Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814037-151828488 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 66.2;intestine: 81.7;liver: 123.1" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 610.4" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Region enriched" "Detected in single" 7 "basal ganglia: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 11.9;ASC diff: 4.5;EFO-21: 6.4;HBEC3-KT: 5.7" "Not detected" "Not detected" HPA002911 Approved NA NA "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.58e-6)" "prognostic unfavorable (5.02e-4)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" 3.9 66.2 0.1 0.1 1.6 0.0 2.1 0.1 0.1 0.1 26.1 0.5 0.4 29.6 0.1 0.3 0.3 0.2 4.3 0.2 0.1 0.0 0.1 123.1 1.7 0.1 0.1 0.1 0.1 22.7 0.0 0.1 1.7 0.2 0.3 0.0 0.1 0.3 0.1 0.2 1.7 81.7 0.1 0.1 0.1 7.3 0.3 0.1 0.1 0.2 4.8 1.3 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 4.5 0.2 0.3 0.0 0.0 0.1 0.0 1.1 0.1 0.2 6.4 0.0 0.1 0.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.7 0.1 0.1 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.2 1.4 0.3 0.2 0.4 2.1 0.0 2.3 0.2 1.9 0.3 0.1 0.0 0.0 0.0 0.0 2.5 0.0 2.4 1.4 0.0 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 11.0 0.0 0.0 0.2 0.0 1.1 58.6 4.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.2 0.0 0.0 610.4 0.2 0.0 0.0 3.7 10.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.2 0.0 0.0 0.1 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503633-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 57.8;intestine: 49.6" "Cell type enhanced" "Detected in many" 13 "Cholangiocytes: 104.4;Enterocytes: 174.5;Paneth cells: 77.2" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 19.2" "Group enriched" "Detected in many" 8 "NK-cells: 11.4;T-cells: 19.2" "Cell line enhanced" "Detected in some" "CACO-2: 30.1;HEK 293: 9.3;HEL: 16.7;Hep G2: 8.2;RPTEC TERT1: 11.5;SH-SY5Y: 36.8" "CAB001716, HPA002199, HPA074614" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Nucleoplasm, Plasma membrane" "Focal adhesion sites" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 57.8 9.4 3.2 11.5 1.2 3.4 5.1 10.5 5.5 22.7 3.8 2.0 14.4 9.4 3.5 2.0 3.2 9.0 1.8 9.2 6.6 19.1 15.6 3.8 2.2 9.4 5.7 2.2 1.5 1.7 1.3 3.1 11.1 2.7 10.7 7.6 1.5 2.1 1.1 1.3 49.6 5.7 9.0 2.4 1.7 1.3 8.6 0.1 2.4 1.4 2.2 2.6 5.9 1.9 0.0 0.1 0.0 11.4 19.2 1.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 9.3 16.7 1.9 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.4 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.4 3.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.8 0.0 19.2 0.4 2.0 4.7 0.0 1.9 1.2 4.8 0.1 11.4 0.0 0.0 0.0 1.5 9.4 11.5 5.1 10.5 9.2 6.6 9.4 5.7 11.1 8.6 0.0 4.8 5.9 0.1 0.7 0.6 2.8 104.4 1.4 1.2 47.1 0.0 5.0 5.0 10.2 21.6 23.1 174.5 23.3 1.6 0.1 0.5 0.1 3.5 32.6 0.4 0.0 0.0 3.7 1.2 2.5 0.9 0.8 0.0 0.0 8.9 0.0 11.4 77.2 0.0 44.0 0.9 0.0 0.8 0.5 0.4 0.5 8.2 27.3 1.7 0.1 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401697-87480435 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 93.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 235.3" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "memory B-cell: 4.9;naive B-cell: 11.4" "Lineage enriched" "Detected in many" 8 "B-cells: 11.4" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.0;WM-115: 22.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.5 4.1 0.2 4.3 0.2 0.2 0.3 0.1 1.1 0.2 0.6 0.4 0.0 0.0 0.1 0.2 0.6 0.1 0.3 4.0 0.3 0.2 0.4 93.2 0.1 4.1 0.3 0.2 0.3 0.1 0.0 0.5 0.0 0.3 0.3 0.4 0.8 0.4 0.1 2.9 0.6 1.2 1.6 0.5 5.2 0.2 0.5 0.4 0.1 0.4 4.2 3.2 0.6 0.5 11.4 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 12.0 0.0 0.6 2.2 0.5 0.2 0.5 0.0 0.2 1.6 0.1 0.0 0.0 0.0 2.8 0.2 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.1 1.4 11.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.1 1.1 0.3 0.2 0.3 0.2 0.3 0.4 0.0 0.3 23.1 0.0 0.9 0.0 9.3 0.0 0.0 0.0 1.8 0.0 0.9 0.0 0.1 0.6 0.8 0.1 0.0 0.0 0.2 1.5 0.0 0.0 235.3 0.5 36.5 0.0 5.5 5.4 0.2 0.0 0.0 10.1 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.5 0.1 0.4 0.1 0.0 0.0 0.0 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10" Q9NUJ1 3 111979010-111993363 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" No No 85000 Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 8.5 18.3 17.5 8.1 27.5 7.6 12.4 23.2 23.2 9.9 11.3 13.7 8.6 9.4 9.4 42.4 7.0 12.5 8.4 19.8 18.6 19.6 39.1 26.6 9.7 14.0 17.0 21.6 16.8 12.1 8.8 26.1 8.8 19.1 17.1 12.3 12.6 19.8 12.0 10.4 8.2 8.6 8.9 14.8 12.4 11.6 12.6 15.1 16.6 25.3 6.7 12.6 8.7 7.9 18.3 19.7 17.7 14.8 7.8 12.7 10.8 18.7 16.3 18.0 5.9 10.4 14.0 9.7 19.9 10.5 16.4 15.8 16.8 10.9 17.0 11.2 8.3 11.2 10.4 7.9 11.0 22.5 5.7 10.0 14.0 8.0 14.5 8.3 28.0 15.1 8.5 8.3 8.4 21.2 11.3 17.5 20.4 6.4 7.3 17.9 6.3 26.4 13.1 11.7 20.9 25.9 23.9 11.5 7.8 17.0 8.2 12.1 8.9 15.9 11.6 18.5 7.4 13.0 10.3 9.8 9.8 12.6 7.0 10.3 11.7 4.1 29.0 9.9 15.4 10.4 17.7 11.8 17.5 7.4 14.8 12.7 18.3 9.3 8.4 19.7 15.9 12.0 10.5 1.8 7.8 11.6 12.5 8.8 10.8 17.5 27.5 23.2 23.2 18.6 19.6 17.0 21.6 19.1 15.1 0.0 4.5 17.1 8.5 6.3 20.8 20.0 7.6 18.7 9.1 10.4 7.9 15.2 29.9 4.3 0.7 7.5 5.3 0.0 6.9 12.2 9.4 5.4 9.2 22.5 12.6 39.7 11.6 11.6 20.8 1.9 9.8 11.2 10.1 2.8 10.9 18.9 4.7 2.9 7.1 27.8 12.6 0.0 10.7 29.6 34.3 7.2 4.6 10.9 10.5 4.2 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12" Q8N2K0 20 25294743-25390983 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease mutation, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 11.3 13.4 27.4 10.0 32.1 9.8 10.4 22.3 39.8 11.1 15.6 30.8 14.1 20.7 9.1 58.9 20.4 11.3 14.0 12.2 41.5 25.9 18.9 13.1 14.0 10.3 31.5 21.0 13.8 65.6 16.0 14.4 25.6 26.9 15.6 15.2 11.5 13.8 17.4 4.0 16.2 21.1 9.9 43.3 7.8 22.1 7.6 19.0 10.2 36.8 7.9 16.0 15.7 10.9 3.9 14.6 12.6 14.2 11.1 11.5 6.0 14.9 34.2 8.8 11.1 18.1 10.8 21.8 21.5 18.0 16.9 19.5 20.0 22.9 4.7 12.2 16.9 40.3 24.3 11.2 12.8 14.4 4.9 9.0 7.6 9.4 27.7 14.4 7.3 16.2 13.5 8.4 20.8 9.9 20.6 7.7 8.8 5.5 71.7 16.0 30.9 11.0 7.7 6.8 18.5 21.7 8.5 22.7 44.7 11.4 31.1 11.3 9.5 18.1 44.7 31.8 16.4 15.1 12.5 9.6 21.4 14.5 13.0 12.4 8.4 7.8 7.5 14.9 8.7 13.7 9.8 14.2 12.6 8.0 12.2 6.4 3.1 8.8 11.5 14.6 3.9 7.5 7.4 1.8 11.1 13.1 13.1 7.9 6.0 27.4 32.1 22.3 39.8 41.5 25.9 31.5 21.0 26.9 19.0 6.0 6.2 9.7 26.7 15.8 33.4 14.0 38.2 10.7 9.1 26.2 9.8 77.6 23.2 30.2 42.1 13.8 92.3 0.0 29.7 81.1 22.7 35.8 10.3 16.1 103.4 39.7 32.6 11.6 27.2 80.7 15.0 39.8 32.1 91.0 27.6 27.0 20.7 45.6 19.4 19.5 20.6 25.8 14.6 18.2 32.5 15.9 109.4 13.8 31.4 31.0 ABHD17A "C19orf27, FAM108A1, MGC5244" ENSG00000129968 "Abhydrolase domain containing 17A" Q96GS6 19 1876810-1885547 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043270, HPA047226, HPA069225" Uncertain Approved "Nuclear speckles,Vesicles" NA NA Vesicles "Nuclear speckles" "HPA043270: AB_2678401, HPA047226: AB_2679991, HPA069225: " "unprognostic (3.77e-2)" "unprognostic (1.85e-1)" "unprognostic (3.57e-2)" "prognostic favorable (1.73e-4)" "unprognostic (3.70e-2)" "prognostic favorable (6.46e-4)" "unprognostic (1.69e-2)" "unprognostic (1.92e-2)" "unprognostic (5.09e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.76e-5)" "unprognostic (1.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (1.60e-2)" 28.1 11.9 26.6 8.9 23.9 10.0 6.8 16.4 29.4 9.0 14.1 15.3 10.3 16.5 8.8 7.0 9.9 7.1 11.7 12.9 30.9 14.4 11.9 8.2 13.0 9.1 19.0 16.7 9.4 16.6 3.8 7.7 13.4 13.2 13.9 2.1 8.4 21.0 11.2 47.4 20.7 15.8 5.2 25.5 25.7 23.3 12.1 7.9 10.9 11.4 9.6 7.1 6.3 7.3 4.5 1.5 5.9 1.5 4.7 8.5 1.0 16.7 5.8 1.7 6.6 3.1 3.8 13.2 11.3 3.5 3.1 3.1 2.7 2.9 8.2 4.6 2.4 0.7 10.5 1.1 4.4 0.1 19.0 25.0 6.1 2.2 7.4 4.5 6.0 20.8 4.1 3.5 1.7 1.2 2.0 6.5 8.3 10.4 9.3 2.2 9.4 10.9 12.0 12.8 3.2 13.1 12.8 5.8 12.3 2.2 3.4 7.8 18.0 5.9 6.4 10.7 0.4 6.6 11.1 12.4 3.7 8.7 15.2 11.0 37.4 22.4 6.9 8.5 8.1 6.1 2.5 1.5 5.9 8.5 0.9 6.2 4.5 3.9 5.5 1.5 2.4 4.1 4.4 1.7 4.7 1.0 1.5 3.5 1.0 26.6 23.9 16.4 29.4 30.9 14.4 19.0 16.7 13.2 7.9 3.0 7.2 31.2 18.9 28.6 40.6 3.0 28.1 1.4 7.9 14.0 37.3 59.5 8.3 27.9 4.8 47.9 44.2 23.3 32.7 33.7 26.8 25.1 10.3 18.7 55.3 52.4 29.3 55.9 28.5 4.0 27.9 25.8 25.3 26.2 27.8 45.9 34.1 27.9 34.3 15.9 29.8 12.9 16.4 12.3 22.9 40.1 54.9 96.5 25.1 26.6 ABHD17B "C9orf77, CGI-67, FAM108B1" ENSG00000107362 "Abhydrolase domain containing 17B" Q5VST6 9 71862452-71910931 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.2" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047862 Uncertain NA NA "HPA047862: AB_10959595" "unprognostic (7.47e-2)" "unprognostic (4.41e-2)" "unprognostic (4.03e-3)" "unprognostic (5.59e-2)" "unprognostic (5.57e-2)" "unprognostic (8.53e-3)" "unprognostic (9.44e-2)" "unprognostic (6.84e-2)" "unprognostic (5.46e-2)" "unprognostic (3.44e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-1)" "prognostic favorable (2.59e-4)" "unprognostic (4.33e-2)" "unprognostic (2.12e-1)" "unprognostic (3.06e-3)" "unprognostic (1.34e-2)" 7.7 6.6 16.5 6.9 25.0 18.0 8.2 14.4 21.6 9.0 12.0 43.3 2.3 18.1 9.5 4.6 13.5 9.6 9.1 5.8 23.6 13.8 13.4 13.6 7.5 10.8 44.0 13.6 7.6 6.4 12.7 5.8 7.8 24.3 11.0 11.2 9.0 9.4 5.1 13.6 11.2 14.9 9.4 30.4 8.9 8.9 11.1 38.2 46.2 8.8 3.6 10.7 11.8 8.8 7.2 5.7 8.1 3.8 6.6 4.9 1.7 6.3 6.1 14.0 8.1 7.3 4.5 12.3 7.0 7.6 6.1 5.2 1.8 4.0 15.4 6.5 4.7 5.1 12.6 13.6 4.6 7.1 7.9 8.1 9.0 10.3 5.9 5.1 10.6 14.6 5.6 6.5 5.5 4.9 5.5 7.9 26.0 7.3 7.0 5.2 2.9 27.4 8.4 21.2 8.0 8.7 36.8 10.7 0.1 7.0 12.8 9.3 10.8 7.4 8.0 6.0 10.5 2.6 7.7 6.3 5.9 7.7 10.9 5.6 6.9 8.1 12.2 4.7 7.6 2.9 8.1 3.8 4.1 3.1 1.4 3.0 4.2 3.8 4.3 4.8 7.2 3.2 4.5 2.9 6.6 1.3 5.7 4.9 1.7 16.5 25.0 14.4 20.8 23.6 13.8 44.0 13.6 24.3 38.2 6.0 4.6 13.2 28.4 15.1 13.8 7.0 5.1 17.4 10.3 5.2 11.8 9.1 10.0 7.3 15.6 8.2 22.1 0.0 5.0 6.9 9.6 21.5 17.3 8.2 5.1 4.8 8.5 10.4 4.7 6.0 10.6 7.0 5.0 6.4 22.8 24.7 3.9 14.2 9.9 9.9 54.4 0.0 16.1 33.6 20.2 8.5 6.1 25.4 10.6 41.0 ABHD17C FAM108C1 ENSG00000136379 "Abhydrolase domain containing 17C" Q6PCB6 15 80679684-80755621 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 88.3;Mucus-secreting cells: 89.7;Paneth cells: 62.2;Urothelial cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 40.7;RT4: 33.2;SK-MEL-30: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048890 Uncertain NA NA "HPA048890: AB_2680546" "unprognostic (3.60e-1)" "unprognostic (5.07e-2)" "unprognostic (1.58e-1)" "unprognostic (2.19e-2)" "unprognostic (7.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (2.59e-2)" "unprognostic (5.08e-3)" "unprognostic (2.87e-1)" "unprognostic (1.23e-3)" "unprognostic (5.75e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.89e-3)" 2.1 3.8 14.6 16.8 16.0 3.7 8.0 6.6 13.0 13.8 42.0 5.4 4.6 15.5 4.5 1.8 31.7 7.7 12.2 3.1 10.7 8.5 10.4 5.4 27.2 11.6 8.2 8.2 2.0 8.3 5.1 6.0 19.7 5.7 12.6 38.1 3.9 16.2 6.0 1.6 12.6 25.9 6.8 6.2 5.7 23.5 3.6 5.6 2.7 7.8 13.9 23.2 13.8 13.0 1.2 1.1 0.0 0.5 0.0 2.8 0.3 8.3 8.0 5.2 6.5 1.9 3.9 8.9 8.1 30.5 6.9 6.7 6.6 18.8 2.8 3.3 8.5 4.9 17.2 14.4 7.4 6.2 19.7 8.2 0.0 6.1 7.0 3.3 2.5 4.1 8.4 9.0 4.9 2.4 6.0 7.4 2.9 0.0 3.6 3.9 23.3 0.2 0.2 7.6 40.7 3.0 5.5 4.4 7.8 5.6 33.2 4.6 1.9 6.4 11.1 36.7 2.3 5.5 4.3 2.5 4.2 3.5 4.6 7.1 0.2 0.1 2.7 2.7 23.0 4.6 0.0 0.1 0.0 2.7 0.3 2.0 1.2 2.1 2.8 0.4 0.1 0.3 0.6 0.0 0.0 0.5 1.1 0.1 0.3 14.6 16.0 6.6 13.0 10.7 8.5 8.2 8.2 5.7 5.6 11.9 8.4 1.3 6.6 6.4 4.3 3.9 17.8 6.7 6.8 7.0 7.9 1.6 38.1 5.6 0.1 2.3 88.3 0.0 7.7 4.9 2.1 23.3 0.0 4.2 1.0 9.5 13.9 4.3 1.8 0.2 1.1 1.8 8.5 1.0 89.7 3.8 18.3 62.2 0.0 4.7 20.1 0.0 1.5 0.7 5.6 19.8 0.8 2.2 41.7 77.1 ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2" P08910 15 89087459-89202360 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 303.3;Hepatocytes: 272.0;Late spermatids: 360.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 29.0;neutrophil: 22.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 29.0" "Cell line enriched" "Detected in all" 4 "HEL: 85.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005999 Approved Approved Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA005999: AB_1078080" "unprognostic (6.60e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.34e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.18e-7)" "unprognostic (4.17e-1)" "unprognostic (3.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" 13.2 24.8 14.8 9.5 19.3 15.6 11.7 25.2 23.4 10.7 16.1 12.0 6.5 23.4 18.2 34.7 9.0 12.1 32.2 24.5 12.2 11.3 11.8 76.4 22.2 11.2 11.1 14.8 13.1 28.3 11.2 18.1 5.6 19.8 22.9 9.6 22.6 11.8 10.0 19.3 7.5 18.5 11.4 8.3 14.2 35.8 42.9 7.6 7.7 8.6 8.1 12.1 13.5 10.4 1.1 3.0 29.0 7.0 4.7 3.5 2.5 8.1 15.8 3.9 4.2 7.7 10.4 2.1 5.5 16.5 5.3 5.0 3.9 14.2 2.3 6.4 6.9 14.6 10.9 8.6 6.7 7.5 12.2 3.8 85.1 3.7 3.0 3.9 5.8 20.0 5.3 4.8 18.8 12.1 8.7 6.4 5.3 7.5 7.3 14.5 3.4 3.6 1.4 1.7 19.2 4.7 5.2 8.2 17.7 7.1 12.9 6.7 10.1 10.5 4.9 8.8 3.7 5.5 4.6 9.8 18.6 6.3 6.7 13.8 6.0 11.9 2.8 15.2 5.4 14.4 3.1 5.6 29.0 1.6 4.8 0.9 1.1 1.5 1.5 3.0 1.1 1.4 1.5 22.7 4.7 7.0 2.4 3.5 2.5 14.8 19.3 25.2 23.4 12.2 11.3 11.1 14.8 19.8 7.6 89.3 113.5 3.0 42.1 16.6 23.6 42.1 163.1 95.0 100.1 40.1 17.7 3.6 1.7 43.2 303.3 25.9 52.7 23.3 74.0 6.2 25.7 185.3 57.9 272.0 39.6 19.1 46.9 22.7 53.9 360.0 30.5 37.9 55.6 12.6 45.6 51.3 79.4 31.3 56.3 11.3 14.4 77.6 50.5 77.4 9.8 15.3 2.2 22.5 31.7 70.1 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3" Q8WU67 18 21650897-21704805 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 54.7;RPMI-8226: 60.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 9.2 5.4 12.0 14.2 10.7 8.6 20.7 19.5 11.1 6.4 34.2 4.8 5.1 23.8 6.0 5.4 12.7 7.8 13.5 7.1 8.8 8.5 8.7 21.7 12.8 21.3 11.5 5.0 9.4 8.8 10.7 11.8 10.8 16.6 6.9 37.1 14.7 10.3 4.1 10.1 3.8 45.3 5.5 12.3 17.9 19.0 4.4 10.8 20.9 12.9 6.7 13.7 9.2 25.5 7.1 6.1 33.0 23.3 7.1 17.6 9.1 7.5 5.5 5.4 3.4 3.4 2.3 0.0 5.0 2.0 3.5 4.8 5.7 7.8 21.7 9.1 1.6 16.0 25.1 8.7 4.1 5.0 13.6 6.0 2.3 9.3 9.8 5.2 10.2 7.9 2.0 4.8 5.2 2.4 1.8 2.3 7.5 6.0 12.9 3.1 3.0 9.9 11.4 2.6 24.2 12.9 54.7 4.1 60.9 9.8 7.3 4.5 2.0 11.3 10.1 2.8 6.1 3.1 18.1 1.8 3.5 5.0 6.1 7.6 14.6 9.4 22.3 4.4 13.4 7.9 29.1 10.2 11.4 11.1 17.9 8.5 7.1 10.0 10.6 6.1 5.1 8.2 10.3 33.0 7.1 23.3 4.2 17.6 9.1 12.0 10.7 19.5 11.1 8.8 8.5 11.5 5.0 16.6 10.8 8.9 9.4 22.4 33.1 29.8 13.4 3.6 45.9 16.0 7.9 3.5 45.2 23.7 1.7 47.1 3.1 9.6 90.1 0.0 24.3 19.9 15.1 42.5 11.5 26.1 56.1 0.0 34.9 12.3 24.7 1.1 6.9 28.6 30.4 17.2 46.9 9.4 35.8 46.5 6.0 7.7 13.6 12.9 15.9 3.5 8.5 13.2 78.8 38.3 23.5 28.7 ABHD6 ENSG00000163686 "Abhydrolase domain containing 6" Q9BV23 3 58237506-58295693 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.4" "Cell type enhanced" "Detected in many" 8 "Hepatocytes: 53.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: AB_2686583" "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favorable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" 8.3 10.0 11.6 4.6 14.0 1.0 5.8 17.7 22.5 3.7 8.1 30.0 10.3 26.3 4.7 10.8 4.8 6.9 4.4 4.1 19.0 9.2 24.3 43.4 6.3 5.2 18.6 12.2 4.1 2.4 4.8 15.2 4.8 19.0 4.4 8.1 10.5 3.0 12.9 3.1 17.2 33.5 6.8 24.0 22.8 9.0 3.1 14.3 2.0 6.6 2.1 5.4 4.6 4.1 3.9 7.0 2.1 9.3 0.7 2.6 1.1 2.0 7.7 1.1 5.0 14.5 2.6 13.4 5.4 4.8 5.7 7.7 4.0 2.8 3.9 0.5 2.9 17.6 6.0 5.2 2.4 5.1 6.6 2.6 3.3 5.2 5.5 4.9 1.0 17.6 2.5 11.1 5.2 2.5 6.7 3.2 6.5 3.9 9.0 4.6 1.5 6.7 0.4 3.7 16.7 17.0 2.5 2.3 8.7 8.7 2.8 6.7 2.7 5.9 3.3 11.1 2.3 2.2 2.7 3.4 4.1 4.5 10.1 6.4 2.6 7.6 0.1 10.5 9.9 5.6 0.0 2.8 2.1 2.1 9.3 2.0 3.9 1.2 2.6 4.6 3.0 1.2 1.5 0.0 0.7 6.2 7.0 1.4 1.1 11.6 14.0 17.7 22.5 19.0 9.2 18.6 12.2 19.0 14.3 0.0 2.6 8.8 2.6 7.7 13.8 4.8 0.0 17.4 5.7 3.5 3.9 2.2 1.7 2.9 0.8 7.8 13.6 0.0 1.6 0.4 2.1 1.3 10.5 53.3 8.1 14.3 0.0 26.4 14.6 0.4 6.4 9.6 3.3 14.4 2.2 10.8 1.6 0.0 7.8 15.4 3.0 0.0 3.5 0.5 2.3 21.5 0.5 3.2 4.5 2.0 AC008397.2 ENSG00000285188 "CAMP-specific 3',5'-cyclic phosphodiesterase 4C " Q08493 19 18207961-18255419 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 22.4;intestine: 15.6;pancreas: 14.2" "Group enriched" "Detected in some" 8 "Alveolar cells type 1: 8.9;Alveolar cells type 2: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.7;U-2197: 1.6;U-87 MG: 4.8" "HPA048975, HPA054218" Uncertain Approved "Midbody ring,Centrosome,Cytosol" NA NA "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 1.9 15.6 0.0 0.0 1.3 1.1 3.6 4.0 1.0 22.4 0.6 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.8 0.0 0.0 1.7 0.0 2.1 1.1 3.7 0.0 8.0 0.6 0.0 0.4 7.1 0.2 0.0 0.0 0.4 0.8 4.1 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.3 0.3 0.4 0.0 0.1 0.5 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.3 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.4 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.7 0.1 0.2 0.0 0.0 0.2 1.6 0.0 0.3 0.2 0.1 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 205.6" "Group enriched" "Detected in many" 25 "Early spermatids: 470.5;Late spermatids: 1015.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "memory B-cell: 3.7" "Group enriched" "Detected in many" 23 "B-cells: 3.7;monocytes: 2.0;T-cells: 1.9" "Group enriched" "Detected in some" 4 "ASC TERT1: 36.7;HUVEC TERT2: 18.7" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 92000000 Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 6.8 2.0 0.5 2.4 4.2 0.0 2.9 0.5 1.1 5.3 83.2 0.7 37.7 46.4 4.5 5.1 1.7 1.5 4.4 4.7 0.6 0.7 2.6 1.4 16.3 2.2 0.4 0.7 1.4 3.0 3.6 3.6 3.6 0.8 3.4 1.4 1.7 2.5 20.1 3.6 1.3 205.6 2.4 0.6 1.4 1.9 32.6 1.3 0.5 6.9 3.1 2.2 1.7 1.6 3.7 0.1 0.0 2.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 1.5 36.7 0.4 1.3 2.7 0.0 0.0 0.5 3.2 0.7 1.1 6.2 0.0 0.0 1.7 0.0 0.0 0.0 0.7 3.5 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.6 18.7 0.0 3.1 0.0 0.0 0.6 0.0 0.8 0.3 6.3 0.4 0.1 0.2 0.5 0.0 0.0 4.6 3.2 0.0 0.0 0.0 0.7 1.6 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.6 0.9 3.7 1.9 1.4 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.5 4.2 0.5 1.1 0.6 0.7 0.4 0.7 0.8 1.3 0.0 3.5 0.0 1.5 1.3 3.1 1.4 0.0 0.0 1.2 0.0 0.0 0.1 0.0 3.4 470.5 13.5 29.6 0.0 0.4 0.1 1.0 6.0 6.9 0.0 4.4 0.0 17.3 2.5 18.5 1015.1 4.0 5.1 3.3 0.0 8.7 1.9 0.7 10.2 2.5 10.7 1.0 0.0 0.9 8.1 3.4 0.1 0.1 0.9 8.6 2.1 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15561033-15602148 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 122.0" "Cell type enhanced" "Detected in many" 13 "Cholangiocytes: 61.1;Enterocytes: 38.8;Proximal tubular cells: 45.6;Sertoli cells: 19.4" "Cancer enhanced" "Detected in many" "renal cancer: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HaCaT: 4.1;Hep G2: 2.5;NB-4: 2.2;RPMI-8226: 2.1;RT4: 2.5;SH-SY5Y: 2.8;SuSa: 1.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" NA NA 85000 "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 4.5 0.4 0.2 0.8 0.2 0.0 2.3 0.2 0.2 0.4 49.1 0.2 2.3 46.0 0.4 2.7 1.2 0.6 16.4 10.5 0.2 0.1 23.2 1.2 0.8 0.6 0.2 0.2 1.3 1.6 0.0 0.2 1.0 0.2 0.5 1.3 0.2 1.1 1.2 0.7 0.2 122.0 0.3 0.2 0.2 0.5 17.9 0.2 0.2 4.5 0.5 0.2 0.4 0.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.4 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.4 4.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.2 0.0 0.0 2.1 0.4 2.5 0.6 2.8 0.1 0.3 0.2 1.9 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.3 2.2 0.5 0.1 0.0 9.8 61.1 0.0 0.0 0.0 0.0 2.9 3.3 0.5 0.4 0.0 38.8 0.0 0.7 0.2 0.0 0.4 0.0 0.8 0.7 0.0 6.9 0.0 0.0 1.1 7.8 0.0 0.0 0.0 1.2 0.0 0.9 4.2 5.6 45.6 0.0 19.4 0.0 1.1 0.7 0.1 10.6 0.0 3.3 1.6 ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333629 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "esophagus: 14.3;skin 1: 38.2;tongue: 17.3" "Cell type enhanced" "Detected in some" 23 "Melanocytes: 1.7;Spermatocytes: 1.8;Suprabasal keratinocytes: 5.1" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MCF7: 2.2;T-47d: 8.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 2.2 0.1 0.1 3.8 0.1 0.1 0.1 0.0 0.4 0.1 14.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 1.1 0.0 0.1 1.4 0.1 0.2 38.2 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 17.3 3.5 0.1 2.2 0.6 0.4 0.4 0.2 1.0 3.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 8.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.1 0.2 0.0 3.6 0.1 3.5 1.6 0.0 0.6 2.3 2.3 0.4 1.0 0.2 0.4 2.0 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 1.8 0.5 5.1 0.0 0.0 0.0 0.1 ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409059-19452020 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0;urinary bladder: 31.3;vagina: 40.6" "Cell type enhanced" "Detected in some" 11 "Cone photoreceptor cells: 2.0;Early spermatids: 2.1;Ito cells: 1.8;Late spermatids: 1.8;Syncytiotrophoblasts: 3.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "intermediate monocyte: 3.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "BEWO: 16.7;RT4: 41.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 17.4 1.7 3.1 0.7 5.9 0.4 20.7 2.3 6.8 1.4 3.5 0.9 5.3 3.0 1.3 3.0 1.8 2.8 1.3 3.2 3.0 1.9 1.6 2.6 1.5 0.6 4.4 0.3 1.3 4.7 2.7 1.6 20.0 4.5 9.4 3.1 1.4 1.8 6.8 2.1 4.0 1.7 2.1 2.9 1.2 41.0 1.3 4.7 0.4 1.8 1.0 0.8 31.3 40.6 1.0 1.2 0.0 3.1 0.0 1.0 0.5 0.6 1.3 2.1 1.1 3.5 0.2 16.7 1.1 0.8 0.5 0.5 0.3 1.0 0.7 0.4 0.1 0.2 2.5 0.5 3.3 0.9 1.4 0.6 1.1 1.0 1.5 0.7 0.2 1.1 1.1 3.1 1.3 1.4 0.3 3.5 1.2 1.7 2.1 1.2 1.0 1.9 0.9 1.6 6.0 0.5 1.7 0.6 0.4 0.3 41.0 3.9 0.9 0.2 1.1 0.2 5.6 1.4 1.4 1.7 0.3 0.8 0.3 0.5 0.7 0.9 0.8 0.3 0.8 0.7 0.0 0.1 0.0 0.8 3.1 0.2 1.0 0.3 0.3 0.3 0.4 1.0 0.2 0.0 0.0 0.0 1.2 0.3 0.5 3.1 5.9 2.3 6.8 3.0 1.9 4.4 0.3 4.5 4.7 0.0 0.0 0.0 0.2 0.2 0.6 0.1 0.0 0.0 0.0 0.0 2.0 0.4 0.0 0.1 2.1 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.5 0.0 3.3 0.0 0.0 0.5 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 43.8;skeletal muscle: 98.2" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 45.5;Erythroid cells: 46.7;Exocrine glandular cells: 34.7;Horizontal cells: 52.4;Paneth cells: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.2;CACO-2: 12.9;K-562: 15.2;Karpas-707: 25.2;U-2 OS: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 650000 "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.8 5.8 3.5 16.1 10.3 1.4 22.8 11.8 1.4 4.2 2.7 1.4 5.7 1.9 2.6 2.8 1.8 3.1 4.5 5.5 43.8 1.4 1.8 1.8 5.9 22.2 4.8 1.7 1.6 7.0 3.2 2.0 37.9 3.3 3.4 4.6 6.5 3.3 98.2 1.4 7.9 1.9 8.7 2.3 2.1 1.9 2.6 3.5 1.6 15.9 3.2 2.1 1.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.3 0.2 0.5 0.0 8.2 0.3 0.0 0.1 0.2 12.9 0.3 0.0 0.5 0.0 1.2 0.4 2.2 0.1 0.0 4.4 0.5 0.2 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.1 15.2 25.2 0.1 3.6 0.0 0.1 1.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 1.4 0.0 1.0 0.0 3.7 0.0 0.0 0.1 0.7 6.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 16.1 22.8 11.8 5.5 43.8 22.2 4.8 37.9 2.6 0.0 0.0 0.0 21.7 0.7 7.2 4.5 0.0 0.0 0.0 0.0 0.0 5.4 0.0 6.2 0.0 2.3 45.5 46.7 34.7 1.9 4.2 17.2 0.0 0.0 0.7 52.4 3.4 1.3 0.0 0.0 0.6 0.0 1.7 8.2 7.6 11.9 30.0 52.6 0.7 1.0 4.3 0.0 3.3 3.9 4.5 0.9 5.9 0.0 3.3 11.2 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537114-73543794 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.6" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 18.2;T-47d: 25.1" HPA043705 Approved Approved Mitochondria NA NA Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 8.5 7.2 5.1 3.7 3.9 1.0 13.7 2.0 7.7 3.0 5.8 4.1 0.9 5.3 6.8 8.8 2.7 3.4 1.8 11.3 4.3 3.6 16.4 27.6 9.0 0.9 3.2 6.0 4.5 1.4 2.9 0.9 4.1 5.6 5.5 3.4 2.4 2.7 6.1 10.7 3.8 12.9 13.0 1.9 1.0 3.4 2.7 2.4 0.9 1.8 5.0 1.9 5.6 1.7 3.8 5.7 1.0 1.7 4.2 6.3 3.1 4.2 5.0 1.9 0.1 9.9 6.1 0.1 1.3 5.4 4.5 8.2 1.9 2.1 0.0 0.0 3.6 0.0 2.5 0.0 0.9 2.2 2.3 1.6 2.7 1.2 18.2 9.6 0.1 3.0 7.9 0.4 3.6 0.0 0.1 2.0 0.0 0.0 0.0 3.5 1.6 0.3 0.5 1.9 0.6 1.9 5.1 3.9 0.1 4.4 4.7 2.3 3.8 4.2 12.4 6.8 0.4 25.1 6.2 2.2 2.5 3.2 2.3 0.0 0.0 0.0 1.3 3.6 0.0 4.0 0.1 1.3 1.0 6.0 1.7 4.9 3.8 5.5 4.7 5.7 2.6 4.8 5.3 0.2 4.2 1.5 3.2 6.3 3.1 5.1 3.9 2.0 7.7 4.3 3.6 3.2 6.0 5.6 2.4 0.0 2.7 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.4 0.0 0.0 0.0 7.2 0.2 0.3 0.0 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 1.7 0.0 0.4 0.8 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.0 0.0 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81330005-81394179 "Enzymes, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 49.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 37.1" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.0;CACO-2: 2.5;Karpas-707: 1.8;SK-MEL-30: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA037723, HPA037724" Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA037723: AB_10672606, HPA037724: AB_2675631" "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.2 49.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.5 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 1.8 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 5.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.4 0.0 0.0 0.6 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 60.5" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 41.4 16.5 5.9 6.4 5.3 2.7 13.4 3.3 8.7 7.8 11.9 4.6 4.0 12.8 13.9 10.6 9.4 8.3 8.8 35.1 4.5 4.0 25.0 60.5 6.2 4.4 4.3 5.4 6.2 8.1 6.4 2.7 7.9 4.3 8.5 6.2 6.9 7.3 6.8 50.7 3.9 12.0 16.3 3.2 4.3 7.4 5.7 3.7 5.3 7.4 11.6 3.9 11.3 4.6 9.7 13.8 1.8 4.4 9.0 19.0 8.1 11.2 11.0 2.3 9.7 10.3 4.0 0.4 6.0 14.0 9.8 13.0 7.8 7.5 0.0 4.4 3.2 5.1 6.2 0.0 0.6 5.2 14.2 13.9 6.8 4.5 26.8 6.7 0.0 19.3 9.1 0.0 3.7 0.0 9.6 4.2 0.0 0.0 0.0 8.4 4.7 1.0 7.7 3.3 1.3 16.7 16.1 9.8 0.1 3.6 4.7 10.1 12.2 14.8 11.5 12.0 1.1 27.6 5.4 7.6 8.6 21.6 5.5 5.7 0.0 0.0 4.0 7.2 0.0 8.1 1.5 3.7 1.8 14.6 4.4 10.7 9.7 13.7 11.1 13.8 7.9 12.4 13.5 0.1 9.0 3.9 8.5 19.0 8.1 5.9 5.3 3.3 8.7 4.5 4.0 4.3 5.4 4.3 3.7 0.0 5.4 1.7 1.0 1.4 0.9 43.0 7.6 4.0 1.2 7.0 9.8 4.6 11.6 18.3 1.0 3.6 16.2 0.0 29.2 2.3 3.9 0.3 13.8 25.8 13.9 1.6 15.1 3.7 4.0 0.4 5.5 2.0 5.0 30.7 15.1 3.3 19.0 5.8 7.8 16.5 4.5 6.5 4.2 0.4 4.3 0.4 6.9 5.7 19.7 0.4 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591706-73596496 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.6" "Cell type enhanced" "Detected in many" 11 "Hepatocytes: 22.2;Proximal tubular cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.3;MCF7: 5.6;SK-BR-3: 11.7;T-47d: 29.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 6.3 2.2 2.9 1.4 3.6 0.6 4.4 1.6 5.7 3.6 2.6 1.0 1.5 3.9 1.0 2.4 2.0 0.9 3.3 2.9 2.1 2.0 13.0 15.6 3.9 1.1 1.6 2.8 0.9 2.2 1.1 0.7 4.9 2.7 1.4 3.1 1.8 3.1 3.4 0.7 0.9 7.4 2.5 0.8 1.4 1.9 2.8 0.9 0.3 1.2 0.8 1.2 1.1 1.3 1.7 0.6 5.0 0.4 4.6 10.6 3.2 4.3 1.2 0.1 0.0 0.5 0.2 0.0 0.3 0.0 0.3 0.5 0.1 7.3 0.0 0.2 0.4 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 1.6 0.0 0.8 0.0 4.1 0.3 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 5.6 0.1 0.8 0.4 1.5 1.2 0.0 0.0 0.0 0.1 2.1 0.6 0.2 2.8 11.7 0.8 0.0 29.2 4.4 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 1.0 10.6 0.4 5.5 1.6 5.2 6.0 0.2 1.7 3.2 6.5 0.3 4.6 0.2 0.6 4.8 3.2 2.9 3.6 1.6 5.7 2.1 2.0 1.6 2.8 2.7 0.9 0.0 2.4 2.2 1.0 0.2 0.2 1.2 2.5 2.7 1.2 10.4 0.0 11.8 13.3 3.6 1.6 0.3 10.3 0.0 8.3 11.5 1.1 0.5 5.7 22.2 10.2 1.6 0.0 0.0 2.7 3.8 0.3 1.7 0.0 1.8 2.7 0.5 4.8 2.9 0.4 51.8 0.5 0.0 0.9 2.7 14.3 0.3 3.8 4.4 2.8 1.1 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6394391 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" 8 "granulocytes: 137.0;Late spermatids: 118.5;Proximal tubular cells: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "NK-cell: 20.5;plasmacytoid DC: 19.4" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 20.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 29000 Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 4.7 13.3 25.8 10.8 29.8 7.7 3.9 23.9 50.0 4.4 18.3 11.3 0.5 33.2 5.1 3.8 14.3 4.4 5.3 6.3 27.8 43.9 29.4 9.1 8.6 12.3 36.0 20.7 5.3 4.0 1.9 18.5 7.4 49.9 5.6 13.5 6.6 4.1 4.9 1.5 9.4 33.2 14.3 14.2 8.9 6.2 13.1 6.9 9.0 2.3 6.5 11.6 9.1 6.6 1.0 19.4 0.4 0.6 20.5 4.4 2.8 23.7 20.7 20.4 22.0 4.7 7.8 7.7 20.5 10.6 30.4 18.2 71.4 7.7 29.1 15.1 16.6 23.5 23.5 32.9 54.7 11.4 25.5 28.7 15.3 16.4 25.3 19.3 17.9 12.7 6.9 10.5 25.1 29.8 8.1 17.0 36.5 12.4 6.3 16.0 27.7 37.3 19.0 10.2 23.9 48.0 44.6 23.5 19.7 17.1 9.1 11.2 31.7 18.4 28.3 65.2 10.5 10.1 8.4 27.5 27.7 16.2 27.4 32.3 5.3 21.6 40.9 17.5 31.3 16.8 0.0 0.1 0.1 4.1 0.6 1.0 1.0 3.4 3.6 2.9 0.4 1.2 2.3 0.4 20.5 0.5 19.4 4.4 2.8 25.8 29.8 23.9 50.0 27.8 43.9 36.0 20.7 49.9 6.9 6.0 25.5 13.7 13.3 28.2 33.6 8.1 12.7 1.4 7.9 8.7 9.8 15.1 13.3 19.1 73.6 15.6 70.9 0.0 6.2 23.1 14.2 7.0 137.0 13.4 26.8 44.5 4.6 5.5 4.0 118.5 3.4 16.9 37.1 25.2 88.8 10.6 16.5 29.1 6.7 214.2 15.6 0.0 6.2 38.2 26.7 25.7 14.4 21.4 48.7 19.5 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 7.0 22.6 23.5 10.9 24.3 16.5 8.7 14.4 32.6 6.8 17.1 13.5 9.9 23.3 6.5 13.1 15.8 12.2 10.1 27.0 22.8 19.3 15.3 19.0 9.7 12.1 22.1 19.0 8.3 17.4 5.9 11.4 8.1 19.5 9.6 14.3 10.4 14.4 7.3 21.7 16.7 22.2 7.3 14.6 9.1 16.7 12.8 11.1 17.1 12.4 8.6 12.2 10.9 7.2 20.5 27.0 31.0 26.2 11.2 22.5 18.8 7.7 9.3 3.2 6.4 9.0 5.5 5.6 5.3 4.3 7.4 6.9 13.6 10.8 9.7 23.9 7.2 17.1 15.2 6.1 13.1 2.5 7.2 10.7 9.7 12.5 13.0 8.1 9.3 9.1 6.4 10.1 7.1 5.1 11.0 4.5 11.4 8.6 12.1 5.2 21.8 13.2 12.1 5.6 15.2 24.9 6.4 5.9 17.4 7.8 8.8 11.0 5.2 11.6 29.8 18.1 5.2 16.4 22.8 5.2 18.3 4.1 9.4 8.7 10.3 15.2 6.1 22.7 9.8 9.7 20.0 26.2 31.0 18.8 25.0 17.1 20.5 18.1 17.0 27.0 19.3 16.1 17.3 18.7 11.2 23.4 17.0 22.5 18.8 23.5 24.3 14.4 32.6 22.8 19.3 22.1 19.0 19.5 11.1 32.8 13.1 13.4 10.4 5.5 17.5 9.4 10.2 17.4 9.1 12.2 15.7 27.1 54.7 19.6 30.4 8.2 74.4 0.0 18.1 16.7 7.2 11.9 13.9 22.2 24.7 7.9 18.5 11.6 16.5 58.7 9.2 13.0 10.1 26.2 34.3 15.2 19.9 59.6 8.1 57.5 19.5 12.9 8.5 25.9 8.7 6.9 16.2 14.6 27.0 11.6 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 913.9;Late spermatids: 1666.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol NA NA 3700000 Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 22.3 59.7 38.0 20.8 40.3 38.0 33.0 27.9 43.7 23.1 29.7 27.4 24.4 31.1 25.2 36.2 24.8 29.5 26.9 27.4 34.6 33.7 42.1 54.8 24.7 29.4 31.5 34.6 33.7 53.0 28.4 43.9 39.7 39.7 27.0 32.8 28.5 46.0 23.8 35.4 21.6 34.5 24.2 28.6 28.1 34.2 38.3 21.2 33.0 32.5 32.8 29.8 22.7 20.3 33.9 20.3 17.3 23.0 35.3 41.0 33.1 17.8 26.6 41.5 22.8 18.8 18.8 33.7 21.7 23.1 21.7 19.2 36.5 18.0 11.2 16.9 20.3 28.5 17.5 40.3 23.6 19.6 27.3 41.0 32.8 24.1 79.8 26.1 37.2 18.9 19.2 21.5 20.3 25.2 23.0 24.6 42.0 33.1 21.9 25.6 24.2 40.0 36.0 50.1 47.2 30.0 26.6 42.1 25.6 33.9 25.5 45.3 44.8 13.5 32.0 43.4 28.3 18.9 19.9 20.3 23.9 15.9 19.7 32.7 29.8 59.1 34.9 28.3 32.2 28.1 17.3 19.8 17.1 30.1 22.7 39.7 33.9 34.3 34.4 17.7 31.1 41.0 39.7 3.5 35.3 23.0 20.3 35.6 33.1 38.0 40.3 27.9 43.7 34.6 33.7 31.5 34.6 39.7 21.2 41.7 88.5 101.3 80.3 70.3 51.3 74.2 109.5 129.8 67.1 64.6 7.9 179.7 228.8 194.3 913.9 64.7 84.9 163.5 146.5 234.8 71.9 111.0 68.2 112.0 123.7 27.0 79.2 50.3 57.7 1666.6 87.5 74.7 77.6 116.4 107.9 64.8 155.5 108.7 86.7 241.7 43.6 90.5 79.3 111.8 121.7 79.7 157.0 93.8 114.3 108.3 ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hofbauer cells: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 30.3" "Lineage enriched" "Detected in all" 5 "monocytes: 30.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 8100 "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" 15.7 23.6 13.1 13.9 13.6 3.6 13.0 12.5 19.5 11.3 15.4 11.7 15.4 26.9 10.5 20.0 8.9 9.3 12.4 18.1 14.4 18.2 18.7 65.4 13.3 40.7 11.8 12.7 8.1 36.2 13.6 13.8 31.3 12.2 15.3 11.7 16.4 32.3 18.5 10.1 7.0 24.4 10.8 11.0 18.9 14.2 14.6 7.1 10.0 12.4 9.6 9.7 14.3 8.0 1.0 6.6 4.6 30.3 3.8 5.6 4.2 6.8 14.2 13.8 12.2 12.4 6.2 10.7 11.3 20.2 20.7 21.6 9.8 11.2 1.8 9.3 14.4 6.2 10.1 7.2 10.4 10.0 35.2 12.4 4.6 20.9 10.2 17.2 6.8 11.8 15.1 6.6 10.7 6.3 12.5 14.9 6.2 8.3 14.8 13.5 11.1 5.6 6.1 9.5 10.4 8.6 4.4 18.7 14.9 15.5 16.0 7.3 11.4 15.6 34.8 8.0 7.5 21.2 6.0 8.8 10.5 8.8 13.7 16.1 12.4 16.0 1.5 15.5 3.4 16.1 4.6 7.2 3.0 5.6 30.3 4.4 1.0 3.5 5.0 6.6 0.7 3.1 2.7 1.2 3.8 19.5 0.2 3.6 4.2 13.1 13.6 12.5 19.5 14.4 18.2 11.8 12.7 12.2 7.1 17.9 18.1 4.5 10.0 3.7 13.1 7.3 20.4 10.7 7.9 17.4 5.9 36.5 8.3 47.8 1.4 13.9 43.0 0.0 52.7 28.2 10.4 9.4 11.5 74.2 103.8 11.1 14.5 48.5 51.1 1.7 4.6 17.1 23.6 43.3 23.6 21.3 29.5 28.1 9.9 23.4 11.5 19.4 7.5 9.7 17.0 2.0 24.5 7.5 10.9 5.1 ACP4 ACPT ENSG00000142513 "Acid phosphatase 4" Q9BZG2 19 50790415-50795224 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Hydrolase "Amelogenesis imperfecta, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 4.2;testis: 4.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 4.4;Karpas-707: 2.9;U-266/84: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "unprognostic (9.41e-2)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (3.70e-3)" "unprognostic (7.62e-2)" "unprognostic (3.18e-2)" "unprognostic (3.89e-3)" "unprognostic (5.46e-2)" "unprognostic (2.47e-1)" "unprognostic (5.59e-2)" "unprognostic (3.96e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-3)" "unprognostic (2.36e-1)" "unprognostic (4.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.5 0.3 0.8 0.0 0.5 0.2 0.9 1.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 2.2 0.2 0.8 0.1 0.0 0.1 0.6 0.0 0.0 0.0 1.6 4.4 0.1 1.3 0.7 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 2.9 0.0 0.9 0.7 1.4 0.5 0.8 1.5 1.0 0.4 0.6 0.0 1.6 0.4 0.6 0.3 0.3 0.7 0.1 0.1 1.0 0.0 0.7 0.6 0.8 0.4 0.7 5.4 0.6 0.7 0.9 0.3 0.0 0.1 0.0 0.2 0.5 0.8 0.8 0.6 0.5 0.0 0.9 0.8 0.5 0.0 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 117.9;lung: 151.9" "Cell type enhanced" "Detected in many" 12 "Hofbauer cells: 439.8;Ito cells: 434.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "memory B-cell: 51.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BEWO: 14.6;BJ hTERT+: 9.8;K-562: 10.3;RPMI-8226: 13.9;SK-MEL-30: 41.4;U-138 MG: 38.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 3700000 Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 117.9 2.8 0.9 21.1 1.1 1.4 7.7 0.7 1.0 11.9 10.2 1.2 2.1 7.7 7.7 6.5 12.1 3.5 9.1 6.8 0.9 0.4 28.0 16.3 151.9 30.8 1.0 1.0 13.2 8.7 0.2 1.6 9.2 1.2 6.4 8.7 19.1 8.6 2.8 3.0 10.4 15.6 3.3 1.9 20.7 15.0 3.5 0.7 9.2 2.2 8.2 18.4 11.4 10.1 51.4 13.9 16.8 9.4 2.6 16.0 8.1 3.3 0.4 0.0 0.0 0.2 0.0 14.6 0.4 9.8 0.0 0.0 0.0 0.1 0.5 0.6 2.9 2.4 0.1 0.0 1.5 0.0 3.7 0.3 0.1 0.0 1.8 0.6 0.0 0.2 0.0 1.1 0.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.7 0.3 0.5 0.3 0.1 0.3 0.1 0.7 13.9 0.0 0.1 0.2 0.3 0.0 0.0 41.4 0.4 0.0 0.1 0.3 38.9 0.4 0.7 0.1 0.2 1.8 0.2 8.0 0.0 1.2 0.0 9.4 16.8 4.1 9.1 2.1 51.4 6.4 4.7 1.7 23.5 8.3 4.7 2.6 2.6 8.7 13.9 16.0 8.1 0.9 1.1 0.7 1.0 0.9 0.4 1.0 1.0 1.2 0.7 8.9 8.5 68.7 8.2 9.2 6.0 1.1 22.9 2.7 2.3 7.0 17.7 29.7 8.3 1.6 0.1 2.9 5.9 0.0 9.9 23.7 12.1 16.2 65.4 6.4 439.8 1.6 2.9 434.6 101.6 0.0 1.7 100.7 13.5 131.7 4.5 43.7 4.7 21.0 11.3 91.3 31.7 0.0 3.2 0.0 0.1 9.7 21.9 25.4 8.3 4.3 ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670496 "Enzymes, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 38.9;RPTEC TERT1: 44.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" NA NA 64000 "HPA028560: AB_10602427" "unprognostic (3.17e-2)" "unprognostic (3.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.87e-2)" "unprognostic (3.85e-1)" "unprognostic (8.50e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (3.94e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "prognostic favorable (6.44e-4)" 6.0 14.5 8.8 6.6 10.7 4.7 19.3 10.5 9.1 12.6 10.5 7.6 13.1 7.7 10.0 17.6 8.1 13.9 13.6 8.5 13.0 6.0 17.0 13.3 7.6 3.8 10.2 8.0 11.6 18.5 18.1 22.5 4.4 11.6 13.6 10.2 12.7 12.3 19.2 7.6 9.2 8.9 9.7 11.2 6.6 12.8 8.2 12.7 10.8 20.7 5.8 9.7 16.8 6.9 2.9 4.8 11.5 2.2 0.3 12.4 2.6 7.4 3.1 2.6 4.6 1.7 1.6 7.5 1.7 5.4 5.5 6.5 3.6 11.6 2.1 6.5 3.7 4.2 13.0 3.5 11.6 5.7 2.9 5.8 7.8 4.4 6.8 5.0 1.4 0.3 2.4 8.6 2.8 5.8 6.6 5.5 11.0 3.6 1.2 6.2 5.5 5.7 3.6 6.2 38.9 23.0 4.1 2.2 25.2 44.4 14.9 2.2 2.6 6.3 4.6 12.8 6.2 7.4 2.1 3.8 1.7 3.3 0.3 5.4 4.9 7.3 0.9 3.2 0.1 9.4 0.0 2.2 11.5 4.3 0.7 7.5 2.5 7.2 5.8 4.8 2.9 8.0 6.9 3.3 0.3 0.3 3.0 12.4 2.6 8.8 10.7 10.5 9.1 13.0 6.0 10.2 8.0 11.6 12.7 17.9 11.5 0.0 4.7 1.0 1.9 5.6 15.3 14.7 4.5 15.7 0.0 17.2 14.9 6.8 4.7 2.2 3.8 0.0 13.3 5.8 2.0 5.7 1.1 9.6 4.0 0.0 8.7 5.5 3.7 0.9 5.5 3.9 3.3 3.6 8.1 11.8 14.6 5.8 3.9 12.4 1.0 12.9 3.1 3.9 4.4 1.1 6.8 5.7 8.4 5.1 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 15.2;lymphoid tissue: 6.1;skin 1: 14.1;tongue: 5.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 21.5;U-87 MG: 28.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" NA NA "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.3 0.3 1.6 0.3 5.5 0.3 1.0 15.2 5.4 0.9 0.3 4.2 0.3 0.4 0.4 1.4 1.1 0.3 0.9 0.3 2.5 1.2 0.3 0.3 0.4 0.3 6.5 0.7 0.3 0.3 0.3 0.0 0.3 5.2 1.2 0.3 0.0 0.6 0.3 0.3 14.1 0.3 0.3 4.1 0.3 0.6 0.4 5.3 0.0 0.3 5.5 6.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.5 0.3 3.2 0.0 0.0 0.0 21.5 0.2 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.9 0.7 0.0 0.0 0.0 0.0 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 15.2 5.4 2.5 1.2 6.5 0.7 5.2 5.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACPP "ACP-3, ACP3, PAP" ENSG00000014257 "Acid phosphatase, prostate" P15309 3 132317367-132368298 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "prostate: 345.2" "Cell type enriched" "Detected in many" 135 "Glandular cells: 2098.0" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 43.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.2;OE19: 12.7;RPMI-8226: 32.4;U-698: 9.4;U-87 MG: 9.0" "Low region specificity" "Detected in some" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 9200 "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 0.4 0.6 0.4 0.7 1.6 1.4 0.8 0.3 0.7 3.9 0.4 0.2 0.0 0.4 0.3 2.5 14.7 0.6 0.2 0.9 0.3 0.3 6.2 0.3 2.0 2.7 0.6 0.8 0.4 0.8 0.5 0.3 5.3 0.7 345.2 0.7 0.8 9.1 0.2 0.3 2.5 0.4 0.4 2.2 1.0 0.5 1.0 0.6 0.2 1.3 6.6 6.8 0.5 1.5 0.2 11.2 43.1 9.7 0.9 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.6 7.0 0.1 10.2 0.0 0.0 0.2 0.2 5.7 0.4 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 1.2 0.2 0.1 0.1 4.1 0.1 0.6 0.8 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.1 0.1 0.0 7.8 0.4 12.7 1.2 0.0 0.0 32.4 3.1 3.8 0.0 2.5 0.0 1.2 0.3 1.1 0.2 3.7 0.0 0.0 0.1 1.5 0.0 0.4 0.2 9.4 9.0 7.3 0.1 0.0 9.7 43.1 0.0 8.6 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.0 8.5 0.9 7.7 0.8 0.0 2.9 0.4 1.6 0.3 0.7 0.3 0.3 0.6 0.8 0.7 0.6 0.0 10.7 0.0 13.0 0.8 0.0 0.5 0.0 0.0 4.5 7.0 0.0 9.6 0.0 1.1 0.0 0.0 1.0 0.0 1.6 1.0 0.8 2098.0 0.0 0.0 4.1 0.0 15.5 0.0 9.2 0.0 0.0 2.8 0.0 0.0 2.4 0.3 1.2 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 7.4 0.0 1.0 11.5 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745334 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "testis: 106.3" "Cell type enriched" "Detected in some" 4 "Early spermatids: 388.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.0;Hep G2: 1.8;HUVEC TERT2: 1.1;NTERA-2: 1.7;TIME: 1.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048687 Enhanced "Secreted in male reproductive system" NA NA "HPA048687: AB_2680494" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 0.9 0.0 0.2 0.2 0.3 0.0 0.6 0.2 0.3 0.2 0.2 0.2 0.2 0.1 0.3 0.7 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.3 0.6 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.4 0.2 0.2 0.2 0.2 0.2 0.2 1.2 0.0 106.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 1.5 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.3 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 388.8 1.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 8.6 0.0 86.9 3.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.5 0.0 0.0 6.5 0.0 28.8 1.7 0.0 0.0 0.0 1.5 0.1 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983278-51989202 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 53.3;kidney: 91.6;liver: 77.8" "Cell type enhanced" "Detected in many" 12 "Enterocytes: 70.2;Erythroid cells: 23.3;Proximal tubular cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB003695, HPA036174, HPA036175" Enhanced NA NA 28000000 "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" 4.4 8.5 2.5 3.9 3.0 1.5 4.4 1.5 3.3 3.2 24.9 4.1 9.8 34.5 1.9 7.9 3.8 3.0 8.4 4.1 2.3 1.8 91.6 77.8 3.5 6.3 2.8 2.9 2.1 9.0 6.2 1.9 4.3 2.9 3.7 6.2 6.6 9.4 9.2 7.6 2.6 53.3 2.1 3.5 3.4 4.9 1.5 1.7 0.6 5.9 6.7 4.1 3.3 2.5 5.0 12.1 3.8 10.0 12.1 6.4 4.5 3.9 8.0 3.9 10.8 9.0 12.1 12.8 4.2 7.9 9.3 5.1 12.4 20.8 2.5 3.5 7.3 3.4 4.9 4.0 25.6 3.7 6.9 5.1 8.9 4.6 38.3 16.6 6.0 5.8 14.0 21.2 8.2 22.1 7.6 3.5 4.4 13.4 7.9 9.1 11.1 0.0 11.0 5.7 25.3 13.6 3.1 3.3 22.5 24.3 15.0 5.5 5.0 5.3 17.5 9.2 1.6 14.1 7.9 1.7 6.7 6.4 8.3 4.9 20.9 4.9 3.8 7.8 12.5 8.0 3.8 10.0 0.2 6.4 9.0 3.6 5.0 2.0 2.8 12.1 4.0 3.3 4.0 0.0 12.1 3.4 1.9 2.7 4.5 2.5 3.0 1.5 3.3 2.3 1.8 2.8 2.9 2.9 1.7 3.0 2.7 0.8 0.8 0.6 0.0 0.1 2.5 2.7 3.4 5.2 0.0 3.3 8.3 12.2 0.2 0.5 70.2 23.3 7.4 3.7 0.8 0.5 6.9 10.9 1.7 0.0 2.4 1.8 2.1 0.4 0.6 2.4 0.0 16.2 9.3 0.8 12.6 21.0 0.0 35.6 0.9 0.0 0.5 0.0 0.2 0.4 3.4 1.5 12.1 0.3 ACY3 "ACY-3, HCBP1, MGC9740" ENSG00000132744 "Aminoacylase 3" Q96HD9 11 67642555-67650659 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 72.2;kidney: 28.9" "Cell type enriched" "Detected in many" 6 "Proximal tubular cells: 163.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 21.1" "Group enriched" "Detected in many" 6 "dendritic cells: 5.9;monocytes: 21.1" "Cell line enhanced" "Detected in some" "CACO-2: 6.1;CAPAN-2: 9.5;Daudi: 34.5;OE19: 9.6;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "HPA039219, HPA048187" Enhanced NA NA "HPA039219: AB_10671872, HPA048187: AB_2680306" "unprognostic (8.37e-3)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.80e-4)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (1.43e-1)" "unprognostic (7.37e-4)" "unprognostic (2.44e-3)" "unprognostic (1.15e-1)" "unprognostic (3.21e-1)" "unprognostic (2.63e-3)" "unprognostic (1.07e-1)" "unprognostic (8.24e-2)" "unprognostic (2.68e-2)" "unprognostic (1.48e-3)" 0.1 0.1 3.4 1.8 5.5 0.6 0.5 0.8 7.8 5.5 13.0 15.3 0.2 38.2 0.3 2.1 0.7 0.4 6.1 0.1 3.1 2.9 28.9 18.3 0.2 3.1 4.6 5.1 0.1 11.2 0.0 0.3 0.1 7.1 0.4 2.2 0.3 1.2 0.2 0.1 0.1 72.2 0.1 5.2 0.9 5.9 0.1 2.8 0.7 0.2 0.0 4.2 0.2 0.2 1.1 5.9 0.0 21.1 2.3 0.9 1.2 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.1 9.5 34.5 0.4 0.0 0.9 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 1.2 1.5 0.0 9.6 0.0 1.1 0.0 6.0 0.0 0.0 0.0 0.1 0.2 0.8 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.8 0.3 0.0 0.5 0.0 0.1 4.9 0.5 1.0 0.2 0.1 2.6 1.1 0.9 0.6 0.0 2.3 21.1 5.9 0.0 1.2 3.4 5.5 0.8 7.8 3.1 2.9 4.6 5.1 7.1 2.8 0.0 1.7 6.3 0.1 0.0 0.0 0.4 10.2 0.0 1.2 21.0 0.0 0.2 26.6 3.5 0.0 0.0 11.8 0.0 9.0 0.2 0.0 0.6 0.0 17.9 1.7 0.0 1.2 0.0 0.3 0.0 0.0 0.9 5.0 0.0 25.1 0.0 6.8 5.9 0.0 163.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 6.6 0.8 ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053221-75069483 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034944 Approved Approved Nucleoplasm,Cytosol NA NA 92000 Cytosol Nucleoplasm "HPA034944: AB_10669898" "prognostic favorable (1.17e-4)" "unprognostic (3.83e-3)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.14e-7)" "unprognostic (5.48e-2)" "unprognostic (4.40e-1)" "unprognostic (1.64e-2)" "unprognostic (1.37e-3)" "unprognostic (3.56e-2)" "unprognostic (4.74e-2)" "unprognostic (6.69e-3)" "unprognostic (9.39e-2)" "unprognostic (1.07e-1)" "unprognostic (5.32e-3)" 8.7 27.4 23.0 13.9 20.4 12.7 16.2 24.0 25.2 10.6 14.9 14.8 14.3 11.3 10.2 26.9 11.6 21.4 7.1 10.8 19.9 30.2 12.2 5.2 10.9 17.6 28.7 19.3 9.1 7.0 8.9 38.2 10.4 24.4 10.0 19.8 9.4 9.7 12.9 22.3 24.4 11.3 11.4 27.5 10.9 14.0 16.7 22.9 8.3 20.2 10.3 19.0 7.5 12.0 10.6 7.6 12.3 6.6 10.0 17.8 5.1 24.8 13.7 19.8 12.1 8.0 9.4 11.0 14.3 5.6 14.6 20.8 13.8 28.1 27.5 8.8 5.9 8.7 22.4 13.0 6.3 23.9 39.9 16.0 17.8 36.1 9.7 4.8 11.2 18.7 5.2 9.1 20.1 10.4 9.4 19.1 26.1 14.0 33.2 19.1 17.0 25.1 20.9 6.0 21.8 13.8 20.2 26.1 12.8 20.5 13.2 36.3 14.7 9.8 6.7 22.2 9.8 14.8 11.1 9.0 10.0 18.5 20.1 15.3 7.9 16.0 28.8 15.3 13.2 10.7 3.9 2.2 12.3 8.6 4.3 9.7 10.0 14.5 9.9 3.8 10.6 12.2 11.3 0.9 10.0 6.6 7.6 17.8 5.1 23.0 20.4 24.0 25.2 19.9 30.2 28.7 19.3 24.4 22.9 6.0 7.8 18.2 36.9 25.4 31.8 17.9 35.7 80.3 19.4 62.8 11.8 19.4 33.2 16.7 18.7 25.1 15.8 70.0 16.2 27.5 20.2 16.2 11.5 4.3 19.1 41.3 28.9 6.7 3.8 7.0 15.5 11.7 37.1 10.0 22.3 16.1 18.0 20.1 15.6 17.3 29.9 25.8 25.8 90.7 15.8 21.0 11.4 22.3 32.3 31.1 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 116.4" "Cell type enhanced" "Detected in all" 6 "Cardiomyocytes: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 12.9 24.0 31.0 4.6 33.9 5.6 10.1 15.5 29.3 6.7 6.2 19.4 4.4 6.2 6.7 10.5 6.6 7.1 7.3 39.6 29.1 28.4 8.8 18.7 7.2 7.5 35.7 18.2 5.7 10.3 9.1 9.7 5.9 28.1 10.4 4.8 6.3 11.5 8.4 116.4 6.6 5.6 6.9 35.7 7.8 7.5 6.5 22.7 3.5 8.2 22.9 6.4 8.2 4.1 20.9 23.7 24.1 10.2 12.6 15.9 8.9 7.7 4.3 4.6 3.8 16.8 13.3 4.2 9.3 7.0 5.8 5.1 1.0 5.6 15.1 24.7 9.2 5.8 6.6 2.5 7.8 5.4 13.0 10.3 11.6 4.7 11.5 6.9 9.7 5.6 9.6 14.6 4.1 6.9 11.8 2.6 7.8 4.8 8.1 12.2 4.9 6.0 12.0 5.2 6.1 5.4 4.8 4.4 8.5 13.6 7.1 13.3 8.8 11.3 7.1 4.2 1.8 2.6 8.9 9.3 8.2 7.9 3.6 8.6 17.1 9.4 8.4 11.9 16.6 9.0 24.1 10.2 19.8 13.4 9.0 11.9 20.9 13.4 12.7 14.7 19.7 15.9 13.4 8.5 12.6 8.8 23.7 11.6 8.9 31.0 33.9 15.5 29.3 29.1 28.4 35.7 18.2 28.1 22.7 14.9 13.2 27.4 34.8 18.2 14.8 159.9 25.5 25.4 21.6 17.4 9.8 12.0 53.0 19.2 60.2 23.2 19.1 23.3 33.4 5.0 14.9 30.3 19.6 58.0 27.9 27.0 29.4 26.4 35.8 48.4 12.4 30.9 21.9 21.6 25.3 53.2 29.4 17.5 29.0 36.5 28.8 51.8 26.4 19.2 9.7 18.6 8.6 17.0 18.0 35.7 ADA ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease mutation, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 64.0;intestine: 142.2;lymphoid tissue: 99.0" "Cell type enhanced" "Detected in many" 10 "Extravillous trophoblasts: 90.2;Leydig cells: 39.1;monocytes: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 64.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "JURKAT: 61.5;MOLT-4: 198.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" No No 650000 "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (6.77e-5)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 8.1 3.2 2.5 5.4 6.5 5.3 5.1 0.9 5.0 2.8 7.4 5.0 1.8 142.2 1.7 3.4 4.6 2.4 3.0 9.2 2.7 0.8 1.3 2.1 2.8 8.9 3.6 2.3 1.2 2.4 0.8 0.3 1.8 3.9 1.8 1.5 0.7 2.6 1.3 2.0 2.8 5.0 2.1 1.3 9.5 19.7 1.6 6.1 99.0 2.8 2.1 7.6 3.6 2.6 1.3 41.6 0.5 64.0 16.9 10.3 9.6 1.4 4.0 2.0 1.4 3.9 5.5 3.3 1.4 0.8 1.4 1.0 1.8 1.5 4.0 1.7 1.9 2.7 0.2 1.4 5.9 0.8 0.3 1.8 0.8 0.7 1.4 1.6 0.6 2.2 26.2 2.5 0.5 0.9 1.3 5.4 61.5 2.0 3.3 0.6 3.4 198.0 2.9 0.5 1.8 1.4 10.7 2.8 9.9 0.2 0.0 0.0 0.9 2.1 0.4 2.5 2.7 0.4 1.9 1.7 1.0 2.0 2.2 0.2 4.3 2.7 8.3 0.3 3.3 0.9 0.0 1.8 0.2 8.7 30.7 5.7 1.3 7.3 10.3 6.8 1.0 5.7 8.1 0.5 16.9 64.0 41.6 5.3 9.6 2.5 6.5 0.9 5.0 2.7 0.8 3.6 2.3 3.9 6.1 0.0 3.4 12.7 3.0 11.4 0.0 1.9 0.0 2.7 0.0 1.8 0.0 2.3 0.0 3.7 0.1 16.2 0.5 0.0 17.9 90.2 16.7 0.9 0.0 2.9 27.6 0.0 0.0 6.7 13.4 1.5 39.1 14.4 8.5 49.5 1.4 2.9 8.2 0.0 2.5 2.1 0.0 12.9 16.1 0.4 1.3 12.2 3.1 30.5 3.3 2.4 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17221989 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.0" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 22.1;Ciliated cells: 28.1;Club cells: 20.5;Hofbauer cells: 58.5;Macrophages: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.2;EFO-21: 11.6;HUVEC TERT2: 12.5;Karpas-707: 22.3;MOLT-4: 20.7;U-266/70: 12.8;U-937: 21.0" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 50000000 "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 24.7 6.6 6.9 15.3 7.5 8.7 6.3 9.7 9.2 7.8 9.8 17.3 3.9 7.0 9.6 7.0 6.9 18.2 12.4 15.9 6.4 8.8 15.2 8.5 28.6 24.3 9.2 5.8 8.9 6.7 0.6 13.7 8.4 14.5 7.4 12.3 15.3 6.9 6.3 2.5 2.5 12.6 7.9 18.2 45.0 7.2 9.7 5.3 63.0 7.5 2.9 22.6 18.0 4.1 6.1 29.8 2.6 46.4 9.5 7.9 28.3 0.0 0.0 3.4 0.0 0.0 0.6 0.1 1.2 0.2 0.0 0.0 0.0 13.2 3.0 11.6 3.6 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.2 0.1 6.3 0.0 0.1 0.0 0.0 12.5 4.4 0.1 22.3 0.5 0.0 20.7 1.5 10.3 0.0 0.0 0.4 0.0 3.2 0.0 3.9 5.9 0.1 0.0 0.1 0.0 10.6 0.0 5.9 1.4 0.0 0.1 0.1 0.0 12.8 1.1 0.7 0.1 21.0 0.1 2.6 44.1 2.4 7.9 46.4 6.3 6.1 6.4 7.9 29.8 5.0 7.6 7.8 2.1 9.5 35.2 14.7 3.6 28.3 6.9 7.5 9.7 9.2 6.4 8.8 9.2 5.8 14.5 5.3 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 28.1 20.5 5.2 0.0 0.4 6.6 2.3 0.0 0.0 0.0 0.0 4.6 0.6 0.0 0.0 4.7 0.0 58.5 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 1.8 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 ADAM10 "CD156c, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588807-58749978 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 77.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 8200000 "Plasma membrane" "Nucleoplasm, Vesicles" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 25.9 11.1 15.5 17.1 17.7 15.6 20.0 25.2 17.6 18.6 20.1 15.7 12.7 13.9 19.9 11.8 17.1 13.8 18.0 18.8 17.6 13.7 20.8 14.8 25.0 26.1 23.1 12.4 13.9 13.1 10.9 11.6 36.1 14.5 23.6 16.7 14.6 12.4 19.1 8.9 15.4 15.6 12.8 30.4 40.4 18.4 8.5 18.9 38.5 27.3 9.2 14.9 30.0 19.1 6.2 12.7 26.9 23.7 9.8 12.2 12.8 12.1 27.4 7.5 8.1 9.6 13.9 18.9 10.4 31.0 7.7 10.7 12.6 16.1 5.6 32.2 9.3 13.5 24.8 4.5 11.0 10.2 8.4 5.8 9.6 10.0 11.7 10.7 6.8 27.7 12.1 8.1 5.4 7.9 11.2 14.9 12.2 6.0 15.3 13.5 4.5 22.4 7.7 10.2 4.0 3.9 9.3 24.5 14.4 17.9 32.7 8.1 5.3 11.3 13.2 18.0 17.1 7.8 13.6 10.5 10.1 11.3 77.5 10.0 8.6 18.5 6.1 14.1 13.1 17.6 12.9 18.8 10.4 8.1 21.5 12.2 5.3 8.0 7.1 12.7 6.2 8.4 7.0 26.9 9.8 23.7 5.8 10.3 12.8 15.5 17.7 25.2 16.9 17.6 13.7 23.1 12.4 14.5 18.9 77.4 49.8 30.6 25.8 23.7 20.2 29.7 30.6 30.8 35.2 76.8 25.5 27.4 1.7 45.7 21.6 61.6 39.3 0.0 27.7 46.7 28.8 75.5 27.9 30.4 56.9 42.9 34.7 76.1 87.0 16.2 16.7 64.0 43.9 13.6 45.8 27.0 37.3 43.2 15.9 20.3 32.7 12.9 28.3 13.6 16.2 19.4 22.2 43.6 33.7 59.6 ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9555792 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, HPA051575" Approved Supported Cytosol "Intracellular and membrane" NA NA 27000 Cytosol "HPA010738: AB_1078100, HPA051575: AB_2681539" "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (4.23e-5)" 18.6 11.0 13.6 15.4 13.8 21.9 14.7 20.4 15.5 14.0 11.7 13.8 8.3 8.7 14.2 15.8 18.7 10.7 17.4 13.4 11.2 12.4 12.4 7.8 24.7 15.0 11.6 11.7 18.1 9.6 10.9 11.9 29.0 11.2 8.2 9.4 10.6 12.5 9.8 12.3 16.7 11.1 13.9 14.3 21.4 8.9 17.4 12.3 14.7 12.5 13.9 20.3 12.3 14.4 7.0 7.7 16.0 10.2 6.0 7.9 6.0 7.7 12.7 13.4 13.9 26.4 19.7 24.1 8.1 13.8 9.3 13.9 11.2 18.6 22.0 11.7 10.1 27.3 14.1 9.8 17.2 12.8 8.8 9.8 11.2 9.6 9.9 37.3 11.0 12.6 22.0 17.3 14.9 29.0 20.8 23.4 8.4 15.3 8.5 10.0 7.3 8.2 11.0 11.0 10.8 5.1 9.6 13.1 10.4 12.4 12.8 7.9 19.7 9.0 11.0 19.2 15.1 5.7 14.2 18.7 16.6 8.7 11.6 15.4 11.1 9.9 19.2 13.8 7.1 19.7 16.0 9.8 7.6 6.1 10.2 7.9 7.0 5.0 5.1 7.7 5.1 4.5 4.6 11.8 6.0 9.5 4.3 5.7 6.0 13.6 13.8 20.4 13.1 11.2 12.4 11.6 11.7 11.2 12.3 44.7 76.6 33.0 41.9 115.4 24.9 2.8 12.7 25.4 40.9 29.6 51.1 25.3 5.0 20.9 64.8 44.9 15.5 23.3 16.8 39.0 58.0 41.4 29.0 11.0 32.9 9.5 18.9 42.4 70.5 10.4 17.5 74.4 38.8 26.2 13.4 12.3 18.2 17.3 15.2 7.5 38.2 38.8 26.7 25.4 37.8 135.3 46.8 26.2 12.5 92.9 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 53.7" "Cell type enhanced" "Detected in many" 12 "Cholangiocytes: 7.6;Early spermatids: 20.6;Ito cells: 8.0;Late spermatids: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4 "basophil: 2.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.3" "Cell line enhanced" "Detected in many" "SuSa: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 38000000 Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 1.4 1.0 3.1 1.4 3.7 0.5 1.4 6.6 4.2 1.4 1.4 1.4 1.4 4.1 1.6 4.0 1.4 2.1 1.5 1.7 3.4 2.2 1.8 53.7 4.8 1.4 2.1 1.4 2.3 1.8 2.2 4.2 1.7 1.6 1.6 1.1 1.6 2.5 2.0 2.6 2.9 4.4 1.4 2.0 1.4 5.5 3.8 1.4 1.4 1.7 1.4 1.4 1.7 1.4 0.3 0.0 2.3 0.0 0.0 0.5 0.1 0.0 1.3 3.3 4.6 2.7 2.4 1.2 1.1 0.9 0.4 0.6 0.5 3.6 0.4 1.5 0.8 1.1 0.6 0.3 0.6 0.1 1.9 3.0 0.4 1.3 0.7 1.9 0.1 1.1 6.4 1.6 0.5 1.2 2.2 0.3 2.3 0.1 1.4 0.5 5.5 0.1 1.5 3.5 1.9 2.0 0.4 0.4 1.6 1.5 1.4 2.1 6.8 2.3 1.3 1.8 7.1 5.8 0.6 0.8 2.4 1.4 1.6 0.0 2.5 0.6 0.5 2.0 0.4 2.8 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.1 3.7 6.6 4.2 3.4 2.2 2.1 1.4 1.6 1.4 0.0 1.3 0.0 0.1 0.2 1.4 3.6 7.6 0.0 3.4 0.0 0.0 0.1 1.7 0.6 20.6 0.3 1.0 0.0 0.3 0.2 0.8 0.4 0.0 1.5 0.2 3.2 1.2 8.0 0.0 10.2 0.9 0.0 0.0 0.0 1.3 1.9 0.3 1.4 1.4 0.7 1.7 0.0 0.4 4.7 3.8 0.4 0.1 0.0 0.6 0.3 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110851-179345430 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 16 "Ito cells: 28.8;Kupffer cells: 58.6;Sertoli cells: 25.8;Smooth muscle cells: 16.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 14.0;ASC TERT1: 14.0;BJ: 12.3;fHDF/TERT166: 14.5;HHSteC: 45.5;HSkMC: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 24.2 4.3 0.9 5.8 0.7 0.7 29.1 0.9 2.3 16.3 10.1 0.4 3.9 2.7 12.0 9.5 6.0 7.2 9.5 10.1 0.7 1.2 4.2 7.4 13.1 25.9 1.0 1.3 6.3 2.7 1.0 8.7 15.1 2.4 6.0 2.6 3.8 2.5 3.8 3.8 4.6 4.6 13.8 0.7 16.5 4.2 4.3 0.5 0.8 3.2 5.9 1.2 8.8 14.7 1.4 1.3 2.1 0.3 0.8 0.6 0.1 0.0 0.0 0.0 0.3 14.0 14.0 0.0 12.3 2.1 4.7 5.0 0.0 0.0 0.0 0.1 14.5 0.3 0.0 0.7 0.0 2.0 0.0 0.7 0.0 0.0 0.9 45.5 0.0 0.0 36.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.5 0.0 0.0 0.1 0.8 0.0 4.0 0.0 7.9 1.2 10.3 0.0 0.1 0.0 0.0 0.3 0.1 0.0 1.5 0.3 0.4 0.6 0.2 0.3 0.6 0.5 0.4 1.3 1.4 0.5 0.5 2.1 0.8 0.1 0.8 0.5 0.1 0.9 0.7 0.9 2.3 0.7 1.2 1.0 1.3 2.4 0.5 0.0 0.6 0.0 0.3 1.9 0.0 1.2 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 1.4 0.0 0.0 0.0 0.1 13.5 0.2 1.1 0.5 3.9 0.0 0.0 28.8 58.6 2.1 4.6 2.9 0.0 0.0 0.0 0.0 0.8 0.0 12.0 0.0 0.0 25.8 16.1 0.5 2.6 2.4 0.0 0.0 0.0 0.1 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184308-161199056 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.0" "Cell type enriched" "Detected in many" 7 "Smooth muscle cells: 356.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basal ganglia: 20.7;cerebral cortex: 10.0;midbrain: 28.6;pons and medulla: 20.5;thalamus: 15.7" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 8.0" "Lineage enriched" "Detected in many" 8 "dendritic cells: 8.0" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 10.9;HUVEC TERT2: 13.2;SH-SY5Y: 7.4;TIME: 11.1;U-138 MG: 6.9;U-251 MG: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 58.0 9.7 2.6 18.1 20.7 1.8 14.6 1.5 10.7 7.8 6.3 33.4 0.0 1.9 5.8 2.0 7.7 14.2 16.4 19.5 3.4 2.3 3.1 11.0 15.7 2.7 28.6 3.5 35.7 10.6 4.7 4.9 4.4 20.5 5.8 3.4 0.0 1.7 1.7 7.7 1.7 3.0 12.0 15.5 1.9 8.1 1.7 15.7 0.0 7.5 1.2 1.4 8.7 4.0 0.5 8.0 1.0 0.2 0.4 0.6 0.2 0.0 0.0 0.2 0.1 6.1 3.9 0.6 4.9 0.2 0.4 2.8 0.2 0.1 0.2 4.1 1.5 0.0 0.1 0.0 0.0 1.7 0.1 0.3 0.1 0.4 1.2 0.6 0.0 0.1 4.3 0.0 10.9 0.1 0.0 13.2 0.1 0.1 0.3 0.3 0.1 0.0 0.2 4.9 0.0 0.0 0.1 4.8 0.1 0.0 0.1 0.1 7.4 0.0 0.1 0.1 0.3 0.2 0.5 11.1 6.9 0.1 0.3 9.8 0.2 0.1 0.1 2.1 0.1 0.1 0.7 0.2 0.2 0.6 0.1 0.3 0.3 0.3 0.3 0.1 0.5 0.4 0.4 1.0 0.4 0.1 8.0 0.3 0.2 2.6 20.7 1.5 10.0 3.4 2.3 28.6 3.5 20.5 15.7 0.0 5.5 0.0 2.3 27.7 2.2 2.8 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.3 0.0 43.0 0.0 0.0 0.0 0.2 33.3 8.7 0.0 0.8 0.8 3.2 0.0 48.5 1.5 0.0 0.3 6.0 33.7 1.8 0.0 0.3 0.0 0.0 1.1 0.0 1.0 51.8 356.4 2.3 0.6 16.7 0.3 1.5 0.0 4.4 ADAR "ADAR1, G1P1, IFI4" ENSG00000160710 "Adenosine deaminase, RNA specific" P55265 1 154582062-154627999 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing, RNA-mediated gene silencing" "DNA-binding, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003890, HPA051519, CAB056157" Enhanced Enhanced Nucleoplasm,Nucleoli No No Nucleoli Nucleoplasm "CAB056157: AB_2665578, HPA003890: AB_1078103, HPA051519: AB_2681520" "unprognostic (3.46e-1)" "unprognostic (8.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.83e-2)" "unprognostic (2.38e-1)" "unprognostic (9.37e-2)" "unprognostic (2.07e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (2.90e-1)" "unprognostic (4.13e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.30e-5)" "unprognostic (3.44e-1)" "unprognostic (1.49e-1)" "unprognostic (9.00e-2)" "unprognostic (3.94e-2)" 36.1 33.1 30.3 36.6 44.4 43.1 29.7 41.4 50.8 30.7 28.2 33.3 19.9 31.4 38.0 26.5 27.7 32.9 28.9 24.0 25.7 38.1 31.5 36.0 34.7 41.3 27.3 32.6 39.2 29.5 46.2 38.4 33.9 39.8 28.8 31.1 32.2 36.7 30.2 14.0 27.0 40.6 36.3 24.4 47.7 29.1 21.9 26.9 57.6 32.8 16.7 41.9 29.7 27.6 7.8 6.1 25.1 8.6 6.4 9.7 5.6 26.6 30.9 26.5 32.6 26.8 27.8 31.5 18.4 36.9 61.6 53.5 26.6 26.2 48.0 29.7 29.3 34.2 25.9 33.8 34.9 31.4 46.6 16.9 25.0 21.9 15.0 29.2 35.3 27.8 27.0 25.5 31.5 32.3 25.2 31.5 34.7 23.6 37.0 21.5 32.5 42.6 18.2 43.7 35.7 23.3 40.8 21.8 38.6 21.1 29.7 26.4 31.5 31.7 51.3 37.6 41.3 34.5 43.5 28.7 22.1 21.8 18.2 21.2 43.8 48.0 51.6 21.5 23.3 24.9 6.9 6.6 12.0 9.4 8.3 8.8 7.8 9.4 9.7 6.1 6.2 8.8 8.6 25.1 6.4 8.6 5.5 7.1 5.6 30.3 44.4 41.4 50.8 25.7 38.1 27.3 32.6 39.8 26.9 77.4 46.4 72.2 33.2 29.7 90.3 15.5 33.1 41.5 43.3 45.4 90.3 33.7 8.3 43.8 3.6 83.1 68.1 23.3 58.0 42.0 39.5 47.9 61.1 78.8 46.9 158.9 60.6 78.0 80.2 9.5 68.1 57.4 18.6 68.5 54.5 46.8 58.0 53.7 55.5 36.0 81.7 51.8 36.9 11.7 23.2 35.3 26.3 58.3 48.2 41.3 ADARB1 "ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1" ENSG00000197381 "Adenosine deaminase, RNA specific B1" P78563 21 45073853-45226560 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 59.9" "Cell type enhanced" "Detected in many" 9 "Bipolar cells: 52.9;Horizontal cells: 65.2;Muller glia cells: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 27.9;HHSteC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029645 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA029645: AB_10602106" "unprognostic (2.69e-1)" "unprognostic (7.65e-2)" "prognostic unfavorable (8.16e-5)" "unprognostic (1.82e-2)" "unprognostic (1.07e-2)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (6.97e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.57e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-2)" "unprognostic (2.38e-2)" 12.2 5.3 7.1 10.4 8.4 4.5 8.9 33.1 11.6 11.7 17.2 2.5 5.6 2.9 13.4 6.6 14.0 8.8 11.1 6.7 7.3 8.1 4.6 4.0 19.9 11.8 7.4 8.1 5.3 4.7 19.0 3.7 12.0 13.6 14.7 5.0 11.0 4.6 8.7 11.8 10.8 5.9 59.9 3.5 10.5 11.7 3.8 4.0 3.9 3.8 4.5 8.4 34.6 20.3 6.1 2.1 4.8 0.6 0.5 2.6 0.5 3.1 0.4 2.5 2.9 3.1 2.1 3.4 2.1 3.5 6.9 4.4 5.0 0.5 1.0 5.8 10.5 3.8 0.3 3.7 8.9 7.6 0.7 3.3 6.9 27.9 3.3 32.3 4.7 3.4 11.6 3.9 2.4 7.2 2.6 7.2 9.6 1.6 0.4 20.0 2.3 3.1 4.5 4.0 1.6 4.8 0.9 2.4 3.2 1.5 1.0 14.7 3.9 17.1 0.7 5.4 4.3 1.6 3.8 7.6 2.3 2.8 9.2 8.0 3.1 1.4 0.8 2.0 11.1 12.1 1.3 0.2 4.8 1.1 0.6 1.8 2.4 2.6 1.6 0.0 6.1 1.8 1.4 0.2 0.5 0.3 2.1 1.6 0.5 7.1 8.4 33.1 11.6 7.3 8.1 7.4 8.1 13.6 4.0 0.0 0.6 3.2 2.5 9.8 52.9 17.1 0.0 0.0 2.3 0.0 11.8 0.4 0.0 1.3 2.0 13.5 0.4 0.0 0.4 0.9 11.0 4.9 8.1 5.9 6.1 65.2 0.0 14.7 3.4 1.9 3.4 2.9 5.0 7.2 0.7 34.4 1.0 0.0 5.3 2.2 15.5 0.0 18.6 4.1 11.5 6.4 0.8 6.9 1.2 2.0 ADAT1 ENSG00000065457 "Adenosine deaminase, tRNA specific 1" Q9BUB4 16 75596981-75623300 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 80.3;Late spermatids: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040713, HPA040903" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA040713: AB_10795371, HPA040903: AB_10794071" "unprognostic (7.71e-3)" "unprognostic (5.35e-2)" "unprognostic (7.62e-2)" "unprognostic (9.00e-2)" "unprognostic (9.99e-2)" "unprognostic (4.69e-2)" "unprognostic (4.54e-2)" "unprognostic (6.65e-3)" "unprognostic (3.38e-1)" "unprognostic (1.14e-2)" "unprognostic (9.75e-2)" "unprognostic (2.97e-1)" "unprognostic (4.60e-3)" "unprognostic (7.21e-2)" "unprognostic (4.92e-1)" "unprognostic (5.58e-3)" "unprognostic (8.27e-2)" 14.8 17.1 12.5 12.6 18.2 13.0 15.1 11.0 23.3 13.5 12.4 21.4 11.8 10.1 15.1 24.4 12.0 12.6 15.8 10.4 17.2 15.1 17.2 17.8 12.8 21.2 16.7 20.5 11.1 15.3 33.5 16.7 14.0 22.3 15.3 15.1 11.8 12.2 14.2 9.0 21.2 13.6 12.6 16.0 21.3 11.7 51.8 16.8 19.4 20.6 9.2 16.7 17.1 11.3 12.5 8.6 15.0 13.0 12.1 20.5 8.3 14.1 23.2 14.0 14.5 21.1 17.3 13.1 15.7 18.0 21.4 17.1 19.2 21.7 16.8 16.7 14.2 12.1 16.1 12.9 20.2 21.3 11.0 7.6 7.4 16.1 13.5 15.5 14.3 16.7 19.1 15.9 31.8 26.0 6.7 17.9 20.7 12.4 7.6 18.8 53.0 16.6 13.5 11.5 14.5 10.0 19.7 12.0 20.8 20.9 21.8 19.8 20.5 35.5 11.1 9.7 12.9 23.0 9.5 13.0 34.4 14.2 13.8 15.0 16.1 22.6 46.9 14.9 15.3 28.4 9.6 7.2 15.0 14.7 8.4 20.5 12.5 13.8 20.0 8.0 11.8 8.5 12.0 9.5 12.1 13.0 8.6 14.0 8.3 12.5 18.2 11.0 23.3 17.2 15.1 16.7 20.5 22.3 16.8 8.9 4.3 7.6 4.6 4.0 13.4 4.8 5.1 9.4 4.5 7.0 25.5 11.0 14.9 7.4 80.3 8.5 5.9 23.3 6.7 7.7 5.4 7.1 8.1 8.7 8.8 12.7 13.8 6.7 10.4 160.0 9.2 10.2 3.3 10.8 5.3 7.2 8.0 3.5 7.4 8.6 18.9 6.5 5.7 14.0 11.7 4.6 8.1 9.6 8.0 6.5 ADAT2 "DEADC1, dJ20N2.1, TAD2" ENSG00000189007 "Adenosine deaminase, tRNA specific 2" Q7Z6V5 6 143422832-143450673 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035479 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA035479: AB_10611672" "unprognostic (2.24e-1)" "unprognostic (3.07e-3)" "unprognostic (1.55e-1)" "unprognostic (8.20e-2)" "unprognostic (3.05e-2)" "unprognostic (8.58e-2)" "unprognostic (1.07e-3)" "unprognostic (3.31e-2)" "unprognostic (1.34e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-2)" "unprognostic (9.28e-5)" "unprognostic (4.88e-2)" "unprognostic (6.96e-2)" "unprognostic (7.29e-2)" "unprognostic (4.08e-2)" 7.3 9.5 6.6 15.1 9.4 17.1 8.6 7.7 8.8 6.6 9.5 4.9 4.7 9.9 8.3 5.3 12.0 7.9 7.6 4.2 5.2 3.8 7.5 13.2 11.3 17.6 4.9 8.0 7.5 13.3 7.1 9.6 4.0 7.3 8.6 13.3 6.0 10.1 6.2 13.3 17.1 10.0 6.5 6.7 13.1 10.8 4.1 5.3 8.6 10.8 10.1 13.5 6.6 8.7 2.8 3.2 0.4 1.4 1.9 6.6 2.3 2.9 2.5 3.1 10.6 2.6 8.5 4.7 4.2 1.9 2.9 4.1 6.7 7.5 10.5 4.6 2.8 3.3 8.6 5.8 5.9 5.7 5.5 13.0 14.8 10.5 13.5 3.3 20.8 7.4 2.9 8.7 5.7 9.1 2.5 6.2 9.7 16.1 9.1 4.4 4.2 8.0 11.7 4.0 4.0 4.8 9.8 9.2 8.5 4.5 3.3 6.9 4.7 3.5 9.5 2.8 1.7 4.0 7.6 4.8 4.3 3.6 8.8 8.0 9.4 6.6 7.9 4.0 17.5 4.9 0.0 0.9 0.0 3.2 1.4 4.7 2.8 3.0 2.9 3.2 2.0 3.4 5.1 0.4 1.9 0.2 3.0 6.6 2.3 6.6 9.4 7.7 8.8 5.2 3.8 4.9 8.0 7.3 5.3 6.0 11.7 0.8 3.4 6.0 3.6 2.7 0.0 2.7 4.5 1.8 0.0 2.0 3.3 3.4 1.0 4.7 1.8 23.3 3.4 2.1 4.4 2.9 7.0 4.0 4.1 1.6 4.1 4.3 5.1 1.1 6.4 2.8 5.0 0.0 5.6 2.0 4.8 0.0 3.2 0.7 3.1 0.0 4.9 1.8 5.4 8.2 0.7 6.9 7.8 3.8 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 16.0;HEL: 11.5;HMC-1: 13.0;Karpas-707: 17.6;U-266/70: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Nuclear membrane" Nucleoplasm "CAB001701: , HPA036961: AB_2675405" "prognostic favorable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 14.3 8.5 2.3 10.9 4.6 2.5 14.8 1.2 2.4 7.1 6.2 4.7 14.6 1.9 7.9 6.2 5.0 5.4 6.6 8.4 2.3 2.4 5.1 5.5 17.4 18.9 3.7 2.7 3.6 11.9 8.1 2.8 23.0 4.0 6.3 3.9 6.8 6.5 14.5 19.7 3.1 6.4 8.8 4.7 13.6 5.1 4.1 3.6 5.3 7.4 5.8 12.0 7.1 6.9 8.2 8.0 13.3 13.0 3.4 9.6 4.9 1.6 2.0 0.5 0.0 1.7 1.9 0.0 1.4 0.3 1.2 1.6 0.6 1.3 0.4 0.6 2.1 0.0 0.1 1.4 0.0 1.2 16.0 0.1 11.5 0.2 0.0 2.8 0.0 13.0 2.8 0.0 0.6 0.0 0.5 5.0 0.0 1.0 17.6 7.6 0.5 0.0 2.7 4.8 0.1 4.0 0.0 5.7 0.7 0.7 0.6 0.3 0.0 0.0 0.1 4.3 0.7 3.1 7.2 4.1 0.0 0.8 3.2 0.3 17.2 3.8 0.0 2.1 0.0 3.1 7.8 13.0 13.3 0.6 12.0 0.6 8.2 1.4 1.3 8.0 4.9 0.2 0.6 0.4 3.4 9.2 7.0 9.6 4.9 2.3 4.6 1.2 2.4 2.3 2.4 3.7 2.7 4.0 3.6 8.9 7.5 4.5 0.7 0.7 0.6 4.1 2.5 2.7 4.5 3.5 3.9 4.8 1.7 2.2 0.8 8.4 0.0 0.0 2.9 3.2 1.1 0.9 10.4 1.3 8.4 0.0 0.0 5.5 9.4 0.4 0.3 10.6 1.7 7.2 0.1 0.8 2.4 0.0 2.8 0.8 4.6 0.0 2.9 0.5 0.2 0.6 9.8 1.3 0.0 0.1 ADPRHL2 "ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylhydrolase like 2" Q9NX46 1 36088875-36093932 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 15.5 27.6 17.4 15.2 17.4 16.9 20.0 16.5 22.7 15.9 17.3 30.3 17.7 15.6 14.3 17.8 26.3 28.4 13.5 15.1 19.1 18.9 19.8 16.5 20.7 19.1 25.8 18.5 19.7 27.6 15.1 14.0 20.9 19.7 16.6 12.9 12.2 21.9 20.2 26.4 24.4 17.7 22.2 23.5 18.0 14.1 25.1 20.0 21.2 21.2 22.3 19.7 16.1 15.9 27.7 38.9 34.1 38.8 23.5 29.3 29.2 25.7 10.9 13.0 18.3 12.0 8.8 18.6 19.2 16.2 31.1 30.7 12.9 23.4 18.4 18.8 19.1 16.1 16.1 16.4 29.5 18.7 13.1 20.6 16.7 13.2 17.3 22.7 19.0 9.9 10.3 22.6 28.1 12.3 23.7 19.6 17.8 14.4 15.3 14.5 12.4 19.2 28.8 28.0 15.3 22.7 15.7 13.7 18.5 27.8 21.2 16.0 25.4 14.1 14.8 31.3 18.0 15.2 16.5 13.4 18.0 18.6 24.9 25.4 19.9 19.0 16.3 26.0 18.9 11.0 18.2 32.4 34.1 25.5 38.7 24.0 23.6 27.9 29.3 38.9 27.7 28.3 24.0 31.4 23.5 38.8 24.6 22.8 29.2 17.4 17.4 16.5 22.7 19.1 18.9 25.8 18.5 19.7 20.0 29.8 10.0 22.9 24.4 34.9 17.7 7.3 15.3 30.8 14.8 21.0 5.9 67.9 29.9 47.4 6.6 17.1 20.1 0.0 30.7 33.5 19.7 18.0 14.9 6.0 46.0 9.5 16.7 11.1 11.2 7.9 15.3 22.0 25.3 45.1 12.5 24.3 38.3 15.0 17.0 36.1 15.8 25.8 17.9 24.4 46.2 35.8 59.0 19.2 19.8 22.7 ADPRM "C17orf48, MDS006" ENSG00000170222 "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" Q3LIE5 17 10697594-10711233 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023265, HPA023820" Approved NA NA "HPA023265: AB_1845590, HPA023820: AB_1845591" "unprognostic (7.58e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.42e-1)" "prognostic favorable (2.38e-5)" "unprognostic (2.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.43e-1)" "unprognostic (6.26e-3)" "unprognostic (2.97e-1)" "unprognostic (6.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (4.77e-2)" "unprognostic (5.97e-2)" 11.1 8.2 6.4 9.3 13.1 12.9 13.0 9.8 12.2 10.3 8.1 10.1 16.1 6.6 11.3 9.1 7.8 9.0 7.9 6.4 9.6 6.1 7.8 15.2 6.9 23.2 8.1 5.6 14.2 12.4 4.2 11.9 4.9 9.3 16.7 7.5 8.3 8.8 13.4 14.8 9.2 9.9 6.5 7.3 10.5 12.2 9.5 8.2 18.8 14.6 10.4 11.1 8.8 9.0 10.5 4.2 6.1 3.5 4.0 18.7 5.9 4.1 2.2 4.5 5.3 10.5 13.6 2.3 7.9 8.8 5.8 8.7 1.4 2.0 8.1 4.3 8.3 3.0 3.4 1.9 5.7 6.9 5.1 5.3 5.9 3.7 4.5 18.8 3.0 5.5 15.6 10.4 6.1 9.0 10.7 10.1 8.3 4.0 1.5 8.3 1.1 3.9 5.4 3.7 3.0 2.1 3.4 5.3 2.4 10.1 3.1 1.0 6.4 4.2 1.6 9.8 4.9 3.8 6.0 10.3 4.0 2.4 4.5 5.2 2.0 1.4 2.4 7.9 4.5 6.7 3.4 3.5 6.1 3.2 3.0 5.4 8.2 8.8 5.8 4.2 10.5 18.7 12.0 2.5 4.0 3.1 2.4 7.7 5.9 6.4 13.1 9.8 12.2 9.6 6.1 8.1 5.6 9.3 8.2 3.0 1.3 31.2 12.3 4.6 10.4 2.2 2.5 2.7 5.7 1.8 17.7 6.0 3.3 7.7 6.0 6.0 5.1 0.0 7.3 5.7 5.4 10.1 13.9 7.8 5.8 3.2 4.6 4.3 5.1 4.1 14.7 7.9 10.1 10.8 7.4 13.2 7.7 3.5 7.8 6.1 33.4 6.5 10.3 9.2 9.2 4.1 6.9 10.0 4.7 8.9 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.7" "Cell type enhanced" "Detected in many" 6 "Cholangiocytes: 68.8;Hepatocytes: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 14.5" "Group enriched" "Detected in all" 5 "B-cells: 5.1;dendritic cells: 6.7;monocytes: 14.5" "Cell line enhanced" "Detected in all" "Hep G2: 62.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 5.9 3.5 12.1 5.4 17.1 4.6 33.0 27.1 18.3 6.1 7.5 44.8 11.7 8.5 7.5 7.0 7.7 11.3 11.4 9.4 17.3 12.0 39.4 78.7 10.6 5.2 29.7 13.3 15.9 27.7 6.9 4.1 12.4 18.1 10.7 9.2 5.8 24.7 11.8 7.9 15.5 7.1 6.6 27.0 6.2 10.2 6.2 23.9 3.9 6.5 5.6 6.2 6.7 7.4 5.1 6.7 1.7 14.5 1.6 1.1 1.5 7.0 10.0 8.8 8.0 10.0 11.7 4.8 10.1 5.8 7.2 8.6 10.6 5.9 22.1 6.7 7.7 4.2 6.1 14.9 8.9 10.1 14.0 11.9 17.8 11.8 62.3 8.7 14.7 9.2 15.6 9.4 8.3 10.9 11.8 13.4 6.7 18.0 7.8 5.5 7.0 11.2 22.4 7.2 17.2 17.3 12.8 9.0 26.5 9.7 6.5 19.7 14.6 8.7 26.3 8.2 9.2 7.9 14.3 6.6 11.0 7.2 6.9 7.1 11.9 7.8 22.7 9.1 7.2 2.8 1.1 6.1 0.7 0.7 14.5 1.1 5.1 1.0 1.1 6.7 2.0 0.6 0.6 1.7 1.6 9.3 4.4 0.9 1.5 12.1 17.1 27.1 18.3 17.3 12.0 29.7 13.3 18.1 23.9 14.9 13.6 10.0 19.1 23.5 1.4 11.5 68.8 17.4 12.5 61.1 3.9 10.9 14.9 10.4 0.3 14.7 12.9 0.0 7.4 9.5 15.0 15.8 2.3 100.2 9.5 1.6 12.6 21.5 21.9 1.5 20.8 18.3 28.7 10.8 20.6 1.7 8.6 24.9 20.5 39.6 1.5 0.0 7.5 1.2 11.8 35.9 9.6 4.4 25.0 12.2 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430770-177442503 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 32.2;Karpas-707: 45.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" NA NA 28000000 "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (8.61e-4)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 12.8 15.1 11.2 11.2 11.9 10.9 18.5 4.4 13.7 13.5 12.1 24.2 8.0 8.0 9.8 26.4 18.8 7.1 15.1 8.4 13.0 9.4 20.5 26.5 12.4 12.3 14.0 11.0 10.2 14.7 19.2 9.0 9.3 15.0 10.1 11.1 24.0 27.1 10.8 6.7 16.9 14.4 8.1 22.3 14.9 13.0 13.3 10.0 13.4 14.0 14.3 18.3 9.0 10.2 10.0 11.1 16.3 23.8 8.9 16.3 10.3 2.1 4.7 5.4 7.7 6.4 5.7 3.7 15.8 32.2 8.2 10.4 2.5 10.6 10.5 2.9 12.2 4.0 2.6 4.6 5.2 16.7 6.8 3.0 4.4 5.2 6.9 4.2 7.6 3.0 4.0 9.1 6.0 2.7 7.4 7.7 4.7 3.9 45.6 3.3 5.8 6.1 4.8 2.1 4.2 4.9 1.9 2.2 1.6 8.7 5.3 3.0 6.9 4.7 4.1 12.5 4.3 9.3 15.7 2.4 5.7 5.1 2.7 6.1 8.8 6.7 5.6 9.2 8.7 6.4 15.0 10.7 16.3 11.7 18.9 13.4 10.0 12.8 14.0 10.5 8.1 11.4 16.3 2.4 8.9 23.8 11.1 12.0 10.3 11.2 11.9 4.4 13.7 13.0 9.4 14.0 11.0 15.0 10.0 11.9 9.1 12.3 14.9 21.3 3.3 5.7 17.8 5.3 11.4 14.0 2.0 21.6 5.0 21.9 11.4 11.1 9.1 0.0 27.5 25.3 15.5 15.7 13.9 15.1 21.7 6.4 5.2 6.2 9.1 6.8 10.3 22.8 37.1 25.2 16.6 17.6 20.6 5.8 9.2 16.3 3.7 0.0 12.4 34.8 31.5 23.8 19.0 22.3 13.4 15.2 AGL ENSG00000162688 "Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase" P35573 1 99850084-99924023 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycogen biosynthesis" "Glycosidase, Glycosyltransferase, Hydrolase, Multifunctional enzyme, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 23.1;skeletal muscle: 85.6;tongue: 34.4" "Cell type enhanced" "Detected in all" 6 "Muller glia cells: 151.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028498, HPA054340" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 16000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA028498: AB_10600975, HPA054340: AB_2682455" "unprognostic (2.90e-1)" "unprognostic (5.34e-2)" "unprognostic (3.99e-3)" "unprognostic (2.18e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "unprognostic (1.12e-1)" "unprognostic (1.92e-2)" "unprognostic (9.37e-3)" "unprognostic (1.11e-1)" "unprognostic (8.10e-3)" "unprognostic (7.61e-2)" "prognostic favorable (1.73e-10)" "unprognostic (6.38e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" "unprognostic (7.13e-2)" 5.0 4.5 2.5 4.7 3.6 2.0 4.2 5.4 6.1 3.4 4.5 2.1 5.4 3.3 4.8 4.2 9.1 4.1 2.6 8.2 2.2 2.3 5.8 23.1 4.2 5.3 2.4 4.2 3.8 3.6 8.7 4.7 4.8 2.9 5.5 4.2 3.9 5.1 8.7 85.6 3.7 4.0 5.4 2.8 4.8 4.4 2.9 1.2 7.1 4.3 34.4 3.4 6.7 3.6 3.0 2.3 3.5 1.6 6.1 4.3 2.1 12.1 3.6 4.3 7.0 7.1 6.8 14.5 3.8 5.7 3.4 6.0 13.5 4.1 15.9 7.4 6.5 3.0 6.9 25.1 7.5 6.4 8.4 7.9 9.2 12.4 7.5 4.7 8.2 5.6 8.2 4.9 4.7 3.9 4.8 5.3 5.6 15.2 1.1 3.5 3.8 9.6 2.6 6.8 5.4 4.6 0.0 1.4 0.8 10.3 16.4 10.7 7.4 11.1 10.7 6.0 8.4 7.7 5.5 5.4 4.1 5.9 5.5 3.7 4.5 3.6 18.4 7.2 2.2 2.1 0.1 1.3 3.5 4.3 1.6 4.1 3.0 3.2 2.9 2.3 2.9 3.2 3.2 1.5 6.1 0.9 2.1 3.3 2.1 2.5 3.6 5.4 6.1 2.2 2.3 2.4 4.2 2.9 1.2 20.8 23.2 15.3 15.5 9.4 36.9 94.9 20.4 29.4 29.6 15.7 51.1 77.6 19.9 11.9 1.1 10.8 15.8 23.3 11.2 17.2 13.6 9.9 10.4 84.7 15.8 49.3 16.1 16.0 16.2 1.1 9.5 9.2 15.1 10.8 18.2 151.6 14.2 10.5 20.1 16.3 47.8 6.5 14.2 8.1 11.7 8.2 24.4 15.0 17.4 16.6 AGMAT FLJ23384 ENSG00000116771 Agmatinase Q9BSE5 1 15572353-15585110 "Enzymes, Predicted intracellular proteins" "Putrescine biosynthesis, Spermidine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;kidney: 54.7;liver: 66.1" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 278.6" "Group enriched" "Detected in all" 5 "colorectal cancer: 18.5;liver cancer: 25.3;renal cancer: 11.2;stomach cancer: 11.1" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.6;T-cells: 10.5" "Cell line enhanced" "Detected in many" "CACO-2: 19.0;Hep G2: 46.0;RPMI-8226: 11.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA026443, HPA028321" Enhanced NA NA 250000 "HPA026443: AB_1844644, HPA028321: AB_10600779" "unprognostic (2.27e-2)" "unprognostic (3.45e-1)" "unprognostic (1.79e-3)" "unprognostic (3.60e-2)" "unprognostic (8.72e-2)" "unprognostic (6.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.13e-4)" "unprognostic (4.43e-3)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (2.45e-2)" 0.7 0.8 0.7 2.8 0.5 0.1 0.4 0.2 1.0 0.2 14.9 0.3 0.0 7.1 0.3 1.2 0.5 0.2 3.6 0.3 0.6 0.8 54.7 66.1 0.2 1.3 0.7 0.3 0.2 1.1 1.3 0.4 0.2 0.6 0.3 2.8 0.1 9.6 0.0 12.3 0.2 21.3 0.1 0.3 1.0 0.5 0.5 0.1 1.0 0.3 1.7 1.5 0.4 0.2 4.6 0.4 1.4 0.3 0.4 10.5 2.8 4.0 3.2 0.2 0.1 0.0 0.4 0.1 0.7 0.7 0.4 0.2 19.0 2.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.5 3.9 0.0 2.5 2.7 46.0 0.5 2.0 0.0 0.5 0.2 1.3 0.0 0.3 0.4 0.0 0.0 5.4 1.0 4.3 0.0 1.9 4.3 3.2 1.8 0.0 0.0 11.4 0.1 1.0 0.7 0.6 5.5 0.2 0.6 0.2 0.7 3.8 0.5 0.1 0.1 1.0 0.0 0.1 3.0 2.6 0.2 0.0 0.0 0.9 0.3 0.2 2.4 0.3 3.1 4.6 5.7 3.0 0.2 3.2 10.5 5.9 1.4 0.4 0.2 0.4 7.1 2.8 0.7 0.5 0.2 1.0 0.6 0.8 0.7 0.3 0.6 0.1 0.0 0.0 3.2 1.5 0.2 1.2 0.4 5.1 1.4 0.0 3.5 0.0 0.7 26.6 0.8 6.9 0.1 12.9 0.0 0.8 0.7 0.7 0.9 0.0 38.9 0.9 3.2 1.2 1.8 2.2 3.6 0.3 0.4 1.7 1.0 6.7 0.8 2.0 3.5 0.0 278.6 1.7 0.0 0.4 1.6 2.9 0.5 0.7 5.0 13.8 2.6 AGO2 "CASC7, EIF2C2, hAGO2, LINC00980, Q10" ENSG00000123908 "Argonaute 2, RISC catalytic component" Q9UKV8 8 140520156-140635619 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019309, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 35000000 "Cytoplasmic bodies" Cytosol "CAB019309: , HPA067849: " "unprognostic (2.75e-2)" "unprognostic (1.79e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.46e-1)" "unprognostic (2.15e-1)" "unprognostic (1.49e-3)" "unprognostic (8.86e-2)" "unprognostic (2.21e-1)" "unprognostic (8.50e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (1.32e-1)" "unprognostic (2.77e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-1)" 11.2 6.6 7.7 9.9 13.1 16.2 25.0 9.9 11.4 7.5 9.2 12.1 12.8 5.3 10.2 10.4 10.6 8.6 8.8 12.4 8.8 5.3 6.9 7.4 13.2 12.5 13.4 5.0 11.8 8.4 13.2 8.8 9.9 10.7 7.5 6.9 5.6 8.1 12.6 37.1 14.1 7.5 15.0 11.7 6.9 10.0 5.9 12.7 11.1 8.6 8.2 8.9 10.4 18.4 2.5 2.1 6.4 2.6 2.4 3.0 1.5 12.8 10.6 10.9 12.4 7.1 8.4 9.2 8.1 5.9 3.6 4.5 11.7 3.9 14.7 10.2 7.8 3.9 8.7 18.4 8.7 8.1 8.3 9.6 17.2 18.2 7.4 6.5 7.1 5.9 5.7 7.9 10.0 10.5 5.0 8.4 9.3 18.0 9.3 11.8 19.4 12.2 5.6 8.0 8.8 18.5 12.6 9.2 6.6 4.6 13.3 12.8 9.3 12.6 4.3 9.0 11.7 11.1 10.3 11.7 6.3 17.6 9.9 12.9 8.2 2.7 10.4 4.7 12.9 9.3 1.8 2.6 0.7 2.7 2.3 3.0 1.3 2.6 2.3 2.1 2.5 2.7 2.7 6.4 2.4 2.3 1.5 2.1 1.5 7.7 13.1 9.9 11.4 8.8 5.3 13.4 5.0 10.7 12.7 20.8 21.4 18.4 57.8 19.5 24.7 19.4 10.2 24.1 36.4 14.0 41.2 36.5 6.6 23.4 15.7 24.8 9.7 70.0 15.6 17.2 23.7 85.4 16.2 12.4 13.3 39.7 23.3 25.8 23.8 10.0 34.5 19.0 5.0 22.6 22.7 30.6 29.0 17.5 43.5 7.4 29.6 32.3 13.1 3.2 1.4 20.8 66.1 25.4 19.6 78.7 AHCY SAHH ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Proximal tubular cells: 192.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol NA NA 3900000 Cytosol "HPA041225: AB_2677371, HPA044675: AB_2679041" "unprognostic (3.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-2)" "unprognostic (7.74e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-3)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (2.61e-1)" "unprognostic (4.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" 15.3 18.6 11.7 15.4 15.0 17.0 24.3 6.3 16.4 25.1 30.0 14.7 18.4 24.6 20.2 23.9 43.4 26.6 22.4 26.0 12.0 12.8 52.2 99.8 19.1 18.1 16.0 10.6 39.1 72.0 15.7 15.0 44.5 13.2 26.9 20.2 14.4 32.4 18.3 48.2 14.8 20.4 18.8 15.7 17.9 22.2 33.3 13.4 25.0 52.8 31.0 29.2 18.2 20.5 9.1 24.1 2.3 26.0 4.6 7.4 11.4 37.4 49.1 20.8 36.7 24.3 26.2 23.9 15.4 22.1 34.3 27.3 132.5 32.4 58.3 27.5 19.7 22.2 43.0 48.9 86.4 22.1 7.7 29.7 70.3 24.4 85.2 26.2 32.8 23.1 54.2 39.4 21.3 34.3 18.4 23.4 21.7 34.2 14.8 18.2 39.6 42.8 31.0 26.7 48.0 47.9 32.2 53.0 41.0 30.7 26.6 36.1 24.0 30.7 36.5 51.0 17.2 54.8 30.6 14.8 29.9 31.9 15.1 29.0 22.1 32.3 35.1 22.0 20.3 15.9 2.3 13.7 0.4 4.1 26.0 6.7 9.1 6.0 5.3 21.1 7.8 6.6 7.4 1.1 4.6 16.5 24.1 6.7 11.4 11.7 15.0 6.3 16.4 12.0 12.8 16.0 10.6 13.2 13.4 38.7 21.0 33.5 72.2 32.5 11.9 44.7 25.5 17.4 29.6 26.2 0.0 93.3 49.7 60.3 58.3 23.6 33.8 0.0 70.9 130.4 41.1 68.4 20.7 56.7 103.0 11.1 20.2 16.5 33.2 135.4 39.4 28.0 25.3 26.2 64.7 41.2 59.2 24.6 38.2 192.2 10.2 12.9 38.1 20.7 47.5 34.5 76.9 18.5 111.0 66.8 AHCYL2 KIAA0828 ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225023-129430211 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 72.4" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 2: 75.8;Enterocytes: 114.1;Muller glia cells: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 8 "HDLM-2: 73.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053128 Uncertain Approved Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA053128: AB_2682050" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (8.52e-3)" "unprognostic (1.71e-3)" "unprognostic (7.44e-3)" "prognostic favorable (4.17e-4)" "unprognostic (8.85e-2)" "unprognostic (1.43e-1)" "unprognostic (3.35e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-1)" "unprognostic (6.79e-3)" "prognostic favorable (1.08e-7)" "unprognostic (4.70e-3)" "unprognostic (2.46e-1)" "unprognostic (7.21e-2)" "unprognostic (2.62e-1)" 4.3 6.6 12.8 5.9 20.3 1.5 4.3 7.2 16.9 7.1 61.8 13.3 5.1 23.1 6.1 3.3 5.7 4.4 22.7 3.4 16.5 9.6 11.9 3.4 26.1 4.2 10.7 14.9 5.7 5.8 9.1 12.8 5.1 19.8 5.0 72.4 24.3 15.0 3.3 20.7 9.8 15.0 5.3 11.4 2.9 16.5 8.1 9.6 4.6 24.1 4.0 4.0 5.4 4.7 0.9 1.3 2.0 2.5 3.3 5.0 0.5 2.7 4.3 8.3 4.9 2.2 3.3 1.7 2.1 3.0 2.4 2.2 2.5 1.8 1.6 2.2 2.3 5.2 1.9 4.1 3.4 2.7 73.5 5.1 3.9 4.8 2.0 1.3 2.8 5.0 3.0 4.4 1.9 3.0 4.1 4.8 3.2 1.7 9.3 3.1 2.5 4.2 3.7 4.1 2.7 3.0 2.8 2.2 4.4 4.9 3.6 3.8 2.4 4.9 2.1 2.9 7.2 2.0 2.1 2.7 2.1 1.2 5.5 2.2 3.9 4.4 2.2 5.4 3.1 3.2 0.1 1.2 2.0 0.9 2.5 1.2 0.9 1.5 0.7 1.3 0.5 1.3 0.5 0.4 3.3 1.2 0.4 5.0 0.5 12.8 20.3 7.2 16.9 16.5 9.6 10.7 14.9 19.8 9.6 56.6 75.8 3.4 4.5 13.9 9.4 4.5 17.8 5.3 19.4 5.2 5.9 8.4 10.0 3.6 61.0 3.9 114.1 0.0 4.9 2.2 3.1 6.2 5.7 4.9 3.9 4.8 8.7 4.3 8.3 20.3 3.7 5.1 23.6 7.2 29.7 87.7 4.5 30.8 6.3 15.7 5.0 6.5 1.2 4.6 2.4 8.5 12.7 3.2 32.7 13.9 AICDA "AID, ARP2, CDA2, HIGM2" ENSG00000111732 "Activation induced cytidine deaminase" Q9GZX7 12 8602166-8612871 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 6.6;lymphoid tissue: 22.3" "Cell type enhanced" "Detected in single" 10 "Alveolar cells type 2: 1.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 6.6" "Group enriched" "Detected in many" 6 "B-cells: 6.6;granulocytes: 1.6" "Group enriched" "Detected in some" 6 "Daudi: 49.6;U-698: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (2.71e-2)" "unprognostic (1.39e-2)" "unprognostic (7.76e-2)" "unprognostic (1.68e-1)" "unprognostic (8.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.05e-2)" "unprognostic (9.69e-2)" "unprognostic (1.96e-2)" "unprognostic (4.04e-6)" "unprognostic (8.82e-2)" "unprognostic (1.28e-1)" "unprognostic (4.21e-1)" "unprognostic (4.65e-1)" 1.3 0.1 0.1 22.3 0.1 0.4 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.0 0.9 0.1 0.1 0.2 0.3 0.4 0.1 0.0 0.2 0.1 0.5 15.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.8 0.1 1.1 0.5 3.9 0.1 0.1 1.7 0.2 0.2 0.1 0.6 0.3 0.1 12.2 0.1 0.7 6.6 0.7 1.6 0.7 0.5 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 41.4 0.0 0.1 0.0 1.0 0.7 0.4 0.4 0.3 0.2 4.3 0.4 0.2 0.4 6.6 0.4 0.4 1.6 0.5 0.4 0.7 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.1 0.0 0.3 0.2 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13, UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002853, HPA005498" Approved Approved Vesicles,Cytosol NA NA Vesicles Cytosol "HPA002853: AB_1078131, HPA005498: " "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 20.6 23.0 18.4 23.2 23.2 19.3 24.8 20.9 25.5 21.1 23.3 21.6 22.0 18.0 26.3 28.5 18.3 22.5 22.2 16.8 16.6 16.2 23.5 31.1 19.7 28.4 22.4 16.1 24.2 18.8 13.0 41.7 18.7 19.5 26.7 26.5 16.3 19.5 25.6 11.2 25.2 25.7 23.5 21.6 31.4 20.1 19.0 20.3 23.6 24.5 14.6 25.8 18.3 20.9 10.2 14.4 21.7 12.5 3.4 11.1 7.1 10.9 12.4 11.1 7.0 7.2 10.4 6.3 8.9 9.2 11.5 14.3 12.4 11.5 9.5 17.1 12.3 23.8 6.3 13.2 6.3 12.1 6.8 8.8 5.2 14.0 14.1 10.7 9.5 21.0 12.3 11.8 9.2 20.0 12.0 12.5 10.9 11.6 27.4 11.4 27.8 8.0 8.6 10.2 32.8 17.0 6.2 7.1 13.2 18.3 16.9 6.7 9.8 12.7 7.7 7.7 11.6 6.9 9.2 8.4 9.9 4.9 12.8 17.0 13.2 21.9 15.3 10.6 12.6 7.5 21.7 12.4 12.2 7.8 12.5 7.6 8.4 8.9 7.6 14.4 10.2 11.1 9.1 2.5 3.4 9.4 7.5 10.7 7.1 18.4 23.2 20.9 25.5 16.6 16.2 22.4 16.1 19.5 20.3 14.9 31.5 32.3 54.9 31.3 12.7 15.1 20.4 34.8 25.0 17.4 9.8 22.8 38.1 27.8 14.0 38.3 32.8 0.0 45.1 32.1 22.1 46.9 109.4 26.7 37.3 11.1 25.4 23.4 36.4 6.8 19.8 44.5 27.0 35.1 42.8 12.8 44.6 41.2 15.2 44.0 14.8 25.8 39.0 9.9 16.3 30.9 40.7 34.5 28.5 55.9 ALPI ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456123-232460032 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 406 "intestine: 133.2" "Group enriched" "Detected in some" 6 "Enterocytes: 45.5;Paneth cells: 17.5" "Cancer enhanced" "Detected in many" "liver cancer: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "CACO-2: 12.7" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 63.0 0.0 0.0 57.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.0 0.1 0.1 133.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 17.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 ALPL "HOPS, TNSALP" ENSG00000162551 "Alkaline phosphatase, liver/bone/kidney" P05186 1 21509372-21578412 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 73.3;liver: 52.7;lung: 45.1" "Cell type enhanced" "Detected in many" 15 "Alveolar cells type 2: 88.5;Hepatocytes: 25.3;Ito cells: 25.8;Proximal tubular cells: 44.8;Rod photoreceptor cells: 28.1" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 91 "neutrophil: 73.3" "Lineage enriched" "Detected in single" 127 "granulocytes: 73.3" "Cell line enhanced" "Detected in some" "HSkMC: 53.1;hTEC/SVTERT24-B: 41.5;LHCN-M2: 30.2;SCLC-21H: 26.4;SuSa: 14.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 7300000 Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 15.9 22.7 4.5 17.6 6.0 2.6 10.6 2.2 7.8 2.2 2.1 4.1 0.7 1.9 3.7 1.1 2.0 5.7 2.8 10.9 5.7 4.2 29.7 52.7 45.1 28.1 5.3 4.8 1.2 4.3 2.4 4.1 2.2 7.7 2.6 1.3 18.3 3.1 6.6 0.9 1.8 2.7 2.5 3.8 19.6 1.8 2.9 2.7 0.5 3.7 1.7 3.9 7.1 8.4 0.5 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 2.0 3.3 0.1 0.7 0.2 0.4 0.2 0.0 0.7 2.3 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.6 0.0 1.1 1.1 0.5 0.0 0.2 53.1 0.0 41.5 0.1 0.0 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 12.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 26.4 0.3 0.0 0.0 0.1 14.8 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 4.5 6.0 2.2 7.8 5.7 4.2 5.3 4.8 7.7 2.7 3.0 88.5 0.5 0.5 0.1 2.6 2.0 0.0 1.4 10.3 0.0 0.0 0.0 6.6 0.0 1.2 7.1 0.0 23.3 0.0 0.3 0.3 1.5 7.0 25.3 0.1 1.6 0.0 25.8 1.0 4.4 0.3 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 44.8 28.1 0.0 1.0 0.3 13.6 0.4 1.3 0.0 0.0 0.3 ALPP ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378534-232382889 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "placenta: 240.2" "Group enriched" "Detected in some" 19 "Alveolar cells type 1: 11.9;Club cells: 3.4;Syncytiotrophoblasts: 5.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HaCaT: 88.1;SiHa: 24.3" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 240.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.5 1.6 0.5 1.1 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.0 0.0 88.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 24.3 8.6 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.7 0.5 0.2 0.5 0.3 0.3 0.3 0.1 1.0 0.4 0.4 1.6 1.1 0.5 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 5.6 0.0 0.0 0.0 ALPPL2 ENSG00000163286 "Alkaline phosphatase, placental like 2" P10696 2 232406843-232410714 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.2;lung: 9.4" "Cell type enhanced" "Detected in some" 28 "Alveolar cells type 1: 6.0;Ciliated cells: 1.4;Club cells: 2.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 21.4;HaCaT: 15.7;SuSa: 25.7" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "CAB020698: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.2 1.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.4 21.4 0.0 0.0 0.0 0.0 15.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943293-95968716 "Enzymes, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 99.0" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 125.2" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 19.5;HMC-1: 21.5;Karpas-707: 26.6;SiHa: 17.8;SK-BR-3: 20.0;U-266/70: 21.5;U-266/84: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 410000 Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.1 5.7 0.5 2.4 0.8 2.0 0.9 0.5 1.3 0.7 0.7 0.6 0.4 1.9 0.9 0.5 0.8 0.5 0.7 1.1 0.6 0.5 4.4 99.0 1.3 1.4 0.5 0.4 0.7 1.1 0.0 1.2 0.6 1.0 0.7 0.0 0.8 1.3 0.7 11.3 2.2 1.9 0.6 0.6 2.9 1.9 6.2 0.5 0.7 0.6 0.7 0.7 0.8 0.9 1.5 1.2 3.7 3.8 5.7 1.6 1.4 19.5 4.3 0.3 2.8 0.1 0.0 4.4 0.6 0.2 0.3 0.6 1.9 2.5 1.7 1.9 0.0 1.1 3.7 0.1 0.0 0.1 6.8 0.7 1.9 3.0 3.8 0.0 2.5 21.5 0.0 0.1 0.3 0.0 0.1 0.1 1.7 1.3 26.6 0.0 3.0 1.6 4.8 2.0 0.7 1.0 3.5 0.1 2.2 0.0 1.8 2.2 3.2 17.8 20.0 2.3 0.0 2.1 3.6 0.0 2.8 9.7 3.5 2.4 21.5 25.2 2.7 1.9 5.2 3.1 0.3 1.6 3.7 1.2 1.4 1.1 1.5 0.6 1.6 1.2 1.0 1.0 1.1 1.2 5.7 3.8 0.6 0.3 1.4 0.5 0.8 0.5 0.6 0.6 0.5 0.5 0.4 1.0 0.5 0.0 0.3 2.2 0.2 0.3 0.0 0.4 0.0 0.0 1.2 3.5 0.0 0.5 3.3 0.1 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.0 0.0 125.2 4.1 1.6 1.7 11.1 3.7 0.0 0.3 1.1 3.3 0.0 0.0 1.9 0.3 0.0 0.0 23.2 0.0 0.0 0.0 1.2 1.9 0.3 0.2 2.9 0.0 0.1 AMDHD2 CGI-14 ENSG00000162066 "Amidohydrolase domain containing 2" Q9Y303 16 2520357-2531422 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Hofbauer cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA041184, HPA041321" Enhanced Approved Nucleoli,Cytosol No No 69000 "Nucleoli, Cytosol" "HPA041184: AB_10803998, HPA041321: AB_10795588" "unprognostic (1.20e-1)" "prognostic favorable (5.19e-4)" "unprognostic (7.86e-3)" "unprognostic (2.39e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.48e-2)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-2)" "unprognostic (8.68e-2)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" 12.8 16.9 8.6 11.4 10.1 12.7 10.9 7.3 16.0 9.4 8.8 11.1 11.3 19.5 10.4 11.9 8.4 9.0 14.6 11.8 7.1 4.8 15.3 10.5 20.0 15.8 9.8 11.3 8.1 10.1 6.5 7.5 10.7 8.9 8.6 2.4 10.9 16.1 9.6 10.2 15.0 19.1 7.2 8.3 22.2 11.5 25.7 7.9 7.3 9.9 11.0 8.9 9.3 8.0 9.8 17.1 16.6 15.8 4.9 8.1 4.8 6.5 8.8 1.9 4.0 2.1 1.7 14.3 5.9 2.5 4.7 5.9 6.3 11.6 3.0 4.2 1.1 10.1 6.0 1.1 1.6 0.1 3.8 5.3 4.3 7.9 8.2 8.0 3.1 14.1 4.0 1.7 3.4 0.5 1.2 2.9 8.5 9.8 7.2 1.9 15.6 5.1 8.6 4.1 0.5 6.8 19.7 3.0 11.0 1.3 3.6 7.3 7.2 3.8 9.2 15.5 0.3 9.5 0.8 4.0 5.3 8.1 10.5 3.0 15.2 9.7 5.9 5.9 5.9 6.6 9.9 6.1 16.5 7.4 15.8 5.5 9.8 5.9 5.3 2.3 7.4 5.0 4.2 16.6 4.9 15.2 17.1 8.1 4.8 8.6 10.1 7.3 16.0 7.1 4.8 9.8 11.3 8.9 7.9 3.0 12.3 13.1 4.6 7.9 9.0 2.0 7.6 5.3 2.3 5.2 5.9 14.1 5.0 24.6 45.6 7.1 18.1 0.0 14.7 23.4 8.0 6.0 6.9 10.4 104.3 22.3 12.1 18.4 33.6 16.0 9.8 15.9 18.6 34.3 9.0 10.8 16.8 14.4 6.0 38.1 12.0 0.0 4.4 7.7 17.2 7.9 23.3 15.3 7.0 3.8 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 212.4" "Cell type enhanced" "Detected in some" 19 "Late spermatids: 1.5;Melanocytes: 1.7" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 31 "memory B-cell: 3.0" "Lineage enriched" "Detected in single" 31 "B-cells: 3.0" "Cell line enriched" "Detected in single" 32 "U-266/70: 14.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 2.9 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.2 3.3 0.0 0.0 3.5 0.1 3.3 1.4 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.6 1.2 0.0 2.1 1.5 212.4 0.1 1.4 0.0 0.1 0.5 0.7 0.1 0.0 0.0 0.2 25.3 2.8 0.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 64.4" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 58.9;Horizontal cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.8;granulocytes: 29.7;monocytes: 24.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760, HPA050590" Approved Enhanced Cytosol NA NA 380000 Cytosol "HPA027137: AB_2672129, HPA045760: AB_2679443, HPA050590: AB_2681184" "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" "unprognostic (9.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.78e-10)" "unprognostic (9.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" 8.1 22.7 20.2 21.7 41.3 64.4 4.9 16.3 26.8 9.5 10.1 9.5 6.3 17.1 9.0 6.0 5.9 11.8 13.2 5.2 21.7 19.4 7.8 13.0 8.2 10.7 14.2 14.2 16.3 9.4 13.0 37.1 10.8 18.3 9.7 5.7 15.7 9.1 12.2 2.1 10.0 11.6 9.1 8.5 15.9 8.3 5.3 12.2 10.3 6.4 3.0 7.5 8.2 8.1 2.8 8.8 29.7 24.5 3.0 4.3 5.4 10.9 12.7 18.7 15.8 16.3 16.3 7.1 15.6 31.9 16.0 15.8 9.7 4.7 5.4 12.0 29.2 10.5 8.6 9.8 14.5 9.9 8.7 13.2 28.5 16.7 10.8 15.3 12.1 30.7 18.3 7.7 21.1 16.4 28.9 13.8 11.9 8.8 14.7 11.4 16.9 17.9 29.0 12.1 10.2 13.6 12.7 7.2 8.4 14.7 6.7 14.5 15.3 10.6 13.0 12.6 7.0 7.3 11.3 13.1 19.8 23.0 24.1 16.0 29.5 14.3 7.8 29.5 18.8 20.6 0.5 9.2 11.2 3.4 19.6 4.3 2.8 3.3 3.4 8.8 1.7 3.8 2.8 29.7 3.0 24.5 1.4 2.6 5.4 20.2 41.3 16.3 26.8 21.7 19.4 14.2 14.2 18.3 12.2 3.0 8.5 8.3 4.7 7.9 35.7 2.5 17.8 4.0 5.7 0.0 58.9 4.0 6.6 9.7 2.9 6.2 3.9 0.0 9.6 7.4 11.8 4.5 3.5 17.8 10.5 49.3 16.8 6.2 37.8 1.3 12.0 28.6 5.0 1.0 8.6 9.1 8.3 0.0 20.1 3.9 5.8 12.9 11.7 4.5 2.6 7.0 2.2 10.1 9.7 3.4 AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.2;skeletal muscle: 61.0" "Cell type enhanced" "Detected in many" 7 "Erythroid cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;CAPAN-2: 19.3;HMC-1: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038662, HPA047408" Uncertain Approved "Nuclear membrane" NA NA "Nuclear membrane" "HPA038662: AB_2676136, HPA047408: AB_2680034" "unprognostic (2.24e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-2)" "prognostic favorable (2.37e-4)" "unprognostic (1.89e-2)" "unprognostic (1.71e-3)" "unprognostic (2.91e-3)" "unprognostic (1.25e-1)" "unprognostic (7.83e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-1)" "unprognostic (3.06e-2)" "unprognostic (7.07e-2)" "unprognostic (4.42e-2)" "unprognostic (2.98e-1)" "unprognostic (2.12e-2)" 2.9 13.7 5.3 13.8 14.0 39.2 2.3 2.3 7.8 3.3 3.4 19.6 0.7 4.7 3.1 4.2 5.2 8.0 4.6 2.1 7.4 7.1 4.2 1.5 4.5 12.7 15.2 5.7 2.3 2.5 24.9 14.5 3.7 11.2 5.5 4.9 4.3 4.7 2.8 61.0 10.8 5.0 3.1 12.8 8.3 4.6 1.4 12.6 14.8 2.7 7.6 14.2 6.1 5.1 7.6 3.9 17.0 6.0 3.3 5.3 2.3 7.6 1.1 0.3 0.1 4.1 2.9 0.4 6.9 24.7 1.7 1.8 3.8 19.3 2.8 0.7 3.1 6.8 4.8 0.1 6.5 5.1 6.9 0.2 6.8 1.0 0.5 1.4 9.2 20.5 10.8 10.2 3.4 4.4 4.3 0.7 4.6 10.3 3.0 5.6 0.2 5.4 12.1 0.9 0.6 6.8 2.0 9.0 9.9 0.3 6.5 2.9 1.5 1.5 0.2 0.4 0.6 0.2 3.1 1.9 7.9 0.1 5.4 0.2 2.7 1.5 3.0 9.0 9.2 0.2 6.6 6.0 17.0 2.3 3.8 5.3 7.6 3.3 2.5 3.9 5.8 3.7 2.5 8.3 3.3 1.6 2.5 1.9 2.3 5.3 14.0 2.3 7.8 7.4 7.1 15.2 5.7 11.2 12.6 0.0 4.6 5.2 8.9 11.1 20.7 5.6 7.6 12.0 7.9 14.0 2.0 0.7 14.9 2.4 7.0 1.0 1.7 46.7 1.4 1.1 1.4 17.1 11.5 0.6 13.4 0.0 9.8 1.8 14.3 14.2 0.9 9.1 3.3 13.6 3.2 6.8 3.9 2.9 0.0 1.0 1.3 0.0 1.7 0.2 0.5 10.9 1.0 2.9 2.2 16.1 AMY1A AMY1 ENSG00000237763 "Amylase, alpha 1A (salivary)" P04745 1 103655290-103664554 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 100 "salivary gland: 654.0" "Cell type enriched" "Detected in some" 11 "Ciliated cells: 38.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 1.4;SH-SY5Y: 2.4" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" NA NA 68000000 "CAB004310: AB_626668, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 654.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.3 0.3 0.6 0.0 1.1 0.7 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.6 0.0 0.1 1.1 0.1 0.3 0.1 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.7 3.0 2.1 0.0 0.8 0.6 0.0 2.4 0.0 38.8 3.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 AMY1B AMY1 ENSG00000174876 "Amylase, alpha 1B (salivary)" P04745 1 103687415-103696680 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "salivary gland: 302.4" "Cell type enriched" "Detected in some" 10 "Ciliated cells: 34.8" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;SH-SY5Y: 2.1;U-266/70: 1.8" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 68000000 "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 6.5 0.2 0.2 0.2 0.0 0.2 0.2 0.2 4.0 0.2 0.2 0.2 0.0 0.2 0.2 0.7 0.2 0.2 0.2 0.2 23.0 0.0 0.2 0.2 0.2 0.2 0.0 0.2 302.4 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 1.1 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.6 0.0 1.1 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.5 1.2 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.6 0.0 0.1 1.1 0.1 0.3 0.1 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.7 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 3.0 3.2 0.0 0.1 0.2 0.0 0.7 0.0 34.8 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 AMY1C AMY1 ENSG00000187733 "Amylase, alpha 1C (salivary)" P04745 1 103750406-103758690 "Enzymes, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 34.3;salivary gland: 62.5" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 33.4;Ciliated cells: 95.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "THP-1: 3.7" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 68000000 "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 9.6 4.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 33.4 0.0 0.0 0.0 0.0 0.4 0.0 95.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMY2A AMY2 ENSG00000243480 "Amylase, alpha 2A (pancreatic)" P04746 1 103616811-103625780 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "pancreas: 1849.4" "Cell type enriched" "Detected in some" 68 "Exocrine glandular cells: 849.6" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "THP-1: 1.0;U-2 OS: 1.3" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" NA NA 77000000 "CAB045960: AB_2226891, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.9 1849.4 0.0 0.2 0.2 0.2 0.2 0.0 0.2 59.9 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.9 1.5 0.0 0.0 0.0 849.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 AMY2B AMY2 ENSG00000240038 "Amylase, alpha 2B (pancreatic)" P19961 1 103553815-103579534 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pancreas: 939.9" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 31.4;Exocrine glandular cells: 124.1" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "classical monocyte: 8.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 11.5;EFO-21: 11.8;HSkMC: 7.8" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 75000000 "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 1.7 0.5 0.8 0.8 1.5 0.4 1.0 2.6 0.8 0.9 0.9 0.8 0.8 0.5 0.8 1.0 0.8 1.5 0.9 1.1 0.8 0.5 1.5 1.1 1.0 1.1 1.0 0.9 1.2 939.9 0.8 1.1 0.8 0.8 0.9 0.4 0.9 145.7 1.0 1.7 1.3 0.9 0.8 0.8 1.0 0.4 0.8 0.8 0.8 2.4 1.1 0.8 0.8 0.8 1.8 2.6 1.9 8.5 0.1 1.1 1.9 0.0 0.6 1.3 0.0 6.4 11.5 1.2 0.9 0.9 0.7 1.7 0.0 0.2 1.1 11.8 0.3 0.0 1.4 0.1 1.4 1.6 1.4 1.8 2.1 4.4 0.9 1.0 2.6 2.8 7.8 7.7 0.8 1.3 2.0 0.2 3.3 0.0 3.5 0.9 0.0 2.1 0.5 0.1 0.1 1.6 0.6 0.0 5.1 6.6 2.1 3.2 0.6 2.7 1.3 0.8 2.1 0.1 1.5 0.9 0.4 1.0 0.5 0.7 4.0 0.1 0.3 2.2 2.0 0.2 0.0 8.5 1.7 0.8 3.9 0.6 1.7 0.3 0.4 2.6 1.8 1.1 0.4 1.9 0.1 3.6 0.8 0.3 1.9 0.8 1.5 2.6 0.8 0.8 0.5 1.0 0.9 0.8 0.8 11.9 16.1 3.2 2.8 4.1 10.0 6.9 5.1 17.4 18.2 1.8 31.4 0.3 0.0 0.7 4.8 1.5 3.6 0.0 124.1 0.2 1.4 1.2 3.5 5.9 1.5 9.5 4.7 1.8 7.0 2.3 2.3 3.1 5.0 1.8 2.5 2.4 1.3 1.4 1.8 0.4 16.2 0.0 2.2 1.7 0.6 2.6 0.2 0.8 2.5 0.9 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784889-89815401 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 195.3;kidney: 78.7;pancreas: 93.9" "Cell type enhanced" "Detected in many" 16 "Cholangiocytes: 372.0;Enterocytes: 993.7;Exocrine glandular cells: 328.5;Proximal tubular cells: 388.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "neutrophil: 59.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 59.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.5;BJ: 78.2;BJ hTERT+: 111.8;fHDF/TERT166: 67.0;HMC-1: 71.1;HSkMC: 68.7;HUVEC TERT2: 87.5;TIME: 87.4;U-2197: 95.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1500000000 "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 21.3 1.1 0.6 2.9 0.8 9.5 17.0 1.0 1.3 8.2 21.2 0.8 0.5 195.3 1.4 8.4 3.6 1.4 27.7 3.7 0.4 0.3 78.7 37.7 9.7 9.3 0.9 0.9 1.8 93.9 0.0 0.7 14.7 1.3 8.6 4.7 4.0 6.6 1.8 1.6 4.9 155.8 4.3 1.2 7.2 0.8 4.7 0.2 5.6 1.5 4.2 3.8 4.7 3.0 0.0 6.9 59.4 12.8 0.0 0.0 5.5 0.0 5.0 0.0 0.0 61.3 78.5 0.5 78.2 111.8 9.6 8.5 0.5 0.0 0.0 0.9 67.0 0.0 0.0 0.6 0.0 3.8 0.0 0.0 14.7 0.4 11.7 36.1 1.0 71.1 68.7 0.1 30.2 0.0 0.4 87.5 0.0 0.4 0.1 3.7 0.0 0.0 34.7 0.2 0.0 5.3 0.0 0.0 0.8 43.7 0.0 0.1 0.7 0.0 0.1 0.0 0.1 0.0 6.8 87.4 42.2 0.0 95.3 0.0 0.0 0.0 0.0 0.1 0.0 2.2 5.7 12.8 10.4 0.0 7.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 59.4 0.0 12.0 0.1 0.0 5.5 0.6 0.8 1.0 1.3 0.4 0.3 0.9 0.9 1.3 0.2 0.0 4.8 8.2 3.1 8.9 0.0 0.8 372.0 2.7 20.5 19.2 0.0 9.7 36.5 10.6 0.1 1.8 993.7 0.0 328.5 12.0 36.3 18.0 24.2 144.7 39.4 0.0 2.9 101.9 51.7 0.0 2.6 46.4 3.3 39.7 10.5 0.0 120.5 201.5 1.4 388.5 0.0 25.8 5.0 0.4 0.1 5.1 5.4 1.0 18.3 1.3 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512949-36724549 "Enzymes, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 54.6;lymphoid tissue: 57.4" "Cell type enhanced" "Detected in many" 17 "Hofbauer cells: 31.1;Kupffer cells: 110.3;Macrophages: 54.2;T-cells: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 54.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 4.1;NB-4: 21.3;THP-1: 16.3;U-937: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 8.4 3.4 5.2 17.2 4.9 19.3 2.8 1.9 3.6 3.1 5.3 7.4 0.2 4.9 3.9 7.2 2.5 3.1 8.4 3.4 4.8 3.8 3.1 6.8 9.4 23.2 6.9 2.0 2.1 2.3 0.6 2.4 5.7 5.8 3.8 7.3 3.8 4.5 1.4 1.5 1.6 7.6 4.7 12.6 57.4 3.3 1.4 6.8 14.0 2.9 0.4 10.9 7.2 2.8 0.3 34.8 18.7 54.6 19.2 8.8 31.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.5 0.0 0.0 0.0 2.9 0.0 0.3 0.1 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 21.3 0.1 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 0.3 54.6 17.6 8.8 47.9 1.8 0.3 0.4 6.1 34.8 0.0 1.0 7.8 18.7 19.2 20.2 0.5 0.1 31.0 5.2 4.9 1.9 3.6 4.8 3.8 6.9 2.0 5.8 6.8 0.0 14.0 8.8 0.0 0.7 0.0 0.4 0.0 1.4 4.5 0.0 0.0 0.2 1.7 0.2 0.4 0.5 5.8 0.0 0.0 0.2 0.5 0.1 4.7 0.6 31.1 0.0 14.9 3.1 110.3 0.4 0.0 54.2 0.0 19.0 0.4 3.2 0.0 1.5 0.4 0.3 0.2 0.0 0.9 0.0 0.0 0.3 0.1 51.7 0.5 0.1 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674002-49683963 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol No No 1600000 Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 12.3 31.4 14.3 16.9 18.4 17.3 13.5 14.2 28.2 13.4 23.5 14.4 25.3 24.2 14.1 19.0 23.8 17.2 19.1 23.1 14.2 14.2 33.6 36.9 15.0 23.9 13.9 20.0 13.9 22.7 33.5 26.6 18.6 16.3 16.1 26.6 19.5 19.8 19.8 55.1 16.9 21.7 14.1 9.8 19.2 21.9 22.3 11.7 22.6 26.6 26.6 20.7 19.9 13.7 20.5 26.2 30.4 27.9 21.8 29.5 28.1 25.8 21.1 23.2 30.0 20.3 13.6 30.7 16.9 21.7 23.8 25.5 34.0 28.1 33.1 19.0 19.2 21.7 24.0 25.9 39.2 18.1 15.7 10.7 35.7 35.3 27.8 20.1 38.2 55.6 15.4 29.6 13.6 28.3 23.8 21.5 23.3 22.1 16.5 23.6 23.9 26.9 19.4 13.7 37.3 19.3 10.2 19.9 43.0 47.1 61.4 11.1 19.3 19.1 46.4 21.0 17.9 30.6 20.4 9.7 14.7 25.8 23.0 22.8 18.9 13.5 19.7 25.4 27.1 21.2 30.2 25.5 30.4 28.5 27.9 22.5 20.5 23.5 26.7 26.2 17.4 24.9 24.2 8.0 21.8 26.7 21.0 29.5 28.1 14.3 18.4 14.2 28.2 14.2 14.2 13.9 20.0 16.3 11.7 38.7 22.3 16.0 19.8 7.7 7.8 42.0 33.1 9.4 20.5 26.2 11.8 72.6 36.5 39.0 4.6 8.3 73.8 23.3 30.4 54.6 12.8 15.2 23.1 65.2 45.5 7.9 25.4 14.1 36.8 8.1 14.1 18.1 20.3 22.6 44.7 21.8 35.8 28.8 12.7 64.9 9.9 12.9 14.2 30.5 28.4 8.2 51.9 25.3 51.1 21.0 APOBEC1 "APOBEC-1, BEDP, CDAR1, HEPR" ENSG00000111701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 1" P41238 12 7649400-7665903 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "intestine: 56.1" "Cell type enhanced" "Detected in some" 23 "Cholangiocytes: 7.6;Enterocytes: 23.9;Paneth cells: 31.7" "Group enriched" "Detected in some" 9 "colorectal cancer: 6.2;pancreatic cancer: 6.1;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "CAPAN-2: 6.2;OE19: 8.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "unprognostic (2.35e-1)" "unprognostic (3.80e-4)" "unprognostic (7.96e-3)" "unprognostic (1.79e-1)" "unprognostic (4.38e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 23.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 56.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 2.5 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 APOBEC2 "ARCD1, ARP1" ENSG00000124701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 2" Q9Y235 6 41053304-41064511 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "heart muscle: 58.4;skeletal muscle: 163.0;tongue: 53.9" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 89.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 4.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 9.0;HSkMC: 3.1;SuSa: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014252, HPA017957" Enhanced NA NA "HPA014252: AB_1844932, HPA017957: AB_1844933" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-1)" "unprognostic (2.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (7.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-1)" "unprognostic (2.01e-2)" "unprognostic (7.02e-2)" "unprognostic (3.69e-1)" "unprognostic (1.31e-3)" "unprognostic (2.19e-2)" 1.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 6.1 2.8 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.0 1.6 0.0 0.1 3.2 0.0 163.0 0.2 0.2 0.4 0.0 0.0 2.2 0.5 0.0 1.3 0.5 53.9 4.2 0.1 0.0 5.5 5.5 3.6 2.4 1.5 4.8 0.4 0.1 0.0 0.5 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.1 0.0 0.6 0.0 1.0 0.1 3.1 0.0 0.0 0.0 0.1 0.0 1.4 0.5 0.4 0.0 0.0 0.2 1.0 0.1 1.3 0.1 0.5 0.5 0.1 0.1 0.0 1.2 0.3 0.0 0.0 0.1 2.4 0.2 0.1 0.0 0.0 0.3 0.4 0.1 1.7 0.3 0.8 0.2 0.5 0.0 1.3 2.0 3.6 4.4 1.3 3.5 4.3 4.0 4.8 1.1 5.5 4.2 4.6 1.6 1.5 2.4 5.5 3.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 2.3 89.6 0.0 0.0 0.0 0.0 2.0 1.4 0.0 2.5 9.7 0.0 0.0 0.0 18.9 5.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 19.0 0.3 0.0 1.7 0.0 0.0 1.0 3.5 0.0 0.0 1.1 2.6 0.0 0.1 0.2 0.2 0.0 1.1 0.0 0.0 0.0 APTX "AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157" ENSG00000137074 Aprataxin Q7Z2E3 9 32972606-33025168 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064930 Supported Supported Nucleoplasm,Nucleoli No No "Nucleoplasm, Nucleoli" "HPA064930: AB_2685386" "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (4.04e-1)" "unprognostic (8.16e-2)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-3)" "unprognostic (3.48e-3)" "unprognostic (3.49e-2)" "prognostic favorable (6.01e-5)" "unprognostic (7.87e-2)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.50e-2)" 12.9 20.3 17.5 11.2 18.4 19.9 16.5 15.1 21.7 12.0 15.2 19.3 9.3 11.7 14.7 12.9 19.1 14.7 8.0 11.9 13.3 13.9 17.9 23.4 12.6 11.8 16.4 16.5 11.8 14.3 15.8 14.3 12.1 20.2 12.1 18.1 14.6 12.5 11.9 14.1 20.6 13.8 14.6 15.7 11.7 12.5 18.2 14.5 8.8 10.5 12.6 16.1 13.4 12.1 17.1 18.4 16.1 20.8 26.4 19.4 15.0 21.6 16.4 12.5 10.8 12.8 11.2 16.6 14.5 15.1 17.7 19.6 21.8 7.7 16.9 8.7 12.1 11.0 11.5 20.3 19.4 22.0 22.8 8.3 10.0 23.5 22.2 14.8 16.1 9.6 15.0 23.8 20.3 26.4 11.3 16.9 13.1 15.1 16.9 16.5 9.3 14.4 23.7 19.1 14.2 17.7 13.1 8.7 12.0 14.5 13.2 8.7 7.3 13.3 11.9 9.7 12.1 13.5 6.6 10.4 9.9 13.2 17.1 14.9 7.3 12.0 16.9 14.7 13.2 7.9 9.1 17.7 14.9 13.4 16.3 17.6 17.0 15.2 15.5 18.4 17.1 18.0 14.6 16.1 26.4 20.8 17.9 19.4 15.0 17.5 18.4 15.1 21.7 13.3 13.9 16.4 16.5 20.2 14.5 17.9 31.9 15.7 18.7 14.8 13.6 12.9 28.1 25.4 19.4 8.7 9.8 23.7 24.9 20.4 49.1 11.9 11.6 0.0 24.6 22.8 12.6 16.4 16.1 17.4 16.5 12.7 16.1 6.7 15.2 35.4 12.4 14.5 13.5 20.8 12.6 17.8 24.5 3.5 9.9 24.1 16.2 12.9 12.2 35.9 27.0 18.4 23.3 14.1 15.1 20.4 AQR "fSAP164, IBP160, KIAA0560" ENSG00000021776 "Aquarius intron-binding spliceosomal factor" O60306 15 34851782-34969839 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040624, HPA055647" Enhanced Nucleoplasm No No Nucleoplasm "HPA040624: AB_2677050, HPA055647: AB_2682874" "unprognostic (1.73e-1)" "unprognostic (3.71e-2)" "unprognostic (2.97e-1)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (9.04e-2)" "unprognostic (4.25e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-2)" "unprognostic (2.65e-1)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "prognostic favorable (4.83e-4)" "unprognostic (2.97e-1)" "unprognostic (2.47e-1)" "unprognostic (3.84e-1)" "unprognostic (3.13e-2)" 15.5 15.8 8.0 14.0 12.4 9.7 16.1 11.2 14.3 16.6 11.2 11.8 8.7 9.2 18.5 11.8 18.3 12.3 8.7 9.9 8.4 7.5 14.4 11.2 10.7 12.6 8.7 6.9 15.5 13.6 16.8 13.2 15.3 13.2 12.0 11.8 12.4 15.1 11.3 8.7 14.2 13.0 14.3 8.3 16.8 12.9 15.8 9.2 27.9 14.8 8.5 16.5 15.7 14.9 5.9 5.5 7.1 5.1 4.5 6.5 2.9 5.0 13.1 8.7 9.1 11.8 11.0 4.5 6.2 7.9 8.3 7.5 5.9 3.1 4.1 4.0 10.5 5.5 8.0 14.6 8.9 9.2 5.8 5.9 13.2 11.6 5.4 6.7 10.7 6.2 8.5 5.9 6.5 6.9 7.8 7.0 3.3 9.3 4.1 8.2 3.4 6.2 7.2 8.6 11.7 5.4 8.5 15.0 4.1 8.4 8.9 9.5 7.4 10.1 9.7 2.2 8.0 6.8 8.4 9.1 6.2 3.4 4.2 5.5 5.0 6.1 8.4 7.7 9.3 6.2 7.1 4.7 2.7 6.5 5.1 5.7 4.0 5.7 6.2 3.8 5.9 5.8 6.4 2.3 4.5 3.0 5.5 4.6 2.9 8.0 12.4 11.2 13.4 8.4 7.5 8.7 6.9 13.2 9.2 11.9 27.0 11.9 11.9 8.5 25.3 14.6 20.4 29.4 36.4 14.0 108.0 13.3 3.3 11.5 36.0 17.9 15.5 0.0 12.3 12.0 10.6 12.5 23.1 17.1 13.1 23.8 12.7 31.9 17.0 6.9 19.2 12.7 15.1 13.6 17.7 17.4 15.9 14.0 17.3 10.3 38.7 6.5 9.8 19.3 20.1 8.4 11.1 20.8 19.1 11.2 ARG1 ENSG00000118520 "Arginase 1" P05089 6 131573144-131584332 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 284.1" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 867.5" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "neutrophil: 24.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.4" "Cell line enhanced" "Detected in some" "Daudi: 1.5;Hep G2: 1.7;HL-60: 4.0;RH-30: 1.6;SiHa: 1.8;U-698: 2.2" "Region enhanced" "Detected in single" "cerebellum: 2.7" "Not detected" "Not detected" "HPA003595, CAB009434, HPA024006, CAB056159" Enhanced NA NA 15000000 "CAB009434: AB_2058955, CAB056159: AB_2665582, HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" 1.0 0.0 0.1 0.1 0.1 34.3 0.6 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.3 0.1 3.0 0.2 0.0 0.1 284.1 5.1 0.8 0.2 0.1 0.4 0.2 0.0 0.1 1.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 14.6 0.1 0.1 0.1 3.5 0.0 0.3 0.1 0.5 0.3 1.7 0.3 0.3 0.7 0.1 0.1 24.4 0.4 0.0 4.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.2 1.7 0.0 4.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.6 0.0 0.5 0.1 0.4 0.1 0.0 0.0 0.0 1.6 0.4 0.0 0.3 0.2 0.1 1.8 0.4 0.3 0.2 0.1 0.5 0.0 0.0 0.2 0.3 0.1 1.0 0.2 2.2 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.1 24.4 0.0 0.4 0.1 4.7 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.0 0.0 13.9 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.0 867.5 0.0 0.0 0.0 25.2 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619798-67651720 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 53.7;thyroid gland: 75.4" "Cell type enhanced" "Detected in many" 17 "Basal glandular cells: 140.3;Collecting duct cells: 157.1;Syncytiotrophoblasts: 502.9;Urothelial cells: 134.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 24.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria NA NA Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 1.5 3.9 2.4 1.7 6.4 0.6 2.7 8.3 5.3 9.3 5.4 0.5 2.0 2.1 3.7 2.3 7.3 0.8 4.9 2.1 3.3 5.5 41.4 2.0 1.7 0.6 3.2 1.7 8.8 2.6 32.1 22.5 4.4 4.6 53.7 1.1 3.4 26.6 3.8 17.2 0.8 10.4 2.2 3.9 0.7 1.4 1.9 2.1 0.1 75.4 13.6 2.2 5.3 4.1 2.5 1.7 2.0 1.4 0.3 2.9 3.4 3.5 0.5 6.2 4.0 0.9 0.0 8.4 2.7 7.5 9.0 15.3 15.3 1.8 6.0 0.7 1.8 4.1 0.8 24.9 11.3 11.0 0.2 6.2 2.7 1.1 17.4 2.7 0.6 16.3 0.4 14.7 4.4 21.5 0.7 15.3 16.1 7.9 0.0 0.6 1.7 0.9 0.6 11.8 1.5 0.2 0.2 0.8 6.8 7.3 5.9 13.8 5.2 1.7 1.7 2.6 15.0 6.4 0.2 3.1 2.7 6.9 0.2 2.0 0.5 0.9 2.0 5.5 3.1 4.6 0.3 1.4 2.0 1.1 0.5 0.5 0.7 0.3 0.9 1.7 2.5 0.6 0.6 1.7 0.3 1.2 0.1 2.9 3.4 2.4 6.4 8.3 5.3 3.3 5.5 3.2 1.7 4.6 2.1 0.0 4.3 3.7 140.3 7.8 5.0 5.0 2.5 2.7 27.3 157.1 9.8 82.0 31.5 9.2 12.3 3.0 14.8 23.3 2.8 5.2 3.7 84.0 6.9 1.5 12.3 9.5 35.3 1.8 0.3 1.0 0.3 3.9 10.1 1.0 4.3 40.7 4.5 3.5 0.4 75.6 16.0 6.5 4.1 7.2 2.6 4.6 502.9 5.0 3.3 134.9 ARSA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 87.0;Late spermatids: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 4500000 "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favorable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" 19.0 15.2 14.0 15.2 15.7 16.6 15.2 11.9 17.9 12.0 20.3 21.4 26.4 30.2 13.3 21.4 15.6 18.5 23.3 18.8 13.4 8.8 17.5 24.1 15.7 16.8 19.1 10.3 9.3 45.4 13.1 20.4 18.5 17.3 15.8 8.8 14.0 36.8 21.9 6.3 11.1 23.4 8.7 13.2 25.6 23.6 27.2 17.9 10.6 18.7 7.5 16.5 14.8 13.3 5.6 15.7 30.1 19.8 3.9 8.9 7.7 4.1 5.8 2.8 5.4 20.9 11.4 7.0 6.7 8.2 2.9 5.0 1.6 6.4 2.8 4.1 11.0 5.4 6.4 0.6 6.2 0.4 1.2 4.4 1.6 6.5 5.8 14.5 2.4 17.1 13.5 12.1 4.8 3.1 9.9 6.6 5.8 1.7 39.3 5.9 4.7 2.2 2.8 0.8 4.3 5.8 2.0 0.2 12.9 4.9 6.4 1.3 4.3 9.5 8.5 4.8 2.6 3.8 3.0 11.6 2.1 8.0 7.5 1.9 9.3 0.8 2.1 6.1 2.2 6.9 4.3 13.7 17.1 8.9 16.0 7.9 5.6 6.5 7.3 11.2 5.6 3.9 5.3 30.1 3.9 19.8 15.7 8.5 7.7 14.0 15.7 11.9 17.9 13.4 8.8 19.1 10.3 17.3 17.9 6.0 11.7 17.5 11.1 4.1 4.9 6.5 30.6 13.4 4.5 12.2 3.9 10.2 1.7 28.6 51.1 7.9 87.0 23.3 18.7 18.1 13.0 12.6 5.8 27.6 33.4 6.4 35.3 9.2 28.5 100.4 10.0 17.4 16.9 37.9 23.2 9.3 25.7 35.9 5.6 20.6 6.2 0.0 4.7 43.1 3.1 4.8 11.1 10.5 19.0 14.9 ARSB ENSG00000113273 "Arylsulfatase B" P15848 5 78777209-78986087 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 17.2" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.2;monocytes: 5.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037770, HPA037771" Approved Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Golgi apparatus" "HPA037770: AB_10671719, HPA037771: AB_10671720" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-2)" "unprognostic (7.34e-2)" "unprognostic (2.65e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (2.48e-2)" "unprognostic (9.57e-3)" "unprognostic (9.88e-2)" "unprognostic (6.54e-3)" "prognostic unfavorable (3.42e-4)" 15.2 8.4 7.7 9.9 8.9 9.4 11.4 6.2 10.4 7.8 8.7 10.8 2.6 4.0 14.1 6.7 8.6 6.7 12.0 13.0 7.7 5.8 23.2 9.3 10.8 17.2 7.1 6.1 6.1 9.6 10.7 6.1 14.7 7.1 7.5 10.5 12.1 5.2 9.3 5.3 3.4 6.0 18.0 8.3 10.9 7.9 4.1 5.6 7.2 6.4 4.0 6.2 10.3 5.6 1.2 5.5 17.2 5.7 0.1 0.6 1.6 2.3 5.6 9.0 2.9 22.0 8.7 8.3 13.1 11.5 9.7 12.0 4.9 4.3 2.7 14.1 12.7 14.8 1.9 3.4 3.7 9.6 23.3 2.6 4.4 5.9 18.7 5.0 4.9 5.3 10.1 1.2 10.2 3.4 8.1 11.4 1.7 0.9 6.4 9.8 4.5 2.3 9.2 2.7 0.5 2.9 3.4 5.4 2.9 6.1 3.0 3.2 7.4 9.8 3.1 5.7 6.6 3.4 12.8 7.5 8.7 5.0 3.9 11.6 5.5 9.9 3.6 10.6 10.6 19.8 10.5 5.7 17.2 0.6 4.6 0.4 1.2 0.3 0.3 5.5 1.1 0.2 0.4 3.3 0.1 3.7 4.0 0.5 1.6 7.7 8.9 6.2 10.4 7.7 5.8 7.1 6.1 7.1 5.6 0.0 1.3 3.0 1.3 0.7 3.0 5.8 2.5 4.0 0.0 3.5 5.9 1.8 3.3 3.1 0.4 4.3 0.6 0.0 7.9 4.0 9.3 1.9 0.0 3.4 15.4 6.4 1.2 13.5 23.4 0.2 4.0 12.6 13.5 15.4 5.6 3.0 4.4 3.5 3.5 17.2 2.7 6.5 3.1 1.1 1.9 1.1 2.2 2.9 1.9 0.9 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease mutation, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Hofbauer cells: 805.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 27.0;classical monocyte: 53.6;eosinophil: 36.5;intermediate monocyte: 77.9;myeloid DC: 20.8;neutrophil: 73.8;non-classical monocyte: 80.5" "Group enriched" "Detected in all" 6 "dendritic cells: 20.8;granulocytes: 73.8;monocytes: 80.5" "Cell line enhanced" "Detected in all" "ASC diff: 72.7;SK-MEL-30: 103.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 410000 "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 41.9 16.8 18.5 11.2 20.7 20.7 44.2 17.6 19.1 23.9 18.5 15.4 31.5 11.9 17.6 30.6 19.8 16.2 22.3 120.4 17.5 19.2 45.0 13.2 57.2 40.2 27.0 16.7 13.0 16.5 18.0 28.2 36.5 29.8 19.5 19.7 33.3 20.4 39.4 18.2 16.4 16.4 19.5 40.9 25.9 12.9 8.2 15.9 4.5 73.4 15.1 12.3 31.4 16.0 9.8 20.8 73.8 80.5 6.7 6.0 38.7 8.4 11.7 4.6 11.4 72.7 8.6 7.1 8.6 12.3 4.2 7.5 6.2 11.7 5.2 11.0 9.5 28.9 11.1 2.8 4.5 5.2 4.0 6.8 23.3 8.8 16.8 19.9 4.7 26.1 18.5 15.6 6.1 4.2 9.7 1.1 9.0 4.1 11.1 12.1 8.5 2.6 8.4 5.4 18.3 7.2 3.3 4.6 7.0 20.1 48.1 7.6 10.1 8.0 26.4 103.3 6.7 8.6 5.4 7.5 5.5 7.9 10.0 4.1 13.7 30.8 3.8 16.3 10.7 4.4 27.0 53.6 36.5 6.0 77.9 5.4 9.8 4.5 4.5 20.8 7.7 5.3 4.8 73.8 6.7 80.5 3.9 4.9 38.7 18.5 20.7 17.6 19.1 17.5 19.2 27.0 16.7 29.8 15.9 294.8 337.4 90.6 70.3 52.1 87.7 644.7 119.8 140.5 197.9 427.5 43.2 150.6 51.4 112.4 1.9 67.4 63.2 140.2 91.9 53.3 103.9 123.4 247.5 40.0 805.1 73.1 94.1 132.6 474.5 1.9 82.0 445.8 301.9 103.6 90.2 564.6 58.0 94.7 99.3 242.2 72.1 174.6 116.2 11.2 53.7 56.1 123.9 47.3 78.2 113.1 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50248610 "Enzymes, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "intestine: 43.9" "Cell type enhanced" "Detected in many" 9 "Late spermatids: 6.0;Muller glia cells: 10.2;Sertoli cells: 6.5" "Low cancer specificity" "Detected in single" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" NA NA 1200000 "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.3 1.1 0.6 0.2 0.9 0.0 0.5 0.5 1.3 1.7 0.5 43.9 0.7 0.3 0.7 0.5 0.2 0.9 0.5 1.4 0.6 1.6 0.4 0.2 1.2 1.4 1.5 0.3 1.0 0.4 0.5 0.3 0.9 0.2 0.8 0.7 33.4 0.7 0.6 0.2 2.5 1.1 0.6 0.1 1.0 0.5 0.9 0.9 0.0 0.0 0.0 2.2 0.1 1.8 1.4 1.6 2.2 2.9 1.1 2.0 2.0 1.3 3.8 3.5 1.0 4.6 0.0 2.2 2.7 3.1 1.7 2.1 0.7 4.7 2.3 3.8 1.3 3.8 2.9 1.8 0.4 0.2 0.4 2.6 6.6 7.5 0.5 0.8 0.0 2.5 1.2 2.5 1.5 1.4 0.1 4.8 0.0 4.1 0.0 6.4 1.6 2.1 0.3 2.7 7.3 2.5 1.8 3.3 3.9 1.5 1.0 2.0 1.9 4.4 4.7 6.1 1.9 0.2 0.0 5.5 0.0 1.7 0.0 0.0 0.0 0.7 0.0 2.2 0.9 0.4 1.7 0.0 0.1 1.4 2.1 0.0 0.0 0.0 0.9 0.6 0.1 0.0 0.0 0.0 0.2 0.3 1.8 3.0 0.0 0.0 1.2 0.0 2.0 0.3 0.0 1.1 4.1 0.1 1.3 0.0 1.3 0.2 0.4 0.2 0.0 1.8 0.2 1.6 0.0 0.6 0.0 6.0 1.1 0.0 0.0 0.0 1.2 10.2 1.4 0.0 1.4 0.6 1.8 6.5 0.9 0.9 0.8 0.1 0.2 0.0 0.6 0.1 ASCC3 "ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH" ENSG00000112249 "Activating signal cointegrator 1 complex subunit 3" Q8N3C0 6 100508194-100881372 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031608, HPA031609, HPA031610" Enhanced Supported "Golgi apparatus,Cytosol" NA NA Cytosol "Golgi apparatus" "HPA031608: AB_10599970, HPA031609: AB_10600777, HPA031610: AB_10611526" "unprognostic (6.79e-2)" "unprognostic (1.46e-2)" "unprognostic (2.96e-3)" "unprognostic (1.12e-1)" "unprognostic (9.70e-3)" "unprognostic (4.56e-2)" "unprognostic (1.50e-1)" "unprognostic (5.14e-2)" "unprognostic (4.02e-1)" "unprognostic (3.34e-1)" "unprognostic (5.08e-3)" "unprognostic (1.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" 15.9 15.4 10.9 15.5 14.5 13.6 13.4 16.1 11.7 16.7 13.2 7.7 10.1 11.4 16.4 12.9 18.4 11.3 11.1 14.9 9.7 8.4 10.4 28.3 12.6 13.1 13.1 7.6 13.8 15.1 25.0 38.6 26.1 10.4 16.4 17.1 6.4 15.4 14.0 13.6 15.3 16.1 12.2 15.5 17.7 11.5 11.7 12.4 25.0 10.6 11.6 15.2 16.0 17.9 8.5 9.4 5.9 6.4 6.0 7.8 1.8 7.1 8.9 13.4 8.2 15.0 19.2 20.8 31.2 20.1 10.8 12.5 18.1 5.7 21.9 6.1 20.9 8.6 16.0 11.5 27.7 17.5 13.8 9.8 16.6 16.6 11.8 13.8 17.5 12.8 17.4 14.2 15.7 20.0 10.2 19.8 9.1 19.5 10.0 29.7 6.9 8.7 5.3 7.0 13.7 6.8 10.5 10.2 8.1 10.6 20.2 8.8 6.6 12.9 11.8 5.4 24.9 6.5 10.0 27.1 12.0 9.1 10.4 13.1 4.3 4.0 19.5 8.7 13.2 12.5 5.9 3.9 2.4 6.7 6.4 7.8 5.8 5.6 6.0 4.1 8.5 6.5 6.2 0.3 6.0 5.2 9.4 4.3 1.8 10.9 14.5 16.1 11.7 9.7 8.4 13.1 7.6 10.4 12.4 29.8 19.8 36.0 39.8 22.7 25.2 28.6 20.4 33.5 39.8 3.5 21.6 20.4 10.0 20.1 6.1 18.0 14.6 23.3 21.5 57.6 23.6 58.3 20.9 28.8 15.8 27.0 13.3 8.6 19.6 1.5 21.3 20.7 5.0 15.4 16.4 16.4 22.7 11.0 16.3 9.7 30.3 6.5 26.4 47.4 20.0 24.0 31.8 23.5 17.1 49.7 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503419 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.3;kidney: 33.2" "Group enriched" "Detected in many" 4 "Collecting duct cells: 24.4;Leydig cells: 46.1;Melanocytes: 43.9;Peritubular cells: 45.3;Proximal tubular cells: 65.3" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 8.3;ASC TERT1: 6.5;CACO-2: 5.5;HSkMC: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Approved Cytosol NA NA Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 10.9 4.1 14.5 1.8 37.6 1.7 3.3 3.0 19.4 6.2 3.6 35.2 3.1 9.7 4.1 5.5 4.5 5.0 3.3 2.2 21.9 11.0 33.2 12.6 3.2 1.3 50.2 11.3 2.9 1.0 0.9 0.9 3.1 18.9 4.0 4.6 2.6 1.9 4.8 9.3 4.6 13.3 2.9 22.4 4.6 3.9 5.6 51.3 0.0 1.8 1.1 0.8 4.5 3.5 1.7 1.2 3.6 0.7 1.6 1.3 0.2 0.4 0.2 0.9 0.7 8.3 6.5 0.5 0.4 0.3 0.3 0.3 5.5 0.3 1.1 0.3 1.0 0.5 0.5 0.5 0.3 0.4 2.9 0.3 0.5 0.9 0.4 0.9 0.7 0.8 11.7 0.6 0.7 0.2 0.4 0.1 0.7 0.6 2.0 0.4 0.4 0.4 1.0 0.8 0.4 0.5 0.4 0.5 0.9 0.4 1.7 0.7 0.5 1.6 0.6 1.3 0.8 0.6 0.3 0.6 1.0 0.7 0.7 0.4 1.2 0.6 0.7 0.4 0.6 0.8 3.4 0.7 0.8 1.2 0.6 1.0 1.1 1.0 0.9 0.5 1.7 1.2 1.3 3.6 1.6 0.7 1.2 0.5 0.2 14.5 37.6 3.0 19.4 21.9 11.0 50.2 11.3 18.9 51.3 8.9 1.0 0.0 1.2 4.6 0.4 0.8 5.1 0.0 1.2 24.4 0.0 0.0 6.6 0.0 2.8 0.5 1.0 0.0 0.2 0.1 7.4 0.3 0.0 10.2 0.2 7.9 2.4 4.9 1.5 0.5 46.1 0.8 43.9 0.0 0.1 3.4 0.0 0.0 45.3 65.3 0.5 0.0 4.2 4.8 0.6 1.5 0.1 0.0 1.2 1.7 ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085679-104115581 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 29.7;liver: 88.7" "Cell type enhanced" "Detected in many" 20 "Cardiomyocytes: 19.5;Hepatocytes: 83.1;Proximal tubular cells: 39.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "EFO-21: 2.6;HDLM-2: 3.0;HeLa: 2.5;HMC-1: 3.2;RPTEC TERT1: 1.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA069761 Enhanced NA NA "HPA069761: AB_2686191" "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" 0.7 0.5 0.4 0.4 0.5 0.0 2.1 0.4 0.5 1.5 2.3 0.5 0.4 0.5 1.6 1.0 10.2 2.0 0.8 29.7 0.4 0.0 9.8 88.7 1.3 0.9 0.4 0.4 4.9 0.4 0.7 0.4 0.8 0.7 0.4 0.8 1.2 0.8 0.4 0.4 5.2 0.8 1.1 0.4 0.4 1.6 0.9 0.4 0.4 1.3 0.6 1.7 0.5 2.8 0.2 0.0 1.0 0.1 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 1.8 0.8 2.6 0.0 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.1 0.7 1.0 0.0 0.7 0.6 1.9 1.9 1.5 1.2 0.0 0.1 0.8 0.2 1.2 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.5 0.4 0.0 0.4 0.4 0.7 0.4 6.0 1.7 0.0 0.1 1.5 1.0 19.5 2.5 2.7 0.0 0.0 0.0 0.1 3.3 0.0 0.4 0.3 8.4 0.0 0.2 0.1 0.6 0.2 0.0 83.1 0.2 4.8 1.7 3.7 0.6 0.0 0.0 0.0 0.0 0.0 10.8 0.2 0.3 5.9 1.1 39.3 0.2 0.0 0.0 0.4 0.7 8.0 0.5 0.0 3.0 2.5 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase like 1" Q7L266 11 62337448-62393412 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 52.4;cervix, uterine: 68.7;testis: 57.6" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 275.4;Late spermatids: 421.8;Spermatocytes: 320.2" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 51.4;eosinophil: 52.4" "Group enriched" "Detected in many" 4 "granulocytes: 52.4;monocytes: 14.2" "Cell line enhanced" "Detected in many" "EFO-21: 30.5;HAP1: 29.4;RPTEC TERT1: 26.0;SCLC-21H: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" NA NA Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: AB_2665720, HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favorable (6.14e-4)" "prognostic favorable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favorable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 3.6 2.6 27.8 3.8 37.0 7.1 4.6 12.3 22.3 68.7 7.9 9.9 2.0 4.1 15.3 7.9 1.4 36.8 9.5 1.7 19.5 19.0 23.8 2.4 6.6 3.3 30.8 11.8 1.6 5.1 1.5 5.7 2.3 16.4 8.6 9.9 4.9 6.4 4.8 2.3 1.2 3.1 3.0 9.6 2.4 5.6 57.6 11.3 2.8 3.7 0.0 3.0 2.9 1.0 0.5 8.2 52.4 14.2 2.5 0.7 4.9 0.8 6.7 7.4 9.6 0.0 0.0 5.8 0.8 0.3 1.3 1.2 11.0 3.0 0.7 30.5 0.1 3.3 0.6 29.4 0.3 1.5 1.1 12.1 0.4 9.1 8.0 0.2 8.1 11.0 0.3 0.1 0.6 0.1 0.4 13.8 16.7 8.2 7.6 0.3 12.8 21.8 5.4 10.1 4.6 5.3 8.9 4.4 4.1 26.0 2.1 40.1 5.7 5.7 9.9 4.9 8.0 5.3 4.1 0.7 0.1 5.6 0.4 3.3 11.7 11.1 1.0 0.3 4.2 3.4 51.4 14.2 52.4 0.6 10.3 0.4 0.5 0.2 0.7 8.2 0.4 0.5 0.7 3.3 2.5 7.2 1.4 0.1 4.9 27.8 37.0 12.3 22.3 19.5 19.0 30.8 11.8 16.4 11.3 6.0 26.7 10.4 1.9 3.1 21.7 1.6 53.5 1.4 3.4 21.0 31.4 1.4 112.7 25.5 275.4 23.3 4.1 0.0 19.3 1.8 3.8 54.4 76.5 2.6 22.5 15.9 45.3 31.9 9.1 421.8 8.1 27.7 1.7 0.0 35.8 78.6 8.8 5.8 6.7 99.6 37.4 12.9 2.3 320.2 48.6 1.1 0.7 6.9 26.0 5.3 ATAD1 FLJ14600 ENSG00000138138 "ATPase family, AAA domain containing 1" Q8NBU5 10 87751512-87841343 "Enzymes, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Early spermatids: 802.3;Late spermatids: 1314.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA "Nucleoli rim" Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favorable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 16.2 21.3 20.4 15.1 26.2 8.0 19.4 22.4 29.8 19.2 15.9 14.4 16.0 13.5 19.6 17.0 17.3 14.8 13.3 39.9 20.4 22.2 20.6 22.1 14.1 14.2 20.4 17.1 19.1 12.6 25.6 24.9 30.2 31.2 24.3 18.4 19.8 15.8 20.4 32.1 14.4 14.1 18.4 18.2 12.5 14.0 19.8 14.7 18.0 20.1 18.5 15.7 18.9 15.2 9.0 7.3 6.7 7.6 9.8 13.5 7.4 9.9 9.4 12.0 11.4 14.5 12.8 9.1 10.1 16.7 10.4 11.7 8.4 28.8 9.6 7.7 8.4 6.1 16.5 10.0 8.6 12.1 8.5 13.5 7.9 13.1 10.4 17.2 21.4 5.4 12.7 23.9 11.0 27.3 19.0 6.9 9.7 7.6 12.5 11.5 6.0 13.7 14.5 8.9 7.7 6.6 9.4 7.6 10.5 15.9 7.6 7.6 16.7 8.9 6.3 20.2 12.7 16.6 10.1 8.4 9.5 8.4 6.4 13.1 16.8 15.4 12.3 10.5 14.9 7.3 6.7 3.8 5.7 9.2 5.9 13.5 9.0 10.3 11.4 7.3 7.6 11.8 11.6 2.2 9.8 7.6 5.5 9.3 7.4 20.4 26.2 22.4 29.8 20.4 22.2 20.4 17.1 31.2 14.7 50.6 28.3 26.2 34.8 23.8 46.9 66.0 25.5 40.2 25.0 21.0 33.4 32.0 19.9 34.6 802.3 18.5 22.5 0.0 24.4 24.9 28.9 35.7 28.8 24.5 24.0 66.7 21.9 12.9 14.8 1314.1 33.1 25.4 30.4 15.4 23.3 53.3 31.9 26.4 44.2 23.7 46.8 58.2 38.7 58.1 20.9 26.3 73.9 29.9 22.1 44.1 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family, AAA domain containing 2" Q6PL18 8 123319850-123416350 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.8" "Cell type enhanced" "Detected in many" 7 "Spermatocytes: 74.6;Spermatogonia: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 75.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 4.1 4.9 4.6 12.6 9.2 22.8 7.2 5.6 6.9 14.0 8.6 1.5 13.4 5.3 4.7 5.0 10.7 4.7 3.5 13.7 4.2 6.3 2.2 10.1 9.8 13.7 4.0 4.3 9.9 3.9 3.5 18.7 5.2 4.0 11.4 7.5 2.4 6.8 15.4 13.8 7.2 6.6 5.5 4.1 8.8 6.9 20.2 3.4 53.8 4.8 6.3 12.7 9.9 5.9 4.3 2.3 7.2 2.8 4.0 7.4 1.8 25.5 9.9 14.2 4.8 2.5 3.2 6.2 20.0 6.9 17.3 19.3 7.5 11.1 16.7 6.1 6.3 6.8 12.2 18.9 6.4 27.8 23.2 10.1 30.0 10.7 15.2 1.0 10.9 14.9 1.0 1.0 16.4 5.4 3.7 5.2 9.8 14.0 17.0 12.8 26.4 31.4 8.2 2.5 19.3 9.9 16.4 16.9 9.0 6.1 11.7 18.2 7.9 29.0 75.6 5.1 6.0 15.4 10.4 3.2 13.1 18.1 10.3 24.0 5.5 9.8 15.5 8.6 18.4 10.2 7.2 1.5 5.4 2.9 1.3 4.0 4.3 4.2 4.8 2.3 2.8 2.8 3.0 0.4 4.0 2.8 0.3 7.4 1.8 4.6 9.2 5.6 6.9 4.2 6.3 4.0 4.3 4.0 3.4 6.0 8.3 14.2 19.9 14.1 2.5 22.9 2.5 5.3 11.4 3.5 3.9 8.2 1.7 2.4 46.2 6.7 2.2 23.3 1.9 21.2 7.3 19.9 13.9 14.0 9.7 1.6 1.2 9.2 11.1 17.9 6.9 6.6 1.7 5.4 4.4 5.2 2.7 3.5 13.1 0.9 2.1 0.0 8.6 74.6 90.7 10.7 11.3 15.3 12.8 24.8 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311817-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cytotrophoblasts: 144.4;Extravillous trophoblasts: 132.