.0 41.5 110.7 27.2 18.8 35.3 21.9 24.4 23.8 62.4 17.6 23.7 27.2 37.0 21.3 22.1 23.9 12.6 19.2 7.8 15.5 17.7 18.4 14.9 24.3 43.2 26.6 49.3 18.0 22.1 26.6 25.5 28.9 35.0 24.5 23.1 30.1 25.4 19.3 43.2 39.8 39.7 27.8 31.4 30.2 45.0 15.2 15.7 45.7 21.9 53.6 27.0 34.1 26.5 31.0 25.6 24.4 53.1 35.6 26.6 23.2 28.2 29.4 63.2 24.6 16.7 41.9 66.2 43.0 24.6 24.6 46.6 36.7 30.6 28.9 20.4 51.6 53.3 31.9 26.4 56.5 11.8 26.1 29.1 26.3 30.0 35.9 25.8 65.9 22.9 35.8 17.7 40.1 5.8 15.5 7.8 18.4 15.5 17.6 9.6 14.0 16.4 19.2 12.6 13.1 13.1 5.4 17.7 14.4 13.8 14.0 14.9 41.6 41.2 32.0 74.2 38.0 32.4 30.8 35.5 37.0 17.6 3.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 50.6 0.0 42.8 46.4 58.5 0.0 0.0 0.0 0.0 54.1 37.3 0.0 0.0 8.1 0.0 45.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 37.9 0.0 0.0 49.9 0.0 0.0 32.9 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 PUS1 ENSG00000177192 "Pseudouridylate synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA051636: AB_2681560, HPA057593: AB_2683479" "unprognostic (2.72e-1)" "unprognostic (9.13e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-2)" "unprognostic (8.12e-3)" "unprognostic (8.07e-2)" "unprognostic (4.57e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (3.49e-8)" "unprognostic (1.80e-3)" "unprognostic (8.06e-2)" "unprognostic (8.59e-2)" "unprognostic (1.56e-2)" 12.7 15.8 18.8 19.5 23.3 26.2 11.2 8.8 16.9 8.7 11.9 9.4 11.0 12.4 13.6 18.7 16.5 12.9 25.1 8.6 15.6 8.3 10.7 22.8 11.0 21.4 11.7 15.8 10.1 19.8 7.2 9.5 8.3 11.7 11.7 10.5 7.6 11.4 15.7 13.5 15.4 13.9 9.7 6.2 17.4 13.6 11.9 16.4 11.6 10.3 11.6 15.8 10.8 12.8 5.9 4.6 1.9 2.0 9.1 4.0 1.3 15.4 20.2 4.8 8.5 4.6 7.9 29.5 11.9 5.0 9.1 5.9 22.3 10.1 18.4 13.8 6.5 7.1 19.6 15.8 11.3 5.9 8.1 31.9 18.5 9.8 19.4 12.5 31.7 17.1 8.0 9.2 10.4 8.9 4.4 8.9 12.9 22.9 5.7 5.2 26.8 20.8 28.5 25.3 12.6 30.8 19.9 6.8 19.1 7.4 21.5 13.4 7.5 10.0 13.7 11.0 4.9 15.0 34.3 7.7 7.3 15.6 15.4 17.2 15.6 11.7 21.9 7.5 25.4 10.0 1.2 2.0 0.4 3.2 1.4 2.2 5.9 2.7 3.3 1.6 5.5 4.0 2.1 1.9 9.1 1.3 4.6 2.4 1.3 18.8 23.3 8.8 16.9 15.6 8.3 11.7 15.8 11.7 16.4 0.0 6.7 10.0 16.1 26.3 5.2 4.5 12.7 4.0 3.4 5.2 21.6 12.0 5.0 9.3 0.6 9.0 4.5 0.0 8.2 14.4 9.6 13.4 16.1 11.3 13.6 0.0 13.8 8.0 7.3 2.0 7.2 8.9 6.8 8.2 17.2 4.6 12.7 7.0 8.9 10.4 9.6 6.5 11.8 16.5 22.1 19.8 7.2 7.5 15.5 13.7 PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridylate synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: AB_2679066, HPA049582: AB_2680824" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-2)" "unprognostic (2.90e-2)" "unprognostic (8.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-4)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" "unprognostic (9.45e-2)" "unprognostic (1.15e-3)" 7.0 8.7 7.4 5.0 7.3 3.9 7.3 6.8 7.9 4.8 10.0 5.1 3.0 9.2 7.7 9.1 5.0 5.4 6.4 4.6 6.5 6.9 8.5 17.6 6.3 6.5 8.5 4.6 6.8 7.2 6.3 10.3 4.2 5.9 6.6 6.0 6.7 6.2 3.9 6.7 4.3 19.8 3.6 7.1 5.9 4.2 7.8 8.0 9.1 10.4 4.1 8.3 4.4 4.4 5.2 4.9 9.8 6.9 4.8 4.3 1.8 2.7 1.6 4.5 7.7 4.0 4.4 5.2 5.7 5.3 5.6 5.3 4.3 3.9 8.7 5.9 3.2 5.2 3.0 5.1 4.6 6.8 8.8 2.5 7.9 2.1 13.4 7.1 8.7 5.0 5.2 5.4 3.9 9.5 6.9 7.0 8.7 8.1 6.1 3.8 2.5 6.9 7.0 4.1 2.1 3.0 6.8 6.0 4.4 3.2 5.3 2.6 3.6 4.5 8.0 9.1 3.2 3.1 5.6 5.3 5.4 4.2 3.5 4.1 7.4 3.2 18.6 4.6 5.2 6.0 9.8 1.9 2.0 3.9 2.2 4.3 5.2 2.5 2.6 1.6 3.2 3.0 3.4 4.1 4.8 6.9 4.9 1.5 1.8 7.4 7.3 6.8 7.9 6.5 6.9 8.5 4.6 5.9 8.0 0.0 11.0 1.9 2.2 2.2 6.8 4.2 0.0 10.7 3.4 3.5 0.0 5.2 6.6 2.6 1.5 3.9 16.5 0.0 4.4 3.8 2.8 2.9 0.0 11.6 5.3 1.6 1.2 6.2 5.1 1.1 2.8 3.2 1.7 10.8 2.0 6.5 4.3 2.9 1.4 5.1 6.3 6.5 2.1 7.1 10.9 1.9 10.4 5.7 3.3 4.3 PUS3 FKSG32 ENSG00000110060 "Pseudouridylate synthase 3" Q9BZE2 11 125893485-125903221 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038040, HPA063802" Uncertain Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA038040: AB_10697092, HPA063802: AB_2685126" "unprognostic (5.89e-2)" "unprognostic (7.24e-2)" "unprognostic (1.29e-1)" "unprognostic (4.37e-3)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (7.67e-2)" "unprognostic (1.77e-1)" "unprognostic (8.92e-3)" "unprognostic (4.47e-3)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-3)" "unprognostic (9.95e-2)" "unprognostic (1.32e-1)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" 8.6 8.8 5.9 7.4 7.7 2.3 8.7 9.0 8.4 7.4 9.2 3.6 4.6 9.9 8.4 8.6 8.1 6.4 5.9 7.6 8.0 6.4 9.6 36.6 6.1 11.0 8.7 7.2 7.7 17.9 8.2 21.1 7.6 7.7 10.4 7.4 5.4 10.6 5.1 15.2 8.2 11.5 13.9 9.7 8.9 9.3 5.3 7.3 9.6 12.4 10.6 9.2 11.1 7.3 13.0 8.8 9.9 12.3 13.0 16.5 7.1 3.5 4.3 13.2 14.7 13.5 17.2 6.3 11.7 9.8 6.7 7.5 13.9 13.3 17.9 19.4 5.2 9.8 12.2 21.3 10.9 6.8 15.2 10.3 18.4 5.4 10.0 14.3 11.5 5.4 13.6 13.1 8.0 17.1 9.9 12.3 13.5 18.7 9.3 7.2 2.1 12.8 12.3 11.4 26.3 8.4 2.5 12.0 10.1 11.0 5.6 15.3 13.6 8.0 11.2 6.4 9.9 24.0 7.5 8.3 14.2 5.8 6.7 9.6 7.0 10.5 18.8 3.8 18.6 9.7 9.9 9.7 7.8 13.0 9.4 15.2 13.0 12.8 12.5 8.8 12.2 16.5 15.6 3.7 13.0 12.3 7.8 12.9 7.1 5.9 7.7 9.0 8.4 8.0 6.4 8.7 7.2 7.7 7.3 8.9 8.6 9.0 9.4 11.4 9.1 5.2 15.3 8.1 14.8 5.2 27.5 7.4 5.0 12.3 5.9 7.7 4.2 23.3 23.5 10.6 5.6 7.1 12.7 28.8 7.2 4.8 4.6 7.4 3.2 4.3 7.2 5.4 1.7 3.6 3.9 8.9 13.5 3.5 7.4 14.6 10.4 6.5 11.0 4.6 6.9 10.3 11.7 7.5 6.0 9.3 RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935263-153944691 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 32.7;lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" 10 "granulocytes: 128.8;Hofbauer cells: 156.0;Ito cells: 72.4;Proximal tubular cells: 157.3" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 13.2;HMC-1: 44.8;SK-MEL-30: 29.7;U-266/84: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA000428, HPA000522" Enhanced NA NA 42000 "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" 12.7 11.1 7.8 11.2 16.8 8.6 8.4 2.3 11.5 4.2 6.2 11.3 1.1 7.4 2.1 6.0 3.0 2.5 5.7 8.7 9.4 9.1 32.7 4.6 12.8 12.1 16.9 7.4 1.2 1.6 1.8 3.4 8.1 11.6 3.6 3.0 9.6 3.4 2.0 1.4 5.2 7.5 4.5 12.7 36.5 4.4 1.4 13.5 3.0 2.9 1.1 4.4 5.7 2.9 1.1 0.6 5.3 3.1 0.3 0.9 0.7 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 10.0 0.0 0.9 7.7 0.0 44.