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3400000 Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 19.4 27.4 21.1 23.0 28.4 16.9 24.8 12.1 32.3 20.6 26.7 29.1 18.1 23.4 27.9 15.6 19.1 21.9 19.1 18.2 20.3 21.1 23.1 35.6 17.3 36.1 29.7 19.9 23.4 32.9 25.1 21.1 31.1 24.4 21.9 35.9 19.5 14.4 29.4 35.5 17.0 20.6 26.7 21.7 29.0 20.4 15.0 28.0 46.3 16.1 13.5 35.3 27.6 18.0 21.7 13.4 2.9 8.9 19.6 22.8 10.0 20.5 31.1 17.4 29.5 23.4 23.7 8.7 21.0 18.3 24.0 27.6 60.0 32.2 29.9 26.0 21.9 33.8 21.6 38.2 31.7 34.5 22.3 36.9 36.4 26.7 53.7 30.3 45.6 18.7 20.0 24.3 32.1 38.8 16.6 16.0 29.0 47.0 25.0 33.0 30.3 39.7 22.2 66.8 32.9 17.5 36.9 25.0 26.8 25.5 33.2 27.3 18.9 16.9 20.8 23.7 40.4 34.1 16.2 14.1 20.4 21.1 26.3 13.2 31.6 41.2 62.1 17.7 25.4 29.4 2.9 6.0 0.1 13.2 8.9 22.8 21.7 18.6 20.0 13.4 13.2 18.9 17.5 0.7 19.6 7.4 11.7 17.7 10.0 21.1 28.4 12.1 32.3 20.3 21.1 29.7 19.9 24.4 28.0 11.9 17.1 19.3 23.5 13.4 9.6 18.5 25.5 26.8 19.4 22.7 3.9 144.4 23.2 32.2 0.8 6.3 13.5 0.0 42.8 132.7 23.3 16.1 24.3 18.7 46.4 9.5 18.5 4.3 15.0 0.0 22.2 18.7 28.7 32.5 29.9 20.6 30.0 21.0 32.2 44.0 12.8 25.8 19.8 3.2 40.3 7.4 79.8 21.5 52.7 17.4 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677273-25865172 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 1: 29.8;Early spermatids: 17.6;granulocytes: 15.0;Late spermatids: 14.7;Melanocytes: 16.9;Peritubular cells: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 12 "dendritic cells: 3.0;NK-cells: 4.7;T-cells: 4.0" "Cell line enhanced" "Detected in some" "BJ: 13.0;fHDF/TERT166: 19.1;HMC-1: 12.7;RPTEC TERT1: 10.2;SK-MEL-30: 17.3" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 7.4 14.1 5.3 5.4 9.8 4.7 5.7 3.4 11.0 5.3 3.3 6.2 1.4 1.5 1.9 2.1 3.7 3.1 7.1 2.9 8.0 5.8 6.0 1.0 12.2 14.8 9.3 9.0 1.6 1.9 1.9 2.5 3.6 11.3 3.6 2.3 4.0 14.4 1.5 0.7 3.3 3.6 5.3 6.4 3.5 4.0 6.0 6.2 1.5 3.0 1.6 3.3 4.2 3.3 0.0 3.0 0.0 0.3 4.7 4.0 1.7 0.0 3.4 0.7 0.0 2.7 2.6 0.0 13.0 6.3 4.0 7.1 0.0 0.0 0.0 0.7 19.1 0.0 0.0 6.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.6 0.0 0.5 0.0 1.6 0.0 0.4 0.0 0.0 2.5 0.0 0.5 0.0 0.9 0.0 0.8 2.4 2.4 0.8 10.2 0.0 0.0 0.0 0.0 0.0 17.3 0.0 5.2 0.5 0.0 5.3 0.2 7.6 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.3 0.0 1.9 0.2 1.9 0.0 2.2 2.1 0.4 0.0 4.0 3.7 0.0 4.7 0.1 3.0 0.7 1.7 5.3 9.8 3.4 11.0 8.0 5.8 9.3 9.0 11.3 6.2 29.8 7.5 0.0 0.0 0.9 0.0 1.4 2.5 6.7 7.9 0.0 0.0 0.0 0.0 0.2 17.6 0.8 0.0 0.0 0.0 0.1 2.8 0.9 15.0 0.0 2.2 0.0 0.0 0.6 2.1 14.7 3.7 4.4 16.9 0.0 0.0 0.0 0.6 0.0 16.6 0.0 0.0 0.0 8.1 0.4 0.7 0.4 0.0 4.4 0.0 0.0 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.8;intestine: 35.4" "Cell type enhanced" "Detected in some" 11 "Enterocytes: 80.4;Mucus-secreting cells: 52.8;Paneth cells: 67.1;Undifferentiated cells: 77.9" "Group enriched" "Detected in many" 7 "colorectal cancer: 19.0;pancreatic cancer: 4.2;stomach cancer: 8.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "WM-115: 17.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034574 Uncertain NA NA "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.5 0.4 4.3 4.1 9.4 0.4 0.7 5.1 10.0 1.7 33.8 27.8 1.5 18.9 0.4 11.4 8.2 0.7 12.8 0.5 5.5 2.8 0.5 0.4 0.5 0.4 13.8 6.8 0.4 4.2 0.4 0.4 0.4 13.1 0.5 35.4 0.0 2.8 1.0 0.4 8.4 21.1 1.6 20.2 0.4 4.1 0.7 14.0 0.0 0.5 0.0 2.5 1.8 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 9.4 5.1 10.0 5.5 2.8 13.8 6.8 13.1 14.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 25.5 0.0 0.0 1.8 0.0 0.0 0.0 11.1 0.1 0.0 80.4 0.0 17.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.0 0.0 1.7 2.8 52.8 0.0 25.1 67.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 77.9 1.0 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485288-47593486 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 55.7" "Cell type enhanced" "Detected in many" 11 "Leydig cells: 57.5;Syncytiotrophoblasts: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "basophil: 31.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 31.5" "Cell line enhanced" "Detected in many" "HAP1: 24.4" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 8.1 9.7 7.6 6.8 8.0 1.4 6.9 3.9 7.5 10.2 7.4 5.2 10.4 4.5 12.9 10.1 15.2 6.7 8.6 7.4 7.3 4.0 14.5 5.8 9.4 6.7 7.0 4.8 10.0 6.2 16.9 18.6 55.7 8.1 8.1 4.5 7.7 7.5 11.5 2.8 14.8 6.0 11.4 8.9 12.7 7.6 3.9 7.3 3.6 10.7 5.4 9.2 9.9 13.1 3.6 1.8 31.5 2.9 1.0 0.9 0.6 1.4 1.0 2.3 1.6 6.7 7.3 0.4 10.4 12.6 5.0 9.0 5.4 9.0 4.6 3.9 16.8 8.5 2.7 24.4 8.7 7.7 1.8 1.9 3.7 1.7 0.3 6.0 1.1 2.3 6.3 6.7 9.8 6.5 16.5 8.4 2.3 0.0 2.5 13.6 0.5 2.4 0.7 0.8 0.0 1.3 2.8 5.3 0.0 9.1 1.8 1.5 2.9 4.8 1.2 3.1 5.4 2.2 1.2 12.7 12.4 2.5 1.1 4.5 1.1 0.8 0.0 6.1 6.9 3.9 31.5 1.4 0.1 0.6 2.3 0.9 1.3 0.2 0.3 1.8 3.6 0.0 0.4 0.7 1.0 2.9 1.1 0.3 0.6 7.6 8.0 3.9 7.5 7.3 4.0 7.0 4.8 8.1 7.3 8.9 6.9 15.0 7.9 17.1 10.9 3.6 0.0 2.7 2.3 15.7 29.5 27.1 1.7 4.3 1.6 14.0 1.6 0.0 4.1 7.4 11.8 5.8 2.3 4.9 11.7 12.7 9.2 17.8 16.1 0.6 57.5 9.1 6.8 7.2 4.3 28.8 2.7 2.5 23.7 9.1 8.9 25.8 9.8 0.4 2.7 23.6 147.8 11.5 3.7 6.5 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 202.5;Alveolar cells type 2: 171.3;Cone photoreceptor cells: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Enhanced Vesicles NA NA Vesicles "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 11.1 11.5 7.2 8.3 16.4 15.7 7.9 5.0 12.5 13.6 5.8 24.4 8.7 9.5 13.7 9.2 8.5 10.8 14.6 19.6 7.2 5.4 12.9 12.3 36.9 7.5 17.7 6.9 8.6 13.2 36.1 17.8 11.2 12.8 5.0 3.6 10.0 12.0 9.0 11.2 11.4 8.7 9.1 12.5 10.2 6.1 9.7 16.2 2.1 16.4 6.4 6.0 5.7 11.3 4.2 1.1 6.4 3.1 0.0 1.0 0.6 14.0 7.2 9.1 10.7 4.6 6.3 16.2 6.7 3.9 5.7 4.7 22.6 16.3 7.1 8.2 5.6 7.4 12.0 8.2 5.5 5.6 7.1 7.7 8.2 6.0 11.7 7.3 15.3 13.4 4.2 4.3 6.9 4.2 4.6 15.0 6.5 5.6 1.2 4.0 5.3 6.9 9.7 3.9 16.1 5.1 6.1 3.7 4.0 31.3 3.3 14.6 4.0 6.5 8.5 5.6 12.4 3.2 20.5 9.8 0.0 12.5 7.4 5.0 3.9 7.5 3.0 2.5 14.5 6.3 0.0 2.3 3.1 1.0 3.1 0.6 1.3 0.6 0.5 1.1 4.2 0.7 0.4 6.4 0.0 2.7 1.1 0.1 0.6 7.2 16.4 5.0 12.5 7.2 5.4 17.7 6.9 12.8 16.2 202.5 171.3 5.6 2.8 9.6 29.4 38.0 35.7 16.0 45.5 15.7 221.9 0.6 5.0 31.2 0.7 19.8 4.2 0.0 10.0 26.5 10.6 5.3 11.5 13.2 17.6 12.7 11.5 24.5 33.5 1.4 10.3 21.3 10.1 7.2 3.3 10.4 18.9 5.8 4.6 15.8 44.2 0.0 5.1 3.9 9.0 8.4 7.2 5.7 5.2 3.7 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793500-182921635 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 16.8 7.9 7.7 19.7 9.8 35.4 17.0 18.4 9.4 20.5 21.6 8.9 14.3 13.6 15.0 11.7 37.3 11.8 12.7 21.1 6.9 5.9 13.7 14.3 19.4 20.3 10.3 5.7 15.2 14.6 21.0 26.0 8.0 8.3 16.8 16.9 9.8 19.7 13.8 13.1 21.8 22.8 16.5 11.3 23.4 27.6 22.8 8.9 49.0 10.8 20.4 21.9 22.7 25.5 3.6 4.2 7.5 1.8 3.0 3.4 1.3 22.7 3.3 7.2 10.0 15.3 16.8 6.6 10.5 14.5 8.2 9.6 8.1 11.8 10.6 18.0 15.1 17.1 13.8 8.5 10.8 14.3 23.4 6.8 25.4 4.4 1.7 8.9 20.0 16.3 11.3 12.3 9.2 13.3 12.1 12.8 16.9 9.0 32.9 13.2 7.7 16.6 6.4 5.1 12.9 6.4 6.9 21.0 12.7 9.9 19.1 4.3 7.7 29.3 3.7 12.8 6.8 4.1 14.9 12.6 12.5 13.5 10.7 18.2 45.0 40.2 19.8 8.6 8.6 7.3 7.5 1.7 7.2 3.1 1.8 3.0 3.6 2.7 3.1 1.9 2.4 2.3 3.4 6.8 3.0 1.7 4.2 2.0 1.3 7.7 9.8 18.4 9.4 6.9 5.9 10.3 5.7 8.3 8.9 14.9 10.4 9.7 20.0 30.5 11.4 15.9 17.8 6.7 11.4 19.2 13.7 9.6 0.0 10.9 27.7 14.5 26.1 46.7 14.4 3.2 14.9 34.3 10.5 13.6 9.2 36.5 6.4 14.1 17.8 19.9 17.8 17.7 13.5 5.4 27.5 8.1 20.8 27.1 19.8 6.2 28.3 19.4 16.5 15.4 10.7 39.0 8.0 24.9 20.4 44.2 ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 47.7;Spermatogonia: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" 12.8 7.0 4.8 7.6 10.6 4.6 9.6 8.0 5.8 13.1 8.8 5.3 30.2 4.8 12.0 9.5 7.3 9.1 7.4 5.2 6.7 4.5 10.8 41.4 6.7 11.2 9.6 3.2 13.1 4.6 6.8 4.2 4.6 9.5 11.5 6.4 10.7 5.8 21.4 6.6 5.6 7.8 11.3 6.3 14.4 7.1 7.9 9.7 14.9 6.1 4.0 7.4 12.7 12.2 2.8 2.1 5.1 1.7 3.5 2.5 0.5 9.4 4.0 8.4 13.6 12.5 17.0 10.6 11.4 15.3 9.2 12.8 3.6 7.7 13.6 25.7 16.1 6.1 8.0 20.1 5.2 14.5 12.4 11.8 6.9 8.9 7.0 13.9 11.9 4.4 11.2 3.5 10.0 8.6 10.3 15.9 10.6 7.7 10.5 12.1 5.1 10.9 8.1 14.1 0.0 7.7 11.0 9.0 11.3 7.8 15.8 6.5 10.8 4.5 0.5 5.9 8.2 3.4 6.6 17.8 12.6 4.2 15.2 15.4 3.0 2.9 10.8 5.8 15.0 6.3 5.1 1.5 0.4 1.2 1.0 2.5 2.8 1.4 1.1 1.2 2.7 1.4 2.2 2.8 3.5 1.7 2.1 1.0 0.5 4.8 10.6 8.0 5.8 6.7 4.5 9.6 3.2 9.5 9.7 14.9 9.6 13.0 14.5 12.9 1.6 3.9 2.5 5.3 11.4 10.4 0.0 1.7 1.7 4.8 9.9 20.3 4.5 0.0 8.5 10.5 16.6 10.9 9.2 43.9 7.9 0.0 8.7 28.8 29.5 8.5 13.3 8.6 10.1 47.7 6.0 2.8 6.4 5.8 14.5 8.2 3.4 0.0 20.6 23.2 49.4 11.8 5.6 8.7 4.5 13.6 ATP12A "#945, 2, ATP1AL1, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680411-24712493 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 12.3;lymphoid tissue: 38.4" "Group enriched" "Detected in some" 7 "Ciliated cells: 5.3;Club cells: 18.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Cell type enriched" "Detected in single" 5 "T-reg: 1.7" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enriched" "Detected in some" 8 "SuSa: 11.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Plasma membrane, Cytosol" "Actin filaments" "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.8 0.2 1.3 0.4 0.1 0.0 0.0 0.0 0.2 0.2 12.3 0.1 0.0 0.1 0.3 0.2 8.8 0.1 6.1 0.0 0.1 0.0 0.1 1.0 0.0 0.2 5.8 0.4 0.3 2.2 0.0 0.4 0.0 0.1 9.8 0.1 0.0 0.1 0.1 0.1 1.0 0.0 1.2 0.2 2.9 38.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.1 0.2 1.3 0.3 0.2 0.1 0.0 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 5.3 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.2 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 195.4;parathyroid gland: 194.4" "Cell type enhanced" "Detected in all" 5 "Enterocytes: 917.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 254.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 380000 "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" 17.4 25.6 22.4 16.2 40.3 10.5 26.9 74.2 67.4 17.8 121.9 14.2 56.1 92.3 13.1 38.3 34.9 17.7 65.8 41.1 26.1 18.7 162.7 34.6 35.1 9.6 19.2 27.6 17.4 78.6 194.4 25.0 19.2 34.1 22.1 65.7 24.1 84.4 53.7 19.0 40.5 195.4 17.7 20.7 13.7 25.0 17.0 13.9 9.1 101.2 13.7 16.2 14.2 23.1 10.3 22.0 6.4 29.7 10.4 30.2 17.2 33.7 12.4 12.9 6.5 26.0 25.3 66.6 20.2 40.3 24.9 35.4 49.8 24.2 26.7 28.6 23.9 25.3 44.1 25.5 42.6 36.3 9.8 28.3 15.5 23.5 42.0 19.9 38.9 21.9 28.1 71.5 29.0 38.3 35.2 30.5 16.3 25.6 25.8 22.0 67.0 15.7 14.1 30.4 53.6 25.0 15.2 30.3 23.6 90.1 34.8 12.7 11.2 31.4 59.6 254.2 33.2 15.7 22.6 26.9 14.2 19.9 36.7 40.9 12.5 9.7 20.5 43.6 22.5 83.4 6.4 13.3 6.1 23.2 20.9 24.8 10.3 26.4 24.9 22.0 5.3 30.2 22.0 1.6 10.4 29.7 11.1 20.3 17.2 22.4 40.3 74.2 67.4 26.1 18.7 19.2 27.6 34.1 13.9 256.1 246.7 58.7 265.3 245.9 76.0 62.7 540.1 113.8 203.6 731.0 375.0 70.1 316.7 432.8 25.0 117.9 917.6 93.5 278.3 130.8 110.9 297.5 43.8 66.4 114.8 96.9 169.4 90.9 77.6 11.5 109.0 130.5 197.4 47.7 304.0 513.0 192.4 264.8 94.7 289.6 141.6 32.3 179.2 17.9 27.5 235.0 56.5 95.6 365.5 236.0 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 109.8;skeletal muscle: 305.8" "Cell type enhanced" "Detected in some" 18 "Cardiomyocytes: 142.4;Muller glia cells: 63.9;Peritubular cells: 37.1;Sertoli cells: 84.1;Smooth muscle cells: 32.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 32.9;HHSteC: 9.6;RH-30: 10.7;U-87 MG: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 12.6 3.9 61.4 2.8 80.1 2.3 6.5 30.4 109.8 4.7 6.6 27.4 2.4 3.7 4.2 7.4 15.3 6.0 5.3 35.4 42.2 27.0 3.3 2.5 3.8 2.4 45.6 37.9 9.9 2.6 2.4 4.6 3.6 58.0 13.8 5.6 12.5 3.1 14.2 305.8 2.8 4.4 5.4 51.5 2.7 2.8 3.9 28.3 0.0 2.6 17.7 2.5 5.5 1.3 0.6 1.4 1.7 0.4 0.6 0.5 0.3 0.0 0.0 32.9 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 2.9 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 1.3 0.4 0.3 0.3 0.3 0.2 0.4 0.3 0.2 0.7 0.6 0.3 0.5 1.7 0.6 0.2 1.4 0.2 0.3 61.4 80.1 30.4 52.0 42.2 27.0 45.6 37.9 58.0 28.3 0.0 0.0 0.0 0.8 0.5 0.7 142.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.0 0.0 1.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 26.7 0.0 0.0 0.0 0.0 63.9 0.0 0.0 37.1 0.0 1.9 84.1 32.5 0.3 0.2 0.5 0.1 0.0 0.0 0.5 ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Deafness, Disease mutation, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 146.4;heart muscle: 78.3" "Cell type enhanced" "Detected in some" 17 "Bipolar cells: 387.3;Cone photoreceptor cells: 161.0;Horizontal cells: 201.8;Late spermatids: 93.3;Rod photoreceptor cells: 178.0" "Group enriched" "Detected in many" 6 "glioma: 21.6;testis cancer: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2;memory CD8 T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Cell line enhanced" "Detected in many" "Daudi: 20.7;JURKAT: 13.5;Karpas-707: 13.2;REH: 13.0;SCLC-21H: 49.1;SH-SY5Y: 21.1" "CAB033630, HPA045367, HPA056446" Enhanced Approved NA NA "CAB033630: AB_781528, HPA045367: AB_2679297, HPA056446: AB_2683136" "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavorable (3.44e-4)" "prognostic favorable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavorable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" 1.9 12.8 34.0 2.5 30.8 2.1 1.8 42.8 146.4 1.8 2.4 4.8 0.0 2.4 1.8 1.8 2.0 1.8 1.9 78.3 48.3 54.6 1.8 1.8 1.9 2.3 39.9 42.6 1.8 2.3 1.8 3.0 1.8 94.4 1.8 2.3 17.3 2.2 1.8 1.8 2.0 2.7 2.2 18.5 2.1 2.0 18.6 6.9 0.0 1.8 0.0 2.1 1.9 0.1 0.3 0.1 0.0 0.0 0.1 2.2 0.3 0.0 0.8 0.3 8.7 0.0 0.0 0.0 0.1 0.0 0.6 0.6 0.3 1.6 20.7 0.9 0.1 2.0 0.2 6.1 0.0 0.2 3.9 1.1 1.8 0.0 0.1 0.0 0.0 6.8 0.0 0.0 0.0 0.1 0.1 0.0 13.5 0.0 13.2 0.1 0.3 3.7 0.0 1.1 2.9 5.3 13.0 7.1 0.6 0.0 0.2 49.1 21.1 0.1 1.6 0.0 0.0 1.3 0.9 0.0 1.1 1.1 0.0 0.4 1.3 0.9 4.7 1.9 7.2 0.2 0.0 0.0 0.0 2.2 0.0 0.2 0.3 0.6 1.7 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.1 0.7 0.3 34.0 30.8 42.8 66.6 48.3 54.6 39.9 42.6 94.4 6.9 0.0 7.9 0.5 0.3 0.2 387.3 15.7 0.0 0.0 0.0 0.0 161.0 0.0 0.0 0.0 33.6 0.3 0.0 0.0 0.0 0.1 0.6 0.2 1.1 0.0 0.2 201.8 0.0 0.0 0.0 93.3 1.7 0.2 0.0 0.0 0.0 25.9 0.0 0.0 0.4 0.0 178.0 0.0 0.0 21.3 3.2 0.3 0.2 1.9 0.0 0.4 ATP1A4 ATP1AL2 ENSG00000132681 "ATPase Na+/K+ transporting subunit alpha 4" Q13733 1 160151570-160186977 "Enzymes, Predicted membrane proteins" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 13.1;seminal vesicle: 19.0;testis: 35.8" "Cell type enhanced" "Detected in some" 20 "Cytotrophoblasts: 20.6;Early spermatids: 67.0;Syncytiotrophoblasts: 31.9" "Group enriched" "Detected in some" 8 "breast cancer: 0.8;urothelial cancer: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "BEWO: 10.8;HDLM-2: 26.8;RT4: 32.4" "Not detected" "Not detected" NA NA "unprognostic (1.33e-1)" "unprognostic (4.01e-3)" "unprognostic (2.20e-1)" "unprognostic (1.94e-1)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (1.22e-1)" "unprognostic (7.48e-3)" "unprognostic (2.45e-1)" "unprognostic (8.77e-3)" "unprognostic (1.98e-2)" "unprognostic (3.17e-2)" "unprognostic (2.43e-3)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (4.09e-2)" "prognostic favorable (2.20e-4)" 0.4 0.3 0.4 0.8 0.3 0.0 2.2 0.4 0.3 0.3 0.3 0.0 11.2 0.0 0.2 0.3 0.3 0.3 0.8 0.3 0.3 0.3 0.2 0.2 0.3 3.8 0.3 0.0 0.2 0.2 0.0 0.3 13.1 0.0 0.6 0.0 0.4 1.2 19.0 3.2 0.3 0.5 1.6 0.3 1.1 0.3 35.8 0.0 0.9 0.2 0.2 1.6 8.9 5.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.0 1.1 0.0 5.5 0.2 0.0 0.8 0.0 0.0 0.0 1.8 0.0 20.6 0.0 0.0 67.0 0.0 0.0 0.0 0.0 11.9 0.4 0.7 1.1 0.0 2.4 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.2 0.2 0.0 31.9 0.0 0.0 11.2 ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904509 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "skeletal muscle: 456.3;tongue: 209.0" "Cell type enhanced" "Detected in some" 20 "Cone photoreceptor cells: 13.7;Late spermatids: 2.9;Rod photoreceptor cells: 4.6;Spermatogonia: 3.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 19.8" "Region enriched" "Detected in single" 8 "thalamus: 14.3" "Not detected" "Not detected" "CAB002310, CAB032706" Enhanced Approved "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "CAB002310: AB_564139, CAB032706: AB_2061286" "unprognostic (2.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.23e-5)" "unprognostic (5.35e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.87e-1)" "unprognostic (5.22e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-4)" "unprognostic (1.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-2)" 7.6 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.1 1.1 5.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.6 0.1 12.6 7.0 0.3 456.3 0.2 0.2 0.1 0.1 0.1 0.1 0.9 0.0 0.0 4.2 209.0 6.5 0.2 0.1 1.6 3.1 0.7 0.2 4.7 1.5 0.6 4.8 5.2 9.6 5.8 0.4 1.6 8.9 2.3 1.3 0.4 0.4 2.9 4.4 7.6 2.7 0.4 3.2 5.1 2.4 0.1 0.7 3.8 19.8 2.7 11.8 9.0 0.2 1.1 2.6 4.1 1.1 0.6 0.5 4.9 0.2 14.3 5.2 6.5 0.3 9.7 10.9 6.1 9.7 1.8 7.4 16.9 6.8 5.7 0.0 0.6 6.2 4.9 3.3 4.5 3.4 3.7 3.4 2.7 2.0 3.0 6.3 5.6 2.8 9.5 5.8 7.4 5.9 15.0 2.9 0.0 0.1 0.7 1.0 0.0 1.3 1.6 1.1 1.0 0.0 0.8 1.4 1.3 0.0 4.7 0.2 3.1 1.5 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.3 0.0 0.0 0.0 0.0 13.7 0.3 0.0 0.1 1.0 0.0 0.5 0.0 0.2 0.1 0.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.0 0.1 0.5 0.2 0.3 0.0 0.0 4.6 0.0 0.0 1.8 3.0 0.1 0.6 0.0 0.6 0.0 ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 188.3;skeletal muscle: 319.7" "Cell type enriched" "Detected in all" 12 "Cardiomyocytes: 1592.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062605 Enhanced NA NA 38000000 "HPA062605: AB_2684805" "unprognostic (4.81e-2)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.41e-3)" "unprognostic (2.50e-1)" "unprognostic (3.98e-3)" "unprognostic (1.91e-2)" "unprognostic (6.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-3)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (9.93e-2)" 8.4 8.8 7.3 8.5 14.5 5.7 7.5 7.4 20.8 8.2 9.6 8.0 8.3 7.3 9.4 10.3 24.1 9.4 9.3 188.3 10.1 5.0 6.7 11.8 8.9 5.6 5.6 13.1 8.5 7.6 8.7 6.1 8.1 10.2 13.0 11.2 22.3 18.3 9.6 319.7 9.3 9.3 14.3 7.4 5.4 7.9 11.9 7.1 3.1 12.6 51.3 12.7 13.4 11.4 0.8 2.2 0.2 4.4 1.7 1.7 0.7 35.5 70.9 35.9 28.8 23.9 30.6 51.8 44.3 55.8 45.0 30.3 51.2 37.9 43.9 37.5 42.1 34.0 52.0 59.4 70.0 51.2 36.3 29.7 38.3 28.4 29.9 40.6 43.7 37.1 32.1 49.4 57.1 55.4 43.3 34.7 23.0 44.6 21.5 36.6 34.1 23.6 27.1 40.9 36.5 35.9 24.9 32.3 36.2 22.2 73.4 38.0 28.5 55.8 45.8 25.9 34.2 61.6 23.6 37.2 41.7 22.4 27.7 33.8 44.2 53.8 49.2 38.0 18.9 47.2 0.0 1.9 0.0 1.7 4.4 0.9 0.7 1.3 1.1 1.9 0.8 1.3 1.2 0.2 1.7 2.3 2.2 1.2 0.7 7.3 14.5 7.4 20.8 10.1 5.0 5.6 13.1 10.2 7.1 41.7 53.9 23.1 78.3 101.7 60.4 1592.4 45.9 96.4 83.0 48.8 60.9 28.0 1.7 40.8 10.7 37.6 123.8 23.3 60.6 31.5 51.2 89.3 43.9 110.5 56.0 79.4 131.8 41.1 50.1 9.0 28.1 40.7 64.1 19.0 80.6 24.0 82.4 70.2 78.1 23.9 39.0 51.8 126.0 61.6 55.1 95.2 25.6 17.0 66.5 93.6 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.4;salivary gland: 88.1" "Cell type enhanced" "Detected in many" 10 "Enterocytes: 61.6;Intestinal endocrine cells: 94.0;Mucus-secreting cells: 112.7;Paneth cells: 46.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebellum: 10.9;midbrain: 4.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 39.3;HMC-1: 58.2;JURKAT: 32.7;MOLT-4: 52.0;SK-BR-3: 42.3" "Region enriched" "Detected in some" 15 "cerebellum: 75.4" "Low region specificity" "Detected in many" "HPA007180, CAB010882" Approved NA NA 100000000 "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 2.1 4.9 0.9 36.9 1.6 24.3 2.7 10.9 1.7 2.3 15.4 1.8 48.8 8.1 3.4 2.8 4.5 2.2 16.0 2.6 0.9 0.7 3.4 1.6 7.8 25.6 4.1 1.4 2.1 20.2 0.0 0.8 1.7 1.4 7.4 9.0 8.7 88.1 47.3 0.9 9.4 26.1 3.0 1.0 36.4 25.5 1.6 1.2 82.4 4.2 6.0 47.5 5.4 2.6 8.3 10.8 21.1 1.0 2.5 7.8 3.9 0.0 1.6 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.3 39.3 2.4 0.1 0.0 0.1 0.6 0.0 0.0 4.8 0.4 20.5 1.2 0.0 0.3 22.3 58.2 0.0 0.0 0.1 0.0 0.0 0.0 32.7 4.1 25.4 0.0 24.4 52.0 24.0 0.2 11.1 0.3 5.7 0.0 9.0 0.0 0.7 2.5 0.7 0.3 42.3 0.0 0.2 2.6 5.5 0.1 0.0 0.4 0.1 0.0 9.4 2.8 13.8 0.5 15.9 0.0 9.1 1.0 21.1 7.8 0.6 6.1 6.9 4.8 7.2 1.0 8.3 3.6 4.4 9.0 2.5 0.3 10.8 4.2 3.9 0.9 1.6 10.9 1.7 0.9 0.7 4.1 1.4 1.4 1.2 0.0 3.4 44.0 0.4 0.8 0.0 2.2 5.1 1.4 2.3 22.7 0.0 0.2 0.0 1.7 0.1 3.6 61.6 0.0 10.8 0.2 2.0 6.5 33.4 0.8 2.8 0.0 94.0 7.4 3.5 0.0 0.0 2.6 11.8 0.0 112.7 0.2 17.0 46.0 0.7 0.2 0.1 0.0 3.1 0.0 0.7 0.3 0.0 20.8 41.2 2.5 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 53.8" "Cell type enhanced" "Detected in many" 4 "Bipolar cells: 311.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 59.7;LHCN-M2: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 8.7 5.1 23.4 12.5 53.8 40.5 8.8 30.9 44.1 9.0 14.0 4.1 4.0 17.8 8.2 5.8 6.5 8.4 11.3 5.2 29.0 11.8 7.4 10.0 9.2 11.8 7.8 31.5 7.6 7.4 13.7 8.7 11.7 9.2 6.4 14.8 2.9 5.6 6.9 10.9 11.3 12.8 8.7 6.1 12.7 12.4 9.8 16.4 5.7 6.3 6.0 12.3 9.9 7.4 27.1 16.2 41.5 25.6 8.4 16.3 6.2 4.2 21.5 8.5 4.1 12.4 19.7 3.9 13.0 42.9 12.6 20.2 8.6 3.9 8.4 0.9 18.1 14.6 3.8 7.4 3.6 35.5 2.9 8.7 3.0 7.6 7.5 40.3 12.5 5.0 16.3 6.9 39.5 59.7 14.9 3.2 3.2 4.9 3.1 92.7 6.7 3.9 5.4 6.6 5.9 10.3 5.6 27.4 3.5 12.0 19.8 8.0 4.4 15.1 4.3 3.6 18.0 6.3 1.4 2.2 34.5 5.6 12.6 14.2 2.3 3.6 9.0 15.6 3.5 7.6 2.7 13.0 6.7 7.1 13.6 9.0 27.1 12.4 9.0 16.2 27.0 4.6 5.7 41.5 8.4 25.6 2.9 16.3 6.2 23.4 53.8 30.9 44.1 29.0 11.8 7.8 31.5 9.2 16.4 41.7 42.4 79.2 52.7 179.2 311.6 18.9 45.9 29.4 36.4 50.6 145.3 117.8 1.7 21.2 1.8 49.1 113.3 0.0 24.6 36.9 79.9 37.8 30.1 35.8 157.7 286.0 87.9 47.3 100.2 6.0 27.0 213.2 52.3 116.4 24.1 78.6 21.7 48.2 30.1 23.1 99.9 32.3 51.5 12.9 122.1 178.9 191.3 55.4 45.3 59.3 ATP2B2 PMCA2 ENSG00000157087 "ATPase plasma membrane Ca2+ transporting 2" Q01814 3 10324023-10708007 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 55.1;liver: 15.2;salivary gland: 28.6;skeletal muscle: 30.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 85.3;Hepatocytes: 27.0;Horizontal cells: 98.5" "Cancer enhanced" "Detected in some" "liver cancer: 7.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 5.4;RPMI-8226: 15.3;SCLC-21H: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005606 Enhanced NA NA "CAB005606: AB_2243199" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (6.84e-2)" "unprognostic (1.59e-2)" "unprognostic (3.59e-1)" "unprognostic (3.62e-1)" "unprognostic (4.09e-2)" "unprognostic (4.65e-1)" "unprognostic (5.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.32e-4)" "unprognostic (2.70e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "unprognostic (1.33e-2)" "unprognostic (8.34e-2)" "unprognostic (7.95e-3)" 1.0 1.5 7.6 1.0 23.0 0.9 1.0 39.9 55.1 3.0 1.0 2.4 0.0 1.0 3.2 1.1 1.1 4.3 1.0 1.0 10.0 6.2 1.1 15.2 1.0 1.0 7.9 14.7 1.0 1.1 0.9 1.7 0.9 15.5 1.0 1.0 0.7 28.6 0.9 30.3 1.3 1.0 2.3 2.5 1.0 1.0 1.5 4.2 0.0 0.9 0.0 1.0 0.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 15.3 0.0 0.0 5.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 7.6 23.0 39.9 55.1 10.0 6.2 7.9 14.7 15.5 4.2 0.0 0.0 0.0 0.0 0.5 85.3 7.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 27.0 0.0 98.5 0.0 0.6 1.0 5.7 0.0 0.0 3.3 0.0 0.0 14.5 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 18.6;brain: 23.2" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.0;Extravillous trophoblasts: 8.3;Rod photoreceptor cells: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 14.6;SH-SY5Y: 4.3;THP-1: 3.5;U-937: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced Supported NA NA "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" 0.8 18.6 5.4 0.9 11.3 0.8 0.8 16.1 23.2 0.8 0.9 3.9 0.0 0.9 0.9 2.6 0.8 3.1 0.8 0.8 7.8 5.5 1.0 0.8 0.8 0.8 4.3 11.5 0.8 0.9 0.8 1.2 1.7 13.6 0.8 0.8 1.4 1.3 1.3 0.8 0.9 0.9 0.9 1.4 0.8 0.8 1.1 0.9 0.0 0.8 0.0 0.8 0.8 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 4.3 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 11.3 16.1 20.7 7.8 5.5 4.3 11.5 13.6 0.9 0.0 0.0 0.0 0.0 0.0 5.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626561-203744081 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Muller glia cells: 153.7;Suprabasal keratinocytes: 132.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 59.5;fHDF/TERT166: 45.1;SuSa: 49.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA 21000 "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 23.0 14.0 24.8 10.8 14.2 5.9 11.6 9.4 23.6 32.6 44.2 7.5 12.9 5.3 69.6 13.1 20.4 27.0 13.9 24.0 13.1 8.7 5.0 14.2 16.1 5.3 6.4 19.2 21.9 6.4 8.0 4.8 16.2 9.3 17.0 13.4 11.6 7.5 31.5 5.4 22.0 13.2 74.2 5.7 4.8 16.4 13.1 7.5 9.0 8.3 8.4 7.7 32.8 14.2 1.0 4.2 4.5 2.2 4.2 10.4 2.6 9.2 1.7 3.4 3.2 26.0 38.8 18.0 41.8 59.5 7.1 6.1 0.8 4.7 2.1 6.1 45.1 9.5 9.0 4.9 5.8 7.5 26.5 1.7 6.2 8.3 0.5 9.3 8.8 11.0 28.1 5.7 22.8 3.5 17.3 13.5 12.3 2.7 4.2 5.2 0.5 8.9 2.9 2.0 1.7 5.2 4.7 2.5 3.3 2.4 0.8 1.0 1.4 14.7 2.2 6.6 49.6 1.9 4.3 11.8 17.3 2.5 29.0 10.0 2.8 4.2 1.1 17.3 6.4 5.1 3.0 2.2 0.0 10.4 1.5 7.9 1.0 6.6 8.3 2.4 0.3 1.6 4.2 4.5 4.2 2.2 4.2 6.3 2.6 24.8 14.2 9.4 23.6 13.1 8.7 6.4 19.2 9.3 7.5 83.4 62.7 10.4 15.6 86.3 2.8 64.1 7.6 34.8 40.9 17.4 2.0 22.3 0.0 31.1 4.3 39.1 3.9 23.3 13.2 13.3 48.3 9.5 9.3 15.7 31.0 111.2 23.0 54.6 14.6 1.3 40.6 13.2 25.3 7.2 1.9 153.7 25.2 11.9 35.7 5.0 6.9 19.4 82.4 22.3 2.1 132.0 21.7 45.7 2.6 43.3 ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" NA NA 28000 "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: AB_2686169" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favorable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" 18.6 22.9 29.6 14.5 29.4 20.4 36.8 24.5 34.6 22.2 21.6 23.0 14.3 14.4 19.3 18.0 16.9 23.4 16.8 19.2 31.6 32.3 28.0 17.1 30.7 16.0 31.8 25.4 18.5 14.6 47.6 31.0 19.6 26.7 54.0 22.4 18.1 20.3 16.6 16.1 21.3 16.0 19.2 44.6 11.1 18.7 16.0 25.6 20.5 21.7 15.5 15.4 19.3 29.6 4.7 7.6 21.6 7.0 8.7 7.2 4.9 36.6 14.4 14.5 13.9 40.6 32.9 15.6 40.1 53.5 20.2 25.5 23.4 30.3 13.3 27.9 37.9 28.1 43.7 27.2 22.1 29.6 28.7 9.8 35.4 15.3 10.8 25.9 14.1 43.2 25.8 22.3 21.2 24.1 36.9 21.3 16.9 10.2 24.3 24.8 16.3 13.8 11.3 16.4 20.0 15.7 10.0 14.4 20.9 37.2 24.7 22.4 13.4 34.5 10.8 20.2 21.6 16.0 11.6 29.1 21.5 12.0 27.6 18.4 15.7 19.0 19.7 22.2 10.6 17.9 21.6 7.0 12.1 6.3 6.0 5.9 4.7 6.2 5.6 7.6 2.9 4.3 4.3 3.5 8.7 7.0 6.6 7.2 4.9 29.6 29.4 24.5 34.6 31.6 32.3 31.8 25.4 26.7 25.6 35.7 45.2 11.3 32.9 34.9 26.4 27.0 40.8 24.1 23.9 43.6 19.6 13.5 5.0 32.7 12.6 25.1 15.9 0.0 33.1 24.1 29.4 68.4 27.7 24.6 26.6 77.9 34.2 22.7 18.3 14.0 15.0 28.6 20.3 19.8 31.3 22.6 44.4 25.9 13.8 18.6 33.2 6.5 24.2 15.2 14.9 46.2 14.8 13.8 29.3 33.5 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.0;salivary gland: 35.8" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 2: 42.2;Ciliated cells: 72.3;Mucus-secreting cells: 62.9;Undifferentiated cells: 69.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 24 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "MCF7: 14.5;OE19: 26.0;RT4: 11.4;SK-BR-3: 20.2;T-47d: 6.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.3 0.0 2.1 8.0 1.5 6.1 2.5 0.2 2.0 3.5 23.0 0.5 1.9 16.3 1.8 1.9 2.7 4.0 18.8 0.4 1.8 1.9 2.6 0.2 21.9 0.2 1.3 0.7 1.3 0.5 0.0 2.9 4.8 0.7 7.9 21.9 1.0 35.8 0.2 0.9 15.2 14.5 0.5 0.6 0.2 3.4 0.4 0.4 0.3 8.2 2.2 8.1 4.8 7.8 0.0 0.0 2.7 0.0 0.0 0.1 0.0 3.6 0.2 0.4 0.0 0.0 0.0 3.9 0.1 0.0 0.0 0.0 3.4 3.2 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 0.0 26.0 0.1 0.0 0.0 0.1 0.0 11.4 2.9 0.0 0.0 20.2 0.1 0.5 6.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 2.0 1.8 1.9 1.3 0.7 0.7 0.4 29.8 42.2 0.0 12.3 0.6 1.4 0.6 2.5 72.3 29.6 0.0 0.0 1.9 0.0 7.2 3.0 0.6 15.4 0.0 2.3 2.2 0.3 21.6 9.2 0.0 0.2 0.0 32.8 0.0 0.0 1.1 0.0 0.7 1.7 0.0 62.9 1.3 3.1 17.3 0.0 1.9 5.6 0.0 0.5 0.7 0.6 1.0 20.1 0.0 69.5 9.5 ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting alpha subunit" P20648 19 35550043-35563658 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "stomach 1: 120.1" "Group enriched" "Detected in some" 4 "Early spermatids: 7.3;Late spermatids: 15.2" "Cancer enriched" "Detected in single" 21 "stomach cancer: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "THP-1: 1.2;U-138 MG: 1.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA039154, HPA076684" Enhanced NA NA 790000 "HPA039154: AB_10672772, HPA076684: " "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.77e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-3)" "unprognostic (3.90e-3)" "unprognostic (3.92e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" 0.1 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.6 0.1 0.1 3.4 0.1 0.0 0.1 0.1 4.9 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 2.1 0.1 0.1 120.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 1.5 0.3 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.6 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.6 0.0 0.0 0.0 0.0 0.0 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56646068 "Enzymes, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cytotrophoblasts: 693.2;Distal tubular cells: 1049.5;Proximal tubular cells: 698.1;Syncytiotrophoblasts: 952.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 100000000 Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 41.3 66.2 32.4 34.1 53.4 39.3 33.1 55.4 92.6 26.1 73.0 34.4 36.1 68.1 27.9 28.5 58.6 28.5 36.9 225.0 33.2 34.9 95.2 85.7 28.3 39.2 40.5 35.5 25.1 42.7 85.2 30.1 31.3 69.6 29.0 78.5 42.8 64.7 38.1 236.2 42.3 74.6 35.5 24.9 33.5 51.0 31.4 18.3 47.5 38.4 123.6 45.8 36.6 32.8 41.2 91.7 40.2 90.1 36.3 46.6 105.6 66.5 81.0 64.4 99.3 58.1 62.1 113.8 67.7 63.2 117.1 66.8 131.5 74.3 118.4 73.4 83.4 49.0 89.2 135.6 82.1 106.1 55.5 93.9 129.9 75.6 80.6 72.0 145.2 92.0 76.1 82.9 91.5 118.2 89.2 96.2 88.4 116.9 136.5 98.2 61.7 107.5 85.4 108.4 88.2 156.0 103.7 72.1 150.9 127.5 118.6 73.7 65.5 103.5 148.2 115.1 70.7 139.1 109.8 65.2 46.1 51.4 67.3 73.1 65.9 81.9 122.5 69.4 97.2 70.6 40.2 64.6 34.6 40.2 80.6 44.9 41.2 38.0 42.7 91.7 31.7 31.1 36.7 17.8 36.3 90.1 46.3 46.6 105.6 32.4 53.4 55.4 92.6 33.2 34.9 40.5 35.5 69.6 18.3 125.0 160.8 0.0 0.0 0.0 0.0 0.0 0.0 188.7 149.0 263.5 0.0 693.2 1049.5 441.8 0.0 0.0 0.0 0.0 323.3 482.8 0.0 0.0 133.7 0.0 535.7 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 490.5 0.0 0.0 298.7 0.0 0.0 698.1 0.0 0.0 0.0 0.0 0.0 0.0 952.2 0.0 0.0 0.0 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747019-113812056 "Disease related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Translocase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 467.9;Late spermatids: 569.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.6" "Group enriched" "Detected in all" 6 "dendritic cells: 16.4;granulocytes: 33.6;monocytes: 15.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 2700000 "Vesicles, Cytosol" Nucleoplasm "CAB006910: , HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favorable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 12.8 19.8 24.1 10.4 33.2 7.4 12.7 34.8 52.8 14.0 11.1 10.3 5.6 9.3 7.5 8.2 13.2 10.0 10.8 4.7 26.2 38.2 47.9 18.2 12.3 11.4 25.4 25.0 6.2 10.5 39.3 13.5 12.3 52.0 11.2 11.8 14.7 18.0 8.4 4.5 12.6 7.9 8.2 13.6 13.7 10.9 8.9 8.3 9.6 21.0 5.7 13.6 10.2 8.2 3.8 16.4 33.6 15.4 3.8 3.4 6.0 25.4 11.6 14.6 12.7 30.9 13.8 15.6 13.8 21.1 14.5 20.1 21.8 20.5 20.9 32.9 20.1 16.1 16.6 33.0 18.2 19.1 9.5 9.1 18.5 18.0 16.8 25.5 13.6 21.7 18.6 12.6 18.8 13.2 22.6 23.6 10.6 21.1 15.8 21.5 16.7 9.9 6.1 18.3 17.8 14.6 8.6 10.6 23.7 39.8 24.3 28.3 10.4 24.2 16.5 18.1 21.0 25.0 11.0 21.7 13.6 10.1 9.3 8.2 16.6 17.8 19.3 26.6 17.2 15.0 9.2 15.4 5.2 2.8 11.7 2.6 3.8 2.6 2.7 16.4 2.9 2.5 2.9 33.6 3.8 9.5 4.6 3.4 6.0 24.1 33.2 34.8 52.8 26.2 38.2 25.4 25.0 52.0 8.3 26.8 28.3 28.9 13.2 27.0 92.7 7.9 33.1 14.7 19.4 94.2 39.3 18.1 69.6 25.2 467.9 26.0 24.0 0.0 23.9 18.8 17.8 28.2 10.4 64.4 67.8 95.3 53.6 36.2 95.4 569.6 16.7 67.0 43.9 49.5 25.8 42.1 22.3 24.6 21.5 62.8 37.3 6.5 14.6 25.3 14.3 41.9 36.7 17.1 21.3 21.1 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Sertoli cells: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 9.8 7.4 2.6 8.6 4.6 6.4 8.5 2.3 2.9 8.2 7.7 5.9 9.6 4.8 9.5 7.6 10.0 5.7 4.5 5.1 2.9 2.8 9.0 3.3 9.3 9.3 4.1 1.7 7.3 6.3 13.2 15.9 5.0 4.3 8.2 4.4 5.2 12.3 10.3 6.1 15.9 8.5 7.8 6.3 10.8 7.0 2.7 6.0 15.6 6.0 7.1 11.7 11.8 7.0 2.3 1.4 10.7 2.4 1.7 3.0 1.2 2.6 6.8 4.5 4.6 4.3 4.6 0.8 4.0 5.5 2.3 4.8 0.9 3.0 3.8 5.9 3.9 2.9 3.2 5.9 3.2 4.4 5.6 4.0 1.9 6.6 0.7 5.5 3.3 3.6 4.8 1.3 5.0 1.5 5.5 6.2 3.9 15.5 14.7 4.3 2.2 3.6 1.1 1.3 9.1 1.5 3.0 7.6 12.8 3.9 7.3 1.4 17.4 9.8 2.4 5.0 3.0 1.8 1.1 7.8 3.1 3.2 4.4 1.5 4.8 8.4 4.4 5.2 2.0 4.8 8.3 2.0 5.5 2.4 1.9 1.2 2.0 1.7 1.7 1.3 2.3 2.1 3.0 10.7 1.7 2.4 1.4 0.6 1.2 2.6 4.6 2.3 2.9 2.9 2.8 4.1 1.7 4.3 6.0 0.0 5.9 2.0 4.6 6.5 6.1 4.5 0.0 9.4 3.4 8.7 3.9 1.8 1.7 4.3 0.4 7.1 2.8 0.0 12.0 1.9 5.4 5.7 9.2 2.4 12.0 1.6 4.6 9.2 9.9 1.1 6.6 5.4 18.6 1.8 6.2 3.8 6.0 2.9 9.2 5.4 3.6 32.3 4.2 0.9 5.4 14.4 1.8 5.0 4.1 5.5 ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 18.5;liver: 13.5" "Cell type enhanced" "Detected in many" 13 "Cone photoreceptor cells: 21.6;Early spermatids: 29.4;Late spermatids: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 19.3;CACO-2: 11.1;HEL: 29.3;Hep G2: 10.1;RPTEC TERT1: 17.1" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Golgi apparatus" "HPA009137: AB_2668214, HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" 3.4 0.7 1.8 2.4 2.9 1.8 1.6 7.0 2.8 1.4 6.8 1.1 1.1 10.5 1.6 1.9 1.1 1.9 18.5 1.8 2.1 2.1 2.1 13.5 1.2 1.1 1.6 1.1 2.0 1.7 7.7 1.2 7.1 3.5 1.9 2.6 1.4 3.0 1.1 1.1 0.7 9.6 1.5 1.1 1.6 4.5 7.1 1.6 1.1 1.1 1.1 1.1 2.1 1.1 0.0 0.0 1.0 0.3 0.0 0.5 0.1 0.4 1.6 3.0 2.7 0.6 0.5 19.3 0.8 0.2 0.9 0.7 11.1 0.1 0.0 0.3 1.4 2.1 0.2 2.1 2.4 0.6 0.2 4.1 29.3 0.3 10.1 0.9 0.3 6.9 1.2 2.9 0.1 1.1 1.3 2.1 2.1 7.8 0.0 0.9 0.5 0.1 0.7 1.0 3.7 1.0 1.1 0.8 0.0 17.1 1.9 2.2 1.3 1.1 1.6 1.1 3.4 4.6 0.2 1.1 0.1 1.0 1.6 0.3 0.3 0.4 0.1 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 1.8 2.9 7.0 2.8 2.1 2.1 1.6 1.1 3.5 1.6 6.0 0.0 1.7 0.7 0.3 3.0 1.8 0.0 5.3 3.4 1.8 21.6 10.2 0.0 1.5 29.4 1.1 6.1 0.0 0.8 4.4 0.6 1.3 0.0 16.3 2.0 0.0 2.4 3.7 1.0 57.4 2.0 0.0 1.7 0.0 4.0 0.5 1.7 2.9 0.7 1.3 6.7 6.5 0.9 1.1 1.9 0.4 3.8 0.0 4.7 1.1 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 38.9" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 2: 61.4;Cone photoreceptor cells: 76.6;Horizontal cells: 58.8;Intestinal endocrine cells: 81.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 17.2;Daudi: 28.1;HEL: 9.9;REH: 9.7;SH-SY5Y: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA 20000 Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 5.3 8.6 14.2 8.0 29.6 18.5 4.8 7.2 32.0 3.1 11.3 27.3 8.4 4.2 3.4 11.6 2.9 3.5 2.8 8.0 13.7 8.8 4.0 2.1 10.6 12.5 18.0 17.4 15.1 10.0 38.9 6.9 2.6 15.3 7.9 10.7 3.9 4.4 15.2 16.9 3.2 8.1 3.1 23.1 7.8 10.5 2.8 24.9 8.9 34.9 1.9 10.3 4.5 4.0 4.4 3.8 0.9 3.3 3.2 7.3 0.9 0.0 0.1 0.3 17.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.2 28.1 8.0 0.1 0.0 1.4 4.0 0.0 0.0 4.4 2.8 9.9 1.0 0.4 0.0 2.4 0.2 0.3 0.0 0.0 0.0 0.3 0.1 6.3 0.0 3.2 0.0 1.2 3.5 0.8 1.3 1.1 0.3 9.7 0.0 3.1 6.1 0.3 3.1 9.3 0.2 5.9 0.0 0.7 1.9 0.0 0.2 0.0 1.3 0.3 0.0 1.1 0.0 5.7 0.4 3.4 0.1 0.0 1.0 0.9 6.0 0.4 3.2 2.6 1.9 6.5 0.9 4.4 2.9 7.3 0.9 3.2 3.3 3.8 1.4 0.9 14.2 29.6 7.2 22.1 13.7 8.8 18.0 17.4 15.3 24.9 26.8 61.4 5.1 1.7 1.3 17.7 12.8 0.0 0.0 9.1 5.2 76.6 0.0 3.3 0.0 3.0 9.3 46.1 0.0 2.2 0.1 2.2 16.2 8.1 1.1 1.5 58.8 81.2 17.8 7.5 2.3 3.1 3.8 3.3 1.8 23.3 1.0 0.8 7.0 1.8 1.4 41.3 0.0 0.3 1.1 4.1 1.3 0.0 21.8 23.1 2.4 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25372071-26025851 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 34.9;pituitary gland: 37.0;testis: 10.4" "Cell type enhanced" "Detected in many" 13 "Cone photoreceptor cells: 90.3;Early spermatids: 29.4;Rod photoreceptor cells: 86.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3;naive CD8 T-cell: 3.3" "Lineage enriched" "Detected in single" 12 "T-cells: 3.3" "Group enriched" "Detected in some" 4 "HMC-1: 21.6;JURKAT: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 1.1 4.9 11.2 1.4 11.4 0.8 2.2 34.9 30.2 1.1 1.3 1.3 0.0 1.4 2.1 4.8 0.9 0.9 1.0 1.0 9.4 11.8 1.3 0.8 2.3 1.9 6.7 10.4 1.2 1.9 0.9 37.0 1.2 19.8 1.1 1.3 3.1 1.0 1.0 1.3 0.9 1.5 1.0 3.5 1.3 1.8 10.4 1.4 0.0 1.0 0.0 1.2 1.2 0.3 0.0 0.0 0.2 0.0 0.2 3.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.0 0.6 1.4 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 21.6 0.2 0.0 0.0 0.0 0.6 0.5 9.6 0.0 0.0 1.7 0.3 3.7 0.0 2.0 0.0 0.7 0.0 2.7 1.0 0.2 0.1 3.3 0.0 0.1 0.3 0.1 0.4 0.0 0.4 0.2 0.1 1.1 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.8 0.6 0.0 0.0 2.3 3.3 0.2 0.2 0.0 0.0 0.7 0.6 11.2 11.4 34.9 18.4 9.4 11.8 6.7 10.4 19.8 1.4 0.0 9.8 0.9 0.1 0.9 20.0 2.2 2.5 0.0 0.0 0.0 90.3 1.2 0.0 0.3 29.4 1.5 0.0 0.0 0.0 0.3 0.4 0.2 4.7 0.0 2.4 20.6 0.0 0.0 0.0 24.5 0.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 1.1 0.6 86.2 12.9 0.0 12.9 9.9 0.4 0.9 0.5 0.0 0.0 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803101 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease mutation, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 198.4;Mucus-secreting cells: 179.9;Undifferentiated cells: 138.5" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 27.5;HBF TERT88: 24.7;RT4: 58.5" "Low region specificity" "Detected in many" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 3.8 2.3 0.0 1.8 0.0 0.0 3.4 0.0 0.3 4.5 21.3 8.9 2.4 0.8 6.7 2.6 4.8 1.8 0.2 0.0 2.1 3.0 3.6 0.0 0.1 0.7 10.7 2.7 1.1 1.3 6.0 19.3 5.8 2.8 0.4 3.6 11.1 2.0 0.2 1.2 13.3 0.0 5.7 0.2 12.8 5.4 6.0 2.0 4.7 2.1 0.7 1.3 0.3 10.2 3.5 0.1 0.1 3.6 6.6 5.0 19.9 19.4 21.0 13.1 2.6 8.9 0.7 6.0 27.5 8.3 15.2 0.1 4.2 24.7 0.2 0.4 0.1 0.9 0.9 1.1 0.2 0.1 1.0 3.8 6.3 11.1 15.5 11.0 0.2 0.1 0.4 12.1 4.9 0.2 0.2 0.2 11.0 1.0 0.1 0.1 0.2 2.9 58.5 0.4 0.3 0.4 12.3 0.1 0.5 3.8 0.6 12.6 17.1 0.6 2.7 4.6 0.2 0.1 0.2 0.4 0.2 0.9 0.8 2.1 0.5 1.3 0.9 1.0 2.7 1.0 0.7 0.5 6.0 0.9 1.0 4.7 0.7 1.2 2.0 0.4 0.3 17.9 18.2 4.5 44.8 6.9 0.7 4.0 33.1 40.2 48.9 38.4 0.0 17.1 0.0 20.8 2.0 26.8 198.4 0.0 45.9 1.9 5.1 74.4 4.6 16.8 2.3 6.4 65.7 30.1 3.8 0.0 0.3 1.3 6.8 1.0 179.9 0.2 33.7 74.8 0.0 0.1 1.1 12.9 17.6 0.3 1.2 14.3 9.2 1.5 138.5 100.6 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325553-154351307 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Ito cells: 12.3;Peritubular cells: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.1;T-cells: 6.5" "Cell line enhanced" "Detected in many" "ASC diff: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046680 Approved NA NA "HPA046680: AB_2679749" "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 13.6 7.0 5.5 15.0 7.1 3.4 11.9 26.8 8.9 29.1 11.2 7.4 11.5 8.6 28.9 15.2 14.4 21.5 18.4 11.7 7.0 6.8 6.6 2.6 12.2 16.1 6.2 5.8 27.5 5.3 5.1 13.9 10.9 6.1 15.3 6.8 12.5 5.4 16.4 4.3 6.1 11.8 29.4 5.1 14.7 11.4 12.7 5.1 18.9 11.2 8.1 13.6 20.5 24.9 0.6 0.7 3.1 0.0 0.9 6.5 1.0 0.7 5.1 6.5 6.7 41.8 28.3 0.1 15.7 26.2 9.1 10.9 0.1 0.2 0.6 8.3 37.9 6.0 3.2 7.8 1.8 6.4 17.2 6.3 6.5 6.3 5.9 12.7 0.0 5.1 18.2 0.4 13.8 13.2 12.0 14.0 8.3 12.9 15.8 7.7 6.7 12.2 0.8 15.5 0.1 6.5 13.6 4.5 23.4 1.7 0.1 5.8 8.0 4.1 0.9 9.8 9.7 4.8 4.9 12.2 13.8 7.0 17.3 4.7 21.9 26.8 3.9 4.8 0.7 8.4 3.1 0.0 3.0 2.2 0.0 1.5 0.6 3.5 3.7 0.0 0.4 2.9 2.5 0.1 0.9 0.0 0.7 6.5 1.0 5.5 7.1 26.8 8.9 7.0 6.8 6.2 5.8 6.1 5.1 3.0 5.0 2.2 1.5 2.3 0.7 5.1 0.0 6.7 3.4 0.0 2.0 0.1 0.0 1.2 0.4 8.4 0.0 0.0 0.2 0.4 8.1 4.3 7.0 0.9 0.4 7.9 0.0 12.3 1.0 0.4 10.6 0.0 6.8 0.0 0.0 2.6 1.4 0.0 13.8 0.1 0.4 0.0 6.2 2.6 3.6 1.4 0.2 8.2 0.0 0.4 ATP8B3 ATPIK ENSG00000130270 "ATPase phospholipid transporting 8B3" O60423 19 1782075-1812276 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 55.8" "Cell type enhanced" "Detected in many" 17 "Late spermatids: 8.9;Spermatocytes: 26.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 10.6;Karpas-707: 18.7;U-266/70: 15.6" "Not detected" "Not detected" NA NA "unprognostic (6.50e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.05e-5)" "unprognostic (6.66e-2)" "unprognostic (7.91e-2)" "unprognostic (1.86e-2)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (2.55e-3)" "unprognostic (1.28e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (4.80e-9)" "unprognostic (8.05e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-2)" "unprognostic (1.19e-1)" 0.6 3.1 0.2 3.1 0.2 7.1 0.6 0.2 0.7 1.5 0.7 0.2 0.2 0.4 1.8 4.3 0.6 0.6 1.0 2.2 0.3 0.2 0.4 1.0 1.9 1.1 0.2 0.5 1.9 0.3 0.3 0.6 0.5 0.4 0.5 0.4 1.1 0.5 1.6 0.2 0.8 0.7 1.0 0.7 4.8 0.4 55.8 0.0 5.5 0.7 1.2 1.5 0.8 1.0 0.1 1.2 1.7 6.9 2.2 2.8 1.2 0.6 5.1 0.6 0.8 0.7 0.5 0.0 2.0 3.1 2.0 1.9 0.0 2.1 2.2 2.3 1.6 0.2 0.1 0.4 0.0 0.9 2.1 0.1 0.7 2.5 1.0 0.2 1.3 10.6 0.2 0.2 0.0 2.2 3.0 0.5 6.5 1.6 18.7 3.3 0.0 1.4 3.9 0.1 0.3 2.4 2.2 0.4 0.3 2.7 0.1 0.0 0.7 0.5 0.0 0.3 0.6 0.6 6.5 4.9 0.1 4.1 0.8 2.1 15.6 7.6 0.6 4.0 6.5 2.6 0.0 2.2 1.7 1.9 6.9 0.8 0.0 1.4 1.1 1.2 0.1 0.6 1.9 0.6 2.2 1.8 0.5 2.8 1.2 0.2 0.2 0.2 0.7 0.3 0.2 0.2 0.5 0.4 0.0 0.0 1.1 0.0 0.6 0.7 1.9 1.4 2.5 0.0 0.0 0.0 2.0 0.1 0.0 0.8 6.2 1.0 0.0 0.0 0.2 0.9 1.4 0.3 1.1 0.8 1.3 0.0 0.0 5.5 3.3 8.9 0.3 0.5 1.7 0.0 0.0 0.8 0.2 0.0 0.4 0.0 0.6 0.0 0.9 26.5 3.2 1.3 0.3 2.5 0.0 0.1 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;cervix, uterine: 26.0;endometrium 1: 18.2" "Group enriched" "Detected in many" 4 "Early spermatids: 23.4;granulocytes: 19.6;Hofbauer cells: 12.9;Kupffer cells: 29.9;Late spermatids: 19.9;Macrophages: 17.3;T-cells: 8.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 6.9;NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 19.1;NB-4: 7.3;THP-1: 12.3;U-937: 38.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 2.3 1.2 1.6 1.5 2.1 28.1 1.0 0.6 0.9 26.0 1.5 1.7 1.6 0.4 18.2 3.5 0.6 9.5 3.1 0.8 2.5 0.9 1.0 1.2 3.2 0.7 2.7 0.1 3.9 0.4 0.2 1.1 2.9 2.1 0.7 1.2 0.8 0.9 0.6 0.4 0.5 1.1 2.7 3.1 2.3 0.6 0.9 4.6 0.8 0.5 0.8 2.1 1.3 1.5 0.0 2.2 6.9 1.7 10.6 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 5.2 0.0 3.0 0.6 0.0 0.0 5.3 19.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.4 38.5 0.0 6.9 1.7 2.4 0.5 0.8 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 10.6 0.3 0.0 0.0 0.8 1.6 2.1 0.6 0.9 2.5 0.9 2.7 0.1 2.1 4.6 0.0 3.4 1.3 0.1 1.3 0.2 1.2 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 23.4 0.5 0.4 0.0 0.0 1.6 3.3 0.5 19.6 2.8 12.9 0.0 0.0 1.8 29.9 19.9 1.7 17.3 1.7 1.0 0.3 0.5 0.0 0.0 0.7 0.8 0.0 0.0 4.3 0.4 0.6 0.3 2.4 8.6 0.0 0.1 ATP9A "ATPIIA, KIAA0611" ENSG00000054793 "ATPase phospholipid transporting 9A (putative)" O75110 20 51596514-51768634 "Enzymes, Predicted membrane proteins, Transporters" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.7" "Cell type enhanced" "Detected in many" 5 "Intestinal endocrine cells: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 6.3;NK-cell: 2.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.3;NK-cells: 2.2" "Cell line enhanced" "Detected in many" "EFO-21: 29.3;SK-BR-3: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020699, HPA035630" Enhanced NA NA "CAB020699: , HPA035630: AB_10669526" "unprognostic (5.19e-2)" "unprognostic (5.28e-2)" "unprognostic (3.46e-1)" "unprognostic (1.05e-1)" "unprognostic (3.76e-1)" "unprognostic (1.37e-1)" "unprognostic (3.76e-2)" "unprognostic (4.79e-2)" "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "prognostic favorable (5.67e-5)" "unprognostic (5.82e-2)" "unprognostic (5.81e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" 18.5 8.2 23.7 3.9 31.8 2.0 11.2 29.8 64.7 5.6 12.2 19.9 8.2 9.1 8.6 13.1 8.8 16.9 8.2 7.7 24.3 26.8 6.8 5.4 6.7 2.6 21.1 23.9 13.2 10.0 22.7 8.3 3.6 22.5 14.3 11.3 4.1 14.9 11.3 9.2 4.1 11.5 8.7 18.9 2.2 14.0 12.4 15.8 0.8 18.7 2.9 2.4 7.4 5.6 0.0 0.0 6.3 0.2 2.2 0.8 1.8 9.7 8.3 6.9 15.4 20.3 15.1 0.1 3.5 6.7 2.3 0.7 19.1 20.3 0.0 29.3 14.5 11.7 7.8 9.0 5.1 2.3 7.5 2.7 0.0 9.2 7.7 2.8 0.0 0.0 5.0 10.4 0.5 1.4 5.4 12.5 1.8 0.0 0.0 2.6 13.6 0.7 0.0 1.2 9.9 10.6 1.5 0.0 0.0 4.7 13.7 13.0 9.3 14.0 28.1 5.1 2.5 5.3 0.2 8.1 19.3 5.2 7.5 1.5 0.0 0.1 0.3 5.1 0.0 1.7 6.3 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.4 2.2 0.1 0.0 0.0 1.8 23.7 31.8 29.8 34.9 24.3 26.8 21.1 23.9 22.5 15.8 14.9 12.8 0.0 10.2 2.6 32.1 11.5 30.6 17.4 14.8 17.4 3.9 0.3 1.7 18.0 0.6 5.4 32.5 0.0 14.8 0.2 7.1 27.0 1.1 10.0 4.5 41.3 53.0 11.1 2.7 1.7 12.4 1.6 3.3 0.0 36.1 4.5 21.7 24.6 21.9 1.2 6.4 6.5 7.1 0.9 1.5 3.6 0.2 0.5 19.7 25.5 ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 119.1;Alveolar cells type 2: 156.1;Ciliated cells: 168.6;Club cells: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved NA NA "HPA029364: AB_10602595" "unprognostic (2.84e-3)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (7.32e-2)" "unprognostic (7.66e-4)" "unprognostic (2.45e-2)" "unprognostic (7.43e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.92e-3)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-2)" 14.5 11.0 11.7 16.8 11.6 30.1 11.7 16.8 15.2 14.3 10.7 17.5 15.2 7.1 21.8 17.6 11.3 11.9 14.5 10.7 11.4 8.2 13.1 16.7 13.9 13.2 10.8 9.7 18.2 14.3 25.8 15.5 10.9 11.3 12.8 11.4 12.3 14.2 17.3 18.8 13.3 9.1 14.8 17.1 9.7 11.5 22.1 12.4 19.3 14.6 9.6 16.4 14.6 13.3 9.8 8.4 14.2 16.3 8.6 12.2 6.9 15.2 8.0 11.2 12.4 5.8 9.8 8.7 8.2 5.6 4.9 4.2 8.6 10.9 8.5 13.7 5.9 4.7 6.9 9.2 4.6 8.0 13.1 3.9 10.0 9.2 6.1 7.7 18.2 10.7 7.8 5.8 8.0 4.9 7.3 6.8 10.5 9.6 21.5 6.9 13.3 11.9 7.1 15.9 9.7 10.0 11.4 9.3 11.4 7.0 13.2 8.3 8.7 9.2 9.7 5.6 20.2 11.4 10.8 12.0 10.4 16.9 4.7 5.4 10.8 17.6 19.1 6.0 12.1 10.7 14.2 12.0 9.1 8.4 10.1 9.8 9.0 9.6 8.1 8.4 9.8 12.2 9.5 13.0 8.6 16.3 8.0 7.4 6.9 11.7 11.6 16.8 15.2 11.4 8.2 10.8 9.7 11.3 12.4 119.1 156.1 11.9 6.2 5.0 34.8 10.3 15.3 168.6 95.5 8.7 39.3 5.6 1.7 5.4 19.8 9.8 5.4 0.0 4.9 3.3 7.8 5.5 40.6 6.4 12.9 39.7 11.5 9.2 11.3 34.5 14.7 12.2 6.8 5.4 7.8 17.8 6.6 9.0 10.6 3.1 39.0 6.5 7.3 26.1 16.4 6.4 6.4 16.0 8.1 7.0 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX, chromatin remodeler" P46100 X 77504878-77786269 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" NA NA "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321" "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 16.4 16.6 24.5 18.9 29.3 24.3 16.3 48.2 26.4 20.6 15.4 7.1 18.9 10.2 20.2 17.1 13.5 13.8 13.4 15.1 22.9 15.8 16.6 12.2 15.9 18.6 21.1 21.3 25.4 18.3 35.7 28.1 15.9 20.2 18.4 12.6 7.1 15.8 16.5 20.1 14.1 13.5 22.3 15.3 20.1 15.6 6.5 22.4 23.7 19.8 12.7 16.5 19.9 21.1 21.9 12.8 21.5 11.5 14.6 17.7 5.7 15.3 24.7 25.4 17.1 12.7 17.1 9.0 13.3 12.3 9.9 11.7 8.4 13.5 21.4 13.7 14.1 18.6 13.7 20.4 7.9 16.8 12.0 13.3 12.9 29.4 6.2 6.9 16.7 4.4 11.2 7.8 14.5 13.9 12.3 17.4 13.5 15.1 24.6 12.3 12.1 12.9 8.7 18.4 7.1 19.2 21.0 35.2 10.9 9.6 20.6 14.5 25.1 26.8 10.5 8.8 17.2 8.5 8.6 24.0 14.0 21.6 15.6 9.3 7.3 22.7 19.2 10.2 13.3 12.3 21.3 6.9 13.8 17.7 8.7 17.1 19.2 16.3 13.7 5.1 21.9 16.8 13.5 21.5 14.6 11.5 12.8 12.8 5.7 24.5 29.3 48.2 26.4 22.9 15.8 21.1 21.3 20.2 22.4 148.9 213.6 88.0 96.7 82.1 217.2 263.3 58.6 120.5 117.2 68.0 200.3 58.0 19.9 72.8 3.1 123.5 43.3 23.3 72.0 39.7 90.3 99.7 106.6 45.6 60.7 149.4 121.7 91.4 84.5 4.9 150.4 86.3 59.1 120.0 68.3 114.7 80.3 40.3 195.6 28.6 231.4 90.5 113.3 13.6 49.5 73.8 50.0 94.4 62.6 104.6 ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106625 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: AB_2686124" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" 17.8 10.3 10.2 9.1 11.6 14.3 12.8 18.7 12.1 16.0 11.8 12.2 11.9 6.4 17.9 12.4 17.7 9.5 11.2 10.4 9.0 9.9 9.9 16.0 12.3 11.6 16.3 9.5 14.0 10.3 11.9 17.2 11.7 13.8 15.8 11.7 8.6 11.4 10.2 6.1 21.0 8.7 20.6 16.5 12.6 9.0 14.8 14.3 16.2 11.5 12.0 15.6 15.4 13.6 9.8 14.5 11.4 18.8 7.0 8.5 5.3 5.6 11.1 10.1 9.3 14.7 14.4 19.7 6.4 10.5 8.2 11.5 8.1 15.7 11.5 12.8 10.5 9.7 9.9 7.7 14.1 18.2 13.1 2.3 4.9 5.4 11.8 12.1 8.6 8.8 11.6 12.6 14.3 15.0 11.0 12.6 12.9 6.5 8.6 12.4 22.0 9.0 7.8 7.1 18.8 9.2 7.2 18.5 6.5 10.5 12.8 3.4 6.0 15.6 6.6 8.8 14.1 12.3 6.1 6.7 8.1 11.9 5.2 3.4 7.5 12.5 10.6 6.0 8.5 4.7 11.4 13.4 9.4 5.9 14.5 7.0 7.1 6.9 6.5 14.5 9.8 7.6 8.5 11.3 7.0 18.8 8.4 6.8 5.3 10.2 11.6 18.7 12.1 9.0 9.9 16.3 9.5 13.8 14.3 14.9 14.3 18.1 26.1 22.6 32.4 17.3 17.8 12.0 12.5 40.1 47.1 17.4 13.3 17.7 18.3 43.4 11.7 0.0 15.0 23.8 25.4 29.1 23.2 19.1 20.8 25.4 15.4 39.3 27.2 18.5 62.7 31.8 21.9 30.7 16.0 20.6 17.6 17.5 61.2 14.6 45.6 45.3 35.8 30.5 60.9 26.5 21.2 23.0 19.4 25.1 ATXN3L MJDL ENSG00000123594 "Ataxin 3 like" Q9H3M9 X 13318236-13320399 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 8.0" "Group enriched" "Detected in some" 58 "Early spermatids: 59.4;Late spermatids: 131.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.0" "HPA024123, HPA027539" Uncertain NA NA "HPA024123: AB_1845133, HPA027539: AB_10602435" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 131.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 0.0 0.0 0.0 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101360417-101383519 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 128.4" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 745.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.1;CACO-2: 3.4;Hep G2: 2.4;OE19: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles NA NA 470000 Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.8 0.0 0.1 0.1 0.2 128.4 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.0 0.7 0.1 0.1 6.1 0.4 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.3 3.4 0.1 0.6 0.2 0.0 0.3 0.3 0.1 0.2 0.5 0.3 0.1 0.5 0.2 2.4 0.0 0.9 0.3 0.0 1.0 0.1 0.0 0.1 0.0 0.8 0.7 0.4 0.5 0.1 0.2 0.3 1.0 2.6 0.7 0.2 1.1 0.2 0.6 0.2 0.3 0.4 0.4 0.2 0.5 0.2 0.0 0.2 0.1 0.6 0.6 0.2 0.4 0.4 0.6 0.5 0.5 0.2 0.6 0.3 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.8 0.4 89.2 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 745.7 0.0 0.0 0.0 11.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "brain: 53.0;pancreas: 161.1" "Cell type enhanced" "Detected in many" 12 "Cone photoreceptor cells: 111.9;Early spermatids: 89.1;Late spermatids: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" 6.5 7.1 12.1 3.8 18.8 2.2 5.5 9.6 22.4 9.8 4.6 42.5 2.7 3.4 9.3 5.6 7.6 8.6 9.1 5.9 16.9 12.4 6.8 12.1 7.3 2.8 28.8 15.0 11.4 161.1 12.8 4.2 6.3 26.4 6.5 4.7 6.9 5.3 9.9 6.2 7.2 3.6 11.7 53.0 5.7 4.9 4.1 21.4 0.0 6.3 2.3 2.8 6.7 5.5 4.0 2.2 0.7 3.2 2.2 6.7 1.1 3.9 4.7 9.7 14.8 32.2 34.7 0.4 21.3 18.6 10.4 8.5 3.6 6.3 0.8 5.2 38.6 7.8 6.9 10.3 6.1 8.5 2.3 5.5 2.4 7.9 4.3 15.9 0.8 0.5 30.0 9.6 13.2 12.9 25.7 8.9 1.4 0.8 0.4 19.0 14.3 0.6 1.9 6.3 4.1 10.4 1.8 4.4 0.8 4.4 2.2 12.6 14.1 7.9 1.0 2.3 8.9 10.2 2.7 12.2 18.7 2.0 19.5 6.8 0.3 0.3 0.4 8.8 1.2 13.0 0.6 2.0 0.7 2.0 3.2 5.2 4.0 6.7 5.3 2.2 1.8 3.1 2.7 0.0 2.2 1.3 1.3 6.3 1.1 12.1 18.8 9.6 21.7 16.9 12.4 28.8 15.0 26.4 21.4 17.9 8.5 0.0 3.8 4.1 53.4 8.1 17.8 4.0 20.5 5.2 111.9 0.8 5.0 4.7 89.1 5.2 1.5 0.0 17.3 0.9 11.5 2.8 2.3 31.6 7.9 54.0 20.8 6.7 12.6 222.6 17.8 5.8 3.3 1.8 2.4 16.6 5.8 4.0 20.8 5.4 48.1 6.5 6.6 3.2 1.7 3.0 0.7 1.0 2.7 2.5 BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-site APP-cleaving enzyme 2" Q9Y5Z0 21 41167801-41282518 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 9 "Glandular cells: 265.1;Syncytiotrophoblasts: 430.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 4.8;eosinophil: 8.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "OE19: 42.8;SK-BR-3: 24.4;SK-MEL-30: 18.9;WM-115: 17.3" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" NA NA "HPA035416: AB_2732467" "unprognostic (1.71e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" 16.1 2.5 1.4 5.9 1.6 0.9 13.8 0.9 2.0 9.0 11.0 3.4 5.6 5.1 10.3 10.7 13.0 6.8 38.9 7.2 1.7 1.6 11.4 4.4 4.9 21.6 2.7 0.5 8.4 29.0 3.3 2.2 17.2 4.4 22.7 7.4 8.7 28.3 4.4 10.6 5.5 5.4 7.8 5.9 7.0 31.6 5.1 1.4 1.3 9.9 7.6 14.3 11.8 33.6 1.0 0.0 8.4 0.0 0.3 0.0 0.0 14.4 1.3 4.8 0.0 1.3 1.3 0.0 3.6 0.0 2.5 2.1 0.0 5.6 0.0 6.8 4.5 3.9 4.5 0.0 8.5 0.8 0.0 7.2 2.8 1.6 0.0 0.6 0.0 6.8 3.5 1.6 0.3 1.8 11.1 7.2 3.3 0.0 0.0 3.4 2.7 1.6 0.0 3.8 42.8 7.4 0.5 0.0 5.4 4.4 0.9 0.2 0.0 0.2 24.4 18.9 0.6 6.8 0.0 7.1 4.0 2.9 3.3 5.1 0.0 0.0 0.0 8.3 0.0 17.3 4.8 0.0 8.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 1.6 0.9 2.0 1.7 1.6 2.7 0.5 4.4 1.4 11.9 15.7 28.2 70.7 16.5 0.3 6.1 124.9 96.4 81.9 19.2 2.0 98.7 79.6 150.6 17.8 58.1 13.6 0.0 91.4 48.8 34.0 265.1 88.9 0.5 22.6 0.0 17.7 36.8 13.4 7.9 13.3 4.8 170.4 4.6 61.8 2.5 75.6 17.3 17.7 1.1 0.2 0.0 30.1 0.5 0.4 10.3 430.4 2.2 37.1 109.5 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401013-52410350 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850" "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favorable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 13.8 17.6 35.6 14.7 33.3 37.3 13.5 21.8 50.4 12.5 17.0 16.3 11.5 12.4 14.7 14.6 21.2 12.1 15.7 16.4 41.5 15.5 16.6 19.0 14.9 15.2 19.4 27.6 16.9 16.3 30.0 11.1 14.8 19.6 14.4 14.9 15.6 17.9 14.6 24.8 40.5 13.9 14.5 10.0 16.1 13.3 37.3 14.7 18.6 15.3 12.9 16.0 14.1 11.7 5.5 8.4 11.3 5.0 3.0 8.5 3.9 14.8 16.9 20.6 17.4 19.9 12.8 23.2 14.7 19.1 24.0 18.6 20.5 13.9 21.4 7.4 20.5 27.1 12.1 21.6 23.8 15.3 21.1 20.5 26.4 35.8 21.2 18.5 24.8 23.5 19.1 31.9 26.5 14.2 13.2 19.1 41.2 22.6 18.9 18.0 12.9 29.4 34.0 23.2 11.8 20.6 12.7 16.7 21.1 14.8 24.1 7.8 25.3 18.1 5.3 21.5 12.1 14.8 34.3 20.4 21.7 20.0 26.0 27.3 28.7 37.7 30.6 23.7 26.2 25.6 3.4 5.0 7.4 8.5 3.9 4.0 5.0 6.8 6.9 3.3 5.5 4.9 6.4 11.3 3.0 3.1 8.4 6.0 3.9 35.6 33.3 21.8 50.4 41.5 15.5 19.4 27.6 19.6 14.7 0.0 13.6 15.0 8.8 28.0 15.3 19.3 10.2 5.3 9.1 24.4 0.0 12.2 10.0 12.0 81.1 12.4 17.6 0.0 14.3 13.1 11.8 9.7 20.7 25.8 11.0 9.5 10.4 15.4 19.3 32.6 9.5 10.2 11.8 11.8 12.9 9.9 12.6 15.3 11.0 14.6 11.3 19.4 13.2 30.9 12.4 20.6 10.1 11.3 16.4 8.5 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837472 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 145.4" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 360.7" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Karpas-707: 131.7" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" NA NA 13000000000 "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 14.0 3.9 6.7 6.2 4.3 0.4 1.9 3.6 9.1 24.4 15.5 4.7 8.3 1.8 20.2 13.4 20.0 18.0 2.2 7.8 6.1 4.4 2.8 145.4 3.7 0.7 5.5 2.7 10.3 1.1 0.4 1.2 0.5 4.7 4.7 5.3 0.7 1.0 10.5 1.1 2.8 6.4 13.9 3.4 3.7 1.9 1.8 6.1 1.0 0.8 0.4 0.5 9.7 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 14.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.9 0.0 1.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 4.2 0.2 0.0 1.4 4.4 0.6 5.2 0.0 131.7 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 4.8 10.9 0.1 0.0 0.0 0.1 0.0 0.0 7.5 0.0 5.8 0.0 0.0 3.2 0.0 0.0 1.3 0.5 0.0 0.2 1.3 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 4.3 3.6 4.3 6.1 4.4 5.5 2.7 4.7 6.1 0.0 0.0 0.0 0.3 4.8 0.9 4.3 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 1.5 0.0 0.0 0.0 0.0 2.2 0.2 0.0 360.7 0.1 1.6 0.0 6.2 5.3 5.5 2.0 0.0 18.6 0.0 0.0 34.4 0.0 0.0 0.0 2.9 1.0 0.0 4.6 0.3 0.1 3.0 0.0 0.0 0.0 0.1 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "Bloom syndrome RecQ like helicase" P54132 15 90717327-90816165 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.7" "Cell type enhanced" "Detected in many" 6 "B-cells: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 1.8 0.4 3.1 11.4 1.5 5.5 0.6 4.7 2.6 0.7 1.9 0.9 0.5 1.4 1.2 1.1 2.9 0.4 1.3 1.0 2.3 2.4 0.9 0.5 2.0 7.7 2.8 0.2 0.9 0.4 0.0 1.2 3.6 0.5 0.7 2.5 0.7 7.8 0.0 1.7 0.6 2.8 0.5 1.9 6.7 1.4 4.9 0.5 36.7 0.6 3.1 9.3 1.4 0.7 7.4 1.2 4.3 1.6 4.6 5.0 1.6 5.5 7.8 8.8 5.1 0.0 0.4 5.5 4.1 1.2 4.7 5.1 6.9 3.9 14.2 2.6 1.1 5.9 9.2 13.5 3.7 6.1 8.6 10.0 14.9 8.5 2.2 0.0 14.3 7.4 0.0 0.0 4.7 2.4 0.6 3.3 7.7 12.8 4.4 4.9 3.4 10.7 7.8 9.3 12.1 1.7 10.9 16.5 5.5 1.1 9.9 6.5 6.1 3.3 4.5 2.6 8.6 3.1 11.7 1.8 3.4 6.3 3.5 8.8 3.3 13.2 14.8 1.9 10.1 5.9 2.5 1.0 4.3 3.1 1.2 4.8 7.4 2.8 3.8 1.2 4.3 2.0 2.2 0.8 4.6 1.6 1.2 5.0 1.6 3.1 1.5 4.7 1.7 2.3 2.4 2.8 0.2 0.5 0.5 3.0 12.8 18.6 0.5 0.2 2.9 8.4 0.0 9.4 6.8 0.0 2.0 1.8 1.7 0.9 2.0 0.7 0.0 0.0 0.6 6.5 1.5 0.6 12.7 0.5 4.8 0.0 0.0 2.5 9.7 1.6 0.0 3.8 0.0 1.0 1.2 1.2 0.8 0.0 0.4 0.0 6.5 0.0 0.4 12.0 11.8 0.5 0.8 8.7 2.3 0.3 BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248195-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 67.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 59000000 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: AB_10805479, HPA064307: AB_2685241" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (2.54e-2)" "unprognostic (3.91e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (6.69e-3)" "unprognostic (1.95e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" 11.2 8.3 9.0 17.1 10.2 8.5 14.2 12.1 14.5 10.5 9.8 8.5 9.6 6.7 13.1 12.2 15.7 8.4 10.1 9.7 7.5 7.2 13.6 7.5 13.6 20.3 9.5 8.5 8.8 15.3 15.0 8.3 14.6 9.2 8.4 8.5 7.3 12.8 9.5 15.0 67.5 10.0 15.7 11.1 13.2 9.2 12.4 8.6 24.7 9.3 15.5 13.6 10.8 11.7 4.6 6.6 0.9 5.7 9.8 17.3 6.3 10.2 16.2 15.6 10.8 10.7 11.5 7.6 9.5 5.9 15.1 13.0 23.7 3.0 30.4 17.0 7.7 6.8 7.1 33.8 13.0 12.8 8.0 26.6 18.6 14.5 20.1 15.7 33.9 11.5 13.6 0.9 11.8 6.8 12.4 22.1 25.5 39.7 12.4 6.2 7.7 42.0 24.8 15.0 0.0 7.6 36.4 40.6 20.1 12.0 9.1 36.1 12.9 8.4 16.5 10.4 28.2 11.2 17.5 14.0 9.3 18.8 4.1 16.8 15.0 30.9 41.1 7.1 0.0 12.4 0.0 5.7 0.9 10.5 3.9 17.3 4.6 12.6 13.7 6.5 4.2 11.6 12.3 0.7 9.8 1.9 6.6 12.4 6.3 9.0 10.2 12.1 14.5 7.5 7.2 9.5 8.5 9.2 8.6 3.0 13.0 12.3 14.0 14.2 18.2 16.5 12.7 6.7 2.3 10.4 11.8 41.1 6.6 14.9 8.2 17.9 8.9 0.0 12.2 31.7 13.3 8.5 43.8 6.6 22.1 12.7 17.2 28.3 21.8 5.2 15.0 10.4 10.1 10.0 7.6 10.9 8.9 8.6 23.3 17.0 16.0 6.5 15.3 9.7 16.7 11.0 23.0 18.7 10.7 5.9 BMP1 PCOLC ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22164736-22212326 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "lung: 72.2;placenta: 106.2" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 2: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 2100000 "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 6.9 11.7 2.7 3.6 4.6 1.1 5.9 7.8 4.2 8.1 5.8 3.1 3.7 4.4 9.4 5.2 4.8 7.7 5.4 3.4 2.6 1.3 4.9 9.2 72.2 3.2 3.4 1.5 5.2 3.7 2.8 2.2 106.2 3.5 6.5 4.7 4.6 2.4 4.6 2.4 6.8 5.7 11.0 3.6 3.2 2.9 2.2 3.6 1.0 7.1 2.4 2.9 9.9 9.5 0.0 0.9 0.1 1.4 0.8 2.2 0.4 4.6 4.8 1.3 6.2 15.2 11.3 6.8 20.2 16.8 10.3 9.6 2.5 3.0 1.1 12.7 18.5 6.4 10.1 1.5 5.3 2.0 1.0 2.1 1.7 7.3 2.8 12.4 0.7 3.4 12.8 8.5 8.0 2.6 18.3 10.0 0.6 2.1 2.0 5.6 1.7 0.4 1.0 0.8 6.9 2.6 1.1 3.3 4.9 8.9 0.7 0.8 3.3 14.6 0.8 3.3 5.6 0.9 2.0 12.6 2.7 5.9 6.5 5.9 1.0 0.6 0.2 5.3 2.7 7.4 0.0 1.4 0.0 2.2 0.7 1.4 0.0 0.4 1.0 0.0 0.0 0.3 1.7 0.1 0.8 0.5 0.9 0.0 0.4 2.7 4.6 7.8 4.2 2.6 1.3 3.4 1.5 3.5 3.6 6.0 61.3 0.5 5.3 5.6 1.5 3.0 2.5 1.4 2.3 5.2 0.0 2.4 0.0 21.2 0.5 10.5 18.6 0.0 7.1 8.6 24.4 2.5 15.0 15.8 4.1 1.6 2.9 14.1 4.0 0.5 9.5 3.5 10.1 0.0 5.5 3.2 11.4 11.0 10.3 3.1 1.0 25.8 18.4 0.9 3.6 4.5 20.4 1.9 9.7 6.4 BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Enterocytes: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" NA NA 170000 "Nuclear speckles" "HPA048461: AB_2680404" "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favorable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" 11.1 24.1 12.7 22.2 17.2 2.9 13.4 13.7 16.5 12.9 27.9 15.9 14.4 30.5 10.6 8.0 14.9 11.5 16.1 11.6 11.3 10.8 31.0 17.0 11.5 21.5 14.0 10.6 13.5 8.6 14.1 20.2 12.7 11.9 9.6 22.5 11.8 22.2 12.2 7.6 10.6 49.0 12.3 17.6 12.0 12.9 10.4 13.3 15.6 13.8 12.6 28.8 13.5 10.4 18.9 10.9 11.6 8.5 12.1 13.8 7.6 11.8 9.8 7.4 5.9 13.2 10.6 11.0 16.0 7.8 13.8 12.8 12.9 24.1 60.2 21.1 10.4 6.4 8.6 14.9 13.4 11.2 21.6 17.3 10.8 12.7 15.9 7.7 28.8 10.2 9.9 6.4 20.4 7.6 8.6 10.8 17.4 18.8 6.0 13.1 6.7 16.5 7.9 6.3 9.6 12.1 11.9 21.3 17.0 17.1 16.3 13.7 11.3 20.2 24.3 13.2 7.5 19.1 10.0 18.0 8.6 6.7 11.9 19.8 10.6 25.5 28.5 7.7 10.8 19.4 11.6 7.8 5.0 11.0 8.5 8.7 18.9 11.3 11.0 9.0 14.1 13.8 10.2 1.1 12.1 7.8 10.9 11.5 7.6 12.7 17.2 13.7 16.5 11.3 10.8 14.0 10.6 11.9 13.3 26.8 19.2 20.8 9.9 3.0 12.5 11.1 15.3 10.7 17.0 14.0 9.8 11.9 11.6 15.3 1.9 4.2 50.6 0.0 13.9 11.4 7.2 5.8 3.5 11.3 8.6 6.4 18.5 4.9 5.7 2.4 8.9 8.3 10.1 7.2 12.6 10.1 15.8 24.6 12.7 21.7 11.2 12.9 6.6 12.5 12.6 4.4 21.1 7.0 15.5 10.7 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61681266-61863521 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Group enriched" "Detected in many" 11 "Early spermatids: 136.2;Late spermatids: 148.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;granulocytes: 2.1;T-cells: 3.7" "Cell line enhanced" "Detected in many" "MCF7: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 1.0 0.9 0.7 6.3 3.5 9.1 1.1 0.6 1.4 1.4 2.6 0.2 0.6 2.8 1.5 1.2 3.7 0.8 1.8 0.4 0.5 0.5 0.6 2.3 1.3 4.0 0.5 0.9 2.1 1.3 0.1 0.4 1.7 0.7 1.0 2.8 0.4 1.4 0.0 0.4 2.7 5.5 1.0 0.5 2.3 1.3 10.8 0.4 30.1 0.4 2.0 6.6 1.3 1.7 2.2 0.5 2.1 0.3 0.6 3.7 0.5 12.5 4.3 12.4 7.1 0.4 1.1 2.7 11.6 6.8 12.4 16.1 4.4 4.0 7.5 2.7 2.4 3.6 4.5 6.4 2.4 16.8 1.9 7.8 7.6 6.8 5.4 0.1 9.8 4.5 0.2 0.1 9.9 2.6 1.7 2.7 7.4 5.3 5.1 7.8 42.2 15.5 3.4 2.7 3.0 3.7 9.7 23.9 3.6 1.7 5.7 5.0 12.9 4.5 1.6 1.8 4.9 4.2 3.8 2.3 18.3 13.4 6.7 13.3 3.2 6.1 8.0 3.7 4.7 4.5 2.1 0.3 1.5 0.5 0.2 0.6 2.2 1.2 0.6 0.4 1.8 1.8 0.9 1.0 0.6 0.2 0.5 3.7 0.5 0.7 3.5 0.6 1.4 0.5 0.5 0.5 0.9 0.7 0.4 0.0 0.3 1.5 1.3 2.1 0.1 0.5 0.0 1.4 6.8 0.0 0.0 0.7 0.0 0.3 136.2 0.3 0.9 0.0 0.2 2.5 0.6 0.1 0.0 3.0 1.4 0.0 0.0 0.6 0.3 148.4 1.1 0.4 3.3 1.0 1.5 0.3 0.5 0.0 1.1 0.0 0.2 0.0 0.9 13.3 4.5 0.4 0.2 0.8 2.5 0.3 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15702950-15738313 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 59.5;bone marrow: 54.9;intestine: 61.3" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 39.0;Kupffer cells: 36.4;Macrophages: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 52.7;neutrophil: 59.5" "Group enriched" "Detected in many" 105 "dendritic cells: 16.6;granulocytes: 59.5;monocytes: 52.7" "Cell line enhanced" "Detected in many" "THP-1: 37.1;TIME: 20.4;U-937: 24.2;WM-115: 22.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 170000000 "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 14.3 2.0 1.1 5.6 2.0 54.9 6.6 0.8 1.5 7.2 33.8 1.5 2.1 20.4 6.4 7.0 4.6 5.6 10.3 14.5 1.8 0.8 6.6 3.7 9.4 9.6 1.3 1.9 5.5 1.0 0.4 1.3 8.0 1.3 7.5 4.0 5.4 2.8 2.2 3.4 3.5 61.3 7.9 1.5 13.6 2.4 2.4 1.2 2.8 3.5 2.9 1.8 7.5 16.1 0.4 16.6 59.5 52.7 0.1 0.3 19.6 0.2 5.5 0.5 0.4 13.5 3.2 0.7 10.5 1.0 9.6 10.8 0.1 5.7 0.3 0.9 5.3 0.2 0.1 1.5 0.2 8.2 0.3 0.2 2.5 0.3 0.2 3.4 3.3 7.3 2.7 0.7 6.1 0.5 0.4 1.5 2.3 0.3 0.2 5.6 0.1 1.0 1.9 1.2 0.4 1.1 0.3 0.7 0.2 0.3 0.3 0.7 2.1 0.2 0.3 7.0 0.5 0.2 37.1 20.4 0.3 0.5 3.7 0.4 0.2 0.0 0.3 1.3 24.2 22.1 7.6 52.7 3.9 0.2 19.8 0.3 0.4 0.1 0.1 16.6 0.2 0.2 0.1 59.5 0.1 13.6 5.5 0.2 19.6 1.1 2.0 0.8 1.5 1.8 0.8 1.3 1.9 1.3 1.2 3.0 3.0 0.0 0.8 4.0 0.2 0.8 5.1 2.7 1.2 1.8 0.0 14.0 1.7 4.1 2.7 2.1 3.2 0.0 2.3 18.7 18.6 0.5 16.1 1.8 39.0 0.0 1.2 3.7 36.4 0.7 2.8 29.9 13.5 0.0 7.0 0.3 0.8 7.0 2.1 6.7 0.0 6.5 10.8 2.3 1.2 2.6 5.9 0.0 16.6 2.7 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15647640 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" NA NA 2900000000 "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 18.5 17.9 7.5 3.9 10.2 4.4 13.5 17.0 11.8 11.2 28.1 19.6 12.2 25.3 12.3 34.1 7.1 10.3 10.4 6.9 8.0 6.8 20.0 50.7 8.2 5.2 12.3 9.5 17.2 26.6 19.6 11.1 10.7 9.3 10.7 9.4 20.0 11.6 12.1 6.9 6.5 40.5 7.9 8.8 7.6 12.9 15.0 12.6 5.9 14.8 3.8 6.2 11.7 9.1 8.4 13.7 31.0 11.9 7.5 15.6 8.7 3.8 10.8 3.3 3.2 28.3 7.8 19.6 7.0 9.4 8.3 15.0 3.8 10.3 1.0 8.4 16.2 3.4 4.3 2.6 8.3 9.7 3.3 5.5 5.9 14.5 11.6 6.8 2.9 6.9 9.5 8.6 21.9 2.2 19.6 15.9 2.4 3.8 13.8 23.3 4.6 1.6 3.4 3.6 8.2 6.0 2.1 8.3 13.0 8.0 7.8 2.3 5.7 8.3 2.0 11.0 7.7 10.2 5.6 10.8 9.0 6.9 8.4 4.4 3.2 4.9 1.2 10.5 3.5 6.5 31.0 11.9 25.2 13.2 11.1 12.3 8.4 14.1 11.3 12.1 7.8 12.2 9.2 10.8 7.5 8.4 13.7 15.6 8.7 7.5 10.2 17.0 11.8 8.0 6.8 12.3 9.5 9.3 12.6 6.0 8.3 10.4 10.9 5.3 12.4 5.3 45.9 17.4 3.4 17.4 17.7 22.1 5.0 15.4 24.9 7.1 10.6 23.3 24.6 16.7 10.3 6.2 4.7 58.9 13.6 4.8 6.9 23.4 8.9 12.5 30.0 8.2 10.1 10.8 7.5 18.0 12.6 17.3 17.0 23.2 43.4 12.9 5.2 20.4 6.8 4.8 19.3 13.8 7.6 9.1 C1R ENSG00000159403 "Complement C1r" P00736 12 7080209-7092607 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 370.2" "Group enriched" "Detected in many" 5 "Fibroblasts: 462.9;Hepatocytes: 1385.8;Leydig cells: 1057.9;Peritubular cells: 364.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 2.0;gdT-cell: 1.6;MAIT T-cell: 2.0;memory CD4 T-cell: 1.4;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.8;naive CD8 T-cell: 2.9;neutrophil: 2.5;NK-cell: 3.2;T-reg: 1.4" "Group enriched" "Detected in many" 6 "granulocytes: 2.5;NK-cells: 3.2;T-cells: 3.4" "Cell line enhanced" "Detected in many" "ASC diff: 181.7;ASC TERT1: 92.7;BJ hTERT+: 80.0;BJ hTERT+ SV40 Large T+ RasG12V: 49.3;HSkMC: 107.4" "Low region specificity" "Detected in all" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol "Secreted to blood" NA NA 14000000000 "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 45.8 17.4 2.6 18.1 3.8 0.0 82.0 1.4 2.8 36.7 24.5 2.4 11.2 5.0 27.2 66.8 38.1 33.3 46.7 49.5 1.9 1.8 27.5 370.2 25.3 46.8 3.5 2.0 103.5 11.4 1.4 6.3 10.3 4.6 47.8 15.3 17.7 12.8 13.2 16.0 10.7 14.4 53.2 6.2 35.1 19.8 39.3 1.9 2.3 30.6 20.7 15.1 46.8 83.8 0.4 0.0 2.5 0.4 3.2 3.4 0.8 0.1 1.5 0.1 1.3 181.7 92.7 0.1 20.4 80.0 24.2 49.3 0.2 0.3 0.0 0.6 15.9 1.6 0.3 1.7 0.8 3.4 1.9 0.1 0.0 0.6 0.6 34.9 0.1 0.2 107.4 0.5 11.0 0.8 18.4 0.4 0.1 0.0 2.5 3.1 0.0 0.9 0.1 0.8 0.0 0.1 1.1 0.5 0.1 0.1 0.9 0.0 0.3 14.7 0.4 0.4 0.2 0.0 0.0 0.0 5.8 0.9 26.7 0.1 0.1 0.4 0.0 8.3 0.1 0.8 0.0 0.4 2.0 1.6 0.1 2.0 0.0 1.4 3.4 0.0 0.4 2.8 2.9 2.5 3.2 0.0 0.0 1.4 0.8 2.6 3.8 1.4 2.8 1.9 1.8 3.5 2.0 4.6 1.9 20.8 84.7 28.4 53.6 48.5 0.2 14.6 168.2 6.7 34.2 17.4 2.0 2.9 3.3 164.2 3.5 51.3 0.3 23.3 39.1 4.8 462.9 14.1 9.3 1385.8 10.3 0.0 0.0 128.9 25.4 9.4 1057.9 10.1 50.6 2.8 0.6 15.1 74.1 0.6 364.9 5.0 0.9 168.1 97.8 5.7 4.1 35.0 4.3 13.1 0.7 9.8 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 351.6" "Cell type enhanced" "Detected in many" 21 "Hepatocytes: 2464.3;Leydig cells: 1104.9;Peritubular cells: 601.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "neutrophil: 6.2" "Lineage enriched" "Detected in single" 17 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "ASC diff: 99.3;ASC TERT1: 132.1;BJ hTERT+: 42.1;HSkMC: 70.1" "Low region specificity" "Detected in all" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 13000000000 Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 48.7 16.6 3.3 18.7 4.1 0.0 55.7 1.9 3.1 35.3 31.1 2.9 12.7 6.8 32.2 50.0 38.3 46.4 47.2 34.4 2.5 1.1 18.0 351.6 31.4 21.1 6.3 3.2 98.8 15.5 1.9 6.0 8.5 6.5 52.1 18.6 26.1 14.6 12.4 18.2 14.7 19.2 47.6 8.8 32.5 24.6 37.2 2.3 3.2 30.5 22.7 18.8 48.6 73.0 0.2 0.1 6.2 0.3 0.2 0.1 0.0 0.0 2.2 0.1 1.3 99.3 132.1 0.4 17.9 42.1 9.5 17.4 0.0 0.2 0.0 2.4 22.2 2.5 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.6 4.7 29.9 0.2 0.1 70.1 0.3 7.7 0.5 11.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 10.9 0.2 0.2 2.1 0.0 0.0 0.0 4.4 0.3 16.9 0.0 0.0 0.0 0.1 9.5 0.1 0.2 0.6 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 6.2 0.2 0.1 0.1 0.0 0.0 3.3 4.1 1.9 3.1 2.5 1.1 6.3 3.2 6.5 2.3 14.9 34.2 18.3 17.5 67.8 0.6 21.4 152.8 6.7 20.5 3.5 0.0 2.9 1.7 170.0 5.7 37.8 0.0 46.7 37.9 3.5 388.0 7.4 4.7 2464.3 7.1 4.8 0.0 105.6 49.3 8.8 1104.9 9.4 84.4 1.8 0.0 15.1 43.6 0.0 601.8 4.1 0.9 135.8 123.7 5.0 4.1 47.0 2.2 4.3 0.0 3.0 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 132.7" "Cell type enhanced" "Detected in many" 17 "Alveolar cells type 2: 116.0;Hepatocytes: 339.0;Hofbauer cells: 221.2" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "classical monocyte: 2.9;intermediate monocyte: 6.4;non-classical monocyte: 6.5" "Lineage enriched" "Detected in single" 8 "monocytes: 6.5" "Group enriched" "Detected in some" 5 "Hep G2: 17.3;Karpas-707: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" CAB016775 Supported "Secreted to blood" NA NA 52000000000 "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 9.2 3.2 0.9 4.8 1.5 0.8 5.0 1.2 1.3 2.0 5.3 1.8 1.6 2.5 2.0 4.8 1.9 3.3 3.2 5.4 0.8 0.8 13.1 132.7 19.4 13.1 1.2 0.3 2.7 2.1 0.8 2.8 7.6 1.7 1.8 4.3 2.9 2.4 1.5 0.7 1.6 6.6 3.5 1.8 12.1 1.9 2.0 1.0 1.8 1.2 0.8 3.4 2.7 1.5 0.2 0.5 0.8 6.5 0.1 0.3 1.2 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 17.3 0.3 0.0 0.2 0.9 0.1 0.2 0.0 0.2 0.0 0.3 0.1 54.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 1.4 0.6 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 2.4 0.1 0.1 0.2 0.2 0.0 0.2 6.7 1.0 0.2 0.3 0.0 0.1 2.9 0.0 0.1 6.4 0.1 0.1 0.1 0.1 0.5 0.2 0.3 0.2 0.8 0.1 6.5 0.0 0.1 1.2 0.9 1.5 1.2 1.2 0.8 0.8 1.2 0.3 1.7 1.0 23.8 116.0 3.0 1.0 3.0 1.4 0.4 10.2 9.4 6.8 1.8 0.0 1.6 0.0 0.4 0.1 0.7 2.8 23.3 2.4 1.8 15.8 5.9 3.5 339.0 221.2 1.6 2.4 25.2 60.2 0.8 6.4 8.4 3.3 10.0 4.1 0.0 7.1 15.3 1.1 30.0 0.8 0.0 2.3 0.6 0.9 2.5 3.3 3.2 3.9 2.5 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217390-27243943 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA057266, HPA069341" Supported Supported Nucleoplasm No No 26000 Nucleoplasm "CAB007781: AB_562057, HPA057266: AB_2683387, HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 12.0 11.9 10.1 23.1 12.4 11.1 18.9 13.3 13.1 14.6 12.4 10.9 9.7 12.1 21.0 18.0 16.3 16.6 15.8 9.8 8.6 8.8 13.1 22.9 13.0 27.9 11.8 9.5 24.4 18.1 10.7 16.4 10.6 10.1 12.5 11.6 12.9 11.7 18.3 12.3 26.0 13.2 17.3 12.5 18.7 11.4 21.3 10.8 35.2 13.8 14.1 18.5 12.7 13.1 5.1 4.9 0.8 2.3 3.7 7.9 2.6 25.3 23.0 10.2 20.5 16.7 13.7 8.1 10.8 7.5 13.6 9.7 26.0 10.1 22.7 9.8 9.8 10.5 14.4 30.1 14.3 10.3 14.8 24.3 32.4 17.5 13.5 8.3 25.5 16.4 10.4 11.8 19.8 22.6 6.3 14.6 21.1 22.8 12.7 12.0 25.5 16.2 38.0 24.6 10.7 17.5 28.5 30.7 23.6 10.1 13.0 20.6 10.3 15.0 10.7 12.6 7.9 8.4 10.7 13.1 20.7 17.1 16.1 21.6 26.4 16.9 46.4 8.3 24.6 17.8 0.0 1.2 0.5 4.7 2.3 4.0 5.1 6.5 7.7 2.7 5.0 4.3 4.3 0.8 3.7 1.2 4.9 7.9 2.6 10.1 12.4 13.3 13.1 8.6 8.8 11.8 9.5 10.1 10.8 3.0 3.8 2.2 3.7 3.3 8.9 4.8 15.3 2.7 5.7 1.8 15.7 4.7 0.0 6.1 1.1 3.8 2.5 0.0 3.0 4.7 5.0 2.4 4.6 4.9 6.9 6.4 6.3 4.3 2.4 1.4 5.8 2.2 3.3 5.4 5.2 4.1 5.3 0.0 9.2 1.3 6.2 0.0 5.1 4.9 10.0 3.0 1.8 4.5 6.8 2.0 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991717-79009867 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Mucus-secreting cells: 134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 92.2;T-47d: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA NA 2300000 "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 13.8 15.3 9.6 13.1 10.2 8.1 13.0 12.2 10.8 17.7 43.8 12.3 25.4 25.5 12.0 14.3 27.5 10.0 19.5 10.8 9.0 6.9 10.3 17.7 11.1 11.5 12.5 7.7 10.4 14.7 13.1 11.8 33.0 12.0 36.7 41.5 7.9 30.3 41.4 9.0 8.9 27.2 8.0 12.4 18.1 25.8 19.0 10.3 14.1 12.4 8.9 14.4 10.3 13.7 4.1 3.8 17.5 4.4 3.1 6.2 4.4 22.2 24.4 6.8 9.9 6.5 7.8 8.8 13.8 12.1 14.8 12.6 11.6 21.1 5.4 8.1 9.6 18.1 11.3 5.8 10.8 14.9 9.0 10.6 7.0 7.4 9.6 5.6 6.7 11.1 8.0 7.0 13.7 7.5 8.8 25.6 9.1 8.8 9.2 9.8 12.1 10.1 4.0 4.7 92.2 26.0 5.7 11.2 6.1 6.5 11.2 9.9 9.9 7.3 48.8 10.4 11.4 60.2 8.0 12.7 22.2 20.1 9.9 17.2 10.9 9.0 5.3 14.2 5.2 13.9 6.1 3.8 8.1 6.2 4.4 6.1 4.1 4.6 5.2 3.8 2.9 4.5 4.4 17.5 3.1 2.9 2.7 3.8 4.4 9.6 10.2 12.2 10.8 9.0 6.9 12.5 7.7 12.0 10.3 26.8 19.4 13.7 13.8 14.7 5.9 11.6 15.3 6.7 10.3 12.2 13.7 30.3 3.3 30.3 11.4 14.3 61.6 23.3 25.4 31.5 12.3 34.8 5.7 12.1 21.5 4.8 49.0 54.6 9.2 10.4 10.9 11.3 13.5 11.8 134.8 6.7 27.4 49.1 7.1 6.1 8.5 6.5 7.2 23.2 5.5 11.4 84.9 10.2 83.2 16.5 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 90.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 28000000 Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 22.0 15.6 9.6 23.8 11.6 18.2 18.8 17.7 20.1 25.8 33.3 8.4 23.0 25.4 19.3 30.2 86.9 28.1 39.1 21.4 8.8 11.2 27.8 21.3 19.4 19.5 10.8 9.7 21.4 24.9 13.3 14.1 38.1 16.8 27.3 17.0 15.8 39.7 24.3 24.2 38.9 49.9 16.5 7.7 21.3 20.7 8.3 6.7 32.1 37.5 50.2 53.7 33.7 35.2 16.7 22.8 34.5 24.8 15.7 19.6 28.5 48.4 25.8 7.4 16.4 13.4 17.1 22.5 14.4 22.9 17.0 13.0 16.4 43.6 12.1 24.1 27.3 19.8 71.6 9.6 60.8 5.5 12.9 7.6 28.9 14.9 16.0 13.4 6.8 40.6 18.8 32.7 14.4 7.0 16.0 29.0 8.8 17.2 9.8 13.8 31.1 13.3 21.5 21.3 24.8 23.4 13.2 7.6 7.3 23.0 90.0 13.3 9.8 15.2 58.9 13.9 8.3 25.3 13.4 25.2 13.2 9.0 28.2 6.5 6.0 4.4 14.4 23.1 8.3 14.3 34.3 24.8 34.5 19.6 23.7 15.7 15.6 15.5 17.7 22.8 16.7 9.1 12.5 15.8 15.7 14.0 17.9 16.6 28.5 9.6 11.6 17.7 20.1 8.8 11.2 10.8 9.7 16.8 6.7 23.8 24.7 31.9 110.9 53.1 6.6 17.9 68.8 30.8 33.0 73.3 19.6 201.3 33.2 164.8 0.5 23.3 141.6 0.0 101.4 88.1 42.3 51.8 46.1 31.0 78.5 20.6 42.6 26.4 45.7 0.4 40.3 38.8 45.5 146.9 72.1 33.2 133.6 105.2 47.7 26.9 15.0 38.8 36.4 0.5 2.0 60.2 164.4 49.8 101.5 141.7 CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Alveolar cells type 1: 366.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol NA NA 1500000 Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (6.21e-4)" 56.2 41.0 23.8 20.7 22.2 11.1 61.1 26.1 20.9 40.3 44.8 18.3 23.3 14.5 29.1 44.5 56.3 40.1 58.9 33.0 26.5 13.1 41.6 13.3 58.6 18.2 27.4 18.2 32.4 26.8 53.7 12.7 26.4 23.8 27.2 44.4 16.5 62.5 31.9 48.1 16.5 22.7 35.7 32.3 15.9 48.2 17.2 24.7 5.0 29.9 39.7 35.9 28.3 38.8 9.0 41.6 1.7 29.1 6.0 28.7 28.2 46.1 29.6 9.5 6.3 31.7 44.0 9.1 43.7 63.5 31.8 18.1 23.4 37.2 0.0 14.4 48.5 25.0 28.9 10.2 69.1 29.6 11.8 10.6 0.8 15.1 2.9 28.5 2.4 1.5 23.5 22.4 49.5 26.5 57.1 63.0 0.0 13.3 12.4 93.6 0.9 0.1 2.1 5.2 5.7 38.7 3.9 31.0 0.7 54.8 2.7 2.0 11.0 22.5 61.5 13.6 24.0 9.3 11.1 96.9 29.8 24.7 25.6 56.0 3.7 6.9 0.1 74.6 5.2 32.7 1.7 29.1 1.7 28.7 19.5 24.5 9.0 20.0 27.7 41.6 3.6 6.4 17.4 1.5 6.0 17.5 1.9 19.9 28.2 23.8 22.2 26.1 20.9 26.5 13.1 27.4 18.2 23.8 24.7 366.3 110.0 19.7 85.8 42.0 12.0 35.9 96.8 180.7 191.1 50.6 31.4 18.1 154.2 234.2 86.1 110.2 114.4 0.0 171.9 77.1 101.6 155.1 26.6 6.0 36.6 12.7 23.6 33.2 58.4 173.5 71.7 66.7 106.3 13.6 104.2 15.8 261.3 139.7 64.7 17.0 17.0 38.8 112.7 3.0 3.2 24.1 6.9 57.7 90.7 256.2 CAPN3 "CANP3, LGMD2, LGMD2A, nCL-1, p94" ENSG00000092529 "Calpain 3" P20807 15 42359500-42412318 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6;skeletal muscle: 210.9" "Cell type enhanced" "Detected in many" 20 "Early spermatids: 403.1;Late spermatids: 111.1;Melanocytes: 457.2" "Cancer enriched" "Detected in some" 10 "melanoma: 9.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 23 "SK-MEL-30: 77.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040052 Enhanced NA NA "HPA040052: AB_2676821" "unprognostic (1.06e-2)" "unprognostic (1.31e-1)" "unprognostic (4.00e-2)" "unprognostic (8.71e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-2)" "unprognostic (2.11e-4)" "unprognostic (3.12e-3)" "unprognostic (2.82e-1)" "unprognostic (2.47e-1)" "unprognostic (2.37e-3)" "unprognostic (3.26e-2)" "unprognostic (3.91e-4)" "unprognostic (5.56e-3)" "unprognostic (2.43e-1)" "unprognostic (8.93e-3)" "unprognostic (1.38e-1)" 5.7 1.8 13.0 2.3 32.1 16.7 3.8 3.1 22.9 2.1 2.4 65.6 0.0 2.2 3.1 47.0 4.2 2.5 3.0 3.6 19.9 11.5 22.1 6.3 6.7 3.4 50.7 19.5 3.1 1.4 3.4 1.7 2.0 39.0 3.0 3.2 5.0 3.1 3.1 210.9 19.7 2.3 2.8 52.6 3.3 2.1 4.1 47.3 0.0 1.6 27.6 3.0 2.7 2.3 1.5 1.7 0.9 2.6 1.3 3.2 1.4 0.1 0.2 0.2 0.3 3.3 3.2 0.3 1.2 0.7 0.1 0.2 0.3 0.2 0.0 0.4 0.6 0.1 1.8 0.1 1.3 0.1 0.3 0.3 0.2 0.5 1.0 0.1 0.5 0.6 2.1 2.0 0.2 0.5 0.7 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.5 0.1 0.0 0.2 0.5 0.0 0.7 0.8 0.5 0.0 0.0 0.0 0.1 77.0 0.3 0.0 1.8 0.3 0.0 0.1 1.6 0.2 0.4 0.7 0.0 0.2 0.9 0.7 0.0 2.6 0.0 2.8 0.6 2.8 0.4 0.3 1.0 1.7 1.5 0.2 3.2 0.9 1.3 0.2 1.6 1.3 1.4 13.0 32.1 3.1 22.9 19.9 11.5 50.7 19.5 39.0 47.3 11.9 34.6 0.0 0.8 17.9 1.5 0.3 0.0 0.0 5.7 1.8 2.0 0.5 1.7 0.0 403.1 0.7 1.6 0.0 0.0 0.4 0.8 0.6 1.1 6.6 24.8 0.0 0.0 2.5 4.5 111.1 4.9 4.6 457.2 1.0 1.8 3.6 0.0 4.5 3.2 36.6 3.7 0.0 0.8 9.4 4.9 7.4 2.7 1.9 1.9 0.7 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665734 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 32.0;stomach 1: 85.8" "Cell type enhanced" "Detected in many" 12 "Alveolar cells type 2: 123.4;Club cells: 94.4;Mucus-secreting cells: 49.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 13 "OE19: 51.0;RT4: 30.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.2 0.0 0.5 10.3 0.3 0.0 7.5 0.2 0.3 1.0 7.9 0.6 0.2 2.2 0.3 3.3 0.6 0.4 32.0 0.2 0.2 0.1 2.5 0.2 13.0 0.2 0.2 0.2 0.2 8.0 0.0 0.2 0.8 0.2 4.6 9.9 0.2 4.6 0.3 0.3 1.5 4.0 3.2 0.2 0.2 85.8 0.4 0.2 0.3 0.2 1.5 1.2 15.1 3.9 0.4 0.0 1.1 0.0 0.0 1.4 1.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.1 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 51.0 1.6 0.0 0.0 0.0 0.6 30.2 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.9 0.7 0.0 0.0 0.1 1.4 1.1 0.0 0.0 0.0 0.0 1.5 0.5 0.3 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.2 26.8 123.4 0.0 6.0 0.1 0.0 2.2 15.3 24.1 94.4 24.4 0.0 0.1 0.0 0.4 1.4 0.0 30.0 0.0 19.7 0.0 0.0 3.3 10.4 0.0 0.5 0.0 2.9 0.0 0.0 3.5 1.7 0.4 0.0 0.0 49.6 0.0 21.9 16.9 3.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.0 13.2 15.4 CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025443-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 64.2;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" 7 "Hofbauer cells: 83.5;Kupffer cells: 119.3;Macrophages: 125.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 38.4;HBEC3-KT: 18.2;HHSteC: 20.6;U-937: 45.4" "Region enhanced" "Detected in many" "olfactory region: 22.8" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "CAB002685: , HPA003056: AB_1846037" "unprognostic (1.21e-3)" "unprognostic (3.02e-1)" "unprognostic (9.47e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (6.67e-2)" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.03e-2)" "unprognostic (2.30e-2)" "unprognostic (3.18e-1)" "unprognostic (5.19e-2)" 7.4 3.9 6.6 15.1 17.0 8.2 6.9 3.5 7.0 4.1 12.8 2.2 2.9 34.0 3.0 4.2 10.6 4.3 7.3 4.9 9.3 3.0 6.4 5.8 20.5 16.2 16.7 2.6 4.4 3.4 0.2 3.7 8.7 13.3 6.1 13.9 3.7 7.0 3.2 1.6 9.9 37.2 5.2 17.4 40.7 5.6 1.5 11.0 4.1 3.7 5.6 9.0 9.7 13.2 7.3 39.6 40.5 64.2 11.1 34.3 31.2 0.4 0.1 0.0 1.8 2.0 4.3 0.3 1.9 38.4 4.8 13.5 0.0 0.2 6.2 0.8 2.2 8.9 2.7 0.0 18.2 1.1 4.0 0.0 0.3 0.2 0.4 20.6 7.2 0.0 7.3 12.9 3.9 10.6 12.6 2.1 0.1 0.0 0.0 1.1 0.0 0.2 10.1 0.0 0.0 0.1 6.0 0.1 4.9 0.1 3.0 0.1 0.1 5.7 0.4 8.4 0.0 0.4 16.7 2.4 4.4 0.2 0.4 0.5 0.0 1.7 0.0 2.8 45.4 0.9 12.3 42.8 23.2 25.4 64.2 34.3 7.3 18.1 22.0 39.6 6.0 9.9 16.4 40.5 11.1 64.0 1.4 22.2 31.2 6.6 17.0 3.5 7.0 9.3 3.0 16.7 2.6 13.3 11.0 17.9 35.4 32.0 33.0 23.1 0.0 2.6 12.7 12.0 11.4 10.4 0.0 1.3 1.7 15.7 0.0 24.1 33.9 0.0 11.7 1.0 13.1 5.7 15.1 1.7 83.5 0.0 5.8 17.8 119.3 0.2 3.1 125.6 5.0 34.3 32.1 0.0 4.7 49.2 3.2 1.0 0.1 0.0 5.4 0.0 0.0 19.4 0.9 48.4 29.9 41.4 CASP10 MCH4 ENSG00000003400 "Caspase 10" Q92851 2 201182881-201229406 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.4" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 18.0" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" NA NA "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 16.0 3.3 3.4 10.1 3.4 14.9 7.6 1.9 3.3 7.0 17.7 4.4 4.3 18.6 8.3 8.2 10.4 4.9 7.2 4.8 3.6 3.0 10.3 7.8 14.2 10.4 4.1 1.4 3.4 6.1 1.4 2.1 8.5 4.7 5.0 11.9 4.1 6.9 6.9 3.6 5.4 42.4 4.8 5.6 26.1 8.7 2.1 2.5 17.1 6.8 8.2 17.9 9.4 6.1 7.8 6.0 4.7 15.4 7.1 7.1 5.8 2.9 2.4 0.1 0.2 0.1 0.2 5.2 0.5 3.5 0.3 1.4 3.1 6.9 0.2 5.0 1.8 1.2 2.0 0.1 1.6 0.9 1.4 3.3 8.4 2.5 10.4 1.2 5.6 9.1 0.3 1.4 3.8 0.3 0.2 18.0 3.6 10.0 12.4 0.3 0.1 10.7 5.2 0.3 4.1 1.5 5.9 0.3 12.4 6.3 4.2 0.1 0.1 2.8 0.1 1.4 2.3 0.1 5.3 7.3 0.2 0.5 2.4 0.1 13.5 8.0 0.3 3.4 4.3 0.1 4.7 9.6 0.6 6.2 13.5 5.2 7.8 5.2 3.4 5.3 5.0 7.1 6.0 1.9 7.1 15.4 6.0 1.0 5.8 3.4 3.4 1.9 3.3 3.6 3.0 4.1 1.4 4.7 2.5 17.9 7.7 16.2 2.5 5.4 0.0 1.7 7.6 14.7 5.7 8.7 0.0 0.9 1.7 11.0 0.8 24.0 35.4 23.3 9.2 0.6 3.7 3.0 7.0 5.8 8.1 0.0 2.4 20.9 21.0 0.0 0.6 16.1 6.8 11.8 18.2 0.5 8.3 24.6 0.0 6.8 0.3 0.0 2.1 0.0 0.0 4.0 0.3 13.1 11.0 7.9 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm NA NA Nucleoplasm "CAB012175: , HPA050678: AB_2681214" "unprognostic (6.96e-2)" "prognostic favorable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.5 6.5 6.6 10.7 6.7 26.8 10.2 9.6 10.9 9.6 8.5 9.0 8.2 8.2 10.8 7.8 14.1 8.4 5.7 6.1 5.7 4.1 7.3 5.8 9.8 15.8 6.9 6.1 8.7 8.1 12.1 6.6 11.3 7.3 7.6 10.2 10.1 11.6 5.8 4.3 14.2 14.0 7.4 6.3 18.6 7.5 8.6 6.9 45.7 8.9 8.0 23.0 7.4 10.2 18.5 11.8 33.2 17.7 13.4 21.4 7.6 10.9 10.3 11.6 20.5 6.5 7.7 6.2 11.2 5.1 10.3 11.3 10.2 12.4 20.8 10.7 7.1 7.9 10.8 11.6 8.9 13.8 18.2 8.9 12.3 16.2 7.0 3.5 23.9 15.4 5.3 7.3 12.5 4.4 4.7 8.8 16.4 10.2 13.3 10.9 10.8 41.6 25.2 14.6 10.7 10.5 30.6 6.0 12.7 6.1 9.3 12.7 14.3 22.3 9.7 7.1 8.3 10.6 9.2 9.8 9.2 6.4 16.5 11.2 11.1 10.9 24.2 10.3 28.5 16.7 33.2 10.8 9.3 14.9 11.9 14.6 15.8 20.6 15.4 9.8 18.5 15.4 17.8 12.3 13.4 17.7 11.8 21.4 7.6 6.6 6.7 9.6 10.9 5.7 4.1 6.9 6.1 7.3 6.9 8.9 8.8 17.9 5.4 13.5 4.7 5.3 25.5 2.7 3.4 7.0 7.9 16.2 3.3 7.7 35.5 13.9 6.5 0.0 6.6 12.8 8.7 5.5 9.3 4.4 8.8 6.4 10.3 14.7 15.4 38.5 10.9 12.1 20.3 11.8 10.3 4.0 7.6 3.5 7.8 3.3 14.0 0.0 8.4 10.1 29.4 12.0 4.8 20.8 13.3 6.0 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 76.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 76.7;eosinophil: 62.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.7" "Cell line enhanced" "Detected in all" "Karpas-707: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 310000 Mitochondria Nucleoplasm "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favorable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 20.7 11.6 10.8 16.9 10.5 16.7 10.0 22.3 9.2 10.4 25.4 12.8 12.5 32.3 13.9 11.5 22.8 8.9 12.0 8.8 10.0 8.8 10.6 18.7 12.4 23.6 10.2 8.5 8.3 10.0 4.6 13.6 29.4 9.7 8.8 20.9 8.2 13.0 10.0 12.6 9.5 49.7 9.3 12.6 26.5 18.7 6.4 10.9 44.7 7.8 13.5 24.3 16.2 11.0 4.2 5.2 76.7 10.6 9.2 9.9 7.0 8.3 4.7 18.7 8.9 11.6 15.5 10.8 25.3 19.2 17.8 10.3 8.5 7.1 11.7 4.0 12.3 8.4 7.2 14.8 9.0 20.3 30.0 8.1 18.7 3.7 19.7 13.9 15.2 17.8 21.1 11.0 11.3 9.1 12.8 22.0 12.1 15.4 74.2 18.3 3.6 24.0 14.2 18.5 9.3 5.9 17.4 8.8 11.3 15.3 13.8 10.7 11.7 10.9 10.0 14.2 19.4 5.4 9.9 14.9 8.1 7.5 6.0 11.7 34.5 32.3 8.0 9.9 10.6 11.5 76.7 4.2 62.8 5.5 6.8 5.7 4.2 5.1 7.8 5.2 3.1 3.9 5.8 5.8 9.2 10.6 4.1 9.9 7.0 10.8 10.5 22.3 9.2 10.0 8.8 10.2 8.5 9.7 10.9 17.9 12.0 18.6 18.8 43.3 17.6 14.1 5.1 25.4 20.5 12.2 0.0 41.4 11.6 16.0 7.6 23.3 28.6 0.0 20.9 27.1 16.9 14.4 17.3 12.9 20.5 12.7 17.3 20.9 25.1 3.2 6.9 17.5 28.7 55.9 34.1 13.8 20.4 19.9 7.1 6.5 10.2 12.9 14.4 7.5 14.2 25.0 43.0 36.2 21.5 31.5 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969436 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood: 82.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 10.6 6.3 0.5 9.7 0.5 6.1 9.4 0.0 0.0 4.7 3.5 8.9 3.5 5.9 14.1 5.8 7.3 4.9 0.5 0.5 6.7 16.5 14.0 10.5 1.0 7.5 16.8 0.0 3.0 10.7 5.8 4.0 11.2 1.9 1.6 10.4 8.8 4.3 2.0 19.0 8.2 0.2 4.2 11.3 8.2 8.0 20.5 29.3 82.8 43.2 29.6 35.7 46.8 6.4 2.1 0.0 2.8 13.7 31.4 5.3 11.0 21.6 17.8 25.0 5.3 29.1 3.3 23.8 14.3 21.5 10.7 0.0 19.1 17.0 3.8 0.1 8.6 1.6 13.9 33.8 8.7 4.2 28.5 28.6 21.2 29.7 21.3 30.9 0.1 0.2 0.0 13.5 0.6 5.0 10.2 0.0 14.4 6.3 3.8 4.1 2.9 14.9 10.2 0.1 0.0 10.2 7.2 10.1 0.2 2.9 12.7 16.0 18.8 6.5 16.5 7.7 0.0 0.0 0.0 9.6 19.8 13.1 14.9 39.1 7.0 31.5 43.2 34.6 20.5 24.2 30.1 29.3 20.0 14.8 22.0 82.8 29.6 33.5 4.9 35.7 46.8 56.6 57.5 87.2 53.6 49.6 0.0 3.6 40.8 72.3 54.6 21.0 0.0 113.8 13.3 118.8 0.5 68.8 12.0 0.0 164.0 65.7 45.5 29.4 33.5 26.8 101.8 0.0 20.1 65.1 148.5 1.3 27.0 95.5 28.7 63.1 28.2 1.9 153.2 9.9 19.4 30.9 0.1 6.5 22.7 0.2 0.6 40.1 96.9 117.6 17.5 68.0 CASP5 ICE(rel)III ENSG00000137757 "Caspase 5" P51878 11 104994235-105023168 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 22.3;intestine: 31.0;lymphoid tissue: 12.3" "Cell type enhanced" "Detected in some" 14 "Enterocytes: 12.9;Mucus-secreting cells: 5.2;Paneth cells: 10.5;Undifferentiated cells: 4.9" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.9;stomach cancer: 1.3" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 13 "intermediate monocyte: 10.5;neutrophil: 7.8;non-classical monocyte: 22.3" "Group enriched" "Detected in many" 14 "granulocytes: 7.8;monocytes: 22.3" "Cell line enriched" "Detected in some" 7 "HHSteC: 9.3" NA NA "unprognostic (4.30e-2)" "unprognostic (8.86e-2)" "unprognostic (1.07e-1)" "unprognostic (4.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.22e-2)" "unprognostic (9.90e-2)" "unprognostic (8.29e-3)" "unprognostic (1.47e-1)" "unprognostic (4.38e-3)" "unprognostic (7.39e-3)" "unprognostic (3.25e-1)" "unprognostic (1.82e-9)" "unprognostic (7.30e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" 0.6 0.3 0.3 11.8 1.0 0.0 0.3 0.2 0.8 0.2 13.3 0.2 0.0 8.2 0.2 0.2 0.3 0.5 0.1 0.4 2.9 0.3 0.4 1.2 2.7 10.5 0.4 0.2 0.2 0.3 0.0 0.9 0.5 2.0 0.4 11.3 0.2 0.3 0.0 0.8 0.2 31.0 1.4 2.1 12.3 0.4 0.3 0.3 0.3 0.3 0.3 0.1 0.9 0.3 0.0 1.0 7.8 22.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.9 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 9.3 0.0 0.0 0.3 1.2 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 10.5 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.8 0.0 22.3 0.3 0.0 0.6 0.3 1.0 0.2 0.8 2.9 0.3 0.4 0.2 2.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.0 12.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.7 0.7 0.0 2.4 0.0 0.0 5.2 0.0 0.2 10.5 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 4.9 0.0 CASP6 MCH2 ENSG00000138794 "Caspase 6" P55212 4 109688622-109703583 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 42.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003775, HPA011337, HPA024303" Enhanced Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "CAB003775: AB_562064, HPA011337: AB_1846053, HPA024303: AB_1846052" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.64e-5)" "unprognostic (1.45e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-3)" "unprognostic (9.87e-2)" "unprognostic (2.73e-2)" "unprognostic (2.59e-3)" "unprognostic (1.15e-2)" "unprognostic (6.78e-2)" "unprognostic (2.44e-1)" "unprognostic (8.74e-3)" "unprognostic (2.18e-1)" "unprognostic (2.41e-1)" "prognostic favorable (9.93e-4)" 8.1 6.1 3.6 6.7 4.3 5.3 14.3 2.8 3.8 6.9 25.5 2.8 4.5 23.4 5.9 4.3 8.7 5.3 11.7 4.9 4.0 2.0 11.0 14.3 5.6 8.5 5.0 1.6 7.0 13.0 2.3 6.4 4.3 4.5 8.1 19.5 3.4 8.0 10.3 3.4 6.5 42.8 14.0 6.6 9.1 9.2 2.7 4.3 14.5 11.2 3.3 8.4 8.2 12.7 4.4 8.0 8.5 7.0 5.6 21.3 8.0 12.6 4.1 8.5 7.7 6.2 6.1 12.6 7.1 4.9 6.4 6.9 6.8 26.1 1.3 8.3 7.3 8.9 5.9 10.1 11.2 5.1 20.1 6.6 11.1 3.7 6.0 5.0 11.1 7.9 6.7 8.4 6.1 1.5 8.6 12.1 15.1 14.4 39.6 10.3 7.1 28.7 7.0 6.5 8.7 7.5 10.0 5.4 6.9 21.0 12.0 9.0 6.7 7.5 13.6 4.2 10.7 5.8 4.1 10.2 7.1 7.5 3.4 8.0 5.8 10.5 1.4 9.2 13.4 3.6 8.5 5.3 6.3 4.9 4.8 5.3 4.1 17.8 9.3 6.0 4.4 21.3 11.8 1.1 5.6 7.0 8.0 16.4 8.0 3.6 4.3 2.8 3.8 4.0 2.0 5.0 1.6 4.5 4.3 14.9 13.4 8.5 9.5 9.6 5.2 3.3 30.6 25.4 20.5 19.2 5.9 16.7 8.3 35.9 2.0 9.2 52.0 0.0 40.5 34.0 12.1 6.6 9.3 17.8 17.1 0.0 56.7 6.2 8.6 1.6 11.8 8.5 1.7 25.2 48.2 12.8 42.5 56.1 9.2 26.3 1.3 6.5 6.9 1.7 8.3 10.2 4.8 12.8 64.3 7.8 CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 64.8" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 95.7;monocytes: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025563 Enhanced NA NA "CAB025563: " "prognostic favorable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" 16.5 7.8 8.6 12.3 8.7 3.4 22.1 4.7 11.3 13.3 35.5 5.9 9.8 30.8 12.6 6.1 12.0 9.5 7.8 9.0 7.6 3.9 14.1 15.7 16.2 12.2 7.3 2.7 11.0 18.4 5.7 9.6 10.2 9.1 11.9 28.5 5.8 21.8 10.5 9.7 10.9 64.8 9.3 12.4 12.3 21.0 4.3 8.0 12.0 8.4 8.1 11.3 10.6 36.6 9.6 8.6 14.6 17.1 5.4 12.2 7.4 11.0 12.0 9.8 5.2 18.0 15.9 6.8 12.9 20.1 23.1 28.9 8.9 19.3 11.8 7.7 11.7 8.6 9.8 12.1 9.7 16.3 18.2 16.3 7.6 8.9 14.9 12.1 8.1 10.1 10.3 6.5 13.1 5.4 10.3 30.4 11.3 2.0 16.1 8.5 15.0 19.1 6.3 1.7 12.5 7.3 19.6 40.0 7.0 18.3 8.2 0.8 5.9 9.9 14.4 6.8 9.8 17.1 7.2 14.6 5.1 9.9 5.4 10.6 11.9 7.4 0.3 5.2 15.2 5.8 14.6 12.5 9.4 9.6 17.1 8.4 9.6 8.3 12.2 8.6 7.3 6.5 8.7 2.1 5.4 14.0 1.1 11.1 7.4 8.6 8.7 4.7 11.3 7.6 3.9 7.3 2.7 9.1 8.0 8.9 10.5 14.3 19.4 17.5 0.6 2.2 15.3 32.1 19.4 21.0 0.0 10.1 10.0 37.1 0.2 17.1 95.7 23.3 34.0 21.2 17.6 27.4 12.7 14.7 15.3 0.0 9.2 12.9 13.3 0.0 8.9 18.5 6.8 108.2 66.5 7.6 35.7 66.6 3.9 19.2 1.6 19.4 12.8 1.0 26.0 12.9 9.2 15.8 32.0 27.1 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.5" "Cell type enhanced" "Detected in many" 5 "T-cells: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol No No Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535" "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favorable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 14.1 10.6 2.0 31.6 2.6 27.1 10.2 1.4 1.8 7.9 18.5 3.9 7.0 9.6 9.6 12.0 11.7 9.1 12.1 4.4 2.1 2.3 16.4 14.8 17.1 28.3 3.9 1.1 8.2 7.6 1.8 5.9 12.3 3.2 9.8 8.7 4.4 9.6 8.4 2.7 7.4 34.7 5.1 5.0 37.7 7.4 3.8 2.7 43.7 6.7 10.7 43.4 9.6 7.3 13.8 13.7 52.5 17.0 22.2 26.4 12.0 14.5 12.4 3.6 10.1 10.1 14.8 5.6 6.4 6.3 7.6 12.6 16.6 25.4 1.6 14.1 4.9 13.7 7.4 7.9 7.6 15.1 9.4 7.2 14.2 10.1 15.8 8.2 11.0 15.4 12.8 18.8 14.4 11.3 6.4 7.2 12.3 12.7 31.6 6.9 6.0 14.3 11.6 5.9 8.0 11.1 10.8 7.5 25.9 14.3 16.2 1.1 0.5 8.3 13.8 8.2 3.5 3.6 8.6 9.0 8.2 8.6 4.3 5.0 28.7 12.8 9.9 12.3 14.8 7.7 20.7 13.0 24.9 25.0 17.0 23.1 13.8 20.5 26.4 13.7 7.8 13.3 16.9 52.5 22.2 15.6 6.1 24.0 12.0 2.0 2.6 1.4 1.8 2.1 2.3 3.9 1.1 3.2 2.7 23.8 26.1 34.1 10.1 6.6 1.5 1.6 7.6 16.0 18.2 5.2 9.8 7.5 13.3 9.0 5.6 7.1 19.8 0.0 7.3 10.3 3.8 8.1 23.2 10.4 11.2 0.0 4.1 5.5 25.6 0.7 2.3 21.7 6.8 19.8 13.0 0.1 9.6 12.7 0.7 20.0 0.4 0.0 1.4 0.7 0.4 6.8 2.9 55.4 12.1 12.7 CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria NA NA Mitochondria "CAB004348: AB_673489, HPA001473: AB_1078401, HPA046488: AB_2679670" "prognostic favorable (5.91e-4)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (7.84e-2)" "unprognostic (1.93e-2)" "unprognostic (8.54e-3)" "unprognostic (1.90e-3)" "unprognostic (6.75e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.21e-2)" "unprognostic (5.48e-2)" "prognostic favorable (1.67e-5)" 7.4 24.1 7.8 8.2 9.3 8.9 5.5 11.1 8.7 8.3 9.3 10.2 18.9 5.2 11.9 16.5 7.5 13.4 29.1 10.2 8.3 7.2 11.6 9.4 10.8 12.6 10.7 4.3 33.4 29.0 15.6 18.5 14.7 8.8 10.2 6.4 8.7 6.6 19.0 8.2 2.8 13.3 7.8 9.0 11.0 6.7 14.4 7.1 6.2 14.8 7.2 14.6 7.3 8.1 11.2 11.7 23.3 11.2 13.0 5.1 6.1 7.2 10.6 4.1 7.2 9.5 4.7 3.8 5.3 7.0 7.9 10.2 7.4 8.8 10.6 12.5 7.2 10.2 2.6 7.0 5.6 9.2 3.7 8.7 7.6 23.6 7.4 8.8 7.3 8.9 6.5 10.4 12.1 3.7 7.8 8.5 9.6 17.0 9.9 4.7 3.7 2.5 8.3 4.1 10.5 5.9 4.9 10.4 12.3 9.8 4.2 3.6 6.9 7.6 1.8 12.6 9.5 4.5 5.3 3.3 10.6 4.8 11.4 3.5 9.6 14.4 12.0 8.1 8.0 3.5 22.7 11.2 23.3 5.1 8.2 3.7 9.6 3.0 3.6 11.7 11.2 1.7 2.6 16.0 13.0 7.9 5.2 2.8 6.1 7.8 9.3 11.1 8.7 8.3 7.2 10.7 4.3 8.8 7.1 3.0 3.0 4.7 7.9 2.6 3.2 6.7 5.1 10.7 9.1 17.4 5.9 15.4 1.7 6.6 9.9 3.0 6.8 0.0 7.8 9.0 5.0 4.5 1.1 4.3 8.5 4.8 2.9 3.7 4.3 4.1 2.0 8.7 0.0 3.6 5.6 6.5 7.9 5.8 3.5 4.2 6.2 0.0 9.9 15.8 5.7 2.0 29.9 4.9 4.5 5.4 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853230 "Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 94.9;seminal vesicle: 104.1" "Cell type enhanced" "Detected in many" 8 "Ciliated cells: 49.5;Erythroid cells: 46.7;granulocytes: 39.1;Kupffer cells: 31.1;T-cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 15.3" "Group enriched" "Detected in all" 4 "B-cells: 9.0;dendritic cells: 5.1;NK-cells: 15.3" "Cell line enhanced" "Detected in some" "Daudi: 50.8;Karpas-707: 14.2;MOLT-4: 12.8;REH: 10.3;U-266/70: 11.0;U-698: 9.6" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 4.1 3.3 3.8 17.6 8.5 9.3 2.6 0.7 12.0 1.0 3.2 10.4 14.6 4.3 0.7 0.9 2.3 2.4 1.5 5.0 4.0 4.2 1.2 5.4 4.7 16.1 4.9 3.1 0.6 0.7 0.0 2.5 0.6 3.1 10.8 2.7 4.4 2.8 104.1 14.2 0.5 6.2 0.9 1.8 20.6 2.0 0.7 2.5 94.9 2.8 2.0 13.2 7.6 0.9 9.0 5.1 1.3 2.2 15.3 2.3 3.7 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 50.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.1 14.2 0.0 0.0 12.8 3.1 0.0 0.0 0.0 10.3 0.0 8.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 2.2 0.2 0.0 0.0 0.0 0.0 11.0 0.1 9.6 0.1 2.4 0.1 0.0 1.7 0.0 1.1 2.2 0.3 9.0 1.4 1.2 4.1 6.6 2.3 1.8 1.3 15.3 1.4 5.1 2.1 3.7 3.8 8.5 0.7 6.2 4.0 4.2 4.9 3.1 3.1 2.5 3.0 10.8 23.4 0.4 0.0 0.0 0.8 0.0 49.5 18.2 0.0 9.8 0.2 0.0 0.0 1.6 0.1 0.0 46.7 0.0 0.0 0.5 10.7 39.1 1.3 4.6 0.0 0.0 3.1 31.1 0.0 0.0 10.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 2.2 1.4 0.0 0.5 30.5 0.7 0.1 CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20588948-20618908 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 126.5;bone marrow: 68.0" "Cell type enhanced" "Detected in many" 11 "Enterocytes: 120.2;Hepatocytes: 94.4;Kupffer cells: 118.1;Pancreatic endocrine cells: 70.1;Paneth cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 126.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 126.5" "Cell line enhanced" "Detected in many" "A-431: 42.9;CAPAN-2: 28.6;HeLa: 40.6;PC-3: 20.4;SiHa: 51.0;U-937: 18.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA064202 Enhanced Approved Nucleoplasm NA NA 3700000 Nucleoplasm "HPA064202: AB_2685211" "unprognostic (2.38e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" 4.0 1.4 1.5 4.0 1.5 68.0 2.2 1.1 2.4 19.0 8.6 1.7 2.0 2.6 6.7 3.5 38.3 2.9 1.8 5.9 1.7 1.6 12.5 42.1 8.4 9.1 2.0 1.3 2.9 0.8 1.2 0.7 30.8 3.5 4.2 10.2 4.5 6.9 1.5 3.2 7.0 24.7 4.3 1.9 11.8 1.2 2.9 0.9 0.9 3.0 23.3 10.5 3.1 16.5 0.0 1.3 126.5 21.7 0.0 0.1 7.1 42.9 4.2 0.0 0.0 0.0 1.3 0.0 3.3 0.9 0.8 3.4 0.2 28.6 0.0 1.6 6.8 1.8 15.1 0.8 11.2 2.2 0.0 0.8 0.0 40.6 5.4 0.3 0.0 0.0 1.9 1.8 8.1 0.0 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 5.0 20.4 0.0 0.0 0.4 0.1 0.0 0.0 0.0 51.0 0.0 0.0 0.5 0.0 1.2 0.7 0.0 1.7 3.9 0.2 0.0 0.0 0.0 0.5 18.0 0.0 16.3 21.7 43.3 0.0 11.4 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 126.5 0.0 9.3 0.2 0.0 7.1 1.5 1.5 1.1 2.4 1.7 1.6 2.0 1.3 3.5 0.9 3.0 1.4 0.9 0.2 1.3 0.1 2.8 2.5 0.0 0.0 5.2 0.0 0.2 36.5 2.4 0.6 4.4 120.2 0.0 1.3 2.7 1.0 0.9 0.0 94.4 6.1 0.0 0.0 28.8 118.1 0.8 0.3 3.7 0.0 0.0 12.5 0.0 70.1 48.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 2.1 1.5 4.9 0.3 CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Group enriched" "Detected in many" 6 "Early spermatids: 165.7;Late spermatids: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 30.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023783 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA Nucleoplasm "Nuclear bodies, Cytosol" "HPA023783: AB_1846352" "unprognostic (3.72e-2)" "unprognostic (2.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (1.54e-3)" "unprognostic (1.38e-1)" "unprognostic (9.27e-4)" "unprognostic (4.88e-3)" "unprognostic (6.30e-2)" "unprognostic (3.97e-3)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (6.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (6.66e-2)" 6.2 2.4 5.8 6.5 5.5 13.7 12.2 1.8 6.2 7.7 11.8 4.8 2.2 7.2 15.1 4.8 3.4 13.7 3.6 4.1 8.8 3.5 6.6 2.4 12.3 15.4 3.8 5.4 5.8 6.7 9.8 8.1 7.6 4.6 10.0 6.3 8.3 7.7 3.9 4.3 5.6 22.6 5.0 3.2 9.6 6.0 38.2 4.7 12.0 6.1 3.4 11.3 5.8 8.4 4.8 6.1 11.6 3.7 3.9 13.0 4.1 2.2 1.8 5.9 6.7 2.2 1.6 4.1 2.9 1.9 2.9 2.3 6.2 1.9 1.1 2.1 1.7 2.3 1.7 4.0 1.6 2.9 2.3 9.9 4.0 1.7 2.0 0.8 5.4 7.1 1.3 0.4 3.1 1.0 1.4 5.1 2.4 30.6 3.5 4.2 1.0 4.3 6.0 3.6 1.4 2.3 4.7 7.6 1.1 2.0 5.1 1.1 1.9 3.0 2.9 4.0 3.0 1.3 7.0 2.2 1.6 3.6 2.7 1.7 1.7 0.6 1.7 1.9 5.0 0.9 11.6 3.7 8.4 7.3 3.3 13.0 4.8 11.3 8.4 3.5 3.1 11.0 5.8 5.5 3.9 2.3 6.1 5.6 4.1 5.8 5.5 1.8 6.2 8.8 3.5 3.8 5.4 4.6 4.7 3.0 5.6 2.2 4.2 3.3 0.2 5.3 0.0 28.1 5.7 1.8 3.9 1.7 0.0 2.7 165.7 9.3 12.8 0.0 1.7 0.8 4.7 6.6 14.0 1.5 2.3 0.0 4.6 6.2 4.6 161.3 4.6 4.3 5.0 5.4 4.7 9.1 2.5 8.7 0.7 1.7 3.6 0.0 2.8 1.9 3.0 2.0 1.8 10.2 2.7 2.3 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619830 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 9.9" "Lineage enhanced" "Detected in many" "granulocytes: 9.9" "Cell line enhanced" "Detected in many" "ASC diff: 15.2;ASC TERT1: 22.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013312, HPA064747" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA013312: AB_1846354, HPA064747: AB_2732719" "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favorable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (7.40e-2)" 7.3 6.2 6.8 3.0 7.5 4.4 15.7 2.4 6.6 5.3 5.0 14.8 7.1 4.5 4.0 3.7 3.5 7.1 5.9 8.2 6.0 4.6 9.1 16.0 4.9 1.8 9.5 4.0 5.8 7.3 17.1 5.2 3.4 7.1 5.7 5.4 8.3 3.8 7.2 2.2 3.3 7.7 4.2 9.3 2.2 9.3 16.9 8.2 0.2 13.6 2.2 2.1 10.4 10.3 1.6 0.0 9.9 0.0 0.1 2.9 0.8 5.2 2.9 3.1 3.2 15.2 22.8 8.5 3.8 5.1 2.5 4.1 9.9 8.3 0.0 3.7 8.0 6.2 5.9 4.4 3.0 3.0 1.3 4.1 0.8 1.0 7.8 2.5 0.0 0.1 9.4 1.5 2.7 2.5 3.0 0.5 0.0 3.0 0.6 3.5 2.5 0.0 0.8 5.8 5.9 2.5 0.0 1.9 0.1 4.0 8.1 0.9 4.9 2.7 0.8 1.5 11.0 0.7 1.7 1.5 2.5 3.0 6.6 2.8 0.1 0.0 0.0 2.7 0.0 6.0 9.9 0.0 3.1 2.9 0.0 1.6 1.6 1.3 2.3 0.0 0.8 2.3 1.4 0.0 0.1 0.0 0.0 1.6 0.8 6.8 7.5 2.4 6.6 6.0 4.6 9.5 4.0 7.1 8.2 6.0 9.1 2.4 7.4 8.0 6.4 14.5 10.2 16.0 14.8 8.7 7.9 5.3 6.6 4.8 28.7 4.7 8.5 0.0 5.7 2.5 9.3 10.2 13.9 27.2 8.6 7.9 2.4 8.0 1.0 27.6 8.3 4.1 8.5 3.6 7.6 10.9 6.9 6.5 11.0 14.1 11.7 25.8 22.0 3.7 5.5 6.8 2.9 5.0 7.2 8.1 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188402 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 23.0;testis: 19.4" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 106.0" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.8 1.2 1.1 5.5 1.1 13.0 0.8 0.7 1.2 1.1 3.3 0.6 1.0 1.8 0.6 0.9 3.9 0.4 2.2 0.7 1.3 2.4 1.2 0.9 0.7 4.1 1.4 0.2 2.1 3.6 0.4 2.3 4.2 1.2 1.0 4.0 1.5 1.8 0.5 0.7 0.8 2.1 0.8 0.7 3.6 1.3 19.4 0.2 23.0 1.6 8.8 7.4 0.8 1.3 1.7 0.9 0.5 0.1 0.0 1.0 0.1 7.6 3.8 18.1 9.7 0.6 1.2 12.5 10.6 4.0 13.4 10.9 16.4 4.0 22.8 4.2 2.8 8.5 5.8 30.9 7.3 14.2 7.4 16.3 29.1 6.9 8.1 0.6 20.5 8.5 0.6 1.1 16.6 7.2 1.6 5.0 17.0 23.1 12.1 7.2 4.1 25.6 16.0 26.4 7.0 8.7 11.5 11.9 12.4 3.4 7.2 8.5 10.6 6.6 7.7 3.4 12.0 4.0 14.6 2.5 6.6 10.2 7.3 14.5 6.1 18.2 35.8 4.9 22.9 5.5 0.0 0.0 0.5 0.4 0.0 0.0 1.7 0.6 0.2 0.9 0.0 0.0 1.0 0.0 0.0 0.1 0.5 0.0 0.1 1.1 1.1 0.7 1.2 1.3 2.4 1.4 0.2 1.2 0.2 0.0 0.0 0.0 0.4 0.3 0.0 106.0 0.0 0.0 0.0 0.0 2.0 1.9 0.0 0.5 14.7 0.1 0.3 0.0 0.8 5.7 0.5 0.4 0.0 0.2 2.5 0.0 1.2 1.3 0.3 22.9 1.4 0.0 0.0 0.0 1.5 0.5 0.9 0.0 1.8 0.2 0.4 0.0 0.4 15.8 13.7 0.0 0.2 0.0 3.2 0.3 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 4.5;NK-cells: 9.3;T-cells: 15.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 12.1 8.7 15.1 27.7 23.3 26.0 28.8 49.6 21.1 13.0 14.7 12.8 4.6 14.9 17.0 10.3 11.7 13.0 18.6 7.5 15.7 12.5 13.3 11.0 33.0 42.8 21.9 12.5 17.3 5.7 7.5 21.0 30.3 13.8 11.0 12.0 7.7 7.4 10.2 6.2 19.8 16.8 14.8 14.7 24.5 14.1 6.3 22.3 33.3 18.7 20.8 31.6 15.3 16.3 4.5 1.3 1.5 1.8 9.3 15.5 5.9 29.0 62.7 8.4 13.9 10.3 10.1 4.2 14.4 21.6 24.1 18.0 10.9 42.1 20.3 6.2 14.7 59.6 42.5 11.3 23.9 11.4 7.8 12.2 10.9 20.1 13.1 41.2 8.4 5.6 9.9 19.2 22.3 26.4 8.2 13.3 10.2 7.0 53.5 14.2 23.3 26.3 12.3 6.2 19.9 26.8 13.8 23.8 14.5 16.4 2.7 6.0 13.1 34.1 32.6 16.7 7.5 11.0 4.4 11.0 12.9 15.7 23.4 19.0 13.1 20.6 8.2 6.6 8.3 12.4 1.5 1.4 0.0 13.6 1.8 12.7 3.5 13.6 13.7 1.3 4.5 11.4 13.2 0.1 9.3 0.9 0.7 15.5 5.9 15.1 23.3 49.6 21.1 15.7 12.5 21.9 12.5 13.8 22.3 8.9 23.7 9.0 5.5 10.0 13.9 6.8 7.6 0.0 3.4 7.0 2.0 5.3 0.0 7.8 0.5 24.0 3.8 23.3 4.2 14.2 13.6 4.7 1.1 11.6 24.4 3.2 7.5 12.9 11.6 1.0 6.6 10.6 16.9 5.4 7.9 8.3 10.4 2.9 8.5 9.4 2.4 0.0 11.3 1.0 11.5 9.8 3.0 25.4 3.5 3.4 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285265-138338355 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 23.3;testis: 22.3" "Group enriched" "Detected in some" 4 "Early spermatids: 32.9;Late spermatids: 35.1;Spermatocytes: 36.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 2.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 1.1 0.6 0.3 6.7 0.4 5.2 1.1 0.4 0.6 0.6 3.3 0.1 0.7 3.0 0.3 0.6 2.5 0.2 0.4 0.7 0.4 0.4 0.4 0.6 0.7 2.6 0.4 0.3 0.3 0.3 0.0 0.4 1.9 0.3 0.4 4.0 0.0 1.2 0.7 0.2 1.1 3.7 0.5 0.3 1.7 1.2 22.3 0.2 23.3 0.3 1.8 5.0 0.6 0.9 1.0 0.1 0.7 0.0 2.1 2.7 0.5 13.3 5.6 18.8 14.5 0.4 1.9 4.7 8.1 8.7 18.4 25.4 13.5 26.0 6.2 6.8 4.9 20.2 7.3 15.5 12.4 17.8 5.1 10.6 4.7 7.6 10.0 0.1 3.2 4.9 0.4 0.5 10.9 9.0 1.9 11.8 13.5 6.9 12.3 11.2 7.4 8.7 8.1 4.8 10.6 6.1 5.7 17.2 7.3 3.2 4.1 9.5 5.9 18.1 5.5 8.6 17.3 9.2 6.7 3.5 10.2 8.6 7.0 12.9 7.5 6.1 6.1 4.0 6.8 7.7 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.5 0.3 0.0 0.2 0.0 0.0 0.7 2.1 0.0 0.1 2.7 0.5 0.3 0.4 0.4 0.6 0.4 0.4 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 32.9 0.0 0.3 0.0 0.0 5.7 0.2 0.3 0.0 0.2 2.2 0.0 0.0 0.0 0.3 35.1 1.7 1.2 0.0 1.0 0.6 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 36.3 8.3 0.4 1.1 0.0 1.6 0.1 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 80.3" "Cell type enriched" "Detected in many" 4 "Early spermatids: 2056.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 16.1" "Group enriched" "Detected in all" 5 "NK-cells: 5.8;T-cells: 16.1" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 2.4 1.0 1.6 6.5 1.7 12.8 1.5 1.5 2.5 1.0 4.5 0.2 0.2 3.8 0.9 1.1 4.4 0.7 0.9 3.0 1.4 1.9 1.0 1.1 1.1 8.8 1.7 1.9 0.9 0.7 0.0 1.0 2.3 2.8 0.9 5.8 0.9 1.7 0.1 3.9 1.8 4.0 2.2 1.0 2.3 1.8 80.3 0.3 18.3 1.1 6.4 9.5 2.1 1.8 2.0 1.6 1.1 1.4 5.8 16.1 2.9 55.2 21.2 16.3 16.3 2.7 3.3 9.4 13.2 19.5 28.2 31.2 16.0 27.6 27.2 9.7 20.6 29.7 40.7 24.7 16.0 52.7 32.6 11.9 13.8 15.3 26.4 2.0 17.2 9.8 1.2 1.0 17.6 30.7 9.9 17.9 26.4 6.9 34.8 33.8 39.3 23.8 14.0 5.7 54.1 46.0 14.8 14.4 5.9 14.9 12.1 6.7 8.5 24.2 14.3 10.5 12.8 29.6 14.7 6.5 12.5 42.9 19.7 31.2 8.4 9.7 18.7 20.9 24.9 22.8 0.0 1.3 1.1 1.2 1.4 0.6 2.0 5.2 4.3 1.6 0.9 2.7 2.2 0.9 5.8 0.9 1.2 16.1 2.9 1.6 1.7 1.5 2.5 1.4 1.9 1.7 1.9 2.8 0.3 0.0 0.0 0.8 3.1 8.2 1.4 9.3 0.0 0.0 1.2 1.8 2.0 9.8 0.0 2.8 2056.4 2.0 2.9 256.9 2.1 27.0 6.6 2.2 6.9 1.8 31.5 4.8 7.5 4.9 7.5 483.1 19.8 5.7 1.7 3.6 6.2 1.2 2.0 6.2 9.9 1.7 2.3 0.0 2.1 159.2 36.4 5.6 3.4 7.0 12.8 1.4 CELA1 ELA1 ENSG00000139610 "Chymotrypsin like elastase family member 1" Q9UNI1 12 51328443-51346679 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 6.3;blood: 12.6;pancreas: 11.8" "Group enriched" "Detected in some" 6 "Exocrine glandular cells: 15.1;Kupffer cells: 7.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Cell type enhanced" "Detected in many" "basophil: 9.0;naive CD4 T-cell: 12.6" "Group enriched" "Detected in many" 7 "granulocytes: 9.0;T-cells: 12.6" "Cell line enriched" "Detected in some" 4 "BEWO: 11.0" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "unprognostic (3.54e-2)" "unprognostic (1.64e-1)" "unprognostic (4.73e-2)" "unprognostic (2.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.59e-2)" "unprognostic (3.83e-3)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" 0.0 6.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.0 11.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.9 9.0 1.6 0.2 12.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 9.0 1.6 0.1 1.1 0.8 0.4 0.3 2.7 0.8 0.9 0.0 12.6 5.9 0.2 0.2 0.9 0.0 0.3 1.3 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 1.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.0 CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase family member 2A" P08217 1 15456728-15472091 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1559 "pancreas: 2376.3" "Cell type enriched" "Detected in some" 19 "Exocrine glandular cells: 6761.1" "Cancer enriched" "Detected in single" 3819 "pancreatic cancer: 463.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "neutrophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;HEL: 1.2;HL-60: 1.0;HMC-1: 5.0;K-562: 1.1;U-2 OS: 1.6" "Secreted to digestive system" NA NA "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.8 2376.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 1.2 0.0 0.0 0.0 1.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.0 6761.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.1 0.0 0.0 361.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase family member 2B" P08218 1 15465909-15491400 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 188 "pancreas: 697.9" "Cell type enriched" "Detected in some" 42 "Exocrine glandular cells: 1081.3" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 3.7;neutrophil: 1.2" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.7" "Cell line enriched" "Detected in some" 5 "U-138 MG: 9.3" "Secreted to digestive system" NA NA "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 697.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.7 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.7 1.0 1.8 0.7 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.2 1.1 0.0 0.0 0.0 0.0 0.4 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.5 0.4 0.0 0.0 9.3 0.0 0.0 0.0 0.9 0.1 0.3 0.4 0.0 0.0 3.7 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1081.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase family member 3A" P09093 1 22001656-22012539 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2051 "pancreas: 2541.2" "Cell type enriched" "Detected in some" 31 "Exocrine glandular cells: 30160.2" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "MOLT-4: 21.6" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 2541.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 29.3 0.0 0.0 0.0 30160.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.8 0.3 0.0 0.0 164.1 0.0 0.0 964.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase family member 3B" P08861 1 21977021-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 196 "pancreas: 1614.4" "Cell type enriched" "Detected in some" 24 "Exocrine glandular cells: 12399.8" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1614.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.9 5.3 8.2 3.0 2.3 3.2 0.9 0.6 5.0 1.7 1.3 2.5 1.5 2.2 1.2 1.8 1.8 1.7 5.4 2.7 5.5 2.7 1.5 2.2 1.6 1.0 0.5 0.0 2.5 4.1 2.4 4.9 4.0 1.3 1.9 3.2 2.3 2.4 1.5 0.0 2.7 2.5 3.6 2.5 5.6 0.4 2.6 2.2 1.5 1.4 0.9 3.5 3.6 0.9 4.3 0.0 3.6 3.2 1.8 3.5 0.8 0.3 3.7 2.6 2.8 3.7 2.9 1.6 2.3 1.0 4.9 4.8 2.5 1.9 4.8 0.6 5.1 2.5 1.8 3.1 3.0 2.0 3.7 2.2 2.8 1.4 5.9 3.2 3.0 8.2 2.3 1.7 5.3 2.9 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 65.6 0.0 4.9 0.0 12399.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.0 0.9 0.0 0.0 105.6 0.0 0.0 510.5 7.0 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.0 CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronan binding protein" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 33.9;lymphoid tissue: 116.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 2.5;Club cells: 7.9;Cone photoreceptor cells: 5.9;Fibroblasts: 7.2;Horizontal cells: 3.2;Intestinal endocrine cells: 4.6;Rod photoreceptor cells: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 42.9;BJ hTERT+: 67.9;fHDF/TERT166: 53.9;HSkMC: 37.1;hTERT-RPE1: 40.5;U-138 MG: 19.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 560000 "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.65e-4)" 6.7 2.1 1.7 11.6 5.0 1.7 1.0 6.8 8.9 2.4 6.9 6.4 2.6 1.2 33.9 7.8 7.1 7.0 2.8 6.4 2.2 2.8 1.1 1.0 16.6 116.9 14.1 9.4 5.3 1.4 0.7 9.1 2.9 15.6 2.5 2.4 15.4 5.9 3.2 4.3 6.2 1.6 0.9 13.6 2.0 1.3 3.3 1.1 0.0 4.4 0.7 5.0 6.5 3.1 0.9 1.5 0.6 0.5 0.2 1.3 0.2 0.1 1.6 0.3 0.2 0.1 0.6 0.2 42.9 67.9 1.1 0.9 0.5 0.2 0.2 0.1 53.9 0.2 1.0 0.0 0.1 0.2 0.1 0.4 0.1 0.2 3.5 0.4 0.1 0.2 37.1 0.0 8.4 0.0 40.5 0.0 0.2 0.2 0.1 1.0 0.9 0.1 0.1 0.2 14.2 1.9 0.2 0.0 0.1 0.0 0.7 2.7 0.1 0.7 0.1 3.6 0.6 0.2 0.0 0.2 19.6 0.1 1.4 0.7 0.1 0.1 0.2 2.1 0.3 1.3 0.0 0.3 0.0 0.4 0.4 0.1 0.6 0.0 0.2 0.0 0.9 0.0 0.7 0.6 0.2 0.5 1.5 1.3 0.2 1.7 5.0 6.8 8.9 2.2 2.8 14.1 9.4 15.6 1.1 0.0 1.0 0.0 0.4 0.0 2.5 0.8 0.0 0.0 7.9 0.0 5.9 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.1 7.2 0.8 1.1 0.0 0.3 3.2 4.6 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.5 0.8 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.4 0.9 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 355.0" "Group enriched" "Detected in many" 7 "Cholangiocytes: 565.6;Hepatocytes: 2145.0" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "classical monocyte: 32.6;myeloid DC: 32.9" "Group enriched" "Detected in many" 20 "dendritic cells: 32.9;monocytes: 32.6" "Group enriched" "Detected in some" 5 "Hep G2: 96.2;THP-1: 103.6" "Not detected" "Not detected" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 27.1 1.7 0.3 0.5 0.4 2.1 24.7 0.4 0.6 3.1 8.9 0.5 1.5 2.4 7.3 2.1 4.5 6.7 57.7 8.1 0.3 0.0 0.7 355.0 19.8 2.3 0.3 0.6 3.9 1.3 0.0 0.8 1.1 0.6 11.2 1.0 3.8 3.9 4.0 1.6 1.4 3.5 10.2 0.7 4.4 7.0 1.0 0.3 0.4 1.7 2.3 1.5 8.2 16.1 0.2 32.9 0.2 32.6 0.1 1.6 12.1 0.0 0.6 0.0 0.0 14.4 0.0 0.4 0.0 0.0 0.0 0.0 6.7 0.0 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 96.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 103.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 20.8 0.0 0.0 32.6 0.1 1.3 1.8 0.5 0.2 0.2 1.6 32.9 0.2 0.2 0.4 0.2 0.1 0.4 1.7 0.1 12.1 0.3 0.4 0.4 0.6 0.3 0.0 0.3 0.6 0.6 0.3 14.9 74.9 21.0 2.5 14.8 0.0 0.6 565.6 202.1 28.4 15.7 0.0 0.4 0.0 16.2 77.2 1.5 0.0 70.0 17.2 0.8 45.8 1.1 5.8 2145.0 18.9 0.0 36.2 43.0 88.2 134.3 17.3 20.4 37.1 0.0 0.0 8.3 0.9 0.2 93.0 0.5 0.5 0.0 7.2 0.9 1.0 10.2 0.7 20.3 0.0 1.7 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "esophagus: 46.7;intestine: 146.9;liver: 78.6" "Group enriched" "Detected in many" 4 "Enterocytes: 912.6;Hepatocytes: 449.6;Paneth cells: 448.9;Undifferentiated cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA018897 Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 7500000 "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558" "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 5.8 15.3 8.5 8.8 11.7 2.4 5.1 13.0 15.9 9.5 42.3 12.1 11.2 146.9 7.0 11.9 46.7 6.1 14.5 15.2 7.4 6.6 22.5 78.6 6.7 4.6 8.2 10.7 8.4 12.0 10.0 6.8 7.3 10.3 9.7 42.6 13.0 12.7 7.9 11.6 8.9 117.3 10.4 5.6 7.8 10.9 8.5 8.2 9.0 11.7 14.1 12.1 7.6 11.6 6.9 8.9 5.0 10.6 7.9 10.7 5.2 6.9 9.1 9.6 12.8 9.5 8.9 7.3 7.9 12.8 9.3 11.9 9.8 11.5 8.1 7.9 10.3 7.0 18.0 7.0 19.9 7.3 7.2 9.7 7.9 5.2 18.4 13.4 10.4 14.0 12.9 37.7 13.2 22.1 11.5 6.9 5.7 11.1 6.0 15.7 4.4 9.3 8.7 5.2 7.5 9.2 11.0 9.7 9.5 26.4 12.1 6.2 8.2 25.8 6.5 6.7 3.9 11.2 12.9 8.5 12.3 6.5 7.6 5.9 12.0 14.3 9.6 18.9 8.2 9.2 4.7 10.4 4.7 10.1 7.8 9.2 6.1 7.7 10.7 8.9 6.9 9.5 8.6 5.0 7.9 10.6 7.7 6.8 5.2 8.5 11.7 13.0 15.9 7.4 6.6 8.2 10.7 10.3 8.2 29.8 24.0 25.9 13.7 17.3 28.5 25.4 137.6 42.8 12.5 50.6 19.6 13.0 31.5 21.9 1.5 9.8 912.6 0.0 29.5 5.6 12.7 14.5 27.6 449.6 16.6 27.0 23.2 25.2 27.6 1.3 17.3 13.9 10.1 5.4 141.3 17.6 37.9 448.9 17.0 124.1 22.7 32.3 11.3 42.6 10.2 17.9 11.3 18.7 459.3 15.2 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961237-66975148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;liver: 26.7" "Group enriched" "Detected in many" 5 "Enterocytes: 66.2;Hepatocytes: 40.9;Intestinal endocrine cells: 18.9;Mucus-secreting cells: 31.1;Paneth cells: 60.4;Undifferentiated cells: 31.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 8.1;Daudi: 8.9;JURKAT: 14.6;U-937: 7.6" "Not detected" "Not detected" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.5 0.1 0.8 13.3 1.3 0.2 1.0 1.6 1.3 0.6 40.7 0.7 1.4 16.8 0.4 0.7 2.2 1.5 3.0 0.7 1.5 1.0 6.8 26.7 0.9 0.2 0.8 1.1 0.5 7.8 0.0 1.1 0.4 2.2 0.4 17.9 1.1 5.9 0.6 12.9 0.5 41.8 0.5 0.9 0.2 4.6 0.9 0.6 0.5 0.4 2.4 0.5 0.4 0.3 0.7 0.6 2.7 0.6 0.3 0.9 0.2 0.4 3.2 0.4 8.1 0.3 0.2 1.3 0.3 0.2 0.4 0.5 0.5 4.0 8.9 2.7 0.0 0.2 0.7 1.2 0.6 0.1 1.5 6.0 4.4 1.3 2.6 0.1 1.0 0.7 0.3 1.0 0.9 0.2 0.3 0.0 14.6 2.8 1.9 0.3 1.2 1.5 1.6 1.4 2.7 0.5 1.4 0.7 1.4 0.1 0.5 0.4 0.9 0.2 6.1 0.2 0.7 5.4 6.8 0.4 0.4 2.6 0.7 0.2 1.0 3.6 1.3 0.3 7.6 0.2 0.6 0.6 2.7 0.3 0.3 0.5 0.5 0.6 0.4 0.6 0.7 0.9 0.6 2.0 0.3 0.4 0.3 0.9 0.2 0.8 1.3 1.6 1.3 1.5 1.0 0.8 1.1 2.2 0.6 3.0 7.0 0.8 0.0 0.5 0.0 1.0 5.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 66.2 0.0 0.8 0.0 0.0 0.2 1.1 40.9 0.2 0.0 18.9 0.0 3.2 2.6 0.0 1.4 0.0 0.0 31.1 0.2 1.0 60.4 1.1 8.2 0.0 0.0 0.0 0.6 1.3 0.3 0.0 0.0 31.9 0.1 CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 43.4" "Group enriched" "Detected in some" 4 "Cholangiocytes: 2.5;Collecting duct cells: 5.2;Hepatocytes: 5.5" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "U-266/70: 13.3" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" 0.1 0.1 0.7 0.1 0.6 0.0 0.1 0.1 0.8 0.1 0.1 0.1 3.6 0.0 0.1 43.4 0.1 0.0 1.4 0.1 0.8 0.5 0.1 6.6 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 1.2 0.3 0.1 1.2 0.1 0.1 1.8 0.1 0.0 1.7 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.8 0.8 0.5 1.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 461.5" "Group enriched" "Detected in many" 8 "Ductal cells: 523.0;Exocrine glandular cells: 173.6;Hepatocytes: 158.3;Pancreatic endocrine cells: 492.1" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 6.1;ASC TERT1: 6.0;CAPAN-2: 7.1;EFO-21: 5.3;fHDF/TERT166: 11.6;HSkMC: 19.1" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 180000000000 "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 9.3 1.0 0.3 4.1 0.4 0.3 2.4 0.2 0.4 1.3 9.0 0.4 0.9 3.2 0.5 3.7 2.2 4.0 8.9 3.3 0.2 0.0 16.1 461.5 2.5 2.1 0.7 0.1 2.8 5.8 0.4 1.0 4.0 1.0 4.0 1.6 2.6 3.1 0.3 0.5 0.5 4.7 2.6 0.6 0.8 4.1 1.4 0.3 0.3 1.8 0.5 1.7 1.6 0.4 0.1 1.6 0.0 0.8 0.0 0.2 0.0 0.0 1.8 0.1 0.1 6.1 6.0 0.0 0.0 0.3 1.6 0.6 0.0 7.1 0.1 5.3 11.6 0.3 0.0 0.0 1.9 1.4 0.4 0.3 0.4 0.3 0.6 0.0 0.7 0.1 19.1 0.1 0.9 0.6 0.6 0.2 0.1 0.2 0.7 0.1 0.1 0.1 0.4 0.3 0.0 0.1 0.2 0.4 0.2 1.7 0.0 0.0 0.0 0.6 1.2 0.2 0.0 0.0 0.2 0.0 0.2 0.5 0.3 0.4 0.6 1.9 0.5 3.2 0.6 0.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 0.4 0.2 0.3 0.2 0.0 0.7 0.1 1.0 0.3 0.0 20.0 14.0 0.7 0.7 0.1 0.4 20.4 24.1 40.9 5.2 0.0 0.0 3.3 523.0 0.0 2.4 5.0 0.0 173.6 0.1 6.0 9.0 0.0 158.3 0.8 0.0 2.4 11.6 13.2 0.0 2.6 1.2 0.0 31.5 6.7 0.8 492.1 11.8 0.0 11.2 0.7 0.0 3.8 0.1 0.0 1.6 1.4 1.9 11.2 1.8 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859643-863630 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Fibroblasts: 1885.6;Leydig cells: 4659.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 125.0" "Group enriched" "Detected in some" 5 "ASC diff: 40.8;THP-1: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 732000000 8000000000 "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 161.3 4.6 0.0 16.4 0.0 5.6 96.7 0.0 1.7 44.2 35.2 0.2 42.2 10.9 8.9 89.8 54.1 15.6 59.0 102.0 0.0 0.0 1.9 2.3 34.0 6.2 0.0 0.0 13.7 6.0 1.7 0.1 20.2 0.1 102.0 4.3 3.4 22.7 15.1 40.5 35.8 16.5 97.3 0.1 3.7 19.7 33.6 0.0 0.8 52.6 55.6 9.0 83.7 130.3 0.6 5.6 125.0 25.8 0.1 1.0 10.4 0.7 1.9 0.0 0.3 40.8 6.4 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.6 0.2 0.0 0.0 1.1 2.9 0.0 1.8 0.6 0.6 0.3 1.0 6.4 0.0 0.0 0.0 0.1 0.0 0.7 2.3 0.1 0.0 0.9 0.0 9.2 0.1 0.7 2.9 0.2 0.0 0.9 0.0 0.1 0.3 0.3 0.8 0.2 0.0 0.1 1.2 57.8 0.0 0.0 0.9 0.4 0.1 1.7 0.7 0.0 0.0 3.4 0.0 125.0 18.2 58.8 0.7 20.1 1.0 0.6 0.5 0.9 5.6 0.2 0.7 0.8 43.2 0.1 25.8 0.5 0.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.9 35.0 13.4 57.2 697.8 3.1 53.7 12.7 21.4 23.9 17.4 2.0 31.1 10.0 6.7 18.8 25.9 9.3 0.0 0.0 35.1 1885.6 17.4 16.2 1.3 255.2 1.6 4.1 49.7 345.8 28.7 4659.7 242.8 609.0 5.4 7.5 1.2 1.9 32.5 266.2 2.5 6.3 0.0 277.1 11.8 20.4 643.3 28.7 9.2 18.5 172.1 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109802179 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease mutation, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 90.7;liver: 198.4" "Cell type enhanced" "Detected in many" 18 "Hepatocytes: 510.3;Muller glia cells: 130.7;Proximal tubular cells: 205.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 29.5;Hep G2: 46.8;HSkMC: 19.5;RPTEC TERT1: 52.4" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 11000000000 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 9.5 13.2 1.5 2.3 1.4 0.0 3.9 0.9 2.5 5.0 4.1 1.1 2.9 4.9 5.0 12.0 4.4 9.7 9.3 6.2 1.6 0.8 90.7 198.4 7.2 3.1 1.8 0.7 10.6 7.6 0.5 3.8 3.2 2.6 3.9 0.7 6.8 3.6 3.6 1.4 0.5 4.6 3.0 3.0 7.8 1.7 3.6 1.6 0.5 5.3 2.3 1.4 3.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 29.5 0.0 9.4 0.1 0.2 0.0 0.0 0.0 0.0 9.9 0.3 0.0 0.1 46.8 2.0 0.0 0.0 19.5 0.0 0.0 0.0 1.3 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.4 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.4 0.9 2.5 1.6 0.8 1.8 0.7 2.6 1.6 11.9 34.5 6.7 10.2 0.9 2.4 1.9 107.0 2.7 36.4 61.1 2.0 0.1 26.6 36.3 0.2 49.6 1.1 0.0 27.7 0.1 3.8 1.7 3.5 510.3 0.6 1.6 0.0 54.6 14.3 0.2 15.5 1.7 0.0 2.8 0.7 130.7 34.8 2.9 0.0 205.0 5.6 0.0 3.2 0.7 0.5 1.0 0.2 4.4 0.6 10.3 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "Cystic fibrosis transmembrane conductance regulator" P13569 7 117465784-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 103.0" "Cell type enriched" "Detected in many" 5 "Ductal cells: 325.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "CACO-2: 12.8;MOLT-4: 48.1;U-266/70: 26.3" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 5 "olfactory region: 6.3" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.2 0.4 10.5 0.4 0.0 0.3 0.3 0.3 2.5 19.8 0.1 0.8 10.5 0.6 2.1 0.4 0.4 15.8 0.3 0.4 0.3 1.1 1.4 5.7 0.1 0.5 0.1 0.3 103.0 0.0 0.3 0.1 0.1 1.5 12.5 0.1 22.4 0.1 0.3 1.1 24.2 0.3 0.7 0.3 0.6 0.9 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.4 0.3 0.5 0.1 0.1 0.1 6.0 48.7 0.0 1.7 0.0 0.4 1.2 43.3 9.4 23.9 0.0 0.0 0.0 0.0 325.5 2.9 0.0 19.4 0.0 3.7 0.0 0.1 3.6 1.1 0.2 0.0 0.0 6.9 0.0 0.0 1.6 0.3 0.0 0.0 11.8 11.5 0.6 21.5 37.7 0.0 0.0 0.0 0.0 0.3 1.8 0.4 0.0 0.0 0.0 64.4 3.9 CHD1 ENSG00000153922 "Chromodomain helicase DNA binding protein 1" O14646 5 98853985-98928957 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022236 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoplasm, Nucleoli fibrillar center" "HPA022236: AB_2670915" "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (1.09e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (7.15e-2)" "unprognostic (6.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.88e-1)" "unprognostic (4.94e-2)" "unprognostic (3.15e-1)" "prognostic unfavorable (7.25e-6)" "unprognostic (2.69e-1)" "unprognostic (3.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.17e-1)" 13.0 7.4 5.5 15.8 7.5 41.7 10.2 14.9 5.5 9.4 9.3 4.7 7.9 6.6 11.3 7.5 7.6 10.8 10.6 6.8 4.9 3.1 7.3 10.1 12.1 8.8 8.8 3.2 18.1 8.3 9.3 12.0 11.1 6.4 7.7 7.4 5.6 8.1 11.5 13.2 8.2 12.3 8.3 7.2 17.2 8.6 12.0 7.4 70.1 8.1 5.5 9.3 10.4 11.3 10.1 7.1 16.7 8.2 8.1 8.4 2.2 11.0 10.2 23.9 16.2 8.1 8.4 20.9 11.5 7.5 9.3 12.2 12.6 8.6 9.4 11.2 6.6 15.2 9.2 18.7 12.6 19.5 14.7 14.1 16.6 12.1 9.6 8.9 15.9 12.9 7.2 5.2 16.2 16.4 6.3 11.2 30.8 20.0 14.5 9.3 8.9 31.6 6.9 16.0 3.5 12.4 26.9 16.7 14.0 8.2 10.6 11.2 9.6 14.7 7.7 18.6 13.0 7.5 11.0 12.7 20.1 10.8 12.5 20.2 10.1 10.6 19.9 11.0 16.0 12.0 11.4 8.2 10.7 6.5 7.5 8.2 10.1 6.1 6.1 7.1 9.4 8.4 6.6 16.7 8.1 7.1 5.2 6.3 2.2 5.5 7.5 14.9 5.5 4.9 3.1 8.8 3.2 6.4 7.4 44.7 61.6 41.0 98.1 138.2 37.4 25.7 20.4 61.6 79.6 34.9 41.2 44.3 6.6 31.7 85.6 50.1 37.2 0.0 27.6 32.9 75.7 63.5 85.6 26.0 30.8 31.8 30.5 36.2 71.6 14.8 30.0 68.0 64.1 52.3 28.7 17.0 29.9 35.1 18.0 11.0 50.1 45.3 96.8 51.7 52.7 164.7 75.5 54.3 26.9 58.2 CHD1L ALC1 ENSG00000131778 "Chromodomain helicase DNA binding protein 1 like" Q86WJ1 1 147242641-147295766 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027789, HPA028670" Enhanced Supported Nucleoplasm NA NA Nucleoplasm "HPA027789: AB_10601099, HPA028670: AB_10601257" "unprognostic (1.07e-1)" "unprognostic (3.93e-2)" "unprognostic (1.97e-1)" "unprognostic (3.49e-1)" "unprognostic (1.78e-1)" "unprognostic (2.58e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.86e-2)" "unprognostic (7.83e-2)" "unprognostic (1.39e-2)" "unprognostic (4.97e-2)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.31e-9)" "unprognostic (5.51e-2)" "unprognostic (3.52e-1)" "unprognostic (2.74e-2)" "unprognostic (1.16e-1)" 11.2 12.2 16.1 14.1 16.5 26.9 18.2 23.0 20.0 9.8 16.1 29.5 6.4 18.4 16.0 12.2 10.4 13.4 12.5 9.2 17.3 13.6 11.8 26.1 13.7 16.1 27.3 12.6 9.5 18.5 12.6 17.9 11.8 18.2 13.2 20.0 11.6 9.5 11.9 12.0 15.9 20.9 18.4 24.7 21.3 12.9 27.8 22.2 18.5 8.9 9.4 16.9 8.5 11.9 15.3 19.0 7.6 8.3 8.2 9.1 9.0 19.0 16.5 18.9 12.0 13.3 13.0 15.7 17.1 14.5 16.0 15.1 15.9 13.3 24.8 8.0 17.1 9.8 18.1 16.0 18.6 14.2 24.6 22.4 23.8 13.2 40.5 14.1 30.6 15.3 12.1 9.2 15.8 18.2 13.8 17.5 26.2 27.1 11.6 19.4 21.1 23.2 16.5 24.9 33.1 21.8 26.0 17.5 19.5 15.1 13.6 11.4 19.3 15.4 19.4 14.9 26.1 10.6 44.6 15.9 10.8 16.5 9.7 26.6 10.0 13.8 20.5 22.0 13.5 16.3 7.6 8.1 3.7 9.0 6.8 9.1 12.5 7.9 7.8 19.0 15.3 8.0 8.9 0.8 8.2 8.3 15.8 5.5 9.0 16.1 16.5 23.0 20.0 17.3 13.6 27.3 12.6 18.2 22.2 11.9 17.0 17.4 7.7 10.2 6.5 5.9 15.3 14.7 19.4 5.2 5.9 18.4 18.3 9.2 15.1 12.7 11.7 23.3 7.1 15.4 11.0 9.8 20.8 27.6 18.8 1.6 8.6 3.7 19.8 18.3 6.6 19.1 15.1 13.6 14.8 13.5 9.0 14.0 10.6 11.2 8.8 6.5 10.2 31.2 27.2 9.2 9.8 10.7 18.0 5.8 CHD2 "DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614" ENSG00000173575 "Chromodomain helicase DNA binding protein 2" O14647 15 92900189-93028005 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060744, HPA060960" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "HPA060744: AB_2684353, HPA060960: AB_2684398" "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (2.14e-2)" "unprognostic (5.98e-2)" "unprognostic (2.12e-2)" "unprognostic (3.10e-2)" "unprognostic (2.67e-2)" "unprognostic (7.85e-2)" "unprognostic (7.51e-3)" "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (1.79e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" 23.7 16.6 18.7 23.6 21.1 66.7 21.8 35.1 22.8 24.1 19.9 19.7 17.6 15.7 26.1 31.9 20.3 18.4 16.8 15.3 18.5 15.7 17.7 17.6 30.4 25.2 22.1 13.9 26.3 20.9 27.5 41.9 33.1 19.1 22.4 16.1 22.1 21.2 19.9 24.3 25.2 24.3 20.3 30.8 26.9 20.8 20.4 22.4 39.5 28.8 11.3 37.4 34.7 19.0 25.5 17.2 34.5 6.3 8.0 17.5 4.6 10.7 5.9 16.0 7.0 10.0 24.6 12.3 10.1 10.4 6.8 8.5 7.5 14.2 2.6 8.5 8.8 11.7 16.1 9.3 10.0 9.6 0.0 5.5 12.8 11.8 6.4 13.4 13.5 10.1 15.5 12.3 8.1 16.6 14.2 11.6 19.1 13.3 30.4 10.3 6.6 7.0 7.0 10.1 5.3 6.6 10.1 14.6 14.5 7.1 14.5 8.9 9.5 17.6 6.5 13.2 16.8 7.3 11.4 18.4 5.6 7.4 4.8 6.4 29.0 11.6 11.1 8.6 8.1 4.9 14.9 6.3 15.0 12.9 3.3 11.8 25.5 12.6 10.1 3.3 23.4 17.5 12.5 34.5 8.0 5.8 17.2 12.3 4.6 18.7 21.1 35.1 22.8 18.5 15.7 22.1 13.9 19.1 22.4 65.5 165.7 52.5 97.7 146.0 66.2 34.7 25.5 105.7 153.6 43.6 86.4 24.4 3.3 30.1 45.6 46.5 39.7 23.3 32.9 20.4 79.4 107.2 94.9 29.8 22.2 54.0 56.9 23.4 43.8 28.3 32.2 70.9 91.1 47.7 34.3 34.1 46.6 37.7 35.3 8.7 80.7 32.3 55.9 14.4 10.0 158.0 50.6 94.7 35.1 111.1 CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884806-7912760 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Approved "Nucleoplasm,Nucleoli,Centriolar satellite" No No "Nucleoplasm, Nucleoli, Centriolar satellite" "HPA043368: AB_2678448, HPA076524: AB_2686804" "unprognostic (1.77e-2)" "unprognostic (8.01e-2)" "prognostic unfavorable (2.43e-4)" "prognostic favorable (7.68e-5)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.83e-2)" "unprognostic (5.25e-3)" "prognostic favorable (8.36e-4)" "unprognostic (9.11e-2)" "unprognostic (8.31e-2)" "unprognostic (3.98e-2)" "unprognostic (1.50e-1)" "unprognostic (8.90e-3)" "unprognostic (2.20e-3)" 10.4 12.9 31.7 24.3 26.0 18.7 12.5 12.1 28.3 41.1 21.1 4.1 22.5 8.2 46.3 16.1 15.1 25.0 20.0 8.7 30.4 14.2 15.2 2.3 13.1 19.0 8.4 28.4 27.3 15.1 28.5 21.0 8.0 10.7 32.9 11.1 20.7 19.4 23.0 3.3 16.2 14.0 23.3 6.9 14.6 15.8 11.3 5.1 40.6 19.7 7.5 17.7 20.6 28.9 1.6 4.0 4.1 3.5 2.7 7.8 3.6 12.2 30.5 17.9 23.7 21.8 18.3 9.6 14.3 19.2 12.1 13.0 5.9 10.3 34.5 10.9 21.0 9.8 16.6 33.6 15.1 15.3 17.5 19.6 16.7 39.6 0.7 11.7 4.8 32.9 24.1 8.1 16.3 10.9 32.3 22.5 15.8 11.1 0.6 11.3 12.1 13.1 5.5 2.8 12.9 11.3 38.6 21.8 5.2 12.1 29.8 12.2 16.5 35.5 13.8 6.9 5.1 15.9 7.8 28.1 26.3 20.7 6.4 20.5 2.6 0.4 19.5 13.4 13.5 22.4 0.6 2.7 4.1 7.0 1.7 5.5 1.5 6.7 6.6 2.1 1.6 7.8 5.1 2.1 2.7 3.5 4.0 3.6 3.6 31.7 26.0 12.1 28.3 30.4 14.2 8.4 28.4 10.7 5.1 29.8 57.4 11.5 44.3 32.4 61.2 9.7 17.8 24.1 37.5 76.8 7.9 15.1 14.9 21.3 8.9 17.5 12.0 0.0 20.6 16.7 30.0 67.6 38.2 2.1 8.4 42.9 54.5 18.4 21.1 13.0 41.1 14.7 8.5 54.1 12.6 11.3 23.7 7.0 53.7 7.5 15.6 25.8 27.2 12.9 50.5 17.9 13.7 34.6 25.9 53.1 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm NA NA Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 23.5 34.9 21.9 50.0 33.5 27.2 25.9 29.4 25.1 28.1 29.5 29.3 38.5 18.6 37.2 35.4 29.1 28.0 40.3 52.8 23.5 19.2 29.5 25.0 25.5 30.9 33.6 19.4 34.6 27.4 58.4 25.3 29.5 27.2 21.5 26.0 26.5 24.8 46.2 33.7 31.1 24.4 36.6 30.3 29.4 27.2 29.7 28.9 75.7 38.4 33.7 38.4 34.7 24.3 12.6 16.8 12.8 9.1 13.5 16.7 5.8 20.4 18.7 46.4 17.4 19.0 21.4 27.3 22.7 22.2 25.1 23.2 31.2 15.9 44.1 9.0 25.7 16.4 18.3 43.5 25.0 33.9 33.0 22.4 61.6 29.1 19.4 16.5 48.3 29.6 20.7 12.4 24.3 17.0 31.7 29.3 24.7 48.4 22.0 23.8 25.6 45.8 15.8 44.4 19.0 17.7 39.3 28.5 24.1 15.9 24.2 22.0 28.3 29.2 32.6 22.6 53.2 14.9 27.5 27.2 25.7 54.7 18.8 26.5 35.7 21.2 56.3 17.0 29.5 18.7 9.0 7.7 9.2 12.2 9.1 12.0 10.5 10.3 11.1 7.9 12.6 13.0 12.3 12.8 13.5 8.1 16.8 16.7 5.8 21.9 33.5 29.4 25.1 23.5 19.2 33.6 19.4 27.2 28.9 56.6 102.0 59.1 45.6 60.9 103.2 110.8 66.2 96.4 79.6 83.7 66.8 38.6 11.6 71.4 71.8 70.5 43.4 23.3 62.1 41.7 66.9 40.2 81.1 60.6 61.2 131.9 93.2 49.7 44.2 45.3 60.9 57.6 45.5 56.9 59.2 71.6 76.6 24.6 70.0 30.3 60.2 51.8 73.5 97.0 107.1 59.1 56.9 61.8 61.8 37.3 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101793-6180123 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.4;pituitary gland: 22.3;testis: 16.4" "Cell type enhanced" "Detected in some" 17 "Bipolar cells: 60.3;Early spermatids: 202.3;Horizontal cells: 212.9;Late spermatids: 67.