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 2.8 3.5 0.0 0.2 2.0 0.1 0.1 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 29.7 1.1 0.0 3.5 0.4 0.0 0.3 0.0 0.0 4.5 25.7 1.8 0.9 4.7 3.5 2.9 2.0 5.3 0.3 1.4 0.3 1.1 0.1 0.1 0.2 0.6 0.9 0.4 4.5 0.3 3.1 0.6 0.0 0.7 7.8 16.8 2.3 11.5 9.4 9.1 16.9 7.4 11.6 13.5 0.0 2.1 9.7 1.1 4.1 1.6 0.8 5.1 0.0 0.0 8.7 0.0 1.0 31.5 1.0 0.0 4.3 1.3 0.0 0.3 4.4 2.3 1.3 128.8 0.8 156.0 14.3 1.7 72.4 62.0 0.0 0.3 37.4 27.0 35.1 0.5 12.6 0.5 0.9 0.4 157.3 0.7 12.9 3.9 0.0 1.2 1.8 2.4 7.9 0.5 0.4 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022259 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (5.07e-2)" "unprognostic (8.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.42e-6)" "unprognostic (1.59e-3)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "unprognostic (5.84e-2)" 19.4 26.9 20.6 16.7 28.0 14.6 22.6 26.4 27.7 18.7 19.7 23.3 20.7 17.4 27.8 21.5 24.0 17.6 17.3 17.2 21.1 21.0 26.7 23.3 19.4 21.6 21.7 21.7 22.9 14.1 14.8 41.9 24.4 18.6 20.5 26.6 18.9 18.3 27.9 12.3 17.2 16.0 27.1 25.8 15.6 19.8 11.9 19.7 23.5 25.2 14.5 23.2 24.1 20.2 8.6 28.9 8.0 20.5 30.5 10.7 11.3 20.6 26.8 17.4 17.5 28.3 27.4 29.9 27.2 21.8 25.9 34.8 38.5 31.7 13.9 17.9 21.0 35.1 20.3 25.6 29.0 39.6 16.7 18.1 25.8 39.3 35.9 38.6 27.3 19.9 19.2 28.9 29.7 38.7 23.6 33.7 13.9 25.9 19.4 21.2 32.9 14.8 23.8 25.5 41.7 19.6 18.7 20.8 19.9 29.9 30.9 20.9 12.0 23.0 22.5 18.2 32.8 19.4 31.4 27.6 34.8 23.2 16.9 25.1 11.7 14.8 29.9 25.2 27.0 22.5 6.9 17.3 8.0 10.2 20.5 8.9 8.6 8.0 9.6 28.9 8.4 10.7 9.6 1.7 30.5 13.7 10.6 10.7 11.3 20.6 28.0 26.4 27.7 21.1 21.0 21.7 21.7 18.6 19.7 6.0 6.9 14.7 13.5 14.7 12.5 5.3 7.6 13.4 19.4 17.4 19.6 32.4 26.6 20.5 8.8 11.9 12.3 23.3 15.1 36.8 15.5 12.1 5.8 15.5 33.1 9.5 9.8 17.2 17.6 9.3 10.3 20.4 13.5 16.2 14.2 8.2 17.4 14.0 13.8 37.0 12.9 6.5 14.1 16.4 16.1 17.8 21.4 11.4 18.9 12.0 RPEL1 ENSG00000235376 "Ribulose-5-phosphate-3-epimerase like 1" Q2QD12 10 103245887-103248016 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 1.4;brain: 1.2;pituitary gland: 1.2" "Cell type enhanced" "Detected in some" 16 "Bipolar cells: 2.9;Cone photoreceptor cells: 7.9;Rod photoreceptor cells: 2.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HeLa: 1.1;NB-4: 1.1" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (7.52e-2)" "unprognostic (1.69e-1)" "unprognostic (4.78e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.83e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.91e-2)" "unprognostic (6.59e-2)" "unprognostic (4.34e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (1.62e-1)" "unprognostic (6.72e-2)" "unprognostic (5.06e-2)" 0.0 0.1 0.1 1.0 0.3 0.1 0.1 1.2 0.2 0.0 0.0 0.3 0.4 0.4 0.1 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.4 0.1 0.0 0.8 0.0 1.2 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.4 1.0 0.3 0.7 1.4 0.6 0.2 0.5 0.5 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.4 0.7 0.1 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.3 1.1 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.1 0.7 0.2 0.0 0.0 0.1 0.3 0.5 0.2 0.3 0.1 0.3 0.4 0.2 0.1 0.1 0.4 0.0 0.1 0.9 0.1 0.2 0.3 0.1 0.3 0.7 0.4 0.1 0.3 0.7 0.2 0.5 0.7 0.5 0.4 0.4 0.3 1.0 0.4 0.5 0.6 0.0 1.4 0.4 0.3 0.4 0.2 0.0 0.0 0.0 0.1 0.1 2.9 1.5 0.0 0.0 1.2 0.0 7.9 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.2 0.3 0.3 0.0 0.7 0.0 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691644-88750935 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Cytotrophoblasts: 210.0;Syncytiotrophoblasts: 188.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 4100000 "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 12.9 8.8 6.6 15.6 7.0 43.0 12.1 11.1 6.4 8.1 12.7 6.1 11.0 12.4 11.1 7.3 18.3 8.5 14.0 10.9 5.0 4.9 6.8 6.2 9.0 16.2 7.2 3.8 11.7 26.5 3.6 11.4 26.1 6.5 8.8 13.4 6.0 12.6 8.5 17.6 9.2 12.7 7.7 5.1 15.4 10.4 8.9 7.6 30.7 9.6 10.5 19.3 8.1 11.8 18.5 14.1 21.4 12.5 13.3 22.4 11.6 8.5 5.0 10.2 8.1 7.2 7.4 22.4 4.8 4.5 7.9 5.4 17.8 11.4 43.7 10.4 5.5 10.9 5.2 12.7 4.0 12.5 20.7 16.5 17.5 3.2 17.6 7.3 32.0 12.9 6.8 3.4 7.0 11.0 3.9 11.1 23.4 18.7 7.6 7.4 13.4 35.1 28.1 9.2 28.4 8.3 18.4 12.1 10.7 6.5 13.8 7.3 8.3 5.7 7.4 11.0 5.8 4.0 13.2 6.3 4.7 12.4 15.4 13.6 5.9 4.8 43.8 4.8 29.1 6.7 5.5 9.7 21.4 11.1 9.8 14.2 18.5 15.5 16.4 14.1 15.4 22.4 18.4 2.3 13.3 12.5 6.8 12.6 11.6 6.6 7.0 11.1 6.4 5.0 4.9 7.2 3.8 6.5 7.6 11.9 10.4 45.3 15.3 33.2 8.7 11.4 15.3 2.7 3.4 19.2 2.0 210.0 8.3 13.5 6.8 26.6 15.2 70.0 30.1 69.7 29.7 21.6 21.8 5.9 38.8 12.7 18.4 17.8 15.5 2.6 18.4 22.5 38.8 25.2 24.7 4.3 21.4 28.1 17.7 12.9 5.1 19.4 18.0 25.3 32.5 35.8 188.7 37.3 56.2 35.5 SPO11 "CT35, SPATA43, TOPVIA" ENSG00000054796 "SPO11, initiator of meiotic double stranded breaks" Q9Y5K1 20 57329759-57343994 "Enzymes, Plasma proteins, Predicted intracellular proteins" Meiosis "DNA-binding, Hydrolase, Isomerase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 142 "testis: 14.2" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 58.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Daudi: 1.7;SiHa: 1.3;U-698: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.6 11.7 0.0 0.0 0.0 0.0 0.0 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 11.6 12.6 17.1 7.7 14.7 13.9 16.7 12.2 24.9 8.4 10.4 13.9 11.4 7.9 10.9 11.3 12.9 10.0 9.6 12.6 15.2 13.0 10.3 9.0 10.9 7.0 12.6 15.6 9.8 14.8 11.0 9.7 6.5 12.4 9.6 8.8 10.6 11.9 9.3 16.9 13.4 7.5 15.0 13.2 7.3 9.2 13.8 9.0 13.4 13.8 6.1 6.0 12.1 7.3 9.7 15.5 5.2 12.6 13.9 13.5 8.7 7.3 13.5 24.4 9.1 13.3 14.1 11.9 15.7 9.8 10.4 10.8 12.4 9.3 13.9 2.1 16.2 7.7 15.6 6.7 5.8 13.3 16.1 13.1 7.2 9.9 4.7 13.4 2.0 4.0 11.9 5.9 23.2 11.2 12.1 15.2 14.8 7.4 10.2 23.1 4.3 14.2 2.7 5.1 7.0 10.1 23.5 27.7 6.4 12.0 3.4 4.8 12.3 13.6 1.7 7.1 8.3 10.7 5.0 11.9 11.2 7.9 12.7 9.3 9.0 12.2 2.5 20.0 6.7 15.2 2.4 8.2 5.2 9.5 8.7 9.9 9.7 12.3 10.1 15.5 8.9 10.4 13.5 1.0 13.9 12.6 10.4 8.9 8.7 17.1 14.7 12.2 24.9 15.2 13.0 12.6 15.6 12.4 