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 17.0;U-2 OS: 7.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 1.1 7.9 19.8 1.3 17.1 1.0 1.0 12.1 41.4 1.2 1.4 0.7 0.0 1.3 1.2 1.2 1.5 1.2 1.2 1.6 15.3 10.1 1.3 1.0 1.2 1.0 4.3 19.1 1.1 1.4 1.3 22.3 1.0 8.0 1.9 1.3 2.3 1.2 4.8 1.2 1.0 1.4 1.2 1.6 1.1 1.2 16.4 0.8 0.0 1.0 0.0 1.0 1.1 0.4 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.2 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 1.5 0.0 0.1 0.3 1.3 0.0 0.0 0.0 0.0 17.0 0.2 0.2 0.0 0.0 0.0 2.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 19.8 17.1 12.1 34.2 15.3 10.1 4.3 19.1 8.0 0.8 0.0 0.0 0.0 0.0 0.1 60.3 1.7 0.0 0.0 0.0 3.5 11.8 0.0 0.0 0.0 202.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 212.9 0.0 0.0 0.0 67.4 0.9 0.0 0.0 0.0 0.0 2.0 0.4 0.0 0.4 0.0 48.3 0.0 0.9 3.4 17.0 0.4 0.0 0.0 0.0 0.0 CHD6 "CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB" ENSG00000124177 "Chromodomain helicase DNA binding protein 6" Q8TD26 20 41402101-41618494 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 143.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015543 Approved Nucleoplasm NA NA Nucleoplasm "HPA015543: " "unprognostic (5.13e-3)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "unprognostic (1.36e-1)" "unprognostic (4.72e-3)" "prognostic favorable (3.42e-4)" "unprognostic (1.17e-1)" "unprognostic (3.17e-1)" "unprognostic (4.75e-2)" "unprognostic (1.14e-1)" "unprognostic (2.12e-3)" "unprognostic (6.66e-2)" "unprognostic (3.41e-1)" "unprognostic (1.00e-1)" "unprognostic (1.14e-2)" 12.1 12.6 16.5 12.7 16.2 18.1 19.4 34.1 24.9 17.4 11.3 16.6 15.4 6.5 20.4 19.9 11.0 16.3 11.7 12.1 15.8 13.9 11.8 10.7 11.7 12.1 14.7 16.8 26.1 12.5 31.4 30.3 12.9 24.3 19.7 10.0 14.2 14.5 17.0 9.4 14.4 10.5 14.4 17.3 12.0 12.3 11.1 18.2 21.4 21.4 6.7 15.3 16.9 15.0 12.0 11.5 15.1 9.3 10.4 10.4 2.3 6.4 7.6 16.5 7.2 9.4 9.7 11.0 5.7 11.7 10.1 12.4 10.5 5.3 7.7 10.3 9.6 11.4 9.6 10.3 9.7 11.6 2.4 5.0 10.6 7.0 10.1 5.3 8.2 5.3 9.7 9.1 7.3 8.2 10.8 8.7 10.9 8.3 8.8 7.8 17.7 13.0 9.0 5.4 4.0 12.9 10.1 19.6 5.5 6.3 15.0 14.9 10.3 17.2 4.6 11.5 12.6 7.9 6.2 9.9 16.0 7.9 8.5 4.9 8.0 6.4 10.0 7.1 4.0 5.0 15.1 6.5 7.1 8.9 6.2 8.9 8.8 7.7 7.3 5.1 12.0 10.4 8.7 0.9 10.4 9.3 11.5 5.9 2.3 16.5 16.2 34.1 24.9 15.8 13.9 14.7 16.8 24.3 18.2 44.7 25.0 32.1 38.2 16.1 123.2 51.6 22.9 45.5 34.2 21.0 88.4 26.6 18.3 19.0 12.5 32.3 4.8 0.0 13.7 22.1 28.6 28.3 20.8 18.7 14.3 143.0 58.3 23.9 21.3 14.0 46.1 23.5 16.9 32.5 27.7 76.4 14.4 14.0 42.8 10.6 137.4 19.4 29.7 22.1 59.7 15.1 27.3 31.9 20.9 22.3 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678778-60868028 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.1" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 227.8;Muller glia cells: 155.9;Rod photoreceptor cells: 196.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 12.2;granulocytes: 12.6;T-cells: 5.5" "Cell line enhanced" "Detected in many" "AF22: 26.3;SCLC-21H: 24.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 110.3" HPA053075 Supported Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA053075: AB_2682035" "unprognostic (3.77e-2)" "unprognostic (3.28e-3)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.34e-5)" "unprognostic (9.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-3)" "unprognostic (3.41e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (9.09e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (2.17e-1)" 3.9 2.2 7.0 7.9 11.2 25.1 4.1 47.1 9.0 2.3 5.7 13.4 3.1 5.9 2.6 3.2 5.1 3.2 3.1 4.1 8.1 4.3 3.6 3.6 4.7 7.0 8.1 3.3 1.4 6.4 12.4 9.9 5.6 9.9 2.9 5.5 6.4 5.7 2.8 10.3 5.7 6.6 2.4 7.5 6.1 4.5 4.3 12.2 1.6 5.4 2.2 7.3 2.9 5.9 12.2 0.6 12.6 0.6 0.0 5.5 0.4 3.9 2.0 26.3 4.6 0.1 0.0 8.3 0.2 0.0 0.9 0.8 4.9 3.7 7.6 0.5 0.0 1.2 2.4 13.5 3.9 0.8 2.9 7.2 17.9 3.3 6.4 1.1 5.4 3.3 0.5 3.0 0.0 4.4 1.6 3.9 6.2 1.3 6.8 0.6 4.0 8.4 6.2 18.0 3.9 0.9 17.6 6.2 2.4 2.0 4.5 24.0 11.9 0.7 3.0 7.3 9.7 5.3 5.1 4.5 0.3 4.3 0.3 2.1 7.3 4.2 11.9 1.5 0.6 6.7 10.4 0.3 12.6 2.6 0.1 3.3 8.0 2.9 0.9 0.1 12.2 5.5 2.0 7.1 0.0 0.6 0.6 0.2 0.4 7.0 11.2 47.1 6.5 8.1 4.3 8.1 3.3 9.9 12.2 29.8 17.4 46.9 22.3 27.0 32.3 30.7 30.6 20.1 23.9 15.7 227.8 7.1 1.7 15.6 11.9 29.6 17.6 0.0 9.7 5.5 7.1 31.3 38.3 9.5 11.9 66.7 83.8 27.0 12.9 7.6 0.9 10.3 20.3 19.8 30.6 155.9 13.9 22.6 0.4 4.2 196.3 0.0 4.4 4.9 3.4 28.2 5.1 13.8 21.7 25.1 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced Nucleoplasm NA NA Nucleoplasm "HPA052186: AB_2681754, HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favorable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 13.9 14.5 13.0 14.8 21.5 34.8 17.0 28.9 25.7 15.8 14.4 26.6 14.1 11.1 18.3 13.4 17.4 15.9 11.7 12.3 13.5 13.3 14.0 11.2 15.5 18.5 15.4 15.2 20.7 19.0 34.7 25.3 15.2 20.3 16.3 14.6 19.3 15.7 14.9 16.9 24.5 16.4 17.2 13.1 19.2 16.1 15.2 18.1 29.9 17.4 10.4 24.8 16.6 14.5 12.3 7.8 12.8 7.4 8.7 8.6 3.0 16.5 21.7 24.1 11.2 15.4 13.3 13.6 13.2 15.2 20.1 20.1 18.8 14.4 27.4 8.3 17.6 15.9 20.3 29.4 18.5 25.4 20.9 13.4 24.0 14.5 22.8 14.3 33.2 22.9 17.9 15.1 22.5 16.2 15.6 17.8 21.7 16.7 14.7 15.1 17.8 23.8 13.6 18.4 16.1 18.4 22.4 18.2 9.2 14.9 30.6 17.6 16.9 20.6 16.1 11.4 22.7 11.3 16.1 20.9 16.7 12.8 9.8 15.6 16.7 19.9 27.4 6.7 12.3 16.6 12.8 4.8 12.1 7.7 5.0 8.6 5.8 6.8 7.5 3.3 12.3 7.4 6.4 11.0 8.7 7.4 7.8 5.7 3.0 13.0 21.5 28.9 25.7 13.5 13.3 15.4 15.2 20.3 18.1 35.7 52.5 15.1 10.4 11.2 32.4 18.1 20.4 36.1 43.3 31.4 25.5 12.2 1.7 19.0 1.6 18.0 11.3 23.3 20.2 10.1 9.9 12.1 26.7 12.4 15.0 22.3 26.0 14.1 20.9 2.5 15.0 13.0 10.1 19.8 16.3 19.2 21.3 14.0 16.6 6.3 22.9 0.0 13.3 26.2 22.4 14.4 10.3 22.3 14.7 11.1 CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53055033-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 8 "Cone photoreceptor cells: 473.2;Rod photoreceptor cells: 752.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 42.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042053, HPA049420, HPA066155" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA042053: AB_2677823, HPA049420: AB_2680758, HPA066155: " "unprognostic (3.57e-2)" "unprognostic (3.73e-2)" "unprognostic (3.44e-3)" "unprognostic (2.42e-1)" "unprognostic (4.34e-2)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "unprognostic (7.75e-3)" "unprognostic (2.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (5.09e-2)" "unprognostic (2.87e-1)" 18.0 12.6 14.5 12.5 17.3 30.3 15.7 49.3 19.6 18.5 13.8 6.6 17.4 8.0 14.2 15.0 14.4 13.5 11.6 12.2 15.9 8.2 16.8 12.3 12.3 9.2 16.0 12.3 18.8 12.9 28.1 39.9 12.3 15.1 13.7 11.5 8.9 17.8 15.3 17.1 14.4 11.1 11.6 20.1 11.6 13.4 7.0 18.7 15.6 17.7 11.2 9.4 13.9 15.1 16.4 42.9 23.7 12.7 12.1 8.8 1.7 5.8 6.8 15.2 12.3 11.3 16.6 2.6 10.7 7.9 5.7 2.5 3.7 5.2 7.8 7.0 8.8 3.9 7.1 7.9 5.6 8.0 2.7 5.9 11.0 6.5 2.4 7.9 15.2 9.2 11.5 5.6 8.3 10.5 7.6 8.4 4.4 12.9 2.6 7.1 2.3 7.6 3.5 5.5 1.7 5.2 26.8 18.2 3.3 3.4 5.5 6.4 7.2 9.5 3.1 7.9 5.7 3.4 7.0 16.2 10.7 5.4 3.9 7.1 8.1 5.6 13.6 7.6 6.6 10.5 23.7 9.2 8.9 5.7 7.6 8.8 12.5 3.9 6.2 5.4 16.4 3.1 4.4 3.0 12.1 12.7 42.9 1.9 1.7 14.5 17.3 49.3 19.6 15.9 8.2 16.0 12.3 15.1 18.7 65.5 56.6 64.3 103.8 50.8 251.0 33.9 43.3 68.3 67.1 85.5 473.2 14.5 39.7 49.7 11.6 77.2 66.9 46.7 32.4 24.2 77.4 86.0 91.5 61.4 61.8 208.2 84.2 88.4 58.8 14.5 100.4 67.6 64.1 74.9 67.1 159.3 29.5 60.4 116.0 47.5 752.2 58.2 73.1 79.9 36.0 65.6 20.8 48.9 69.8 73.2 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase, acidic" Q9BZP6 1 111290862-111320566 "Enzymes, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 66.6" "Cell type enriched" "Detected in some" 8 "Alveolar cells type 2: 22.2" "Cancer enhanced" "Detected in some" "lung cancer: 1.8;stomach cancer: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "ASC diff: 6.0;HAP1: 3.1" "Low region specificity" "Detected in single" HPA059193 Approved "Intracellular and membrane" NA NA "HPA059193: AB_2683942" "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.7 0.5 0.8 0.3 0.1 0.1 0.1 0.0 0.5 1.0 13.2 0.2 0.1 0.1 0.1 0.1 0.6 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 66.6 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 1.6 0.7 0.0 0.1 0.6 0.6 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.0 0.2 0.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.7 0.2 0.2 0.0 1.6 0.6 0.0 0.0 0.6 0.0 0.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 22.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 99.9;lymphoid tissue: 106.5" "Cell type enriched" "Detected in single" 44 "Hofbauer cells: 42.8" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 2.9;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 4 "granulocytes: 2.9;monocytes: 1.1" "Cell line enhanced" "Detected in some" "EFO-21: 2.8;LHCN-M2: 1.7;RH-30: 1.8;U-266/70: 2.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" NA NA 26400000 58000000 "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favorable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 99.9 0.2 0.2 0.4 0.3 26.7 5.5 0.1 0.3 5.9 0.6 0.5 0.1 0.0 2.5 0.2 0.3 0.1 0.2 0.6 0.2 0.1 0.1 0.4 22.1 106.5 0.4 0.1 1.4 1.1 0.0 0.2 0.4 0.5 0.6 0.5 0.3 0.3 0.1 0.1 0.3 0.7 0.2 9.4 4.3 0.1 0.1 0.1 2.3 0.9 0.2 0.5 0.1 0.3 0.5 0.2 2.9 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 1.7 0.2 0.0 0.0 0.1 0.0 0.2 0.0 1.8 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 2.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.9 0.0 1.1 0.2 0.0 1.3 0.2 0.3 0.1 0.3 0.2 0.1 0.4 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 42.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CLPB "ANKCLB, FLJ13152, HSP78, SKD3" ENSG00000162129 "ClpB homolog, mitochondrial AAA ATPase chaperonin" Q9H078 11 72285495-72434680 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 87.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4145.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 18.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039005, HPA039006, HPA064571" Enhanced NA NA "HPA039005: AB_2676305, HPA039006: AB_10672767, HPA064571: AB_2685290" "unprognostic (9.36e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.23e-1)" "unprognostic (2.99e-1)" "unprognostic (2.05e-2)" "unprognostic (8.22e-2)" "unprognostic (8.37e-2)" "unprognostic (2.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "prognostic favorable (8.36e-8)" "unprognostic (9.29e-2)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (3.28e-2)" 4.4 6.1 5.7 4.8 7.2 7.9 3.4 5.6 10.5 3.1 3.1 6.7 2.5 3.2 3.8 3.1 3.7 2.9 2.9 4.1 4.9 4.1 6.7 8.5 3.7 3.0 5.7 5.9 3.2 5.5 8.6 3.4 6.5 7.9 2.7 3.1 3.1 4.2 3.3 6.5 2.8 2.9 4.5 3.9 3.9 3.7 87.9 6.4 2.7 4.7 1.8 2.9 3.7 3.0 1.6 18.3 4.0 11.7 1.8 2.4 5.2 6.4 18.3 5.7 11.8 7.8 5.8 14.8 6.9 4.2 10.4 7.8 24.4 9.7 16.5 16.0 6.5 18.2 13.7 15.3 15.1 12.8 14.9 11.5 13.9 19.0 14.5 6.7 14.0 24.8 7.6 5.0 18.4 18.6 4.1 11.6 14.6 18.9 11.7 7.4 16.9 12.5 13.3 6.0 21.9 18.3 11.4 8.6 7.1 6.0 11.0 14.4 11.0 9.4 21.7 16.1 7.9 11.2 12.1 9.1 14.8 9.6 15.0 13.3 5.6 8.0 9.4 7.9 11.9 11.3 4.0 11.7 0.6 2.4 9.3 2.4 1.5 1.4 2.1 18.3 1.6 1.8 1.4 1.0 1.8 5.2 3.3 0.8 5.2 5.7 7.2 5.6 10.5 4.9 4.1 5.7 5.9 7.9 6.4 14.9 8.9 9.0 3.7 0.3 2.5 3.1 5.1 6.7 9.1 8.7 3.9 12.5 5.0 12.7 991.0 7.2 4.0 0.0 14.2 13.7 3.1 2.7 3.5 9.7 19.2 3.2 0.0 1.3 10.6 4145.4 23.3 12.7 1.7 7.2 1.0 1.3 10.6 0.8 17.3 17.4 5.7 12.9 2.1 35.9 21.3 1.0 27.7 2.5 1.9 5.1 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361452-6368910 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria NA NA Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 22.1 27.3 18.4 22.5 18.8 20.1 19.9 16.6 20.9 16.1 23.2 17.9 22.2 25.4 16.9 15.1 26.6 15.3 19.2 28.9 17.4 16.7 28.5 64.7 15.5 35.5 19.0 15.2 23.7 32.7 11.6 18.5 18.4 13.6 19.1 14.1 18.6 26.3 23.4 73.1 17.8 26.0 14.8 16.7 21.2 21.3 21.1 11.4 54.8 27.0 25.1 25.3 20.7 23.2 29.7 37.5 14.9 20.0 27.6 46.3 32.9 31.6 21.1 15.4 28.1 9.7 13.5 16.0 18.8 13.8 26.8 24.1 16.9 11.6 31.9 29.3 15.0 15.3 19.8 15.3 23.7 10.2 33.1 47.9 23.5 18.6 25.0 26.3 21.2 31.1 17.1 17.4 18.6 20.8 18.4 26.0 42.3 23.3 43.3 17.5 37.0 36.3 22.2 22.2 24.5 49.5 25.6 18.6 48.4 19.9 17.7 25.5 24.5 11.9 29.2 27.6 10.0 15.0 30.4 18.2 17.8 16.5 41.6 35.4 55.6 46.4 30.7 24.3 30.0 28.2 5.5 20.0 10.5 28.0 17.7 33.2 28.3 39.9 34.5 24.1 29.7 35.2 34.1 14.9 27.6 12.1 37.5 46.3 32.9 18.4 18.8 16.6 20.9 17.4 16.7 19.0 15.2 13.6 11.4 20.8 35.7 37.2 49.7 40.0 30.7 40.3 58.6 36.1 17.0 41.8 11.8 60.5 122.7 78.4 82.6 46.3 64.7 23.3 84.4 102.0 37.0 67.2 25.4 81.5 71.6 20.6 33.9 49.1 31.4 188.9 39.4 35.5 52.3 93.8 43.9 34.4 88.0 56.1 40.7 126.3 20.5 12.9 36.0 68.8 45.8 32.4 48.3 53.2 60.6 56.1 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 15 "granulocytes: 52.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "T-reg: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Cell line enhanced" "Detected in some" "HL-60: 1.7;SuSa: 2.5;U-937: 3.1" "Low region specificity" "Detected in single" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 3000000 "Cytoplasmic bodies" Cytosol "CAB000363: AB_2083616, HPA052634: AB_2681892" "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 12.3 0.2 0.2 2.9 0.2 0.0 15.9 0.2 0.2 7.3 6.2 0.2 1.2 0.1 2.9 6.0 8.3 1.0 10.0 10.3 0.2 0.2 2.0 0.8 1.1 1.6 0.2 0.2 0.6 0.9 0.5 0.5 0.7 0.3 6.0 6.9 3.0 5.9 1.3 1.2 13.0 5.3 6.2 0.2 0.5 2.4 2.7 0.2 1.0 0.4 7.9 3.9 4.1 2.0 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 1.5 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.7 0.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.9 1.0 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.8 2.5 0.0 0.8 1.4 0.0 0.2 0.3 0.3 0.8 0.9 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534440-74587212 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 60.3;liver: 41.4" "Cell type enhanced" "Detected in some" 24 "Early spermatids: 6.1;Hepatocytes: 26.1;Proximal tubular cells: 14.6" "Group enriched" "Detected in some" 10 "glioma: 4.4;liver cancer: 1.0;melanoma: 1.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in single" 69 "U-266/84: 42.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA008933, HPA073283" Enhanced "Secreted in brain" NA NA 1900000000 "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 1.1 1.2 14.9 1.2 28.2 1.3 1.1 4.5 60.3 1.1 1.1 54.9 0.0 5.7 1.1 2.1 1.1 1.1 1.3 1.1 28.9 15.1 1.9 41.4 1.1 1.2 44.1 12.9 1.1 1.2 1.1 0.1 1.1 50.0 1.2 1.1 0.5 1.1 1.3 2.2 1.1 1.9 1.1 51.1 1.1 1.2 1.4 28.8 0.0 1.3 0.0 1.1 1.1 0.0 0.7 0.7 1.9 0.5 1.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 42.2 0.0 0.0 0.0 0.0 1.3 0.5 0.4 0.4 0.2 0.2 0.3 0.3 0.2 0.1 0.7 0.4 0.4 1.9 1.0 0.2 0.7 0.2 0.2 14.9 28.2 4.5 22.5 28.9 15.1 44.1 12.9 50.0 28.8 0.0 0.0 0.0 0.2 0.1 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 6.1 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 26.1 0.1 0.0 0.0 0.6 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 14.6 0.6 0.0 0.0 0.9 0.5 0.3 0.0 0.5 0.0 0.2 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 76.6;RPMI-8226: 98.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2400000 "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 19.0 11.5 31.0 19.1 36.0 6.1 16.9 10.4 33.0 39.4 37.6 45.2 27.0 51.3 12.5 35.3 20.4 38.9 25.9 11.6 31.1 26.4 89.0 66.4 22.1 23.0 36.1 24.1 11.4 27.6 15.7 13.7 28.8 27.2 34.7 22.2 14.1 16.9 32.7 7.5 11.8 71.1 10.4 39.4 39.2 27.2 6.5 32.5 10.9 43.9 11.6 21.4 28.4 12.0 29.6 49.0 12.5 44.4 31.4 23.9 30.3 10.2 13.9 10.1 9.5 12.3 7.3 42.4 10.8 10.2 14.8 14.8 8.0 11.1 13.0 13.7 11.7 11.6 15.6 15.3 20.5 10.6 19.4 6.0 12.9 7.0 12.8 18.0 25.2 20.1 11.0 15.8 12.8 23.1 8.4 12.9 15.6 13.6 76.6 9.8 11.5 13.4 12.1 15.2 6.8 8.3 14.6 11.6 98.6 58.2 43.1 11.0 5.8 8.4 60.2 14.4 25.2 25.2 10.4 13.5 15.9 13.5 3.5 7.2 14.3 58.7 17.3 10.8 18.4 13.2 7.8 30.0 12.5 21.8 44.4 23.8 28.9 17.6 20.3 49.0 29.6 19.1 20.7 4.4 31.4 43.1 43.0 23.9 30.3 31.0 36.0 10.4 33.0 31.1 26.4 36.1 24.1 27.2 32.5 68.5 54.2 53.8 35.3 8.1 33.7 22.9 91.7 60.2 38.7 113.4 15.7 128.9 159.2 142.6 2.2 45.9 105.2 0.0 136.1 106.3 20.6 56.1 11.5 102.8 184.6 41.3 62.7 36.8 86.2 3.2 17.3 82.3 16.9 112.8 71.7 80.3 99.7 74.1 15.6 371.2 24.6 12.9 15.9 4.8 7.3 8.4 91.2 36.3 82.5 47.4 CNOT6 "CCR4, Ccr4a, KIAA1194" ENSG00000113300 "CCR4-NOT transcription complex subunit 6" Q9ULM6 5 180494412-180578405 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044568 Approved Approved Cytosol NA NA Cytosol "HPA044568: AB_10797257" "unprognostic (9.41e-3)" "unprognostic (1.40e-1)" "unprognostic (2.03e-3)" "unprognostic (2.55e-1)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (4.03e-2)" "unprognostic (3.57e-2)" 10.2 10.1 19.2 15.4 20.2 14.4 13.3 43.9 18.7 12.0 16.4 11.7 9.7 16.2 13.1 12.4 19.6 13.3 12.7 13.0 15.9 11.1 14.1 8.6 13.0 14.3 12.3 14.0 14.8 10.3 13.4 12.7 17.6 12.9 13.9 16.2 14.3 13.4 10.9 8.3 14.4 20.6 13.4 12.3 17.0 13.7 17.6 14.9 25.1 12.6 10.0 18.4 16.9 24.5 2.2 2.5 3.4 5.8 2.1 4.5 1.7 11.1 13.4 27.6 22.0 4.6 5.3 28.5 8.1 5.5 10.9 13.0 16.3 16.4 11.8 12.5 5.3 15.1 11.7 23.0 27.2 12.8 34.5 11.5 12.8 18.1 10.5 6.8 14.9 9.4 4.4 13.2 8.0 17.0 10.2 13.2 13.9 13.6 11.4 10.0 22.9 18.9 9.0 8.1 11.2 6.4 17.5 13.9 8.4 12.0 22.1 20.2 17.1 13.8 18.5 11.8 14.1 23.1 15.1 14.3 11.6 13.4 8.4 14.4 7.4 13.3 12.5 11.0 20.5 9.5 1.5 2.6 3.4 3.8 4.1 4.0 2.0 3.3 2.3 2.4 2.2 4.5 4.4 2.2 2.1 5.8 2.5 2.3 1.7 19.2 20.2 43.9 18.7 15.9 11.1 12.3 14.0 12.9 14.9 26.8 12.0 6.7 5.5 19.3 18.0 9.6 10.2 8.1 6.8 10.4 21.6 7.9 1.7 10.2 5.2 11.9 11.1 0.0 7.8 9.9 10.4 14.0 2.3 5.7 10.6 17.5 13.9 14.7 16.7 7.5 12.0 13.1 10.1 8.2 14.3 13.1 12.9 5.8 17.7 11.8 15.3 25.8 7.3 39.4 56.2 19.4 9.6 12.9 15.1 12.9 CNOT6L "Ccr4b, DKFZp434K098" ENSG00000138767 "CCR4-NOT transcription complex subunit 6 like" Q96LI5 4 77713387-77819615 "Enzymes, Predicted intracellular proteins" "mRNA processing, RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 51.3" "Cell type enhanced" "Detected in many" 5 "T-cells: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042688 Uncertain Supported Cytosol NA NA Cytosol "HPA042688: AB_10794384" "unprognostic (3.91e-1)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.10e-2)" "unprognostic (2.56e-1)" "unprognostic (3.72e-2)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (5.06e-2)" "unprognostic (6.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.51e-2)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-3)" 13.6 7.8 8.6 21.5 8.2 15.3 11.0 11.1 9.2 7.8 7.3 7.0 4.6 7.5 11.4 6.3 10.2 7.1 8.3 7.5 6.0 5.7 7.7 10.8 12.7 19.2 7.6 7.3 8.8 10.8 14.6 10.0 12.3 6.7 8.4 8.9 10.3 9.9 7.4 9.1 12.2 11.5 8.4 6.9 23.4 7.9 7.3 5.6 51.3 9.1 6.2 21.1 10.7 10.3 7.5 6.1 20.2 9.3 7.4 10.0 4.4 8.8 5.7 7.2 4.8 8.5 7.4 7.1 7.0 9.3 6.3 8.6 2.2 9.9 15.3 8.9 9.8 5.0 5.7 9.3 9.7 8.5 15.3 5.2 14.3 7.9 6.4 5.4 14.2 12.6 4.8 12.6 7.1 13.0 6.0 20.0 11.1 11.9 20.5 7.3 6.0 26.2 7.2 3.3 7.0 1.8 6.5 20.4 10.9 7.2 10.0 8.9 4.3 12.1 11.1 4.9 8.8 3.5 7.3 21.7 6.1 6.8 11.5 3.8 26.3 11.2 19.0 6.6 6.2 4.5 20.2 4.7 10.2 10.0 7.0 10.0 5.3 7.5 7.8 4.5 7.5 7.3 8.5 6.7 7.4 9.3 6.1 6.0 4.4 8.6 8.2 11.1 9.2 6.0 5.7 7.6 7.3 6.7 5.6 20.8 16.0 29.6 11.9 51.4 38.1 14.5 22.9 14.7 28.4 34.9 37.3 22.8 51.4 5.9 3.4 42.7 16.9 0.0 10.5 7.4 21.1 30.3 36.9 27.0 14.9 30.2 25.2 41.7 40.3 2.8 17.3 33.5 23.6 14.4 31.3 20.1 8.9 14.0 12.0 17.0 40.7 32.3 31.7 19.1 30.9 57.7 20.4 121.5 23.0 16.3 CNOT7 CAF1 ENSG00000198791 "CCR4-NOT transcription complex subunit 7" Q9UIV1 8 17224964-17246878 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069543 Supported "Nuclear bodies" NA NA "Nuclear bodies" "HPA069543: AB_2686148" "unprognostic (1.55e-1)" "unprognostic (4.49e-2)" "prognostic favorable (4.99e-4)" "unprognostic (4.61e-2)" "unprognostic (8.45e-2)" "unprognostic (3.10e-2)" "unprognostic (1.44e-3)" "unprognostic (4.54e-2)" "unprognostic (6.83e-2)" "unprognostic (4.09e-3)" "unprognostic (2.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-2)" "unprognostic (1.72e-1)" "unprognostic (4.51e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" 18.3 25.8 28.7 23.8 37.0 24.2 23.3 34.6 31.8 17.5 22.8 15.9 19.8 20.8 22.2 26.1 24.5 20.6 19.8 21.4 22.3 29.3 28.2 36.8 17.9 32.0 22.3 22.5 25.9 28.0 40.4 29.7 25.0 23.1 19.3 24.6 18.2 32.3 22.4 43.2 18.5 22.7 20.6 19.8 27.6 19.0 26.9 22.4 60.6 33.6 19.6 34.3 25.5 19.4 57.8 49.9 46.6 50.7 45.2 67.0 52.2 20.6 25.6 38.5 28.6 16.3 17.2 26.6 26.7 22.8 30.9 27.5 29.9 16.6 28.6 29.4 23.3 49.8 16.6 40.5 33.6 45.3 11.8 19.4 37.5 19.7 32.1 20.9 25.2 23.2 16.3 27.9 26.3 28.3 28.7 36.8 37.9 31.3 31.8 31.1 16.1 61.8 23.5 42.5 38.9 19.6 33.7 28.7 21.4 26.9 45.5 48.7 32.6 18.8 16.7 30.3 33.2 20.1 21.4 24.6 23.2 32.9 25.8 29.8 16.6 52.7 50.0 21.7 24.0 22.8 46.3 43.3 46.6 38.1 50.7 45.3 57.8 52.9 45.2 49.9 57.1 67.0 52.7 37.9 45.2 43.5 44.9 57.5 52.2 28.7 37.0 34.6 31.8 22.3 29.3 22.3 22.5 23.1 22.4 29.8 32.3 80.8 57.6 80.7 97.7 49.1 53.5 56.2 22.7 59.3 88.4 76.2 82.9 70.4 44.6 51.8 30.7 0.0 63.0 95.5 40.9 72.1 42.8 61.4 61.1 23.8 90.3 67.5 70.8 26.1 37.7 46.6 25.3 52.3 67.6 50.4 66.7 77.0 38.2 86.0 166.3 77.6 44.5 77.2 96.3 75.2 71.5 61.0 73.1 64.8 CNOT8 "CAF1, CALIF, hCAF1, POP2" ENSG00000155508 "CCR4-NOT transcription complex subunit 8" Q9UFF9 5 154857553-154876793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051398 Approved NA NA "HPA051398: AB_2681468" "unprognostic (2.51e-1)" "unprognostic (4.26e-1)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.19e-1)" "unprognostic (3.62e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (2.80e-1)" "unprognostic (3.32e-3)" "unprognostic (2.19e-1)" "unprognostic (1.84e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.41e-4)" 40.5 28.0 23.6 20.9 23.8 60.1 30.3 20.3 29.2 26.0 23.5 21.3 19.5 19.0 21.1 22.5 18.2 18.2 17.5 17.2 23.2 16.1 17.1 16.6 33.5 30.5 33.0 18.3 20.0 16.2 20.1 17.8 23.9 24.4 17.4 27.5 16.5 24.1 17.5 14.3 28.0 23.7 23.2 25.9 30.7 19.1 24.4 26.2 41.5 36.0 11.3 29.5 24.6 22.8 20.5 33.4 65.4 31.9 20.9 31.5 36.6 12.1 14.1 24.5 26.9 23.4 21.4 18.6 18.8 20.9 20.7 32.2 17.9 27.2 21.4 23.7 16.1 16.6 13.4 16.8 23.3 23.6 10.6 17.4 17.9 21.8 15.9 14.9 41.1 33.3 14.5 20.5 18.4 16.0 21.6 25.4 30.8 15.8 16.2 21.6 14.6 36.3 43.0 13.2 14.2 8.3 30.5 20.7 22.2 16.4 16.9 19.2 28.6 25.2 20.3 23.3 14.3 19.0 33.8 19.7 22.0 13.8 12.0 12.3 15.7 20.1 32.9 15.5 32.8 13.7 55.0 31.9 65.4 19.3 22.6 21.4 20.5 24.0 23.1 33.4 20.4 31.5 22.7 32.2 20.9 17.7 18.0 26.0 36.6 23.6 23.8 20.3 29.2 23.2 16.1 33.0 18.3 24.4 26.2 17.9 32.0 20.1 13.9 28.3 12.5 11.0 7.6 8.1 20.5 15.7 0.0 28.2 14.9 20.2 92.9 31.9 15.8 0.0 17.6 33.4 37.2 20.2 17.3 11.9 24.3 17.5 26.5 27.6 48.1 44.7 42.0 26.9 27.0 40.5 33.2 11.3 24.2 14.0 35.7 9.9 7.4 6.5 19.3 30.2 21.5 36.5 19.1 38.3 25.5 21.4 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966741-41977731 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 211.7" "Cell type enhanced" "Detected in many" 4 "Distal tubular cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 49.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Supported "Plasma membrane" NA NA 730000 "Plasma membrane" "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 9.1 8.9 51.4 9.5 72.8 6.7 8.1 13.4 125.3 10.3 7.5 211.7 2.3 7.1 8.0 12.7 15.0 9.3 10.8 7.6 78.4 40.7 14.7 9.6 6.7 10.5 86.7 49.0 11.2 9.2 5.8 4.4 7.8 66.7 11.7 6.4 3.6 15.1 13.2 7.6 11.1 6.4 10.1 160.2 7.1 7.4 4.6 63.5 2.1 7.2 2.2 11.2 9.8 5.7 9.9 49.1 7.3 13.1 7.3 7.5 9.1 13.9 23.9 22.7 27.9 19.4 18.3 9.7 17.5 26.9 45.5 51.4 18.7 12.8 14.9 14.1 22.8 23.4 24.1 15.3 11.6 15.8 14.7 19.3 14.4 16.4 32.4 20.9 14.0 13.1 30.1 8.3 24.9 6.1 16.5 20.7 14.9 10.2 12.1 15.8 8.9 35.9 12.7 5.3 7.6 17.0 22.4 33.3 14.5 12.1 14.3 13.3 18.0 22.2 33.4 38.9 11.6 14.9 21.0 20.8 17.7 19.5 24.1 20.6 13.7 15.6 11.8 17.6 10.9 69.2 4.9 12.1 7.3 7.5 13.1 5.9 9.9 6.5 6.0 11.1 7.0 5.9 6.9 2.6 7.3 10.3 49.1 7.2 9.1 51.4 72.8 13.4 93.8 78.4 40.7 86.7 49.0 66.7 63.5 14.9 10.1 20.1 16.4 14.8 20.3 11.3 20.4 13.4 22.7 33.2 5.9 26.2 106.1 40.0 1.0 17.9 18.3 0.0 37.1 41.6 27.2 18.5 9.2 25.9 34.6 47.7 18.9 18.4 13.2 2.8 35.9 14.9 52.3 31.5 12.9 73.9 30.9 17.3 33.9 48.5 23.1 32.3 36.5 3.9 13.0 16.6 10.9 18.7 18.8 16.6 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3231 "pancreas: 3541.6" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 8426.3" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AN3-CA: 16.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" NA NA 17000000 "CAB025197: , HPA021836: AB_1846005, HPA052215: AB_2681764" "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.0 3541.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.3 0.0 0.3 0.0 1.9 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 3.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 5.0 13.2 1.2 0.0 0.0 0.0 8426.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.9 0.0 0.0 77.5 0.0 2.3 847.8 0.0 0.7 0.0 0.0 0.0 0.0 0.5 2.4 0.0 1.4 0.0 0.0 0.0 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266827-130289798 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 529 "pancreas: 1357.9" "Cell type enriched" "Detected in some" 6 "Exocrine glandular cells: 4303.0" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.5;CACO-2: 7.5;RH-30: 6.2;SCLC-21H: 3.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 1357.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 0.1 2.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 4.5 0.0 0.1 0.0 0.0 0.0 0.7 0.0 7.5 0.0 0.0 1.0 0.0 0.6 0.0 1.4 0.0 0.1 1.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.4 0.0 6.2 0.1 0.1 0.7 3.4 0.0 0.2 0.0 2.1 0.3 0.0 0.2 0.0 0.0 1.1 0.8 0.6 0.0 0.7 0.2 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.7 6.6 3.8 0.0 0.8 0.0 4303.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.0 24.4 0.0 2.8 764.8 8.6 0.0 0.0 0.3 0.0 0.0 0.3 1.5 0.1 0.2 0.0 0.2 0.1 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865256-148897196 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.7" "Cell type enriched" "Detected in some" 15 "granulocytes: 4120.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1118 "basophil: 111.7" "Lineage enriched" "Detected in single" 1118 "granulocytes: 111.7" "Cell line enriched" "Detected in some" 43 "HEL: 81.5" "Low region specificity" "Detected in single" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 12.4 0.6 0.4 12.0 0.4 5.6 6.2 0.4 0.5 25.4 14.1 0.8 4.4 7.1 14.1 21.2 16.5 3.7 50.9 4.5 0.4 0.2 5.8 2.8 37.3 15.2 0.4 0.4 2.0 7.2 0.7 0.8 1.3 0.5 37.3 16.4 8.5 8.8 5.8 1.4 12.7 20.2 24.3 0.4 1.0 13.7 7.1 0.4 3.6 1.4 9.9 7.1 14.0 8.9 0.0 0.0 111.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 81.5 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 111.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.5 0.4 29.8 269.3 0.0 0.2 1.4 0.0 0.2 0.0 16.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.6 0.1 4120.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.3 CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 590 "pancreas: 3628.4" "Cell type enriched" "Detected in some" 7 "Exocrine glandular cells: 6332.0" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC diff: 2.8;EFO-21: 2.9;HDLM-2: 3.1;U-2 OS: 5.2;U-251 MG: 1.5;U-266/84: 2.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" NA NA 6600000 "CAB026158: , HPA038069: AB_2675816, HPA046340: AB_2679628" "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" 0.2 1.7 0.1 0.1 0.2 0.0 0.7 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.2 3628.4 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.7 0.2 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 1.8 1.1 6.1 1.0 3.1 3.5 0.9 0.0 0.0 0.0 0.0 2.8 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 0.0 0.0 0.1 3.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 5.2 0.0 1.5 0.0 2.4 0.6 0.0 0.0 0.0 6.1 0.7 1.1 3.0 0.9 2.2 0.9 1.3 2.6 0.3 1.8 0.9 3.5 4.5 3.1 1.0 1.1 0.6 0.9 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 9.9 0.1 0.0 0.0 6332.0 0.0 1.4 6.8 0.0 0.0 0.8 0.0 158.6 0.0 0.0 1.9 0.6 0.0 0.0 31.5 0.0 0.0 954.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.0 0.1 CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053195-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "liver: 246.8" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1070.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 268.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 76 "Hep G2: 62.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA004146 Approved "Secreted to blood" NA NA 14000000000 "HPA004146: AB_1078397" "unprognostic (3.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.89e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (3.17e-2)" "unprognostic (4.83e-2)" "unprognostic (3.20e-3)" "unprognostic (1.34e-1)" "unprognostic (7.10e-2)" "unprognostic (3.34e-2)" "unprognostic (9.61e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 246.8 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.5 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 62.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.4 0.2 0.5 0.4 0.5 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 24.8 0.0 0.0 0.0 0.0 0.0 127.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1070.7 0.1 0.0 0.0 16.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378905-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cholangiocytes: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 19.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052796, HPA055465" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear speckles" NA NA 930000 "Nucleoplasm, Nuclear speckles" "Nuclear membrane" "HPA052796: AB_2681953, HPA055465: AB_2682823" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" 16.4 8.0 9.8 12.3 12.4 18.1 17.9 9.1 13.3 28.6 16.2 18.5 10.1 12.9 12.6 10.1 10.0 15.2 33.6 10.5 12.8 10.4 13.4 26.8 20.0 14.2 22.1 11.4 7.8 14.7 21.2 14.9 22.3 13.9 11.4 13.3 7.5 59.7 7.9 10.0 7.8 22.0 15.1 25.9 7.9 24.6 25.0 13.5 5.8 37.2 7.7 10.0 11.5 11.6 0.4 3.4 19.3 5.5 2.1 3.8 2.5 12.2 18.7 16.2 16.7 16.9 32.2 5.8 16.9 24.8 11.7 14.5 21.9 7.9 1.5 21.6 19.4 14.9 8.8 10.5 21.4 19.9 5.8 15.0 3.5 11.5 13.5 20.6 22.7 9.2 57.4 9.6 15.0 14.6 19.6 23.8 5.3 6.7 18.1 9.4 2.4 7.3 6.2 4.5 28.2 4.3 7.0 18.8 4.7 22.0 14.0 4.1 10.3 20.2 17.5 8.8 19.8 16.5 15.8 28.3 11.7 7.7 18.2 16.1 7.3 15.2 5.2 15.0 14.9 9.9 2.8 5.5 6.4 3.4 2.8 3.8 0.2 1.7 2.8 3.4 0.4 1.4 1.7 19.3 2.1 2.3 0.4 1.1 2.5 9.8 12.4 9.1 13.3 12.8 10.4 22.1 11.4 13.9 13.5 29.8 19.2 7.5 28.1 19.6 23.1 10.4 178.3 18.7 27.3 27.9 43.2 20.5 1.7 21.2 75.9 48.4 31.6 0.0 21.4 9.1 26.2 58.6 24.2 67.2 14.9 44.5 31.0 51.0 34.9 41.5 15.5 20.5 28.7 10.0 69.1 11.1 30.2 20.1 15.2 17.7 35.0 0.0 22.6 15.6 24.2 16.3 20.1 20.8 31.5 38.6 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498320 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 203.7" "Group enriched" "Detected in many" 4 "Bipolar cells: 533.2;Cone photoreceptor cells: 585.1;Glandular cells: 402.2;Intestinal endocrine cells: 564.2;Leydig cells: 463.7;Muller glia cells: 511.1;Peritubular cells: 583.8;Rod photoreceptor cells: 443.0;Sertoli cells: 840.8;Smooth muscle cells: 614.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "Hep G2: 49.0;SCLC-21H: 69.0;SiHa: 101.3;SuSa: 59.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 470000 Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 27.7 33.8 123.1 4.4 135.5 0.9 21.5 82.9 203.7 10.7 9.6 31.6 5.3 5.0 13.3 94.3 16.4 15.7 14.0 19.6 116.9 56.3 12.0 6.3 11.0 7.6 56.9 70.7 23.4 35.5 33.9 40.0 2.2 53.0 66.5 8.8 13.2 12.0 20.1 11.0 5.5 6.2 18.5 40.5 2.8 19.2 30.4 53.3 0.9 40.7 4.3 7.7 6.3 9.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.3 8.9 1.7 7.1 0.7 0.4 0.0 3.6 1.3 2.9 0.0 0.0 0.0 2.6 0.0 0.3 0.2 3.4 0.7 0.7 0.0 13.0 0.0 3.6 49.0 0.5 0.0 0.0 17.3 3.6 0.0 0.0 17.2 0.0 0.0 0.0 0.3 1.8 2.4 0.0 0.4 5.6 0.0 2.0 0.0 0.0 0.1 0.1 0.5 69.0 22.8 101.3 12.7 0.0 59.1 7.6 0.3 0.0 2.7 7.0 0.2 0.2 3.9 0.0 0.3 2.6 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 123.1 135.5 82.9 82.2 116.9 56.3 56.9 70.7 53.0 53.3 0.0 9.3 0.0 67.8 23.2 533.2 32.3 40.8 0.0 3.4 21.0 585.1 0.4 0.0 15.1 5.5 57.1 1.6 0.0 1.5 0.1 129.4 402.2 0.0 7.9 0.8 66.7 564.2 115.4 9.2 11.5 463.7 12.5 82.7 1.8 12.7 511.1 19.3 2.9 583.8 9.6 443.0 840.8 614.9 17.7 9.6 18.2 0.7 1.9 3.7 11.3 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.1" "Cell type enhanced" "Detected in many" 11 "Alveolar cells type 1: 333.5;Sertoli cells: 750.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 15.5;myeloid DC: 11.9" "Group enriched" "Detected in many" 5 "dendritic cells: 11.9;monocytes: 15.5" "Cell line enhanced" "Detected in many" "ASC diff: 29.5;ASC TERT1: 21.0;HSkMC: 37.8;SiHa: 27.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 5000000 Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 56.1 6.6 3.8 5.4 7.0 1.1 37.2 1.2 4.9 6.5 12.9 13.2 0.9 1.6 10.7 6.1 4.1 6.4 6.5 2.9 5.3 3.0 22.1 11.6 24.1 13.0 10.9 4.3 7.5 7.8 3.2 1.0 27.9 5.5 6.2 10.8 2.7 3.2 1.7 8.2 13.0 3.7 2.5 6.7 11.4 5.9 5.8 9.3 1.1 5.1 3.5 4.5 4.4 4.4 2.8 11.9 1.3 15.5 0.3 1.3 4.7 0.0 1.5 0.0 0.0 29.5 21.0 0.3 3.9 0.4 0.7 0.9 1.2 1.6 0.2 3.9 0.5 1.7 0.0 0.5 1.0 1.7 0.0 1.0 0.0 6.4 0.1 0.1 0.4 0.7 37.8 0.2 0.4 0.8 3.5 0.0 0.1 0.0 0.0 3.0 0.6 0.0 0.2 0.6 0.0 2.1 1.2 0.2 0.0 2.9 2.3 0.1 0.0 27.7 4.3 3.3 2.3 0.4 10.3 0.1 0.5 3.2 0.2 0.0 0.1 0.1 5.1 1.7 5.2 2.3 0.3 15.5 0.1 0.1 10.2 0.0 1.4 1.2 0.0 11.9 2.8 0.7 0.1 1.3 0.3 4.7 0.8 1.3 4.7 3.8 7.0 1.2 4.9 5.3 3.0 10.9 4.3 5.5 9.3 333.5 253.0 5.4 2.5 11.0 2.5 1.6 147.7 26.8 114.9 48.8 0.0 22.1 24.9 48.5 13.5 7.1 69.0 0.0 179.6 47.4 3.8 40.7 105.6 33.4 132.7 0.0 10.4 90.2 236.7 12.1 97.2 57.6 10.1 10.8 28.4 65.4 68.6 50.7 74.3 67.7 4.3 750.3 107.2 0.5 1.9 8.7 144.2 7.9 29.3 2.4 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081877 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 127 "liver: 76.8" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 24.6" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 56.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 22000000000 "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 0.1 0.0 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12804017 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 93.6" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 85.5;Syncytiotrophoblasts: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 93.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 45.3;HMC-1: 42.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 380000 Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: AB_2677774" "prognostic unfavorable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favorable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 10.9 11.5 8.3 14.3 14.3 9.5 8.5 2.7 11.8 9.2 13.8 20.8 7.4 16.3 8.2 6.2 23.1 7.2 8.9 10.7 11.2 9.5 26.2 31.4 10.4 21.2 20.7 7.7 6.4 4.1 4.3 6.5 36.6 17.6 9.1 11.9 10.2 15.1 7.3 6.4 6.8 20.5 10.0 22.1 27.4 8.1 18.2 13.1 5.8 11.1 8.4 16.9 9.8 9.6 1.5 23.1 93.6 43.7 1.9 1.8 14.6 1.5 9.5 1.0 2.5 4.0 8.5 0.1 17.4 4.7 9.3 7.6 4.6 4.9 2.3 18.0 12.6 4.1 0.1 0.0 4.3 9.7 5.3 2.6 19.7 1.4 45.3 2.5 0.0 42.8 8.5 0.9 0.8 6.7 0.0 13.9 3.2 6.8 1.4 22.8 1.9 1.7 9.1 2.8 0.7 1.3 3.7 6.1 4.9 14.1 3.0 5.0 3.3 0.0 15.8 6.2 5.2 3.4 4.3 20.8 13.5 2.8 0.0 0.0 0.0 0.3 3.6 3.0 10.0 2.8 6.1 30.6 19.3 1.3 43.7 1.1 1.5 1.1 1.4 23.1 1.0 0.3 0.8 93.6 1.9 40.6 5.6 1.8 14.6 8.3 14.3 2.7 11.8 11.2 9.5 20.7 7.7 17.6 13.1 8.9 18.4 13.0 2.9 4.0 3.6 8.2 7.6 10.7 6.8 14.0 7.9 85.5 51.4 33.8 2.3 11.3 13.5 0.0 10.9 10.0 9.3 3.3 52.1 38.5 44.3 9.5 5.8 7.4 74.6 2.3 14.4 42.4 6.8 27.9 7.5 12.5 30.7 13.6 22.6 51.8 5.5 25.8 4.2 1.6 11.5 4.0 110.3 7.4 10.6 1.4 CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 140.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" NA NA "Lipid droplets" "HPA037439: AB_10601264, HPA066466: AB_2732745" "unprognostic (7.11e-2)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "prognostic favorable (6.45e-4)" "unprognostic (3.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.61e-2)" "unprognostic (1.50e-2)" "unprognostic (2.98e-1)" "unprognostic (9.90e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.37e-1)" "unprognostic (2.77e-3)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (9.97e-2)" "unprognostic (2.02e-2)" 27.1 23.1 21.4 22.4 21.0 24.2 38.8 21.8 26.6 25.3 24.8 26.6 16.7 20.8 31.2 22.8 26.6 27.3 18.8 29.0 21.5 12.9 23.8 20.6 26.5 39.4 24.7 17.1 31.1 27.9 30.7 26.1 30.4 20.5 25.2 27.9 20.4 23.0 23.8 140.1 35.5 30.9 26.7 25.6 38.3 24.3 26.6 24.3 43.8 26.0 31.5 34.1 22.4 26.7 13.0 17.3 18.3 11.8 7.2 11.2 3.8 38.9 58.3 32.8 35.2 51.4 63.3 24.9 29.2 48.9 47.1 40.6 27.8 27.3 36.1 31.1 52.1 32.9 32.7 43.0 45.0 52.7 53.6 36.5 25.2 39.2 47.9 47.7 28.6 47.7 51.0 54.8 53.9 57.6 48.5 50.1 35.8 22.5 26.8 44.2 24.6 31.9 30.7 22.8 34.9 24.8 38.9 29.2 28.8 37.4 20.5 12.6 36.2 23.2 23.3 31.1 33.9 22.0 23.6 28.5 34.4 29.6 27.4 54.8 23.2 20.2 18.5 44.2 39.6 35.5 6.3 11.8 18.3 10.5 11.7 8.5 13.0 10.1 11.0 8.4 12.4 7.8 11.2 15.6 7.2 7.7 17.3 9.6 3.8 21.4 21.0 21.8 26.6 21.5 12.9 24.7 17.1 20.5 24.3 23.8 21.0 48.6 41.4 41.9 42.6 10.8 30.6 9.4 25.0 38.4 21.6 54.3 10.0 54.2 3.7 44.4 63.2 0.0 73.6 98.0 42.3 51.3 19.7 33.8 80.8 28.6 70.8 40.5 83.4 5.0 53.5 53.1 27.0 36.9 73.9 45.9 67.9 46.0 44.2 29.3 28.2 25.8 33.0 14.6 35.6 58.6 69.6 36.2 58.8 56.2 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679801-79756623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 89.2;Late spermatids: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 6.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 10.6 8.2 6.2 12.8 9.5 21.8 9.5 7.5 12.2 7.9 12.0 14.4 5.3 13.4 11.9 9.3 11.4 9.8 10.0 6.6 6.8 5.7 8.9 13.4 10.2 14.4 12.3 5.1 7.7 13.4 4.6 7.9 10.6 9.1 9.1 6.2 8.4 10.6 8.3 12.1 20.9 13.8 8.2 6.8 15.3 12.2 27.2 10.6 26.2 9.4 8.8 14.8 11.4 8.9 0.7 1.5 6.4 1.0 2.4 2.0 0.5 8.1 9.1 5.1 7.2 4.1 3.4 16.9 5.5 4.0 5.0 5.0 6.0 5.2 10.4 2.6 3.6 6.1 10.0 4.3 5.7 2.1 9.6 7.8 5.4 4.5 8.1 5.9 23.7 13.3 5.7 5.5 5.4 2.5 3.1 6.0 7.9 6.5 5.3 1.9 7.3 15.8 18.7 7.9 2.7 12.2 12.3 6.7 12.5 3.7 8.5 7.9 8.1 6.5 6.5 8.7 4.0 5.2 13.9 8.2 8.7 12.6 3.4 5.9 4.5 16.6 10.3 7.4 12.0 6.1 0.0 1.0 6.4 1.3 0.9 1.1 0.7 1.0 2.0 1.5 0.4 1.3 0.7 2.7 2.4 0.9 0.2 0.3 0.5 6.2 9.5 7.5 12.2 6.8 5.7 12.3 5.1 9.1 10.6 0.0 2.6 3.7 4.2 7.6 9.8 3.1 5.1 6.7 3.4 3.5 13.7 7.8 1.7 4.4 89.2 5.2 11.7 23.3 6.2 6.5 4.2 8.1 6.9 5.5 7.7 22.3 5.8 7.4 7.3 97.9 7.2 9.5 6.8 0.0 15.1 7.8 8.0 14.4 9.9 5.7 14.3 0.0 5.1 5.9 6.8 8.8 15.9 13.3 10.6 11.5 CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm NA NA Nucleoplasm "HPA062654: AB_2684819" "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" 32.9 22.5 15.9 21.9 13.9 19.9 41.1 12.2 16.4 34.8 30.7 27.6 31.8 24.2 34.5 30.7 31.3 30.9 43.4 25.9 15.5 8.6 34.1 47.5 30.2 33.2 15.0 13.1 44.9 50.8 28.8 12.6 71.3 15.9 41.5 19.8 35.4 34.3 31.5 23.2 30.5 41.3 33.7 12.4 39.1 34.2 15.1 16.1 33.2 41.0 27.2 29.9 32.5 28.4 3.4 6.6 29.3 12.4 6.7 11.0 7.5 10.3 13.3 7.8 25.8 21.4 20.0 29.6 13.9 20.0 13.4 11.7 17.3 25.8 6.2 12.1 24.5 9.2 21.1 11.6 16.7 6.9 22.2 9.1 23.8 16.3 23.1 25.7 14.6 33.4 22.7 20.4 10.2 11.5 21.3 19.7 9.8 19.3 22.4 14.2 28.9 12.8 42.7 5.5 16.5 13.7 17.7 11.1 13.5 17.1 12.7 5.2 13.1 12.1 26.4 13.1 10.4 14.5 35.2 17.2 21.4 13.1 16.3 6.0 14.4 9.3 14.7 19.1 13.9 11.8 20.3 12.4 29.3 11.0 10.2 7.1 3.4 6.7 7.0 6.6 3.2 4.3 5.7 24.5 6.7 10.4 2.3 5.6 7.5 15.9 13.9 12.2 16.4 15.5 8.6 15.0 13.1 15.9 16.1 41.7 40.2 27.7 26.3 24.3 14.0 27.9 45.9 9.4 20.5 29.6 2.0 35.7 28.2 31.7 1.5 43.6 72.4 46.7 37.2 35.9 36.1 31.8 17.4 49.9 35.0 6.4 20.8 58.3 79.9 2.0 55.0 36.2 32.1 26.2 44.5 46.7 32.1 35.1 41.4 42.5 24.7 25.8 34.0 1.6 4.7 17.8 45.4 46.7 37.6 26.7 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846739 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 169.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria NA NA Nucleoplasm Mitochondria "HPA052607: AB_2681883" "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 44.5 43.6 28.2 31.6 34.8 17.6 39.6 57.1 33.4 49.0 48.4 36.7 47.7 24.4 50.4 32.9 38.0 41.9 37.7 34.6 31.2 16.5 32.8 32.6 51.3 31.3 37.1 19.9 52.5 53.9 33.7 25.4 42.9 31.0 40.5 38.6 29.3 45.8 60.9 48.8 39.9 36.1 44.1 25.7 38.1 43.1 21.0 40.9 62.9 40.1 32.8 33.9 46.1 63.0 7.3 9.3 18.7 9.7 8.2 11.5 7.1 11.0 4.8 23.1 14.7 20.8 35.9 7.7 12.0 22.8 11.9 10.7 6.1 18.1 13.6 13.8 25.5 4.6 8.9 9.6 11.7 12.5 4.5 4.1 18.8 7.4 4.9 19.4 8.5 11.0 34.3 12.4 10.8 9.2 25.6 18.6 8.3 9.8 24.1 5.9 5.1 9.1 5.1 11.7 7.0 6.1 12.2 169.3 17.8 9.3 16.1 4.3 9.6 16.7 9.6 14.4 14.7 17.4 14.9 14.9 10.6 11.6 11.9 4.2 7.2 7.7 16.4 11.9 7.9 8.2 11.5 9.7 14.7 6.9 9.0 8.2 7.3 9.9 8.0 9.3 6.5 11.5 8.7 18.7 8.2 7.7 7.7 6.4 7.1 28.2 34.8 57.1 33.4 31.2 16.5 37.1 19.9 31.0 40.9 68.5 36.0 33.5 41.6 60.0 18.7 31.1 79.0 13.4 23.9 45.4 15.7 36.7 13.3 64.0 44.2 58.1 55.7 0.0 117.0 34.7 57.1 49.1 24.3 49.7 36.0 19.1 46.8 80.4 63.9 111.0 48.1 36.8 40.5 66.7 42.3 41.1 88.4 51.8 45.6 23.9 10.8 71.1 55.2 5.8 25.8 66.6 47.0 40.6 35.4 58.0 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861960-37984469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Peritubular cells: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles NA NA 10000 Vesicles Nucleoplasm "HPA048325: AB_2680359" "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favorable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 12.8 6.3 11.1 7.8 12.4 5.6 22.0 30.2 14.1 15.5 19.9 8.0 25.7 9.3 14.5 18.3 16.8 12.2 37.2 18.9 13.1 5.9 26.7 13.3 19.0 4.9 7.8 9.9 13.7 10.2 8.3 9.4 20.6 6.9 17.5 20.3 15.6 45.5 22.4 12.5 34.8 11.2 21.3 8.1 11.3 19.7 8.1 8.3 2.9 10.0 13.9 6.9 19.6 21.7 0.0 0.2 1.1 0.5 0.0 0.5 5.6 15.8 6.9 2.9 9.0 11.3 16.2 21.4 10.9 13.8 7.6 8.9 10.0 13.0 0.0 6.7 13.5 3.1 13.3 7.0 20.7 6.1 0.0 5.5 9.7 7.4 22.6 10.3 0.0 2.4 8.3 50.9 8.0 9.6 8.6 10.6 4.4 3.1 0.0 12.5 5.0 3.9 0.0 11.8 6.5 1.0 4.4 5.5 0.1 24.3 10.6 2.4 7.5 6.0 10.8 12.2 12.1 10.4 2.6 8.4 5.5 7.7 10.2 6.8 0.2 0.0 0.0 6.1 5.4 10.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 1.1 0.0 0.0 0.0 0.0 5.6 11.1 12.4 30.2 14.1 13.1 5.9 7.8 9.9 6.9 8.3 62.5 19.3 0.0 13.3 26.8 9.6 33.8 71.4 14.7 31.8 22.7 0.0 27.6 19.9 10.8 21.9 17.5 10.3 0.0 4.2 7.7 21.7 12.0 1.1 13.9 6.3 9.5 43.5 19.0 9.5 32.3 66.4 5.5 8.5 0.0 17.7 7.1 10.0 5.8 92.3 14.9 1.6 25.8 22.7 2.8 15.8 25.1 7.9 2.2 29.9 14.2 CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75219000-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2272 "pancreas: 1908.8" "Cell type enriched" "Detected in some" 12 "Exocrine glandular cells: 26371.2" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.4;HDLM-2: 5.0;U-2 OS: 2.5;U-251 MG: 1.6" "Secreted to digestive system" NA NA "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.8 1908.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 6.4 0.0 0.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.2 1.6 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 26371.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 265.1 0.0 0.0 2264.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204096-75207185 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5240 "pancreas: 3761.5" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 45669.7" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.1;HDLM-2: 1.9;U-2 OS: 9.3;U-251 MG: 1.9;U-266/84: 2.6;U-698: 2.4" "Secreted to digestive system" NA NA "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 3761.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 5.1 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 9.3 0.0 1.9 0.1 2.6 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 1.0 0.0 0.0 0.0 45669.7 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.3 0.3 0.0 0.0 376.1 0.0 0.0 8606.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438439-15449242 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 417 "pancreas: 1443.7" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 5617.8" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA046920 Enhanced "Secreted to digestive system" NA NA "HPA046920: AB_2679865" "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.6 1443.7 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.4 3.4 0.7 1.5 0.6 0.1 3.6 0.6 0.5 0.7 0.2 0.0 0.2 0.3 0.4 0.0 0.0 0.0 1.7 0.5 1.1 0.0 0.5 0.5 0.0 0.1 0.2 1.1 0.6 0.4 0.3 0.1 0.9 0.2 1.7 0.3 0.0 0.0 0.0 0.6 0.0 0.7 0.1 1.8 0.2 0.5 1.1 1.7 0.5 0.0 0.0 0.5 0.1 0.3 0.0 0.1 0.4 1.0 0.4 0.2 0.2 0.2 0.3 0.1 0.9 0.4 1.4 0.9 0.3 0.8 1.6 0.3 0.8 0.8 0.3 3.4 0.4 0.4 0.4 0.2 0.2 0.3 0.3 0.6 0.1 1.1 0.3 0.4 1.7 1.5 0.7 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.1 0.0 0.0 5617.8 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.7 41.5 0.0 0.0 1090.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898820 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 125.7" "Cell type enhanced" "Detected in many" 4 "Hofbauer cells: 279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 113.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 18000000 Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 29.0 125.7 12.0 22.8 19.5 22.1 35.3 11.4 30.0 14.1 50.6 17.4 16.2 29.4 18.2 19.3 20.7 12.7 28.0 32.6 11.5 11.6 88.2 43.8 28.4 38.9 12.3 16.1 23.9 19.2 28.3 16.5 47.7 15.7 18.2 50.5 30.1 20.5 15.1 19.3 28.2 40.6 19.6 11.9 38.8 19.7 14.3 11.2 8.0 18.1 24.9 22.4 23.3 18.7 7.0 16.6 81.1 46.1 12.0 31.2 50.0 14.1 14.5 2.7 12.4 113.6 58.9 6.3 20.3 54.2 22.3 29.1 27.3 38.1 3.0 23.6 38.1 84.2 22.6 7.3 13.7 14.0 5.9 6.8 8.0 10.2 47.5 25.3 12.7 33.2 46.7 16.5 14.4 3.2 55.8 24.2 3.9 7.9 46.7 24.1 29.1 3.2 11.8 2.8 21.6 34.6 5.1 14.1 16.8 17.8 12.5 5.5 5.2 33.9 59.3 56.7 7.3 14.5 18.3 22.3 44.8 10.5 25.3 15.9 23.1 29.1 2.1 80.6 16.9 18.4 60.6 46.1 81.1 7.5 26.6 31.2 7.0 12.9 13.2 16.6 3.6 4.7 6.9 24.7 12.0 17.7 6.6 23.9 50.0 12.0 19.5 11.4 30.0 11.5 11.6 12.3 16.1 15.7 11.2 32.8 24.6 40.4 31.0 21.5 54.2 10.9 58.6 22.7 26.1 68.0 56.9 86.8 33.2 172.8 2.3 41.6 257.8 0.0 146.8 91.1 44.1 21.0 9.2 53.3 279.4 44.5 51.9 105.0 166.6 3.6 30.5 81.3 106.3 136.1 70.2 92.8 127.7 92.2 25.8 168.1 30.9 25.8 46.4 6.2 32.4 19.9 120.5 54.2 85.6 31.9 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869448 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 297.0" "Cell type enhanced" "Detected in all" 11 "Hofbauer cells: 2617.6;Kupffer cells: 1392.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 53.1;classical monocyte: 127.4;intermediate monocyte: 97.0;myeloid DC: 68.0;non-classical monocyte: 54.7;plasmacytoid DC: 95.4" "Group enriched" "Detected in all" 5 "dendritic cells: 95.4;granulocytes: 53.1;monocytes: 127.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 239.8;fHDF/TERT166: 139.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 130000000 Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 227.9 42.1 19.6 67.2 24.4 14.7 67.6 14.9 31.4 76.7 49.1 30.1 22.7 29.9 53.2 44.8 54.2 52.4 43.6 120.7 18.3 23.7 95.6 167.8 94.3 175.1 29.1 16.5 44.2 31.6 13.8 21.6 68.7 24.8 42.6 27.9 33.8 63.7 33.6 41.3 22.8 51.2 51.1 35.9 116.4 26.7 21.5 20.4 18.1 297.0 25.9 38.4 56.8 62.2 7.9 95.4 53.1 127.4 5.3 17.1 108.5 6.4 29.5 3.8 16.2 66.6 74.9 11.8 122.8 239.8 43.0 51.0 14.0 38.4 0.1 17.8 139.3 57.7 35.8 5.2 33.9 27.2 3.2 5.0 9.5 3.4 34.5 67.8 2.1 7.1 82.1 46.2 38.9 34.8 74.9 84.1 2.8 7.9 21.7 35.7 5.2 0.8 3.5 3.2 75.8 9.9 3.4 3.8 16.6 13.1 10.2 1.6 9.6 14.2 7.7 64.0 11.7 12.5 6.4 116.4 73.1 24.8 23.4 22.8 21.6 15.7 0.6 83.9 8.2 34.2 53.1 127.4 16.3 5.2 97.0 7.2 7.9 17.1 5.8 68.0 6.1 9.6 4.1 18.5 5.3 54.7 95.4 13.4 108.5 19.6 24.4 14.9 28.0 18.3 23.7 29.1 16.5 24.8 20.4 101.3 205.9 73.7 364.9 48.5 44.4 251.7 175.8 137.9 227.5 108.2 39.3 224.9 23.2 276.8 13.3 119.6 152.5 210.2 211.7 280.5 149.9 239.1 169.3 203.7 2617.6 55.6 148.7 214.9 1392.4 12.2 70.8 859.7 153.5 399.5 80.9 115.8 264.9 108.7 87.4 331.7 35.7 38.8 121.0 4.8 18.5 35.4 543.3 50.7 114.7 284.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88293592-88337787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 218.6" "Cell type enhanced" "Detected in many" 11 "Cytotrophoblasts: 362.7;Hofbauer cells: 897.2;Macrophages: 364.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 111.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 40.7 20.5 6.7 44.5 10.6 12.0 35.3 1.5 5.6 14.0 25.3 7.1 6.2 20.4 16.1 24.0 21.8 16.7 36.6 53.3 6.8 6.5 62.7 18.1 110.1 218.6 12.5 3.6 11.0 24.8 3.8 17.3 43.4 9.4 13.8 33.1 27.0 35.1 5.8 10.0 11.7 28.5 14.2 14.6 86.6 13.5 10.8 9.2 19.5 17.7 25.3 30.0 30.2 16.9 8.5 75.9 52.5 92.6 34.7 42.4 31.2 11.1 11.5 4.5 9.4 12.1 32.9 30.1 76.8 111.7 43.9 31.7 31.1 51.7 17.4 40.9 41.7 10.1 18.1 7.0 32.5 35.0 30.7 12.7 22.7 31.8 35.0 16.2 28.9 15.4 45.8 23.0 33.8 69.4 37.0 43.1 16.9 20.6 21.1 5.3 2.1 13.0 39.9 23.5 75.5 35.6 17.0 4.7 30.9 56.4 18.8 1.2 9.4 12.9 17.1 10.0 27.9 3.8 19.8 20.9 3.0 27.2 20.9 48.8 8.9 12.8 17.7 7.9 60.9 16.6 12.5 32.5 52.5 42.4 69.3 36.5 8.5 19.5 37.8 35.1 4.6 9.9 23.8 37.2 34.7 92.6 75.9 28.4 31.2 6.7 10.6 1.5 5.6 6.8 6.5 12.5 3.6 9.4 9.2 20.8 83.9 64.9 5.0 26.8 1.0 2.5 56.0 80.3 93.3 38.4 0.0 362.7 24.9 14.0 1.2 41.8 29.0 0.0 79.6 130.7 85.3 3.1 72.8 14.0 897.2 0.0 10.9 24.5 290.2 4.0 183.8 364.2 45.5 139.7 15.7 0.6 35.1 69.1 24.1 150.6 0.6 58.2 183.3 3.0 11.5 23.7 190.1 167.5 36.3 14.2 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 11 "Enterocytes: 1407.0;Hofbauer cells: 3678.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 190.9;hTERT-RPE1: 255.7;SK-BR-3: 182.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 540000000 "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 151.9 148.7 21.4 32.8 27.0 83.7 67.7 18.6 47.4 56.3 59.3 41.4 41.9 61.6 25.9 48.2 46.2 34.2 90.0 86.0 25.3 27.6 150.5 163.5 102.6 81.1 49.6 25.7 41.2 62.3 21.3 24.9 56.1 42.8 33.9 33.7 234.4 64.1 42.3 76.2 50.8 90.9 23.3 36.7 87.6 47.0 29.8 29.7 21.1 36.3 42.9 41.4 64.6 43.5 4.9 22.7 51.1 83.8 28.4 26.1 58.7 13.8 37.5 4.3 18.0 54.9 18.8 7.0 10.3 32.0 13.8 16.4 9.3 190.9 3.3 26.6 26.5 103.7 74.7 6.2 11.5 3.8 14.3 13.6 5.1 7.1 11.6 58.0 11.8 54.6 30.2 50.5 7.4 13.7 255.7 10.1 4.4 6.1 20.6 24.4 51.1 3.0 6.6 10.2 56.8 15.1 4.3 5.3 12.5 48.7 43.4 6.0 5.9 12.2 182.5 34.6 6.5 71.4 16.3 12.7 42.1 6.4 5.8 16.4 28.3 35.5 2.1 61.3 31.9 35.2 29.0 83.8 25.2 26.1 47.6 15.1 4.9 12.2 18.3 22.7 3.2 14.3 18.3 51.1 28.4 38.5 19.2 13.5 58.7 21.4 27.0 18.6 47.4 25.3 27.6 49.6 25.7 42.8 29.7 104.2 261.1 102.1 219.0 64.0 155.9 226.4 366.9 115.1 126.3 519.9 104.1 198.5 92.9 592.1 2.7 92.6 1407.0 70.0 321.5 138.5 112.5 108.8 466.1 497.1 3678.7 249.5 153.3 833.5 1087.5 9.0 100.4 573.5 215.9 205.6 341.0 186.6 426.0 610.2 120.6 259.1 69.6 109.9 103.0 22.4 56.8 71.8 394.2 188.4 260.3 345.7 CTSE ENSG00000196188 "Cathepsin E" P14091 1 206009264-206023909 "Enzymes, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 57.9;intestine: 47.3;stomach 1: 153.0" "Cell type enhanced" "Detected in some" 14 "Alveolar cells type 1: 98.3;Club cells: 77.3;Exocrine glandular cells: 240.3;Pancreatic endocrine cells: 151.8;Paneth cells: 175.6" "Group enriched" "Detected in many" 8 "lung cancer: 68.8;pancreatic cancer: 297.4;stomach cancer: 200.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 44 "OE19: 201.7" "Not detected" "Not detected" "HPA012940, CAB032687" Enhanced "Intracellular and membrane" NA NA "CAB032687: AB_637901, HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" 0.2 0.1 0.1 3.7 0.1 3.0 0.1 0.1 0.1 0.1 47.3 0.3 0.8 29.3 0.1 0.7 0.6 0.5 57.9 0.3 0.1 0.1 0.2 0.2 24.9 0.0 0.1 0.0 0.1 2.2 0.0 0.5 0.0 0.1 1.3 3.2 0.0 0.1 0.0 0.1 0.1 29.7 0.0 0.1 0.2 153.0 0.1 0.0 0.3 4.2 0.0 1.1 1.8 0.4 0.2 0.7 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.7 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 98.3 20.9 0.0 0.1 0.0 0.0 0.4 17.8 13.4 77.3 0.0 0.0 0.0 0.0 44.2 0.0 0.0 5.1 23.3 240.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.0 2.8 8.1 0.0 151.8 175.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.2 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563463-66568841 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 256.1;Muller glia cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cells: 7.5;T-cells: 9.7" "Cell line enhanced" "Detected in many" "HSkMC: 28.4;SK-MEL-30: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Uncertain "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3600000 Cytosol "Vesicles, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 28.1 29.4 24.7 8.0 29.0 1.8 31.1 38.4 47.1 37.3 23.8 32.6 25.2 5.8 38.1 29.8 12.9 34.3 37.3 34.5 25.3 20.5 29.8 45.4 17.3 8.5 28.0 26.0 68.2 23.1 42.6 15.9 20.2 25.4 32.3 8.1 35.0 35.5 37.8 35.8 19.7 9.4 34.6 22.4 10.4 17.8 37.1 30.1 0.8 18.6 14.2 6.3 22.2 21.5 2.1 1.1 0.5 0.7 7.5 9.7 2.4 0.1 9.3 5.0 13.0 21.5 8.7 3.6 6.6 16.7 6.8 4.8 0.0 8.3 0.0 11.1 14.4 0.3 0.9 8.6 2.8 3.6 2.2 0.0 0.3 3.8 0.0 12.0 0.1 5.1 28.4 9.7 1.5 1.1 20.3 4.3 2.7 2.9 1.5 8.5 1.9 0.1 1.1 0.6 5.0 3.4 0.0 1.9 1.6 6.1 0.2 6.0 6.5 17.5 2.0 52.8 0.5 13.3 0.8 2.8 2.8 2.7 3.2 0.7 8.9 0.1 0.0 6.6 0.1 4.1 0.0 0.7 0.4 6.5 0.7 7.0 2.0 5.6 7.3 0.8 2.1 9.7 5.5 0.5 7.5 0.3 1.1 1.7 2.4 24.7 29.0 38.4 47.1 25.3 20.5 28.0 26.0 25.4 30.1 11.9 14.1 3.4 58.6 35.3 99.1 43.9 35.7 2.7 5.7 34.9 39.3 22.1 13.3 8.5 123.6 24.1 0.0 0.0 6.6 8.1 75.7 48.4 9.2 51.3 13.1 127.1 11.5 49.7 15.8 256.1 134.9 9.9 148.5 2.8 3.1 186.2 8.9 1.9 114.5 30.7 63.2 77.6 43.8 164.4 36.6 22.1 19.8 19.2 3.0 26.5 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573522-24576260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "bone marrow: 450.3" "Cell type enriched" "Detected in some" 9 "granulocytes: 500.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.5;memory CD8 T-cell: 3.5;myeloid DC: 5.1;naive CD8 T-cell: 1.8;neutrophil: 7.1;NK-cell: 5.2;plasmacytoid DC: 5.7" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "THP-1: 448.1" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" NA NA 67000 "CAB000110: , HPA047737: AB_2680140" "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.91e-4)" 15.1 0.5 0.0 6.0 0.0 450.3 6.0 0.0 0.6 10.0 5.1 0.0 2.8 1.1 6.2 19.7 6.4 0.8 16.7 23.4 0.0 0.0 2.1 2.0 9.2 3.7 0.0 0.0 1.5 3.4 0.8 0.5 3.0 0.0 8.2 3.2 2.6 6.3 6.9 1.1 19.5 8.9 14.9 0.0 10.7 3.2 2.8 0.0 15.6 0.5 12.0 5.1 2.9 3.3 0.0 5.7 7.1 6.5 5.2 3.5 12.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 448.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 66.4 0.0 0.0 6.5 0.0 1.1 1.0 0.0 0.0 1.0 3.5 5.1 0.0 0.0 1.8 7.1 5.2 0.0 5.7 0.0 12.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 11.9 58.0 0.0 0.0 5.7 0.0 0.6 0.0 1.4 4.5 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.1 1.0 0.0 500.2 0.0 0.2 0.0 0.0 0.0 0.0 4.7 0.0 4.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.4 0.0 0.0 0.0 0.0 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 82.6" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 1152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 42.8" "Group enriched" "Detected in all" 5 "B-cells: 20.6;dendritic cells: 41.2;monocytes: 42.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 43.1;HaCaT: 31.5;OE19: 31.0;RT4: 119.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 10000000 "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 16.7 10.6 9.5 24.2 7.0 5.4 23.9 4.5 9.8 25.1 11.4 17.7 14.7 10.6 10.3 17.1 7.8 13.1 29.2 16.5 14.8 6.7 66.7 18.7 82.6 65.4 12.1 11.6 14.6 25.8 12.3 6.5 7.7 9.4 18.6 6.6 6.7 15.4 15.9 7.0 13.5 16.6 9.8 10.8 20.3 15.6 6.7 15.7 6.6 8.5 4.8 34.8 39.6 13.5 20.6 41.2 1.4 42.8 1.3 7.6 27.3 16.2 1.1 0.4 4.8 1.1 0.0 5.3 1.6 0.6 2.8 1.5 7.1 43.1 5.7 1.8 0.1 3.1 31.5 2.0 7.8 2.3 24.0 0.1 0.1 0.2 16.5 1.7 0.0 1.1 0.8 2.2 0.0 0.0 11.8 0.2 0.7 11.6 0.0 3.9 1.7 3.7 10.0 1.2 31.0 0.3 0.0 0.3 0.9 9.9 119.7 0.5 1.2 7.0 3.9 9.7 2.3 1.6 5.4 2.2 0.0 1.0 0.0 0.7 0.1 12.4 3.1 0.0 10.5 1.7 0.0 42.8 0.4 1.4 28.3 7.6 20.6 4.1 2.1 41.2 12.0 0.4 0.7 1.4 1.3 17.0 4.2 3.1 27.3 9.5 7.0 4.5 9.8 14.8 6.7 12.1 11.6 9.4 15.7 220.3 1152.3 144.6 210.0 21.5 0.8 25.2 351.6 270.4 197.9 349.0 3.9 16.6 71.3 153.3 17.1 109.7 15.8 0.0 128.8 33.6 30.0 89.1 30.2 82.9 261.0 0.0 8.7 15.4 160.1 15.9 67.6 392.5 75.9 476.1 19.5 21.1 69.6 11.5 5.6 352.9 5.6 19.4 17.8 5.0 52.9 16.3 19.6 25.4 37.0 308.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150796208-150808323 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 104.1" "Cell type enhanced" "Detected in many" 11 "Basal keratinocytes: 61.1;Leydig cells: 110.1;Melanocytes: 92.8;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 6.7" "Lineage enriched" "Detected in many" 6 "monocytes: 6.7" "Group enriched" "Detected in some" 8 "ASC diff: 205.0;ASC TERT1: 75.1;BJ hTERT+: 165.6" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 104.1 2.4 1.2 6.5 1.6 1.3 79.3 2.4 2.3 70.6 23.6 2.2 10.1 2.7 72.5 25.9 26.5 12.5 53.4 14.7 1.1 1.1 3.4 1.8 8.7 10.4 1.1 1.7 25.4 2.9 0.3 3.0 30.6 2.6 24.2 11.5 56.0 10.9 6.8 19.9 44.0 11.0 26.9 2.0 5.6 8.6 24.1 0.9 1.1 7.1 13.2 10.7 38.0 48.2 0.1 1.0 1.0 6.7 0.5 1.2 1.8 0.1 0.1 0.4 0.3 205.0 75.1 0.2 5.8 165.6 0.4 0.9 0.0 0.1 0.1 0.2 11.4 0.0 0.2 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.0 1.1 0.1 0.4 14.9 0.5 4.6 0.1 13.1 0.6 0.1 0.0 0.5 0.4 0.3 0.0 0.7 1.1 0.2 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.7 0.3 0.0 3.1 0.9 0.2 0.2 0.4 0.2 0.1 0.2 0.3 0.7 0.5 1.1 17.4 0.0 1.0 0.0 6.7 1.0 0.7 3.4 0.2 0.0 0.6 0.2 0.4 0.1 0.3 0.5 0.6 0.5 2.0 1.0 1.2 1.8 1.2 1.6 2.4 2.3 1.1 1.1 1.1 1.7 2.6 0.9 3.0 5.8 0.0 0.5 61.1 8.4 1.2 2.5 2.7 5.7 3.5 3.9 1.0 0.0 1.1 0.8 5.2 1.1 0.0 0.2 1.9 31.5 0.9 0.0 0.0 19.2 3.2 1.2 9.8 3.7 1.7 110.1 6.6 92.8 2.8 1.9 2.4 1.3 0.6 140.7 0.0 7.8 12.9 47.6 1.4 0.7 51.7 0.8 0.0 0.9 0.5 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87725519-87731393 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 237.0" "Cell type enhanced" "Detected in all" 8 "Cytotrophoblasts: 935.7;Extravillous trophoblasts: 843.2;Hofbauer cells: 1004.8;Ito cells: 672.8;Syncytiotrophoblasts: 1290.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 31.0;non-classical monocyte: 44.3" "Lineage enriched" "Detected in many" 10 "monocytes: 44.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 201.6;HSkMC: 93.2" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 60.3 21.5 10.4 27.2 24.6 18.4 23.3 6.9 12.3 14.8 23.2 14.1 13.7 9.0 24.1 22.3 11.4 25.7 20.7 37.7 10.7 11.4 65.4 98.0 53.1 80.5 18.9 7.7 25.0 14.3 18.8 18.0 237.0 18.4 19.4 13.0 23.2 22.0 23.5 29.3 9.1 12.0 36.6 16.1 108.1 17.5 14.1 15.7 6.8 19.2 9.4 10.1 41.3 26.5 0.0 1.7 0.1 44.3 0.0 4.3 2.4 6.4 37.4 2.6 4.4 47.1 201.6 15.7 20.8 60.7 17.9 22.4 3.6 5.9 0.0 9.8 26.9 56.7 5.5 3.4 6.8 14.8 0.1 3.3 1.1 10.6 8.7 30.5 0.0 4.5 93.2 11.4 29.2 11.4 15.6 14.1 0.0 12.1 0.0 25.7 10.8 0.0 0.7 4.9 10.1 7.1 1.5 1.5 0.0 12.5 3.4 3.7 4.6 4.3 9.8 23.9 15.6 1.1 7.4 22.0 16.0 8.7 58.4 8.8 1.6 6.0 0.0 58.7 0.0 5.2 0.1 3.5 0.1 0.0 31.0 0.0 0.0 1.8 0.0 1.7 0.0 4.3 0.3 0.1 0.0 44.3 0.1 0.3 2.4 10.4 24.6 6.9 11.7 10.7 11.4 18.9 7.7 18.4 15.7 38.7 60.6 38.5 79.1 33.5 37.4 87.3 84.1 56.2 38.7 71.5 17.7 935.7 23.2 77.5 3.5 75.9 8.6 46.7 82.1 843.2 226.1 43.7 27.8 100.7 1004.8 12.7 11.1 672.8 182.1 10.4 145.3 481.4 60.8 19.8 7.7 78.6 55.2 2.9 176.0 107.8 35.6 90.5 103.2 144.4 46.2 29.6 1290.9 15.3 8.8 43.0 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155924118-155953917 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 12.5;HSkMC: 14.8;Karpas-707: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 24000 "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 13.7 16.4 11.9 12.6 12.0 1.8 14.9 3.7 12.4 16.0 18.5 11.6 10.2 13.3 19.3 27.3 10.8 15.6 16.9 19.7 9.7 8.6 21.2 41.6 26.4 19.4 10.2 6.7 16.3 10.7 13.6 9.4 18.7 9.7 16.1 9.8 24.0 13.8 16.8 5.9 6.2 27.5 14.4 11.4 19.3 10.8 9.0 7.7 5.5 17.1 10.2 10.3 12.4 12.5 7.0 8.9 5.3 14.8 12.0 10.9 8.9 0.3 0.2 1.5 1.6 5.7 12.5 0.0 3.6 7.2 1.3 1.8 0.0 4.6 0.0 0.7 2.4 0.4 0.0 0.0 0.3 0.9 5.3 0.1 0.4 0.0 0.0 5.9 0.7 0.1 14.8 1.3 0.8 0.6 8.4 1.2 0.2 0.0 27.8 4.1 0.3 0.3 0.1 0.3 0.2 0.2 1.7 0.3 1.7 5.4 2.3 0.2 1.7 0.9 3.0 1.1 0.8 1.5 1.0 2.1 4.4 0.2 0.4 1.2 3.2 0.0 0.0 7.9 0.0 5.9 5.3 12.0 0.8 7.9 14.8 10.9 5.8 6.1 7.3 8.9 7.0 6.7 6.8 0.5 12.0 10.7 8.3 6.8 8.9 11.9 12.0 3.7 12.4 9.7 8.6 10.2 6.7 9.7 7.7 35.7 17.3 20.1 9.8 9.3 6.6 4.8 35.7 12.0 14.8 24.4 2.0 16.9 11.6 16.2 0.4 26.9 14.2 0.0 17.8 5.0 32.5 16.5 8.1 50.0 15.1 4.8 6.4 36.8 29.9 0.4 28.1 17.9 28.7 13.6 10.0 15.8 12.5 7.0 23.7 8.4 1.3 19.4 16.4 0.2 1.1 8.0 8.8 13.1 5.6 7.8 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730196-150765957 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 171.4;lymphoid tissue: 111.4" "Cell type enhanced" "Detected in many" 13 "Hofbauer cells: 672.3;Kupffer cells: 1992.4;Macrophages: 1161.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 171.4;intermediate monocyte: 151.2;myeloid DC: 43.5;neutrophil: 94.5;non-classical monocyte: 138.5" "Group enriched" "Detected in all" 9 "dendritic cells: 43.5;granulocytes: 94.5;monocytes: 171.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 21.6;HMC-1: 51.4;U-698: 109.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 19000000 Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 41.6 9.3 6.8 32.3 10.3 30.3 9.7 1.9 6.2 4.7 32.9 6.6 5.6 19.6 3.7 12.9 8.8 10.7 15.9 17.3 6.4 5.1 9.6 21.5 55.8 99.5 12.6 2.3 7.6 6.4 0.4 3.4 14.4 9.3 7.5 33.4 6.5 12.9 3.3 3.5 3.8 38.0 6.8 17.1 111.4 13.8 3.8 9.5 12.9 7.6 4.6 22.8 21.5 5.3 11.1 43.5 94.5 171.4 3.3 5.6 145.4 1.0 3.3 0.0 0.0 0.4 0.3 0.3 0.0 3.3 0.2 0.6 0.0 21.6 14.9 1.6 0.1 6.1 0.4 0.0 0.1 0.0 8.3 0.0 6.5 0.1 0.0 0.0 8.9 51.4 0.6 0.0 1.9 0.1 0.1 1.2 0.0 0.6 13.0 0.4 0.0 0.0 6.3 0.0 0.0 0.0 3.7 1.2 18.2 4.0 3.2 0.0 0.1 0.2 0.9 0.3 0.0 0.0 18.2 1.8 1.3 0.2 0.0 0.3 9.0 0.8 109.3 7.6 9.6 0.8 1.2 171.4 16.5 3.2 151.2 3.9 11.1 3.9 3.8 43.5 10.2 3.9 3.6 94.5 3.3 138.5 9.4 5.6 145.4 6.8 10.3 1.9 6.2 6.4 5.1 12.6 2.3 9.3 9.5 101.3 167.2 252.8 20.8 15.0 2.0 3.0 84.1 518.0 134.2 40.1 11.8 3.1 0.0 145.4 5.3 35.1 277.5 0.0 157.6 3.9 26.3 16.7 100.8 19.5 672.3 0.0 40.9 64.4 1992.4 1.7 4.9 1161.7 54.0 251.5 198.9 0.3 150.7 378.7 2.1 4.2 4.1 19.4 7.6 0.2 0.4 13.6 5.1 117.4 149.8 109.8 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029679-97039643 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 154.7" "Cell type enhanced" "Detected in many" 12 "Cytotrophoblasts: 114.1;Extravillous trophoblasts: 136.0;Syncytiotrophoblasts: 56.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "NK-cell: 4.2;plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 42 "dendritic cells: 15.7;NK-cells: 4.2" "Group enriched" "Detected in many" 9 "BEWO: 92.0;SuSa: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 260000 "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.7 0.0 0.4 0.6 0.7 0.0 3.5 0.4 1.0 23.0 1.4 2.0 0.4 0.5 1.5 1.5 9.8 0.6 0.5 0.2 0.8 0.6 9.7 0.4 0.6 0.2 1.5 0.7 0.4 1.1 1.1 0.9 8.7 1.6 0.5 1.6 4.3 5.0 0.6 0.5 25.0 0.6 0.2 3.0 0.2 1.1 32.4 1.0 154.7 0.7 6.3 2.7 0.2 9.9 0.2 15.7 0.2 0.0 4.2 0.0 0.1 5.9 1.8 2.0 5.3 0.1 0.0 92.0 0.0 0.0 1.3 1.0 12.1 5.9 0.0 0.5 0.0 8.8 11.4 9.8 7.2 1.9 0.0 1.3 0.2 0.6 1.8 0.0 0.0 0.8 0.0 2.4 0.3 0.3 0.1 0.4 1.7 0.2 0.0 2.3 2.2 0.1 0.0 12.2 12.0 1.7 0.0 4.4 0.1 1.8 0.7 0.5 0.9 6.0 2.1 2.1 118.9 3.8 0.7 0.0 0.3 6.0 0.0 0.6 1.2 3.2 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.2 4.2 0.0 15.7 0.0 0.1 0.4 0.7 0.4 1.0 0.8 0.6 1.5 0.7 1.6 1.0 0.0 0.6 1.5 13.2 27.0 4.4 0.8 0.0 0.0 3.4 1.8 9.8 114.1 1.7 1.2 1.5 1.5 1.2 0.0 0.7 136.0 2.6 7.1 0.0 0.0 11.8 0.0 1.7 0.6 0.0 9.6 3.7 1.6 0.0 0.0 0.9 4.5 0.6 1.7 1.1 11.1 26.0 6.5 0.8 34.6 32.6 10.5 56.3 0.0 3.7 6.4 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58995185-59007247 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Hofbauer cells: 945.4;Macrophages: 462.5;monocytes: 1072.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.2;intermediate monocyte: 2.7;memory B-cell: 1.0;myeloid DC: 3.9;naive B-cell: 1.9;neutrophil: 3.5;non-classical monocyte: 2.9;plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 119.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 85000000 Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 70.7 27.9 12.4 40.8 20.4 20.7 51.2 14.6 13.5 25.4 52.8 16.0 19.9 40.8 20.6 25.5 20.1 20.7 22.3 50.1 9.8 13.3 34.9 83.7 54.3 61.2 18.8 10.5 29.7 29.0 30.6 27.6 38.6 19.2 28.8 37.8 31.5 40.3 17.7 20.7 12.9 63.6 26.4 22.1 56.5 19.2 13.8 14.9 18.4 42.4 17.5 35.8 29.8 21.5 1.9 3.9 3.5 3.2 0.3 0.6 0.8 27.6 21.5 0.0 0.0 25.4 29.2 15.2 45.5 50.4 34.9 31.2 41.5 46.5 15.2 30.2 119.6 0.0 22.1 13.7 43.1 23.9 48.6 1.8 13.9 34.8 0.0 26.6 1.6 48.4 24.8 26.0 15.2 18.2 11.6 55.2 0.0 10.0 7.7 23.3 0.0 0.1 15.0 1.7 12.1 21.5 0.3 0.1 18.2 25.5 6.5 0.4 0.3 35.4 41.0 0.1 14.2 18.9 23.6 60.6 0.0 23.6 30.7 0.2 36.7 22.3 2.9 0.4 33.5 0.0 0.0 3.2 0.3 0.6 2.7 0.0 1.0 0.4 0.1 3.9 1.9 0.4 0.1 3.5 0.3 2.9 2.2 0.2 0.8 12.4 20.4 14.6 13.5 9.8 13.3 18.8 10.5 19.2 14.9 14.9 4.0 130.0 51.2 44.8 4.6 17.5 53.5 8.1 5.7 68.0 0.0 34.5 19.9 168.0 2.8 62.8 285.7 23.3 37.2 91.0 58.0 41.9 10.4 307.7 945.4 11.1 26.0 44.2 260.7 3.3 12.0 462.5 96.2 1072.2 50.0 45.9 72.3 98.2 13.1 68.2 4.9 45.3 59.0 1.7 4.5 36.3 34.6 29.9 76.8 46.2 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: AB_2681013" "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.3 2.9 3.4 3.8 5.4 7.8 3.1 13.8 20.2 14.4 8.5 2.4 4.4 10.7 5.0 13.5 15.7 3.6 4.0 8.4 21.5 47.2 6.1 5.3 5.2 2.0 10.7 5.3 25.3 8.5 6.8 17.4 18.2 13.7 5.8 7.6 2.2 9.4 20.1 1.4 5.2 7.7 3.6 2.9 4.9 4.7 6.9 10.3 4.7 3.2 4.4 3.3 11.7 4.0 3.4 5.4 4.0 6.7 6.5 24.7 5.6 8.6 5.6 24.8 23.5 12.0 18.1 6.0 5.2 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 41.7 25.6 39.6 48.8 106.7 75.4 32.7 25.5 12.0 19.4 17.4 88.4 5.4 5.0 18.3 32.8 37.9 13.4 46.7 16.5 3.8 37.2 52.3 78.5 22.1 19.0 63.5 29.9 21.5 32.3 24.7 23.6 47.1 70.9 34.3 10.3 22.6 15.2 18.7 19.8 10.3 49.3 6.5 34.4 52.6 13.8 135.9 3.4 73.4 12.0 56.3 DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113020970 "Enzymes, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 52.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" NA NA "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: AB_731858, HPA057676: AB_2683500" "unprognostic (2.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-3)" "prognostic unfavorable (4.84e-4)" "unprognostic (1.87e-1)" "unprognostic (3.64e-2)" "unprognostic (6.26e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-2)" "prognostic unfavorable (2.66e-5)" "unprognostic (8.39e-2)" "unprognostic (2.84e-1)" "unprognostic (3.25e-2)" "unprognostic (5.75e-2)" 8.0 7.5 8.1 16.3 9.5 22.9 15.0 16.8 10.9 9.1 6.6 6.4 6.6 6.3 10.5 6.8 7.4 8.0 6.5 6.1 8.1 8.9 8.1 8.1 13.2 19.8 6.9 6.1 12.8 6.2 7.0 12.2 40.2 8.3 8.1 7.3 6.5 9.6 8.6 8.3 9.8 8.7 7.3 7.4 19.9 6.7 6.8 6.5 52.9 7.0 4.1 20.0 8.7 9.1 5.1 6.5 16.3 8.3 3.9 5.9 3.2 3.6 3.1 14.1 11.3 2.8 3.1 22.8 3.3 2.7 4.2 6.1 14.6 7.8 19.1 5.3 1.9 3.4 4.5 16.2 4.5 5.1 5.1 7.0 17.9 2.7 5.8 3.2 10.9 9.3 2.9 3.1 5.1 5.1 4.0 7.1 14.7 13.2 7.5 3.8 4.6 16.0 11.6 12.2 2.2 1.9 15.7 13.4 7.1 6.5 9.3 3.3 7.0 4.6 5.2 6.7 15.3 15.4 14.6 4.6 4.7 8.4 2.4 5.0 5.1 11.2 14.6 2.7 15.3 3.6 12.2 7.2 5.5 4.0 7.1 5.5 5.1 4.9 4.2 6.5 3.6 4.6 4.7 16.3 3.9 8.3 3.5 5.9 3.2 8.1 9.5 16.8 10.9 8.1 8.9 6.9 6.1 8.3 6.5 17.9 15.6 38.9 16.7 24.6 21.6 11.4 5.1 18.7 22.7 19.2 74.6 53.4 16.6 8.9 23.5 21.8 10.0 0.0 10.3 41.1 27.2 25.6 18.5 5.9 27.7 27.0 15.5 27.6 71.2 42.2 17.5 46.5 25.3 36.9 9.1 34.4 12.8 10.5 10.3 11.2 35.2 6.5 17.9 29.3 19.0 23.2 53.9 38.8 11.3 37.6 DCPS "HINT-5, HSL1, HSPC015" ENSG00000110063 "Decapping enzyme, scavenger" Q96C86 11 126303752-126345749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Hydrolase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039632, HPA058597" Supported Supported Nucleoplasm,Cytosol NA NA 1400000 Nucleoplasm Cytosol "HPA039632: AB_10794200, HPA058597: AB_2683770" "unprognostic (1.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.55e-2)" "unprognostic (5.22e-2)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (5.57e-2)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "unprognostic (5.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.24e-2)" "unprognostic (8.04e-2)" "unprognostic (7.67e-2)" "unprognostic (3.40e-2)" 11.1 13.1 6.8 14.4 8.2 13.5 9.2 8.5 14.5 12.1 10.6 6.8 8.0 7.8 12.4 9.6 14.4 9.9 13.9 10.9 5.5 6.1 13.3 39.6 9.9 18.5 6.3 5.8 11.8 17.2 7.0 9.5 14.1 6.8 12.7 11.7 13.3 17.4 9.4 21.8 11.3 9.7 11.3 7.1 21.9 9.6 13.4 6.5 22.0 12.7 18.5 22.1 15.1 9.8 13.2 39.5 3.2 14.3 7.8 14.6 7.1 9.5 6.0 7.5 12.4 5.8 7.8 6.3 5.1 7.5 7.8 7.9 11.3 19.7 13.0 19.2 8.1 5.1 11.2 10.6 16.0 5.2 24.7 5.7 19.1 6.8 9.8 12.6 20.5 17.3 7.9 10.1 9.9 13.5 3.9 10.4 10.9 7.7 22.4 8.5 13.8 13.0 23.5 5.2 51.3 20.6 9.1 11.0 24.8 7.5 10.7 9.7 7.4 15.4 12.6 9.3 4.7 21.4 12.8 6.6 12.2 5.7 5.8 9.5 9.0 8.3 13.5 3.5 35.5 30.7 1.7 9.2 3.2 8.8 14.3 8.2 13.2 8.5 9.0 15.4 9.0 6.0 6.8 0.5 7.8 12.6 39.5 14.6 7.1 6.8 8.2 8.5 14.5 5.5 6.1 6.3 5.8 6.8 6.5 11.9 12.8 34.4 16.6 6.2 6.5 4.5 53.5 16.0 5.7 40.1 0.0 37.0 48.0 17.0 5.4 8.7 5.2 0.0 25.4 38.8 12.7 9.2 16.2 22.8 26.1 3.2 7.0 7.4 13.7 1.7 15.8 10.4 16.9 14.4 9.7 7.8 16.6 14.0 17.3 10.8 7.1 19.4 11.3 11.2 28.0 7.9 22.7 27.7 13.4 19.7 DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol NA NA 13000 "Nucleoplasm, Cytosol" "HPA035894: AB_10673488" "unprognostic (1.26e-1)" "unprognostic (9.80e-3)" "unprognostic (3.15e-2)" "unprognostic (3.78e-3)" "unprognostic (3.13e-3)" "unprognostic (2.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.59e-3)" "unprognostic (2.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "prognostic favorable (1.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" 24.8 46.2 24.7 19.9 23.8 12.9 27.3 11.6 28.3 27.1 20.4 17.3 22.6 16.4 26.0 20.1 30.9 25.9 40.9 25.8 22.5 22.2 25.7 47.6 25.8 29.4 21.1 20.3 35.9 51.7 28.3 25.3 18.9 21.3 23.7 21.5 30.0 26.4 22.8 24.8 19.4 19.1 27.4 25.6 24.9 27.2 11.8 16.7 15.0 52.9 21.3 26.0 24.5 25.1 31.9 24.8 23.7 25.7 30.8 36.8 22.7 22.7 21.0 21.4 19.8 32.4 44.3 28.1 43.9 39.2 31.5 19.5 21.3 44.2 7.9 10.9 42.7 21.5 11.3 15.6 27.4 29.0 38.3 11.8 36.5 12.2 25.3 34.8 35.5 22.9 36.8 29.2 27.6 28.8 31.9 26.9 17.5 36.2 79.2 41.8 16.6 23.0 21.7 17.0 9.2 18.3 25.1 15.3 15.3 25.4 27.3 21.2 13.1 20.7 17.9 20.5 20.8 13.7 18.6 31.3 26.2 20.2 12.6 33.4 30.4 16.4 10.1 28.9 23.3 30.8 23.7 22.0 19.7 29.2 25.7 36.8 31.9 25.6 29.7 24.8 21.7 25.5 26.7 1.6 30.8 24.9 19.1 21.9 22.7 24.7 23.8 11.6 28.3 22.5 22.2 21.1 20.3 21.3 16.7 11.9 15.0 31.7 28.8 22.6 4.3 20.6 38.2 18.7 11.4 31.4 3.9 16.6 31.5 61.9 6.3 32.1 15.5 23.3 47.4 19.9 41.7 29.4 22.0 38.0 48.4 3.2 13.9 25.2 29.6 13.2 40.9 29.6 25.3 38.7 28.6 31.5 60.2 10.5 33.2 34.1 6.3 32.3 28.2 9.3 15.4 20.1 6.1 27.4 29.9 34.5 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423619-30430075 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Approved Nucleoplasm,Cytosol NA Yes 270000 "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavorable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favorable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 15.3 15.8 14.8 25.0 13.2 12.5 20.7 15.5 19.2 12.1 37.4 10.3 11.3 20.7 14.1 14.4 19.7 18.9 28.1 23.3 12.1 12.6 27.0 25.3 11.2 27.6 13.3 16.6 16.6 25.2 16.4 7.7 16.3 11.4 15.4 40.3 10.6 20.5 21.1 28.3 16.1 22.9 13.9 11.3 22.5 16.4 9.9 7.8 21.3 22.6 26.0 25.0 13.2 13.0 47.3 30.9 19.0 24.5 23.1 26.2 25.3 26.6 32.7 14.9 19.2 4.2 5.7 13.8 12.8 7.7 19.4 19.8 24.6 22.8 36.1 27.0 8.0 12.4 21.0 30.9 25.1 24.3 19.0 48.8 21.0 15.0 32.0 5.5 37.5 32.8 6.6 14.3 21.6 12.5 5.9 19.9 19.4 26.4 12.7 13.7 46.5 44.5 42.1 19.7 27.0 26.4 63.2 16.6 47.0 22.4 17.3 31.8 18.0 8.5 30.5 12.0 10.2 26.3 16.1 10.0 15.0 13.4 19.3 23.0 8.4 25.0 46.0 9.9 31.2 17.5 19.0 12.4 11.7 18.8 22.1 26.2 47.3 24.2 21.3 28.7 40.2 21.8 21.0 1.5 23.1 24.5 30.9 24.1 25.3 14.8 13.2 15.5 19.2 12.1 12.6 13.3 16.6 11.4 7.8 17.9 14.6 32.0 37.1 80.1 23.9 33.1 61.1 20.1 19.4 41.8 7.9 81.7 107.8 107.5 10.2 47.2 79.9 0.0 108.6 68.9 31.5 41.3 31.1 18.1 68.6 14.3 37.0 25.2 16.6 36.0 18.1 35.6 45.5 108.2 103.3 19.7 78.9 105.2 18.7 54.0 16.3 19.4 35.0 2.8 33.6 70.1 23.2 25.9 124.8 43.2 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.6" "Cell type enhanced" "Detected in many" 8 "Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cell line enhanced" "Detected in many" "OE19: 36.9;SH-SY5Y: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006308, HPA071064" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 140000 "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532, HPA071064: " "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favorable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favorable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 4.3 14.3 43.9 5.8 44.9 0.7 6.6 14.4 37.2 7.7 22.1 20.7 4.3 21.1 6.0 33.8 4.9 18.4 12.2 6.4 29.5 24.1 61.6 39.9 11.8 1.1 24.9 37.0 3.4 13.8 13.0 7.2 3.1 13.8 13.1 21.4 4.1 8.5 6.2 13.8 2.8 19.9 7.4 8.1 4.1 15.6 9.3 11.0 0.0 14.1 1.0 1.2 6.0 3.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 18.3 2.3 6.5 1.2 10.9 9.2 0.8 21.7 13.2 7.7 8.2 26.1 4.9 0.0 9.1 24.6 7.6 5.3 23.5 4.5 9.9 0.0 9.0 0.0 6.2 9.1 3.9 16.7 1.0 7.7 0.4 6.5 4.1 9.8 12.3 0.0 0.0 1.8 19.8 1.5 0.8 0.0 7.8 36.9 6.8 0.0 15.2 0.2 33.0 13.7 18.3 35.6 2.8 16.5 2.6 9.7 8.9 1.2 24.0 6.8 5.5 1.6 15.1 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 43.9 44.9 14.4 37.2 29.5 24.1 24.9 37.0 13.8 11.0 32.8 31.3 4.2 4.0 12.2 2.7 11.4 68.8 30.8 13.6 66.3 3.9 1.7 106.1 15.6 17.1 4.5 78.7 0.0 26.7 0.8 23.5 37.8 0.0 94.3 0.9 0.0 32.8 9.2 2.2 18.4 14.7 1.5 11.8 1.0 77.8 59.7 34.2 73.6 70.4 219.6 8.0 12.9 18.9 5.0 5.6 12.5 0.7 3.3 85.4 6.5 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 10.7;ASC TERT1: 13.4;EFO-21: 17.1;fHDF/TERT166: 10.6;SK-MEL-30: 10.7;U-2 OS: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1800000 Mitochondria "HPA012389: , HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 24.3 7.8 12.5 11.1 10.3 5.5 22.7 3.1 7.8 32.1 17.0 7.9 12.9 2.6 34.6 22.0 18.4 18.1 26.7 20.7 11.8 10.8 16.9 12.9 37.4 16.5 10.6 6.6 22.5 4.3 3.0 6.2 13.7 13.1 19.8 5.4 13.0 18.1 13.2 6.8 15.1 22.3 27.1 18.9 21.4 11.4 7.3 9.9 14.1 35.4 17.1 8.9 16.3 23.4 2.9 5.5 8.0 2.7 2.3 0.5 0.3 0.4 6.6 0.2 1.4 10.7 13.4 0.7 0.6 0.3 0.4 0.1 4.4 0.7 0.2 17.1 10.6 0.0 0.8 0.0 6.2 0.0 0.1 9.0 0.5 0.5 0.1 0.3 0.9 0.0 8.6 0.1 0.8 0.1 0.7 0.1 9.7 0.2 2.3 0.0 3.6 0.5 2.5 0.1 1.4 0.2 0.3 0.5 0.0 7.6 0.7 0.4 1.0 0.3 0.0 10.7 0.7 0.7 0.9 1.2 0.8 12.7 0.2 0.1 2.7 9.3 2.5 7.4 1.5 0.2 8.0 0.8 7.7 0.5 2.6 0.3 2.9 0.2 0.3 1.5 2.5 0.1 0.1 1.3 2.3 2.7 5.5 0.4 0.3 12.5 10.3 3.1 7.8 11.8 10.8 10.6 6.6 13.1 9.9 26.8 17.1 39.8 83.5 59.4 4.0 32.5 38.2 33.5 17.0 78.5 27.5 13.7 150.9 113.3 87.7 94.4 114.4 0.0 28.5 24.3 96.9 77.4 109.8 27.2 186.9 0.0 143.9 57.7 101.8 14.7 167.1 97.2 97.8 79.4 47.6 79.4 71.2 98.2 143.9 116.9 22.9 103.5 127.7 2.6 12.4 51.8 15.1 33.1 63.1 53.8 DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15631111 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Cardiomyocytes: 352.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Supported Nucleoplasm,Cytosol NA NA 46000 Nucleoplasm Cytosol "CAB012280: , HPA034502: AB_10794321, HPA034503: AB_10795025" "unprognostic (9.94e-2)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (8.36e-3)" "unprognostic (9.28e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (2.55e-1)" "unprognostic (2.05e-1)" "unprognostic (4.81e-3)" "unprognostic (3.89e-2)" "unprognostic (2.03e-1)" "prognostic favorable (9.69e-4)" "unprognostic (3.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.94e-2)" "unprognostic (1.20e-3)" 23.8 28.2 29.3 17.6 35.0 17.1 30.1 35.3 37.2 25.1 24.5 15.0 20.5 21.0 24.3 25.6 27.7 21.0 15.8 47.6 34.7 25.3 35.8 35.2 17.8 16.0 24.5 36.9 23.6 27.6 42.1 41.2 28.1 35.1 22.2 28.1 14.8 23.9 24.5 67.5 24.5 25.9 31.0 21.0 17.1 24.1 19.2 23.0 23.0 29.6 24.8 21.5 26.1 19.8 18.7 22.8 19.2 25.1 23.0 26.6 19.9 19.3 29.7 42.2 31.5 36.7 32.2 48.7 40.7 34.2 40.1 33.8 47.4 20.0 50.3 19.8 46.9 29.6 29.5 57.7 39.1 42.5 21.4 37.5 55.1 39.7 59.7 27.6 45.0 25.9 25.0 26.9 33.4 32.1 25.4 36.1 23.8 56.0 16.6 39.5 27.1 24.6 34.0 54.3 48.9 25.1 29.7 63.9 36.4 45.9 39.0 34.1 42.6 27.8 29.4 37.0 31.6 20.4 19.1 29.1 33.7 34.8 21.1 45.9 21.7 37.7 67.9 30.3 36.1 31.3 19.2 20.0 11.5 20.2 25.1 21.3 18.7 23.4 23.4 22.8 18.0 26.6 23.6 3.1 23.0 23.2 19.5 21.6 19.9 29.3 35.0 35.3 37.2 34.7 25.3 24.5 36.9 35.1 23.0 74.5 45.2 27.6 50.5 35.7 56.6 352.9 63.7 95.0 68.2 85.5 49.1 96.2 121.0 87.1 11.9 56.2 48.4 23.3 104.7 96.0 66.4 31.2 54.4 106.7 46.5 42.9 50.1 40.5 25.3 12.7 67.3 39.1 47.2 31.5 56.7 55.3 88.0 59.6 73.6 95.2 67.2 58.2 49.9 167.4 57.2 36.9 67.1 26.6 62.9 32.7 DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665025-108940930 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli NA NA Nucleoli "HPA004691: AB_1078629" "unprognostic (9.49e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (7.97e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (2.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.00e-1)" "prognostic favorable (2.14e-5)" "unprognostic (5.20e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-1)" "unprognostic (2.43e-3)" 14.0 11.9 17.3 15.0 20.3 10.4 15.5 20.5 18.3 14.3 12.2 8.1 11.7 8.8 18.4 12.8 12.6 16.8 8.8 12.1 13.5 11.5 19.6 12.5 10.6 13.1 12.2 16.3 18.6 18.0 16.7 22.2 12.9 13.1 12.4 13.3 7.9 10.6 14.7 13.6 14.8 9.1 16.8 13.3 15.0 11.3 25.1 12.6 13.8 13.4 8.8 14.2 14.3 18.8 11.6 8.4 1.4 6.7 9.4 11.3 4.3 7.4 7.3 6.9 9.7 6.9 5.6 7.2 8.0 4.3 9.7 9.6 20.8 10.9 25.3 15.1 6.1 10.5 8.3 19.8 9.7 14.0 9.6 8.9 17.1 4.3 7.7 12.3 17.4 8.2 5.0 7.6 11.0 13.8 5.8 8.8 6.6 24.0 2.8 9.5 4.8 14.6 14.7 9.0 14.0 11.1 12.5 11.3 23.6 6.0 6.4 12.9 6.8 11.2 9.9 4.2 9.7 12.0 6.1 9.2 10.2 10.4 9.7 10.8 4.3 7.5 58.4 3.5 21.1 10.3 1.4 5.0 1.0 8.6 6.7 11.3 10.4 7.5 10.1 8.4 11.6 8.1 7.8 0.7 9.4 6.4 8.2 6.3 4.3 17.3 20.3 20.5 18.3 13.5 11.5 12.2 16.3 13.1 12.6 14.9 30.3 22.6 17.3 25.2 21.1 18.2 7.6 18.7 22.7 3.5 90.3 21.4 16.6 13.2 28.6 19.8 2.9 0.0 18.3 17.8 17.6 12.7 13.9 10.2 13.1 17.5 14.5 9.2 9.2 5.9 27.3 18.2 6.8 18.0 7.8 8.9 15.1 3.5 20.1 46.2 25.2 12.9 15.6 64.4 44.6 25.3 21.6 14.4 13.6 12.2 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073845-31104791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Rod photoreceptor cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA065197 Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome" No Yes Nucleoplasm "Nucleoli fibrillar center, Centrosome" "HPA065197: AB_2685430" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 6.3 5.3 6.4 8.0 8.7 21.0 5.9 18.1 10.5 7.6 6.1 6.0 8.8 7.1 11.0 3.7 7.6 7.5 5.1 4.0 7.0 2.7 6.5 7.0 4.9 14.9 8.4 4.6 9.6 19.0 7.7 9.3 5.6 7.1 8.0 8.6 5.0 11.3 7.1 8.8 14.2 12.1 8.0 6.7 10.9 8.0 8.2 9.4 33.2 7.2 6.4 11.1 5.8 7.8 5.8 4.9 1.3 7.3 4.3 5.5 1.9 12.5 12.2 14.2 12.7 2.2 4.8 20.9 7.8 3.9 9.1 9.8 14.5 21.4 16.4 10.9 4.1 8.5 12.4 11.2 10.7 7.3 15.0 23.0 19.5 20.3 8.9 0.8 13.7 12.7 4.5 4.8 11.6 9.1 5.9 4.4 19.7 9.5 36.8 6.5 10.4 23.5 20.5 29.9 15.3 6.6 18.9 22.2 22.8 4.8 14.3 10.2 7.5 8.0 12.3 3.9 24.8 10.4 8.7 3.6 8.0 15.7 15.4 14.1 14.9 11.5 39.2 9.4 11.0 7.2 0.0 2.3 1.3 4.2 2.5 3.3 5.2 4.0 3.1 3.1 5.8 4.1 5.5 1.1 4.3 7.3 4.9 3.4 1.9 6.4 8.7 18.1 10.5 7.0 2.7 8.4 4.6 7.1 9.4 3.0 7.4 12.7 4.5 5.4 7.7 2.2 5.1 6.7 5.7 0.0 13.7 5.2 0.0 2.2 1.3 3.0 4.0 0.0 2.9 5.8 4.3 5.0 5.7 6.6 4.3 7.9 0.0 6.2 4.6 0.9 6.6 4.6 6.8 5.4 5.0 2.3 2.5 2.9 4.2 1.1 25.5 0.0 3.5 3.2 17.6 5.6 2.2 6.9 7.4 4.1 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483440-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" NA NA 90000 "Nuclear speckles" "CAB024908: , HPA063142: AB_2684949" "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 49.7 43.1 46.3 49.2 54.5 19.8 50.8 69.7 52.0 47.7 53.3 56.5 54.4 33.1 58.5 82.9 37.5 52.2 46.1 39.9 47.0 31.2 34.3 41.9 41.5 52.6 64.0 37.7 67.8 41.5 68.5 83.7 49.4 46.0 46.2 36.8 51.4 43.9 51.8 89.2 60.3 38.7 52.7 47.1 54.1 39.7 24.6 63.1 69.3 59.8 29.2 47.7 54.5 52.9 10.3 12.4 23.7 9.5 4.0 9.9 6.1 29.7 28.9 59.0 35.4 39.1 45.1 30.8 25.4 25.4 37.1 36.1 27.6 24.9 57.8 17.5 33.2 23.6 33.0 64.5 36.0 41.5 56.9 36.8 35.9 48.4 33.0 42.0 45.8 42.8 31.4 47.3 24.2 41.8 53.1 42.3 27.9 37.1 65.5 29.4 19.4 32.2 39.1 38.0 43.3 14.1 58.5 32.9 35.4 35.3 39.8 34.1 20.1 39.8 31.5 42.0 47.3 27.2 35.5 34.3 31.7 19.8 20.2 19.1 50.6 35.0 49.8 41.0 29.7 39.0 8.5 9.5 11.0 9.9 7.3 9.4 9.0 8.0 7.1 6.8 10.3 5.8 7.5 23.7 4.0 6.8 12.4 7.9 6.1 46.3 54.5 69.7 52.0 47.0 31.2 64.0 37.7 46.0 63.1 199.5 293.3 141.2 174.3 198.5 453.4 121.4 180.9 248.9 260.5 268.7 331.8 105.4 28.2 86.0 34.1 224.8 142.5 23.3 77.8 81.8 163.6 205.3 193.1 180.6 98.1 303.5 226.7 240.6 191.5 27.7 299.7 152.5 146.8 97.4 162.3 302.5 92.9 133.3 262.0 57.6 548.6 284.6 173.1 96.3 66.0 244.7 116.6 128.3 119.9 237.1 DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814650-117832379 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 90.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA035400: AB_10672091, HPA041056: AB_2677277" "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (2.06e-1)" "unprognostic (1.77e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (8.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (7.28e-2)" "unprognostic (5.65e-2)" 35.3 21.3 20.5 28.7 26.0 17.4 31.2 27.1 25.6 31.2 27.9 16.7 21.6 20.9 32.0 22.9 27.8 28.5 21.3 22.9 19.6 19.1 32.0 40.3 24.1 35.0 25.5 22.9 36.3 29.5 21.0 25.9 25.0 25.0 25.0 30.3 11.5 24.2 26.6 37.0 24.9 26.3 28.3 30.8 46.5 26.2 22.9 31.1 40.7 31.3 23.9 37.6 37.6 23.7 22.2 20.5 9.4 18.5 17.2 23.6 16.3 22.0 10.0 15.0 13.5 8.9 8.0 24.8 13.1 10.4 18.1 16.0 24.6 14.6 32.5 21.5 10.8 16.8 17.1 29.0 16.9 26.8 16.5 20.3 31.0 9.4 24.7 12.4 41.4 16.2 8.3 15.7 23.0 23.3 9.2 10.8 16.9 33.8 14.1 13.8 13.7 22.6 21.6 37.6 18.7 15.2 19.7 23.4 28.4 12.0 13.1 14.4 24.5 15.2 16.8 17.0 15.9 10.6 22.9 8.3 16.2 23.9 11.4 23.5 16.3 20.2 90.0 11.9 19.6 7.2 6.2 13.8 9.4 16.2 17.3 20.6 22.2 19.3 18.5 12.5 19.1 23.6 20.7 3.6 17.2 18.5 20.5 15.0 16.3 20.5 26.0 27.1 25.6 19.6 19.1 25.5 22.9 25.0 31.1 89.3 53.4 123.6 65.7 171.3 131.1 44.8 122.3 89.7 94.4 115.1 78.5 95.4 99.5 87.4 10.8 105.7 49.3 23.3 99.4 101.8 89.3 52.4 108.5 162.0 78.1 77.9 54.6 103.7 79.2 10.1 98.7 99.7 87.7 93.8 85.3 76.8 106.8 59.6 97.6 93.5 118.7 64.7 108.2 111.4 127.7 140.4 74.3 107.1 93.0 50.8 DDX19A "DDX19L, FLJ11126" ENSG00000168872 "DEAD-box helicase 19A" Q9NUU7 16 70346829-70373383 "Enzymes, Predicted intracellular proteins, Transporters" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045252, HPA066668" Approved Uncertain Nucleoplasm NA NA Nucleoplasm "HPA045252: AB_10961128, HPA066668: " "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (9.07e-2)" "unprognostic (3.95e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (2.38e-4)" "prognostic unfavorable (8.05e-5)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (1.67e-1)" "unprognostic (1.30e-1)" "unprognostic (5.87e-2)" "unprognostic (1.24e-1)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (3.01e-2)" "unprognostic (6.68e-3)" 18.4 20.6 14.5 15.5 19.7 9.8 18.1 16.6 19.6 16.9 19.2 19.2 17.8 9.3 22.0 14.2 19.2 17.1 16.1 22.1 18.6 13.5 16.6 24.8 14.4 18.0 17.1 15.5 21.6 22.5 31.7 17.4 21.8 15.1 15.4 14.4 14.2 14.4 21.1 51.5 15.8 13.5 25.9 15.4 14.1 17.2 9.7 13.7 17.1 19.7 14.4 18.4 19.5 15.5 8.1 14.2 7.9 11.4 8.2 10.3 8.8 13.2 15.0 15.8 16.0 23.8 16.2 15.1 16.9 17.4 26.8 20.9 22.5 9.9 22.2 16.1 17.8 12.7 15.2 28.3 16.8 22.2 7.4 15.4 11.6 12.3 27.6 21.5 20.2 9.7 19.9 12.1 24.4 19.2 13.2 17.0 16.2 27.9 5.8 16.0 19.0 22.4 16.8 25.5 15.8 9.2 27.8 10.6 30.4 16.2 8.2 13.0 17.5 43.3 9.5 12.7 17.1 17.4 12.9 11.5 18.7 14.8 11.8 16.0 16.4 24.6 48.9 12.6 18.5 18.3 7.9 11.4 5.8 10.2 10.7 9.4 7.7 8.9 10.0 14.2 8.1 9.9 10.3 0.7 8.2 9.6 7.3 7.5 8.8 14.5 19.7 16.6 19.6 18.6 13.5 17.1 15.5 15.1 13.7 14.9 20.2 21.7 15.7 8.9 31.9 16.2 28.1 13.4 22.7 10.4 31.4 18.9 8.3 11.1 1.4 13.8 6.6 23.3 12.1 13.1 12.8 16.7 17.3 15.3 12.3 22.3 13.8 14.7 14.5 1.3 24.2 11.8 10.1 17.2 8.8 18.0 11.6 8.6 11.7 10.6 31.0 25.8 15.5 12.2 16.4 8.9 14.4 12.9 11.3 15.9 DDX19B "DBP5, DDX19" ENSG00000157349 "DEAD-box helicase 19B" Q9UMR2 16 70289663-70335283 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 170.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037229, CAB037284, HPA046380, HPA066668" Approved Uncertain Nucleoplasm NA NA Nucleoplasm "CAB037229: AB_1840791, CAB037284: AB_1840792, HPA046380: AB_2679645, HPA066668: " "unprognostic (2.91e-2)" "unprognostic (5.37e-2)" "unprognostic (6.48e-2)" "unprognostic (3.55e-2)" "unprognostic (3.98e-2)" "unprognostic (4.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.98e-2)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (4.07e-1)" "unprognostic (7.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-1)" "unprognostic (1.04e-1)" "unprognostic (6.32e-2)" 22.2 18.6 8.8 16.6 12.7 19.4 20.1 30.4 16.3 13.1 16.7 14.6 13.8 14.4 15.0 13.9 16.0 13.2 15.2 15.0 8.3 8.3 15.9 33.9 16.6 15.3 10.5 10.7 14.6 21.6 20.3 17.9 12.0 13.2 13.8 18.2 19.3 16.8 15.2 24.8 26.9 16.6 15.7 10.1 17.8 18.5 64.3 12.3 17.4 18.0 16.9 20.8 16.2 13.9 21.1 21.1 27.0 28.6 22.1 35.4 22.5 2.0 12.4 17.7 16.0 9.8 13.1 15.3 10.0 14.2 22.0 23.0 26.4 15.3 16.2 9.5 12.6 8.9 12.2 0.1 5.7 22.8 6.7 11.3 9.6 8.1 21.6 21.1 20.5 9.3 16.1 11.3 16.7 12.7 9.1 16.8 5.0 9.7 7.0 13.4 14.2 0.0 29.7 11.1 7.7 5.2 28.4 9.6 23.4 13.1 11.5 11.6 15.3 23.6 5.4 12.7 8.1 12.1 18.2 10.2 10.4 9.3 8.6 9.2 15.1 7.8 37.7 3.4 16.8 13.4 27.0 22.1 19.0 23.2 28.6 22.3 21.1 20.9 25.3 21.1 19.0 19.0 18.0 4.1 22.1 17.7 6.5 35.4 22.5 8.8 12.7 30.4 16.3 8.3 8.3 10.5 10.7 13.2 12.3 11.9 17.9 27.3 15.3 8.4 17.8 6.6 12.7 29.4 20.5 10.4 11.8 16.5 26.6 35.6 170.5 17.5 27.5 0.0 57.8 18.6 16.1 14.9 10.5 12.4 25.9 9.5 21.1 11.6 14.6 32.4 19.2 19.7 3.3 43.3 14.6 16.0 37.9 34.5 14.9 17.4 15.7 12.9 12.3 78.8 7.4 9.2 26.4 25.5 20.3 15.7 DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111755245-111768016 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 81.7" "Group enriched" "Detected in many" 13 "Early spermatids: 570.4;Late spermatids: 538.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" NA NA "Nucleoplasm, Nuclear bodies" Cytosol "CAB015427: AB_629518, HPA005516: AB_1849612" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "prognostic favorable (9.85e-5)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (6.35e-6)" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (7.46e-3)" "unprognostic (4.21e-1)" "unprognostic (5.22e-2)" "unprognostic (1.05e-3)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (1.30e-2)" 3.1 2.8 2.9 2.7 4.3 5.9 9.8 5.8 5.1 2.7 2.6 1.8 2.6 2.0 4.0 2.9 2.6 3.7 1.7 2.0 4.3 1.6 2.7 2.4 4.1 3.8 2.4 1.9 3.9 2.9 4.0 3.9 2.7 3.4 2.9 2.6 1.2 2.6 2.7 5.1 2.5 3.5 2.9 5.6 4.5 2.8 81.7 3.3 5.1 3.2 1.7 4.1 2.9 5.0 11.9 7.4 12.7 7.4 10.5 14.1 7.8 11.4 4.7 12.2 11.0 8.8 7.0 11.4 11.2 8.7 16.1 15.7 7.0 4.0 26.8 8.8 7.6 5.7 9.2 14.4 11.3 18.0 12.2 13.0 13.0 9.2 7.2 8.8 12.8 9.6 7.0 9.9 13.7 13.9 4.5 11.1 10.5 12.4 9.8 12.2 10.8 15.7 13.0 15.3 6.9 9.6 15.4 20.1 6.7 10.5 9.0 12.7 11.5 10.8 13.5 18.0 10.6 8.4 13.6 9.8 9.8 14.5 17.5 13.0 4.9 6.9 20.5 10.2 13.2 22.1 12.7 7.0 6.9 10.0 7.3 13.3 11.9 11.7 11.8 7.4 10.1 14.1 12.3 5.0 10.5 7.4 5.2 11.7 7.8 2.9 4.3 5.8 5.1 4.3 1.6 2.4 1.9 3.4 3.3 11.9 6.5 3.7 7.8 9.6 12.2 5.9 2.5 13.4 12.5 5.2 2.0 8.6 3.3 8.9 570.4 7.1 2.4 0.0 6.0 6.8 4.8 3.0 7.0 4.9 8.0 6.4 4.1 3.7 9.1 538.8 15.3 8.7 1.7 3.6 5.7 6.3 6.3 2.9 12.4 6.9 8.9 6.5 10.3 41.2 25.6 6.4 4.2 7.0 5.8 5.5 DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956128-68985073 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Suprabasal keratinocytes: 515.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 14000 "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA036592: AB_10673625, HPA036593: AB_2675208" "unprognostic (3.04e-1)" "unprognostic (6.81e-3)" "unprognostic (1.13e-2)" "unprognostic (1.21e-2)" "unprognostic (1.75e-2)" "unprognostic (6.71e-3)" "unprognostic (1.34e-2)" "unprognostic (1.99e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (3.12e-4)" "unprognostic (1.64e-1)" "unprognostic (1.39e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-2)" "unprognostic (1.24e-2)" "unprognostic (5.74e-3)" 37.5 16.0 10.0 26.6 13.3 46.8 24.4 8.0 11.8 18.5 20.1 7.2 16.2 13.3 18.7 13.7 28.3 20.1 17.6 19.1 11.4 8.0 25.1 48.0 25.9 24.4 14.9 7.2 30.2 27.9 15.6 20.7 22.8 18.3 14.0 17.6 5.9 18.0 17.8 61.2 22.5 18.5 19.0 20.4 43.5 19.0 12.9 13.3 27.1 18.1 24.1 25.8 33.2 22.4 12.6 11.5 17.1 17.3 7.7 15.0 6.2 33.1 19.7 11.5 35.6 10.4 13.8 24.4 22.8 18.4 29.5 25.1 63.7 22.8 50.0 14.1 18.9 13.9 29.6 44.3 28.4 39.6 15.5 31.2 35.0 14.0 26.4 22.3 83.2 33.3 14.1 37.0 35.2 59.0 13.7 21.4 18.8 66.6 25.0 20.7 15.1 32.6 18.1 31.5 15.8 42.1 29.2 18.9 24.6 19.6 17.9 23.9 25.6 20.5 45.5 26.6 14.5 25.8 17.5 22.0 17.3 24.6 23.2 40.0 28.9 38.2 73.9 14.4 63.2 11.7 5.0 9.7 17.1 8.4 15.0 15.0 12.6 10.9 11.0 11.5 10.4 10.3 11.3 4.5 7.7 17.3 10.8 7.9 6.2 10.0 13.3 8.0 11.8 11.4 8.0 14.9 7.2 18.3 13.3 95.3 139.8 208.1 223.1 488.7 27.0 59.4 112.1 83.0 195.7 68.0 39.3 72.5 61.3 111.8 41.5 139.6 52.0 23.3 160.6 118.9 142.8 222.8 164.0 182.5 102.7 23.8 83.2 113.5 149.3 13.6 82.8 170.5 118.1 66.7 97.0 22.8 171.9 92.1 72.5 73.0 27.4 25.8 155.6 101.9 142.2 515.4 115.0 93.8 113.1 301.9 DDX23 "prp28, PRPF28, SNRNP100, U5-100K" ENSG00000174243 "DEAD-box helicase 23" Q9BUQ8 12 48829764-48852842 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038680, HPA039037" Approved Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA038680: AB_10795401, HPA039037: AB_2676317" "unprognostic (1.32e-3)" "unprognostic (8.90e-2)" "unprognostic (8.92e-2)" "unprognostic (7.12e-2)" "unprognostic (5.34e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.03e-5)" "unprognostic (3.54e-2)" "unprognostic (5.68e-2)" "unprognostic (2.19e-2)" "unprognostic (1.69e-1)" "unprognostic (8.34e-2)" "unprognostic (5.94e-2)" "unprognostic (9.78e-2)" "unprognostic (6.88e-2)" "unprognostic (2.59e-2)" "unprognostic (1.44e-1)" 26.1 26.5 29.5 35.6 34.2 19.4 27.2 32.8 35.6 26.7 32.8 23.3 27.5 27.9 31.0 22.3 31.0 31.1 25.2 25.1 29.8 20.3 25.2 37.7 27.7 35.2 26.5 25.3 36.2 30.4 32.2 28.1 34.4 25.0 29.9 32.6 24.7 31.1 27.0 44.4 30.6 32.3 29.4 24.1 40.0 30.6 24.9 32.0 46.8 28.2 29.8 38.9 28.9 47.9 12.0 11.5 19.6 13.3 11.2 19.8 10.6 22.0 50.5 24.0 25.4 24.0 16.6 25.5 27.4 21.1 31.1 19.8 49.1 29.5 27.9 30.1 22.7 29.4 20.0 52.0 24.9 26.7 43.7 27.6 37.0 43.0 22.1 12.9 37.3 33.7 16.0 22.4 33.0 19.8 21.4 25.5 24.8 48.9 25.0 22.6 30.7 35.3 35.4 35.7 31.4 24.0 37.8 28.4 22.2 18.4 31.1 29.6 17.3 27.4 31.5 11.4 25.7 30.8 34.3 22.8 23.6 17.3 11.6 21.7 18.9 26.3 33.7 20.0 26.3 12.9 17.1 11.1 19.6 19.5 13.3 19.8 12.0 14.5 17.6 10.8 11.4 14.0 16.9 11.9 11.2 8.9 11.5 13.1 10.6 29.5 34.2 32.8 35.6 29.8 20.3 26.5 25.3 25.0 32.0 23.8 25.5 22.4 12.7 11.4 16.9 17.1 22.9 44.2 31.8 12.2 23.6 22.5 13.3 22.3 6.9 21.0 23.3 23.3 33.5 24.6 16.2 21.2 17.4 16.3 16.7 14.3 13.4 17.8 9.9 4.1 22.7 15.0 13.5 24.4 22.7 24.3 28.9 31.6 20.8 10.2 24.0 19.4 18.4 33.8 36.1 13.2 22.2 24.2 23.9 17.1 DDX24 ENSG00000089737 "DEAD-box helicase 24" Q9GZR7 14 94048291-94081245 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 103.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002554 Uncertain Approved Nucleoli,Cytosol NA NA "Nucleoli, Cytosol" "HPA002554: AB_1078631" "unprognostic (7.48e-2)" "unprognostic (3.02e-2)" "unprognostic (8.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.31e-1)" "unprognostic (4.06e-3)" "unprognostic (8.81e-2)" "unprognostic (2.66e-3)" "unprognostic (2.77e-1)" "unprognostic (2.28e-2)" "unprognostic (1.60e-3)" "unprognostic (4.13e-2)" "prognostic favorable (3.06e-9)" "prognostic unfavorable (2.89e-4)" "unprognostic (6.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.66e-2)" 18.0 45.5 19.7 13.7 41.3 53.3 18.5 31.4 40.8 17.4 20.9 21.9 14.3 13.6 23.2 103.0 20.1 18.9 21.3 28.6 25.0 31.3 36.3 30.1 16.4 27.4 22.0 29.0 21.4 12.5 8.3 32.0 11.2 38.7 16.0 14.6 17.4 15.9 17.7 28.5 23.4 12.6 17.9 21.8 18.1 15.0 38.5 17.4 14.3 25.3 11.8 25.8 21.7 14.9 4.1 3.1 10.6 3.3 6.2 5.3 5.0 3.8 1.1 7.2 4.6 4.3 5.7 1.7 10.8 9.1 14.1 12.7 1.4 2.5 17.9 4.1 2.4 4.2 2.5 7.4 0.6 15.4 7.8 0.4 9.5 2.1 5.8 3.6 13.7 4.2 0.9 4.1 2.6 2.5 4.7 2.3 3.4 4.9 5.3 6.0 10.8 4.1 11.7 4.8 1.2 0.1 5.5 16.7 2.1 10.2 1.4 5.7 5.3 10.6 2.6 5.0 1.3 4.2 4.9 6.9 4.0 2.7 5.1 3.3 2.1 13.8 19.3 5.8 7.5 3.1 10.6 3.3 2.5 5.0 2.6 1.4 2.9 2.9 3.0 2.0 4.1 5.3 5.3 2.6 6.2 2.5 3.1 3.3 5.0 19.7 41.3 31.4 40.8 25.0 31.3 22.0 29.0 38.7 17.4 157.8 151.6 175.7 121.2 162.3 169.0 198.2 58.6 192.7 154.7 139.6 123.7 76.5 230.5 124.3 63.9 107.4 65.5 116.8 86.3 59.9 133.4 81.0 147.1 96.2 75.0 219.3 93.7 105.0 83.4 46.7 214.3 119.2 94.5 181.3 57.7 131.2 82.3 69.1 230.2 135.3 189.8 161.7 156.5 383.4 396.2 127.2 131.4 217.1 54.9 94.1 DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 17.3;testis: 64.2" "Group enriched" "Detected in some" 5 "Early spermatids: 250.3;Spermatocytes: 190.6" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "JURKAT: 16.8;NTERA-2: 11.4;SCLC-21H: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA020137: AB_1847552" "unprognostic (5.78e-3)" "unprognostic (9.75e-3)" "unprognostic (7.93e-2)" "unprognostic (5.09e-3)" "unprognostic (1.11e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" "unprognostic (6.24e-5)" "unprognostic (2.57e-1)" "unprognostic (2.44e-3)" "unprognostic (3.89e-1)" "unprognostic (3.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" 0.7 2.8 8.7 0.8 13.2 0.9 0.8 7.9 17.3 0.8 0.8 2.0 0.0 1.0 0.9 0.9 0.8 0.9 0.8 0.7 8.4 7.1 2.7 0.8 0.8 0.8 4.8 8.9 1.2 1.8 2.6 7.1 0.9 5.9 0.9 0.8 2.3 0.8 1.0 0.8 1.6 0.8 0.7 3.4 0.9 1.0 64.2 3.0 0.0 4.3 0.0 0.8 0.7 0.2 0.6 0.5 3.3 0.3 1.3 0.5 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.2 1.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.8 0.0 0.3 0.0 0.5 1.6 0.0 11.4 0.5 0.0 0.4 0.0 0.0 0.0 0.1 9.2 2.1 0.1 0.0 1.6 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 2.1 0.3 0.6 0.3 0.2 0.2 0.4 0.5 0.2 0.1 0.6 0.4 0.3 3.3 1.3 0.2 0.5 0.1 0.1 8.7 13.2 7.9 12.5 8.4 7.1 4.8 8.9 5.9 3.0 0.0 0.3 0.0 0.7 0.1 18.2 0.8 0.0 0.0 0.0 0.0 15.7 0.0 3.3 0.1 250.3 0.9 0.0 0.0 0.2 0.1 0.3 0.5 0.0 0.5 0.1 15.9 0.0 0.6 0.0 41.7 3.4 0.1 0.0 0.0 0.0 16.0 0.1 0.0 4.6 1.8 16.0 0.0 0.1 190.6 24.5 0.0 0.0 0.0 0.0 0.1 DDX27 "dJ686N3.1, DRS1" ENSG00000124228 "DEAD-box helicase 27" Q96GQ7 20 49219295-49244077 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047087 Uncertain Approved Nucleoli Yes No Nucleoli "HPA047087: AB_10964059" "unprognostic (4.47e-2)" "unprognostic (2.41e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (2.82e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (6.70e-7)" "unprognostic (2.28e-1)" "unprognostic (9.53e-2)" "unprognostic (2.74e-1)" "unprognostic (7.18e-2)" "unprognostic (5.84e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.26e-1)" "unprognostic (4.32e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" 22.0 22.5 21.9 33.0 23.2 40.9 23.6 34.8 26.3 24.3 26.4 16.3 20.4 23.2 26.2 19.1 26.5 23.9 27.1 19.2 22.6 17.3 25.9 21.0 20.1 32.3 19.9 18.8 37.4 27.3 25.9 25.6 23.9 21.2 22.0 22.1 14.4 22.9 24.3 32.9 27.8 33.6 20.0 20.7 34.1 22.9 25.0 24.0 30.6 23.5 19.4 35.3 24.0 27.2 30.4 28.0 22.2 24.2 18.2 26.7 18.6 20.2 19.3 9.9 7.6 11.0 10.2 28.2 13.5 11.1 42.6 19.8 62.7 22.7 24.1 25.2 10.9 37.0 28.8 22.0 21.6 31.7 8.5 12.9 18.3 16.2 30.4 16.2 23.1 21.5 10.8 25.4 24.8 19.1 9.7 7.0 19.0 24.9 13.4 13.8 13.6 24.3 30.6 18.7 24.8 25.1 21.0 24.6 22.2 15.4 15.7 12.9 15.3 37.6 54.4 22.6 14.3 28.8 26.9 8.8 27.4 24.1 22.9 28.0 15.3 16.5 31.6 17.5 18.5 17.6 11.1 19.8 22.2 21.7 21.2 22.8 29.4 20.6 19.7 23.3 30.4 26.7 20.3 8.1 18.2 24.2 28.0 26.3 18.6 21.9 23.2 34.8 26.3 22.6 17.3 19.9 18.8 21.2 24.0 26.8 43.1 49.7 41.1 31.7 24.0 22.7 20.4 40.2 45.5 31.4 13.7 49.9 16.6 46.3 131.4 24.2 38.6 0.0 38.0 41.7 28.8 24.4 110.8 20.3 29.9 27.0 29.7 12.3 16.4 107.1 36.8 41.8 18.6 43.3 30.5 32.3 46.2 37.4 31.8 34.2 27.6 25.8 29.7 67.4 60.0 28.1 62.4 50.1 43.2 37.1 DDX28 "FLJ11282, MDDX28" ENSG00000182810 "DEAD-box helicase 28" Q9NUL7 16 68021274-68023442 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Syncytiotrophoblasts: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041911, HPA053585" Approved Supported Nucleoli,Mitochondria,Cytosol No No "Mitochondria, Cytosol" Nucleoli "HPA041911: AB_10794161, HPA053585: AB_2682200" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.58e-1)" "unprognostic (8.69e-2)" "unprognostic (8.46e-2)" "unprognostic (9.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.63e-2)" "unprognostic (8.14e-3)" "unprognostic (8.53e-2)" "prognostic favorable (2.07e-10)" "unprognostic (1.58e-2)" "unprognostic (6.21e-2)" "unprognostic (2.23e-1)" "unprognostic (2.47e-1)" 9.8 12.7 6.2 6.7 8.3 19.7 7.1 6.0 12.9 8.3 7.2 6.4 6.8 5.2 7.5 7.3 9.7 7.1 7.0 9.2 5.2 5.9 8.9 12.4 5.8 18.4 6.4 5.1 8.6 13.3 6.8 4.6 17.1 6.6 6.1 6.0 7.8 6.3 5.2 16.2 9.9 7.9 5.3 3.0 11.1 7.0 11.5 2.7 14.6 10.2 7.3 10.6 8.0 4.8 17.8 18.0 22.9 19.1 17.0 22.9 16.6 6.1 9.2 4.5 5.4 6.3 3.5 10.6 4.2 6.3 10.7 7.6 8.9 9.8 23.2 6.5 5.2 5.8 11.2 6.4 10.2 6.3 3.1 10.6 8.4 4.8 9.2 8.5 13.1 9.0 6.9 11.2 8.8 8.1 3.7 5.9 15.7 14.9 3.6 4.7 13.8 13.7 18.5 11.1 6.3 6.8 13.5 4.2 24.8 7.5 7.2 9.5 6.4 17.2 4.9 9.3 5.4 9.5 14.4 4.2 4.7 4.0 6.7 6.9 8.2 9.9 22.3 5.8 10.1 6.4 17.7 19.1 22.9 15.7 18.8 17.3 12.6 14.6 16.9 18.0 17.8 22.9 16.9 6.3 17.0 18.5 9.0 13.8 16.6 6.2 8.3 6.0 12.9 5.2 5.9 6.4 5.1 6.6 2.7 6.0 5.0 7.5 13.5 8.1 4.8 3.1 2.5 2.7 5.7 3.5 0.0 24.0 11.6 9.5 5.9 6.0 1.7 0.0 8.5 9.4 4.2 3.1 3.5 9.7 15.4 3.2 4.6 4.3 10.3 3.1 4.6 6.6 6.8 11.8 2.8 7.2 7.2 4.5 3.2 14.6 3.4 12.9 4.1 20.6 15.1 9.4 83.5 10.1 5.8 10.3 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Intestinal endocrine cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" NA NA Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 6.8 6.9 8.2 15.3 11.2 6.0 12.3 18.4 8.5 7.5 6.6 9.4 12.6 5.0 8.9 8.8 9.8 8.8 7.5 5.4 6.3 6.3 8.4 9.2 12.0 15.1 9.1 5.7 16.9 17.3 10.0 8.8 5.8 9.8 9.2 8.0 7.4 12.7 12.6 12.9 14.0 7.2 12.7 12.9 8.7 6.8 15.2 8.3 6.8 22.7 10.8 13.8 7.2 12.6 5.0 4.5 1.9 2.7 3.1 6.9 3.0 7.0 13.2 6.4 8.8 7.9 7.1 12.6 7.6 7.5 12.0 9.2 14.6 14.6 17.7 6.9 7.1 12.5 19.8 20.2 8.9 9.7 10.8 7.5 9.6 11.7 7.6 9.5 17.0 7.8 6.3 12.2 12.3 17.3 4.6 7.8 13.2 17.6 6.9 9.9 15.2 11.8 9.3 15.9 21.0 13.5 12.5 11.4 20.3 10.9 6.8 11.6 8.3 13.9 12.4 10.5 7.8 25.9 5.0 6.6 20.4 9.2 11.5 11.7 3.4 10.7 13.8 7.3 10.8 15.3 0.0 1.9 1.9 5.7 2.7 4.7 4.2 5.5 4.4 4.5 5.0 6.9 5.1 0.3 3.1 1.9 2.8 3.6 3.0 8.2 11.2 18.4 8.5 6.3 6.3 9.1 5.7 9.8 8.3 6.0 5.9 3.4 3.1 4.9 3.4 3.1 0.0 6.7 15.9 7.0 3.9 4.6 1.7 4.1 2.1 3.9 0.7 0.0 4.6 5.8 2.6 4.1 1.1 3.2 4.6 1.6 23.6 3.1 2.4 2.4 16.7 2.8 1.7 4.6 3.7 1.5 4.7 0.0 12.4 4.3 3.1 0.0 2.1 11.2 15.7 5.5 2.5 4.1 5.7 2.6 DDX39A "BAT1L, DDX39, DDXL, URH49" ENSG00000123136 "DExD-box helicase 39A" O00148 19 14408819-14419383 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 60.7" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 238.8;Late spermatids: 232.5;Spermatocytes: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055334 Approved Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA055334: AB_2682787" "unprognostic (1.31e-1)" "prognostic favorable (6.86e-4)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (5.20e-2)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.81e-2)" "unprognostic (1.64e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (1.50e-10)" "unprognostic (1.55e-3)" "unprognostic (8.57e-2)" "unprognostic (3.92e-1)" "unprognostic (7.38e-3)" 10.9 8.5 7.2 20.6 11.4 41.4 10.5 9.1 7.9 8.2 10.9 11.0 4.4 13.0 9.4 7.2 15.9 7.0 8.1 7.8 6.6 6.1 9.7 12.1 10.3 31.2 12.6 5.0 7.4 8.8 3.0 7.4 10.5 10.0 7.3 8.9 5.2 7.9 4.4 7.9 10.6 12.8 6.8 9.4 23.4 10.4 60.7 10.3 39.9 8.4 16.3 26.1 10.3 8.8 36.7 36.6 7.7 28.5 21.5 39.7 33.6 32.9 27.1 13.9 26.9 5.7 4.2 13.6 14.7 8.1 30.6 18.9 27.5 17.9 63.7 15.6 12.1 16.4 20.4 34.2 23.8 12.5 22.3 17.9 68.4 31.6 19.7 10.1 37.2 30.6 5.8 5.4 19.8 8.1 4.5 16.0 23.4 42.0 28.1 17.0 39.9 63.7 55.2 26.6 32.2 41.5 44.2 24.6 37.3 10.9 27.1 32.4 17.9 10.9 22.8 16.5 9.5 25.2 36.3 14.9 27.1 16.9 44.5 32.8 29.2 51.2 65.6 30.4 40.6 27.0 6.8 25.9 7.7 35.6 28.5 30.5 36.7 28.4 28.2 36.6 33.2 24.9 26.7 7.7 21.5 23.4 22.6 39.7 33.6 7.2 11.4 9.1 7.9 6.6 6.1 12.6 5.0 10.0 10.3 14.9 27.9 70.7 37.1 67.5 10.3 9.4 17.8 21.4 18.2 5.2 0.0 37.6 31.5 37.9 238.8 33.8 44.6 23.3 57.3 97.5 36.2 30.0 89.1 10.6 78.7 11.1 24.6 27.6 51.6 232.5 24.5 64.4 47.2 70.3 24.3 13.8 42.5 28.1 17.7 22.6 3.9 19.4 54.6 336.3 94.8 62.0 50.1 65.4 35.5 32.5 DDX39B "BAT1, D6S81E, UAP56" ENSG00000198563 "DExD-box helicase 39B" Q13838 6 31530219-31542448 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 40.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034012, HPA055334, HPA058450" Enhanced Enhanced "Nuclear speckles" NA NA 120000 "Nuclear speckles" "CAB034012: AB_2243237, HPA055334: AB_2682787, HPA058450: AB_2683721" "unprognostic (2.78e-2)" "unprognostic (1.30e-2)" "unprognostic (6.86e-3)" "unprognostic (3.44e-2)" "unprognostic (3.22e-2)" "unprognostic (5.13e-3)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (1.11e-6)" "unprognostic (2.85e-1)" "unprognostic (1.72e-1)" "unprognostic (1.90e-2)" "prognostic favorable (1.43e-5)" 27.1 31.0 16.1 33.3 20.6 11.3 29.1 37.3 22.7 34.9 35.4 31.8 25.6 8.2 53.4 75.4 40.2 43.5 23.8 28.3 16.3 12.8 25.3 28.6 29.1 26.5 19.2 15.6 49.8 36.8 17.6 50.6 25.9 19.7 35.3 19.3 35.3 26.4 34.4 39.0 24.7 33.2 25.8 30.8 39.9 27.7 21.3 17.8 45.5 31.2 30.5 37.1 32.9 27.7 5.1 8.5 3.8 6.2 3.4 7.4 5.5 3.0 16.3 13.5 6.6 13.7 11.8 7.8 3.5 3.9 10.1 9.1 4.1 4.0 3.1 11.8 16.9 14.1 5.6 15.3 26.0 9.6 2.7 40.9 5.5 4.8 9.7 4.5 7.5 6.1 18.2 15.6 10.2 32.1 18.0 6.3 18.0 24.1 2.5 8.4 2.1 6.6 27.4 5.7 6.0 2.9 5.6 6.0 3.7 20.4 4.0 6.2 17.2 6.9 3.1 4.0 13.2 2.3 6.5 3.5 1.3 4.9 1.3 9.0 10.3 12.8 25.3 0.8 10.5 5.4 3.5 6.1 3.8 5.4 6.2 6.7 4.5 6.8 6.5 8.5 5.1 7.4 6.8 3.4 3.4 5.6 6.5 7.3 5.5 16.1 20.6 37.3 22.7 16.3 12.8 19.2 15.6 19.7 17.8 20.8 37.5 38.9 22.5 12.8 19.8 3.5 7.6 48.2 27.3 3.5 21.6 11.5 5.0 7.9 0.9 17.1 14.7 0.0 7.0 10.1 12.1 18.4 34.8 5.8 8.7 14.3 16.6 10.4 8.9 2.2 15.0 21.5 8.5 8.2 7.4 10.4 7.8 9.3 11.0 4.1 27.3 25.8 12.7 6.0 5.9 11.8 14.2 27.4 8.6 20.7 DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3, X-linked" O00571 X 41333284-41364472 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Late spermatids: 631.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol NA NA 110000 Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073" "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" 80.9 49.3 26.1 40.0 34.5 49.3 46.5 31.1 36.2 52.4 43.3 35.1 21.3 29.5 56.4 25.9 53.5 56.3 42.6 47.6 30.8 24.5 55.6 77.9 45.3 40.4 41.4 29.0 60.1 30.9 68.7 60.2 79.9 37.9 30.0 29.2 30.8 37.4 26.5 63.4 42.2 54.0 57.2 53.9 46.1 43.0 27.0 39.0 49.2 45.6 44.0 42.6 55.8 50.2 13.1 20.5 32.0 21.6 17.3 21.5 17.9 45.8 51.1 47.7 26.2 56.2 47.7 29.1 33.5 47.1 34.4 27.6 52.5 30.9 0.5 23.9 37.4 41.4 31.0 58.3 47.1 57.3 27.2 45.4 29.2 50.8 31.5 29.2 54.7 52.5 34.5 33.4 57.9 56.0 38.5 53.9 25.7 53.6 28.9 31.9 34.7 34.4 17.1 45.9 24.4 20.6 40.4 50.8 37.4 32.4 61.9 32.6 49.4 75.8 38.9 40.1 50.2 35.0 37.2 48.6 35.5 37.9 37.9 39.7 33.7 40.0 45.3 35.7 33.2 33.6 22.5 20.2 17.5 14.8 21.1 21.5 13.1 14.5 16.3 20.5 9.0 16.3 15.1 32.0 17.3 21.6 6.9 14.3 17.9 26.1 34.5 31.1 36.2 30.8 24.5 41.4 29.0 37.9 39.0 80.4 161.8 98.4 138.2 234.8 74.1 130.3 81.5 65.6 85.3 55.8 123.7 79.4 36.5 59.8 317.8 170.8 178.1 116.8 73.8 80.3 155.2 122.4 162.7 142.1 107.7 57.2 176.3 120.3 200.6 631.6 61.5 160.4 121.4 72.1 136.1 88.8 86.2 143.8 59.1 71.7 117.4 71.1 155.5 15.7 55.7 291.5 144.6 132.3 100.9 182.7 DDX3Y DBY ENSG00000067048 "DEAD-box helicase 3, Y-linked" O15523 Y 12904108-12920478 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 237.5;Late spermatids: 436.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 41.3;HEL: 42.1;U-266/84: 34.9;U-698: 30.7" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059583" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059583: " "unprognostic (3.89e-2)" "unprognostic (1.70e-1)" "prognostic favorable (4.70e-5)" "unprognostic (6.50e-2)" "unprognostic (4.74e-2)" "unprognostic (2.22e-2)" "unprognostic (4.17e-2)" "unprognostic (3.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-1)" "unprognostic (2.66e-2)" "unprognostic (7.87e-2)" 12.0 10.5 4.9 29.5 14.1 46.1 8.7 17.0 16.3 0.4 24.4 12.6 31.5 7.6 0.4 29.7 12.2 0.4 14.2 10.8 5.6 7.1 8.9 26.5 20.0 17.7 5.7 0.0 0.4 14.5 0.4 12.2 14.0 20.2 26.7 15.8 15.1 20.4 32.6 17.7 8.4 16.0 40.7 6.2 34.3 8.9 41.9 0.0 26.9 10.8 21.4 19.3 14.4 0.0 6.1 8.8 6.5 7.1 6.5 8.4 3.8 0.1 7.7 0.0 0.0 0.0 0.0 5.6 18.9 13.5 10.0 12.3 0.0 0.0 41.3 0.0 18.6 0.0 0.0 0.0 0.0 17.6 10.3 0.0 42.1 0.0 12.4 9.9 0.0 0.0 10.5 11.8 0.0 0.0 0.0 0.0 4.2 0.0 0.0 11.8 0.0 16.3 0.0 7.5 0.0 0.0 0.0 5.0 7.6 10.6 11.4 12.4 0.0 0.0 0.0 13.8 12.7 0.0 9.8 13.5 15.5 0.0 0.0 12.4 22.3 34.9 30.7 1.9 0.0 0.0 1.6 6.2 5.7 8.4 7.1 7.7 6.1 6.4 7.1 8.8 5.9 7.8 6.5 6.5 6.5 4.6 2.5 5.7 3.8 4.9 14.1 17.0 16.3 5.6 7.1 5.7 0.0 20.2 0.0 44.7 70.4 32.3 85.6 83.6 48.4 24.1 12.7 117.8 50.0 8.7 39.3 34.0 5.0 8.7 237.5 56.2 0.0 0.0 0.2 11.4 45.1 53.9 88.1 0.6 15.6 39.7 15.3 28.3 37.0 436.7 35.9 93.0 25.3 15.4 3.7 57.0 8.2 0.0 37.1 14.7 46.4 19.4 59.7 36.2 65.8 70.3 31.6 51.1 0.0 62.4 DDX4 VASA ENSG00000152670 "DEAD-box helicase 4" Q9NQI0 5 55738017-55817157 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 60.4" "Group enriched" "Detected in some" 4 "Early spermatids: 435.1;Late spermatids: 140.2;Spermatocytes: 312.4" "Cancer enriched" "Detected in single" 37 "testis cancer: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;HEK 293: 1.6;NB-4: 1.0;PC-3: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB026170, HPA037763, HPA037764" Enhanced NA NA "CAB026170: , HPA037763: AB_2675652, HPA037764: AB_2675653" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.54e-1)" "unprognostic (2.58e-1)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (5.35e-2)" "unprognostic (3.91e-1)" "unprognostic (3.77e-2)" "unprognostic (3.28e-1)" "unprognostic (5.73e-2)" "unprognostic (5.43e-7)" "unprognostic (4.84e-2)" "unprognostic (1.12e-1)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 60.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.4 0.0 0.1 0.0 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 435.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.2 5.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.5 0.0 0.0 0.0 0.0 312.4 73.7 0.0 0.0 0.0 0.0 0.0 DDX41 "ABS, MGC8828" ENSG00000183258 "DEAD-box helicase 41" Q9UJV9 5 177511577-177517469 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017911, HPA048803" Supported Supported Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA017911: AB_1847558, HPA048803: AB_2680527" "unprognostic (2.52e-1)" "unprognostic (1.51e-1)" "unprognostic (7.57e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.61e-2)" "unprognostic (4.21e-3)" "unprognostic (2.60e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (2.21e-6)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" 17.9 22.7 27.0 25.1 30.7 17.2 16.5 22.8 39.2 19.1 21.2 16.9 18.5 25.5 19.5 16.5 23.0 22.1 17.1 15.3 29.3 20.1 23.7 29.3 16.8 19.9 22.1 24.8 21.2 18.0 22.2 15.1 22.1 27.4 16.3 15.4 19.0 19.0 17.5 36.6 21.7 26.8 16.7 14.8 21.9 19.7 16.8 15.4 24.9 22.9 18.2 23.5 19.6 18.4 15.9 22.5 16.4 22.8 18.6 20.6 18.0 21.2 24.3 13.3 15.7 13.7 16.3 44.9 19.1 11.6 14.1 10.4 39.6 19.8 23.9 29.1 18.0 24.7 17.4 17.4 43.7 9.6 57.0 21.8 30.3 24.7 23.5 18.2 31.3 32.2 15.9 15.4 13.3 17.9 12.0 17.9 23.9 26.2 17.0 16.5 45.8 26.1 15.4 23.5 19.9 19.7 28.4 16.2 28.1 15.7 24.8 15.8 17.3 20.3 27.0 22.8 8.1 18.9 45.8 19.1 25.7 15.2 16.4 29.7 20.5 24.0 40.7 28.2 34.6 16.9 10.6 22.8 16.4 16.1 21.5 20.6 15.9 16.0 15.3 22.5 14.1 14.8 15.5 7.7 18.6 21.4 10.2 15.6 18.0 27.0 30.7 22.8 39.2 29.3 20.1 22.1 24.8 27.4 15.4 23.8 19.1 26.4 18.3 18.7 17.4 7.1 25.5 14.7 15.9 8.7 2.0 40.7 34.9 39.1 8.4 20.3 22.6 23.3 34.4 49.6 19.5 16.0 28.9 16.3 43.7 7.9 10.9 12.3 22.2 16.2 13.8 21.8 11.8 41.5 23.7 15.8 29.9 20.1 19.8 28.9 9.4 12.9 20.6 24.2 23.2 17.8 31.4 22.3 26.3 16.3 DDX42 "RHELP, RNAHP, SF3b125, SF3B8" ENSG00000198231 "DEAD-box helicase 42" Q86XP3 17 63773603-63819317 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023447, HPA023571, HPA025941" Approved Enhanced "Nuclear speckles" NA NA "Nuclear speckles" "HPA023447: AB_1847560, HPA023571: AB_1847561, HPA025941: AB_1847562" "unprognostic (3.46e-1)" "unprognostic (7.11e-2)" "unprognostic (8.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.90e-1)" "unprognostic (2.54e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.26e-4)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (7.35e-2)" "unprognostic (1.55e-2)" 32.4 28.2 27.1 26.3 39.4 24.2 32.5 34.1 40.7 39.1 31.2 33.7 20.9 23.0 39.2 30.7 26.1 34.4 35.1 25.6 25.6 26.7 23.0 25.7 26.4 27.5 29.6 35.8 43.5 41.8 36.8 26.2 30.7 34.1 39.0 28.0 28.8 34.0 35.6 44.7 29.2 26.7 37.7 27.3 26.9 30.5 28.6 21.5 33.2 26.1 21.8 33.7 42.6 25.4 7.6 5.0 8.4 4.4 6.7 6.6 2.8 30.9 32.6 29.3 30.1 29.8 24.1 31.7 30.5 27.5 28.0 27.5 30.6 20.5 43.4 12.0 34.1 23.2 24.9 33.1 27.1 37.1 12.7 21.7 32.6 31.6 37.1 29.4 37.7 22.4 30.7 25.9 25.3 30.8 23.8 27.7 22.5 36.2 18.4 28.3 25.3 36.0 21.1 28.0 24.9 17.5 31.5 50.5 22.2 25.5 36.6 18.5 35.1 23.0 41.6 26.0 43.3 28.5 31.2 29.4 41.4 25.3 16.7 35.8 20.6 16.5 40.0 21.3 20.9 21.7 2.6 3.9 8.4 6.2 3.2 6.6 4.1 5.2 6.1 5.0 7.6 6.6 6.4 2.9 6.7 4.4 3.0 3.1 2.8 27.1 39.4 34.1 40.7 25.6 26.7 29.6 35.8 34.1 21.5 74.5 54.3 18.8 21.3 27.7 38.2 41.5 22.9 75.0 64.8 34.9 35.3 28.4 11.6 24.6 7.1 33.8 21.4 0.0 23.3 19.4 28.9 33.4 29.0 26.8 20.2 47.7 39.1 29.4 29.5 9.8 45.1 26.6 13.5 54.1 34.3 42.7 31.2 24.6 47.4 18.9 43.5 38.8 36.0 46.6 53.5 26.0 22.9 19.5 33.8 26.7 DDX43 "CT13, DKFZp434H2114, HAGE" ENSG00000080007 "DEAD-box helicase 43" Q9NXZ2 6 73394748-73417569 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 35.2" "Group enriched" "Detected in many" 6 "Spermatocytes: 50.6;Spermatogonia: 31.3" "Cancer enriched" "Detected in many" 15 "testis cancer: 13.0" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 9.0;CAPAN-2: 15.1;HHSteC: 4.2;MCF7: 2.8;U-2 OS: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA031381 Enhanced NA NA "HPA031381: AB_10601885" "unprognostic (4.03e-3)" "unprognostic (8.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.19e-1)" "unprognostic (3.59e-4)" "unprognostic (1.64e-2)" "unprognostic (3.11e-2)" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (3.08e-1)" "unprognostic (1.19e-3)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (1.58e-1)" "unprognostic (8.78e-2)" 1.3 0.7 0.6 1.0 0.7 0.7 1.9 0.4 0.8 0.8 2.6 1.2 2.1 1.4 1.0 0.4 1.1 0.7 6.1 1.2 0.7 0.6 0.8 1.0 1.6 0.9 1.0 0.0 2.9 1.9 0.1 0.7 5.7 3.3 1.8 0.7 1.5 4.3 2.2 0.4 1.4 1.7 3.0 1.9 1.2 2.4 35.2 0.7 0.4 1.8 1.3 1.9 1.7 0.7 2.3 0.8 2.9 0.9 1.6 3.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.5 0.0 0.0 0.0 0.1 15.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 2.9 3.3 0.9 2.6 2.3 2.5 2.8 0.8 2.3 1.3 0.4 0.6 1.6 0.8 0.2 1.4 0.7 0.6 0.7 0.4 0.8 0.7 0.6 1.0 0.0 3.3 0.7 3.0 4.8 0.5 1.1 2.4 0.3 0.4 0.0 1.4 3.4 0.0 0.0 6.5 0.0 0.4 2.2 2.2 0.0 0.0 0.8 2.9 1.1 0.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 3.3 2.0 1.8 3.3 1.0 0.0 0.4 1.3 0.0 1.1 1.4 0.9 0.0 0.4 50.6 31.3 1.3 5.0 2.5 0.0 0.7 DDX46 "FLJ25329, KIAA0801, Prp5, PRPF5" ENSG00000145833 "DEAD-box helicase 46" Q7L014 5 134758771-134855133 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036554, HPA057501" Supported Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA "Nuclear speckles" "Nucleoli fibrillar center" "HPA036554: AB_10673621, HPA057501: AB_2683449" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "prognostic favorable (9.01e-6)" "unprognostic (7.00e-2)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (2.04e-3)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (5.05e-2)" "unprognostic (9.21e-2)" "unprognostic (6.02e-2)" "unprognostic (9.70e-3)" "unprognostic (4.36e-2)" "unprognostic (4.35e-2)" "unprognostic (1.64e-2)" "unprognostic (4.50e-2)" 22.2 21.8 18.8 29.4 23.8 22.7 22.7 39.0 24.8 25.1 21.4 17.5 18.6 19.0 26.8 19.8 23.7 21.0 15.8 18.3 17.7 13.0 22.9 22.7 21.6 26.6 22.9 15.1 25.8 24.2 27.2 37.5 22.1 21.7 19.0 24.2 12.8 23.9 23.3 46.6 26.3 23.0 24.6 27.8 30.0 22.2 17.8 25.9 40.4 22.1 21.0 29.1 23.1 28.9 27.0 23.5 34.6 19.9 19.4 20.4 9.7 26.0 23.9 17.1 22.2 6.7 7.5 23.6 17.5 13.6 18.5 20.9 36.2 19.1 32.9 15.1 11.7 19.7 16.2 25.1 16.7 21.9 22.1 22.8 39.6 26.2 14.6 5.8 35.9 21.4 6.7 9.1 19.5 11.0 7.9 14.6 26.6 33.6 14.2 13.7 12.4 30.9 14.0 23.5 15.2 10.8 27.0 44.7 16.6 10.1 22.6 20.3 19.4 24.5 11.6 12.6 20.8 18.2 20.6 18.1 19.7 13.7 15.0 34.6 11.2 30.3 43.7 13.6 34.2 12.4 25.7 19.9 27.6 20.0 17.5 18.0 22.0 19.6 19.8 15.2 27.0 20.4 20.3 34.6 19.4 15.7 23.5 17.1 9.7 18.8 23.8 39.0 24.8 17.7 13.0 22.9 15.1 21.7 25.9 71.5 105.7 105.4 97.5 101.1 127.7 65.7 58.6 77.6 91.0 97.7 78.5 115.9 48.0 74.4 33.8 94.6 63.5 46.7 93.1 132.3 81.3 98.0 97.2 105.0 85.5 114.4 88.5 70.0 102.8 19.1 103.6 110.8 54.0 131.7 71.2 91.8 98.0 56.1 106.4 70.1 171.0 97.0 97.9 194.9 273.4 119.7 131.5 115.4 84.3 132.0 DDX47 "DKFZp564O176, FLJ30012, HQ0256, RRP3" ENSG00000213782 "DEAD-box helicase 47" Q9H0S4 12 12813316-12829981 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Ductal cells: 21.7;Exocrine glandular cells: 15.4;monocytes: 16.2;Pancreatic endocrine cells: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014855 Approved Supported Nucleoli NA NA Nucleoli "HPA014855: AB_1847567" "unprognostic (3.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.75e-2)" "unprognostic (2.38e-1)" "unprognostic (4.91e-2)" "unprognostic (5.84e-4)" "unprognostic (1.96e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-3)" "unprognostic (2.79e-1)" "unprognostic (3.49e-3)" "unprognostic (6.55e-9)" "unprognostic (1.68e-1)" "unprognostic (1.27e-1)" "unprognostic (3.24e-1)" "unprognostic (8.20e-6)" 29.3 24.1 19.9 21.6 25.6 31.0 29.1 27.4 26.9 26.7 26.2 28.2 21.4 16.0 33.7 21.0 28.9 27.5 17.9 22.6 20.0 19.4 29.6 38.1 23.2 26.1 28.2 19.9 33.7 31.0 25.8 23.8 27.6 25.1 29.2 24.2 25.5 27.1 27.7 40.6 28.1 20.4 34.1 21.4 25.6 28.0 26.8 29.8 29.7 39.4 27.9 33.7 35.7 26.7 22.0 25.0 3.5 19.1 16.6 26.0 14.0 39.7 17.2 16.9 13.7 16.7 16.4 28.9 17.1 19.7 36.6 34.3 26.0 25.7 20.5 6.7 23.2 22.7 26.0 24.2 19.7 41.3 28.9 17.4 18.7 12.8 14.8 14.2 21.3 12.1 15.8 18.8 21.7 18.0 28.8 28.1 16.2 18.1 4.6 20.0 14.2 17.2 14.8 74.3 18.5 10.6 19.2 32.9 12.4 22.3 28.7 7.4 18.8 20.8 13.4 17.0 43.8 5.4 16.1 12.6 14.8 35.9 9.5 25.7 6.5 11.8 37.1 15.7 11.2 17.0 3.3 14.4 3.5 21.8 19.1 26.0 22.0 19.4 20.1 25.0 21.2 25.8 24.2 1.7 16.6 18.2 14.7 18.7 14.0 19.9 25.6 27.4 26.9 20.0 19.4 28.2 19.9 25.1 29.8 3.0 8.0 0.9 2.5 1.9 0.8 0.1 0.0 10.7 13.6 0.0 0.0 1.3 1.7 21.7 0.1 1.6 2.0 0.0 15.4 1.6 1.0 1.6 11.5 0.8 0.7 0.0 4.6 1.3 0.6 0.0 0.6 1.3 0.0 16.2 4.5 1.4 18.4 2.9 0.4 0.6 1.3 6.5 0.5 0.2 0.6 1.6 1.1 5.0 6.2 2.0 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919675-18928633 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA Mitochondria "HPA041870: AB_2677717, HPA048093: AB_2680262" "unprognostic (3.51e-1)" "prognostic favorable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavorable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 14.8 16.8 17.6 17.3 16.9 28.3 18.0 17.0 30.7 15.3 15.8 19.0 14.8 19.5 15.6 13.2 23.4 16.5 12.2 18.2 19.2 12.9 15.5 25.6 13.0 19.3 15.7 14.8 15.7 26.8 13.0 11.1 23.3 16.2 15.5 10.3 13.5 24.3 15.8 27.2 23.6 18.7 12.7 16.8 16.7 15.7 19.7 16.3 23.4 18.8 16.6 18.7 16.4 15.6 8.2 25.0 13.5 19.5 14.1 14.0 9.7 15.8 16.5 6.7 21.0 9.8 7.9 25.2 10.1 6.8 17.9 14.5 18.8 16.1 20.8 30.9 10.0 5.7 13.6 14.9 13.8 5.1 6.3 39.6 10.2 17.9 16.3 23.3 26.1 14.2 15.7 13.3 14.2 15.0 5.0 8.1 16.6 19.2 14.9 6.3 35.5 18.9 12.2 21.8 17.2 40.3 21.0 11.2 22.5 9.6 10.0 23.6 24.3 13.3 13.2 16.1 3.7 13.5 12.6 10.4 8.7 9.8 31.5 16.5 19.6 23.4 19.0 11.0 30.2 13.6 10.5 17.7 13.5 12.8 19.5 10.6 8.1 9.7 9.6 25.0 8.2 9.7 10.2 7.9 14.1 12.6 11.2 14.0 9.7 17.6 16.9 17.0 30.7 19.2 12.9 15.7 14.8 16.2 16.3 3.0 7.7 21.6 16.0 20.0 17.5 12.5 15.3 8.1 12.5 17.4 3.9 39.6 31.5 25.8 28.0 10.8 42.3 0.0 45.8 41.7 17.9 16.3 18.4 13.9 29.8 9.5 24.8 8.0 19.8 81.0 19.8 18.3 25.3 26.2 20.9 16.0 25.6 30.6 18.7 21.4 20.9 19.4 20.2 29.7 36.4 24.7 35.2 15.8 30.7 17.3 DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64499616-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043, HPA071154" Supported Supported Nucleoplasm,Nucleoli No No 150000 "Nucleoplasm, Nucleoli" "CAB005868: AB_446484, HPA020043: AB_1847572, HPA071154: " "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" 91.6 61.4 46.9 80.0 68.0 108.3 94.7 61.6 58.9 81.6 81.1 53.3 104.2 27.4 106.7 94.5 64.5 96.9 101.4 53.9 48.5 30.6 53.1 68.0 84.8 70.9 62.8 44.1 74.0 49.3 88.9 110.5 56.6 73.1 59.5 55.4 50.9 62.2 103.6 77.6 59.7 54.7 113.1 71.0 67.6 69.0 39.7 57.8 82.1 81.1 77.7 69.3 91.0 63.9 46.9 59.6 66.4 66.2 40.3 60.8 109.8 55.1 20.8 63.0 39.9 58.4 55.0 40.1 54.7 70.6 67.1 67.2 22.5 33.8 80.9 31.4 71.8 47.8 32.9 67.8 62.9 75.9 28.7 48.7 52.6 15.9 17.2 42.8 66.9 56.1 61.9 54.3 61.3 47.8 37.4 71.6 69.9 41.7 69.1 51.7 32.8 139.9 19.5 36.7 50.9 64.3 87.6 66.6 56.9 41.1 26.5 44.3 74.3 53.1 51.5 66.6 56.7 48.2 37.7 50.3 40.8 45.6 43.9 56.6 38.6 76.1 142.8 43.2 32.9 48.1 66.4 62.5 66.4 53.7 56.9 60.8 46.9 42.9 51.7 59.6 46.8 44.5 43.1 37.8 40.3 66.2 37.0 50.2 109.8 46.9 68.0 61.6 58.9 48.5 30.6 62.8 44.1 73.1 57.8 497.3 661.1 481.3 1231.3 781.2 369.6 221.7 262.4 725.4 624.4 350.7 316.1 372.7 283.5 416.6 432.3 643.3 503.6 116.8 366.6 307.8 528.8 417.0 836.7 222.3 399.0 397.3 638.0 483.1 539.2 80.3 384.6 631.0 410.0 779.1 366.4 576.1 376.0 445.4 411.5 208.8 514.0 485.0 599.5 374.0 341.8 652.0 741.9 719.3 310.9 1106.4 DDX50 "GU2, GUB, MGC3199, RH-II/GuB" ENSG00000107625 "DExD-box helicase 50" Q9BQ39 10 68901278-68946847 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037388, HPA037389, HPA058196" Approved Enhanced Nucleoli NA NA Nucleoli "HPA037388: AB_10671752, HPA037389: AB_2675450, HPA058196: AB_2683635" "unprognostic (2.05e-1)" "unprognostic (3.36e-1)" "unprognostic (9.90e-2)" "unprognostic (9.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-3)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (8.78e-2)" "unprognostic (4.57e-2)" "unprognostic (1.44e-1)" "unprognostic (4.22e-3)" "unprognostic (1.22e-2)" "unprognostic (2.38e-2)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" 25.0 17.8 16.7 25.5 19.2 14.7 24.8 20.8 17.0 26.5 25.3 13.1 24.0 12.9 30.0 22.6 24.0 23.0 17.5 20.3 15.7 15.0 18.6 16.1 16.4 24.5 17.6 15.0 35.3 24.1 24.9 35.2 23.0 16.1 30.0 18.1 12.6 19.5 25.0 26.6 18.3 17.4 31.9 18.3 22.0 19.9 25.6 17.3 33.0 26.1 21.5 25.7 35.4 27.2 14.2 10.3 10.7 12.2 13.8 20.2 10.9 19.3 12.5 22.2 27.5 18.9 24.8 14.2 20.7 22.8 18.7 17.7 28.0 16.9 25.2 12.5 18.2 11.7 17.4 21.5 15.2 23.5 22.1 16.3 13.5 12.4 12.2 19.1 28.1 16.9 19.0 15.9 17.8 49.8 33.6 15.0 22.0 24.1 15.4 23.0 15.5 26.9 27.0 12.9 18.6 28.1 23.3 25.3 4.6 14.7 11.6 15.5 21.4 15.2 17.8 22.8 21.6 20.7 18.3 13.0 14.6 17.1 16.5 28.1 20.9 18.8 21.4 15.7 29.4 8.5 5.5 7.8 10.7 15.0 12.2 18.3 13.6 18.5 15.4 10.3 14.2 20.2 17.7 2.7 13.8 9.6 10.2 16.1 10.9 16.7 19.2 20.8 17.0 15.7 15.0 17.6 15.0 16.1 17.3 17.9 17.1 30.4 30.5 10.5 42.7 23.6 20.4 29.4 34.2 19.2 37.3 35.2 48.0 24.1 57.6 24.3 8.9 0.0 21.8 33.0 25.7 18.5 40.6 13.5 20.5 35.0 15.5 22.1 18.1 12.1 33.6 21.7 11.8 39.7 18.2 20.9 20.8 18.4 36.7 25.1 51.1 19.4 28.1 54.0 56.0 12.5 34.4 41.5 21.3 16.8 DDX51 ENSG00000185163 "DEAD-box helicase 51" Q8N8A6 12 132136594-132144335 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039503 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Nucleoli" Cytosol "HPA039503: AB_10796328" "unprognostic (2.84e-3)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-1)" "unprognostic (8.66e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (4.88e-1)" "unprognostic (3.05e-3)" "unprognostic (5.31e-2)" "unprognostic (3.97e-2)" "unprognostic (2.48e-1)" "unprognostic (4.69e-2)" "unprognostic (3.28e-1)" "unprognostic (1.65e-3)" 10.5 8.5 12.7 12.7 17.1 17.2 10.3 23.5 18.9 8.8 8.4 11.8 10.6 7.8 11.5 12.2 8.5 12.4 10.0 8.1 11.6 9.9 9.5 7.2 8.9 11.1 10.5 16.9 19.6 14.8 10.1 9.8 7.2 11.8 9.3 7.3 8.9 10.7 12.4 13.8 18.0 8.2 10.4 10.5 10.6 9.3 6.7 12.0 9.5 9.9 7.1 10.4 9.3 8.6 2.5 2.3 2.6 2.1 1.6 2.0 1.0 6.2 10.1 4.2 5.3 4.0 3.9 8.0 4.8 2.9 7.2 3.0 6.2 3.1 10.9 4.2 2.9 1.7 6.6 10.5 7.7 3.5 2.6 10.1 12.9 5.4 2.0 4.9 9.0 7.5 3.4 5.7 4.0 3.6 8.1 3.8 12.2 9.5 3.6 2.1 6.2 11.0 18.5 7.4 5.3 17.4 13.1 5.8 12.1 4.9 5.0 10.3 5.4 5.3 7.5 5.3 3.7 6.6 8.3 6.7 2.7 8.3 6.6 11.1 10.2 5.9 12.8 5.6 6.9 6.3 1.1 2.1 1.2 2.0 1.0 0.7 1.5 1.3 0.9 0.6 2.5 1.2 1.6 2.6 1.6 1.0 2.3 0.6 1.0 12.7 17.1 23.5 18.9 11.6 9.9 10.5 16.9 11.8 12.0 3.0 15.9 3.0 6.8 11.1 27.9 4.0 10.2 4.0 13.6 3.5 23.6 6.0 1.7 4.0 0.9 7.7 3.5 0.0 4.5 4.9 6.5 7.3 5.8 6.4 4.9 31.8 8.1 7.4 6.2 0.7 7.8 5.7 10.1 3.6 8.3 11.1 5.4 7.0 7.8 2.9 27.4 0.0 6.4 5.7 9.4 12.3 3.4 6.9 12.1 5.8 DDX52 ROK1 ENSG00000278053 "DExD-box helicase 52" Q9Y2R4 17 37609739-37643464 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 210.7" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056173 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA056173: AB_2683056" "unprognostic (1.05e-2)" "unprognostic (1.85e-1)" "prognostic favorable (9.41e-4)" "unprognostic (4.26e-2)" "unprognostic (9.96e-3)" "unprognostic (6.77e-2)" "prognostic unfavorable (2.44e-6)" "unprognostic (5.10e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (6.95e-2)" "unprognostic (5.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" 6.4 4.5 4.3 5.3 5.5 9.1 4.6 8.1 6.5 6.9 6.1 4.8 5.0 5.9 7.8 10.7 6.7 3.5 5.0 3.0 4.5 9.4 7.1 4.2 5.1 5.4 3.1 6.3 4.4 6.2 8.8 5.8 6.5 6.1 6.0 4.0 4.1 4.8 6.7 6.0 10.6 4.8 6.2 5.7 4.8 4.8 4.9 8.7 5.7 5.8 6.1 6.0 6.9 4.0 5.7 3.5 4.2 3.5 4.7 1.5 4.8 9.9 1.0 9.8 5.5 4.9 4.2 6.5 5.8 8.6 8.3 5.0 1.8 2.7 4.5 4.3 1.8 4.4 10.9 7.1 11.5 6.5 12.3 6.1 6.2 4.0 5.4 7.8 3.2 5.1 7.3 5.6 6.9 4.1 9.8 2.7 0.8 1.9 5.0 1.5 11.7 4.0 5.6 2.7 0.4 7.6 8.6 5.0 9.7 5.4 7.2 5.8 7.8 1.8 4.8 5.7 3.4 6.0 6.6 7.0 4.4 3.6 7.4 2.4 3.9 5.5 5.7 4.9 5.5 3.4 3.2 3.5 4.2 4.2 3.3 3.6 4.0 3.5 2.3 4.0 3.4 4.7 2.8 3.5 2.4 5.7 3.1 1.5 38.7 19.5 26.1 27.2 30.7 28.6 28.7 28.1 28.1 38.7 26.2 31.4 30.7 29.9 64.6 210.7 26.3 24.7 0.0 45.3 25.7 21.9 24.4 26.5 32.8 22.8 44.5 25.2 29.4 23.8 70.2 22.7 23.7 16.9 47.7 26.7 23.2 47.9 21.0 22.6 32.3 32.6 25.8 12.6 28.9 57.6 29.1 20.9 34.4 36.5 43.1 DDX53 "CAGE, CT26" ENSG00000184735 "DEAD-box helicase 53" Q86TM3 X 22999961-23003589 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 11.5" "Cell type enriched" "Detected in some" 5 "Early spermatids: 47.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 4.6;K-562: 6.3;RPMI-8226: 3.3;U-2197: 2.1;U-266/84: 14.1" "Low region specificity" "Detected in many" HPA003186 Supported Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA003186: AB_1078637" "unprognostic (5.76e-1)" "unprognostic (1.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.0 8.8 0.0 0.0 0.0 0.0 0.0 DDX54 "APR-5, DP97, MGC2835" ENSG00000123064 "DEAD-box helicase 54" Q8TDD1 12 113157174-113185479 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028244, HPA070786" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA028244: AB_10603885, HPA070786: AB_2686311" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (8.54e-2)" "unprognostic (8.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (2.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.83e-2)" "unprognostic (1.15e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" 17.2 17.6 9.2 20.7 12.8 25.4 17.2 9.9 13.6 17.9 16.4 12.4 18.1 20.3 18.0 19.4 19.5 17.2 17.9 20.1 8.8 7.9 22.3 28.6 14.0 19.9 8.1 9.4 22.4 27.0 18.3 7.4 22.6 10.0 16.6 9.0 13.4 17.4 13.9 45.4 18.7 19.4 14.8 8.1 22.2 16.1 11.4 8.6 26.6 23.1 21.6 22.2 16.7 17.5 12.1 13.3 8.0 15.2 11.9 13.0 10.0 26.8 28.1 10.5 19.3 7.0 8.5 27.1 14.6 13.6 20.0 11.0 28.9 13.1 34.9 17.2 12.2 14.9 20.0 18.6 19.0 7.6 20.0 22.8 20.9 15.1 19.7 12.4 34.9 24.8 13.9 15.1 19.3 11.9 16.4 16.3 21.2 30.3 12.5 10.2 24.8 30.0 49.8 24.5 18.9 20.0 22.3 15.5 35.6 10.9 28.1 13.6 12.4 20.7 31.8 13.2 9.0 27.3 27.3 12.1 17.0 19.0 20.1 30.4 18.3 20.8 39.2 15.0 19.5 17.8 8.0 10.0 2.3 12.4 15.2 13.0 11.6 11.4 12.2 13.3 12.1 11.8 12.5 0.6 11.9 9.8 10.0 9.4 10.0 9.2 12.8 9.9 13.6 8.8 7.9 8.1 9.4 10.0 8.6 29.8 28.0 32.1 27.0 15.3 20.2 12.4 20.4 10.7 21.6 12.2 2.0 51.4 21.6 35.0 0.9 19.7 30.2 23.3 43.1 46.0 18.7 23.5 24.3 35.5 34.5 25.4 27.1 15.4 31.7 2.1 27.3 23.0 11.8 23.4 28.6 23.8 38.0 38.2 22.6 34.9 18.1 6.5 18.9 15.4 18.9 17.1 60.5 37.3 38.2 32.3 DDX55 KIAA1595 ENSG00000111364 "DEAD-box helicase 55" Q8NHQ9 12 123602077-123620941 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039962, HPA044101" Approved Enhanced Nucleoplasm,Nucleoli NA NA Nucleoli Nucleoplasm "HPA039962: AB_2676774, HPA044101: AB_2678810" "unprognostic (1.14e-1)" "unprognostic (2.30e-2)" "unprognostic (2.29e-1)" "unprognostic (3.71e-3)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.11e-9)" "unprognostic (1.60e-1)" "unprognostic (4.49e-2)" "unprognostic (7.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-3)" "prognostic unfavorable (8.97e-12)" "unprognostic (9.15e-3)" "unprognostic (2.94e-1)" "unprognostic (3.47e-2)" "unprognostic (1.23e-3)" 15.0 13.5 12.3 16.4 14.0 27.7 16.3 21.4 13.9 13.0 13.2 15.7 16.2 12.0 14.7 13.2 14.2 15.0 11.8 8.8 11.4 10.9 10.2 17.8 11.2 19.9 15.6 10.3 17.5 25.9 13.8 20.3 12.3 14.4 14.4 14.5 11.9 15.2 12.6 12.6 21.4 12.9 11.9 10.5 18.8 11.6 11.2 14.8 16.9 12.2 12.5 16.5 11.9 23.1 13.4 12.8 7.3 10.0 12.2 15.7 8.5 10.1 14.5 11.1 11.2 9.6 7.6 16.8 12.6 4.6 11.3 7.8 16.4 7.5 15.1 10.1 5.5 10.2 12.6 16.9 9.4 13.2 11.3 15.3 20.4 16.0 12.1 7.3 25.0 16.1 6.4 10.0 13.4 15.5 8.8 8.1 12.3 20.8 8.0 7.9 10.5 24.5 34.1 17.2 11.8 14.4 18.5 11.9 9.8 7.9 17.7 13.2 11.0 10.3 13.4 17.2 9.7 23.8 16.2 8.3 9.8 12.9 15.9 15.6 14.8 18.3 27.4 9.3 18.0 16.6 2.8 9.2 7.3 12.0 10.0 12.7 13.4 11.6 12.5 7.5 11.3 15.7 14.7 5.6 12.2 5.9 12.8 9.1 8.5 12.3 14.0 21.4 13.9 11.4 10.9 15.6 10.3 14.4 14.8 20.8 11.5 9.0 8.3 9.7 18.5 2.2 7.6 13.4 10.3 7.0 21.6 11.2 6.6 9.6 42.5 10.5 5.1 46.7 10.4 13.9 10.1 8.4 24.3 8.5 12.6 14.3 6.9 6.2 6.6 50.7 15.8 7.9 6.8 4.6 10.5 15.6 11.6 7.0 13.8 5.4 25.4 6.5 8.5 17.9 19.6 14.8 6.4 10.2 8.3 7.8 DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565417-44575051 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019749, CAB037320" Uncertain Supported "Nucleoli,Mitotic chromosome" NA NA Nucleoli "Mitotic chromosome" "CAB037320: , HPA019749: AB_1847579" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.00e-2)" "unprognostic (1.93e-1)" "unprognostic (6.08e-3)" "unprognostic (2.12e-3)" "prognostic unfavorable (1.38e-5)" "unprognostic (5.17e-2)" "unprognostic (2.76e-1)" "unprognostic (7.07e-2)" "unprognostic (1.00e-2)" "unprognostic (6.01e-3)" "prognostic unfavorable (8.41e-7)" "unprognostic (2.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.50e-1)" "unprognostic (4.90e-2)" 12.8 12.0 10.3 12.4 11.9 12.4 9.2 13.6 18.9 11.9 10.0 12.2 8.6 11.9 12.8 10.3 13.1 12.6 12.5 9.3 10.6 9.9 17.7 29.2 8.9 13.2 10.4 9.3 15.0 22.5 13.1 11.9 12.3 12.2 14.1 9.0 11.0 16.9 11.5 16.9 16.3 11.4 8.4 8.8 12.1 10.6 14.6 10.9 14.5 13.8 16.7 15.1 9.2 10.3 12.8 16.0 6.9 16.5 15.7 12.3 12.7 7.6 20.5 1.6 4.4 2.0 2.0 6.8 7.3 3.7 8.3 7.3 13.2 7.6 13.5 9.5 2.7 11.4 13.1 3.3 7.3 1.5 5.0 20.8 8.9 13.0 10.1 3.6 9.3 5.0 2.9 5.3 7.4 4.6 1.5 4.2 5.0 18.3 3.8 5.3 10.1 4.7 8.6 11.1 6.6 19.3 3.8 7.2 5.3 4.7 8.2 5.2 8.4 9.6 15.0 5.5 1.3 10.9 9.6 8.9 6.8 9.9 4.6 18.3 12.4 19.0 19.4 7.5 11.4 9.5 6.9 11.8 4.3 9.9 15.3 12.3 11.5 10.7 11.1 16.0 12.8 12.3 10.3 0.4 15.7 16.5 7.7 10.1 12.7 10.3 11.9 13.6 18.9 10.6 9.9 10.4 9.3 12.2 10.9 14.9 25.3 16.0 20.1 15.1 25.2 10.8 12.7 24.1 34.2 21.0 13.7 48.6 23.2 34.9 39.1 23.8 26.9 0.0 28.4 38.8 18.4 15.9 27.7 27.7 31.4 6.4 17.7 18.4 10.1 30.0 19.5 17.4 13.5 32.5 19.6 20.6 31.1 20.1 18.7 40.8 23.2 12.9 20.6 30.2 29.0 17.3 39.5 18.7 27.0 18.1 DDX58 "DKFZp434J1111, FLJ13599, RIG-I" ENSG00000107201 "DExD/H-box helicase 58" O95786 9 32455705-32526324 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 45.5;BJ hTERT+ SV40 Large T+ RasG12V: 47.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012643, HPA047193" Uncertain Approved "Plasma membrane,Cytosol" No No "Plasma membrane" Cytosol "CAB012643: , HPA047193: AB_2679978" "unprognostic (1.10e-1)" "unprognostic (4.65e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (8.15e-2)" "unprognostic (4.57e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.00e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.22e-2)" "unprognostic (3.68e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" 27.7 8.2 5.7 14.5 7.9 5.6 11.3 4.2 5.7 9.9 9.5 5.2 9.1 7.2 12.7 11.7 10.8 7.6 10.3 7.1 6.0 5.1 14.7 8.5 13.7 14.3 6.3 4.5 9.2 7.7 6.6 10.2 14.8 7.5 12.1 8.1 5.5 12.4 5.8 8.3 10.7 16.1 10.8 7.7 13.8 8.0 4.5 6.4 35.4 13.0 7.4 9.7 9.9 9.4 4.9 2.0 24.8 5.7 6.1 6.5 3.0 2.9 1.1 1.6 0.9 3.9 4.1 2.5 1.8 8.9 45.5 47.6 1.2 2.6 0.8 3.2 1.6 14.7 2.4 1.8 2.0 6.4 7.3 0.6 2.8 2.5 2.0 3.2 1.8 2.2 2.8 0.7 5.2 1.6 3.5 8.3 2.2 0.6 0.6 6.0 0.4 2.6 4.7 1.3 0.6 1.3 2.4 1.2 0.3 6.9 1.6 1.2 0.8 2.6 1.1 5.0 1.1 1.9 1.6 9.4 1.4 1.3 1.1 0.9 0.1 0.5 0.6 2.0 0.8 0.9 8.5 3.8 10.3 6.2 5.7 5.5 4.8 5.6 5.6 2.0 4.9 5.1 5.6 24.8 6.1 3.9 0.1 6.5 3.0 5.7 7.9 4.2 5.7 6.0 5.1 6.3 4.5 7.5 6.4 20.8 9.1 5.4 4.4 3.8 3.7 4.4 2.5 8.1 6.8 1.8 2.0 4.5 0.0 17.2 2.0 14.5 14.6 0.0 10.6 6.7 5.1 4.6 4.7 6.4 5.0 6.4 2.9 8.6 6.9 0.0 6.1 6.7 0.0 2.8 2.9 9.4 12.8 5.8 5.6 6.5 2.7 6.5 6.6 0.5 1.5 4.6 2.1 9.2 1.9 4.3 DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669969 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Nucleoplasm, Actin filaments" "HPA047166: AB_2679966" "unprognostic (1.99e-1)" "unprognostic (1.60e-1)" "unprognostic (3.44e-2)" "unprognostic (4.87e-2)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.40e-3)" "unprognostic (2.43e-3)" "unprognostic (4.16e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (5.98e-2)" 14.0 14.4 12.1 16.4 14.8 23.7 22.7 16.7 11.2 14.5 11.6 10.8 12.6 8.1 15.8 17.6 12.0 13.8 11.4 18.0 12.0 9.9 13.6 15.1 11.8 15.1 15.1 6.7 17.1 21.6 13.9 10.7 46.5 12.8 14.1 12.5 15.0 19.4 12.9 28.6 21.5 12.4 14.0 17.2 20.9 10.4 9.9 14.5 18.5 15.1 10.1 13.2 12.8 12.7 12.2 9.5 23.1 16.2 12.4 15.6 7.9 9.4 10.9 12.7 10.6 5.7 10.0 28.3 10.6 9.5 11.4 9.3 3.4 11.1 9.6 5.4 8.4 9.3 9.0 7.1 10.8 8.1 30.3 7.3 7.3 14.0 10.1 11.5 10.5 13.6 10.7 16.4 8.6 23.5 9.5 8.7 13.8 9.2 14.3 11.0 10.9 6.3 15.8 13.4 5.7 8.9 5.3 8.8 18.5 12.2 11.0 7.7 20.0 16.8 17.5 18.6 17.2 15.1 14.8 7.8 9.6 5.4 9.5 10.9 10.9 14.2 12.7 9.2 6.6 16.4 23.1 10.3 19.0 13.0 8.9 10.6 12.2 10.9 11.7 8.5 11.5 11.3 10.3 18.2 12.4 16.2 9.5 15.6 7.9 12.1 14.8 16.7 11.2 12.0 9.9 15.1 6.7 12.8 14.5 17.9 19.0 14.5 11.1 14.3 3.3 15.9 5.1 10.7 7.9 7.0 2.0 18.5 13.3 7.5 2.0 15.9 7.4 0.0 7.3 22.7 10.8 10.1 19.7 6.4 11.5 6.4 1.2 10.4 8.6 0.2 7.5 11.7 5.0 17.2 10.7 8.5 7.9 8.0 12.7 8.4 6.0 0.0 12.3 12.1 19.0 13.7 36.6 13.1 8.8 8.6 DDX6 "HLR2, RCK" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747766-118791149 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease mutation, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cytoplasmic bodies" Cytosol "CAB004668: AB_436960, HPA024201: AB_10603562, HPA026644: AB_1847582" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "prognostic unfavorable (6.56e-4)" "unprognostic (3.43e-1)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (7.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-3)" "unprognostic (1.88e-1)" "unprognostic (9.58e-2)" "unprognostic (4.55e-2)" 29.8 23.0 25.0 24.1 41.0 43.3 25.1 41.9 39.2 26.9 23.2 29.4 14.5 17.1 30.1 22.9 31.8 23.4 17.5 26.8 25.5 25.1 22.8 24.6 23.4 32.2 21.9 27.1 38.2 27.9 30.9 43.2 26.1 29.6 24.9 20.8 25.4 26.8 22.9 43.8 23.9 24.1 27.8 30.4 30.6 21.2 19.9 24.0 46.0 27.9 19.4 42.8 33.0 25.7 12.2 6.5 17.8 10.3 7.2 12.6 5.7 11.9 16.3 26.3 25.9 23.1 23.7 17.2 16.2 21.3 15.1 14.4 23.7 18.4 27.4 17.1 26.5 15.1 19.1 30.6 23.7 24.4 20.6 6.1 52.9 10.5 19.3 15.3 37.9 20.4 25.0 17.5 22.4 36.4 19.9 24.0 18.5 24.3 39.8 21.3 32.6 27.5 17.6 18.7 16.9 12.0 30.3 21.3 21.9 17.7 31.0 17.4 24.0 30.6 24.6 9.7 20.6 28.7 14.9 27.4 25.1 13.8 14.3 16.3 12.4 16.1 32.7 10.0 18.2 21.4 10.5 4.1 11.6 10.1 5.7 12.6 11.4 9.9 10.4 4.7 12.2 12.4 10.8 17.8 7.2 10.3 6.5 8.9 5.7 25.0 41.0 41.9 39.2 25.5 25.1 21.9 27.1 29.6 24.0 56.6 60.1 71.3 62.3 26.9 78.4 105.7 35.7 40.2 43.3 41.8 47.1 31.3 26.6 28.5 3.7 65.3 48.0 46.7 30.5 30.1 37.5 44.5 49.8 37.6 33.8 58.8 82.4 58.9 51.1 8.2 50.0 42.0 32.1 73.1 55.4 81.3 38.8 65.4 42.5 35.6 75.0 38.8 41.9 66.1 72.8 26.7 64.0 103.8 45.4 65.9 DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216293-168318807 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 1: 32.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 22.8;BJ hTERT+ SV40 Large T+ RasG12V: 22.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA046952 Approved Supported "Intermediate filaments,Cytosol" No No Cytosol "Intermediate filaments" "HPA046952: AB_10963572" "unprognostic (4.05e-2)" "unprognostic (2.87e-1)" "unprognostic (7.22e-3)" "unprognostic (7.71e-2)" "unprognostic (2.30e-1)" "unprognostic (2.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.15e-2)" "unprognostic (3.06e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (3.35e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (2.48e-1)" "unprognostic (3.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.44e-1)" 18.0 8.3 4.1 18.5 5.0 4.4 9.0 1.3 3.8 11.4 14.8 4.3 5.1 8.8 10.8 15.2 10.7 8.1 11.5 8.5 3.7 3.5 10.0 8.8 21.6 18.7 4.2 3.2 20.3 5.5 8.8 6.7 25.5 5.6 11.6 14.3 9.0 15.6 6.2 5.6 7.9 16.7 11.2 6.1 18.9 29.2 5.7 3.9 23.2 14.5 6.0 9.3 8.2 7.2 4.1 2.5 3.2 6.3 7.6 10.0 3.5 5.6 1.2 2.8 1.1 2.1 7.8 3.2 1.9 13.7 22.8 22.1 0.0 12.4 0.0 1.1 3.0 10.5 4.7 0.3 4.5 6.6 4.3 0.6 8.8 4.8 0.0 10.3 3.3 2.2 7.0 2.0 5.8 1.3 5.5 8.5 4.2 0.0 1.7 2.8 0.3 5.0 2.4 0.5 0.8 1.6 3.4 1.5 0.1 6.7 3.4 0.6 0.6 3.6 1.0 13.7 0.2 0.9 4.2 5.6 1.4 1.5 0.5 1.4 1.0 0.2 0.0 4.3 3.8 4.0 3.2 2.8 2.6 8.5 5.1 10.0 4.1 6.7 8.0 2.5 3.3 6.8 8.5 2.8 7.6 6.3 0.2 5.5 3.5 4.1 5.0 1.3 3.8 3.7 3.5 4.2 3.2 5.6 3.9 32.8 6.2 5.0 4.0 3.8 0.7 7.1 10.2 14.7 12.5 12.2 0.0 6.4 5.0 7.0 1.7 10.3 10.7 0.0 5.9 8.5 5.0 3.8 26.5 3.8 5.8 0.0 2.9 15.4 4.1 1.4 7.5 8.8 3.3 0.0 13.6 8.0 8.7 7.2 8.9 3.3 3.0 6.5 3.8 0.9 0.7 2.4 2.4 10.1 5.8 3.1 DDX60L FLJ31033 ENSG00000181381 "DExD/H-box 60 like" Q5H9U9 4 168356735-168537786 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 22.5" "Group enriched" "Detected in all" 4 "granulocytes: 22.5;monocytes: 7.8" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 23.3" "HPA043211, HPA055501" Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA043211: AB_10794390, HPA055501: AB_2682838" "unprognostic (8.86e-2)" "unprognostic (2.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.20e-2)" "unprognostic (1.05e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (4.19e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.13e-1)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.69e-1)" 12.7 5.0 2.8 13.1 3.1 33.0 9.9 1.4 3.2 7.2 8.4 3.2 2.7 6.0 9.2 7.9 3.8 6.9 6.7 6.0 2.4 2.4 4.5 6.0 25.8 17.7 3.8 1.4 7.3 5.1 4.4 5.2 32.6 3.4 5.0 6.5 6.8 7.0 5.7 3.3 4.3 14.0 5.3 4.2 11.9 9.5 2.7 3.1 25.3 5.8 3.5 8.1 4.9 6.8 1.6 2.4 22.5 7.8 1.7 3.7 1.6 6.1 3.6 1.4 0.6 3.7 10.8 7.0 6.2 13.1 23.3 16.2 0.0 14.5 0.1 0.3 6.3 12.7 2.4 0.6 3.7 6.8 3.5 0.5 13.6 4.0 0.3 4.5 5.5 3.4 3.0 1.1 8.4 0.7 4.9 16.4 3.1 0.2 0.1 14.9 0.1 4.9 3.5 0.3 0.6 3.1 2.7 3.2 0.0 2.2 3.6 0.2 1.9 11.0 1.3 6.2 0.2 1.0 7.8 17.5 1.2 8.2 2.9 2.1 5.9 0.9 0.0 4.1 16.5 1.8 1.6 4.0 3.5 2.7 6.3 3.7 0.9 2.7 2.7 2.4 1.6 2.2 2.3 22.5 1.7 7.8 0.0 3.6 1.6 2.8 3.1 1.4 3.2 2.4 2.4 3.8 1.4 3.4 3.1 8.9 7.9 0.0 2.1 0.9 1.3 8.1 5.1 12.0 3.4 3.5 21.6 4.5 0.0 6.8 10.7 13.1 11.6 0.0 8.7 29.4 7.0 2.6 8.1 5.4 22.5 0.0 0.0 9.2 23.2 3.6 3.1 29.7 0.0 26.2 13.2 3.2 17.0 14.0 3.9 3.3 16.8 6.5 3.3 0.5 1.3 2.0 5.9 8.7 3.8 1.4 DESI2 "C1orf121, CGI-146, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244652935-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles NA NA Vesicles "HPA049950: AB_2680969" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (5.40e-2)" "unprognostic (1.95e-2)" "unprognostic (7.62e-2)" "unprognostic (1.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.47e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (4.52e-2)" "unprognostic (8.27e-2)" "unprognostic (2.27e-2)" "unprognostic (9.49e-2)" 16.4 13.3 6.4 16.1 12.9 10.5 19.9 17.4 6.5 18.5 19.4 7.6 14.6 10.9 27.7 12.8 14.7 12.4 12.7 27.6 6.5 5.8 9.6 13.5 28.4 11.5 7.7 3.2 16.3 10.0 14.8 11.8 20.4 6.9 14.9 13.1 17.8 12.1 14.8 16.2 11.6 17.5 23.2 6.6 14.3 14.9 49.2 7.4 16.8 25.8 14.5 14.7 16.8 14.4 8.0 4.8 9.1 4.0 3.9 5.6 1.2 24.5 9.2 18.1 15.6 20.8 21.8 22.7 14.3 25.0 14.3 13.2 16.3 11.7 43.8 19.6 17.8 8.3 10.8 22.1 16.2 19.7 14.9 16.2 11.1 6.9 12.2 18.2 19.0 13.4 15.1 22.1 19.0 24.0 13.8 20.0 19.9 16.7 24.4 21.4 4.3 17.4 10.2 41.0 23.3 22.4 12.4 27.4 16.6 10.9 10.3 16.0 21.5 20.3 10.1 17.8 15.2 10.5 14.5 21.7 16.3 17.0 22.0 24.8 24.8 31.9 25.8 13.1 20.6 29.6 4.6 3.0 9.1 4.0 3.9 4.2 8.0 4.2 5.6 4.8 4.7 5.5 5.4 2.5 3.9 4.0 4.2 5.2 1.2 6.4 12.9 17.4 6.5 6.5 5.8 7.7 3.2 6.9 7.4 80.4 41.8 24.3 26.4 49.1 34.2 21.2 28.1 13.4 25.0 17.4 19.6 25.5 18.3 18.2 124.1 27.0 18.6 0.0 29.2 33.3 29.2 39.4 6.9 20.2 21.2 38.1 15.0 23.4 25.4 74.9 32.2 17.4 15.1 26.2 17.8 21.8 26.3 25.9 48.8 13.5 25.0 38.8 32.4 160.4 90.2 36.1 36.2 20.2 25.5 51.9 DHX15 "DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p" ENSG00000109606 "DEAH-box helicase 15" O43143 4 24517441-24584550 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047047 Approved Enhanced "Nuclear speckles" NA NA 30000 "Nuclear speckles" "HPA047047: AB_2679916" "unprognostic (4.46e-3)" "unprognostic (2.47e-2)" "prognostic favorable (5.74e-4)" "unprognostic (3.35e-1)" "unprognostic (5.30e-2)" "unprognostic (5.74e-2)" "unprognostic (2.06e-3)" "unprognostic (5.53e-3)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (8.68e-3)" "unprognostic (7.77e-3)" "unprognostic (2.51e-3)" "unprognostic (2.19e-1)" "unprognostic (1.59e-1)" "unprognostic (5.41e-3)" 34.3 29.6 23.2 32.1 27.5 42.5 33.0 38.0 27.6 31.1 31.9 29.5 24.1 22.8 37.5 23.4 40.8 30.6 22.9 32.6 22.8 18.8 30.0 29.5 31.2 34.7 29.4 17.7 36.5 35.9 42.5 32.8 39.2 27.4 28.2 37.7 22.4 34.1 24.9 36.5 36.0 30.7 30.7 22.8 32.4 32.4 21.0 27.9 58.3 33.5 31.6 43.0 35.4 35.7 20.3 26.7 31.4 24.1 24.5 28.8 17.7 30.1 29.6 49.1 24.3 24.2 23.6 29.3 35.2 31.0 37.2 37.0 30.0 36.7 55.5 21.7 28.8 43.4 25.3 63.1 42.4 58.0 20.3 29.9 48.1 32.4 24.2 14.2 49.5 33.2 19.7 25.5 36.2 24.5 23.9 31.0 26.2 45.0 22.4 42.1 22.8 64.9 33.2 53.4 30.2 26.9 42.8 57.6 25.9 44.3 43.5 42.2 26.4 27.3 26.3 24.7 36.8 28.8 25.7 28.3 31.6 20.8 23.8 41.0 17.0 28.6 66.4 21.1 40.5 37.5 31.4 20.2 18.8 21.1 20.6 28.8 19.9 23.6 24.5 26.7 20.3 24.9 23.7 9.7 24.5 24.1 17.8 25.8 17.7 23.2 27.5 38.0 27.6 22.8 18.8 29.4 17.7 27.4 27.9 71.5 53.1 27.6 56.7 87.6 28.3 26.0 28.1 49.5 71.7 26.2 21.6 64.7 31.5 51.9 23.9 49.1 52.6 0.0 36.1 61.0 55.6 53.7 55.4 42.4 39.4 25.4 58.2 47.3 49.9 11.8 36.5 48.1 45.5 36.1 59.4 22.6 47.7 37.4 37.8 26.9 28.3 25.8 58.7 54.9 45.5 87.4 73.8 35.5 57.5 79.7 DHX16 "DBP2, DDX16, Prp2, PRPF2" ENSG00000204560 "DEAH-box helicase 16" O60231 6 30653119-30673037 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051455 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA051455: AB_2681491" "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (4.36e-3)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "unprognostic (3.11e-1)" "unprognostic (8.58e-2)" "unprognostic (1.24e-2)" "unprognostic (9.77e-3)" "unprognostic (4.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-1)" "unprognostic (8.73e-3)" 12.8 15.8 12.7 16.8 14.0 12.1 14.4 16.8 14.9 13.3 16.2 12.3 15.8 19.3 16.3 13.3 14.9 14.4 14.6 12.4 11.4 7.1 18.0 19.2 13.9 18.2 13.6 8.6 15.6 19.1 24.3 16.6 11.3 13.5 16.4 13.6 14.4 18.0 18.2 23.2 18.4 19.8 16.4 11.0 22.6 14.9 36.8 14.9 18.8 21.6 12.1 16.5 13.2 15.3 4.5 5.9 8.7 7.6 7.1 5.8 4.4 9.7 4.1 6.0 9.3 6.8 4.7 7.1 8.1 6.5 11.7 9.1 9.2 4.0 7.4 7.6 7.2 8.8 9.4 9.8 7.3 9.4 10.4 8.1 7.3 7.4 5.1 6.0 18.4 9.8 4.2 7.1 9.5 8.2 4.7 3.6 9.4 12.1 7.3 5.8 8.1 5.2 9.3 5.7 5.2 5.7 8.8 6.4 7.9 6.2 7.7 7.1 5.8 9.0 9.5 6.6 5.6 7.2 5.6 3.9 7.5 5.2 7.3 11.8 8.7 13.4 7.2 3.6 10.1 9.6 6.0 6.0 8.7 5.8 7.5 5.3 4.4 5.3 4.8 5.9 4.5 4.4 5.0 5.8 7.1 7.6 4.8 5.1 4.4 12.7 14.0 16.8 14.9 11.4 7.1 13.6 8.6 13.5 14.9 20.8 18.1 15.7 10.1 9.6 11.0 13.3 7.6 41.5 26.1 5.2 37.3 16.9 8.3 15.7 71.1 9.2 13.9 23.3 16.1 16.8 9.6 8.3 39.5 7.5 12.3 4.8 5.8 9.8 10.5 36.4 13.3 13.6 5.0 22.6 11.7 9.8 18.4 24.6 11.7 7.8 49.9 19.4 12.2 73.1 30.6 9.4 16.0 16.6 10.1 9.1 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256245-55307722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" NA NA Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 14.6 16.2 15.1 12.2 16.6 9.8 16.3 22.0 16.9 17.3 18.4 9.2 20.2 11.3 17.4 12.8 18.5 13.6 11.7 22.1 12.8 9.6 22.4 20.6 15.2 11.8 13.7 11.9 13.8 15.3 30.3 30.7 17.7 16.3 18.9 13.3 7.8 15.2 24.3 31.8 15.9 14.7 18.5 13.1 14.3 14.8 10.2 16.6 15.6 20.9 12.0 11.9 19.9 14.4 18.5 25.9 32.4 19.6 16.0 18.8 6.3 22.1 15.6 13.0 17.2 21.5 18.0 16.0 23.7 18.7 17.4 18.1 12.7 14.5 13.0 21.6 26.5 22.8 16.4 20.5 23.0 25.0 5.2 11.6 11.9 14.5 8.9 12.3 7.9 12.7 15.8 14.2 18.6 11.2 12.2 22.9 10.6 14.5 9.9 20.8 15.3 13.9 8.0 11.1 6.4 17.5 6.8 20.5 21.4 15.1 15.3 12.1 8.3 23.4 12.9 11.7 13.7 18.3 14.7 20.0 16.0 13.5 14.3 17.2 9.5 14.3 17.6 19.7 13.8 18.0 32.4 16.3 15.9 13.5 16.4 15.1 18.5 16.9 15.0 12.1 17.6 18.8 15.8 15.2 16.0 19.6 25.9 13.9 6.3 15.1 16.6 22.0 16.9 12.8 9.6 13.7 11.9 16.3 16.6 65.5 35.2 25.3 32.1 33.4 77.9 67.4 48.4 33.5 66.0 61.1 39.3 58.7 46.4 45.2 32.2 35.9 31.5 93.5 53.9 43.6 42.1 40.8 30.1 40.5 36.0 39.7 36.9 21.5 25.0 13.6 43.1 37.1 27.0 36.1 33.2 34.7 50.0 25.9 49.8 84.5 77.5 51.8 44.2 87.3 127.3 41.5 68.0 27.7 35.1 33.6 DHX30 "DDX30, FLJ11214, KIAA0890" ENSG00000132153 "DExH-box helicase 30" Q7L2E3 3 47802909-47850195 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034806 Supported Supported Mitochondria,Cytosol NA NA Mitochondria Cytosol "HPA034806: AB_10601364" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "prognostic favorable (1.37e-6)" "unprognostic (4.12e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.22e-1)" 18.4 18.7 22.1 18.5 31.1 23.6 18.3 31.2 43.5 22.3 17.8 26.9 15.5 17.3 23.3 14.8 21.0 24.8 17.9 21.3 19.1 19.8 18.6 19.3 16.7 22.0 20.4 28.0 27.1 21.2 37.3 24.8 20.6 23.6 20.4 13.0 22.0 20.4 23.6 27.1 26.2 16.1 18.8 15.3 21.2 18.7 54.4 18.4 23.8 20.1 15.2 16.9 18.6 17.6 9.9 13.0 9.8 10.5 8.2 16.1 11.6 8.1 20.7 20.5 21.1 9.5 7.9 14.0 15.4 13.2 26.6 19.2 23.8 17.4 26.5 12.1 15.0 18.5 12.5 30.3 21.5 9.5 18.0 36.3 23.1 30.5 23.2 16.5 21.5 24.0 13.8 13.7 28.1 19.8 10.5 17.3 24.5 32.5 17.1 12.4 22.0 27.3 23.6 22.8 10.8 35.4 18.2 11.0 23.5 13.3 20.7 16.9 22.5 15.0 21.4 11.1 10.3 15.0 22.6 12.0 16.1 20.9 18.1 28.2 20.7 25.8 24.0 16.7 18.8 19.9 9.8 10.1 7.2 15.0 10.3 13.0 9.9 12.7 16.1 13.0 9.3 12.1 13.0 1.5 8.2 10.5 7.8 14.3 11.6 22.1 31.1 31.2 43.5 19.1 19.8 20.4 28.0 23.6 18.4 35.7 44.3 33.3 22.5 16.1 46.6 31.3 35.7 42.8 28.4 48.8 41.2 35.6 56.3 33.4 93.4 33.1 32.4 23.3 31.3 18.8 20.4 23.6 23.1 43.3 30.5 55.6 38.5 23.4 27.7 89.2 23.0 28.0 18.6 25.2 23.6 39.2 38.5 29.6 28.3 56.9 46.8 32.3 19.4 136.8 41.1 17.3 24.7 23.5 30.9 22.7 DHX32 "DDX32, DHLP1, FLJ10694, FLJ10889" ENSG00000089876 "DEAH-box helicase 32 (putative)" Q7L7V1 10 125836337-125896436 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048872 Approved NA NA "HPA048872: AB_2680540" "unprognostic (1.05e-1)" "unprognostic (3.02e-1)" "unprognostic (3.97e-2)" "unprognostic (6.40e-2)" "unprognostic (2.40e-1)" "unprognostic (3.57e-1)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (2.85e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (9.49e-5)" "prognostic unfavorable (6.34e-4)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (8.62e-2)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" 15.4 16.3 7.8 10.2 9.7 4.0 18.0 7.3 11.5 10.5 20.1 12.1 11.2 11.4 10.6 14.0 20.6 8.6 13.1 27.3 7.6 7.5 12.1 14.5 10.1 16.8 10.3 7.0 18.1 23.5 11.7 9.5 19.3 8.9 13.1 24.5 12.8 17.9 8.4 16.0 18.5 16.1 9.1 9.8 12.2 21.7 20.6 9.5 8.0 13.6 10.7 10.0 13.0 12.6 6.8 2.3 3.2 3.5 4.5 5.3 0.9 27.3 15.1 10.2 21.0 13.6 12.6 18.3 12.1 28.2 11.1 12.5 3.5 27.2 0.1 9.1 14.1 12.3 20.0 4.6 20.4 9.2 13.8 9.1 3.4 7.8 5.3 15.1 6.6 11.3 12.4 21.5 10.9 24.6 20.0 16.1 0.1 9.4 0.1 10.7 12.3 0.1 10.4 7.7 13.4 10.5 0.1 16.6 5.9 16.2 12.7 1.4 7.5 11.2 20.3 16.6 13.9 7.4 5.9 14.4 8.7 5.3 11.0 10.7 10.8 10.5 0.2 15.7 0.1 4.4 0.3 3.0 3.2 2.7 3.5 2.2 6.8 1.3 1.1 2.3 3.2 5.3 2.1 0.1 4.5 1.7 1.3 0.4 0.9 7.8 9.7 7.3 11.5 7.6 7.5 10.3 7.0 8.9 9.5 14.9 12.1 4.7 11.4 4.4 12.6 22.1 10.2 6.7 13.6 7.0 21.6 16.9 13.3 27.9 69.4 9.2 15.7 0.0 32.3 23.7 6.3 19.4 11.5 9.6 10.3 11.1 4.1 6.7 7.3 19.5 9.8 6.1 6.8 4.6 41.9 30.9 41.9 20.1 15.9 13.5 14.5 12.9 8.2 31.9 5.6 6.0 37.0 4.4 19.5 21.7 DHX33 "DDX33, DKFZp762F2011, FLJ21972" ENSG00000005100 "DEAH-box helicase 33" Q9H6R0 17 5440912-5469060 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073875 Supported Supported Nucleoli NA NA Nucleoli "HPA073875: AB_2686638" "unprognostic (4.96e-2)" "unprognostic (1.35e-1)" "unprognostic (3.41e-2)" "unprognostic (2.51e-2)" "unprognostic (9.24e-2)" "unprognostic (1.90e-1)" "unprognostic (1.49e-2)" "unprognostic (6.15e-2)" "unprognostic (3.11e-2)" "unprognostic (3.80e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.03e-1)" "unprognostic (4.66e-1)" "unprognostic (3.55e-1)" "unprognostic (4.69e-2)" "unprognostic (3.37e-2)" 10.0 10.4 11.6 11.0 14.6 7.0 12.9 15.8 22.0 9.0 8.7 14.1 8.6 8.6 12.4 7.9 11.2 11.2 9.2 7.7 9.7 7.0 8.2 13.4 8.0 10.1 11.0 13.2 11.1 12.1 16.5 7.3 11.5 10.3 10.0 10.7 11.3 10.4 10.8 13.9 12.5 8.7 11.1 8.0 11.1 9.6 10.1 11.7 8.4 9.5 9.4 10.3 9.6 9.5 3.7 3.4 2.6 3.5 3.0 2.5 0.7 10.3 15.4 9.8 17.6 4.1 8.4 12.3 10.3 6.4 15.9 12.8 9.6 4.5 25.5 7.2 8.4 6.3 12.3 20.0 16.1 20.4 8.2 19.2 10.1 12.6 16.3 8.2 13.5 9.1 7.1 9.8 16.9 23.2 4.7 11.7 12.4 13.4 12.6 8.7 7.3 13.6 7.4 21.8 6.9 7.8 18.3 14.5 13.8 7.2 8.1 8.6 12.4 10.7 9.3 15.9 8.7 7.2 7.1 10.9 11.0 11.6 8.7 21.7 4.7 5.1 13.1 7.8 16.0 15.7 0.6 3.5 1.8 2.2 1.4 2.1 2.5 2.5 1.4 1.4 3.7 2.5 2.4 2.6 3.0 1.3 3.4 1.8 0.7 11.6 14.6 15.8 22.0 9.7 7.0 11.0 13.2 10.3 11.7 11.9 10.4 3.0 12.0 18.7 16.4 13.4 20.4 5.3 11.4 7.0 19.6 7.3 1.7 6.5 40.0 11.1 5.7 0.0 13.2 7.9 14.1 7.4 3.5 25.4 5.4 12.7 8.7 12.3 15.3 4.8 7.2 8.2 13.5 1.0 10.6 14.7 9.5 3.5 9.2 6.3 10.1 0.0 11.3 11.2 15.2 17.3 4.2 4.5 11.0 10.8 DHX34 "DDX34, KIAA0134" ENSG00000134815 "DExH-box helicase 34" Q14147 19 47349281-47382704 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Late spermatids: 48.6;Spermatocytes: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 13.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042159, HPA043558" Uncertain Uncertain "Nucleoplasm,Intermediate filaments" NA NA "Nucleoplasm, Intermediate filaments" "HPA042159: AB_10963066, HPA043558: AB_10961262" "unprognostic (1.26e-1)" "unprognostic (5.17e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (8.63e-6)" "unprognostic (9.14e-2)" "unprognostic (4.74e-2)" "unprognostic (5.11e-2)" "unprognostic (4.76e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (7.38e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-1)" "unprognostic (7.21e-3)" 6.8 6.9 12.6 11.0 11.5 20.3 6.6 18.7 13.3 8.2 5.9 9.1 8.9 7.7 10.4 5.3 8.3 9.0 5.7 6.0 11.2 6.4 7.2 10.9 8.9 7.9 12.3 8.4 13.3 12.9 7.8 14.2 7.8 11.4 8.9 4.6 8.5 9.9 8.3 7.8 11.8 7.0 6.6 10.5 13.5 6.7 21.8 12.5 5.6 9.6 4.6 9.6 7.3 11.2 1.5 1.9 13.5 2.2 0.8 1.8 1.1 7.2 19.1 4.7 9.2 4.1 2.8 9.0 5.8 1.9 6.0 5.4 12.2 7.2 11.2 5.9 3.2 6.5 10.7 6.5 7.6 3.1 9.3 17.7 11.7 10.4 9.2 4.6 9.0 5.0 3.6 6.2 10.1 5.7 3.9 4.0 5.1 19.4 4.9 4.0 8.6 8.9 22.6 9.8 9.5 11.5 9.9 3.7 6.7 3.2 9.8 8.4 5.2 7.1 7.1 4.7 5.6 6.4 5.8 4.5 7.0 9.1 4.4 10.2 7.4 10.2 10.4 5.6 6.6 8.2 1.0 2.0 0.8 1.3 2.2 1.2 1.2 1.0 1.8 1.9 1.5 1.6 0.7 13.5 0.8 1.7 1.5 0.6 1.1 12.6 11.5 18.7 13.3 11.2 6.4 12.3 8.4 11.4 12.5 6.0 7.2 2.2 5.1 6.6 7.7 2.8 0.0 6.7 3.4 7.0 2.0 4.2 0.0 4.3 20.8 3.1 3.4 0.0 2.8 4.7 3.0 5.1 3.5 4.4 6.7 0.0 3.5 3.1 5.9 48.6 4.9 10.4 1.7 3.6 3.9 1.5 3.1 2.9 4.6 1.4 5.1 6.5 3.6 24.5 11.7 6.4 4.2 3.2 4.3 5.2 DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" No No "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: AB_2682491, HPA062700: AB_2684838" "unprognostic (8.31e-2)" "unprognostic (2.34e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.29e-2)" "unprognostic (8.38e-2)" "prognostic unfavorable (5.63e-6)" "unprognostic (9.83e-2)" "unprognostic (2.21e-1)" "unprognostic (6.22e-2)" "unprognostic (4.47e-2)" "unprognostic (5.67e-2)" "unprognostic (8.57e-2)" "unprognostic (1.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (3.31e-1)" 10.4 7.3 9.7 6.9 14.6 13.9 9.8 9.7 14.3 12.2 23.2 14.8 10.7 9.9 19.7 13.9 13.9 12.5 9.2 16.9 9.0 5.8 10.4 7.5 8.7 12.6 8.2 6.7 13.9 6.5 12.1 13.5 8.4 10.9 13.3 14.3 12.4 10.4 12.6 12.5 11.1 12.4 14.7 9.9 8.4 13.4 12.5 9.4 12.1 8.5 7.6 11.2 15.9 11.8 4.6 6.7 2.0 4.9 5.8 8.2 4.4 7.3 4.5 12.0 4.9 4.6 6.0 8.5 4.4 7.9 10.2 7.8 21.2 7.2 8.5 7.9 8.4 7.9 11.7 8.3 13.0 10.1 2.1 4.1 11.3 10.1 12.0 5.5 13.1 5.9 7.0 8.4 9.0 8.4 6.3 4.5 14.5 11.4 4.9 5.4 6.0 21.4 10.1 6.9 13.4 9.9 10.5 17.5 6.8 3.7 8.5 10.6 8.3 12.1 7.3 11.2 7.8 10.0 10.8 4.4 14.7 8.1 5.8 9.2 4.9 6.4 8.8 8.6 6.0 7.6 0.0 4.9 2.0 5.3 4.5 5.2 4.6 4.5 5.6 6.7 4.3 8.2 4.3 1.0 5.8 3.8 2.4 2.8 4.4 9.7 14.6 9.7 14.3 9.0 5.8 8.2 6.7 10.9 9.4 0.0 3.0 0.8 1.2 0.5 5.8 4.8 5.1 4.0 4.5 1.8 3.9 3.1 1.7 2.5 2.9 2.4 3.3 0.0 1.0 2.0 2.4 2.1 8.1 5.5 4.3 4.8 5.2 5.5 3.7 0.4 5.8 3.1 3.3 2.8 6.2 2.6 1.7 2.9 6.0 1.7 4.6 0.0 2.3 1.7 10.0 1.8 2.5 1.7 4.4 1.0 DHX36 "DDX36, KIAA1488, MLEL1" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324497 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Early spermatids: 381.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035399 Approved Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA035399: AB_10670115" "unprognostic (8.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (3.50e-3)" "unprognostic (2.67e-2)" "unprognostic (3.22e-1)" "unprognostic (8.80e-3)" "unprognostic (1.03e-1)" "unprognostic (7.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (2.72e-1)" "unprognostic (5.09e-2)" "unprognostic (5.27e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" 16.3 14.0 11.5 14.1 27.5 12.6 15.7 19.0 21.3 17.9 14.7 10.3 12.4 10.7 20.4 10.6 14.5 14.3 13.7 23.9 13.4 12.7 16.7 17.1 14.6 17.0 12.2 15.0 20.0 13.7 34.0 36.2 16.4 20.1 15.7 12.2 9.3 15.5 20.5 53.4 14.7 14.3 15.1 13.7 18.9 13.4 28.3 11.3 24.3 20.4 13.4 17.1 20.7 15.6 6.3 5.9 3.1 5.7 4.8 6.9 1.1 27.0 18.5 25.1 14.4 11.9 16.7 12.5 17.7 17.8 20.2 24.1 18.8 21.8 26.2 28.7 15.5 18.6 17.5 23.6 15.0 31.8 25.1 15.6 19.0 15.9 10.7 20.2 26.4 16.7 18.8 12.7 21.6 26.6 11.0 17.3 16.3 17.8 15.1 18.6 13.2 21.8 5.8 33.4 14.4 17.8 22.7 21.2 37.8 14.5 19.2 23.6 25.1 18.4 19.6 25.7 17.9 20.1 13.5 19.5 21.2 13.4 19.8 35.3 28.4 18.3 37.9 17.1 13.9 22.4 1.9 2.7 3.1 6.9 2.8 4.4 4.7 6.1 4.7 2.3 6.3 5.8 6.0 1.1 4.8 5.7 5.9 5.4 1.1 11.5 27.5 19.0 21.3 13.4 12.7 12.2 15.0 20.1 11.3 53.6 78.8 70.6 103.5 82.5 148.4 52.9 61.1 50.9 96.7 57.6 121.7 106.5 33.2 60.5 381.7 74.4 34.4 23.3 54.3 56.1 68.1 82.0 99.5 71.8 54.2 146.2 88.2 62.6 59.6 255.9 102.4 80.8 50.6 65.9 47.0 93.9 58.1 42.4 114.2 44.2 123.0 77.6 80.4 174.2 142.0 72.6 309.5 99.1 47.7 105.0 DHX37 "DDX37, Dhr1, KIAA1517, MGC2695, MGC4322" ENSG00000150990 "DEAH-box helicase 37" Q8IY37 12 124946825-124989122 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047607 Approved Approved "Nuclear membrane" NA NA "Nuclear membrane" "HPA047607: AB_2680101" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.54e-10)" "unprognostic (2.38e-2)" "unprognostic (5.14e-2)" "unprognostic (2.90e-2)" "unprognostic (2.07e-1)" "unprognostic (3.16e-2)" "unprognostic (8.28e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (2.85e-2)" "unprognostic (2.73e-1)" 9.5 9.2 8.6 12.7 12.1 29.6 9.3 5.7 12.1 8.9 7.9 11.8 6.0 10.2 11.6 6.5 11.2 9.8 10.7 12.4 7.3 5.4 7.4 10.7 8.2 13.3 11.6 7.4 12.7 14.4 4.7 5.7 6.7 10.5 8.7 5.7 5.6 9.1 7.3 22.7 15.8 9.5 7.7 7.5 12.2 9.1 6.8 11.1 7.8 8.9 9.7 11.5 9.7 13.6 4.3 1.6 0.2 2.5 1.4 2.5 1.4 7.4 21.5 3.8 11.8 3.8 4.3 9.7 2.6 3.9 8.6 6.9 27.1 5.2 18.3 10.0 3.1 11.5 10.4 9.9 5.8 3.1 15.8 18.4 9.0 12.2 10.7 5.4 11.8 16.3 4.0 6.6 14.9 2.4 3.4 5.0 9.3 18.9 5.1 5.1 11.0 16.7 12.4 13.8 8.0 13.0 12.3 3.7 9.1 3.7 17.0 6.7 3.3 7.0 7.6 5.7 2.7 8.5 10.5 5.9 10.0 7.5 14.2 17.3 11.7 14.7 18.1 6.6 6.9 12.5 0.0 0.6 0.0 1.5 2.0 2.2 4.3 1.8 2.5 1.6 0.2 0.9 0.8 0.2 1.4 2.5 1.2 0.9 1.4 8.6 12.1 5.7 12.1 7.3 5.4 11.6 7.4 10.5 11.1 3.0 6.9 8.2 2.2 3.8 2.6 3.2 0.0 2.7 4.5 0.0 0.0 3.7 3.3 4.3 1.5 3.6 3.3 0.0 5.3 4.8 3.5 3.1 5.8 6.0 4.6 12.7 8.6 1.8 6.9 1.5 4.9 4.5 0.0 6.4 6.7 2.0 7.2 0.0 2.5 3.9 1.8 6.5 2.7 1.4 5.6 3.4 2.4 4.4 7.3 2.8 DHX38 "DDX38, hPrp16, KIAA0224, PRP16, PRPF16" ENSG00000140829 "DEAH-box helicase 38" Q92620 16 72093562-72112912 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041347, HPA041604" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA041347: AB_10796571, HPA041604: AB_2677577" "unprognostic (2.38e-1)" "unprognostic (1.89e-1)" "unprognostic (1.24e-2)" "unprognostic (3.25e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (6.32e-3)" "unprognostic (8.50e-3)" "unprognostic (6.97e-2)" "unprognostic (1.45e-1)" "unprognostic (7.92e-2)" "unprognostic (1.28e-3)" "unprognostic (4.20e-3)" "unprognostic (2.68e-1)" "unprognostic (9.46e-2)" "unprognostic (2.40e-1)" "unprognostic (2.40e-2)" 21.8 16.5 21.1 22.2 25.0 35.1 20.5 36.0 29.4 18.6 19.5 23.5 19.4 20.1 24.1 13.5 21.1 19.9 18.1 19.2 24.1 13.7 17.3 20.8 20.6 26.1 24.1 20.7 29.0 17.3 36.6 18.7 19.3 20.9 18.3 17.2 17.9 20.4 16.4 33.0 27.2 23.0 23.5 22.5 27.3 19.4 17.5 27.8 24.6 20.8 23.2 23.1 20.5 21.4 10.4 8.1 8.3 10.6 11.8 14.9 6.3 14.5 21.7 15.7 8.8 13.7 10.6 20.7 13.2 12.9 19.7 15.2 26.2 14.6 19.4 11.8 19.8 11.0 19.2 18.2 18.1 15.3 9.7 19.6 14.9 18.4 35.7 12.8 17.5 27.0 14.7 16.7 26.5 19.2 10.5 17.0 14.1 22.0 9.2 12.1 44.8 16.7 19.9 19.8 9.3 12.5 21.6 10.9 19.2 9.5 13.9 14.2 15.6 16.9 8.1 9.3 9.5 14.7 14.6 19.2 19.0 16.9 13.8 14.3 22.8 18.0 37.3 17.9 12.2 14.8 7.4 7.9 8.3 14.9 10.6 13.7 10.4 9.3 10.7 8.1 8.2 10.4 10.8 8.2 11.8 6.6 7.4 10.9 6.3 21.1 25.0 36.0 29.4 24.1 13.7 24.1 20.7 20.9 27.8 23.8 30.1 24.7 9.7 10.9 28.0 7.5 15.3 21.4 30.7 14.0 15.7 11.7 0.0 11.7 6.6 18.0 21.3 0.0 17.7 11.6 13.5 9.4 40.6 11.6 12.9 28.6 29.3 14.1 13.9 9.1 26.7 18.7 8.5 14.4 20.2 18.0 18.2 15.8 23.7 6.5 35.4 19.4 13.3 22.7 15.8 11.2 17.0 23.5 17.1 9.9 DHX40 "ARG147, DDX40, FLJ22060, PAD" ENSG00000108406 "DEAH-box helicase 40" Q8IX18 17 59565525-59608345 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044350 Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA044350: AB_10960560" "unprognostic (1.58e-2)" "unprognostic (3.10e-1)" "prognostic favorable (4.05e-5)" "unprognostic (4.09e-2)" "unprognostic (5.23e-2)" "unprognostic (2.84e-1)" "unprognostic (4.57e-3)" "unprognostic (7.53e-3)" "unprognostic (2.86e-2)" "unprognostic (1.80e-1)" "unprognostic (7.23e-2)" "unprognostic (3.08e-1)" "unprognostic (9.48e-3)" "unprognostic (2.22e-1)" "unprognostic (1.25e-2)" "unprognostic (1.11e-1)" "unprognostic (3.10e-1)" 22.4 24.2 16.2 14.0 18.1 19.5 24.8 21.7 18.4 21.4 16.5 17.5 23.7 12.8 27.0 25.0 19.3 24.8 16.5 19.8 17.1 19.5 29.5 13.1 16.7 16.8 17.9 14.7 29.7 21.0 51.3 45.8 21.9 19.0 21.6 15.4 13.7 19.3 27.8 20.4 21.3 12.3 18.9 19.9 15.6 17.2 28.4 16.8 26.1 28.2 16.0 15.5 26.0 19.7 5.4 6.9 18.8 6.6 4.2 10.6 6.1 11.7 21.6 27.5 17.8 16.8 17.4 15.2 10.6 20.4 16.3 18.5 8.4 11.7 15.4 30.0 15.3 17.3 8.7 19.6 15.0 25.3 12.2 28.6 14.1 16.2 9.4 13.1 16.9 6.6 13.3 13.8 13.7 13.4 26.8 17.3 15.2 11.8 14.3 11.0 21.3 20.8 10.5 10.4 14.5 15.8 20.0 19.3 16.8 16.4 9.5 19.5 48.2 19.2 7.6 19.5 14.0 24.7 10.0 14.1 19.7 24.5 7.0 10.4 17.7 19.4 9.9 23.1 11.8 13.4 8.5 6.6 10.5 8.1 6.5 10.6 5.1 5.9 5.8 6.9 5.4 5.9 6.9 18.8 4.2 4.4 3.5 6.0 6.1 16.2 18.1 21.7 18.4 17.1 19.5 17.9 14.7 19.0 16.8 8.9 18.1 9.6 9.0 17.2 11.9 20.3 22.9 61.6 30.7 45.4 17.7 6.9 10.0 15.3 32.5 20.4 12.2 0.0 14.6 7.3 13.9 12.6 3.5 23.8 7.9 47.7 17.7 24.5 16.1 12.2 23.3 12.4 18.6 2.8 17.7 18.8 12.6 11.5 25.1 25.0 13.4 32.3 13.2 56.5 50.9 19.3 10.5 16.6 15.8 9.2 DHX57 DDX57 ENSG00000163214 "DExH-box helicase 57" Q6P158 2 38797729-38875934 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 16 "Early spermatids: 120.8;Late spermatids: 273.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036160 Uncertain Approved "Nucleoli,Intermediate filaments,Microtubules,Cytosol" NA NA "Intermediate filaments, Microtubules" "Nucleoli, Cytosol" "HPA036160: AB_10670711" "unprognostic (6.78e-2)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (2.03e-3)" "unprognostic (3.25e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.75e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (3.88e-2)" "unprognostic (7.03e-3)" "unprognostic (1.77e-1)" 9.6 11.2 9.7 8.5 16.7 7.0 10.4 11.9 16.4 14.1 9.4 9.9 9.8 4.2 13.9 17.1 8.4 11.2 9.5 9.3 9.6 11.0 11.2 7.2 7.9 9.2 8.9 9.5 13.2 9.5 18.9 17.9 11.2 13.1 10.5 9.2 11.6 7.8 14.2 11.5 11.1 6.9 11.8 7.7 9.9 7.9 27.7 8.3 13.9 11.8 8.1 11.1 10.5 8.3 7.1 5.2 1.7 10.1 3.3 6.0 4.2 16.9 13.6 15.3 11.5 10.1 12.4 12.5 11.8 11.7 11.2 11.1 10.9 5.2 5.0 11.9 12.0 12.7 8.8 17.2 13.1 18.5 20.5 12.7 9.7 9.2 14.9 9.1 10.2 5.6 11.8 7.9 14.5 9.1 7.9 14.9 3.7 12.4 7.1 12.1 12.4 10.2 9.4 19.0 7.3 8.1 5.1 20.2 9.8 10.3 6.5 12.6 18.6 11.8 12.2 13.8 11.2 8.6 5.6 11.5 11.2 13.0 8.5 12.7 7.4 8.3 2.1 8.7 7.1 7.4 1.7 10.1 1.7 4.5 6.9 6.0 5.7 4.0 3.5 5.2 7.1 4.8 3.0 0.5 3.3 8.0 1.7 3.3 4.2 9.7 16.7 11.9 16.4 9.6 11.0 8.9 9.5 13.1 8.3 3.0 7.5 8.2 2.2 2.4 23.0 5.9 5.1 28.1 13.6 22.7 53.0 6.0 0.0 6.9 120.8 4.3 1.6 23.3 6.4 5.8 5.6 1.6 10.4 5.7 6.1 17.5 11.3 9.2 13.6 273.7 14.7 9.5 1.7 5.4 5.5 11.2 6.9 3.5 13.1 4.9 28.3 0.0 3.9 15.2 6.4 2.3 2.4 6.9 5.1 1.3 DHX58 "D11LGP2, LGP2" ENSG00000108771 "DExH-box helicase 58" Q96C10 17 42101404-42112733 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "monocytes: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 24.6;BJ hTERT+ SV40 Large T+ RasG12V: 28.8;SK-MEL-30: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018670, HPA019570" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Golgi apparatus, Cytosol" Nucleoplasm "HPA018670: AB_1847665, HPA019570: AB_1847666" "prognostic favorable (3.45e-4)" "unprognostic (1.03e-2)" "unprognostic (3.56e-3)" "unprognostic (1.54e-2)" "unprognostic (2.45e-2)" "unprognostic (4.82e-2)" "unprognostic (2.05e-3)" "unprognostic (5.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.15e-1)" "unprognostic (6.02e-2)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (8.65e-2)" "unprognostic (8.01e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 12.7 16.3 6.7 15.3 7.8 11.1 9.8 2.8 8.4 7.9 9.8 9.6 15.0 8.2 9.6 16.2 8.7 12.0 12.6 5.3 6.5 5.3 11.0 20.9 21.7 14.4 5.9 9.0 12.9 7.4 4.3 9.6 7.0 8.2 10.6 5.0 13.4 18.0 17.1 6.9 7.8 10.5 9.2 7.9 17.1 9.1 10.7 5.1 17.2 7.5 5.6 12.9 10.9 7.6 6.4 7.6 8.6 12.0 7.6 7.1 5.9 1.2 0.0 0.0 0.7 6.2 5.4 0.2 1.7 11.9 24.6 28.8 0.1 7.7 0.1 1.8 2.8 5.6 1.0 0.1 1.9 0.9 4.8 0.1 2.0 1.1 0.4 7.0 1.8 4.6 8.7 3.2 2.1 2.1 4.3 2.9 12.5 0.0 6.8 1.3 0.0 11.0 2.3 0.2 0.3 0.0 4.0 0.0 0.5 2.7 4.5 0.2 0.0 0.8 3.1 14.0 0.0 4.2 1.9 1.2 1.2 0.0 0.4 0.6 2.3 1.9 0.1 2.5 1.7 1.3 3.1 9.9 8.6 4.5 12.0 6.5 6.4 6.4 4.0 7.6 4.9 7.1 5.3 4.0 7.6 10.5 2.5 5.5 5.9 6.7 7.8 2.8 8.4 6.5 5.3 5.9 9.0 8.2 5.1 8.9 4.3 2.7 4.8 1.3 0.6 0.8 5.1 8.1 6.8 7.0 0.0 2.8 1.7 4.9 5.4 4.5 2.4 0.0 6.0 2.8 2.8 5.0 1.1 10.5 8.8 0.0 0.0 5.5 6.0 8.3 8.1 5.0 3.3 65.9 2.8 2.0 5.1 4.9 8.5 3.8 0.6 0.0 2.3 9.6 0.7 1.4 0.7 7.7 1.6 1.8 DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43544463 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA Nucleoplasm "Nuclear bodies" "HPA049285: AB_2680698" "unprognostic (2.99e-1)" "unprognostic (4.42e-2)" "unprognostic (5.64e-2)" "unprognostic (9.02e-2)" "unprognostic (1.25e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-3)" "unprognostic (9.43e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-2)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (4.04e-1)" "unprognostic (5.08e-3)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" 21.9 18.6 17.5 17.0 22.9 47.8 22.3 21.6 29.8 20.3 21.0 25.3 17.2 17.1 26.1 28.4 26.6 17.9 16.7 18.5 18.1 18.7 18.5 20.1 19.8 21.0 20.8 19.7 19.5 17.4 35.4 23.0 21.7 22.7 22.1 24.6 20.1 21.7 21.7 25.2 32.9 22.0 24.6 19.2 27.3 19.5 34.6 20.6 40.8 20.5 17.8 28.9 19.4 22.6 11.5 16.3 23.3 20.4 9.5 14.9 9.8 12.5 35.7 19.4 24.1 19.4 19.8 10.7 13.2 27.9 29.2 28.1 16.2 12.8 17.4 12.3 25.9 21.0 17.0 29.1 23.2 34.3 18.2 23.0 14.7 27.2 25.1 16.6 25.5 22.4 9.9 19.7 24.0 26.4 14.1 25.9 22.9 16.3 17.2 22.6 13.7 32.3 22.7 15.8 15.3 13.7 19.7 37.0 17.9 19.8 26.4 16.8 25.3 14.8 8.5 11.8 24.4 19.8 25.2 17.6 22.8 12.4 16.4 19.7 12.9 15.3 19.7 18.9 15.9 18.2 23.3 15.2 17.2 13.7 20.4 13.6 11.5 11.4 14.9 16.3 10.6 11.2 10.9 19.2 9.5 19.6 8.4 11.7 9.8 17.5 22.9 21.6 29.8 18.1 18.7 20.8 19.7 22.7 20.6 6.0 12.9 15.2 5.8 10.5 15.7 11.9 12.7 12.0 22.7 21.0 17.7 7.9 11.6 14.1 16.1 13.5 8.9 0.0 15.3 7.0 11.1 7.5 13.9 13.1 9.6 6.4 25.6 12.9 13.3 8.1 11.5 12.0 16.9 17.2 13.1 10.1 15.6 11.5 10.3 10.1 18.6 19.4 11.1 24.9 14.5 11.7 17.7 16.0 10.2 14.4 DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839369-182887751 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011819, HPA028050, HPA055684" Supported Supported Nucleoplasm,Nucleoli NA NA 97000 Nucleoplasm Nucleoli "CAB011819: AB_777725, HPA028050: AB_10603564, HPA055684: AB_2682885" "unprognostic (8.14e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (9.98e-2)" "prognostic unfavorable (6.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.88e-2)" "unprognostic (5.53e-2)" "unprognostic (7.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-1)" 30.2 25.9 25.7 28.5 28.6 68.9 32.9 42.5 33.1 31.9 24.5 23.3 25.2 19.8 38.2 24.2 27.7 30.6 19.7 22.9 24.4 22.6 36.2 31.4 27.8 32.0 34.2 23.1 37.5 24.9 51.8 35.8 28.5 28.0 25.7 30.1 21.1 28.2 29.4 27.6 26.6 27.0 31.6 25.3 32.8 26.5 29.4 37.4 68.3 30.1 31.6 41.2 32.4 31.9 16.8 22.9 12.0 17.4 14.7 21.9 15.0 35.7 35.0 50.3 27.6 26.3 20.4 49.7 31.7 29.1 46.1 31.3 39.1 27.6 57.4 31.0 28.4 27.6 31.0 76.3 34.3 51.7 23.3 37.9 38.2 28.7 26.4 14.8 55.3 26.2 18.1 17.3 45.2 12.3 20.9 36.0 29.5 60.0 20.6 36.9 31.4 55.9 13.6 63.7 38.5 21.6 51.0 46.9 32.8 29.8 41.6 36.3 41.6 44.9 28.4 18.5 44.2 33.3 31.3 28.1 28.6 32.0 29.0 42.9 21.7 35.4 68.1 18.0 30.4 38.8 5.6 16.0 12.0 19.2 17.4 21.9 16.8 16.8 17.6 22.9 14.6 18.4 19.9 6.5 14.7 14.3 11.1 15.4 15.0 25.7 28.6 42.5 33.1 24.4 22.6 34.2 23.1 28.0 37.4 38.7 64.9 41.5 53.0 47.7 55.9 37.2 35.7 72.3 69.4 48.8 49.1 40.4 16.6 39.6 17.1 44.9 31.7 0.0 43.7 37.7 35.9 40.6 42.8 24.3 35.2 27.0 51.6 38.1 37.7 32.0 55.8 34.4 28.7 27.1 33.8 42.7 42.4 25.9 44.2 33.5 72.8 38.8 45.7 63.0 65.2 41.3 41.4 32.4 45.7 48.7 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol NA NA Cytosol "CAB068185: AB_2665650, HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 23.2 12.5 18.4 22.4 33.3 20.5 23.2 28.5 29.9 19.0 18.1 31.4 22.4 13.0 20.8 20.6 23.4 18.5 16.2 15.3 22.0 14.1 19.5 23.6 22.4 20.3 29.7 19.6 23.8 19.8 26.9 30.9 29.9 23.2 20.3 19.7 14.5 19.5 18.9 28.0 20.7 17.3 19.0 26.8 20.7 17.1 20.6 32.0 17.0 23.8 14.7 20.3 20.7 24.1 2.5 1.8 10.7 7.2 1.2 3.3 1.0 12.9 13.6 25.4 9.4 6.6 9.9 20.1 10.7 6.5 6.8 8.3 17.2 10.0 14.7 11.6 10.0 7.1 15.3 20.1 10.1 14.4 22.7 9.0 22.2 7.4 12.4 6.6 13.6 13.6 9.2 8.3 9.2 14.1 5.9 10.2 11.6 9.3 13.1 11.5 18.2 15.2 9.0 7.2 9.1 6.7 12.1 20.8 8.1 9.1 20.7 21.1 11.9 10.8 11.1 12.2 14.1 12.6 10.0 10.1 5.3 10.5 10.2 12.0 14.9 21.3 20.8 5.5 11.0 9.4 3.1 3.0 1.2 1.6 3.1 3.3 1.9 1.5 1.2 1.8 2.5 1.5 1.3 10.7 1.2 7.2 1.6 1.6 1.0 18.4 33.3 28.5 29.9 22.0 14.1 29.7 19.6 23.2 32.0 50.6 47.2 32.6 39.2 24.4 99.7 34.3 38.2 32.1 51.2 43.6 53.0 39.4 5.0 30.3 19.8 39.1 29.6 23.3 19.9 20.7 34.6 55.9 11.5 50.5 41.7 101.7 44.3 41.1 94.2 12.0 50.3 46.8 21.9 19.0 30.6 35.0 28.4 23.0 49.5 22.6 68.5 32.3 35.0 34.9 52.5 24.1 21.5 23.0 31.6 49.7 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease mutation, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 49.1" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 70.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.5" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.5" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No No Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.6 1.2 2.0 13.7 2.4 7.0 3.0 6.2 3.8 1.6 4.5 1.1 0.8 3.5 3.0 1.8 3.2 1.0 2.4 2.0 2.5 2.2 3.4 6.2 3.3 8.4 2.9 5.0 1.9 2.4 1.1 2.3 4.0 1.7 3.0 5.0 0.9 2.3 0.8 2.3 2.9 5.2 1.9 3.0 5.2 2.6 7.0 1.4 49.1 1.5 5.1 10.8 2.3 2.0 0.4 0.1 0.9 0.1 5.5 0.6 0.1 13.9 7.2 16.5 11.6 1.9 1.3 11.6 6.9 5.8 9.9 12.2 17.2 9.1 14.3 2.6 2.1 3.8 8.6 9.4 3.6 12.0 8.8 7.1 8.7 4.5 6.6 0.5 14.9 9.4 1.0 1.5 7.0 2.1 2.5 4.4 9.5 12.7 13.0 5.7 4.9 23.0 10.8 11.6 5.9 13.6 18.0 11.4 4.6 4.2 6.5 7.5 9.0 9.5 12.1 2.3 12.2 9.3 6.3 1.8 3.8 11.9 4.8 13.1 6.6 7.4 21.4 3.2 14.3 5.0 0.0 0.0 0.9 0.2 0.0 0.2 0.4 0.2 0.6 0.1 0.4 0.3 0.3 0.1 5.5 0.1 0.0 0.4 0.1 2.0 2.4 6.2 3.8 2.5 2.2 2.9 5.0 1.7 1.4 6.0 0.6 0.0 0.7 2.1 2.2 7.3 2.5 0.0 1.2 1.8 5.9 2.0 0.0 0.5 1.6 0.7 1.3 70.0 0.8 3.8 1.9 3.2 0.0 4.4 1.8 0.0 1.2 1.3 2.2 3.1 0.6 0.0 0.0 0.0 1.3 0.2 0.7 0.0 0.7 0.4 3.6 0.0 1.0 5.0 14.2 1.5 1.0 1.5 2.3 0.9 DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 91.4" "Cell type enhanced" "Detected in many" 11 "Bipolar cells: 29.6;Cardiomyocytes: 26.1;Erythroid cells: 23.3;Horizontal cells: 49.3;Rod photoreceptor cells: 21.6" "Cancer enhanced" "Detected in many" "glioma: 5.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "gdT-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 21.2;HEL: 56.7;K-562: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: AB_10611957, HPA054917: AB_2682641" "unprognostic (6.99e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-1)" "unprognostic (7.94e-7)" "unprognostic (1.59e-1)" "unprognostic (7.61e-3)" "unprognostic (1.87e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (4.14e-1)" "unprognostic (4.22e-3)" "unprognostic (1.53e-1)" "prognostic favorable (2.81e-4)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (8.67e-3)" 2.1 12.1 18.6 2.2 28.5 5.0 2.0 24.2 91.4 2.2 2.8 26.9 0.0 2.3 1.9 1.8 1.7 2.4 2.3 9.0 25.0 26.7 8.5 1.6 2.7 1.6 28.8 23.8 1.9 3.4 2.1 7.5 8.0 40.5 2.5 3.0 2.2 1.7 2.1 1.6 2.1 2.3 2.2 28.7 3.2 2.9 3.2 21.1 0.0 3.0 0.0 1.7 1.8 0.6 0.5 0.5 0.0 0.0 0.6 1.5 0.3 3.5 1.0 0.0 1.6 0.8 0.2 8.4 7.1 11.6 11.7 11.5 0.9 0.1 3.4 0.6 2.9 2.9 0.9 5.1 1.1 9.2 21.2 2.4 56.7 1.9 0.2 0.0 1.9 1.4 1.0 0.8 1.1 5.0 2.2 0.2 2.8 22.0 0.4 2.4 0.6 0.7 0.0 2.3 0.0 0.8 0.0 1.7 0.1 8.9 0.0 14.2 9.7 4.1 5.6 1.9 14.1 2.7 0.1 2.2 1.7 1.2 0.2 2.0 2.1 1.4 1.0 4.8 1.4 2.9 0.0 0.0 0.0 1.5 0.0 0.1 0.5 0.5 0.9 0.0 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.3 18.6 28.5 24.2 37.4 25.0 26.7 28.8 23.8 40.5 21.1 0.0 0.3 0.0 0.2 1.1 29.6 26.1 0.0 0.0 0.0 0.0 13.7 4.8 1.7 0.8 1.8 0.7 0.0 23.3 0.6 1.9 1.7 1.3 0.0 0.0 1.1 49.3 6.9 0.0 0.0 1.4 0.0 0.8 6.8 1.8 1.3 3.1 0.4 0.0 0.0 5.9 21.6 0.0 2.3 1.0 2.3 0.3 6.2 0.0 0.5 0.1 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 26.7" "Cell type enhanced" "Detected in many" 5 "Distal tubular cells: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 160000 Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 1.5 1.4 1.5 2.6 1.6 1.7 1.5 3.8 2.5 2.2 12.2 1.8 1.5 14.9 1.5 2.2 3.4 1.2 2.5 1.5 1.5 1.2 11.4 1.5 1.5 4.4 1.5 1.5 2.0 13.7 1.6 12.2 1.9 3.1 5.1 2.1 1.5 3.3 1.5 1.5 3.9 26.7 1.5 1.5 2.3 6.0 2.7 1.5 1.5 1.6 2.6 3.8 1.9 2.3 4.5 2.2 9.2 2.0 1.9 3.4 1.0 2.5 5.8 10.2 5.3 3.0 2.6 4.8 4.0 0.7 3.3 4.8 6.9 6.1 10.7 3.3 0.6 7.0 4.2 3.6 1.1 3.5 4.6 5.6 3.7 8.6 4.5 1.5 2.6 8.7 2.1 4.3 4.4 1.1 5.2 2.2 9.0 9.3 4.7 2.8 10.4 5.3 11.5 6.2 7.4 3.1 12.6 4.6 5.2 2.8 2.2 7.2 6.7 3.0 9.2 1.7 5.3 9.1 6.6 3.0 6.1 4.5 3.8 2.3 4.3 6.1 18.5 1.7 4.9 5.8 4.3 2.0 5.3 3.0 1.3 1.9 2.5 2.3 2.4 1.0 4.5 2.7 3.4 9.2 1.9 1.2 2.2 2.4 1.0 1.5 1.6 3.8 2.5 1.5 1.2 1.5 1.5 3.1 1.5 8.9 10.1 2.4 8.5 2.4 27.4 4.8 5.1 9.4 11.4 15.7 21.6 6.6 48.0 4.5 16.1 4.5 12.7 0.0 9.7 3.3 5.1 9.8 2.3 1.5 3.2 23.8 13.7 4.9 2.7 34.9 7.8 3.8 1.7 11.8 11.3 12.8 4.3 11.2 7.4 1.4 18.3 0.0 4.2 15.1 17.5 3.3 5.1 10.5 15.3 5.3 DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875211-12881468 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Hofbauer cells: 210.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" NA NA 720000 "HPA066185: AB_2685632" "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" 18.7 22.1 13.1 17.0 13.4 4.8 16.9 6.0 12.9 21.2 22.8 15.9 15.8 14.6 19.6 27.9 22.7 17.0 20.6 18.0 11.5 9.4 17.1 40.7 37.4 34.5 14.9 7.7 20.0 33.3 21.2 18.9 28.1 11.6 18.4 13.5 22.6 24.9 18.0 16.6 20.5 15.9 14.6 13.1 24.1 20.9 9.4 11.0 20.0 36.4 13.6 26.9 20.5 14.8 11.8 10.3 20.1 37.8 21.9 26.6 19.6 16.5 8.4 0.7 22.7 25.0 13.1 14.8 8.5 23.7 8.7 22.2 0.7 11.9 7.9 24.8 15.3 19.6 19.4 8.9 8.9 4.9 21.9 9.8 3.5 10.0 4.3 20.2 7.1 32.9 12.8 21.2 6.9 10.8 22.9 13.0 11.2 3.1 32.8 5.8 21.5 6.9 3.9 1.4 18.1 15.1 4.4 4.0 17.4 9.5 7.0 4.8 7.4 12.8 18.6 31.6 3.6 27.5 6.5 7.8 18.1 5.7 18.1 7.8 35.9 36.8 9.8 30.2 6.5 9.2 20.1 25.5 3.6 22.3 33.8 18.4 11.6 19.6 23.6 5.0 11.8 17.6 19.2 14.8 21.9 37.8 10.3 26.6 19.6 13.1 13.4 6.0 12.9 11.5 9.4 14.9 7.7 11.6 11.0 23.8 19.0 35.0 21.7 12.9 7.3 8.4 25.5 32.1 13.6 34.9 3.9 50.1 3.3 55.2 0.4 15.7 14.7 0.0 51.5 79.5 24.6 17.3 21.9 22.5 210.0 4.8 15.7 19.6 67.4 1.5 29.7 32.9 43.9 34.3 11.5 38.2 37.2 77.0 31.5 6.1 2.4 12.9 13.7 0.5 5.1 10.8 40.2 27.4 24.3 12.9 DNASE2B DLAD ENSG00000137976 "Deoxyribonuclease 2 beta" Q8WZ79 1 84398532-84415018 "Enzymes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "salivary gland: 98.7" "Cell type enhanced" "Detected in some" 17 "Ciliated cells: 1.4;Early spermatids: 1.6;Glandular cells: 2.3;Hofbauer cells: 5.7;Late spermatids: 2.4;Paneth cells: 1.7" "Cancer enhanced" "Detected in some" "prostate cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HL-60: 1.0;HUVEC TERT2: 2.1;SK-MEL-30: 2.6;U-266/70: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "unprognostic (2.24e-1)" "unprognostic (3.57e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-2)" "unprognostic (9.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (3.82e-5)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" 16.2 0.1 0.2 0.1 2.2 0.1 0.3 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.6 0.1 0.2 13.0 1.2 0.3 0.0 0.3 0.4 0.0 0.4 0.1 0.2 2.9 0.3 0.0 98.7 0.1 1.8 0.0 0.1 0.1 1.7 0.5 0.6 0.3 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.6 0.2 0.0 0.0 0.0 0.0 0.2 0.4 0.0 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.3 0.3 0.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 5.7 0.0 1.2 0.0 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 133.5" "Group enriched" "Detected in many" 10 "Bipolar cells: 113.1;Cone photoreceptor cells: 84.4;Horizontal cells: 47.7;Rod photoreceptor cells: 70.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 49.8;U-87 MG: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910, HPA061801" Enhanced Supported Nucleoplasm NA NA 440000 Nucleoplasm "CAB005920: , HPA049910: AB_2680948, HPA061801: AB_2797266" "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" 5.9 6.1 31.5 3.3 36.9 2.3 4.6 57.7 133.5 11.7 3.0 2.5 0.0 2.4 4.6 2.7 3.3 6.3 9.0 2.7 33.4 24.0 2.9 1.8 2.5 2.5 18.3 33.0 1.6 4.7 3.2 5.5 2.7 33.0 2.9 2.9 4.3 2.6 3.1 2.3 4.6 3.3 4.4 5.1 1.6 2.6 4.0 1.8 0.0 1.9 0.4 2.3 3.6 3.7 0.3 0.4 0.5 0.3 0.0 0.3 0.7 3.3 49.8 4.5 1.1 1.4 15.2 0.2 3.1 7.5 6.3 2.6 0.6 1.0 0.0 4.3 6.5 0.2 6.0 0.7 0.3 3.5 0.0 4.8 3.1 7.1 0.2 1.0 0.4 2.2 4.0 0.1 4.9 0.0 6.1 0.0 2.9 1.1 0.2 0.0 1.4 0.2 1.0 4.8 0.8 9.1 5.9 0.1 1.5 0.9 0.0 6.5 10.9 10.6 0.3 0.4 0.6 0.1 4.3 0.2 0.2 14.4 14.5 6.3 0.4 0.1 0.3 19.0 0.1 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.4 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.7 31.5 36.9 57.7 71.8 33.4 24.0 18.3 33.0 33.0 1.8 0.0 0.0 0.0 1.6 7.0 113.1 2.0 7.6 1.4 1.2 0.0 84.4 0.2 1.7 0.7 0.5 1.5 0.6 0.0 0.7 0.2 3.9 0.7 1.1 0.5 8.0 47.7 0.0 0.0 0.8 0.4 2.6 1.9 3.3 1.0 0.1 8.1 1.0 2.9 1.4 3.4 70.6 0.0 4.1 0.3 1.3 6.6 0.7 0.7 0.6 0.5 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Enhanced Vesicles,Cytosol NA NA 10000000 Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: AB_2676443" "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 15.4 16.2 24.9 14.8 34.4 22.3 14.3 40.5 37.8 13.0 14.5 12.4 14.9 12.3 16.5 16.5 19.8 13.3 11.9 25.4 26.1 28.1 19.4 12.8 11.2 13.8 23.4 23.2 14.1 9.8 28.7 18.8 16.0 27.9 19.3 16.0 12.1 11.1 21.1 25.6 11.8 11.0 21.7 21.7 11.6 12.2 23.1 14.9 13.4 15.2 17.4 15.8 16.9 12.2 5.9 17.0 5.0 14.6 7.2 7.9 7.1 21.3 21.4 22.4 23.0 18.2 18.6 43.4 24.1 18.5 22.8 21.1 29.9 16.4 28.8 16.9 21.7 23.3 19.3 23.6 27.7 27.4 15.2 19.2 32.8 20.6 16.5 15.0 23.2 17.3 16.8 14.1 24.0 24.8 21.9 27.5 15.0 23.6 12.5 26.0 8.3 9.2 19.5 47.3 13.6 10.5 15.7 42.2 19.7 19.2 29.5 19.6 20.1 25.6 17.6 18.7 52.0 20.2 15.9 24.8 19.4 19.6 45.5 22.3 8.8 23.7 30.0 18.9 15.6 14.7 5.0 9.7 3.1 5.6 14.6 6.8 5.9 6.0 5.9 17.0 5.2 7.3 7.9 1.7 7.2 13.6 5.4 6.1 7.1 24.9 34.4 40.5 37.8 26.1 28.1 23.4 23.2 27.9 14.9 35.7 38.5 29.4 27.6 26.7 71.7 69.9 20.4 26.8 40.9 24.4 123.7 25.6 26.6 27.7 51.2 34.9 15.4 0.0 21.8 50.9 25.9 26.7 49.7 14.8 27.0 119.2 29.3 25.2 33.3 58.7 24.7 32.4 13.5 44.1 18.9 66.0 35.1 14.0 28.7 19.5 150.0 19.4 37.0 66.2 50.8 24.1 30.1 27.7 23.8 31.5 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 500000 "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 23.8 32.6 18.5 29.3 31.2 53.4 20.4 25.7 29.7 20.1 51.4 57.5 46.0 32.1 20.4 16.8 29.9 19.7 27.0 35.0 20.8 18.0 38.5 25.1 39.2 28.2 48.3 18.0 17.9 32.2 19.5 20.0 32.3 32.2 24.0 42.5 24.5 24.7 37.7 46.6 40.6 50.8 18.6 43.1 37.6 48.2 23.3 36.4 39.1 23.5 21.1 41.5 35.7 31.5 3.4 11.1 8.6 9.8 10.1 5.8 4.6 35.0 29.0 21.3 16.9 22.0 21.5 27.3 23.5 22.3 34.8 29.6 28.9 23.2 25.5 42.3 25.3 16.6 30.8 29.0 25.5 29.2 31.2 23.0 48.9 25.9 32.3 27.1 26.8 46.4 22.1 19.7 26.6 25.1 21.2 33.8 26.3 39.3 43.9 21.4 42.5 37.3 25.6 24.2 41.6 35.2 37.9 23.1 28.7 22.9 52.9 30.7 20.1 26.8 23.0 16.8 24.8 18.4 32.0 30.6 38.3 13.0 53.7 31.0 36.4 37.1 23.5 28.6 41.1 18.9 3.0 4.5 8.6 5.6 8.2 5.1 3.4 4.2 5.8 5.3 3.1 2.4 4.1 8.5 10.1 9.8 11.1 4.8 4.6 18.5 31.2 25.7 29.7 20.8 18.0 48.3 18.0 32.2 36.4 29.8 21.1 33.5 15.2 20.6 26.5 23.8 15.3 5.3 18.2 48.8 21.6 21.9 43.1 30.7 37.5 27.5 130.4 0.0 27.6 96.1 18.2 17.4 18.5 18.7 42.3 41.3 20.7 20.3 22.9 75.8 15.5 40.5 18.6 50.5 92.3 16.0 35.8 87.7 26.2 31.5 27.7 25.8 19.8 8.0 13.3 27.6 26.5 39.9 56.9 19.7 DNM3 KIAA0820 ENSG00000197959 "Dynamin 3" Q9UQ16 1 171841498-172418466 "Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell type enhanced" "Detected in many" 9 "Bipolar cells: 19.5;Cone photoreceptor cells: 27.5;Endothelial cells: 14.6;Rod photoreceptor cells: 28.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 18.2;HMC-1: 8.5;RPTEC TERT1: 15.7;U-251 MG: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064121 Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA064121: AB_2685193" "unprognostic (8.21e-2)" "unprognostic (6.80e-3)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (8.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.52e-3)" "unprognostic (6.46e-2)" "unprognostic (5.52e-2)" "unprognostic (2.96e-2)" "unprognostic (2.45e-2)" "unprognostic (3.37e-1)" "unprognostic (6.10e-4)" "unprognostic (1.60e-3)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (2.70e-3)" 5.0 19.3 14.1 2.3 28.3 2.6 3.4 41.4 39.7 6.8 2.7 26.8 0.0 1.9 5.9 3.1 3.0 6.0 5.1 3.0 14.3 16.3 5.8 1.4 7.5 2.5 19.6 17.7 4.6 2.6 3.5 10.3 1.6 47.3 3.6 2.7 2.9 3.7 3.6 2.5 4.0 2.4 5.7 16.4 3.6 5.3 5.4 22.1 0.0 3.4 0.0 2.2 4.3 3.6 0.7 0.7 1.1 0.4 1.0 4.0 3.8 0.6 2.0 1.6 0.3 1.2 0.8 0.0 0.4 1.0 0.8 1.0 0.0 3.0 0.0 6.3 0.9 1.0 0.2 1.2 2.3 0.7 0.8 2.4 18.2 3.0 0.0 0.1 0.3 8.5 0.6 0.4 1.0 0.5 0.9 0.4 1.6 0.0 0.3 0.3 0.0 1.1 0.1 4.7 7.5 1.4 1.2 8.2 0.0 15.7 0.1 3.2 0.6 2.2 0.6 0.2 0.6 0.0 0.7 0.2 2.3 3.2 1.9 11.3 3.1 0.5 0.1 2.2 0.9 0.8 0.0 0.4 0.0 0.7 0.0 0.9 0.7 1.0 0.5 0.7 0.0 1.2 1.5 1.1 1.0 0.3 0.0 4.0 3.8 14.1 28.3 41.4 31.6 14.3 16.3 19.6 17.7 47.3 22.1 0.0 5.0 0.0 1.2 2.2 19.5 2.1 0.0 1.4 0.0 0.0 27.5 0.0 3.3 0.3 6.5 14.6 0.0 0.0 0.3 0.1 3.3 0.4 1.1 0.0 0.7 7.9 0.0 4.3 0.0 2.3 1.7 1.3 0.0 0.0 0.4 3.1 1.6 0.0 2.5 0.5 28.5 0.0 1.4 5.0 0.3 1.5 0.2 0.0 0.5 0.9 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219373527-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 334.9;Late spermatids: 344.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 6200000 Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 20.1 12.3 8.8 15.5 10.4 7.2 20.0 7.2 9.3 16.5 30.4 8.6 13.8 27.9 15.1 13.3 16.9 15.3 16.6 22.9 10.4 6.8 21.2 33.5 15.5 11.7 10.5 7.2 19.4 19.0 9.7 11.0 28.5 9.4 21.0 15.8 15.9 18.7 14.7 36.6 14.6 50.3 12.9 6.8 17.5 15.2 33.7 9.3 11.3 15.0 20.0 17.4 20.7 13.1 11.6 16.1 5.8 15.0 15.7 15.7 10.9 16.2 8.9 5.5 16.2 14.5 12.0 43.5 8.1 16.4 21.1 22.4 24.6 21.4 10.0 17.5 16.8 27.1 15.9 6.5 18.5 7.6 19.4 4.7 16.0 9.1 26.7 38.6 13.3 11.5 19.5 19.7 21.7 18.2 13.6 14.4 13.4 18.0 15.9 10.8 35.3 20.2 14.8 9.0 23.2 5.6 26.3 12.5 13.1 11.8 25.3 6.9 9.3 9.4 31.1 11.4 10.0 9.1 14.7 8.0 20.3 16.8 10.6 11.6 17.9 10.5 7.0 28.9 12.7 8.6 5.8 13.2 5.4 13.6 15.0 15.4 10.2 11.0 15.0 16.1 11.6 12.0 15.7 1.0 15.7 12.2 5.8 12.6 10.9 8.8 10.4 7.2 9.3 10.4 6.8 10.5 7.2 9.4 9.3 11.9 15.6 23.5 61.6 34.3 15.9 28.8 33.1 8.1 11.4 24.4 31.4 76.5 41.4 49.0 334.9 40.7 74.6 0.0 57.6 79.5 42.3 44.7 24.2 41.8 45.2 9.5 46.1 28.8 28.6 344.5 48.6 32.0 30.4 58.7 90.9 28.2 48.4 66.2 38.5 58.6 36.0 25.8 49.1 17.0 16.6 39.1 55.5 30.8 58.7 65.4 DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081100-129090438 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" NA NA Vesicles "Intermediate filaments" "HPA019179: AB_1847827" "unprognostic (1.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-1)" "unprognostic (6.12e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.65e-1)" "unprognostic (4.37e-3)" "unprognostic (7.59e-3)" "unprognostic (2.38e-2)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" 6.4 12.8 10.0 6.8 10.6 7.7 6.8 11.7 19.3 8.3 17.1 17.7 8.6 28.6 6.0 7.4 18.8 6.6 9.2 4.1 10.1 10.7 9.4 21.8 6.7 6.6 13.2 10.6 7.7 10.5 10.4 6.9 11.6 12.5 10.0 14.2 6.1 10.3 5.8 5.2 10.3 27.7 6.3 15.2 8.5 11.8 12.2 11.0 9.4 6.3 8.5 9.1 7.8 8.0 8.8 12.5 9.8 8.3 7.9 21.7 7.2 4.1 16.0 15.7 14.4 5.3 4.5 18.2 10.3 6.0 19.6 11.0 20.6 13.9 8.1 9.1 6.4 15.0 30.3 16.1 8.6 8.3 9.4 9.9 10.6 10.8 15.7 9.4 11.0 13.2 4.9 12.1 12.8 10.2 4.5 8.7 15.1 17.5 8.1 5.5 21.0 12.5 11.4 13.5 30.9 13.0 14.8 12.7 14.5 7.1 6.7 18.0 11.8 13.0 11.8 4.3 9.6 21.7 7.3 7.1 16.9 8.1 15.9 13.9 10.1 19.4 12.3 7.5 2.2 11.1 4.4 6.8 9.8 8.9 8.1 21.7 8.8 10.9 10.8 8.5 6.0 11.1 10.5 1.4 7.9 8.3 12.5 10.1 7.2 10.0 10.6 11.7 19.3 10.1 10.7 13.2 10.6 12.5 11.0 6.0 4.6 3.7 2.9 2.1 3.2 1.6 5.1 0.0 2.3 1.8 5.9 16.9 1.7 5.9 0.5 2.4 26.6 0.0 8.4 11.4 3.3 2.7 5.7 17.0 6.5 3.2 3.5 6.2 3.8 0.4 2.0 2.3 5.0 4.6 9.0 9.1 5.4 13.3 3.9 3.8 3.4 0.0 3.1 4.5 8.7 3.4 13.7 3.8 12.2 3.4 DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "intestine: 161.7;kidney: 52.2;pancreas: 100.5" "Cell type enhanced" "Detected in many" 26 "Leydig cells: 268.4;Peritubular cells: 1144.5;Proximal tubular cells: 391.6" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 5.2;Hep G2: 20.3;HHSteC: 9.2;U-937: 28.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 270000 "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" 0.1 0.4 0.1 0.9 0.1 0.0 0.1 0.1 0.1 1.5 53.6 0.1 0.4 16.1 0.2 3.4 0.3 0.1 0.9 0.1 0.1 0.1 52.2 0.1 0.3 0.9 0.1 0.1 0.2 100.5 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.3 0.4 0.1 0.4 161.7 0.1 0.1 0.9 0.2 9.8 0.1 0.2 0.1 0.1 0.5 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 1.1 0.1 2.8 0.0 0.0 0.0 0.0 5.2 0.1 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 20.3 9.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.7 2.1 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 3.0 2.6 14.9 0.0 0.5 3.3 0.3 0.0 0.0 1.2 22.7 0.0 0.1 48.0 0.3 10.3 0.1 4.2 0.0 171.7 0.3 4.5 0.0 1.1 0.0 0.5 0.0 8.5 1.8 0.0 29.1 268.4 1.7 5.0 1.8 1.9 0.0 43.8 11.5 1144.5 391.6 0.1 6.5 0.3 15.6 2.9 0.3 0.3 0.5 1.2 0.0 DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 105.1" "Cell type enhanced" "Detected in many" 9 "Hofbauer cells: 29.3;Kupffer cells: 40.0;Macrophages: 33.7;Syncytiotrophoblasts: 45.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 43.5;eosinophil: 105.1;neutrophil: 47.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 105.1" "Cell line enhanced" "Detected in some" "HEL: 4.4;HMC-1: 19.9;NB-4: 4.3;U-937: 6.6" "Low region specificity" "Detected in many" HPA035644 Approved NA NA 260000000 "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" 7.8 0.9 1.3 7.1 2.4 13.0 3.5 0.7 2.5 1.5 2.6 2.4 1.1 1.7 4.1 4.1 1.8 2.0 6.8 2.4 1.6 1.3 2.0 2.0 11.4 10.4 2.1 2.0 0.7 0.9 0.1 0.9 19.4 2.7 2.4 2.4 5.1 2.8 0.4 1.6 1.2 10.1 2.3 3.3 26.4 1.6 2.5 1.6 3.5 2.5 3.8 11.1 6.3 1.5 5.0 4.3 105.1 15.3 5.6 4.9 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 4.4 0.0 0.1 0.0 0.1 19.9 0.0 0.1 0.0 0.0 0.1 0.1 1.4 0.3 0.1 0.0 0.0 0.1 4.3 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.1 0.5 0.3 0.0 6.6 0.0 43.5 10.7 105.1 2.3 13.0 2.7 4.1 4.0 1.9 4.3 5.0 4.9 2.5 47.3 5.6 15.3 0.6 4.0 5.7 1.3 2.4 0.7 2.5 1.6 1.3 2.1 2.0 2.7 1.6 0.0 12.2 15.6 0.0 1.8 0.0 1.1 0.0 2.7 2.3 0.0 0.0 7.7 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.6 1.6 0.0 2.3 0.0 29.3 0.0 0.0 17.2 40.0 0.9 0.0 33.7 3.3 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 6.5 6.1 1.1 45.2 13.8 0.0 0.1 DPEP3 ENSG00000141096 "Dipeptidase 3" Q9H4B8 16 67975663-67980829 "Enzymes, Predicted intracellular proteins" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 56.7" "Group enriched" "Detected in some" 7 "Spermatocytes: 154.2;Spermatogonia: 290.0" "Group enriched" "Detected in many" 10 "melanoma: 3.7;ovarian cancer: 16.9;testis cancer: 5.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 9.2;NK-cell: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 9.2;NK-cells: 2.3" "Cell line enriched" "Detected in single" 11 "U-266/70: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031870, HPA058607" Enhanced "Intracellular and membrane" NA NA 16000000 "HPA031870: AB_2674079, HPA058607: AB_2683775" "unprognostic (9.93e-2)" "unprognostic (2.81e-3)" "unprognostic (1.86e-1)" "unprognostic (9.52e-2)" "unprognostic (3.61e-2)" "unprognostic (1.37e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.49e-3)" "unprognostic (9.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-3)" "unprognostic (1.13e-1)" "unprognostic (3.98e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.1 0.4 0.4 1.0 0.6 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.4 1.4 0.2 56.7 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.8 0.1 9.2 0.5 2.3 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.8 0.8 0.3 9.2 2.3 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.3 0.3 0.1 0.1 0.0 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 30.4 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 25.8 0.0 154.2 290.0 0.0 0.2 0.0 0.0 0.0 DPH7 "C9orf112, FLJ90634, RRT2, WDR85" ENSG00000148399 "Diphthamide biosynthesis 7" Q9BTV6 9 137554904-137578935 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Rod photoreceptor cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022911 Uncertain Approved "Nuclear bodies" Yes No "Nuclear bodies" "HPA022911: AB_1858823" "unprognostic (1.43e-1)" "unprognostic (4.81e-2)" "unprognostic (3.41e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.60e-3)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" "unprognostic (9.48e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.30e-3)" "unprognostic (3.06e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.23e-4)" 8.2 12.7 12.1 14.0 16.4 8.2 10.7 15.9 17.8 13.3 12.7 21.5 14.3 5.9 14.2 17.8 9.4 18.2 10.3 12.6 14.0 7.6 11.1 11.0 10.4 13.0 19.1 11.5 17.3 20.8 14.1 14.9 10.5 12.8 15.6 11.9 10.8 16.1 15.4 9.6 13.5 12.2 14.6 9.0 16.0 11.8 10.1 18.6 11.2 13.8 5.8 13.9 10.9 11.7 10.8 14.2 15.6 9.2 9.3 13.5 8.8 7.1 7.5 12.2 10.9 8.8 6.7 14.1 7.1 6.9 12.0 10.2 14.9 7.1 14.0 12.8 7.4 8.9 17.1 14.1 12.1 9.6 11.2 16.5 5.9 10.1 5.4 10.0 13.2 12.7 6.9 10.8 8.0 15.2 9.8 15.9 11.1 11.8 7.5 8.3 20.2 10.0 14.4 14.0 25.8 15.9 17.9 6.4 11.4 9.9 6.7 13.9 12.6 10.9 9.3 7.9 7.7 13.4 13.1 7.5 9.5 7.7 10.9 13.6 6.2 11.9 15.6 4.9 9.1 8.9 15.6 8.9 9.7 10.9 9.2 11.6 10.8 13.5 12.7 10.4 9.5 11.5 11.7 2.3 9.3 6.4 14.2 9.3 8.8 12.1 16.4 15.9 17.8 14.0 7.6 19.1 11.5 12.8 18.6 6.0 14.0 13.7 10.0 14.8 19.0 12.6 5.1 9.4 7.9 1.8 47.1 18.3 3.3 8.7 1.3 11.7 5.1 0.0 8.1 11.4 11.8 10.7 10.4 5.8 10.5 15.9 6.4 8.6 5.7 4.5 15.3 6.9 8.5 10.8 10.6 17.1 10.1 8.0 14.9 4.2 57.2 19.4 13.0 20.5 25.6 16.6 10.2 16.2 13.9 9.1 DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol NA NA 2600000 Cytosol "HPA035780: AB_2674778, HPA035781: AB_10669529" "unprognostic (5.74e-2)" "unprognostic (1.16e-3)" "unprognostic (2.62e-3)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-3)" "unprognostic (1.67e-3)" "unprognostic (1.25e-3)" "unprognostic (1.73e-2)" "unprognostic (9.87e-2)" "unprognostic (1.02e-2)" "unprognostic (3.87e-1)" "unprognostic (5.85e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.81e-2)" "unprognostic (3.43e-1)" "unprognostic (5.66e-2)" 10.4 13.0 5.2 16.8 12.1 10.9 16.9 13.7 11.5 7.3 18.5 9.1 10.3 15.3 10.5 6.8 15.6 7.1 15.7 8.4 9.3 5.9 18.4 31.1 9.8 20.0 9.5 10.6 5.1 11.6 11.2 6.9 10.9 7.4 10.3 16.9 5.7 17.6 8.5 15.8 9.4 15.5 10.0 10.6 12.5 11.8 15.5 6.7 16.1 10.5 10.8 14.0 11.4 8.6 7.5 19.7 12.2 24.4 18.2 17.9 9.9 28.7 25.1 11.6 12.9 9.7 10.5 18.1 16.3 22.0 22.1 14.8 31.5 24.2 16.8 55.7 18.4 18.9 26.0 18.5 20.0 14.3 31.8 8.4 21.8 11.7 18.5 15.0 26.4 36.4 14.8 19.6 16.6 8.2 9.6 16.9 17.7 15.2 10.0 20.1 32.7 30.7 26.9 19.7 28.3 15.3 21.7 11.7 27.5 19.0 24.8 22.0 18.9 13.9 16.3 21.8 11.4 25.2 15.4 17.5 13.3 14.4 14.5 15.9 8.4 15.2 19.1 17.6 12.6 16.2 9.6 11.3 12.2 13.7 24.4 8.4 7.5 10.3 11.4 19.7 7.2 6.3 9.2 2.0 18.2 16.0 13.7 17.9 9.9 5.2 12.1 13.7 11.5 9.3 5.9 9.5 10.6 7.4 6.7 14.9 10.4 20.5 13.8 5.4 10.0 2.8 15.3 9.4 4.5 22.7 9.8 41.2 11.6 43.1 21.0 5.5 31.6 0.0 53.9 28.6 7.1 11.6 1.1 12.4 33.3 6.4 17.9 4.3 7.9 5.3 2.0 12.8 15.1 46.9 17.1 16.1 36.9 21.5 4.9 22.4 61.1 12.9 4.6 7.5 22.2 5.3 30.1 14.9 23.0 17.3 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992241-162074542 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 133.1;parathyroid gland: 75.5" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 134.1;Proximal tubular cells: 80.1;Syncytiotrophoblasts: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "MAIT T-cell: 26.7" "Lineage enriched" "Detected in many" 10 "T-cells: 26.7" "Cell line enhanced" "Detected in many" "ASC diff: 42.8;ASC TERT1: 43.4;BJ hTERT+: 39.8;RPTEC TERT1: 58.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted in other tissues" NA NA 170000000 "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" 9.5 2.9 0.3 3.2 0.5 0.0 5.0 0.3 1.4 2.2 50.0 0.2 36.9 19.1 2.2 3.5 1.2 1.2 5.2 2.1 0.4 0.3 29.1 12.2 5.4 2.1 0.4 0.2 2.7 1.8 75.5 0.3 24.0 0.2 21.1 2.8 0.6 46.9 38.8 2.4 4.4 133.1 0.9 0.8 5.0 1.2 0.6 0.1 6.2 1.0 1.4 1.1 1.0 2.6 0.1 2.1 0.3 0.0 2.6 26.7 2.5 0.0 0.0 0.1 0.0 42.8 43.4 0.1 7.9 39.8 2.2 7.7 8.0 0.2 0.0 3.0 13.7 7.4 0.2 0.1 0.0 1.3 2.5 0.1 0.0 0.0 11.9 17.4 0.0 0.0 4.9 0.0 13.4 0.1 2.0 1.3 0.1 0.0 0.0 0.7 0.0 0.7 0.1 0.4 0.3 16.4 0.0 0.0 0.1 58.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 7.1 4.6 0.2 0.2 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 3.2 0.0 26.7 0.1 8.3 5.2 0.6 0.0 8.3 3.3 0.3 2.6 0.0 2.1 0.9 2.5 0.3 0.5 0.3 1.4 0.4 0.3 0.4 0.2 0.2 0.1 6.0 17.5 0.0 0.3 3.7 1.7 4.0 12.7 4.0 4.5 14.0 9.8 134.1 1.7 3.1 13.0 3.9 21.3 0.0 0.0 52.7 45.7 38.3 12.8 39.9 12.7 0.0 53.0 12.3 1.6 6.2 0.0 4.6 5.0 1.0 11.0 0.0 0.9 11.4 0.0 80.1 0.0 0.0 1.0 2.1 0.8 3.6 143.8 11.4 12.8 0.3 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110542-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 8 "Late spermatids: 751.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 57.2;THP-1: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 1300000 "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: AB_2683999" "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favorable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 28.1 45.2 23.7 23.4 35.3 31.8 20.8 23.5 27.5 21.5 22.0 24.9 40.7 23.2 17.5 35.8 19.1 27.0 30.2 44.7 24.6 29.2 21.0 29.9 25.6 34.8 29.7 25.9 14.3 55.4 23.3 42.5 21.9 24.2 28.8 6.9 32.8 73.1 41.6 25.3 26.9 17.8 22.8 21.7 29.1 24.4 30.9 26.8 18.9 41.2 17.5 24.7 21.3 16.6 20.0 60.8 12.2 43.1 19.2 36.8 38.2 6.9 11.0 0.9 0.9 13.6 10.9 1.4 10.5 17.2 7.0 4.6 10.4 5.7 13.7 11.5 6.9 0.3 15.0 8.0 2.1 0.3 13.4 0.5 6.3 15.2 0.3 30.5 16.9 35.2 13.4 8.3 3.0 6.3 10.2 9.1 17.0 13.8 10.7 4.6 19.2 8.5 16.2 3.7 25.2 10.8 12.5 0.1 57.2 11.1 7.7 17.6 12.2 12.1 31.9 29.7 0.2 11.4 54.9 11.0 17.9 6.1 11.3 7.2 13.2 7.5 3.7 21.4 10.3 8.0 6.8 43.1 12.2 34.4 37.6 35.5 19.7 31.1 29.6 41.7 20.0 28.1 25.1 2.6 19.2 22.6 60.8 36.8 38.2 23.7 35.3 23.5 27.5 24.6 29.2 29.7 25.9 24.2 26.8 50.6 79.4 78.5 85.1 59.5 68.6 52.7 58.6 42.8 46.6 50.6 33.4 44.8 31.5 93.8 230.4 57.3 44.4 23.3 59.4 85.7 82.6 106.0 74.8 62.7 275.2 114.4 84.6 55.3 148.6 751.7 143.8 125.9 158.6 165.1 27.0 123.1 65.3 48.9 159.1 69.0 73.5 51.8 56.5 57.7 46.0 56.8 43.0 127.1 37.4 74.0 DPP8 "DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141" ENSG00000074603 "Dipeptidyl peptidase 8" Q6V1X1 15 65442463-65517704 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008706 Approved Supported Cytosol NA NA Cytosol "HPA008706: AB_1078665" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-2)" "unprognostic (2.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (4.09e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (7.58e-2)" "unprognostic (8.56e-2)" "unprognostic (2.59e-1)" 15.6 16.1 16.4 14.9 18.8 16.2 13.9 22.9 24.9 15.5 14.5 15.0 12.7 18.0 15.9 13.9 13.1 11.1 12.4 18.8 15.1 14.6 16.0 9.9 13.3 16.0 15.4 11.8 16.2 11.7 22.2 14.5 15.9 21.7 13.5 15.8 13.9 15.6 20.8 30.5 14.2 16.5 16.2 17.5 17.2 13.2 29.9 15.8 22.5 17.4 12.5 16.0 16.2 13.2 10.7 8.1 20.0 10.8 6.1 10.3 5.3 9.6 15.6 10.3 10.3 11.6 16.6 8.8 15.5 18.4 13.9 13.4 6.7 8.3 17.0 12.2 19.4 9.5 17.9 19.8 11.2 17.1 14.3 12.3 16.3 12.0 6.4 12.1 21.0 16.1 12.4 10.7 11.3 10.7 11.7 15.2 13.2 11.1 15.8 17.1 7.8 11.2 7.7 7.0 9.8 8.0 14.9 19.0 16.5 11.4 21.0 7.3 12.9 10.1 10.2 15.6 10.6 9.4 12.6 19.2 18.7 13.0 8.8 16.5 20.5 26.8 17.2 14.1 21.2 13.4 20.0 9.1 11.1 9.9 9.2 10.3 9.2 8.6 9.5 8.1 10.7 8.6 9.2 18.3 6.1 10.8 7.5 8.9 5.3 16.4 18.8 22.9 24.4 15.1 14.6 15.4 11.8 21.7 15.8 32.8 24.7 23.1 12.5 11.8 24.3 36.8 25.5 22.7 27.3 14.0 35.3 16.6 19.9 19.2 44.1 27.4 20.3 0.0 26.0 12.3 17.3 17.3 25.6 14.7 18.7 27.0 24.9 43.0 34.3 48.6 27.0 25.3 21.9 30.7 28.3 29.5 29.2 21.0 27.6 24.1 27.0 19.4 17.5 62.7 22.3 17.7 14.8 26.2 24.3 20.9 DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4675224-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol NA NA Cytosol "HPA036059: AB_10671240" "prognostic favorable (4.96e-4)" "unprognostic (4.16e-2)" "unprognostic (2.03e-1)" "prognostic favorable (6.21e-5)" "unprognostic (5.67e-2)" "unprognostic (8.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (8.85e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.38e-8)" "prognostic favorable (7.72e-5)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (1.80e-1)" 18.1 11.9 11.7 24.3 14.0 25.8 13.7 13.0 12.5 12.6 16.3 14.2 15.8 18.3 15.3 10.5 17.4 11.6 13.5 19.7 11.0 7.2 13.5 38.6 19.3 20.7 14.7 7.1 13.5 15.5 9.5 9.8 15.2 11.7 14.0 13.1 14.2 13.1 12.9 46.4 21.5 18.9 14.2 9.3 21.0 14.7 7.1 13.9 24.3 14.6 16.3 17.0 16.0 21.7 10.3 9.0 10.0 10.5 13.4 13.8 8.0 23.8 19.0 5.6 8.8 8.6 12.1 10.2 14.0 18.7 23.6 15.4 17.1 18.5 11.3 10.6 18.1 15.9 16.3 11.4 64.4 14.5 14.5 11.1 8.3 10.4 14.6 13.2 14.4 18.0 9.2 15.0 36.9 21.9 20.2 21.3 7.9 11.3 25.3 20.4 6.5 16.7 9.3 11.5 9.4 28.3 10.5 12.0 13.2 12.3 16.4 8.0 7.2 12.0 21.9 9.2 6.1 6.0 12.0 17.1 21.2 9.2 32.8 27.9 17.6 18.3 11.3 20.7 16.7 17.7 10.0 8.8 9.4 13.8 10.5 10.5 10.3 6.4 11.2 9.0 6.8 6.3 9.9 4.7 13.4 7.8 4.3 11.3 8.0 11.7 14.0 13.0 12.5 11.0 7.2 14.7 7.1 11.7 13.9 26.8 29.1 13.7 11.9 7.0 17.1 12.0 10.2 10.7 11.4 3.5 35.3 10.0 3.3 10.7 1.5 13.5 25.1 0.0 10.9 15.2 7.6 11.0 16.2 35.9 17.2 22.3 12.0 16.5 14.6 2.5 9.2 20.7 5.0 59.5 15.3 8.4 19.7 21.0 8.9 4.5 30.0 19.4 8.1 7.6 6.9 4.8 13.0 18.7 13.7 11.9 DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467053 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 42.2;liver: 103.6" "Group enriched" "Detected in some" 15 "Hepatocytes: 429.9;Proximal tubular cells: 408.7" "Group enriched" "Detected in some" 21 "liver cancer: 57.6;renal cancer: 11.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.2" "Lineage enriched" "Detected in single" 13 "monocytes: 1.2" "Cell line enhanced" "Detected in some" "HDLM-2: 2.7;HSkMC: 2.4;U-266/84: 2.0;U-698: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA024785 Enhanced NA NA 89000 "HPA024785: AB_1847856" "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" 2.5 0.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.2 2.1 0.1 0.0 0.0 0.0 1.6 0.1 0.2 1.3 0.0 0.0 0.1 42.2 103.6 0.2 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.9 0.0 0.2 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.7 0.0 0.0 0.0 1.2 0.0 0.0 2.7 0.0 0.1 0.0 0.2 0.0 1.3 1.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.4 0.0 0.7 0.0 0.1 0.6 1.3 1.4 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 1.5 0.0 0.7 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.4 28.1 0.0 0.0 19.2 0.0 0.0 23.2 0.0 9.9 0.0 0.0 23.3 0.0 0.0 0.6 2.5 0.0 429.9 1.3 0.0 0.0 6.2 6.2 9.7 0.9 0.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 408.7 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526336 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 41.0" "Cell type enhanced" "Detected in some" 15 "Enterocytes: 21.9;Mucus-secreting cells: 12.7;Paneth cells: 11.8;Undifferentiated cells: 10.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HBEC3-KT: 5.9;Hep G2: 16.6;hTCEpi: 6.1;OE19: 14.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039158 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA039158: AB_10960125" "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.1 0.0 0.1 2.1 0.2 0.0 0.1 0.1 0.1 0.8 13.3 0.2 0.1 14.7 0.1 0.1 3.7 0.2 3.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 1.0 0.1 0.2 5.1 0.1 0.6 0.1 0.1 1.5 41.0 0.3 0.1 0.2 2.9 0.1 0.1 0.2 0.1 0.7 1.5 1.1 1.4 0.7 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 0.1 5.9 0.0 0.0 0.3 0.4 0.1 16.6 0.0 0.2 0.3 0.0 6.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.3 14.1 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.1 0.0 2.3 0.0 1.1 0.6 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.0 5.3 1.2 0.0 2.0 1.2 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.5 0.1 11.8 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.9 0.0 10.6 0.2 DROSHA "Etohi2, HSA242976, RN3, RNASE3L, RNASEN" ENSG00000113360 "Drosha ribonuclease III" Q9NRR4 5 31400497-31532196 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, RNA-mediated gene silencing" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031150 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA031150: AB_2673761" "unprognostic (8.37e-3)" "unprognostic (1.81e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (6.79e-4)" "unprognostic (5.40e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (3.11e-1)" "unprognostic (4.08e-2)" "unprognostic (9.08e-2)" "unprognostic (1.86e-1)" "unprognostic (5.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (6.94e-2)" "unprognostic (2.32e-2)" 15.7 16.8 18.4 17.7 32.1 12.2 16.1 33.7 33.7 17.4 16.3 19.1 12.2 15.9 22.3 25.8 16.0 18.2 14.1 15.2 16.6 15.1 15.3 11.7 13.9 17.8 13.6 16.4 26.7 17.8 23.9 38.9 17.0 18.9 17.2 19.2 23.7 17.5 19.2 23.6 16.0 17.5 16.9 19.4 16.8 16.0 12.8 16.4 25.6 21.9 13.4 19.8 18.2 16.2 4.7 6.4 3.3 4.8 4.8 6.4 3.1 12.4 15.7 17.4 23.6 9.3 11.4 25.1 16.5 8.1 15.4 11.5 16.5 16.2 14.0 19.0 12.1 17.9 10.9 21.4 12.5 17.2 13.1 15.1 17.2 51.6 11.9 8.4 19.2 51.4 8.9 8.8 17.2 8.3 11.8 13.1 15.0 21.8 6.6 13.4 12.4 18.5 14.4 16.4 10.1 12.6 16.8 33.3 10.1 8.7 14.2 9.1 12.0 41.9 17.2 10.1 16.2 15.8 11.1 11.4 14.9 17.3 13.3 15.6 12.1 19.8 15.4 10.3 21.7 14.2 1.8 2.4 3.3 5.2 2.6 5.5 4.2 5.4 6.0 5.2 4.7 6.4 4.4 0.8 4.8 4.8 6.4 5.1 3.1 18.4 32.1 33.7 33.7 16.6 15.1 13.6 16.4 18.9 16.4 11.9 14.7 3.0 4.6 3.2 18.2 21.0 7.6 20.1 15.9 5.2 0.0 6.6 3.3 7.2 2.5 6.2 7.3 0.0 7.0 6.4 7.4 5.0 9.2 5.1 6.7 6.4 10.9 9.2 7.8 4.3 10.0 3.2 1.7 9.0 10.1 10.5 7.8 8.6 12.4 4.2 16.8 6.5 4.7 5.8 8.4 3.0 4.1 5.7 10.0 5.1 DTD1 "bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68" ENSG00000125821 "D-tyrosyl-tRNA deacylase 1" Q8TEA8 20 18587893-18766644 "Enzymes, Predicted intracellular proteins" "DNA replication" "DNA-binding, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 137.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA040981 Uncertain Uncertain Nucleoli,Cytosol NA NA 180000 "Nucleoli, Cytosol" "HPA040981: AB_10673268" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.82e-1)" "unprognostic (5.94e-2)" "unprognostic (1.83e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-3)" "unprognostic (9.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.81e-1)" "unprognostic (6.84e-2)" "unprognostic (1.32e-1)" "unprognostic (9.09e-3)" "unprognostic (2.42e-1)" "unprognostic (8.44e-2)" "unprognostic (2.59e-2)" "unprognostic (8.53e-2)" 14.9 17.7 25.2 13.6 26.5 13.6 19.7 22.4 35.4 13.5 13.7 22.2 10.5 10.6 14.4 17.2 18.8 14.5 11.1 16.7 24.7 29.5 20.1 9.4 13.7 15.5 25.2 30.4 19.1 19.7 20.3 23.7 12.7 27.3 13.6 16.0 17.1 17.6 12.4 22.5 17.6 9.8 15.0 30.9 12.7 16.3 20.6 14.4 4.8 29.5 24.9 17.4 13.4 12.6 20.9 27.5 29.9 20.6 16.4 22.5 12.6 18.7 21.1 20.8 20.4 8.9 16.6 11.6 16.6 15.4 13.2 14.5 13.8 14.7 0.0 11.4 15.4 18.5 10.6 16.6 35.2 13.9 9.1 11.9 20.9 4.8 22.9 28.2 16.2 11.3 13.1 28.3 14.9 55.0 11.3 22.4 3.6 13.0 24.4 19.2 27.5 3.4 29.5 19.3 14.2 46.5 0.0 31.0 15.8 20.1 10.1 28.5 21.5 8.9 24.7 42.8 9.5 14.0 10.1 22.1 17.5 9.5 22.3 22.4 19.6 19.4 10.4 12.0 19.0 14.5 29.9 14.5 10.4 22.2 20.6 22.2 20.9 21.7 22.5 27.5 17.8 16.0 16.7 17.1 16.4 20.5 6.4 16.1 12.6 25.2 26.5 22.4 35.4 24.7 29.5 25.2 30.4 27.3 14.4 32.8 20.0 24.2 32.6 20.9 39.1 17.3 30.6 25.4 17.0 40.1 2.0 25.2 36.5 64.2 24.1 30.8 7.3 0.0 76.4 30.7 25.8 26.4 41.5 10.4 41.2 41.3 22.3 24.5 20.4 17.6 16.7 29.6 40.5 48.7 19.7 48.4 68.4 24.6 18.4 51.2 30.2 0.0 17.5 60.6 137.5 31.1 10.4 30.5 24.3 23.6 DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-tyrosyl-tRNA deacylase 2 (putative)" Q96FN9 14 31446036-31457510 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA001117 Approved Approved Vesicles NA NA Vesicles "HPA001117: AB_2666204" "unprognostic (2.56e-3)" "unprognostic (9.38e-2)" "unprognostic (1.27e-3)" "unprognostic (3.24e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" "unprognostic (8.74e-3)" "unprognostic (2.91e-1)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (5.74e-6)" 11.9 11.0 12.4 6.8 16.0 2.9 13.1 9.1 19.6 6.7 6.8 15.2 3.8 5.6 8.0 7.7 9.9 7.5 6.9 6.0 13.2 11.0 8.6 11.6 10.0 8.0 13.6 8.9 8.6 9.9 8.3 9.6 6.2 13.3 8.8 8.2 7.1 10.3 6.1 2.3 8.2 5.3 8.3 10.9 6.7 5.7 14.6 9.9 12.3 9.4 2.8 7.8 7.5 6.5 6.4 6.6 3.5 4.8 6.9 9.1 4.8 8.4 7.2 6.3 8.2 11.6 9.9 4.3 7.8 7.7 6.2 5.5 3.9 8.2 16.2 5.4 8.9 6.7 8.2 9.9 8.8 10.7 8.7 4.4 4.6 5.2 21.7 12.5 9.3 5.7 11.1 10.0 5.5 12.5 5.2 9.1 9.8 9.0 7.8 8.2 10.2 13.4 8.4 8.5 14.7 7.5 9.1 4.6 8.4 11.6 7.4 9.4 6.2 12.8 16.7 9.0 5.6 15.3 4.9 6.5 6.9 6.0 5.5 6.7 9.6 17.9 15.8 3.0 8.6 11.0 3.5 4.8 1.7 4.0 4.1 5.6 4.9 5.9 4.3 6.6 6.4 9.1 6.0 3.0 6.9 2.0 4.0 2.9 4.8 12.4 16.0 9.1 19.6 13.2 11.0 13.6 8.9 13.3 9.9 8.9 7.0 5.2 5.4 4.6 4.3 3.6 7.6 5.3 4.5 3.5 7.9 7.4 3.3 4.8 3.3 3.5 2.7 0.0 5.4 5.3 5.8 4.4 1.1 11.1 4.5 4.8 2.9 1.3 6.4 5.1 6.9 2.9 3.3 2.8 5.9 9.5 4.9 3.5 7.8 6.8 8.3 0.0 6.7 8.1 2.5 4.6 2.3 2.9 7.5 3.8 DUPD1 DUSP27 ENSG00000188716 "Dual specificity phosphatase and pro isomerase domain containing 1" Q68J44 10 75037836-75058514 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 38.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042964 Uncertain NA NA "HPA042964: AB_10795764" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768090-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 326.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 326.0" "Cell line enhanced" "Detected in many" "HHSteC: 43.7;hTCEpi: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol NA NA Nucleoli Cytosol "HPA069577: AB_2686156" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 158.4 78.0 12.4 68.5 14.0 89.7 91.8 17.4 14.9 81.4 37.1 32.4 48.5 9.4 55.4 71.6 82.7 94.8 138.8 49.2 12.5 11.4 29.8 115.4 135.0 43.5 30.6 9.7 69.4 34.4 26.6 40.8 93.7 29.3 67.1 34.2 61.0 38.1 192.8 54.8 116.1 27.6 65.0 29.5 36.1 53.6 45.9 18.7 10.8 90.4 104.1 46.9 69.0 109.7 2.4 11.5 326.0 31.8 4.5 9.8 14.0 2.1 5.5 1.7 2.4 38.1 22.3 2.9 35.4 10.3 23.8 9.6 6.0 2.6 0.7 10.3 24.8 27.4 0.9 1.7 8.7 11.2 19.4 4.7 0.4 12.0 2.5 43.7 0.2 0.8 21.3 76.4 10.8 17.6 12.4 7.4 1.5 1.8 13.9 15.3 2.5 1.1 1.0 1.5 1.6 1.6 41.1 3.2 6.4 16.9 1.1 7.5 3.1 9.6 16.3 1.2 7.6 1.4 0.4 19.5 16.9 8.4 16.4 2.7 2.9 1.6 0.6 15.1 0.3 0.6 33.3 24.6 69.8 3.9 25.0 9.8 2.4 3.5 4.0 11.5 2.1 1.7 1.9 326.0 4.5 31.8 0.6 2.8 14.0 12.4 14.0 17.4 14.9 12.5 11.4 30.6 9.7 29.3 18.7 381.2 398.8 474.0 769.9 1136.9 64.0 181.6 236.9 45.5 126.3 200.7 25.5 239.6 48.0 361.0 67.1 510.4 567.7 46.7 76.6 355.3 824.5 763.6 295.5 297.9 967.3 46.1 687.8 403.9 1172.3 21.1 356.4 1745.4 514.5 55.9 830.1 603.1 188.6 648.8 292.4 25.4 177.1 756.7 886.8 11.8 23.0 1710.3 486.7 546.6 309.1 534.2 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell type enhanced" "Detected in many" 9 "granulocytes: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 15.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 19.2;HaCaT: 42.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favorable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 7.4 4.7 6.0 7.1 11.2 23.2 8.2 5.9 11.1 5.7 10.8 21.1 0.3 2.1 4.9 2.7 7.0 8.5 7.6 3.8 7.2 4.0 2.8 35.4 8.0 9.0 14.0 5.6 2.8 18.3 1.8 2.5 4.5 8.4 3.6 4.9 8.5 9.5 1.7 21.0 8.0 6.2 9.7 10.1 6.4 4.5 3.9 14.1 5.6 5.3 10.6 8.6 8.5 4.1 0.8 5.4 4.6 4.2 15.1 12.7 1.6 6.1 2.6 0.2 0.2 19.2 9.9 0.2 4.1 10.8 6.9 5.3 0.1 1.7 4.8 1.4 10.7 5.0 42.3 0.9 4.0 6.0 12.3 0.5 8.2 1.2 0.7 4.5 3.6 5.6 13.8 2.9 7.4 7.5 3.2 0.2 1.2 0.8 1.7 6.5 0.1 0.7 2.8 0.6 1.3 0.3 0.4 11.7 0.3 2.3 3.7 15.8 1.2 0.5 0.5 17.5 2.5 0.9 2.1 1.5 3.5 0.9 5.3 5.1 2.9 2.0 2.6 5.4 1.6 3.6 4.6 4.2 0.2 3.6 3.7 3.3 0.7 2.5 2.5 5.4 0.8 0.8 1.5 0.3 15.1 1.4 0.2 12.7 1.6 6.0 11.2 5.9 11.1 7.2 4.0 14.0 5.6 8.4 14.1 0.0 1.7 1.9 12.6 45.2 4.5 3.3 10.2 8.1 6.8 3.5 19.6 2.2 0.0 27.3 29.1 6.3 1.0 0.0 7.8 2.7 8.3 10.9 135.7 50.4 22.0 1.6 42.1 1.8 11.0 2.7 23.0 23.9 21.9 13.6 9.9 13.5 21.9 0.0 12.0 0.7 32.3 0.0 5.1 3.8 2.0 36.1 2.9 29.9 2.2 14.4 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavorable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 15.6 12.1 15.0 16.0 17.2 37.8 21.2 27.2 20.3 14.0 14.2 13.9 16.6 11.7 19.5 14.0 12.7 15.6 12.1 11.9 12.6 12.7 14.0 11.4 14.1 18.5 18.6 13.1 18.4 16.7 10.7 18.7 16.4 14.7 13.6 16.0 15.2 13.8 15.1 8.6 12.6 14.4 16.5 12.0 17.4 13.8 8.2 19.4 11.1 15.9 9.4 18.4 14.4 14.1 16.0 17.8 18.7 15.4 23.1 19.4 10.6 18.2 17.3 18.9 12.7 10.1 11.0 17.9 14.6 19.1 22.6 17.5 24.5 16.1 11.1 15.3 17.7 14.2 13.2 14.7 17.9 22.0 14.5 13.0 9.9 15.7 15.9 21.4 21.1 9.9 14.8 19.7 19.6 35.3 12.8 15.7 15.6 17.6 12.2 16.2 17.0 12.3 24.0 30.2 19.4 25.1 18.1 18.5 18.2 12.7 22.5 12.1 25.7 12.4 20.8 24.2 21.7 18.1 24.4 10.9 19.5 18.2 15.2 31.1 20.6 17.0 26.5 12.1 21.4 19.2 18.7 13.9 10.2 16.1 15.4 19.4 15.5 18.1 15.3 17.8 16.0 17.5 19.1 5.5 23.1 9.2 8.2 15.3 10.6 15.0 17.2 27.2 20.3 12.6 12.7 18.6 13.1 14.7 19.4 17.9 10.9 26.6 12.4 12.0 14.1 4.4 7.6 4.0 12.5 7.0 7.9 18.4 18.3 17.8 3.2 19.6 5.3 0.0 21.0 18.7 16.5 15.2 17.4 6.6 17.6 9.5 10.9 16.5 25.1 0.5 8.1 14.3 10.1 19.0 9.7 11.1 16.9 5.8 16.6 14.6 15.6 0.0 20.0 10.6 12.0 11.4 14.8 20.1 11.8 10.7 DUSP13 "BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP" ENSG00000079393 "Dual specificity phosphatase 13" "Q6B8I1, Q9UII6" 10 75094432-75109221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 75.2;testis: 18.6;tongue: 26.0" "Cell type enriched" "Detected in some" 6 "Early spermatids: 345.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39 "neutrophil: 3.9" "Lineage enriched" "Detected in single" 39 "granulocytes: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 5.0;EFO-21: 5.9;Hep G2: 12.2;K-562: 4.7;LHCN-M2: 10.9;RH-30: 9.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "unprognostic (1.79e-1)" "unprognostic (2.39e-2)" "unprognostic (2.39e-1)" "unprognostic (7.07e-2)" "unprognostic (1.66e-3)" "unprognostic (2.47e-3)" "unprognostic (8.63e-2)" "unprognostic (1.97e-1)" "unprognostic (2.63e-2)" "unprognostic (1.27e-1)" "unprognostic (3.92e-1)" "unprognostic (2.22e-7)" "unprognostic (1.93e-2)" "unprognostic (1.54e-1)" "unprognostic (4.81e-1)" "unprognostic (2.09e-2)" 0.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.2 0.0 0.0 5.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.3 0.0 75.2 0.1 0.0 0.0 0.0 0.1 0.0 18.6 0.0 0.0 1.0 26.0 1.9 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 5.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 12.2 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 10.9 0.6 0.0 0.0 0.7 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 1.4 0.0 10.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 345.5 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 54.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 2.6 2.7 1.8 2.5 0.0 0.0 0.1 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489831-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Basal glandular cells: 152.9;Basal keratinocytes: 159.6;Cytotrophoblasts: 141.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 10.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.7;HBF TERT88: 18.3;U-138 MG: 8.7;WM-115: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol NA NA 44000 "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavorable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 4.7 3.7 3.3 2.1 6.6 1.1 3.9 1.8 8.0 3.3 1.0 1.5 0.1 0.7 2.7 1.2 7.2 11.7 5.1 2.6 2.3 2.1 6.5 2.4 1.0 1.9 2.5 3.0 2.9 1.7 3.3 11.6 2.6 1.4 1.4 1.6 2.8 1.1 1.7 8.4 0.9 3.5 2.7 1.7 1.0 3.5 0.8 2.3 8.3 6.1 4.3 1.9 1.0 0.5 0.0 3.2 0.0 0.4 0.4 0.5 1.7 0.1 0.4 0.8 0.0 0.5 1.5 8.2 6.2 10.9 12.7 0.9 1.9 0.1 0.7 5.9 0.1 1.4 0.1 4.8 18.3 0.1 0.6 0.0 1.1 2.0 0.8 0.4 1.3 4.8 2.9 3.8 2.0 0.6 0.2 0.2 0.4 0.0 8.0 0.3 0.8 0.2 0.2 0.0 0.0 0.7 0.5 0.2 2.7 0.7 1.3 0.1 0.4 0.7 1.2 3.2 0.6 1.0 0.8 8.7 2.0 0.1 4.1 0.0 0.2 0.1 0.0 0.0 10.5 0.0 0.0 0.9 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.2 0.3 0.2 3.2 0.4 0.0 0.0 0.0 0.5 6.0 4.8 5.9 152.9 159.6 6.2 14.2 5.1 52.2 26.1 7.0 7.9 141.3 24.9 33.6 35.0 22.7 0.0 0.0 13.2 71.8 47.7 52.8 87.4 10.2 17.0 14.3 2.4 14.7 2.8 40.7 12.7 10.4 59.1 43.3 1.0 9.0 46.1 1.1 5.6 11.8 18.7 0.0 52.6 28.9 29.2 80.9 56.8 6.4 0.8 72.6 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.1" "Group enriched" "Detected in many" 5 "Distal tubular cells: 232.1;Early spermatids: 237.5;Late spermatids: 743.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive B-cell: 1.6" "Lineage enriched" "Detected in single" 14 "B-cells: 1.6" "Cell line enhanced" "Detected in some" "CACO-2: 5.4;REH: 17.7;SH-SY5Y: 5.1;SK-MEL-30: 4.4;U-2 OS: 4.3" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA076649: AB_2686811" "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favorable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.1 2.1 2.8 0.6 4.0 0.5 1.3 1.2 3.7 1.6 0.8 4.2 6.9 0.9 1.4 10.4 0.6 0.7 1.1 2.7 2.8 3.1 15.4 0.6 0.8 1.0 4.9 2.3 2.1 1.8 10.6 2.7 1.1 5.9 1.9 0.5 5.3 2.1 9.3 2.4 0.7 1.0 2.3 5.2 1.0 1.1 75.1 1.4 0.0 3.5 0.1 0.6 0.7 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.9 0.0 5.4 0.1 1.1 2.2 0.3 3.0 0.0 0.4 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.0 3.8 0.7 0.0 0.0 17.7 2.1 0.1 0.0 0.0 2.5 5.1 2.9 0.0 4.4 0.2 1.3 1.1 0.0 0.0 4.3 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.0 1.2 3.7 2.8 3.1 4.9 2.3 5.9 1.4 0.0 0.0 0.0 1.0 0.6 0.5 2.0 2.5 0.0 0.0 17.4 3.9 0.0 232.1 1.7 237.5 0.7 0.0 0.0 0.9 0.1 2.4 0.7 0.0 0.0 0.5 6.4 1.7 3.1 0.0 743.6 8.1 0.8 6.8 1.0 0.0 2.7 0.9 0.0 10.3 33.5 0.2 0.0 1.0 85.0 5.2 0.1 0.1 0.0 0.0 0.1 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12474210-12562383 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 2: 56.3;Intestinal endocrine cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 6.9" "Lineage enriched" "Detected in many" 5 "T-cells: 6.9" "Cell line enhanced" "Detected in many" "NTERA-2: 23.7;RT4: 21.6;SuSa: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favorable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 6.4 32.8 6.3 14.8 7.5 3.4 12.5 16.4 7.1 8.8 13.1 6.7 9.5 13.6 11.0 9.1 9.5 6.8 12.3 5.8 6.7 5.4 6.6 34.2 17.0 13.2 8.0 3.6 8.5 13.9 11.6 31.4 21.3 7.7 13.9 11.7 9.2 17.4 9.5 8.3 7.9 20.1 5.7 9.1 12.2 9.9 8.6 9.2 40.7 10.8 6.8 16.7 10.9 13.4 0.1 0.2 1.4 0.1 0.1 6.9 0.5 2.7 4.0 5.1 2.7 1.8 2.3 8.5 1.6 3.7 4.1 5.9 11.9 5.2 0.2 0.9 1.8 7.2 1.8 9.0 1.5 5.8 8.7 4.5 0.4 4.3 13.3 3.8 0.8 1.8 1.8 4.5 3.3 10.7 4.6 3.1 4.6 2.3 7.3 0.3 5.9 1.0 0.6 23.7 7.1 1.3 1.2 1.7 4.9 2.5 21.6 7.8 7.4 6.5 8.7 4.3 19.7 3.3 1.5 2.8 1.8 5.4 1.1 1.9 5.2 6.0 0.9 2.5 1.8 2.5 0.0 0.0 0.0 1.1 0.1 4.6 0.1 3.2 1.5 0.2 0.1 1.1 0.7 1.4 0.1 0.0 0.0 6.9 0.5 6.3 7.5 16.4 7.1 6.7 5.4 8.0 3.6 7.7 9.2 26.8 56.3 2.9 13.7 2.5 4.2 11.2 17.8 16.0 14.8 3.5 2.0 8.1 0.0 11.0 1.1 6.3 28.9 0.0 21.0 2.7 4.1 30.4 23.1 28.4 4.4 6.4 47.6 6.7 8.3 2.0 5.5 2.6 5.0 4.6 7.1 37.1 19.9 17.6 6.3 4.1 4.8 0.0 3.1 1.6 5.8 1.6 25.2 13.4 16.1 12.8 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667890 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "Early spermatids: 103.5;Late spermatids: 252.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No Nucleoplasm "CAB034070: AB_2094867, HPA051349: AB_2681450" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 5.2 3.9 10.1 7.1 9.7 4.9 5.3 4.1 8.3 5.6 10.1 11.4 4.6 7.8 6.1 8.4 7.5 18.5 8.0 3.8 8.7 7.8 5.5 2.3 9.9 7.2 8.4 3.9 4.4 6.6 5.2 19.5 3.6 9.5 4.6 11.5 4.7 6.1 4.3 2.0 7.9 11.0 6.4 9.0 6.9 8.3 30.8 10.2 8.0 5.8 3.4 7.6 6.0 6.1 6.4 11.2 21.7 13.9 4.3 8.1 4.7 5.3 5.8 2.6 6.5 6.6 13.1 2.5 5.1 5.9 5.2 5.6 3.1 5.7 3.5 3.6 6.4 6.6 4.0 1.6 4.1 5.8 10.0 6.4 1.8 2.0 2.0 2.8 7.5 5.9 3.7 5.8 8.6 3.1 5.8 15.9 4.3 1.8 3.2 5.6 4.6 4.1 1.8 1.0 6.6 3.5 3.0 1.7 1.3 6.3 3.7 6.7 3.8 5.3 2.1 3.7 3.6 4.7 2.1 11.4 10.7 5.8 2.7 2.9 2.3 2.7 1.8 12.1 1.3 5.4 18.3 10.4 19.4 5.9 12.5 4.6 6.4 6.8 5.4 11.2 6.2 4.6 5.5 21.7 4.3 13.9 6.4 8.1 4.7 10.1 9.7 4.1 8.3 8.7 7.8 8.4 3.9 9.5 10.2 17.9 4.8 6.0 10.2 19.1 2.6 1.9 7.6 64.3 11.4 5.2 43.2 1.0 3.3 7.4 103.5 9.0 14.8 0.0 8.2 3.0 9.3 7.5 6.9 0.9 7.3 1.6 34.1 9.8 12.7 252.1 7.8 16.2 8.5 6.4 18.0 9.2 7.0 14.0 6.3 3.0 16.3 6.5 7.2 68.7 18.8 18.6 0.8 8.6 18.5 6.4 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100005 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Ciliated cells: 20.1;Early spermatids: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Yes No Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 2.8 4.6 9.2 2.0 16.3 1.0 3.0 2.9 9.6 3.4 4.7 2.2 3.8 3.5 6.8 9.2 4.2 8.4 3.5 7.4 17.4 3.4 4.7 3.0 3.4 2.3 3.3 6.8 4.4 4.3 7.7 10.6 2.7 3.7 4.2 3.0 3.0 2.8 5.4 3.8 3.4 3.0 8.6 2.9 4.0 9.1 10.4 4.7 6.2 4.6 1.1 1.9 4.0 2.7 4.1 1.5 2.0 0.8 2.2 3.2 1.3 0.1 2.4 2.9 1.4 3.9 2.2 0.0 1.1 1.8 4.6 1.6 2.3 3.0 1.0 6.0 1.2 3.3 0.3 5.7 0.8 3.5 5.8 3.2 10.6 1.8 1.6 1.7 2.6 6.5 1.7 0.5 2.3 1.1 2.9 2.6 0.0 3.1 1.6 2.7 1.0 5.0 2.5 2.4 1.0 2.0 4.9 4.5 0.3 1.0 1.1 3.6 1.5 4.0 1.7 2.9 0.2 0.8 1.0 2.0 2.5 2.1 1.7 0.9 2.0 2.4 0.1 3.1 0.4 3.7 2.0 0.5 1.9 2.3 0.8 2.3 4.1 2.1 3.1 0.6 2.2 2.7 2.7 1.3 2.2 0.4 1.5 3.2 1.3 9.2 16.3 2.9 9.6 17.4 3.4 3.3 6.8 3.7 4.7 0.0 2.7 1.7 1.2 0.9 1.7 6.5 2.5 20.1 2.3 1.8 2.0 2.0 5.0 0.6 10.4 1.0 1.6 0.0 0.6 1.2 1.3 0.9 1.1 1.0 0.6 1.6 2.4 1.8 0.6 4.6 1.7 0.1 0.0 1.8 2.0 4.5 0.5 2.5 2.5 2.3 1.0 0.0 1.4 4.7 3.1 1.4 0.6 0.0 2.1 1.3 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143166-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 151.1" "Cell type enhanced" "Detected in many" 12 "Melanocytes: 136.7;T-cells: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 46.1" "Group enriched" "Detected in all" 10 "NK-cells: 29.6;T-cells: 46.1" "Cell line enhanced" "Detected in many" "Daudi: 15.3;HeLa: 13.9;JURKAT: 14.2;Karpas-707: 17.5;NB-4: 14.5;RT4: 17.4;SCLC-21H: 15.5;U-698: 21.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Nuclear membrane" Nucleoplasm "HPA071920: AB_2686472" "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 6.4 3.1 2.0 13.1 4.3 51.3 2.9 1.3 4.3 4.8 3.9 1.9 7.9 0.8 4.3 18.3 4.1 3.0 8.8 7.4 3.0 1.4 5.5 3.4 15.9 19.0 1.8 0.8 3.0 1.7 0.4 14.6 0.6 2.0 10.7 1.1 2.8 2.0 151.1 1.8 9.8 4.7 3.7 1.6 16.4 2.1 3.3 0.7 43.4 2.4 2.6 12.2 24.6 14.1 3.9 2.3 1.4 2.2 29.6 46.1 7.5 1.5 0.0 0.1 0.1 0.2 0.3 2.3 1.9 0.0 2.8 2.7 4.4 0.3 15.3 5.6 2.1 0.0 1.1 3.8 0.0 0.5 0.2 0.0 0.3 13.9 0.0 1.0 6.3 1.3 0.5 1.0 0.4 0.0 0.0 0.0 14.2 0.0 17.5 0.1 2.6 12.5 14.5 3.4 0.4 5.4 0.0 0.2 12.1 0.1 17.4 15.5 0.8 0.7 0.2 2.8 0.0 1.0 7.2 0.0 0.0 4.1 0.0 0.9 1.2 1.8 21.0 0.0 6.9 0.1 0.5 0.9 0.2 46.1 2.2 22.6 3.9 11.4 41.4 2.3 2.6 7.8 23.9 1.4 29.6 1.8 0.6 3.4 7.5 2.0 4.3 1.3 4.3 3.0 1.4 1.8 0.8 2.0 0.7 0.0 10.6 47.7 90.1 86.0 22.1 33.5 2.5 0.0 1.2 8.7 21.6 0.8 1.7 0.9 0.7 8.2 3.3 0.0 1.2 1.1 24.2 63.5 105.8 2.8 75.6 0.0 84.2 8.6 27.5 0.7 1.7 90.7 136.7 0.0 12.3 1.3 0.9 2.9 1.8 1.0 2.5 0.0 35.3 0.5 4.3 95.9 1.4 346.4 21.8 28.5 DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844004-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 15.9" "Group enriched" "Detected in some" 54 "Early spermatids: 58.8;Late spermatids: 167.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 1.7;K-562: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (5.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.1 0.6 0.0 0.0 0.0 0.0 0.0 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 71.9;U-266/70: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 24.8 13.1 22.0 24.6 31.3 19.4 28.7 12.1 27.5 18.1 29.0 29.8 18.8 21.2 20.6 25.2 29.8 15.0 20.4 31.0 22.6 17.4 16.0 20.3 24.6 27.4 33.5 16.1 13.9 27.9 10.8 14.8 25.9 25.5 16.1 15.9 16.9 20.9 15.5 32.0 30.6 21.8 23.4 29.2 30.0 21.4 41.3 30.0 9.2 19.9 19.0 27.9 22.8 27.4 21.6 18.0 16.3 17.5 2.9 8.2 9.8 3.6 2.2 4.8 7.2 5.6 6.2 6.4 2.7 2.2 2.4 2.9 2.4 4.1 7.7 6.6 2.8 5.1 2.5 6.0 5.0 1.7 18.4 6.9 5.2 1.8 6.6 2.8 1.8 6.8 4.6 15.2 1.7 3.2 4.0 6.8 6.6 4.8 25.7 2.0 2.1 2.7 6.7 2.9 2.7 5.2 5.4 3.3 71.9 4.5 1.6 8.3 3.2 2.3 0.9 7.9 11.0 4.9 2.4 9.3 2.2 2.9 2.2 1.6 36.6 25.8 10.7 0.8 5.1 4.9 16.3 17.5 6.9 5.0 14.0 3.5 21.6 3.9 5.1 18.0 17.5 3.6 5.1 12.0 2.9 12.6 15.4 8.2 9.8 22.0 31.3 12.1 27.5 22.6 17.4 33.5 16.1 25.5 30.0 14.9 17.6 38.7 19.8 23.6 5.2 35.3 10.2 26.8 25.0 5.2 0.0 9.1 18.3 21.3 11.0 33.7 13.8 0.0 45.0 6.9 17.8 14.6 32.3 22.1 25.5 0.0 9.1 22.7 40.0 14.8 14.4 35.8 43.9 83.8 13.0 9.8 28.3 14.0 8.9 14.6 2.6 25.8 27.2 30.7 73.7 32.4 5.5 15.0 14.5 23.5 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.0" "Cell type enhanced" "Detected in many" 8 "Exocrine glandular cells: 394.0;Proximal tubular cells: 620.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HSkMC: 46.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA028211: AB_2672522, HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 25.0 28.0 7.6 9.3 10.5 11.2 27.3 4.4 9.0 15.5 15.9 5.9 6.6 17.2 12.2 15.0 21.2 10.9 12.6 14.9 7.8 5.2 88.0 80.8 12.1 15.4 8.5 4.6 12.3 21.5 12.5 4.3 7.4 9.6 18.0 9.1 9.5 37.8 10.9 32.8 15.8 16.1 7.7 9.6 8.7 11.0 9.7 7.3 5.7 27.0 17.4 11.4 10.5 19.1 13.6 59.7 49.9 43.2 21.3 24.0 24.0 12.2 13.2 0.1 0.0 12.9 11.1 0.1 5.0 4.1 5.9 4.6 5.4 14.1 0.0 30.0 5.5 1.3 0.5 3.4 4.5 3.2 3.0 1.5 16.9 4.8 0.0 19.3 10.2 13.0 46.8 12.3 3.8 13.9 4.3 22.6 0.0 7.7 6.2 8.3 22.2 1.0 0.4 22.9 22.1 18.9 0.0 0.0 5.8 7.2 2.1 5.8 12.8 9.1 20.0 23.4 2.4 12.9 16.0 16.5 4.9 0.2 0.6 0.0 4.4 10.3 0.1 8.3 8.2 3.7 20.0 43.2 49.9 24.0 33.4 13.3 13.6 18.1 22.5 59.7 9.8 11.0 16.4 43.2 21.3 22.1 13.6 15.7 24.0 7.6 10.5 4.4 9.0 7.8 5.2 8.5 4.6 9.6 7.3 38.7 65.7 25.0 97.5 66.2 8.4 26.4 94.3 38.8 83.0 48.8 5.9 13.5 222.2 148.8 39.6 154.1 106.2 0.0 394.0 20.1 31.9 94.9 53.1 219.9 155.2 1.6 34.0 66.3 86.6 5.5 24.5 94.8 40.5 32.5 101.6 59.7 258.6 101.7 14.9 620.9 7.1 12.9 32.0 3.2 13.0 65.1 4.8 43.7 91.6 102.1 DUSP26 "DUSP24, MGC1136" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591332-33600106 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 147.1" "Cell type enhanced" "Detected in some" 12 "Bipolar cells: 76.1;Cardiomyocytes: 54.3;Cone photoreceptor cells: 39.3;Rod photoreceptor cells: 58.5" "Cancer enhanced" "Detected in some" "glioma: 6.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 16 "B-cells: 1.5" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 1.3 9.3 11.5 1.4 13.1 1.1 1.2 18.2 14.8 1.1 1.7 4.2 0.0 2.4 1.5 3.4 3.0 2.3 1.5 20.1 9.1 15.9 1.6 1.0 1.7 1.1 10.6 8.8 15.1 2.2 1.0 14.0 1.0 7.6 2.6 1.5 4.4 1.5 1.3 147.1 1.0 1.9 2.0 10.0 1.2 2.6 1.6 3.8 0.0 1.1 27.0 1.3 1.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 46.2 11.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 13.1 18.2 14.8 9.1 15.9 10.6 8.8 7.6 3.8 0.0 0.0 0.0 0.2 0.0 76.1 54.3 0.0 0.0 0.0 0.0 39.3 0.0 18.3 0.3 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 23.8 24.6 0.0 0.0 4.4 0.0 0.0 1.7 0.0 0.0 13.3 1.6 0.0 5.6 0.8 58.5 0.0 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240564014 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favorable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.8 2.8 2.7 3.0 3.4 7.9 3.5 6.3 3.7 3.1 2.6 3.3 6.5 2.9 2.6 5.0 3.5 3.1 4.4 16.3 2.8 2.7 3.2 3.4 2.5 6.1 3.5 2.4 2.6 10.2 2.6 5.0 3.2 2.8 4.3 2.8 2.7 3.7 2.4 21.2 4.9 4.2 4.3 2.2 5.9 4.2 8.2 2.3 2.6 4.4 13.4 4.2 2.8 4.5 3.8 3.3 10.7 2.1 2.7 3.3 2.0 1.7 1.6 2.2 2.6 1.4 0.8 2.4 1.9 1.2 1.5 1.1 1.0 4.5 2.7 1.0 1.2 2.3 5.1 1.7 0.7 1.6 3.4 6.4 3.9 3.4 2.5 1.0 2.5 6.7 1.7 1.8 1.0 1.3 2.9 0.7 3.9 2.7 3.3 1.3 1.9 3.1 4.0 1.4 2.6 1.4 3.8 4.8 3.6 1.1 2.9 4.9 2.7 1.8 1.9 2.2 1.4 2.4 4.4 1.7 3.5 2.9 2.2 1.7 13.2 3.8 4.4 2.2 1.9 2.8 10.7 2.1 0.7 2.7 1.4 3.0 2.1 2.8 2.8 1.2 3.8 3.3 3.0 3.6 2.7 1.5 3.3 2.2 2.0 2.7 3.4 6.3 3.6 2.8 2.7 3.5 2.4 2.8 2.3 0.0 5.0 5.1 6.9 3.3 6.3 12.9 12.7 6.7 1.2 12.2 3.9 6.4 13.3 4.1 27.6 3.1 11.8 0.0 5.1 4.0 4.1 8.4 6.9 6.6 10.0 7.9 8.1 2.5 10.3 29.8 2.8 7.0 6.8 8.2 8.1 7.4 3.9 11.8 1.4 11.2 6.6 6.5 5.6 41.1 17.6 4.6 5.8 12.5 10.1 6.8 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766121-43778988 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.9" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 19.5;granulocytes: 5.2;monocytes: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol NA NA 1300000 Nucleoplasm Cytosol "HPA063616: AB_2685061" "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favorable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 17.1 17.8 23.1 10.2 20.8 4.6 22.0 14.3 28.6 12.8 28.4 11.1 16.7 13.4 17.5 18.7 23.6 10.6 19.3 64.0 21.5 18.1 27.1 39.9 17.2 9.0 17.6 19.1 9.1 19.2 27.5 11.4 15.0 17.1 22.6 13.1 14.3 11.1 36.6 106.9 8.9 15.2 31.1 12.7 14.5 19.6 8.0 10.8 1.2 13.9 22.8 6.5 20.7 24.1 1.7 19.5 5.2 17.0 0.9 1.7 5.8 10.5 19.2 7.4 7.9 21.6 11.6 6.3 8.0 19.2 18.8 22.8 18.4 7.1 1.6 12.7 15.0 39.0 9.2 11.4 9.8 19.9 3.6 8.7 5.3 8.8 15.0 26.4 0.6 5.6 10.7 17.8 14.5 12.6 20.6 13.1 5.4 4.8 1.8 21.9 7.6 2.7 2.7 3.4 15.1 14.0 3.4 22.3 4.0 26.1 11.2 4.1 7.5 9.4 6.3 23.6 21.3 28.1 14.9 13.6 21.3 14.5 30.2 13.2 9.8 13.0 0.4 25.3 7.5 7.1 5.2 17.0 3.5 1.0 8.9 1.7 1.7 1.5 1.2 19.5 1.6 1.2 1.1 4.1 0.9 10.8 8.2 0.9 5.8 23.1 20.8 14.3 28.6 21.5 18.1 17.6 19.1 17.1 10.8 23.8 16.8 7.2 42.9 19.9 16.3 242.3 48.4 14.7 9.1 40.1 23.6 14.4 34.9 42.9 73.8 32.1 42.0 0.0 50.5 17.5 18.4 41.2 38.1 99.4 73.0 19.1 34.9 27.6 34.5 128.1 13.6 40.3 10.1 32.5 17.6 14.8 50.2 28.1 24.8 69.4 16.6 32.3 35.5 2.4 2.9 25.2 37.6 6.4 14.6 32.8 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350668 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 46.7;pancreas: 78.6;seminal vesicle: 63.5" "Cell type enhanced" "Detected in many" 7 "Basal glandular cells: 94.6;monocytes: 131.7;Pancreatic endocrine cells: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "T-reg: 9.6" "Lineage enriched" "Detected in single" 18 "T-cells: 9.6" "Cell line enhanced" "Detected in many" "A549: 29.9;OE19: 27.1;SK-MEL-30: 46.1;WM-115: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm NA NA Nucleoplasm "HPA061967: AB_2684648" "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 10.9 3.4 1.2 3.6 1.1 3.4 17.1 4.8 2.7 4.6 1.7 1.0 46.7 0.8 3.2 0.7 1.6 1.3 13.1 1.5 4.6 0.8 0.7 0.4 3.7 1.8 0.8 0.8 1.2 78.6 0.1 3.7 17.7 0.7 4.3 0.9 17.1 8.9 63.5 2.7 3.5 1.3 1.5 1.1 0.6 20.6 1.7 0.2 3.9 1.2 2.0 4.7 7.4 3.0 0.0 0.5 0.0 0.0 0.2 9.6 0.1 11.1 29.9 17.8 0.8 2.2 0.0 1.5 2.3 12.7 7.0 3.1 0.3 5.7 0.0 6.3 1.0 4.9 3.6 0.2 7.7 4.2 0.3 0.6 0.0 1.0 0.2 0.0 0.1 14.6 1.4 5.1 2.1 13.1 15.4 5.7 0.1 0.1 1.3 14.0 12.6 0.0 2.0 3.1 27.1 18.4 0.3 0.5 2.3 16.1 5.9 0.1 9.8 3.2 15.2 46.1 0.3 3.2 0.3 16.0 5.1 0.0 0.0 1.6 3.5 0.4 0.0 15.6 2.6 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 9.6 0.1 1.2 1.1 4.8 2.7 4.6 0.8 0.8 0.8 0.7 0.2 0.0 3.2 1.4 94.6 10.8 34.2 1.9 28.1 29.4 15.9 0.0 11.8 2.7 0.0 64.0 3.5 10.8 0.4 0.0 66.9 37.5 8.4 20.9 5.8 0.0 19.5 41.3 93.8 19.6 5.0 19.7 0.3 25.0 62.4 131.7 7.6 0.9 166.3 0.0 0.0 0.0 2.8 12.9 12.2 0.6 0.4 10.5 14.9 8.5 2.2 92.0 DUSP5 HVH3 ENSG00000138166 "Dual specificity phosphatase 5" Q16690 10 110497838-110511544 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Basal glandular cells: 372.8;Urothelial cells: 958.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.4;non-classical monocyte: 8.8;plasmacytoid DC: 13.3" "Group enriched" "Detected in many" 19 "dendritic cells: 13.3;monocytes: 8.8;T-cells: 3.4" "Cell line enhanced" "Detected in many" "hTERT-HME1: 87.7;Karpas-707: 34.0;U-266/70: 48.5" "Region enhanced" "Detected in many" "cerebellum: 68.0" "Region enriched" "Detected in many" 5 "cerebellum: 41.9" NA NA "unprognostic (1.25e-1)" "unprognostic (3.57e-1)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (8.30e-6)" "unprognostic (1.70e-2)" "unprognostic (4.60e-2)" "unprognostic (2.91e-2)" "unprognostic (1.20e-2)" "unprognostic (4.20e-3)" "unprognostic (3.79e-1)" "unprognostic (3.78e-3)" "unprognostic (2.32e-1)" "unprognostic (9.09e-2)" 13.7 11.0 2.8 12.4 5.1 14.5 11.2 19.8 5.2 15.1 12.5 3.3 7.7 5.4 9.1 8.8 55.5 5.6 24.2 11.3 5.2 3.3 9.1 13.1 12.1 9.3 2.9 2.8 6.5 3.9 5.5 8.0 45.1 5.6 15.6 12.4 21.0 9.4 10.0 1.8 6.5 17.6 10.3 7.1 11.4 10.2 13.1 2.1 4.8 7.8 21.9 47.8 31.6 14.3 0.2 13.3 0.4 8.8 0.0 3.4 0.5 4.4 3.0 0.6 1.5 2.4 10.2 2.2 10.6 24.0 5.7 6.9 1.9 6.0 0.5 2.0 2.5 12.2 1.4 0.6 5.5 9.3 12.7 0.3 2.4 0.5 1.1 9.1 0.6 3.2 3.9 7.6 18.2 87.7 2.5 3.5 0.2 0.4 34.0 17.0 1.2 0.1 1.8 2.0 0.4 4.6 0.0 1.3 7.8 19.5 8.7 0.3 0.8 0.7 1.7 3.5 5.7 0.9 0.7 5.5 1.9 1.3 4.6 5.0 48.5 8.6 1.2 7.5 3.3 1.3 0.4 0.2 0.0 3.4 2.0 1.2 0.2 1.8 1.0 0.9 0.0 0.0 1.1 0.1 0.0 8.8 13.3 0.0 0.5 2.8 5.1 19.8 5.2 5.2 3.3 2.9 2.8 5.6 2.1 3.0 8.5 17.2 372.8 58.6 8.2 28.2 7.6 0.0 18.2 33.2 5.9 30.4 5.0 26.2 1.0 35.0 36.5 0.0 4.2 9.9 26.3 104.8 3.5 4.0 9.3 0.0 46.8 165.1 18.3 1.9 1.4 20.8 150.1 76.7 7.8 2.5 31.7 14.0 0.7 0.3 10.6 0.0 31.1 1.0 9.1 89.1 114.9 25.9 7.6 958.4 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347232-89353271 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 125.0" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 270.1;granulocytes: 438.5;Kupffer cells: 216.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Group enriched" "Detected in many" 11 "granulocytes: 125.0;monocytes: 79.7" "Cell line enhanced" "Detected in many" "AN3-CA: 82.0;NB-4: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favorable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 37.7 7.5 7.2 15.9 11.7 41.3 24.1 3.4 14.7 11.6 12.4 6.2 5.8 6.1 9.8 8.7 12.0 15.4 25.1 16.2 10.5 6.5 17.1 38.4 28.2 13.3 6.9 7.4 7.5 12.2 15.0 13.7 19.7 7.9 17.4 15.3 44.4 64.3 6.3 12.0 8.5 14.6 11.3 7.1 28.4 10.3 4.8 6.4 6.1 21.0 13.3 17.8 15.2 6.9 1.2 9.2 125.0 79.7 1.2 0.9 32.4 1.1 1.1 24.4 82.0 21.1 18.0 0.0 8.8 11.2 1.8 1.3 7.2 1.3 0.0 2.1 3.7 3.4 9.4 0.1 22.0 2.5 0.1 0.1 3.6 0.2 11.4 15.0 15.7 40.2 3.5 7.7 15.5 14.5 18.4 40.7 0.4 0.0 3.8 5.6 0.5 0.5 58.8 14.8 28.0 20.0 40.0 3.0 1.5 25.2 23.7 0.4 17.4 0.2 0.1 46.7 8.7 1.2 8.8 10.9 6.0 0.1 1.1 4.2 0.6 3.2 0.1 24.9 11.1 38.0 125.0 49.5 22.4 0.9 79.7 0.4 0.2 0.2 0.3 9.2 1.2 0.1 0.3 22.5 1.2 74.4 1.2 0.6 32.4 7.2 11.7 3.4 14.7 10.5 6.5 6.9 7.4 7.9 6.4 95.3 270.1 20.5 66.1 80.7 1.2 8.1 53.5 22.7 111.5 171.0 31.4 63.9 14.9 10.9 1.1 97.2 31.9 0.0 11.9 2.9 29.6 20.6 438.5 128.2 43.3 1.6 18.4 173.1 216.2 1.4 1.4 140.4 11.8 1.8 11.0 9.0 12.3 7.4 3.2 23.5 2.0 25.8 8.5 1.2 1.1 21.7 41.2 18.5 12.8 23.4 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056550 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 12 "Basal keratinocytes: 104.2;Suprabasal keratinocytes: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 41.4;hTERT-HME1: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved NA NA "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavorable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 5.5 5.9 7.8 4.3 8.5 1.6 3.7 6.5 19.2 8.6 2.9 15.3 3.4 2.4 5.6 2.4 22.0 4.4 5.3 8.3 7.3 4.8 3.6 2.5 7.0 5.6 9.9 10.0 4.7 4.3 3.9 3.8 8.9 4.9 4.0 2.3 4.6 5.2 5.3 11.4 24.1 3.5 4.2 4.8 10.7 3.7 5.4 9.2 3.2 3.4 15.0 8.6 5.8 14.7 1.0 7.5 1.7 10.7 2.3 8.2 1.7 7.6 1.6 1.9 4.4 6.3 5.5 2.3 7.7 14.8 7.7 5.6 2.1 3.9 2.1 2.1 11.4 3.9 9.0 7.4 28.0 5.3 1.8 3.0 10.0 3.9 3.7 5.1 8.9 6.1 5.7 41.4 9.9 35.3 5.3 7.3 6.2 5.7 6.1 6.1 2.1 6.6 12.7 4.8 2.1 14.0 5.6 1.7 5.6 3.2 3.3 2.4 7.2 3.4 3.2 5.4 1.6 1.1 21.6 9.5 14.9 9.6 15.6 23.5 2.9 2.7 3.4 8.2 15.1 4.7 0.9 3.9 1.7 6.0 10.7 8.2 1.0 7.2 4.3 5.0 0.6 5.3 4.8 1.4 2.3 10.0 7.5 4.6 1.7 7.8 8.5 6.5 19.2 7.3 4.8 9.9 10.0 4.9 9.2 8.9 0.6 1.5 23.5 104.2 4.7 15.3 0.0 1.4 5.7 0.0 0.0 0.4 1.7 3.3 1.1 11.3 0.7 0.0 2.3 3.4 9.0 3.2 0.0 0.4 6.7 0.0 2.4 28.3 10.7 0.0 8.1 8.3 20.3 0.0 2.9 0.9 7.4 0.0 4.6 0.9 1.0 25.8 15.1 3.2 4.3 118.3 1.0 4.5 2.9 24.4 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell type enhanced" "Detected in many" 10 "Bipolar cells: 101.5;Cone photoreceptor cells: 45.2;Horizontal cells: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;MCF7: 6.2;SH-SY5Y: 5.5;U-251 MG: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol NA NA Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favorable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.2 0.4 1.2 0.0 0.0 0.1 0.0 0.3 0.0 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.0 0.1 0.1 0.0 1.8 0.0 6.2 0.0 0.4 0.0 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 3.0 0.6 0.0 5.6 8.8 101.5 5.2 5.1 0.0 0.0 12.2 45.2 0.1 1.7 6.9 0.2 2.2 22.7 0.0 9.6 0.4 4.5 12.8 0.0 0.4 0.4 85.8 40.5 1.3 0.0 0.0 0.6 0.3 5.0 1.8 20.2 16.0 9.8 17.5 0.4 1.1 36.7 6.5 5.1 0.2 0.4 4.3 4.9 1.3 16.8 9.8 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 23.0;placenta: 63.1" "Group enriched" "Detected in some" 14 "Cytotrophoblasts: 876.9;Distal tubular cells: 616.8;Syncytiotrophoblasts: 1451.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Hep G2: 90.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "amygdala: 4.4;basal ganglia: 2.7;cerebral cortex: 3.5;hippocampal formation: 3.7;hypothalamus: 3.6" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.1 3.2 0.2 4.4 0.1 0.3 0.2 2.0 0.2 0.1 0.7 0.0 0.2 0.1 0.3 0.3 0.2 0.1 0.2 2.5 0.6 23.0 0.7 0.2 0.2 1.1 0.6 1.9 0.5 0.1 0.0 63.1 0.9 0.2 0.1 0.0 0.8 1.5 0.1 0.2 0.2 0.1 0.5 0.2 0.2 1.1 0.8 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 8.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.6 0.5 0.0 4.0 0.0 0.3 1.8 10.1 0.2 0.0 0.2 1.8 0.0 0.7 90.8 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.2 0.2 0.4 3.7 0.0 0.0 0.0 0.0 2.3 0.1 0.3 0.6 0.7 0.3 0.2 0.1 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 0.2 2.0 2.5 0.6 1.1 0.6 0.9 0.8 0.0 0.0 0.0 0.6 0.6 0.0 1.8 0.0 0.0 0.0 10.4 0.0 876.9 616.8 0.1 0.0 0.0 0.0 0.0 0.0 57.4 0.2 0.3 0.0 0.8 72.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 0.0 0.0 0.0 0.7 8.3 0.0 1451.1 0.0 0.0 0.9 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm No Yes Nucleoplasm "HPA054422: AB_2682483, HPA060360: AB_2684262" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 26.9 32.9 23.2 51.1 31.8 69.0 31.9 31.7 27.6 26.8 26.3 24.4 27.2 14.5 29.8 31.8 33.7 26.9 28.2 35.5 23.2 26.5 25.4 19.8 25.7 44.7 25.3 23.6 33.4 22.2 23.7 30.7 26.0 22.5 30.3 24.3 28.1 27.5 26.1 25.6 27.3 22.6 25.6 23.9 30.1 25.8 31.9 20.7 120.3 40.5 37.7 43.2 23.5 28.4 34.5 32.3 17.0 24.5 22.2 40.2 24.3 26.1 8.2 20.1 19.0 14.1 15.0 12.0 27.8 17.7 25.7 31.9 9.5 18.1 73.0 15.0 15.2 21.0 36.0 21.1 19.0 25.2 51.4 21.8 59.6 21.7 12.9 7.8 62.4 28.4 9.2 12.9 17.4 9.2 16.7 17.0 43.7 32.2 41.5 18.9 10.6 55.8 73.5 12.7 26.7 15.9 45.5 44.0 76.7 16.9 17.8 29.2 29.7 20.6 16.7 23.8 21.4 23.6 49.8 14.1 26.9 26.0 32.0 36.4 33.5 69.7 71.9 20.3 107.2 29.5 11.3 19.5 17.0 21.7 19.3 28.1 34.5 38.9 34.2 28.2 31.6 40.2 26.5 11.1 22.2 24.5 32.3 34.4 24.3 23.2 31.8 31.7 27.6 23.2 26.5 25.3 23.6 22.5 20.7 50.6 29.3 108.7 177.4 159.5 41.9 99.9 84.1 24.1 61.4 99.5 13.7 138.0 172.5 82.7 26.1 112.3 21.0 140.2 40.7 245.0 140.4 116.4 84.1 71.8 150.1 77.9 92.4 100.1 85.2 25.7 171.2 102.9 146.8 57.7 93.4 81.1 44.6 42.1 166.9 204.1 36.1 155.2 162.6 380.2 218.4 147.3 81.2 113.3 168.7 147.0 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345504 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 114.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 21.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 103.3;TIME: 91.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 2100000 "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 44.0 49.9 10.3 18.7 14.5 17.3 33.7 3.6 15.6 29.5 27.5 19.2 11.2 12.4 24.0 10.5 15.6 19.1 23.0 30.9 12.4 8.0 14.9 41.8 30.1 14.4 13.9 13.4 34.2 42.1 114.4 21.6 27.0 14.6 27.9 14.6 26.5 14.7 11.4 15.2 14.8 23.2 24.1 13.2 23.5 18.9 19.1 14.7 9.5 23.2 10.7 19.1 34.2 37.0 4.6 2.0 21.5 7.5 1.0 6.1 4.2 13.8 9.3 12.0 6.0 17.4 18.6 6.9 20.7 36.1 11.3 10.4 6.7 42.8 5.0 52.1 20.8 24.4 5.9 4.9 9.9 9.9 12.6 4.1 7.2 14.4 5.4 23.2 1.0 1.8 9.7 11.6 17.4 8.7 30.9 103.3 4.1 1.4 2.7 9.5 2.9 2.1 1.6 3.6 3.9 7.3 2.5 6.9 7.2 17.6 2.5 4.1 10.0 20.5 12.1 8.9 6.8 8.7 3.0 91.7 25.5 12.4 11.2 11.9 4.1 7.0 5.8 52.9 2.4 30.7 0.1 5.8 2.2 2.2 7.5 3.3 4.6 4.6 3.5 0.5 3.1 3.1 1.9 21.5 1.0 5.2 2.0 6.1 4.2 10.3 14.5 3.6 15.6 12.4 8.0 13.9 13.4 14.6 14.7 17.9 9.8 18.9 17.1 18.0 1.9 16.1 7.6 10.7 28.4 22.7 0.0 3.6 5.0 21.9 1.1 83.9 51.8 23.3 49.4 26.8 34.3 33.0 18.4 32.5 3.1 0.0 24.2 95.8 8.2 1.7 40.3 5.1 6.8 27.9 10.9 57.2 80.7 84.2 51.9 7.4 4.7 38.8 42.9 1.1 4.7 14.1 8.8 10.7 20.9 38.3 EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690231-184754913 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: AB_2672205" "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" 12.5 12.6 10.8 11.3 13.8 6.4 11.1 15.2 11.8 13.2 17.6 7.5 10.8 16.0 11.7 7.7 10.9 10.2 10.4 10.4 9.1 8.2 9.6 27.8 13.3 8.9 13.5 8.4 8.8 27.3 18.4 26.4 17.9 10.6 12.3 21.3 7.6 18.3 14.3 20.8 7.1 14.4 10.6 13.3 9.5 31.3 6.2 11.5 15.8 11.5 6.3 10.6 11.6 16.1 2.7 5.9 7.4 6.8 4.0 6.3 3.4 6.6 5.0 7.0 6.1 25.4 26.2 11.3 13.5 9.4 5.2 5.4 2.6 19.3 4.6 14.8 10.2 5.2 9.1 6.6 7.0 7.6 4.5 5.4 6.1 5.3 3.7 9.8 15.9 9.0 14.9 8.7 12.5 11.2 9.7 13.8 12.5 16.0 21.7 9.8 5.5 12.7 8.3 9.7 15.1 4.7 5.6 5.3 15.8 7.5 4.7 7.8 11.1 6.6 11.5 9.3 12.1 10.8 25.0 16.2 7.4 3.4 15.7 11.3 33.3 12.8 6.2 9.9 18.2 16.2 7.4 6.8 4.1 2.9 6.7 5.1 2.7 4.5 3.5 5.9 2.0 6.3 3.3 6.9 4.0 6.3 3.0 3.0 3.4 10.8 13.8 15.2 11.8 9.1 8.2 13.5 8.4 10.6 11.5 17.9 13.4 12.2 6.8 14.8 27.8 13.7 10.2 22.7 23.9 14.0 23.6 10.6 0.0 11.1 14.7 22.4 27.1 0.0 30.7 9.0 21.5 26.1 20.7 38.0 11.5 20.6 29.4 20.9 41.6 5.6 19.0 19.1 18.6 4.6 60.6 8.0 21.3 21.0 17.0 8.1 14.2 19.4 14.1 14.3 8.1 17.9 16.2 13.1 29.1 15.2 EIF3F "eIF3-epsilon, eIF3-p47, eIF3f, EIF3S5" ENSG00000175390 "Eukaryotic translation initiation factor 3 subunit F" O00303 11 7970251-8001862 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis, Ubl conjugation pathway" "Hydrolase, Initiation factor, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049250 Approved NA NA 18000 "HPA049250: AB_2680692" "unprognostic (1.11e-2)" "unprognostic (1.42e-1)" "unprognostic (8.46e-2)" "unprognostic (1.15e-2)" "unprognostic (8.50e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.16e-1)" "unprognostic (1.97e-1)" "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (1.57e-1)" "unprognostic (5.66e-2)" "unprognostic (2.61e-1)" "unprognostic (8.36e-2)" "unprognostic (8.78e-2)" 38.2 28.5 19.8 40.4 22.0 36.6 50.8 16.4 22.7 44.4 41.4 23.2 35.0 25.4 40.6 35.7 45.8 41.1 42.6 38.6 17.0 14.7 29.7 32.2 33.9 82.2 19.9 20.4 74.6 67.4 23.0 23.5 28.9 17.8 45.0 31.2 26.2 49.2 29.7 71.4 56.8 31.7 54.2 20.1 37.1 40.9 42.5 20.0 88.5 50.8 47.7 51.6 48.0 55.5 60.4 48.1 14.7 35.6 34.7 65.7 70.3 30.3 19.5 31.4 23.3 40.3 75.3 29.2 24.3 35.6 26.6 26.6 20.3 42.1 53.5 12.8 29.7 26.1 22.0 21.2 45.9 33.7 15.7 39.7 23.2 23.3 30.1 69.1 29.7 23.4 60.1 44.7 15.0 49.7 49.4 32.9 32.0 18.9 22.8 33.3 20.4 34.6 39.9 28.5 26.8 29.1 44.1 18.0 20.7 26.7 31.4 20.9 43.5 13.7 23.9 25.6 28.0 20.0 22.6 24.9 18.7 28.3 12.4 17.9 21.0 27.5 26.5 19.7 14.7 25.0 14.0 35.2 14.7 31.9 35.6 44.7 60.4 54.6 39.8 48.1 53.7 65.7 48.3 5.4 34.7 32.9 34.6 60.5 70.3 19.8 22.0 16.4 22.7 17.0 14.7 19.9 20.4 17.8 20.0 101.3 120.9 368.1 288.7 310.1 69.7 83.7 221.7 100.4 105.8 75.0 49.1 562.0 248.7 238.1 348.2 252.8 135.7 70.0 385.2 576.6 282.7 202.6 161.6 136.4 301.0 42.9 201.8 203.1 365.6 632.9 227.9 316.4 234.5 473.5 241.1 83.9 327.6 228.0 184.9 219.6 63.1 97.0 272.0 108.2 90.1 384.9 471.2 365.7 352.3 377.1 EIF4A1 "DDX2A, EIF-4A, EIF4A" ENSG00000161960 "Eukaryotic translation initiation factor 4A1" P60842 17 7572706-7579005 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Basal keratinocytes: 1192.5;Suprabasal keratinocytes: 1078.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011689, HPA068286" Uncertain Approved Cytosol NA NA 2300000 Cytosol "CAB011689: AB_732122, HPA068286: AB_2685968" "unprognostic (1.49e-2)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.17e-1)" "unprognostic (2.49e-1)" "unprognostic (2.12e-3)" "unprognostic (7.25e-2)" "unprognostic (2.89e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-2)" "unprognostic (2.65e-2)" "unprognostic (5.19e-3)" "prognostic unfavorable (1.76e-8)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.13e-2)" 56.5 49.0 19.3 41.4 19.8 51.4 80.2 13.6 26.6 40.4 45.6 28.5 26.4 28.7 45.9 30.2 76.4 43.4 39.2 33.5 18.5 17.1 34.2 58.0 46.3 135.7 27.7 12.9 55.2 77.0 19.8 28.8 45.2 21.8 36.2 44.0 33.0 65.8 30.7 36.5 48.4 30.9 46.5 33.4 46.8 42.2 31.6 21.8 91.5 34.7 73.8 67.7 42.5 40.8 35.1 143.6 29.1 115.7 47.1 60.3 170.1 85.9 117.9 79.1 71.6 71.2 83.3 73.8 83.0 94.4 154.0 119.1 119.0 39.0 117.7 64.0 87.0 67.6 77.2 167.7 127.8 166.0 38.1 124.3 66.3 76.7 132.2 109.0 67.7 67.1 110.3 66.1 129.3 132.3 92.1 115.5 66.8 67.6 24.4 110.8 90.4 70.3 58.2 67.8 89.0 81.7 66.4 59.7 56.5 107.6 79.1 41.8 81.2 74.8 50.4 104.0 61.8 55.9 52.1 82.5 81.4 56.8 52.0 166.9 24.0 33.4 77.1 87.5 83.4 89.2 19.6 115.7 29.1 37.0 102.6 60.3 35.1 40.0 39.5 143.6 28.9 39.4 39.6 12.1 47.1 75.7 54.8 49.2 170.1 19.3 19.8 13.6 26.6 18.5 17.1 27.7 12.9 21.8 21.8 107.2 246.6 70.7 485.7 1192.5 106.4 4.8 71.4 168.6 257.0 69.8 110.0 292.0 129.3 287.6 27.4 250.8 114.3 0.0 199.9 314.2 406.1 269.6 140.3 57.2 188.0 100.1 111.9 143.1 130.1 33.1 149.0 241.8 688.4 127.2 116.0 108.1 249.6 126.3 102.6 131.4 109.7 148.8 550.1 57.5 86.6 1078.3 532.6 174.8 147.8 417.5 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789900 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 1000000 Cytosol "CAB011690: AB_732123, HPA068286: AB_2685968" "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 34.6 66.1 61.2 27.7 79.9 1.9 53.5 121.1 111.5 65.1 52.1 26.5 30.1 30.3 73.1 45.5 44.5 73.9 45.1 83.7 58.4 71.9 63.9 43.5 33.7 36.1 48.9 61.7 142.0 59.0 30.9 84.1 47.3 69.6 57.9 40.1 31.8 43.7 62.8 126.7 19.8 35.6 57.1 41.9 32.5 39.0 32.9 39.5 23.9 67.8 36.4 35.4 61.1 51.7 55.1 19.3 39.4 24.8 33.0 63.4 51.3 10.1 5.1 21.4 3.5 82.7 78.0 6.6 18.3 16.5 19.4 25.6 18.9 3.7 22.7 102.5 26.2 35.9 17.1 31.5 7.7 34.3 21.2 16.6 36.6 6.8 25.3 32.4 7.7 25.7 52.2 37.0 5.6 46.7 98.7 34.4 19.2 12.3 38.3 63.1 1.7 12.2 3.8 21.3 41.0 24.6 15.7 15.2 13.8 38.5 12.4 42.2 8.5 29.7 20.5 38.9 56.7 32.0 28.2 25.1 15.4 7.7 14.8 11.2 30.5 43.2 10.4 10.6 8.1 7.2 39.4 16.0 18.5 28.5 18.2 45.3 55.1 41.9 34.8 19.3 46.1 63.4 50.2 11.0 33.0 24.8 17.4 38.6 51.3 61.2 79.9 121.1 111.5 58.4 71.9 48.9 61.7 69.6 39.5 110.2 187.7 337.3 695.6 613.2 269.9 244.1 206.4 220.8 192.2 247.7 60.9 410.2 560.3 199.1 25.8 233.7 293.3 23.3 81.4 227.6 351.3 637.4 309.0 119.2 199.9 368.7 391.5 183.0 192.6 37.8 357.2 230.1 327.3 376.9 296.7 294.3 160.6 364.6 444.5 452.5 161.0 232.8 455.3 100.9 174.0 540.1 514.8 331.3 287.0 611.0 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80135214-80147183 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm NA NA 73000 Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favorable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.68e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 27.3 37.0 19.6 23.6 21.5 71.7 22.0 20.3 19.8 24.2 23.8 16.9 19.2 16.2 24.9 18.0 41.5 29.4 17.1 24.2 17.8 12.3 24.5 20.3 21.6 25.4 16.8 19.7 37.5 16.8 17.1 21.9 38.3 13.1 24.7 20.9 14.7 22.1 31.2 19.8 31.2 18.6 18.5 13.7 25.5 20.4 35.1 19.3 30.7 26.9 26.4 30.6 28.9 25.8 38.7 80.4 33.1 41.9 30.2 38.9 48.3 48.1 43.2 28.6 21.1 22.0 13.4 25.0 25.6 18.2 36.3 29.2 46.0 22.5 44.1 17.2 22.3 26.0 32.1 39.1 27.3 40.4 16.2 41.0 27.6 34.2 49.6 21.7 49.7 29.0 20.5 14.0 30.4 24.7 14.7 29.6 25.8 36.7 28.6 21.4 36.8 44.8 25.3 30.7 44.4 40.0 37.1 57.9 34.8 17.7 41.2 39.8 21.7 35.2 68.9 29.5 28.1 45.0 33.5 20.3 22.5 28.9 33.1 40.3 25.1 21.6 81.4 18.2 31.4 23.0 25.7 41.1 33.1 26.7 41.9 34.5 38.7 34.5 30.8 50.3 31.6 32.0 30.7 24.4 30.2 32.9 80.4 38.9 48.3 19.6 21.5 20.3 19.8 17.8 12.3 16.8 19.7 13.1 19.3 38.7 49.5 57.4 240.8 251.5 20.3 50.7 30.6 36.1 62.6 27.9 15.7 121.7 54.7 70.9 25.8 58.9 51.0 23.3 101.3 178.8 96.2 78.8 91.1 26.0 94.7 6.4 57.8 30.7 62.3 10.0 62.2 81.9 97.8 83.8 45.6 43.1 73.7 52.7 46.7 47.7 27.1 84.1 170.0 87.7 109.4 261.3 219.0 53.3 56.0 264.3 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337353-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA NA 11000 Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 24.5 16.0 25.2 22.4 32.6 11.5 22.6 27.7 26.0 23.7 25.1 10.5 19.9 14.8 19.4 28.7 30.8 14.5 15.0 61.7 26.0 22.3 28.8 32.1 17.9 19.2 26.9 23.0 22.3 24.6 26.8 27.5 26.4 28.5 26.0 20.3 7.1 22.3 29.1 105.8 25.3 19.3 31.5 37.6 27.0 20.7 22.6 33.8 17.8 18.2 29.2 22.8 40.1 31.9 15.9 20.2 11.6 12.1 14.1 14.9 4.5 34.1 17.1 19.5 25.4 23.7 28.1 32.4 30.2 19.0 20.1 20.1 39.3 24.4 39.2 26.2 22.4 23.9 19.6 34.1 29.2 35.6 23.6 20.4 47.1 17.5 51.7 18.8 46.0 29.1 18.9 20.6 27.9 28.6 17.3 29.2 24.1 51.9 19.6 28.9 27.7 29.1 42.7 30.4 22.5 25.2 25.5 29.1 31.9 41.2 28.7 16.6 15.7 16.4 37.8 24.3 38.8 15.3 30.4 32.0 31.3 30.7 16.3 26.8 14.6 20.6 32.0 22.7 51.1 23.0 11.6 8.8 9.8 12.7 9.5 14.9 15.3 13.4 12.5 6.4 15.9 13.2 14.0 2.3 14.1 12.1 20.2 9.0 4.5 25.2 32.6 27.7 26.0 26.0 22.3 26.9 23.0 28.5 33.8 101.3 209.4 134.1 138.3 285.5 99.2 532.6 145.2 179.3 205.9 326.2 47.1 126.1 122.7 191.6 558.1 145.8 91.2 116.8 202.2 178.1 139.3 179.5 165.5 428.2 118.4 73.1 151.6 136.2 112.7 88.6 115.3 122.6 135.0 171.3 133.7 81.8 227.8 86.3 165.2 160.8 108.6 271.7 161.7 293.6 551.3 283.8 151.7 127.0 125.6 200.5 ELAC1 D29 ENSG00000141642 "ElaC ribonuclease Z 1" Q9H777 18 50967991-50988121 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040867, HPA066483" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA040867: AB_10697716, HPA066483: AB_2685675" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "unprognostic (6.95e-3)" "unprognostic (1.75e-2)" "unprognostic (8.61e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (3.03e-3)" "unprognostic (5.87e-2)" "unprognostic (2.82e-3)" "unprognostic (3.67e-3)" "unprognostic (6.36e-2)" "prognostic favorable (8.43e-8)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" 8.7 15.0 7.7 7.7 9.7 3.3 9.4 7.1 11.9 8.0 9.1 12.8 12.1 7.6 11.3 20.1 7.5 10.0 9.6 7.2 7.3 8.3 12.4 15.2 7.6 11.2 7.6 7.2 8.8 19.5 17.1 15.7 12.3 8.7 9.9 10.8 13.7 20.1 12.2 6.8 7.7 11.7 8.3 7.1 10.8 10.1 16.7 3.9 10.1 15.6 7.0 9.9 8.7 6.6 14.2 12.4 7.8 9.1 16.1 15.7 8.1 7.0 4.9 13.0 11.0 14.6 6.2 5.5 7.8 10.3 7.3 5.2 1.8 6.7 5.5 5.4 7.2 5.8 7.2 4.0 8.2 5.0 12.0 1.1 6.8 1.8 1.3 8.6 17.0 4.9 7.8 6.6 3.9 9.1 5.8 7.6 8.0 6.9 13.8 12.9 3.2 5.9 5.1 6.5 6.0 2.2 6.7 4.6 10.2 8.5 3.0 7.7 8.8 6.4 1.1 12.4 5.7 6.0 13.1 6.7 9.6 5.0 2.8 5.2 12.9 10.8 7.3 8.9 5.7 12.0 4.1 7.8 7.8 13.2 9.1 14.6 14.2 12.7 12.9 12.4 13.6 12.4 15.7 0.9 16.1 8.7 10.4 10.0 8.1 7.7 9.7 7.1 11.9 7.3 8.3 7.6 7.2 8.7 3.9 6.0 6.2 8.5 4.6 2.2 7.1 5.6 5.1 10.7 3.4 3.5 2.0 20.4 16.6 12.5 16.4 5.8 8.8 0.0 12.0 13.8 5.4 6.3 8.1 13.9 13.7 4.8 9.9 8.0 6.6 12.8 4.6 5.2 5.0 10.8 8.3 10.8 10.1 7.0 6.7 17.7 7.4 0.0 5.9 27.3 9.4 3.0 15.8 5.0 9.5 3.4 ELAC2 "FLJ10530, HPC2" ENSG00000006744 "ElaC ribonuclease Z 2" Q9BQ52 17 12992391-13018187 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Disease mutation, Primary mitochondrial disease, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 96.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019535 Approved Enhanced Nucleoplasm NA NA Nucleoplasm "HPA019535: AB_1848106" "unprognostic (4.24e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.24e-6)" "unprognostic (8.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-1)" "unprognostic (5.31e-3)" "unprognostic (3.09e-1)" "unprognostic (5.31e-3)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (8.09e-2)" "unprognostic (3.70e-2)" 20.3 35.9 15.2 17.2 23.5 13.8 18.6 16.9 30.0 17.5 21.2 24.6 17.9 15.8 22.1 13.1 25.9 19.5 19.6 28.1 14.2 14.3 23.5 34.8 14.2 19.4 18.2 19.5 20.3 24.5 27.5 14.0 21.2 20.5 20.7 25.1 19.4 19.1 26.2 49.2 20.7 18.7 26.6 15.6 25.5 22.8 29.5 17.1 28.1 20.7 20.1 25.9 23.0 16.3 19.9 23.5 9.4 20.4 24.0 25.1 20.9 14.7 23.6 16.3 18.2 13.1 12.8 9.9 16.2 13.0 26.5 17.9 18.9 7.9 26.8 17.7 15.4 10.0 20.0 29.6 18.8 26.6 13.9 29.9 15.7 18.4 12.4 9.7 13.4 21.7 11.4 16.0 20.6 19.2 11.9 18.5 15.9 21.4 8.2 20.1 13.1 23.6 13.4 13.5 28.3 15.8 16.6 28.0 16.8 15.0 13.3 8.4 12.3 20.6 13.4 8.3 96.8 13.3 5.8 18.0 32.8 10.9 13.0 23.8 5.1 9.5 10.8 13.0 14.3 11.9 9.4 14.7 9.3 21.4 20.1 23.0 19.9 20.7 21.3 23.5 17.4 21.5 19.2 2.2 24.0 20.4 13.3 25.1 20.9 15.2 23.5 16.9 30.0 14.2 14.3 18.2 19.5 20.5 17.1 6.0 13.3 13.7 8.6 9.2 10.1 22.9 15.3 10.7 5.7 15.7 2.0 52.4 16.6 22.1 5.2 12.0 10.9 0.0 22.4 24.6 15.4 8.8 9.2 21.8 24.4 11.1 8.1 12.3 14.6 4.2 9.8 10.2 13.5 18.0 10.0 13.8 23.0 16.1 20.1 15.6 10.9 51.8 13.3 25.0 27.4 12.7 28.0 13.8 16.6 7.1 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 244.3" "Cell type enhanced" "Detected in some" 9 "Basal keratinocytes: 7.7;Fibroblasts: 5.7;Kupffer cells: 5.6;Leydig cells: 5.8;Melanocytes: 6.8;Suprabasal keratinocytes: 6.5" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 3.2;neutrophil: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 6.9;monocytes: 3.2" "Cell line enriched" "Detected in some" 65 "THP-1: 197.