9.0 3.0 3.0 1.4 3.9 2.6 7.6 3.6 0.0 5.3 3.4 1.8 0.0 4.2 11.6 8.3 1.1 3.2 2.2 0.0 6.0 3.1 4.6 2.4 0.0 2.6 8.0 15.9 1.7 8.0 3.2 1.0 3.7 3.6 5.0 13.6 2.8 10.8 5.8 0.0 4.9 4.9 5.3 0.0 3.8 14.0 4.7 2.0 2.9 2.5 3.1 2.0 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 67.1;lymphoid tissue: 51.7" "Group enriched" "Detected in many" 5 "granulocytes: 69.3;Hofbauer cells: 78.3;Kupffer cells: 159.9;Macrophages: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "basophil: 38.1;classical monocyte: 44.5;eosinophil: 45.2;intermediate monocyte: 67.1;myeloid DC: 18.7;neutrophil: 38.8;non-classical monocyte: 56.4" "Group enriched" "Detected in all" 20 "dendritic cells: 18.7;granulocytes: 45.2;monocytes: 67.1" "Cell line enhanced" "Detected in some" "NB-4: 35.3;PC-3: 11.4;RPTEC TERT1: 10.1;U-937: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA031257, HPA031258, HPA031259" Enhanced NA NA 32000000 "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.5 7.7 6.6 17.6 8.9 13.8 5.4 1.5 5.6 3.7 6.3 13.9 0.8 6.5 3.2 4.1 3.4 5.0 13.9 3.7 7.6 5.7 6.1 8.1 20.3 43.9 12.6 2.0 2.5 3.1 1.4 3.5 9.0 9.0 5.2 8.6 4.4 8.2 2.6 1.6 1.9 9.3 7.9 19.3 51.7 7.1 2.0 12.7 7.5 2.4 2.2 6.1 9.3 2.5 1.3 18.7 45.2 67.1 1.5 2.2 25.1 0.1 3.0 0.1 0.0 0.6 1.9 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.4 8.3 0.0 0.0 0.8 2.8 7.4 1.0 0.0 0.0 0.4 0.5 1.1 0.0 0.2 1.0 0.3 0.0 1.0 35.3 0.1 8.3 11.4 1.3 0.0 0.5 10.1 0.0 0.1 0.5 0.1 0.0 0.3 0.0 0.0 6.7 0.9 0.3 0.1 0.7 0.5 2.4 0.4 0.1 0.2 28.7 0.9 38.1 44.5 45.2 1.1 67.1 1.7 1.3 2.2 0.6 18.7 0.5 0.3 0.2 38.8 1.5 56.4 3.3 2.0 25.1 6.6 8.9 1.5 5.6 7.6 5.7 12.6 2.0 9.0 12.7 3.0 16.2 6.0 0.9 0.3 1.0 0.8 7.6 1.4 2.3 1.8 5.9 0.4 8.3 4.3 0.4 2.9 0.1 0.0 8.4 0.6 0.8 7.4 69.3 4.0 78.3 3.2 1.7 18.4 159.9 0.4 0.3 116.3 3.3 16.2 2.0 3.2 3.9 7.0 0.0 4.6 3.8 19.4 0.9 0.4 0.4 0.5 0.5 14.9 2.7 1.0 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715298 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.8 16.8 14.7 22.8 31.3 12.2 20.5 28.0 34.2 16.4 15.4 14.0 16.0 17.8 22.1 21.7 16.9 18.3 16.8 20.2 17.1 18.2 19.2 19.9 23.3 25.6 14.2 18.7 16.0 16.3 20.4 19.3 19.6 26.8 18.7 16.9 18.2 14.6 16.3 14.1 16.5 21.1 21.1 16.7 26.3 15.2 11.1 11.1 29.6 19.2 13.4 22.1 19.9 14.8 4.9 9.6 3.4 6.9 7.6 8.7 4.1 3.4 5.5 10.7 8.3 22.1 23.7 7.9 27.2 29.1 19.8 22.2 2.6 10.2 9.8 5.4 39.5 8.4 13.0 7.0 13.6 30.5 9.3 6.3 9.0 8.7 4.5 23.5 19.0 14.9 18.8 8.8 21.4 19.4 20.3 25.1 8.6 5.7 13.7 23.5 2.1 10.2 6.0 4.5 2.8 9.0 9.5 21.2 11.9 16.8 7.5 10.3 8.0 13.2 8.6 10.0 11.1 5.6 16.3 24.0 35.5 9.7 7.9 19.8 9.2 9.2 9.2 21.5 15.8 25.9 2.6 4.3 3.4 6.1 6.9 8.7 4.9 6.3 5.6 6.9 3.6 7.1 6.9 1.1 7.6 4.7 9.6 6.4 4.1 14.7 31.3 28.0 34.2 17.1 18.2 14.2 18.7 26.8 11.1 26.8 23.8 18.0 14.7 18.0 26.7 19.3 15.3 33.5 17.0 15.7 17.7 12.5 1.7 13.7 2.1 24.0 10.8 0.0 8.8 17.9 26.7 15.3 19.7 22.1 16.4 25.4 17.2 30.1 22.9 2.3 22.5 24.0 23.6 7.2 13.0 24.1 13.2 11.9 15.6 5.7 31.8 38.8 20.6 18.2 26.0 21.2 10.4 19.3 7.6 14.0 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028818-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Syncytiotrophoblasts: 670.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" No Yes "Nucleoplasm, Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 26.6 31.0 24.6 46.3 25.3 55.3 37.4 39.6 31.1 21.3 30.0 11.1 26.7 29.7 22.9 22.5 36.0 20.5 29.2 21.0 23.0 18.3 31.8 32.7 37.9 38.6 21.9 20.9 25.5 22.5 22.2 39.9 43.9 25.2 23.3 27.2 13.6 25.3 34.3 26.2 24.6 48.4 23.1 27.4 36.9 26.7 14.2 24.2 54.2 31.5 25.1 40.6 25.2 41.7 9.0 17.2 18.4 11.1 5.8 8.2 4.6 22.0 15.4 28.9 23.7 11.7 14.0 28.7 20.0 17.6 23.2 21.2 40.5 27.8 62.9 21.4 10.3 24.8 21.5 34.7 31.9 34.1 13.6 17.7 80.2 12.4 28.7 30.6 34.5 27.6 15.8 17.0 22.6 37.2 20.8 24.2 23.0 34.7 21.9 26.2 49.0 48.8 21.9 23.3 22.1 28.8 41.7 27.2 33.4 24.8 20.5 24.1 16.7 31.3 19.4 20.3 21.8 21.6 30.9 23.7 18.8 16.0 17.4 21.4 13.9 15.6 73.3 25.3 19.4 17.8 9.1 9.2 14.3 6.5 9.2 8.2 9.0 7.2 6.8 8.6 8.7 7.7 6.9 18.4 5.8 11.1 17.2 7.9 4.6 24.6 25.3 39.6 31.1 23.0 18.3 21.9 20.9 25.2 24.2 110.2 181.3 71.6 274.4 218.4 93.3 38.9 84.1 73.6 228.6 94.2 56.9 139.0 63.0 78.8 6.3 78.8 108.1 210.2 57.1 149.4 129.3 136.7 76.2 114.3 86.4 68.3 88.0 63.8 84.7 6.5 55.3 93.8 69.2 72.1 73.8 94.4 93.7 112.2 65.4 91.4 80.4 84.1 77.1 95.2 57.3 187.2 670.2 61.2 78.0 206.2 TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MOLT-4: 58.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" 11.7 13.5 8.1 13.7 9.8 33.0 22.1 2.2 10.3 14.7 10.7 4.5 3.9 6.0 10.0 7.4 14.9 11.3 11.0 5.9 8.8 5.6 9.6 22.5 8.5 11.4 6.9 8.1 27.0 15.9 5.9 8.6 5.9 7.3 14.7 8.0 5.9 11.0 10.8 5.7 15.4 8.3 8.8 6.8 11.4 9.3 18.1 6.4 25.1 19.2 9.6 11.4 14.0 30.9 16.7 18.8 11.7 5.5 0.2 14.3 4.7 7.6 11.8 4.9 18.6 7.1 8.0 8.8 3.5 4.6 6.5 6.7 14.8 11.1 22.5 13.5 4.9 4.6 8.2 10.5 6.6 5.6 8.8 16.1 19.8 6.6 14.9 8.0 13.2 21.6 8.1 7.0 5.4 7.9 5.6 7.8 6.5 23.7 8.8 5.7 32.1 58.6 26.4 8.6 16.7 20.2 7.4 6.5 33.7 4.8 12.4 8.9 10.8 10.2 9.1 18.4 6.4 6.0 22.0 5.1 4.5 18.4 5.1 9.1 4.8 5.0 11.5 7.6 19.8 5.4 11.7 5.5 0.2 3.5 3.2 3.6 16.7 6.4 4.8 18.8 8.0 14.3 10.4 0.4 0.2 0.6 16.4 1.7 4.7 8.1 9.8 2.2 10.3 8.8 5.6 6.9 8.1 7.3 6.4 6.0 7.5 9.0 28.1 21.1 1.4 2.0 7.6 4.0 13.6 8.7 0.0 10.3 6.6 9.5 19.8 7.3 2.7 23.3 7.8 19.8 11.7 15.2 6.9 7.8 10.8 3.2 4.7 6.7 5.9 6.7 8.1 10.1 20.3 4.6 8.7 1.4 9.6 8.6 4.2 12.3 0.1 6.5 13.4 31.6 39.0 20.8 8.5 6.4 19.3 18.6 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388516-40417950 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 146.3;testis: 36.8" "Group enriched" "Detected in many" 4 "Erythroid cells: 280.4;Spermatocytes: 527.8;Spermatogonia: 241.