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015409, HPA066836" Enhanced "Secreted to blood" NA NA 59000 "CAB015409: AB_831596, HPA066836: AB_2685733" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 1.5 0.3 0.1 0.3 0.1 244.3 1.6 0.2 0.6 0.3 0.6 0.7 0.0 0.3 0.3 0.7 0.5 0.6 0.8 31.2 0.0 0.0 0.3 1.5 17.8 1.6 0.0 0.0 0.3 1.8 0.3 0.4 4.7 0.5 1.4 0.3 1.0 0.7 0.3 1.1 2.1 0.5 0.5 0.0 22.5 0.5 0.3 0.0 23.0 2.3 0.9 0.3 1.0 0.2 0.0 0.0 6.9 3.2 0.0 0.5 11.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 3.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 11.2 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 5.6 0.0 5.8 0.0 6.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.7 0.2 0.0 6.5 0.0 0.0 0.0 0.0 ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase Q8NFI3 17 79074939-79088599 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 51.4" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021551 Enhanced Approved Centrosome,Cytosol No No Cytosol Centrosome "HPA021551: AB_1848156" "unprognostic (7.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.65e-2)" "unprognostic (6.16e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-3)" "unprognostic (9.62e-2)" "unprognostic (4.09e-2)" "unprognostic (9.07e-2)" "unprognostic (7.00e-3)" "prognostic favorable (2.60e-4)" "unprognostic (4.79e-2)" "prognostic unfavorable (8.97e-6)" "unprognostic (8.38e-3)" "unprognostic (6.03e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.73e-5)" 10.0 10.1 9.5 20.7 18.4 8.9 11.4 7.0 13.9 10.9 15.1 12.4 8.8 20.3 11.4 6.8 6.5 10.6 8.6 10.3 9.3 5.8 9.2 10.2 10.1 10.7 16.8 8.5 16.3 9.3 11.3 9.8 8.1 13.6 12.3 12.5 10.7 12.1 9.6 35.4 11.9 17.3 7.3 11.9 24.9 11.4 3.9 14.0 8.1 13.6 7.0 9.1 17.5 51.4 0.2 0.7 0.0 1.1 0.0 2.1 0.6 4.5 9.8 3.4 6.3 3.6 1.5 6.6 3.5 1.8 2.9 2.0 5.2 5.0 0.0 4.2 3.5 4.8 6.8 5.4 3.8 1.6 2.7 7.3 4.1 10.0 3.1 2.7 4.7 7.8 4.1 5.3 2.5 2.8 5.6 3.0 8.9 5.9 2.9 1.8 3.9 0.4 4.5 1.5 9.5 8.8 8.6 11.7 3.0 1.5 12.9 2.9 5.7 5.6 25.9 2.6 5.3 9.1 4.4 3.9 5.6 4.2 4.8 3.4 6.9 1.2 2.0 2.3 8.7 4.0 0.0 0.7 0.0 0.0 1.1 0.9 0.0 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.5 0.6 2.1 0.6 9.5 18.4 7.0 13.9 9.3 5.8 16.8 8.5 13.6 14.0 0.0 13.6 6.4 3.8 3.9 10.7 4.8 7.6 0.0 6.8 10.4 33.4 4.2 0.0 3.5 1.5 6.5 16.4 0.0 3.6 3.8 4.8 7.4 4.7 10.6 7.5 7.9 25.1 9.8 10.8 1.0 3.1 8.2 0.0 5.4 15.9 5.6 2.5 11.5 1.8 1.7 24.7 12.9 6.0 2.2 1.4 5.1 5.6 5.7 18.8 4.1 ENOPH1 "E1, MASA, mtnC" ENSG00000145293 "Enolase-phosphatase 1" Q9UHY7 4 82430562-82461091 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004985, HPA044607" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA 140000 Nucleoplasm "Nuclear bodies" "CAB004985: AB_426046, HPA044607: AB_2679019" "unprognostic (6.64e-3)" "unprognostic (3.05e-1)" "unprognostic (6.77e-3)" "unprognostic (1.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.68e-3)" "prognostic unfavorable (1.74e-5)" "unprognostic (9.99e-3)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (1.59e-1)" "unprognostic (2.05e-1)" "unprognostic (9.30e-3)" "unprognostic (3.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.52e-3)" "unprognostic (3.52e-2)" 10.2 15.4 43.4 12.1 37.1 14.3 16.3 22.9 38.8 13.8 12.7 34.7 5.1 12.2 10.5 23.3 13.5 10.4 9.0 11.1 44.2 34.9 20.8 13.3 11.1 16.0 47.5 26.4 12.9 14.6 17.8 11.7 17.7 31.0 17.2 15.3 8.9 11.4 11.9 9.8 13.1 11.0 11.1 66.2 12.8 13.2 6.1 29.4 14.2 18.0 8.2 18.6 10.7 9.5 13.0 14.1 4.3 10.4 14.4 20.2 12.2 18.5 12.3 22.1 13.7 13.5 13.3 24.2 21.6 14.5 19.8 17.7 22.4 20.8 37.0 22.7 16.4 21.7 10.0 29.2 27.4 35.9 22.2 13.6 22.4 12.0 29.8 21.9 37.0 19.4 12.8 29.1 20.7 24.6 14.3 20.0 23.5 28.9 20.4 25.8 23.9 40.8 22.0 20.3 47.0 10.0 29.1 33.9 20.1 32.3 18.4 31.3 19.1 12.3 37.3 27.5 20.7 16.8 17.9 14.7 24.6 18.3 24.3 28.5 23.5 20.1 46.1 15.9 23.1 33.0 3.4 8.7 4.3 14.4 10.4 18.0 13.0 17.3 16.5 12.7 11.0 20.2 16.2 0.7 14.4 8.8 14.1 18.4 12.2 43.4 37.1 22.9 38.4 44.2 34.9 47.5 26.4 31.0 29.4 14.9 8.0 28.1 32.4 60.9 36.5 11.3 12.7 12.0 15.9 12.2 15.7 71.0 74.6 41.8 4.1 24.5 12.6 0.0 22.6 47.0 29.3 32.2 38.0 10.2 49.6 27.0 28.2 13.5 22.1 4.1 24.5 27.7 37.1 45.1 21.1 46.8 34.7 8.6 22.6 42.5 27.7 12.9 30.9 6.8 22.6 56.0 39.0 34.8 25.8 31.0 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.1;kidney: 63.8" "Cell type enhanced" "Detected in many" 14 "Proximal tubular cells: 153.4;Sertoli cells: 155.2;Smooth muscle cells: 60.8;Syncytiotrophoblasts: 49.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.2;HEK 293: 11.4;MOLT-4: 2.7;SuSa: 8.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA005128 Enhanced NA NA 37000000 "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 5.8 1.0 0.4 0.4 0.6 0.0 2.8 0.3 1.0 1.1 54.4 0.4 0.7 11.1 5.3 2.4 0.8 1.4 1.1 2.3 0.5 0.3 63.8 14.5 2.7 0.5 0.4 0.3 1.0 1.0 33.3 0.8 4.4 0.5 1.4 0.0 0.8 0.6 0.5 2.3 0.4 165.1 3.1 0.5 4.7 0.7 0.4 0.4 1.4 2.4 2.0 0.4 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.1 0.2 4.2 0.6 0.0 0.2 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.5 2.7 0.5 0.5 0.1 0.0 0.2 0.0 0.4 0.0 0.4 0.1 0.2 0.0 2.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.3 1.0 0.5 0.3 0.4 0.3 0.5 0.4 0.0 1.3 0.0 0.1 1.4 0.0 3.3 0.0 0.0 0.0 10.4 0.0 33.0 14.9 0.0 0.4 1.4 2.6 0.0 0.0 2.7 19.7 0.1 0.0 24.1 2.4 0.0 1.7 1.8 0.3 0.0 0.6 0.6 0.0 0.0 0.8 0.0 0.0 0.8 0.4 153.4 0.0 155.2 60.8 0.0 0.2 0.9 49.0 1.3 1.1 0.1 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease mutation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 12 "Hepatocytes: 80.9;Peritubular cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "NK-cell: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 23.1;LHCN-M2: 13.8;U-138 MG: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" NA NA 2500000 "CAB032904: AB_2099635, HPA062066: AB_2684674" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" 17.2 2.1 0.5 1.9 0.5 0.0 30.5 0.6 0.4 8.5 2.8 1.6 8.3 1.1 25.7 7.1 1.5 6.4 2.6 1.9 0.5 0.7 10.9 19.4 2.0 0.7 1.1 0.0 7.3 17.5 22.2 27.0 28.9 0.8 3.3 1.2 13.4 5.4 6.5 2.1 1.7 2.6 6.8 2.0 1.2 1.7 4.6 0.3 2.0 13.2 6.9 1.4 3.2 7.7 0.6 2.2 1.4 0.3 4.6 1.7 0.1 0.0 0.8 0.8 0.0 23.1 3.6 0.0 6.0 6.1 2.3 6.4 2.6 0.7 0.0 0.5 3.8 4.8 0.0 0.8 0.1 9.9 0.2 1.1 0.0 0.7 7.7 0.7 0.0 2.8 5.9 0.2 6.4 0.2 2.7 2.8 0.5 0.0 1.2 13.8 1.6 0.0 0.0 5.2 1.0 0.9 0.0 6.7 0.1 0.1 0.3 2.3 0.0 0.1 0.8 2.7 4.0 2.5 0.0 1.8 18.5 0.7 1.3 5.8 2.2 0.0 0.0 8.4 0.0 2.3 1.4 0.2 0.3 0.3 0.2 1.7 0.3 0.3 0.3 2.2 0.6 0.3 0.3 1.0 4.6 0.3 0.3 0.2 0.1 0.5 0.5 0.6 0.4 0.5 0.7 1.1 0.0 0.8 0.3 0.0 1.7 1.5 10.5 1.3 4.0 2.8 5.1 0.0 0.0 1.8 0.0 2.0 5.0 0.1 3.9 1.9 7.7 0.0 8.8 1.3 25.4 3.4 0.0 80.9 4.3 1.6 0.0 2.5 3.3 4.7 23.3 1.3 1.7 0.0 8.6 4.4 7.9 3.5 65.7 15.6 0.3 12.9 10.5 1.4 1.3 1.1 5.1 0.0 1.7 1.6 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.7;placenta: 79.0" "Cell type enhanced" "Detected in many" 6 "Cholangiocytes: 38.2;Fibroblasts: 51.0;Hofbauer cells: 50.0;Intestinal endocrine cells: 51.9;Melanocytes: 43.9;Proximal tubular cells: 45.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 26.8" "Cell line enhanced" "Detected in some" "AF22: 25.2;ASC diff: 34.5;ASC TERT1: 73.7;BJ hTERT+: 42.4;fHDF/TERT166: 27.3;HSkMC: 33.8;U-2197: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Intracellular and membrane" NA NA 1100000000 "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 29.9 15.4 24.0 18.2 42.0 0.7 26.2 4.4 33.3 19.6 8.1 103.7 1.7 20.8 44.8 6.4 2.9 18.7 12.7 3.6 39.8 21.5 24.9 8.9 13.5 31.0 71.5 20.9 5.3 5.2 0.9 4.1 79.0 59.7 8.5 10.6 67.6 3.4 9.2 3.0 5.4 12.1 28.9 102.4 17.3 8.3 9.7 63.9 3.6 3.7 0.8 26.1 13.4 5.7 0.2 3.8 26.8 0.1 0.2 1.8 0.3 0.0 0.0 25.2 0.0 34.5 73.7 0.0 23.2 42.4 10.0 9.6 0.0 0.0 0.0 0.3 27.3 0.0 0.0 0.5 0.0 7.1 1.8 0.7 0.0 0.0 0.6 15.4 0.0 0.1 33.8 0.2 20.4 1.0 0.1 0.1 0.0 0.0 4.1 0.5 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 20.3 0.4 24.4 0.1 0.2 0.0 0.0 17.1 0.1 0.5 26.8 0.1 5.2 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.0 1.8 0.6 0.3 0.2 0.0 3.8 0.0 0.3 24.0 42.0 4.4 33.3 39.8 21.5 71.5 20.9 59.7 63.9 11.9 5.1 3.2 0.5 9.4 1.1 1.2 38.2 6.7 1.2 1.8 0.0 3.4 1.7 0.0 34.3 16.3 0.9 0.0 0.0 1.5 51.0 0.1 5.8 0.4 50.0 0.0 51.9 19.0 12.5 3.6 2.8 8.9 43.9 0.0 0.6 3.3 1.2 0.3 3.2 45.6 1.2 0.0 5.1 1.1 0.4 4.5 5.4 0.5 0.6 0.9 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 29.0;intestine: 45.4;seminal vesicle: 70.7" "Cell type enhanced" "Detected in many" 20 "Enterocytes: 9.0;granulocytes: 33.7;Proximal tubular cells: 8.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 74 "basophil: 18.2" "Lineage enriched" "Detected in single" 74 "granulocytes: 18.2" "Group enriched" "Detected in some" 18 "HEL: 5.2;Hep G2: 17.0;HMC-1: 7.6" "Low region specificity" "Detected in some" HPA043772 Enhanced "Secreted - unknown location" NA NA 480000 "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 0.8 7.9 0.5 2.0 0.5 0.0 4.0 2.1 0.4 19.0 18.5 0.2 29.0 9.3 6.2 7.2 0.5 2.3 1.8 0.2 0.4 0.7 11.9 2.7 1.7 0.2 0.5 0.2 0.9 0.2 0.0 0.5 0.4 0.2 3.7 4.8 0.6 14.9 70.7 0.2 0.8 45.4 1.9 0.4 0.5 0.7 1.0 0.2 4.1 0.5 1.2 0.5 0.9 1.2 0.0 0.0 18.2 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 5.2 0.0 17.0 0.0 0.1 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.5 2.1 0.4 0.4 0.7 0.5 0.2 0.2 0.2 0.0 1.4 0.0 2.8 0.0 0.0 0.2 0.0 2.7 1.2 0.0 0.0 0.0 1.7 0.0 1.3 0.3 9.0 0.0 0.0 0.0 0.5 4.6 33.7 1.7 0.1 0.0 0.0 0.6 0.6 0.0 1.1 0.2 1.7 0.0 1.1 0.0 0.0 2.3 0.7 8.2 0.0 0.0 0.0 1.8 0.8 0.5 0.1 0.5 5.2 1.1 ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129993-46146699 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 1: 71.5;Ciliated cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 15.0;U-266/84: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved NA NA "HPA016594: AB_1848171" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (8.13e-2)" "unprognostic (5.51e-3)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (8.51e-2)" "unprognostic (4.36e-1)" "prognostic favorable (6.95e-7)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (2.56e-1)" 12.7 12.5 14.8 6.2 21.9 30.2 14.3 10.1 20.6 9.8 10.5 19.3 31.9 9.5 3.8 10.9 4.8 9.9 7.3 12.9 19.8 15.7 16.8 9.0 17.9 6.9 30.8 15.6 3.4 10.4 22.2 14.1 3.2 23.9 15.0 11.6 7.1 17.5 30.8 20.9 3.6 8.7 8.6 43.2 11.5 12.3 7.1 22.2 4.8 11.3 7.3 5.6 8.0 5.9 3.1 1.8 0.9 2.7 4.6 11.0 3.1 0.0 0.7 0.5 1.0 0.0 0.0 0.0 1.1 1.1 2.7 0.2 1.2 9.0 10.0 8.8 1.4 6.8 0.1 2.8 0.4 0.5 12.0 7.5 5.5 0.0 0.0 0.4 6.8 10.2 1.4 0.0 0.0 0.0 0.7 0.9 7.1 0.0 0.0 1.0 1.1 5.0 0.6 1.8 11.1 0.3 3.8 1.8 3.7 5.7 1.1 12.3 0.0 0.0 1.9 0.0 2.9 5.1 2.8 0.0 0.0 4.7 0.2 7.4 15.0 17.1 3.4 7.1 0.0 0.9 0.0 0.4 0.9 11.0 1.3 6.4 3.1 4.1 7.9 1.7 1.5 4.0 7.0 0.3 4.6 2.7 1.8 1.4 3.1 14.8 21.9 10.1 20.6 19.8 15.7 30.8 15.6 23.9 22.2 71.5 24.8 5.1 2.8 0.8 8.7 16.9 10.2 57.6 38.7 27.9 13.7 0.3 0.0 13.0 12.6 6.7 16.0 0.0 10.7 0.2 3.5 18.9 15.1 7.3 5.4 25.4 15.1 1.8 15.8 21.4 1.1 10.5 3.3 22.6 14.4 23.1 8.0 16.5 10.6 11.4 6.1 0.0 4.2 8.6 8.7 0.5 0.2 13.8 8.9 6.8 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;kidney: 30.8" "Group enriched" "Detected in some" 5 "Peritubular cells: 33.2;Proximal tubular cells: 21.8" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HDLM-2: 1.9;Karpas-707: 6.4;SH-SY5Y: 7.3;U-266/70: 6.0;U-266/84: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 68000 "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.5 0.6 2.0 1.1 8.0 1.1 1.0 1.7 6.7 0.5 1.3 35.2 0.4 2.0 0.5 6.9 1.3 0.5 0.8 0.5 5.4 3.5 30.8 0.4 0.6 1.1 26.1 3.3 13.7 0.3 0.3 4.1 0.4 19.5 2.7 1.3 7.7 0.9 6.9 0.4 0.5 2.5 0.4 28.2 1.2 1.5 2.7 14.0 0.0 0.5 0.0 3.1 0.9 0.7 0.9 0.8 2.2 0.9 1.5 0.6 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 1.9 0.0 0.7 0.3 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.4 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.4 0.0 0.2 7.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.2 0.1 0.0 0.1 6.0 3.2 0.1 0.1 0.1 0.0 2.2 0.9 0.6 0.5 0.5 0.6 0.7 0.4 0.3 0.1 0.9 0.4 0.5 1.7 1.5 0.3 0.8 0.5 0.1 2.0 8.0 1.7 6.7 5.4 3.5 26.1 3.3 19.5 14.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 3.3 0.9 0.8 0.2 0.0 0.0 0.2 0.0 0.2 0.1 5.7 0.0 0.2 0.0 0.0 0.0 0.6 0.0 3.7 0.0 1.7 1.8 0.0 0.0 0.0 0.0 33.2 21.8 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730919-79742222 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 71.1" "Group enriched" "Detected in some" 5 "Hepatocytes: 8.5;Proximal tubular cells: 7.3" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 2.9;Karpas-707: 5.2;U-266/70: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024603 Approved "Intracellular and membrane" NA NA 440000 "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.3 0.1 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95869695 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 59.4" "Cell type enhanced" "Detected in many" 8 "B-cells: 45.3;Endothelial cells: 46.6;Kupffer cells: 77.1;Macrophages: 80.4;monocytes: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 37.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HDLM-2: 57.3;Karpas-707: 47.1" "CAB002494, HPA014067" Enhanced Uncertain Microtubules NA NA Microtubules "CAB002494: AB_563557, HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favorable (7.89e-4)" "unprognostic (5.09e-2)" 10.4 7.5 7.4 16.2 8.4 15.6 8.8 7.6 6.9 18.9 12.7 13.1 8.7 5.8 59.4 12.8 13.2 15.6 22.2 6.8 7.4 7.4 6.2 3.9 14.8 14.5 8.5 4.9 10.3 2.8 3.0 4.3 24.0 9.9 14.7 9.1 10.8 6.7 12.7 3.3 5.5 12.2 37.2 17.9 25.3 7.5 5.4 7.2 3.5 13.4 12.5 21.1 25.2 12.4 6.0 11.8 37.4 15.2 0.5 5.1 4.6 0.1 0.3 0.9 0.8 0.0 0.0 0.5 0.5 0.4 0.0 0.0 0.5 0.1 1.0 0.6 0.0 1.4 0.3 0.0 0.0 0.0 57.3 0.7 0.6 0.4 0.7 0.0 1.5 0.2 0.0 0.0 0.2 0.0 0.3 7.5 0.3 0.6 47.1 0.0 0.6 0.4 1.5 0.6 0.6 0.2 2.4 0.4 0.7 0.5 0.2 0.7 1.1 0.3 1.1 0.8 0.6 0.5 1.6 0.8 0.4 0.2 0.6 0.6 6.7 0.9 0.0 0.6 3.1 0.2 0.1 15.2 37.4 0.1 10.7 0.3 6.0 0.6 0.3 11.8 4.6 0.1 0.1 26.7 0.5 2.4 0.7 5.1 4.6 7.4 8.4 7.6 6.9 7.4 7.4 8.5 4.9 9.9 7.2 0.0 1.4 45.3 0.3 7.9 1.4 8.5 0.0 1.4 1.2 1.8 2.0 0.4 1.7 0.0 5.9 46.6 0.0 0.0 1.8 1.7 8.7 0.4 3.5 0.0 23.2 0.0 0.0 11.6 77.1 6.1 0.6 80.4 15.1 46.9 0.0 0.7 0.2 0.2 2.8 0.3 0.7 6.5 32.0 6.2 4.3 9.8 13.2 14.6 0.4 0.2 ENTPD3 "CD39L3, HB6, NTPDase-3" ENSG00000168032 "Ectonucleoside triphosphate diphosphohydrolase 3" O75355 3 40387156-40428619 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 26.2;pancreas: 37.3" "Group enriched" "Detected in many" 4 "Exocrine glandular cells: 19.8;Pancreatic endocrine cells: 5.7;Sertoli cells: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "plasmacytoid DC: 7.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.4" "Cell line enhanced" "Detected in some" "HaCaT: 3.8;HBEC3-KT: 12.7;hTCEpi: 8.6;RT4: 18.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (2.75e-2)" "unprognostic (9.84e-3)" "unprognostic (2.27e-2)" "unprognostic (2.04e-1)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (8.40e-2)" "unprognostic (9.88e-3)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (3.25e-1)" "unprognostic (6.53e-2)" "unprognostic (5.99e-2)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" 4.6 2.2 5.7 1.7 25.9 0.5 2.1 5.4 15.8 26.2 3.3 0.6 1.9 1.7 4.0 4.4 7.5 1.3 3.6 1.4 4.9 6.3 3.6 0.5 4.8 0.9 4.0 6.3 2.6 37.3 1.7 4.2 2.9 14.5 5.3 3.6 2.8 21.2 5.1 1.7 3.2 1.6 2.5 1.7 5.1 8.8 1.3 4.8 0.0 7.0 5.6 4.8 13.7 2.9 0.5 7.4 1.4 0.3 0.9 0.8 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.1 3.8 0.0 12.7 0.3 0.7 0.4 0.7 0.5 0.2 0.0 0.0 0.0 0.1 8.6 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.0 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 0.3 1.6 18.3 1.9 0.4 0.8 1.4 0.3 0.4 0.7 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.4 0.0 1.1 0.1 0.1 1.4 0.2 0.0 0.2 0.3 0.8 0.3 0.2 0.3 0.0 0.5 0.6 0.6 0.0 0.9 0.2 7.4 0.6 0.1 5.7 25.9 5.4 15.8 4.9 6.3 4.0 6.3 14.5 4.8 3.0 3.4 0.0 1.0 2.1 0.0 0.4 0.0 1.4 2.3 0.0 0.0 0.0 0.0 2.0 0.3 0.0 0.0 0.0 19.8 0.0 0.2 2.3 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.3 5.7 0.0 0.7 0.0 0.6 19.4 3.1 0.3 0.1 1.9 0.0 0.0 0.0 3.7 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 28000 Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 15.0 21.9 19.8 25.7 15.3 20.3 27.4 15.2 18.5 14.7 15.7 17.0 18.8 17.9 13.3 12.7 14.4 21.0 14.5 12.8 13.0 14.4 19.9 26.0 16.2 12.2 14.7 26.5 30.4 25.2 19.3 20.6 17.6 20.2 18.0 19.5 13.7 14.9 12.2 26.1 16.1 14.5 26.9 19.1 18.7 15.8 17.0 15.8 9.3 30.7 16.7 16.7 9.7 8.0 15.9 9.5 4.4 10.7 6.8 9.3 12.9 16.3 11.2 14.2 18.1 16.6 15.0 14.3 10.2 16.0 18.5 12.5 15.9 10.9 15.1 15.7 11.4 7.3 13.6 19.6 3.8 5.1 8.4 8.0 6.4 11.6 4.4 16.7 11.1 16.6 13.5 14.5 24.9 14.6 12.4 5.8 14.6 17.2 4.2 6.4 5.4 9.5 12.0 4.7 6.4 16.3 4.8 13.0 11.1 13.0 12.4 5.6 8.2 11.0 33.9 6.0 6.3 18.0 18.6 18.4 20.8 11.0 11.7 4.9 20.7 24.9 5.3 18.6 14.9 6.0 13.7 8.5 9.5 10.0 9.7 8.3 9.1 8.0 6.7 10.7 8.3 15.9 4.4 6.9 7.3 6.5 6.8 15.0 19.8 20.3 27.4 14.5 12.8 16.2 12.2 20.6 15.8 17.9 34.6 17.1 9.5 5.8 30.2 20.4 7.6 14.7 28.4 14.0 13.7 12.6 0.0 13.8 6.9 13.7 17.8 23.3 14.7 13.0 12.7 14.2 16.3 10.5 10.5 44.5 16.6 11.1 11.0 15.7 6.6 15.2 11.8 12.6 15.2 18.9 18.1 11.9 8.1 3.7 34.2 12.9 12.3 20.7 21.1 4.8 16.9 15.0 10.5 13.9 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5" O75356 14 73958010-74019399 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 52.0;kidney: 43.1;liver: 71.4" "Cell type enhanced" "Detected in many" 8 "Enterocytes: 99.9;Hepatocytes: 120.9;Mucus-secreting cells: 67.4" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 15.0;eosinophil: 8.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Cell line enhanced" "Detected in all" "RT4: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5000000 "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 3.0 3.6 2.8 9.4 3.8 1.7 3.5 3.0 4.0 2.4 25.8 5.8 3.1 19.3 3.0 2.7 4.5 2.4 6.6 2.6 2.8 2.3 43.1 71.4 2.3 1.3 3.5 2.3 3.3 5.9 1.8 2.7 2.2 5.5 10.2 29.6 3.2 4.7 1.5 3.8 2.7 52.0 3.9 5.5 3.2 11.8 4.5 2.5 2.1 2.7 3.0 3.3 9.5 3.0 1.6 1.6 15.0 2.1 0.6 2.5 1.2 5.4 4.4 5.0 9.3 10.0 9.5 5.8 5.7 4.7 3.8 4.4 3.3 6.6 6.2 2.9 7.8 3.7 6.5 5.0 8.3 4.3 5.2 2.4 4.6 3.2 18.1 9.7 2.7 5.4 7.7 8.4 5.4 11.2 5.4 7.6 10.2 5.1 9.4 5.6 7.7 3.1 3.3 1.5 4.9 9.6 3.5 4.8 3.0 6.7 34.5 3.6 3.7 9.7 7.7 5.5 4.0 11.1 2.5 6.4 7.7 8.0 4.6 4.2 6.1 9.5 5.0 4.9 5.1 6.9 15.0 1.2 8.3 2.5 2.1 1.3 1.3 1.3 1.7 1.6 1.6 2.1 2.1 0.2 0.6 1.3 0.8 1.4 1.2 2.8 3.8 3.0 4.0 2.8 2.3 3.5 2.3 5.5 2.5 14.9 7.9 6.7 4.8 3.3 6.1 4.8 12.7 5.3 10.3 7.0 3.9 6.4 21.6 5.1 13.9 5.4 99.9 0.0 11.3 5.7 4.9 39.5 1.1 120.9 5.5 9.5 15.5 11.6 7.0 8.7 2.6 5.1 5.0 6.4 67.4 4.8 7.4 54.7 5.3 50.1 12.0 12.9 4.1 20.1 18.3 3.0 2.7 4.9 41.0 12.3 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6 (putative)" O75354 20 25195693-25226729 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 76.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 18000 "Golgi apparatus" "HPA015491: AB_2669200, HPA069555: AB_2686152" "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 12.7 19.7 21.8 11.3 46.5 6.7 12.8 33.1 49.1 9.8 31.3 12.1 12.8 31.6 9.4 10.1 9.0 12.5 18.3 27.5 24.9 25.0 13.4 12.9 11.0 7.4 15.1 29.2 16.1 25.6 11.7 20.5 13.2 15.4 25.5 24.5 9.0 36.8 9.7 15.1 6.8 32.2 9.9 8.2 8.3 24.7 16.1 10.5 9.4 10.4 6.1 8.3 10.2 7.1 7.2 17.1 3.0 16.0 8.8 17.9 12.9 20.7 32.9 9.0 17.3 11.4 14.3 19.4 17.1 12.4 14.8 13.7 17.6 16.1 12.6 25.8 16.4 29.0 27.2 11.0 26.0 9.9 7.7 9.8 10.2 5.0 39.7 17.1 13.6 15.8 13.4 14.5 18.7 14.2 10.9 11.9 12.3 13.3 22.0 11.0 19.9 12.7 8.4 5.7 17.3 25.8 7.2 28.2 28.8 18.6 13.0 14.4 7.5 4.7 28.9 76.8 8.7 21.1 11.5 12.8 17.3 18.0 14.2 20.1 13.8 11.1 5.5 12.4 9.0 32.5 0.0 16.0 3.0 12.7 10.7 17.9 6.1 11.4 10.4 17.1 7.2 12.2 10.6 0.7 8.8 4.8 12.0 10.6 12.9 21.8 46.5 33.1 49.1 24.9 25.0 15.1 29.2 15.4 10.5 17.9 31.6 13.4 14.5 8.8 16.7 4.3 28.1 8.1 7.9 17.4 9.8 53.2 8.3 33.5 18.1 5.8 66.6 0.0 35.1 18.5 10.3 22.0 3.5 13.0 22.9 23.8 32.6 17.2 15.4 46.1 19.0 16.9 10.1 17.2 55.2 3.9 28.8 57.5 39.6 11.0 7.9 6.5 5.9 3.2 9.1 5.3 50.0 8.4 60.2 10.1 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 48.1" "Group enriched" "Detected in some" 6 "Enterocytes: 107.0;Mucus-secreting cells: 160.6;Paneth cells: 49.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.1;OE19: 3.0;RPMI-8226: 8.8;T-47d: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.4 0.0 0.4 2.6 0.4 0.0 0.4 0.4 0.4 0.4 19.2 0.4 0.4 18.5 0.4 0.4 0.4 0.3 2.2 0.4 0.5 0.0 2.1 9.8 0.8 0.4 0.4 0.4 0.4 1.8 0.0 4.2 0.5 0.4 0.4 7.5 0.8 4.1 0.4 0.4 0.0 48.1 0.4 0.4 0.4 6.1 0.4 0.4 0.6 0.4 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.0 9.1 0.0 0.6 0.0 0.7 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 1.6 0.0 0.2 0.1 3.0 0.4 0.0 0.0 8.8 1.4 0.0 0.3 0.9 0.2 0.0 0.1 0.7 4.8 0.2 0.1 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.5 0.0 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.7 0.0 0.0 19.2 0.0 0.0 0.0 0.8 0.0 0.0 107.0 0.0 6.8 0.1 0.0 1.0 0.0 8.2 0.1 0.0 3.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 160.6 0.0 0.5 49.1 0.0 4.4 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 12.7 0.6 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810092-225845563 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4;liver: 265.0" "Cell type enhanced" "Detected in many" 12 "Hepatocytes: 721.1;Leydig cells: 288.2" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 6.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 157.2;SiHa: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 83000 "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 39.5 156.4 16.8 5.7 20.1 3.4 31.3 8.3 25.1 31.3 12.6 28.7 15.3 16.6 21.8 15.7 24.9 26.2 17.8 11.5 16.3 11.2 36.8 265.0 24.1 6.9 17.1 14.5 45.6 85.0 39.5 14.0 5.4 23.6 25.9 8.4 27.3 26.3 21.3 16.4 8.8 9.6 18.6 10.7 8.3 12.1 22.7 12.6 3.6 24.9 15.6 14.9 20.9 32.3 0.5 2.2 0.5 6.6 1.4 1.3 2.3 4.5 43.3 1.7 15.9 157.2 16.4 3.4 5.2 6.6 3.8 5.3 8.9 46.0 0.1 19.7 19.6 4.3 5.0 4.7 2.5 1.5 1.0 8.2 3.2 18.3 49.9 17.1 2.0 1.9 15.3 5.7 10.7 1.0 14.9 2.8 1.9 2.2 4.0 6.7 5.3 1.9 3.7 9.3 21.7 12.2 4.2 2.0 13.1 11.4 28.5 14.9 1.9 74.7 26.8 6.9 4.3 19.9 5.8 8.2 6.5 5.2 8.7 8.3 1.3 6.8 0.6 9.7 2.1 8.5 0.0 6.6 0.2 0.5 1.9 0.9 0.3 0.9 0.5 1.5 0.5 1.3 1.0 0.5 1.4 0.8 2.2 0.7 2.3 16.8 20.1 8.3 25.1 16.3 11.2 17.1 14.5 23.6 12.6 0.0 12.3 2.9 88.1 17.4 7.0 1.4 96.8 16.0 12.5 48.8 27.5 40.2 14.9 84.0 9.3 77.9 28.9 23.3 63.2 4.5 52.6 51.6 5.7 721.1 118.3 1.6 10.4 74.9 24.4 15.1 288.2 14.5 40.5 8.2 13.8 96.3 71.3 21.0 149.6 79.4 10.3 219.9 78.5 3.1 3.6 15.4 19.1 10.2 31.9 79.3 EPHX2 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490779-27545564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 83.9;liver: 87.6" "Cell type enhanced" "Detected in many" 7 "Distal tubular cells: 152.5;Proximal tubular cells: 198.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 39.2" "Lineage enriched" "Detected in many" 24 "T-cells: 39.2" "Group enriched" "Detected in many" 4 "JURKAT: 50.5;K-562: 17.8;OE19: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 720000 Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 4.8 25.1 4.8 14.3 6.0 0.4 8.3 5.6 3.3 7.6 56.2 6.1 21.8 29.8 10.3 15.1 15.2 11.3 9.4 7.8 4.1 4.8 44.2 87.6 4.6 5.0 5.8 3.2 11.4 25.3 11.6 14.6 2.9 10.5 17.9 15.6 13.3 18.0 22.7 8.5 11.5 83.9 13.1 4.5 3.5 6.7 5.4 3.9 45.7 7.5 13.2 11.7 7.0 7.4 1.6 0.0 0.0 0.0 1.4 39.2 7.6 5.3 3.6 2.3 2.9 0.1 0.0 1.7 0.4 0.3 0.2 0.0 2.8 3.6 0.0 2.1 1.3 1.2 3.8 0.4 0.9 0.1 0.0 1.7 7.9 0.4 8.7 1.3 0.0 1.6 3.2 3.9 0.0 0.4 0.9 0.1 50.5 17.8 0.0 0.0 1.6 5.1 0.2 3.7 36.3 6.2 0.0 0.0 0.1 3.2 0.8 1.9 5.9 4.3 5.2 5.2 1.8 7.9 1.5 0.0 0.0 1.4 0.6 0.0 4.6 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 4.0 1.6 12.5 4.5 0.0 0.9 39.2 18.0 0.0 1.4 0.0 0.0 9.4 7.6 4.8 6.0 5.6 3.3 4.1 4.8 5.8 3.2 10.5 3.9 6.0 13.4 4.7 14.5 10.5 33.3 21.0 15.3 24.1 10.3 26.2 74.6 18.1 152.5 4.7 6.3 6.0 93.2 0.0 5.7 2.6 7.2 27.0 5.7 98.6 1.8 31.8 22.4 10.4 3.5 2.4 27.6 0.8 5.0 2.8 54.7 84.9 4.3 74.7 17.7 198.6 56.3 0.0 12.0 1.5 7.0 15.9 6.9 5.7 88.0 6.7 EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.8;lymphoid tissue: 29.6;skin 1: 33.1;tongue: 39.6" "Group enriched" "Detected in many" 4 "Suprabasal keratinocytes: 37.9;Urothelial cells: 18.6" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "intermediate monocyte: 4.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 18 "dendritic cells: 2.8;monocytes: 4.9" "Cell line enhanced" "Detected in some" "EFO-21: 4.0;NTERA-2: 3.7;OE19: 12.9;SuSa: 5.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favorable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" 0.2 0.1 0.1 0.2 0.3 0.1 1.0 0.1 0.3 12.5 0.2 0.2 0.4 0.1 0.9 0.3 34.8 1.1 1.7 0.1 0.5 0.1 1.6 0.2 1.6 0.0 0.2 0.0 0.6 0.0 2.2 2.4 0.2 0.4 1.5 0.1 0.6 3.4 0.6 0.2 33.1 0.2 0.2 0.2 1.2 0.5 2.7 0.2 2.4 0.2 39.6 29.6 2.8 13.6 0.0 2.8 0.2 4.9 0.0 0.0 0.5 0.1 0.3 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.5 0.3 4.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.6 0.0 0.5 3.7 12.9 0.5 0.0 0.0 0.0 0.1 0.8 1.6 0.2 0.0 0.1 0.0 5.7 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.0 1.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 4.9 2.8 0.0 0.5 0.1 0.3 0.1 0.3 0.5 0.1 0.2 0.0 0.4 0.2 0.0 0.6 0.0 1.5 6.3 0.2 0.3 2.5 1.4 0.0 5.2 0.0 1.5 1.7 0.5 0.3 0.1 0.0 0.0 0.0 2.5 0.7 2.0 0.0 0.0 0.6 0.0 0.0 1.3 1.3 0.0 0.0 1.4 0.0 1.0 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 2.1 2.1 37.9 2.2 0.0 0.0 18.6 EPM2A "LD, LDE" ENSG00000112425 "EPM2A, laforin glucan phosphatase" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation, Epilepsy, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 23.5;Early spermatids: 28.2;Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 5.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 20.3" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm NA NA Nucleoplasm "HPA053643: AB_2797247, HPA055468: AB_2797252" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.4 6.0 8.8 1.9 9.0 2.2 3.6 4.0 8.9 3.9 11.1 8.6 2.5 3.4 4.8 4.8 8.9 4.3 3.9 19.4 9.6 8.7 8.0 5.7 3.5 3.4 11.9 5.5 5.9 2.9 5.5 3.3 2.0 9.6 6.2 3.4 5.6 3.1 9.2 60.9 2.4 3.3 13.9 13.6 2.5 4.6 3.3 7.1 3.7 4.2 15.7 2.9 10.4 6.0 1.4 1.0 0.3 1.4 5.4 2.4 1.0 1.1 1.7 3.3 6.3 8.2 2.5 1.4 3.0 3.5 2.8 3.4 1.5 1.7 20.3 2.5 3.5 3.4 1.8 1.2 1.3 2.5 7.9 1.7 3.3 2.4 2.5 5.0 11.3 2.0 2.1 6.8 1.7 0.6 3.7 2.0 4.8 1.4 5.2 3.5 2.6 7.5 2.4 3.4 3.0 1.7 4.3 3.0 5.9 2.5 1.7 6.1 6.1 5.3 3.2 7.0 3.1 1.8 6.5 4.3 2.8 1.4 2.6 2.3 3.8 3.8 8.2 2.4 2.7 4.4 0.0 0.1 0.1 0.4 1.4 1.1 1.3 1.1 0.9 1.0 1.4 1.2 2.4 0.3 5.4 0.3 0.9 0.2 1.0 8.8 9.0 4.0 8.9 9.6 8.7 11.9 5.5 9.6 7.1 6.0 1.0 3.2 0.8 0.8 7.9 23.5 5.1 2.7 3.4 1.8 5.9 0.7 10.0 0.9 28.2 1.5 0.3 0.0 2.0 0.6 1.2 1.3 2.3 5.8 2.0 28.6 1.2 1.3 1.5 14.1 2.8 3.1 6.8 0.0 1.5 7.5 1.1 1.1 2.1 6.3 6.7 0.0 2.0 1.6 1.3 0.4 0.3 0.0 1.0 0.3 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 7.4 15.6 11.4 10.6 17.7 6.7 7.1 9.5 23.8 9.4 8.1 11.7 7.8 7.9 11.7 6.0 6.7 10.0 10.1 7.9 9.4 9.1 8.7 13.2 6.5 9.9 8.2 10.5 9.5 13.1 12.9 10.9 7.2 14.0 8.2 6.4 12.5 9.5 11.8 15.9 10.7 7.1 11.2 5.3 9.7 8.3 17.2 7.8 10.8 10.2 5.1 8.3 9.3 6.6 7.8 17.2 5.0 13.9 11.3 9.8 8.7 12.6 6.2 12.9 18.1 7.7 9.1 6.8 18.0 12.4 23.3 17.9 14.3 8.7 4.5 10.3 17.5 8.5 6.5 9.0 15.1 8.9 10.9 14.8 7.7 11.7 15.1 16.3 12.2 13.6 10.5 2.4 26.6 15.1 13.0 13.5 13.0 18.6 5.1 16.0 6.1 7.1 8.1 5.9 11.6 10.9 13.8 9.2 3.8 6.7 11.2 7.5 8.2 16.0 11.3 6.4 10.2 10.7 16.2 17.5 22.3 12.2 9.4 40.0 11.9 6.8 6.5 6.6 7.4 9.8 0.0 13.3 5.0 7.7 13.9 9.8 7.8 7.4 7.4 17.2 5.8 7.1 7.4 0.4 11.3 10.9 8.3 7.4 8.7 11.4 17.7 9.5 23.8 9.4 9.1 8.2 10.5 14.0 7.8 6.0 4.3 3.6 3.9 5.6 0.0 6.0 10.2 6.7 5.7 5.2 0.0 9.4 11.6 7.6 4.1 3.8 2.9 0.0 7.0 10.0 6.8 3.5 0.0 11.5 9.8 0.0 6.9 9.2 7.3 2.2 6.1 4.6 3.3 1.8 7.8 0.0 6.2 3.5 7.4 11.3 0.0 0.0 5.2 33.8 11.0 5.0 4.0 2.9 7.7 3.3 ERCC3 "BTF2, GTF2H, RAD25, TFIIH, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294176 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "CAB037153: AB_796181, HPA046077: AB_2679527" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavorable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 17.4 20.0 26.1 23.8 28.9 20.5 21.0 35.9 32.0 22.1 19.4 19.7 17.1 11.5 21.6 15.7 19.1 23.6 20.4 20.4 23.2 18.8 17.5 17.4 19.4 23.1 19.7 25.8 23.3 22.4 32.0 26.4 16.3 21.5 20.1 17.1 18.3 18.0 21.8 30.1 19.7 17.3 26.1 16.0 24.5 17.4 39.5 20.1 24.1 19.3 15.8 25.9 22.4 20.8 11.8 13.9 7.2 9.7 18.8 16.2 11.7 22.2 15.3 19.0 20.1 21.1 14.5 23.5 20.5 26.6 33.2 32.2 23.4 16.3 16.9 17.0 18.7 21.5 20.0 28.9 21.6 28.9 26.4 25.9 21.2 18.7 24.6 15.7 18.4 23.1 15.0 20.3 38.3 16.4 21.2 21.3 22.2 20.6 11.1 20.9 22.0 26.2 19.8 27.6 14.5 23.9 21.6 21.8 14.0 18.5 20.8 23.0 24.8 17.5 26.7 26.8 22.7 14.4 21.1 16.9 20.0 22.9 18.1 24.3 19.9 38.8 26.5 17.7 8.9 21.3 6.6 9.5 7.2 16.0 9.7 16.2 11.5 11.8 13.5 13.9 11.8 15.8 10.9 3.1 18.8 7.9 11.3 16.1 11.7 26.1 28.9 35.9 32.0 23.2 18.8 19.7 25.8 21.5 20.1 20.8 13.4 8.2 8.1 6.8 0.0 10.5 5.1 32.1 22.7 7.0 0.0 15.9 1.7 12.0 3.5 14.3 4.9 0.0 13.1 10.3 12.0 6.2 9.3 7.8 12.5 0.0 5.8 12.3 12.6 3.1 15.3 9.2 8.5 12.6 8.2 0.0 12.9 5.8 12.0 7.0 0.0 12.9 8.5 34.7 27.5 8.3 12.2 13.8 9.9 5.6 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239047 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" 11 "Cholangiocytes: 2.5;Extravillous trophoblasts: 1.5;Spermatocytes: 1.7;Spermatogonia: 2.0" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "NK-cell: 5.3" "Lineage enriched" "Detected in many" 5 "NK-cells: 5.3" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No No Centrosome "Nucleoplasm, Cytosol" "HPA050492: AB_2681145" "prognostic unfavorable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.4 0.5 0.2 3.1 0.2 6.0 3.0 0.9 0.8 1.5 2.2 0.2 0.2 1.5 0.9 0.8 4.6 0.6 1.0 0.2 0.2 0.3 0.5 0.5 0.8 4.7 0.7 0.2 1.2 0.5 0.0 0.6 0.9 0.9 0.7 2.5 0.2 1.1 0.2 2.6 1.3 2.1 0.5 1.3 4.0 1.5 2.0 0.2 13.1 0.5 2.8 5.6 0.7 1.6 0.5 0.3 0.5 0.2 5.3 1.1 0.4 11.0 9.7 8.9 5.6 0.6 1.1 4.9 11.9 5.5 10.4 11.0 7.9 6.9 17.9 4.5 4.2 14.1 9.2 16.8 8.8 18.6 10.2 12.2 6.2 3.4 4.6 0.0 12.0 8.7 0.1 0.5 14.5 2.7 1.7 5.8 9.1 8.1 4.4 10.6 8.7 11.4 7.0 16.2 10.8 15.0 9.6 16.0 3.2 2.6 6.9 7.4 5.3 8.8 5.9 2.2 7.6 4.5 2.7 3.5 7.1 11.4 13.3 7.7 3.5 5.3 15.5 5.0 8.3 7.0 0.0 0.2 0.5 0.1 0.1 0.6 0.2 0.5 0.1 0.1 0.5 0.4 1.1 0.3 5.3 0.2 0.3 1.1 0.4 0.2 0.2 0.9 0.8 0.2 0.3 0.7 0.2 0.9 0.2 0.0 0.0 0.8 0.2 0.2 0.0 0.4 2.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.1 0.3 0.0 0.1 0.1 ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797232 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 16000000 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: AB_10697553" "unprognostic (3.05e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (7.66e-2)" "unprognostic (1.75e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.73e-2)" "unprognostic (3.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" 58.5 30.9 32.0 28.6 29.8 24.2 44.5 23.7 32.0 54.4 37.3 29.0 34.2 31.8 53.2 50.4 54.1 40.6 30.3 45.6 30.7 29.3 58.8 82.2 28.2 31.4 31.7 32.1 61.3 24.9 27.5 47.5 26.4 28.6 55.2 41.7 32.5 31.5 45.2 47.4 29.7 38.4 50.8 37.4 31.1 32.1 32.4 26.7 65.5 78.9 50.9 31.7 62.5 36.9 30.1 48.7 15.1 37.1 29.8 35.7 26.4 22.1 12.9 39.1 26.9 45.9 75.9 10.5 31.9 46.3 44.5 34.7 21.8 27.2 25.2 9.6 38.2 33.3 22.7 43.0 37.7 57.0 28.8 44.7 32.6 13.0 33.5 37.6 63.6 14.0 51.8 35.0 28.7 38.7 53.7 41.7 43.5 31.8 6.8 73.6 21.7 56.4 42.3 10.1 28.7 24.5 44.9 23.0 17.0 63.1 9.0 19.4 22.0 14.2 12.1 25.6 28.1 23.2 36.5 27.8 16.4 19.4 31.5 29.4 4.6 9.9 21.8 35.4 36.5 21.9 7.7 37.1 15.1 15.0 31.5 24.6 30.1 30.0 23.0 40.8 25.3 35.7 27.9 4.3 29.8 28.0 48.7 24.9 26.4 32.0 29.8 23.7 32.0 30.7 29.3 31.7 32.1 28.6 26.7 50.6 42.5 68.7 203.4 119.1 47.0 89.2 124.9 77.6 61.4 146.5 39.3 134.7 305.1 153.5 36.2 95.8 72.1 46.7 90.4 115.2 195.1 96.4 94.6 148.9 197.0 20.6 104.5 112.3 138.2 18.5 247.9 128.5 156.9 100.0 108.9 147.8 82.8 115.8 198.7 400.9 62.5 148.8 210.1 67.4 44.1 113.0 62.2 82.2 173.0 130.7 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.9;lymphoid tissue: 30.3" "Cell type enhanced" "Detected in some" 6 "Enterocytes: 4.1;Hepatocytes: 4.9;Proximal tubular cells: 5.6;Spermatocytes: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 1.8" "Lineage enriched" "Detected in single" 5 "T-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.7 0.4 0.2 7.1 0.4 7.2 0.3 0.2 0.5 3.9 2.3 0.4 0.8 4.2 0.6 0.7 17.9 0.2 0.5 1.0 1.1 0.1 1.0 0.9 0.7 4.1 0.2 0.2 0.3 0.2 0.0 0.2 3.0 0.6 0.4 1.5 0.6 2.6 0.2 0.2 2.7 4.4 0.5 0.2 3.0 0.8 10.9 0.3 30.3 0.3 2.5 7.8 0.7 6.2 0.0 0.0 0.4 0.1 0.0 1.8 0.0 12.6 12.9 13.8 11.3 0.3 1.2 8.5 8.3 4.2 14.3 9.1 7.0 11.1 22.8 4.6 3.4 8.4 10.5 16.0 4.9 7.5 7.1 16.2 15.3 11.7 5.3 0.0 9.6 12.7 0.4 0.3 8.3 4.1 1.4 7.3 11.3 20.5 20.6 4.2 13.1 15.0 8.2 11.2 7.5 7.0 14.1 14.8 9.5 2.0 5.3 10.0 7.7 7.0 10.3 5.4 6.8 17.0 6.4 3.3 7.2 14.0 6.0 11.4 15.3 14.2 15.4 4.1 9.1 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 1.8 0.0 0.2 0.4 0.2 0.5 1.1 0.1 0.2 0.2 0.6 0.3 0.0 0.0 0.0 0.1 0.8 0.0 0.8 0.0 0.0 0.0 3.5 0.0 0.7 0.0 0.2 0.6 0.4 4.1 0.0 0.0 1.9 1.0 0.3 0.0 4.9 2.1 0.0 3.4 1.3 0.6 1.1 0.0 1.3 0.0 0.0 1.2 0.0 1.0 0.2 0.4 5.6 0.0 0.0 0.4 6.5 2.7 0.5 0.2 0.0 3.1 0.5 EXD2 "C14orf114, EXDL2, FLJ10738" ENSG00000081177 "Exonuclease 3'-5' domain containing 2" Q9NVH0 14 69191511-69244020 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002906, HPA005848" Uncertain Approved "Intermediate filaments,Mitochondria" NA NA Mitochondria "Intermediate filaments" "HPA002906: AB_1078767, HPA005848: AB_1078768" "unprognostic (3.36e-2)" "unprognostic (1.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (9.91e-2)" "unprognostic (8.03e-2)" "unprognostic (2.46e-1)" "unprognostic (4.64e-2)" "unprognostic (8.97e-2)" "prognostic favorable (2.08e-9)" "unprognostic (1.16e-1)" "unprognostic (3.06e-2)" "unprognostic (8.75e-2)" "unprognostic (2.14e-2)" 8.1 7.7 14.3 5.0 19.0 2.3 10.6 20.4 20.1 15.8 8.8 21.7 10.2 7.2 14.4 13.6 10.7 14.5 8.6 8.9 13.8 12.0 11.5 6.0 9.0 4.0 13.7 13.3 12.4 24.9 21.9 13.2 8.0 13.9 11.4 10.0 9.6 17.0 12.1 10.3 7.0 6.8 11.0 20.7 5.8 8.7 20.0 12.6 5.0 12.4 5.2 5.9 10.5 7.9 4.1 7.4 10.9 3.4 3.6 6.0 3.1 19.1 9.0 7.0 10.3 4.3 5.2 8.9 9.6 8.1 9.0 11.9 7.6 13.6 0.0 7.1 10.0 5.5 10.9 7.7 9.7 10.2 4.8 9.2 5.6 3.4 4.5 16.9 4.1 5.4 10.5 16.1 9.1 6.0 5.5 12.6 4.9 3.5 7.4 8.5 9.7 2.3 6.3 7.6 10.3 9.1 0.0 6.7 6.7 13.2 7.1 13.7 12.2 7.2 15.0 7.0 7.9 20.1 3.6 10.0 8.4 6.0 6.7 4.9 5.7 7.6 0.0 0.0 4.5 6.2 10.9 3.4 2.9 3.3 1.9 6.0 4.1 3.5 3.3 7.4 2.4 4.2 6.0 0.4 3.6 1.7 5.8 2.4 3.1 14.3 19.0 20.4 20.1 13.8 12.0 13.7 13.3 13.9 12.6 11.9 7.5 3.2 4.2 2.9 9.4 10.3 5.1 9.4 9.1 0.0 7.9 7.1 5.0 10.0 2.4 4.4 3.2 0.0 7.6 3.8 4.6 4.8 1.1 4.7 5.6 9.5 5.8 10.4 5.9 1.8 5.8 1.8 3.3 9.0 8.7 6.8 9.0 7.0 11.3 4.8 8.7 0.0 3.9 31.0 8.7 3.8 2.4 0.5 6.9 3.0 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 45.5;pituitary gland: 30.8" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 7.5;Ciliated cells: 12.0;Club cells: 9.1;Early spermatids: 3.9;Late spermatids: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "NK-cell: 9.8" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.8" "Cell line enhanced" "Detected in some" "AN3-CA: 16.8;RH-30: 13.0;SH-SY5Y: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028917 Supported "Nucleoplasm,Nuclear bodies" NA NA "Nucleoplasm, Nuclear bodies" "HPA028917: AB_2672826" "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 1.0 1.1 2.8 0.6 16.8 0.5 0.6 0.2 6.8 4.0 0.6 1.9 0.0 0.7 0.6 2.2 1.0 2.5 0.8 4.6 2.8 2.2 0.6 0.5 1.0 0.6 2.9 2.8 0.8 0.6 45.5 30.8 0.6 4.2 12.4 0.7 15.3 1.2 4.6 3.2 0.6 0.7 3.9 0.4 0.7 0.9 1.3 5.1 4.4 0.9 2.9 0.6 3.5 5.7 0.8 1.9 1.8 2.3 9.8 2.3 0.2 0.1 0.0 3.8 16.8 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.3 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 1.2 0.0 0.9 0.0 13.0 5.5 0.0 0.0 1.3 31.6 0.0 0.0 1.0 3.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.2 1.8 0.3 0.6 0.9 0.9 1.9 0.8 0.7 1.9 0.7 0.8 1.3 1.4 1.6 9.8 2.3 1.9 2.3 0.2 2.8 16.8 0.2 2.8 2.8 2.2 2.9 2.8 4.2 5.1 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 12.0 9.1 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.7 1.0 0.1 0.5 0.0 0.0 0.0 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 47.4" "Cell type enhanced" "Detected in many" 11 "Basal glandular cells: 40.0;Club cells: 18.2;Cytotrophoblasts: 21.2;Urothelial cells: 36.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16 "memory B-cell: 2.4" "Lineage enriched" "Detected in single" 16 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "HBEC3-KT: 13.7;SCLC-21H: 20.9;SK-BR-3: 9.3;U-266/70: 38.9;U-266/84: 47.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA Cytosol "HPA027024: AB_1848334, HPA059291: AB_2683967" "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 10.5 2.0 6.5 2.6 7.4 0.8 13.4 2.4 6.5 47.4 6.4 3.8 21.0 1.0 15.7 10.7 25.9 28.2 2.2 4.3 7.0 4.1 5.2 1.8 2.3 1.3 6.3 4.9 5.2 2.4 11.5 4.7 5.9 9.1 18.5 3.2 15.4 28.6 27.3 2.1 4.2 1.1 2.3 7.2 1.1 8.2 4.9 5.1 14.3 21.4 3.6 14.0 5.5 17.3 2.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.9 0.7 0.1 13.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 20.9 0.0 0.0 9.3 0.0 1.1 1.8 0.1 0.0 0.0 1.7 0.1 3.1 38.9 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 7.4 2.4 6.5 7.0 4.1 6.3 4.9 9.1 5.1 0.0 0.0 0.0 40.0 0.6 0.2 0.5 0.0 6.7 18.2 0.0 5.9 21.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 1.8 4.7 9.2 1.1 2.4 5.8 0.0 1.2 0.6 0.0 0.0 0.0 0.2 3.3 4.6 0.2 0.0 0.7 1.7 0.7 4.4 0.3 0.0 1.4 0.2 0.7 0.3 9.0 0.0 1.5 36.7 EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088696 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052432, HPA062889" Uncertain Supported Nucleoplasm Yes No Nucleoplasm "HPA052432: AB_2681831, HPA062889: AB_2684895" "unprognostic (3.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (8.74e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.11e-4)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (4.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.13e-2)" "unprognostic (8.98e-2)" "prognostic favorable (3.15e-6)" "unprognostic (5.17e-2)" "unprognostic (2.79e-1)" "unprognostic (7.60e-2)" "unprognostic (6.11e-2)" 12.8 10.0 14.9 24.0 12.9 8.6 13.3 21.9 13.8 14.7 10.2 14.4 12.8 10.7 14.4 12.4 19.4 11.8 8.1 11.7 10.6 11.8 21.6 11.3 12.5 15.6 11.1 8.8 12.4 12.9 20.9 29.2 13.8 12.9 11.8 11.7 16.4 11.8 13.1 14.5 16.3 12.2 10.5 10.1 14.2 10.0 20.6 13.7 17.4 17.3 12.2 25.0 10.7 13.8 8.6 12.4 10.5 11.2 10.4 12.1 2.6 10.5 4.4 9.0 6.7 10.6 8.2 5.1 7.7 7.4 9.1 9.0 4.3 6.5 16.7 8.6 5.2 3.4 10.4 16.6 6.4 10.8 8.8 9.3 19.0 9.0 7.7 6.3 18.3 17.5 5.0 5.8 10.0 6.8 7.9 11.6 6.2 17.4 6.5 8.1 4.6 11.7 12.3 18.9 8.4 5.9 8.9 16.6 10.6 10.7 5.9 10.4 5.7 8.3 5.2 7.4 7.6 4.3 4.9 11.1 11.0 5.9 10.1 6.3 9.7 9.7 15.5 7.9 17.9 4.8 7.5 11.2 10.5 12.1 10.4 10.8 8.6 9.5 8.7 12.4 7.6 8.3 9.4 9.7 10.4 8.3 7.7 8.2 2.6 14.9 12.9 21.9 13.8 10.6 11.8 11.1 8.8 12.9 13.7 8.9 9.6 18.4 9.6 15.9 17.4 7.5 2.5 1.4 5.7 24.4 15.7 11.8 13.3 9.9 72.6 10.8 8.6 0.0 7.9 11.4 10.4 8.5 11.5 6.8 8.8 17.5 19.7 15.4 12.3 29.7 9.5 14.3 11.8 10.0 9.2 9.1 11.2 10.2 5.6 11.6 18.9 12.9 8.5 40.6 26.0 19.9 9.2 25.4 8.9 9.9 EYA4 "CMD1J, DFNA10" ENSG00000112319 "EYA transcriptional coactivator and phosphatase 4" O95677 6 133240598-133532120 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Cardiomyopathy, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 65.6" "Cell type enhanced" "Detected in some" 20 "Alveolar cells type 1: 11.9;Cardiomyocytes: 13.7;Collecting duct cells: 43.6;monocytes: 12.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 12.7;GAMG: 13.2;HeLa: 35.6;RH-30: 12.1;U-87 MG: 12.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004805, HPA038771, HPA038772" Enhanced Approved Nucleoplasm No NA Nucleoplasm "HPA004805: AB_10669750, HPA038771: AB_10671865, HPA038772: AB_10673119" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.27e-1)" "unprognostic (2.04e-9)" "unprognostic (1.64e-1)" "unprognostic (3.08e-2)" "unprognostic (3.44e-2)" "unprognostic (7.21e-2)" "unprognostic (9.07e-2)" "unprognostic (2.04e-2)" "unprognostic (2.80e-1)" "unprognostic (2.29e-1)" "unprognostic (8.27e-4)" "unprognostic (1.82e-3)" "unprognostic (6.67e-2)" "unprognostic (9.55e-2)" "unprognostic (2.51e-2)" 1.6 3.0 1.2 0.2 1.3 0.1 2.4 0.4 1.2 9.7 0.6 2.5 11.1 0.4 2.6 1.9 0.7 8.3 0.7 6.2 1.5 1.2 6.1 0.4 2.0 0.2 2.1 0.8 1.6 0.4 0.2 7.2 0.2 3.5 6.6 0.4 2.7 0.8 13.9 65.6 0.4 0.5 1.9 3.5 0.6 0.7 7.4 1.4 1.8 2.5 5.5 0.7 2.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 1.2 0.0 0.0 0.0 0.0 0.0 10.2 0.2 1.5 0.0 0.0 0.0 10.0 0.0 13.2 0.0 7.7 3.3 0.0 0.0 10.0 1.3 35.6 0.0 0.3 0.0 3.5 2.6 0.0 7.3 2.3 1.7 0.0 0.0 0.0 5.4 4.1 0.0 0.0 0.0 0.0 0.1 0.7 0.1 12.1 0.0 0.0 1.9 1.9 2.0 0.1 0.0 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 3.7 1.6 0.0 12.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.4 1.2 1.5 1.2 2.1 0.8 3.5 1.4 11.9 2.6 0.0 0.1 0.1 0.0 13.7 0.0 0.0 3.4 43.6 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 1.7 0.6 1.3 2.0 0.6 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.6 6.6 0.0 0.0 0.0 0.0 0.1 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122814-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 116.7" "Cell type enhanced" "Detected in many" 12 "Hepatocytes: 174.9;Leydig cells: 199.9;Peritubular cells: 222.0" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BJ: 8.5;BJ hTERT+: 6.8;CACO-2: 7.2;fHDF/TERT166: 7.6;Hep G2: 33.5;HHSteC: 7.0;SH-SY5Y: 16.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 16000000000 "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 8.1 3.7 0.3 2.9 0.7 0.0 5.4 0.4 0.8 20.3 5.9 0.6 7.6 4.5 12.6 21.4 4.5 9.9 10.0 18.4 0.5 0.5 2.3 116.7 4.9 1.6 0.5 0.7 18.2 3.0 0.0 1.7 3.6 1.0 18.1 0.7 6.9 2.0 6.1 2.6 7.8 7.6 11.7 0.6 1.3 3.2 9.5 0.6 0.6 3.1 5.6 1.8 7.8 10.3 0.0 0.0 0.0 0.0 0.9 1.0 0.3 0.0 0.0 1.5 0.2 4.9 5.0 0.0 8.5 6.8 0.5 0.2 7.2 0.0 0.0 0.3 7.6 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 33.5 7.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.1 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.6 16.6 0.0 0.3 0.0 0.3 0.3 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.3 0.3 0.7 0.4 0.8 0.5 0.5 0.5 0.7 1.0 0.6 0.0 0.0 0.0 0.0 14.0 1.0 4.8 7.6 0.0 0.0 1.8 0.0 0.6 0.0 0.0 2.6 2.1 0.3 0.0 0.0 0.6 66.0 0.1 1.1 174.9 1.2 6.4 17.1 9.8 4.5 5.6 199.9 0.3 18.6 1.0 1.4 3.8 0.5 2.9 222.0 5.6 1.1 51.8 54.2 2.1 1.1 13.4 0.9 2.5 0.9 0.2 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186265945-186288806 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 88.9" "Cell type enhanced" "Detected in some" 27 "Alveolar cells type 2: 19.3;Distal tubular cells: 10.0;Hepatocytes: 59.9" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 14.0" "Not detected" "Not detected" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 2.7 0.1 0.1 5.5 0.2 0.3 0.1 0.1 4.8 0.1 0.1 0.1 10.2 88.9 2.8 0.1 0.1 0.1 0.1 19.0 0.0 0.2 0.1 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.1 6.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.0 19.3 0.0 0.0 0.0 0.0 0.3 2.5 0.0 4.5 1.8 0.0 0.0 10.0 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402140-177409576 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "liver: 180.1" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 391.6" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 2.5;eosinophil: 6.9" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 2.5" "Cell line enhanced" "Detected in some" "HDLM-2: 8.7;MCF7: 11.1;PC-3: 8.2;SH-SY5Y: 5.6;U-937: 5.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA003825 Approved "Secreted to blood" NA NA 1040000 6600000000 "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favorable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.2 180.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 1.0 6.9 2.5 0.7 0.3 1.0 0.8 2.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 1.4 0.0 0.4 0.0 0.3 1.4 0.7 0.4 0.0 8.7 1.9 1.4 0.3 0.9 0.2 0.7 3.1 0.2 1.3 0.1 0.4 0.1 0.2 2.1 0.4 3.3 0.0 11.1 0.1 2.6 0.0 2.6 8.2 0.6 0.2 1.9 1.1 0.0 2.6 5.6 0.3 1.0 0.7 0.0 0.4 0.0 0.0 0.2 1.1 0.0 0.3 0.5 0.0 0.1 0.1 5.8 0.6 0.0 2.5 6.9 0.3 0.1 0.2 0.5 0.3 0.2 0.1 0.2 0.0 0.1 0.9 0.7 0.9 1.0 0.0 1.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 8.5 7.4 29.5 0.4 0.8 17.8 0.0 0.0 1.8 3.9 0.0 0.0 6.1 19.4 0.7 34.8 0.0 3.5 0.2 0.9 2.0 0.0 391.6 0.5 0.0 9.9 17.8 13.2 32.7 0.6 1.8 8.5 1.0 5.5 0.2 9.4 20.1 0.0 9.1 0.5 0.0 0.7 13.0 12.8 47.4 0.1 0.7 30.8 5.8 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719180-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 593 "liver: 324.8" "Cell type enriched" "Detected in some" 37 "Hepatocytes: 904.6" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "Hep G2: 78.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 43000000000 "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 324.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.6 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 904.6 0.0 0.0 0.0 24.5 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "liver: 68.0" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 131.2" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "gdT-cell: 1.7;MAIT T-cell: 1.2;memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 17 "T-cells: 1.7" "Group enriched" "Detected in some" 9 "CACO-2: 16.6;Hep G2: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1500000000 Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 68.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.6 0.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.2 0.0 0.5 0.0 0.0 131.2 0.1 0.0 0.0 3.7 3.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.1 0.1 0.9 0.1 0.1 0.5 0.0 0.0 F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530758-139563458 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2334 "liver: 233.6" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 475.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.8;RH-30: 2.0;SiHa: 1.6;U-698: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 11000000000 "prognostic favorable (6.69e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 233.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.2 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 475.1 0.0 0.0 0.0 15.4 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394265-46413848 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Enterocytes: 68.0;Late spermatids: 88.3;Spermatocytes: 73.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 19.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 22.2;OE19: 10.7;RT4: 23.9;SK-BR-3: 12.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 6.1 7.7 11.2 2.5 22.0 7.9 7.9 20.4 21.9 6.9 15.0 40.7 10.1 18.0 3.1 8.2 4.9 10.6 4.6 2.9 14.7 11.7 12.0 18.3 6.7 2.1 19.1 19.3 2.7 18.2 15.1 10.6 3.5 17.6 33.3 12.8 7.4 12.8 8.6 7.1 10.1 17.8 2.3 23.6 2.0 14.3 30.9 18.8 5.6 24.9 3.5 3.5 5.7 4.2 0.1 6.0 19.1 4.7 0.3 0.4 0.9 2.8 0.7 0.4 0.5 0.7 0.5 22.2 0.6 0.3 0.3 0.5 4.1 6.6 0.2 2.3 0.4 0.2 9.4 0.4 1.3 0.1 1.2 3.1 0.0 0.1 1.9 0.5 0.8 1.6 0.4 6.4 0.2 0.8 0.2 0.0 0.5 0.1 0.5 0.0 5.9 0.4 1.2 1.8 10.7 0.2 0.5 0.2 0.1 5.2 23.9 2.8 2.1 3.2 12.4 0.1 0.6 8.5 8.2 0.0 0.0 0.3 0.6 0.4 1.2 0.5 0.3 0.1 7.6 0.2 0.0 4.7 19.1 0.3 1.2 0.1 0.0 0.3 0.1 5.7 0.1 0.4 0.4 0.2 0.3 0.6 6.0 0.1 0.9 11.2 22.0 20.4 21.9 14.7 11.7 19.1 19.3 17.6 18.8 20.8 10.4 4.2 27.1 4.6 12.6 2.2 25.5 4.0 10.3 21.0 41.2 14.4 0.0 12.8 35.5 1.8 68.0 0.0 5.6 6.3 2.4 27.0 0.0 29.2 2.6 1.6 14.9 0.6 3.2 88.3 6.9 2.9 5.0 0.0 33.1 6.3 5.0 40.4 4.2 19.5 11.4 0.0 2.7 73.1 7.7 5.3 10.4 0.0 48.5 12.3 FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489196 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 43.6;pituitary gland: 42.8" "Cell type enhanced" "Detected in many" 5 "Ciliated cells: 24.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "cerebellum: 18.0" "Cell type enhanced" "Detected in many" "T-reg: 13.6" "Lineage enriched" "Detected in many" 8 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.7;HDLM-2: 9.6;RPMI-8226: 19.4;U-266/70: 16.3;U-266/84: 8.3" NA NA "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favorable (2.66e-4)" "prognostic favorable (6.83e-5)" 1.0 1.4 1.0 6.8 1.5 0.0 6.7 18.0 1.0 3.5 3.9 0.2 3.8 2.6 1.4 4.7 5.5 5.8 2.4 0.6 1.2 2.3 9.7 20.1 3.5 5.7 1.1 0.5 1.9 43.6 12.7 42.8 1.4 1.8 9.3 3.6 3.8 9.1 5.3 0.3 10.0 6.4 0.6 1.1 2.3 4.1 0.6 0.3 8.5 15.3 2.7 11.0 3.0 3.6 1.8 1.0 0.3 0.0 0.7 13.6 1.5 2.5 0.2 0.0 0.1 0.1 0.1 2.4 0.0 0.0 0.0 0.0 1.8 10.7 0.1 3.1 0.0 0.0 0.4 0.8 1.9 0.0 9.6 5.2 0.3 2.5 0.7 0.0 1.1 0.0 0.0 3.2 0.0 0.0 0.1 0.0 1.0 1.2 4.8 0.0 1.0 0.5 0.0 1.8 2.2 0.0 0.0 1.8 19.4 6.3 3.4 1.8 0.1 0.1 3.0 0.0 4.6 3.0 0.0 0.0 0.0 0.2 0.0 0.1 16.3 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 4.7 1.8 7.7 3.2 0.0 0.6 7.5 0.9 0.3 0.7 0.0 1.0 13.6 1.5 1.0 1.5 18.0 1.0 1.2 2.3 1.1 0.5 1.8 0.3 3.0 5.6 0.0 11.2 2.4 3.1 0.3 2.5 24.1 6.8 5.2 17.7 4.4 8.3 8.3 0.0 0.0 3.9 0.0 12.2 2.1 0.5 10.4 0.0 9.0 0.6 1.6 12.7 0.6 0.0 0.0 0.6 0.0 3.3 1.0 5.6 1.2 11.6 3.4 0.4 4.5 12.2 0.0 0.1 0.0 0.0 5.8 4.7 2.5 4.7 9.0 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 250.1;Hofbauer cells: 63.7;Proximal tubular cells: 236.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 76.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 230000000 Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 32.1 17.8 4.6 6.1 3.6 4.7 22.8 2.3 3.3 4.7 8.6 3.1 8.3 4.1 5.1 14.8 4.4 6.8 7.1 6.8 4.1 2.8 18.9 109.4 7.9 6.2 4.0 2.1 7.2 6.5 4.8 4.4 2.3 3.5 4.9 3.4 2.4 5.3 5.4 7.7 2.4 7.6 4.4 5.9 6.0 3.3 9.7 3.0 2.3 4.2 4.9 3.9 4.1 6.1 0.1 16.0 16.9 11.7 3.6 5.8 6.1 4.5 7.6 3.1 3.9 14.7 15.1 7.8 5.8 13.3 6.2 5.3 4.6 8.4 0.0 9.6 12.2 8.6 6.7 11.2 13.9 6.0 2.9 6.3 38.8 4.5 23.8 76.6 18.3 21.5 26.1 8.6 5.3 9.6 20.3 8.6 8.9 16.2 8.3 11.5 6.9 5.0 9.1 2.2 3.5 8.7 2.8 4.5 29.1 17.8 5.5 0.1 1.9 6.5 18.0 18.2 5.3 13.7 12.5 29.9 11.3 7.1 6.0 9.8 7.6 15.5 3.1 23.5 42.9 6.3 16.9 11.7 1.9 5.8 4.9 1.5 0.1 1.6 3.9 16.0 0.0 2.0 1.8 0.7 3.6 4.8 1.2 1.5 6.1 4.6 3.6 2.3 3.3 4.1 2.8 4.0 2.1 3.5 3.0 3.0 14.4 5.2 13.1 6.1 0.4 12.0 10.2 5.3 4.5 31.4 0.0 32.5 44.7 8.5 6.3 2.5 15.8 23.3 3.1 9.0 17.2 8.6 42.5 250.1 63.7 0.0 4.1 11.1 20.0 10.6 9.2 23.1 18.6 3.6 11.8 3.5 4.6 14.4 7.4 236.8 0.3 0.0 8.1 1.5 2.1 5.0 18.4 8.7 22.4 12.8 FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Proximal tubular cells: 175.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favorable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" 10.4 17.0 10.4 6.7 9.9 6.5 9.2 8.6 12.7 6.8 21.7 9.3 8.2 26.7 9.8 10.9 14.8 5.8 10.2 15.8 10.9 11.4 46.8 43.6 5.6 5.2 10.1 9.4 7.9 17.4 9.0 11.1 10.4 9.9 8.1 11.1 8.5 9.1 9.8 20.2 12.4 24.8 6.9 8.8 6.3 14.9 6.9 9.5 4.7 12.5 19.0 5.7 9.9 7.9 18.5 23.1 8.6 27.5 19.6 16.0 13.7 8.4 19.1 9.1 16.1 12.1 8.8 5.7 13.9 6.9 9.3 10.2 12.2 8.8 5.4 11.7 8.6 14.4 17.4 7.1 11.2 8.4 8.2 16.9 4.8 16.5 28.1 11.8 8.3 9.4 11.6 14.7 8.5 5.7 7.9 12.1 6.6 5.0 5.7 11.6 38.7 4.5 12.6 5.4 7.8 14.3 10.4 12.4 15.2 33.4 10.6 17.8 14.8 18.2 14.7 21.8 6.4 21.5 5.7 17.6 15.3 10.9 9.0 7.5 8.2 17.2 6.4 9.7 6.1 6.5 6.5 23.5 8.6 14.4 27.5 13.0 18.5 14.5 15.7 23.1 16.9 16.0 14.9 2.0 19.6 19.1 17.9 14.7 13.7 10.4 9.9 8.6 12.7 10.9 11.4 10.1 9.4 9.9 9.5 23.8 16.0 12.3 12.4 12.5 20.0 37.0 22.9 17.4 17.0 40.1 25.5 18.6 43.1 43.5 88.6 14.7 72.1 23.3 34.0 12.3 14.7 9.4 4.7 30.5 26.4 17.5 28.2 8.0 8.1 38.9 13.6 18.2 15.1 23.4 22.1 16.9 34.9 30.9 14.5 175.3 22.4 12.9 14.1 7.0 8.3 21.0 12.8 10.7 41.2 8.1 FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30903852-30943108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" NA NA Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA048198: AB_2680311" "unprognostic (7.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.67e-2)" "prognostic favorable (1.42e-6)" "unprognostic (3.73e-1)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (1.29e-1)" 5.9 8.9 11.6 6.9 17.4 6.3 12.7 19.6 18.4 15.0 11.4 17.7 11.9 4.6 11.6 22.9 6.5 8.5 8.5 13.0 12.6 11.0 14.7 14.4 6.9 5.5 18.5 11.8 12.5 18.2 7.2 17.0 10.6 15.4 16.4 9.7 8.6 17.3 8.3 16.8 9.3 6.7 11.5 13.0 7.3 8.5 9.4 15.0 5.1 14.3 6.3 5.8 9.0 9.1 4.0 3.6 0.6 1.7 4.5 5.4 1.6 6.3 10.9 3.6 2.0 12.9 11.5 2.4 4.5 1.9 4.8 5.0 7.5 3.3 1.4 8.0 4.8 10.0 12.9 6.1 9.4 4.7 5.1 2.9 1.1 11.2 1.3 5.6 0.9 6.1 3.4 7.0 2.9 7.6 10.4 2.3 6.6 5.4 10.0 7.8 1.4 9.9 4.4 2.8 10.2 2.5 8.4 11.8 2.7 7.0 5.0 8.3 5.8 9.9 6.8 3.5 13.6 6.1 7.6 8.2 15.0 3.6 4.1 5.7 13.8 9.6 1.7 6.5 4.8 1.3 0.1 0.8 0.6 3.7 1.3 4.7 2.8 3.5 1.7 2.7 4.0 5.4 2.8 0.3 4.5 1.7 3.6 3.2 1.6 11.6 17.4 19.6 18.4 12.6 11.0 18.5 11.8 15.4 15.0 14.9 9.6 0.8 4.9 3.7 20.0 15.7 0.0 16.0 13.6 8.7 19.6 5.5 8.3 3.3 8.7 6.7 3.8 0.0 2.5 1.8 3.5 4.6 8.1 11.0 3.2 25.4 7.5 8.0 4.1 5.8 9.8 4.1 5.0 2.8 9.7 14.7 3.3 2.9 6.3 5.1 24.3 6.5 4.2 19.5 12.9 2.0 3.4 6.9 8.3 3.1 FANCM "FAAP250, KIAA1596" ENSG00000187790 "Fanconi anemia complementation group M" Q8IYD8 14 45135940-45200890 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 55.9;Late spermatids: 151.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055144 Supported Nucleoplasm NA NA Nucleoplasm "HPA055144: AB_2682715" "unprognostic (8.40e-2)" "unprognostic (6.70e-2)" "unprognostic (3.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.15e-1)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.57e-2)" "unprognostic (8.52e-2)" "unprognostic (1.14e-1)" "unprognostic (1.23e-2)" "unprognostic (7.55e-2)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (8.94e-2)" "unprognostic (1.13e-2)" 4.7 3.9 3.9 4.4 8.4 9.8 5.7 8.2 7.9 5.7 3.5 4.9 4.9 2.6 6.7 4.8 4.5 4.2 3.7 3.8 3.4 3.3 4.1 3.1 3.3 6.6 3.2 3.6 6.2 3.3 4.5 4.5 4.4 9.3 3.5 3.8 4.8 4.1 4.8 4.2 5.2 3.5 3.8 3.4 8.9 3.2 15.4 4.2 15.2 3.3 2.9 6.4 3.8 4.3 6.7 3.2 7.6 3.6 2.0 4.1 1.1 7.8 6.8 8.1 7.5 6.4 4.0 6.5 10.3 4.0 8.1 10.5 11.0 6.0 10.3 5.9 2.4 4.6 10.6 9.5 4.4 11.1 7.5 5.2 4.7 7.7 6.0 1.2 12.3 6.1 2.3 1.6 8.1 5.1 1.8 6.9 6.7 8.5 9.1 6.7 7.8 9.0 8.8 3.2 6.0 11.5 8.4 12.6 4.7 3.3 5.6 7.4 1.9 9.1 7.5 3.8 5.4 8.0 5.7 5.4 11.8 11.1 10.8 7.7 4.6 8.3 10.3 2.3 7.6 7.0 7.6 1.3 4.6 4.0 3.6 2.2 6.7 2.5 1.5 1.0 4.2 4.1 3.5 2.1 2.0 1.7 3.2 1.7 1.1 3.9 8.4 8.2 7.9 3.4 3.3 3.2 3.6 9.3 4.2 0.0 1.9 1.5 1.2 2.4 5.2 6.7 2.5 0.0 3.4 1.8 2.0 6.7 0.0 1.6 55.9 2.7 1.0 0.0 2.3 2.8 2.3 0.8 1.1 1.7 3.0 3.2 0.0 5.5 3.7 151.5 8.3 2.7 3.3 4.6 1.6 4.4 1.5 0.0 4.9 1.5 6.1 6.5 4.1 23.6 14.4 1.6 1.9 3.3 2.6 0.3 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.0" "Group enriched" "Detected in many" 6 "Fibroblasts: 25.9;Muller glia cells: 68.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 45.4;ASC TERT1: 48.2;BJ hTERT+: 38.0;hTERT-RPE1: 48.7;U-138 MG: 38.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA059739 Uncertain "Secreted to blood" NA NA 34000000 "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 19.8 0.7 2.6 3.2 1.2 0.0 7.5 0.6 3.7 17.6 4.5 0.4 4.0 0.1 30.0 13.7 4.1 5.1 14.9 5.2 3.1 0.9 2.0 0.9 4.7 0.8 2.6 1.2 4.1 2.3 0.5 1.0 17.0 1.9 4.1 1.5 2.4 5.3 3.9 8.1 2.9 1.4 17.9 2.2 0.9 1.7 9.8 3.4 0.0 3.5 9.0 0.8 12.4 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.4 48.2 0.0 18.5 38.0 3.9 5.9 0.0 0.0 0.0 0.1 7.0 0.0 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.2 0.0 4.6 0.0 0.0 15.5 0.2 6.4 1.2 48.7 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 1.9 0.0 0.0 0.0 19.0 38.7 0.7 9.4 0.0 0.0 0.0 0.0 8.7 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.2 0.6 3.7 3.1 0.9 2.6 1.2 1.9 3.4 0.0 0.0 0.0 0.1 3.9 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 3.9 2.9 0.0 0.0 0.2 1.6 25.9 0.1 0.0 0.0 0.8 1.6 4.7 2.5 0.0 2.3 7.8 0.3 3.3 0.0 0.0 68.0 1.6 0.0 0.0 0.6 1.5 0.0 1.4 0.2 0.0 3.8 1.5 0.0 0.0 0.0 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078333-82098332 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 147.6" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 103.0;Hepatocytes: 169.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 155.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 1600000 "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 147.6 7.8 8.2 14.2 11.5 11.1 57.5 19.1 23.0 6.6 27.7 17.0 14.1 8.2 4.7 14.2 17.1 4.3 19.4 6.3 7.9 6.7 3.7 30.8 26.8 9.8 7.3 11.5 6.4 10.4 6.7 15.3 8.4 21.7 28.8 3.4 7.6 16.9 10.8 7.5 17.2 6.5 4.6 8.4 5.1 11.9 6.6 8.8 1.9 5.1 10.7 5.4 8.0 6.6 0.5 1.4 0.0 0.8 0.2 1.9 0.8 23.6 24.8 11.5 7.9 18.7 12.7 24.7 4.7 6.1 5.0 9.2 25.9 16.1 7.9 3.9 3.6 14.0 19.7 11.1 21.7 0.9 3.7 48.3 16.3 18.5 34.6 5.3 8.8 2.5 12.1 5.7 12.7 3.0 1.7 5.6 7.4 24.6 7.0 1.7 40.9 9.5 14.0 22.4 3.7 14.4 8.5 6.5 15.6 5.6 30.3 28.7 16.0 6.9 155.8 12.6 4.4 27.8 16.8 9.7 7.3 15.1 6.0 11.3 9.5 2.1 8.1 4.4 9.6 10.8 0.0 0.8 0.0 1.2 0.5 0.7 0.5 1.9 1.4 1.4 0.2 0.7 0.6 0.0 0.2 0.4 1.1 0.6 0.8 8.2 11.5 19.1 23.0 7.9 6.7 7.3 11.5 21.7 8.8 23.8 103.0 0.8 10.3 6.9 24.9 4.8 25.5 6.7 10.3 10.4 5.9 28.9 3.3 18.9 1.2 4.5 20.8 23.3 24.9 65.8 10.4 65.5 12.7 169.2 11.7 28.6 17.4 11.1 6.9 1.3 15.3 5.0 16.9 8.2 18.9 12.3 16.1 17.5 10.6 5.5 9.5 0.0 9.6 1.9 13.9 12.0 24.7 10.7 18.3 17.5 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 248.1;lung: 87.8" "Cell type enhanced" "Detected in many" 13 "Hepatocytes: 322.6;Proximal tubular cells: 631.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "eosinophil: 73.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 20.5;MCF7: 64.2;RT4: 42.1;SK-BR-3: 12.3;U-698: 30.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 23000000 Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" 19.3 5.8 0.6 2.3 0.9 1.1 7.0 0.4 0.8 2.2 48.8 0.7 17.6 40.7 0.6 2.5 0.7 0.9 9.7 1.3 0.8 0.5 34.6 248.1 87.8 8.9 0.9 0.7 1.0 8.1 17.1 1.9 1.0 1.0 6.4 3.0 1.5 9.1 17.7 0.5 1.7 60.4 3.1 1.2 2.8 10.4 1.0 0.8 0.5 4.3 1.0 1.1 22.4 9.6 0.6 17.1 73.5 30.7 2.8 3.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 64.2 0.0 1.1 0.2 10.4 2.3 0.0 0.2 0.4 0.0 42.1 0.2 1.2 0.1 12.3 0.0 0.2 7.3 1.8 0.0 0.0 0.2 0.2 0.0 0.0 0.2 30.5 0.0 0.3 0.0 10.6 13.0 73.5 1.5 30.7 2.3 0.6 0.9 0.9 17.1 0.6 3.3 1.6 2.3 2.8 16.3 6.1 0.4 5.2 0.6 0.9 0.4 0.8 0.8 0.5 0.9 0.7 1.0 0.8 71.5 142.5 10.2 6.5 0.7 0.0 0.6 107.0 13.4 68.2 59.3 0.0 9.7 94.5 14.4 0.0 1.8 32.6 23.3 56.4 1.6 1.7 17.4 45.2 322.6 187.5 0.0 30.7 11.1 49.8 0.8 1.4 103.2 11.8 0.0 49.9 2.1 23.8 68.4 3.9 631.0 0.0 6.5 1.2 0.6 0.1 0.9 8.5 13.1 59.5 51.2 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 33.7;skeletal muscle: 134.7;tongue: 45.6" "Cell type enhanced" "Detected in some" 29 "Exocrine glandular cells: 1.2;Spermatogonia: 3.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 36 "pons and medulla: 33.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.1;CACO-2: 3.6;HMC-1: 4.0;MCF7: 5.3;OE19: 5.0;PC-3: 3.7;SiHa: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA012513: AB_1848446, HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 2.0 0.4 0.1 0.0 0.1 0.0 0.2 0.1 0.9 0.1 0.1 3.8 4.4 1.0 0.1 1.0 1.6 0.1 0.0 0.1 0.7 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.1 1.2 4.1 0.1 0.0 33.7 0.2 0.0 5.0 1.4 1.8 134.7 0.1 0.1 0.1 0.2 0.1 9.0 0.4 0.0 0.0 0.2 45.6 2.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.3 0.0 2.5 0.0 0.0 7.1 0.0 0.0 0.1 0.0 3.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 1.9 2.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 5.0 3.7 0.0 0.0 0.1 0.0 2.4 0.6 0.1 4.9 1.1 0.0 0.2 0.4 0.1 0.0 0.0 2.3 2.2 0.0 0.0 0.1 1.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.7 0.1 0.1 0.0 33.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.1 0.0 0.0 0.0 FBXO18 "FBH1, Fbx18, FLJ14590" ENSG00000134452 "F-box protein, helicase, 18" Q8NFZ0 10 5890203-5937594 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002844 Supported NA NA "HPA002844: AB_1078829" "unprognostic (3.14e-2)" "unprognostic (1.55e-1)" "unprognostic (6.35e-3)" "unprognostic (4.42e-2)" "unprognostic (3.37e-2)" "unprognostic (8.98e-3)" "prognostic unfavorable (7.73e-7)" "unprognostic (1.89e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (1.56e-2)" "unprognostic (2.23e-1)" "unprognostic (6.91e-3)" "unprognostic (3.69e-1)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (9.54e-2)" 21.3 30.6 21.0 22.4 28.2 18.8 32.7 23.0 21.8 23.5 21.9 18.1 26.3 21.7 30.6 21.2 23.8 28.7 22.8 35.1 21.0 13.4 20.4 23.2 22.5 24.2 19.4 18.0 27.5 26.2 23.3 24.5 23.6 22.5 23.9 22.1 23.1 21.0 24.8 23.6 26.2 23.4 27.5 13.5 29.7 22.4 27.1 20.1 36.8 22.8 14.9 23.3 23.8 33.8 6.1 6.1 4.8 3.2 7.2 9.2 2.5 14.5 15.9 15.0 16.3 34.5 22.9 13.5 16.8 11.6 16.8 18.8 18.7 13.4 13.6 11.1 24.5 8.0 21.8 20.1 17.9 15.2 14.7 14.9 13.1 12.6 15.9 23.7 6.5 12.7 28.6 17.5 21.2 9.4 21.3 28.3 18.7 22.9 14.5 17.7 22.0 15.5 9.5 6.8 25.3 9.0 17.2 7.1 22.7 16.3 11.9 8.5 12.8 17.3 15.8 23.4 18.0 16.0 13.1 17.6 10.7 12.1 28.2 12.9 14.8 11.7 7.6 14.5 9.6 7.5 0.0 3.2 4.8 3.2 2.5 2.1 4.9 3.3 4.1 3.0 6.1 4.0 2.9 2.1 7.2 1.9 6.1 9.2 2.5 21.0 28.2 23.0 21.8 21.0 13.4 19.4 18.0 22.5 20.1 20.8 15.4 5.2 13.7 19.6 18.1 0.0 17.8 9.4 4.5 0.0 33.4 16.4 0.0 0.0 12.0 17.5 18.0 0.0 0.0 16.7 19.1 17.5 15.1 18.4 13.9 30.2 16.7 39.9 18.1 5.2 24.7 12.3 21.9 0.0 15.6 19.9 0.0 14.4 29.0 0.0 19.5 51.8 15.1 23.1 31.2 22.1 26.8 8.7 20.3 13.7 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad" P49789 3 59749310-61251459 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 138.8;Proximal tubular cells: 112.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "naive CD4 T-cell: 38.3" "Lineage enriched" "Detected in all" 14 "T-cells: 38.3" "Cell line enhanced" "Detected in many" "RPMI-8226: 12.1;U-266/70: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 6.4 24.0 13.7 8.0 17.5 9.0 12.1 4.7 13.3 7.9 8.0 21.0 12.4 8.2 6.2 9.5 5.1 9.2 13.0 14.9 15.3 13.8 30.9 10.7 5.2 9.3 19.5 9.3 8.9 11.8 16.3 15.2 4.1 14.4 5.8 7.8 14.0 11.4 9.9 11.6 7.0 7.6 9.1 17.1 6.0 8.1 10.5 18.2 3.7 15.6 5.7 6.9 7.3 6.1 1.6 2.4 1.8 1.8 2.6 38.3 4.7 0.0 0.0 1.0 0.0 0.6 0.0 1.7 0.1 0.1 0.0 0.0 1.8 3.1 2.6 0.5 0.1 1.9 0.0 10.1 2.1 0.0 1.4 3.5 2.2 1.3 4.2 2.7 5.7 0.1 6.9 4.2 0.1 5.1 0.2 0.0 2.8 1.7 8.4 0.1 2.5 10.2 4.6 0.8 8.7 0.6 7.6 0.0 12.1 11.3 1.4 2.1 2.9 1.0 7.0 6.6 4.1 0.4 0.1 0.0 1.2 0.4 0.1 1.6 24.7 7.5 0.0 2.7 0.0 1.5 1.8 1.8 0.2 0.9 1.2 0.5 1.6 6.9 0.7 2.2 1.4 38.3 6.7 0.3 2.6 0.4 2.4 7.4 4.7 13.7 17.5 4.7 13.3 15.3 13.8 19.5 9.3 14.4 18.2 6.0 8.8 14.1 16.1 6.8 12.4 9.2 33.1 2.7 3.4 26.2 55.0 33.8 66.3 17.3 41.1 6.2 12.3 0.0 4.1 6.5 4.3 10.2 5.7 20.8 17.6 28.6 7.5 11.6 6.7 138.8 17.8 9.6 11.8 6.4 11.4 17.8 11.6 14.0 9.2 112.3 19.5 0.0 3.1 18.1 6.4 9.8 27.3 7.5 17.2 19.0 FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49146635-49208670 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.7;intestine: 111.2;prostate: 33.8" "Cell type enhanced" "Detected in some" 16 "Glandular cells: 41.1;Hepatocytes: 24.1;Muller glia cells: 17.3;Proximal tubular cells: 22.6" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HAP1: 5.4;RPMI-8226: 3.8;SK-BR-3: 4.5;TIME: 2.9;U-2 OS: 2.7;WM-115: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" 1.2 1.0 10.4 0.9 16.4 0.8 2.5 1.4 12.7 1.4 67.6 37.7 0.0 111.2 1.3 0.8 1.2 2.1 5.0 0.7 16.9 8.7 6.1 15.7 1.1 0.9 19.0 9.1 1.0 0.7 0.7 0.4 0.7 17.7 33.8 0.8 0.6 20.7 0.8 0.6 1.2 61.1 1.0 33.0 1.5 1.0 0.9 16.2 0.0 1.0 0.0 0.8 1.2 0.5 0.9 0.1 0.3 0.8 1.4 1.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.7 0.0 0.2 0.2 5.4 0.5 0.0 1.3 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.1 1.0 0.2 0.0 0.4 0.3 3.8 0.0 0.0 0.4 1.7 0.0 4.5 1.0 0.6 1.0 0.0 2.9 0.2 2.7 0.4 0.3 0.1 0.5 0.1 0.0 0.9 5.4 0.1 0.8 0.3 0.9 0.6 0.2 0.6 1.2 0.5 0.0 0.9 0.7 0.3 0.2 1.4 0.5 0.1 0.4 0.0 10.4 16.4 1.4 12.7 16.9 8.7 19.0 9.1 17.7 16.2 0.0 1.1 0.0 0.8 0.2 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 6.6 0.0 3.5 0.3 0.0 0.0 0.0 0.0 0.4 41.1 0.0 24.1 0.1 0.0 0.0 3.1 0.0 1.0 1.4 0.0 3.3 0.0 0.0 17.3 0.0 0.0 0.4 22.6 0.2 0.0 0.3 0.2 1.6 0.6 0.0 0.0 0.0 0.5 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868294 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 182.1;Paneth cells: 168.7;Syncytiotrophoblasts: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced "Intracellular and membrane" NA NA 65000000 "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 15.8 18.0 4.6 24.1 7.1 0.9 8.9 4.2 8.1 13.1 30.2 6.9 28.4 20.4 9.9 35.7 8.7 12.7 22.6 15.0 4.7 6.4 28.9 39.3 20.7 66.7 4.8 4.7 19.4 15.5 12.2 10.9 31.9 8.0 15.2 33.5 13.8 22.6 18.5 6.9 6.6 42.3 7.4 7.1 32.3 14.8 15.6 2.9 11.6 27.3 8.0 25.1 23.6 7.8 8.3 15.2 16.8 34.8 14.4 9.9 19.0 5.3 3.6 0.7 11.0 1.5 0.1 3.8 5.7 11.9 6.0 11.2 4.9 56.8 8.0 14.4 7.2 6.6 3.2 5.3 12.1 7.9 5.6 8.8 6.6 3.3 10.9 5.1 0.6 22.0 5.5 6.9 2.2 2.9 19.5 2.4 4.6 3.0 0.1 7.1 5.8 1.6 5.9 1.8 16.2 5.8 9.0 0.0 8.7 22.2 13.8 3.8 3.7 16.4 6.4 8.6 6.6 4.7 2.6 0.6 2.0 3.2 13.6 1.9 10.0 10.1 2.9 5.1 19.9 3.2 13.7 34.8 16.8 9.9 34.5 8.5 8.3 7.2 8.4 15.2 4.7 7.0 8.2 4.3 14.4 28.7 8.8 7.0 19.0 4.6 7.1 4.2 8.1 4.7 6.4 4.8 4.7 8.0 2.9 23.8 22.9 10.4 24.6 3.2 3.4 5.7 40.8 24.1 30.7 80.3 0.0 146.1 13.3 48.0 39.6 10.1 182.1 0.0 44.7 19.3 14.8 27.9 8.1 29.4 139.0 0.0 10.4 23.9 89.5 15.5 21.6 35.0 8.5 9.0 39.6 13.3 29.7 168.7 18.4 28.4 4.8 6.5 5.6 78.8 10.6 2.5 167.7 13.8 63.2 33.2 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494811-143511690 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 53000000 "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 22.6 32.6 10.3 14.2 16.2 11.6 24.1 6.2 11.4 18.5 21.2 17.6 23.1 22.0 17.9 24.8 11.9 17.2 25.0 25.6 11.6 11.8 34.1 45.7 21.7 30.0 20.4 8.7 21.9 32.6 52.3 14.4 40.7 16.9 12.0 28.4 21.4 18.9 24.5 6.7 9.3 29.5 14.6 18.5 20.3 20.4 11.0 16.1 3.6 17.9 8.7 10.3 16.7 15.0 4.1 22.9 9.3 29.3 9.7 6.7 14.9 23.3 13.7 11.9 21.7 17.8 35.0 22.7 22.1 23.7 27.3 46.5 26.1 23.5 0.0 16.6 29.6 8.6 0.1 6.0 2.9 38.0 20.9 23.0 7.8 25.6 39.3 25.7 0.0 4.0 18.6 17.5 24.4 10.6 23.3 27.7 0.0 27.8 12.3 30.7 27.6 0.0 18.2 15.5 10.7 18.9 0.0 25.1 17.3 32.4 14.6 9.0 5.9 24.3 16.3 19.8 9.6 8.0 19.3 16.2 16.3 13.8 40.6 42.5 4.5 4.9 0.1 18.8 14.4 5.6 9.3 29.3 8.7 4.9 28.8 5.6 4.1 3.6 4.1 22.9 2.5 1.6 3.0 2.0 9.7 20.0 3.5 6.7 14.9 10.3 16.2 6.2 11.4 11.6 11.8 20.4 8.7 16.9 16.1 38.7 28.1 11.5 10.0 10.0 2.5 22.9 30.6 22.7 15.9 24.4 0.0 45.1 10.0 64.9 1.4 23.4 39.4 23.3 109.4 92.6 60.3 14.4 36.9 31.6 98.2 1.6 9.2 25.8 46.4 0.9 61.9 43.0 40.5 41.5 35.4 11.3 60.3 28.1 42.8 36.9 0.8 6.5 23.7 3.7 3.6 6.9 38.8 12.9 49.1 15.7 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868592-90883458 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "liver: 118.4;placenta: 158.9;salivary gland: 337.9" "Cell type enhanced" "Detected in many" 5 "Exocrine glandular cells: 102.2;Hepatocytes: 114.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA 41000 "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 8.3 3.3 3.0 7.5 3.6 16.6 5.9 5.0 4.4 4.1 6.6 2.8 3.5 5.7 4.9 10.8 4.7 4.4 3.9 6.9 3.1 1.8 6.4 118.4 9.5 3.1 2.8 2.7 4.2 22.5 3.8 7.2 158.9 3.5 9.3 2.2 3.0 337.9 4.7 8.7 9.0 5.9 3.1 3.0 8.2 6.0 5.3 2.9 4.8 8.9 5.5 4.1 4.4 4.3 1.5 3.3 10.3 3.3 3.1 1.9 2.0 14.4 8.8 2.0 8.9 14.5 9.4 22.7 18.2 13.9 7.5 5.3 12.9 15.8 0.5 46.8 13.2 13.5 26.0 4.0 9.4 1.6 41.6 10.3 25.3 15.8 16.8 7.7 3.5 41.7 10.6 10.6 8.5 3.9 18.3 24.0 4.2 19.3 2.5 5.0 9.9 1.3 11.4 6.3 12.2 2.6 2.2 7.7 3.3 11.7 11.0 4.0 2.7 15.4 8.4 12.8 9.9 3.0 9.2 35.4 8.5 18.2 13.0 26.6 4.5 25.6 1.2 16.2 11.4 17.2 7.5 3.3 10.3 1.9 1.1 1.4 1.5 1.2 1.2 2.1 1.0 0.6 0.8 7.4 3.1 0.7 3.3 0.9 2.0 3.0 3.6 5.0 4.4 3.1 1.8 2.8 2.7 3.5 2.9 3.0 30.9 6.7 7.5 17.2 11.9 15.0 10.2 1.4 5.7 21.0 23.6 16.5 0.0 44.3 0.4 25.5 23.8 23.3 102.2 11.4 12.3 26.5 15.1 114.9 22.3 7.9 36.4 23.4 26.1 0.2 10.3 24.1 15.1 7.2 27.3 11.7 83.4 21.8 10.3 5.6 25.2 25.8 12.5 2.3 3.4 20.1 70.5 11.7 16.1 13.9 G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812785 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol NA NA 150000 Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" 36.7 27.5 21.1 29.1 23.7 12.2 29.7 24.3 21.4 28.5 23.4 27.7 19.6 18.1 29.9 19.3 40.7 26.5 20.7 24.8 21.7 21.2 30.7 44.1 25.9 36.8 31.8 16.7 38.2 30.6 29.9 29.9 27.9 24.9 24.5 27.2 22.6 24.1 19.7 66.4 25.3 22.8 27.0 27.4 28.9 20.6 27.4 25.8 57.1 28.9 37.0 42.3 27.7 34.8 25.6 19.9 19.5 19.1 29.4 40.0 32.1 37.7 29.5 36.4 15.9 46.4 25.2 42.0 37.5 34.0 48.4 57.5 54.2 49.0 70.5 55.2 34.8 42.3 35.9 54.9 72.8 63.5 19.5 26.4 43.6 27.3 36.3 26.5 54.5 28.8 25.1 39.8 42.1 41.7 19.8 39.9 28.5 34.1 34.8 47.4 20.3 45.9 24.2 40.6 27.5 30.3 42.2 46.0 33.6 31.8 37.6 34.4 24.9 35.5 51.7 54.3 35.9 41.3 30.3 43.4 35.0 40.8 33.1 68.1 21.7 29.9 55.5 26.3 42.0 63.1 19.5 13.9 13.0 25.7 19.1 40.0 25.6 34.4 28.7 18.0 21.9 33.0 32.9 6.1 29.4 16.8 19.9 34.0 32.1 21.1 23.7 24.3 21.4 21.7 21.2 31.8 16.7 24.9 25.8 17.9 30.0 62.3 74.5 212.8 33.8 51.5 48.4 65.6 61.4 61.1 15.7 86.5 66.3 65.2 35.3 78.7 31.9 23.3 45.9 73.7 92.5 76.9 72.7 138.2 69.1 54.0 48.1 74.9 78.1 21.9 60.1 59.1 82.7 88.4 55.3 50.3 51.8 38.6 53.7 64.9 35.6 38.8 106.6 46.3 99.0 224.2 56.3 61.0 68.9 82.6 G6PC "G6PT, GSD1a" ENSG00000131482 "Glucose-6-phosphatase catalytic subunit" P35575 17 42900797-42913369 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 305.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 125.4" "Cancer enriched" "Detected in some" 72 "liver cancer: 151.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RH-30: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052324 Enhanced NA NA "HPA052324: AB_2681790" "unprognostic (4.23e-2)" "unprognostic (1.49e-2)" "prognostic favorable (5.42e-5)" "unprognostic (8.37e-2)" "prognostic favorable (3.79e-5)" "unprognostic (4.79e-2)" "unprognostic (6.46e-2)" "unprognostic (2.56e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 5.0 0.0 0.0 5.8 0.1 0.0 0.1 0.1 1.9 0.1 0.1 0.1 23.7 305.4 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 33.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.5 1.1 0.2 0.5 0.4 0.0 0.4 0.2 0.2 0.5 0.6 0.0 0.7 0.2 0.2 0.0 0.1 0.2 0.3 0.7 0.2 0.3 0.2 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.5 0.8 0.0 1.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.4 0.5 0.7 0.0 0.1 0.5 1.2 0.3 0.0 0.3 0.6 2.2 0.2 0.1 0.7 0.4 0.6 0.7 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.7 0.2 1.0 0.3 1.4 0.2 1.1 0.2 0.1 0.3 0.1 0.2 1.0 0.2 0.2 0.0 2.2 0.4 0.4 1.1 0.5 0.1 0.5 0.4 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 22.9 0.0 0.0 1.8 0.0 0.0 1.7 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 125.4 0.1 0.0 0.0 3.7 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 G6PC2 IGRP ENSG00000152254 "Glucose-6-phosphatase catalytic subunit 2" Q9NQR9 2 168901240-168910000 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "pancreas: 28.8;retina: 12.1" "Cell type enriched" "Detected in some" 13 "Muller glia cells: 70.6" "Cancer enriched" "Detected in single" 92 "pancreatic cancer: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;SCLC-21H: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (6.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.04e-2)" "unprognostic (9.05e-2)" "unprognostic (2.97e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-2)" "unprognostic (1.87e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 70.6 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070735-44076344 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA067052: AB_2685771" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favorable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavorable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" 25.4 38.1 25.8 15.6 25.4 11.1 23.4 12.9 35.3 25.3 17.8 37.8 28.3 21.1 22.0 50.9 14.4 27.7 20.5 22.2 25.4 37.8 42.8 15.3 18.7 29.8 32.9 21.3 28.1 29.1 38.4 37.7 22.2 34.0 26.1 15.2 37.4 27.7 33.8 22.9 9.9 17.7 17.8 33.1 19.7 18.2 20.7 16.0 18.5 35.1 11.4 14.8 21.4 14.0 5.9 33.4 3.1 19.0 7.2 6.1 6.5 10.2 61.3 21.4 34.5 22.8 17.0 15.1 11.7 24.2 27.6 18.5 25.3 16.6 23.6 17.0 26.2 19.0 17.7 16.3 25.1 13.2 12.1 25.2 13.0 41.5 46.1 23.7 11.6 16.4 22.3 12.1 26.1 18.4 16.8 22.8 10.1 13.3 30.1 20.6 28.6 5.7 18.0 26.8 13.4 39.9 11.9 13.4 54.7 37.4 24.1 25.8 22.8 13.0 15.6 15.0 25.3 43.0 11.8 22.8 27.3 14.5 7.3 16.3 20.1 14.3 6.7 30.4 10.2 34.7 1.2 15.2 3.1 4.6 19.0 5.6 5.5 3.6 4.4 24.6 5.9 4.6 6.1 0.5 7.2 11.1 33.4 3.5 6.5 25.8 25.4 12.9 35.3 25.4 37.8 32.9 21.3 34.0 16.0 3.0 11.7 11.1 13.2 2.3 9.0 5.9 15.3 16.0 13.6 38.4 11.8 55.8 11.6 46.4 3.3 15.6 15.1 0.0 43.1 32.6 15.4 16.0 17.4 5.0 51.3 4.8 22.1 18.4 20.6 4.0 18.7 18.3 13.5 22.6 12.2 34.1 31.2 14.0 21.5 29.3 7.9 12.9 8.6 27.2 28.1 2.3 35.6 8.2 16.9 12.9 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119879 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 125.7;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 23.8;eosinophil: 8.4;intermediate monocyte: 20.0;myeloid DC: 15.6;neutrophil: 10.8;non-classical monocyte: 24.7" "Group enriched" "Detected in all" 9 "dendritic cells: 15.6;granulocytes: 10.8;monocytes: 24.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 3000000 Vesicles "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 27.5 19.6 13.8 17.0 14.8 11.3 18.6 14.3 23.0 14.9 16.5 23.4 21.7 19.4 20.1 50.9 13.9 18.2 23.5 21.4 13.5 17.6 27.9 44.2 34.0 30.2 18.1 16.1 14.6 29.4 28.8 24.7 84.1 14.9 22.3 7.2 21.9 27.5 22.1 26.3 18.3 15.4 17.2 16.6 35.8 17.4 30.7 14.6 13.9 21.9 14.9 13.5 24.0 13.4 1.4 15.6 10.8 24.7 1.1 1.8 9.8 11.4 22.4 4.4 14.5 13.9 14.0 28.9 7.2 13.3 5.5 4.5 6.6 18.7 4.1 19.2 5.6 4.7 4.9 1.4 8.3 1.3 5.3 16.7 0.0 3.8 23.7 24.2 0.5 13.7 30.1 12.0 10.3 3.6 11.2 9.7 11.2 4.1 17.3 4.1 26.5 1.9 2.7 9.2 2.8 15.7 10.0 15.2 7.0 4.4 12.0 5.1 14.7 9.4 10.5 12.9 2.8 30.0 16.4 6.2 20.4 11.0 14.7 2.6 41.4 11.5 1.2 6.5 10.7 12.8 0.1 23.8 8.4 1.5 20.0 1.8 1.3 1.2 1.6 15.6 1.4 1.4 0.9 10.8 1.1 24.7 3.8 0.8 9.8 13.8 14.8 14.3 23.0 13.5 17.6 18.1 16.1 14.9 14.6 17.9 45.3 3.9 14.4 10.0 15.6 14.3 30.6 5.3 17.0 14.0 7.9 106.8 5.0 23.0 42.5 17.4 18.6 0.0 13.8 125.7 30.3 19.9 8.1 23.1 92.2 11.1 5.8 29.4 107.0 25.5 22.2 64.5 23.6 31.5 14.3 28.7 9.4 17.5 18.0 18.2 16.5 6.5 10.3 18.4 26.8 7.3 139.0 7.7 15.5 10.8 GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease mutation, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "granulocytes: 66.9;Kupffer cells: 62.6;Late spermatids: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 35.4;HMC-1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" NA NA 16000 "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" 13.8 17.7 21.2 13.2 32.2 18.9 15.4 16.3 25.5 12.3 15.8 28.8 9.6 30.3 10.7 12.1 6.5 20.1 17.4 19.6 22.0 19.5 20.5 11.1 23.0 18.0 30.7 20.1 17.3 13.6 14.4 12.6 15.6 24.9 14.1 16.9 13.3 8.9 10.1 9.3 9.4 30.2 9.3 33.8 14.3 14.9 21.6 26.1 8.6 23.5 5.8 7.3 12.6 11.4 1.7 5.7 20.8 10.5 9.4 16.3 6.4 0.0 8.3 3.1 0.0 10.3 9.3 0.0 3.8 7.7 3.6 4.3 4.5 35.4 2.2 11.5 3.7 0.0 0.5 0.0 0.4 4.4 1.1 0.2 12.2 0.3 0.0 8.5 0.0 33.5 9.1 2.8 2.4 0.0 1.5 9.7 0.0 4.0 1.7 6.0 0.8 0.0 1.8 2.8 14.5 0.9 0.0 0.2 0.1 5.7 3.3 2.9 6.7 10.4 1.7 0.0 7.7 8.6 8.4 8.2 0.0 5.6 2.4 0.0 1.8 3.3 0.0 1.0 2.8 8.0 12.8 9.5 20.8 7.5 10.5 16.3 1.7 5.7 7.2 5.7 0.8 4.2 4.9 7.8 9.4 8.0 1.0 3.2 6.4 21.2 32.2 16.3 25.5 22.0 19.5 30.7 20.1 24.9 26.1 23.8 21.3 10.5 4.6 7.4 10.4 9.9 15.3 9.4 7.9 14.0 11.8 4.7 3.3 8.0 38.1 11.3 12.4 0.0 9.9 9.6 10.8 7.8 66.9 5.0 23.9 3.2 5.8 18.4 62.6 61.8 15.0 19.6 10.1 27.1 13.0 9.0 11.8 14.8 9.6 5.8 10.6 0.0 7.2 10.0 8.7 10.0 5.5 20.0 12.9 5.7 GALNS "GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.1;granulocytes: 19.3;monocytes: 11.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433, HPA074225" Supported Approved Cytosol "Intracellular and membrane" NA NA 2400000 Cytosol "CAB026404: , HPA042433: AB_2732499, HPA074225: " "unprognostic (3.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (3.66e-4)" "unprognostic (4.15e-3)" "unprognostic (1.32e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (3.53e-2)" "unprognostic (4.12e-3)" "unprognostic (4.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" 11.9 14.9 9.3 11.2 11.1 25.0 14.8 12.9 15.4 11.1 15.5 11.5 8.8 13.3 9.0 19.9 10.2 14.8 12.7 12.5 11.2 13.9 13.7 17.8 14.7 10.6 11.8 5.2 11.9 7.3 9.9 13.2 15.6 11.6 10.5 8.3 7.1 10.6 9.0 7.1 10.0 17.2 9.4 9.4 10.4 9.5 27.4 8.8 7.9 14.5 6.1 9.0 11.1 13.0 2.1 7.1 19.3 11.2 2.4 3.1 4.7 2.5 19.6 2.8 20.1 22.7 10.9 19.7 8.2 12.8 9.0 7.0 10.2 17.0 3.2 17.4 13.4 13.6 15.1 4.1 6.5 5.5 2.1 6.5 2.0 8.0 5.8 15.3 1.5 13.3 15.2 12.7 10.1 2.8 12.9 7.7 3.5 4.4 1.9 5.3 15.0 4.1 6.5 6.6 6.5 9.1 8.7 2.5 5.4 5.6 6.0 7.4 5.7 19.5 1.8 9.7 7.2 12.7 14.4 14.4 19.8 15.1 20.2 4.5 2.0 1.9 5.5 21.5 13.3 11.7 0.9 11.2 19.3 3.1 8.0 2.6 2.1 1.8 2.7 7.1 0.9 1.7 2.1 14.2 2.4 5.6 3.0 3.0 4.7 9.3 11.1 12.9 15.4 11.2 13.9 11.8 5.2 11.6 8.8 14.9 4.5 1.9 6.4 5.8 3.9 6.7 2.5 26.8 7.9 3.5 5.9 7.9 3.3 5.3 14.3 4.9 12.3 0.0 3.0 11.4 10.2 5.7 1.1 5.7 17.8 23.8 11.5 7.4 13.9 28.0 6.6 8.0 6.8 20.8 6.9 8.5 5.4 12.4 6.3 4.5 9.7 6.5 9.2 49.5 33.7 5.0 13.3 5.7 8.6 5.1 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 37000000 "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" 33.6 34.6 16.2 23.3 20.7 17.9 30.1 19.9 31.0 38.9 31.5 29.8 43.4 26.0 44.0 38.6 29.2 34.2 33.8 32.6 17.2 16.5 35.9 91.5 31.4 30.2 21.7 19.5 49.0 51.4 56.6 27.3 61.1 20.0 29.4 32.6 33.7 43.5 40.7 28.2 24.5 39.8 37.4 19.5 37.4 31.2 27.7 20.2 41.8 45.6 25.2 34.0 36.0 29.4 14.6 17.5 16.5 18.8 22.5 20.0 17.6 42.5 37.3 46.7 84.6 72.1 63.1 50.6 48.0 72.1 66.5 57.5 31.1 79.2 29.2 97.1 84.8 52.9 58.2 56.3 53.9 68.9 23.5 24.3 28.8 51.2 12.9 53.3 44.6 36.3 61.2 35.0 66.1 69.4 84.2 61.6 30.0 40.8 52.7 59.7 37.4 23.2 14.5 39.5 35.0 30.3 31.0 56.0 73.3 32.6 34.8 24.7 33.5 68.6 44.5 51.1 52.5 58.3 38.1 46.3 66.6 42.6 52.2 44.6 52.9 61.2 22.3 73.1 24.0 64.7 16.5 15.0 14.4 20.0 18.8 20.0 14.6 13.8 15.9 17.5 13.1 17.9 16.3 7.0 22.5 16.4 11.6 13.0 17.6 16.2 20.7 19.9 31.0 17.2 16.5 21.7 19.5 20.0 20.2 11.9 26.8 19.7 22.3 25.1 29.5 6.5 61.1 10.7 7.9 64.6 56.9 71.8 5.0 43.0 15.3 31.5 35.1 0.0 36.9 114.6 43.7 31.3 10.5 80.2 51.7 33.4 30.6 51.5 41.2 11.0 54.1 24.9 33.7 36.9 50.5 40.2 38.3 25.9 64.0 24.2 33.9 32.3 26.7 18.4 48.6 27.4 67.1 24.2 55.2 26.0 GANC ENSG00000214013 "Glucosidase alpha, neutral C" Q8TET4 15 42273233-42356935 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Alveolar cells type 2: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016949, HPA051522" Approved Approved Cytosol NA NA Cytosol "HPA016949: AB_1849465, HPA051522: " "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (2.24e-1)" "unprognostic (3.04e-3)" "unprognostic (2.51e-2)" "unprognostic (9.85e-2)" "unprognostic (2.49e-2)" "prognostic favorable (9.76e-4)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (1.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (3.14e-1)" "unprognostic (1.55e-2)" "unprognostic (3.74e-2)" 13.3 14.0 12.5 17.3 20.7 17.6 14.4 16.6 14.2 15.8 14.3 25.6 15.4 11.7 17.9 26.0 20.7 12.9 13.0 12.4 13.4 10.4 13.5 18.0 30.5 13.8 25.0 13.7 18.8 13.1 17.4 20.5 10.8 19.8 13.1 17.8 18.3 20.4 13.7 23.9 13.9 15.4 15.9 25.1 15.5 13.1 24.5 22.6 17.4 16.8 12.3 18.3 16.2 16.3 17.6 12.2 9.3 10.1 4.0 7.4 4.7 6.2 3.2 7.9 8.6 9.6 13.6 5.0 13.7 14.8 15.1 12.7 4.7 4.4 3.4 7.5 13.8 10.5 13.0 9.5 14.6 10.5 8.5 4.4 8.5 8.6 9.2 8.1 8.2 7.4 9.2 8.7 6.1 10.5 8.5 10.2 8.7 8.8 9.6 11.9 1.3 5.5 9.1 4.9 2.7 4.2 10.6 9.3 11.8 11.4 5.8 6.0 8.5 7.7 6.7 4.8 4.5 2.5 19.4 9.2 15.9 4.2 13.1 8.2 10.4 13.7 6.9 7.5 15.1 8.7 9.3 9.3 7.4 3.7 10.1 5.0 16.2 5.7 6.9 12.2 17.6 7.4 4.4 5.0 4.0 8.1 9.6 5.5 4.7 12.5 20.7 16.6 14.2 13.4 10.4 25.0 13.7 19.8 22.6 17.9 36.3 8.3 15.1 9.3 5.1 6.9 2.5 12.0 10.3 1.8 9.8 4.4 5.0 4.3 9.0 4.0 8.4 0.0 3.3 4.2 4.5 6.5 10.4 9.0 6.0 3.2 4.1 7.4 11.6 3.0 6.6 10.3 13.5 11.8 5.5 10.4 5.0 16.5 6.0 6.3 6.5 12.9 5.2 14.2 14.4 4.5 2.4 5.0 7.5 21.3 GARS "CMT2D, DSMAV, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase" P41250 7 30594681-30634033 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 660000 Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavorable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.04e-5)" 25.8 27.3 24.5 26.2 28.5 24.6 32.4 31.1 44.7 21.5 23.7 17.0 11.5 17.2 24.1 23.3 43.7 18.6 18.4 25.7 21.1 26.8 27.6 57.2 27.9 28.0 22.9 28.4 35.4 49.4 44.4 33.3 24.3 37.6 17.2 30.2 14.1 28.7 21.6 35.6 33.2 18.1 30.1 17.6 23.5 30.5 29.7 14.9 28.6 31.4 33.9 38.4 22.8 25.7 22.5 26.4 21.2 27.2 15.3 27.6 21.2 33.5 16.6 14.8 52.3 27.6 41.5 28.0 50.2 45.5 25.9 52.5 22.1 16.8 56.5 15.2 61.1 40.7 26.6 36.8 31.9 45.6 13.5 17.2 26.1 13.6 18.6 87.7 38.4 23.1 39.5 56.0 37.1 44.1 18.4 33.2 52.5 51.7 65.9 41.1 20.7 33.4 26.6 39.8 31.0 31.8 16.9 13.0 43.9 29.7 15.2 17.8 29.9 13.4 37.6 71.4 27.6 33.5 58.9 30.4 12.3 41.3 24.7 31.7 65.2 54.6 66.5 43.0 58.2 57.8 21.2 19.0 17.7 23.2 25.8 23.7 22.5 23.7 25.1 26.4 19.3 25.5 27.6 5.6 15.3 27.2 18.0 25.9 21.2 24.5 28.5 31.1 44.7 21.1 26.8 22.9 28.4 37.6 14.9 38.7 27.4 35.6 34.3 29.9 23.3 30.7 25.5 14.7 27.3 19.2 21.6 41.1 28.2 79.9 48.1 24.6 13.9 0.0 131.2 61.8 33.2 32.2 40.3 27.0 39.9 17.5 25.2 31.9 25.5 44.0 21.6 32.4 32.1 57.7 36.9 20.2 111.3 7.0 21.5 31.8 15.7 12.9 30.0 71.9 80.1 24.1 33.3 25.4 22.3 44.7 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease mutation, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 101.2" "Cell type enhanced" "Detected in many" 4 "Hofbauer cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 200000 "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 19.2 29.7 14.8 13.9 24.5 21.9 15.3 8.7 33.4 16.5 20.1 25.2 18.1 13.8 16.9 30.4 18.9 12.7 16.5 13.6 15.8 18.9 31.8 24.6 17.9 15.4 18.5 16.5 13.1 19.2 101.2 32.1 46.2 28.1 14.4 23.5 25.3 22.3 24.3 6.0 21.6 16.6 17.7 19.3 24.5 14.6 9.7 13.1 13.7 22.2 8.7 17.5 16.3 15.2 7.3 13.9 17.9 22.3 6.6 14.0 12.4 8.5 16.6 5.9 8.0 62.2 13.7 6.8 15.2 54.1 22.7 28.7 9.7 31.5 5.9 16.9 35.6 36.4 17.5 8.3 10.8 12.1 12.5 5.8 4.9 11.0 5.2 17.8 5.8 20.8 17.9 9.1 47.7 7.2 24.0 20.1 5.2 5.2 10.1 26.6 18.6 7.2 2.7 3.8 14.1 11.8 6.1 9.7 24.4 15.2 6.6 5.7 7.8 13.3 31.9 33.7 11.4 23.9 14.2 15.3 17.1 7.6 21.4 12.1 20.2 17.0 4.6 29.9 5.3 13.1 12.2 21.6 9.1 13.4 22.3 8.7 7.3 10.3 9.0 13.9 5.5 7.4 7.8 17.9 6.6 21.2 7.8 14.0 12.4 14.8 24.5 8.7 33.4 15.8 18.9 18.5 16.5 28.1 13.1 3.0 3.2 4.5 5.7 5.4 3.4 7.9 17.8 6.7 2.3 12.2 2.0 27.5 3.3 26.2 1.1 11.3 17.3 0.0 28.1 23.9 12.9 8.2 6.9 20.7 57.7 4.8 14.0 20.9 39.9 2.2 9.2 13.9 25.3 28.9 13.1 13.2 25.6 19.8 8.5 17.0 5.4 0.0 6.7 4.8 5.7 3.9 49.7 9.6 11.6 4.3 GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 108.0;Rod photoreceptor cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: AB_1849530" "unprognostic (3.34e-2)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "unprognostic (3.99e-2)" "unprognostic (8.69e-2)" "prognostic favorable (6.00e-4)" "unprognostic (9.01e-3)" "prognostic favorable (1.24e-11)" "unprognostic (7.62e-3)" "unprognostic (2.94e-1)" "unprognostic (7.69e-2)" "prognostic favorable (6.60e-4)" 15.6 19.3 28.9 17.0 23.3 11.0 24.3 42.3 41.6 14.8 35.1 17.0 28.4 41.5 19.0 22.3 16.6 16.8 21.4 34.6 22.4 21.0 34.8 25.0 20.9 17.3 23.7 19.5 16.4 20.9 27.9 27.1 19.3 36.6 23.9 32.8 28.4 27.7 25.5 46.1 23.5 51.1 23.3 21.0 23.4 26.9 11.6 19.5 10.9 25.4 15.5 16.4 18.2 16.9 5.6 6.8 12.2 6.1 3.1 7.3 3.1 7.9 13.2 18.2 17.6 8.9 5.4 18.5 10.8 8.5 11.0 11.7 14.6 6.4 8.5 7.9 6.6 23.8 8.3 17.4 7.3 5.6 12.1 11.9 9.2 34.4 15.6 9.8 13.6 22.8 9.3 13.7 9.3 9.8 26.9 28.8 8.6 8.9 16.4 10.2 7.9 3.7 14.1 18.8 16.2 20.9 6.8 7.3 7.2 15.3 18.8 14.9 19.9 6.1 15.2 10.7 23.3 10.4 12.4 20.1 12.0 14.5 10.2 13.1 11.2 7.1 7.1 15.0 5.0 9.3 12.2 4.4 2.9 6.0 6.1 4.1 5.0 5.8 7.3 4.2 5.6 3.7 3.2 4.9 3.1 3.7 6.8 4.0 3.1 28.9 23.3 42.3 41.6 22.4 21.0 23.7 19.5 36.6 19.5 11.9 10.1 8.0 16.1 6.5 73.4 10.9 20.4 21.4 14.8 26.2 108.0 8.7 18.3 9.9 12.7 13.7 68.4 0.0 10.4 7.6 7.4 14.9 13.9 16.3 7.9 49.3 34.3 26.4 15.4 17.0 11.5 10.1 11.8 7.2 32.8 15.5 12.6 56.1 9.2 16.5 95.2 12.9 9.9 8.6 4.9 8.7 18.5 12.5 30.3 22.5 GCH1 "DYT14, DYT5, DYT5a, GCH, GTPCH1" ENSG00000131979 "GTP cyclohydrolase 1" P30793 14 54842008-54902852 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" "Allosteric enzyme, Hydrolase" "Disease mutation, Dystonia, Parkinsonism, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.8;liver: 58.2" "Cell type enhanced" "Detected in many" 12 "Hepatocytes: 82.5;Intestinal endocrine cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 11.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 11.8;Daudi: 13.3;SH-SY5Y: 29.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 15.7" HPA028612 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No Nucleoplasm "Nuclear membrane, Cytosol" "HPA028612: AB_10602135" "unprognostic (3.77e-2)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (2.39e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.75e-1)" "unprognostic (3.97e-1)" "prognostic favorable (8.69e-4)" "prognostic favorable (1.41e-4)" "unprognostic (1.23e-1)" "unprognostic (1.96e-2)" "unprognostic (7.22e-3)" "unprognostic (1.76e-2)" "unprognostic (2.23e-1)" "prognostic favorable (6.67e-4)" 4.8 5.2 1.3 5.7 4.5 26.8 2.1 0.6 1.1 2.2 5.5 1.2 1.5 7.5 1.8 1.9 3.8 1.3 1.6 1.5 1.6 4.3 7.9 58.2 11.6 6.7 2.9 0.7 1.4 3.2 0.3 2.5 2.5 2.8 2.9 4.0 5.2 2.5 4.7 1.4 2.5 9.1 2.0 1.7 10.0 4.2 3.6 1.1 13.0 2.3 2.0 8.5 2.9 2.5 1.6 3.0 0.4 11.5 2.3 3.2 1.3 1.9 0.6 0.7 3.5 0.0 0.0 11.8 0.0 1.2 0.8 2.2 0.9 0.6 13.3 3.3 0.1 1.8 2.0 5.7 0.9 0.0 5.2 5.0 0.3 0.2 1.9 5.7 0.0 1.2 1.4 1.6 1.9 0.0 0.0 0.4 9.1 0.8 0.0 0.0 6.8 7.2 0.2 1.1 2.9 4.5 5.9 1.4 0.0 1.7 2.8 5.9 29.7 2.5 1.5 0.7 0.3 5.7 1.6 0.2 0.1 2.0 3.7 2.3 5.7 4.3 3.2 2.5 4.6 0.0 0.0 3.0 0.2 3.0 6.3 2.5 0.8 1.6 2.1 3.0 1.6 3.2 1.8 0.4 2.3 11.5 0.1 2.3 1.3 1.3 4.5 0.6 1.1 1.6 4.3 2.9 0.7 2.8 1.1 3.0 4.5 8.1 28.1 66.2 0.0 3.3 5.1 2.7 7.9 5.2 2.0 1.8 6.6 8.3 0.4 11.7 16.0 23.3 8.1 40.5 8.2 17.3 0.0 82.5 5.6 0.0 203.8 6.2 24.0 0.6 0.3 13.3 10.1 6.4 15.2 0.3 9.8 14.0 4.6 38.4 0.2 0.0 15.5 1.1 4.7 66.6 3.5 22.3 8.9 32.9 GDA ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8;intestine: 54.5;liver: 27.6" "Group enriched" "Detected in many" 7 "Enterocytes: 113.2;Hepatocytes: 49.7;Paneth cells: 91.2;Proximal tubular cells: 84.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 11.1;EFO-21: 44.1;HeLa: 15.4;hTCEpi: 20.6;OE19: 50.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "amygdala: 39.7;basal ganglia: 31.5;cerebral cortex: 63.2;hippocampal formation: 79.5;olfactory region: 28.4" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm No NA 1300000 Nucleoplasm "HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351" "unprognostic (2.64e-2)" "unprognostic (7.10e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (4.35e-2)" "unprognostic (8.45e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "prognostic favorable (2.66e-5)" "unprognostic (2.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (8.30e-4)" 0.5 1.7 26.7 1.8 27.7 0.5 0.5 0.4 33.8 1.0 20.6 0.9 7.7 47.4 2.4 0.6 0.5 4.7 13.1 0.5 25.7 15.0 21.4 27.6 0.5 0.5 2.9 27.4 0.4 1.7 10.8 1.7 10.3 0.8 0.4 5.5 0.0 0.4 4.1 1.1 1.6 54.5 0.5 0.6 0.5 2.0 1.0 0.2 0.0 0.4 1.0 2.6 3.4 0.5 1.4 0.5 3.0 0.7 1.0 1.0 0.1 11.1 1.4 0.0 0.0 0.0 0.0 0.2 0.0 8.1 0.0 0.0 1.0 6.3 0.0 44.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.2 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 50.0 0.0 0.0 0.0 0.3 0.3 2.5 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.0 0.7 0.3 1.0 0.6 0.3 0.6 0.5 0.4 0.3 1.4 0.7 0.7 1.9 1.0 0.4 0.5 0.5 0.1 26.7 27.7 0.4 33.8 25.7 15.0 2.9 27.4 0.8 0.2 0.0 0.3 1.7 0.5 0.0 0.0 0.6 12.7 0.0 0.0 0.0 0.0 0.1 3.3 9.2 1.0 0.0 113.2 0.0 9.7 1.0 0.4 0.6 0.0 49.7 0.2 0.0 4.6 1.3 1.0 0.0 0.3 0.0 0.0 1.0 11.2 0.0 4.4 91.2 0.0 84.2 0.0 0.0 0.3 0.4 4.2 0.1 1.6 0.0 7.8 0.8 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501689-19522145 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Syncytiotrophoblasts: 226.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved Vesicles NA NA Vesicles "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 20.3 18.5 30.6 11.7 34.3 17.5 23.9 13.5 32.2 18.1 31.0 24.5 23.0 22.7 15.0 22.6 19.0 13.4 17.5 40.7 31.1 17.5 21.1 21.3 22.1 13.1 29.2 20.6 9.9 28.3 35.3 13.9 15.5 20.8 21.4 32.5 12.5 20.4 24.9 42.4 18.5 20.8 27.2 25.3 10.1 22.8 14.8 23.8 9.6 17.9 21.7 12.7 22.8 12.4 4.6 7.4 23.9 12.4 3.7 7.4 4.6 14.8 17.9 9.8 11.7 47.6 17.6 14.2 15.4 26.4 12.0 14.9 10.2 26.6 11.1 19.8 22.3 13.2 12.9 13.7 18.1 14.6 12.1 21.2 9.3 17.6 21.9 28.9 12.2 8.7 18.5 29.4 12.8 15.0 22.3 16.1 14.5 5.1 11.6 13.0 26.8 10.7 11.3 11.5 23.3 13.9 15.4 18.1 16.1 29.7 22.8 11.5 10.5 14.9 17.9 14.2 15.9 18.3 14.7 16.9 10.2 9.1 13.4 9.4 10.9 10.2 7.8 15.6 18.2 9.0 23.9 11.8 6.4 5.7 10.5 7.3 4.6 6.8 6.6 7.4 3.7 3.6 5.7 19.8 3.7 12.4 4.6 7.4 4.6 30.6 34.3 13.5 32.2 31.1 17.5 29.2 20.6 20.8 23.8 35.7 72.1 27.9 29.4 20.8 14.8 63.5 35.7 26.8 26.1 8.7 25.5 63.8 19.9 79.5 27.6 16.8 94.2 23.3 143.1 66.0 28.2 77.4 3.5 20.0 53.4 30.2 32.1 17.8 30.7 51.5 26.4 32.5 23.6 22.6 50.6 19.8 66.9 87.7 35.7 39.2 21.5 12.9 25.5 71.0 39.2 25.7 226.1 21.8 61.0 49.4 GDPD1 "FLJ37451, GDE4" ENSG00000153982 "Glycerophosphodiester phosphodiesterase domain containing 1" Q8N9F7 17 59220467-59275967 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.3" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 28.4;Spermatocytes: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 22.6;K-562: 12.8;SCLC-21H: 14.3" "Low region specificity" "Detected in all" NA NA "unprognostic (8.33e-2)" "unprognostic (6.63e-3)" "unprognostic (2.68e-2)" "unprognostic (5.98e-3)" "unprognostic (7.12e-2)" "unprognostic (5.35e-2)" "unprognostic (4.85e-6)" "prognostic favorable (2.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.36e-2)" "unprognostic (1.24e-3)" "unprognostic (2.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-3)" "unprognostic (4.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.28e-3)" 1.5 3.6 9.4 1.8 13.1 2.3 3.5 16.6 22.3 2.5 3.9 9.2 0.9 10.7 2.8 1.9 1.7 3.2 3.8 2.2 10.6 13.2 4.2 2.0 4.3 1.7 9.3 10.3 2.2 2.3 14.8 3.1 9.2 15.1 4.4 3.1 2.0 4.1 3.0 2.6 2.8 7.8 2.9 7.1 2.8 10.4 13.0 8.9 3.2 5.5 0.3 2.0 3.6 1.7 1.5 2.9 4.5 3.0 3.0 3.5 1.0 0.8 1.4 4.8 3.5 0.6 0.5 3.6 0.5 1.9 0.7 3.6 0.0 1.7 2.2 5.2 0.1 2.9 0.7 8.1 1.0 2.1 4.0 8.4 22.6 0.5 3.2 1.8 1.3 4.4 0.8 4.9 2.0 0.5 2.3 2.6 5.2 12.8 1.3 0.8 0.8 3.9 0.3 1.0 7.0 1.2 2.7 0.4 2.1 2.5 1.4 14.3 4.2 1.4 0.4 5.4 1.7 4.0 1.4 3.0 0.2 1.6 0.1 0.5 4.3 3.1 0.8 1.2 1.5 2.1 4.5 1.9 0.8 2.2 3.0 1.7 0.7 2.2 3.2 0.9 1.5 3.0 3.5 2.0 3.0 2.3 2.9 1.2 1.0 9.4 13.1 16.6 17.7 10.6 13.2 9.3 10.3 15.1 8.9 3.0 5.1 0.0 1.1 0.5 5.8 2.4 0.0 6.7 12.5 5.2 9.8 0.2 0.0 1.6 28.4 1.1 1.3 0.0 1.6 4.9 0.4 1.2 0.0 0.4 1.6 6.4 1.2 0.6 1.0 5.1 0.6 1.8 1.7 2.8 1.2 1.7 1.5 2.0 1.4 0.3 3.8 0.0 1.2 31.7 4.3 0.4 1.9 1.5 0.9 1.4 GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 22.5;intestine: 19.5;lymphoid tissue: 37.5;skin 1: 33.2" "Cell type enhanced" "Detected in some" 16 "Basal keratinocytes: 50.5;Enterocytes: 47.9;Muller glia cells: 24.7" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "AF22: 9.4;NTERA-2: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" 0.4 0.4 6.8 0.6 5.7 0.4 1.0 1.1 4.0 0.3 13.0 8.2 8.3 8.0 0.4 22.5 0.4 0.5 0.5 0.8 7.6 4.0 0.6 0.3 0.4 0.4 4.3 5.6 0.4 0.4 0.3 2.6 0.4 8.4 0.3 3.0 0.2 1.1 0.6 0.6 33.2 19.5 0.4 1.5 37.5 1.6 0.3 4.9 0.0 0.4 0.6 0.3 1.0 0.3 0.4 0.1 1.4 0.2 0.1 0.2 0.0 0.0 0.0 9.4 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 20.2 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 0.4 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.0 6.8 5.7 1.1 4.0 7.6 4.0 4.3 5.6 8.4 4.9 0.0 0.0 0.0 0.0 50.5 0.1 1.4 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 3.1 0.5 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 24.7 0.1 2.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 10.7 2.7 0.0 1.5 0.1 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63015079-63039171 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 42.5;liver: 59.5" "Cell type enhanced" "Detected in many" 10 "Cytotrophoblasts: 501.9;Early spermatids: 395.4;Syncytiotrophoblasts: 631.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in all" 4 "dendritic cells: 18.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" NA NA 1400000000 "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 3.5 3.6 7.4 4.7 8.6 12.3 11.8 15.5 9.9 3.5 17.6 1.5 1.0 3.7 2.6 3.7 11.0 1.6 2.8 5.9 7.9 7.6 42.5 59.5 3.5 5.0 4.7 7.0 1.9 4.2 1.0 1.6 17.7 14.8 1.9 26.4 2.2 6.5 1.8 1.7 11.1 3.6 4.2 7.6 3.7 3.2 14.0 3.8 5.2 1.4 14.5 7.6 3.9 6.6 4.1 18.2 2.1 1.9 2.9 1.4 1.4 20.0 19.3 19.8 3.0 19.5 8.2 14.6 12.4 21.2 19.7 28.5 27.0 35.6 13.7 3.5 15.3 33.2 16.8 19.6 20.7 29.2 27.8 14.8 22.5 10.4 18.2 3.7 10.5 13.5 6.0 5.9 19.8 9.5 12.5 23.7 14.0 12.0 50.3 36.8 11.3 5.1 10.5 9.3 44.9 18.3 15.3 19.3 18.4 15.2 7.0 7.9 13.6 18.0 19.7 18.8 19.1 21.7 11.7 12.5 21.2 23.8 20.3 22.2 23.6 24.0 16.1 32.7 0.0 37.3 0.0 1.9 2.1 1.1 1.1 0.5 4.1 1.3 1.3 0.6 1.9 1.0 1.3 1.8 2.9 1.2 18.2 1.4 1.4 7.4 8.6 15.5 9.9 7.9 7.6 4.7 7.0 14.8 3.8 14.9 8.2 22.6 16.2 26.9 1.7 1.6 17.8 14.7 14.8 21.0 0.0 501.9 31.5 20.1 395.4 8.3 17.2 46.7 6.4 234.3 29.8 8.2 10.4 171.3 65.1 0.0 12.7 15.4 18.7 97.7 5.5 15.0 23.6 54.1 74.6 20.3 6.2 8.6 7.8 214.6 1.1 25.8 10.8 73.7 141.6 37.6 631.0 10.1 104.6 12.5 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24583750-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 54.1;seminal vesicle: 41.7" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 74.5;Alveolar cells type 2: 21.4;Cholangiocytes: 40.8;Ductal cells: 54.8;Enterocytes: 80.7;Hepatocytes: 34.1;Pancreatic endocrine cells: 33.5;Paneth cells: 23.0;Proximal tubular cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 35.6;Karpas-707: 52.5;OE19: 37.9;RPMI-8226: 51.6;RPTEC TERT1: 48.0" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 4600000 Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 1.6 0.5 1.7 1.7 2.2 2.7 8.2 2.3 2.6 7.3 7.9 1.6 23.7 22.3 1.4 19.9 1.2 0.8 12.2 2.0 1.8 1.2 54.1 29.2 14.3 3.2 1.7 1.6 1.3 17.3 0.0 1.6 1.4 2.2 14.7 2.4 1.4 8.7 41.7 0.9 1.1 20.9 1.7 1.9 4.7 6.6 5.0 2.1 2.4 4.8 1.6 5.5 2.1 1.1 3.3 7.5 15.9 14.6 6.6 8.6 6.6 0.2 19.3 0.2 0.0 0.0 0.1 0.5 0.1 0.6 0.2 0.2 2.6 4.2 0.2 4.3 0.0 3.8 2.8 1.4 0.2 0.1 35.6 2.9 0.1 8.6 14.0 1.5 0.3 11.9 0.4 0.2 0.6 0.4 0.3 0.1 5.3 2.0 52.5 0.2 0.4 0.3 14.6 1.4 37.9 0.2 0.2 2.2 51.6 48.0 0.6 0.2 0.3 0.1 9.3 0.2 5.5 9.3 11.1 2.2 3.5 2.3 10.8 0.3 15.8 5.9 0.2 7.4 15.0 0.1 5.2 14.6 0.4 1.4 6.8 5.2 3.3 7.7 3.4 7.5 0.3 1.0 1.9 15.9 6.6 5.5 0.1 8.6 6.6 1.7 2.2 2.3 2.6 1.8 1.2 1.7 1.6 2.2 2.1 74.5 21.4 3.4 0.1 0.7 0.4 0.4 40.8 2.7 7.9 1.8 0.0 0.9 1.7 54.8 1.1 0.1 80.7 0.0 7.2 0.3 1.3 3.0 5.7 34.1 4.7 0.0 1.2 2.5 3.0 4.1 0.0 2.9 1.7 5.4 2.5 2.0 33.5 23.0 0.4 32.7 0.0 0.0 0.2 0.6 0.7 0.4 0.7 3.2 4.2 0.0 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245142 "Enzymes, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 19 "Ito cells: 44.2;Sertoli cells: 181.1;Smooth muscle cells: 82.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.0;eosinophil: 7.5;neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 7.5" "Group enriched" "Detected in some" 4 "ASC diff: 39.5;ASC TERT1: 30.1;HHSteC: 56.4;HSkMC: 65.0;TIME: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 18000000 "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 20.2 14.8 2.0 5.2 3.5 0.0 13.2 0.5 4.2 10.7 4.0 5.7 7.9 3.6 2.1 10.2 12.1 14.0 2.4 3.4 13.1 13.7 5.1 12.4 4.7 3.9 5.0 2.2 6.0 3.2 6.5 3.4 5.4 6.8 2.5 5.3 7.2 10.1 2.7 4.8 5.6 1.2 17.2 5.2 6.3 9.3 0.1 0.4 7.5 0.9 0.8 0.1 0.4 0.0 0.3 0.0 0.0 39.5 30.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.1 5.2 56.4 0.6 1.4 65.0 0.0 0.7 0.7 0.0 10.6 0.1 0.1 0.1 10.1 0.1 0.0 4.9 0.6 0.1 0.0 0.0 0.9 0.1 1.1 0.0 0.0 1.4 0.0 1.7 0.0 5.6 0.2 0.3 25.2 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.1 0.0 4.0 0.9 7.5 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.9 0.8 0.0 0.1 0.0 0.4 3.0 16.5 0.5 3.1 6.3 0.0 4.8 0.0 2.7 11.4 0.0 0.0 0.2 0.0 0.1 0.5 37.5 0.0 0.0 0.2 0.1 8.7 1.3 1.1 0.0 1.6 0.0 0.0 44.2 1.2 2.6 33.6 2.9 3.3 5.4 0.0 0.2 0.3 0.0 22.3 0.0 0.4 181.1 82.1 0.3 0.4 3.9 0.2 0.0 0.0 0.9 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;salivary gland: 52.7" "Cell type enhanced" "Detected in many" 10 "Enterocytes: 136.8;Mucus-secreting cells: 63.3;Paneth cells: 98.2;Undifferentiated cells: 77.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.5" "Group enriched" "Detected in some" 8 "RT4: 30.5;SK-BR-3: 10.4;T-47d: 32.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 33000 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.4 0.3 12.7 0.3 0.0 3.2 0.3 0.4 4.1 24.9 0.4 1.0 17.0 0.9 15.9 25.2 3.0 7.7 0.3 0.3 0.1 18.8 0.6 4.2 0.3 0.3 0.3 1.5 28.6 0.0 1.0 0.4 0.4 5.7 12.7 0.4 52.7 3.7 0.3 25.2 40.4 2.8 0.3 0.3 8.7 0.8 0.3 1.0 0.7 19.6 18.8 16.5 8.2 0.6 0.7 3.5 0.5 0.6 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 30.5 0.1 0.1 0.0 10.4 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.5 0.2 0.4 0.3 0.2 0.3 0.5 0.3 0.1 0.6 0.5 0.4 1.9 0.6 0.5 0.7 0.4 0.0 0.3 0.3 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.3 32.8 5.8 2.2 16.1 3.7 0.0 0.2 17.8 33.5 29.6 22.7 2.0 0.0 18.3 16.4 0.0 0.0 136.8 0.0 33.4 0.0 0.3 3.4 0.0 0.0 0.1 0.0 5.8 0.0 0.0 0.0 0.6 1.3 0.0 3.6 63.3 0.2 14.4 98.2 0.0 32.1 0.2 0.0 1.0 0.0 0.1 18.2 0.0 0.5 77.9 19.7 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872860 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Bipolar cells: 38.6;Horizontal cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 1500000 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: AB_2668816" "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 6.8 6.7 21.6 6.7 23.7 2.9 8.5 42.6 29.1 9.5 11.5 9.7 14.3 9.8 12.3 19.5 6.4 10.5 11.4 13.8 19.7 17.0 9.9 7.2 9.0 10.3 11.2 32.1 13.4 19.5 20.8 18.3 8.5 19.2 11.4 9.6 6.9 18.8 15.3 31.6 11.1 9.0 9.6 11.0 8.3 12.9 5.0 15.6 4.9 16.3 4.3 8.2 9.3 8.5 6.1 2.6 1.5 3.0 3.2 12.8 1.8 2.2 3.3 17.0 17.4 13.4 12.0 15.1 9.4 9.6 7.8 11.6 17.4 11.1 0.0 11.2 7.3 7.9 1.5 7.3 4.1 5.1 0.7 13.1 6.7 5.9 9.1 12.0 0.3 11.1 17.4 4.7 8.7 4.0 23.3 0.6 8.9 5.0 1.2 5.3 3.8 1.7 3.4 3.9 3.8 1.7 0.0 11.6 10.7 11.3 3.3 9.9 11.6 4.8 7.7 12.1 6.7 5.9 6.1 0.2 26.8 10.7 2.5 5.3 13.1 1.7 0.8 31.5 0.6 9.8 1.5 3.0 1.4 7.4 2.0 2.1 5.6 6.3 2.8 2.6 6.1 12.8 8.9 0.3 3.2 0.7 1.4 4.8 1.8 21.6 23.7 42.6 29.1 19.7 17.0 11.2 32.1 19.2 15.6 3.0 2.4 0.9 17.1 6.5 38.6 1.6 22.9 1.4 3.4 17.4 11.8 18.6 0.0 13.9 2.1 2.1 10.5 0.0 4.9 9.8 11.9 9.2 2.3 10.2 4.0 38.1 10.4 0.6 1.9 0.5 11.5 2.4 10.1 3.6 16.0 9.4 6.7 14.0 7.4 5.1 16.9 6.5 8.6 11.1 10.6 3.8 14.1 4.1 17.8 12.0 GLA GALA ENSG00000102393 "Galactosidase alpha" P06280 X 101397803-101407925 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Hofbauer cells: 85.3;Melanocytes: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000237, HPA000966" Enhanced "Intracellular and membrane" NA NA 910000 "HPA000237: AB_1078968, HPA000966: AB_1078969" "unprognostic (7.27e-3)" "unprognostic (1.47e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (5.62e-5)" "unprognostic (2.53e-1)" "unprognostic (3.42e-1)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-2)" "prognostic favorable (6.16e-4)" "unprognostic (1.13e-1)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" 21.1 22.2 5.2 10.0 6.3 15.6 19.2 6.2 5.7 10.8 12.7 7.3 23.2 14.8 11.7 14.1 9.4 11.5 9.1 10.5 5.2 6.3 28.7 18.9 18.7 12.0 9.4 3.2 9.7 8.3 9.8 10.5 17.9 8.6 8.3 11.2 9.4 9.5 47.7 5.9 8.9 21.3 10.8 11.9 20.8 8.5 4.9 5.8 10.2 8.3 13.4 11.2 12.2 8.9 5.4 15.9 12.8 20.9 3.0 6.1 10.1 7.2 28.4 8.2 8.4 19.0 7.4 3.7 8.3 13.0 15.9 45.3 15.4 11.2 8.0 17.7 8.5 37.5 17.3 16.1 9.0 13.8 4.9 12.0 4.4 23.6 18.1 4.9 6.1 81.0 6.5 2.9 18.3 5.3 4.4 12.8 4.9 6.8 17.7 15.1 12.9 6.1 12.7 12.0 17.3 11.5 4.4 10.1 19.5 23.2 14.7 3.0 5.1 19.3 8.2 7.7 14.2 3.8 12.6 7.3 5.5 6.6 13.1 6.7 5.4 6.2 6.1 9.5 10.2 6.1 9.5 20.8 6.2 4.6 20.9 6.1 5.4 3.7 5.7 15.9 4.9 3.8 4.7 12.8 3.0 20.8 6.7 4.3 10.1 5.2 6.3 6.2 5.7 5.2 6.3 9.4 3.2 8.6 5.8 14.9 12.2 18.9 23.0 26.9 3.8 6.7 0.0 22.7 17.0 10.4 5.9 35.6 14.9 19.5 2.6 19.0 23.9 0.0 16.1 22.7 43.3 16.3 30.1 5.7 85.3 7.9 32.5 5.5 21.1 0.8 10.3 80.3 84.4 37.9 6.8 17.7 15.1 17.5 17.0 7.9 4.6 6.5 71.0 6.0 5.5 20.7 63.2 10.7 12.3 13.2 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996608-33097230 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 139.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 1700000 Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 17.3 33.1 9.6 14.9 14.7 9.5 18.4 8.9 19.8 18.3 21.9 12.1 19.8 21.2 18.3 55.0 12.7 15.2 25.8 13.7 9.7 10.0 35.0 33.2 24.3 25.0 9.2 9.7 18.3 25.3 28.4 16.4 26.5 14.0 13.6 23.7 23.5 21.1 17.7 6.1 12.9 28.3 15.6 9.8 21.4 22.7 10.0 8.0 8.3 26.9 7.7 19.5 18.4 13.6 11.1 45.2 22.7 39.2 6.8 20.9 20.9 5.8 10.0 6.5 7.7 39.9 20.7 139.7 9.3 25.2 12.0 15.4 14.2 13.8 2.8 8.3 19.0 8.9 5.6 6.1 11.9 8.9 16.3 5.1 11.2 6.0 7.3 20.5 7.7 11.4 23.9 11.4 10.8 6.4 23.6 18.4 3.9 10.1 10.9 13.1 6.8 4.6 5.1 4.4 12.2 4.4 4.0 4.3 13.2 12.9 8.5 2.0 6.8 12.0 19.4 11.7 12.0 12.9 20.4 10.7 7.7 5.4 10.5 7.9 8.6 13.7 0.9 16.2 11.2 5.8 10.5 39.2 22.7 8.3 34.6 11.8 11.1 10.2 9.1 45.2 10.0 5.4 6.5 15.5 6.8 23.7 9.5 20.9 20.9 9.6 14.7 8.9 19.8 9.7 10.0 9.2 9.7 14.0 8.0 17.9 22.3 15.9 10.2 5.4 11.3 7.1 35.7 14.7 17.0 26.2 5.9 80.5 23.2 42.1 22.3 10.5 31.5 0.0 31.3 47.6 24.4 11.4 26.5 36.5 70.6 4.8 16.3 18.4 38.2 3.1 14.1 38.3 13.5 81.2 22.4 20.0 27.0 39.5 19.8 24.2 15.0 12.9 10.8 1.1 7.2 3.0 41.1 20.0 28.4 8.4 GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880827-190965552 "Enzymes, Predicted intracellular proteins" Hydrolase "Cataract, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 127.9" "Cell type enhanced" "Detected in all" 6 "Collecting duct cells: 371.6;Proximal tubular cells: 372.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 141.8;RPTEC TERT1: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" No No 25000 Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" 16.5 37.3 37.8 20.4 24.7 10.7 34.3 43.8 47.3 11.9 13.1 5.8 8.9 36.9 14.6 11.9 7.6 11.0 17.7 15.7 23.3 22.8 127.9 5.3 22.6 25.4 20.6 36.8 14.1 17.0 26.4 10.1 14.8 35.1 9.4 13.1 10.8 9.0 13.9 7.4 13.0 40.9 15.5 11.7 19.3 8.7 6.9 12.1 15.0 17.7 8.0 22.9 14.1 16.1 5.2 5.0 6.0 2.1 3.9 9.4 1.5 6.4 7.1 5.0 6.6 15.7 11.0 13.0 19.2 14.6 14.0 16.1 8.7 6.4 13.2 141.8 40.5 7.1 8.4 8.8 7.5 20.6 32.5 5.7 21.9 10.5 10.7 14.4 12.7 10.3 9.9 7.9 11.0 7.5 14.0 18.1 5.5 10.1 26.9 31.1 3.4 8.6 12.3 13.4 3.8 11.7 11.0 12.9 11.4 65.2 11.8 6.9 7.2 26.2 5.8 24.4 18.7 2.3 7.9 12.9 20.3 14.9 10.1 23.2 8.7 19.8 18.1 7.3 10.5 16.1 6.0 1.5 2.5 5.5 2.1 9.4 4.8 6.5 7.0 2.2 5.2 6.8 8.1 3.0 3.9 1.4 5.0 5.6 1.5 37.8 24.7 43.8 47.3 23.3 22.8 20.6 36.8 35.1 12.1 175.7 95.7 52.1 47.3 155.0 91.0 32.2 30.6 16.0 40.9 371.6 198.3 3.3 43.1 22.6 4.4 51.8 120.5 23.3 20.9 10.2 63.7 42.0 35.8 4.9 25.8 25.4 56.7 57.7 27.2 3.6 26.4 55.5 84.4 88.4 25.7 10.0 29.5 31.6 40.7 372.1 117.6 19.4 70.9 10.7 11.0 142.3 3.3 62.3 28.1 52.1 GLS2 "GA, GLS, hLGA, LGA" ENSG00000135423 "Glutaminase 2" Q9UI32 12 56470944-56488414 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 92.2" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 52.1" "Cancer enhanced" "Detected in single" "liver cancer: 1.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 29 "B-cells: 1.8;T-cells: 3.8" "Cell line enhanced" "Detected in some" "Daudi: 25.6;RPMI-8226: 4.6;SCLC-21H: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038608 Uncertain NA NA "HPA038608: AB_10673176" "unprognostic (5.59e-2)" "unprognostic (1.51e-2)" "unprognostic (8.73e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "unprognostic (3.27e-3)" "unprognostic (1.98e-6)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (5.65e-5)" "unprognostic (1.42e-2)" "unprognostic (2.59e-1)" "unprognostic (9.02e-2)" "unprognostic (4.44e-2)" 0.9 1.7 5.7 1.0 8.6 0.9 1.4 12.8 15.0 1.0 1.2 0.2 0.0 1.0 1.2 2.0 1.4 2.8 0.9 1.0 4.2 4.1 1.6 92.2 1.4 1.2 1.9 9.7 1.2 15.8 3.0 6.2 0.8 8.6 1.4 1.7 2.5 1.4 2.0 0.9 2.0 1.0 1.1 3.2 1.1 1.4 1.1 1.4 0.0 1.4 0.0 1.4 1.1 0.8 1.8 0.0 0.0 0.0 0.0 3.8 1.4 4.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.5 0.9 25.6 0.5 0.0 0.0 0.6 0.0 3.8 0.0 0.0 3.8 0.0 0.3 4.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.8 0.8 0.4 0.0 0.1 4.6 2.7 1.8 7.3 0.4 0.8 0.3 0.0 0.7 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.3 1.8 3.3 1.0 0.0 0.6 3.8 3.5 0.0 0.0 0.0 0.0 0.6 1.4 5.7 8.6 12.8 15.0 4.2 4.1 1.9 9.7 8.6 1.4 0.0 2.4 1.9 4.2 1.4 9.5 0.0 0.0 2.7 6.8 0.0 5.9 0.1 6.6 0.4 0.0 0.3 0.0 0.0 1.6 0.0 0.1 1.5 1.1 52.1 0.1 3.2 1.2 1.3 1.5 0.0 0.9 0.0 1.7 0.0 0.0 2.3 0.8 0.0 0.0 0.5 10.2 0.0 0.0 0.0 1.0 1.0 0.2 0.0 0.2 0.3 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 55.0;salivary gland: 45.3" "Cell type enhanced" "Detected in many" 9 "Hepatocytes: 95.4;Mucus-secreting cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favorable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 7.7 6.7 6.0 6.5 8.3 8.3 16.6 11.1 12.1 7.9 20.7 7.0 4.6 2.9 8.0 3.9 7.6 6.7 5.2 7.6 7.8 6.8 6.8 55.0 5.5 6.0 6.0 7.8 9.8 8.4 4.1 7.0 20.2 10.2 10.1 30.1 4.8 45.3 5.0 10.5 3.7 7.2 11.7 10.9 4.5 4.9 3.4 5.3 3.2 4.6 4.2 7.9 8.6 7.9 3.9 2.2 1.2 2.7 2.4 4.2 1.8 4.4 19.9 8.9 7.6 10.1 10.1 12.9 6.2 7.9 8.6 11.1 4.8 14.2 5.8 6.6 10.3 22.4 1.7 6.7 2.0 9.6 10.9 0.6 5.0 11.7 6.6 6.9 0.1 14.3 6.6 2.0 14.3 13.5 6.3 3.6 9.0 6.3 12.1 8.3 0.7 8.1 2.6 5.1 2.8 11.2 6.7 7.5 1.6 47.6 8.2 7.6 6.9 6.6 2.3 5.7 3.3 2.1 5.1 5.2 5.7 5.9 6.8 5.4 5.3 11.3 3.2 7.8 4.3 8.1 0.7 1.7 0.9 2.7 2.2 1.8 2.4 3.4 2.9 1.4 3.9 4.0 4.2 1.2 2.4 2.7 2.2 1.5 1.8 6.0 8.3 11.1 12.1 7.8 6.8 6.0 7.8 10.2 5.3 8.9 10.6 4.5 2.8 1.6 7.9 5.9 10.2 18.7 14.8 8.7 5.9 7.5 1.7 9.3 2.8 4.5 18.3 0.0 5.2 7.3 5.1 7.6 9.3 95.4 2.7 11.1 11.1 8.0 5.0 2.3 10.0 4.3 1.7 6.4 67.2 2.0 4.2 23.0 6.0 1.7 6.2 12.9 4.1 1.1 2.7 1.4 16.6 5.0 21.2 5.6 GNPDA1 "GNPDA, GNPI, GPI, HLN, KIAA0060" ENSG00000113552 "Glucosamine-6-phosphate deaminase 1" P46926 5 141991749-142013041 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 107.2;Proximal tubular cells: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 970000 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (6.79e-2)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (8.89e-3)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (9.66e-2)" "unprognostic (2.05e-3)" 15.6 28.2 13.9 10.0 19.1 4.3 18.7 12.6 22.5 16.5 13.7 13.2 11.7 18.0 24.8 34.0 10.7 11.9 13.7 10.6 12.3 16.1 46.2 10.2 11.0 21.8 14.1 16.5 20.7 7.7 15.1 19.9 18.9 13.4 17.8 14.0 17.1 10.6 18.9 16.5 9.0 18.8 18.4 10.9 18.2 9.5 16.3 10.8 12.4 18.2 9.2 11.8 23.6 11.2 7.9 20.6 5.0 22.7 5.6 32.7 14.7 9.5 14.0 5.5 27.0 18.8 12.7 12.8 7.6 18.3 20.2 23.0 20.9 11.4 0.0 17.4 5.4 90.8 10.1 25.4 22.6 17.9 7.3 10.9 7.0 8.2 14.9 33.4 19.4 9.3 15.2 13.4 12.8 34.4 15.1 21.1 18.7 8.3 25.9 21.6 6.0 14.7 2.2 20.5 14.4 28.3 5.7 17.8 21.3 19.4 26.5 4.8 12.7 15.1 15.7 28.8 16.8 12.8 6.1 10.0 11.8 8.0 18.1 10.7 14.5 27.8 10.7 17.3 6.6 10.3 0.0 19.4 2.6 15.7 22.7 32.7 7.9 12.8 14.4 20.6 3.7 15.5 16.5 5.0 5.6 20.4 11.6 10.6 14.7 13.9 19.1 12.6 22.5 12.3 16.1 14.1 16.5 13.4 10.8 8.9 9.3 7.5 31.0 5.4 9.7 10.9 15.3 8.1 20.5 17.4 7.9 22.9 29.9 25.3 0.9 13.0 9.9 0.0 12.2 39.3 11.5 18.6 11.5 5.9 107.2 6.4 14.5 17.2 52.5 2.5 18.4 36.7 13.5 23.4 6.6 35.2 18.7 6.0 25.1 73.4 6.3 0.0 8.1 5.1 16.8 6.5 24.8 17.0 8.3 32.4 GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726595 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 710000 Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (3.29e-1)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (9.75e-3)" "unprognostic (1.03e-1)" "unprognostic (1.28e-3)" "unprognostic (4.18e-2)" "unprognostic (6.86e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" 12.3 13.7 14.8 11.2 21.5 7.3 14.9 47.5 24.5 15.2 12.3 7.3 8.7 8.0 17.5 15.3 11.2 13.3 10.8 17.8 14.5 13.9 14.3 4.3 10.0 11.7 13.7 17.6 24.2 8.1 13.0 29.9 6.6 16.5 15.7 8.5 11.5 9.8 16.2 10.9 10.2 8.7 16.6 12.7 11.4 9.9 11.1 11.3 10.0 18.9 8.4 10.2 13.5 11.0 11.6 3.3 5.8 4.1 8.4 11.4 4.4 9.0 6.3 6.8 5.7 10.7 14.9 2.2 16.1 17.5 10.4 9.7 3.2 11.2 7.9 9.4 13.8 17.9 3.1 6.3 15.0 11.7 10.5 7.1 11.2 10.3 5.6 11.9 11.7 10.5 17.4 10.6 10.6 8.0 13.4 15.4 10.3 6.7 10.4 19.5 0.4 14.0 6.6 3.2 5.9 11.8 9.3 14.5 4.4 10.3 5.4 11.7 9.5 7.0 4.1 15.2 3.5 8.8 7.0 15.8 14.2 13.3 22.9 18.3 13.6 21.4 11.3 23.3 8.4 12.6 5.8 2.3 4.5 9.7 3.3 11.3 11.6 9.1 9.0 3.3 10.4 11.4 10.9 1.1 8.4 4.1 2.6 9.6 4.4 14.8 21.5 47.5 24.5 14.5 13.9 13.7 17.6 16.5 11.3 8.9 2.9 11.8 7.4 11.1 14.3 11.7 0.0 4.0 6.8 14.0 7.9 0.9 13.3 10.5 24.9 11.4 1.7 23.3 13.1 1.0 15.9 4.1 15.1 1.6 4.3 12.7 6.4 11.1 1.9 2.4 15.0 3.5 8.5 3.6 4.2 18.1 10.0 3.5 22.3 11.6 16.3 12.9 14.4 16.2 27.2 9.4 0.5 16.0 4.2 4.1 GNS ENSG00000135677 "Glucosamine (N-acetyl)-6-sulfatase" P15586 12 64713445-64759447 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Kupffer cells: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "non-classical monocyte: 50.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013695, CAB026011, HPA048508" Enhanced "Intracellular and membrane" NA NA 940000 "CAB026011: , HPA013695: AB_1849741, HPA048508: AB_2680423" "unprognostic (8.07e-2)" "unprognostic (2.39e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (9.33e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.04e-2)" "unprognostic (3.30e-2)" "unprognostic (3.28e-3)" "unprognostic (1.42e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-1)" "unprognostic (3.04e-1)" 57.0 96.7 9.0 18.2 10.1 7.4 47.5 7.7 11.6 22.6 19.1 15.4 17.7 11.5 27.1 27.4 14.3 18.7 21.9 33.0 9.0 10.7 48.9 36.7 26.6 48.8 9.6 8.7 32.7 16.0 32.2 16.6 43.5 15.5 18.6 12.8 38.2 17.9 17.1 18.2 13.5 21.6 23.6 10.8 33.6 16.5 19.3 8.4 9.1 31.4 10.4 11.7 23.9 18.2 3.0 18.2 12.9 50.0 3.9 7.0 19.0 7.8 12.1 10.0 16.4 50.3 30.3 21.3 18.2 42.5 21.7 24.0 11.1 10.7 3.3 23.8 23.2 25.6 6.5 9.9 10.4 24.6 9.9 7.2 7.9 9.9 7.1 22.9 5.9 70.9 29.0 12.9 22.1 10.1 68.8 40.0 4.6 5.5 23.8 31.7 6.3 1.4 3.4 3.9 19.9 10.3 4.6 15.6 10.3 18.9 23.1 6.8 7.3 23.7 11.5 16.5 13.8 20.6 7.9 36.9 21.4 11.3 20.7 10.6 22.6 26.9 2.9 30.8 11.5 14.5 8.8 30.3 5.9 7.0 37.0 5.2 3.0 3.8 5.3 18.2 2.4 4.0 4.0 12.9 3.9 50.0 4.3 2.8 19.0 9.0 10.1 7.7 11.6 9.0 10.7 9.6 8.7 15.5 8.4 44.7 34.3 16.7 7.2 14.7 9.2 56.5 25.5 21.4 18.2 97.7 17.7 15.9 1.7 27.2 23.8 39.4 30.9 0.0 12.9 14.7 22.9 22.9 46.2 54.2 72.6 15.9 40.3 68.7 167.4 19.5 32.2 65.5 15.1 24.4 18.5 23.6 21.5 16.4 35.0 61.7 6.0 6.5 18.9 10.9 7.8 11.3 24.4 10.1 15.8 16.1 GPCPD1 "GDE5, GDPD6, KIAA1434" ENSG00000125772 "Glycerophosphocholine phosphodiesterase 1" Q9NPB8 20 5544404-5611026 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042987 Approved Nucleoplasm NA NA Nucleoplasm "HPA042987: AB_2678254" "unprognostic (2.25e-2)" "unprognostic (2.45e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.30e-4)" "unprognostic (2.93e-2)" "unprognostic (8.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-2)" "unprognostic (3.76e-2)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.56e-1)" "unprognostic (1.22e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-2)" 12.9 12.9 10.6 21.8 17.6 56.7 12.7 29.6 28.2 12.2 8.8 9.1 36.7 7.4 12.5 10.5 10.6 12.6 13.2 12.6 12.2 10.1 8.1 8.1 43.6 30.6 13.1 8.9 18.1 8.9 4.5 10.3 13.4 19.4 9.6 10.6 11.0 34.2 31.2 31.8 9.1 15.1 21.5 14.6 24.9 8.8 8.1 4.0 12.1 13.4 17.0 17.5 13.7 9.8 4.2 4.5 16.2 7.1 3.6 4.6 3.4 3.8 7.3 5.0 4.0 3.3 3.9 5.7 6.1 4.9 3.5 2.4 3.8 3.0 8.6 1.1 3.4 3.2 1.3 6.2 12.1 3.4 1.8 2.0 11.8 0.8 4.4 16.0 7.2 5.4 8.3 15.8 2.1 26.1 3.6 3.7 5.4 6.7 4.5 3.2 2.1 6.5 3.9 2.7 6.8 4.2 4.7 6.0 3.1 4.8 3.2 1.9 2.5 2.7 11.9 5.7 5.2 2.8 20.3 4.1 3.0 2.2 8.2 3.9 4.3 7.4 9.2 0.9 8.9 3.3 2.6 7.1 9.0 4.0 5.5 3.1 4.2 3.0 3.3 4.5 3.8 4.6 3.1 16.2 3.6 5.5 2.0 2.4 3.4 10.6 17.6 29.6 28.2 12.2 10.1 13.1 8.9 19.4 4.0 20.8 56.2 34.4 13.7 14.7 16.4 35.1 15.3 13.4 31.8 21.0 5.9 24.1 3.3 10.4 145.3 24.3 12.0 70.0 7.9 13.9 20.4 21.1 42.7 15.3 42.6 11.1 18.9 20.9 80.0 39.0 5.2 52.4 10.1 10.0 20.3 9.1 6.0 8.6 3.2 6.3 19.4 6.5 35.6 39.0 9.5 24.0 40.7 32.0 10.4 44.4 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 61.6" "Cell type enhanced" "Detected in many" 15 "Bipolar cells: 17.5;Cone photoreceptor cells: 64.8;Hepatocytes: 55.7" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Region enriched" "Detected in many" 4 "cerebellum: 8.5" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 10.5;U-698: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" NA NA 103000000000 3700000000 "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 2.2 0.4 0.8 0.6 1.2 0.3 0.6 8.5 1.8 0.6 0.6 0.6 0.6 0.1 0.8 0.6 0.6 0.4 0.6 0.6 0.6 1.9 0.6 61.6 0.6 0.6 0.7 0.6 0.7 0.6 1.5 1.3 0.6 0.6 1.0 0.1 0.6 0.6 3.3 0.7 4.8 0.6 0.8 0.6 0.6 0.3 0.8 0.6 6.6 1.6 0.6 0.7 1.0 1.0 1.1 1.6 0.4 0.2 0.1 1.8 0.0 0.7 1.3 1.2 1.9 0.0 0.1 3.0 0.1 0.3 0.4 0.3 5.4 0.1 10.5 1.2 0.2 0.3 0.0 1.7 0.3 0.2 1.3 3.5 1.5 1.4 4.4 0.0 1.8 0.2 0.1 0.2 0.1 0.0 1.2 0.0 2.6 0.7 0.5 0.3 0.7 1.0 0.6 4.0 0.7 0.5 2.0 0.3 0.1 0.4 5.2 3.3 3.5 1.1 0.1 0.5 0.9 0.5 0.5 0.1 1.3 1.3 0.1 1.4 3.1 4.8 10.7 0.2 0.5 0.5 0.4 0.2 0.1 0.4 0.1 1.4 0.6 0.3 0.2 0.0 1.1 0.3 1.8 0.4 0.1 0.1 1.6 0.2 0.0 0.8 1.2 8.5 1.8 0.6 1.9 0.7 0.6 0.6 0.6 0.0 3.0 0.0 0.4 0.0 17.5 10.1 0.0 1.4 2.3 1.8 64.8 0.2 0.0 0.3 3.0 1.0 0.0 0.0 0.3 0.3 0.3 0.3 0.0 55.7 0.1 14.3 1.7 0.6 1.3 2.3 2.8 0.0 0.0 0.0 0.3 4.3 0.1 0.0 3.2 0.3 10.5 0.0 0.5 0.5 5.3 0.5 0.0 0.0 0.4 2.2 GTF2F2 "BTF4, RAP30, TFIIF" ENSG00000188342 "General transcription factor IIF subunit 2" P13984 13 45120515-45284909 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006912 Supported Supported Nucleoplasm,Microtubules NA NA Nucleoplasm Microtubules "HPA006912: AB_1080256" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.65e-5)" "unprognostic (3.67e-2)" "unprognostic (3.17e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-3)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.53e-3)" "unprognostic (3.94e-2)" "unprognostic (6.44e-3)" 15.1 24.7 23.5 21.1 23.6 22.5 20.9 12.0 21.0 16.3 21.8 14.8 18.5 14.9 16.8 23.4 21.8 12.0 15.9 27.5 21.4 21.1 18.3 16.0 15.1 17.5 22.9 19.0 17.3 14.6 16.5 27.5 23.9 18.2 16.7 21.2 18.2 20.8 20.2 32.0 31.5 12.9 28.2 19.5 17.8 15.2 22.2 24.2 22.6 19.2 27.7 19.9 20.5 19.0 15.4 16.3 24.9 15.3 16.1 12.9 8.5 15.5 5.8 11.1 8.2 6.8 10.1 9.2 17.2 11.3 17.5 17.2 9.8 24.5 15.7 9.7 12.5 17.1 17.4 16.6 13.8 25.7 11.8 14.4 18.5 7.8 12.8 10.9 20.5 10.6 8.4 21.2 13.1 22.2 19.9 11.2 12.3 13.1 5.9 47.1 8.7 15.0 23.6 13.2 25.1 14.4 14.1 8.4 9.0 38.2 5.5 5.9 9.9 8.7 8.6 14.3 10.9 7.0 16.8 8.8 14.8 12.6 11.7 29.3 3.8 5.2 15.7 17.2 13.2 15.4 12.0 14.2 24.9 9.7 14.1 11.5 15.3 11.3 11.5 16.3 15.4 12.9 12.6 19.8 16.1 15.3 12.7 12.3 8.5 23.5 23.6 12.0 21.0 21.4 21.1 22.9 19.0 18.2 24.2 38.7 28.0 38.3 76.6 66.6 18.2 68.7 10.2 33.5 33.0 10.4 3.9 28.1 41.4 45.9 94.3 28.4 21.3 23.3 28.9 40.9 31.4 27.4 39.2 17.8 42.4 7.9 27.1 12.3 27.1 62.8 22.5 37.1 72.6 31.5 24.5 34.7 38.8 25.9 29.7 30.5 18.5 6.5 27.8 59.2 80.1 63.6 28.3 27.1 37.6 64.0 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982314 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 56.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 48000 Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 23.5 12.0 3.7 7.9 5.5 20.7 25.4 5.7 4.4 10.4 14.6 7.7 22.0 10.0 10.4 12.2 9.3 7.6 11.1 8.0 3.7 2.9 11.8 50.4 15.3 12.3 6.3 3.1 8.6 17.1 9.0 7.3 30.0 4.5 12.1 11.4 9.9 17.2 11.8 5.9 10.0 16.1 8.3 3.9 17.5 11.0 7.9 5.8 14.7 17.7 5.9 13.0 9.2 7.4 9.7 27.7 22.1 36.0 15.2 11.5 15.8 17.0 6.6 6.5 14.5 22.1 13.2 9.4 5.4 15.1 11.9 11.0 9.5 17.6 7.8 8.5 6.9 6.2 6.9 4.2 6.5 7.1 7.3 8.5 10.6 10.0 6.4 10.8 22.7 17.7 9.1 7.0 6.9 9.0 14.2 10.4 4.5 16.1 56.5 7.7 12.4 8.3 24.4 4.3 26.0 5.5 8.6 15.0 44.2 7.5 10.3 9.5 8.4 14.5 33.9 18.9 7.6 18.9 22.6 7.3 14.6 13.2 5.5 13.5 32.1 38.5 13.1 10.9 30.2 17.7 7.4 28.1 22.1 11.5 36.0 10.3 9.7 9.0 10.2 27.7 7.8 6.2 7.3 4.5 15.2 30.0 11.3 11.3 15.8 3.7 5.5 5.7 4.4 3.7 2.9 6.3 3.1 4.5 5.8 47.6 56.2 18.6 26.4 16.0 13.7 8.3 25.5 48.2 37.5 27.9 7.9 72.3 5.0 32.4 47.6 31.3 41.1 23.3 26.7 48.8 48.3 25.5 35.8 64.7 114.3 15.9 41.2 39.9 74.2 36.8 40.0 72.1 37.1 43.3 42.3 27.3 25.9 48.9 26.9 19.2 17.7 25.8 22.6 41.3 28.8 12.9 56.0 34.6 40.6 25.3 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102648-55110252 "Enzymes, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 92.3;intestine: 31.0;lymphoid tissue: 40.9" "Cell type enriched" "Detected in many" 28 "T-cells: 796.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 13 "gdT-cell: 92.3;MAIT T-cell: 90.8;memory CD4 T-cell: 25.4;memory CD8 T-cell: 89.3;naive CD8 T-cell: 50.5;NK-cell: 61.9" "Group enriched" "Detected in many" 38 "NK-cells: 61.9;T-cells: 92.3" "Cell line enhanced" "Detected in some" "HL-60: 8.4;JURKAT: 6.3;REH: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 4.3 1.8 1.1 16.3 1.2 10.0 2.5 0.7 0.8 3.9 12.5 0.9 1.3 10.3 5.2 2.9 2.9 2.9 9.6 4.5 1.1 1.1 4.6 5.2 11.8 20.3 1.7 0.9 3.0 5.8 0.0 1.9 5.8 1.5 3.4 6.3 4.5 5.1 1.3 2.6 1.2 31.0 2.5 2.6 40.9 3.9 1.1 0.6 1.9 3.1 4.2 11.1 6.6 2.9 0.2 0.2 2.0 0.3 61.9 92.3 52.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 1.9 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 92.3 0.2 90.8 0.2 25.4 89.3 0.2 0.1 5.2 50.5 2.0 61.9 0.3 0.2 2.9 52.0 1.1 1.2 0.7 0.8 1.1 1.1 1.7 0.9 1.5 0.6 3.0 28.1 9.2 0.0 0.3 0.0 0.7 2.5 5.3 5.7 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.3 0.0 0.0 0.1 0.8 0.1 7.0 2.4 0.2 0.0 0.0 12.3 16.8 0.0 0.0 1.3 3.3 0.0 0.6 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.4 0.0 0.0 1.3 0.6 796.9 0.5 0.0 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "blood: 298.5" "Cell type enriched" "Detected in many" 4 "T-cells: 243.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 298.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 298.5" "Cell line enriched" "Detected in some" 5 "HMC-1: 21.2" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 6.4 0.7 0.8 8.0 1.1 26.4 3.2 0.7 0.7 1.6 3.0 0.5 1.3 0.8 3.9 1.5 4.0 1.0 3.1 4.8 0.7 2.4 2.1 5.7 21.7 16.7 1.1 0.0 1.4 0.7 0.0 1.0 7.5 0.8 2.6 0.9 4.0 2.7 2.3 3.5 0.6 2.9 1.8 1.5 33.0 3.5 0.9 0.4 6.1 4.4 5.3 16.8 6.0 1.5 0.2 298.5 2.0 0.2 19.9 60.5 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.9 0.3 0.1 0.2 60.5 0.1 0.7 0.2 4.6 28.4 0.2 0.1 1.4 28.7 2.0 19.9 0.2 298.5 0.1 53.6 0.8 1.1 0.7 0.7 0.7 2.4 1.1 0.0 0.8 0.4 6.0 57.5 21.4 0.2 2.5 0.0 0.4 0.0 8.1 13.6 0.0 0.0 0.1 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.2 16.3 1.1 0.2 0.0 0.0 3.1 2.1 0.0 0.0 5.5 40.5 0.0 0.0 0.0 0.1 0.2 0.0 2.1 0.0 0.0 0.5 0.0 0.0 3.6 0.2 243.7 0.2 0.1 H6PD GDH ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234775-9271337 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 116.9" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 33.5;HSkMC: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 91000000 Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" 18.3 16.1 4.1 10.7 5.5 4.8 12.2 4.1 6.3 16.6 11.9 10.5 8.2 6.3 22.0 18.0 11.1 15.6 11.9 11.9 3.7 3.0 7.0 116.9 12.2 11.1 6.8 2.6 38.3 10.6 8.0 8.7 14.9 6.0 11.6 5.3 11.8 29.8 8.1 24.7 20.7 10.4 10.2 6.6 10.7 9.9 12.4 5.5 16.2 12.6 12.9 14.1 12.2 10.1 4.5 3.7 4.1 6.3 3.1 4.7 3.0 3.9 3.2 2.8 10.5 29.2 33.5 2.7 3.9 9.8 2.9 4.6 0.6 8.1 4.3 4.6 6.1 3.7 4.1 0.7 1.9 4.3 12.9 0.9 0.0 1.0 2.6 16.3 1.4 1.7 32.9 3.8 7.0 4.6 6.5 13.4 2.4 1.1 7.5 5.7 2.3 1.5 3.2 1.5 2.9 1.9 0.5 0.3 3.6 3.8 1.6 0.9 5.0 5.2 4.1 4.9 2.0 3.1 7.0 13.3 10.1 1.7 2.5 1.1 10.0 2.9 1.0 16.9 6.3 6.4 3.5 6.2 0.9 4.7 6.3 3.7 3.5 3.5 4.1 2.8 4.5 3.4 3.2 4.1 3.1 5.8 3.7 2.8 3.0 4.1 5.5 4.1 6.3 3.7 3.0 6.8 2.6 6.0 5.5 23.8 29.3 11.2 11.1 12.7 18.1 13.0 58.6 10.7 12.5 19.2 25.5 9.0 0.0 15.8 0.8 14.7 15.1 0.0 18.5 6.5 24.0 16.2 3.5 132.8 11.5 15.9 7.5 17.8 18.0 1.5 44.5 10.3 11.8 64.9 15.2 11.2 20.1 17.5 34.6 8.2 11.5 0.0 9.2 4.7 4.6 11.2 4.9 13.8 24.1 11.4 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827194 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.4" "Cell type enhanced" "Detected in all" 7 "Proximal tubular cells: 487.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 3000000 "HPA043041: AB_2678284, HPA061143: AB_2684439" "unprognostic (3.11e-1)" "prognostic favorable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favorable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favorable (5.19e-4)" 14.8 36.9 24.9 7.8 26.7 26.2 16.4 26.8 35.3 9.7 12.9 13.6 19.6 17.6 6.8 13.0 11.7 11.8 9.9 50.9 28.0 24.5 38.8 91.4 14.5 8.5 23.2 24.5 6.3 24.6 17.1 19.7 9.2 18.5 12.4 9.5 11.9 12.5 16.2 67.1 11.0 17.1 11.7 20.7 10.1 13.1 33.8 13.7 7.4 14.1 18.3 7.2 9.7 18.2 13.7 28.9 27.7 36.5 10.9 18.3 12.5 11.5 17.5 15.8 17.9 13.9 5.5 14.3 14.5 13.5 22.4 18.1 9.0 10.1 2.4 29.8 12.4 15.4 12.6 15.0 14.5 6.7 23.9 24.1 4.4 17.9 25.6 20.0 5.8 24.3 6.7 31.2 11.2 7.7 19.8 19.2 30.4 5.8 21.7 7.0 19.0 15.0 12.6 6.0 11.9 16.2 12.7 10.0 27.2 28.7 5.2 21.3 18.4 15.9 20.4 31.1 12.5 15.0 19.5 14.6 6.8 8.5 14.2 16.6 24.6 23.2 7.1 11.6 5.4 10.9 14.4 15.3 27.7 12.6 25.8 9.2 13.7 16.2 12.9 13.7 12.4 15.8 13.2 13.5 10.9 36.5 28.9 18.3 12.5 24.9 26.7 26.8 35.3 28.0 24.5 23.2 24.5 18.5 13.7 8.9 32.9 46.9 39.2 21.2 110.6 73.4 58.6 26.8 11.4 43.6 60.9 45.4 134.3 38.1 141.4 30.0 81.5 280.4 33.8 33.2 26.9 51.0 30.0 169.8 67.1 130.3 38.1 41.7 39.3 41.7 43.4 47.0 52.3 57.7 36.1 79.2 45.7 70.2 51.6 487.6 102.8 71.1 36.8 224.6 49.5 39.9 57.4 54.2 35.0 42.0 HDAC1 "GON-10, HD1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292086-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "CAB005017: AB_2248344, CAB068191: AB_2665664, HPA029693: AB_10601659" "unprognostic (2.51e-2)" "unprognostic (9.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.47e-2)" "unprognostic (7.06e-2)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (6.86e-2)" "unprognostic (3.78e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" 13.8 22.8 12.8 33.5 14.8 15.0 21.1 5.1 13.0 21.9 35.7 16.0 34.8 22.2 24.6 17.5 40.6 21.0 43.8 12.4 12.5 8.5 21.1 21.5 17.2 33.3 14.7 8.6 27.7 20.5 17.2 27.1 24.4 12.2 25.2 33.9 18.0 27.8 31.3 6.6 16.9 32.7 22.1 13.3 32.6 27.8 20.0 16.7 59.4 36.8 21.2 51.1 26.0 25.1 47.7 32.1 59.8 44.6 42.4 49.2 54.7 29.4 18.0 11.6 23.0 6.8 8.1 24.1 20.9 23.4 28.0 25.9 32.9 53.1 45.4 38.8 23.0 28.5 34.4 35.5 28.4 31.1 42.4 35.3 31.3 21.6 25.2 16.0 55.4 45.4 14.6 15.6 21.7 14.4 22.0 21.2 59.5 41.0 18.1 12.3 22.4 63.1 31.2 26.8 35.2 46.1 43.6 27.5 20.2 30.3 42.6 9.1 11.5 34.8 23.5 43.8 47.7 27.7 43.1 24.5 18.7 21.9 5.7 50.8 11.0 23.7 62.3 15.4 46.0 24.2 37.0 27.7 59.8 43.2 35.5 35.4 47.7 42.4 46.1 32.1 44.3 49.2 45.7 19.9 42.4 44.6 20.1 42.5 54.7 12.8 14.8 5.1 13.0 12.5 8.5 14.7 8.6 12.2 16.7 23.8 38.4 50.1 48.1 22.0 15.5 18.2 56.0 80.3 48.9 64.6 15.7 81.3 81.2 57.2 10.0 40.9 97.1 0.0 65.1 93.0 21.5 29.1 29.0 28.2 38.0 11.1 82.9 63.8 40.8 5.9 38.0 31.0 27.0 42.3 101.3 32.1 65.7 108.7 41.8 25.9 13.9 58.2 37.7 45.1 76.2 22.2 78.1 50.7 115.8 49.8 HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB045977 Supported NA NA "CAB045977: AB_11124034" "unprognostic (1.53e-1)" "prognostic favorable (4.46e-4)" "unprognostic (1.43e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (6.15e-3)" "unprognostic (5.48e-2)" "unprognostic (3.28e-1)" "unprognostic (2.56e-2)" "prognostic favorable (9.25e-4)" "unprognostic (4.93e-2)" "prognostic unfavorable (4.74e-11)" "unprognostic (2.21e-2)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" 8.9 9.3 10.1 14.7 10.3 16.9 6.8 10.9 8.8 8.6 13.9 4.7 14.6 12.9 7.7 13.5 10.2 7.9 13.1 4.0 8.4 6.1 11.4 15.1 8.2 12.5 4.9 8.8 7.8 15.0 6.4 13.2 7.0 6.1 10.2 3.7 8.8 18.6 12.9 9.2 12.1 14.2 7.1 4.4 17.1 14.2 2.4 4.7 16.1 9.3 7.6 19.2 8.2 7.7 1.1 3.1 5.4 4.2 1.1 1.9 2.5 4.2 2.4 0.6 3.5 3.0 2.4 7.8 2.8 2.4 1.6 0.9 4.4 4.6 2.7 4.0 2.1 1.5 7.0 1.5 4.2 0.3 3.5 3.9 5.9 6.2 7.3 5.3 6.9 19.3 5.0 3.1 1.5 0.9 3.2 3.0 5.6 4.1 4.2 1.4 13.0 3.8 17.3 1.4 4.5 5.2 9.2 2.3 17.0 2.5 7.1 1.9 4.6 2.9 1.0 4.9 0.8 8.0 11.2 4.7 2.8 4.0 4.7 1.7 5.2 1.8 2.3 4.5 4.4 2.1 0.8 4.0 5.4 1.9 4.2 1.6 1.0 0.9 1.2 3.1 1.1 0.8 1.0 2.0 1.1 2.3 2.7 1.6 2.5 10.1 10.3 10.9 8.8 8.4 6.1 4.9 8.8 6.1 4.7 0.0 4.3 9.8 4.4 7.7 5.4 0.6 7.6 4.0 2.3 14.0 15.7 9.3 6.6 5.7 1.8 5.6 25.6 0.0 3.4 13.2 8.5 3.2 4.7 6.7 18.7 0.0 20.1 9.2 21.1 6.3 10.3 10.8 8.5 17.2 14.6 2.6 5.7 17.0 7.4 13.3 6.8 0.0 3.7 0.9 2.3 8.3 8.6 30.6 14.4 3.1 HDAC11 ENSG00000163517 "Histone deacetylase 11" Q96DB2 3 13479724-13506424 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Early spermatids: 300.6;Late spermatids: 525.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 27.9;T-47d: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (5.22e-2)" "unprognostic (3.58e-2)" "unprognostic (1.83e-1)" "unprognostic (5.69e-3)" "unprognostic (1.76e-1)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (4.50e-2)" "unprognostic (5.67e-3)" "unprognostic (1.78e-2)" "unprognostic (9.87e-2)" "unprognostic (3.94e-1)" "prognostic favorable (7.88e-10)" "unprognostic (3.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.46e-1)" "unprognostic (1.39e-3)" 4.8 7.6 24.6 3.2 31.7 0.7 5.8 7.6 30.6 8.8 7.1 29.2 3.8 8.9 6.5 5.1 9.5 10.1 6.5 19.6 24.4 19.0 9.9 2.1 6.4 3.0 25.4 20.7 12.5 18.8 10.4 7.7 3.4 16.5 8.2 5.1 6.6 12.8 9.7 35.1 13.2 9.6 5.4 19.9 3.0 4.9 24.0 20.3 1.5 9.9 4.9 3.7 4.4 6.6 1.4 2.3 7.5 3.3 11.4 4.5 2.3 6.9 4.5 4.8 3.9 7.1 6.2 3.6 4.6 3.2 4.6 3.1 2.2 5.8 0.5 5.5 6.4 7.3 5.3 2.8 8.3 3.0 3.0 2.6 1.3 1.9 6.3 8.0 0.1 2.5 5.2 15.6 5.1 3.9 8.6 3.3 4.3 2.7 1.3 4.3 7.0 0.8 0.9 1.3 4.5 12.0 0.9 6.9 2.0 9.6 5.1 0.8 3.6 6.6 27.9 13.2 4.1 24.6 1.6 3.1 3.9 7.9 7.7 2.7 0.9 2.5 0.1 1.2 1.0 2.2 0.2 3.3 7.5 4.5 1.8 3.1 1.4 4.1 3.5 2.3 0.6 4.1 2.7 1.4 11.4 0.7 2.3 3.3 2.3 24.6 31.7 7.6 23.0 24.4 19.0 25.4 20.7 16.5 20.3 8.9 5.3 0.0 7.4 10.2 8.7 71.4 10.2 9.4 3.4 10.4 0.0 15.7 16.6 11.3 300.6 4.5 28.8 0.0 10.0 2.1 7.6 4.5 1.1 2.6 5.2 9.5 8.5 7.4 4.3 525.1 15.0 3.1 8.5 6.4 14.8 17.7 10.6 16.9 14.5 14.2 5.8 0.0 6.9 10.2 6.0 9.3 4.8 4.3 18.5 5.0 HDAC2 "RPD3, YAF1" ENSG00000196591 "Histone deacetylase 2" Q92769 6 113933028-114011308 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005054, HPA011727" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB005054: AB_562295, HPA011727: AB_1850540" "prognostic unfavorable (7.07e-4)" "unprognostic (1.44e-1)" "unprognostic (2.67e-1)" "unprognostic (2.56e-2)" "unprognostic (2.61e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (5.39e-10)" "unprognostic (2.03e-1)" "unprognostic (2.63e-2)" "unprognostic (9.00e-2)" "unprognostic (2.01e-1)" "unprognostic (3.92e-1)" "unprognostic (1.84e-2)" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (9.80e-2)" "unprognostic (3.51e-1)" 25.8 33.8 25.8 30.1 31.3 34.9 58.7 32.8 36.5 32.1 30.7 25.6 32.2 22.0 38.7 36.7 36.3 32.7 23.3 27.6 26.5 26.9 31.6 22.2 29.9 41.5 29.6 26.5 39.2 31.5 31.7 45.1 38.1 27.9 32.1 36.1 17.5 29.3 39.0 33.9 30.8 26.1 36.1 31.1 30.7 29.9 47.4 27.4 64.0 35.1 31.3 32.5 33.1 47.3 27.0 35.7 28.2 32.6 26.3 32.6 24.3 24.6 17.0 79.6 45.7 20.5 23.5 33.3 29.5 24.1 34.8 41.7 45.1 18.2 20.4 24.6 26.5 35.8 19.4 54.0 29.8 58.7 29.0 37.3 49.1 22.1 26.0 27.4 49.8 22.2 18.9 20.1 37.0 34.8 34.1 40.5 36.1 63.1 20.7 57.6 20.7 44.6 45.1 45.0 26.4 23.5 30.3 39.7 18.7 35.9 29.8 53.3 45.2 23.3 22.0 24.5 50.0 16.0 58.1 32.7 22.2 25.5 23.2 48.8 16.5 21.7 48.8 18.8 48.0 37.6 23.1 27.6 28.2 21.1 26.6 28.1 27.0 25.9 22.7 35.7 22.3 32.6 29.7 16.3 26.3 32.6 30.9 24.5 24.3 25.8 31.3 32.8 36.5 26.5 26.9 29.6 26.5 27.9 27.4 53.6 49.8 31.2 71.8 170.6 26.7 56.1 33.1 81.7 79.6 50.6 3.9 139.9 36.5 140.8 72.3 70.5 33.4 140.2 91.3 114.1 97.6 61.7 53.2 30.8 91.5 14.3 96.4 47.9 63.7 84.2 76.8 67.2 79.2 128.0 68.7 30.1 115.2 49.1 63.3 52.8 23.5 38.8 84.5 123.0 166.8 168.8 173.7 50.7 90.3 79.6 HDAC3 "HD3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636870 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: AB_2681708" "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favorable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" 15.9 28.8 19.6 12.2 17.6 18.1 18.6 22.6 20.8 15.6 14.1 11.2 13.1 10.6 17.3 17.6 22.8 16.3 14.0 16.8 18.0 8.9 14.5 23.3 24.4 36.4 13.4 14.2 17.3 24.7 20.9 17.3 14.3 18.8 13.6 14.4 13.6 17.5 13.7 24.5 26.7 15.2 17.2 10.8 20.1 15.5 11.9 12.6 18.5 14.4 9.6 23.7 17.5 17.0 22.1 46.7 16.4 22.6 14.1 23.1 16.9 21.3 14.5 27.0 40.9 26.1 20.8 17.5 15.6 34.3 35.4 50.8 31.0 18.3 31.1 20.2 20.2 25.2 18.6 27.1 36.5 43.9 26.5 29.1 24.3 13.3 17.6 18.4 29.2 22.3 17.7 23.5 20.5 26.8 18.4 22.8 28.1 23.7 16.6 22.3 20.2 32.4 25.3 23.8 13.3 11.5 23.5 28.2 22.4 18.9 21.5 22.6 18.3 20.6 21.4 25.7 17.9 22.8 18.5 11.5 22.0 13.8 16.8 25.5 13.5 16.6 29.3 18.5 27.8 18.8 13.2 22.4 16.4 15.9 22.6 20.8 22.1 19.8 19.2 46.7 20.1 21.7 18.0 9.5 14.1 19.0 23.9 23.1 16.9 19.6 17.6 22.6 20.8 18.0 8.9 13.4 14.2 18.8 12.6 8.9 10.4 32.3 23.0 39.3 30.6 12.3 15.3 5.3 11.4 12.2 56.9 47.2 18.3 28.5 7.6 20.2 15.4 0.0 31.4 44.3 29.3 18.8 18.4 14.8 34.9 47.7 17.2 20.9 15.4 3.4 20.8 33.0 30.4 66.7 17.7 27.7 27.2 14.0 20.8 15.7 30.4 25.8 24.0 22.3 24.5 44.9 51.1 31.9 22.7 26.5 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 54.6" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 73.9;Late spermatids: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 10.5;classical monocyte: 7.4;neutrophil: 28.3" "Group enriched" "Detected in many" 8 "granulocytes: 28.3;monocytes: 7.4" "Cell line enhanced" "Detected in many" "JURKAT: 30.4;MOLT-4: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 7.9 6.8 6.1 6.8 5.2 17.1 4.6 6.4 12.3 11.3 21.4 4.6 4.3 2.5 10.2 6.4 8.8 9.0 24.6 5.2 5.0 6.0 3.2 3.1 4.2 4.3 6.1 5.4 8.5 5.8 4.9 8.3 2.5 5.2 7.5 4.8 8.3 3.7 7.3 54.6 6.9 6.5 15.8 4.2 5.4 7.0 8.1 4.3 6.5 4.8 13.2 5.6 10.2 4.6 0.5 1.7 28.3 7.4 2.1 1.2 0.4 3.8 3.8 4.9 5.9 2.8 4.7 5.8 4.0 2.7 3.2 3.1 1.7 7.0 1.8 1.6 3.4 4.6 3.8 3.4 1.6 1.6 10.6 1.8 2.8 4.7 5.6 3.7 4.3 2.6 3.2 4.1 5.9 4.7 1.6 3.4 30.4 4.0 4.1 1.5 4.7 28.1 5.9 3.8 4.8 2.0 7.3 9.2 2.8 3.7 4.9 3.9 6.9 5.6 2.5 9.8 2.9 1.3 11.9 5.4 3.7 0.3 6.4 5.4 2.9 2.7 3.5 5.4 6.0 7.4 10.5 7.4 1.1 0.9 2.4 1.1 0.5 0.9 0.8 0.8 0.5 0.5 1.0 28.3 2.1 1.0 1.7 1.2 0.4 6.1 5.2 6.4 7.5 5.0 6.0 6.1 5.4 5.2 4.3 3.0 9.0 3.7 2.2 7.0 11.5 10.1 7.6 0.0 3.4 10.4 2.0 1.2 0.0 2.4 73.9 5.8 4.5 0.0 1.8 1.5 8.0 5.0 2.3 5.8 2.9 15.9 5.8 13.5 22.7 47.3 10.9 5.5 5.0 0.0 5.5 10.1 1.7 0.0 11.7 1.2 7.1 0.0 5.6 2.2 2.1 8.4 1.1 8.7 5.7 2.2 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 111.9;Syncytiotrophoblasts: 182.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favorable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 15.6 17.6 24.9 7.9 15.8 13.2 18.1 35.9 25.8 16.5 8.8 19.6 9.5 8.4 15.0 11.9 20.1 16.9 11.3 24.4 22.1 24.2 8.6 6.3 13.6 8.8 24.7 22.1 24.5 16.1 28.2 17.5 23.0 19.3 13.6 5.5 11.7 14.2 11.9 42.6 34.0 9.7 12.4 20.5 13.8 9.3 10.3 18.1 7.6 15.0 9.8 8.2 14.9 20.4 7.6 9.4 17.9 13.6 3.5 4.9 5.0 3.6 2.4 6.5 1.5 12.7 9.8 23.6 9.8 24.4 4.9 8.0 5.2 3.9 5.7 3.9 23.2 7.3 2.9 7.6 4.2 2.1 8.8 12.4 11.1 7.8 12.0 5.4 3.6 15.7 13.9 7.2 5.6 7.0 8.4 4.0 4.6 8.2 11.6 28.3 2.8 5.9 10.9 7.1 2.8 5.6 22.9 18.2 14.7 0.5 1.6 17.0 8.9 2.8 12.0 13.3 10.1 17.1 21.0 2.2 12.3 7.9 2.8 4.9 19.2 16.0 6.8 7.1 4.5 5.8 7.1 7.3 7.7 4.9 11.6 3.5 6.6 3.9 4.9 9.4 7.6 4.1 3.5 17.9 3.5 13.6 8.3 3.5 5.0 24.9 15.8 35.9 25.8 22.1 24.2 24.7 22.1 19.3 18.1 11.9 13.6 10.4 30.2 26.0 84.0 21.0 12.7 5.3 7.9 19.2 111.9 12.7 18.3 13.6 17.9 18.3 11.2 0.0 7.5 47.4 24.1 34.1 11.6 9.0 19.6 77.9 44.2 20.3 12.1 8.7 44.8 13.6 13.5 9.0 13.7 17.3 12.1 15.8 41.1 6.4 58.6 64.7 41.8 2.3 33.8 28.7 182.4 17.5 11.2 18.5 HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported Nucleoplasm NA NA 39000 Nucleoplasm "CAB004236: AB_627708, HPA003714: AB_1850544, HPA026321: AB_1850546" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (2.42e-2)" "unprognostic (2.82e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-3)" "unprognostic (2.33e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "prognostic favorable (3.34e-4)" 14.6 13.7 23.4 12.8 29.8 19.0 14.4 34.2 30.1 12.7 14.1 24.4 14.9 16.9 16.0 14.7 13.1 15.7 11.7 11.9 21.7 24.8 32.8 43.3 15.1 13.9 27.2 22.4 18.7 15.5 26.7 24.4 15.1 27.0 12.3 15.9 15.1 12.2 15.3 18.2 11.3 16.1 15.0 20.9 15.3 14.2 24.7 22.4 19.0 15.7 9.5 14.0 11.7 12.1 5.7 9.7 6.3 12.4 4.0 5.8 5.0 15.1 12.9 25.3 9.6 10.2 9.3 17.1 7.2 6.2 14.0 13.8 12.4 13.0 14.6 7.0 8.2 17.9 10.8 15.3 7.7 12.1 13.6 9.7 20.0 15.4 12.7 9.6 9.2 31.0 13.5 12.6 10.9 13.2 12.5 11.6 18.5 21.9 16.2 8.8 5.3 13.0 14.4 9.4 6.9 12.3 11.2 27.2 15.0 8.0 6.6 13.0 12.8 14.6 4.4 8.7 34.3 18.3 8.6 9.4 10.9 14.1 14.9 6.9 14.9 14.8 10.6 11.1 11.9 10.8 0.0 5.8 6.3 5.8 9.7 4.1 4.3 4.0 4.2 8.6 5.7 3.9 3.7 2.9 4.0 12.4 9.7 4.4 5.0 23.4 29.8 34.2 30.1 21.7 24.8 27.2 22.4 27.0 22.4 17.9 30.9 11.7 10.4 6.6 37.4 9.5 12.7 9.4 20.5 17.4 47.1 9.6 16.6 6.3 37.4 7.7 17.6 0.0 6.4 10.4 8.4 7.6 5.8 45.7 9.7 38.1 13.8 11.6 10.0 14.2 13.0 9.2 5.0 15.4 11.6 26.8 6.8 11.5 10.6 39.4 33.8 12.9 8.0 31.5 13.0 5.1 8.1 6.7 13.6 6.4 HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" 4 "Ito cells: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol NA NA Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.65e-4)" 26.0 21.6 8.2 22.7 10.8 17.3 24.4 8.4 10.7 28.2 20.7 8.7 15.4 8.0 27.9 21.5 19.2 25.2 22.1 16.5 10.3 4.3 17.7 5.1 27.6 21.1 8.2 8.0 25.4 8.9 23.7 11.5 17.5 10.0 20.1 4.1 17.6 16.3 18.9 12.5 19.7 13.9 24.9 10.3 23.1 14.9 9.5 11.5 85.8 20.9 12.9 21.0 24.8 25.0 1.4 0.6 10.5 1.9 1.7 1.5 1.8 14.2 9.7 10.1 16.5 7.9 22.1 9.1 14.0 10.9 10.2 6.7 12.9 13.5 28.6 46.8 12.7 5.0 13.2 2.3 10.9 3.7 13.4 4.8 9.8 9.5 3.0 8.6 3.0 0.4 14.4 3.8 10.1 5.5 18.4 21.0 16.4 10.3 11.7 6.4 6.2 28.1 7.5 14.1 3.1 10.8 21.7 5.4 10.3 4.3 9.3 2.9 6.9 10.7 5.0 5.1 6.8 4.7 4.1 23.8 20.9 22.7 17.0 9.9 26.5 19.2 22.7 8.6 14.5 6.8 0.0 1.9 0.0 1.5 0.8 1.5 1.4 1.3 1.1 0.6 1.1 1.5 1.0 10.5 1.7 0.7 0.5 0.6 1.8 8.2 10.8 8.4 10.7 10.3 4.3 8.2 8.0 10.0 11.5 38.7 36.7 31.8 21.0 12.2 18.0 11.5 30.6 5.3 22.7 34.9 0.0 3.9 1.7 29.4 13.4 71.6 1.1 0.0 19.7 2.5 28.8 40.0 8.1 0.4 13.7 27.0 7.0 87.8 29.5 4.9 50.9 11.5 13.5 12.6 9.7 13.6 47.3 9.7 31.1 2.9 3.2 25.8 20.6 0.9 3.1 18.9 2.4 26.6 7.6 38.2 HDAC8 "HDACL1, MRXS6, RPD3, WTS" ENSG00000147099 "Histone deacetylase 8" Q9BY41 X 72329516-72573103 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease mutation, FDA approved drug targets, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048560 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA048560: AB_2680442" "unprognostic (1.42e-1)" "unprognostic (6.62e-3)" "unprognostic (3.20e-2)" "unprognostic (9.24e-3)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (4.64e-2)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (2.81e-2)" "unprognostic (3.17e-2)" "unprognostic (9.68e-2)" "unprognostic (8.42e-2)" "unprognostic (2.33e-3)" "unprognostic (9.10e-2)" "unprognostic (7.15e-3)" "unprognostic (2.12e-3)" 9.6 22.5 14.7 9.9 16.2 10.2 12.4 31.4 20.6 12.6 10.4 13.9 11.5 8.6 12.3 28.2 11.0 9.4 9.4 12.6 15.0 15.2 16.8 18.6 10.2 9.6 14.9 9.4 12.8 15.9 13.6 22.0 11.2 19.3 13.3 12.8 14.3 12.2 10.3 10.4 9.3 8.4 13.1 12.2 9.5 10.7 3.6 14.0 8.0 15.0 8.2 11.9 10.4 10.1 9.4 12.8 19.7 13.2 7.7 11.4 7.7 12.5 17.1 12.6 17.4 17.3 12.9 8.7 7.3 14.1 11.2 12.7 12.4 12.9 8.7 23.0 10.0 17.5 9.2 23.5 14.2 14.9 14.3 16.7 11.5 22.0 14.4 9.5 19.1 20.4 13.5 10.4 13.7 10.3 15.9 17.2 11.7 12.8 24.4 14.9 15.8 8.9 25.1 17.5 19.3 24.8 12.2 16.2 15.6 19.5 13.2 9.0 19.7 17.1 13.7 17.5 16.4 6.9 16.3 12.9 9.2 13.3 13.2 8.1 9.4 15.0 11.1 12.5 21.1 11.9 7.2 13.2 19.7 8.8 11.8 6.9 9.4 9.5 7.3 12.8 9.1 7.6 7.1 0.7 7.7 10.5 4.8 11.4 7.7 14.7 16.2 31.4 20.6 15.0 15.2 14.9 9.4 19.3 14.0 3.0 18.8 8.1 10.0 5.5 16.0 10.8 12.7 13.4 10.3 7.0 41.2 14.3 8.3 11.9 0.5 10.5 8.1 0.0 10.7 11.6 8.6 13.3 11.5 9.7 13.8 22.3 8.7 11.6 7.8 1.3 10.9 10.6 6.8 6.4 9.1 10.8 10.1 2.9 9.9 17.8 16.8 25.8 9.5 5.1 0.7 5.5 11.3 11.4 9.7 10.9 HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 16 "Early spermatids: 197.2;Late spermatids: 49.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 29.5" "Group enriched" "Detected in many" 9 "B-cells: 21.8;dendritic cells: 29.5;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HAP1: 55.1;hTERT-HME1: 26.4;SH-SY5Y: 22.0;U-698: 21.8;WM-115: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" 10.7 13.5 12.6 10.7 16.2 5.9 8.4 19.1 16.9 11.6 7.4 11.3 7.5 3.8 17.8 6.7 4.7 10.5 7.5 14.9 13.1 12.0 3.9 3.1 5.7 18.9 13.9 14.9 3.0 2.7 3.0 17.7 6.8 11.2 12.5 6.2 9.7 6.9 16.5 15.5 3.8 8.4 14.4 17.6 17.4 9.1 8.7 18.2 2.9 5.5 5.4 19.3 7.1 9.6 21.8 29.5 0.5 9.7 2.0 2.1 4.5 12.5 0.0 2.1 0.0 0.3 2.8 0.0 0.7 7.4 3.1 5.3 0.1 4.1 5.4 13.9 8.3 17.1 1.9 55.1 1.0 8.1 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 1.0 1.0 9.8 26.4 2.7 0.1 0.8 0.0 8.4 4.3 0.0 0.5 1.1 6.7 0.0 1.2 1.5 0.8 3.1 1.7 3.3 3.9 22.0 0.1 0.1 4.0 3.3 0.2 4.9 0.5 11.4 3.6 0.6 7.1 9.7 4.1 21.8 3.0 0.5 22.5 0.1 9.7 0.0 1.7 6.7 1.7 21.8 0.6 0.8 29.5 16.3 0.0 0.9 0.5 2.0 3.8 6.4 2.1 4.5 12.6 16.2 19.1 16.9 13.1 12.0 13.9 14.9 11.2 18.2 6.0 3.2 26.4 0.4 2.2 32.0 12.1 0.0 1.4 4.5 0.0 15.7 0.1 3.3 6.6 197.2 11.1 0.0 0.0 0.6 0.1 5.7 1.4 1.1 0.8 10.5 19.1 6.9 13.5 45.7 49.8 1.4 31.1 15.1 0.0 0.4 5.0 7.0 0.2 0.7 0.0 27.3 6.5 6.9 10.3 8.8 1.8 0.1 8.7 0.0 2.0 HDDC3 MGC45386 ENSG00000184508 "HD domain containing 3" Q8N4P3 15 90929964-90935196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040895 Approved Approved Nucleoplasm,Cytosol No No "Nucleoplasm, Cytosol" "HPA040895: AB_10795494" "unprognostic (1.03e-1)" "unprognostic (3.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (3.75e-2)" "unprognostic (2.53e-1)" "unprognostic (3.57e-1)" "unprognostic (1.28e-1)" "unprognostic (5.93e-3)" "unprognostic (1.08e-1)" "unprognostic (1.91e-2)" "unprognostic (3.43e-2)" "unprognostic (2.26e-1)" "unprognostic (4.86e-2)" "unprognostic (3.15e-1)" "unprognostic (4.65e-1)" 14.3 18.8 16.3 8.9 17.1 10.7 11.3 10.3 17.6 8.2 13.1 9.3 12.6 12.4 5.4 12.8 7.7 12.7 7.1 15.2 12.9 12.3 14.7 18.3 7.8 9.0 14.6 12.5 10.3 30.3 15.1 10.4 10.4 11.0 8.7 11.1 9.7 24.8 14.0 14.2 9.3 17.1 6.1 11.4 13.1 11.2 4.5 8.2 11.8 12.0 10.1 10.7 7.5 7.5 19.9 25.3 5.6 15.6 16.4 21.5 14.3 6.7 8.3 2.9 3.5 6.7 6.8 4.9 4.5 6.2 4.3 6.3 4.1 14.0 12.7 4.8 3.8 3.4 10.5 6.1 10.6 3.6 16.1 12.9 16.0 3.2 9.3 13.7 6.1 7.9 5.9 16.8 7.8 14.0 6.8 9.4 10.6 12.7 11.5 3.8 9.8 8.3 5.3 2.4 25.5 8.5 7.0 1.1 20.3 8.8 7.1 7.4 4.7 3.8 10.7 11.4 6.4 16.2 16.5 5.3 2.7 5.9 4.4 5.8 18.8 21.1 8.8 9.8 12.0 7.9 5.6 11.8 4.7 14.0 15.6 18.4 19.9 18.4 16.2 15.9 17.5 21.5 15.7 2.8 16.4 14.2 25.3 17.4 14.3 16.3 17.1 10.3 17.6 12.9 12.3 14.6 12.5 11.0 8.2 26.8 6.1 27.0 11.4 4.9 12.4 0.8 43.3 20.1 19.4 15.7 3.9 39.0 64.6 34.0 3.9 14.7 23.8 23.3 49.1 27.5 8.7 13.1 6.9 33.8 39.5 14.3 19.1 15.4 12.9 2.4 13.3 18.0 13.5 48.7 31.2 29.5 27.9 30.6 11.0 53.5 35.3 6.5 7.3 16.3 14.0 7.3 20.3 17.5 34.4 10.3 HELB ENSG00000127311 "DNA helicase B" Q8NG08 12 66302545-66347645 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "T-cells: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.97e-1)" "unprognostic (9.06e-3)" "unprognostic (8.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.00e-1)" "unprognostic (5.22e-2)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-6)" "unprognostic (3.97e-3)" "unprognostic (9.19e-4)" "unprognostic (1.93e-1)" "unprognostic (9.50e-3)" 3.4 2.1 1.6 12.2 3.9 6.8 2.9 1.3 3.1 2.6 2.7 2.1 1.4 2.3 2.9 2.1 2.7 1.6 2.0 1.8 1.9 1.8 2.7 3.7 4.6 9.9 2.9 0.5 3.0 1.6 2.1 11.9 1.8 4.5 3.1 2.8 0.6 2.9 1.2 1.8 2.8 4.5 1.6 4.7 6.8 3.5 1.8 3.1 11.0 2.8 0.8 8.2 2.6 3.7 1.1 0.9 4.7 0.8 1.6 3.0 0.6 1.3 2.9 1.7 2.0 0.6 1.7 2.3 0.9 0.4 0.9 1.0 2.1 2.2 2.0 2.3 0.7 1.1 1.8 1.4 1.2 1.1 4.2 2.2 5.2 2.5 2.1 1.2 3.9 2.6 1.6 0.5 1.4 1.7 1.3 1.1 4.6 2.0 6.3 1.1 2.1 1.4 6.6 3.2 1.3 1.0 1.6 2.4 4.1 1.4 1.1 1.5 1.8 2.3 2.5 1.4 3.1 0.9 5.6 1.2 1.2 2.3 1.8 1.7 5.9 2.3 1.1 1.7 3.4 2.2 4.7 0.8 2.2 1.6 0.5 2.2 0.5 2.2 2.0 0.3 1.1 3.0 2.2 2.1 1.6 0.4 0.9 1.9 0.6 1.6 3.9 1.3 3.1 1.9 1.8 2.9 0.5 4.5 3.1 0.0 6.9 11.0 2.3 0.6 3.0 3.4 0.0 5.3 11.4 0.0 11.8 2.5 1.7 1.2 0.2 4.5 4.3 0.0 1.0 1.8 2.8 6.5 2.3 2.4 2.7 12.7 4.6 4.9 7.8 0.4 3.1 4.3 3.3 2.8 4.9 2.8 1.7 3.5 0.7 2.4 6.9 0.0 2.1 0.7 1.0 1.5 2.1 20.3 4.9 2.0 HELQ Hel308 ENSG00000163312 "Helicase, POLQ like" Q8TDG4 4 83407343-83455856 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036852, HPA036853" Approved Approved "Nucleoplasm,Nuclear speckles" NA NA "Nuclear speckles" Nucleoplasm "HPA036852: AB_2675349, HPA036853: AB_10672102" "unprognostic (4.58e-2)" "unprognostic (3.25e-2)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" "unprognostic (4.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.14e-1)" "unprognostic (5.13e-3)" "unprognostic (7.14e-2)" "unprognostic (8.62e-2)" "prognostic favorable (9.07e-4)" "unprognostic (2.03e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.54e-2)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" 10.5 20.8 6.3 12.2 7.8 7.2 10.4 12.6 9.2 10.7 9.8 9.3 8.2 5.6 9.9 8.7 8.2 9.1 9.0 10.5 6.2 5.7 11.9 10.0 8.0 15.3 6.8 5.7 17.4 8.1 13.3 20.7 11.7 9.0 11.4 7.2 11.0 10.0 10.4 14.6 8.7 9.8 8.0 8.4 14.4 8.4 10.7 7.4 18.5 14.3 8.3 13.4 10.2 9.2 10.1 4.6 6.8 4.7 5.5 9.7 2.9 4.3 3.3 7.1 4.6 8.7 9.2 3.7 6.5 9.8 8.5 8.4 3.1 4.5 12.2 5.2 5.6 5.8 4.4 8.6 4.8 8.9 7.0 3.8 7.3 5.4 4.2 5.6 8.8 18.0 7.1 6.5 6.7 7.0 7.5 6.7 8.2 9.6 10.7 8.6 5.1 8.0 6.3 3.6 6.9 2.4 6.2 8.2 4.3 7.0 2.7 5.8 4.8 6.3 6.9 7.1 7.1 4.3 9.5 5.1 6.4 5.6 8.2 5.1 9.9 4.2 10.3 5.4 6.7 7.1 5.4 3.7 6.8 5.7 4.0 5.4 5.8 6.3 6.4 4.6 10.1 9.7 8.7 2.3 5.5 4.7 4.5 7.8 2.9 6.3 7.8 12.6 9.2 6.2 5.7 6.8 5.7 9.0 7.4 3.0 9.4 10.0 8.0 3.8 9.2 9.2 7.6 22.7 7.9 5.2 7.9 9.6 10.0 5.1 20.9 7.1 3.5 0.0 4.8 8.1 6.4 4.9 7.0 4.0 9.1 6.4 0.0 10.4 5.6 5.8 12.0 8.4 6.8 7.2 4.5 9.1 4.7 6.0 7.4 8.8 13.2 0.0 8.2 20.0 12.8 3.3 9.6 13.1 5.2 4.7 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340919-72376476 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Hofbauer cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 20000000 Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 30.1 37.4 23.1 18.0 22.9 35.5 37.8 23.3 28.1 30.6 20.5 19.4 30.1 18.5 25.9 65.7 11.7 21.8 29.2 33.8 23.4 12.8 34.6 29.5 43.9 31.4 24.9 21.1 20.9 22.2 18.1 22.9 37.9 18.8 18.1 26.0 26.9 24.8 22.0 17.7 17.9 24.6 23.4 21.4 31.5 22.6 18.0 22.9 12.1 31.2 11.1 16.4 26.7 17.1 16.1 37.9 22.4 32.7 17.8 18.1 21.3 7.5 12.8 5.5 10.6 45.5 51.9 7.9 10.6 53.8 23.0 36.8 6.7 55.4 6.3 10.2 21.3 12.0 15.1 14.6 6.7 14.6 5.1 5.8 7.9 12.7 11.6 35.2 18.9 22.7 44.1 20.2 10.0 17.9 42.2 21.0 9.4 12.2 39.2 30.6 6.5 4.1 9.5 3.1 24.7 0.1 4.2 12.0 14.2 25.7 11.9 4.8 5.3 26.5 25.1 59.9 11.7 4.6 23.9 10.6 34.5 14.4 31.7 11.2 20.9 28.2 6.5 12.5 25.3 16.7 8.9 32.7 22.4 18.1 13.7 15.8 16.1 12.0 15.8 37.9 15.6 9.5 14.0 3.1 17.8 4.8 14.4 10.7 21.3 23.1 22.9 23.3 28.1 23.4 12.8 24.9 21.1 18.8 22.9 59.6 55.5 41.1 30.3 19.7 40.2 22.6 35.7 17.4 28.4 62.8 100.1 116.3 51.4 65.3 16.3 43.0 46.2 0.0 33.3 55.3 62.5 30.5 29.9 37.8 207.1 25.4 45.3 44.2 76.0 10.5 68.7 108.5 89.4 50.5 39.4 48.4 43.8 84.5 42.1 55.5 56.1 45.3 20.6 20.4 28.2 13.7 131.8 47.5 44.4 25.0 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 174.3" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 395.6;Hofbauer cells: 319.1;Syncytiotrophoblasts: 412.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 108.4;GAMG: 90.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" NA NA 43000000 "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 48.0 21.9 7.7 13.6 11.6 11.1 26.1 7.4 11.2 25.8 34.2 9.5 18.0 21.6 22.1 77.3 20.6 17.3 28.1 46.3 7.1 9.1 30.4 44.5 40.9 19.3 8.5 6.7 22.7 30.4 21.8 14.3 174.3 9.3 22.6 26.3 21.0 34.6 13.3 21.0 15.3 33.6 21.0 8.7 20.5 20.7 16.2 6.1 10.8 33.7 15.2 15.4 24.0 19.7 8.9 59.8 23.8 65.9 7.6 16.4 42.9 20.3 16.0 5.6 18.5 108.4 33.5 18.2 25.0 81.1 24.4 53.0 18.8 26.6 0.0 19.8 20.5 90.2 16.4 6.0 25.4 32.3 11.4 10.8 2.6 15.5 14.1 31.8 2.2 22.0 29.5 15.0 25.6 17.2 38.5 27.9 6.4 7.5 33.3 26.7 20.6 2.6 5.1 5.2 19.3 7.2 6.2 8.1 26.5 16.8 18.6 3.6 4.5 19.4 13.2 24.1 10.1 13.9 15.1 16.6 16.1 4.0 29.6 23.0 15.4 26.5 0.1 36.7 20.0 29.2 14.5 65.9 18.6 14.2 24.5 16.4 8.9 11.7 13.1 59.8 5.5 11.2 10.9 23.8 7.6 14.6 18.0 13.7 42.9 7.7 11.6 7.4 11.2 7.1 9.1 8.5 6.7 9.3 6.1 38.7 35.5 39.5 70.4 39.0 9.5 18.9 63.7 20.1 18.2 27.9 7.9 395.6 16.6 123.0 1.1 60.6 71.9 0.0 111.0 143.1 100.1 65.8 69.2 62.8 319.1 9.5 21.9 83.4 134.6 1.7 78.9 151.2 69.2 83.8 50.0 34.8 68.2 51.8 67.8 65.5 10.6 45.3 54.5 0.2 1.1 28.4 412.8 37.3 76.2 54.8 HEXDC FLJ23825 ENSG00000169660 "Hexosaminidase D" Q8WVB3 17 82418318-82442645 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 30.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022834, HPA023379, HPA027844" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Nucleoli fibrillar center, Mitochondria" "HPA022834: AB_1850641, HPA023379: AB_1850643, HPA027844: AB_10600711" "unprognostic (8.69e-3)" "prognostic favorable (7.70e-4)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.51e-2)" "prognostic favorable (2.71e-4)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.14e-2)" "prognostic favorable (5.57e-4)" "unprognostic (9.04e-3)" "unprognostic (1.83e-1)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (1.24e-1)" "prognostic favorable (2.52e-5)" 12.7 8.5 7.1 16.6 9.3 14.3 8.7 13.2 7.3 10.1 7.6 8.8 12.8 8.0 10.0 11.1 7.9 10.3 9.4 5.7 7.2 4.6 9.9 11.6 12.4 11.6 12.8 5.5 13.6 72.9 10.2 14.6 5.7 7.4 14.1 4.2 7.0 13.3 9.2 20.4 11.3 12.3 6.0 6.1 15.6 8.8 4.7 11.4 8.6 11.7 8.6 10.7 8.3 8.8 5.9 30.3 3.3 11.5 11.9 9.8 4.4 3.0 7.7 3.4 5.3 10.4 9.0 10.5 3.9 4.8 4.1 4.7 2.7 10.4 8.1 4.3 1.6 2.8 4.3 2.0 2.3 1.9 5.6 13.1 3.6 6.8 4.5 9.3 2.4 9.3 6.4 2.3 1.1 4.2 5.6 5.3 6.2 4.6 2.8 1.1 7.0 8.4 9.0 3.1 5.6 4.7 10.0 2.9 15.8 3.1 4.6 4.8 10.2 8.1 5.3 7.3 1.6 8.5 9.2 5.3 2.7 5.1 2.0 2.7 12.7 2.4 6.0 2.1 6.9 2.7 3.3 1.7 2.7 9.8 11.5 6.5 4.6 2.2 3.4 2.0 5.9 3.5 5.1 3.0 11.9 4.9 30.3 1.4 4.4 7.1 9.3 13.2 7.3 7.2 4.6 12.8 5.5 7.4 11.4 3.0 8.5 8.3 9.5 4.1 19.2 4.4 12.7 9.4 12.5 17.4 17.7 4.7 8.3 5.4 1.2 8.0 16.8 0.0 8.2 5.3 6.2 10.5 10.3 12.9 13.7 39.7 13.3 16.0 9.5 2.1 33.1 11.5 5.0 16.2 14.4 18.7 5.8 10.1 23.3 6.1 29.0 19.4 6.2 6.0 10.2 2.0 3.3 12.9 12.0 7.5 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "HFM1, ATP dependent DNA helicase homolog" A2PYH4 1 91260766-91404869 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;testis: 19.9" "Cell type enhanced" "Detected in some" 22 "Early spermatids: 10.1;Spermatocytes: 40.0;Spermatogonia: 7.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.3;AN3-CA: 4.9;K-562: 5.0;SCLC-21H: 3.1;SH-SY5Y: 3.8;U-266/70: 4.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Golgi apparatus, Vesicles" "HPA035036: AB_2797224, HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.8 0.7 2.6 0.3 4.1 0.4 0.8 11.3 4.4 1.7 0.9 1.5 2.7 0.6 3.7 2.5 0.4 1.2 0.6 1.0 2.3 0.9 1.3 0.4 0.5 1.6 0.7 1.4 6.4 1.2 0.1 7.8 0.9 3.9 1.1 0.7 2.7 1.0 2.0 2.3 0.4 0.5 1.7 4.7 0.7 0.6 19.9 1.5 0.0 2.7 0.5 0.4 0.7 2.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.3 4.9 0.0 0.2 0.1 0.5 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.1 0.2 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.6 0.2 2.4 0.0 0.0 0.3 1.4 0.1 0.0 0.0 3.1 3.8 0.0 0.0 1.3 2.6 0.0 0.8 0.1 0.0 1.0 0.9 0.1 4.4 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.6 4.1 11.3 4.4 2.3 0.9 0.7 1.4 3.9 1.5 0.0 0.6 0.0 0.0 0.0 3.7 2.6 0.0 0.0 0.0 0.0 5.9 0.4 0.0 0.2 10.1 0.3 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 3.7 0.0 0.0 0.0 0.0 3.1 0.1 0.0 2.1 0.0 6.4 0.0 0.3 40.0 7.8 0.0 0.0 0.0 0.0 0.0 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 262.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 90000 Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 13.7 38.6 18.1 10.1 19.5 5.0 15.8 16.4 18.7 16.3 15.8 14.5 13.0 24.7 17.0 13.0 20.2 10.2 10.0 13.7 18.5 12.7 65.7 56.8 7.6 8.2 20.1 10.8 9.5 29.5 35.8 24.7 7.8 21.0 11.7 18.7 15.0 10.6 12.2 17.5 23.7 16.5 11.3 18.2 9.0 10.4 10.6 22.2 10.5 17.4 15.4 9.3 12.5 49.2 24.2 15.1 14.6 7.6 17.3 20.0 7.3 9.8 7.6 16.3 10.3 15.4 13.6 9.0 10.7 5.7 10.1 11.0 23.5 8.7 15.0 15.3 9.2 7.2 18.9 17.2 14.7 15.3 21.5 13.4 20.0 15.9 20.5 5.2 14.2 7.4 11.0 7.9 11.8 2.1 14.8 16.3 14.3 24.2 13.1 11.0 9.1 14.5 16.4 5.1 13.4 15.5 18.0 11.7 38.0 22.8 29.9 12.4 11.7 9.2 13.2 30.2 24.8 14.9 11.1 11.5 10.7 10.0 7.2 7.5 8.4 17.8 12.5 9.7 12.4 8.4 12.9 6.7 14.6 11.9 7.6 12.8 24.2 13.3 12.5 11.1 18.7 14.2 18.2 3.5 17.3 5.7 15.1 20.0 7.3 18.1 19.5 16.4 18.7 18.5 12.7 20.1 10.8 21.0 22.2 20.8 19.6 31.1 98.9 49.7 35.7 23.4 40.8 28.1 28.4 34.9 96.2 40.5 97.8 21.8 145.2 29.2 35.8 0.0 25.6 16.9 26.6 30.4 10.3 97.2 29.6 23.8 36.2 76.7 17.4 44.8 32.2 15.7 43.9 14.4 25.9 37.9 16.2 17.3 42.8 262.7 51.0 38.8 26.4 17.5 27.2 35.5 16.7 21.3 53.3 81.2 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066571 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "kidney: 55.4;liver: 146.5;pancreas: 80.1" "Group enriched" "Detected in many" 7 "Hepatocytes: 406.8;Proximal tubular cells: 178.8" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.2;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 5 "T-cells: 1.2" "Group enriched" "Detected in some" 9 "EFO-21: 19.8;Hep G2: 28.1;T-47d: 13.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 1000000 "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 0.2 0.0 0.3 0.1 0.5 0.0 3.2 0.4 1.1 0.3 0.3 0.2 8.4 0.2 1.1 10.7 0.1 1.9 3.2 0.7 0.6 0.3 55.4 146.5 4.9 0.1 0.9 0.2 0.4 80.1 2.6 3.2 0.2 0.4 5.3 0.0 0.4 4.1 8.5 8.5 0.0 0.2 0.1 0.9 0.3 6.9 0.8 0.3 0.1 4.3 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.1 0.0 0.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.1 0.1 0.0 0.1 0.3 13.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.6 0.2 0.5 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.5 0.4 1.1 0.6 0.3 0.9 0.2 0.4 0.3 8.9 26.7 17.7 4.9 0.1 4.5 2.4 35.7 0.0 2.3 31.4 0.0 0.0 44.7 3.3 7.0 0.3 0.0 0.0 23.6 0.3 0.2 7.9 2.3 406.8 0.8 0.0 2.4 8.0 10.0 20.0 0.0 0.5 0.0 1.0 1.7 1.3 23.4 0.0 0.4 178.8 0.5 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.5 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 11 "Hofbauer cells: 15.9;Kupffer cells: 27.7;Macrophages: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 17.8;neutrophil: 12.8" "Group enriched" "Detected in many" 5 "granulocytes: 12.8;monocytes: 17.8" "Cell line enhanced" "Detected in many" "Karpas-707: 23.3;OE19: 20.5" "Region enhanced" "Detected in some" "olfactory region: 4.5" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 9700000 Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 4.9 5.1 3.0 6.8 3.5 2.2 1.2 0.8 2.4 3.6 6.2 7.1 0.0 2.3 2.9 2.8 14.5 5.7 3.0 5.8 3.2 1.5 3.0 5.6 8.2 16.1 7.1 1.4 7.5 1.1 15.5 2.3 11.3 3.4 1.1 7.0 0.7 12.5 2.1 0.7 6.9 3.6 2.1 7.0 19.0 2.4 6.0 2.8 1.6 1.4 16.9 9.7 2.4 4.9 0.3 1.9 12.8 17.8 1.4 3.4 4.8 7.6 0.3 0.0 1.0 1.8 0.5 0.0 0.9 4.2 1.9 8.1 0.2 5.7 0.2 1.4 2.1 13.0 7.4 9.7 1.3 3.4 0.7 0.9 2.0 5.5 0.1 1.0 1.3 4.6 0.8 2.9 1.3 9.2 0.8 10.2 1.3 0.0 23.3 0.8 1.6 0.1 0.1 0.4 20.5 1.4 0.0 0.3 0.3 5.3 0.2 5.5 0.0 10.6 5.9 0.8 1.5 0.8 1.8 11.8 0.8 2.7 0.8 0.9 0.3 3.6 0.1 6.1 6.2 1.4 0.2 17.8 0.0 1.0 6.7 0.7 0.2 1.9 0.7 1.9 0.3 1.4 1.2 12.8 1.4 0.9 0.1 3.4 4.8 3.0 3.5 0.8 2.4 3.2 1.5 7.1 1.4 3.4 2.8 6.0 4.1 0.0 2.6 3.1 0.0 0.4 0.0 2.7 3.4 1.8 0.0 0.5 0.0 1.3 0.6 0.6 5.1 0.0 1.2 2.3 0.6 1.5 0.0 0.2 15.9 0.0 6.3 3.1 27.7 0.0 0.6 10.2 0.0 0.0 2.9 0.0 0.8 8.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 3.1 1.3 3.2 4.6 3.7 HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241330 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Basal glandular cells: 1106.3;Syncytiotrophoblasts: 1110.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 1000000000 Cytosol "CAB005221: AB_631616, HPA038845: AB_10673477, HPA038846: AB_10673478" "unprognostic (3.98e-2)" "unprognostic (2.50e-3)" "unprognostic (6.64e-2)" "unprognostic (9.60e-3)" "unprognostic (1.54e-3)" "unprognostic (6.02e-3)" "unprognostic (9.08e-3)" "unprognostic (9.11e-3)" "unprognostic (4.50e-2)" "unprognostic (7.45e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (3.66e-2)" 44.2 40.3 26.3 40.8 38.4 125.0 58.8 19.5 26.9 37.7 29.3 19.8 47.0 25.5 31.6 75.3 34.1 31.1 25.5 72.7 23.3 28.6 60.4 147.6 43.6 32.7 34.3 14.3 36.2 110.3 41.1 47.6 62.6 43.5 34.3 33.0 16.5 84.9 40.7 23.9 32.3 38.3 33.8 28.2 33.8 35.1 33.0 41.5 23.2 219.3 21.7 29.8 50.4 75.1 33.3 53.8 57.4 55.3 51.9 63.0 90.0 35.5 24.0 31.7 41.8 37.9 43.9 74.7 64.1 50.9 47.7 56.0 37.2 71.1 41.1 40.0 46.7 103.4 45.5 28.3 57.2 51.3 23.8 14.3 24.6 30.1 67.1 200.5 33.5 46.6 27.0 112.4 38.2 167.8 50.6 74.0 8.7 18.2 57.5 34.6 26.3 14.7 23.7 35.8 87.0 24.2 14.0 32.3 66.6 46.2 23.5 16.4 29.2 40.7 43.7 65.3 51.1 45.0 24.5 49.6 29.1 28.3 29.7 29.7 60.2 57.4 34.8 70.6 28.3 43.8 57.4 55.3 44.3 61.9 54.8 63.0 33.3 45.7 57.7 48.6 24.9 37.6 46.6 44.3 51.9 35.5 53.8 31.2 90.0 26.3 38.4 19.5 26.9 23.3 28.6 34.3 14.3 43.5 41.5 172.7 228.8 134.1 1106.3 260.1 93.3 493.6 73.9 190.1 253.6 106.4 331.8 423.2 38.1 330.8 34.2 189.6 316.5 46.7 227.7 576.5 389.6 402.8 329.8 324.2 392.1 60.4 487.5 159.0 114.8 42.9 162.3 280.8 172.1 141.5 125.9 124.7 293.4 101.7 164.1 109.1 122.6 116.4 222.8 360.8 228.7 206.6 1110.2 140.9 109.4 772.3 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486581-197516737 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 162.6" "Cell type enhanced" "Detected in all" 5 "Basal glandular cells: 1171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 53000000 Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 28.5 125.2 28.7 23.4 31.8 21.0 55.9 18.2 24.3 17.4 30.3 17.8 23.3 28.9 17.5 18.5 27.2 25.3 16.3 24.0 24.2 27.8 67.1 147.5 22.4 25.3 35.5 16.1 30.2 50.6 32.5 25.9 27.1 33.6 25.9 37.2 11.9 17.6 21.0 36.4 13.7 32.0 23.6 32.4 22.7 25.2 10.9 35.8 22.7 38.7 29.4 30.3 33.3 162.6 25.6 30.3 6.2 29.3 23.1 33.5 22.2 41.2 50.8 42.6 38.2 29.2 30.6 62.0 43.0 22.7 51.8 38.0 170.3 24.9 125.5 56.1 22.4 64.2 42.2 166.7 47.4 73.5 30.8 66.9 89.1 82.2 197.1 27.5 98.7 28.0 34.5 55.0 45.9 80.9 36.5 40.6 69.3 109.7 49.2 38.0 52.8 61.2 99.9 84.2 54.3 106.3 73.7 52.6 90.6 54.4 43.2 55.8 31.7 43.1 46.7 55.2 91.1 32.3 58.6 18.1 32.2 44.7 41.4 67.9 27.6 60.7 104.2 37.8 59.7 34.5 4.5 19.7 5.3 15.5 29.3 28.8 25.6 25.0 21.8 30.3 21.0 33.5 29.0 6.2 23.1 25.8 20.2 19.7 22.2 28.7 31.8 18.2 24.3 24.2 27.8 35.5 16.1 33.6 35.8 154.9 133.3 218.4 1171.9 219.0 70.0 213.1 150.3 448.3 361.7 75.0 241.5 780.7 318.3 195.2 4.9 145.2 151.1 70.0 125.9 299.2 219.4 456.8 297.3 264.5 289.1 90.6 262.9 61.4 70.1 9.9 120.8 249.2 155.3 160.5 166.4 117.0 164.4 153.9 106.8 589.7 103.4 84.1 310.2 68.2 82.2 181.0 837.2 136.4 347.8 853.1 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529377-74533348 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 116.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA Mitochondria "CAB004004: AB_326421, HPA006602: AB_2667622, HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 16.4 12.7 10.6 14.9 11.3 18.9 12.9 10.7 17.7 12.3 12.8 12.6 9.7 12.6 12.9 6.9 10.7 10.6 9.0 12.9 11.6 8.7 13.1 11.4 11.3 13.2 10.8 11.9 18.7 12.9 10.5 9.0 10.4 13.5 11.6 5.5 10.2 13.1 9.2 17.6 9.0 12.6 11.8 9.1 17.3 11.8 13.9 12.6 12.2 16.8 12.6 9.3 10.4 15.2 12.9 9.4 5.9 8.1 5.5 7.8 7.0 8.0 5.0 5.7 5.0 7.9 3.2 15.4 7.0 3.7 4.2 2.5 9.2 3.6 7.3 5.5 4.0 11.8 9.1 6.8 8.0 1.1 16.4 13.6 14.6 4.8 8.1 7.4 6.8 10.7 3.8 5.4 8.0 6.8 6.8 5.3 12.3 19.1 10.8 3.2 5.3 12.6 14.4 4.8 9.6 14.3 8.6 16.3 8.0 3.5 3.3 6.7 8.0 3.8 8.6 13.3 3.4 3.9 6.6 3.7 7.4 9.1 14.9 15.6 13.3 4.4 4.7 6.4 10.8 5.9 5.9 8.1 4.8 7.3 6.2 7.8 12.9 7.3 6.2 9.4 11.6 6.3 6.4 3.2 5.5 4.7 6.6 7.4 7.0 10.6 11.3 10.7 17.7 11.6 8.7 10.8 11.9 13.5 12.6 0.0 3.7 23.9 16.6 18.3 12.1 0.8 17.8 9.4 9.1 10.4 0.0 20.6 29.9 26.3 24.4 29.4 13.6 116.8 15.4 31.8 26.6 15.0 26.5 10.6 27.5 9.5 8.6 16.5 9.5 32.5 23.0 17.8 28.7 36.1 10.3 19.0 22.8 14.2 19.4 29.1 11.9 25.8 26.4 55.8 34.3 19.3 16.9 25.4 19.8 12.9 HYAL1 "FUS2, HYAL-1, LUCA1, NAT6" ENSG00000114378 "Hyaluronoglucosaminidase 1" Q12794 3 50299889-50312381 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 105.8" "Cell type enhanced" "Detected in many" 15 "Hepatocytes: 116.0;Proximal tubular cells: 50.7" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 7.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.3" "Group enriched" "Detected in some" 4 "Hep G2: 45.8;SK-BR-3: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 15000 "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 4.9 6.3 1.0 0.9 1.3 0.0 8.4 0.9 1.4 2.9 1.8 1.7 1.3 1.2 3.5 3.5 5.8 1.9 19.3 18.2 1.1 0.5 25.0 105.8 11.3 2.5 1.2 0.9 1.9 3.1 8.0 0.8 1.3 2.9 1.4 1.0 3.1 3.6 1.2 5.2 5.8 1.4 2.7 1.2 28.0 7.2 1.7 0.8 0.2 3.1 4.2 1.0 1.3 4.3 1.2 1.1 7.3 0.9 0.7 1.5 0.2 1.3 0.8 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.0 0.2 5.2 1.4 0.0 0.4 0.2 0.3 3.1 0.1 0.2 0.0 0.0 0.0 0.1 3.9 45.8 2.1 0.3 0.3 1.9 6.6 0.0 0.2 0.4 1.3 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.3 3.3 0.2 0.0 0.1 0.1 2.7 0.1 0.1 1.0 0.0 13.3 0.1 1.2 1.0 0.1 0.9 0.3 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.3 0.1 2.2 0.9 2.9 0.7 0.3 1.5 0.9 0.7 1.0 0.4 1.2 1.5 0.8 7.3 0.7 0.7 1.1 0.9 0.2 1.0 1.3 0.9 1.4 1.1 0.5 1.2 0.9 2.9 0.8 17.9 14.4 0.0 0.2 2.6 1.1 19.5 17.8 1.4 0.0 10.4 3.9 0.0 19.9 13.8 7.3 16.5 0.7 0.0 13.2 0.0 1.0 0.2 0.0 116.0 0.1 0.0 1.7 30.1 4.0 6.7 2.0 0.9 0.0 0.0 0.8 0.2 7.9 0.0 1.1 50.7 0.5 6.5 2.3 0.0 1.0 2.8 0.6 0.0 0.2 1.6 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronoglucosaminidase 2" Q12891 3 50317790-50322906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.0" "Group enriched" "Detected in many" 4 "Endothelial cells: 160.0;Ito cells: 253.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 68.6;TIME: 93.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 46.5 16.4 5.4 11.0 13.9 1.2 52.1 3.5 7.6 16.0 9.5 6.6 9.0 7.3 18.8 11.3 16.0 16.5 19.9 33.6 11.1 6.0 35.7 20.2 61.1 25.6 7.5 4.0 13.6 11.2 7.9 11.9 34.4 16.3 10.3 4.8 20.4 10.9 9.7 11.6 9.7 9.9 15.1 8.0 107.0 10.2 8.6 5.5 1.1 23.2 16.0 8.3 14.8 20.2 0.9 4.4 8.6 11.3 2.0 3.4 2.6 4.9 7.3 12.0 12.2 7.4 6.5 7.8 5.9 7.7 8.0 6.3 8.3 14.6 1.3 20.2 8.0 15.9 5.2 4.5 10.9 2.1 2.7 3.9 1.7 6.8 12.6 6.4 1.4 4.8 10.1 9.2 8.1 2.6 7.3 68.6 3.4 3.2 1.5 6.6 6.7 3.2 3.0 14.0 4.3 11.3 2.9 2.4 4.8 9.9 4.4 3.2 10.5 5.8 6.0 5.9 4.2 6.6 3.7 93.9 9.7 9.9 6.5 8.8 2.8 4.4 4.0 5.7 4.7 14.0 0.0 8.0 8.6 1.3 11.3 2.8 0.9 1.1 3.4 4.4 0.9 0.4 0.6 7.6 2.0 10.4 3.3 1.4 2.6 5.4 13.9 3.5 7.6 11.1 6.0 7.5 4.0 16.3 5.5 17.9 6.9 3.0 22.2 11.6 6.2 6.5 17.8 4.0 2.3 31.4 5.9 25.4 10.0 47.4 4.0 160.0 12.7 0.0 34.5 32.3 14.1 25.0 0.0 9.7 38.3 7.9 7.0 253.5 15.5 4.2 22.7 8.6 16.9 8.2 10.7 19.8 35.0 14.0 20.8 10.5 5.5 38.8 13.3 5.9 45.9 11.0 27.3 5.7 15.0 28.5 HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronoglucosaminidase 3" O43820 3 50292831-50299468 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 26.9;bone marrow: 48.8;brain: 12.5;testis: 31.1" "Group enriched" "Detected in many" 16 "Early spermatids: 73.0;Late spermatids: 206.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.1;eosinophil: 26.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 26.9" "Cell line enhanced" "Detected in many" "HEL: 22.4;HMC-1: 40.2;THP-1: 41.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049402 Uncertain "Secreted to blood" NA NA "HPA049402: AB_2680746" "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.12e-5)" 3.5 4.2 6.3 3.1 8.8 48.8 3.3 11.4 12.5 4.2 3.6 3.8 6.1 3.8 2.7 5.1 5.6 3.7 5.4 3.4 6.4 5.6 2.9 7.0 3.2 4.2 5.3 5.6 4.3 3.7 2.6 3.1 3.6 11.1 4.9 2.9 3.7 6.7 5.6 3.9 3.0 4.1 4.6 3.4 2.8 6.6 31.1 2.7 3.0 3.3 5.1 3.7 4.8 3.8 1.1 4.2 26.9 2.1 1.0 2.2 1.2 2.2 2.6 1.5 1.7 3.1 1.6 0.9 2.5 2.2 3.2 2.4 3.5 2.4 2.0 1.2 2.9 4.9 2.5 2.7 5.9 1.2 4.6 1.4 22.4 6.8 2.8 2.2 2.4 40.2 3.3 4.5 3.2 2.1 2.3 3.2 2.2 1.7 2.5 1.5 1.3 0.9 14.2 1.1 2.6 6.6 1.0 2.0 3.6 3.8 1.0 1.8 2.1 3.6 2.9 2.0 1.8 1.9 41.3 4.3 2.7 1.9 8.6 1.4 1.2 2.5 1.5 2.4 8.6 2.2 12.1 2.1 26.9 0.7 1.1 1.2 0.9 2.2 1.0 4.2 1.1 0.6 0.8 0.7 1.0 0.7 1.1 1.3 1.2 6.3 8.8 11.4 12.5 6.4 5.6 5.3 5.6 11.1 2.7 3.0 1.4 0.0 2.2 2.7 1.5 0.3 0.0 1.4 4.5 3.5 3.9 2.5 8.3 4.5 73.0 3.4 0.3 0.0 0.6 4.1 1.8 2.3 6.9 1.0 2.0 4.8 4.1 7.4 1.8 206.1 1.7 2.8 3.3 9.0 1.2 1.5 3.1 0.0 2.5 1.9 0.4 6.5 3.1 4.3 3.8 3.1 2.5 1.3 1.6 3.0 HYAL4 ENSG00000106302 "Hyaluronoglucosaminidase 4" Q2M3T9 7 123828983-123877478 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 7.1;skeletal muscle: 8.3" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 4.0;Extravillous trophoblasts: 5.9;Spermatogonia: 2.8;Syncytiotrophoblasts: 1.8" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 4.5;CAPAN-2: 7.2;RT4: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA029453 Uncertain NA NA "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.5 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.0 0.4 0.0 0.0 0.6 0.1 0.4 0.0 0.0 0.1 0.6 0.0 0.1 7.1 0.2 0.0 1.2 0.0 8.3 1.4 0.2 0.0 0.1 1.0 0.2 3.4 0.4 1.5 1.0 0.1 1.3 0.6 3.3 0.6 1.0 0.9 0.1 0.3 0.6 0.1 0.4 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 7.2 0.3 0.4 0.0 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.2 0.1 0.0 17.0 0.2 0.1 0.0 1.0 0.0 1.4 0.4 0.2 2.4 0.1 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.5 0.4 0.6 0.5 0.5 0.4 0.5 0.5 0.2 1.3 0.7 0.9 3.3 1.0 0.6 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 5.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.0 1.8 0.0 0.0 0.1 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574076 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Intracellular and membrane" NA NA 140000 "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 9.8 13.1 6.9 11.7 8.8 6.0 19.8 8.6 9.4 10.5 9.9 6.5 17.5 7.4 10.2 15.9 13.0 8.4 9.6 13.6 5.8 5.3 13.3 21.3 7.9 9.2 8.9 5.1 7.7 15.7 19.4 11.1 9.4 7.6 11.6 10.0 10.5 11.0 17.2 31.1 45.2 10.7 14.3 8.8 9.9 10.3 18.1 7.5 13.5 12.0 13.9 10.7 11.5 9.8 7.4 11.3 3.8 13.7 7.7 10.6 5.5 12.3 18.4 14.4 29.4 14.0 11.8 7.9 11.0 26.1 11.6 9.9 18.7 14.8 17.5 16.3 16.0 10.9 16.0 18.9 12.1 7.6 21.0 11.6 8.7 15.4 16.4 12.3 26.6 13.8 8.3 11.8 13.6 19.7 16.4 19.5 7.4 16.2 12.5 13.1 8.3 8.8 10.5 11.4 13.8 7.3 12.3 13.4 11.2 17.1 23.3 6.7 9.3 14.8 10.6 9.7 15.6 15.2 7.5 18.1 7.5 8.5 7.8 14.2 11.4 14.3 18.8 10.9 21.3 5.2 2.3 8.2 3.8 6.7 11.4 5.9 7.4 7.9 6.5 11.3 5.3 6.0 6.4 0.5 7.7 13.7 4.4 10.6 5.5 6.9 8.8 8.6 9.4 5.8 5.3 8.9 5.1 7.6 7.5 8.9 10.2 2.2 5.3 4.6 14.0 39.2 7.6 24.1 6.8 7.0 45.2 9.9 1.7 11.7 31.2 8.0 10.7 0.0 17.4 4.7 5.5 10.9 1.1 22.4 10.4 6.4 10.4 14.7 18.1 7.7 6.1 8.6 8.5 1.8 11.4 7.5 14.5 5.8 9.6 8.8 26.3 6.5 7.5 18.0 10.8 14.3 3.2 4.3 8.3 7.8 IDS SIDS ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476990-149521096 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 107.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" NA NA 8900000 "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" 11.6 20.4 92.9 12.1 81.5 16.0 12.0 30.4 107.9 13.1 9.3 15.0 8.1 9.1 17.8 29.5 11.3 14.8 12.3 16.2 83.6 42.7 10.5 7.0 17.9 12.5 36.7 51.8 22.6 10.6 19.5 17.8 7.4 33.0 14.0 10.7 7.7 9.1 19.5 8.9 12.9 11.6 14.1 21.0 14.1 10.6 3.8 14.7 1.9 13.2 4.9 14.7 11.4 8.6 8.7 11.7 63.4 16.6 8.5 18.2 13.3 14.3 16.3 7.2 4.2 7.9 14.1 3.0 8.3 21.8 7.7 14.8 3.3 10.8 34.4 22.2 12.3 16.2 8.3 6.9 13.0 10.0 12.3 5.9 3.7 5.3 1.9 6.1 5.9 33.2 7.7 7.0 16.7 11.0 32.6 12.2 6.5 1.7 25.2 11.3 18.3 5.9 3.1 5.6 9.2 11.1 3.9 6.5 6.6 9.9 3.6 9.6 22.1 3.2 7.3 10.2 11.7 2.3 2.6 14.3 10.2 10.3 16.5 22.3 17.6 13.9 25.1 45.9 14.2 7.2 23.9 13.8 39.6 18.2 14.9 13.5 8.7 11.2 13.6 11.7 6.6 7.5 11.3 63.4 8.5 16.6 8.8 16.9 13.3 92.9 81.5 30.4 90.7 83.6 42.7 36.7 51.8 33.0 14.7 92.3 66.3 80.1 47.2 29.5 173.4 41.9 7.6 78.9 62.6 78.5 43.2 23.8 18.3 43.2 1.1 38.4 37.1 0.0 64.9 19.5 73.6 58.5 220.6 30.0 43.2 209.7 161.6 51.0 68.1 1.7 67.3 78.5 49.0 118.2 26.2 42.9 66.6 45.6 84.1 19.0 58.2 58.2 64.9 2.9 5.1 38.1 119.6 113.6 17.9 87.2 IDUA MPS1 ENSG00000127415 "Iduronidase, alpha-L-" P35475 4 986997-1004506 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 130000 Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" 11.0 15.0 14.7 12.0 15.3 10.8 12.9 36.5 15.7 12.4 9.2 10.9 16.9 17.1 13.0 13.4 7.7 12.1 15.9 8.9 13.4 6.5 13.4 10.7 12.8 11.2 11.6 10.0 14.6 22.6 13.0 15.2 4.0 12.8 14.5 6.0 14.1 20.2 15.8 6.2 16.8 11.8 7.3 9.0 15.3 21.3 4.7 12.6 7.6 14.0 3.4 10.0 10.4 11.2 0.8 4.1 0.0 3.8 3.1 4.5 1.1 3.1 5.8 0.0 2.4 13.4 4.8 8.8 8.4 7.4 2.9 1.7 2.0 9.9 1.3 9.5 5.7 2.9 1.9 0.3 1.1 0.6 8.4 0.4 5.0 6.0 0.7 5.6 4.0 13.5 9.2 4.2 2.3 0.0 4.2 2.0 3.2 2.5 0.1 2.8 3.4 2.8 4.2 1.9 9.7 5.5 7.6 0.0 1.4 4.7 6.2 0.1 3.8 0.9 0.0 4.8 1.3 6.8 3.4 8.8 15.7 1.7 8.8 2.3 32.6 3.7 1.6 7.6 5.5 3.8 0.0 3.5 0.0 3.3 2.7 4.5 0.6 2.7 2.6 4.1 0.8 3.4 2.0 0.0 3.1 3.8 2.5 1.3 1.1 14.7 15.3 36.5 15.7 13.4 6.5 11.6 10.0 12.8 12.6 6.0 5.3 0.5 8.6 3.2 1.9 2.4 0.0 0.0 1.2 7.0 3.9 0.4 0.0 1.6 0.7 3.7 4.2 0.0 2.1 1.4 5.1 7.4 2.3 2.4 5.8 0.0 10.3 6.2 4.6 0.2 18.1 3.5 5.0 0.0 3.6 1.9 1.6 6.0 9.9 1.3 2.2 0.0 3.9 1.4 1.5 1.6 0.3 5.0 3.5 5.8 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267079-162318703 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.9;BJ hTERT+ SV40 Large T+ RasG12V: 39.7;Karpas-707: 18.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002656 Approved NA NA "HPA002656: AB_1079344" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.85e-3)" "unprognostic (3.34e-1)" "unprognostic (1.39e-1)" "unprognostic (5.65e-2)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (7.29e-2)" 17.2 11.3 5.8 23.1 5.8 26.9 10.5 2.8 6.4 10.3 12.5 4.9 9.5 12.3 7.3 11.0 9.9 8.3 10.8 6.3 6.1 4.7 10.4 11.8 19.7 17.2 6.1 3.2 11.2 11.5 11.6 14.0 15.6 7.0 12.3 7.8 5.9 15.7 17.2 4.7 6.4 18.0 5.8 7.4 25.3 9.0 4.3 4.2 20.5 15.9 8.3 12.9 9.1 10.4 12.3 10.5 14.5 11.6 3.6 9.4 7.1 3.0 0.3 0.1 0.0 4.0 3.1 1.2 0.5 8.5 31.9 39.7 0.5 7.6 6.2 4.6 0.5 16.1 3.3 0.5 4.2 3.4 14.7 1.8 3.7 0.5 1.8 3.6 4.0 2.7 2.4 2.7 3.9 0.8 3.9 2.4 3.1 0.1 18.9 0.5 6.4 4.2 4.1 0.0 2.8 1.5 3.1 0.0 8.8 3.6 3.9 0.1 0.0 1.9 10.4 18.2 0.1 2.7 3.2 1.9 0.9 0.8 0.4 1.2 7.3 11.9 0.9 1.7 3.2 2.8 4.2 11.0 4.0 6.5 11.6 9.3 11.4 8.3 7.2 10.5 12.3 6.9 7.1 14.5 3.6 11.0 1.5 9.4 7.1 5.8 5.8 2.8 6.4 6.1 4.7 6.1 3.2 7.0 4.2 29.8 8.1 10.0 9.3 6.1 0.0 4.9 15.3 24.1 12.5 7.0 0.0 4.7 5.0 15.8 36.2 17.3 9.8 0.0 16.4 14.4 6.6 9.4 12.7 5.0 13.2 0.0 15.1 15.4 12.3 36.7 12.7 10.4 5.0 18.0 10.3 7.3 10.9 9.5 12.4 4.3 0.0 0.0 2.7 1.6 1.5 5.1 2.9 8.6 6.5 10.3 IGHMBP2 "CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7" ENSG00000132740 "Immunoglobulin mu binding protein 2" P38935 11 68903842-68940602 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Ribonucleoprotein, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004092, HPA060994" Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA004092: , HPA060994: AB_2684406" "unprognostic (1.17e-1)" "unprognostic (1.04e-1)" "unprognostic (7.17e-2)" "unprognostic (3.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.69e-1)" "unprognostic (3.59e-3)" "unprognostic (4.31e-2)" "unprognostic (3.81e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.29e-8)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" 7.2 6.0 6.9 8.1 11.0 13.8 9.4 17.7 14.9 8.1 14.6 8.3 14.3 9.7 12.0 5.4 8.8 8.5 7.8 7.7 6.6 5.3 6.7 8.7 7.3 7.9 4.6 7.0 9.4 9.6 7.7 6.0 6.5 6.6 9.0 6.1 7.9 12.7 10.0 12.2 11.7 9.4 8.1 4.1 8.9 9.1 36.9 5.7 10.0 7.3 5.9 8.8 8.8 8.3 5.0 3.3 4.7 12.1 2.7 5.1 2.7 8.0 9.3 5.6 8.9 4.5 3.5 8.4 8.1 5.1 10.0 6.6 18.8 8.1 7.0 11.4 4.1 8.1 12.9 9.3 5.1 4.2 8.3 7.8 10.0 10.9 6.1 5.2 7.6 9.5 2.6 6.1 10.6 5.4 5.0 5.1 12.4 11.7 9.0 3.4 6.3 11.9 13.6 4.9 11.0 9.8 10.0 8.4 8.6 4.7 7.3 8.9 6.5 9.6 8.2 19.1 3.8 12.7 5.7 6.9 8.6 7.6 11.5 8.3 10.1 7.7 8.1 6.1 7.4 7.8 0.0 3.9 2.2 5.1 3.3 4.7 5.0 3.4 4.0 3.3 3.3 2.4 3.3 4.7 2.7 12.1 2.5 4.0 2.7 6.9 11.0 17.7 14.9 6.6 5.3 4.6 7.0 6.6 5.7 6.0 10.6 2.9 3.6 5.0 9.1 4.3 5.1 2.7 6.8 1.8 19.6 3.9 1.7 4.8 77.4 5.8 3.5 0.0 4.3 3.8 5.0 6.2 6.9 4.7 5.0 11.1 2.9 2.5 3.2 25.6 7.2 5.2 1.7 8.2 3.4 6.6 4.9 5.8 6.7 2.0 9.6 0.0 6.6 20.9 6.5 5.8 5.6 5.1 4.3 4.8 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170401-238203729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA004752: AB_1851753, HPA056099: AB_2797255" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavorable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 17.0 17.1 19.4 31.3 22.2 34.6 24.2 34.1 23.4 18.7 23.4 29.5 22.0 20.5 23.0 22.7 19.4 19.0 21.8 20.9 20.6 19.8 17.8 20.8 27.1 25.7 23.9 21.4 22.1 24.1 17.5 24.7 18.1 22.7 21.5 18.9 20.2 19.0 24.9 32.8 19.4 19.0 26.5 19.8 22.2 18.1 21.2 25.5 23.9 22.6 19.0 24.8 18.1 26.1 18.9 20.7 24.1 18.1 17.4 23.8 16.2 17.9 11.7 17.3 16.9 13.5 9.0 17.7 19.0 12.9 19.3 16.8 10.8 9.6 11.5 4.9 13.7 23.1 15.4 22.3 15.8 19.6 20.5 22.2 29.8 11.6 23.7 20.8 19.0 23.6 9.4 10.9 20.5 20.7 9.5 14.4 15.7 22.9 7.5 16.4 21.6 19.1 25.9 16.1 17.0 11.3 23.4 35.4 10.6 14.2 8.6 25.5 12.6 12.8 13.8 30.4 13.8 10.8 19.8 12.9 18.8 17.2 25.2 20.2 13.4 13.4 20.7 15.4 21.4 15.9 24.1 15.1 19.6 22.5 18.1 20.1 18.9 20.0 21.0 20.7 18.5 23.8 18.6 5.3 17.4 15.1 15.8 22.4 16.2 19.4 22.2 34.1 23.4 20.6 19.8 23.9 21.4 22.7 25.5 11.9 22.4 26.5 25.9 24.0 27.2 20.9 5.1 17.4 13.6 24.4 27.5 31.9 36.5 21.9 7.1 20.3 20.0 23.3 24.8 34.9 21.1 24.0 33.4 14.1 30.1 36.5 18.3 17.2 12.7 9.1 26.2 19.1 28.7 35.1 21.4 23.4 21.2 17.5 27.6 24.2 27.2 32.3 28.0 48.7 60.2 25.1 33.8 27.1 22.5 19.3 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81657961-81686693 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved NA No 390000 "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 10.8 10.9 16.2 10.5 20.9 20.8 9.2 11.2 29.7 9.4 22.4 15.3 4.7 20.1 10.8 12.0 17.2 10.3 11.0 22.3 17.6 19.7 25.5 29.4 9.8 14.3 18.9 20.7 12.1 8.5 8.6 20.1 7.2 27.3 10.6 25.4 14.8 8.9 7.3 11.2 5.0 23.5 15.0 19.1 12.9 12.2 30.5 13.8 16.2 20.3 12.0 13.7 10.5 10.7 13.2 8.2 24.1 7.5 13.6 12.9 7.2 5.7 16.0 11.1 8.4 6.5 10.3 4.6 16.8 12.1 15.1 18.2 7.5 9.2 22.0 13.4 11.9 22.5 4.5 12.9 5.8 20.3 23.0 13.1 16.6 8.8 9.3 11.7 16.6 17.0 9.8 8.4 11.5 22.8 14.1 16.3 17.1 15.0 18.7 15.0 3.6 21.0 9.6 4.8 14.6 17.1 9.9 8.4 9.0 17.4 18.8 4.5 19.2 11.0 3.0 20.1 19.6 9.6 13.3 12.6 12.5 15.9 9.5 20.7 21.9 26.0 30.8 14.5 10.0 16.9 24.1 4.7 19.5 9.9 6.6 12.1 13.2 10.1 10.7 5.0 9.5 10.7 12.6 7.5 13.6 7.5 8.2 12.9 7.2 16.2 20.9 11.2 29.7 17.6 19.7 18.9 20.7 27.3 13.8 14.9 10.1 13.7 15.3 12.2 16.6 34.7 15.3 20.1 15.9 8.7 13.7 7.9 26.6 13.3 3.5 15.0 29.2 0.0 17.7 8.2 9.7 14.8 32.3 31.0 12.5 23.8 20.6 13.5 13.2 6.4 14.4 14.2 11.8 28.9 15.6 22.6 14.4 51.8 14.2 23.5 14.6 12.9 15.6 46.8 16.2 7.5 2.5 20.8 17.2 15.7 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030883 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 90.1" "Cell type enhanced" "Detected in many" 8 "Distal tubular cells: 373.0;Extravillous trophoblasts: 196.1;Proximal tubular cells: 383.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 14.4;neutrophil: 18.7" "Group enriched" "Detected in many" 14 "dendritic cells: 5.3;granulocytes: 18.7;monocytes: 6.8" "Cell line enhanced" "Detected in many" "BEWO: 60.5;OE19: 67.8;RPTEC TERT1: 29.2;SiHa: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 6.2 2.8 1.5 5.2 1.9 6.9 10.7 0.3 1.5 6.8 12.2 0.7 1.6 5.6 7.3 3.0 40.3 4.1 17.5 20.1 1.4 0.5 41.3 21.0 6.5 4.6 2.2 0.3 3.1 90.1 1.0 5.7 35.6 1.3 17.5 7.8 3.4 9.8 2.5 55.0 30.4 9.2 40.0 1.4 4.8 13.5 1.5 2.0 3.1 8.0 31.4 10.3 22.6 14.7 0.7 5.3 18.7 6.8 0.1 0.6 1.8 6.2 9.7 2.6 4.6 3.4 2.5 60.5 1.6 4.3 0.7 1.0 7.8 5.0 1.3 3.8 2.3 5.7 4.3 3.1 1.6 0.2 7.4 3.8 0.0 12.7 6.7 2.0 10.7 0.5 5.8 8.7 2.3 1.2 2.0 0.9 7.0 1.5 0.0 2.5 6.2 4.3 5.6 9.1 67.8 7.3 7.3 7.3 6.4 29.2 3.5 3.5 0.0 36.5 8.3 3.5 3.4 7.8 13.4 0.0 1.3 2.5 17.9 1.6 5.0 13.3 3.7 5.8 7.2 2.2 3.3 6.8 14.4 0.4 4.9 0.2 0.7 0.4 0.1 5.3 0.2 0.2 0.3 18.7 0.1 3.0 3.7 0.6 1.8 1.5 1.9 0.3 1.5 1.4 0.5 2.2 0.3 1.3 2.0 17.9 25.4 6.9 15.2 93.8 0.2 10.6 45.9 9.4 9.1 21.0 0.0 35.5 373.0 57.8 2.3 5.8 44.1 0.0 96.5 196.1 13.1 33.2 2.3 62.3 36.5 0.0 16.8 8.6 39.4 4.7 4.4 16.7 13.5 4.6 70.8 21.8 73.4 51.8 3.5 383.7 0.9 103.5 9.5 0.4 11.7 123.6 88.9 4.4 78.2 45.7 IMPAD1 "FLJ20421, gPAPP, IMPA3" ENSG00000104331 "Inositol monophosphatase domain containing 1" Q9NX62 8 56957933-56993844 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 560000 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 30.6 33.9 17.8 13.9 23.7 9.6 17.6 23.6 33.1 24.7 17.7 30.9 17.8 11.7 23.2 15.2 17.7 15.6 18.0 25.2 19.9 21.6 21.3 32.6 16.5 10.3 23.6 21.1 16.0 25.2 30.4 20.4 23.3 27.2 28.8 16.2 25.2 28.7 22.5 41.4 13.4 12.3 23.0 21.7 13.0 14.7 19.0 19.5 12.0 24.4 18.1 13.0 17.2 14.9 1.9 2.0 6.1 4.6 6.8 2.4 0.6 17.4 14.5 11.2 11.5 34.5 23.7 15.4 26.6 25.9 19.1 16.7 7.2 12.5 10.9 20.4 28.2 13.6 14.3 13.5 17.9 28.4 15.0 9.7 21.3 10.3 12.9 21.5 13.5 15.2 19.0 18.0 17.1 27.8 17.7 25.3 10.3 9.1 19.9 20.9 9.3 16.4 8.1 8.3 20.0 5.4 11.5 10.1 12.3 19.8 10.4 4.3 12.2 14.9 18.4 15.1 12.3 16.4 9.9 21.1 25.9 14.9 25.5 19.0 20.5 17.1 11.7 35.4 11.3 15.8 2.9 1.9 1.1 2.0 1.2 1.6 1.3 1.3 1.2 1.4 1.9 1.5 2.4 6.1 6.8 4.6 2.0 0.9 0.6 17.8 23.7 23.6 33.1 19.9 21.6 23.6 21.1 27.2 19.5 20.8 18.6 9.0 24.5 48.3 29.9 43.1 25.5 8.1 12.5 45.4 15.7 15.1 5.0 17.1 13.5 27.0 19.0 0.0 23.5 68.2 45.0 43.5 9.2 61.6 24.1 38.1 33.4 38.1 25.6 4.2 23.6 23.8 15.1 5.4 33.4 25.1 24.0 17.5 33.6 16.8 27.4 32.3 38.9 34.6 22.2 52.2 28.3 14.9 16.0 33.9 INO80 "hINO80, Ino80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex subunit" Q9ULG1 15 40978880-41116354 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041484, HPA048601" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nucleoplasm, Nuclear bodies" Cytosol "HPA041484: AB_2677506, HPA048601: " "unprognostic (5.39e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.93e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "prognostic favorable (6.30e-4)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-2)" 14.0 10.6 11.8 13.9 13.4 20.7 13.9 29.5 13.0 12.3 13.2 17.4 11.5 11.3 14.9 13.4 15.1 12.6 12.4 10.6 12.8 7.8 12.1 12.9 14.8 13.4 10.2 10.3 15.4 17.8 18.8 13.3 16.4 12.1 12.5 13.9 13.8 11.9 15.7 23.0 16.4 13.2 13.3 9.5 14.5 12.3 13.9 11.6 18.1 13.3 12.6 15.8 13.9 13.3 5.2 2.3 0.9 2.7 5.7 3.4 1.5 9.2 9.2 8.0 7.8 12.6 10.6 9.3 8.6 14.1 13.1 11.4 11.2 7.8 9.9 7.0 13.1 16.3 18.2 14.7 15.0 13.9 11.4 7.5 12.3 12.7 8.4 12.1 12.1 12.1 10.5 13.9 10.5 27.9 8.7 12.5 10.8 13.7 8.5 8.7 7.7 8.8 8.0 8.4 15.8 10.1 13.6 8.5 7.9 9.9 19.4 10.6 7.3 6.3 13.9 5.8 8.3 7.8 14.7 14.3 10.4 9.5 13.2 13.8 9.4 6.4 16.2 12.2 18.0 8.6 0.9 2.7 0.6 2.7 1.7 3.3 3.2 3.4 3.0 2.3 5.2 3.4 3.2 0.9 5.7 1.2 1.8 2.6 1.5 11.8 13.4 29.5 13.0 12.8 7.8 10.2 10.3 12.1 11.6 8.9 25.5 24.6 15.0 7.6 28.4 14.9 12.7 24.1 23.9 15.7 21.6 11.1 6.6 14.7 1.7 13.7 9.7 0.0 11.5 9.4 10.4 13.3 15.1 8.7 8.7 25.4 12.6 11.6 14.9 1.2 13.6 9.5 6.8 18.0 9.2 11.8 12.4 11.0 14.9 9.4 28.8 6.5 11.3 18.4 22.0 11.2 16.0 12.1 11.9 12.8 INPP1 ENSG00000151689 "Inositol polyphosphate-1-phosphatase" P49441 2 190343470-190371665 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 12 "Early spermatids: 658.4;Late spermatids: 591.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036698, HPA036699" Supported Approved "Centriolar satellite,Cytosol" NA NA 15000 "Centriolar satellite" Cytosol "HPA036698: AB_10672226, HPA036699: AB_2675260" "unprognostic (1.08e-3)" "unprognostic (4.50e-3)" "unprognostic (3.87e-2)" "unprognostic (2.70e-1)" "unprognostic (7.85e-2)" "unprognostic (3.67e-3)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (2.96e-2)" "unprognostic (7.28e-2)" "unprognostic (2.41e-1)" "unprognostic (2.54e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "prognostic favorable (1.12e-5)" "prognostic favorable (5.70e-4)" 14.9 25.8 18.3 9.1 26.5 10.3 32.5 17.4 25.1 15.0 19.8 20.4 11.5 27.4 12.0 10.8 42.7 9.8 20.6 17.7 21.2 17.9 11.0 24.8 19.9 8.8 21.0 16.5 10.0 25.6 32.3 17.0 10.4 18.6 10.0 16.8 12.0 9.9 16.0 13.1 28.3 28.0 15.5 23.6 15.7 13.9 31.4 17.1 4.6 12.9 14.0 15.4 19.2 18.8 1.8 3.5 36.6 3.4 6.2 8.0 1.9 10.9 3.1 6.0 0.0 6.5 14.1 0.1 13.2 17.6 12.4 16.3 11.9 7.0 0.0 15.8 12.6 4.0 15.2 2.4 8.5 15.2 13.5 4.6 8.2 9.7 7.1 13.8 6.1 2.6 9.6 13.1 14.1 8.2 8.9 23.1 0.1 19.6 6.9 21.8 0.0 0.4 5.8 1.8 17.5 17.0 0.2 4.9 0.1 9.6 26.1 8.9 3.3 9.1 0.5 12.8 6.5 0.0 8.8 21.3 7.9 5.6 14.2 7.6 1.3 1.4 0.1 2.5 2.4 6.3 8.1 3.4 36.6 3.0 3.1 2.7 1.4 1.9 2.0 3.5 1.8 1.0 1.5 1.6 6.2 1.8 0.1 8.0 1.9 18.3 26.5 17.4 25.1 21.2 17.9 21.0 16.5 18.6 17.1 3.0 5.6 13.4 129.9 76.7 14.5 19.3 28.1 8.1 20.5 10.4 5.9 5.3 6.6 24.1 658.4 50.2 44.8 0.0 75.1 2.7 22.1 67.5 8.1 17.8 8.6 15.9 29.9 60.2 6.9 591.7 24.7 15.4 25.3 5.4 20.3 68.5 42.2 20.4 22.3 14.6 11.6 25.8 20.2 15.3 7.6 85.1 3.3 17.0 22.6 190.1 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594390 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Bipolar cells: 46.8;Kupffer cells: 37.8;T-cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 9.0 15.0 11.4 13.5 23.1 12.3 7.0 24.0 28.4 7.5 8.5 8.3 3.8 7.7 8.2 5.7 8.4 6.7 11.0 10.8 12.9 7.8 8.1 7.2 13.5 17.0 6.1 19.8 8.3 8.2 12.7 7.0 8.6 17.9 6.8 8.6 16.1 9.3 7.2 13.6 7.3 12.1 10.5 10.4 24.0 8.4 6.4 6.8 17.6 8.4 2.7 13.4 16.8 6.9 0.8 5.9 3.8 5.1 5.8 6.4 1.8 6.4 5.4 10.0 8.0 5.7 6.5 10.0 5.6 5.0 6.0 6.2 6.9 5.7 4.1 6.4 8.2 7.3 6.0 7.1 5.5 4.9 13.7 6.1 4.8 4.9 3.2 5.1 9.1 17.8 5.8 5.2 5.7 5.1 5.1 8.4 23.3 4.4 34.2 4.4 7.8 13.8 8.1 9.4 3.6 5.3 6.0 7.0 26.7 2.9 19.8 6.6 8.6 6.4 5.2 5.1 10.7 2.4 7.3 7.9 7.0 8.9 5.5 3.8 24.3 14.1 2.8 5.7 8.7 6.0 2.0 1.8 3.8 5.5 3.9 6.4 0.8 3.1 3.7 1.9 0.2 4.3 4.9 2.0 5.8 5.1 5.9 1.6 1.8 11.4 23.1 24.0 28.4 12.9 7.8 6.1 19.8 17.9 6.8 6.0 9.6 10.0 4.7 7.1 46.8 10.5 2.5 0.0 10.3 5.2 7.9 7.2 3.3 3.9 12.8 10.1 1.7 0.0 1.3 6.6 7.2 4.6 0.0 3.2 9.0 31.8 5.2 14.7 37.8 5.4 8.6 17.7 10.1 4.6 5.4 9.2 3.8 3.4 11.3 2.2 13.8 6.5 9.0 9.7 11.2 5.4 7.9 39.8 3.5 5.4 INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 163.6;Late spermatids: 196.7;Sertoli cells: 84.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD4 T-cell: 19.2" "Group enriched" "Detected in many" 6 "NK-cells: 9.1;T-cells: 19.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 52.6;SK-MEL-30: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" 15.4 4.7 8.4 8.5 12.5 2.2 21.2 5.1 10.3 28.1 7.1 1.8 5.6 5.0 19.7 18.4 9.1 9.2 8.7 18.4 5.9 6.1 6.1 2.0 9.9 10.8 5.5 8.9 15.4 4.0 2.3 3.8 6.2 4.6 8.3 5.8 1.7 4.9 6.8 10.8 4.7 7.3 10.2 3.1 7.0 7.0 19.6 2.4 8.2 6.5 4.9 7.4 15.8 14.6 0.0 0.0 2.2 0.1 9.1 19.2 3.7 9.3 3.9 2.6 1.2 2.0 1.2 0.5 11.3 13.3 2.9 5.5 1.0 52.6 0.2 3.2 10.1 4.5 14.3 0.0 13.2 6.9 0.0 0.4 2.2 1.5 0.0 0.6 0.4 1.8 2.1 1.8 2.0 7.0 8.8 1.6 0.0 0.0 0.5 6.3 16.7 0.3 0.0 0.1 5.7 2.8 0.1 8.7 0.4 4.0 17.4 0.2 0.2 1.3 4.0 23.4 1.6 12.0 1.6 1.0 6.7 8.2 9.9 0.1 0.1 0.0 0.0 1.5 10.3 17.4 2.2 0.1 0.0 3.3 0.0 6.5 0.0 19.2 8.5 0.0 0.0 13.2 5.7 0.2 9.1 0.0 0.0 9.8 3.7 8.4 12.5 5.1 10.3 5.9 6.1 5.5 8.9 4.6 2.4 0.0 1.1 0.0 9.8 6.0 7.3 36.2 7.6 17.4 9.1 8.7 0.0 1.4 5.0 12.2 163.6 10.8 8.4 0.0 26.9 3.9 4.1 13.4 5.8 0.0 6.2 6.4 8.5 3.7 4.4 196.7 12.7 1.9 69.2 0.0 3.4 0.8 47.4 0.0 6.0 0.8 0.6 84.1 43.7 3.1 2.0 2.3 1.6 16.6 3.4 41.0 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537820-132783480 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 8.4" "Lineage enriched" "Detected in single" 21 "granulocytes: 8.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA Cytosol "Plasma membrane" "HPA012285: AB_1851802" "prognostic unfavorable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 13.6 11.8 10.3 11.3 49.8 5.8 10.3 40.7 20.8 17.4 24.0 10.1 11.5 12.9 25.8 13.9 20.3 15.2 13.6 48.8 9.5 8.5 9.4 7.2 13.8 6.0 9.2 10.4 13.1 11.6 8.9 9.4 19.0 9.1 17.1 11.7 17.1 8.5 16.9 43.7 11.5 14.8 27.9 10.6 8.9 14.8 14.9 16.6 4.2 9.5 12.1 7.8 19.4 22.4 0.3 0.1 8.4 0.2 0.0 0.3 0.6 18.7 7.5 12.6 12.1 19.3 13.6 10.3 19.9 15.3 13.0 8.7 17.7 7.7 1.7 7.7 21.1 8.5 10.7 13.6 8.3 15.7 5.7 7.9 2.7 9.4 24.0 14.0 6.8 6.6 9.2 8.3 8.3 15.9 10.5 9.0 3.6 3.9 10.1 6.9 15.2 1.9 21.9 5.7 11.3 13.4 4.0 8.3 3.0 10.8 10.7 3.0 10.3 9.9 14.7 12.0 12.0 9.5 16.5 7.5 8.4 9.7 11.2 11.6 2.0 9.3 5.8 8.1 4.7 3.6 8.4 0.2 1.1 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.0 1.5 0.0 0.2 0.0 0.3 0.6 10.3 49.8 40.7 20.8 9.5 8.5 9.2 10.4 9.1 16.6 8.9 22.4 1.4 3.6 4.7 10.7 9.0 5.1 2.7 9.1 7.0 0.0 3.3 0.0 5.7 9.4 6.4 18.4 0.0 7.9 3.3 6.2 6.4 8.1 16.0 2.6 7.9 5.8 19.0 6.3 11.2 6.6 3.1 1.7 0.0 9.3 7.8 9.9 11.5 11.0 3.8 4.9 6.5 20.0 5.5 6.6 5.1 2.1 1.9 10.9 5.0 INPP5B ENSG00000204084 "Inositol polyphosphate-5-phosphatase B" P32019 1 37860697-37947057 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028803 Approved Supported Cytosol NA NA Cytosol "HPA028803: AB_10612121" "unprognostic (2.28e-2)" "unprognostic (8.91e-3)" "unprognostic (7.67e-2)" "unprognostic (2.27e-1)" "unprognostic (4.30e-2)" "prognostic favorable (1.11e-4)" "unprognostic (1.67e-2)" "unprognostic (1.52e-2)" "unprognostic (4.75e-2)" "unprognostic (1.85e-1)" "prognostic favorable (5.33e-4)" "unprognostic (8.27e-2)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" 14.5 10.2 11.7 15.9 18.2 22.3 12.8 25.4 16.1 15.3 18.3 21.0 9.4 9.3 19.5 13.7 9.9 15.0 13.7 14.3 12.2 9.0 11.7 16.2 18.7 21.1 23.2 11.4 28.7 11.4 13.1 14.4 14.3 15.9 12.0 13.7 18.9 9.4 16.0 9.7 12.0 13.9 17.5 18.5 19.0 14.7 8.6 21.8 17.4 13.8 4.7 22.3 17.4 13.2 6.7 5.3 19.1 4.7 5.3 9.1 3.8 3.7 2.8 6.7 10.7 8.4 10.8 11.8 4.7 8.3 6.0 8.6 4.4 5.7 14.0 2.2 8.6 3.0 5.2 8.8 3.4 7.8 9.0 3.8 21.3 9.2 2.9 12.2 11.3 31.1 12.6 2.1 6.2 4.0 6.2 7.1 9.4 7.3 18.3 8.1 3.2 9.1 12.0 9.4 5.7 2.2 11.1 13.2 6.6 3.5 3.5 2.6 4.5 5.0 2.4 12.2 9.9 3.0 10.0 7.1 6.0 5.6 5.6 4.3 14.9 7.2 11.3 7.1 10.6 5.1 19.1 2.5 13.2 6.3 2.0 9.1 6.5 4.5 6.1 5.3 6.7 5.8 5.3 3.4 5.3 4.7 4.8 5.6 3.8 11.7 18.2 25.4 16.1 12.2 9.0 23.2 11.4 15.9 21.8 26.8 22.9 10.2 5.0 1.9 15.6 2.4 0.0 5.3 9.1 1.8 23.6 3.4 0.0 1.9 8.1 4.3 3.1 0.0 3.7 12.1 4.3 3.5 8.1 6.4 4.3 22.3 3.4 6.2 6.5 12.4 7.8 6.7 6.8 10.0 4.1 4.5 2.4 3.7 8.5 2.2 20.1 6.5 5.3 4.1 7.5 2.9 3.9 10.7 4.3 3.4 INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" 9 "B-cells: 58.1;Kupffer cells: 48.3;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 15.4;HEL: 31.9;HMC-1: 33.5;hTCEpi: 30.7;NB-4: 29.9;THP-1: 21.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016300, HPA070455" Enhanced Approved Cytosol No No Cytosol "CAB016300: AB_628250, HPA070455: AB_2686267" "unprognostic (5.29e-2)" "unprognostic (2.05e-3)" "unprognostic (1.99e-2)" "unprognostic (6.71e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.74e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (6.54e-2)" 7.1 3.1 7.2 33.0 10.7 24.6 4.7 1.7 6.9 3.6 3.7 12.5 0.7 3.5 4.1 2.9 3.3 3.3 6.7 3.2 6.6 9.1 5.1 3.3 8.0 26.1 8.8 2.6 1.9 2.1 1.6 3.4 7.4 7.6 4.5 4.5 3.3 18.8 3.0 1.9 3.4 15.8 3.4 17.6 40.9 4.1 2.4 9.5 16.7 3.1 3.4 32.3 6.2 3.5 14.5 12.0 10.5 18.2 11.9 16.7 14.0 0.0 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 5.1 0.0 31.9 0.0 3.0 0.2 9.6 33.5 0.6 30.7 0.1 3.4 0.1 4.4 0.9 0.1 2.8 0.1 0.0 4.4 29.9 1.0 0.0 0.0 9.3 0.0 2.2 0.0 1.8 0.0 0.0 0.0 0.6 0.0 4.1 0.0 21.4 3.6 0.0 0.5 0.0 0.0 0.0 1.7 9.2 0.0 12.4 0.0 9.8 9.8 10.5 16.7 15.8 11.4 14.5 7.5 12.3 12.0 13.9 6.3 8.8 9.9 11.9 18.2 6.0 10.2 14.0 7.2 10.7 1.7 6.9 6.6 9.1 8.8 2.6 7.6 9.5 3.0 25.7 58.1 1.2 1.4 0.1 3.2 2.5 4.0 4.5 3.5 0.0 0.4 0.0 0.3 12.8 17.5 0.0 0.0 0.4 0.6 1.0 0.4 14.0 1.3 24.6 0.0 0.0 13.5 48.3 10.6 0.0 20.7 0.0 13.6 0.2 0.0 0.2 0.9 1.1 0.3 0.0 0.0 1.2 0.4 0.7 1.0 0.9 51.0 0.4 1.0 INPP5E "CORS1, JBTS1, pharbin, PPI5PIV" ENSG00000148384 "Inositol polyphosphate-5-phosphatase E" Q9NRR6 9 136428619-136439823 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Ciliopathy, Disease mutation, Joubert syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065758 Approved Supported "Nucleoplasm,Golgi apparatus,Focal adhesion sites" NA NA "Golgi apparatus, Focal adhesion sites" Nucleoplasm "HPA065758: AB_2685554" "unprognostic (1.99e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-2)" "unprognostic (4.00e-1)" "unprognostic (6.92e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-1)" "unprognostic (5.81e-2)" "unprognostic (2.65e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.03e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-1)" "unprognostic (5.48e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" 14.3 11.2 14.9 15.3 10.4 8.9 19.2 19.9 19.1 10.5 10.7 11.5 11.1 10.3 13.1 10.1 8.4 17.2 9.4 11.9 12.6 12.0 10.2 9.0 10.1 13.5 8.4 12.3 14.7 11.6 11.4 12.3 9.8 13.2 9.9 5.2 11.0 14.4 12.9 11.6 18.2 10.7 10.7 6.6 19.4 8.6 15.2 10.3 8.5 12.5 6.2 10.7 8.8 19.3 2.6 1.0 1.9 0.5 0.0 2.4 0.6 6.2 7.2 8.5 8.4 4.3 5.6 10.5 7.5 4.4 5.8 3.7 7.4 4.4 7.8 7.7 6.3 8.3 17.5 3.7 5.1 2.2 24.3 14.7 5.2 12.4 4.9 7.3 6.1 8.5 6.0 4.8 6.4 5.7 6.9 5.6 10.0 8.8 7.2 4.9 10.3 7.8 13.4 5.5 3.9 12.0 14.3 6.5 5.8 5.2 6.1 8.9 8.0 7.2 6.8 5.2 6.1 10.9 9.1 8.0 17.9 6.7 7.2 13.0 7.8 6.3 3.3 9.2 5.4 6.5 0.0 0.5 1.9 2.0 0.0 1.3 2.6 2.3 1.5 0.5 1.7 0.8 1.6 0.4 0.0 0.3 1.0 2.4 0.6 14.9 10.4 19.9 19.1 12.6 12.0 8.4 12.3 13.2 10.3 3.0 5.8 2.9 1.5 4.8 7.1 4.1 7.6 6.7 3.4 3.5 2.0 2.0 1.7 4.5 0.3 5.8 2.8 0.0 4.8 2.0 3.9 2.0 9.2 3.0 2.6 14.3 5.8 2.5 3.8 0.7 6.9 3.5 5.0 4.6 2.9 8.5 5.3 0.0 5.3 2.2 11.4 0.0 4.8 9.8 7.8 4.3 0.7 4.3 4.3 1.6 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726097-119829278 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 30.5;SH-SY5Y: 24.2;SK-MEL-30: 46.0;SuSa: 63.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 4.6 12.3 17.5 5.9 50.4 3.2 5.7 37.0 52.9 10.9 5.0 5.5 2.2 3.1 11.8 18.0 4.5 4.2 5.5 4.1 24.6 53.1 7.3 2.0 4.2 7.6 23.7 29.1 9.8 4.6 8.9 34.0 8.2 69.7 8.3 6.1 3.4 7.1 8.4 7.5 10.4 3.8 10.8 19.2 4.1 3.8 10.1 7.3 1.4 8.4 1.4 9.3 5.3 4.5 12.2 7.4 1.5 4.5 3.8 6.7 2.2 3.9 2.7 30.5 4.4 3.3 3.4 2.7 5.5 3.0 2.6 2.6 4.0 5.0 2.5 2.1 6.9 3.6 4.4 3.3 3.2 4.0 1.6 3.0 1.7 1.4 4.1 4.6 1.1 5.6 4.1 3.0 5.2 5.2 5.4 8.8 2.0 1.5 4.1 6.2 2.2 1.5 4.6 2.9 3.6 3.5 2.1 5.4 0.6 4.4 2.0 2.2 24.2 6.1 1.9 46.0 63.8 1.3 1.2 5.8 2.6 3.4 3.4 5.3 4.6 2.0 1.1 3.3 3.9 10.7 1.1 4.0 1.5 1.3 3.5 1.6 8.1 2.8 1.9 7.4 12.2 3.2 1.4 1.0 3.8 4.5 1.8 6.7 2.2 17.5 50.4 37.0 50.5 24.6 53.1 23.7 29.1 69.7 7.3 6.0 4.5 10.0 9.8 8.0 24.8 5.3 0.0 2.7 5.7 12.2 15.7 7.7 10.0 3.1 28.7 7.4 6.4 0.0 3.9 7.2 6.7 8.4 2.3 2.8 8.6 39.7 1.2 4.9 5.7 18.7 4.9 11.5 18.6 21.6 5.8 18.8 5.5 5.5 3.5 16.7 21.0 6.5 7.5 10.3 40.3 9.2 11.1 4.3 6.0 10.2 INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134696 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 65.2;thyroid gland: 71.2" "Cell type enhanced" "Detected in many" 11 "Collecting duct cells: 33.2;Enterocytes: 31.9;Muller glia cells: 20.3" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 2.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.4" "Cell line enhanced" "Detected in many" "HL-60: 12.3;SK-BR-3: 26.8;T-47d: 16.9;U-698: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034539 Approved Nucleoli,Cytosol NA NA Cytosol Nucleoli "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" 0.8 0.9 4.6 0.8 6.3 0.5 3.7 27.4 13.4 1.5 6.4 0.8 16.7 7.9 1.3 0.8 1.0 1.0 1.0 9.5 7.4 2.0 9.5 0.5 1.5 0.7 2.3 4.6 0.8 5.3 65.2 3.7 0.5 5.5 3.5 2.2 5.6 15.5 19.2 1.6 1.7 21.7 1.2 0.9 0.6 3.8 1.6 1.1 0.0 71.2 0.0 0.7 1.1 0.9 0.3 2.4 0.0 0.4 0.0 0.0 0.2 1.3 1.3 0.8 1.5 0.2 0.2 0.7 0.5 0.5 2.7 2.6 0.8 0.8 0.0 0.6 0.2 0.3 1.6 1.6 0.7 1.1 0.0 4.3 0.0 5.6 0.2 0.5 12.3 0.1 0.1 0.8 2.2 0.2 1.8 0.1 0.0 1.1 1.9 0.0 4.1 0.1 0.0 1.5 1.7 0.2 0.0 0.3 2.9 1.1 1.6 6.5 4.9 1.0 26.8 0.3 0.7 16.9 1.0 0.0 0.1 4.9 0.5 0.3 0.0 2.1 11.6 0.4 0.0 2.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.2 4.6 6.3 27.4 13.4 7.4 2.0 2.3 4.6 5.5 1.1 0.0 2.6 0.0 2.3 0.8 7.9 4.8 0.0 0.0 1.2 33.2 0.0 0.0 10.0 1.2 0.3 0.0 31.9 0.0 1.9 0.1 0.2 3.7 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 5.0 20.3 1.0 10.5 0.0 0.6 2.3 0.0 0.3 1.7 0.9 1.1 0.1 0.0 6.8 0.9 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494571-1516888 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 114.9" "Cell type enhanced" "Detected in many" 11 "Late spermatids: 261.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (7.47e-2)" "prognostic favorable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favorable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 27.9 10.5 12.7 13.8 13.5 25.9 37.0 14.9 17.7 13.4 13.4 14.9 9.8 9.1 12.8 12.2 12.0 10.4 12.9 17.5 12.8 12.6 11.6 10.5 20.8 14.3 12.8 12.0 14.3 18.9 12.0 10.8 15.9 21.2 13.5 11.4 114.9 12.9 12.2 26.4 22.3 13.9 10.9 10.7 16.2 12.8 20.8 11.3 22.1 27.3 13.8 16.4 12.5 14.1 12.1 16.5 36.4 27.0 17.0 30.8 24.6 9.5 13.2 5.4 10.4 14.1 7.9 8.1 8.0 13.5 9.1 11.6 8.2 5.7 8.5 15.4 12.2 7.5 12.5 13.0 5.2 9.3 22.0 21.8 5.3 10.1 3.2 17.9 5.0 10.3 9.3 13.8 9.1 9.0 5.8 14.4 14.5 5.7 15.3 6.0 6.8 15.1 4.1 2.3 14.3 9.0 11.6 4.3 8.0 7.3 5.9 4.3 10.9 6.3 12.3 14.3 8.4 10.4 4.1 10.2 8.0 8.2 11.5 10.3 8.1 13.5 4.5 9.0 5.2 10.0 36.4 19.9 31.9 22.2 18.7 18.2 12.1 20.7 22.4 16.5 11.3 17.7 18.9 33.3 17.0 27.0 11.9 30.8 24.6 12.7 13.5 14.9 17.7 12.8 12.6 12.8 12.0 21.2 11.3 29.8 13.1 9.5 13.9 26.7 7.5 31.5 5.1 5.3 7.9 22.7 2.0 11.5 11.6 15.2 90.2 27.4 20.9 0.0 21.2 13.3 15.4 14.1 19.6 8.9 10.7 19.1 16.7 21.5 19.1 261.4 10.6 16.0 30.4 48.7 17.0 20.3 21.3 21.0 7.1 9.0 7.6 19.4 16.4 31.6 16.7 26.5 26.0 36.3 11.0 14.4 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239105 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA Cytosol "Golgi apparatus" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 20.9 23.7 22.2 20.4 19.5 25.1 18.6 11.1 18.9 25.2 32.0 22.7 28.8 19.8 24.7 18.4 17.4 24.3 29.6 29.5 24.1 10.3 23.9 17.1 24.9 19.0 27.6 10.4 30.1 22.7 21.6 26.9 31.9 20.4 28.7 13.5 30.7 27.5 24.2 60.0 17.7 23.0 34.7 27.5 28.3 24.5 11.8 24.3 16.0 29.1 19.3 18.3 25.0 18.1 2.6 5.2 7.0 7.6 4.2 4.5 3.3 6.5 14.0 16.8 11.4 8.3 9.9 30.0 30.2 14.1 18.9 12.1 19.1 16.5 18.6 30.8 23.0 13.5 24.9 13.8 8.5 6.5 24.1 14.3 19.3 70.9 7.0 16.3 12.7 43.3 14.0 9.0 18.3 7.3 23.5 10.1 6.9 13.6 8.0 10.3 17.6 9.4 51.6 17.2 4.6 21.9 44.5 38.2 4.1 22.0 11.0 8.2 11.9 32.4 19.6 42.1 8.9 20.7 24.2 17.2 20.3 23.8 31.1 9.8 23.2 3.8 18.2 5.7 12.1 11.0 5.2 7.6 7.0 4.5 4.4 3.7 2.2 3.7 3.0 5.2 2.6 2.7 3.7 5.2 4.2 7.0 3.9 3.3 3.3 22.2 19.5 11.1 18.9 24.1 10.3 27.6 10.4 20.4 24.3 3.0 13.8 2.4 4.6 6.4 1.2 11.2 5.1 5.3 10.3 12.2 25.5 20.7 1.7 10.7 1.1 6.3 16.0 0.0 10.6 12.5 9.8 6.8 7.0 8.6 18.9 9.5 21.8 10.4 26.9 1.5 9.2 18.1 10.1 3.6 15.4 14.3 13.4 17.5 13.1 12.5 17.2 6.5 9.2 1.2 4.1 4.3 27.1 6.7 17.5 5.2 ISG20 "CD25, HEM45" ENSG00000172183 "Interferon stimulated exonuclease gene 20" Q96AZ6 15 88636153-88656483 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 116.8;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" 5 "B-cells: 305.7;monocytes: 313.8;Urothelial cells: 376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 36.6;Karpas-707: 21.7;SK-MEL-30: 121.9;U-698: 21.8" "Not detected" "Not detected" NA NA "unprognostic (2.55e-3)" "unprognostic (1.19e-3)" "unprognostic (2.00e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (4.54e-2)" "unprognostic (1.35e-3)" "prognostic favorable (1.85e-5)" "unprognostic (5.60e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.86e-8)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "unprognostic (3.39e-1)" "unprognostic (1.58e-2)" 8.4 2.4 2.2 39.6 3.6 12.1 7.3 0.8 3.1 4.1 18.3 1.9 8.3 25.9 2.7 8.2 9.9 3.9 36.6 4.9 2.4 2.6 6.1 9.9 26.0 56.6 3.2 1.8 6.8 6.4 0.2 10.1 4.6 3.2 6.0 3.0 2.2 13.2 8.1 4.1 3.4 39.4 1.2 3.6 53.8 21.9 2.5 1.8 29.1 14.5 6.1 41.4 10.7 4.2 99.2 12.3 116.8 5.1 31.0 104.4 29.7 1.6 2.5 0.0 0.0 0.0 0.0 0.4 0.0 1.1 7.5 10.4 0.8 3.6 36.6 1.9 0.1 3.5 0.5 0.1 0.8 0.2 11.5 0.1 0.1 1.2 1.5 5.0 0.0 0.0 0.7 1.4 2.6 1.7 0.1 1.2 2.6 0.1 21.7 0.0 2.6 0.1 0.2 0.3 5.8 5.5 1.4 0.1 6.8 0.6 0.3 0.1 0.1 0.3 14.5 121.9 0.0 0.4 0.8 1.5 0.2 0.8 0.0 0.5 15.4 4.1 21.8 0.3 0.5 1.5 8.4 3.0 6.2 27.7 5.1 36.6 94.6 47.9 39.7 2.6 99.2 35.5 37.2 116.8 31.0 3.8 12.3 104.4 29.7 2.2 3.6 0.8 3.1 2.4 2.6 3.2 1.8 3.2 1.8 44.7 47.2 305.7 100.8 158.8 0.0 1.2 50.9 65.6 50.0 3.5 0.0 1.5 1.7 54.2 12.1 28.6 92.1 116.8 133.1 66.9 47.5 249.9 7.0 10.4 8.0 0.0 36.0 14.1 25.6 3.3 2.0 43.4 214.2 313.8 83.6 0.0 202.6 80.7 1.8 5.5 0.1 25.8 27.8 0.9 2.1 250.9 43.5 278.6 6.2 376.0 ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022824, HPA073963" Approved Supported Nucleoplasm,Cytosol NA NA 69000 "Nucleoplasm, Cytosol" "HPA022824: AB_1851960, HPA073963: " "unprognostic (1.58e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-1)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (1.53e-2)" "prognostic unfavorable (2.54e-5)" "unprognostic (1.11e-2)" "unprognostic (1.68e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-1)" "unprognostic (1.94e-2)" "unprognostic (8.34e-2)" "unprognostic (3.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-1)" 17.7 27.5 18.6 24.7 21.2 20.4 17.7 10.2 22.7 21.3 21.4 18.3 20.6 22.9 18.1 17.3 31.0 26.6 19.6 25.9 18.1 13.5 22.9 20.3 22.7 30.6 20.5 24.1 16.5 43.8 17.6 10.2 17.0 16.2 14.6 16.8 13.2 19.9 21.5 19.5 23.4 19.0 16.3 16.3 20.6 19.3 16.7 19.5 15.2 24.9 29.0 24.1 14.6 17.7 19.3 30.7 11.3 31.0 24.7 24.1 18.2 32.7 25.9 12.8 13.3 8.5 12.6 8.5 14.9 20.7 19.6 17.2 20.7 30.5 14.1 13.6 13.6 19.2 28.5 17.6 22.3 13.7 9.2 26.3 35.3 10.7 31.4 16.1 15.1 12.0 12.0 17.1 18.4 11.5 8.1 14.9 11.4 24.2 9.7 17.5 15.0 17.8 43.9 21.4 37.0 26.2 17.1 17.8 37.0 26.8 10.4 19.4 22.9 11.7 41.1 27.3 5.9 17.1 25.2 10.4 22.0 12.3 14.4 31.4 14.5 18.2 26.7 10.2 28.0 23.9 11.3 25.7 8.8 20.7 31.0 18.0 19.3 18.9 21.8 30.7 17.8 14.2 17.2 1.4 24.7 21.9 28.3 24.1 18.2 18.6 21.2 10.2 22.7 18.1 13.5 20.5 24.1 16.2 19.5 20.8 43.1 32.8 43.8 35.6 18.3 8.0 40.8 26.8 37.5 41.8 13.7 62.7 49.7 88.7 2.3 18.6 41.6 0.0 90.9 108.9 44.0 43.6 41.5 32.1 103.0 4.8 26.4 29.4 43.0 2.3 28.7 50.7 38.8 123.6 48.5 17.1 82.5 52.6 20.8 63.4 20.3 19.4 36.4 14.6 19.4 43.0 47.0 46.3 66.6 52.1 JOSD1 KIAA0063 ENSG00000100221 "Josephin domain containing 1" Q15040 22 38685543-38701556 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001168 Uncertain NA NA "HPA001168: AB_1079162" "unprognostic (6.50e-2)" "unprognostic (1.06e-2)" "unprognostic (3.42e-3)" "unprognostic (5.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-3)" "unprognostic (2.46e-1)" "unprognostic (1.83e-3)" "unprognostic (1.06e-1)" "unprognostic (4.41e-1)" "unprognostic (2.88e-2)" "unprognostic (4.41e-1)" 20.4 16.8 17.5 19.9 18.3 55.8 26.0 23.2 30.5 19.0 34.6 11.0 16.2 19.9 19.1 20.1 20.8 18.6 29.9 20.8 16.9 14.2 13.1 16.0 22.6 18.8 14.2 20.7 35.5 18.8 14.7 19.5 16.5 13.9 16.2 28.8 12.5 15.0 27.7 16.5 17.2 45.2 20.8 15.0 16.5 16.8 13.7 8.1 16.4 16.1 20.9 17.2 23.6 18.6 3.3 2.5 7.2 5.6 4.1 7.6 2.5 26.4 9.5 14.0 18.0 17.9 22.0 10.6 20.4 24.4 26.6 27.9 15.7 13.5 25.4 10.6 20.3 17.7 17.1 19.3 18.1 21.5 27.1 12.8 13.4 22.8 13.4 30.6 24.1 13.2 19.0 27.0 25.0 43.1 23.4 31.3 16.1 12.0 27.0 19.5 11.2 10.4 9.9 5.3 16.0 10.8 18.8 20.5 10.6 14.4 13.7 12.9 6.9 23.4 11.6 20.9 12.2 11.6 7.0 27.2 15.9 19.4 20.4 12.3 29.9 25.9 20.7 21.1 12.9 14.7 1.8 3.5 3.7 5.3 5.6 3.8 3.3 4.5 6.9 2.5 3.2 4.9 7.6 7.2 4.1 3.0 2.1 5.8 2.5 17.5 18.3 23.2 30.5 16.9 14.2 14.2 20.7 13.9 8.1 23.8 17.9 22.7 61.3 41.2 28.2 15.6 43.3 16.0 12.5 34.9 21.6 8.8 11.6 30.0 2.9 24.5 63.9 0.0 33.6 12.0 20.6 61.4 16.1 20.2 20.5 17.5 22.4 25.8 27.0 3.6 11.8 33.6 15.1 34.3 47.0 20.3 48.9 31.6 13.1 11.6 21.6 12.9 17.4 14.4 28.0 45.0 10.8 24.5 28.3 87.3 JOSD2 SBBI54 ENSG00000161677 "Josephin domain containing 2" Q8TAC2 19 50505998-50511353 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (8.77e-2)" "unprognostic (3.09e-2)" "unprognostic (2.59e-1)" "unprognostic (1.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (3.63e-2)" "unprognostic (2.41e-1)" "unprognostic (5.68e-2)" "unprognostic (1.75e-2)" "unprognostic (6.49e-2)" "unprognostic (2.42e-3)" "unprognostic (8.05e-2)" "unprognostic (2.04e-1)" "unprognostic (6.05e-2)" "unprognostic (9.34e-2)" 20.7 14.1 18.0 14.6 19.6 16.8 21.7 7.5 18.6 11.2 16.0 18.9 11.5 24.0 13.0 12.3 15.4 11.0 15.5 19.1 19.3 14.4 12.4 25.4 13.1 21.6 22.6 11.6 11.0 13.6 8.8 9.8 12.5 19.5 10.4 5.1 7.5 21.6 15.0 28.3 21.0 20.8 8.9 30.4 14.7 24.8 8.8 16.7 9.8 23.7 15.5 6.7 11.6 16.4 8.7 26.2 33.6 36.9 10.5 18.7 16.5 15.6 28.1 0.1 8.3 9.4 11.2 5.1 19.2 7.4 5.6 5.8 4.7 12.2 4.6 11.7 7.4 6.9 10.7 0.8 9.0 1.5 21.2 11.3 4.7 5.2 2.3 12.0 1.3 16.9 12.1 8.0 3.7 2.8 7.2 5.1 5.3 5.8 12.3 5.8 12.0 5.4 6.1 1.9 10.6 27.2 1.5 12.8 8.9 5.4 15.1 4.7 12.2 5.6 14.6 15.9 0.7 11.5 8.3 11.0 9.5 11.3 12.0 10.9 12.9 10.2 1.5 27.0 5.9 18.3 16.5 36.9 33.6 17.5 33.8 14.7 8.7 16.8 17.8 26.2 8.6 12.3 13.5 6.2 10.5 23.7 18.9 18.7 16.5 18.0 19.6 7.5 18.6 19.3 14.4 22.6 11.6 19.5 16.7 6.0 1.7 14.9 35.9 27.5 9.8 2.5 40.8 8.1 0.0 31.4 0.0 34.8 56.3 77.8 10.1 24.8 134.0 0.0 76.1 82.0 46.3 25.7 5.7 58.7 84.4 15.9 16.1 46.6 72.5 27.7 82.6 63.3 74.2 108.2 55.0 26.4 101.5 105.2 91.9 66.9 9.3 51.8 45.7 23.2 18.1 40.1 34.6 33.0 42.0 48.9 KATNA1 ENSG00000186625 "Katanin catalytic subunit A1" O75449 6 149594873-149648972 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 12 "Early spermatids: 312.3;Late spermatids: 142.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036207 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Centriolar satellite" Nucleoplasm "HPA036207: AB_10672238" "unprognostic (1.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.95e-2)" "unprognostic (3.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.57e-7)" "unprognostic (9.78e-2)" "unprognostic (8.89e-2)" "unprognostic (7.40e-2)" "unprognostic (2.70e-2)" "unprognostic (4.50e-2)" "unprognostic (3.92e-2)" "unprognostic (2.10e-1)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (8.85e-2)" 12.5 7.8 9.3 11.9 9.8 14.2 11.7 13.0 9.5 13.8 12.1 15.0 6.0 7.6 15.3 10.3 12.5 10.9 10.1 11.3 9.1 6.7 13.7 8.4 10.8 11.8 10.4 7.9 18.7 9.6 5.7 12.1 11.0 15.0 12.7 9.5 17.5 10.1 10.5 21.2 12.0 10.8 12.4 8.9 12.2 10.4 36.7 12.0 22.5 13.9 10.3 14.0 15.1 12.7 19.6 19.4 23.5 20.8 12.7 24.2 14.9 11.5 4.1 9.5 20.7 11.5 18.4 14.7 14.5 12.3 15.3 20.3 9.9 6.1 16.1 8.4 14.4 11.1 9.1 18.6 9.5 20.0 14.7 15.7 21.4 8.9 13.7 15.9 29.9 8.1 11.6 11.3 17.5 13.9 14.2 14.0 21.7 22.1 11.8 13.5 16.0 20.5 19.5 9.3 12.9 7.0 14.1 17.3 7.8 10.9 6.5 7.7 10.9 26.4 7.6 10.1 13.9 7.8 29.2 12.0 8.0 12.2 21.0 16.7 11.0 10.1 22.1 10.5 21.3 13.0 23.5 15.2 21.0 19.9 20.8 17.5 19.6 20.2 20.0 19.4 14.2 17.2 17.3 7.0 12.7 18.0 16.7 24.2 14.9 9.3 9.8 13.0 9.5 9.1 6.7 10.4 7.9 15.0 12.0 14.9 9.9 13.7 31.3 26.1 8.6 15.9 10.2 24.1 13.6 14.0 27.5 18.4 14.9 16.5 312.3 15.5 9.7 23.3 10.9 15.9 23.8 16.3 19.7 6.6 15.3 12.7 5.8 10.4 11.8 142.0 19.5 18.0 10.1 22.6 8.4 10.9 12.0 10.5 15.6 16.6 34.9 6.5 18.9 100.5 54.7 25.1 21.4 17.5 8.9 15.2 KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307484 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 30.6" "Low region specificity" "Detected in all" HPA046205 Uncertain Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA046205: AB_10965325" "unprognostic (3.34e-1)" "unprognostic (6.44e-3)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (2.84e-2)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.41e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.83e-3)" 11.0 5.7 12.2 6.4 12.5 7.6 12.0 11.0 14.4 14.1 11.4 10.4 4.6 2.2 12.7 4.2 8.1 6.6 5.4 22.6 8.5 9.8 5.9 5.4 6.7 8.2 10.3 14.9 6.3 2.9 3.2 11.9 4.2 11.9 6.7 5.9 4.1 3.5 8.5 7.1 3.8 4.2 19.7 10.8 4.5 4.7 25.1 7.8 12.0 4.4 3.3 9.1 7.7 7.9 5.2 6.9 3.4 1.0 9.5 7.1 1.4 5.5 4.6 8.1 4.3 6.2 13.2 0.2 23.0 7.4 12.3 9.7 0.9 5.6 8.9 2.7 30.6 15.5 1.5 5.7 5.9 18.8 7.7 2.1 6.4 5.7 2.1 3.3 3.1 4.3 5.1 3.0 13.8 3.4 11.6 12.9 5.0 3.4 3.9 15.0 1.1 7.0 2.9 3.5 0.1 3.0 7.9 9.6 0.9 4.4 0.4 3.4 7.1 6.1 1.2 4.3 7.1 2.0 1.9 11.7 10.9 16.6 5.9 9.2 2.1 3.8 12.3 4.3 3.1 15.6 1.9 0.9 3.4 5.8 0.5 2.9 2.6 4.6 5.8 2.3 5.2 1.1 2.6 0.3 9.5 1.0 6.9 7.1 1.4 12.2 12.5 11.0 14.4 8.5 9.8 10.3 14.9 11.9 7.8 8.9 2.6 1.9 3.5 5.3 9.0 35.3 2.5 16.0 2.3 5.2 25.5 0.2 3.3 5.4 107.1 6.4 0.0 0.0 1.3 0.7 9.4 1.6 9.3 9.0 2.8 20.6 9.8 6.7 2.1 42.6 8.3 3.4 16.9 35.1 0.5 8.5 4.5 0.0 4.9 5.7 17.6 6.5 11.2 41.6 21.5 5.0 0.2 7.5 0.6 1.3 KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47102243 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 30.3;testis: 33.2" "Group enriched" "Detected in many" 4 "Ciliated cells: 46.8;Early spermatids: 59.9;Late spermatids: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040712, HPA042029" Approved Approved "Nucleoplasm,Intermediate filaments" No No "Nucleoplasm, Intermediate filaments" "HPA040712: AB_2677092, HPA042029: AB_2677807" "unprognostic (3.40e-1)" "unprognostic (7.75e-2)" "unprognostic (9.00e-3)" "unprognostic (9.28e-2)" "unprognostic (1.74e-2)" "unprognostic (6.55e-3)" "unprognostic (6.97e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (5.36e-2)" "unprognostic (9.52e-6)" "unprognostic (1.28e-1)" "prognostic favorable (1.24e-7)" "unprognostic (1.64e-1)" "unprognostic (7.14e-4)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" 5.5 2.9 8.2 4.1 9.7 2.8 7.1 4.0 7.5 2.5 2.4 11.3 2.5 1.8 2.8 7.1 2.7 8.6 5.1 4.3 8.1 7.6 9.5 5.2 4.6 3.4 9.6 6.2 3.1 3.3 30.3 7.0 2.2 9.0 3.4 3.1 6.4 3.4 3.7 6.0 8.0 1.5 2.3 8.7 3.3 2.0 33.2 6.3 2.4 15.5 1.1 3.0 2.3 2.5 3.1 0.6 2.7 1.3 0.8 1.5 0.3 1.9 4.3 2.4 15.0 4.9 5.9 1.1 1.8 1.6 1.5 1.9 0.2 5.1 19.8 1.5 2.8 1.9 0.6 4.7 0.5 1.1 2.0 2.5 0.8 1.3 0.3 2.0 1.2 1.9 12.2 1.8 2.5 0.6 3.4 0.5 9.1 0.7 1.6 8.5 1.9 1.2 2.6 5.4 2.5 2.7 5.5 1.1 0.0 4.7 0.4 5.4 6.0 1.9 0.4 0.6 8.8 11.4 11.0 1.0 5.0 0.5 2.0 1.2 1.3 1.0 13.3 2.7 12.5 9.6 1.7 0.7 0.5 1.1 1.3 0.9 2.2 0.9 0.5 0.3 3.1 1.5 1.4 2.7 0.8 0.9 0.6 0.2 0.3 8.2 9.7 4.0 7.5 8.1 7.6 9.6 6.2 9.0 6.3 0.0 1.4 0.0 2.6 1.3 10.4 2.2 0.0 46.8 6.8 3.5 5.9 0.0 11.6 0.4 59.9 1.4 0.8 0.0 0.2 0.0 1.5 1.2 0.0 3.9 2.8 11.1 0.0 3.1 1.0 47.0 1.4 0.6 3.3 1.0 0.3 2.4 0.2 0.0 2.1 5.2 2.1 0.0 0.8 11.2 4.3 1.0 0.1 0.0 1.5 1.4 KIAA0391 "MRPP3, PRORP" ENSG00000100890 KIAA0391 O15091 14 35121846-35277614 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA020459 Approved Supported Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "HPA020459: AB_2670449" "unprognostic (6.44e-3)" "unprognostic (8.10e-2)" "unprognostic (7.71e-3)" "unprognostic (4.90e-2)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" "unprognostic (8.67e-2)" "unprognostic (1.94e-2)" "unprognostic (3.25e-4)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (9.67e-5)" "unprognostic (2.56e-1)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (6.65e-2)" 13.9 26.1 18.8 17.6 20.1 12.5 17.5 23.1 21.9 17.4 22.4 20.6 15.6 16.6 13.0 19.4 26.1 14.7 13.2 16.7 17.6 16.3 31.1 29.5 20.9 29.5 20.2 17.7 10.8 16.5 29.8 27.4 13.4 19.2 14.1 24.9 15.8 18.0 21.8 22.2 23.0 16.5 15.0 23.0 18.7 15.8 17.1 20.9 31.2 18.9 21.3 24.8 18.2 16.0 10.0 9.7 10.9 5.4 12.1 25.5 12.4 22.8 18.3 12.7 16.8 13.9 16.5 11.2 15.4 13.8 19.7 17.1 17.3 14.2 25.1 20.1 14.6 5.6 17.8 23.3 26.6 22.3 19.7 7.2 11.3 14.1 36.9 14.4 13.9 12.4 17.6 20.5 18.6 17.2 17.0 28.5 21.6 18.2 7.3 24.0 25.9 21.0 15.3 13.6 19.8 18.1 20.2 21.1 14.5 27.7 23.4 11.8 13.4 19.9 22.1 12.8 17.1 32.2 11.5 21.6 15.2 13.7 11.7 13.2 8.0 18.6 26.3 7.7 15.1 15.9 10.9 5.4 3.4 15.4 5.2 22.4 10.0 23.8 16.6 7.2 7.0 21.2 15.6 6.3 12.1 4.3 9.7 25.5 12.4 18.8 20.1 23.1 21.9 17.6 16.3 20.2 17.7 19.2 20.9 3.0 1.3 1.3 0.5 0.0 1.3 1.5 0.0 1.4 2.3 0.0 0.0 0.8 1.7 1.0 0.0 1.0 1.4 0.0 0.8 0.5 0.8 1.0 2.3 1.6 1.0 0.0 0.0 1.8 0.8 0.0 0.6 0.8 0.0 0.0 0.9 1.2 1.5 0.0 0.4 1.4 1.5 0.0 0.3 0.5 1.1 0.0 0.6 0.0 1.6 0.9 KL ENSG00000133116 Klotho Q9UEF7 13 33016433-33066145 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 64.3;parathyroid gland: 76.9;placenta: 25.5" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 99.7" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Region enhanced" "Detected in some" "pons and medulla: 11.6" "Cell type enhanced" "Detected in single" "classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HMC-1: 5.1;SK-BR-3: 9.6" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 510000 "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 4.8 0.6 0.8 0.9 4.3 0.1 7.4 0.0 0.8 0.7 2.1 3.3 0.2 1.0 1.0 3.2 0.8 0.7 0.9 0.9 2.4 0.8 64.3 0.2 10.4 0.9 0.5 0.3 0.4 1.6 76.9 0.3 25.5 11.6 3.3 0.4 0.3 0.7 1.0 0.9 0.4 3.2 0.7 0.4 3.1 1.9 0.6 0.3 0.0 1.4 1.3 0.3 1.5 1.1 0.0 0.0 0.0 1.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.8 4.3 0.0 0.8 2.4 0.8 0.5 0.3 11.6 0.3 0.0 0.3 0.0 0.1 0.1 0.0 0.8 0.0 1.4 1.2 12.2 0.0 0.1 5.0 0.0 1.7 1.8 0.9 0.0 0.0 0.1 0.7 4.4 0.0 0.0 2.1 0.0 15.6 0.0 0.8 0.0 0.3 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.4 99.7 0.0 0.0 0.3 0.5 0.2 0.1 0.1 0.0 0.6 0.1 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819148-50823787 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "pancreas: 742.6;salivary gland: 473.0" "Cell type enhanced" "Detected in many" 19 "Exocrine glandular cells: 663.7;Mucus-secreting cells: 890.7;Pancreatic endocrine cells: 205.3" "Group enriched" "Detected in many" 6 "colorectal cancer: 20.0;pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 10.9;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 14 "B-cells: 10.9" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 29.2" "Secreted to digestive system" NA NA 4300000 "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.2 2.5 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.8 0.1 0.1 0.1 0.1 0.1 0.1 742.6 0.0 0.1 0.1 0.1 0.2 1.9 0.1 473.0 0.1 0.1 1.8 0.6 0.1 0.1 0.3 0.1 0.1 0.1 0.1 1.2 0.2 0.2 0.1 0.1 10.9 0.7 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 0.3 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 10.9 0.0 0.0 0.2 3.8 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.1 17.9 1.4 17.3 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 38.1 2.8 0.4 0.1 46.5 0.0 663.7 0.0 1.6 15.7 9.2 0.0 0.6 0.0 112.7 0.0 0.8 0.0 5.8 2.9 5.0 9.0 890.7 0.0 205.3 113.2 0.0 0.2 0.0 0.0 0.1 0.3 0.7 47.2 0.0 0.0 128.7 3.4 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "prostate: 163.5" "Cell type enriched" "Detected in some" 36 "Glandular cells: 729.8" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 5.0;NB-4: 10.2" HPA000764 Supported "Secreted in male reproductive system" NA NA "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.0 0.1 0.0 0.1 0.0 1.1 0.2 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.5 0.0 0.1 2.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.2 0.0 2.2 1.9 5.7 2.2 1.6 1.3 0.5 1.7 1.1 0.6 1.6 0.0 0.9 5.0 0.5 0.3 0.2 0.2 0.6 0.8 1.8 0.2 0.0 0.8 2.0 0.2 0.0 0.3 1.7 1.1 0.0 1.3 0.4 0.0 0.3 3.1 0.5 0.3 0.3 0.4 0.5 0.0 1.1 1.5 2.0 0.3 1.8 1.2 10.2 1.1 1.7 0.0 0.9 0.0 2.9 0.0 1.7 0.9 1.6 0.3 1.4 1.3 0.2 1.3 0.4 0.8 1.3 1.9 4.9 1.7 1.8 3.2 0.8 1.9 1.7 1.4 0.9 2.2 1.6 1.2 1.0 1.0 1.0 0.8 1.0 0.5 2.2 0.8 1.3 5.7 1.6 0.8 1.9 0.4 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 13.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 729.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 5.0 0.6 0.0 0.0 0.0 9.2 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 115 "prostate: 447.4" "Cell type enriched" "Detected in some" 62 "Glandular cells: 3142.6" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Region enriched" "Detected in single" 8 "cerebral cortex: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 138 "BEWO: 22.4;NB-4: 18.9;RPMI-8226: 12.5;SH-SY5Y: 7.4;U-2197: 7.6" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" NA NA "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 0.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 447.4 0.0 0.1 3.8 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3142.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 5.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976482-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 29.1;skin 1: 77.5;tongue: 90.2" "Cell type enhanced" "Detected in some" 20 "Alveolar cells type 1: 6.0;Basal keratinocytes: 4.4;Suprabasal keratinocytes: 9.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "CAPAN-2: 6.7;HaCaT: 26.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 960000 "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 2.1 0.3 5.4 0.3 4.3 0.4 5.6 0.5 11.3 5.4 0.3 0.0 0.0 0.5 0.7 0.3 29.1 7.8 3.3 0.2 4.8 0.5 2.6 0.2 1.6 0.3 0.3 3.5 1.0 0.2 0.2 0.1 0.5 4.2 0.3 0.2 0.0 7.4 0.3 0.6 77.5 0.3 0.4 0.3 0.5 0.4 0.3 0.0 0.0 0.4 90.2 15.3 0.2 9.0 1.1 0.4 1.3 0.8 2.1 1.0 0.6 2.7 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 6.7 0.0 1.0 0.0 0.1 26.6 0.0 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.1 1.3 0.8 0.4 0.4 0.4 0.7 0.6 0.6 0.4 0.4 1.1 1.0 0.9 0.9 2.1 0.4 0.4 0.7 0.6 5.4 4.3 0.5 11.3 4.8 0.5 0.3 3.5 4.2 0.0 6.0 0.6 0.0 0.1 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.4 0.0 0.0 0.0 1.8 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.6;skin 1: 40.4;tongue: 46.9" "Group enriched" "Detected in some" 13 "Basal keratinocytes: 58.6;Suprabasal keratinocytes: 157.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 32.2;CAPAN-2: 42.3;HaCaT: 31.2" "Region enriched" "Detected in many" 5 "hippocampal formation: 39.6" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 950000 Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 1.6 0.0 0.1 0.4 0.1 0.0 4.5 1.0 0.3 8.1 0.7 0.1 0.1 0.0 1.1 0.7 43.6 6.7 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 1.1 0.1 0.0 0.1 0.4 0.6 0.3 0.0 0.3 6.0 0.1 0.3 40.4 0.1 0.1 0.6 0.3 0.0 0.7 0.1 0.5 0.3 46.9 11.1 0.3 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.2 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.6 42.3 0.0 0.8 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.3 0.1 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 58.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 1.7 0.0 8.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.4 157.5 0.0 0.0 0.0 0.1 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 102.9" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 203.0" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 7 "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "NTERA-2: 7.3;SCLC-21H: 5.0;SK-MEL-30: 2.2;U-937: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 28900000000 4900000000 "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.3 0.3 0.8 0.3 1.2 0.0 0.3 0.7 0.5 0.3 0.4 0.3 0.3 0.7 0.4 0.4 0.3 0.2 0.7 0.5 0.6 0.5 1.3 102.9 0.3 0.3 0.5 0.5 0.3 1.3 0.5 1.0 0.4 0.4 0.3 0.3 0.5 0.3 0.3 0.5 0.1 0.6 0.3 0.3 0.5 0.0 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 7.3 0.1 0.0 0.1 0.0 0.2 1.3 0.0 5.0 0.4 0.2 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.2 0.7 0.5 0.6 0.5 0.5 0.5 0.4 0.3 0.0 0.0 0.0 0.0 0.0 4.2 3.9 17.8 1.4 0.0 1.8 15.7 0.0 0.0 1.1 2.2 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 203.0 0.2 0.0 2.9 5.5 3.2 0.8 0.6 0.0 0.0 0.0 0.3 14.6 0.7 0.3 0.0 0.9 3.6 0.0 0.2 1.4 0.9 0.0 0.0 0.0 0.4 0.0 KYNU ENSG00000115919 Kynureninase Q16719 2 142877498-143055832 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.9;liver: 41.1;placenta: 34.3" "Cell type enhanced" "Detected in many" 18 "Macrophages: 94.5;monocytes: 360.7;Syncytiotrophoblasts: 87.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 18 "classical monocyte: 28.7;intermediate monocyte: 35.9;memory B-cell: 19.7;myeloid DC: 28.4;naive B-cell: 12.7;non-classical monocyte: 29.2;plasmacytoid DC: 19.9" "Group enriched" "Detected in many" 21 "B-cells: 19.7;dendritic cells: 28.4;monocytes: 35.9" "Cell line enhanced" "Detected in some" "A549: 37.9;GAMG: 62.8;HeLa: 42.3;Hep G2: 25.7;hTEC/SVTERT24-B: 22.2;U-87 MG: 66.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 360000 Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" 9.0 3.7 2.2 11.0 3.7 3.9 15.4 0.6 1.7 3.0 1.2 1.3 0.8 0.2 1.1 2.6 5.6 1.5 4.4 3.8 1.4 1.1 8.4 41.1 12.7 13.7 2.9 0.4 1.7 1.0 0.2 1.6 34.3 2.7 1.9 1.2 1.5 3.0 0.8 0.7 1.5 2.7 2.0 6.3 16.0 2.4 7.0 2.6 2.7 2.2 1.7 13.0 12.4 2.6 19.7 28.4 1.3 35.9 0.4 0.1 11.1 0.0 37.9 0.1 0.1 0.0 0.1 0.1 0.0 1.0 0.0 0.0 0.6 0.5 2.2 0.1 0.0 62.8 0.1 0.0 0.0 0.0 0.1 0.0 0.8 42.3 25.7 0.5 0.1 0.2 3.6 3.1 22.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 19.3 0.0 2.3 0.1 0.0 0.1 0.0 0.2 0.1 0.6 19.6 0.1 0.0 21.0 3.1 0.2 0.2 10.5 5.4 0.3 1.2 0.1 18.5 0.0 0.1 0.0 0.0 66.4 4.4 0.1 0.1 28.7 0.5 0.1 35.9 0.1 19.7 0.1 0.1 28.4 12.7 0.1 0.0 1.3 0.4 29.2 19.9 0.1 11.1 2.2 3.7 0.6 1.7 1.4 1.1 2.9 0.4 2.7 2.6 3.0 2.4 22.6 0.5 3.5 0.1 1.2 5.1 2.7 10.3 3.5 3.9 2.8 5.0 12.1 34.6 2.9 0.0 0.0 7.8 1.5 3.3 0.8 0.0 44.8 38.5 9.5 0.0 3.1 59.7 39.6 1.7 94.5 1.7 360.7 0.0 0.2 37.4 0.0 0.4 23.0 0.5 6.5 1.3 40.0 8.0 2.8 87.5 0.0 0.0 4.2 LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577192-17607972 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hofbauer cells: 227.4;monocytes: 251.5;Proximal tubular cells: 217.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Supported Nucleoplasm,Midbody,Cytosol Yes No 4100000 Cytosol "Nucleoplasm, Midbody" "HPA029606: AB_10599288, HPA029607: AB_10611381" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (4.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.28e-2)" "unprognostic (3.06e-1)" "unprognostic (8.79e-2)" 42.5 29.7 23.2 43.9 38.5 18.1 30.7 8.5 23.5 13.3 21.0 23.5 12.3 27.5 17.2 20.8 19.3 18.7 24.3 25.4 24.4 17.0 71.7 70.3 39.4 54.2 33.7 16.1 13.5 14.7 23.5 13.2 25.0 34.9 15.3 22.7 15.0 23.0 12.1 33.3 20.9 30.6 26.9 35.0 54.9 20.8 19.3 30.7 19.9 29.4 21.7 32.1 24.4 23.7 7.5 45.7 9.5 46.1 11.8 12.9 25.3 10.9 9.6 9.2 8.7 18.3 22.3 0.1 17.3 19.5 62.9 76.5 17.5 20.9 43.2 11.5 13.3 37.5 6.8 34.5 12.2 24.0 16.4 9.9 23.9 10.6 22.8 21.3 21.5 15.4 22.7 7.8 20.6 10.9 7.2 21.8 11.4 23.1 30.9 14.8 11.8 19.1 29.5 19.2 20.6 18.4 29.7 8.8 21.8 16.4 12.9 13.6 11.2 15.8 9.8 33.8 13.3 8.3 8.3 14.1 16.0 10.8 16.8 30.0 28.4 43.4 37.3 21.6 35.9 15.4 8.4 43.4 9.5 8.0 46.1 7.4 7.5 7.5 8.5 45.7 5.2 6.5 6.8 6.2 11.8 31.9 25.9 12.9 25.3 23.2 38.5 8.5 23.5 24.4 17.0 33.7 16.1 34.9 30.7 26.8 44.7 44.2 21.0 19.6 8.0 43.2 10.2 46.8 26.1 26.2 2.0 31.2 99.5 46.8 71.4 104.1 38.5 0.0 96.6 44.5 25.9 23.1 63.4 92.3 227.4 6.4 15.6 68.2 96.6 22.8 21.3 135.7 40.5 251.5 30.0 93.7 42.5 30.2 32.9 217.2 12.6 32.3 24.7 46.4 13.2 19.9 46.6 30.5 39.9 21.7 LCT ENSG00000115850 Lactase P09848 2 135787840-135837180 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "intestine: 255.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Group enriched" "Detected in some" 4 "JURKAT: 3.6;MOLT-4: 6.9;RPMI-8226: 13.7" "Region enriched" "Detected in single" 16 "hippocampal formation: 17.3" NA NA "unprognostic (2.21e-2)" "unprognostic (1.65e-4)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (8.03e-4)" "unprognostic (3.55e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (1.64e-4)" "unprognostic (4.90e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (1.02e-1)" 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 209.8 0.0 0.0 67.7 0.1 0.0 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 255.5 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.7 0.0 0.0 6.9 1.1 0.0 0.0 0.0 1.6 0.0 13.7 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.1 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748702 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 15 "Hofbauer cells: 1236.6;Ito cells: 365.8;Syncytiotrophoblasts: 348.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 11 "plasmacytoid DC: 54.2" "Lineage enriched" "Detected in many" 11 "dendritic cells: 54.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 129.9;U-266/70: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 1200000 Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 42.9 16.3 8.6 17.4 10.7 3.5 19.9 5.8 17.9 13.3 22.3 11.7 13.9 24.2 12.1 48.1 17.4 14.1 32.7 38.8 10.3 10.1 87.6 44.6 31.5 42.4 8.3 10.1 20.5 14.6 54.4 9.7 113.6 9.9 22.0 24.5 23.2 22.6 8.4 17.3 11.9 37.1 23.3 11.5 58.3 23.7 14.0 7.9 17.2 36.8 19.2 17.3 31.4 18.2 4.7 54.2 0.7 0.8 1.0 4.3 1.7 4.9 7.1 4.8 8.7 14.9 12.0 16.7 10.6 10.2 11.1 13.1 5.5 8.9 2.7 15.8 17.4 6.9 12.3 0.0 9.2 5.3 0.2 5.5 0.1 3.9 6.3 4.4 0.1 0.4 8.5 4.5 10.7 6.2 3.3 13.1 5.1 1.0 23.0 0.8 6.6 1.3 0.2 2.3 31.1 4.9 1.2 4.2 129.9 12.0 19.3 5.2 3.5 14.8 9.1 7.7 11.0 6.7 0.0 7.1 5.5 7.0 9.9 3.2 71.5 8.4 3.7 3.1 0.1 10.5 0.7 0.4 0.1 0.2 0.8 0.4 4.7 1.4 0.4 5.0 3.4 4.3 2.5 0.5 1.0 0.2 54.2 2.6 1.7 8.6 10.7 5.8 17.9 10.3 10.1 8.3 10.1 9.9 7.9 53.6 113.7 33.9 33.3 20.5 9.9 25.0 45.9 18.7 34.2 29.6 88.4 130.6 8.3 49.8 0.8 31.3 68.2 0.0 45.2 121.5 45.8 47.6 8.1 36.1 1236.6 12.7 35.1 365.8 242.3 2.3 28.1 82.0 45.5 62.3 31.1 25.8 41.2 52.6 54.5 101.8 15.3 19.4 64.6 22.3 17.7 15.3 348.2 8.5 40.4 39.9 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461834-124617888 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 106.0" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 103.7;Late spermatids: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 880000 "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 9.6 14.2 37.3 6.0 34.0 6.9 7.9 11.9 34.2 12.3 13.6 29.7 8.2 17.9 7.5 11.0 12.7 8.1 8.3 9.8 43.0 31.5 18.6 33.8 6.6 8.2 62.7 19.3 5.5 12.2 6.6 5.6 7.2 20.5 6.9 6.7 6.7 13.3 10.6 6.5 8.9 15.7 8.1 106.0 8.2 12.4 14.2 19.5 7.1 20.5 3.6 11.2 8.7 5.7 24.7 20.0 13.3 16.1 3.9 17.2 12.9 14.8 7.4 3.0 7.6 11.7 9.6 8.0 5.5 11.2 3.5 6.4 1.3 13.8 14.7 12.8 8.2 3.8 16.2 0.9 2.9 3.6 3.3 10.6 10.8 2.4 6.8 12.0 2.1 17.5 7.1 12.6 3.4 8.3 10.2 5.5 13.3 5.3 5.9 4.3 14.7 7.1 6.9 5.3 6.3 4.2 7.6 3.3 18.8 7.5 1.9 1.7 9.1 3.8 14.1 5.0 4.3 10.7 0.3 2.6 5.4 8.0 4.5 1.4 4.9 1.5 4.7 4.9 4.2 1.2 4.6 16.1 13.3 9.5 13.5 12.4 23.7 11.1 10.1 20.0 24.7 13.7 9.6 2.7 3.9 14.9 7.5 17.2 12.9 37.3 34.0 11.9 25.0 43.0 31.5 62.7 19.3 20.5 19.5 3.0 15.0 15.6 9.1 6.5 6.2 12.0 15.3 18.7 12.5 7.0 0.0 44.1 28.2 4.0 103.7 1.6 23.3 0.0 2.1 20.7 9.3 7.6 10.4 53.3 22.8 11.1 9.1 7.4 13.2 124.0 5.5 9.2 16.9 14.4 17.3 6.9 3.5 25.9 9.9 58.6 6.4 12.9 5.1 28.8 10.2 4.6 20.3 7.2 19.6 11.1 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 139.0" "Group enriched" "Detected in many" 7 "Hofbauer cells: 503.3;Kupffer cells: 514.1;Macrophages: 167.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 31.8;intermediate monocyte: 68.4;myeloid DC: 23.3;non-classical monocyte: 35.6" "Group enriched" "Detected in all" 5 "dendritic cells: 23.3;monocytes: 68.4" "Cell line enhanced" "Detected in many" "AN3-CA: 61.6;ASC TERT1: 77.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 150000 "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 139.0 16.3 15.8 14.4 22.7 7.8 19.9 8.8 21.4 13.4 28.1 61.3 3.4 37.4 10.2 5.2 9.5 9.0 19.4 8.7 22.5 13.8 10.8 49.3 38.5 45.7 41.6 13.4 10.4 9.5 17.5 6.3 17.8 28.4 7.4 16.7 5.7 11.0 8.8 4.1 6.8 65.8 11.3 55.1 87.3 7.9 3.1 37.2 7.0 8.3 4.7 10.0 15.1 8.6 7.0 23.3 3.2 68.4 5.5 8.3 25.5 55.0 8.5 5.6 61.6 58.1 77.3 1.6 29.2 34.2 12.2 21.9 3.2 29.7 10.2 5.7 45.7 13.1 55.2 2.4 15.8 9.1 14.3 5.7 4.2 3.6 13.1 15.3 8.1 8.4 34.3 11.4 13.0 7.0 14.8 2.4 7.7 0.0 19.0 9.5 4.6 7.0 5.5 3.6 9.8 9.6 4.6 6.6 9.4 11.3 8.7 1.9 3.9 7.1 9.2 21.5 3.9 10.5 10.5 4.4 10.4 2.7 22.2 7.1 9.9 10.5 4.2 12.4 18.0 13.0 0.8 31.8 3.2 8.2 68.4 8.2 6.5 7.3 7.8 23.3 7.0 7.7 8.3 1.4 5.5 35.6 4.7 7.1 25.5 15.8 22.7 8.8 21.4 22.5 13.8 41.6 13.4 28.4 37.2 38.7 42.2 50.6 22.0 15.8 5.2 8.5 45.9 14.7 13.6 31.4 0.0 28.4 18.3 29.7 4.4 53.1 3.9 23.3 31.7 28.0 34.8 15.2 27.7 46.5 503.3 15.9 20.9 52.8 514.1 1.8 10.6 167.0 45.5 27.9 9.4 29.4 17.5 5.9 20.5 14.6 1.3 6.5 21.8 4.8 10.9 10.9 16.7 33.0 8.7 20.1 LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569843 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 91.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 125.3" "Group enriched" "Detected in some" 14 "liver cancer: 20.4;renal cancer: 10.4" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "granulocytes: 3.7;NK-cells: 3.0;T-cells: 4.5" "Cell line enhanced" "Detected in some" "CACO-2: 7.0;EFO-21: 5.3;Hep G2: 20.0;HMC-1: 5.9;MOLT-4: 4.5;U-2197: 15.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 3200000 "unprognostic (1.76e-2)" "unprognostic (9.15e-3)" "unprognostic (7.89e-2)" "unprognostic (7.15e-4)" "unprognostic (1.40e-1)" "unprognostic (1.33e-2)" "unprognostic (9.93e-3)" "unprognostic (6.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.10e-2)" "unprognostic (3.06e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.87e-2)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" 0.2 0.1 0.4 1.1 0.7 0.0 0.7 0.1 0.4 0.3 0.2 0.6 0.0 0.7 0.1 0.4 0.2 0.4 0.3 0.3 0.4 0.2 3.0 91.7 0.3 0.2 1.2 0.2 0.3 1.0 0.0 1.0 0.1 1.5 0.3 0.3 0.5 0.1 1.5 0.1 0.3 0.3 0.1 1.2 0.4 0.2 0.1 0.5 2.7 0.5 0.0 0.1 1.1 0.2 0.1 0.2 3.7 0.4 3.0 4.5 2.5 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.7 0.0 0.0 7.0 0.0 0.0 5.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 2.5 0.0 20.0 0.4 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.1 4.5 0.6 0.0 0.0 0.0 0.9 0.3 0.0 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.8 0.0 0.0 0.0 0.1 0.1 0.4 0.0 3.7 0.3 0.0 3.0 0.2 4.5 0.0 0.8 2.2 0.2 0.1 1.0 3.2 0.4 3.0 0.4 0.1 2.1 2.5 0.4 0.7 0.1 0.4 0.4 0.2 1.2 0.2 1.5 0.5 0.0 0.0 5.1 0.0 0.2 0.0 0.8 12.7 0.0 1.2 3.5 0.0 0.0 5.0 3.7 0.0 0.0 0.0 0.0 3.3 0.0 1.2 0.2 0.0 125.3 0.1 0.0 0.0 5.5 4.0 0.0 0.3 0.0 1.7 1.0 0.0 0.0 0.3 0.0 0.0 9.6 0.0 0.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401507-42427426 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 207.4;breast: 65.1" "Group enriched" "Detected in many" 6 "Early spermatids: 123.5;Late spermatids: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 207.4 6.0 3.2 2.9 9.4 2.1 65.1 2.0 6.8 1.2 6.7 19.6 0.8 2.4 1.7 1.3 2.2 1.6 3.6 4.8 6.2 4.2 1.5 1.1 1.4 2.7 18.0 2.3 1.5 2.2 2.2 0.8 1.7 9.9 1.7 1.3 3.7 5.4 1.7 3.7 2.9 3.4 1.7 19.2 3.1 1.6 9.0 10.8 1.7 1.5 1.8 1.9 2.0 3.7 6.1 4.8 10.8 12.1 4.1 5.2 4.0 4.9 3.8 2.5 0.9 57.3 0.5 0.0 2.3 1.3 3.7 3.5 0.9 1.9 8.2 2.6 0.7 1.8 2.2 1.5 4.6 0.4 1.5 2.4 2.3 1.8 0.1 1.1 0.0 5.6 0.5 4.4 0.6 0.8 0.5 1.0 3.4 1.0 5.2 0.5 0.0 5.7 0.2 0.3 3.8 1.1 4.7 0.4 2.7 1.0 5.2 3.5 3.6 2.0 2.3 2.1 0.1 0.6 3.0 1.9 1.0 3.2 0.4 2.1 3.9 3.2 6.1 2.6 0.2 3.5 10.8 12.1 4.7 3.6 6.0 3.3 4.8 4.6 5.2 4.8 6.1 4.1 3.7 2.0 4.1 3.3 3.9 3.9 4.0 3.2 9.4 2.0 6.8 6.2 4.2 18.0 2.3 9.9 10.8 0.0 3.5 1.3 10.1 3.7 8.1 2.2 0.0 0.0 0.0 1.8 9.8 0.0 1.7 6.4 123.5 4.5 3.2 23.3 2.4 0.1 1.7 5.2 0.0 0.0 0.6 7.9 0.0 17.8 1.8 188.1 2.8 1.2 5.0 0.0 1.1 3.3 1.4 0.0 1.4 1.1 12.3 0.0 1.0 26.8 12.4 2.0 0.0 6.9 2.7 9.0 LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "stomach 1: 762.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Cell type enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "HMC-1: 6.4;MOLT-4: 5.0;NTERA-2: 5.3;REH: 3.1;THP-1: 10.0;U-2 OS: 3.6;U-266/70: 4.9" "Region enriched" "Detected in single" 51 "olfactory region: 9.9" HPA045930 Enhanced "Secreted to digestive system" NA NA "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.1 1.9 0.1 0.2 28.2 0.1 8.2 0.1 0.1 31.6 0.1 0.6 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 9.9 0.1 0.1 0.0 0.1 0.1 0.1 0.1 762.9 0.1 0.1 0.2 0.1 1.1 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.1 5.3 0.0 0.0 3.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 3.6 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 1.9 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599182 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.0;placenta: 44.7;thyroid gland: 84.3" "Cell type enhanced" "Detected in many" 9 "Cone photoreceptor cells: 56.9;Extravillous trophoblasts: 60.0;Hepatocytes: 66.8" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 31.4;HaCaT: 48.1;RPTEC TERT1: 32.0;TIME: 62.4" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 2.1;cerebral cortex: 2.9;hippocampal formation: 1.8;olfactory region: 1.9" "Low region specificity" "Detected in many" HPA016966 Uncertain "Secreted to blood" NA NA 657000000 170000 "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 1.5 0.4 0.8 4.7 0.7 0.1 0.8 2.0 0.7 0.4 5.6 3.9 15.0 1.9 0.4 3.1 1.0 0.5 4.3 1.2 1.1 0.9 5.2 37.0 4.4 0.7 1.1 0.1 0.5 1.0 0.0 0.6 44.7 1.4 1.0 2.2 8.3 0.6 24.6 2.6 1.1 7.6 2.2 1.4 0.4 1.4 5.8 0.4 0.3 84.3 2.1 0.5 2.0 0.6 1.2 0.6 2.1 0.6 1.7 0.8 0.1 0.5 0.0 13.8 31.4 0.1 0.0 0.2 0.1 1.4 0.0 0.0 13.6 4.9 0.0 7.6 0.0 9.6 48.1 2.0 9.8 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.2 1.4 11.1 4.9 9.6 0.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.1 0.0 0.0 0.7 32.0 3.7 0.2 0.0 0.2 0.3 0.0 1.8 0.0 0.0 62.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.4 0.7 0.4 0.4 0.8 0.5 0.5 0.2 1.2 0.8 0.7 2.1 1.7 0.4 0.6 0.4 0.1 0.8 0.7 2.0 0.5 1.1 0.9 1.1 0.1 1.4 0.4 0.0 1.4 0.0 4.8 1.5 0.8 1.7 25.5 0.0 3.4 14.0 56.9 4.7 0.0 3.2 8.0 1.4 9.5 0.0 1.2 60.0 1.0 8.4 0.0 66.8 1.6 0.0 13.3 4.9 1.9 6.0 0.3 0.0 1.7 1.0 3.4 1.0 7.7 2.9 0.0 1.0 2.4 0.0 0.7 1.0 0.8 2.3 16.2 0.7 6.2 9.9 LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037515 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 104.4" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" NA NA 390000 "HPA043642: AB_10964137" "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-2)" "unprognostic (6.38e-2)" "unprognostic (6.59e-3)" "unprognostic (6.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.11e-1)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.28e-1)" "unprognostic (4.13e-3)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" 9.8 4.7 5.6 12.0 7.3 13.2 7.7 23.3 12.9 6.3 7.6 6.9 7.8 4.2 8.2 4.4 10.2 6.6 4.3 10.1 5.2 5.6 7.6 4.3 6.9 15.9 7.7 8.8 8.2 5.9 13.8 9.7 104.4 9.1 7.9 6.8 3.9 7.8 7.7 13.2 14.0 9.0 6.6 7.5 10.0 8.5 3.3 7.7 23.6 7.2 2.9 15.8 8.9 7.7 4.1 3.5 5.0 12.8 11.2 7.9 4.3 5.3 6.2 2.8 2.9 17.1 8.2 3.3 5.5 7.3 6.5 9.9 5.2 8.7 26.5 10.4 7.4 18.3 7.1 3.6 10.4 6.8 9.4 2.0 6.6 4.5 3.6 4.4 7.6 9.1 6.3 6.4 9.4 6.9 7.0 6.8 5.9 2.8 17.6 7.4 4.7 9.0 5.3 0.6 1.7 3.3 6.5 10.6 4.0 23.2 11.1 5.5 1.4 6.7 5.9 3.3 2.8 18.1 10.0 13.5 9.5 5.3 7.5 8.3 3.8 8.8 24.2 8.4 7.2 4.3 5.0 3.3 4.4 7.9 5.5 6.8 3.1 5.9 6.1 3.5 4.1 5.9 6.4 4.1 11.2 12.8 3.3 5.1 4.3 5.6 7.3 23.3 12.9 5.2 5.6 7.7 8.8 9.1 7.7 32.8 42.4 53.7 16.7 52.8 57.3 58.2 17.8 22.7 20.5 34.9 117.8 9.5 5.0 14.0 2.4 31.5 15.8 0.0 12.3 21.8 30.1 24.6 24.4 14.1 14.7 22.3 24.6 33.7 46.5 3.8 30.5 38.3 20.3 12.6 27.8 43.8 15.9 14.0 43.9 9.1 35.8 25.8 24.7 21.4 23.1 41.3 22.9 70.5 21.5 19.9 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 78.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria No No Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 15.8 78.3 16.4 12.8 19.8 12.5 13.9 16.1 22.8 11.3 13.6 15.8 13.3 13.7 10.5 13.8 12.7 12.7 15.7 27.3 15.4 15.3 19.9 49.6 10.3 14.5 17.7 14.9 15.5 17.7 17.6 16.8 16.6 16.2 11.7 8.5 12.7 18.5 14.7 38.0 14.7 13.9 11.5 12.7 15.5 13.5 9.8 13.3 13.8 21.2 15.3 11.8 14.7 12.5 6.7 6.5 6.0 6.2 4.0 7.2 3.0 23.0 23.9 7.9 25.3 9.4 6.7 24.7 14.7 11.7 15.9 19.5 20.4 8.3 28.9 20.6 15.4 15.3 9.8 20.4 17.8 7.7 17.1 16.8 16.0 20.9 26.7 43.7 36.4 16.8 12.6 25.6 15.1 29.9 7.7 12.7 40.6 42.3 57.8 7.3 15.3 18.0 21.7 28.3 9.4 31.6 19.0 11.4 31.2 8.8 13.7 21.1 21.1 12.9 18.9 51.6 5.8 11.1 45.7 8.9 8.1 8.9 22.5 21.4 60.9 37.5 25.7 36.5 39.9 14.6 6.0 4.1 0.8 6.4 6.2 4.1 6.0 5.6 6.1 4.3 6.7 7.2 4.8 0.5 4.0 2.4 6.5 4.0 3.0 16.4 19.8 16.1 22.8 15.4 15.3 17.7 14.9 16.2 13.3 6.0 13.3 13.7 8.7 7.3 24.7 17.9 15.3 9.4 10.3 26.2 5.9 24.8 39.7 28.3 5.3 9.8 24.8 0.0 23.9 27.0 10.5 12.9 5.7 44.0 28.2 20.6 10.9 14.1 11.3 4.0 11.8 15.2 13.5 24.4 21.6 20.9 25.6 14.4 16.3 36.0 22.0 19.4 10.3 9.1 13.4 9.4 29.3 9.2 22.2 9.4 LONP2 "LONP, LONPL, MGC4840" ENSG00000102910 "Lon peptidase 2, peroxisomal" Q86WA8 16 48244296-48363122 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008862 Uncertain NA NA "HPA008862: AB_2137156" "unprognostic (8.08e-3)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.75e-2)" "unprognostic (2.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.60e-2)" "unprognostic (7.59e-3)" "unprognostic (2.13e-1)" "unprognostic (2.36e-1)" "unprognostic (3.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.71e-7)" "unprognostic (6.53e-2)" "unprognostic (1.49e-1)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" 15.8 17.0 16.0 13.9 22.2 9.4 36.1 18.9 20.7 16.1 17.4 16.3 15.3 15.2 15.8 20.6 14.5 17.6 19.0 16.7 15.0 15.0 15.9 69.2 11.3 12.8 15.2 15.8 22.1 20.7 40.0 23.3 11.1 17.2 23.1 14.8 30.9 15.0 18.1 18.0 13.5 14.8 16.3 14.1 12.5 14.9 7.0 13.7 14.9 24.9 11.6 13.2 16.7 13.7 13.3 13.1 8.7 13.7 9.0 15.9 11.0 13.9 19.4 9.8 15.0 25.9 21.4 18.5 17.9 13.7 16.9 7.7 10.1 7.1 6.4 17.7 17.9 8.0 17.4 19.8 19.8 23.6 10.3 12.5 9.3 12.4 21.9 15.9 15.6 12.5 19.8 22.1 15.7 14.9 20.4 12.5 11.8 15.6 6.9 17.4 12.5 15.0 7.7 8.2 12.8 19.4 19.6 19.9 20.1 19.1 9.4 17.1 10.2 20.3 22.8 18.0 14.4 9.5 11.9 16.6 17.4 10.3 15.1 13.7 13.9 12.6 10.5 20.3 10.5 12.6 6.8 13.7 8.7 13.3 13.6 14.0 12.8 15.9 13.5 13.1 13.3 15.0 13.8 5.3 9.0 13.6 9.6 11.8 11.0 16.0 22.2 18.9 20.7 15.0 15.0 15.2 15.8 17.2 13.7 53.6 63.0 42.5 37.4 31.0 101.1 54.8 68.8 61.6 62.6 26.2 80.5 31.9 11.6 27.4 20.1 29.1 31.6 0.0 26.8 24.3 34.0 48.5 29.0 162.5 26.1 81.0 47.7 43.0 49.7 8.7 54.7 33.7 37.1 36.1 34.2 84.0 28.2 34.5 51.2 24.5 148.4 38.8 29.2 18.2 15.6 32.1 53.5 32.8 38.2 39.1 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1310.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 18.1 10.1 13.0 10.7 18.3 6.0 22.1 20.0 16.4 10.5 8.6 10.9 7.3 8.9 11.0 15.0 20.0 7.0 10.4 12.8 11.6 11.9 7.6 13.2 8.0 15.4 13.2 11.2 19.3 7.5 17.2 32.0 9.0 17.9 9.6 7.1 9.0 14.4 11.6 88.4 6.5 9.2 11.0 10.3 8.4 7.6 39.0 13.2 8.3 8.1 14.0 19.2 10.4 21.7 6.5 9.6 11.6 2.8 8.0 11.1 3.2 5.5 6.6 5.5 12.3 25.5 28.4 2.8 7.8 13.4 5.0 8.7 2.4 5.5 2.7 1.0 6.6 14.8 6.0 6.2 17.0 4.6 11.4 3.4 6.8 3.7 3.5 9.0 4.7 32.1 25.6 7.7 20.8 7.9 14.7 9.7 6.7 9.4 24.7 3.7 2.1 4.4 4.1 5.7 1.8 6.7 6.1 10.1 17.3 12.7 3.6 15.3 12.1 2.8 6.8 17.5 5.5 1.7 2.6 6.8 8.0 7.2 5.1 6.7 38.8 30.0 5.2 11.3 8.4 5.9 9.5 2.8 11.6 10.3 2.1 11.1 6.5 9.6 9.7 2.5 5.0 8.4 7.1 1.1 8.0 2.1 9.6 10.5 3.2 13.0 18.3 20.0 14.4 11.6 11.9 13.2 11.2 17.9 13.2 20.8 49.1 22.9 38.9 16.9 40.6 49.5 25.5 61.6 63.7 10.4 80.5 7.3 6.6 18.7 314.7 24.6 9.7 0.0 24.2 5.3 24.6 29.2 33.6 21.9 8.1 46.1 34.7 15.4 15.7 1310.7 110.1 27.2 16.9 7.2 23.9 16.4 25.5 11.6 169.0 3.4 47.2 32.3 20.6 18.4 17.8 10.5 10.3 57.5 13.6 26.8 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013315 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease mutation, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Cell type enhanced" "Detected in all" 5 "Cholangiocytes: 140.1;Hepatocytes: 111.5;Horizontal cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 6 "granulocytes: 20.8;NK-cells: 10.1;T-cells: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 6.8 5.6 13.0 10.5 18.4 9.2 7.7 11.9 16.5 6.6 25.2 10.4 2.4 31.6 6.7 3.9 5.9 6.3 14.3 5.1 11.0 14.5 20.7 83.9 11.8 11.8 11.2 9.8 8.8 9.0 9.7 8.2 16.3 15.3 5.8 7.4 6.8 4.4 5.3 2.2 2.7 43.3 6.1 9.6 10.7 15.6 13.5 9.6 6.3 7.5 1.5 10.0 6.8 6.7 1.2 1.1 20.8 2.0 10.1 9.5 2.1 4.9 6.7 10.6 3.7 18.4 17.1 6.3 12.0 14.6 11.9 11.6 8.7 4.2 3.6 7.3 18.3 18.6 0.2 8.7 3.7 9.4 7.0 1.8 9.2 5.2 9.9 17.2 7.3 10.2 17.2 2.5 11.8 10.3 17.3 14.8 8.8 8.3 1.9 16.7 3.7 9.1 6.3 3.4 7.4 9.6 16.1 9.2 13.4 9.5 11.1 9.0 6.2 11.2 5.3 3.8 6.4 0.0 10.1 20.8 15.4 18.7 19.7 8.8 3.5 5.3 7.8 13.6 7.5 5.4 6.5 2.0 6.1 9.3 1.3 9.5 0.9 7.1 5.3 0.8 1.2 7.3 4.7 20.8 10.1 0.6 1.1 6.3 2.1 13.0 18.4 11.9 16.5 11.0 14.5 11.2 9.8 15.3 9.6 62.5 38.2 16.9 8.2 4.9 31.9 10.4 140.1 21.4 35.2 36.6 13.7 17.4 14.9 9.7 2.1 17.5 52.0 46.7 16.6 9.6 15.9 14.5 11.6 111.5 19.6 109.7 14.3 20.3 21.0 6.9 21.0 19.9 8.5 24.4 30.3 16.0 18.6 10.5 29.4 40.8 14.8 6.5 9.9 28.8 59.6 1.8 41.4 39.9 11.9 3.4 LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340920-41360582 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 49.1" "Cell type enhanced" "Detected in many" 9 "Enterocytes: 49.9;Late spermatids: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "NK-cell: 6.3" "Group enriched" "Detected in many" 4 "granulocytes: 1.8;NK-cells: 6.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol NA NA Cytosol "HPA051466: , HPA052667: AB_2681908, HPA070640: AB_2686288" "unprognostic (2.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (6.91e-3)" "unprognostic (4.26e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.74e-4)" "unprognostic (4.29e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (5.60e-3)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (3.37e-3)" 11.6 3.7 3.0 8.1 5.2 0.1 23.4 1.5 3.0 10.9 29.2 2.8 13.5 26.8 12.8 21.6 16.3 7.5 11.2 8.8 3.6 0.7 28.2 14.4 4.5 1.6 2.8 3.7 7.9 7.4 8.1 6.7 4.4 4.2 10.1 8.8 8.7 11.0 15.1 1.8 26.1 49.1 5.5 2.4 2.7 7.4 2.5 1.5 1.2 14.2 10.6 9.0 8.0 12.5 0.9 0.7 1.8 0.9 6.3 0.8 0.2 6.9 6.8 0.4 4.1 11.2 17.5 5.3 4.3 6.0 5.3 7.2 12.7 6.2 0.3 5.4 9.4 5.6 17.7 2.1 11.2 3.3 0.1 4.0 0.3 9.6 6.4 1.8 0.0 4.8 12.6 14.3 8.9 3.5 6.2 1.3 0.1 1.8 0.2 6.6 14.9 0.0 0.1 0.6 4.3 7.1 0.0 0.1 0.5 18.4 8.8 0.5 0.1 5.7 7.4 3.6 3.5 8.6 3.5 0.4 0.3 1.7 5.9 0.0 3.4 1.8 0.0 0.1 0.1 0.3 1.8 0.5 0.7 0.5 0.5 0.8 0.6 0.7 0.4 0.3 0.9 0.7 0.6 1.8 6.3 0.9 0.7 0.5 0.2 3.0 5.2 1.5 3.0 3.6 0.7 2.8 3.7 4.2 1.5 6.0 10.5 0.8 8.2 12.8 0.0 0.6 10.2 1.4 4.5 10.4 0.0 2.3 5.0 7.4 10.4 2.1 49.9 0.0 3.3 2.2 7.7 3.5 1.1 33.7 2.7 0.0 14.3 4.3 1.3 82.8 2.8 1.5 10.1 0.0 16.6 7.5 5.5 21.6 2.5 5.9 0.3 32.3 6.4 0.9 2.1 11.0 2.2 1.3 16.2 3.9 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967258 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease mutation, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 178.6;breast: 146.2;heart muscle: 121.4" "Cell type enhanced" "Detected in many" 20 "Cardiomyocytes: 482.3;Hofbauer cells: 114.1;Horizontal cells: 195.5;Sertoli cells: 232.8" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Region enhanced" "Detected in many" "basal ganglia: 16.3" "Cell type enhanced" "Detected in some" "non-classical monocyte: 7.1" "Lineage enriched" "Detected in many" 5 "monocytes: 7.1" "Cell line enriched" "Detected in some" 5 "AF22: 91.4" "Region enhanced" "Detected in many" "basal ganglia: 40.6" "Region enriched" "Detected in many" 4 "basal ganglia: 64.0" HPA048749 Supported Vesicles "Secreted to blood" NA NA 880000 Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 178.6 4.3 2.0 11.4 16.3 0.6 146.2 3.9 8.0 1.0 16.9 0.3 27.3 0.8 1.3 1.1 1.1 0.7 8.2 121.4 2.8 2.3 4.8 0.6 20.7 7.0 4.5 0.7 2.7 1.8 32.6 0.9 7.1 1.7 0.9 1.8 8.4 9.2 85.1 53.8 1.8 3.1 1.3 2.8 0.8 1.8 0.7 3.4 0.0 2.7 9.7 1.0 3.2 6.1 0.0 0.7 1.3 7.1 0.0 0.1 0.4 0.0 0.0 91.4 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 14.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 3.5 0.0 0.4 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.4 0.0 1.6 1.3 0.0 2.8 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.4 2.0 16.3 3.9 2.3 2.8 2.3 4.5 0.7 1.7 3.4 11.9 93.6 0.0 0.1 1.3 1.0 482.3 0.0 5.3 1.2 0.0 2.0 0.3 13.3 0.0 0.6 5.4 0.0 0.0 0.0 0.6 3.1 0.3 5.8 0.0 114.1 195.5 0.0 4.3 13.4 1.0 1.1 23.8 13.5 2.8 0.0 1.7 0.0 0.0 0.0 0.0 2.2 232.8 19.1 0.3 0.2 0.5 0.3 0.0 0.0 0.1 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000828-96043520 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 215.6;Kupffer cells: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol NA NA 85000000 "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favorable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favorable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 27.9 33.2 11.2 21.5 16.7 55.7 19.0 24.1 15.6 27.2 29.1 13.1 16.7 27.6 27.6 14.1 53.4 22.7 14.5 19.2 10.6 12.2 27.2 19.4 68.0 33.4 12.3 11.3 49.9 28.2 21.2 31.8 11.3 13.3 29.6 17.8 20.7 21.1 16.1 20.6 23.6 41.2 21.5 13.3 44.3 22.1 13.7 11.5 29.2 38.8 22.3 43.1 30.1 25.2 20.6 35.3 6.1 84.2 14.2 9.0 54.6 21.0 22.6 31.8 18.9 27.6 30.9 13.9 8.8 26.1 17.4 20.3 16.5 18.2 47.1 11.1 13.1 13.7 27.7 26.0 35.9 23.8 16.1 25.2 17.3 14.5 20.0 16.3 9.1 10.5 29.4 30.3 24.0 29.5 79.5 34.5 27.6 10.5 8.3 25.1 14.4 23.9 28.0 37.0 25.1 30.7 22.4 23.7 27.1 32.0 26.8 16.5 19.5 17.8 20.8 19.1 25.5 25.9 11.2 12.3 7.4 12.5 10.5 9.5 11.2 19.4 21.8 5.2 16.5 5.8 0.4 76.0 2.2 4.5 84.2 8.4 15.1 6.3 5.8 35.3 20.6 9.0 6.7 6.1 14.2 73.2 8.7 6.3 54.6 11.2 16.7 24.1 15.6 10.6 12.2 12.3 11.3 13.3 11.5 35.7 107.1 87.8 57.2 46.0 19.4 23.4 17.8 48.2 91.0 36.6 31.4 27.0 63.0 34.2 44.9 33.1 22.4 0.0 24.3 24.3 27.5 27.6 7.0 18.1 215.6 11.1 20.7 47.3 278.8 8.1 33.9 139.0 20.3 38.7 40.9 32.1 23.4 24.6 38.5 53.1 58.0 6.5 18.5 45.1 12.5 65.5 17.4 34.8 53.6 42.1 LYZ ENSG00000090382 Lysozyme P61626 12 69348341-69354234 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 490.0;salivary gland: 1017.8" "Cell type enhanced" "Detected in many" 16 "Kupffer cells: 3040.5;Macrophages: 4386.3;Pancreatic endocrine cells: 1930.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "classical monocyte: 490.0;myeloid DC: 308.1" "Group enriched" "Detected in all" 18 "dendritic cells: 308.1;monocytes: 490.0" "Cell line enriched" "Detected in some" 13 "OE19: 521.4" "Not detected" "Not detected" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 2600000000 "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 19.1 2.4 1.7 42.1 1.8 187.0 2.9 1.6 1.6 2.9 52.5 2.0 0.1 72.4 2.3 6.9 3.9 3.4 105.0 15.4 1.8 1.8 4.8 4.8 81.0 57.2 2.1 0.0 4.5 5.0 0.0 1.8 8.3 0.9 2.4 5.0 2.7 1017.8 2.8 1.8 2.1 95.0 1.8 2.5 34.2 212.1 1.6 0.5 24.5 2.4 207.7 75.7 6.6 2.4 1.6 308.1 21.9 490.0 2.3 1.1 407.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 39.8 0.0 4.6 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 4.5 0.1 521.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 22.3 0.0 7.5 490.0 5.9 0.7 102.3 1.1 1.6 0.4 0.5 308.1 0.4 0.4 0.4 21.9 2.3 17.6 6.5 0.6 407.9 1.7 1.8 1.6 1.6 1.8 1.8 2.1 0.0 0.9 0.5 80.4 424.7 79.8 2.3 50.8 0.1 0.0 815.3 52.2 87.6 26.2 0.0 4.1 0.0 46.7 1.4 10.8 19.6 0.0 484.8 7.4 19.7 4.1 113.9 7.3 924.7 0.0 12.0 37.4 3040.5 3.7 3.7 4386.3 50.6 757.4 61.5 0.0 1930.3 401.2 2.1 5.0 1.1 38.8 3.9 0.6 2.3 33.4 7.1 13.8 38.3 2.2 LYZL1 "LYC2, MGC33408" ENSG00000120563 "Lysozyme like 1" Q6UWQ5 10 29289061-29318328 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 371 "testis: 39.5" "Group enriched" "Detected in some" 48 "Early spermatids: 474.4;Late spermatids: 148.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.0;SuSa: 2.9" "Secreted in male reproductive system" NA NA "unprognostic (1.88e-1)" "unprognostic (8.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 474.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 6.5 0.0 4.2 1.9 0.0 0.0 0.0 0.0 0.0 LYZL2 ENSG00000151033 "Lysozyme like 2" Q7Z4W2 10 30611779-30629762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "testis: 34.2" "Group enriched" "Detected in some" 53 "Early spermatids: 605.6;Late spermatids: 151.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SK-BR-3: 8.2" "Secreted in male reproductive system" NA NA "unprognostic (2.83e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 605.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.6 1.6 0.0 0.0 0.0 0.0 0.0 LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943699 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "testis: 33.2" "Cell type enriched" "Detected in some" 10 "Early spermatids: 287.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "NB-4: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" NA NA "HPA025734: AB_1853444, HPA053073: AB_2682034" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 287.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.1 2.5 0.0 0.0 0.0 0.0 0.0 MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177209-119349761 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.2" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 149.9;Hepatocytes: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 60.3;Hep G2: 42.3;Karpas-707: 47.2;U-266/70: 63.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 390000000 "Golgi apparatus" "CAB037058: AB_477183, HPA053198: AB_2682078, HPA063561: AB_2685042" "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" 41.8 19.8 5.8 10.5 17.4 8.1 32.2 1.5 7.9 12.3 23.3 3.2 3.6 17.4 11.3 12.0 10.6 9.5 22.0 10.4 5.0 3.3 23.4 74.2 16.4 16.8 2.8 5.7 10.3 22.0 3.4 6.4 26.1 3.7 14.7 9.9 10.5 41.0 5.3 7.1 9.6 36.3 19.7 3.5 20.9 10.0 8.7 3.7 8.8 15.2 10.3 9.1 21.2 36.4 1.4 5.5 6.0 1.1 1.9 4.7 0.6 0.0 0.0 0.7 0.0 60.3 26.7 1.4 1.4 8.8 1.1 2.7 4.1 0.5 9.0 0.0 5.5 14.2 0.1 1.6 0.0 1.4 13.3 4.1 7.5 0.8 42.3 6.0 0.0 3.8 18.2 1.1 9.0 5.5 4.8 0.7 2.6 26.0 47.2 8.5 1.2 0.3 0.0 0.5 4.1 2.1 2.5 0.9 13.6 2.9 7.4 3.0 4.5 0.0 0.1 0.0 1.9 2.2 1.0 5.2 3.7 3.4 6.9 3.3 63.8 9.0 17.8 10.9 0.1 2.2 6.0 0.6 2.0 2.4 1.1 4.7 1.4 1.3 1.3 0.6 0.9 0.8 1.9 3.8 1.9 0.9 5.5 1.4 0.6 5.8 17.4 1.5 7.9 5.0 3.3 2.8 5.7 3.7 3.7 8.9 36.6 18.6 5.7 28.2 18.6 3.9 45.9 8.1 11.4 101.2 0.0 4.7 5.0 5.1 149.9 42.5 42.8 23.3 32.8 8.0 90.1 5.0 3.5 232.5 81.6 0.0 46.1 103.7 76.4 24.4 24.5 57.9 27.0 6.4 55.5 1.3 20.9 14.4 3.9 32.2 4.7 6.5 18.1 2.1 3.9 24.3 5.1 26.1 11.5 7.6 MAN1A2 MAN1B ENSG00000198162 "Mannosidase alpha class 1A member 2" O60476 1 117367449-117528872 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "placenta: 122.4" "Cell type enhanced" "Detected in all" 7 "Extravillous trophoblasts: 201.3;Syncytiotrophoblasts: 318.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034559, HPA057364" Enhanced Enhanced "Golgi apparatus" NA NA 1100000 "Golgi apparatus" "HPA034559: AB_10671229, HPA057364: AB_2683419" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-3)" "unprognostic (2.15e-1)" "unprognostic (3.11e-2)" "unprognostic (9.70e-2)" "unprognostic (1.95e-2)" "unprognostic (8.01e-2)" "unprognostic (8.19e-3)" "prognostic favorable (4.08e-4)" "unprognostic (1.41e-1)" "unprognostic (4.38e-2)" "unprognostic (6.84e-2)" "unprognostic (1.45e-1)" "unprognostic (7.39e-2)" "unprognostic (1.17e-1)" "unprognostic (5.08e-2)" 11.1 9.7 13.9 9.1 15.8 3.8 9.7 11.9 15.2 14.4 10.7 8.5 9.4 8.1 15.8 10.7 11.5 12.2 9.2 11.0 11.2 9.2 11.8 16.4 8.1 9.9 12.0 13.9 11.2 27.4 21.7 9.6 122.4 11.3 11.2 9.5 8.3 11.1 10.5 10.5 7.5 9.0 13.7 10.4 10.4 10.3 10.1 14.4 16.1 19.4 6.9 9.8 13.6 9.8 3.7 4.4 4.0 2.7 6.0 9.8 2.4 14.4 6.3 10.8 9.3 14.2 17.1 34.6 12.0 18.8 5.4 5.1 4.8 8.3 10.8 22.3 15.4 5.1 8.6 5.0 10.2 12.2 13.5 7.6 6.4 8.9 5.3 8.6 10.0 14.8 11.5 11.0 8.3 7.3 10.0 16.1 7.6 10.3 16.7 11.3 28.1 6.1 3.2 5.5 7.3 6.6 5.5 23.5 7.4 7.5 19.7 5.9 8.6 11.9 12.8 9.4 14.7 6.3 6.4 15.3 12.2 10.1 8.6 12.2 11.4 7.7 7.3 16.2 8.0 29.0 1.3 2.7 4.0 5.2 2.1 6.2 3.3 4.3 4.3 2.3 3.7 3.6 5.2 2.1 6.0 1.7 4.4 9.8 2.4 13.9 15.8 11.9 15.2 11.2 9.2 12.0 13.9 11.3 14.4 35.7 30.2 42.7 29.6 27.5 59.3 85.6 35.7 42.8 40.9 41.8 21.6 40.9 14.9 26.4 27.9 33.3 25.6 23.3 52.0 201.3 31.7 37.6 15.1 78.0 25.6 41.3 20.8 34.4 30.7 15.9 49.8 22.8 38.8 12.6 32.4 40.2 36.9 21.0 61.5 21.5 39.0 38.8 29.1 63.9 52.5 30.2 318.2 30.5 26.4 37.2 MAN1B1 "ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086927-137109187 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles NA NA 540000 Vesicles "HPA051516: AB_2681518" "unprognostic (1.21e-2)" "unprognostic (4.66e-1)" "unprognostic (1.25e-3)" "unprognostic (4.67e-3)" "unprognostic (2.27e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-2)" "unprognostic (5.93e-3)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (5.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.44e-3)" 20.4 25.4 19.7 13.5 23.7 9.8 18.6 21.6 36.1 24.3 21.6 24.5 20.6 19.8 22.7 28.1 23.1 28.9 25.9 19.5 20.5 21.5 24.3 32.7 20.4 19.9 18.6 25.2 24.2 32.6 23.6 25.1 30.8 18.0 21.2 12.0 22.0 32.7 23.1 12.2 25.4 17.8 18.5 16.4 22.2 21.8 30.3 18.2 19.9 25.1 12.7 19.3 21.0 16.0 13.0 23.0 16.3 24.4 18.0 21.9 18.5 7.2 17.1 6.0 16.9 22.5 19.4 19.8 12.4 26.2 16.5 14.7 8.4 22.9 6.6 41.5 20.6 23.3 25.1 3.6 12.0 3.0 9.1 6.0 2.9 15.4 9.6 21.3 5.1 11.4 22.9 22.7 9.6 8.1 22.1 10.9 8.9 8.0 10.9 11.7 14.7 5.4 12.1 8.0 21.4 17.3 3.1 10.0 20.9 13.2 3.6 6.9 6.2 18.3 19.4 12.6 3.2 21.6 10.9 15.3 24.5 9.1 18.0 14.4 4.4 3.6 4.4 29.4 6.5 21.0 7.9 20.1 16.3 21.9 21.8 20.5 13.0 17.3 20.6 23.0 11.0 17.0 17.0 5.9 18.0 24.4 16.1 21.5 18.5 19.7 23.7 21.6 36.1 20.5 21.5 18.6 25.2 18.0 18.2 17.9 33.0 15.9 12.9 10.3 17.8 9.3 15.3 16.0 7.9 24.4 15.7 44.1 6.6 27.3 4.5 16.8 31.6 0.0 27.7 61.8 26.8 11.6 20.7 17.9 29.2 28.6 29.2 17.8 16.4 4.3 19.5 16.3 21.9 33.3 26.3 17.7 26.2 24.6 20.5 13.0 18.2 12.9 16.0 15.6 26.2 14.2 38.0 24.5 21.3 6.8 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25617468-25786207 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 51.1;Ito cells: 82.9" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.3" "Lineage enriched" "Detected in many" 5 "T-cells: 8.3" "Cell line enhanced" "Detected in many" "AF22: 12.7;HSkMC: 47.0;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1200000 "Nucleoplasm, Vesicles" "HPA048352: AB_2680368" "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favorable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 4.6 4.5 4.2 3.0 3.8 0.0 2.2 9.9 8.8 8.6 3.6 1.2 6.6 2.5 2.4 3.9 7.3 3.4 5.2 3.2 10.3 12.1 3.2 4.0 4.2 7.1 0.7 4.4 7.8 8.3 7.2 1.2 1.8 7.5 0.9 2.7 1.9 8.0 6.0 7.0 3.1 1.0 10.7 3.2 4.3 4.0 1.0 0.6 1.1 1.6 0.8 8.3 1.1 0.0 0.1 12.7 2.7 9.5 7.4 3.7 0.1 2.4 0.6 0.2 0.2 0.0 0.1 0.1 0.9 1.7 0.1 1.2 0.1 0.2 4.0 0.5 0.2 0.2 0.0 1.1 2.1 5.3 47.0 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.5 0.0 0.6 0.0 2.3 3.3 0.0 0.1 0.2 7.8 0.2 0.1 0.2 7.5 0.2 0.3 2.0 0.6 2.4 1.0 1.5 0.0 0.0 0.7 8.6 0.3 14.0 0.0 0.0 1.9 4.5 0.6 0.4 1.6 0.7 0.6 1.0 0.8 0.4 3.6 1.6 0.6 1.0 8.3 4.8 1.1 0.8 1.3 0.4 0.8 1.1 3.0 2.7 1.9 2.9 6.0 19.1 6.4 5.1 2.7 7.9 21.0 51.1 8.3 8.3 0.5 0.3 11.1 0.0 0.0 3.4 1.0 9.9 2.6 2.3 37.6 19.1 20.6 2.9 82.9 16.5 0.9 25.0 3.6 1.7 0.0 0.0 20.6 2.2 0.0 20.8 12.8 4.5 6.5 3.1 0.2 2.0 4.5 35.7 5.3 0.0 1.3 MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689366-109869625 "Enzymes, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.8" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 88.9;Hepatocytes: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" NA NA 70000000 "Golgi apparatus" "CAB022377: , HPA026896: AB_1853512" "unprognostic (1.62e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (4.20e-2)" "unprognostic (3.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-1)" "unprognostic (6.77e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.11e-3)" "unprognostic (5.31e-3)" 7.6 17.5 10.9 7.7 21.8 5.7 7.4 1.9 13.2 8.4 11.2 46.8 2.4 17.2 9.2 1.8 7.7 6.2 10.6 4.2 11.7 4.8 9.5 20.7 8.5 7.8 29.9 10.4 7.5 16.7 20.1 3.4 8.7 19.8 4.7 11.9 5.6 9.0 6.0 8.7 7.0 14.4 11.2 23.1 6.9 8.9 7.5 30.6 15.0 9.0 1.8 7.8 10.9 6.2 3.3 2.7 5.8 6.7 0.9 5.5 1.6 7.3 6.8 8.5 3.6 16.4 14.5 32.0 16.4 27.1 9.3 16.9 8.0 11.9 5.3 10.6 21.3 6.5 8.7 4.5 17.0 20.5 5.7 3.5 10.8 5.1 7.3 9.2 4.9 5.9 12.3 7.0 14.9 19.9 11.5 18.4 5.4 2.9 31.1 22.0 3.6 9.1 1.3 6.1 4.9 2.5 3.6 13.3 23.5 7.5 11.7 1.2 1.1 7.7 6.9 4.6 9.6 6.8 4.3 19.6 18.5 8.2 10.0 10.6 16.6 21.5 4.5 14.2 6.3 10.2 5.8 2.9 0.9 3.0 3.8 1.9 3.3 4.5 4.9 2.7 2.9 5.5 4.8 2.1 0.9 6.7 2.5 4.1 1.6 10.9 21.8 1.9 13.2 11.7 4.8 29.9 10.4 19.8 30.6 6.0 6.7 28.2 9.3 15.9 0.2 5.9 40.8 9.4 7.9 29.6 0.0 16.0 1.7 21.5 7.3 22.4 45.5 23.3 30.1 88.9 21.8 26.3 14.0 113.4 16.8 0.0 23.7 41.7 62.5 4.9 9.2 22.8 25.3 25.2 37.1 7.5 30.3 28.1 6.3 21.4 0.3 19.4 16.0 5.5 19.1 20.7 19.8 15.8 41.2 17.8 MAN2A2 "HsT19662, MANA2X" ENSG00000196547 "Mannosidase alpha class 2A member 2" P49641 15 90902218-90922584 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Rod photoreceptor cells: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.4;neutrophil: 10.