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.7 2.0 0.4 20.0 0.5 14.6 4.1 0.4 0.5 3.0 6.9 0.5 0.5 7.0 2.0 3.4 18.2 0.7 2.4 2.3 0.6 0.5 1.4 1.9 5.5 15.4 0.6 0.4 1.2 1.1 0.0 0.4 10.7 0.6 1.2 8.0 0.6 3.2 0.3 0.6 5.9 9.2 2.6 1.8 7.3 4.5 36.8 0.3 146.3 0.9 11.8 16.7 3.2 5.7 1.3 0.3 0.3 0.3 3.2 5.7 1.1 34.3 45.6 58.1 26.6 2.9 5.9 12.9 47.1 25.4 43.4 38.5 21.4 26.3 55.4 24.0 15.9 26.0 54.7 44.6 18.8 58.3 29.5 29.8 36.6 29.2 35.6 0.2 51.2 39.0 1.3 1.5 30.5 31.1 9.4 22.8 36.1 39.5 38.0 46.8 11.9 59.3 34.4 24.1 24.9 18.2 50.4 90.2 23.0 10.4 22.0 34.3 24.7 38.0 47.5 15.0 35.3 39.8 23.6 14.9 28.6 40.4 33.0 45.2 21.8 24.6 48.3 16.1 35.3 47.7 0.3 0.0 0.0 0.6 0.0 0.0 1.3 0.9 0.9 0.3 0.4 0.2 0.1 0.3 3.2 0.3 0.0 5.7 1.1 0.4 0.5 0.4 0.5 0.6 0.5 0.6 0.4 0.6 0.3 0.0 1.3 28.7 1.4 10.4 0.0 1.1 2.5 0.0 6.8 0.0 0.0 8.4 0.0 0.9 12.5 0.7 2.1 280.4 0.0 81.4 9.7 1.2 0.0 3.9 64.5 0.0 0.0 27.6 30.0 15.2 4.4 13.1 1.7 2.8 5.9 0.0 0.2 3.6 1.8 0.0 0.0 71.1 1.4 527.8 241.9 5.4 7.4 7.7 24.2 2.6 TOP2B ENSG00000077097 "DNA topoisomerase II beta" Q02880 3 25597905-25664907 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Autism spectrum disorder, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004601, HPA024120, HPA050441" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB004601: AB_628384, HPA024120: AB_1858191, HPA050441: AB_2681127" "unprognostic (2.90e-2)" "unprognostic (5.17e-2)" "unprognostic (7.21e-3)" "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (7.86e-2)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" 19.3 18.8 23.4 23.1 29.7 26.5 21.1 48.4 33.5 24.1 22.4 21.1 18.9 17.1 29.6 25.6 21.1 20.6 20.7 22.7 22.0 19.9 20.3 18.4 17.7 28.2 21.0 28.5 26.8 17.2 43.0 21.6 22.3 26.4 24.7 20.8 17.6 21.3 22.3 31.3 20.9 19.3 24.4 23.4 24.6 20.1 11.3 22.7 60.2 28.3 20.7 27.3 34.8 21.5 5.5 5.6 5.3 4.6 7.8 7.2 2.2 10.7 11.1 24.6 30.1 8.2 10.4 9.8 10.4 13.4 9.7 10.6 5.7 8.5 33.3 7.3 15.0 6.0 9.1 20.3 11.6 16.3 15.9 10.9 50.4 13.8 9.5 5.8 39.4 27.0 7.4 5.8 10.8 9.5 9.8 15.7 22.8 16.9 16.4 12.4 11.9 25.5 9.7 18.6 7.2 8.5 106.6 13.8 15.4 8.7 37.9 12.4 21.5 15.5 11.1 9.5 14.8 11.5 35.3 15.0 13.5 10.5 10.7 11.1 25.4 14.4 35.3 8.8 29.5 8.9 4.2 2.9 5.3 6.3 3.3 6.9 4.3 6.1 6.4 4.3 5.5 7.2 6.4 2.0 7.8 4.6 5.6 4.4 2.2 23.4 29.7 48.4 33.5 22.0 19.9 21.0 28.5 26.4 22.7 59.6 57.9 25.1 36.1 34.8 53.5 109.0 43.3 34.8 40.9 24.4 53.0 41.2 11.6 29.3 2.9 32.2 17.7 23.3 28.8 20.8 35.0 47.5 31.4 33.5 23.1 57.2 57.0 21.5 40.9 4.8 36.2 38.8 21.9 21.6 32.6 46.4 32.0 17.5 31.5 21.9 89.3 32.3 36.7 66.2 27.0 33.0 39.0 45.0 37.9 57.7 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease mutation, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved NA NA "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 12.5 11.6 10.9 12.5 14.0 23.8 12.0 21.4 17.9 11.0 11.2 13.8 9.1 10.3 13.3 10.4 12.1 11.8 9.5 8.4 9.3 10.5 9.3 15.6 10.8 15.5 9.4 9.0 11.4 16.1 15.0 15.1 10.7 11.1 11.0 13.1 12.8 11.6 9.0 13.0 19.1 10.8 14.1 9.0 16.6 10.5 17.9 11.8 25.9 10.3 7.4 16.2 11.6 10.7 2.1 2.7 10.4 5.9 4.1 4.0 3.3 7.6 12.8 10.5 12.8 5.4 5.4 9.6 8.1 5.8 14.3 14.0 23.4 3.4 13.2 5.3 7.3 6.6 10.7 15.8 6.8 15.1 9.8 12.6 12.1 13.3 8.0 5.3 6.0 10.7 3.5 4.4 15.1 8.8 3.3 6.6 11.2 10.4 5.4 8.3 7.9 13.4 7.6 8.1 19.2 7.1 15.3 25.0 12.5 4.2 7.9 7.5 14.1 12.4 7.8 8.0 29.6 15.5 6.3 6.2 10.2 8.1 19.4 13.9 6.0 10.7 9.3 6.3 8.3 9.7 1.4 5.9 6.5 4.0 5.8 2.6 1.7 3.0 3.1 2.6 2.1 2.6 2.7 10.4 4.1 2.9 2.7 2.2 3.3 10.9 14.0 21.4 17.9 9.3 10.5 