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 40.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077930 Approved "Cytoplasmic bodies" NA NA 30000000 "Cytoplasmic bodies" "HPA077930: AB_2732363" "unprognostic (5.17e-2)" "unprognostic (9.80e-2)" "unprognostic (2.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (3.41e-1)" "unprognostic (2.27e-1)" "unprognostic (5.06e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (8.95e-4)" "unprognostic (7.55e-3)" "unprognostic (1.13e-1)" "unprognostic (8.36e-2)" "unprognostic (2.33e-2)" 17.8 12.1 15.9 11.5 24.3 58.1 17.3 33.7 31.2 7.2 9.9 52.4 6.3 12.0 8.9 9.8 7.6 8.0 9.4 22.7 17.8 14.0 8.1 16.7 13.3 12.4 31.6 19.7 9.7 24.0 13.0 15.2 12.4 31.0 9.2 9.0 17.2 20.6 12.6 41.8 14.8 13.0 7.6 33.1 19.1 12.4 12.7 28.3 3.8 13.8 2.7 9.1 7.5 10.7 1.5 2.1 10.0 3.2 0.1 1.4 1.5 5.8 6.1 4.3 10.2 13.0 3.5 8.4 4.3 3.9 4.5 3.5 4.9 4.4 0.8 10.6 5.0 4.1 6.7 4.5 2.5 2.8 14.5 10.6 40.0 9.2 3.3 4.3 5.8 21.7 2.5 4.7 5.4 4.4 9.0 5.9 10.7 15.0 5.3 2.0 7.9 3.8 11.6 1.4 9.7 1.9 5.2 4.1 6.1 5.6 14.1 10.4 6.0 5.9 11.1 8.4 4.5 5.2 19.1 5.0 3.7 4.0 4.5 5.6 8.1 24.9 2.1 4.3 8.5 6.2 8.4 1.6 0.6 1.4 1.1 0.9 1.0 0.6 0.8 0.3 1.5 0.4 0.4 10.0 0.1 3.2 2.1 1.3 1.5 15.9 24.3 33.7 31.2 17.8 14.0 31.6 19.7 31.0 28.3 11.9 23.5 5.6 2.9 5.4 24.8 12.6 7.6 5.3 10.3 8.7 25.5 7.3 0.0 3.9 5.9 7.9 8.1 23.3 5.6 1.8 6.4 5.8 15.1 19.2 5.4 23.8 4.1 7.4 12.2 5.2 6.4 13.5 28.7 10.0 7.2 18.0 4.1 5.7 4.6 3.0 69.2 12.9 8.5 8.8 6.1 4.1 6.3 8.7 7.9 3.0 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 23.3;Macrophages: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 42.1;intermediate monocyte: 39.4;myeloid DC: 35.2;non-classical monocyte: 28.4;plasmacytoid DC: 41.9" "Group enriched" "Detected in all" 5 "dendritic cells: 41.9;monocytes: 42.1" "Low cell line specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3400000 "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 25.2 15.6 7.9 26.7 11.0 33.4 24.4 4.4 7.0 10.5 15.0 14.0 8.6 14.2 15.3 16.5 12.2 13.4 16.4 19.4 6.4 4.4 13.6 16.3 30.2 68.6 10.0 4.7 12.2 21.7 9.1 7.2 15.8 8.6 13.7 10.6 12.0 22.0 8.1 7.7 18.0 20.0 10.2 11.7 51.3 19.5 6.3 8.2 22.1 11.3 7.8 30.0 18.7 11.2 7.7 41.9 6.5 42.1 2.7 8.4 26.0 16.5 8.5 8.7 10.2 29.0 19.5 24.6 12.3 26.0 11.0 10.8 6.8 7.0 18.2 15.0 9.7 3.1 13.0 4.4 8.2 5.3 9.0 13.5 6.3 4.2 11.0 14.8 41.5 43.3 23.2 16.2 6.1 7.8 11.9 10.4 6.9 8.0 13.8 5.8 12.9 5.6 23.4 7.2 8.3 10.8 13.0 11.9 9.0 13.0 19.2 2.7 8.5 12.2 10.5 20.0 5.5 16.2 25.7 13.6 15.0 6.2 14.5 11.5 18.4 20.2 9.0 10.1 40.9 16.7 2.2 42.1 6.2 7.5 39.4 8.4 7.7 6.9 6.7 35.2 6.5 3.8 3.8 6.5 2.7 28.4 41.9 6.8 26.0 7.9 11.0 4.4 7.0 6.4 4.4 10.0 4.7 8.6 8.2 6.0 6.9 14.4 1.6 3.2 2.6 0.7 2.5 5.3 1.2 1.8 0.0 2.0 1.7 1.6 2.0 1.0 2.5 23.3 2.0 2.3 2.8 2.2 1.1 0.8 7.9 0.0 1.7 2.5 10.2 8.1 3.4 18.6 1.7 5.4 0.9 1.3 1.0 2.9 4.2 1.1 3.0 12.9 1.2 0.5 1.5 2.9 2.3 5.4 1.7 1.6 MAN2B2 KIAA0935 ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575175-6623362 "Enzymes, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Secreted to blood" NA NA 11000000 "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favorable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" 21.3 15.4 12.4 15.6 23.2 15.7 16.7 5.1 26.8 17.3 14.3 16.2 12.1 15.9 20.0 21.5 13.9 18.1 24.7 23.2 11.6 14.2 15.8 32.4 20.1 19.4 13.7 11.4 30.4 26.0 10.8 19.2 17.0 14.3 20.6 9.8 22.2 18.6 15.2 7.8 13.5 15.9 14.5 11.6 19.7 20.9 8.7 13.4 16.6 27.3 10.4 18.4 20.7 20.7 5.0 8.4 13.4 15.7 6.0 12.0 9.1 8.1 7.4 1.6 10.1 22.3 15.5 9.6 16.8 19.6 8.2 11.3 4.3 15.5 4.1 8.1 18.1 19.3 8.3 0.5 5.3 4.5 4.8 4.2 5.4 5.4 4.8 9.8 10.2 25.4 20.4 5.3 6.5 1.8 14.9 9.5 5.3 2.3 10.6 10.6 5.0 5.0 6.5 1.8 10.3 5.7 5.0 7.0 4.8 4.3 8.2 2.5 2.7 11.2 6.7 4.3 5.2 13.4 13.8 17.3 15.0 4.6 18.6 10.5 4.4 3.8 2.2 17.5 12.0 12.8 13.1 8.5 13.4 12.0 13.0 9.3 4.4 7.4 10.9 8.4 5.0 6.9 8.7 10.7 6.0 15.7 3.2 10.1 9.1 12.4 23.2 5.1 26.8 11.6 14.2 13.7 11.4 14.3 13.4 14.9 20.5 11.5 3.9 4.4 9.1 14.7 22.9 10.7 13.6 10.4 5.9 9.9 1.7 8.9 0.4 7.3 11.9 0.0 9.3 7.5 10.1 7.8 10.4 36.3 17.8 9.5 7.5 12.3 27.8 0.0 18.1 10.4 3.3 3.6 8.7 12.1 9.5 7.0 23.0 3.7 6.8 12.9 7.3 0.9 0.7 3.3 7.1 10.9 6.6 3.7 MAN2C1 "MANA, MANA1" ENSG00000140400 "Mannosidase alpha class 2C member 1" Q9NTJ4 15 75355207-75368630 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040627, HPA067407" Uncertain Enhanced Nucleoplasm NA NA 9000 Nucleoplasm "HPA040627: AB_10795490, HPA067407: AB_2685834" "unprognostic (4.68e-2)" "unprognostic (1.95e-1)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (3.85e-1)" "unprognostic (3.00e-2)" "unprognostic (1.26e-2)" "unprognostic (6.26e-2)" "unprognostic (2.47e-1)" "unprognostic (5.02e-2)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (4.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-3)" 29.9 28.8 22.6 20.4 26.0 30.0 24.6 27.5 25.5 25.1 25.1 26.8 23.8 22.9 27.8 27.5 20.2 24.2 23.3 28.2 18.3 12.9 22.9 21.4 25.2 17.0 23.0 28.3 32.8 22.3 28.2 30.6 22.4 18.3 24.9 14.2 30.8 25.6 20.2 37.9 30.9 27.7 20.0 15.0 28.1 23.0 28.8 19.9 21.0 34.7 15.3 19.5 21.1 21.3 2.3 15.7 2.6 16.2 3.9 7.3 8.5 5.5 13.3 11.1 8.0 12.7 11.0 13.8 12.9 12.2 6.8 5.7 9.2 19.1 2.7 7.6 9.4 6.2 17.2 6.1 8.7 4.4 15.2 13.4 17.5 25.2 9.1 18.8 11.2 2.8 13.1 8.8 6.4 8.1 14.4 15.8 8.0 10.0 14.4 5.5 10.8 5.5 12.7 4.7 6.6 5.6 7.8 5.6 16.6 8.9 25.9 6.6 12.0 8.2 12.5 5.8 8.3 12.4 13.1 30.9 14.3 10.0 9.9 12.7 14.4 3.5 4.4 9.2 12.9 14.2 2.6 13.3 2.0 7.2 16.2 6.8 2.3 5.3 5.2 15.7 2.0 7.3 5.1 1.4 3.9 12.4 6.4 7.0 8.5 22.6 26.0 27.5 25.5 18.3 12.9 23.0 28.3 18.3 19.9 20.8 52.5 12.9 13.4 11.9 32.1 2.0 5.1 16.0 18.2 8.7 51.1 14.5 3.3 9.4 8.2 17.2 21.3 0.0 7.7 8.8 15.0 13.8 31.1 21.5 17.5 27.0 32.8 33.2 37.8 10.6 21.6 24.1 15.1 19.8 21.0 18.6 9.2 14.4 11.7 12.3 52.0 25.8 10.4 18.6 10.9 7.4 17.7 12.7 20.7 11.9 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles "Intracellular and membrane" NA NA 12000000 Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 12.7 23.5 8.5 12.2 11.9 8.6 17.1 13.4 8.4 12.1 9.9 12.9 11.7 8.1 11.6 13.6 9.3 11.0 15.5 12.1 8.7 8.6 11.8 10.3 17.7 20.2 15.1 6.2 16.7 18.1 25.1 18.4 25.0 10.8 12.0 10.8 12.4 27.4 11.4 5.4 7.8 14.0 14.2 15.3 21.3 14.4 4.6 13.5 9.4 19.2 3.6 12.8 17.9 12.6 3.9 9.5 25.2 11.6 3.6 3.1 3.9 7.0 3.9 1.9 1.9 37.5 17.4 4.9 4.9 9.7 2.1 4.2 5.1 8.2 7.6 6.6 6.8 6.8 3.3 5.0 10.8 1.7 5.3 2.1 4.3 4.5 7.8 11.4 8.0 19.6 14.8 18.5 9.1 7.6 27.8 3.9 3.3 7.2 7.8 7.7 3.2 1.9 7.7 2.7 8.7 3.2 3.9 4.5 2.1 6.1 8.3 1.2 0.9 5.8 10.1 7.6 20.0 14.4 5.5 3.0 5.8 2.8 13.0 2.6 4.2 8.7 0.7 10.5 3.6 4.2 6.2 11.5 25.2 1.8 10.6 1.4 3.8 3.1 2.0 9.5 3.9 3.0 2.0 10.1 3.6 11.6 2.3 1.6 3.9 8.5 11.9 13.4 8.4 8.7 8.6 15.1 6.2 10.8 13.5 29.8 35.2 25.3 8.3 5.3 5.4 10.4 12.7 4.0 12.5 8.7 5.9 32.0 1.7 5.7 1.9 7.2 4.6 0.0 2.4 6.3 10.6 7.4 33.5 15.8 38.4 6.4 1.7 9.2 46.4 1.1 8.3 42.8 0.0 29.7 10.9 4.3 5.7 21.0 18.7 7.6 7.1 0.0 8.3 0.2 1.1 4.0 18.9 10.9 10.5 8.3 MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577543-95609457 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.9" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 53.1;Ito cells: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" NA NA 87000 "Golgi apparatus" "HPA011046: AB_1079303, HPA011069: AB_1079304" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "prognostic favorable (3.04e-4)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (2.98e-3)" "unprognostic (2.74e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.86e-3)" "unprognostic (5.18e-2)" "unprognostic (3.08e-1)" "unprognostic (9.68e-2)" "unprognostic (7.47e-2)" 18.0 8.1 6.0 6.7 6.9 2.4 14.4 8.3 6.0 9.6 9.5 5.0 5.8 7.7 7.5 8.2 11.5 7.2 7.1 9.3 6.5 6.2 14.6 44.9 9.8 12.3 8.9 6.7 10.4 8.0 10.9 13.5 7.4 7.8 9.2 8.0 4.5 8.1 7.6 3.8 5.9 9.5 6.0 11.6 13.2 10.7 7.1 6.9 17.9 11.7 5.9 9.7 11.2 7.5 6.6 3.4 8.5 5.7 3.8 10.4 3.3 3.8 3.3 12.5 10.1 20.8 24.5 4.8 10.8 9.9 6.3 9.5 3.7 9.7 7.4 13.5 7.0 9.5 6.4 8.6 7.2 14.5 12.7 7.7 10.0 3.1 6.0 7.2 13.1 8.9 24.2 8.4 7.5 5.3 9.1 14.7 7.7 15.4 17.2 13.4 2.7 7.6 5.6 1.8 10.2 3.3 9.2 12.5 11.0 9.6 6.7 10.1 5.4 6.1 4.4 3.8 9.3 7.0 12.3 13.3 6.3 4.5 11.3 10.6 12.9 7.5 9.2 11.3 11.5 14.3 8.5 3.3 1.9 4.8 5.7 6.8 6.6 5.9 5.5 3.4 3.3 6.9 4.6 0.7 3.8 4.9 1.3 10.4 3.3 6.0 6.9 8.3 6.0 6.5 6.2 8.9 6.7 7.8 6.9 11.9 6.7 4.5 4.6 6.5 8.3 3.2 7.6 10.7 7.9 12.2 3.9 4.5 5.0 3.3 12.0 6.3 2.5 0.0 6.2 4.6 5.2 3.2 2.3 53.1 9.2 11.1 1.7 36.8 9.1 10.0 5.5 6.9 8.5 2.8 4.7 9.1 3.3 3.5 14.9 8.6 4.8 12.9 5.3 6.8 12.5 6.0 1.1 6.4 5.2 3.0 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047233 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 98 "liver: 185.1" "Cell type enriched" "Detected in some" 68 "Hepatocytes: 541.9" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 4 "cerebellum: 1.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 7 "Hep G2: 20.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" NA NA 340000000 880000000 "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 0.3 0.2 0.3 0.4 0.3 1.8 0.3 1.7 0.5 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.3 0.1 0.3 185.1 0.3 0.6 0.3 0.3 0.5 0.4 0.0 0.3 0.3 0.3 0.3 0.0 0.3 0.7 0.3 1.4 1.4 0.5 0.3 0.3 0.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.4 1.2 1.2 0.2 0.8 1.3 0.0 0.5 0.3 2.9 1.6 0.0 0.1 0.5 0.8 0.0 0.0 0.0 1.3 1.1 2.4 0.7 0.0 0.6 0.7 0.0 0.0 0.0 0.6 2.3 1.4 2.6 20.5 0.0 2.2 1.7 0.0 0.0 0.1 0.0 2.0 0.0 1.9 0.8 0.5 0.0 0.6 0.6 1.2 0.4 0.2 0.6 1.8 1.0 0.5 0.0 1.4 1.8 0.7 0.9 0.5 0.5 1.8 0.6 1.3 1.2 0.9 0.6 1.0 0.6 0.8 1.1 1.7 0.6 1.9 0.4 1.2 0.2 1.1 0.7 0.1 1.0 0.7 0.9 0.8 0.5 1.4 1.3 1.3 0.2 0.8 0.2 1.2 0.1 0.0 0.3 0.3 1.7 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.0 0.0 3.4 0.2 0.8 0.0 0.4 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 541.9 0.1 0.0 0.0 8.0 7.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 157.1;Rod photoreceptor cells: 283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported NA NA "HPA056109: AB_2683040" "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favorable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 26.6 25.3 15.2 17.9 32.0 13.2 27.2 29.9 30.2 27.5 23.6 20.5 21.5 15.8 33.5 22.2 18.8 29.2 20.4 31.5 15.7 18.2 23.4 28.9 22.1 17.1 14.8 15.9 34.3 32.6 47.5 38.7 28.5 15.9 24.0 21.2 33.1 29.7 26.8 16.2 18.7 19.0 25.9 11.4 21.8 23.5 17.7 16.1 24.0 36.7 16.7 23.2 26.1 19.6 10.9 11.5 12.8 14.3 14.4 16.7 15.4 15.4 19.6 17.6 24.4 41.6 33.8 13.8 26.0 40.3 23.0 17.4 13.9 22.9 14.8 27.1 37.2 18.3 17.0 16.1 18.0 25.6 13.3 18.1 10.8 18.9 19.3 20.1 26.1 23.9 34.7 26.2 21.1 18.2 33.1 29.8 20.1 14.1 13.1 13.9 26.7 14.3 14.7 16.4 8.7 14.0 18.7 9.4 10.6 18.6 12.8 13.5 16.8 50.2 13.9 19.3 19.9 43.6 24.1 31.7 23.9 17.5 14.2 12.2 16.6 30.8 28.5 17.4 16.0 14.5 6.6 14.3 12.8 15.8 12.1 16.2 10.9 13.6 14.7 11.5 9.9 16.7 14.8 4.1 14.4 9.8 6.4 8.7 15.4 15.2 32.0 29.9 30.2 15.7 18.2 14.8 15.9 15.9 16.1 44.7 42.4 21.6 19.9 12.2 63.0 46.9 38.2 60.2 50.0 24.4 157.1 18.8 10.0 21.2 0.6 34.9 15.3 0.0 23.6 18.0 31.0 27.3 27.8 28.8 14.6 79.4 33.6 33.7 14.8 3.7 49.5 16.1 18.6 1.8 28.7 40.6 25.3 21.0 47.4 15.9 283.9 25.8 21.3 13.7 19.9 13.8 18.1 16.2 29.3 24.0 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839636-21885424 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 12.0 17.4 9.3 7.2 13.9 2.5 12.7 20.8 18.5 11.8 9.3 13.4 6.9 7.6 14.7 9.1 9.3 10.9 10.1 11.6 9.9 10.7 13.9 26.0 8.6 6.6 10.6 13.0 18.7 12.2 17.9 15.6 22.3 17.4 15.7 9.1 12.4 14.1 13.1 14.5 8.2 8.1 14.6 14.6 7.5 9.1 6.9 7.0 7.1 13.1 7.4 6.7 11.4 9.1 3.9 6.9 1.5 4.8 4.6 5.9 3.3 8.9 18.6 8.9 9.1 11.3 14.0 4.3 13.3 13.6 12.7 11.1 7.4 12.3 7.8 6.9 14.2 24.8 8.4 12.3 7.6 15.7 5.8 9.8 3.8 11.8 6.1 15.5 8.2 3.8 13.2 8.3 19.1 14.1 12.9 9.7 4.6 10.6 8.7 14.4 5.6 3.3 4.3 8.3 4.7 13.8 4.2 16.6 8.7 8.8 4.6 2.2 18.3 18.7 11.9 16.4 12.4 15.9 7.1 11.5 16.0 3.7 23.2 9.9 10.7 13.5 3.8 17.8 3.4 15.3 0.1 4.3 1.5 4.5 4.8 4.2 3.9 3.5 4.1 6.9 3.8 4.7 5.6 0.5 4.6 4.8 4.8 5.9 3.3 9.3 13.9 20.8 18.5 9.9 10.7 10.6 13.0 17.4 7.0 8.9 7.8 3.0 3.4 4.8 11.7 12.0 7.6 10.7 6.8 7.0 17.7 5.6 0.0 5.1 0.3 4.6 3.3 0.0 7.7 5.4 8.9 6.6 10.4 16.1 8.0 28.6 2.4 10.4 9.5 0.9 9.8 4.4 10.1 3.6 3.3 7.7 5.3 3.1 12.4 7.5 14.0 0.0 6.9 2.8 1.7 2.4 4.0 4.3 4.2 4.1 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598223-127622436 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 69.9" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 45.7;Extravillous trophoblasts: 22.4;Spermatogonia: 27.1;Syncytiotrophoblasts: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 8600 Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 2.9 3.7 2.1 24.3 4.0 32.5 3.5 6.7 3.2 4.7 7.1 3.3 2.2 4.7 4.7 5.9 11.2 4.8 5.4 3.6 2.0 2.3 3.9 3.4 3.4 14.6 2.2 3.5 5.1 3.0 2.4 2.4 26.4 3.0 3.2 6.0 2.5 4.7 1.9 7.0 6.0 7.1 2.9 2.9 13.3 3.8 20.3 3.9 69.9 4.1 16.6 20.7 3.4 5.1 10.4 3.6 0.9 1.4 5.8 10.6 3.4 25.1 21.4 23.5 20.5 1.4 3.0 23.0 13.2 8.5 26.6 29.0 35.5 16.7 27.1 12.9 6.5 22.8 20.3 41.9 15.2 16.6 22.4 26.2 44.9 28.7 25.8 0.9 41.9 19.6 1.6 1.7 18.0 2.7 3.2 8.3 29.6 22.3 24.9 9.8 33.3 38.8 30.7 34.4 21.6 18.9 43.6 33.7 38.8 5.5 19.5 29.3 22.2 33.9 10.1 3.5 9.9 21.7 32.9 4.2 20.7 17.7 25.5 17.8 25.8 29.2 67.4 14.3 31.7 7.9 0.0 0.6 0.2 4.7 1.4 5.9 10.4 4.1 5.5 2.8 9.2 3.9 5.0 0.9 5.8 0.3 3.6 10.6 3.4 2.1 4.0 6.7 3.2 2.0 2.3 2.2 3.5 3.0 3.9 3.0 1.3 6.7 1.7 4.0 2.2 7.6 0.0 10.7 5.7 0.0 0.0 45.7 0.0 4.1 0.7 1.7 1.0 0.0 1.6 22.4 3.3 0.7 1.1 1.7 15.2 0.0 3.5 1.3 1.6 0.7 1.7 1.6 1.7 15.4 5.1 1.5 1.7 0.0 1.4 0.5 1.7 0.0 2.8 6.2 27.1 2.6 28.0 3.2 12.0 0.6 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264009-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 82.5" "Cell type enhanced" "Detected in many" 5 "Cytotrophoblasts: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Supported Nucleoplasm NA Yes 29000 Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.34e-2)" 17.3 10.9 8.5 29.7 10.5 22.3 15.3 10.7 9.7 15.9 17.2 9.5 20.2 9.0 21.2 13.0 21.7 15.5 15.8 15.4 7.4 6.6 16.1 12.6 13.7 30.1 8.9 5.8 20.0 13.8 16.0 7.4 24.7 10.0 15.9 19.2 12.7 12.6 23.4 12.1 15.0 17.8 17.7 9.5 23.2 15.3 16.1 10.5 82.5 12.9 20.1 35.7 19.1 15.3 21.1 12.9 11.4 13.3 22.2 29.4 18.6 30.2 20.1 35.1 33.0 7.6 6.8 23.0 22.5 17.3 38.4 39.4 41.1 16.5 33.0 22.6 13.1 25.1 24.1 46.2 27.5 38.8 37.1 43.7 62.4 40.4 57.9 2.0 61.2 25.6 4.1 6.4 28.2 7.9 9.4 19.5 40.0 50.7 76.2 19.7 19.9 61.6 47.3 29.1 60.3 14.2 54.7 53.7 44.1 17.0 32.2 35.6 27.3 23.6 13.6 20.4 51.4 26.8 43.4 10.0 26.2 28.2 27.1 33.5 22.6 25.8 58.8 22.5 53.1 30.7 11.1 8.0 11.4 22.9 13.3 19.7 21.1 23.3 23.0 12.9 19.2 22.6 24.0 1.1 22.2 7.4 8.3 29.4 18.6 8.5 10.5 10.7 9.7 7.4 6.6 8.9 5.8 10.0 10.5 20.8 10.5 30.5 14.0 17.1 13.8 13.9 12.7 22.7 20.5 21.0 3.9 85.3 11.6 21.3 0.6 24.8 4.9 23.3 17.7 53.2 16.0 7.5 36.9 9.3 30.8 0.0 7.0 14.7 8.9 2.3 25.0 13.8 6.8 10.8 16.7 19.0 13.0 10.5 19.8 6.5 11.2 6.5 24.7 21.7 59.4 8.8 22.9 27.7 31.0 11.2 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 117.9;Late spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: AB_2673712" "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favorable (2.19e-4)" "prognostic unfavorable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 4.9 8.7 6.7 18.4 12.6 33.1 9.3 13.9 14.8 6.7 11.9 6.9 3.6 8.3 4.7 7.8 21.6 5.9 6.8 8.3 6.6 7.1 8.0 6.6 4.4 20.3 5.9 7.7 5.3 5.5 4.3 4.1 29.2 7.7 4.2 13.2 5.3 9.0 3.1 8.7 16.2 10.3 5.9 6.4 10.1 6.3 39.0 4.1 56.6 4.0 21.8 23.7 8.0 9.5 5.1 4.9 3.4 4.3 4.9 12.9 4.5 34.5 21.5 39.9 14.6 3.9 6.9 17.6 26.4 17.3 33.3 37.7 22.8 31.5 37.5 14.8 13.1 25.0 25.5 50.3 21.4 37.6 11.8 33.2 64.3 25.8 25.3 1.1 34.3 14.1 4.1 4.3 26.5 9.5 5.1 11.7 25.3 35.4 31.2 22.9 21.4 75.8 25.0 43.3 41.1 9.3 48.2 31.3 24.4 12.0 31.0 38.4 18.4 53.4 22.3 7.9 23.8 26.6 18.1 7.8 25.4 24.7 28.5 24.2 10.3 24.6 76.5 20.4 31.9 22.7 3.4 2.1 1.5 5.5 3.7 2.7 5.1 5.0 6.8 4.9 2.1 4.6 3.4 0.1 4.9 4.3 1.7 12.9 4.5 6.7 12.6 13.9 14.8 6.6 7.1 5.9 7.7 7.7 4.1 0.0 4.6 3.0 9.5 19.3 11.6 22.4 0.0 17.4 10.3 5.2 9.8 26.7 3.3 6.0 117.9 5.2 5.0 46.7 5.2 33.9 7.4 4.3 1.1 3.4 10.4 15.9 6.4 1.3 3.5 57.7 4.9 9.9 3.3 2.8 9.6 6.5 4.1 3.5 2.8 2.2 15.3 0.0 8.0 45.2 31.3 16.7 24.9 3.8 20.2 8.2 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400063-35425430 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.0;lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" 11 "Cytotrophoblasts: 115.2;monocytes: 225.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 12.1 4.9 6.1 27.5 9.0 57.0 9.1 6.7 5.7 10.4 11.5 12.3 5.0 9.5 10.8 10.8 15.8 8.7 9.4 5.2 4.4 3.4 6.8 8.0 9.3 31.1 8.8 3.7 17.9 10.8 6.2 3.6 19.3 5.8 7.2 8.3 6.5 8.9 5.1 8.8 10.3 16.7 6.0 7.8 31.2 8.4 16.4 8.8 60.6 9.0 17.7 33.0 8.7 9.6 46.8 30.9 19.0 26.0 21.3 32.9 24.0 39.3 28.6 22.6 23.0 2.2 4.5 19.9 26.3 14.0 39.4 37.5 19.0 19.7 26.1 15.3 13.4 16.3 19.7 22.6 20.9 12.6 21.0 41.5 37.2 28.7 38.0 0.8 76.8 33.7 2.4 1.9 23.5 6.4 3.6 17.4 23.9 23.0 39.0 14.9 32.5 62.5 25.6 30.1 26.9 17.0 70.8 32.1 32.8 7.7 22.9 17.5 18.6 36.2 14.5 8.1 12.4 15.2 29.4 10.3 39.8 30.2 24.7 27.1 21.7 26.8 49.1 25.8 29.1 30.3 19.0 20.7 14.5 18.4 24.1 13.1 46.8 16.1 19.4 27.1 37.0 13.1 14.8 9.9 21.3 26.0 30.9 32.9 24.0 6.1 9.0 6.7 5.7 4.4 3.4 8.8 3.7 5.8 8.8 6.0 8.2 53.6 8.0 9.4 1.5 3.4 12.7 5.3 4.5 7.0 0.0 115.2 5.0 14.8 1.9 7.5 3.8 70.0 11.1 61.5 6.2 3.3 15.0 5.1 47.1 1.6 3.4 13.5 21.1 3.6 10.0 25.5 6.8 225.4 9.2 4.5 9.4 7.0 5.6 3.7 3.2 19.4 6.4 11.2 52.2 5.5 68.8 20.8 32.2 4.7 MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876426 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 66.3" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 46.7;Spermatogonia: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm NA Yes Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" 11.3 6.3 7.2 17.7 8.4 23.1 9.5 12.3 9.4 9.1 11.9 5.1 2.9 8.7 10.4 8.8 12.6 8.7 7.6 6.0 5.0 5.5 6.8 7.0 8.5 23.9 4.9 8.0 10.9 4.3 6.2 3.4 10.9 5.9 8.6 12.2 6.2 6.9 6.7 8.2 8.9 16.7 10.4 7.2 14.1 8.0 13.2 3.7 66.3 5.1 11.4 27.5 10.8 9.8 5.5 9.4 5.3 4.0 7.0 13.9 5.6 23.3 14.3 31.3 19.9 6.7 8.8 12.3 17.0 12.9 19.8 22.1 29.3 17.9 40.8 12.5 12.3 8.7 13.9 31.6 15.5 21.2 20.9 21.8 40.5 21.3 9.2 3.1 48.5 18.1 5.2 2.0 14.4 4.4 4.0 13.4 32.2 28.9 34.5 14.5 23.8 59.2 35.7 28.2 20.6 14.4 29.4 37.5 37.3 9.9 20.6 19.7 16.8 22.4 10.7 10.7 23.4 12.3 30.6 6.6 13.8 11.5 14.8 12.8 20.7 33.7 53.7 19.3 37.2 16.4 5.3 1.4 0.9 7.6 4.0 7.1 5.5 10.5 9.2 4.6 3.2 9.6 11.8 0.8 7.0 3.6 9.4 13.9 5.6 7.2 8.4 12.3 9.4 5.0 5.5 4.9 8.0 5.9 3.7 0.0 2.4 2.2 3.8 6.0 2.2 3.2 2.5 4.0 6.8 3.5 0.0 26.1 0.0 4.4 2.1 7.1 1.3 46.7 5.8 20.9 11.3 1.5 9.2 3.0 20.4 3.2 2.4 9.8 4.0 1.6 8.6 5.8 5.0 3.6 9.2 2.3 2.8 3.5 15.9 1.0 0.5 0.0 4.2 15.6 41.4 3.6 8.9 17.5 9.7 1.0 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm NA Yes Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 8.6 5.2 17.5 13.6 21.7 37.3 11.2 20.0 20.6 8.2 14.2 19.2 15.0 10.4 16.0 6.3 10.7 8.6 9.9 5.1 18.1 12.4 5.5 8.5 7.4 22.4 23.7 9.5 12.6 13.1 7.5 10.3 10.7 15.5 10.0 15.7 7.2 9.2 9.2 11.5 10.1 10.3 11.7 23.5 10.7 7.8 14.9 22.3 7.5 9.4 4.1 28.2 10.3 10.0 7.3 5.7 1.9 5.7 7.6 9.0 6.0 24.9 28.8 31.8 24.0 3.1 4.1 16.3 15.2 18.4 42.5 45.3 22.0 26.4 42.3 14.5 10.8 27.1 19.8 46.7 22.1 35.9 21.6 39.9 26.9 16.2 15.2 1.7 45.7 17.5 2.8 4.2 31.1 18.7 5.4 16.1 24.4 51.5 34.7 21.5 53.3 77.6 18.7 27.9 23.2 20.9 41.8 46.7 51.6 8.2 15.1 20.8 31.7 24.0 22.3 7.5 18.6 10.2 19.2 6.8 16.0 29.1 31.4 30.1 14.5 24.8 76.1 11.1 36.7 28.6 1.8 2.5 1.9 8.1 4.1 6.2 5.3 5.7 7.9 5.5 7.3 5.9 5.7 1.6 7.6 5.7 5.7 9.0 6.0 17.5 21.7 20.0 20.6 18.1 12.4 23.7 9.5 15.5 22.3 8.9 17.0 23.7 20.7 41.4 8.7 7.9 15.3 24.1 9.1 3.5 13.7 90.8 8.3 17.6 40.0 14.5 15.8 70.0 22.4 78.1 17.3 11.3 24.2 10.4 34.4 6.4 16.7 8.0 10.8 22.7 19.5 16.5 18.6 17.2 34.7 10.1 16.0 20.1 14.5 9.1 11.9 12.9 22.7 83.2 67.3 30.9 60.2 28.7 60.9 12.3 MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Spermatocytes: 43.2;Spermatogonia: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045141, HPA066433" Supported Nucleoplasm NA NA Nucleoplasm "HPA045141: AB_2679230, HPA066433: " "unprognostic (6.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.43e-1)" "unprognostic (2.22e-3)" "unprognostic (1.90e-1)" "unprognostic (5.78e-2)" "prognostic unfavorable (9.30e-8)" "unprognostic (5.21e-2)" "unprognostic (5.14e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (6.74e-2)" "unprognostic (1.11e-2)" "unprognostic (5.53e-2)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (3.47e-1)" 4.9 5.4 7.3 11.0 7.6 11.2 9.3 17.9 12.7 5.4 6.2 3.1 12.0 5.4 5.9 3.9 6.6 4.3 2.7 11.3 4.8 2.2 4.3 3.1 6.3 9.6 10.6 5.1 5.0 5.6 5.1 4.8 5.4 7.1 5.9 6.0 3.5 5.1 7.2 11.2 6.1 6.1 7.0 8.3 6.1 5.6 21.9 7.7 8.8 4.4 7.0 9.5 6.0 6.1 1.8 1.7 3.3 0.7 1.9 3.0 0.4 19.1 15.0 12.9 13.0 3.4 4.2 11.5 15.7 6.4 12.4 14.9 16.3 12.1 19.5 4.7 5.2 22.3 20.6 21.4 12.4 22.3 5.3 8.7 21.6 7.2 15.9 0.5 22.7 3.4 1.9 2.0 20.8 8.6 3.2 5.7 12.5 22.0 19.3 12.6 5.4 11.7 11.9 17.3 11.8 8.8 14.3 21.9 7.9 3.1 7.6 9.6 10.2 16.0 17.9 9.6 14.5 11.5 8.1 3.8 21.9 18.3 11.8 22.8 8.3 20.7 33.2 4.4 14.7 18.0 3.3 0.5 1.7 1.8 0.5 3.0 1.8 1.1 2.1 0.1 1.7 1.1 1.7 2.1 1.9 0.7 1.7 2.0 0.4 7.3 7.6 17.9 12.7 4.8 2.2 10.6 5.1 7.1 7.7 0.0 4.1 10.0 2.6 2.1 6.9 8.5 7.6 4.0 2.3 12.2 15.7 5.2 0.0 1.2 6.5 3.0 3.8 0.0 2.3 4.7 2.7 4.2 1.1 1.6 3.6 6.4 4.1 1.8 2.1 2.3 3.4 3.5 1.7 0.0 2.9 4.0 2.7 3.5 2.8 2.4 10.7 6.5 2.7 43.2 32.6 2.3 3.3 3.9 5.2 1.8 MCM9 "C6orf61, dJ329L24.3, FLJ20170, MCMDC1, MGC35304" ENSG00000111877 "Minichromosome maintenance 9 homologous recombination repair factor" Q9NXL9 6 118813442-118935162 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031137 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA031137: AB_10602027" "unprognostic (3.11e-2)" "unprognostic (1.99e-1)" "unprognostic (4.33e-3)" "unprognostic (2.90e-1)" "unprognostic (2.78e-2)" "unprognostic (2.82e-1)" "unprognostic (3.00e-2)" "unprognostic (2.29e-1)" "unprognostic (3.61e-2)" "unprognostic (7.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (8.30e-2)" "unprognostic (2.16e-1)" "unprognostic (3.95e-1)" "unprognostic (2.26e-1)" "unprognostic (8.79e-2)" 8.6 7.2 5.9 11.9 8.4 14.5 17.7 5.2 6.9 9.4 11.2 8.2 9.8 7.3 9.0 16.0 10.2 8.6 8.2 6.6 5.9 4.0 9.3 7.6 15.6 12.1 11.5 4.7 8.7 12.2 11.9 11.2 13.8 6.3 10.5 8.4 7.0 11.8 8.7 4.2 9.8 12.6 10.9 5.7 10.2 7.3 7.9 8.1 27.0 13.1 7.1 9.9 9.6 10.5 3.1 5.2 8.0 5.3 10.2 6.4 3.9 4.6 7.4 11.9 12.8 5.4 5.3 9.1 4.4 7.9 6.5 8.3 6.1 8.4 14.1 5.5 7.6 4.3 14.0 8.3 4.8 9.2 8.3 11.4 11.2 8.8 5.9 3.2 12.0 7.6 5.8 5.7 6.7 7.7 4.1 6.2 8.8 13.5 6.5 4.3 9.8 10.6 9.7 5.8 7.7 3.4 8.4 7.5 3.7 6.6 9.3 10.3 7.4 7.8 5.7 4.1 3.2 8.5 17.0 6.3 5.2 4.6 3.7 6.5 8.7 7.2 16.7 6.6 9.8 6.0 7.2 4.5 8.0 4.9 5.3 3.8 3.1 3.0 5.0 5.2 3.0 3.6 3.5 5.4 10.2 3.2 3.7 6.4 3.9 5.9 8.4 5.2 6.9 5.9 4.0 11.5 4.7 6.3 8.1 6.0 4.1 4.4 3.1 2.6 3.5 3.9 2.5 12.0 4.5 7.0 9.8 9.1 3.3 2.3 1.5 4.4 5.1 0.0 2.5 2.9 2.8 3.4 6.9 2.4 3.0 1.6 6.9 3.7 5.3 1.9 3.4 4.5 0.0 2.8 5.9 2.1 2.1 5.8 3.9 2.9 5.4 0.0 2.1 4.8 2.7 1.8 6.1 5.3 4.1 4.1 MDP1 "FN6Pase, MGC5987" ENSG00000213920 "Magnesium dependent phosphatase 1" Q86V88 14 24213937-24216070 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003064, HPA070338" Uncertain Approved Nucleoplasm NA NA 34000 Nucleoplasm "HPA003064: AB_10602350, HPA070338: AB_2686256" "unprognostic (2.70e-1)" "unprognostic (3.68e-1)" "unprognostic (2.51e-1)" "unprognostic (2.11e-1)" "unprognostic (3.09e-1)" "unprognostic (5.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "unprognostic (8.02e-2)" "unprognostic (2.00e-3)" "unprognostic (1.02e-1)" "prognostic favorable (5.96e-4)" "unprognostic (6.39e-2)" "unprognostic (1.32e-1)" "unprognostic (3.82e-1)" "unprognostic (3.19e-2)" 12.2 17.6 18.5 8.3 15.0 8.1 18.7 18.6 18.3 13.3 10.2 13.1 21.0 6.7 10.6 19.0 8.9 14.3 12.0 17.8 13.8 13.9 16.6 14.7 8.7 13.5 15.1 14.5 12.9 20.2 14.8 18.3 9.4 16.6 13.3 8.6 13.5 14.3 16.3 11.4 10.6 9.8 10.9 13.9 10.4 10.0 6.6 17.0 14.3 14.6 10.6 10.8 10.0 9.6 10.1 23.0 12.2 11.1 9.0 11.9 7.9 3.1 7.9 6.0 3.9 6.0 5.6 0.2 3.4 7.4 6.9 7.2 4.2 9.1 12.8 8.8 3.5 2.1 3.1 2.9 6.8 4.3 4.3 3.2 4.9 2.9 9.6 5.8 6.2 3.6 3.9 6.3 4.2 8.0 7.1 4.9 9.3 1.5 9.6 6.2 17.2 8.8 10.2 1.7 6.3 14.2 6.3 4.2 10.1 6.7 4.6 7.4 7.2 5.4 11.6 7.2 3.4 7.0 3.3 2.9 7.6 7.3 3.2 3.4 15.6 6.2 9.3 7.1 3.1 5.8 3.1 10.9 12.2 6.3 11.1 5.9 10.1 8.1 7.3 12.4 9.5 9.9 8.2 3.8 9.0 9.4 23.0 11.9 7.9 18.5 15.0 18.6 18.3 13.8 13.9 15.1 14.5 16.6 17.0 6.0 11.7 7.5 2.8 4.0 3.4 0.0 5.1 21.4 0.0 5.2 0.0 3.1 11.6 10.4 3.0 5.2 8.1 0.0 17.0 4.4 5.6 2.4 4.7 5.0 7.0 3.2 11.1 6.2 2.2 2.9 5.8 11.0 16.9 29.7 11.1 3.1 12.6 2.9 7.1 15.7 2.7 12.9 7.2 1.9 3.2 4.0 2.1 5.1 10.7 2.0 MEP1A PPHA ENSG00000112818 "Meprin A subunit alpha" Q16819 6 46793390-46839782 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 52 "intestine: 243.0" "Group enriched" "Detected in some" 4 "Enterocytes: 391.5;Paneth cells: 129.6" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 38.6" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "myeloid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 3.1;CACO-2: 7.1;Hep G2: 1.9;NB-4: 3.1;RPMI-8226: 3.5;SH-SY5Y: 2.2;U-2197: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025163, HPA029416" Enhanced NA NA 990000 "CAB025163: , HPA029416: AB_10600823" "unprognostic (1.83e-1)" "unprognostic (2.81e-4)" "unprognostic (2.03e-1)" "unprognostic (8.53e-2)" "unprognostic (8.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (5.27e-4)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.91e-2)" "unprognostic (4.70e-3)" "unprognostic (1.68e-1)" 0.1 0.1 0.1 4.7 0.1 0.0 0.1 0.1 0.1 0.1 100.5 0.1 0.1 51.7 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 19.8 0.1 0.2 0.1 0.1 0.1 243.0 0.2 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 0.0 3.5 0.0 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 391.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.9 0.0 0.0 4.7 0.0 0.0 0.0 0.0 61.3 0.0 0.0 129.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 28.3 0.0 MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "intestine: 241.5" "Group enriched" "Detected in some" 6 "Early spermatids: 2.1;Enterocytes: 6.3" "Group enriched" "Detected in some" 5 "pancreatic cancer: 3.0;stomach cancer: 0.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA029119 Enhanced "Secreted to digestive system" NA NA 120000 "HPA029119: AB_2672913" "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 0.1 78.8 0.0 0.0 54.5 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 241.5 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.1 0.4 0.3 0.3 0.0 1.4 0.5 0.2 0.0 0.0 0.5 0.6 0.0 2.1 1.0 0.3 0.3 0.1 0.6 1.4 1.7 0.5 0.0 0.8 0.2 0.0 0.0 0.0 0.8 1.0 1.1 0.7 0.6 0.4 1.3 0.3 0.0 0.7 0.0 0.1 0.7 0.5 1.6 1.1 0.2 0.0 1.9 1.3 4.1 1.3 0.5 0.0 1.8 1.8 2.9 0.0 0.7 10.6 2.4 0.8 0.2 0.3 0.3 0.4 3.1 0.9 1.4 0.8 3.4 0.0 0.6 2.3 0.5 2.6 0.0 0.5 0.0 0.3 0.3 1.0 0.1 1.3 1.1 0.7 1.4 0.4 0.1 1.2 0.3 0.2 0.0 0.1 0.2 0.5 0.5 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995620-99062813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Early spermatids: 345.0;Late spermatids: 1171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 11000 Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: AB_2675777, HPA037998: AB_2675778" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "prognostic favorable (7.22e-4)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.72e-4)" "unprognostic (5.50e-2)" "unprognostic (8.51e-2)" "unprognostic (1.15e-3)" "prognostic favorable (9.31e-4)" 12.1 8.3 10.0 16.0 10.1 11.8 18.6 9.2 13.8 16.0 17.9 7.0 22.9 13.4 24.1 25.9 37.2 14.0 12.3 27.9 9.5 7.1 14.3 13.7 10.7 12.6 7.9 9.8 11.3 13.0 7.8 14.4 9.2 9.9 19.1 19.3 7.5 19.0 21.5 27.2 16.4 15.2 27.8 10.1 13.9 11.6 46.8 8.1 27.0 10.8 21.8 19.1 36.6 22.6 12.7 11.7 10.4 11.1 12.5 19.2 10.8 21.7 21.5 18.9 20.3 15.0 24.1 21.0 31.2 20.1 26.7 25.5 24.1 32.5 32.3 12.5 25.2 16.0 21.9 33.1 31.2 37.1 22.5 15.8 28.8 15.7 25.9 16.3 38.9 24.2 17.3 22.8 22.7 24.1 20.8 21.9 18.3 22.5 19.5 28.5 16.6 34.1 18.6 23.2 37.1 17.5 22.4 29.5 17.2 42.9 28.2 25.9 15.3 10.4 32.4 12.3 22.1 12.4 14.9 17.8 21.6 27.5 19.8 27.2 14.2 19.9 25.5 18.6 20.0 21.4 10.4 9.4 4.2 14.9 11.1 19.2 12.7 15.4 14.5 11.7 10.1 15.1 13.5 2.3 12.5 10.7 5.8 13.4 10.8 10.0 10.1 9.2 13.8 9.5 7.1 7.9 9.8 9.9 8.1 38.7 10.5 13.7 44.1 37.7 4.6 49.8 20.4 18.7 17.0 14.0 2.0 22.0 11.6 26.9 345.0 13.5 29.0 0.0 25.4 55.9 12.3 21.8 3.5 16.4 15.6 3.2 7.5 16.5 19.6 1171.9 17.8 14.6 15.1 6.4 25.2 8.3 22.3 34.2 21.2 22.9 3.5 25.8 22.1 15.1 46.4 33.9 6.4 15.2 32.6 39.6 METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999583-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Leydig cells: 31.1;Peritubular cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299" Uncertain Uncertain Vesicles NA NA Vesicles "HPA030298: AB_2673419, HPA030299: AB_10602421" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (5.83e-2)" "unprognostic (2.54e-2)" "unprognostic (7.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.07e-2)" "unprognostic (4.55e-1)" "unprognostic (7.07e-2)" "unprognostic (2.64e-2)" "unprognostic (8.19e-2)" "unprognostic (2.53e-3)" "unprognostic (3.44e-3)" "unprognostic (3.06e-2)" "unprognostic (5.48e-3)" "unprognostic (2.92e-2)" 7.1 7.5 7.2 8.0 8.4 6.3 8.2 6.7 9.2 6.5 6.1 9.6 6.5 5.0 9.0 6.4 5.2 10.3 4.5 6.4 6.0 4.9 5.4 8.3 3.6 8.1 9.3 7.1 18.9 23.8 5.5 13.8 4.1 8.6 8.3 7.1 7.3 9.7 10.3 13.8 7.1 5.9 10.0 7.2 8.6 6.3 5.9 9.5 2.1 5.6 6.3 6.7 5.4 5.7 2.5 0.5 0.2 1.2 1.2 3.6 0.7 3.3 2.7 3.9 13.2 5.8 7.6 8.1 3.9 3.9 6.2 4.0 6.1 4.5 1.7 7.1 4.1 6.4 6.2 8.6 6.8 6.4 6.0 10.3 9.5 7.0 8.1 6.2 5.6 2.5 5.8 10.7 6.2 10.0 5.4 3.5 6.6 13.7 4.9 4.7 4.1 3.2 7.6 7.2 9.6 3.3 7.2 3.4 3.0 4.4 4.7 8.2 3.2 2.7 5.6 9.6 3.6 6.5 7.6 4.1 8.0 6.3 4.8 3.7 6.1 5.5 3.8 5.7 11.2 7.6 0.0 0.2 0.0 1.3 1.2 0.6 1.2 1.9 0.7 0.5 2.5 1.9 3.6 0.2 1.2 0.2 0.0 1.4 0.7 7.2 8.4 6.7 9.2 6.0 4.9 9.3 7.1 8.6 9.5 0.0 5.8 5.8 8.8 4.9 4.9 3.4 5.1 1.4 1.2 3.5 2.0 3.9 6.6 2.1 0.6 3.8 0.4 0.0 2.9 3.9 8.0 4.7 4.6 6.0 3.4 4.8 0.0 6.2 2.8 0.9 31.1 1.3 5.0 0.0 2.6 3.2 1.8 0.0 24.8 3.8 4.9 12.9 5.6 6.9 10.6 5.0 1.6 6.9 5.2 4.1 METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" NA NA 22000 "Plasma membrane, Cytosol" "CAB013025: AB_2533993, HPA019095: AB_1853823" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.51e-6)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" 24.2 36.4 25.8 49.9 33.7 39.1 25.1 25.9 32.3 23.9 26.2 16.3 102.5 16.6 28.7 25.4 30.1 22.5 21.7 30.7 29.6 24.0 26.0 46.8 22.1 32.6 29.1 23.4 29.4 31.9 21.0 36.1 25.1 42.9 24.2 24.0 10.1 22.1 140.7 94.4 28.7 19.7 26.1 48.2 25.2 22.2 26.3 27.7 32.1 24.1 29.0 55.2 33.4 37.3 39.4 31.8 21.3 27.1 25.7 32.0 16.2 33.9 28.6 30.6 23.8 18.7 30.0 23.6 33.5 23.4 33.0 23.5 41.5 16.3 98.8 21.1 23.9 19.2 21.9 34.4 25.6 38.0 23.5 29.7 44.2 21.8 29.2 19.9 54.7 21.7 25.9 27.4 31.2 30.6 39.6 35.1 34.1 57.2 11.2 24.4 22.3 40.5 37.4 37.5 19.6 42.8 31.9 26.5 32.4 22.6 36.0 23.8 31.3 29.7 24.3 29.3 27.6 29.3 26.0 30.1 19.0 18.4 21.2 35.3 16.2 42.1 105.9 10.8 30.9 23.8 21.3 27.1 11.1 23.8 19.1 29.2 39.4 26.7 26.6 24.4 37.6 32.0 29.7 1.2 25.7 22.3 31.8 25.3 16.2 25.8 33.7 25.9 32.3 29.6 24.0 29.1 23.4 42.9 27.7 262.0 228.6 96.8 102.9 207.2 62.7 117.4 91.7 104.4 160.3 275.7 62.8 125.5 139.3 94.7 135.8 104.6 80.2 256.9 126.2 136.4 102.7 68.6 119.0 278.9 86.9 71.5 88.0 102.5 122.4 83.3 92.9 93.2 87.7 80.2 109.6 67.6 105.7 83.4 100.4 81.6 68.7 97.0 97.6 340.7 217.0 187.9 143.8 93.5 118.5 90.7 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 155.5" "Cell type enhanced" "Detected in some" 24 "Early spermatids: 50.7;Late spermatids: 90.5;Proximal tubular cells: 18.9" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "neutrophil: 14.1" "Lineage enriched" "Detected in single" 104 "granulocytes: 14.1" "Cell line enhanced" "Detected in some" "A549: 3.7;BJ hTERT+: 3.3;HL-60: 5.5;U-937: 8.7;WM-115: 2.1" "Region enriched" "Detected in single" 12 "olfactory region: 3.1" HPA002270 Enhanced NA NA 68000 "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 0.9 0.2 0.3 0.8 0.2 6.9 0.3 0.2 0.2 0.2 59.4 0.1 7.6 25.2 0.2 36.0 0.2 1.0 0.1 0.3 0.2 0.2 8.7 0.4 2.1 0.1 0.3 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.0 0.1 0.2 3.2 0.2 0.1 155.5 0.1 0.3 8.3 0.7 4.3 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 3.7 0.2 0.1 0.0 0.0 0.5 0.1 3.3 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.4 0.1 0.3 0.0 0.1 0.0 8.7 2.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.1 0.0 4.5 0.0 0.0 0.0 0.0 1.1 0.0 2.7 2.3 12.2 0.0 0.0 1.7 0.0 50.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 90.5 0.6 1.8 0.0 0.0 0.4 0.5 0.2 0.0 0.4 18.9 0.0 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.2 0.2 MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111749-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 61.2;pancreas: 15.6;salivary gland: 35.4" "Group enriched" "Detected in some" 10 "Early spermatids: 21.0;Late spermatids: 12.0" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.1" "Group enriched" "Detected in some" 8 "OE19: 5.5;RH-30: 4.0" "Low region specificity" "Detected in many" HPA055697 Enhanced Approved Vesicles,Cytosol NA NA Vesicles Cytosol "HPA055697: AB_2682890" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" 0.2 0.1 0.1 2.5 0.1 0.2 1.3 0.1 0.1 0.1 28.8 0.0 0.0 15.0 0.1 0.4 0.1 0.3 7.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.1 15.6 0.0 0.1 0.0 0.1 0.1 1.4 0.7 35.4 0.0 0.1 0.2 61.2 0.0 0.5 1.5 0.7 1.0 0.0 0.0 0.1 1.7 0.8 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.5 0.0 0.0 4.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MGEA5 "MEA5, NCOAT, OGA" ENSG00000198408 "Meningioma expressed antigen 5 (hyaluronidase)" O60502 10 101784443-101818465 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol NA NA Cytosol "HPA036141: AB_10672079, HPA076501: AB_2686802" "unprognostic (4.34e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (4.63e-1)" "unprognostic (2.06e-1)" "unprognostic (2.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-3)" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.90e-1)" "unprognostic (9.23e-3)" 29.5 17.5 51.9 27.4 54.4 49.3 35.5 58.9 51.4 24.5 27.0 29.0 20.9 17.6 29.9 36.8 26.0 23.3 19.1 27.4 46.0 29.8 27.7 28.6 24.0 40.1 30.7 43.6 33.8 20.9 53.3 22.1 25.5 42.6 31.6 26.5 30.7 24.4 26.3 25.4 36.6 28.5 37.4 29.5 35.2 23.9 21.9 35.4 32.9 25.9 11.8 39.5 34.3 26.7 8.1 3.3 14.7 5.6 6.8 7.1 1.4 30.8 15.7 23.0 44.6 14.8 36.0 16.0 21.7 22.0 10.1 17.5 11.5 19.8 20.7 15.9 25.9 17.5 22.3 21.5 27.4 21.6 30.2 14.7 20.6 21.9 9.0 16.0 15.2 11.7 34.7 30.8 17.4 41.5 29.1 18.8 18.9 14.5 38.4 17.2 15.7 16.0 15.9 12.7 6.7 16.0 22.3 25.4 15.1 17.0 28.0 10.0 17.7 19.5 10.5 27.1 22.0 27.8 16.6 28.4 15.7 15.2 22.7 24.8 19.2 30.5 16.5 19.7 26.2 8.5 10.5 2.1 6.8 7.1 2.0 5.6 6.4 4.9 6.1 1.3 8.1 6.8 5.7 14.7 6.8 5.6 3.3 4.5 1.4 51.9 54.4 58.9 51.4 46.0 29.8 30.7 43.6 42.6 35.4 107.2 86.7 52.8 42.9 64.5 144.1 0.0 63.7 61.6 70.5 0.0 265.1 31.5 0.0 0.0 86.9 51.4 61.9 23.3 0.0 23.6 49.2 69.4 73.0 70.0 33.8 74.7 86.1 95.8 62.6 94.2 73.4 62.1 62.4 0.0 53.3 63.6 0.0 48.9 59.4 0.0 132.6 25.8 55.6 20.2 36.6 81.8 42.6 117.6 48.7 51.0 MGLL "HU-K5, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-127823250 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "monocytes: 404.8;Pancreatic endocrine cells: 322.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 11.6;intermediate monocyte: 28.5;non-classical monocyte: 18.3;plasmacytoid DC: 30.4" "Group enriched" "Detected in many" 13 "dendritic cells: 30.4;granulocytes: 11.6;monocytes: 28.5" "Cell line enhanced" "Detected in many" "BJ: 46.5;BJ hTERT+: 53.6;LHCN-M2: 42.8;RPTEC TERT1: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 4300000 Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 72.2 6.7 29.4 22.6 29.7 7.5 39.0 32.8 36.9 13.3 36.3 8.3 8.4 16.5 8.7 10.8 63.8 16.3 24.1 35.5 23.6 10.2 22.6 32.1 32.4 6.0 15.4 17.8 3.9 3.6 1.7 5.0 18.9 10.2 10.6 27.6 10.0 31.4 13.6 40.9 11.9 22.3 13.6 12.2 19.2 17.5 3.2 15.5 2.4 6.4 33.4 19.7 14.4 14.5 1.8 30.4 11.6 28.5 0.6 0.9 6.0 11.2 10.1 0.0 0.0 17.8 21.0 1.3 46.5 53.6 10.3 16.6 0.3 4.6 2.9 12.9 15.7 3.1 0.4 0.0 6.1 5.7 5.0 0.1 0.3 7.2 0.0 6.4 0.0 0.3 7.8 3.6 19.3 21.1 5.8 21.8 0.1 0.0 0.5 42.8 1.1 0.0 0.1 0.0 7.3 16.0 0.0 5.5 23.8 38.6 1.2 6.0 0.4 8.0 15.8 2.7 0.4 0.7 0.4 27.9 11.3 3.3 27.2 6.3 0.0 0.0 9.5 23.4 0.6 35.0 4.2 2.8 11.6 0.2 28.5 0.9 1.8 0.2 0.3 3.1 0.2 0.0 0.0 0.5 0.6 18.3 30.4 0.0 6.0 29.4 29.7 32.8 36.9 23.6 10.2 15.4 17.8 10.2 15.5 181.7 90.0 5.2 8.0 20.3 16.7 42.0 119.8 56.2 34.2 40.1 0.0 68.4 142.6 90.3 3.6 101.2 167.0 23.3 144.8 129.8 47.2 9.2 8.1 126.2 122.7 0.0 85.0 14.7 24.4 4.0 30.2 33.6 20.3 404.8 177.1 46.3 322.3 129.8 65.4 60.0 6.1 84.1 176.1 0.2 1.1 19.4 60.8 10.2 49.8 4.2 MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996086-151008375 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 15 "Distal tubular cells: 33.2;Ductal cells: 11.3;Proximal tubular cells: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 26.3;eosinophil: 19.1;neutrophil: 30.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 30.4" "Cell line enhanced" "Detected in many" "T-47d: 27.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028351, HPA028358, HPA061086" Approved Enhanced Nucleoplasm NA NA 240000 Nucleoplasm "HPA028351: AB_10611110, HPA028358: AB_10601102, HPA061086: AB_2684425" "unprognostic (5.73e-2)" "unprognostic (2.86e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-1)" "unprognostic (3.39e-2)" "unprognostic (6.90e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.22e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.43e-8)" "unprognostic (2.30e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (6.06e-2)" 9.2 9.7 14.0 6.7 31.1 5.6 13.0 18.4 21.2 13.1 13.5 53.8 14.8 14.0 14.7 6.5 24.1 14.4 11.8 24.5 17.6 10.1 26.6 12.2 10.9 5.2 37.5 13.5 19.3 37.3 26.2 12.3 5.9 25.0 11.7 14.8 16.9 25.3 21.0 11.9 17.1 12.1 13.7 34.1 10.7 15.9 14.7 35.7 0.9 39.9 7.9 10.3 12.3 13.0 0.6 4.0 30.4 3.2 1.5 2.2 3.4 6.1 4.0 4.3 6.1 7.8 6.5 3.6 2.0 5.1 2.8 4.5 8.6 14.7 0.4 4.8 2.6 0.9 3.1 3.4 3.7 1.3 4.6 5.1 6.0 7.4 7.3 1.7 1.8 2.4 5.3 3.4 5.1 1.4 9.6 7.2 2.1 3.7 15.5 2.9 9.5 0.3 4.0 2.0 1.9 1.4 4.5 0.8 18.9 13.4 12.2 7.5 5.5 3.8 7.0 4.2 2.1 27.9 6.1 6.7 2.4 3.2 1.2 1.7 5.7 5.2 20.6 5.8 4.0 11.4 26.3 3.2 19.1 0.1 1.5 0.1 0.3 1.3 0.3 4.0 0.6 2.2 0.7 30.4 1.5 0.9 0.6 1.6 3.4 14.0 31.1 18.4 21.2 17.6 10.1 37.5 13.5 25.0 35.7 8.9 4.3 0.0 0.0 0.0 0.0 0.0 0.0 4.0 6.8 3.5 0.0 3.4 33.2 11.3 0.0 0.0 0.0 0.0 6.1 0.6 0.0 0.0 3.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 7.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 MINDY2 "FAM63B, KIAA1164" ENSG00000128923 "MINDY lysine 48 deubiquitinase 2" Q8NBR6 15 58771192-58861900 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Alveolar cells type 1: 137.0;Collecting duct cells: 78.5;Extravillous trophoblasts: 84.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 40.6" "Low region specificity" "Detected in all" "HPA051103, HPA063669" Approved Enhanced Nucleoplasm No No Nucleoplasm "HPA051103: AB_2681345, HPA063669: AB_2685082" "unprognostic (4.71e-2)" "unprognostic (8.92e-3)" "unprognostic (4.63e-2)" "unprognostic (4.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (8.60e-2)" "unprognostic (7.23e-2)" "unprognostic (7.09e-2)" "unprognostic (2.36e-3)" "unprognostic (4.74e-2)" "prognostic favorable (3.00e-8)" "unprognostic (2.53e-1)" "unprognostic (3.59e-1)" "unprognostic (6.76e-2)" "unprognostic (4.77e-2)" 14.0 9.2 15.5 8.8 14.7 5.6 11.1 41.0 15.4 12.4 8.8 12.4 11.8 5.8 13.0 8.0 11.8 11.7 10.4 16.7 14.6 12.6 16.9 5.8 12.5 6.1 16.2 15.5 11.7 6.4 15.5 12.5 21.9 14.9 15.0 6.6 11.7 7.7 11.8 6.1 11.4 6.5 13.6 16.9 9.4 7.8 6.2 15.8 8.6 15.8 5.4 6.0 13.1 9.1 4.6 2.9 5.5 3.1 1.9 5.5 1.4 5.8 2.9 4.1 2.5 6.2 11.4 6.5 5.4 11.5 1.7 2.4 4.6 2.9 3.0 5.9 6.5 3.0 5.7 7.5 4.3 2.6 3.0 2.7 4.2 3.2 4.1 3.8 3.1 3.9 5.0 7.3 2.0 4.5 6.4 4.1 3.2 7.2 3.4 3.9 0.7 3.9 2.4 8.7 0.8 1.5 1.7 11.8 3.2 5.0 6.6 3.7 2.8 3.9 5.5 9.8 9.1 1.7 6.7 4.8 2.4 2.1 40.6 2.3 3.0 4.3 3.0 5.3 5.2 5.7 5.5 1.8 3.3 3.2 1.6 5.5 2.7 2.8 3.5 0.6 4.6 2.4 3.3 3.9 1.9 3.1 2.9 2.2 1.4 15.5 14.7 41.0 15.4 14.6 12.6 16.2 15.5 14.9 15.8 137.0 33.7 0.0 0.0 0.0 0.0 0.0 0.0 52.2 33.0 78.5 0.0 54.4 39.7 36.7 0.0 0.0 0.0 0.0 18.8 84.1 0.0 0.0 10.5 0.0 28.7 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 16.2 0.0 0.0 23.8 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 44.5 0.0 0.0 0.0 MINDY3 "C10orf97, CARP, DERP5, FAM188A, FLJ13397, my042" ENSG00000148481 "MINDY lysine 48 deubiquitinase 3" Q9H8M7 10 15778170-15860520 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 1: 20.8;Ciliated cells: 21.4;Hofbauer cells: 31.6;Syncytiotrophoblasts: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038400, HPA038406" Uncertain Supported "Nucleoplasm,Nuclear membrane" NA NA "Nucleoplasm, Nuclear membrane" "HPA038400: AB_10669724, HPA038406: AB_2676001" "unprognostic (9.20e-2)" "unprognostic (5.84e-2)" "unprognostic (3.09e-1)" "unprognostic (3.26e-1)" "unprognostic (1.99e-2)" "unprognostic (3.67e-1)" "unprognostic (8.29e-2)" "unprognostic (2.81e-2)" "unprognostic (3.85e-2)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (6.50e-2)" "unprognostic (1.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.19e-1)" 14.6 22.0 17.9 10.0 22.2 15.2 18.4 22.0 32.0 19.1 13.7 19.7 11.4 8.2 18.6 20.0 13.4 15.3 13.3 8.9 20.1 18.8 16.0 15.8 15.5 11.9 22.9 14.0 18.1 12.8 16.3 14.4 20.1 25.8 18.9 18.0 13.5 11.8 16.5 4.1 15.3 11.4 16.7 32.0 11.8 14.6 18.8 16.1 10.5 17.2 7.7 12.6 17.8 14.1 3.4 4.2 5.7 8.0 3.4 6.2 2.9 6.6 6.2 12.1 12.8 18.0 17.1 10.0 21.3 10.8 16.3 19.1 5.4 10.5 5.0 4.1 23.0 11.3 6.2 10.3 12.7 14.6 15.3 14.4 16.3 8.8 5.8 22.6 3.3 13.7 12.9 11.1 14.5 10.3 16.0 12.8 12.2 9.9 4.2 16.1 7.2 7.1 4.0 4.4 10.8 11.9 3.5 7.1 3.5 18.2 5.1 10.0 11.1 10.4 10.1 8.5 11.3 11.3 8.1 13.4 10.6 8.2 17.8 6.2 23.1 9.8 8.6 12.2 7.4 8.4 5.7 3.6 3.1 4.9 7.1 4.1 3.1 3.4 5.2 4.0 3.4 2.3 4.4 3.1 3.4 8.0 4.2 6.2 2.9 17.9 22.2 22.0 32.0 20.1 18.8 22.9 14.0 25.8 16.1 20.8 11.8 0.0 0.0 0.0 0.0 0.0 0.0 21.4 6.8 14.0 0.0 16.7 16.6 10.4 0.0 0.0 0.0 0.0 7.3 13.3 0.0 0.0 1.1 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 7.1 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 8.9;Ciliated cells: 33.5;Collecting duct cells: 12.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.1;T-cells: 2.7" "Cell line enhanced" "Detected in many" "K-562: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol NA NA "Vesicles, Cytosol" "HPA019475: AB_1848806, HPA030129: AB_10599621, HPA030130: AB_10601565" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.07e-1)" "unprognostic (6.01e-3)" "unprognostic (3.81e-2)" "unprognostic (5.25e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (9.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" 9.3 6.7 9.3 2.6 15.2 4.1 7.0 3.4 15.1 10.8 6.6 5.4 16.6 2.9 15.6 16.2 5.7 20.7 10.0 7.5 8.4 5.1 9.4 3.8 14.2 2.4 4.3 9.5 14.8 5.6 9.6 16.1 6.2 9.0 9.4 4.3 7.8 5.3 15.9 3.7 5.1 3.7 10.8 3.6 2.3 5.8 20.1 5.0 1.5 12.5 3.6 2.2 6.4 6.3 0.0 1.1 0.0 0.3 0.0 2.7 0.7 2.1 5.3 2.8 8.5 2.5 9.6 4.1 3.1 5.4 2.4 2.0 0.0 4.0 0.0 3.6 2.0 3.3 2.3 1.9 1.7 2.3 0.0 3.1 1.7 2.8 0.0 3.1 2.3 1.2 4.9 2.8 7.0 1.4 0.2 3.4 1.6 16.4 1.0 2.0 0.0 1.3 0.7 8.0 7.4 1.2 0.4 0.0 0.5 6.4 1.0 5.2 7.1 2.1 11.3 1.2 3.4 5.7 1.7 2.0 0.1 1.3 2.4 1.3 2.3 3.0 0.0 4.5 0.1 10.0 0.0 0.1 0.0 0.6 0.0 2.7 0.0 0.8 0.2 1.1 0.0 0.3 0.5 0.0 0.0 0.3 0.0 0.5 0.7 9.3 15.2 3.4 15.1 8.4 5.1 4.3 9.5 9.0 5.0 8.9 3.8 0.0 0.0 0.0 0.0 0.0 0.0 33.5 3.4 12.2 0.0 2.1 3.3 2.3 0.0 0.0 0.0 0.0 1.2 3.5 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553460 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Intracellular and membrane" NA NA 320000000 "HPA026859: AB_1853961" "unprognostic (9.15e-2)" "unprognostic (8.76e-3)" "unprognostic (2.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.20e-3)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (4.55e-1)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (6.50e-3)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" 9.9 27.6 8.5 8.0 8.9 24.6 14.2 12.0 9.2 9.1 13.3 8.0 12.8 16.7 12.1 10.0 5.4 8.4 9.5 7.2 8.5 10.0 19.4 28.9 9.5 10.1 8.2 6.3 11.1 18.2 10.2 18.5 31.4 7.6 11.6 12.4 9.3 8.9 12.2 5.9 9.5 19.4 7.4 8.2 8.2 8.9 8.8 8.5 13.5 13.1 5.3 6.5 8.7 13.9 8.9 13.5 8.5 12.9 10.4 16.4 9.3 8.3 12.9 12.9 18.9 22.0 18.2 10.9 13.6 23.3 13.5 18.1 6.8 16.4 7.2 12.7 16.0 9.0 13.0 13.6 12.4 15.4 16.5 16.2 18.5 5.2 25.2 16.5 7.9 16.9 15.9 16.0 15.0 9.1 24.4 16.9 6.5 10.8 35.3 15.6 6.2 5.2 11.2 9.3 6.3 9.3 0.0 7.4 4.9 17.7 4.7 4.7 14.8 12.9 2.7 22.6 15.2 7.8 6.6 14.8 8.7 10.5 10.3 13.0 11.5 11.8 1.9 13.9 12.2 6.3 8.5 10.3 4.6 11.6 12.9 10.3 8.9 11.0 13.2 13.5 7.3 10.6 11.9 0.7 10.4 10.8 7.8 16.4 9.3 8.5 8.9 12.0 9.2 8.5 10.0 8.2 6.3 7.6 8.5 6.0 13.8 10.7 7.2 2.5 13.2 3.9 20.4 14.7 5.7 7.0 2.0 16.9 5.0 13.7 11.4 7.8 12.6 70.0 14.6 15.3 13.1 7.1 24.3 50.4 11.9 9.5 12.6 18.4 13.7 0.5 8.6 10.1 10.1 12.6 19.4 11.8 10.8 17.3 7.8 23.5 14.1 0.0 9.2 9.5 13.2 3.0 6.8 8.7 10.4 4.3 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889419 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 35.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 7.3 14.9 6.2 7.1 12.2 4.4 11.0 4.7 10.3 8.1 12.2 12.9 12.1 8.4 9.6 20.4 14.4 17.1 11.7 16.9 8.8 5.3 24.7 12.0 8.2 8.4 5.1 8.0 8.5 14.7 8.1 15.4 5.3 9.1 10.9 13.1 9.1 12.9 10.1 16.2 22.0 8.9 11.5 4.4 6.5 9.8 13.9 4.9 8.9 10.9 15.7 11.1 11.2 8.6 9.2 6.5 1.2 10.6 9.7 10.0 3.9 7.8 8.9 4.4 10.3 10.1 13.7 9.4 5.7 8.9 8.6 7.3 11.8 15.7 9.3 5.8 4.6 7.6 19.9 10.1 12.0 10.7 5.4 6.4 4.0 4.2 10.1 8.3 9.4 2.2 6.7 15.0 8.9 7.9 7.3 10.7 7.1 7.7 1.5 13.4 5.8 6.7 5.3 6.1 35.4 9.0 7.5 11.9 8.0 19.2 5.2 10.3 3.4 6.1 10.0 12.0 5.8 10.3 5.3 5.9 5.2 4.4 8.6 6.1 1.5 2.1 5.0 9.1 4.8 6.5 0.0 3.0 1.2 7.9 3.7 10.0 9.2 7.7 7.1 6.5 7.7 7.4 7.3 0.0 9.7 10.6 5.6 5.1 3.9 6.2 12.2 4.7 10.3 8.8 5.3 5.1 8.0 9.1 4.9 14.9 7.5 0.8 5.9 35.4 3.2 80.7 15.3 36.1 10.3 8.7 5.9 8.4 24.9 20.8 6.6 3.7 5.5 0.0 9.4 7.7 4.5 5.6 2.3 5.6 8.7 14.3 5.8 2.5 2.7 5.9 6.4 4.1 5.0 3.6 6.4 5.2 8.0 8.6 8.1 18.1 10.7 0.0 5.2 9.5 19.0 36.9 4.2 2.9 12.4 3.8 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183729 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 61.1;intestine: 136.0;kidney: 64.9" "Cell type enhanced" "Detected in many" 8 "Basal glandular cells: 62.4;Cytotrophoblasts: 71.6;Proximal tubular cells: 101.6;Syncytiotrophoblasts: 105.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 129 "neutrophil: 61.1" "Lineage enriched" "Detected in single" 129 "granulocytes: 61.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 97.1;BJ hTERT+: 146.1;HSkMC: 94.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 26.8" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 99000 "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 26.5 0.4 0.4 3.4 7.4 1.9 14.7 0.4 0.7 4.8 65.6 0.1 18.4 74.0 2.8 8.1 0.7 0.9 8.5 1.8 0.3 0.4 64.9 11.5 13.7 3.0 2.1 0.2 0.9 0.6 0.0 0.6 35.0 8.6 18.3 0.4 1.3 3.7 11.3 11.7 1.4 136.0 0.6 0.9 2.7 0.7 1.0 1.2 13.2 1.0 5.3 2.3 3.4 4.9 0.1 0.4 61.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 39.4 97.1 0.2 21.7 146.1 11.1 28.7 0.0 0.0 23.9 0.0 19.2 15.1 0.0 0.7 0.8 26.7 0.0 0.1 0.0 0.0 0.0 31.6 0.0 0.0 94.2 0.1 5.9 42.5 12.3 8.4 0.0 0.0 0.0 17.7 0.1 0.0 0.1 0.9 0.0 0.1 39.7 18.7 0.1 0.6 0.2 0.0 0.2 0.0 0.0 4.2 8.9 0.0 0.0 23.8 47.7 0.1 16.3 3.7 0.0 0.0 31.5 5.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 61.1 0.0 0.0 0.4 0.0 0.0 0.4 7.4 0.4 0.7 0.3 0.4 2.1 0.2 8.6 1.2 8.9 18.3 0.9 62.4 0.7 0.0 1.1 17.8 2.7 19.4 21.0 0.0 71.6 8.3 0.1 0.3 0.6 0.0 0.0 0.0 48.9 19.2 29.2 2.3 48.9 8.1 0.0 0.0 3.1 1.8 0.2 3.7 2.7 0.0 0.0 0.2 0.0 0.3 0.0 1.1 101.6 0.0 0.0 3.1 0.2 0.4 0.3 105.4 0.0 0.0 29.2 MMEL1 "MMEL2, NEPII, NL1, NL2, SEP" ENSG00000142606 "Membrane metalloendopeptidase like 1" Q495T6 1 2590639-2632990 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.2" "Cell type enhanced" "Detected in many" 14 "Cholangiocytes: 28.1;Early spermatids: 82.5;Late spermatids: 27.3;Paneth cells: 37.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 8.5" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 17.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007876, HPA008205, CAB020786" Uncertain "Intracellular and membrane" NA NA "CAB020786: , HPA007876: AB_1854012, HPA008205: AB_1854011" "unprognostic (5.80e-2)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (2.71e-2)" "unprognostic (1.45e-1)" "unprognostic (7.96e-2)" "unprognostic (1.36e-2)" "unprognostic (2.37e-1)" "unprognostic (4.54e-3)" "unprognostic (2.44e-2)" "unprognostic (4.79e-2)" "unprognostic (3.18e-1)" "unprognostic (2.82e-1)" "unprognostic (2.18e-3)" "unprognostic (7.01e-4)" 1.5 0.5 0.8 1.8 8.5 0.6 1.8 0.4 0.6 4.3 4.2 0.4 1.9 3.2 0.8 10.3 3.0 3.0 9.6 1.3 1.0 2.6 1.4 0.4 1.4 1.4 1.7 0.4 1.1 7.3 0.3 0.4 0.7 0.5 4.2 1.4 0.4 2.0 2.0 0.4 0.3 2.6 0.9 0.7 1.4 7.9 30.2 0.9 0.8 1.1 0.8 0.8 3.7 1.6 0.6 1.1 6.6 5.1 2.3 6.1 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.5 0.0 17.8 0.0 0.1 1.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 1.5 6.6 0.5 3.9 0.3 0.6 1.7 0.7 1.1 0.0 4.5 2.2 1.0 2.3 5.1 0.2 6.1 2.2 0.8 8.5 0.4 0.6 1.0 2.6 1.7 0.4 0.5 0.9 0.0 0.0 0.0 4.6 0.0 0.0 0.8 28.1 10.7 2.3 17.4 0.0 0.0 0.0 7.1 82.5 0.6 15.7 0.0 3.1 0.0 0.3 12.4 0.0 0.0 1.3 0.0 1.2 0.6 1.5 27.3 1.7 0.5 0.0 0.0 14.9 0.5 2.7 37.7 1.1 0.0 0.0 0.0 0.4 0.5 0.9 0.0 0.0 0.0 9.7 10.9 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789920-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 62.4;stomach 1: 27.2" "Cell type enriched" "Detected in some" 7 "Pancreatic endocrine cells: 1303.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 90.2;HBF TERT88: 89.3;HUVEC TERT2: 234.8;WM-115: 115.7" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 430000 Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.2 0.1 0.3 12.3 0.3 0.0 0.9 0.3 0.3 0.3 2.7 0.3 0.2 3.2 4.8 0.2 3.3 0.1 62.4 0.4 0.2 0.1 0.7 1.3 4.7 0.2 0.2 0.2 0.2 1.6 0.0 0.2 8.6 0.5 0.7 3.0 0.3 2.0 0.2 0.2 0.3 8.8 0.2 0.4 1.8 27.2 2.2 0.2 0.4 0.3 1.3 0.9 11.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.8 90.2 36.9 9.6 0.7 0.0 0.0 0.4 21.6 14.2 0.3 0.0 12.6 89.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 37.9 3.2 0.0 234.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.7 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 12.1 30.6 0.0 1.3 0.1 0.0 0.0 0.0 0.7 0.0 115.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.3 0.3 0.2 0.1 0.2 0.2 0.5 0.2 3.0 1.6 0.0 14.4 2.1 0.0 0.0 35.7 0.0 23.9 3.5 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 184.0 0.0 0.2 5.4 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 7.2 0.0 0.0 1303.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.0 25.0 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770503-102780628 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "endometrium 1: 89.4" "Cell type enhanced" "Detected in some" 14 "Basal glandular cells: 38.9;Club cells: 70.5;Collecting duct cells: 27.9;Pancreatic endocrine cells: 62.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 102.2" "Region enriched" "Detected in single" 9 "pons and medulla: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 12.6;HUVEC TERT2: 16.2;SCLC-21H: 5.2" "Not detected" "Not detected" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.1 0.0 2.6 0.2 0.1 0.1 0.0 0.3 1.7 0.5 0.0 0.0 0.4 89.4 0.1 0.2 0.1 0.5 0.1 0.0 0.1 0.1 3.6 11.0 0.1 0.0 0.0 0.5 0.3 0.1 0.9 19.8 2.8 3.2 0.2 0.0 2.9 0.1 0.1 0.1 0.7 0.1 0.0 0.2 3.3 0.5 0.0 1.2 0.1 0.0 1.9 0.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 12.6 0.7 0.1 0.1 0.3 0.0 0.0 3.7 1.9 0.2 2.9 0.0 1.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.6 0.0 16.2 0.0 0.7 0.0 0.0 0.0 0.0 0.3 3.0 0.5 1.7 0.0 0.0 0.0 0.0 0.7 5.2 0.0 2.5 0.0 0.0 0.9 0.0 0.0 2.0 3.9 1.3 0.4 0.5 0.0 0.0 0.0 0.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 38.9 0.7 0.0 0.0 0.0 5.3 70.5 27.9 0.0 0.0 0.0 9.8 5.0 0.0 0.0 0.0 12.9 0.0 0.2 5.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.2 0.0 2.8 0.0 0.0 62.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 7.4 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102875034 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 42.4;urinary bladder: 13.2" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 80.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BJ: 4.2;fHDF/TERT166: 14.6;hTEC/SVTERT24-B: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 2.7 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.3 6.9 0.0 0.0 3.3 0.0 5.9 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.6 18.9 0.0 0.0 0.1 0.0 0.0 0.0 9.7 0.0 0.3 8.4 0.0 0.9 0.0 0.0 0.0 3.8 4.6 0.0 42.4 1.3 0.1 0.0 5.5 0.0 1.5 9.9 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.4 0.2 0.0 0.1 0.0 0.0 0.0 14.6 0.1 0.5 0.0 0.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.0 17.0 80.4 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 1.4 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836557-22849027 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Extravillous trophoblasts: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 96.4;HHSteC: 91.2;HSkMC: 92.7;hTERT-RPE1: 91.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 570000 Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 60.9 10.5 2.4 16.6 4.7 0.2 64.2 2.2 3.2 56.3 35.0 8.2 12.7 12.0 53.1 24.1 47.0 21.9 39.6 17.5 3.4 1.8 16.8 9.0 29.8 16.9 5.8 2.9 39.3 11.2 34.4 4.7 73.5 16.4 39.1 11.3 27.1 24.4 16.7 20.4 37.0 22.9 28.5 20.7 22.5 18.2 26.3 4.6 5.4 22.3 14.6 16.7 52.5 53.9 0.1 0.7 0.0 0.7 0.0 0.0 0.1 7.8 0.1 2.4 0.1 96.4 61.3 44.3 24.7 49.8 7.5 13.4 2.3 29.4 0.1 13.8 26.0 2.3 20.0 0.0 25.7 9.6 0.1 0.1 3.6 0.1 0.5 91.2 0.0 0.1 92.7 15.5 31.2 26.8 91.6 45.3 0.1 0.0 0.2 17.6 0.1 0.0 8.8 1.4 1.7 4.3 0.3 8.5 0.0 6.8 13.5 0.0 0.0 16.1 0.0 53.5 10.8 0.1 7.9 40.0 60.9 5.2 17.7 28.1 0.1 0.1 0.1 37.1 0.0 35.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 4.7 2.2 3.2 3.4 1.8 5.8 2.9 16.4 4.6 11.9 4.8 3.7 19.4 30.2 0.0 3.6 53.5 2.7 3.4 7.0 0.0 83.6 10.0 61.2 0.4 13.5 16.8 0.0 24.9 216.8 65.7 13.9 3.5 2.9 79.3 0.0 7.5 41.1 18.3 0.7 66.7 26.5 35.4 34.3 32.5 17.1 102.2 28.5 51.6 13.0 0.8 38.8 34.8 0.9 0.7 29.9 102.6 1.0 17.1 28.7 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 11 "Extravillous trophoblasts: 217.4;Fibroblasts: 249.9;Leydig cells: 315.0;Peritubular cells: 393.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 292.5;ASC TERT1: 85.2;hTERT-RPE1: 329.2;U-87 MG: 93.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 160000000 Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 197.5 9.0 1.2 13.2 1.6 0.0 136.4 0.8 1.4 74.3 74.4 2.4 36.9 5.6 85.0 123.0 52.3 25.7 115.4 54.0 0.9 0.5 9.4 3.5 38.9 3.9 1.5 1.1 71.0 6.5 0.7 2.2 58.9 2.2 66.8 18.7 36.4 18.6 20.4 68.6 68.2 22.6 57.1 1.8 12.4 20.5 57.0 1.1 1.3 20.6 31.8 9.1 84.1 105.3 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.3 0.1 9.7 0.1 292.5 85.2 15.9 25.0 57.5 5.0 4.0 0.0 0.1 0.0 20.1 44.1 1.9 2.7 0.0 0.2 2.9 0.0 0.0 0.0 0.6 0.1 27.7 0.0 0.7 72.6 0.0 26.0 0.2 329.2 32.7 0.0 0.0 0.1 16.8 0.0 0.0 0.3 7.7 0.0 0.0 0.0 2.3 0.0 0.8 0.3 0.1 17.6 4.6 0.0 0.1 45.4 0.0 1.7 45.9 79.6 7.6 15.2 3.2 0.0 0.0 0.0 93.1 1.3 14.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 1.2 1.6 0.8 1.4 0.9 0.5 1.5 1.1 2.2 1.1 0.0 0.3 0.0 13.0 108.4 5.2 3.1 0.0 0.0 3.4 10.4 0.0 5.4 0.0 1.7 11.5 11.9 0.0 0.0 0.3 217.4 249.9 2.7 0.0 0.0 25.6 1.6 27.1 15.4 0.0 26.9 315.0 5.3 121.4 0.0 0.0 5.0 6.9 0.0 393.8 0.0 1.8 12.9 70.0 1.2 2.1 89.5 14.4 0.0 0.0 3.8 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843803 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 177.5;salivary gland: 73.4" "Cell type enhanced" "Detected in some" 10 "Basal glandular cells: 11.5;Basal keratinocytes: 7.4;Club cells: 11.4;Early spermatids: 14.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 101.3;BJ hTERT+: 275.6;fHDF/TERT166: 119.3" "Low region specificity" "Detected in many" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 170000 Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 19.1 0.0 0.2 14.4 0.3 0.0 6.9 0.2 0.5 0.2 1.5 0.3 0.2 1.8 28.3 177.5 0.2 0.0 1.4 0.2 0.2 0.0 0.3 0.5 0.4 0.2 0.2 0.2 0.3 0.2 0.0 0.2 0.2 0.2 1.2 1.7 0.2 73.4 1.5 7.3 12.6 0.7 5.9 0.2 0.2 2.8 1.4 0.2 0.2 0.6 1.5 0.9 7.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 101.3 275.6 1.8 0.5 0.0 0.0 0.0 0.0 119.3 6.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.8 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.5 0.2 0.0 0.2 0.2 0.2 0.2 3.0 0.0 0.0 11.5 7.4 0.0 0.2 5.1 0.0 11.4 0.0 0.0 0.1 0.0 0.7 14.6 0.0 0.0 0.0 1.2 2.2 1.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.0 1.0 0.0 0.9 3.0 0.2 0.0 0.1 5.2 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530753 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 93.0;kidney: 129.5;salivary gland: 79.3" "Cell type enriched" "Detected in many" 6 "Ductal cells: 5335.6" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Region enriched" "Detected in single" 5 "pons and medulla: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 23.2;CAPAN-2: 129.5;EFO-21: 30.7;RPTEC TERT1: 56.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 6.8 0.2 0.2 1.2 0.2 0.0 28.8 0.2 0.2 5.2 0.2 0.2 2.1 0.0 17.2 12.3 3.3 16.4 93.0 0.2 0.2 0.2 129.5 1.4 5.0 0.9 0.2 0.2 3.9 23.5 0.0 0.7 2.7 1.3 42.0 0.0 0.2 79.3 6.7 0.2 7.8 0.3 0.5 0.2 0.2 0.9 9.4 0.2 1.2 0.3 1.4 4.5 19.9 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 129.5 0.0 30.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 56.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 1.3 0.2 80.4 30.5 0.0 310.5 0.9 0.0 0.6 119.8 113.8 646.0 964.8 0.0 0.3 0.0 5335.6 3.9 0.3 0.0 0.0 184.1 0.2 0.4 323.2 2.3 0.0 103.8 0.0 0.0 0.0 0.0 6.5 10.9 7.3 0.0 113.6 0.0 0.0 723.2 0.0 0.0 6.0 0.0 0.0 0.4 0.0 0.1 2.0 0.7 0.0 0.0 640.3 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711795-102727050 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "bone marrow: 119.3" "Cell type enriched" "Detected in single" 32 "Hofbauer cells: 4.3" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" "Group enriched" "Detected in some" 32 "neutrophil: 1.4;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 32 "granulocytes: 1.4;monocytes: 4.9" "Cell line enriched" "Detected in some" 8 "WM-115: 40.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA022935" Enhanced "Secreted to extracellular matrix" NA NA 83000 "HPA021221: AB_1854043, HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 1.9 0.1 0.2 0.2 0.4 119.3 0.3 0.1 1.7 0.1 0.2 0.0 0.0 0.1 0.6 0.1 0.1 0.1 0.1 9.0 0.2 0.3 0.4 0.8 12.6 2.6 0.3 0.0 0.9 0.9 0.1 0.6 1.4 0.2 0.1 0.1 0.1 0.3 0.1 0.6 0.3 0.1 0.2 0.3 18.7 0.2 0.1 0.1 5.2 1.9 0.0 0.1 0.2 7.6 0.0 0.0 1.4 4.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.9 0.0 0.0 1.7 0.2 0.4 0.1 1.7 0.2 0.3 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 64.0;blood: 63.2;bone marrow: 89.4;lymphoid tissue: 80.1" "Cell type enhanced" "Detected in many" 25 "Hofbauer cells: 273.8;Macrophages: 115.1;Melanocytes: 54.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 141 "neutrophil: 63.2" "Lineage enriched" "Detected in single" 339 "granulocytes: 63.2" "Cell line enriched" "Detected in some" 12 "NB-4: 89.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 57000000 Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 64.0 0.5 0.6 38.6 0.7 89.4 4.3 0.4 0.6 0.8 1.2 0.1 0.0 2.8 0.6 0.2 0.9 1.5 0.6 4.0 0.5 0.6 1.4 2.0 13.3 80.1 0.6 0.0 2.7 1.4 0.0 0.8 2.6 0.5 0.6 0.8 0.5 12.5 0.0 1.3 1.3 4.2 0.3 0.5 53.7 2.5 2.7 0.0 23.6 1.3 2.3 44.5 4.5 2.9 0.0 0.0 63.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 7.5 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 89.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.0 0.0 0.3 0.0 2.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.4 0.6 0.5 0.6 0.6 0.0 0.5 0.0 0.0 8.5 0.0 0.0 30.5 1.6 0.4 0.0 0.0 0.0 0.0 7.9 0.9 0.0 0.8 0.6 0.5 0.0 0.0 1.5 2.0 1.7 0.1 1.1 0.0 273.8 3.2 0.0 0.0 1.9 0.0 0.0 115.1 54.0 3.6 0.0 0.5 1.6 0.0 0.0 0.3 4.3 0.0 12.3 5.4 5.5 24.6 1.6 0.0 0.0 0.0 MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 10 "Late spermatids: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" NA NA 88000000 "Endoplasmic reticulum" "HPA011322: AB_2668483, HPA011969: AB_1849579" "unprognostic (5.66e-2)" "unprognostic (1.98e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (2.34e-6)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (3.32e-2)" "unprognostic (6.21e-2)" "unprognostic (4.36e-1)" "prognostic unfavorable (2.79e-8)" "unprognostic (1.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" 15.8 12.8 8.7 15.2 10.6 8.5 13.1 11.3 12.1 13.9 19.4 10.8 24.9 36.5 14.2 15.8 15.5 13.4 16.4 11.2 7.7 6.1 14.8 40.5 17.2 15.6 9.2 7.9 14.2 30.6 20.4 15.7 35.8 8.3 15.9 11.2 11.7 24.5 25.3 14.1 17.4 35.8 9.8 7.1 22.4 22.3 11.9 8.1 17.6 18.9 11.4 19.5 14.1 12.9 3.9 3.4 2.3 4.4 12.7 5.1 2.5 22.2 19.8 13.1 12.6 27.1 19.2 40.3 18.2 26.5 27.7 26.7 36.2 23.8 24.1 16.3 18.4 20.8 22.4 19.8 20.6 17.2 20.8 19.2 11.3 12.8 27.7 22.4 26.4 22.7 11.2 33.0 19.6 19.2 30.9 31.0 14.3 19.6 23.4 12.2 27.7 14.3 20.3 17.3 28.2 11.0 16.4 29.3 31.2 15.1 13.8 10.8 14.2 8.7 36.3 23.7 13.0 17.5 14.2 22.1 12.8 22.3 18.5 24.1 36.2 14.9 10.7 20.1 21.6 17.3 2.3 4.0 1.1 5.0 2.5 5.1 2.5 4.2 4.5 3.4 3.9 3.7 2.4 0.7 12.7 4.4 3.2 3.8 2.5 8.7 10.6 11.3 12.1 7.7 6.1 9.2 7.9 8.3 8.1 6.0 15.7 9.0 17.4 14.1 14.2 5.8 15.3 9.4 12.5 22.7 17.7 32.9 5.0 19.7 52.1 10.9 21.0 23.3 22.8 34.8 8.7 19.5 4.6 22.1 17.5 6.4 13.4 17.8 7.9 186.6 14.1 16.0 10.1 27.1 24.4 8.3 19.0 20.3 6.7 8.4 12.7 12.9 7.6 8.6 3.2 15.2 43.5 14.0 17.9 17.3 MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700746 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031627 Approved Cytosol NA NA Cytosol "HPA031627: AB_2673966" "unprognostic (1.44e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "unprognostic (6.82e-3)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.44e-4)" "unprognostic (9.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.48e-11)" "unprognostic (4.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-3)" 12.5 17.0 6.2 12.6 6.9 3.5 15.0 1.9 6.3 11.4 23.1 9.3 12.3 18.8 16.4 12.6 15.8 12.2 15.3 5.8 8.6 5.1 13.3 19.4 9.7 7.7 5.9 5.1 14.5 12.9 13.1 14.1 20.2 8.2 14.0 9.3 13.8 13.5 16.5 3.1 23.2 33.8 9.4 6.3 12.9 10.4 17.7 6.0 14.5 12.1 6.9 10.9 11.0 12.5 1.9 5.6 0.9 9.5 9.9 10.8 5.9 12.0 7.4 4.4 17.0 3.6 10.4 16.8 8.3 19.7 24.4 35.0 13.7 13.3 0.0 5.7 11.4 9.1 12.8 16.8 19.9 8.5 13.2 10.2 8.3 10.8 15.4 15.5 3.4 8.3 17.5 6.1 14.8 4.7 16.1 20.7 17.2 11.0 4.2 7.5 22.3 13.1 2.7 9.9 5.0 7.6 23.7 11.2 0.5 11.3 13.2 1.9 6.4 17.1 11.6 13.4 9.1 9.0 8.0 12.3 7.6 13.7 5.3 7.3 4.8 1.3 0.0 15.1 7.2 21.7 0.7 2.8 0.5 10.7 8.4 10.8 1.9 9.7 9.7 5.6 1.4 9.4 7.1 0.9 9.9 9.5 0.9 8.2 5.9 6.2 6.9 1.9 6.3 8.6 5.1 5.9 5.1 8.2 6.0 8.9 10.9 5.4 9.8 7.8 2.1 2.5 7.6 6.7 10.3 15.7 0.0 42.2 3.3 13.7 4.2 14.7 31.4 0.0 13.3 16.6 5.1 9.2 1.1 14.0 13.8 4.8 14.5 17.8 9.4 4.9 8.6 7.1 3.3 18.0 15.3 20.4 13.7 28.1 7.1 11.2 0.8 12.9 6.2 2.6 2.6 6.0 31.9 5.7 11.5 9.5 MOV10L1 "CHAMP, DJ402G11.8, DKFZp434B0717" ENSG00000073146 "Mov10 RISC complex RNA helicase like 1" Q9BXT6 22 50089879-50161690 "Enzymes, Predicted intracellular proteins" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.7" "Cell type enhanced" "Detected in some" 24 "Early spermatids: 110.5;Late spermatids: 224.1;Spermatocytes: 68.2;Spermatogonia: 38.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.3;HUVEC TERT2: 16.1;TIME: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019034 Approved NA NA "HPA019034: AB_1854070" "unprognostic (1.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.88e-2)" "unprognostic (7.91e-2)" "unprognostic (4.29e-2)" "unprognostic (4.05e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (9.43e-2)" "unprognostic (7.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.03e-1)" "unprognostic (8.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" 0.4 0.1 0.7 0.2 1.5 0.3 0.2 1.3 1.3 0.9 0.8 0.6 0.2 0.1 3.0 2.0 0.4 1.0 1.2 0.3 0.9 0.6 0.3 1.0 0.3 0.2 0.5 1.5 1.8 0.2 0.1 0.4 0.6 2.1 1.0 0.2 0.6 0.2 0.2 0.2 0.3 0.4 1.9 0.7 0.2 0.1 27.7 0.2 0.2 0.5 0.2 0.3 0.4 2.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.4 0.5 1.0 0.0 0.0 0.0 1.4 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 3.3 0.0 1.5 0.2 0.0 0.0 0.0 0.2 16.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 7.4 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.5 1.3 1.3 0.9 0.6 0.5 1.5 2.1 0.2 0.0 0.0 0.0 0.1 0.2 2.4 1.4 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 110.5 1.0 0.0 0.0 0.3 0.1 0.5 0.1 0.0 0.0 1.4 4.8 0.0 0.0 0.0 224.1 1.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.8 0.8 3.8 12.9 0.0 68.2 38.5 0.0 0.1 0.0 0.0 0.0 MPG MDG ENSG00000103152 "N-methylpurine DNA glycosylase" P29372 16 77007-85853 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006531 Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA006531: AB_1854075" "unprognostic (1.78e-2)" "unprognostic (8.48e-2)" "unprognostic (9.99e-2)" "prognostic favorable (2.82e-5)" "unprognostic (8.54e-2)" "unprognostic (3.27e-1)" "unprognostic (2.75e-2)" "unprognostic (1.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-2)" "unprognostic (1.83e-2)" "unprognostic (1.39e-2)" "unprognostic (1.86e-3)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (3.26e-1)" 20.8 32.1 18.4 21.1 18.4 25.3 33.2 18.3 32.1 19.5 20.4 12.6 24.6 21.0 22.6 30.5 21.5 18.5 28.5 37.4 16.7 15.1 16.1 32.0 20.1 39.7 15.8 18.2 23.8 36.5 8.0 21.7 19.0 16.5 23.2 7.2 15.2 47.1 24.2 33.6 19.0 19.4 19.2 13.6 25.6 27.3 10.9 11.2 18.3 29.2 22.4 22.8 27.2 25.2 33.5 38.8 27.2 27.4 41.2 31.1 22.4 14.0 20.5 5.6 17.1 10.3 23.5 14.0 20.1 27.8 13.1 14.4 12.9 18.9 10.0 17.6 11.4 6.5 18.0 3.9 8.8 2.0 17.1 14.9 6.5 10.4 19.2 29.8 6.7 40.2 22.6 12.2 14.7 6.1 17.5 22.8 11.3 14.2 18.0 17.0 48.4 11.7 31.1 10.1 8.1 22.4 22.3 6.7 38.0 10.9 5.1 4.6 11.7 10.6 11.5 25.3 2.7 16.4 34.9 19.9 10.7 13.6 14.5 9.9 17.6 5.9 12.7 19.8 19.5 38.1 14.2 27.4 27.2 22.7 19.2 20.6 33.5 21.8 22.6 28.5 30.6 16.8 17.2 14.0 41.2 15.7 38.8 31.1 22.4 18.4 18.4 18.3 32.1 16.7 15.1 15.8 18.2 16.5 11.2 3.0 24.6 65.6 62.0 31.8 13.4 1.1 30.6 20.1 22.7 38.4 3.9 68.9 28.2 68.7 6.3 43.1 60.4 0.0 99.2 74.2 79.8 90.4 54.4 44.9 80.7 9.5 47.8 47.3 65.5 3.6 60.9 47.4 54.0 72.1 66.3 38.4 109.6 66.2 54.5 52.3 9.1 84.1 64.9 18.8 43.7 35.9 51.7 62.9 63.6 97.9 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 56.1;Distal tubular cells: 48.0;Exocrine glandular cells: 52.2;Proximal tubular cells: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003634 Approved Approved Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA003634: AB_1851388" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 12.4 23.4 13.9 18.4 14.8 13.7 17.6 18.1 15.7 10.6 15.2 9.8 17.5 13.1 12.5 15.1 19.4 12.5 16.3 31.2 12.2 12.0 25.7 41.7 10.2 15.2 14.3 14.0 10.5 24.2 13.5 9.1 13.9 14.0 13.6 16.3 10.1 17.7 22.5 57.3 16.5 13.4 14.8 12.9 14.6 15.1 7.6 14.0 13.2 14.8 31.2 15.7 14.3 11.6 18.3 28.9 11.2 22.0 20.0 33.5 20.9 26.1 36.9 12.3 14.1 13.3 13.2 17.2 15.5 16.9 32.4 27.6 28.3 16.5 18.2 12.8 15.4 20.0 18.7 25.2 26.7 34.3 9.3 29.9 14.3 17.5 23.5 25.1 29.8 9.8 14.2 12.8 21.5 34.5 11.0 24.6 18.9 23.0 13.3 18.3 32.7 25.7 20.5 9.3 40.8 50.0 13.3 21.9 26.5 23.8 19.4 11.5 22.0 13.4 24.5 30.1 16.5 32.8 24.6 10.4 17.5 19.2 18.4 29.2 13.9 11.0 20.1 20.0 33.4 14.4 11.2 22.0 10.5 17.3 20.7 14.9 18.3 21.1 17.2 28.9 14.8 15.7 17.6 2.0 20.0 17.4 19.4 33.5 20.9 13.9 14.8 18.1 15.7 12.2 12.0 14.3 14.0 14.0 14.0 29.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 38.8 14.8 24.4 0.0 56.1 48.0 41.8 0.0 0.0 0.0 0.0 52.2 30.7 0.0 0.0 1.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 26.2 0.0 0.0 44.8 0.0 0.0 104.5 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.0 0.0 0.0 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" P11586 14 64388031-64463457 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Ligase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 121.6" "Cell type enhanced" "Detected in many" 8 "Hepatocytes: 125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes 250000 Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 18.9 9.0 8.1 8.4 18.1 9.7 12.2 5.7 15.9 7.1 9.3 9.0 4.0 7.5 8.5 6.9 12.0 6.7 6.4 10.6 8.4 6.5 20.5 121.6 6.8 9.2 8.0 10.4 10.1 13.4 13.1 5.6 5.6 10.0 5.5 11.4 9.3 11.6 5.6 26.5 7.6 7.3 8.8 6.9 8.3 7.9 2.3 7.4 15.6 8.6 14.0 12.5 8.7 7.3 21.1 12.8 0.5 13.2 12.8 14.9 8.4 72.5 41.3 15.7 34.2 16.9 13.8 25.5 28.5 19.6 37.0 36.7 40.1 33.4 30.5 13.5 16.9 18.6 35.7 48.4 28.3 43.3 30.3 31.9 37.8 41.4 30.4 12.5 29.0 20.6 10.7 9.2 33.0 17.9 15.3 23.0 30.9 28.1 25.1 28.0 60.2 46.7 17.0 28.7 46.2 43.8 37.3 54.6 27.6 27.8 42.5 34.0 13.2 47.6 25.9 14.3 15.3 40.3 14.7 14.1 27.9 48.4 25.7 34.1 16.8 20.6 53.8 25.6 33.5 31.6 0.2 8.2 0.1 8.1 13.2 10.9 21.1 9.0 9.9 12.8 11.6 7.6 10.1 0.5 12.8 10.3 3.2 14.9 8.4 8.1 18.1 5.7 15.9 8.4 6.5 8.0 10.4 10.0 7.4 17.9 26.3 11.5 9.9 12.2 0.0 38.1 17.8 12.0 20.5 15.7 0.0 20.0 34.9 15.4 0.9 9.9 5.2 0.0 9.0 24.2 10.6 8.3 49.7 125.3 21.6 0.0 2.9 7.4 11.3 0.9 12.0 10.9 13.5 14.4 11.9 0.0 10.8 2.9 12.4 49.9 0.0 19.4 18.6 0.9 7.5 9.4 8.2 20.0 21.3 9.9 MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74198562-74217565 "Enzymes, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "monocytes: 263.3;Smooth muscle cells: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved Supported Mitochondria "Intracellular and membrane" NA NA Mitochondria "CAB003684: AB_425867, HPA049657: AB_2680842" "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.07e-5)" "prognostic favorable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" 26.2 5.7 5.8 21.6 14.1 12.1 21.9 3.0 8.0 15.1 12.4 5.9 12.6 10.1 15.8 8.7 14.1 17.5 10.5 12.1 10.0 8.2 12.0 3.4 15.9 21.0 19.0 1.5 20.6 39.7 1.5 15.6 8.2 16.1 12.7 15.3 3.0 32.9 12.0 39.4 8.6 9.2 21.0 25.6 26.3 15.3 11.9 11.8 8.4 11.4 16.7 23.5 20.3 41.8 4.8 11.4 13.6 19.7 10.7 12.7 6.3 18.6 6.9 7.8 26.6 8.6 9.7 20.6 23.5 15.9 13.8 19.6 15.9 7.9 39.4 6.3 12.7 15.4 6.6 25.9 13.8 26.1 21.2 10.8 38.0 3.9 15.4 35.2 27.6 25.4 20.0 44.1 17.2 74.8 7.1 9.2 63.6 17.5 57.4 13.5 11.7 17.3 34.2 17.0 27.2 11.5 19.3 21.9 34.7 7.9 5.5 20.4 14.9 8.1 24.4 55.1 5.9 20.9 38.4 4.0 4.3 34.7 9.8 26.3 47.5 21.0 32.0 11.9 33.9 12.2 13.6 8.1 9.6 3.3 19.7 4.8 4.8 6.0 3.6 11.4 3.0 4.3 3.3 1.1 10.7 19.1 5.0 12.7 6.3 5.8 14.1 3.0 8.0 10.0 8.2 19.0 1.5 16.1 11.8 14.9 26.5 62.1 28.1 79.3 0.0 8.2 7.6 2.7 13.6 1.8 0.0 20.5 3.3 54.8 3.2 18.0 6.9 93.5 92.6 49.1 52.6 48.5 53.0 0.6 64.6 0.0 18.3 13.5 55.9 2.9 21.0 92.7 67.4 263.3 33.2 0.0 75.9 5.8 19.8 1.4 0.0 135.8 264.7 30.1 55.8 65.2 11.7 30.5 21.6 55.0 MTHFD2L MGC72244 ENSG00000163738 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like" Q9H903 4 74114174-74303099 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Hepatocytes: 105.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035434 Uncertain NA NA "HPA035434: AB_10601038" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "unprognostic (2.03e-1)" "unprognostic (2.32e-2)" "unprognostic (1.52e-2)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (7.73e-3)" "unprognostic (1.42e-4)" "unprognostic (3.45e-3)" "unprognostic (4.23e-2)" "unprognostic (5.07e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (1.19e-1)" "unprognostic (3.00e-1)" "unprognostic (1.81e-3)" 5.4 11.7 10.2 6.0 8.8 5.2 10.3 6.9 8.5 4.5 5.6 5.9 8.2 5.3 5.6 10.9 6.3 5.0 5.6 17.7 9.3 10.7 6.9 16.2 7.0 5.8 10.5 4.1 5.8 13.6 6.1 7.4 5.8 6.6 5.3 4.0 4.8 4.9 6.2 9.3 4.2 5.6 4.9 11.0 5.1 4.1 2.9 7.3 14.8 10.5 5.0 3.8 3.8 8.4 3.9 3.9 1.4 6.5 2.5 2.7 2.5 2.6 2.8 3.9 3.6 1.4 2.1 0.9 3.3 2.6 2.2 2.4 2.1 2.5 2.9 4.5 1.5 1.6 1.7 3.2 2.1 3.3 2.9 1.9 3.5 1.9 2.5 2.5 5.5 0.7 1.5 5.1 3.3 7.9 4.1 4.6 6.5 6.2 3.6 2.7 2.6 10.2 7.9 1.2 4.3 3.1 10.4 2.7 4.8 14.2 1.3 3.7 8.1 1.8 2.8 3.3 4.5 1.5 3.9 4.7 2.5 3.8 4.8 5.4 3.6 4.6 8.5 15.6 1.3 3.8 0.4 2.1 0.9 0.7 2.0 0.7 3.9 0.6 0.9 3.3 1.5 2.1 2.2 1.4 2.5 6.5 3.9 2.7 2.5 10.2 8.8 6.9 7.3 9.3 10.7 10.5 4.1 6.6 7.3 20.8 15.8 16.8 49.0 14.7 0.0 21.3 25.5 22.7 21.6 47.1 0.0 16.4 71.3 20.8 53.1 14.3 16.8 46.7 16.6 6.3 12.2 87.5 10.3 105.4 21.6 0.0 35.7 18.4 22.7 16.4 11.8 19.6 15.1 11.8 31.5 0.0 16.0 17.5 8.1 35.8 0.0 25.8 18.4 6.5 10.0 19.7 10.3 12.2 33.8 58.9 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568619-150673322 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" NA NA "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favorable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 10.7 17.9 15.0 10.2 16.4 11.1 9.2 10.6 10.8 9.1 21.5 12.5 12.7 12.8 10.9 10.9 11.1 11.1 8.0 9.0 14.3 12.0 17.9 19.9 12.2 12.4 17.3 9.3 13.8 7.5 21.4 11.9 21.5 12.9 9.5 21.6 8.3 10.2 12.9 11.2 10.2 21.0 8.0 17.2 15.3 8.6 12.1 16.4 14.5 12.7 8.3 13.9 8.5 9.1 6.9 7.9 18.4 7.2 10.1 7.7 4.6 8.5 3.9 5.5 2.0 5.1 5.0 3.5 4.1 5.6 4.7 5.2 3.0 4.8 13.8 7.3 5.2 14.8 6.1 4.0 7.9 5.8 3.7 3.5 3.7 3.7 9.1 3.8 15.3 12.6 3.0 9.5 3.8 8.1 4.7 6.1 6.0 2.4 12.8 5.7 2.9 4.2 15.9 2.8 8.5 5.1 5.1 3.1 2.7 8.1 4.8 1.4 1.5 3.5 7.4 5.2 8.1 2.6 22.3 5.3 3.2 1.9 8.1 4.2 2.6 5.9 13.1 4.0 9.4 5.1 17.6 6.3 18.4 1.5 7.2 4.9 5.5 6.8 5.2 7.9 6.9 6.5 3.9 8.5 10.1 6.2 5.1 7.7 4.6 15.0 16.4 10.6 10.8 14.3 12.0 17.3 9.3 12.9 16.4 8.9 18.3 3.7 5.8 13.5 0.0 12.3 2.5 9.4 5.7 3.5 0.0 1.9 1.7 2.8 27.7 7.8 12.8 0.0 3.8 2.2 4.2 4.9 8.1 10.5 7.2 0.0 9.2 17.2 13.4 15.8 5.8 11.0 5.0 6.4 18.9 0.0 3.6 7.0 12.0 10.8 0.0 0.0 2.7 4.4 2.5 16.7 6.1 7.5 10.3 8.1 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765103 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002977, HPA018502" Approved Approved Centrosome NA NA Centrosome "HPA002977: AB_2666735, HPA018502: AB_1854185" "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.9 6.8 20.4 14.0 17.9 9.9 11.8 14.5 15.6 8.3 8.6 8.7 7.2 8.3 9.4 9.2 19.7 9.3 9.0 12.0 17.8 13.4 8.1 10.2 9.7 18.7 12.1 11.5 7.4 11.7 16.3 10.2 37.9 8.8 10.8 9.1 7.9 12.1 13.0 22.2 19.8 10.9 8.3 8.2 18.0 9.7 11.0 9.3 32.6 9.6 10.7 23.1 10.4 7.7 3.3 7.8 7.4 1.5 6.2 4.8 1.8 13.2 8.5 9.2 7.5 2.1 2.5 12.4 11.8 15.2 12.0 17.1 8.2 10.5 29.0 17.5 9.5 11.6 12.1 18.5 17.1 18.8 11.7 11.2 1.8 13.2 3.5 6.4 8.5 6.3 6.8 11.9 13.2 0.2 11.5 7.2 9.7 5.6 7.5 8.6 11.4 12.4 2.2 4.2 14.8 12.9 6.6 14.6 12.8 9.4 15.2 13.7 8.5 4.5 10.1 3.7 7.6 12.9 4.9 9.1 7.9 6.3 1.0 17.5 9.6 9.8 44.2 1.6 5.5 6.1 0.0 0.9 7.4 3.5 1.5 2.6 2.7 3.9 3.2 2.2 3.3 3.5 4.7 2.4 6.2 1.3 7.8 4.8 1.8 20.4 17.9 14.5 15.6 17.8 13.4 12.1 11.5 8.8 9.3 14.9 6.2 3.4 9.6 10.0 0.0 7.9 2.5 1.4 5.7 5.2 0.0 8.8 0.0 5.1 0.0 3.6 2.8 0.0 5.7 6.0 4.3 6.1 1.1 8.1 4.0 0.0 9.2 3.1 8.2 0.4 5.2 5.2 3.3 1.0 7.6 0.0 8.1 6.5 4.9 2.9 0.0 6.5 2.7 1.2 2.3 14.6 8.7 6.9 5.2 10.8 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95832882-95925315 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles NA NA Vesicles "HPA049831: AB_2680904" "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 16.4 10.4 14.2 12.1 19.9 5.3 15.4 14.9 23.3 14.1 13.5 22.6 4.9 8.0 14.1 7.5 15.5 13.3 15.4 13.8 18.1 13.9 16.9 4.5 14.3 13.6 27.5 13.6 14.5 11.0 15.9 8.2 25.1 21.3 17.6 14.5 19.6 18.8 12.3 6.8 9.7 9.5 18.2 30.0 10.5 13.6 29.0 21.8 12.2 11.3 7.7 11.7 13.4 14.3 5.4 6.6 9.7 4.9 11.8 14.2 6.6 9.4 10.1 23.3 16.9 8.2 12.7 19.5 17.7 15.8 17.6 15.9 23.9 19.2 6.8 21.2 18.6 14.9 13.1 19.0 19.3 15.9 12.4 9.2 14.1 25.3 13.4 18.8 23.9 11.7 10.6 12.9 23.1 23.2 18.0 26.5 15.3 17.4 6.5 16.5 7.0 11.9 11.1 18.9 22.8 14.3 10.0 13.6 6.4 18.1 50.8 14.9 17.4 17.5 14.8 7.9 15.3 11.7 10.2 27.1 20.6 18.9 15.0 16.3 6.1 16.8 6.2 8.6 6.6 20.8 9.7 3.3 1.4 11.4 3.9 12.3 5.4 7.7 14.2 6.6 4.8 4.1 11.0 0.9 11.8 4.9 3.4 6.9 6.6 14.2 19.9 14.9 23.3 18.1 13.9 27.5 13.6 21.3 21.8 3.0 7.5 5.1 13.3 9.2 0.0 14.0 0.0 9.4 12.5 8.7 0.0 8.0 8.3 15.9 48.9 19.5 7.3 0.0 14.6 26.0 14.0 13.2 18.5 0.9 11.0 0.0 15.5 10.4 9.1 87.8 10.3 7.5 3.3 9.0 9.1 0.0 14.2 2.9 11.3 20.7 0.0 32.3 20.0 34.6 16.4 5.3 7.6 7.9 8.4 13.2 MTMR3 "FYVE-DSP1, KIAA0371, ZFYVE10" ENSG00000100330 "Myotubularin related protein 3" Q13615 22 29883155-30030866 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034515, HPA034516, HPA061399" Uncertain Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA034515: AB_10669726, HPA034516: AB_10669727, HPA061399: " "unprognostic (4.39e-3)" "unprognostic (7.84e-2)" "unprognostic (2.46e-2)" "unprognostic (1.76e-2)" "unprognostic (5.61e-2)" "unprognostic (4.51e-3)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (3.42e-1)" "unprognostic (4.39e-1)" "unprognostic (8.33e-4)" "unprognostic (1.28e-1)" "unprognostic (5.35e-4)" "unprognostic (7.96e-2)" "unprognostic (7.64e-2)" "unprognostic (2.49e-1)" "unprognostic (8.38e-2)" 15.8 17.2 15.7 12.6 20.6 66.7 16.0 24.2 18.0 13.7 12.6 18.9 14.8 10.6 18.8 13.5 20.1 16.7 13.0 14.4 13.0 11.7 12.4 9.9 18.3 12.6 14.7 11.4 20.3 15.8 22.1 20.6 20.6 15.8 15.1 12.9 18.1 15.9 14.7 30.7 22.5 13.1 16.0 17.0 20.7 14.1 23.7 14.6 14.0 16.6 11.9 14.9 14.0 19.3 2.6 3.9 16.5 6.6 3.9 4.1 3.5 8.5 6.7 11.7 12.4 11.8 8.6 8.6 7.6 11.6 10.5 12.2 6.3 5.2 6.5 5.1 14.7 8.4 10.6 12.3 9.7 10.6 12.9 10.2 11.8 6.8 6.7 10.9 10.0 30.2 9.1 16.1 10.2 18.6 10.3 10.5 7.1 7.3 11.8 6.5 10.7 6.7 7.3 4.3 9.2 5.0 8.0 15.8 6.6 9.9 16.0 12.9 8.9 14.7 13.3 7.9 10.3 7.4 10.1 11.1 17.2 11.7 3.5 5.4 10.2 6.9 6.1 7.5 5.0 7.9 6.4 6.6 10.0 3.1 4.6 4.1 2.2 2.5 3.4 3.9 2.6 3.1 2.7 16.5 3.9 4.7 1.5 2.7 3.5 15.7 20.6 24.2 18.0 13.0 11.7 14.7 11.4 15.8 14.6 3.0 11.3 4.3 8.7 14.8 0.0 2.8 10.2 6.7 14.8 12.2 0.0 10.4 1.7 9.3 11.6 8.9 12.4 0.0 7.6 5.5 9.4 14.8 7.0 8.5 9.8 0.0 12.0 13.5 24.0 12.1 12.7 12.9 13.5 2.8 11.1 0.0 9.9 8.6 10.6 5.7 0.0 6.5 5.0 20.9 24.0 12.0 11.4 7.0 9.3 11.6 MTMR4 "KIAA0647, ZFYVE11" ENSG00000108389 "Myotubularin related protein 4" Q9NYA4 17 58489529-58517905 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hepatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (3.07e-1)" "unprognostic (6.52e-2)" "unprognostic (4.87e-3)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" "unprognostic (6.42e-2)" "unprognostic (4.97e-2)" "unprognostic (3.45e-3)" "unprognostic (6.82e-2)" "unprognostic (2.21e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (2.13e-1)" "unprognostic (1.59e-2)" "unprognostic (2.92e-2)" 8.7 9.9 16.6 10.3 18.7 14.4 11.6 32.7 22.7 8.3 11.4 18.3 6.7 17.7 10.3 16.2 9.5 10.1 6.7 8.3 15.8 14.4 14.6 32.0 8.0 13.4 16.5 15.4 13.3 10.4 16.2 11.2 29.8 36.9 10.9 14.8 11.1 8.7 9.1 6.1 11.8 17.3 9.4 10.9 13.3 9.4 15.2 17.3 15.5 13.9 3.4 18.2 9.7 8.2 8.4 6.3 9.9 7.9 3.3 5.8 3.8 9.5 10.5 16.0 15.5 9.9 10.1 12.4 5.8 10.0 15.4 14.3 10.2 6.3 20.1 8.3 6.0 12.2 5.7 17.2 10.0 16.6 20.7 11.9 13.7 8.4 13.5 11.1 14.2 12.5 10.4 8.1 10.5 16.9 10.1 11.1 13.6 11.7 14.6 7.6 14.4 28.0 9.5 3.9 18.3 10.7 18.0 12.0 9.9 7.2 20.3 25.5 24.6 5.7 6.8 7.9 8.6 13.2 9.9 5.9 24.1 15.5 6.8 7.0 12.1 13.3 15.1 38.7 10.8 7.2 4.7 5.4 9.9 4.3 6.8 3.9 8.3 5.2 4.7 6.3 8.4 5.6 5.8 6.6 3.3 7.9 3.7 4.9 3.8 16.6 18.7 32.7 22.7 15.8 14.4 16.5 15.4 36.9 17.3 8.9 6.1 17.6 11.6 6.8 0.0 8.1 15.3 0.0 10.3 3.5 0.0 10.3 0.0 8.0 4.3 8.8 40.4 0.0 5.7 15.3 8.3 13.3 5.8 54.3 11.8 0.0 16.6 12.3 13.2 4.5 13.3 9.9 11.8 36.1 15.8 0.0 7.8 20.7 16.3 9.0 0.0 0.0 8.2 4.6 5.3 7.2 41.6 14.6 14.6 7.3 MTREX "Dob1, fSAP118, KIAA0052, Mtr4, SKIV2L2" ENSG00000039123 "Mtr4 exosome RNA helicase" P42285 5 55307760-55425581 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 2: 39.4;Ciliated cells: 48.2;Club cells: 39.8;Exocrine glandular cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037379 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA037379: AB_10601713" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (1.32e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.79e-2)" "unprognostic (5.08e-1)" "unprognostic (4.17e-2)" "unprognostic (1.46e-2)" "unprognostic (5.05e-2)" "unprognostic (7.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.09e-1)" "unprognostic (3.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.11e-1)" 23.6 23.6 26.1 24.9 24.0 18.7 24.1 40.6 31.2 22.0 19.3 15.2 28.8 27.6 26.2 17.8 23.3 20.0 22.4 24.3 22.0 16.0 21.2 22.7 19.7 24.7 21.1 21.5 25.9 25.8 35.8 45.0 19.0 26.6 25.6 21.7 10.4 21.8 28.7 71.3 23.8 24.3 20.9 37.5 20.9 20.6 22.3 21.5 29.7 29.3 19.2 21.7 24.4 23.4 9.8 10.9 5.8 10.3 5.9 10.4 4.0 14.2 20.0 14.6 15.5 12.4 13.1 19.6 13.1 10.0 14.8 18.9 21.4 18.7 27.7 15.5 11.5 19.6 9.9 28.4 18.0 22.2 4.9 23.5 18.9 18.9 16.3 11.4 11.1 12.6 10.3 12.3 15.6 19.1 11.6 12.8 10.4 22.3 16.0 14.3 13.0 11.9 14.7 13.2 5.9 19.4 14.6 16.3 12.2 16.0 20.9 18.0 11.1 14.9 8.5 12.8 14.6 20.4 16.1 11.5 3.8 9.7 10.7 22.0 11.8 12.4 23.9 9.7 25.5 14.7 4.9 6.6 5.8 10.4 6.1 10.0 8.8 7.7 9.7 7.9 9.8 8.1 8.3 1.9 5.9 10.3 10.9 7.5 4.0 26.1 24.0 40.6 31.2 22.0 16.0 21.1 21.5 26.6 21.5 29.8 39.4 0.0 0.0 0.0 0.0 0.0 0.0 48.2 39.8 19.2 0.0 21.8 10.0 23.4 0.0 0.0 0.0 0.0 35.5 18.3 0.0 0.0 23.3 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 24.4 0.0 0.0 29.8 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 MUTYH MYH ENSG00000132781 "MutY DNA glycosylase" Q9UIF7 1 45329163-45340470 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cytotrophoblasts: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008732 Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA008732: AB_1854219" "unprognostic (6.30e-3)" "unprognostic (7.12e-2)" "unprognostic (6.29e-2)" "unprognostic (8.80e-2)" "unprognostic (3.43e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (4.76e-8)" "unprognostic (2.80e-2)" "unprognostic (7.12e-3)" "unprognostic (3.05e-2)" "unprognostic (7.80e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.25e-5)" "unprognostic (3.50e-3)" "unprognostic (1.62e-1)" "unprognostic (5.57e-2)" "unprognostic (5.49e-3)" 7.7 8.4 10.3 12.7 14.8 11.1 8.3 31.6 12.4 10.5 10.1 15.1 11.0 11.1 11.5 9.8 8.3 11.0 10.0 6.1 10.9 7.3 9.7 9.0 7.2 14.0 13.6 10.1 12.9 8.4 7.5 12.5 12.5 11.6 9.1 11.0 12.6 9.5 11.7 8.5 11.1 9.8 7.5 12.6 12.8 11.8 4.9 16.6 14.1 11.9 7.4 12.0 9.3 9.2 7.2 6.5 1.9 8.9 6.6 15.4 6.3 4.9 4.3 10.1 6.9 7.2 5.4 17.6 3.4 4.7 7.4 6.1 9.1 7.0 13.9 6.1 2.3 5.9 7.6 5.3 6.3 3.4 11.5 4.0 6.8 6.9 6.5 6.7 5.8 5.0 3.6 6.5 9.9 16.6 1.9 5.3 18.3 10.5 5.4 3.1 8.0 15.9 5.5 25.5 11.7 5.3 21.6 7.8 7.5 3.8 9.3 9.2 7.2 7.4 5.8 11.5 13.6 4.6 6.7 3.3 6.5 4.0 5.0 5.4 8.2 9.4 8.5 5.6 8.8 4.9 1.5 5.6 1.9 9.8 8.9 15.4 7.2 10.2 9.9 6.5 7.2 11.3 11.0 0.9 6.6 6.8 5.5 10.3 6.3 10.3 14.8 31.6 12.4 10.9 7.3 13.6 10.1 11.6 16.6 0.0 6.4 7.0 10.7 6.2 14.7 3.1 0.0 9.4 6.8 7.0 2.0 33.3 3.3 5.7 0.8 5.2 13.7 0.0 4.6 11.1 7.0 7.0 10.4 3.9 8.7 4.8 7.5 6.7 6.4 0.6 10.0 6.9 6.8 9.0 12.3 11.8 3.3 14.0 11.3 7.0 18.5 12.9 7.1 7.1 11.1 4.6 18.5 12.9 12.5 6.4 NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 44.1" "Cell type enhanced" "Detected in some" 17 "Bipolar cells: 15.8;Early spermatids: 37.5;Horizontal cells: 66.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 12 "monocytes: 2.4" "Cell line enhanced" "Detected in some" "CACO-2: 20.0;SH-SY5Y: 6.7;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA060820: AB_2684373, HPA065419: AB_2685487" "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" 7.7 13.0 5.3 1.8 9.9 1.1 3.1 2.1 9.8 7.8 2.1 3.7 2.8 1.3 10.3 5.4 1.8 4.7 3.7 2.5 5.5 7.4 2.7 1.7 2.8 1.6 6.5 5.0 12.9 2.5 0.9 44.1 8.8 11.9 5.2 2.2 5.8 1.9 3.7 2.1 1.5 2.1 3.5 6.2 4.4 1.8 16.6 7.4 0.0 1.7 1.7 1.2 1.8 3.8 0.0 0.1 0.0 2.4 0.0 0.1 0.1 0.1 0.2 1.9 0.1 0.6 0.1 2.4 0.1 0.1 0.1 0.0 20.0 0.7 0.3 0.2 0.0 0.3 0.3 1.4 0.0 0.0 0.0 0.4 1.9 0.4 1.8 0.2 0.1 0.1 2.3 0.0 0.0 0.0 0.6 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.3 1.9 0.5 0.2 0.3 0.0 0.2 0.0 0.0 0.2 6.7 0.0 0.2 0.0 4.9 0.2 0.4 2.6 0.1 1.6 0.4 0.3 1.1 0.3 0.3 0.7 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 0.1 5.3 9.9 2.1 9.8 5.5 7.4 6.5 5.0 11.9 7.4 0.0 0.0 0.0 0.1 0.2 15.8 0.8 2.5 0.0 1.2 0.0 0.0 0.8 0.0 0.0 37.5 0.7 0.0 0.0 0.0 0.5 3.4 0.2 0.0 0.0 0.3 66.7 0.0 1.3 5.4 13.2 10.3 0.2 0.0 0.0 0.0 10.1 0.0 0.0 13.8 0.0 2.3 0.0 4.7 0.3 4.4 0.0 0.7 0.0 0.0 0.0 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058549 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "blood: 49.5;intestine: 123.4" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 39.3;monocytes: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 49.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.4;fHDF/TERT166: 6.8;HHSteC: 19.0;HSkMC: 12.5;SCLC-21H: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047123 Enhanced Uncertain Cytosol NA NA Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 4.1 0.9 1.4 3.3 1.6 7.0 4.1 1.9 1.4 6.0 54.3 1.2 2.6 7.8 7.2 1.8 2.7 4.4 3.4 3.5 1.3 0.6 2.3 1.2 3.4 5.2 1.5 1.5 6.2 1.0 0.9 2.0 1.5 1.6 4.6 2.6 3.1 2.3 4.8 2.0 1.6 123.4 4.3 1.4 5.0 2.8 1.8 1.2 1.8 1.8 2.3 2.9 3.1 5.4 8.8 4.9 49.5 6.3 22.2 12.9 7.0 0.0 0.0 0.1 0.2 0.5 5.4 0.9 2.0 0.0 2.5 1.1 0.0 0.0 0.1 0.0 6.8 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.0 0.1 3.1 19.0 0.0 0.0 12.5 0.0 2.5 0.0 0.0 3.2 0.1 0.0 0.2 0.0 0.2 0.2 0.6 0.0 0.0 0.1 0.1 0.0 0.8 0.2 0.0 9.8 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.7 0.0 0.1 0.1 49.5 6.3 10.3 9.5 4.3 4.9 8.0 7.6 4.8 4.9 8.8 8.8 4.9 1.1 22.2 2.5 0.2 12.9 7.0 1.4 1.6 1.9 1.4 1.3 0.6 1.5 1.5 1.6 1.2 0.0 0.0 8.2 3.2 3.2 1.1 1.1 2.5 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.6 9.0 39.3 0.0 0.7 0.2 5.7 0.5 19.6 0.0 2.8 9.5 1.2 16.5 7.6 1.7 10.9 6.4 15.1 22.6 0.7 10.8 0.3 14.4 17.0 0.0 0.9 0.0 13.7 1.6 2.6 2.9 0.3 11.7 0.4 0.3 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058354-42070842 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hofbauer cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "classical monocyte: 38.5;intermediate monocyte: 47.6;myeloid DC: 37.9;non-classical monocyte: 46.1;plasmacytoid DC: 23.2" "Group enriched" "Detected in all" 9 "dendritic cells: 37.9;monocytes: 47.6" "Cell line enhanced" "Detected in all" "HMC-1: 66.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" NA NA 2300000 "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 23.7 13.5 12.1 20.3 14.5 11.3 12.5 11.8 10.3 16.3 18.3 15.0 10.7 13.2 18.9 16.1 14.5 17.3 16.5 15.8 10.1 8.6 17.9 28.2 19.9 32.6 12.6 7.3 18.1 9.5 27.8 13.1 45.3 11.5 15.2 18.0 19.8 16.6 14.5 9.2 9.9 25.6 18.7 11.4 22.0 14.1 9.3 13.2 12.0 15.0 11.4 17.9 17.3 14.5 2.1 37.9 4.9 47.6 3.4 3.4 19.2 9.2 4.7 7.5 13.4 13.1 15.1 5.5 7.6 15.7 13.2 13.8 10.5 13.6 4.5 4.7 16.6 8.0 6.5 5.7 9.3 7.9 10.3 7.2 11.2 7.3 7.1 7.7 9.2 66.6 10.3 8.2 11.8 5.0 6.8 21.8 3.9 4.0 19.3 10.4 10.7 3.4 3.8 2.0 8.4 6.3 7.6 3.8 8.0 10.2 11.0 2.3 2.6 10.1 9.3 10.0 6.9 13.9 17.1 11.7 9.3 11.4 5.9 6.9 10.7 10.7 3.6 9.9 17.7 11.4 4.9 38.5 4.6 2.8 47.6 2.8 2.1 2.9 2.6 37.9 1.5 1.9 1.8 1.9 3.4 46.1 23.2 3.4 19.2 12.1 14.5 11.8 10.3 10.1 8.6 12.6 7.3 11.5 13.2 8.9 7.0 6.7 6.8 3.0 2.8 3.4 5.1 16.0 7.9 7.0 7.9 40.8 3.3 14.3 9.9 6.0 26.2 23.3 7.2 55.8 12.9 7.8 9.2 29.8 80.8 0.0 5.8 9.2 52.1 12.0 6.6 49.9 18.6 47.7 13.7 5.6 11.1 19.5 6.3 8.4 5.7 19.4 12.3 10.5 5.3 3.0 48.7 7.7 12.1 8.6 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536172-42544449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease mutation, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" NA NA 300000000 "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favorable (4.17e-4)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favorable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 21.1 21.0 10.2 8.4 15.9 10.7 18.3 5.5 11.4 16.9 17.1 19.1 16.3 14.8 19.3 20.6 11.9 14.6 21.4 11.5 10.7 5.9 31.3 50.1 16.3 12.5 21.6 8.0 20.4 38.9 10.6 12.7 23.5 12.1 14.8 10.2 20.9 32.4 12.3 9.1 13.2 17.3 10.1 13.5 22.5 17.0 9.8 20.5 8.9 20.7 8.9 12.3 16.1 12.7 4.8 6.0 3.8 5.8 4.3 5.8 2.4 6.0 21.1 4.2 9.6 42.1 14.0 14.3 9.2 21.9 9.7 12.4 5.7 15.6 7.7 9.4 14.1 21.5 14.7 3.8 4.4 2.2 5.9 7.8 4.2 10.9 11.7 14.1 5.0 10.9 16.6 6.9 5.3 6.6 10.7 12.6 1.4 6.1 15.6 10.7 14.5 0.8 8.6 4.9 12.9 2.7 3.2 9.2 17.9 12.8 13.9 6.4 9.7 5.0 6.9 7.8 6.4 32.1 5.3 9.8 23.6 3.9 9.3 5.9 20.8 9.3 6.4 14.4 5.5 16.7 2.3 5.5 3.8 5.6 3.7 5.8 4.8 2.4 3.1 4.5 4.6 4.3 3.5 2.5 4.3 5.8 6.0 0.5 2.4 10.2 15.9 5.5 11.4 10.7 5.9 21.6 8.0 12.1 20.5 11.9 8.5 6.7 5.2 2.5 13.3 3.9 20.4 0.0 2.3 17.4 3.9 19.9 3.3 13.8 0.2 8.7 20.2 0.0 28.2 11.7 13.8 9.4 2.3 35.8 31.7 14.3 6.4 28.3 21.0 1.9 18.4 10.9 15.1 5.4 15.9 12.0 16.3 2.9 12.0 31.2 6.4 6.5 8.2 0.4 5.3 3.0 15.4 5.0 10.2 4.7 NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved NA NA 3600000 "HPA064055: AB_2685183" "unprognostic (9.93e-2)" "unprognostic (1.61e-2)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (7.12e-3)" "unprognostic (3.30e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-3)" "unprognostic (9.41e-2)" "prognostic unfavorable (2.67e-5)" "unprognostic (1.26e-1)" "unprognostic (6.09e-2)" "unprognostic (7.47e-2)" "unprognostic (1.02e-1)" 8.3 6.3 9.9 9.0 20.1 8.7 4.7 4.7 25.0 6.8 8.5 4.6 5.8 11.4 6.2 4.7 6.1 4.8 5.6 5.0 15.3 5.3 7.2 7.6 7.6 9.1 5.0 9.5 4.2 7.3 7.6 4.9 6.8 6.6 4.9 5.1 4.0 6.0 6.2 6.7 8.5 9.2 5.5 4.4 10.9 12.4 2.7 5.5 4.3 5.1 2.6 5.6 6.0 4.4 9.5 26.5 5.1 20.9 5.1 9.9 9.7 1.5 6.0 1.0 6.5 2.6 3.4 6.8 4.5 8.0 5.9 7.4 5.0 12.5 0.6 5.7 6.1 10.2 4.6 2.7 5.0 1.8 7.3 8.4 2.2 3.9 32.2 8.3 5.3 9.5 5.1 5.2 3.9 1.7 7.4 9.1 5.6 6.9 8.9 3.6 6.8 2.4 14.4 3.2 3.8 6.4 6.5 2.4 11.8 3.8 2.4 2.6 3.5 3.6 8.9 9.1 1.0 6.1 6.6 6.7 6.5 4.7 15.1 3.3 4.9 3.8 1.4 3.0 8.2 5.4 1.2 20.9 5.1 9.9 18.2 7.9 9.5 9.8 8.8 26.5 8.3 8.1 7.4 0.6 5.1 11.7 6.8 8.7 9.7 9.9 20.1 4.7 25.0 15.3 5.3 5.0 9.5 6.6 5.5 0.0 2.4 13.7 4.8 2.6 13.3 1.5 7.6 4.0 3.4 5.2 29.5 11.3 1.7 10.2 0.2 6.7 17.1 0.0 7.5 12.5 3.2 3.7 1.1 7.3 25.0 15.9 1.2 8.6 17.2 0.9 7.5 19.1 3.3 25.2 9.9 5.4 8.5 14.4 6.0 7.4 12.5 0.0 3.1 4.4 8.1 2.0 7.9 13.8 10.6 2.1 NANP "C20orf147, dJ694B14.3, HDHD4, MGC26833" ENSG00000170191 "N-acetylneuraminic acid phosphatase" Q8TBE9 20 25612935-25624175 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050342 Uncertain Approved "Nuclear membrane" NA NA "Nuclear membrane" "HPA050342: AB_2681098" "unprognostic (8.72e-2)" "unprognostic (1.88e-1)" "unprognostic (7.42e-3)" "unprognostic (6.01e-2)" "unprognostic (5.59e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (9.01e-6)" "unprognostic (3.20e-1)" "unprognostic (3.75e-2)" "unprognostic (7.70e-3)" "unprognostic (1.24e-1)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-1)" "unprognostic (1.71e-2)" "unprognostic (9.42e-2)" 10.0 14.0 6.3 6.0 7.4 6.9 7.2 13.3 8.2 6.3 6.4 4.1 4.3 7.1 6.9 5.7 9.5 6.2 6.2 6.8 4.3 4.8 11.6 12.5 6.7 4.4 4.2 3.3 12.0 7.4 8.0 8.6 6.0 6.5 5.6 6.2 7.1 7.8 6.1 9.2 4.9 7.6 6.9 5.6 7.1 6.2 6.6 3.7 18.2 9.0 6.0 6.8 7.4 6.8 1.7 6.4 1.7 4.5 4.9 4.2 2.3 11.1 6.5 5.3 7.7 8.6 9.2 7.8 5.7 11.2 7.6 9.8 5.9 7.7 4.0 6.5 10.8 9.0 7.1 8.1 8.2 14.8 1.4 4.8 10.0 3.1 15.7 7.2 7.6 3.0 8.0 4.1 8.5 10.9 4.2 6.4 13.8 8.4 7.2 9.2 6.1 15.0 3.8 3.9 9.7 10.2 7.5 11.2 4.9 4.4 6.0 10.2 4.2 6.3 10.2 6.7 5.6 4.4 6.5 5.4 12.1 9.0 11.1 8.0 3.8 3.5 10.0 3.4 17.7 7.2 0.4 4.5 1.7 2.8 4.5 4.2 1.4 2.0 2.1 6.4 1.7 1.8 3.1 0.3 4.9 2.4 1.4 1.7 2.3 6.3 7.4 13.3 8.2 4.3 4.8 4.2 3.3 6.5 3.7 3.0 1.0 1.5 3.4 5.3 4.6 3.1 5.1 0.0 2.3 7.0 0.0 3.4 11.6 4.4 0.3 4.5 1.3 0.0 3.7 1.6 4.6 2.4 5.7 4.9 3.9 6.4 2.9 4.3 2.5 0.0 2.8 3.7 5.0 1.0 2.6 5.6 4.4 2.0 2.5 7.1 6.8 0.0 3.9 2.6 10.7 4.4 1.6 1.5 2.5 2.3 NAPEPLD "C7orf18, FMP30, NAPE-PLD" ENSG00000161048 "N-acyl phosphatidylethanolamine phospholipase D" Q6IQ20 7 103099776-103149560 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 74.1;Early spermatids: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019832, HPA024338" Approved Approved Cytosol NA NA Cytosol "HPA019832: AB_1844422, HPA024338: AB_2671533" "unprognostic (3.62e-1)" "unprognostic (1.86e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.58e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" "unprognostic (6.39e-3)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.81e-2)" "unprognostic (3.21e-1)" "prognostic favorable (7.32e-6)" "unprognostic (8.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" "unprognostic (2.41e-2)" 3.8 5.3 8.6 3.8 14.0 3.1 3.9 13.9 18.5 5.1 8.8 17.2 3.7 15.9 4.9 3.5 2.6 6.5 6.1 4.2 6.4 5.5 15.1 7.4 4.3 3.8 15.0 11.6 9.7 4.1 8.5 6.2 2.9 10.3 5.4 10.1 5.0 4.2 4.1 5.0 5.7 10.8 4.5 9.7 6.6 11.2 11.1 16.7 5.3 8.8 0.9 3.8 6.9 4.6 7.9 3.7 5.7 4.6 2.9 7.6 2.5 4.6 6.2 4.0 3.6 3.6 3.9 0.6 3.0 2.8 2.1 3.4 2.7 6.2 4.2 5.1 2.3 4.7 4.3 2.8 1.0 2.5 6.5 3.9 1.7 3.7 1.2 0.9 3.7 1.8 2.2 1.2 1.9 0.0 7.8 3.4 3.0 2.0 4.5 4.0 1.7 4.4 2.0 3.7 7.3 7.3 2.8 1.8 2.2 7.6 2.1 2.9 3.9 8.2 2.6 1.8 2.2 1.7 2.1 3.0 5.9 4.2 12.0 3.7 5.6 6.1 3.6 4.2 2.7 11.3 0.2 3.1 5.7 4.9 4.6 4.4 7.4 5.3 5.8 3.7 7.9 7.6 5.6 0.3 2.9 3.0 2.7 4.7 2.5 8.6 14.0 13.9 18.5 6.4 5.5 15.0 11.6 10.3 16.7 17.9 7.7 9.8 4.8 6.0 74.1 10.2 20.4 1.4 6.8 50.6 49.1 7.3 8.3 4.4 112.3 2.9 30.7 0.0 2.3 3.1 4.6 8.5 4.6 18.4 3.5 47.7 13.3 4.9 3.5 31.4 29.4 2.7 13.5 4.6 26.3 21.0 3.7 28.6 31.5 26.7 34.0 6.5 2.3 14.6 10.9 2.5 2.4 4.3 23.0 5.5 NAV2 "FLJ10633, FLJ11030, FLJ23707, HELAD1, KIAA1419, POMFIL2, RAINB1" ENSG00000166833 "Neuron navigator 2" Q8IVL1 11 19350724-20121598 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 64.6" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 1: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 34.8;SH-SY5Y: 31.8;TIME: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011755, HPA011891" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA011755: AB_1854319, HPA011891: AB_1854318" "unprognostic (7.71e-2)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (3.01e-2)" "unprognostic (3.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (1.84e-1)" "unprognostic (2.83e-2)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (6.43e-2)" "unprognostic (3.28e-2)" 14.8 3.1 7.9 4.7 12.5 3.1 13.8 13.8 16.1 10.2 17.6 16.1 8.6 5.1 9.3 13.4 7.8 5.7 3.2 64.6 9.9 7.0 12.3 18.7 11.2 3.0 16.5 11.5 4.7 10.8 10.1 6.6 16.2 23.5 7.9 6.3 8.6 16.5 11.8 3.4 7.9 4.7 13.0 32.2 2.5 9.9 2.1 12.6 0.0 20.1 1.8 5.3 6.0 8.6 0.3 1.9 0.0 0.5 0.0 0.3 0.0 5.9 1.7 3.9 0.4 13.2 8.5 4.2 5.0 8.6 6.6 5.0 6.7 0.8 0.0 0.2 7.5 10.8 0.7 0.2 3.9 7.8 1.0 0.4 0.1 8.8 7.6 2.4 0.0 0.2 5.5 10.2 3.1 34.8 4.9 8.8 0.0 0.7 3.0 19.1 6.3 0.0 0.0 9.2 1.6 5.0 0.0 18.0 0.9 5.7 1.7 6.8 31.8 3.8 3.0 5.7 21.5 0.1 0.0 24.5 15.5 2.3 18.3 4.7 1.0 0.5 0.0 5.3 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 1.9 0.0 0.0 7.9 12.5 13.8 16.1 9.9 7.0 16.5 11.5 23.5 12.6 59.6 16.9 0.8 19.9 3.8 1.7 12.3 10.2 25.4 25.0 19.2 0.0 22.2 11.6 17.9 2.4 10.8 1.0 0.0 18.3 18.1 14.6 23.3 1.1 33.0 8.6 25.4 10.4 11.1 1.5 5.6 0.9 2.3 15.1 1.8 7.7 32.7 26.8 0.0 3.9 0.4 2.1 0.0 9.0 1.5 0.5 3.1 12.2 0.0 8.0 15.2 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862906 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 86000 Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 10.5 30.2 8.6 9.4 11.1 5.2 10.5 15.5 14.6 13.4 14.1 7.4 16.1 14.1 9.8 13.9 9.0 8.3 16.1 9.8 8.0 9.5 29.7 24.2 16.1 7.2 9.4 6.6 12.7 20.6 13.6 16.5 19.8 10.3 15.1 9.1 14.7 18.1 13.8 10.0 9.1 23.5 9.8 4.7 13.4 12.7 6.5 10.0 5.8 22.7 7.0 9.6 13.6 9.5 4.2 7.7 15.2 13.4 3.0 5.1 7.4 2.4 2.4 2.4 5.6 8.2 3.1 4.8 2.2 7.5 6.5 9.6 14.1 2.6 0.8 5.7 2.9 38.4 1.3 5.1 2.0 2.5 2.0 3.4 1.2 1.4 16.5 14.7 1.5 6.9 5.1 3.8 7.9 4.1 3.9 5.8 1.6 2.6 5.8 3.3 4.3 1.2 2.3 1.9 4.3 1.9 1.7 1.3 8.5 10.8 5.2 1.8 1.1 2.4 3.3 5.8 3.2 6.2 7.1 2.4 4.3 2.5 6.0 3.9 7.2 11.5 1.7 3.1 3.9 3.0 6.4 13.4 8.7 5.1 10.3 4.2 3.9 3.9 4.1 7.7 4.2 4.0 3.9 15.2 3.0 9.2 4.3 4.8 7.4 8.6 11.1 15.5 14.6 8.0 9.5 9.4 6.6 10.3 10.0 23.8 47.7 44.6 42.4 30.5 24.5 18.7 38.2 10.7 17.0 45.4 23.6 52.4 8.3 82.1 0.8 27.6 80.5 0.0 51.5 49.0 63.2 112.7 66.9 21.3 139.8 9.5 108.9 26.4 42.3 0.7 25.6 53.4 67.4 25.2 37.4 48.4 45.4 80.7 21.9 55.3 29.8 25.8 42.2 5.0 7.5 36.4 164.8 28.7 38.6 31.8 NEU2 SIAL2 ENSG00000115488 "Neuraminidase 2" Q9Y3R4 2 233032672-233035057 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "skin 1: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 1.1;BEWO: 1.6;PC-3: 3.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.2;hippocampal formation: 1.1" CAB022336 Uncertain NA NA 9000 "CAB022336: " "unprognostic (1.30e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NEU3 ENSG00000162139 "Neuraminidase 3" Q9UQ49 11 74988134-75018893 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.6" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 58.9;Spermatocytes: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038729, HPA070381" Approved Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA038729: AB_2676179, HPA070381: " "unprognostic (1.67e-1)" "unprognostic (2.10e-1)" "unprognostic (2.55e-2)" "unprognostic (1.13e-3)" "unprognostic (2.95e-2)" "unprognostic (5.42e-2)" "unprognostic (1.63e-1)" "unprognostic (5.11e-2)" "unprognostic (3.91e-3)" "unprognostic (8.50e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.57e-3)" "unprognostic (3.80e-2)" "unprognostic (3.79e-1)" "unprognostic (2.38e-1)" "unprognostic (3.73e-1)" "unprognostic (1.84e-1)" 5.4 13.4 3.7 10.5 6.9 17.0 5.4 7.9 9.1 4.0 3.9 3.0 4.1 3.6 5.4 4.8 3.9 4.4 3.6 5.9 4.0 4.5 4.3 6.7 8.7 9.0 3.8 6.6 7.2 7.3 15.1 11.2 3.1 4.2 9.7 5.4 5.6 4.8 4.6 19.1 6.7 4.7 4.0 3.5 5.5 5.1 44.6 3.0 19.0 6.8 3.5 7.5 4.5 3.1 3.2 3.8 5.8 6.4 1.2 4.2 2.2 4.6 4.0 3.4 6.6 2.6 2.5 3.8 4.5 2.9 5.2 4.0 13.7 3.9 13.3 4.6 3.6 6.6 4.3 8.2 5.8 7.9 7.0 4.4 10.9 7.4 5.6 2.9 17.2 10.6 3.0 4.9 5.2 8.1 3.4 3.7 19.0 17.7 10.0 5.9 5.0 16.9 8.9 4.2 9.1 5.4 14.8 9.0 11.7 6.4 4.9 6.3 4.0 6.9 4.6 20.2 4.2 9.8 4.4 5.6 6.5 6.5 4.3 4.5 8.2 8.0 26.6 1.9 8.9 5.5 2.1 6.4 5.8 4.1 3.7 3.0 2.8 3.2 3.9 3.8 3.2 3.5 4.2 3.3 1.2 4.6 2.7 2.3 2.2 3.7 6.9 7.9 9.1 4.0 4.5 3.8 6.6 4.2 3.0 3.0 5.8 2.2 1.8 0.5 7.2 7.3 2.5 2.7 4.5 1.8 58.9 1.8 0.0 1.0 5.7 1.6 1.3 0.0 2.6 1.2 1.5 2.7 1.1 7.2 4.8 11.1 6.9 4.3 8.6 5.3 1.4 4.5 0.0 4.6 2.9 2.9 2.7 0.0 1.8 3.3 5.8 0.0 2.2 32.5 1.7 0.5 1.1 3.5 3.2 0.4 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241808825-241817413 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 27.1;liver: 42.9" "Cell type enhanced" "Detected in some" 14 "Enterocytes: 65.6;Hepatocytes: 117.5;Intestinal endocrine cells: 33.1;Mucus-secreting cells: 40.3;Paneth cells: 66.2;Undifferentiated cells: 40.1" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "Hep G2: 22.5;HMC-1: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037394 Enhanced NA NA "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.6 0.5 6.5 0.7 5.3 5.7 0.3 1.9 7.0 0.6 13.9 4.9 0.0 9.3 0.3 0.3 0.7 1.1 2.6 0.6 6.4 5.8 1.4 42.9 0.4 0.5 6.9 4.4 0.4 0.3 0.3 0.4 0.4 3.8 0.5 6.1 0.0 0.4 0.4 3.6 0.3 27.1 0.4 4.1 0.5 0.5 0.6 2.3 0.0 0.4 2.8 0.3 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.5 0.0 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 5.3 1.9 4.0 6.4 5.8 6.9 4.4 3.8 2.3 0.0 0.0 0.9 0.0 0.0 0.7 0.5 0.0 0.0 0.0 1.8 0.0 0.0 3.3 0.0 0.0 0.0 65.6 0.0 0.0 0.0 0.2 0.0 1.1 117.5 1.2 0.0 33.1 0.6 3.2 0.0 0.6 0.7 0.0 0.0 40.3 26.2 0.0 66.2 0.7 8.6 1.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 40.1 0.1 NGLY1 "FLJ11005, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 518.0;Late spermatids: 684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" NA NA "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" 10.7 14.4 11.4 19.6 11.4 12.9 15.0 17.1 15.0 9.5 12.4 6.9 11.7 10.5 10.2 13.8 13.2 8.4 10.5 14.3 12.0 9.0 12.8 18.1 13.9 17.4 9.5 12.5 10.6 20.7 9.0 11.3 8.7 11.0 10.9 15.2 7.8 12.4 18.0 46.6 9.0 11.2 8.7 10.1 14.6 11.9 42.0 9.0 18.0 10.3 10.9 18.1 11.5 10.6 26.1 39.7 19.9 10.8 22.6 14.7 10.3 12.5 10.7 6.0 12.7 11.6 10.7 8.6 10.8 9.1 13.6 12.3 6.6 9.6 31.9 12.3 9.1 14.1 5.7 20.2 5.7 18.5 15.0 8.6 23.7 8.2 10.7 13.0 21.8 13.0 9.5 7.6 14.9 14.0 14.8 14.5 15.7 22.4 23.0 13.8 5.5 25.9 12.9 8.1 14.7 19.5 26.5 7.9 22.7 12.5 15.4 3.7 4.5 15.6 15.1 10.0 12.0 14.3 18.3 9.8 10.7 11.1 12.9 13.9 28.3 24.4 22.2 12.9 23.7 8.4 19.9 10.8 18.9 13.7 10.1 14.7 26.1 13.8 12.6 16.3 21.7 14.0 13.6 12.8 22.6 8.4 39.7 10.4 10.3 11.4 11.4 17.1 15.0 12.0 9.0 9.5 12.5 11.0 9.0 17.9 12.9 39.7 20.7 11.2 21.6 22.4 22.9 28.1 15.9 5.2 11.8 36.2 29.9 26.6 518.0 20.1 20.2 0.0 38.1 28.0 19.8 22.0 19.7 22.7 21.1 11.1 6.9 15.4 16.4 684.0 13.8 24.8 23.6 20.8 27.3 19.8 25.0 24.6 14.9 29.8 20.4 0.0 14.6 73.4 43.7 12.0 47.4 33.3 28.9 19.0 NIT2 ENSG00000114021 "Nitrilase family member 2" Q9NQR4 3 100334701-100361635 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 41.1" "Cell type enhanced" "Detected in many" 10 "Proximal tubular cells: 436.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036999, HPA041289" Approved Supported Centrosome,Cytosol NA NA 960000 Cytosol Centrosome "HPA036999: AB_10672105, HPA041289: " "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.06e-3)" "prognostic unfavorable (4.62e-4)" "unprognostic (6.28e-2)" "unprognostic (2.10e-1)" "unprognostic (4.56e-1)" "unprognostic (1.12e-1)" "unprognostic (6.60e-3)" "unprognostic (2.21e-1)" "unprognostic (6.68e-2)" "unprognostic (7.92e-2)" "unprognostic (1.37e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (8.26e-2)" "unprognostic (1.47e-3)" 9.9 7.4 6.7 5.4 9.9 5.9 12.4 3.7 10.5 6.4 7.2 6.1 10.6 5.5 6.6 13.3 9.2 7.9 7.1 7.4 5.8 6.3 29.8 41.1 5.6 8.9 5.9 8.0 7.2 8.5 4.7 7.6 4.9 7.7 7.2 6.8 11.3 8.2 10.2 14.7 7.7 5.3 7.0 5.4 5.7 6.8 3.3 3.3 4.4 10.8 14.5 10.5 8.2 5.6 4.2 5.9 1.5 2.4 3.0 4.3 1.3 9.9 9.9 1.2 5.2 8.9 12.1 6.2 4.1 6.1 9.7 9.3 8.4 11.2 10.0 6.2 5.9 4.2 7.5 4.5 11.0 11.6 3.1 2.3 7.2 3.2 4.3 10.9 4.7 4.9 7.6 16.8 5.2 8.5 5.1 6.2 5.7 3.3 8.1 11.8 9.5 3.1 4.3 4.4 12.5 15.1 3.5 4.2 9.8 16.0 6.3 6.9 3.2 5.6 9.6 6.1 3.3 7.1 4.5 4.5 6.1 2.5 2.9 3.5 5.0 5.5 8.5 9.6 8.0 7.7 0.4 2.4 1.1 3.3 2.1 4.3 4.2 3.1 2.5 5.9 3.7 3.6 3.5 1.5 3.0 1.6 1.8 3.1 1.3 6.7 9.9 3.7 10.5 5.8 6.3 5.9 8.0 7.7 3.3 11.9 12.1 26.5 41.3 29.0 11.3 49.4 30.6 38.8 26.1 55.8 15.7 80.0 159.2 63.8 2.3 15.5 14.9 0.0 46.2 64.1 34.7 40.0 20.7 147.3 56.1 12.7 23.1 16.0 18.8 2.4 40.9 33.3 47.2 136.1 20.8 11.7 55.0 25.7 35.3 436.2 23.6 38.8 46.4 1.5 14.5 36.4 49.5 26.2 34.7 40.6 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722196-65871725 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.7;intermediate monocyte: 5.9;myeloid DC: 4.1;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;monocytes: 5.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 53000 Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 4.5 2.4 7.6 4.7 10.5 2.9 7.3 2.8 11.9 4.1 6.8 5.8 1.0 2.4 5.8 5.0 5.2 3.3 2.7 5.1 7.2 7.6 7.5 18.9 3.4 5.1 8.7 8.5 4.0 11.0 3.6 2.4 4.9 9.8 5.4 6.5 2.0 4.3 2.6 15.0 5.7 5.3 5.5 10.9 5.8 7.5 2.4 6.2 1.8 5.5 7.9 4.0 4.3 3.3 0.9 4.1 0.6 5.9 0.9 0.7 1.8 9.2 8.9 5.3 8.7 6.7 11.5 10.6 9.4 4.0 5.5 6.0 5.1 5.5 13.2 11.9 11.2 11.1 7.4 6.8 14.4 9.7 3.9 4.6 3.6 6.7 12.8 5.8 8.3 2.2 8.7 7.9 7.6 9.1 4.7 15.5 5.9 7.8 2.8 11.9 7.1 5.7 7.5 16.1 4.7 2.6 6.7 11.2 20.9 9.1 4.1 16.4 8.5 7.6 7.8 7.7 14.9 9.3 9.9 8.9 3.7 4.4 5.4 7.0 2.4 4.8 5.8 5.7 16.4 5.5 0.2 4.7 0.2 0.2 5.9 0.3 0.9 0.4 0.3 4.1 0.9 0.7 0.5 0.6 0.9 4.1 0.2 0.1 1.8 7.6 10.5 2.8 11.9 7.2 7.6 8.7 8.5 9.8 6.2 6.0 3.2 1.5 5.1 5.0 0.6 13.2 10.2 2.7 11.4 12.2 3.9 5.2 5.0 15.3 0.2 5.0 20.6 0.0 12.3 12.1 5.2 8.8 15.0 26.4 24.7 4.8 1.7 5.5 23.4 0.0 4.0 8.4 1.7 2.8 7.1 13.2 23.5 10.7 2.1 17.4 3.5 0.0 3.1 1.4 4.3 4.5 2.4 0.9 7.1 5.5 NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015789-139045939 "Enzymes, Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.7" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 8.9;Cone photoreceptor cells: 13.7;Extravillous trophoblasts: 7.7;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: AB_2668640, HPA053714: AB_2682238" "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavorable (6.23e-4)" 17.5 3.9 3.3 4.9 8.0 38.7 7.4 3.2 7.3 2.7 3.1 2.7 0.0 2.2 2.8 1.5 4.0 2.5 7.9 5.4 4.9 3.7 6.9 25.8 5.1 3.1 3.0 3.1 1.7 4.4 4.0 4.7 9.3 3.7 2.0 2.8 1.8 10.8 1.4 12.0 3.9 10.5 4.5 2.3 3.2 3.0 4.9 2.6 3.7 2.9 11.8 3.9 3.7 4.6 1.9 1.5 6.3 3.1 1.4 2.4 0.2 4.7 5.5 2.2 4.1 5.0 2.1 13.5 7.1 5.1 10.1 7.3 7.3 2.0 15.8 5.7 5.3 14.3 3.4 11.4 6.2 9.6 7.0 4.6 7.3 3.3 6.4 4.5 10.7 4.3 2.4 3.1 11.2 7.6 2.0 4.4 3.2 13.1 5.2 4.5 5.4 7.3 5.6 7.0 2.1 5.9 6.0 6.4 5.6 6.8 3.1 8.2 5.5 4.5 5.1 4.0 8.9 3.7 8.3 6.6 5.5 7.1 5.2 8.4 4.3 4.0 10.0 5.1 21.2 6.9 1.5 1.4 0.8 2.4 1.5 1.4 1.1 1.1 1.3 0.6 1.9 0.8 1.6 6.3 1.4 3.1 1.5 0.7 0.2 3.3 8.0 3.2 7.3 4.9 3.7 3.0 3.1 3.7 2.6 8.9 0.6 0.0 2.6 0.0 4.7 0.0 2.5 1.4 1.2 0.0 13.7 4.3 1.7 1.9 0.6 0.0 0.3 0.0 0.2 7.7 0.5 2.0 2.3 1.5 1.4 1.6 0.0 0.6 2.2 0.0 0.9 0.7 0.0 0.0 0.1 0.3 1.8 0.0 0.0 3.1 4.6 0.0 0.0 0.9 3.2 0.0 10.1 0.0 0.0 1.7 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 127.4" "Cell type enriched" "Detected in some" 47 "Extravillous trophoblasts: 865.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 96.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 59000 "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.2 0.1 1.1 0.2 1.2 0.1 0.2 0.3 1.0 0.2 0.2 0.2 0.5 0.6 1.0 1.3 0.3 0.2 0.3 0.3 0.5 0.9 0.8 10.4 1.8 0.2 0.7 0.4 0.2 0.2 0.0 0.2 127.4 0.6 0.4 0.0 0.2 0.3 0.2 4.9 2.4 0.2 0.2 0.3 0.3 0.9 3.0 0.5 0.2 0.2 0.3 0.2 1.3 1.3 0.7 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.4 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.5 0.6 96.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 15.6 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.3 0.9 0.4 1.4 0.5 0.0 1.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 1.2 0.3 1.0 0.5 0.9 0.7 0.4 0.6 0.5 0.0 3.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 865.2 2.3 0.0 0.0 0.9 17.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.8 0.0 18.4 0.0 0.0 0.0 NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47623276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 253.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol No No 2100000 Cytosol "HPA021453: AB_2670709, HPA045649: AB_2679406" "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "prognostic favorable (3.39e-5)" "unprognostic (2.66e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.93e-1)" "unprognostic (8.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" 16.0 26.0 27.2 15.9 27.7 11.1 56.1 36.5 33.8 17.1 17.7 9.8 14.6 14.6 16.9 17.1 47.7 17.2 16.3 22.2 24.0 15.6 18.8 11.1 30.3 24.1 16.0 29.7 20.8 16.8 21.2 15.3 17.6 27.2 18.6 20.0 13.3 21.8 16.5 52.3 29.6 17.3 20.4 22.8 15.7 16.2 15.3 16.1 7.0 14.5 14.8 18.1 19.0 30.5 6.9 9.0 23.2 8.6 9.3 9.2 5.4 32.7 21.6 21.8 15.3 25.1 25.4 45.9 14.5 18.8 21.9 21.4 13.9 37.7 19.6 22.4 21.1 19.9 20.0 23.9 13.3 34.2 8.7 20.6 23.5 22.3 16.1 14.5 13.3 15.3 19.4 13.2 15.9 8.4 32.0 22.5 6.8 19.8 11.4 31.1 8.8 17.6 11.9 13.3 18.5 19.6 14.3 30.6 17.3 27.4 24.0 17.4 15.0 18.6 10.9 12.9 38.4 81.1 9.3 28.8 14.7 10.6 21.8 10.1 23.4 22.5 11.9 20.7 7.0 9.6 10.2 8.6 10.7 9.1 6.6 9.2 6.8 7.3 8.5 8.7 6.9 6.5 7.6 23.2 9.3 6.8 9.0 8.4 5.4 27.2 27.7 36.5 33.8 24.0 15.6 16.0 29.7 27.2 16.1 77.4 58.6 28.2 59.7 69.1 136.0 50.0 50.9 29.4 39.8 40.1 253.3 68.9 23.2 54.3 25.4 43.7 53.1 0.0 47.2 63.0 58.6 89.0 39.4 26.9 35.7 106.5 42.6 39.3 44.0 43.4 48.9 38.9 55.6 26.2 41.6 39.6 80.1 54.0 47.0 38.3 167.1 77.6 44.8 47.1 27.9 89.6 87.5 32.0 44.8 147.8 NRDC "hNRD1, hNRD2, NRD1" ENSG00000078618 "Nardilysin convertase" O43847 1 51789191-51878937 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 96.4" "Group enriched" "Detected in many" 8 "Early spermatids: 492.5;Late spermatids: 1318.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053661 Approved Nucleoplasm NA NA Nucleoplasm "HPA053661: AB_2682221" "unprognostic (1.22e-1)" "unprognostic (6.52e-2)" "unprognostic (2.14e-2)" "unprognostic (5.62e-2)" "unprognostic (2.61e-1)" "unprognostic (3.25e-2)" "prognostic unfavorable (5.49e-6)" "unprognostic (1.42e-1)" "unprognostic (4.17e-2)" "unprognostic (1.67e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.12e-9)" "unprognostic (2.75e-1)" "unprognostic (2.35e-2)" "unprognostic (9.54e-2)" "unprognostic (5.53e-3)" 16.4 15.9 13.4 15.8 17.5 14.5 11.7 14.7 16.9 12.2 13.7 11.0 9.9 11.2 11.8 12.1 14.4 10.9 10.9 25.7 13.1 13.3 12.4 28.5 12.0 13.6 16.2 10.6 11.7 15.9 19.3 21.4 14.2 15.7 13.8 12.1 9.8 11.9 11.3 96.4 19.1 10.3 13.3 14.0 13.6 11.9 32.3 14.5 19.4 11.7 21.5 15.1 13.0 16.0 13.8 18.5 36.3 19.1 15.8 15.1 16.2 46.9 26.5 26.6 38.1 28.0 43.3 30.9 47.5 41.1 34.6 36.7 18.5 18.6 31.0 25.4 35.7 46.4 27.4 39.0 36.8 43.8 36.7 19.2 37.0 36.0 16.1 28.7 32.3 28.2 34.4 28.2 50.4 46.8 29.8 35.9 33.0 48.7 20.8 43.2 17.2 29.2 11.2 47.2 19.4 28.5 28.6 31.8 34.2 25.5 27.3 25.5 19.2 43.3 34.9 25.7 53.9 23.3 39.3 29.8 30.4 28.2 33.1 40.3 31.1 46.9 29.0 35.9 40.7 34.8 19.3 18.1 26.0 13.7 19.1 13.7 13.8 12.7 15.1 18.5 9.3 12.5 13.4 36.3 15.8 14.5 15.0 14.4 16.2 13.4 17.5 14.7 16.9 13.1 13.3 16.2 10.6 15.7 14.5 32.8 55.9 17.8 35.3 0.0 67.0 0.0 17.8 108.4 63.7 26.2 76.6 47.3 26.6 38.1 492.5 33.3 18.8 70.0 55.1 37.0 33.6 42.0 32.5 52.9 39.9 58.8 17.5 28.3 38.2 1318.0 61.2 53.3 0.0 60.5 26.4 53.0 45.7 14.0 55.5 15.1 68.3 58.2 0.0 37.6 20.9 0.0 69.0 40.6 27.9 33.4 NSF "SEC18, SKD2" ENSG00000073969 "N-ethylmaleimide sensitive factor, vesicle fusing ATPase" P46459 17 46590669-46757464 "Enzymes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.4" "Cell type enhanced" "Detected in many" 5 "Bipolar cells: 95.1;Cone photoreceptor cells: 82.5;Rod photoreceptor cells: 82.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003154, CAB009324, HPA071089" Enhanced Supported "Golgi apparatus,Cytosol" NA NA 6900 Cytosol "Golgi apparatus" "CAB009324: AB_653479, HPA003154: AB_1079508, HPA071089: AB_2686343" "unprognostic (5.70e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.09e-1)" "unprognostic (3.95e-2)" "unprognostic (5.48e-2)" "unprognostic (2.37e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-2)" "unprognostic (3.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.74e-1)" 1.9 3.6 11.2 2.7 19.1 1.6 2.6 14.1 35.4 2.5 4.0 1.4 1.9 2.7 3.9 2.2 2.8 1.5 13.9 14.4 3.4 2.5 2.2 3.1 12.6 1.3 3.5 6.5 5.5 2.6 2.8 5.5 2.4 2.1 4.3 2.4 3.2 2.2 3.1 1.6 3.0 3.1 3.6 3.4 3.3 1.0 7.2 15.5 10.4 13.3 6.7 11.1 8.8 6.1 13.6 9.1 0.6 5.4 7.6 7.4 8.4 9.9 8.1 7.9 9.3 0.0 15.0 15.1 18.6 8.4 1.1 10.2 3.1 13.3 5.3 13.4 0.5 9.8 12.8 8.0 0.4 3.3 6.9 4.3 16.4 6.9 4.3 12.7 3.8 10.0 8.2 17.9 12.0 10.0 3.9 5.1 19.1 16.2 7.2 8.8 14.0 9.3 12.8 8.4 9.5 12.4 0.0 5.9 10.1 15.6 18.7 10.3 22.9 8.1 12.1 12.6 17.7 10.1 8.9 6.4 8.1 16.1 10.4 13.3 7.8 8.2 12.1 8.9 6.8 8.2 10.5 15.5 7.2 6.9 8.1 6.0 6.7 12.1 6.2 11.1 8.8 8.9 9.9 12.6 3.2 3.5 95.1 6.2 10.2 4.0 7.9 21.0 82.5 10.9 10.0 10.3 26.6 10.6 25.1 0.0 14.0 12.0 9.3 10.6 9.2 18.7 16.9 41.3 29.3 11.6 27.2 34.0 5.5 15.5 10.1 28.9 27.8 21.3 11.7 14.4 8.1 12.2 82.9 0.0 11.7 28.9 31.3 5.0 15.4 10.9 16.1 7.8 NT5C1A "CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201" ENSG00000116981 "5'-nucleotidase, cytosolic IA" Q9BXI3 1 39659121-39672038 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 51.9;tongue: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "SH-SY5Y: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA050283, HPA054158" Supported NA NA "HPA050283: AB_2681072, HPA054158: AB_2682402" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-1)" "unprognostic (1.51e-3)" "unprognostic (7.19e-2)" "unprognostic (2.87e-1)" "unprognostic (3.34e-1)" "unprognostic (1.32e-1)" "unprognostic (3.29e-2)" "unprognostic (1.81e-2)" 0.7 2.8 1.2 0.8 3.0 0.5 0.5 5.6 7.6 0.7 0.5 1.0 0.0 0.5 0.6 2.9 3.0 0.7 0.5 9.8 1.7 1.7 0.9 0.5 0.5 0.5 1.8 4.9 0.7 6.0 0.5 0.5 0.5 6.9 0.9 0.5 0.0 0.7 0.7 51.9 0.5 0.6 0.6 5.2 0.5 0.6 0.7 1.0 0.0 0.5 13.9 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 20.4 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 5.6 7.6 1.7 1.7 1.8 4.9 6.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 52.6" "Group enriched" "Detected in some" 90 "Early spermatids: 137.7;Late spermatids: 218.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA056683 Uncertain NA NA "HPA056683: AB_2683207" "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.3 0.7 0.0 0.4 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 52.6 0.1 0.1 0.5 0.1 0.1 0.5 0.1 1.2 3.7 0.0 0.1 0.7 2.6 0.4 3.2 0.7 0.3 0.0 0.0 0.0 0.5 2.5 0.0 0.0 0.0 0.0 3.5 1.6 0.5 0.0 2.2 1.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.9 0.0 0.6 0.1 0.0 0.0 0.2 0.0 3.3 0.0 0.5 1.1 0.2 0.0 2.9 0.1 0.2 0.6 0.6 1.6 0.3 0.7 0.8 0.1 2.9 2.4 1.2 2.6 0.4 1.5 0.4 0.7 0.7 1.6 1.5 1.0 2.9 0.5 1.0 0.7 2.0 2.5 0.0 1.2 0.0 0.1 0.0 1.3 0.0 2.3 0.1 1.3 1.3 0.3 1.2 2.6 2.2 0.0 0.7 0.1 3.7 0.5 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 137.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 NT5C2 "cN-II, GMP, NT5B, PNT5, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103088017-103193306 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase" "Cancer-related genes, Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved NA NA "HPA003751: AB_1854664" "unprognostic (8.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.55e-2)" "unprognostic (2.46e-1)" "unprognostic (5.54e-2)" "unprognostic (4.87e-3)" "unprognostic (2.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.41e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-3)" "unprognostic (6.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.70e-2)" "unprognostic (6.40e-2)" "unprognostic (3.43e-1)" "unprognostic (1.50e-1)" 15.0 17.0 17.6 18.2 21.2 31.6 19.7 22.5 19.6 17.5 20.7 25.4 24.5 10.9 24.6 19.6 38.6 14.8 17.0 16.5 16.7 20.7 19.6 15.5 18.8 16.8 21.8 17.3 24.8 19.4 18.7 29.5 16.9 29.1 22.9 17.0 26.2 67.2 21.6 41.6 11.7 13.9 20.4 19.1 20.5 15.9 21.7 14.5 29.7 39.2 16.3 31.5 21.1 31.1 6.7 9.7 23.8 14.5 10.5 8.7 7.1 50.7 20.7 14.4 32.3 12.7 14.1 8.3 25.5 24.8 12.4 12.9 15.0 40.7 24.3 19.8 17.6 10.8 26.0 9.5 13.1 14.6 14.6 8.9 17.5 8.8 14.5 22.7 25.3 8.7 21.7 14.6 10.8 17.5 30.2 11.4 11.8 11.3 17.0 21.5 30.0 22.6 32.8 13.6 15.5 25.6 36.9 12.4 7.0 17.8 29.0 4.3 10.8 13.4 10.6 20.0 20.4 16.1 19.7 11.6 9.9 10.0 14.1 18.6 14.9 24.7 32.6 10.0 29.3 2.8 19.8 11.7 23.8 8.1 11.9 8.7 6.7 7.0 6.5 9.7 4.2 6.0 6.2 21.4 10.5 14.5 7.3 6.5 7.1 17.6 21.2 22.5 18.0 16.7 20.7 21.8 17.3 29.1 14.5 77.4 27.5 10.4 26.3 6.5 19.9 2.4 20.4 32.1 67.1 26.2 43.2 16.3 10.0 27.7 82.0 15.7 21.6 0.0 22.4 10.0 11.0 32.1 8.1 14.9 17.8 44.5 11.1 12.3 30.0 49.8 23.0 20.7 25.3 13.6 16.7 78.8 41.7 14.2 12.7 13.9 53.0 32.3 12.6 23.0 21.5 6.6 29.3 16.6 13.3 73.2 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014113-33062797 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010630, HPA029058" Uncertain "Intracellular and membrane" NA NA "HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.3 12.1 9.9 17.0 9.9 15.4 11.4 16.2 12.2 12.0 27.5 7.4 8.1 20.9 14.7 11.6 12.0 9.0 12.9 11.6 9.8 10.3 11.7 10.5 11.6 15.0 10.3 9.8 10.3 19.1 5.5 10.9 10.6 8.4 9.6 27.2 8.5 9.0 8.9 53.3 15.0 19.7 7.5 9.9 18.4 14.5 6.3 8.9 15.4 9.8 28.8 22.8 12.0 11.6 21.4 6.8 36.6 11.4 8.6 18.9 13.3 14.3 10.5 9.8 8.7 7.4 6.5 7.9 15.7 10.3 10.7 14.6 6.5 40.6 36.1 9.1 9.2 18.7 21.9 10.5 10.4 15.9 5.6 13.5 16.4 12.4 9.4 7.9 19.5 13.6 7.2 9.3 11.7 23.5 6.5 7.0 12.4 14.1 9.6 13.2 9.8 7.2 30.6 10.0 17.3 9.2 9.6 8.9 21.3 34.1 15.1 10.5 13.1 10.3 19.4 24.6 8.6 12.9 10.9 6.1 9.1 8.2 15.5 20.5 19.3 22.0 17.7 7.5 12.1 14.2 26.9 8.0 29.8 9.0 10.2 10.2 21.4 12.1 11.0 6.8 20.5 12.4 10.6 36.6 8.6 11.4 6.4 18.9 13.3 9.9 9.9 16.2 12.2 9.8 10.3 10.3 9.8 8.4 8.9 20.8 10.7 82.5 30.5 41.6 22.0 14.0 30.6 37.5 27.3 15.7 39.3 30.8 24.9 25.8 3.2 34.9 102.1 46.7 70.0 25.2 31.9 27.6 17.3 16.3 22.9 1.6 114.8 20.3 26.5 3.6 31.4 25.2 25.3 17.2 74.0 23.6 44.1 98.2 20.8 48.5 23.5 12.9 27.8 30.9 17.2 34.0 23.7 34.5 50.5 60.6 NT5C3B "cN-IIIB, MGC20781, NT5C3L" ENSG00000141698 "5'-nucleotidase, cytosolic IIIB" Q969T7 17 41825181-41836263 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatocytes: 135.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030786, HPA057095" Approved NA NA "HPA030786: AB_10602716, HPA057095: AB_2683333" "unprognostic (3.90e-2)" "unprognostic (5.75e-2)" "unprognostic (8.87e-2)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (8.11e-5)" "unprognostic (3.40e-2)" "unprognostic (6.05e-2)" "unprognostic (2.31e-1)" "prognostic favorable (2.67e-4)" "unprognostic (3.07e-1)" "unprognostic (7.17e-3)" "unprognostic (2.36e-2)" "unprognostic (4.80e-3)" "unprognostic (7.14e-3)" "unprognostic (1.42e-2)" 10.0 12.4 15.9 8.3 26.2 3.2 18.3 22.8 31.2 11.6 15.6 8.4 10.1 4.4 14.1 21.3 13.9 12.6 11.5 11.4 15.0 14.9 19.2 19.4 11.0 7.9 12.9 16.4 15.5 19.6 21.1 13.7 11.5 13.2 12.6 13.8 12.6 15.9 20.1 7.8 8.6 8.1 22.1 6.7 7.7 12.0 24.8 9.8 1.4 37.8 5.6 10.7 13.3 9.7 5.3 5.2 2.5 5.6 1.0 5.9 4.1 8.6 13.0 22.2 29.2 20.4 17.3 3.1 8.7 25.4 27.8 27.8 10.6 5.1 13.0 4.5 17.8 17.4 8.4 22.0 12.3 45.2 6.4 8.7 7.9 13.5 11.2 13.6 0.1 3.3 12.2 11.8 23.5 19.2 20.9 16.1 10.4 7.3 8.1 19.6 5.1 12.6 3.0 5.9 17.2 1.9 10.8 29.6 12.0 12.1 9.4 13.6 7.0 13.1 47.0 4.6 28.9 12.7 4.7 11.0 8.6 6.7 14.3 17.9 1.6 6.6 6.3 11.2 0.2 10.5 1.5 5.6 0.5 3.8 1.0 5.8 4.7 5.9 5.1 5.2 5.3 5.4 4.5 2.5 1.0 0.7 2.7 0.8 4.1 15.9 26.2 22.8 31.2 15.0 14.9 12.9 16.4 13.2 9.8 8.9 15.0 15.7 49.4 16.1 30.4 11.2 7.6 14.7 7.9 27.9 17.7 35.2 86.2 47.9 69.9 21.5 2.5 0.0 36.0 48.9 37.1 35.6 11.5 19.7 11.9 109.7 37.8 19.0 7.9 92.8 30.0 17.0 33.7 5.4 12.5 29.9 37.1 12.9 28.7 45.0 27.3 38.8 52.0 135.0 29.1 15.1 26.1 13.8 14.0 38.3 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Ito cells: 45.4;Pancreatic endocrine cells: 72.9;Rod photoreceptor cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 13.4;memory CD8 T-cell: 6.6;naive B-cell: 19.9;naive CD8 T-cell: 17.3" "Group enriched" "Detected in many" 47 "B-cells: 19.9;T-cells: 17.3" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 93.4;LHCN-M2: 105.7;TIME: 61.2;U-87 MG: 95.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1600000 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 12.2 3.2 9.3 7.7 11.6 0.5 16.6 1.1 6.9 58.8 13.9 3.6 8.1 18.6 33.3 14.8 7.6 12.2 15.4 6.1 5.7 5.5 8.8 26.0 3.4 6.8 6.3 6.6 25.4 1.4 1.6 9.3 42.2 5.3 16.4 15.6 15.3 4.6 17.8 5.7 4.5 14.9 35.3 6.3 7.0 6.0 12.4 4.2 1.6 26.5 7.3 7.1 16.6 20.2 19.9 0.0 0.2 0.0 0.4 17.3 3.9 5.3 2.8 4.9 0.1 11.2 35.7 0.0 34.5 37.8 17.0 32.0 0.0 53.0 0.0 12.4 30.1 43.8 2.7 0.0 34.7 40.6 0.0 0.0 0.0 0.8 0.6 5.6 0.0 0.0 9.1 0.4 34.7 22.1 93.4 14.1 0.0 0.0 0.1 105.7 0.9 0.0 0.0 0.1 0.9 3.8 0.1 1.1 0.1 36.8 2.4 0.0 0.6 0.4 2.1 11.7 0.2 0.0 0.9 61.2 13.9 0.1 17.5 56.1 2.6 1.6 0.0 95.4 0.0 43.5 0.0 0.0 0.2 2.0 0.0 3.5 13.4 2.3 6.6 0.0 19.9 2.4 17.3 0.2 0.4 0.0 0.0 0.8 3.9 9.3 11.6 1.1 6.9 5.7 5.5 6.3 6.6 5.3 4.2 0.0 4.3 15.6 1.0 4.6 4.6 0.8 20.4 6.7 6.8 1.8 9.8 0.4 3.3 3.7 0.5 13.5 10.3 0.0 3.7 1.5 16.9 0.9 0.0 29.0 1.3 0.0 0.0 45.4 5.3 0.9 12.0 2.5 6.8 0.0 33.2 5.6 72.9 31.7 24.1 20.6 77.4 0.0 8.0 0.0 0.2 4.3 12.7 2.2 13.8 5.9 NTPCR "C1orf57, HCR-NTPase, MGC13186" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol NA NA Cytosol "HPA028125: AB_10601091, HPA054304: AB_2682443" "unprognostic (2.67e-1)" "unprognostic (2.28e-2)" "unprognostic (1.63e-2)" "unprognostic (7.59e-2)" "unprognostic (5.85e-3)" "unprognostic (1.04e-1)" "unprognostic (8.70e-3)" "unprognostic (2.12e-1)" "unprognostic (6.00e-2)" "unprognostic (5.03e-3)" "unprognostic (4.78e-2)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (6.37e-3)" 5.4 9.8 13.2 5.8 14.9 2.5 8.7 14.5 15.9 9.9 8.0 11.1 4.1 5.1 9.6 9.5 8.0 11.3 9.6 10.3 13.3 13.1 8.4 6.1 7.4 6.5 13.7 10.8 12.9 13.4 16.9 8.0 6.3 18.5 8.8 10.3 10.8 10.1 10.0 26.8 9.9 6.8 9.9 12.6 6.3 5.8 11.2 11.0 5.7 13.6 11.1 6.5 7.1 7.4 2.4 1.5 3.3 1.8 1.6 4.3 1.3 2.5 6.2 7.1 3.5 5.3 7.0 0.1 1.7 5.5 5.3 7.2 4.4 3.0 3.9 3.8 3.4 3.0 3.4 4.7 6.3 5.8 2.9 8.9 1.2 3.9 5.6 5.5 2.1 2.4 9.3 12.3 5.1 5.2 5.3 4.3 7.5 3.4 6.1 6.2 1.8 5.5 5.6 7.0 5.1 7.4 3.6 4.6 5.7 7.8 3.1 6.2 10.3 2.4 2.1 2.5 5.6 5.2 4.8 3.2 4.4 3.6 4.8 4.7 6.9 5.6 4.5 5.2 5.2 6.3 1.1 1.6 0.8 2.1 1.8 2.5 1.6 3.0 1.3 1.5 2.4 4.3 3.5 3.3 1.6 1.6 0.6 3.5 1.3 13.2 14.9 14.5 15.9 13.3 13.1 13.7 10.8 18.5 11.0 17.9 19.7 13.4 32.1 17.2 15.2 58.9 28.1 12.0 11.4 24.4 25.5 55.1 79.6 53.6 28.3 24.0 38.0 0.0 56.9 49.7 26.7 31.6 16.1 32.1 37.9 9.5 24.8 26.4 19.2 21.4 18.7 22.0 21.9 33.3 46.4 34.1 37.9 21.0 28.7 60.8 20.0 12.9 24.7 60.2 34.9 20.8 23.5 17.5 61.5 31.6 NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242222-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 59.5" "Cell type enhanced" "Detected in many" 7 "Erythroid cells: 233.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol No No Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" 8.8 3.9 7.4 12.6 13.4 37.1 10.8 5.0 10.8 5.9 9.0 8.7 2.2 9.1 8.2 9.2 13.1 6.0 8.1 11.3 8.7 4.7 4.1 2.9 7.2 18.9 8.2 7.0 4.8 4.0 0.7 1.8 5.8 7.2 7.2 6.3 4.0 5.5 4.2 12.0 18.8 9.3 10.5 11.9 11.1 5.5 26.7 5.3 30.7 4.1 14.4 17.2 6.8 8.1 18.3 59.5 11.9 21.3 10.1 20.4 13.0 21.7 35.1 19.3 25.5 7.1 9.8 14.2 9.6 8.4 13.2 15.4 18.9 16.5 23.0 7.8 10.5 26.9 26.6 14.6 14.6 7.7 10.2 25.0 17.9 29.6 16.0 1.7 13.9 18.1 6.4 3.8 19.0 6.8 4.3 7.1 33.5 14.2 25.7 14.7 55.5 25.9 54.2 41.4 10.8 21.7 36.3 28.6 19.2 7.2 12.3 19.4 26.9 9.9 29.2 4.4 14.6 19.2 37.0 6.5 12.7 48.5 29.3 22.8 19.9 15.0 23.8 12.8 34.7 45.6 9.0 17.5 11.9 12.9 21.3 10.2 18.3 15.1 13.6 26.6 18.0 15.1 13.1 4.6 10.1 17.4 59.5 20.4 13.0 7.4 13.4 5.0 10.8 8.7 4.7 8.2 7.0 7.2 5.3 6.0 6.9 41.2 21.9 35.6 10.2 15.1 12.7 8.1 7.9 10.4 3.9 30.9 16.6 20.1 42.6 10.8 14.4 233.6 32.2 67.3 28.8 13.6 61.0 5.3 76.9 0.0 7.5 4.3 37.3 78.4 20.4 69.4 43.9 36.9 26.8 18.6 17.6 17.3 17.7 11.7 6.1 32.3 28.5 80.4 63.8 32.4 19.8 39.2 33.8 16.0 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 28.8;seminal vesicle: 36.3;testis: 27.2" "Group enriched" "Detected in some" 5 "Ito cells: 54.6;Peritubular cells: 27.3" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 6.2;HAP1: 11.6;HEK 293: 8.6;NTERA-2: 21.3;SH-SY5Y: 4.6;SuSa: 4.4;U-2 OS: 10.7" "HPA047027, HPA057684" Approved Approved Cytosol NA NA Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 1.0 2.3 9.3 1.4 10.7 1.8 1.4 6.0 13.1 4.4 2.0 0.9 28.8 1.1 5.5 18.3 1.7 3.4 2.0 0.9 4.9 13.6 3.1 1.9 0.7 0.9 5.3 8.0 19.2 0.6 0.5 4.5 0.5 6.2 17.9 1.3 0.8 1.0 36.3 0.5 1.0 1.2 4.9 1.9 3.1 1.1 27.2 1.2 0.0 0.8 0.0 0.9 2.8 2.9 0.8 0.1 0.0 0.7 2.1 1.0 0.3 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 11.6 0.5 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 21.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.8 1.0 0.0 0.1 0.3 0.0 0.6 0.0 2.1 0.5 0.0 0.0 0.3 9.3 10.7 6.0 11.7 4.9 13.6 5.3 8.0 6.2 1.2 0.0 2.2 0.0 4.6 0.9 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.4 0.4 2.1 0.0 0.0 0.2 0.0 0.0 54.6 3.4 4.0 5.5 0.0 1.7 0.0 0.0 1.8 0.0 0.0 27.3 0.0 0.4 0.0 1.9 2.4 7.9 0.1 0.3 0.0 0.0 0.0 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496596 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;testis: 35.5" "Cell type enhanced" "Detected in many" 7 "Basal keratinocytes: 13.6;Peritubular cells: 19.4;Smooth muscle cells: 12.7;Spermatocytes: 13.4;Spermatogonia: 11.9" "Cancer enhanced" "Detected in many" "testis cancer: 17.