9.4 9.0 11.1 11.8 6.0 4.5 10.0 4.0 1.8 19.7 2.8 7.6 8.1 10.3 10.4 37.3 5.4 3.3 3.5 7.2 4.7 3.4 0.0 3.2 5.9 4.3 4.8 4.7 6.4 4.6 20.6 0.0 7.4 10.0 6.2 7.5 6.8 1.7 4.6 3.4 6.0 3.3 3.5 6.0 1.2 20.6 12.9 4.9 15.9 17.9 3.0 3.7 8.5 4.1 4.1 TOP3B ENSG00000100038 "DNA topoisomerase III beta" O95985 22 21957025-21982816 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072114 Approved Nucleoplasm NA NA Nucleoplasm "HPA072114: " "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (3.93e-1)" "unprognostic (2.15e-2)" "unprognostic (2.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "unprognostic (1.96e-2)" "unprognostic (1.69e-2)" "unprognostic (1.21e-1)" "unprognostic (3.53e-2)" "unprognostic (1.11e-4)" 10.4 11.7 12.1 16.1 17.4 20.8 10.9 17.2 17.1 12.5 11.0 16.9 14.9 15.4 16.1 11.0 14.2 11.0 11.2 10.1 12.7 5.5 13.4 15.3 12.7 17.0 18.7 6.5 20.2 12.1 13.5 21.0 12.1 16.2 15.6 14.9 14.1 13.3 13.3 13.4 17.5 16.1 14.5 17.4 23.6 11.8 11.1 16.9 13.1 14.2 5.7 18.9 10.5 14.3 9.0 8.8 2.7 6.8 6.1 9.3 5.2 9.7 9.3 19.1 7.6 7.1 5.9 11.9 6.5 8.1 15.0 13.3 10.1 4.2 13.4 4.9 6.7 6.3 17.9 8.6 11.5 12.1 6.8 20.6 10.5 12.0 10.4 9.6 14.3 6.9 2.9 17.6 12.4 6.0 8.7 12.5 7.8 49.2 7.3 7.0 9.9 8.9 11.1 7.8 7.1 8.9 14.1 12.7 2.1 7.4 13.0 12.5 9.1 7.9 7.1 6.0 8.0 5.5 9.2 9.0 6.2 13.0 5.8 7.9 10.8 8.8 12.7 4.8 8.7 6.4 2.5 6.7 2.7 9.3 6.8 6.5 7.5 5.8 6.5 7.4 9.0 5.9 5.7 2.3 6.1 3.8 8.8 6.7 5.2 12.1 17.4 17.2 17.1 12.7 5.5 18.7 6.5 16.2 16.9 0.0 1.6 4.7 2.3 1.5 4.5 0.0 12.7 5.3 1.2 3.5 9.8 4.1 1.7 4.1 0.9 2.5 4.1 0.0 3.7 3.0 2.8 3.6 1.1 4.4 3.5 1.6 4.6 7.4 3.7 1.1 9.8 2.7 5.0 2.8 3.9 2.4 5.2 3.5 7.1 2.2 5.3 6.5 1.4 5.4 4.7 1.4 3.3 5.7 5.6 2.5 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 234.8;skeletal muscle: 211.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles NA NA 270000000 Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 20.2 41.2 41.2 24.3 46.9 27.4 83.4 93.2 196.1 27.1 39.1 12.8 18.6 40.1 17.2 22.6 51.0 22.1 33.3 94.9 36.7 33.1 43.1 40.8 48.8 140.2 34.0 34.6 19.9 87.0 32.1 16.8 27.1 70.7 19.0 43.5 21.1 26.0 28.7 211.0 25.8 37.8 29.4 20.8 20.1 21.6 15.7 19.4 14.2 20.2 38.4 38.0 23.0 28.0 55.4 170.3 145.5 148.2 81.2 67.1 234.8 115.0 103.1 54.7 84.5 53.6 56.6 96.6 83.3 92.0 157.5 191.0 106.5 63.3 67.6 16.8 82.2 81.5 57.3 130.0 139.2 174.7 89.1 96.8 87.5 75.6 70.2 39.9 99.6 71.9 61.4 58.1 121.4 104.7 221.1 95.7 34.4 45.2 26.0 120.8 84.7 52.3 84.2 134.8 98.1 65.8 30.7 90.0 69.3 98.6 82.2 38.9 64.8 72.7 75.6 40.3 119.8 17.3 74.9 59.1 84.5 72.3 54.6 122.1 50.8 20.8 100.9 169.5 62.0 60.6 87.7 146.1 145.5 56.1 148.2 57.0 55.4 56.5 54.5 170.3 44.3 39.9 49.3 61.1 81.2 127.8 30.7 67.1 234.8 41.2 46.9 93.2 196.1 36.7 33.1 34.0 34.6 70.7 19.4 125.0 186.6 268.1 429.8 608.3 247.2 505.0 410.2 145.9 159.3 369.9 104.1 935.0 1278.3 1116.4 147.7 369.6 973.7 70.0 686.0 1611.5 538.5 310.9 357.6 425.4 827.4 281.3 408.6 284.8 382.5 523.4 258.3 552.8 639.4 1545.5 419.4 603.3 953.1 852.2 247.5 1236.2 208.3 194.1 473.8 15.1 66.8 538.4 1279.9 363.9 717.3 571.4