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.7;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD8 T-cell: 3.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 3.7" "Cell line enhanced" "Detected in many" "HAP1: 33.6;NTERA-2: 21.0" "HPA047027, HPA057684" Approved Approved Cytosol NA NA Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.2 5.4 11.2 1.4 21.9 1.6 2.8 7.4 26.1 3.8 2.6 0.8 4.4 1.7 5.9 4.3 1.9 1.6 2.2 0.8 7.0 17.9 0.9 0.6 0.8 1.1 5.3 12.7 10.0 3.8 0.5 2.8 0.6 5.3 10.1 1.4 0.5 1.3 11.9 0.6 1.7 1.5 5.0 1.8 0.9 0.9 35.5 1.1 3.6 1.0 0.2 1.1 1.7 1.6 0.5 0.4 0.0 0.2 1.9 3.7 1.0 0.0 0.5 10.1 0.0 8.8 11.2 0.0 4.7 1.3 0.2 0.2 0.0 0.0 0.0 0.2 5.7 5.6 0.7 33.6 11.5 0.1 0.0 2.2 0.0 0.0 0.0 4.1 0.0 2.2 6.8 4.6 3.0 11.1 1.9 7.9 10.4 0.0 0.0 9.5 0.2 12.7 0.0 21.0 0.0 8.5 0.0 7.1 0.0 2.1 0.0 0.0 6.6 2.0 0.0 1.8 5.2 0.0 0.0 4.6 2.4 11.1 0.7 0.0 4.4 2.0 7.2 1.5 0.0 0.9 0.0 0.0 0.0 3.7 0.0 1.4 0.5 1.2 1.9 0.4 0.3 0.2 3.1 0.0 1.9 0.2 0.2 0.0 1.0 11.2 21.9 7.4 14.9 7.0 17.9 5.3 12.7 5.3 1.1 0.0 0.0 0.0 4.8 13.6 1.5 0.4 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.2 9.4 0.0 0.0 0.0 1.3 0.9 4.1 9.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 10.2 8.1 0.6 5.0 0.0 0.0 0.9 2.2 0.0 19.4 0.0 0.1 0.0 12.7 13.4 11.9 8.0 0.2 0.0 0.0 1.1 NUDT12 DKFZP761I172 ENSG00000112874 "Nudix hydrolase 12" Q9BQG2 5 103548855-103562793 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Distal tubular cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045449 Supported NA NA "HPA045449: AB_2679327" "unprognostic (1.94e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.44e-1)" "unprognostic (7.53e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "unprognostic (8.79e-2)" "unprognostic (9.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.92e-1)" "prognostic favorable (2.86e-5)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (2.67e-1)" "unprognostic (5.92e-2)" 6.3 15.2 10.1 3.5 13.3 0.9 11.4 6.1 12.5 9.2 11.9 10.2 10.9 15.3 6.1 11.7 10.1 8.1 7.7 9.2 10.0 8.9 24.7 25.3 6.1 2.4 13.1 8.5 6.6 15.3 26.9 14.7 6.8 13.7 13.9 13.4 8.4 11.2 7.9 12.1 8.2 15.8 8.7 14.8 4.3 12.5 5.9 14.8 5.0 15.0 8.7 3.4 8.9 6.0 1.5 3.9 0.0 1.3 1.5 2.2 0.9 4.0 1.8 10.1 3.8 6.9 14.5 0.0 7.2 6.9 6.6 8.5 3.5 14.9 0.0 4.8 4.1 7.3 6.7 9.4 15.0 9.2 0.0 5.7 4.2 7.1 1.8 7.1 0.0 0.0 6.9 13.2 4.4 11.4 7.7 4.4 0.0 6.8 0.0 11.4 7.5 0.3 0.2 5.1 0.0 5.7 0.0 8.9 3.3 11.1 7.1 7.6 7.9 4.7 7.0 11.0 8.3 15.4 4.2 5.4 8.3 3.0 7.2 5.7 4.9 7.5 0.0 8.5 0.0 6.0 0.0 0.9 0.0 0.0 1.3 0.0 0.9 0.8 0.5 2.8 1.5 2.2 1.0 0.0 1.5 0.9 3.9 0.6 0.9 10.1 13.3 6.1 12.5 10.0 8.9 13.1 8.5 13.7 14.8 8.9 7.0 2.4 5.1 3.0 9.0 11.2 15.3 14.7 4.5 12.2 2.0 4.9 49.7 8.9 4.2 2.9 16.5 0.0 12.2 3.1 3.4 8.4 1.1 12.9 5.2 11.1 4.1 1.8 4.1 3.4 12.4 4.3 8.5 2.8 14.0 12.9 10.2 12.4 9.9 27.0 14.6 6.5 5.8 11.1 4.4 2.8 2.5 0.0 11.6 7.0 NUDT14 UGPP ENSG00000183828 "Nudix hydrolase 14" O95848 14 105172938-105181323 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046755, HPA058759" Approved Approved Nucleoli,Microtubules NA NA Microtubules Nucleoli "HPA046755: AB_10963433, HPA058759: AB_2683809" "unprognostic (1.05e-2)" "unprognostic (6.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.55e-1)" "unprognostic (1.05e-3)" "unprognostic (9.17e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.16e-3)" "unprognostic (3.13e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (7.21e-3)" "unprognostic (2.38e-1)" 18.2 12.6 22.4 5.0 16.0 3.1 14.3 2.5 23.4 6.5 11.0 7.9 5.9 16.7 4.7 11.7 7.1 12.6 9.8 20.9 15.4 13.5 16.7 11.2 12.6 9.4 16.1 14.8 4.0 26.0 4.7 27.6 4.8 11.2 10.5 4.6 14.7 16.7 9.9 28.7 6.2 13.8 3.1 13.2 6.3 12.7 8.9 7.8 3.1 17.9 9.2 5.7 4.9 4.7 5.8 15.1 1.7 27.3 6.1 5.8 8.9 8.2 11.3 1.0 4.4 1.3 1.6 18.1 2.3 3.1 3.8 5.5 8.0 8.8 0.6 11.6 1.2 8.5 10.4 0.5 6.3 0.3 4.3 8.3 1.8 4.9 5.5 9.7 2.2 22.3 2.3 8.0 0.9 0.7 1.6 7.5 4.1 2.8 1.4 1.3 24.0 0.2 0.0 5.9 19.5 15.8 4.3 10.4 4.8 4.1 23.8 15.7 2.3 4.1 0.1 9.6 1.9 8.9 10.7 17.6 6.3 2.8 4.5 2.3 0.7 0.4 1.0 9.3 2.5 2.3 1.7 18.5 0.5 5.8 17.4 3.6 5.8 4.6 3.8 15.1 4.0 4.5 5.2 0.6 6.1 27.3 7.3 2.5 8.9 22.4 16.0 2.5 23.4 15.4 13.5 16.1 14.8 11.2 7.8 11.9 22.0 13.7 80.0 34.6 11.8 47.7 35.7 34.8 5.7 33.2 17.7 39.7 149.2 84.7 2.5 43.4 95.9 0.0 26.5 19.7 19.5 39.7 39.1 21.8 112.1 33.4 35.8 22.7 24.1 8.2 10.6 28.5 43.9 36.9 61.8 28.1 58.1 126.7 3.5 138.7 12.3 0.0 9.5 10.0 28.9 16.7 31.9 15.2 80.1 65.1 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037567-48047222 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Extravillous trophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No Nucleoplasm "HPA038968: AB_10697402, HPA038969: AB_2676295" "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavorable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 15.0 15.2 11.4 16.6 14.6 16.5 18.0 14.1 17.7 14.8 21.1 9.5 14.3 22.1 11.1 15.5 23.8 12.8 13.5 13.3 10.5 15.7 20.3 21.3 11.1 7.4 12.8 11.1 13.0 13.8 6.1 18.6 14.2 15.8 16.9 24.1 8.2 14.1 12.6 15.9 10.8 20.5 11.3 11.9 9.6 13.9 22.2 10.6 11.6 22.3 24.1 12.0 12.1 14.2 4.7 7.0 4.6 9.9 3.8 9.2 4.1 19.6 11.9 22.4 9.9 9.2 13.4 16.5 16.0 15.1 17.7 17.2 17.6 19.1 14.6 9.1 12.6 15.9 23.2 21.7 23.5 27.4 7.6 18.7 14.2 11.7 19.1 8.6 21.2 13.6 9.2 15.1 14.3 20.2 8.0 19.1 14.7 12.5 5.8 28.4 9.6 16.7 20.1 35.9 30.1 14.2 11.5 14.5 9.5 19.7 15.0 13.6 14.5 10.9 18.8 12.4 20.1 9.6 16.1 9.8 12.5 15.2 15.6 22.0 3.1 5.1 18.3 6.5 16.7 20.1 2.1 7.3 4.6 4.6 9.9 4.5 4.7 7.4 5.8 7.0 4.7 8.8 9.2 1.6 3.8 6.7 5.6 5.0 4.1 11.4 14.6 14.1 17.7 10.5 15.7 12.8 11.1 15.8 10.6 11.9 11.2 7.5 29.2 14.7 7.3 10.8 15.3 12.0 20.5 7.0 2.0 29.2 41.4 15.1 13.5 11.7 22.0 0.0 15.4 67.2 13.0 26.5 9.2 14.7 14.6 36.5 8.1 8.0 6.7 7.2 15.5 9.6 10.1 10.8 19.4 7.7 12.6 11.5 11.7 33.4 7.1 0.0 21.2 5.8 30.2 17.9 31.8 5.7 29.5 30.3 NUDT16 FLJ31265 ENSG00000198585 "Nudix hydrolase 16" Q96DE0 3 131381671-131388830 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Kupffer cells: 138.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 18.2;eosinophil: 18.8;intermediate monocyte: 21.9;myeloid DC: 13.6;neutrophil: 14.6;non-classical monocyte: 24.5" "Group enriched" "Detected in all" 4 "dendritic cells: 13.6;granulocytes: 18.8;monocytes: 24.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060452, HPA062492" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA060452: AB_2684279, HPA062492: AB_2684781" "unprognostic (4.85e-3)" "prognostic favorable (9.39e-5)" "unprognostic (3.19e-3)" "unprognostic (9.21e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-2)" "unprognostic (9.96e-2)" "unprognostic (1.15e-1)" "unprognostic (5.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.77e-1)" "unprognostic (5.88e-2)" "prognostic favorable (1.05e-7)" "unprognostic (3.29e-1)" "unprognostic (1.62e-1)" "unprognostic (2.00e-2)" "unprognostic (9.44e-2)" 25.9 13.4 22.1 13.1 22.0 8.7 13.1 13.5 20.5 11.1 32.8 23.9 13.9 20.2 11.7 11.6 8.7 14.0 13.6 22.2 21.1 19.6 25.9 23.1 16.2 31.1 27.7 16.9 23.0 18.3 32.9 9.7 7.6 20.1 13.4 18.4 13.6 11.7 13.6 20.3 6.8 37.5 18.5 30.4 22.2 13.8 9.5 21.6 2.2 17.1 11.5 9.1 12.4 8.4 4.3 13.6 18.8 24.5 3.7 4.3 6.7 12.6 6.8 11.2 5.8 22.5 20.5 5.2 10.4 9.6 7.0 7.3 10.4 5.7 2.1 9.1 9.6 13.9 9.3 9.9 6.5 11.2 6.3 7.2 5.4 8.7 10.0 14.4 9.0 9.9 18.2 5.8 4.6 12.7 6.3 10.9 0.0 6.1 11.0 6.8 13.2 0.0 2.4 8.7 12.7 10.1 7.1 8.1 16.0 7.0 10.3 5.5 9.6 6.2 6.3 9.5 9.9 13.8 7.2 10.7 11.5 5.0 21.0 8.0 11.0 10.8 0.3 7.4 7.0 6.3 2.2 18.2 18.8 2.6 21.9 2.7 4.3 2.7 2.4 13.6 4.2 2.4 2.4 14.6 3.7 24.5 1.8 4.3 6.7 22.1 22.0 13.5 20.5 21.1 19.6 27.7 16.9 20.1 21.6 14.9 31.3 19.1 10.7 7.4 22.7 83.1 40.8 16.0 18.2 19.2 7.9 18.7 58.0 20.4 59.4 30.8 62.9 23.3 32.8 21.8 21.4 14.7 18.5 95.7 54.0 41.3 24.3 84.1 138.2 27.2 24.5 46.3 16.9 14.4 61.2 10.0 23.8 50.3 37.1 92.4 18.3 25.8 23.7 17.6 5.1 4.6 6.1 20.8 42.4 14.7 NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106872-22109419 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "HPA028581: AB_10601381, HPA030125: AB_2673324" "unprognostic (9.90e-3)" "prognostic favorable (1.43e-4)" "unprognostic (4.88e-3)" "prognostic favorable (2.49e-6)" "unprognostic (1.29e-2)" "unprognostic (6.82e-3)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (5.30e-2)" "unprognostic (1.67e-1)" "prognostic favorable (2.47e-4)" "unprognostic (1.43e-1)" "prognostic favorable (8.30e-4)" "unprognostic (3.59e-3)" "unprognostic (1.05e-1)" "unprognostic (6.84e-2)" "unprognostic (2.32e-1)" 3.6 2.7 2.9 4.4 6.4 2.9 3.6 5.3 6.8 2.0 6.1 4.3 5.4 5.3 1.6 11.9 3.7 4.3 3.8 2.5 1.7 2.9 2.9 4.5 6.3 3.2 3.3 1.2 8.6 2.1 5.2 1.8 3.7 3.6 3.8 3.8 5.6 11.0 1.0 3.6 5.4 2.7 2.5 6.0 5.6 2.8 3.4 7.1 5.0 2.3 5.8 3.2 0.0 3.6 3.6 5.0 3.2 7.8 4.7 1.5 6.8 14.5 0.5 3.2 11.5 4.3 8.0 4.0 11.1 5.5 6.2 3.4 5.4 5.1 6.6 4.9 13.8 12.0 2.1 6.7 1.8 6.3 2.0 4.3 4.1 3.3 7.6 1.3 13.5 7.9 6.4 2.2 5.7 7.1 6.9 11.3 3.1 8.6 5.1 7.2 5.7 3.9 0.8 4.2 3.5 2.6 1.3 5.5 7.9 6.0 1.6 2.4 2.9 3.5 3.5 3.6 8.2 7.2 5.5 3.5 1.9 4.7 2.1 3.8 0.4 1.6 6.2 3.9 8.6 0.1 2.9 5.0 4.7 3.2 4.3 2.6 3.7 2.7 2.0 3.6 4.0 2.2 0.7 7.8 2.3 3.6 1.4 1.5 3.0 2.1 5.2 3.9 1.8 3.0 1.6 12.7 2.7 1.2 5.2 0.0 5.5 5.0 6.8 10.6 3.0 15.0 0.0 11.8 8.3 3.9 3.7 0.0 2.5 12.8 3.2 2.9 4.9 19.5 10.0 2.8 3.0 5.0 12.6 7.0 3.7 8.6 11.5 3.2 8.8 1.3 0.0 2.8 2.6 2.0 1.6 2.6 8.5 6.3 2.2 NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343713 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "CAB004684: AB_425306, HPA044903: AB_2679139, HPA058623: AB_2683780, HPA067639: AB_2685877" "unprognostic (2.74e-3)" "unprognostic (2.58e-2)" "unprognostic (3.37e-1)" "unprognostic (2.05e-3)" "unprognostic (3.08e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (6.55e-2)" "unprognostic (7.06e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (2.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" 12.0 18.0 21.6 9.6 21.9 10.2 20.6 14.0 25.5 14.9 14.9 26.0 15.4 12.8 15.7 30.2 14.5 20.5 12.3 16.0 17.3 18.6 10.7 17.5 11.2 12.2 19.5 19.0 28.3 20.9 12.0 19.0 14.1 20.5 16.5 15.3 15.7 16.1 13.0 30.8 13.9 10.1 14.7 20.7 11.3 13.0 8.6 19.1 18.6 3.8 13.2 13.8 14.4 12.1 16.6 15.8 14.3 12.2 14.3 22.2 11.2 23.8 9.8 12.8 4.5 8.8 16.3 9.2 11.5 26.1 13.3 14.0 6.7 11.3 6.6 9.6 14.3 5.1 10.5 11.5 28.4 13.6 24.8 10.3 14.3 18.5 12.6 25.6 11.0 5.9 16.5 18.4 17.2 32.4 18.2 27.5 23.2 4.0 27.1 19.5 14.8 11.4 10.3 7.9 10.6 28.3 14.8 8.0 16.7 13.1 7.8 2.6 10.4 18.7 7.1 10.8 12.0 5.7 11.9 17.7 11.5 10.4 7.5 11.9 6.1 9.9 11.7 14.4 10.6 14.3 14.3 12.2 9.7 11.7 10.3 16.7 16.6 19.2 15.2 15.8 15.0 22.2 19.6 4.5 14.3 10.7 14.7 19.7 11.2 21.6 21.9 14.0 25.5 17.3 18.6 19.5 19.0 20.5 19.1 3.0 5.5 15.9 17.8 25.0 13.1 18.6 43.3 17.4 11.4 15.7 5.9 33.9 74.6 22.6 9.7 21.5 18.6 0.0 34.7 35.6 23.1 17.1 12.7 31.0 32.5 7.9 21.4 30.1 38.4 21.8 25.3 23.9 21.9 32.5 29.1 16.2 26.1 26.9 18.0 39.6 12.8 25.8 23.6 35.8 17.5 27.6 15.8 25.3 31.4 15.7 NUDT22 MGC13045 ENSG00000149761 "Nudix hydrolase 22" Q9BRQ3 11 64225941-64230686 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039334, HPA053464" Approved Enhanced Nucleoplasm No No Nucleoplasm "HPA039334: AB_10795174, HPA053464: AB_2682160" "unprognostic (2.72e-1)" "unprognostic (3.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (9.75e-2)" "unprognostic (1.73e-3)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-1)" "unprognostic (7.65e-2)" "unprognostic (6.61e-2)" "prognostic favorable (2.18e-6)" "unprognostic (1.76e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (8.54e-2)" 9.2 16.8 8.1 16.0 9.2 14.3 9.8 7.3 12.8 9.2 24.2 9.1 30.9 29.6 9.1 16.9 17.8 9.0 16.7 23.4 8.3 7.0 21.1 30.1 10.2 15.9 10.5 8.4 7.9 26.4 13.8 12.2 14.7 8.6 12.3 8.5 9.0 28.6 35.2 24.9 12.9 23.7 11.4 7.8 20.5 18.5 7.8 7.7 19.5 15.4 15.7 19.6 13.5 9.4 30.0 49.1 20.0 33.9 19.2 25.0 20.1 14.7 9.4 2.4 9.9 3.6 4.4 9.0 6.2 6.5 4.5 4.2 6.1 12.6 7.0 16.5 6.2 6.8 15.5 1.4 9.9 0.6 9.0 4.0 9.4 6.9 6.3 10.8 6.0 15.7 6.8 7.4 4.8 5.1 3.4 7.3 8.4 4.6 7.7 5.3 22.1 8.4 11.2 3.7 9.1 19.9 10.4 4.0 26.0 7.8 8.2 5.5 8.8 5.5 20.9 24.8 0.9 21.3 6.9 6.7 7.6 7.2 23.8 5.3 28.9 11.4 4.4 26.1 7.1 8.8 13.8 28.7 20.0 23.0 33.9 20.5 25.3 20.3 22.4 29.1 30.0 18.0 19.6 17.3 19.2 31.8 49.1 25.0 20.1 8.1 9.2 7.3 12.8 8.3 7.0 10.5 8.4 8.6 7.7 3.0 13.4 41.3 23.3 10.6 12.3 3.1 61.1 4.0 6.8 38.4 11.8 92.1 139.3 53.1 12.7 17.7 92.0 0.0 76.6 42.4 24.2 26.6 14.0 47.8 50.9 28.6 35.7 27.0 50.0 6.5 18.7 38.1 32.1 73.9 66.5 25.6 56.4 92.1 18.4 113.9 16.8 12.9 20.6 4.9 8.3 15.3 56.4 39.2 56.2 28.8 NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392674 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol NA NA 110000 Cytosol "HPA047027: AB_2679907, HPA055953: AB_2682984" "unprognostic (2.42e-1)" "prognostic favorable (5.29e-4)" "unprognostic (9.63e-3)" "unprognostic (4.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-3)" "unprognostic (4.21e-2)" "unprognostic (4.93e-3)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" "unprognostic (4.63e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.24e-2)" 10.5 11.4 38.8 9.3 28.6 8.8 12.6 33.4 40.0 15.4 11.4 16.8 10.3 7.7 11.4 25.9 10.8 15.2 8.5 16.9 33.8 30.0 15.3 10.1 11.2 10.5 29.4 25.6 17.4 9.1 27.9 9.3 8.9 26.1 11.4 9.7 11.2 9.4 15.6 50.7 11.2 8.0 11.2 20.3 13.0 8.4 7.3 21.3 5.4 21.3 8.7 12.1 8.6 9.9 4.5 6.4 12.4 5.9 2.1 3.9 2.6 5.4 4.0 10.8 21.1 7.2 12.2 4.7 4.0 6.7 4.1 3.0 4.8 3.8 19.6 5.4 7.1 2.7 4.6 6.1 10.8 7.7 7.3 7.8 21.6 5.6 10.4 7.2 20.3 11.3 11.0 10.0 5.0 9.4 5.3 11.8 10.2 21.4 7.1 6.6 5.7 14.0 23.8 6.9 16.1 4.0 12.3 8.9 20.4 9.4 11.4 15.2 17.0 8.8 12.5 15.9 3.4 12.5 14.6 12.9 8.3 3.0 7.2 8.6 6.1 14.1 14.4 5.0 20.8 12.9 1.9 5.8 12.4 3.4 5.9 3.9 3.4 3.4 3.2 6.4 4.5 3.2 3.7 4.1 2.1 5.8 3.2 2.4 2.6 38.8 28.6 33.4 40.0 33.8 30.0 29.4 25.6 26.1 21.3 14.9 22.4 43.5 59.4 53.1 115.6 43.3 63.7 46.8 14.8 40.1 111.9 28.0 11.6 15.4 3.0 55.9 18.4 0.0 24.5 26.3 42.3 39.4 12.8 52.1 67.2 160.5 47.2 84.7 91.0 4.0 34.8 58.5 50.6 22.6 24.7 115.6 20.8 19.8 59.4 19.2 125.0 58.2 46.4 44.7 78.0 52.7 16.4 20.1 25.2 59.3 NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.7" "Cell type enhanced" "Detected in all" 5 "Muller glia cells: 411.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol NA NA Cytosol "HPA017593: AB_1854703, HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (1.44e-2)" "unprognostic (2.15e-1)" "unprognostic (4.40e-3)" "unprognostic (4.25e-1)" "unprognostic (3.08e-3)" "unprognostic (1.42e-1)" "unprognostic (8.12e-2)" "unprognostic (9.09e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (5.01e-1)" "unprognostic (8.32e-3)" 17.2 29.7 14.1 14.7 9.5 37.4 20.4 7.0 29.0 15.2 14.7 6.7 17.5 6.5 13.6 24.8 13.7 12.8 40.0 140.7 12.4 12.4 47.9 11.2 11.3 10.9 9.4 13.7 41.9 21.1 16.1 11.9 19.2 13.9 27.1 16.9 25.1 65.2 14.8 40.3 8.1 12.7 13.8 12.6 9.2 13.1 10.6 6.3 14.6 25.5 22.4 8.9 19.6 32.9 6.0 4.1 13.6 3.6 7.6 6.6 2.5 5.8 5.0 9.1 10.2 34.0 14.1 11.5 16.3 13.0 9.4 6.9 46.9 14.6 8.2 3.6 13.0 6.1 7.4 25.5 8.2 14.4 12.5 5.4 30.7 4.4 23.9 32.7 15.9 7.4 30.5 27.5 9.6 21.6 47.1 53.1 14.8 31.1 11.5 10.7 6.0 14.8 15.2 14.4 14.4 12.0 12.4 8.2 8.8 11.2 42.3 7.4 9.5 13.2 25.9 36.5 15.3 18.8 20.8 20.1 8.0 4.7 12.0 10.3 6.5 8.1 12.1 4.2 12.6 24.4 8.2 2.8 13.6 3.9 3.6 6.6 6.0 5.8 3.9 2.6 4.7 6.2 5.8 2.4 7.6 2.9 4.1 5.2 2.5 14.1 9.5 7.0 29.0 12.4 12.4 9.4 13.7 13.9 6.3 17.9 42.6 40.8 110.6 103.7 39.3 226.3 94.3 91.0 31.8 59.3 58.9 156.3 306.7 20.9 78.9 50.0 102.5 327.1 14.7 23.0 86.0 142.6 25.3 48.9 37.7 39.7 146.0 28.8 34.5 17.0 36.2 31.8 101.3 12.6 83.5 411.5 37.2 85.6 43.9 43.1 40.3 71.1 166.9 28.7 7.7 84.6 137.0 29.9 64.3 133.5 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165325-12196144 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA 660000 Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavorable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 19.6 22.0 17.4 18.6 21.2 13.5 20.2 15.4 21.4 16.7 20.4 16.1 15.2 17.3 10.0 16.5 25.8 16.3 12.1 10.0 16.2 14.3 26.0 57.1 16.8 22.7 21.7 12.8 12.5 16.9 19.1 35.7 19.9 18.5 13.4 24.2 13.2 16.7 19.7 5.1 20.6 15.9 11.6 17.9 22.4 14.1 8.0 21.5 28.2 19.1 16.5 29.5 16.2 18.6 22.4 45.9 50.1 19.5 16.2 37.0 20.4 35.6 26.3 31.5 29.3 30.5 30.2 27.9 26.4 16.9 31.1 33.4 37.7 34.1 35.7 23.0 21.4 19.5 35.9 43.9 40.9 28.7 29.2 42.9 29.7 32.3 55.4 31.8 19.7 20.9 31.7 24.5 33.9 17.3 24.1 39.7 57.2 39.7 24.4 28.3 32.7 36.8 23.1 27.4 57.3 16.4 33.7 11.4 41.4 29.1 12.3 15.2 22.8 32.0 24.7 36.7 38.5 42.3 20.3 24.8 13.3 25.5 37.0 32.3 20.6 36.2 48.0 27.9 25.7 9.8 8.1 19.1 33.5 22.8 19.5 26.2 22.4 24.6 26.8 27.0 18.3 17.0 23.0 50.1 16.2 14.8 45.9 37.0 20.4 17.4 21.2 15.4 21.4 16.2 14.3 21.7 12.8 18.5 21.5 23.8 37.8 33.5 51.1 38.1 19.2 2.8 25.5 60.2 39.8 22.7 15.7 73.5 63.0 74.1 27.1 31.4 34.2 23.3 72.2 127.8 35.8 30.5 31.1 116.5 105.0 20.6 36.8 40.5 41.3 6.6 36.5 39.3 28.7 110.0 34.5 32.9 64.5 28.1 27.3 95.7 22.5 32.3 25.6 20.2 27.5 52.9 48.6 51.7 51.0 40.6 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422582-87459454 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" NA NA 9000 "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favorable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favorable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 14.2 25.6 19.5 10.0 22.7 4.0 31.1 22.5 22.3 17.9 19.6 11.8 18.0 27.0 17.3 24.5 12.8 16.2 11.4 18.0 21.8 19.4 28.1 30.9 15.8 12.2 22.9 16.5 18.4 64.1 35.4 33.1 17.5 20.0 22.5 18.3 11.3 20.2 18.7 23.8 10.2 30.0 16.0 17.0 9.9 14.1 14.1 22.6 7.6 22.7 16.0 9.7 13.6 35.9 13.9 13.8 3.7 13.9 9.3 18.3 10.6 10.6 11.6 12.9 6.5 25.6 16.2 10.4 20.7 13.5 8.0 8.0 8.1 18.5 15.7 21.2 16.7 14.6 7.4 11.9 14.5 12.8 11.7 9.1 5.1 13.5 14.3 16.1 9.4 8.5 15.5 19.3 9.5 9.0 16.5 15.9 5.1 14.4 10.6 15.0 14.1 13.1 10.2 10.4 25.1 4.7 15.4 11.5 9.2 60.2 9.9 15.7 10.7 13.3 23.6 10.5 17.5 13.5 13.6 16.3 12.9 12.5 9.4 10.1 8.1 6.3 12.8 18.5 8.9 16.3 0.9 11.7 3.7 13.4 13.8 12.4 13.9 13.4 13.2 13.8 12.0 15.9 18.3 1.3 9.3 13.9 13.0 12.3 10.6 19.5 22.7 22.5 22.3 21.8 19.4 22.9 16.5 20.0 22.6 62.5 31.4 15.2 36.7 8.9 13.8 35.3 43.3 45.5 60.3 22.7 25.5 27.4 34.9 42.5 19.0 27.0 24.4 0.0 31.7 28.2 26.6 34.7 19.7 42.0 28.9 6.4 16.1 17.8 11.6 7.6 23.6 17.1 10.1 22.6 15.4 21.8 28.5 25.8 25.1 47.3 15.3 25.8 26.7 29.8 21.7 8.3 31.5 7.2 22.2 26.3 OCRL OCRL1 ENSG00000122126 "OCRL, inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" Hydrolase "Cataract, Ciliopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Peritubular cells: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;monocytes: 6.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012495 Approved Approved "Microtubules,Centriolar satellite,Cytosol" NA NA Cytosol "Microtubules, Centriolar satellite" "HPA012495: AB_1851804" "prognostic unfavorable (2.93e-5)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (6.34e-3)" "unprognostic (9.88e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-2)" "unprognostic (2.68e-1)" "unprognostic (3.08e-3)" "unprognostic (2.56e-2)" "unprognostic (6.30e-3)" "unprognostic (1.74e-1)" "unprognostic (4.61e-3)" "unprognostic (4.10e-1)" "unprognostic (5.83e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" 12.1 20.5 10.7 6.0 18.2 5.3 10.8 13.4 23.1 12.7 13.4 10.1 28.8 9.1 15.8 19.7 13.3 12.8 13.8 8.6 13.0 20.5 10.9 11.3 8.6 6.0 12.9 15.1 33.0 12.4 37.3 20.3 13.2 17.8 21.7 14.1 15.3 8.5 27.7 11.4 9.6 9.8 21.5 8.0 6.3 11.4 23.2 6.4 4.3 19.0 5.6 4.1 18.0 9.2 0.4 2.4 0.3 6.6 0.0 0.7 0.7 9.7 11.2 9.3 10.5 16.4 13.7 9.1 14.9 11.9 15.5 14.4 7.5 7.1 0.8 25.7 12.6 18.2 6.1 17.1 11.4 16.1 0.0 11.5 3.0 10.1 7.5 12.2 3.0 0.3 11.4 15.0 15.2 15.1 15.4 11.5 4.5 4.0 7.4 16.0 12.7 2.2 4.2 3.3 12.9 16.7 2.2 9.6 5.8 8.8 10.1 11.3 14.3 7.1 10.1 7.8 12.4 7.2 5.3 9.6 12.6 5.8 13.1 14.8 2.1 1.6 2.0 8.9 11.1 9.9 0.0 2.1 0.0 0.2 2.4 0.7 0.3 0.1 0.1 2.4 0.4 0.6 0.2 0.3 0.0 6.6 0.9 0.1 0.7 10.7 18.2 13.4 23.1 13.0 20.5 12.9 15.1 17.8 6.4 3.0 8.5 0.8 3.1 4.1 9.9 7.9 5.1 4.0 10.3 17.4 5.9 5.1 3.3 4.9 19.5 5.3 13.7 0.0 3.1 4.7 5.1 5.7 0.0 10.9 4.3 12.7 16.8 7.4 10.4 5.9 21.3 4.4 8.5 2.8 11.7 8.6 6.7 10.7 32.2 3.9 6.0 0.0 5.7 6.4 14.0 6.5 4.8 0.0 9.7 6.0 OLAH "FLJ11106, SAST, THEDC1" ENSG00000152463 "Oleoyl-ACP hydrolase" Q9NV23 10 15032227-15073852 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "placenta: 61.3;testis: 24.0" "Cell type enriched" "Detected in some" 10 "Early spermatids: 347.4" "Group enriched" "Detected in some" 7 "testis cancer: 3.6;thyroid cancer: 0.8" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "neutrophil: 6.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.6" "Cell line enhanced" "Detected in some" "HSkMC: 5.8;hTCEpi: 7.4;LHCN-M2: 5.6;SK-BR-3: 8.8;SuSa: 4.8;U-266/70: 4.9" "HPA037947, HPA037948" Enhanced NA NA "HPA037947: AB_10795028, HPA037948: AB_10805352" "unprognostic (2.01e-1)" "unprognostic (6.12e-2)" "unprognostic (8.20e-3)" "unprognostic (4.04e-3)" "unprognostic (1.92e-1)" "unprognostic (8.09e-2)" "unprognostic (7.12e-2)" "unprognostic (5.12e-2)" "unprognostic (4.55e-1)" "unprognostic (3.74e-2)" "unprognostic (4.70e-1)" "unprognostic (1.69e-1)" "unprognostic (5.22e-10)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (5.11e-2)" "unprognostic (9.78e-2)" 1.0 1.1 0.2 0.2 0.7 1.2 5.2 0.3 0.7 0.8 0.5 0.3 0.1 0.0 0.2 0.4 2.7 1.4 1.1 0.8 0.2 0.2 0.8 0.4 1.9 4.3 0.9 0.1 0.2 0.1 0.1 1.5 61.3 0.4 0.1 0.0 0.3 3.0 0.1 0.5 0.4 0.3 0.1 0.5 8.0 0.2 24.0 0.3 0.2 1.2 0.1 0.3 0.3 1.1 0.5 1.1 6.6 0.4 1.0 0.6 0.1 0.2 0.6 0.7 0.5 0.3 1.1 2.2 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.0 0.0 0.6 0.2 0.0 0.2 0.7 0.4 0.2 0.3 0.4 0.0 0.9 0.0 0.6 5.8 7.4 0.9 0.1 0.1 0.7 0.2 0.5 0.3 5.6 0.0 0.5 0.7 0.7 0.2 0.4 0.7 1.3 1.8 0.0 0.0 0.0 0.4 0.3 8.8 0.1 4.8 0.2 0.5 1.0 0.1 2.9 1.3 0.1 4.9 1.6 0.4 2.7 0.5 0.0 1.4 0.4 0.4 0.4 0.2 0.3 0.2 0.6 0.2 0.2 0.5 0.3 0.3 6.6 1.0 0.2 1.1 0.4 0.1 0.2 0.7 0.3 0.3 0.2 0.2 0.9 0.1 0.4 0.3 3.0 1.1 0.0 0.2 0.2 0.0 0.3 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.9 347.4 0.0 0.0 0.0 0.0 1.4 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 35.4 4.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 7.8 0.0 0.7 6.5 0.4 1.7 1.7 0.3 9.5 0.5 0.0 0.1 OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1, mitochondrial dynamin like GTPase" O60313 3 193593144-193697823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Cardiomyocytes: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria NA NA 13000 "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: AB_2675388" "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favorable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" 17.0 19.7 18.2 13.5 31.7 25.9 15.9 20.2 30.9 13.9 21.8 11.1 12.6 20.0 15.2 11.8 18.8 11.8 12.8 43.9 23.0 19.4 21.8 24.1 10.7 15.3 19.0 22.4 13.2 13.4 20.9 15.6 13.8 28.0 15.5 20.5 9.1 15.7 20.8 38.4 14.6 17.3 16.5 17.0 13.1 16.7 7.6 10.8 18.0 16.8 18.4 14.2 16.5 13.6 8.3 8.8 8.2 17.6 5.0 7.5 5.9 26.0 8.4 8.5 9.3 7.5 11.9 9.0 12.7 11.7 13.9 13.6 20.3 8.8 17.3 27.4 11.9 12.7 17.0 14.8 14.3 24.7 20.8 12.0 29.9 7.5 10.2 11.7 24.6 13.8 13.3 12.8 13.4 19.1 8.6 11.7 7.3 12.7 17.0 13.8 20.6 9.5 13.7 11.9 15.0 28.0 12.5 18.7 18.5 10.4 16.3 18.5 11.3 18.9 21.2 13.4 6.8 27.8 19.5 11.7 12.9 9.8 13.8 26.6 15.4 17.8 33.9 14.3 19.7 12.9 8.2 8.1 7.7 7.2 9.3 6.6 8.3 6.8 6.8 8.8 6.3 6.9 7.3 3.2 5.0 17.6 4.6 7.5 5.9 18.2 31.7 20.2 30.9 23.0 19.4 19.0 22.4 28.0 10.8 14.9 20.0 20.6 13.8 14.2 17.0 130.0 15.3 16.0 20.5 17.4 29.5 16.2 14.9 14.8 7.2 13.5 20.6 70.0 20.7 12.2 15.9 15.5 18.5 30.2 15.9 20.6 22.4 16.0 23.5 10.2 14.7 21.2 20.3 11.8 20.6 15.7 22.7 7.0 13.8 26.9 21.6 6.5 17.5 11.3 15.0 19.6 15.0 12.8 25.8 19.6 OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.3" "Group enriched" "Detected in many" 4 "Early spermatids: 97.1;Late spermatids: 174.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.0;intermediate monocyte: 1.0;neutrophil: 3.8" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 3.0" "Cell line enhanced" "Detected in many" "AN3-CA: 22.7;BEWO: 14.2;Hep G2: 12.2;PC-3: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: AB_2681830" "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" 5.6 5.6 3.3 1.7 3.9 2.3 3.1 4.9 5.3 1.9 7.0 7.0 4.5 11.8 1.6 1.9 5.9 1.3 5.2 16.2 2.5 1.7 10.8 17.2 2.9 2.0 4.5 4.2 2.0 6.0 5.8 1.2 1.3 5.5 3.5 2.0 4.8 9.4 5.6 25.6 5.5 10.4 1.2 4.4 3.7 7.2 49.3 4.9 0.3 1.9 5.4 1.8 2.1 3.3 0.0 0.3 3.8 3.0 0.0 0.1 0.8 2.7 2.7 0.3 22.7 1.0 2.2 14.2 1.3 0.9 0.8 0.5 5.2 5.1 0.0 4.6 2.5 0.0 3.6 0.7 2.0 0.0 0.7 0.0 0.9 4.1 12.2 7.3 0.1 0.0 3.0 9.4 0.9 0.0 0.0 0.1 3.9 3.2 0.0 0.0 3.1 0.2 2.1 1.9 4.2 17.5 0.3 0.0 3.5 2.4 3.3 0.8 0.1 0.0 0.9 0.0 0.3 5.9 3.0 0.1 0.0 3.8 0.0 0.9 0.8 0.9 0.7 0.3 0.7 0.0 0.0 3.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.8 0.0 0.4 0.0 0.0 0.8 3.3 3.9 4.9 5.3 2.5 1.7 4.5 4.2 5.5 4.9 3.0 2.7 0.8 1.7 1.8 1.0 2.6 5.1 1.4 3.4 8.7 0.0 1.4 10.0 3.5 97.1 0.7 32.0 0.0 2.4 2.2 1.1 1.6 0.0 20.2 2.1 0.0 1.2 3.1 6.0 174.0 2.3 1.7 0.0 1.0 6.3 5.2 3.8 11.2 3.5 11.0 0.0 0.0 1.0 3.5 2.3 1.6 2.1 1.3 10.9 2.0 OTUB1 "FLJ20113, FLJ40710" ENSG00000167770 "OTU deubiquitinase, ubiquitin aldehyde binding 1" Q96FW1 11 63985853-64001811 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, DNA damage, DNA repair, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039176, CAB072836" Approved Supported Approved Nucleoplasm,Cytosol NA NA 630000 "Nucleoplasm, Cytosol" "CAB072836: , HPA039176: AB_10674980" "unprognostic (2.50e-1)" "unprognostic (5.70e-3)" "unprognostic (3.93e-2)" "unprognostic (1.63e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.45e-1)" "unprognostic (1.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (6.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.84e-2)" "unprognostic (1.82e-1)" 19.8 24.7 41.9 24.1 61.6 32.6 20.8 41.8 101.9 24.3 25.0 31.9 22.3 24.7 21.9 23.6 37.8 34.5 21.6 31.6 46.9 37.8 27.2 27.6 23.0 31.9 33.1 45.4 23.4 23.0 26.0 21.6 30.7 60.4 23.8 24.1 24.2 30.4 27.7 26.7 36.9 26.0 23.1 26.7 25.7 23.9 22.1 21.2 27.8 29.9 24.5 32.8 27.1 22.9 46.0 60.8 56.1 71.3 44.8 64.5 78.2 30.7 55.7 30.7 27.2 20.8 23.0 23.7 18.6 27.6 41.4 30.6 37.4 29.5 16.4 35.3 29.8 36.0 38.6 39.7 46.3 25.7 19.0 30.7 27.4 33.5 47.3 29.2 27.1 30.0 24.4 30.1 31.6 20.2 21.5 39.0 15.3 19.1 18.6 27.7 63.4 29.6 35.9 36.1 26.1 26.5 24.3 12.0 28.1 43.0 45.1 23.3 33.6 21.0 32.3 33.9 22.0 50.1 24.0 28.1 22.1 21.5 29.5 24.4 22.0 13.8 23.6 28.6 17.7 21.1 55.1 56.3 54.3 53.1 71.3 41.4 46.0 49.1 48.6 60.8 41.9 38.4 42.6 56.1 44.8 60.9 42.1 64.5 78.2 41.9 61.6 41.8 101.9 46.9 37.8 33.1 45.4 60.4 21.2 17.9 66.5 50.3 60.6 42.8 41.6 27.7 35.7 62.9 52.4 43.6 37.3 125.6 63.0 73.0 63.0 39.3 99.3 23.3 74.8 89.9 46.6 44.0 46.3 28.0 78.9 28.6 84.2 34.4 55.6 67.0 31.7 66.2 49.0 114.6 62.4 40.9 72.8 56.1 24.1 69.5 48.4 25.8 45.3 45.7 63.7 45.9 162.9 67.3 48.9 63.9 OTUB2 "C14orf137, FLJ21916, MGC3102" ENSG00000089723 "OTU deubiquitinase, ubiquitin aldehyde binding 2" Q96DC9 14 94026329-94048930 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.5" "Group enriched" "Detected in many" 9 "Early spermatids: 657.5;Late spermatids: 1026.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 2.5;myeloid DC: 3.3;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.3;monocytes: 2.5" "Cell line enhanced" "Detected in many" "GAMG: 14.5;Karpas-707: 15.7;OE19: 15.3;RPTEC TERT1: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002329, HPA075090" Enhanced NA NA "HPA002329: AB_1079537, HPA075090: AB_2686734" "unprognostic (6.80e-3)" "unprognostic (1.39e-3)" "unprognostic (3.68e-3)" "unprognostic (4.82e-3)" "unprognostic (1.66e-1)" "unprognostic (2.20e-1)" "unprognostic (2.30e-3)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (3.09e-3)" "unprognostic (2.80e-2)" "unprognostic (1.16e-2)" "unprognostic (6.25e-3)" "unprognostic (1.15e-1)" "unprognostic (2.06e-2)" "unprognostic (1.02e-4)" "unprognostic (3.16e-1)" 2.3 1.3 2.6 0.5 3.3 0.4 1.7 1.0 5.3 2.9 1.0 0.8 1.9 0.7 1.7 1.4 5.2 1.2 0.8 0.4 3.3 1.1 1.7 1.5 0.7 0.6 0.8 1.3 1.6 1.7 4.6 1.0 6.2 1.4 1.2 1.6 0.8 1.9 0.5 0.3 9.5 0.7 0.6 1.0 0.6 1.0 34.5 0.5 0.0 0.6 1.0 2.6 1.7 2.0 0.2 3.3 0.2 2.5 0.0 0.5 0.9 1.1 3.1 2.1 2.0 0.8 0.7 2.4 0.4 0.3 1.2 1.8 0.7 5.1 0.3 2.0 0.5 14.5 0.2 2.8 1.5 1.0 0.7 1.2 0.0 0.3 3.2 1.2 0.0 0.5 0.5 1.9 0.4 0.8 1.6 1.4 2.8 0.1 15.7 0.6 1.1 0.1 0.3 0.6 15.3 2.6 0.1 0.2 0.8 9.9 1.4 1.6 1.1 0.6 0.7 1.6 1.5 5.5 0.7 1.4 0.8 2.5 0.6 0.8 2.6 1.8 0.0 1.5 0.7 1.2 0.0 2.1 0.0 0.3 2.5 0.0 0.2 0.4 0.5 3.3 0.0 0.2 0.0 0.2 0.0 1.9 0.1 0.2 0.9 2.6 3.3 1.0 5.3 3.3 1.1 0.8 1.3 1.4 0.5 0.0 0.3 0.0 0.6 0.1 1.6 0.3 0.0 1.4 1.2 0.0 0.0 3.1 1.7 3.6 657.5 0.0 0.7 0.0 1.4 1.2 0.5 0.5 0.0 0.8 1.3 0.0 0.0 0.0 1.2 1026.7 6.4 2.8 0.0 0.0 0.6 0.8 3.5 0.6 3.2 1.1 1.2 6.5 0.1 6.6 4.0 1.9 98.3 0.0 0.6 2.0 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439458-23442390 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.8;tongue: 61.1" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 124.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.3;HaCaT: 23.8;SiHa: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: AB_2676049, HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favorable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 11.6 9.2 5.9 8.5 6.9 39.3 14.7 9.7 9.5 13.8 8.8 9.3 6.9 4.9 9.8 10.0 8.2 9.0 9.9 25.9 6.0 5.9 14.7 7.3 26.6 11.0 6.2 6.7 10.9 6.5 12.8 7.8 11.5 5.4 8.0 5.8 9.8 6.4 6.2 60.8 17.5 7.9 7.3 6.5 13.1 16.9 9.9 5.8 8.1 14.9 61.1 12.3 12.7 10.5 3.5 1.0 5.1 4.0 0.2 3.5 0.5 3.0 1.5 1.6 0.7 6.4 3.2 2.1 1.2 2.7 3.0 2.7 0.6 25.3 1.4 2.7 1.6 1.0 23.8 1.7 3.0 2.0 10.7 4.6 0.0 3.7 0.9 5.6 0.2 2.1 3.3 13.2 0.9 4.2 2.6 1.0 1.5 0.3 10.1 1.6 1.5 0.9 0.9 1.2 1.7 0.8 1.5 7.3 1.4 3.9 2.6 0.7 1.7 15.4 2.7 7.0 4.4 1.1 2.2 1.8 1.7 2.4 4.6 0.5 5.0 9.2 0.7 2.6 1.0 0.7 5.1 1.6 2.6 0.8 1.7 1.0 1.9 1.5 0.8 1.0 3.5 1.2 1.7 3.6 0.2 4.0 0.6 3.5 0.5 5.9 6.9 9.7 9.5 6.0 5.9 6.2 6.7 5.4 5.8 62.5 14.4 35.3 7.1 28.4 17.9 124.4 10.2 8.1 4.5 5.2 2.0 2.2 10.0 5.5 7.1 15.7 28.0 0.0 6.1 2.7 16.0 9.2 5.7 7.2 41.9 50.9 5.8 16.5 44.2 4.7 6.1 61.4 32.1 1.8 19.7 27.9 10.6 14.4 12.4 18.8 24.4 6.5 18.9 6.7 2.8 26.7 6.6 10.1 12.6 5.9 OTUD3 "DUBA4, KIAA0459" ENSG00000169914 "OTU deubiquitinase 3" Q5T2D3 1 19882513-19912945 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028543, HPA028544" Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA Cytosol "Nucleoplasm, Intermediate filaments" "HPA028543: AB_10599302, HPA028544: AB_10602277" "unprognostic (6.45e-3)" "unprognostic (9.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" "unprognostic (3.16e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-3)" "unprognostic (4.99e-2)" "unprognostic (1.09e-1)" "unprognostic (8.81e-2)" "unprognostic (4.68e-2)" "unprognostic (1.08e-1)" "unprognostic (9.83e-2)" "unprognostic (1.94e-1)" "unprognostic (7.28e-2)" "unprognostic (2.21e-2)" 6.5 11.0 15.0 6.9 19.2 11.4 10.0 19.3 23.2 10.6 8.9 6.6 6.4 10.2 14.2 13.0 6.1 8.2 7.2 5.2 12.6 7.3 7.1 4.8 8.5 7.0 9.9 12.5 11.2 7.2 9.3 20.2 5.4 9.0 9.8 8.3 6.9 6.2 9.2 9.2 13.0 9.6 11.9 8.1 7.7 7.3 28.4 9.7 6.0 6.9 2.9 6.3 7.0 7.6 1.7 0.6 0.8 0.4 0.6 2.2 0.3 5.1 1.9 8.7 10.4 3.8 3.3 8.6 5.5 3.2 2.8 2.8 9.1 4.9 8.1 4.5 12.1 2.0 5.0 8.1 3.2 5.5 5.3 10.8 7.8 10.4 6.3 2.1 5.7 7.2 2.7 3.2 4.4 5.7 6.0 3.7 8.3 5.5 3.5 4.8 2.8 4.3 5.7 4.1 4.1 5.1 10.1 22.3 3.0 4.7 5.6 7.7 5.5 3.9 3.2 4.2 8.9 4.8 4.2 4.5 6.8 8.7 7.5 4.7 4.0 3.4 5.0 4.8 7.6 3.1 0.8 0.4 0.1 1.5 0.3 1.4 1.7 1.7 1.4 0.3 1.3 2.2 1.8 0.7 0.6 0.1 0.6 0.9 0.3 15.0 19.2 19.3 23.2 12.6 7.3 9.9 12.5 9.0 9.7 14.9 6.9 3.0 5.2 12.6 13.5 3.6 0.0 10.7 1.2 8.7 15.7 2.3 0.0 4.5 9.9 4.5 3.8 0.0 4.0 4.7 4.2 8.8 1.1 2.1 1.6 25.4 11.5 9.2 1.6 11.5 5.2 3.3 5.0 2.8 6.7 10.2 3.9 5.9 5.6 3.4 16.0 6.5 3.5 19.1 21.2 7.8 2.1 4.4 5.9 3.0 OTUD4 "DUBA6, HSHIN1, KIAA1046" ENSG00000164164 "OTU deubiquitinase 4" Q01804 4 145110838-145180161 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036623 Uncertain Supported Cytosol NA NA Cytosol "HPA036623: AB_10696780" "unprognostic (1.67e-1)" "unprognostic (4.18e-2)" "unprognostic (3.41e-2)" "unprognostic (1.95e-1)" "unprognostic (2.80e-1)" "unprognostic (4.06e-2)" "unprognostic (3.42e-2)" "unprognostic (2.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-2)" "unprognostic (5.21e-3)" "unprognostic (2.03e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.62e-1)" 14.3 11.8 16.6 11.6 16.7 24.7 12.0 22.7 15.9 14.0 15.3 16.0 10.1 10.0 13.9 13.3 14.8 14.9 11.2 15.6 12.0 9.2 11.1 17.7 15.5 13.1 14.1 8.4 14.3 13.4 22.4 12.2 17.9 12.7 10.6 11.2 10.6 12.7 11.0 36.2 13.6 16.2 12.4 10.1 13.5 10.8 26.8 18.8 13.1 13.4 13.6 12.3 11.5 12.8 3.3 2.8 2.8 2.8 1.6 3.5 1.0 15.2 8.7 10.5 9.6 12.4 15.1 14.0 13.3 15.1 17.3 13.8 9.4 18.9 28.1 6.1 18.7 10.6 9.3 18.0 18.7 22.7 12.0 8.6 13.4 10.6 8.5 14.5 28.2 10.2 11.8 19.1 21.1 27.7 14.6 15.2 12.4 22.2 21.1 16.9 9.1 17.4 12.3 11.6 14.8 10.0 14.4 11.5 6.6 16.7 11.2 10.1 8.3 12.3 18.7 13.3 14.4 6.2 11.6 18.3 19.5 12.4 10.0 17.7 15.6 15.3 18.6 13.5 20.1 18.8 0.0 1.7 2.8 3.5 2.1 2.6 3.3 2.7 2.8 1.6 2.4 2.7 2.4 0.5 1.6 2.8 2.8 2.0 1.0 16.6 16.7 22.7 15.9 12.0 9.2 14.1 8.4 12.7 18.8 59.6 19.7 15.9 40.5 56.1 15.3 18.5 28.1 42.8 23.9 26.2 23.6 17.2 8.3 11.1 130.8 21.8 10.5 0.0 12.7 17.3 25.9 44.8 19.7 20.2 11.8 6.4 14.6 22.1 18.0 63.1 18.7 17.9 30.4 5.4 12.1 7.5 18.4 14.0 28.3 6.6 19.1 0.0 29.9 28.8 41.0 47.6 13.4 14.6 14.3 50.2 OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922028-48958386 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/70: 187.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: AB_1854844" "unprognostic (9.73e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.67e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (6.65e-2)" "unprognostic (2.33e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "prognostic favorable (8.20e-4)" "unprognostic (1.32e-1)" "unprognostic (3.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-2)" "unprognostic (5.05e-3)" 23.5 27.5 32.4 26.8 40.9 38.4 21.9 35.0 52.4 21.3 22.9 28.2 23.4 30.5 25.5 26.8 20.5 25.1 20.9 16.6 29.8 31.3 22.6 24.5 25.2 30.8 25.4 29.8 30.0 25.4 29.6 26.8 23.1 29.4 24.0 17.8 20.4 26.9 27.4 24.4 24.5 29.1 27.1 21.4 34.5 22.3 12.7 24.0 34.8 24.5 14.4 27.2 22.1 22.7 7.8 6.3 8.6 5.1 18.6 7.5 3.5 6.2 9.5 4.4 11.0 7.5 6.8 5.2 5.5 6.5 7.0 7.6 4.7 7.0 7.0 3.6 6.9 6.1 7.7 6.7 5.6 6.5 8.2 8.1 5.3 9.6 5.4 6.4 5.0 5.9 7.5 5.2 7.2 4.9 7.7 5.5 5.8 6.7 11.1 4.9 6.3 7.9 10.9 8.0 2.3 7.5 6.3 6.5 9.1 4.9 5.6 4.3 7.6 7.3 4.7 7.3 10.8 6.3 4.6 7.8 4.6 5.8 12.0 4.5 187.1 46.7 6.7 7.0 7.1 3.1 5.2 3.4 7.0 7.0 5.1 5.8 7.8 5.5 6.0 4.8 6.0 5.2 7.5 8.6 18.6 4.7 6.3 7.0 3.5 32.4 40.9 35.0 52.4 29.8 31.3 25.4 29.8 29.4 24.0 8.9 21.1 23.0 19.4 19.7 31.7 8.5 10.2 17.4 17.0 26.2 25.5 11.3 8.3 13.0 1.5 18.5 26.4 0.0 15.9 12.0 16.5 23.0 6.9 22.9 14.5 27.0 46.2 18.4 24.7 1.5 19.2 19.5 25.3 21.6 26.6 16.0 17.8 15.8 22.3 20.3 25.0 12.9 13.3 5.9 10.9 22.3 25.7 30.9 17.4 22.8 OTUD6A "DUBA2, FLJ25831, HSHIN6" ENSG00000189401 "OTU deubiquitinase 6A" Q7L8S5 X 70062491-70064179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "blood: 3.8;testis: 13.6" "Group enriched" "Detected in some" 7 "Spermatocytes: 20.9;Spermatogonia: 6.6" "Cancer enriched" "Detected in single" 57 "testis cancer: 2.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.8" "Cell line enhanced" "Detected in some" "MCF7: 2.0;U-2 OS: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA053304 Enhanced Approved Vesicles,Cytosol NA NA Cytosol Vesicles "HPA053304: AB_2682107" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 13.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.4 3.8 0.4 0.7 0.6 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.6 0.4 1.0 0.5 0.0 0.7 0.8 0.4 0.3 0.2 0.0 0.0 0.5 0.8 0.8 0.0 0.3 0.7 0.3 0.4 0.2 0.3 0.2 0.0 1.1 0.2 0.6 0.0 2.0 0.3 0.9 0.6 0.0 0.2 0.0 0.0 0.0 0.8 0.7 0.6 0.3 0.5 0.2 0.0 0.5 0.1 0.1 0.0 0.2 1.9 0.3 0.5 1.6 0.3 1.5 0.1 0.2 0.2 3.8 0.4 0.3 0.4 0.2 0.4 0.3 0.3 0.2 0.0 0.9 0.3 0.6 2.6 0.7 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.4 0.3 1.1 0.0 0.1 0.0 0.0 0.0 1.2 0.7 0.3 0.5 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 1.9 0.0 0.0 20.9 6.6 0.5 0.2 0.0 0.0 0.3 OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU domain containing 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: AB_10600925, HPA024503: AB_1854845, HPA024772: AB_1854846" "prognostic unfavorable (7.50e-4)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (4.78e-3)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.16e-3)" "unprognostic (2.17e-1)" "unprognostic (5.51e-2)" "unprognostic (1.27e-2)" "unprognostic (8.61e-3)" "unprognostic (1.87e-2)" "unprognostic (1.96e-1)" "unprognostic (4.53e-1)" "unprognostic (8.78e-2)" "unprognostic (5.71e-2)" 11.4 11.3 14.6 14.1 18.2 8.9 13.2 13.8 19.6 12.3 11.3 9.9 10.3 9.2 12.1 9.0 13.2 9.1 8.6 14.0 14.9 13.7 11.0 10.5 10.0 13.8 18.5 15.5 12.5 9.9 11.2 14.4 14.9 16.2 11.6 11.3 6.0 9.5 14.8 35.3 11.2 9.1 12.4 19.9 11.3 8.8 11.9 17.4 13.9 11.8 11.0 11.9 11.9 14.0 7.2 12.9 8.8 7.8 7.8 6.8 2.9 16.3 9.4 8.5 6.3 3.8 2.9 8.8 13.0 4.9 12.1 7.9 8.1 10.3 17.3 6.3 6.8 4.9 5.6 17.5 10.6 18.8 13.9 10.7 23.6 9.8 6.1 8.2 12.0 12.5 4.8 5.1 9.7 23.1 7.2 9.8 13.7 23.6 10.9 10.3 8.9 20.1 7.9 4.5 12.5 18.7 9.1 8.1 15.5 9.4 11.8 2.0 7.6 1.2 28.8 12.5 11.5 14.7 5.8 10.0 7.2 10.9 11.0 12.3 10.9 20.7 25.5 10.6 15.1 13.8 8.8 6.5 4.3 5.9 7.8 6.8 7.2 4.8 5.7 8.1 6.8 6.7 5.9 0.9 7.8 5.8 12.9 3.6 2.9 14.6 18.2 13.8 19.6 14.9 13.7 18.5 15.5 16.2 17.4 8.9 9.9 12.4 5.2 20.6 13.1 14.0 10.2 9.4 13.6 1.8 31.4 9.3 8.3 4.7 0.4 7.5 3.1 0.0 4.3 8.3 5.1 4.0 18.4 9.2 7.0 11.1 10.4 9.2 7.5 0.9 8.9 9.4 3.3 8.2 4.2 13.4 5.3 4.2 3.9 6.2 16.7 0.0 7.2 1.9 6.6 15.8 5.6 7.9 5.6 4.7 OTUD7A "C15orf16, CEZANNE2, OTUD7" ENSG00000169918 "OTU deubiquitinase 7A" Q8TE49 15 31475398-31870789 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4" "Group enriched" "Detected in many" 4 "Bipolar cells: 20.5;Horizontal cells: 23.8;Spermatogonia: 6.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044554 Uncertain Approved Nucleoli,Cytosol NA NA "Nucleoli, Cytosol" "HPA044554: AB_10794895" "unprognostic (3.61e-2)" "unprognostic (1.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.25e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (3.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.79e-11)" "unprognostic (6.78e-2)" "unprognostic (2.76e-1)" "unprognostic (8.27e-2)" "unprognostic (1.79e-1)" 2.6 2.0 12.4 1.7 13.9 5.9 1.5 13.2 17.0 1.8 3.4 16.0 0.0 1.5 1.9 1.9 1.9 2.0 2.3 2.1 10.0 4.6 2.3 1.0 1.5 3.5 20.4 7.1 2.0 2.5 4.6 1.7 0.9 10.5 1.2 3.1 0.7 1.6 2.0 1.8 3.2 2.1 2.9 9.1 2.2 2.3 8.2 17.4 0.0 2.3 0.0 2.4 1.9 1.3 0.1 3.2 0.3 1.4 0.1 0.7 0.4 3.7 4.1 4.5 6.1 0.4 1.3 3.2 2.5 1.3 3.9 2.0 2.5 3.2 2.9 2.2 0.9 2.2 4.6 4.9 2.1 3.2 5.9 6.6 3.7 8.3 2.0 0.3 4.1 5.8 0.0 0.2 3.9 4.3 1.1 3.5 6.4 6.0 5.5 1.8 2.9 3.1 3.9 2.1 4.8 2.0 5.7 3.1 1.4 1.6 3.9 11.0 6.0 3.4 3.0 1.0 2.3 2.5 4.3 2.3 5.4 5.3 3.0 6.3 3.4 2.4 3.0 2.9 5.8 4.5 0.0 0.4 0.3 0.6 0.5 0.3 0.0 0.3 0.7 0.2 0.1 0.2 0.2 0.0 0.1 1.4 3.2 0.0 0.4 12.4 13.9 13.2 13.8 10.0 4.6 20.4 7.1 10.5 17.4 3.0 0.0 0.0 0.6 0.3 20.5 2.2 0.0 0.0 1.2 1.8 2.0 0.0 0.0 0.4 1.0 1.0 0.9 0.0 0.8 0.0 0.7 1.3 0.0 0.8 0.2 23.8 3.5 1.3 0.0 1.1 0.9 0.0 1.7 0.0 1.0 3.7 0.4 0.0 2.5 1.2 2.9 0.0 1.0 4.1 6.1 0.4 0.1 0.0 1.0 0.8 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010676 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 100.1" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.7" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;NK-cells: 1.4;T-cells: 2.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" NA NA Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: AB_1854847, HPA076357: " "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favorable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favorable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 8.8 6.2 5.8 2.6 12.3 0.3 6.2 8.5 8.9 8.6 6.3 20.6 4.0 4.6 8.5 4.1 6.1 7.6 4.3 5.3 6.0 4.5 8.6 5.6 0.9 12.7 5.1 9.2 4.5 12.5 4.3 5.3 11.6 5.3 5.6 7.4 5.4 6.3 13.2 4.3 5.1 8.9 8.5 2.3 5.2 9.6 12.5 0.0 8.3 2.3 2.1 6.3 7.1 0.6 0.6 4.7 0.3 1.4 2.3 0.2 11.5 9.3 6.5 10.9 8.6 8.1 6.2 8.2 12.0 9.8 6.8 6.8 9.4 0.1 5.3 14.8 4.4 9.2 9.2 9.0 10.4 11.1 4.7 4.4 12.9 4.6 9.2 5.0 4.9 8.9 7.0 16.6 14.6 7.7 8.0 1.4 12.1 12.6 7.0 11.8 0.9 1.4 8.3 8.7 9.1 1.2 9.0 2.9 3.8 15.9 4.2 8.0 14.4 10.6 12.9 8.9 8.8 2.7 9.5 10.2 9.5 6.8 9.5 13.5 13.0 1.3 9.1 1.5 16.7 4.7 0.3 1.3 2.3 0.2 1.7 0.6 1.0 1.4 0.1 0.6 0.9 1.0 1.2 1.4 0.3 0.6 0.6 0.2 32.8 9.4 2.2 22.0 14.2 25.3 16.2 12.7 12.0 15.9 10.4 100.1 16.8 6.6 11.5 56.6 14.7 19.3 23.3 9.6 7.6 13.6 16.9 0.0 29.3 2.8 22.3 16.7 12.3 0.6 57.7 13.6 2.5 35.4 7.2 12.2 25.5 16.8 21.0 21.5 10.3 66.3 0.0 11.3 10.7 6.4 14.4 17.7 6.7 9.2 21.0 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699711 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 10.0 7.4 5.9 22.6 7.8 32.3 8.4 7.2 6.6 8.2 9.3 8.3 8.9 10.7 9.5 7.7 13.8 6.1 10.8 15.5 6.7 4.9 8.5 19.5 11.1 16.0 9.6 2.8 9.1 12.2 7.5 9.8 11.8 7.0 11.1 7.0 7.7 10.6 10.8 16.5 18.1 11.7 8.1 10.5 12.5 7.1 11.5 7.4 15.0 7.8 9.7 19.3 8.5 15.8 3.4 2.9 3.1 3.0 1.0 4.6 0.9 6.4 7.5 7.5 8.5 7.0 7.3 8.3 6.5 4.6 9.3 7.0 10.1 4.8 11.6 12.8 4.2 13.4 7.4 9.3 8.5 6.4 20.0 7.7 8.3 23.9 5.4 6.0 7.9 14.3 4.1 10.5 7.6 6.5 5.1 7.8 9.8 8.2 18.6 6.6 4.0 7.8 6.9 4.6 6.8 8.0 12.1 6.8 4.6 6.0 6.7 3.4 5.6 23.1 5.2 5.0 9.6 5.7 9.1 7.2 12.1 13.7 9.0 8.5 8.4 12.7 13.2 6.9 15.1 6.2 0.4 2.0 3.1 1.0 2.2 3.0 0.9 2.5 3.4 2.9 3.4 1.8 3.9 2.2 1.0 3.0 2.5 4.6 0.9 5.9 7.8 7.2 6.6 6.7 4.9 9.6 2.8 7.0 7.4 3.0 8.6 13.4 20.2 0.0 10.9 13.4 15.3 9.4 7.9 5.2 13.7 13.2 6.6 4.2 7.3 8.7 13.9 0.0 5.0 8.6 4.9 19.7 10.3 32.7 12.3 7.9 9.1 8.0 11.8 2.5 9.8 10.6 0.0 13.6 11.6 13.0 7.1 8.4 6.0 8.9 32.3 0.0 6.2 23.8 30.4 0.0 11.9 15.0 8.9 19.3 PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205126-17246005 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 48.7;lymphoid tissue: 60.2" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 12.6;Extravillous trophoblasts: 10.0;Urothelial cells: 3.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.5;EFO-21: 4.6;HaCaT: 2.9;LHCN-M2: 3.6;RPTEC TERT1: 4.9" "Region enhanced" "Detected in single" "olfactory region: 0.5" "Not detected" "Not detected" HPA062294 Enhanced Approved Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA062294: AB_2684741" "unprognostic (9.30e-2)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.40e-1)" "unprognostic (5.22e-2)" "unprognostic (7.27e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (7.75e-2)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "prognostic unfavorable (8.34e-11)" "unprognostic (2.00e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.3 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.1 0.0 4.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.1 60.2 1.3 6.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.2 0.0 0.1 9.5 0.0 4.6 0.4 0.4 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 4.9 0.4 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 12.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 3.8 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119435 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.7;skeletal muscle: 126.4" "Cell type enhanced" "Detected in many" 9 "Cone photoreceptor cells: 90.3;monocytes: 42.3;Mucus-secreting cells: 71.1;Paneth cells: 95.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.1;neutrophil: 37.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.2" "Cell line enhanced" "Detected in some" "A549: 6.9;RPTEC TERT1: 20.3;SK-BR-3: 31.1;T-47d: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 1.4 16.2 5.0 25.1 10.9 19.2 3.3 25.6 2.7 41.4 76.7 1.3 1.6 1.4 1.3 3.8 2.3 1.8 1.1 21.9 15.6 5.5 1.3 2.2 1.4 36.8 13.6 1.1 1.7 1.3 1.5 1.6 45.6 2.3 43.4 4.6 21.1 1.8 126.4 2.8 3.6 3.9 69.6 4.2 2.1 1.3 26.0 0.0 1.2 14.8 1.6 2.1 0.7 0.0 4.2 37.2 5.1 0.0 0.0 1.7 0.0 6.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 2.9 0.1 0.9 0.3 0.1 0.9 0.2 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 2.2 0.3 0.8 1.0 2.3 0.0 0.0 0.0 0.2 20.3 0.0 1.2 0.1 0.0 31.1 0.0 1.8 8.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.4 5.1 15.1 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 37.2 0.0 0.1 0.1 0.0 1.7 16.2 25.1 3.3 22.0 21.9 15.6 36.8 13.6 45.6 26.0 0.0 2.2 0.0 0.2 0.2 2.2 0.3 0.0 0.0 2.3 1.8 90.3 0.1 10.0 0.5 5.7 0.0 25.6 0.0 0.0 0.4 0.4 0.3 16.2 0.0 7.6 0.0 3.5 1.3 6.8 8.5 0.3 4.8 27.0 42.3 71.1 30.6 0.0 95.1 0.7 0.2 29.3 0.0 1.0 0.2 0.3 0.4 0.1 0.0 21.7 0.1 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.5;smooth muscle: 9.4;urinary bladder: 28.0" "Group enriched" "Detected in some" 5 "Collecting duct cells: 1.8;Urothelial cells: 6.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 13.5;RT4: 16.2;T-47d: 12.2;U-87 MG: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.1 0.0 0.0 3.2 10.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 6.4 0.0 2.3 0.0 9.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 28.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 13.5 0.0 1.3 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 16.2 0.0 0.0 0.0 2.4 0.1 0.1 12.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 48.2;bone marrow: 54.8;lymphoid tissue: 24.2" "Cell type enhanced" "Detected in some" 21 "Alveolar cells type 2: 5.9;granulocytes: 11.6;Kupffer cells: 4.7;Spermatogonia: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "basophil: 17.0;classical monocyte: 18.6;eosinophil: 24.6;neutrophil: 48.2" "Group enriched" "Detected in many" 9 "granulocytes: 48.2;monocytes: 18.6" "Cell line enhanced" "Detected in some" "BEWO: 1.8;HEL: 4.2;NB-4: 1.7;RPMI-8226: 4.9" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 12000 "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.2 0.2 0.3 0.5 0.2 54.8 0.2 0.1 0.8 0.2 0.2 0.5 0.0 0.2 0.2 0.1 0.4 0.9 0.4 9.8 0.6 0.1 0.3 1.2 9.7 5.2 1.8 0.0 0.9 0.3 0.1 0.6 4.1 0.6 0.1 0.2 0.9 0.5 0.1 0.2 0.2 0.2 0.4 0.2 24.2 0.3 1.0 0.3 2.6 0.6 0.2 0.2 0.4 7.5 0.4 3.6 48.2 18.6 1.1 1.2 8.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.2 0.0 4.2 0.1 0.4 0.0 0.4 0.6 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.0 1.7 0.2 0.0 0.2 0.2 0.0 4.9 0.0 0.3 0.2 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.1 0.0 0.2 0.5 0.1 17.0 18.6 24.6 0.1 1.4 0.0 0.2 0.1 0.2 3.6 0.4 0.7 1.2 48.2 1.1 0.4 1.6 0.1 8.1 0.3 0.2 0.1 0.8 0.6 0.1 1.8 0.0 0.6 0.3 0.0 5.9 2.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 11.6 0.0 0.2 0.0 0.0 0.0 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.5 0.0 0.0 PADI6 ENSG00000276747 "Peptidyl arginine deiminase 6" Q6TGC4 1 17372196-17401699 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "blood: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected" "Not detected" NA NA "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (3.02e-2)" "unprognostic (6.56e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.8 0.0 1.9 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 0.1 0.0 0.0 0.2 1.1 3.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144267-117176894 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 1600000 Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 21.5 34.1 30.6 19.2 29.7 33.5 32.3 43.5 41.3 21.6 20.2 33.3 12.7 21.1 23.4 22.8 23.3 20.8 19.3 26.2 31.9 36.8 24.6 22.5 20.5 17.7 39.3 31.6 23.6 23.0 23.1 24.2 26.9 39.6 22.2 19.6 17.3 19.3 17.4 14.1 20.8 18.0 19.9 51.6 18.3 21.4 29.9 26.3 15.1 30.9 10.8 20.4 25.9 20.3 26.8 21.6 36.8 35.7 18.9 31.4 26.9 15.0 17.2 19.9 28.7 22.2 15.6 15.5 25.3 22.1 14.1 12.9 31.4 33.2 16.2 36.3 30.3 14.1 24.1 28.9 32.7 18.6 14.5 11.1 41.8 15.7 20.1 19.9 14.4 16.0 17.2 25.9 28.1 35.5 15.4 23.0 9.1 22.1 12.4 21.5 9.6 13.9 21.2 18.2 20.9 13.6 15.6 22.5 17.8 21.5 23.5 22.2 29.4 29.2 22.1 9.6 17.6 24.6 12.4 36.8 25.8 17.1 12.6 17.9 3.9 6.0 21.8 10.4 27.7 21.6 32.1 30.8 26.7 24.2 33.3 28.2 26.8 28.0 25.3 21.6 25.4 29.3 31.4 36.8 18.9 35.7 15.8 19.5 26.9 30.6 29.7 43.5 37.8 31.9 36.8 39.3 31.6 39.6 26.3 26.8 33.3 41.0 38.7 108.6 36.9 31.1 68.8 17.4 26.1 62.8 45.2 36.3 39.7 52.6 7.3 54.4 31.6 0.0 34.5 77.2 42.9 53.9 18.5 39.2 38.5 44.5 79.3 57.7 59.6 8.9 42.0 55.7 47.2 49.5 37.2 33.5 72.8 46.7 32.2 44.8 33.5 12.9 46.4 45.1 75.6 101.4 45.7 38.5 39.1 38.8 PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Spermatogonia: 212.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" NA NA 370000 "Intermediate filaments" "HPA035639: AB_10670163" "unprognostic (3.19e-1)" "unprognostic (5.38e-3)" "unprognostic (1.13e-1)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" "unprognostic (6.36e-2)" "unprognostic (2.37e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (2.68e-1)" "unprognostic (3.21e-2)" "unprognostic (4.56e-2)" "unprognostic (6.80e-3)" 4.5 12.8 23.8 10.4 23.2 20.7 12.2 36.4 24.9 17.2 14.6 7.8 8.0 10.9 10.1 11.9 15.5 13.5 9.6 4.6 15.4 25.7 11.7 5.6 5.8 13.6 13.9 13.1 15.4 11.9 8.3 11.8 5.8 12.4 10.3 10.7 11.2 9.8 6.1 10.8 10.6 11.2 6.6 11.7 9.5 11.3 16.3 11.3 37.4 7.8 13.8 15.4 14.6 10.9 19.6 24.6 8.7 13.6 7.8 27.4 10.5 29.3 53.8 33.6 35.9 0.7 1.8 10.4 7.4 10.2 24.3 25.2 17.9 24.7 18.1 9.7 8.9 16.9 10.0 15.2 19.4 10.1 27.4 20.8 21.9 14.4 24.0 5.2 13.9 24.4 5.3 9.0 14.9 7.0 13.5 10.8 39.7 15.4 21.6 17.7 42.9 31.0 10.9 18.6 34.8 0.0 23.0 12.9 16.2 19.7 31.0 38.7 30.3 11.8 23.4 12.3 11.1 29.2 15.9 5.8 20.2 27.4 1.8 19.9 10.3 21.3 15.4 11.3 22.5 17.7 8.7 13.6 7.2 12.1 10.7 16.1 19.6 17.3 13.9 24.6 18.4 23.0 16.0 1.8 7.8 5.4 13.6 27.4 10.5 23.8 23.2 36.4 24.9 15.4 25.7 13.9 13.1 12.4 11.3 14.9 9.1 22.3 37.0 25.0 24.5 1.2 28.1 30.8 15.9 31.4 13.7 30.1 68.0 88.9 12.7 17.1 21.2 23.3 48.0 33.8 21.6 29.7 27.6 7.2 52.3 11.1 56.6 9.2 23.0 16.4 12.7 23.2 43.9 10.8 47.4 24.0 78.6 24.6 8.5 40.4 17.2 0.0 6.2 4.3 212.2 15.6 11.3 17.5 63.6 43.4 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998157 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA NA "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favorable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 6.5 8.8 8.9 6.3 11.0 4.1 7.0 10.7 9.0 7.0 12.3 11.9 7.8 13.2 5.7 7.7 8.7 6.4 10.1 6.7 8.0 4.5 15.5 20.9 6.3 5.5 10.7 5.1 4.7 34.7 14.8 13.6 7.8 9.8 6.8 13.0 9.6 9.0 5.0 19.3 9.5 25.3 5.2 9.8 7.9 11.6 8.4 11.1 4.4 13.6 6.3 11.4 6.5 6.3 2.4 18.9 28.0 3.3 8.3 12.3 3.9 5.2 6.7 4.2 4.8 8.8 7.0 8.7 6.0 3.1 5.4 3.6 2.7 11.2 2.3 7.5 3.5 5.2 4.7 6.3 5.8 7.0 4.7 3.8 3.8 2.9 5.3 5.3 2.0 33.5 4.5 13.2 8.3 5.6 3.0 5.2 5.6 5.3 4.5 7.2 2.3 6.2 1.9 8.4 18.2 3.7 5.1 4.0 5.2 8.7 1.8 5.1 4.3 3.5 4.8 11.0 7.3 8.0 3.6 4.8 3.8 4.7 7.9 4.7 8.3 10.7 3.0 8.0 8.1 12.6 12.7 3.3 28.0 12.3 3.1 7.8 1.8 4.3 7.9 2.4 2.4 5.6 7.9 3.0 8.3 1.1 18.9 4.3 3.9 8.9 11.0 10.7 9.0 8.0 4.5 10.7 5.1 9.8 11.1 14.9 13.8 2.9 1.9 1.3 8.5 6.5 12.7 9.4 14.8 17.4 25.5 9.5 3.3 11.1 0.6 3.6 36.7 0.0 6.4 7.5 3.6 5.1 26.6 19.7 9.8 4.8 7.5 5.5 10.5 1.0 2.3 6.0 8.5 5.4 17.1 5.8 10.2 11.5 2.5 15.7 9.3 6.5 2.1 17.0 9.6 3.3 8.4 12.8 16.5 3.8 PAN2 "hPAN2, KIAA0710, USP52" ENSG00000135473 "PAN2 poly(A) specific ribonuclease subunit" Q504Q3 12 56316223-56334053 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (9.10e-3)" "unprognostic (1.03e-1)" "unprognostic (7.28e-2)" "unprognostic (7.35e-3)" "unprognostic (3.80e-1)" "unprognostic (1.74e-3)" "unprognostic (4.23e-3)" "prognostic unfavorable (2.77e-4)" "unprognostic (4.19e-1)" "unprognostic (3.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" 8.1 13.4 12.8 7.1 17.7 7.4 9.9 21.7 17.6 9.6 9.5 16.1 16.4 11.0 11.2 17.6 7.4 11.3 7.8 9.8 13.9 5.1 9.7 17.6 8.7 9.0 19.7 7.0 17.8 12.9 24.3 30.7 9.2 14.6 9.1 9.6 12.6 10.0 14.1 9.1 9.4 10.7 8.8 16.4 10.6 10.5 18.2 19.4 15.3 20.2 4.8 11.0 11.0 9.2 3.1 7.6 3.9 8.1 3.8 5.2 3.4 2.8 4.4 10.8 3.5 9.5 10.8 7.1 2.2 3.0 5.0 2.3 2.6 5.7 7.9 8.6 4.3 2.7 6.0 12.7 8.4 2.8 3.5 6.2 10.1 4.2 2.5 8.4 2.2 5.4 10.1 11.4 5.3 15.5 13.2 3.7 16.8 6.8 19.9 2.9 6.2 7.5 5.6 3.6 4.8 2.9 6.5 7.7 14.2 4.9 2.3 8.6 7.7 4.2 5.5 5.4 12.6 7.1 4.4 1.6 5.2 5.1 2.3 2.0 16.8 6.6 5.2 6.1 4.7 4.2 3.9 5.8 2.3 2.4 8.1 3.7 3.1 1.9 3.5 7.6 2.7 4.1 5.2 0.4 3.8 3.8 2.9 3.0 3.4 12.8 17.7 21.7 17.6 13.9 5.1 19.7 7.0 14.6 19.4 8.9 17.1 4.7 4.8 4.5 25.5 9.0 5.1 16.0 10.3 5.2 25.5 6.5 1.7 2.4 1.2 6.0 5.5 0.0 1.8 4.1 5.6 3.7 5.8 15.3 4.7 14.3 13.8 12.9 5.4 2.1 10.3 6.3 1.7 2.8 9.6 7.2 3.3 8.2 6.0 2.8 16.3 6.5 3.1 19.1 6.1 3.3 4.2 5.7 8.5 2.7 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153804-116402322 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 86 "placenta: 484.6" "Group enriched" "Detected in many" 6 "Collecting duct cells: 157.1;Proximal tubular cells: 39.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 19.3;ASC TERT1: 14.8;HSkMC: 53.2;U-138 MG: 13.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "midbrain: 10.4;olfactory region: 4.1;pons and medulla: 8.3;thalamus: 4.8" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" NA NA 41000 "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.8 2.3 0.5 1.0 0.5 0.0 0.8 0.4 0.6 3.6 2.4 0.6 1.0 0.1 3.5 1.0 3.6 2.0 1.1 3.7 0.4 0.0 4.3 0.5 2.4 0.7 0.4 0.4 1.4 0.7 5.6 0.7 484.6 0.7 1.4 0.9 0.9 0.5 1.2 0.5 1.1 0.9 2.4 0.6 0.6 1.0 0.8 0.5 0.4 1.3 1.0 1.0 2.3 3.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 5.5 8.4 0.0 19.3 14.8 0.0 4.5 8.0 1.2 2.1 0.0 0.0 0.0 0.0 3.1 0.4 0.6 0.0 0.0 6.0 0.0 0.0 0.9 4.6 0.0 9.4 0.0 0.0 53.2 0.0 6.2 0.7 10.3 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.0 2.7 0.0 0.0 10.7 13.9 0.7 0.4 0.5 0.0 0.0 0.0 9.9 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.6 0.4 0.0 0.4 0.4 0.7 0.5 0.0 1.0 0.0 0.2 2.6 5.0 2.2 0.0 0.0 2.3 157.1 11.8 0.3 8.3 5.8 14.3 0.7 0.0 0.0 0.8 7.4 16.4 0.6 1.1 0.0 0.4 0.0 0.0 5.5 0.0 12.7 13.3 0.3 1.7 0.0 0.0 2.3 0.5 0.0 8.1 39.6 2.7 0.0 8.2 1.7 0.4 1.0 11.7 0.0 0.0 0.1 PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA053007" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA Nucleoplasm "Vesicles, Cytosol" "HPA021819: AB_1854974, HPA053007: AB_2682014" "unprognostic (5.77e-3)" "unprognostic (6.74e-2)" "unprognostic (3.06e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.57e-5)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (8.34e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (5.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (8.54e-2)" "unprognostic (1.13e-1)" 4.0 5.6 4.3 4.2 5.4 1.4 5.3 7.8 6.3 4.8 5.1 6.7 4.9 3.0 6.2 4.3 3.6 6.6 4.6 5.9 9.2 5.2 3.5 5.8 4.5 4.7 3.5 8.1 4.7 5.8 4.9 6.1 4.7 5.1 8.1 6.7 5.1 4.7 4.0 5.9 4.7 5.8 4.9 6.9 4.4 4.8 6.9 7.0 12.5 7.7 8.3 9.4 5.5 12.7 10.6 18.6 13.7 9.0 11.2 13.7 12.7 14.0 14.8 14.2 8.5 11.9 9.6 8.3 10.7 6.6 14.4 15.7 8.0 15.9 14.7 14.6 9.8 8.7 9.3 10.2 14.1 8.2 7.2 15.5 12.4 20.5 10.1 9.0 12.7 16.6 8.5 11.1 7.1 15.5 12.7 18.4 7.8 24.3 18.6 21.2 11.1 11.9 8.2 12.9 16.3 10.3 16.4 13.3 18.8 18.8 7.9 9.1 9.2 11.3 9.6 14.2 9.4 14.0 20.5 15.9 15.0 6.7 12.5 6.2 3.0 5.2 5.5 7.9 6.9 7.1 6.7 7.0 6.9 9.4 9.1 3.0 8.3 7.7 5.4 5.5 5.5 8.9 11.7 8.3 4.6 5.5 13.2 23.8 12.7 29.4 12.5 12.2 25.5 6.5 8.3 6.3 3.5 8.3 8.5 23.3 5.6 5.2 6.7 4.0 13.9 9.6 8.2 4.8 6.3 7.4 13.2 3.3 6.9 7.0 3.3 9.0 8.1 8.9 6.7 2.9 7.8 27.7 20.8 0.0 5.5 15.7 12.1 5.3 3.9 7.5 9.7 3.8 PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported Nucleoplasm,Cytosol NA NA 69000000 "Nucleoplasm, Cytosol" "CAB005870: AB_444361, HPA004190: AB_1079566" "unprognostic (6.88e-3)" "unprognostic (7.50e-2)" "unprognostic (3.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (7.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (7.43e-2)" 44.6 67.9 69.3 38.1 64.9 33.7 45.4 57.2 62.7 34.0 36.4 33.4 43.2 27.3 35.8 56.6 40.9 39.0 41.6 71.7 56.9 57.2 60.5 77.1 28.6 46.1 61.6 57.2 45.9 60.4 66.6 48.4 44.6 41.2 44.7 39.5 38.6 46.5 39.4 128.7 19.8 27.5 48.1 52.5 37.5 37.2 38.2 32.2 38.8 71.6 43.3 46.5 41.3 43.4 49.5 141.8 38.8 61.0 52.8 87.2 90.6 68.3 61.6 61.4 70.6 66.1 63.6 30.1 63.7 59.8 62.8 50.7 56.2 75.0 84.8 72.1 68.4 44.1 49.2 66.2 85.2 81.6 75.5 71.6 91.2 92.1 83.3 57.1 87.0 56.2 59.9 36.4 63.9 76.9 49.2 65.7 44.7 88.5 63.2 87.0 64.1 60.5 110.6 50.1 84.9 63.7 46.6 82.5 116.3 98.4 35.2 71.9 60.4 63.7 98.5 99.5 53.8 54.9 64.8 62.3 57.9 46.2 53.4 69.8 61.4 98.5 120.8 76.4 133.2 82.0 22.7 61.0 38.8 52.6 55.4 49.7 49.5 52.7 62.2 73.9 38.6 45.6 52.4 21.0 52.8 44.1 141.8 87.2 90.6 69.3 64.9 57.2 62.7 56.9 57.2 61.6 57.2 41.2 32.2 122.1 136.9 226.3 328.5 185.6 175.5 422.7 221.7 227.5 176.3 235.5 74.6 504.6 721.2 419.3 26.4 207.3 136.6 46.7 416.0 502.3 279.0 413.5 199.9 332.4 385.8 176.4 228.6 156.5 174.9 43.1 331.6 265.8 340.8 806.1 224.5 530.4 359.6 213.9 356.1 742.4 177.0 271.7 346.0 212.8 299.8 125.7 392.7 243.9 261.6 388.0 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 24.2 20.6 26.2 19.2 30.1 21.2 30.4 22.1 29.6 22.7 29.0 24.4 19.4 21.5 20.2 43.8 21.4 19.6 21.2 30.9 23.1 23.4 27.0 26.7 20.3 26.5 28.4 20.3 20.3 47.5 22.0 20.6 18.5 19.5 22.1 31.3 25.9 35.1 33.4 41.2 22.3 27.0 38.1 19.4 22.3 24.5 22.2 18.9 22.1 20.7 25.4 24.3 23.2 18.2 21.5 45.4 44.3 50.0 21.5 25.9 35.4 32.6 15.5 11.5 9.8 11.2 12.9 23.9 12.3 16.7 23.7 18.6 47.7 17.1 14.6 27.4 15.6 21.3 14.6 18.3 18.9 26.7 20.7 22.5 22.0 10.4 26.1 16.8 21.8 18.6 17.5 24.3 16.6 20.3 11.2 16.8 23.2 12.5 13.6 19.4 35.4 41.6 53.4 30.9 27.4 15.9 18.4 22.5 26.5 22.1 27.3 11.6 16.5 14.6 47.2 30.0 14.7 48.5 41.4 9.8 8.8 19.2 18.2 31.2 27.4 18.5 33.6 16.9 22.2 10.5 27.6 50.0 44.3 19.0 35.4 21.7 21.5 21.6 22.1 45.4 19.9 25.9 21.1 14.5 21.5 26.2 27.0 24.4 35.4 26.2 30.1 22.1 29.6 23.1 23.4 28.4 20.3 19.5 18.9 20.8 26.1 28.3 47.3 27.0 33.9 33.9 20.4 18.7 15.9 29.6 29.5 49.5 99.5 41.8 15.3 30.4 28.2 0.0 73.6 40.6 37.9 39.4 69.2 28.2 68.8 31.8 32.4 30.1 52.8 7.4 26.7 58.0 40.5 60.5 36.5 35.7 49.3 35.1 25.5 71.7 38.7 6.5 49.1 43.3 46.0 26.2 35.2 38.5 49.1 46.1 PARN DAN ENSG00000140694 "Poly(A)-specific ribonuclease" O95453 16 14435701-14632728 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006314, CAB011673, HPA012010" Supported Supported "Nuclear speckles" NA NA "Nuclear speckles" "CAB011673: AB_778216, HPA006314: AB_1079567, HPA012010: AB_1854976" "unprognostic (2.54e-1)" "unprognostic (3.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.99e-3)" "unprognostic (5.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (2.46e-1)" "unprognostic (3.10e-3)" "unprognostic (1.09e-2)" 19.4 25.9 14.9 23.5 19.1 12.5 19.8 16.8 23.5 21.3 21.0 22.7 23.3 14.4 24.6 29.0 19.0 19.4 22.5 18.4 15.4 19.0 17.9 18.9 26.7 31.6 22.2 17.9 21.8 22.7 37.4 26.0 21.9 21.0 21.4 21.8 21.0 18.9 31.0 19.2 21.0 18.8 28.7 18.3 20.1 19.6 25.4 19.6 29.4 27.8 14.0 26.8 25.6 19.3 16.1 15.6 13.3 14.8 15.0 17.8 11.0 11.9 14.1 7.4 9.4 12.4 14.3 8.6 10.2 14.3 12.7 12.2 7.8 11.1 21.4 25.9 11.7 9.6 13.0 17.1 11.5 17.6 18.1 10.1 14.7 9.8 17.4 13.0 17.4 14.6 12.9 14.4 11.4 16.3 9.6 8.5 11.9 12.5 12.1 12.3 14.8 17.5 11.3 10.1 9.4 8.5 23.2 16.8 21.5 8.6 8.4 9.3 6.7 20.8 11.3 14.1 10.8 11.9 10.1 7.8 12.4 6.5 6.7 10.4 12.3 13.1 26.1 13.6 12.8 13.6 11.9 11.1 13.3 13.5 14.8 13.9 16.1 13.1 15.5 15.6 13.9 17.8 17.8 7.2 15.0 14.3 10.8 14.7 11.0 14.9 19.1 16.8 23.5 15.4 19.0 22.2 17.9 21.0 19.6 29.8 30.8 16.1 7.2 6.4 12.1 17.3 10.2 29.4 14.8 10.4 7.9 25.3 10.0 12.5 8.9 13.5 10.5 0.0 11.2 19.3 10.4 6.8 2.3 9.9 12.9 7.9 14.3 12.3 13.1 5.8 19.5 11.7 10.1 28.9 14.8 10.0 12.3 12.2 16.6 8.4 9.1 19.4 9.2 30.7 62.8 7.2 18.8 11.3 12.5 3.9 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390415-96434143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6" "Cell type enriched" "Detected in some" 39 "Intestinal endocrine cells: 215.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "basophil: 1.8" "Lineage enhanced" "Detected in single" "granulocytes: 1.8" "Group enriched" "Detected in some" 5 "SCLC-21H: 19.0;U-138 MG: 16.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" NA NA "HPA048564: AB_2680444, HPA079656: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavorable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 2.3 8.5 1.3 6.0 10.1 0.5 1.3 0.5 36.6 1.2 3.3 0.5 0.0 6.7 0.5 8.8 0.4 0.4 0.6 1.0 2.8 27.1 0.5 0.4 0.8 0.4 3.1 14.0 0.6 9.8 0.3 10.9 0.4 7.5 0.5 3.3 0.1 2.8 0.5 0.5 1.7 4.6 1.0 1.3 0.5 8.4 0.5 0.4 0.0 1.9 0.0 0.3 0.9 0.6 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.0 0.0 0.0 1.7 0.9 0.3 0.1 0.1 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 2.7 0.0 0.0 0.4 0.0 0.0 1.0 16.1 0.5 0.2 0.1 0.0 0.0 0.1 13.4 0.0 0.3 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 10.1 0.5 36.6 2.8 27.1 3.1 14.0 7.5 0.4 0.0 0.0 0.0 0.1 0.0 5.5 0.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 215.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.1 2.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.0;thyroid gland: 79.5" "Cell type enhanced" "Detected in many" 26 "Horizontal cells: 125.5;Melanocytes: 199.1;Muller glia cells: 518.9" "Group enriched" "Detected in many" 6 "pancreatic cancer: 14.6;thyroid cancer: 65.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Group enriched" "Detected in some" 5 "AF22: 36.7;SCLC-21H: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 1.6 35.0 16.3 1.7 20.5 1.3 1.3 7.7 27.8 2.9 4.2 1.6 0.0 6.2 0.9 1.2 2.1 2.0 1.4 3.1 18.0 11.1 1.1 1.0 2.2 0.8 4.1 16.2 11.6 23.7 0.9 1.7 1.5 9.0 1.3 2.8 16.6 2.7 2.3 1.0 16.6 3.3 1.3 5.4 0.9 11.9 4.7 3.8 0.0 79.5 0.0 0.9 1.9 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 36.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 20.5 7.7 27.8 18.0 11.1 4.1 16.2 9.0 3.8 0.0 5.3 0.0 0.0 7.2 27.6 0.9 0.0 0.0 1.2 0.0 5.9 0.0 0.0 0.0 76.9 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 125.5 0.0 8.0 0.0 2.7 2.6 0.2 199.1 0.0 0.0 518.9 4.6 0.0 0.0 0.0 11.5 0.0 1.0 0.5 0.2 1.3 0.0 0.0 0.0 0.1 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165986603 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.8" "Cell type enhanced" "Detected in many" 7 "Horizontal cells: 15.9;Muller glia cells: 21.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 7.7;LHCN-M2: 14.0;RH-30: 8.2;RT4: 8.5;SH-SY5Y: 8.6;TIME: 14.5;U-2 OS: 7.9" "Region enriched" "Detected in many" 11 "basal ganglia: 307.0" "Group enriched" "Detected in all" 4 "basal ganglia: 155.2;cerebellum: 80.7" "CAB045998, HPA047200" Supported NA NA "CAB045998: AB_2162589, HPA047200: AB_2679981" "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 3.1 1.9 1.7 1.0 36.8 0.0 3.4 4.5 6.9 2.2 1.0 1.1 4.3 0.8 2.9 7.5 0.7 3.1 3.2 3.6 2.6 2.1 8.8 0.9 4.3 1.4 2.7 1.1 3.4 0.8 1.2 2.5 5.3 1.7 2.6 0.5 0.6 0.7 4.9 0.9 0.6 0.8 4.3 1.1 2.5 1.2 8.7 16.0 0.0 12.2 1.0 0.8 7.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 6.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.8 0.0 0.0 0.0 5.0 0.0 2.8 0.0 0.0 0.0 3.4 0.0 7.7 0.0 0.5 0.0 0.0 0.1 0.0 0.6 0.0 0.0 7.5 0.0 0.0 0.0 14.0 0.1 1.1 0.0 1.5 0.0 5.6 1.7 8.2 0.0 7.4 8.5 2.2 8.6 0.0 0.0 0.4 0.6 0.0 0.0 14.5 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 36.8 4.5 6.9 2.6 2.1 2.7 1.1 1.7 16.0 0.0 0.0 0.0 2.8 0.3 8.8 6.9 0.0 1.4 1.2 5.2 2.0 6.0 3.3 1.7 8.9 10.3 0.0 0.0 0.0 5.2 2.0 11.7 1.1 0.0 0.7 15.9 0.0 9.8 0.0 11.8 0.0 0.0 1.7 0.0 0.0 21.0 0.2 0.0 0.4 6.5 0.6 0.0 2.1 6.6 0.5 0.3 2.4 0.0 0.0 2.2 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623252-178072755 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.8;fHDF/TERT166: 5.6;HAP1: 3.2;Hep G2: 6.4" HPA034560 Approved "Intracellular and membrane" NA NA "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.9 0.5 1.3 0.7 1.0 0.2 2.5 0.2 0.8 4.2 3.1 0.1 0.0 1.2 1.9 1.5 0.3 0.4 5.4 2.6 1.6 2.0 4.0 11.8 0.5 0.0 3.3 0.0 0.5 7.8 9.8 13.6 0.0 1.2 20.8 0.5 5.6 8.5 1.2 7.5 0.3 7.6 1.7 5.6 0.1 0.4 3.8 0.0 0.1 13.2 0.7 0.1 0.6 0.3 1.0 0.8 2.2 0.9 0.9 0.7 0.2 0.1 1.0 0.5 0.2 0.2 0.0 0.2 2.5 0.4 0.1 0.9 0.5 3.8 0.1 1.6 5.6 0.6 0.2 3.2 0.1 0.1 0.0 2.0 2.4 0.2 6.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.1 0.4 0.6 0.9 0.3 1.3 0.1 0.7 0.5 0.1 0.5 0.0 1.1 0.1 0.7 1.7 0.0 0.2 0.4 0.5 0.3 0.0 0.0 0.3 0.6 0.2 0.3 0.5 0.0 0.0 1.0 0.1 0.2 1.6 0.7 1.1 0.7 0.6 0.5 0.7 0.6 0.7 0.4 1.0 0.6 0.7 2.2 0.9 0.9 0.8 0.7 0.2 1.3 1.0 0.2 0.7 1.6 2.0 3.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 PDE12 "2'-PDE, 3635, DKFZp667B1218" ENSG00000174840 "Phosphodiesterase 12" Q6L8Q7 3 57556276-57566844 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043171 Approved NA NA "HPA043171: AB_10794654" "unprognostic (2.79e-1)" "unprognostic (3.18e-1)" "prognostic favorable (2.85e-5)" "unprognostic (2.39e-1)" "unprognostic (1.48e-1)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (8.43e-3)" "unprognostic (1.27e-1)" "unprognostic (6.45e-2)" "unprognostic (2.10e-1)" "unprognostic (9.88e-3)" "prognostic favorable (3.63e-8)" "unprognostic (6.97e-3)" "unprognostic (1.32e-1)" "unprognostic (7.85e-2)" "unprognostic (2.62e-1)" 14.2 22.1 10.0 13.7 15.7 21.1 11.2 18.0 18.4 10.7 12.4 16.9 10.6 15.7 14.9 8.5 19.8 10.9 12.7 11.2 11.0 10.8 16.8 22.1 11.4 14.3 15.5 10.6 15.7 17.0 18.2 15.5 12.7 13.6 11.8 12.2 13.2 14.6 12.4 19.1 11.4 13.8 12.2 12.4 12.6 13.8 9.9 14.2 21.7 13.0 11.7 16.4 14.1 11.6 10.4 10.1 16.6 12.6 14.5 13.4 9.5 12.9 12.8 8.0 14.9 10.4 7.4 14.6 11.0 10.6 12.4 11.2 16.9 8.9 21.3 4.4 9.9 16.6 8.6 17.0 11.5 10.3 9.7 8.9 16.0 11.2 12.9 11.9 20.7 16.6 10.1 7.9 15.0 13.3 6.5 10.7 11.2 13.2 15.7 11.2 10.0 18.5 6.8 12.4 10.2 22.1 7.0 6.5 15.8 10.0 15.1 7.1 11.5 11.9 14.0 11.9 6.8 10.6 12.0 13.1 10.4 9.9 19.7 17.8 15.4 22.3 18.8 12.2 16.3 15.3 16.6 9.1 8.2 11.6 12.6 12.9 7.2 10.9 11.9 10.1 10.4 13.4 13.4 2.6 14.5 12.5 5.4 12.9 9.5 10.0 15.7 18.0 18.4 11.0 10.8 15.5 10.6 13.6 14.2 23.8 18.7 12.8 16.2 32.6 18.3 9.7 17.8 2.7 13.6 29.6 11.8 16.3 5.0 8.9 1.0 11.8 13.4 23.3 8.4 9.0 11.5 15.3 19.6 24.1 12.9 25.4 12.0 18.4 14.0 1.1 9.8 12.5 11.8 8.2 9.9 17.8 7.8 12.9 11.7 13.5 24.8 6.5 10.3 13.4 8.7 34.6 17.2 13.8 14.9 16.5 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 66.0;kidney: 37.1" "Group enriched" "Detected in many" 6 "Distal tubular cells: 157.5;Early spermatids: 314.8;Late spermatids: 455.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "ASC diff: 22.8;HHSteC: 13.5;HSkMC: 28.9" "Group enriched" "Detected in many" 6 "amygdala: 118.0;basal ganglia: 76.2;cerebral cortex: 161.5;hippocampal formation: 155.8;hypothalamus: 47.8" "Low region specificity" "Detected in all" HPA022151 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 7.6 3.9 13.8 3.6 11.5 0.5 4.1 66.0 25.3 11.5 8.8 6.2 1.7 2.6 7.3 6.7 4.7 7.4 18.2 11.8 12.6 4.1 37.1 3.2 3.1 1.8 7.1 15.7 9.2 2.0 1.3 2.3 1.3 6.9 3.8 5.6 3.0 1.8 4.8 2.4 2.1 4.6 11.8 10.1 2.6 4.6 24.6 9.0 0.0 35.1 2.6 1.1 8.3 9.0 0.0 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.1 2.3 0.0 22.8 1.9 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 3.2 0.0 13.5 0.0 0.0 28.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 3.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 13.8 11.5 66.0 25.3 12.6 4.1 7.1 15.7 6.9 9.0 0.0 1.6 0.0 2.2 1.1 12.6 3.6 0.0 0.0 2.3 26.2 0.0 0.1 157.5 0.3 314.8 5.8 0.0 0.0 0.3 0.0 1.9 2.0 0.0 0.0 0.1 0.0 0.0 8.0 0.0 455.7 13.8 0.2 0.0 0.0 0.6 0.2 0.2 0.0 7.8 1.4 1.1 51.8 47.4 4.4 3.9 1.1 0.0 0.0 0.0 0.7 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549350-54579239 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 52.6" "Cell type enhanced" "Detected in many" 11 "Erythroid cells: 23.3;Kupffer cells: 11.5;Sertoli cells: 12.9;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 52.6" "Cell type enriched" "Detected in single" 4 "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 4 "T-cells: 1.6" "Cell line enhanced" "Detected in some" "HDLM-2: 11.5;HL-60: 6.4;HMC-1: 12.3;NB-4: 8.1;THP-1: 7.8;U-937: 6.5" "Region enriched" "Detected in all" 6 "basal ganglia: 895.2" "Region enriched" "Detected in all" 7 "basal ganglia: 253.8" HPA018492 Enhanced NA NA "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 12.3 1.4 9.9 4.6 52.6 5.6 2.7 3.1 19.4 2.6 3.7 1.4 0.0 1.2 3.9 2.5 1.7 2.4 2.9 1.9 3.7 3.8 1.3 1.6 2.9 1.6 3.0 9.3 12.5 0.6 11.0 0.5 0.5 5.8 1.0 1.7 0.5 1.3 2.1 0.7 1.0 2.6 4.9 1.2 4.8 2.5 1.1 7.7 0.0 2.7 0.0 1.1 2.8 1.1 0.2 0.3 0.1 0.3 0.1 1.6 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 11.5 0.3 4.7 0.0 0.0 0.0 6.4 12.3 0.7 0.0 0.0 0.0 0.0 0.0 4.6 0.0 1.9 0.0 0.0 0.7 8.1 3.4 0.0 0.0 2.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 7.8 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.4 0.0 6.5 1.3 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.2 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.4 9.9 52.6 3.1 19.4 3.7 3.8 3.0 9.3 5.8 7.7 0.0 0.6 0.0 0.2 0.9 0.1 3.1 0.0 0.0 1.2 3.5 0.0 0.0 0.0 0.0 4.8 0.3 0.0 23.3 0.0 0.0 0.4 0.3 0.0 0.0 7.3 4.8 1.7 0.0 11.5 3.4 2.0 5.2 0.0 1.8 0.0 0.0 0.0 0.0 2.8 0.0 0.1 12.9 9.5 0.9 0.5 0.4 0.2 1.5 0.0 0.1 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32299329 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.6;heart muscle: 56.2" "Group enriched" "Detected in some" 7 "Bipolar cells: 55.0;Cardiomyocytes: 112.6;Cone photoreceptor cells: 49.1;Early spermatids: 40.4;Late spermatids: 38.3" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 15.2;fHDF/TERT166: 49.0;hTERT-RPE1: 15.0;U-251 MG: 26.5;WM-115: 35.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.9 2.7 10.6 3.2 27.7 0.9 5.1 2.4 17.1 1.2 2.7 30.1 0.0 2.3 3.1 6.8 7.4 8.4 2.4 56.2 14.8 7.5 4.0 1.0 5.0 1.4 31.1 12.0 4.9 2.7 1.3 1.3 4.0 16.3 2.9 2.7 7.9 2.6 4.2 1.4 0.9 2.8 10.4 17.1 1.4 3.8 4.2 33.6 0.0 3.9 0.2 1.0 7.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 0.0 0.2 0.1 0.0 15.2 6.2 7.2 5.9 0.0 0.0 0.0 0.0 49.0 0.0 0.4 0.0 0.0 9.3 0.0 0.0 0.4 0.4 0.0 0.0 0.0 10.9 0.6 0.0 1.5 0.1 15.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 7.4 0.0 2.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 8.1 3.0 0.1 26.5 0.0 0.0 0.0 0.7 0.1 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 27.7 2.4 17.1 14.8 7.5 31.1 12.0 16.3 33.6 0.0 0.0 0.0 0.8 0.0 55.0 112.6 0.0 4.0 1.2 1.8 49.1 0.0 0.0 5.6 40.4 2.9 0.0 0.0 0.4 0.0 0.0 0.2 8.1 0.0 0.1 3.2 0.0 0.0 0.0 38.3 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.4 0.0 4.4 0.0 2.1 1.1 0.7 0.0 0.0 0.0 0.0 0.0 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.0;lymphoid tissue: 65.4" "Group enriched" "Detected in some" 6 "Endothelial cells: 33.1;Intestinal endocrine cells: 33.1;Ito cells: 118.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 30.4;basal ganglia: 34.2;cerebral cortex: 48.0;hippocampal formation: 18.0;olfactory region: 27.0" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.7;T-cells: 9.6" "Cell line enriched" "Detected in some" 8 "HeLa: 107.5" "Group enriched" "Detected in all" 5 "amygdala: 111.5;basal ganglia: 166.3;cerebral cortex: 98.9;hippocampal formation: 120.9" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 27.8 18.4 30.4 3.0 34.2 2.5 25.4 1.0 48.0 8.9 7.7 3.8 1.9 3.5 9.4 4.9 10.2 11.6 12.0 11.3 18.0 6.1 7.0 10.4 5.1 3.8 3.8 27.0 3.4 2.4 4.4 3.4 6.6 6.7 4.8 5.2 3.0 2.3 6.3 6.6 4.8 4.2 10.3 2.1 65.4 4.2 2.9 7.4 0.1 7.0 3.9 2.2 8.3 11.2 3.7 1.2 0.2 1.0 0.1 9.6 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 2.6 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 107.5 0.1 0.2 0.0 1.6 0.0 0.2 0.5 4.4 0.2 2.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.0 2.9 0.0 0.0 0.2 0.0 0.0 9.6 0.5 0.0 0.0 0.4 0.1 0.0 0.0 13.7 0.0 2.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.8 0.0 9.6 1.0 5.6 3.7 5.7 5.6 1.2 2.5 3.7 3.0 0.2 0.1 0.5 0.0 2.3 1.9 30.4 34.2 1.0 48.0 18.0 6.1 3.8 27.0 6.7 7.4 0.0 0.3 0.0 0.0 2.3 2.7 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 33.1 0.0 0.0 0.0 0.2 0.9 0.1 1.1 0.9 0.5 1.6 33.1 118.4 10.0 1.5 0.3 1.0 1.7 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.4 0.0 4.3 1.4 0.8 2.5 0.0 0.0 0.0 0.3 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20369245-20684381 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.2" "Cell type enhanced" "Detected in many" 15 "Bipolar cells: 41.0;Cardiomyocytes: 107.8;Horizontal cells: 49.3;Smooth muscle cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;HEL: 14.6;HeLa: 39.5;HUVEC TERT2: 7.1;SH-SY5Y: 14.8;U-138 MG: 11.4" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 35.4" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 23000 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 7.1 1.0 1.7 4.7 2.0 0.0 3.8 3.5 1.4 7.8 15.9 1.0 2.0 2.1 7.8 3.5 9.1 4.9 5.5 62.2 1.6 1.4 3.7 1.8 3.9 3.3 1.9 1.1 7.1 6.5 1.0 2.8 13.8 2.7 6.3 9.0 12.0 7.8 4.2 2.0 1.4 21.4 6.0 1.8 2.1 5.5 2.3 0.7 0.0 2.8 1.9 0.9 4.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 7.9 0.0 1.8 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.6 39.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.1 0.0 0.0 0.0 2.2 0.0 0.1 14.8 0.0 0.0 0.0 3.5 0.0 0.0 0.2 11.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.7 2.0 3.5 1.4 1.6 1.4 1.9 1.1 2.7 0.7 0.0 0.0 0.0 0.1 0.2 41.0 107.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 3.7 0.2 2.2 24.6 0.0 0.4 0.0 3.5 0.5 16.2 0.0 0.5 49.3 4.1 0.6 0.0 0.0 1.4 0.0 1.7 0.0 7.4 2.5 0.5 24.6 0.7 2.6 2.2 6.5 51.8 0.2 0.4 0.3 0.0 0.0 13.9 0.2 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643723-14872044 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 42.6" "Cell type enhanced" "Detected in many" 7 "granulocytes: 34.7;Hepatocytes: 50.5;Spermatocytes: 45.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 19.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 5.0;T-cells: 8.7" "Cell line enhanced" "Detected in many" "HL-60: 13.6;Karpas-707: 15.7;THP-1: 16.7;U-266/70: 17.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA056111: AB_2683041" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favorable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 42.6 1.0 2.3 12.6 2.2 6.7 17.0 19.2 3.0 2.9 21.8 0.9 0.8 2.2 0.9 1.4 2.6 1.0 6.9 4.7 2.2 2.1 2.4 18.2 10.2 14.1 1.6 1.6 0.9 7.3 0.3 5.1 5.5 1.5 10.7 8.1 1.9 16.5 1.3 0.8 0.9 6.3 9.7 2.1 8.7 3.0 12.5 0.8 7.8 1.2 2.3 7.1 10.5 4.5 0.3 0.4 5.0 1.2 0.1 8.7 1.8 0.0 1.5 3.4 5.5 6.8 0.0 1.3 0.4 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 1.6 0.0 5.1 0.0 0.0 0.1 11.3 0.1 8.3 10.2 2.4 13.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 4.0 11.9 15.7 0.0 0.1 2.7 6.6 4.6 1.8 2.5 6.5 1.5 10.3 0.0 1.1 5.2 9.7 1.3 8.8 3.0 1.6 0.0 16.7 0.0 0.0 0.8 0.0 0.0 17.7 5.4 0.4 0.1 2.3 1.0 0.0 0.7 2.9 1.4 0.7 2.9 0.3 4.2 3.2 0.4 0.2 8.7 7.5 5.0 0.1 1.2 0.1 4.2 1.8 2.3 2.2 19.2 3.0 2.2 2.1 1.6 1.6 1.5 0.8 14.9 9.9 1.9 0.8 0.2 0.4 8.2 0.0 6.7 11.4 1.8 0.0 1.0 1.7 0.0 12.4 2.2 2.6 23.3 4.3 1.9 8.5 3.4 34.7 50.5 6.3 0.0 1.2 7.4 14.0 10.1 1.4 12.3 0.0 1.0 13.1 4.5 2.9 17.5 8.5 1.9 0.3 0.0 0.1 45.1 11.1 0.1 2.1 11.7 9.7 0.9 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469631 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 31.8" "Cell type enhanced" "Detected in many" 13 "Late spermatids: 164.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 22.0;NB-4: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 6.4 2.5 9.0 4.2 13.9 3.4 6.3 15.0 38.5 8.4 4.3 3.2 0.4 2.0 4.4 1.1 3.1 4.8 5.0 4.1 12.4 6.9 2.8 1.9 7.7 2.0 5.3 19.4 1.7 9.8 17.3 2.3 4.9 34.7 3.7 3.0 3.1 7.1 4.0 26.1 2.2 2.7 4.7 3.6 4.1 6.1 31.8 4.5 0.0 5.4 1.0 1.9 4.6 3.5 0.2 3.3 5.9 4.4 5.3 2.0 1.3 0.0 1.4 0.3 3.9 11.6 6.9 2.2 3.3 6.6 0.4 1.1 3.5 3.2 1.5 9.7 8.5 0.2 0.3 2.3 0.4 0.2 3.8 3.3 13.6 4.7 3.8 7.5 2.2 22.0 5.1 0.4 3.7 0.0 0.4 3.1 1.2 10.7 3.3 2.3 1.0 1.3 25.3 1.8 3.9 2.8 8.9 2.2 11.7 0.6 0.8 2.5 0.9 0.2 0.1 3.6 0.6 0.5 4.5 6.6 5.0 6.5 3.4 2.1 6.5 0.5 7.2 2.1 0.1 4.0 5.9 2.6 5.1 1.5 4.4 0.8 0.2 0.5 2.0 3.3 0.1 0.1 0.7 0.2 5.3 4.4 0.2 1.2 1.3 9.0 13.9 15.0 38.5 12.4 6.9 5.3 19.4 34.7 4.5 3.0 15.2 8.0 2.7 9.0 23.9 5.8 12.7 10.7 7.9 8.7 0.0 0.3 0.0 2.8 44.2 10.9 1.3 0.0 11.1 4.3 13.4 3.1 32.2 0.8 9.8 52.4 0.0 11.6 18.3 164.4 16.1 37.2 13.5 14.4 6.2 1.3 10.6 0.0 17.0 0.0 2.6 6.5 8.1 7.7 7.8 7.0 0.3 16.0 6.8 1.4 PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.2" "Cell type enhanced" "Detected in many" 7 "Glandular cells: 81.5;Horizontal cells: 108.1;monocytes: 104.6" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 36.6" "Group enriched" "Detected in all" 5 "B-cells: 16.1;granulocytes: 36.6;T-cells: 13.3" "Cell line enhanced" "Detected in many" "AN3-CA: 24.4;HUVEC TERT2: 36.6;NTERA-2: 22.2;SK-MEL-30: 22.0;TIME: 20.4;U-266/84: 19.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003005 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Golgi apparatus" Cytosol "HPA003005: AB_1079587" "unprognostic (7.86e-2)" "unprognostic (3.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.90e-1)" "unprognostic (3.21e-1)" "unprognostic (3.33e-3)" "unprognostic (1.35e-1)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (6.10e-2)" "unprognostic (8.78e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (5.04e-4)" "unprognostic (2.89e-2)" "unprognostic (3.54e-1)" "unprognostic (9.04e-3)" "unprognostic (8.33e-3)" 14.9 2.9 21.5 28.4 29.0 48.2 15.0 12.7 31.9 6.4 6.6 39.2 0.7 3.9 6.7 2.1 3.9 3.5 8.1 16.1 20.7 18.8 3.7 8.7 10.0 15.9 36.3 14.2 2.0 1.7 1.7 3.4 13.1 32.2 18.3 8.6 6.6 15.9 10.3 28.2 6.2 8.5 9.5 37.4 18.5 4.2 3.2 36.9 2.3 5.5 5.5 14.7 16.1 3.9 16.1 2.6 36.6 2.8 4.4 13.3 3.7 0.1 7.0 13.8 24.4 0.7 0.7 0.0 4.5 5.3 4.2 5.6 0.0 0.0 2.0 0.1 8.4 0.1 0.0 0.1 0.0 4.2 5.9 0.0 0.1 2.0 0.0 0.5 4.9 0.0 1.4 0.2 2.1 0.1 0.6 36.6 0.0 0.0 1.3 1.8 0.1 0.0 2.8 22.2 0.0 0.3 1.0 2.4 1.3 3.4 0.0 0.1 10.6 0.0 1.2 22.0 1.2 0.1 1.7 20.4 3.3 0.8 1.8 0.7 0.6 19.1 7.5 3.4 5.1 1.4 2.7 2.8 8.4 4.4 2.4 8.4 15.4 8.3 6.2 2.4 16.1 9.4 6.5 36.6 4.4 2.1 2.6 13.3 3.7 21.5 29.0 12.7 24.6 20.7 18.8 36.3 14.2 32.2 36.9 8.9 16.4 50.2 24.5 18.0 35.4 29.1 0.0 2.7 12.5 5.2 0.0 5.2 0.0 0.5 7.9 23.2 0.0 0.0 0.8 1.6 9.3 81.5 14.0 1.6 12.6 108.1 4.1 12.3 25.8 5.6 0.3 42.5 49.0 104.6 1.2 12.2 0.1 0.0 2.5 1.6 3.3 0.0 10.3 0.1 0.7 7.0 4.7 36.2 1.1 5.7 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 28.6" "Cell type enhanced" "Detected in many" 14 "Enterocytes: 141.8;Paneth cells: 179.9;Undifferentiated cells: 66.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 6.0;Hep G2: 4.0;U-87 MG: 9.0" "HPA048975, HPA054218" Approved Approved "Midbody ring,Centrosome,Cytosol" NA NA "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 2.0 1.3 1.8 1.5 2.8 1.0 2.0 0.8 6.1 4.1 4.4 1.5 3.1 1.5 6.4 6.8 1.3 4.2 5.6 4.2 1.6 1.9 4.1 2.0 4.1 0.5 1.7 5.1 2.0 0.8 0.3 3.5 7.0 2.8 5.8 1.3 2.5 1.3 5.4 13.4 0.6 4.1 3.4 0.7 2.3 5.2 2.6 1.1 0.4 1.2 28.6 0.7 1.8 3.3 1.3 0.6 3.5 0.7 1.0 0.7 0.2 0.1 0.3 0.2 0.3 0.1 0.3 6.0 0.1 0.0 0.2 0.3 1.2 0.2 0.2 0.6 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.4 4.0 0.2 0.2 0.6 0.7 0.1 2.6 0.0 0.5 0.0 0.3 0.9 2.1 0.1 0.4 0.2 0.3 0.2 0.4 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.8 0.3 0.5 0.0 1.6 0.5 0.3 0.0 0.4 0.2 0.7 0.1 1.3 0.6 0.2 9.0 0.2 0.3 3.4 0.7 1.0 0.6 0.4 0.5 0.5 0.5 0.4 0.2 1.3 0.5 0.7 3.5 1.0 0.4 0.6 0.3 0.2 1.8 2.8 0.8 6.1 1.6 1.9 1.7 5.1 2.8 1.1 3.0 8.8 0.0 2.2 4.8 3.0 28.1 5.1 0.0 1.2 0.0 5.9 1.9 0.0 0.0 29.1 3.6 141.8 0.0 0.0 3.5 4.2 1.8 4.6 0.0 0.4 0.0 6.9 1.3 2.2 26.0 0.6 1.1 1.7 0.0 34.4 2.7 0.0 179.9 3.9 0.0 3.3 45.3 13.4 1.9 1.9 3.3 0.9 0.0 66.4 18.4 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.0" "Cell type enhanced" "Detected in many" 4 "Alveolar cells type 2: 76.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "eosinophil: 28.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 28.1" "Cell line enhanced" "Detected in many" "A549: 25.3;AN3-CA: 29.1;HeLa: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favorable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.2 1.9 4.4 6.8 8.6 46.2 5.3 4.2 13.0 13.5 18.6 1.4 14.7 4.1 17.1 14.0 10.3 6.6 12.7 15.5 4.5 5.8 12.8 3.4 11.1 3.7 5.2 6.6 5.3 2.9 7.0 9.0 11.8 2.7 18.2 11.2 8.6 24.4 16.5 60.0 5.1 7.5 35.8 5.0 3.8 10.2 2.6 2.8 4.4 6.2 11.3 9.5 20.0 11.2 6.1 0.7 28.1 1.1 0.1 0.8 0.5 0.0 25.3 5.3 29.1 1.0 1.9 4.2 0.6 0.7 1.4 2.1 9.9 0.8 1.9 0.1 0.2 4.3 4.3 0.0 1.1 2.5 1.1 2.9 3.7 41.9 2.1 3.9 1.7 0.2 3.9 0.9 4.0 0.7 0.4 3.0 0.1 0.0 0.6 2.4 1.8 1.4 4.1 1.0 0.7 1.3 0.4 6.7 4.2 6.6 9.5 0.9 3.3 6.7 11.3 5.7 5.0 0.8 3.7 3.4 0.3 0.1 5.0 1.3 1.4 0.0 0.2 4.3 7.0 1.1 2.0 1.1 28.1 0.8 0.0 0.8 6.1 0.7 0.3 0.7 6.1 0.5 0.4 1.5 0.1 0.1 0.0 0.4 0.5 4.4 8.6 4.2 13.0 4.5 5.8 5.2 6.6 2.7 2.8 29.8 76.9 9.1 30.5 9.4 13.6 32.7 10.2 22.7 48.9 40.1 68.7 9.2 10.0 0.5 16.6 12.4 16.7 0.0 1.6 14.8 13.1 46.1 21.9 0.8 4.3 1.6 32.0 14.1 6.0 29.3 1.4 9.4 10.1 4.6 18.4 16.1 5.4 10.5 4.6 17.7 52.1 0.0 5.3 0.5 7.1 7.8 2.6 37.3 10.1 21.1 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494395-119628991 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 11 "Peritubular cells: 98.6;Smooth muscle cells: 79.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.6;HHSteC: 35.4;hTERT-RPE1: 12.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 3100000 Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 12.3 4.9 2.0 28.2 2.3 0.4 8.1 3.0 2.3 21.3 28.0 1.7 20.1 6.5 17.3 21.4 30.7 10.7 13.3 5.3 2.0 2.8 3.8 1.2 11.4 4.1 2.4 3.4 10.0 7.8 5.1 3.4 8.9 4.4 31.8 11.7 20.2 8.5 23.7 6.8 4.2 15.6 45.6 2.0 2.1 9.1 7.6 1.2 0.9 9.1 8.1 2.2 25.9 15.9 1.5 0.5 1.4 0.4 0.6 2.1 4.2 8.1 0.4 5.7 0.6 2.0 3.0 1.0 5.5 24.6 0.2 0.5 0.5 0.7 0.8 0.2 6.8 1.5 3.0 1.8 0.8 0.7 0.2 3.7 9.1 1.4 0.4 35.4 1.9 0.9 3.3 1.7 0.6 0.0 12.9 0.7 1.9 1.0 1.5 0.8 0.4 2.4 0.3 1.2 0.9 1.4 0.3 2.9 2.1 2.1 2.5 2.2 4.6 6.3 8.0 0.6 4.4 1.4 1.0 1.2 3.2 2.8 1.7 0.7 2.1 1.0 0.7 3.1 0.5 0.4 0.0 0.3 0.0 0.6 0.1 2.1 1.5 1.3 0.4 0.2 1.0 0.6 0.9 1.4 0.6 0.4 0.5 0.4 4.2 2.0 2.3 3.0 2.3 2.0 2.8 2.4 3.4 4.4 1.2 6.0 4.6 0.0 2.3 3.1 8.1 3.5 12.7 1.4 5.7 1.8 13.7 0.2 0.0 12.0 25.6 3.3 6.3 0.0 2.5 0.2 3.8 2.4 1.1 1.0 0.2 4.8 2.4 1.3 0.0 9.4 19.2 0.7 5.0 0.0 10.1 28.4 4.2 9.1 98.6 0.5 5.9 19.4 79.9 2.9 5.5 2.0 0.2 0.0 8.6 1.6 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857955-149944793 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 153.4" "Cell type enriched" "Detected in many" 12 "Rod photoreceptor cells: 2864.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "CACO-2: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced NA NA "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.2 2.3 0.2 0.2 0.2 0.9 0.2 0.3 0.2 0.2 1.8 0.2 0.3 0.2 0.2 20.1 2.4 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 4.6 0.2 0.2 0.2 1.0 153.4 1.4 0.2 0.2 1.6 0.2 0.2 0.2 0.2 0.1 3.1 0.2 0.2 0.4 0.3 0.5 0.2 0.2 1.5 0.8 3.3 0.8 1.2 0.8 0.1 0.4 0.8 0.6 0.6 0.3 0.3 0.6 0.3 0.1 0.4 0.1 7.6 0.8 0.9 1.4 0.2 1.4 0.7 0.2 0.4 0.5 0.6 0.3 1.0 1.1 0.6 0.2 0.8 0.6 0.3 1.1 0.9 0.6 0.6 0.2 0.4 0.3 1.4 1.5 0.4 0.5 0.9 0.5 0.2 0.5 0.3 0.8 0.7 0.5 1.0 0.8 1.1 0.0 0.7 0.2 0.6 1.0 0.5 1.4 0.8 1.7 0.8 0.5 0.6 0.4 0.5 0.8 0.8 0.6 3.3 0.8 0.5 0.6 0.4 0.5 0.7 0.6 0.5 0.2 1.5 0.7 0.8 2.8 1.2 0.5 0.8 0.4 0.1 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 7.2 0.0 0.5 1.0 117.9 3.6 0.0 5.3 4.5 0.0 229.7 0.9 0.0 0.0 7.0 0.6 3.9 0.0 0.2 1.9 0.6 0.3 3.5 0.8 0.3 71.5 0.0 2.5 0.3 4.0 1.1 0.5 0.0 1.0 0.2 162.2 0.1 2.9 0.4 0.0 2864.0 0.0 1.0 1.1 0.9 0.5 2.4 0.5 0.9 0.1 PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625584-670782 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease mutation, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2;retina: 64.2" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 453.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 8.0;JURKAT: 11.8;MOLT-4: 20.5;REH: 11.1;SCLC-21H: 14.0;SH-SY5Y: 8.2;U-266/84: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol NA NA Cytosol "HPA054148: AB_2682401, HPA059929: AB_2684166" "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favorable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" 1.6 1.9 12.1 4.6 19.1 6.7 3.8 2.3 13.2 2.3 1.3 30.2 1.5 0.8 2.5 3.9 1.4 9.6 3.2 5.2 18.1 10.2 4.6 0.7 4.2 12.0 29.6 9.8 2.6 1.4 9.1 3.2 2.6 14.5 2.5 1.0 64.2 3.5 2.9 0.7 1.8 2.2 2.1 20.2 8.7 2.5 3.6 22.4 4.3 11.4 0.2 8.3 4.1 1.1 16.5 14.1 11.2 5.8 10.2 13.1 7.1 0.0 0.2 0.8 0.4 0.2 0.3 0.2 0.0 0.0 0.5 1.4 0.0 0.1 0.2 8.0 0.2 0.7 0.1 1.7 0.4 0.0 0.1 0.0 0.6 0.2 0.0 4.1 0.1 0.3 0.5 0.1 2.4 0.0 0.5 0.7 11.8 0.1 0.6 0.0 0.2 20.5 0.2 6.5 0.4 0.2 11.1 0.2 0.4 1.4 0.9 14.0 8.2 0.0 0.3 0.1 3.3 0.4 0.0 0.2 0.1 0.8 0.1 0.3 5.4 15.2 0.2 0.2 0.2 0.1 11.2 4.2 0.6 11.5 5.8 10.5 10.0 7.7 7.9 6.6 16.5 12.2 13.1 1.1 10.2 5.6 14.1 11.4 7.1 12.1 19.1 2.3 10.0 18.1 10.2 29.6 9.8 14.5 22.4 3.0 5.3 4.5 1.2 0.3 18.2 3.7 0.0 16.0 5.7 0.0 78.5 0.1 1.7 5.1 0.4 1.8 0.0 0.0 0.6 0.2 0.8 0.9 3.5 0.0 9.2 11.1 1.7 2.5 3.9 0.0 1.4 3.4 3.3 7.2 0.2 20.9 0.7 0.0 1.4 6.7 453.5 0.0 0.2 3.9 2.7 0.3 0.2 7.0 0.1 0.6 PDE6C "ACHM5, COD4, PDEA2" ENSG00000095464 "Phosphodiesterase 6C" P51160 10 93612588-93666010 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 12.8" "Cell type enriched" "Detected in some" 18 "Cone photoreceptor cells: 53.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (1.39e-3)" "unprognostic (7.41e-3)" "unprognostic (2.61e-2)" "unprognostic (2.24e-1)" "unprognostic (3.17e-2)" "unprognostic (5.23e-3)" "unprognostic (2.46e-3)" "unprognostic (2.81e-3)" "unprognostic (9.68e-2)" "unprognostic (2.64e-1)" "unprognostic (1.51e-2)" "unprognostic (2.96e-3)" "unprognostic (2.19e-7)" "unprognostic (1.19e-1)" "unprognostic (6.61e-2)" "unprognostic (1.81e-1)" "unprognostic (1.80e-3)" 0.4 0.6 0.3 0.4 0.4 1.3 0.4 3.0 0.7 0.8 0.3 0.3 0.3 0.4 0.5 0.3 0.3 0.5 0.3 0.3 0.3 0.2 0.3 0.5 0.5 1.0 0.3 0.3 1.0 0.3 0.0 0.8 0.3 0.3 0.7 0.0 12.8 0.8 0.3 3.1 3.1 0.7 0.3 0.3 0.9 0.6 0.7 0.3 0.3 0.6 0.3 0.3 0.4 0.7 0.2 0.1 0.2 0.2 0.3 0.6 0.0 0.2 0.7 0.4 1.4 0.0 0.1 1.0 0.8 0.0 0.0 0.0 0.8 1.0 0.6 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.6 0.5 1.4 2.4 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.3 0.8 0.0 0.2 1.0 1.6 0.8 0.1 0.4 0.6 0.0 0.1 0.0 0.2 1.2 0.1 0.2 0.0 0.1 0.5 0.5 0.3 0.2 0.0 0.4 0.0 0.2 0.7 0.6 0.6 0.6 0.4 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.6 0.5 0.2 0.3 0.2 0.1 0.0 0.0 0.3 0.4 3.0 0.3 0.3 0.2 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 260.3" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 2889.5" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 29.7;NK-cell: 57.8" "Group enriched" "Detected in all" 5 "granulocytes: 29.7;NK-cells: 57.8" "Cell line enhanced" "Detected in some" "Hep G2: 6.3;NB-4: 6.7;NTERA-2: 11.6;REH: 13.5;SuSa: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles NA NA Vesicles "HPA045118: AB_2732517" "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 0.9 1.3 0.4 2.9 0.5 4.7 0.7 0.5 0.6 0.4 0.8 0.5 0.4 0.0 0.4 0.5 0.6 0.3 1.6 0.5 0.5 0.7 3.8 2.6 2.0 13.8 0.6 0.5 0.5 0.4 0.0 0.5 8.6 0.5 0.5 0.5 260.3 0.5 0.4 0.6 0.8 2.8 0.4 0.8 17.9 0.7 2.2 0.5 2.5 0.6 0.4 4.6 2.1 0.4 1.3 8.6 29.7 7.7 57.8 2.4 3.7 0.2 0.3 0.5 0.0 0.3 0.0 0.0 0.3 1.1 1.2 1.3 0.1 0.8 0.6 0.2 0.7 0.6 0.1 0.2 0.2 2.8 0.2 0.0 0.9 0.1 6.3 0.9 0.1 0.2 0.0 0.2 1.2 0.0 2.4 3.3 0.4 0.1 0.3 1.3 0.8 0.1 6.7 11.6 0.0 0.4 13.5 0.1 2.0 0.0 0.0 0.1 0.3 0.0 0.3 0.5 8.6 0.1 0.8 1.3 0.4 0.1 0.2 0.3 0.1 0.6 1.0 1.6 2.7 0.2 29.7 5.1 8.6 1.2 7.7 0.4 0.8 0.3 0.6 8.6 1.3 0.7 2.4 0.7 57.8 4.2 0.8 0.0 3.7 0.4 0.5 0.5 0.6 0.5 0.7 0.6 0.5 0.5 0.5 0.0 1.1 1.4 0.0 0.8 338.0 0.0 0.0 0.0 0.0 5.2 486.9 0.2 1.7 0.4 0.6 0.0 0.0 0.0 0.2 0.3 0.2 0.1 24.1 0.0 18.8 247.9 0.0 3.1 3.8 1.6 0.0 3.2 3.3 19.8 0.0 402.2 0.3 0.0 0.0 0.3 2889.5 0.0 0.0 0.7 0.2 1.3 0.2 2.1 0.0 0.0 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973022-14981865 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 67.4" "Cell type enriched" "Detected in some" 6 "Cone photoreceptor cells: 783.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.2;JURKAT: 1.0;MOLT-4: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles NA NA Vesicles "HPA045118: AB_2732517" "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.1 1.3 1.2 0.2 1.5 9.4 0.1 0.1 4.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 1.0 2.1 0.1 0.1 0.2 0.2 2.2 0.1 0.1 0.1 0.0 0.1 2.5 0.7 0.1 0.1 67.4 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.8 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.6 0.7 0.0 0.0 1.4 0.2 0.0 0.8 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 1.2 1.5 0.1 4.2 1.0 2.1 2.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 47.5 0.0 0.0 0.0 0.0 0.0 783.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 1.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.0 0.0 0.0 0.0 0.0 141.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 PDE7A HCP1 ENSG00000205268 "Phosphodiesterase 7A" Q13946 8 65717510-65842322 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 87.5;skeletal muscle: 48.3" "Cell type enhanced" "Detected in many" 5 "B-cells: 80.1;Rod photoreceptor cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 32.0;MOLT-4: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018770, HPA027340" Approved NA NA "CAB018770: AB_677329, HPA027340: AB_1855127" "unprognostic (2.76e-1)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (1.17e-2)" "unprognostic (2.15e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (1.44e-2)" "unprognostic (6.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.35e-4)" "unprognostic (3.08e-2)" "unprognostic (1.26e-1)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" 6.9 1.4 4.4 22.7 4.6 12.3 10.0 7.3 4.3 7.1 4.1 5.8 5.9 5.6 3.6 8.2 3.6 3.8 6.1 21.0 4.3 3.6 13.4 2.7 10.1 27.7 4.3 2.7 3.4 9.2 1.4 7.5 4.0 4.6 7.3 5.0 3.3 11.7 12.6 48.3 4.3 13.6 4.0 3.4 16.3 6.2 4.8 5.5 87.5 13.0 25.4 22.4 5.4 4.7 7.7 2.2 5.3 0.7 2.1 12.6 1.8 4.0 3.6 15.8 7.4 2.3 2.0 6.7 3.0 2.6 3.8 3.7 4.4 2.7 11.4 0.7 1.9 3.4 4.5 5.8 6.4 4.1 13.3 3.0 8.2 5.7 3.1 1.1 6.5 3.3 2.9 10.8 2.5 7.6 3.3 3.8 27.9 6.1 32.0 2.6 2.3 53.3 8.2 16.8 3.2 1.6 19.9 2.4 2.9 2.6 8.1 7.9 9.0 3.2 1.6 1.6 11.4 8.7 17.1 2.4 5.4 6.7 3.8 2.4 15.6 6.7 19.8 5.5 13.9 2.9 0.2 0.7 5.3 3.7 0.6 6.0 6.7 5.7 3.7 1.5 7.7 12.6 9.6 2.6 2.1 0.1 2.2 4.5 1.8 4.4 4.6 7.3 4.3 4.3 3.6 4.3 2.7 4.6 5.5 17.9 17.7 80.1 11.5 16.1 26.4 35.0 17.8 26.8 25.0 3.5 53.0 11.4 0.0 6.7 20.3 9.0 4.2 0.0 4.6 7.2 18.3 16.5 9.2 3.9 9.2 17.5 9.2 8.0 14.5 10.3 6.9 15.6 15.1 10.0 6.4 11.4 5.1 5.8 7.1 15.4 69.6 0.0 10.3 10.0 11.5 16.4 7.2 50.7 6.0 8.1 PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851696-136195574 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 10 "Collecting duct cells: 21.0;Endothelial cells: 18.2;Ito cells: 35.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 7.3;ASC TERT1: 8.6;EFO-21: 13.4;HeLa: 7.8;HSkMC: 18.7;HUVEC TERT2: 8.7;U-2197: 9.3" "Region enriched" "Detected in all" 5 "basal ganglia: 112.3" "Low region specificity" "Detected in all" HPA023967 Uncertain Approved Nucleoplasm No NA Nucleoplasm "HPA023967: AB_1855128" "unprognostic (3.18e-1)" "unprognostic (3.47e-1)" "unprognostic (2.34e-1)" "unprognostic (1.79e-3)" "unprognostic (3.34e-1)" "unprognostic (3.22e-4)" "unprognostic (1.37e-2)" "unprognostic (3.00e-1)" "unprognostic (2.80e-1)" "unprognostic (6.73e-3)" "unprognostic (1.11e-2)" "unprognostic (7.85e-2)" "prognostic favorable (1.59e-4)" "unprognostic (3.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (3.34e-2)" 5.8 4.3 7.3 4.0 21.9 0.8 3.6 1.6 12.8 6.2 4.0 2.3 25.2 3.6 14.2 4.9 2.8 4.2 6.1 7.9 5.1 7.4 9.6 6.4 3.3 2.8 6.4 4.2 22.7 1.6 3.7 8.7 2.2 5.9 6.8 5.0 5.4 5.0 28.5 7.2 1.5 3.7 13.5 5.3 2.3 5.2 2.9 7.1 7.7 8.3 6.1 1.9 10.6 5.1 4.3 2.6 0.6 0.9 0.7 1.8 0.3 0.0 4.5 0.1 0.0 7.3 8.6 0.0 0.4 2.3 1.7 0.9 0.0 0.0 0.0 13.4 2.9 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 7.8 0.0 3.1 0.1 0.0 18.7 0.0 3.4 0.0 0.7 8.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.0 0.5 3.2 3.0 0.1 0.1 0.0 0.0 1.5 0.0 1.9 0.0 9.3 0.0 0.1 0.0 0.0 0.5 0.0 0.7 0.2 0.9 0.6 0.2 0.2 0.1 1.5 0.4 0.2 2.6 4.3 1.8 1.0 0.3 0.7 0.1 0.2 0.2 0.3 7.3 21.9 1.6 12.8 5.1 7.4 6.4 4.2 5.9 7.1 0.0 0.3 3.0 0.2 0.3 2.3 8.5 2.5 0.0 0.0 21.0 0.0 0.1 0.0 0.1 0.4 18.2 0.0 0.0 1.5 0.0 3.3 0.3 10.3 4.7 0.3 6.4 7.0 35.0 1.5 0.0 11.2 0.5 0.0 0.0 0.0 13.8 0.1 0.0 7.4 1.2 0.7 12.9 3.1 0.1 0.2 1.3 0.0 0.0 0.0 0.1 PDE8A HsT19550 ENSG00000073417 "Phosphodiesterase 8A" O60658 15 84980440-85139145 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RT4: 40.2" "Low region specificity" "Detected in all" HPA007722 Approved Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA007722: AB_1855130" "unprognostic (1.68e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.97e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.94e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (8.99e-3)" "unprognostic (2.75e-2)" "unprognostic (3.42e-1)" "unprognostic (3.72e-1)" "unprognostic (4.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.94e-2)" 14.3 16.6 14.0 8.5 18.7 2.6 9.8 2.6 14.8 11.4 21.0 35.5 9.1 13.2 9.0 8.2 5.9 8.8 14.3 7.8 17.2 9.8 21.7 26.2 10.5 5.4 23.3 12.1 12.0 12.7 17.6 7.1 10.1 20.1 6.9 19.8 12.6 8.2 9.2 5.6 6.2 11.7 10.7 17.6 6.7 10.8 10.6 25.5 2.2 11.2 4.8 5.0 11.9 10.6 1.3 1.7 1.7 4.5 0.6 3.2 0.6 12.8 21.5 3.7 2.5 15.5 8.2 4.4 8.6 9.6 7.7 8.9 4.8 7.7 2.5 6.8 11.6 9.2 9.1 15.6 6.8 10.4 4.7 9.3 3.4 13.9 6.9 11.2 2.0 5.2 8.2 4.2 9.0 8.7 6.7 9.9 2.9 6.8 8.4 7.0 10.8 1.1 1.9 1.7 4.2 4.0 1.5 3.0 3.6 6.1 40.2 8.5 6.5 8.5 9.4 25.0 4.2 3.0 3.9 7.7 18.1 6.3 6.4 14.1 4.1 7.2 2.8 12.3 8.1 5.1 0.0 2.4 1.7 1.1 2.2 2.1 0.8 1.8 1.9 1.7 1.3 2.2 0.9 0.2 0.6 4.5 0.0 3.2 0.6 14.0 18.7 2.6 14.8 17.2 9.8 23.3 12.1 20.1 25.5 6.0 31.1 9.3 10.7 10.1 13.4 5.2 30.6 10.7 15.9 7.0 11.8 6.3 6.6 8.7 5.6 17.9 20.8 0.0 8.2 5.8 13.3 17.2 20.9 20.8 9.7 9.5 13.9 16.5 12.5 4.1 10.0 16.1 10.1 6.4 17.5 2.5 11.6 31.7 10.6 15.7 32.2 38.8 14.1 22.4 14.5 9.2 3.8 4.8 22.9 22.5 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77429807 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "thyroid gland: 67.7" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 26.4;Cone photoreceptor cells: 51.1;Glandular cells: 41.8;Horizontal cells: 65.2;Muller glia cells: 77.6" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "BJ hTERT+: 12.4;HeLa: 28.4;SK-BR-3: 7.6" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA036911: AB_2675378, HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 6.8 2.5 9.9 0.7 14.2 0.4 3.8 1.1 16.3 6.3 1.2 2.3 0.3 1.2 11.3 3.2 1.1 10.1 2.1 7.9 8.2 9.2 3.1 1.2 2.2 0.7 5.4 8.3 1.9 4.2 0.3 3.8 13.1 8.6 10.5 0.8 2.0 5.3 7.1 0.4 0.7 1.3 10.3 2.3 0.4 1.5 1.5 5.7 0.3 67.7 0.3 0.7 0.8 1.4 0.2 0.8 1.4 2.3 0.4 0.4 0.1 0.3 3.4 1.4 0.4 1.2 0.0 0.5 1.1 12.4 0.2 0.1 1.4 0.2 0.5 0.2 0.1 0.3 0.9 0.1 0.0 0.2 0.2 1.1 0.7 28.4 0.3 0.0 0.5 0.6 0.5 0.0 0.0 0.0 0.6 0.0 0.6 0.2 0.3 0.0 0.2 0.6 0.7 0.8 0.3 0.1 0.8 1.4 0.7 0.0 0.3 3.8 1.1 1.7 7.6 0.8 1.1 1.6 1.1 0.6 0.4 0.2 0.2 0.6 0.9 0.5 0.6 1.6 0.7 0.4 0.0 0.3 1.4 0.3 2.2 0.1 0.2 0.2 0.3 0.8 0.2 0.4 0.0 0.3 0.4 2.3 0.5 0.1 0.1 9.9 14.2 1.1 16.3 8.2 9.2 5.4 8.3 8.6 5.7 3.0 3.2 0.0 1.6 0.3 11.8 26.4 0.0 0.0 2.3 1.8 51.1 0.0 0.0 1.8 3.6 0.7 0.0 0.0 0.0 0.0 2.3 41.8 1.1 0.0 0.3 65.2 4.7 4.3 0.6 3.0 5.5 0.0 1.7 0.0 0.6 77.6 0.2 0.0 0.0 0.8 4.6 6.5 8.2 0.6 2.1 1.0 0.0 0.0 0.5 2.4 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653636-42775509 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 15 "Enterocytes: 168.7;Paneth cells: 77.2" "Cancer enhanced" "Detected in all" "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 4 "NK-cells: 1.7;T-cells: 6.8" "Cell line enhanced" "Detected in many" "AF22: 16.3;EFO-21: 16.5;MCF7: 12.2;NB-4: 18.2;NTERA-2: 22.5;SCLC-21H: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 6.1 6.6 9.9 6.8 15.2 0.8 9.4 13.7 9.0 3.7 37.1 11.9 14.0 3.0 5.7 18.8 6.1 10.3 7.7 3.5 6.2 7.7 13.2 2.5 4.7 4.6 10.0 4.9 4.1 4.0 4.7 6.0 9.6 6.9 33.2 15.8 9.7 8.8 15.9 2.3 3.8 26.1 22.3 8.0 15.9 8.4 1.5 8.9 4.9 5.2 2.1 4.1 12.6 4.0 0.5 0.9 1.0 0.1 1.7 6.8 0.5 0.0 1.5 16.3 2.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.8 9.8 0.0 16.5 0.0 1.1 0.0 1.4 5.3 0.0 0.0 5.6 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 12.2 0.8 18.2 22.5 8.0 0.0 0.0 0.0 0.6 11.2 4.5 12.5 7.4 2.8 0.0 0.2 4.0 0.1 10.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.1 0.6 0.2 0.5 6.8 1.7 1.0 1.7 0.1 0.9 2.2 0.5 9.9 15.2 13.7 6.7 6.2 7.7 10.0 4.9 6.9 8.9 3.0 5.3 0.0 8.5 0.9 21.0 1.4 5.1 1.4 0.0 17.4 0.0 0.0 24.9 6.2 0.3 6.7 168.7 0.0 2.1 0.1 3.1 27.6 1.1 0.8 5.6 33.4 12.6 3.7 0.6 1.7 10.9 1.0 27.0 1.8 19.3 9.4 5.1 77.2 5.6 7.6 2.7 12.9 5.9 0.4 0.7 0.5 0.3 2.1 22.2 13.1 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69328621-69330595 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Cell type enhanced" "Detected in single" 21 "Alveolar cells type 1: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No Mitochondria Nucleoplasm "HPA063409: AB_2685007" "unprognostic (4.28e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favorable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 6.6 7.9 4.8 7.8 4.5 5.3 4.8 3.1 6.9 3.6 7.6 3.8 3.3 7.1 5.3 5.6 8.4 4.4 6.5 3.8 4.6 3.3 14.9 30.2 3.7 7.0 3.0 5.2 5.0 14.2 8.2 3.9 4.9 4.4 5.3 4.1 4.3 12.8 4.6 10.4 6.0 5.2 3.4 2.3 5.0 8.3 3.7 2.0 10.2 7.3 9.2 6.2 3.7 4.0 10.3 3.2 2.5 2.8 1.7 6.9 1.5 9.0 6.1 1.2 2.9 1.8 1.4 10.7 7.6 2.0 5.4 4.7 15.0 6.4 16.7 10.1 2.6 2.5 13.0 3.7 4.0 2.2 4.0 31.0 8.5 5.8 21.4 3.7 11.8 6.8 2.8 7.1 4.8 2.3 0.9 3.1 8.6 20.3 1.9 2.9 11.6 9.2 12.4 7.8 3.3 11.2 21.7 1.9 15.5 4.3 5.7 10.4 8.3 13.1 2.3 6.4 0.5 12.9 3.8 4.7 4.7 8.8 5.4 8.7 15.8 10.5 19.7 3.1 8.8 6.0 0.0 2.8 2.5 1.2 1.6 3.1 4.3 3.9 3.9 3.0 10.3 6.9 2.5 0.0 1.7 1.5 3.2 3.0 1.5 4.8 4.5 3.1 6.9 4.6 3.3 3.0 5.2 4.4 2.0 3.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926066 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.2" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 71.4;Early spermatids: 99.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 38.9;cerebral cortex: 62.2;olfactory region: 32.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 39.5;hTERT-RPE1: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 5.1 32.3 11.0 4.6 38.9 5.9 7.9 7.5 62.2 7.5 4.3 4.7 1.6 3.3 7.7 8.6 8.0 6.1 9.6 22.9 10.1 8.0 6.3 2.2 6.0 5.6 5.1 32.5 9.7 9.3 20.6 4.2 6.6 4.4 5.2 6.2 4.4 6.6 4.7 31.8 3.2 5.5 5.5 3.4 5.8 5.5 12.9 4.8 4.1 9.3 7.0 5.8 7.7 5.1 11.0 12.7 7.8 21.5 2.8 19.5 8.8 7.9 3.9 8.6 3.6 7.1 13.1 2.8 6.3 7.0 7.4 8.7 4.1 29.6 4.4 21.2 10.0 39.5 17.7 3.6 5.3 11.0 0.4 1.8 2.1 4.9 1.4 8.2 1.0 3.0 8.4 10.5 12.6 20.2 39.3 16.7 4.0 0.7 7.3 9.0 1.9 6.2 3.2 3.9 8.6 5.1 1.5 5.1 0.8 5.1 5.5 0.8 3.7 4.1 0.4 19.3 7.3 1.3 1.2 29.6 9.0 5.8 21.0 7.4 4.1 1.7 3.7 11.5 3.7 7.9 3.1 15.4 7.8 5.6 14.3 5.3 9.3 9.1 7.2 12.7 11.0 5.5 4.8 1.8 2.8 21.5 2.1 19.5 8.8 11.0 38.9 7.5 62.2 10.1 8.0 5.1 32.5 4.4 4.8 11.9 5.6 13.4 11.2 11.6 34.7 71.4 22.9 22.7 17.0 15.7 7.9 3.5 5.0 24.3 99.2 14.7 6.0 0.0 11.9 3.2 11.6 13.3 5.8 2.5 5.7 9.5 9.8 14.1 20.8 22.0 10.6 16.2 10.1 2.8 5.2 19.0 22.2 7.0 12.7 8.6 10.6 6.5 12.7 7.2 9.7 9.5 3.7 10.1 8.9 17.0 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA Mitochondria "HPA019950: AB_1855156, HPA062059: AB_2684671" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favorable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 10.7 7.2 7.4 3.7 10.5 3.2 8.7 11.5 16.5 4.9 7.5 10.1 5.7 10.4 7.9 7.2 8.9 7.2 6.0 4.8 7.4 7.1 18.1 16.5 8.6 5.0 9.0 9.4 14.9 13.8 12.0 7.0 7.7 16.0 7.8 8.4 8.5 7.1 6.9 6.3 4.7 6.2 4.6 6.3 4.0 6.7 8.6 8.9 4.6 18.0 4.0 5.9 6.3 5.5 3.3 1.3 1.8 0.4 6.1 6.3 2.0 7.2 8.9 5.5 10.8 14.9 7.7 6.9 3.8 14.8 8.9 13.4 18.1 5.2 10.2 5.5 5.3 8.5 9.3 16.0 8.6 8.6 2.4 8.1 5.1 4.5 11.8 8.1 6.5 9.0 5.8 6.5 12.6 13.1 9.7 3.8 11.5 9.8 7.3 7.9 4.8 12.6 4.7 6.5 4.9 11.3 12.5 7.7 16.0 4.7 7.8 11.1 6.3 12.3 5.0 4.6 4.5 6.7 3.2 3.5 5.4 7.4 3.3 5.6 13.0 12.0 10.1 7.5 5.2 5.4 1.3 0.4 1.8 6.3 0.3 5.2 1.8 3.1 5.1 1.3 3.3 4.5 5.0 1.3 6.1 0.2 0.8 0.9 2.0 7.4 10.5 11.5 16.5 7.4 7.1 9.0 9.4 16.0 8.9 8.9 18.5 5.9 4.3 4.6 7.9 4.5 7.6 1.4 4.5 8.7 13.7 9.1 6.6 2.7 0.1 1.8 5.1 0.0 2.5 1.6 4.2 6.7 5.8 11.5 2.1 4.8 3.5 6.7 0.6 1.9 2.8 0.8 3.3 0.0 4.0 8.4 2.8 5.8 4.2 8.1 6.3 0.0 3.1 4.4 1.3 2.0 3.0 1.9 5.8 7.0 PDXP "CIN, dJ37E16.5, FLJ32703" ENSG00000241360 "Pyridoxal phosphatase" Q96GD0 22 37658727-37666934 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.4;liver: 34.7" "Cell type enhanced" "Detected in some" 13 "Alveolar cells type 2: 1.1;Enterocytes: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 8 "plasmacytoid DC: 12.9" "Lineage enriched" "Detected in many" 8 "dendritic cells: 12.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000531 Approved NA NA 17000 "HPA000531: AB_2666018" "unprognostic (6.29e-2)" "unprognostic (7.89e-3)" "unprognostic (1.00e-1)" "unprognostic (2.89e-1)" "unprognostic (2.15e-2)" "unprognostic (3.25e-2)" "unprognostic (2.81e-1)" "unprognostic (4.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-3)" "unprognostic (2.76e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-3)" "unprognostic (2.04e-1)" "unprognostic (4.66e-2)" "unprognostic (2.38e-1)" 2.4 14.8 43.5 1.7 32.0 3.0 2.5 24.9 55.4 1.7 8.3 5.3 0.8 15.4 3.7 4.1 1.0 3.4 2.7 12.9 38.1 27.7 10.2 34.7 1.3 3.9 16.4 15.8 3.5 8.4 6.1 7.9 1.0 13.6 3.3 7.6 3.8 7.1 4.2 5.7 0.9 15.8 4.8 9.1 2.6 3.3 10.4 4.6 4.2 3.4 1.0 5.4 2.2 0.7 1.5 12.9 0.5 0.4 0.8 0.9 0.1 2.8 6.8 14.1 12.4 4.5 1.1 1.7 6.6 3.1 12.1 9.5 2.6 0.3 18.4 6.8 3.3 10.4 1.4 19.1 0.1 10.4 5.6 37.9 3.1 9.7 13.8 2.9 12.6 15.5 0.4 1.2 5.9 8.7 4.7 5.6 21.8 11.2 11.1 10.8 2.4 25.7 21.0 7.2 4.2 16.7 20.0 10.2 13.5 5.3 0.3 33.0 20.8 6.4 5.4 11.7 6.4 1.3 10.0 3.3 10.5 13.1 11.1 13.3 11.5 14.6 19.6 9.9 4.0 13.2 0.0 0.3 0.5 0.9 0.4 0.1 1.5 0.3 0.6 0.6 1.4 0.3 0.1 0.4 0.8 0.2 12.9 0.3 0.1 43.5 32.0 24.9 50.6 38.1 27.7 16.4 15.8 13.6 4.6 0.0 1.1 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 PEPD ENSG00000124299 "Peptidase D" P12955 19 33386950-33521794 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Collagen degradation" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 92.9;kidney: 106.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1020.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015599, HPA072045" Enhanced Approved Nucleoplasm NA NA 1000000000 Nucleoplasm "HPA015599: AB_1855192, HPA072045: AB_2732194" "unprognostic (1.39e-1)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (4.01e-2)" "unprognostic (2.98e-1)" "unprognostic (6.77e-2)" "unprognostic (2.82e-1)" "unprognostic (3.64e-2)" "unprognostic (3.96e-1)" "unprognostic (5.10e-2)" "unprognostic (1.11e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.50e-9)" "unprognostic (4.38e-2)" "unprognostic (1.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" 23.5 17.2 9.8 8.9 10.4 4.1 21.8 7.6 14.9 9.8 60.1 18.7 6.9 58.1 14.3 11.5 14.9 9.6 13.6 8.0 10.8 9.1 106.0 48.6 11.1 10.6 16.0 7.7 12.6 9.0 9.6 12.5 10.4 13.0 9.2 6.6 13.3 9.6 9.0 9.7 11.4 92.9 10.4 17.4 13.4 9.3 8.4 11.5 8.4 15.0 9.7 10.6 11.9 11.9 17.1 32.3 27.5 39.1 16.8 25.8 32.6 13.3 36.3 10.7 17.3 45.7 17.6 24.8 11.9 24.4 15.2 17.3 31.6 11.8 5.4 17.8 29.8 11.7 3.5 15.4 9.7 12.5 15.4 15.2 34.7 7.4 32.1 31.3 10.1 42.1 21.7 9.2 13.8 8.6 11.2 20.3 10.7 6.6 15.8 16.5 16.3 7.7 3.4 14.7 26.6 14.8 15.2 14.6 15.0 13.1 35.3 13.2 33.8 22.2 11.0 17.9 9.4 7.6 11.0 16.9 14.7 15.9 19.0 13.7 14.5 21.5 4.8 15.7 14.6 20.9 27.5 36.1 2.5 25.8 39.1 22.6 17.1 25.7 23.8 32.3 16.3 16.9 19.6 1.9 16.8 27.2 9.9 23.6 32.6 9.8 10.4 7.6 14.9 10.8 9.1 16.0 7.7 13.0 11.5 20.8 24.3 20.2 26.1 17.2 33.9 11.7 43.3 26.8 11.4 69.8 3.9 19.3 167.5 63.4 7.6 44.9 37.6 0.0 38.3 59.7 34.6 21.4 55.5 161.7 189.6 58.8 16.6 35.0 46.9 8.9 45.8 63.2 64.1 131.7 14.5 69.3 37.3 28.5 57.0 1020.8 23.8 38.8 38.8 11.4 48.3 17.8 25.4 31.0 16.7 18.0 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 24.2;liver: 24.4;skeletal muscle: 48.3" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 15.5" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "MAIT T-cell: 2.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "ASC diff: 13.9;Hep G2: 5.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 24.2 0.2 0.1 1.6 0.1 0.1 13.1 0.1 0.2 0.1 1.7 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.4 24.4 0.1 1.6 0.1 0.1 0.1 0.6 0.2 0.2 0.1 0.1 0.3 0.2 0.1 1.3 0.1 48.3 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.5 8.3 0.6 0.2 2.0 1.5 0.1 0.0 0.7 1.3 2.1 0.3 0.3 0.2 0.4 0.6 13.9 0.3 1.0 0.0 0.1 0.2 0.0 0.9 0.2 0.6 0.3 0.1 0.6 0.5 0.1 0.3 0.5 0.4 1.1 0.4 0.1 5.5 0.0 0.1 0.6 0.2 0.6 0.1 0.4 0.0 0.0 1.3 0.1 2.2 0.2 0.7 0.6 0.3 0.4 0.4 0.3 0.5 0.2 0.2 0.0 0.4 0.4 0.3 0.5 1.6 0.2 1.2 0.4 0.0 0.2 0.1 0.5 0.4 0.2 1.1 1.7 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.2 0.7 2.1 1.5 0.2 0.0 0.0 0.8 0.0 0.8 0.0 1.3 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.5 0.1 0.0 0.0 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 70.2;Late spermatids: 128.8;Rod photoreceptor cells: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 13.9;plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 8 "dendritic cells: 16.7;granulocytes: 13.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA049975: AB_2680977, HPA063575: AB_2685046" "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favorable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (1.86e-2)" 3.3 6.1 9.8 5.8 16.6 15.7 5.1 2.1 14.6 7.3 16.0 19.5 5.3 23.2 4.0 9.1 7.7 4.5 9.1 22.8 14.1 7.7 22.0 3.6 10.9 5.3 13.4 15.1 4.3 11.9 6.2 27.5 3.0 25.3 3.9 18.1 22.4 6.3 3.5 34.9 6.4 18.7 4.0 17.4 12.5 10.7 6.1 15.1 6.5 38.4 8.8 5.0 3.4 3.6 1.6 16.7 13.9 1.9 1.1 0.4 0.4 9.7 4.3 2.8 4.9 5.9 2.9 4.7 1.4 1.7 2.4 1.3 10.5 14.1 1.7 2.2 2.2 7.4 13.9 2.1 5.2 1.4 0.3 2.1 13.8 10.8 3.9 4.9 0.0 9.7 4.1 8.0 2.3 13.2 2.9 0.5 5.8 9.4 0.1 1.3 2.9 2.3 0.4 3.9 4.7 6.5 0.0 0.0 0.2 3.3 10.1 4.5 2.7 9.1 15.4 11.4 3.2 10.6 1.1 0.2 0.0 5.3 7.5 1.3 4.5 4.4 0.9 6.1 0.0 2.6 1.0 0.9 13.9 0.2 1.9 0.3 1.3 0.1 0.3 0.8 1.6 0.3 0.4 2.6 1.1 1.3 16.7 0.0 0.4 9.8 16.6 2.1 14.6 14.1 7.7 13.4 15.1 25.3 15.1 6.0 42.0 4.5 3.4 13.5 7.3 70.2 5.1 14.7 5.7 15.7 0.0 0.5 21.6 4.0 47.4 2.7 43.0 0.0 6.7 0.4 2.5 6.5 9.2 4.9 4.9 3.2 5.8 1.3 11.3 128.8 2.6 6.0 20.3 1.8 18.9 8.1 10.5 27.7 2.8 30.6 111.9 0.0 3.2 3.1 3.3 10.2 1.3 1.0 27.6 11.2 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.6;skeletal muscle: 135.7" "Cell type enhanced" "Detected in many" 8 "Collecting duct cells: 184.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 20.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 72.7;RPTEC TERT1: 45.9;T-47d: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: AB_2678717" "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 105.6 9.0 16.4 25.7 17.9 77.0 43.4 8.5 29.4 6.6 8.8 29.1 10.6 7.4 9.4 6.3 13.0 14.4 22.4 5.7 16.6 13.2 22.1 11.2 15.1 12.1 19.2 12.9 8.0 8.1 4.0 10.2 7.5 20.7 5.4 3.8 19.3 9.1 20.0 135.7 11.8 6.9 6.5 36.0 12.4 6.7 4.6 16.8 3.3 2.9 4.7 10.3 10.3 10.1 1.5 3.6 20.5 7.1 0.8 4.7 2.9 5.2 72.7 5.8 4.7 21.9 2.7 3.0 7.7 5.5 5.8 9.0 3.4 19.3 9.0 5.1 3.3 4.5 17.0 6.2 12.3 6.7 10.7 4.3 5.3 3.7 1.2 1.8 5.1 8.1 1.9 4.1 9.9 2.4 14.8 11.1 6.3 3.9 3.4 4.6 8.6 3.6 4.8 5.6 7.5 5.1 8.2 2.8 3.5 45.9 2.7 5.5 2.2 5.6 6.2 11.0 10.4 47.8 6.1 14.0 6.1 5.6 0.7 9.3 7.0 2.4 8.1 16.7 6.0 9.2 2.2 5.6 5.5 1.8 7.1 4.7 1.5 3.4 2.3 3.6 1.4 2.5 2.4 20.5 0.8 4.1 2.2 3.2 2.9 16.4 17.9 8.5 16.9 16.6 13.2 19.2 12.9 20.7 16.8 71.5 75.9 13.7 14.3 91.1 7.8 17.3 15.3 13.4 42.1 184.9 49.1 0.2 0.0 42.7 5.1 29.2 7.4 0.0 22.5 4.6 29.8 4.3 41.7 11.6 19.4 6.4 8.2 9.2 79.2 6.1 2.6 37.7 43.9 23.4 5.2 0.4 46.2 5.8 6.7 2.4 1.6 0.0 21.1 0.7 1.6 55.8 0.8 21.3 5.4 9.9 PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.0" "Cell type enhanced" "Detected in many" 13 "Extravillous trophoblasts: 36.2;Mucus-secreting cells: 11.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.5;eosinophil: 11.4;intermediate monocyte: 7.3;neutrophil: 21.6;non-classical monocyte: 12.2" "Group enriched" "Detected in many" 6 "granulocytes: 21.6;monocytes: 12.2" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 22.9;U-87 MG: 36.5;WM-115: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli NA NA Nucleoli "HPA047719: AB_2680129, HPA066058: AB_2685606" "unprognostic (7.60e-2)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" 2.0 2.2 4.0 3.9 4.9 12.7 2.1 6.3 6.3 2.6 17.1 8.6 3.0 17.8 2.1 18.5 6.4 1.5 1.8 1.4 4.2 5.2 3.6 1.7 3.8 6.3 7.4 2.7 3.5 18.9 4.1 5.1 9.5 6.9 3.3 3.5 3.3 2.5 2.0 4.8 3.3 24.0 2.5 5.3 10.0 1.2 26.0 5.2 0.4 1.6 3.6 2.6 4.9 4.2 0.2 2.7 21.6 12.2 0.2 0.5 2.1 5.0 1.5 3.6 3.3 1.2 1.8 7.1 2.5 4.3 5.2 12.6 2.5 1.8 2.2 2.4 1.9 12.4 1.4 1.5 4.4 4.6 1.5 1.2 5.1 3.3 2.7 1.0 0.9 2.3 1.8 6.6 8.3 0.8 22.9 1.2 2.9 1.7 1.9 4.1 1.1 0.3 7.1 2.2 1.0 3.4 0.4 1.7 2.3 2.0 4.7 1.0 2.2 2.7 1.2 9.9 3.7 2.8 2.2 0.3 5.3 2.1 0.6 15.3 8.8 1.9 1.3 36.5 1.8 31.7 0.0 6.5 11.4 0.2 7.3 0.1 0.2 0.3 0.0 2.7 0.1 0.5 0.1 21.6 0.2 12.2 0.3 0.0 2.1 4.0 4.9 6.3 6.3 4.2 5.2 7.4 2.7 6.9 5.2 0.0 2.2 0.0 0.3 2.9 5.0 0.6 0.0 1.4 1.2 0.0 2.0 11.1 0.0 2.0 2.6 0.4 1.7 0.0 1.3 36.2 1.5 0.4 1.1 0.0 5.3 6.4 4.1 1.8 11.0 2.0 0.9 4.4 1.7 0.0 11.8 3.6 2.9 0.3 0.7 0.0 4.3 0.0 0.8 0.5 0.5 1.5 4.6 0.0 1.5 0.0 PGA3 ENSG00000229859 "Pepsinogen 3, group I (pepsinogen A)" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "stomach 1: 1048.8" "Group enriched" "Detected in some" 5 "Collecting duct cells: 1.8;Exocrine glandular cells: 5.8;Rod photoreceptor cells: 3.2" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Region enriched" "Detected in single" 15 "cerebral cortex: 4.8" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.7" "Lineage enriched" "Detected in many" 4 "monocytes: 6.7" "Group enriched" "Detected in some" 5 "HMC-1: 13.7;THP-1: 4.5" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" NA NA "CAB026358: , HPA046875: AB_2679851" "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 0.2 0.3 0.0 0.3 0.0 4.8 0.2 0.4 19.9 0.0 0.1 0.1 0.5 36.8 0.2 0.0 0.4 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.4 17.7 0.0 0.0 0.2 0.0 0.2 0.0 0.1 2.0 0.1 0.1 0.0 0.0 0.7 0.0 1.4 1048.8 0.1 0.0 0.0 0.1 3.8 0.0 0.1 0.0 0.3 0.3 1.1 6.7 0.5 1.5 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 1.3 0.4 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.5 4.3 0.2 1.5 6.7 0.9 0.2 0.5 1.4 0.3 0.3 0.2 1.4 1.1 0.5 1.7 0.2 0.1 3.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 PGA4 ENSG00000229183 "Pepsinogen 4, group I (pepsinogen A)" P0DJD7 11 61222216-61231927 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 120 "stomach 1: 924.0" "Cell type enriched" "Detected in single" 128 "Exocrine glandular cells: 100.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "classical monocyte: 7.6;intermediate monocyte: 5.9;non-classical monocyte: 2.1" "Lineage enriched" "Detected in single" 23 "monocytes: 7.6" "Group enriched" "Detected in some" 8 "BJ hTERT+: 17.6;THP-1: 8.9" HPA046875 Supported "Secreted to digestive system" NA NA "HPA046875: AB_2679851" "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 924.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 7.6 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 1.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 100.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGA5 ENSG00000256713 "Pepsinogen 5, group I (pepsinogen A)" P0DJD9 11 61241042-61251448 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "stomach 1: 296.9" "Cell type enriched" "Detected in some" 278 "Exocrine glandular cells: 4020.2" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Group enriched" "Detected in some" 50 "classical monocyte: 3.4;intermediate monocyte: 7.7;non-classical monocyte: 3.7" "Lineage enriched" "Detected in single" 77 "monocytes: 7.7" "Cell line enriched" "Detected in some" 14 "BJ hTERT+: 25.7" HPA046875 Supported "Secreted to digestive system" NA NA "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 296.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4020.2 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.3 1.3 0.9 0.3 0.0 1.0 0.0 14.5 5.9 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA Mitochondria "CAB068215: AB_2665674, HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 12.2 16.5 11.7 14.3 14.0 12.5 18.6 14.6 22.1 8.4 13.9 8.3 9.9 13.6 10.4 9.9 22.0 11.5 13.4 22.6 14.2 12.1 13.9 26.3 8.5 17.6 9.9 11.8 11.9 30.2 8.1 9.6 10.3 10.4 10.1 10.4 8.5 16.0 11.4 27.4 15.2 12.0 10.2 7.5 13.0 11.7 13.6 5.1 17.6 16.3 17.4 14.5 11.6 12.9 4.0 6.7 7.7 3.1 3.3 3.7 1.4 19.2 37.1 7.9 22.3 5.6 4.5 18.6 9.9 6.2 16.7 9.4 46.2 11.2 24.9 18.4 8.6 8.6 16.9 37.2 18.7 6.9 12.2 29.3 29.9 17.4 24.1 12.7 28.3 17.5 5.6 13.8 19.5 21.1 5.5 12.2 20.4 37.4 10.3 6.5 34.9 38.3 28.3 30.1 16.9 26.3 29.4 8.8 19.9 10.8 26.8 29.1 16.4 17.2 24.2 10.7 6.6 30.6 15.7 10.5 8.5 18.6 17.1 24.1 21.6 31.7 35.8 11.1 23.2 14.2 7.7 2.4 0.7 2.5 2.5 3.7 3.6 2.9 2.8 2.0 4.0 2.9 3.6 2.0 3.3 3.1 6.7 2.0 1.4 11.7 14.0 14.6 22.1 14.2 12.1 9.9 11.8 10.4 5.1 3.0 6.7 6.7 10.3 10.2 9.2 12.6 20.4 4.0 0.0 5.2 13.7 5.6 5.0 4.0 12.9 5.3 6.3 0.0 6.7 12.5 3.3 9.0 0.0 21.9 6.4 6.4 12.6 4.3 6.9 15.9 5.5 4.8 3.3 2.8 8.9 3.9 6.9 5.8 6.3 9.0 12.2 6.5 5.5 9.8 9.4 15.2 5.1 4.4 14.0 11.6 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "ductus deferens: 249.6;pancreas: 798.6;stomach 1: 963.7" "Cell type enhanced" "Detected in some" 28 "Alveolar cells type 2: 270.0;Cholangiocytes: 150.3;Pancreatic endocrine cells: 843.0" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "intermediate monocyte: 1.9" "Lineage enriched" "Detected in single" 7 "monocytes: 1.9" "Group enriched" "Detected in some" 11 "Hep G2: 69.6;OE19: 42.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" NA NA Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.1 3.0 249.6 41.7 0.1 0.0 3.3 0.3 16.8 0.1 0.1 0.1 0.1 0.3 139.4 0.0 0.1 0.0 0.1 798.6 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.1 35.9 0.1 0.1 0.1 0.0 0.1 0.1 963.7 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.6 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 1.6 42.3 0.0 0.8 0.0 1.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 23.8 270.0 0.0 3.1 0.3 0.0 0.2 150.3 5.3 9.1 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 117.5 1.0 0.1 95.4 9.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 843.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.4 0.0 0.0 2.6 PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289135-296107 "Enzymes, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 148.7" "Cell type enhanced" "Detected in some" 19 "Alveolar cells type 1: 148.9;Alveolar cells type 2: 104.9;Club cells: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 54.5;U-266/70: 14.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA039383, HPA058829" Uncertain Enhanced Cytosol NA Yes Cytosol "HPA039383: AB_10796225, HPA058829: AB_2683830" "unprognostic (1.40e-3)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.36e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (2.16e-2)" "unprognostic (2.14e-2)" "unprognostic (2.71e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.12e-4)" 5.6 1.8 6.0 16.7 9.3 6.3 10.5 2.9 7.7 12.7 5.6 3.3 10.4 21.1 6.9 14.9 5.6 8.4 8.3 4.4 6.3 1.7 14.8 17.0 15.7 24.6 7.6 2.5 3.5 148.7 2.6 3.6 3.4 8.0 8.5 3.0 7.1 8.9 21.8 5.6 2.4 23.2 5.2 10.1 24.2 4.7 2.3 7.5 6.3 18.0 6.4 15.4 7.3 8.7 2.3 2.5 4.9 4.2 6.9 8.5 2.7 2.1 2.3 4.4 4.8 1.8 1.6 3.3 1.7 1.4 1.0 0.8 2.0 6.1 0.0 2.2 2.0 2.1 1.3 0.3 0.7 0.1 5.2 1.6 1.0 1.5 2.6 2.2 0.1 9.4 5.9 0.6 0.3 0.3 3.7 3.3 54.5 4.0 6.5 0.5 3.1 8.9 4.7 3.4 0.7 0.3 8.5 0.8 3.0 2.3 0.7 0.0 1.0 0.6 3.2 2.9 2.0 2.3 1.1 3.0 2.1 2.9 0.6 0.2 14.3 0.4 2.3 0.3 1.7 2.4 1.5 0.9 1.2 8.5 4.2 7.2 2.1 1.3 4.7 0.6 2.3 3.1 6.1 4.9 6.9 3.2 2.5 0.2 2.7 6.0 9.3 2.9 7.7 6.3 1.7 7.6 2.5 8.0 7.5 148.9 104.9 0.0 0.0 0.0 0.0 0.0 0.0 18.7 58.0 31.4 0.0 0.3 0.0 4.9 0.0 0.0 0.0 0.0 7.1 2.9 0.0 0.0 5.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.8 0.0 0.0 14.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase O95336 19 17511629-17521288 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040744, HPA042032" Approved Supported Nucleoplasm,Cytosol NA NA 10000000 Nucleoplasm Cytosol "HPA040744: AB_2677111, HPA042032: AB_2677809" "unprognostic (3.68e-2)" "unprognostic (8.98e-3)" "unprognostic (1.25e-1)" "unprognostic (9.64e-3)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (2.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.30e-1)" "unprognostic (4.75e-3)" "unprognostic (2.39e-1)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (9.26e-3)" 27.3 31.5 15.6 23.6 13.9 29.3 33.7 9.0 20.1 23.8 29.5 16.0 17.9 21.9 16.6 18.7 38.0 25.9 27.8 18.5 13.9 11.6 25.9 42.7 27.5 60.0 14.3 11.8 32.0 42.1 19.1 16.4 26.5 10.9 23.5 13.5 16.8 31.5 20.7 10.9 27.2 30.8 13.3 16.8 31.4 20.8 15.8 12.2 46.6 26.7 19.2 27.6 18.5 21.6 17.6 46.4 45.8 44.5 17.4 14.9 22.4 18.9 17.1 10.7 7.3 16.5 27.4 20.6 13.0 21.2 13.1 16.9 8.1 28.7 21.0 14.6 20.3 9.3 13.1 6.0 20.3 3.9 10.4 23.5 9.9 7.9 14.5 28.3 10.4 11.0 32.1 28.2 7.8 23.5 13.5 17.6 8.2 11.1 5.1 16.1 20.8 22.9 29.5 14.4 19.7 71.7 15.5 6.9 13.3 17.7 15.3 13.7 16.5 8.3 9.2 18.3 6.1 13.3 19.0 16.4 13.6 3.8 27.1 7.3 9.2 6.4 8.9 19.4 26.9 13.3 15.2 40.8 45.8 14.9 44.5 12.1 16.4 13.2 13.2 46.4 17.6 12.5 12.6 39.6 17.4 41.5 34.4 14.0 22.4 15.6 13.9 9.0 20.1 13.9 11.6 14.3 11.8 10.9 12.2 26.8 37.6 86.9 79.0 57.4 21.4 7.6 91.7 29.4 39.8 45.4 15.7 102.5 94.5 158.8 26.8 57.1 173.6 23.3 181.6 135.6 85.0 78.7 25.3 85.9 223.6 25.4 127.8 76.1 277.9 55.5 84.0 130.9 70.9 196.6 120.1 61.4 172.0 171.9 65.0 148.8 22.8 51.8 55.6 36.4 23.4 84.1 88.0 79.9 140.5 131.2 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 95.8" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 136.1" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.6;monocytes: 7.1;T-cells: 3.7" "Group enriched" "Detected in some" 6 "MCF7: 10.9;T-47d: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 160000000000 "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 3.6 7.1 0.6 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.9 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 10.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.6 0.7 0.3 2.6 2.4 2.5 0.3 1.6 1.3 0.2 0.0 3.6 3.7 2.5 0.6 7.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 136.1 0.3 0.0 0.0 3.1 1.3 2.5 0.3 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 2.9 0.0 0.0 PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211997-2214807 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.7" "Cell type enhanced" "Detected in all" 13 "Cone photoreceptor cells: 380.9;Early spermatids: 399.7;Late spermatids: 977.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" NA NA 46000 "Nuclear bodies" "HPA043096: AB_2678311, HPA046739: AB_2679779" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (2.36e-2)" "unprognostic (7.23e-2)" "unprognostic (2.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.75e-3)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (6.50e-2)" "unprognostic (9.04e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "prognostic favorable (6.42e-4)" 5.7 7.2 10.9 7.3 12.5 9.2 3.6 31.4 21.4 3.9 6.7 4.8 7.3 7.9 4.7 6.5 3.6 3.7 4.4 15.6 11.4 9.8 6.1 5.5 6.2 7.5 9.6 12.8 2.5 6.6 8.7 6.1 6.9 17.8 5.3 5.3 4.7 6.2 6.8 40.7 5.6 7.5 4.9 6.0 8.0 6.7 23.0 7.4 5.9 8.8 7.9 5.0 4.2 2.6 1.8 1.9 6.1 3.4 0.3 2.2 0.4 9.2 15.2 10.8 10.3 4.5 3.5 20.8 10.9 5.2 10.1 10.4 23.6 11.8 7.1 10.8 5.0 8.2 15.6 7.6 9.3 4.5 9.6 21.1 7.0 23.1 10.6 3.0 12.5 11.7 4.2 4.2 9.4 3.5 3.6 6.5 11.7 12.8 7.5 5.5 25.3 14.1 20.5 14.3 5.7 14.4 23.1 9.4 15.9 8.3 5.9 14.5 8.8 9.7 18.3 7.5 8.1 13.6 14.6 6.4 10.4 13.7 9.3 10.8 17.8 7.7 10.0 3.5 11.1 8.0 0.0 2.3 6.1 2.2 3.4 0.3 0.7 1.3 1.6 1.6 1.8 0.8 1.4 1.4 0.3 3.1 1.9 1.3 0.4 10.9 12.5 31.4 21.4 11.4 9.8 9.6 12.8 17.8 7.4 6.0 8.5 13.4 7.0 20.7 194.2 37.5 12.7 1.4 5.7 38.4 380.9 102.8 49.7 8.0 399.7 21.1 46.4 23.3 12.2 86.7 22.8 21.1 10.3 30.7 50.8 136.7 28.6 19.0 30.8 977.0 23.9 41.2 33.7 8.2 22.2 54.1 10.8 24.6 26.5 28.7 225.9 38.8 21.2 167.9 61.0 27.9 45.5 23.5 34.6 14.4 PGPEP1 "Pcp, PGP, PGP-I, PGPI" ENSG00000130517 "Pyroglutamyl-peptidase I" Q9NXJ5 19 18340587-18369950 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Proximal tubular cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035368, HPA055277" Approved Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA035368: AB_10601388, HPA055277: AB_2682770" "unprognostic (9.52e-3)" "unprognostic (1.37e-2)" "unprognostic (6.95e-2)" "unprognostic (5.74e-3)" "unprognostic (5.29e-2)" "unprognostic (6.60e-2)" "unprognostic (1.96e-2)" "unprognostic (2.11e-3)" "prognostic favorable (6.80e-4)" "unprognostic (2.79e-2)" "prognostic favorable (1.71e-4)" "unprognostic (4.81e-3)" "prognostic favorable (3.71e-8)" "unprognostic (1.12e-2)" "unprognostic (1.66e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-3)" 11.0 18.6 14.8 10.1 14.9 12.4 10.7 8.1 12.5 13.9 23.3 14.8 25.3 23.6 8.2 16.0 6.3 10.0 16.7 20.6 18.2 15.4 29.9 29.7 9.4 11.4 17.8 7.3 13.2 26.6 15.1 17.1 7.5 12.5 13.4 17.2 13.7 22.8 23.6 25.2 3.6 33.6 12.1 25.5 16.2 15.4 4.2 15.6 8.6 11.5 7.4 7.0 12.8 10.0 3.9 3.3 17.6 6.1 4.3 4.9 3.6 4.7 7.5 6.3 6.3 8.0 6.3 7.7 5.7 8.9 3.9 5.9 5.3 10.2 7.3 9.6 9.3 7.0 1.3 2.4 1.3 2.2 8.6 2.7 8.0 7.5 14.9 11.3 4.7 33.4 6.3 2.8 3.0 0.5 14.2 5.8 12.7 14.6 11.1 3.2 7.6 4.7 3.8 6.4 3.2 2.3 0.0 2.3 6.5 4.2 7.5 2.2 3.5 1.1 0.6 10.1 4.3 2.9 9.5 8.9 4.5 3.1 5.9 2.4 13.8 6.5 4.4 12.1 13.2 4.1 17.6 5.4 7.1 4.9 5.4 2.8 2.0 3.4 4.4 3.3 3.9 4.3 4.0 3.1 4.3 6.1 2.2 3.8 3.6 14.8 14.9 8.1 12.5 18.2 15.4 17.8 7.3 12.5 15.6 8.9 16.7 9.0 10.8 2.1 3.9 17.8 30.6 1.4 6.8 29.6 9.8 15.9 6.6 18.9 0.5 8.0 61.2 0.0 38.9 18.4 7.3 12.7 33.6 67.2 20.3 4.8 37.4 13.5 24.6 0.7 7.2 19.7 15.1 2.8 20.9 6.6 35.6 28.8 19.1 73.1 6.0 6.5 8.0 2.1 4.1 1.0 15.7 15.8 28.1 13.3 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715450-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.0" "Cell type enhanced" "Detected in many" 8 "Muller glia cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 7.7;T-reg: 2.4" "Group enriched" "Detected in many" 7 "granulocytes: 7.7;T-cells: 2.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Uncertain "Intracellular and membrane" NA NA "HPA020200: AB_2670383" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favorable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.8 10.6 22.1 2.3 34.1 7.4 7.4 8.3 29.6 4.3 6.0 48.0 0.9 6.2 4.4 2.5 6.1 4.0 4.9 3.0 22.4 12.3 4.0 18.5 3.4 3.0 44.4 13.8 5.5 8.0 9.6 5.6 6.3 20.6 5.0 6.7 4.4 11.2 4.5 3.9 9.1 5.5 4.0 18.6 2.0 5.6 11.5 44.8 2.3 5.6 1.6 4.1 5.6 3.2 0.6 0.7 7.7 0.2 0.6 2.4 0.1 9.0 3.4 14.0 4.6 2.4 2.0 10.9 2.7 2.5 5.4 5.6 7.4 5.5 6.1 1.7 4.1 2.1 11.1 7.2 4.3 7.0 18.8 6.0 2.0 3.7 13.7 3.4 3.1 1.0 2.1 2.9 5.8 5.3 4.4 3.8 3.3 5.2 12.3 5.2 2.0 2.3 2.7 5.6 1.8 3.3 21.7 7.9 7.3 3.1 11.8 6.5 2.6 3.0 6.8 5.6 8.5 3.0 8.9 4.8 4.5 2.1 2.6 6.3 1.4 0.7 7.2 2.6 3.6 3.4 0.0 0.2 0.1 0.7 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.4 0.1 7.7 0.6 0.2 0.3 2.4 0.1 22.1 34.1 8.3 21.1 22.4 12.3 44.4 13.8 20.6 44.8 3.0 1.0 0.0 3.7 14.9 14.8 3.3 15.3 8.1 5.7 0.0 27.5 10.8 1.7 2.5 26.9 5.8 5.6 0.0 3.6 4.7 6.0 6.4 2.3 16.3 2.1 25.4 11.6 6.2 2.8 24.6 5.5 4.6 23.6 3.6 7.9 82.5 3.7 5.8 3.5 1.8 16.7 0.0 4.4 5.0 16.9 16.3 21.9 0.0 11.5 7.4 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 29.9" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 98.2;Enterocytes: 51.9;Rod photoreceptor cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" NA No Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 6.4 4.7 12.5 7.0 10.9 8.1 8.4 17.4 14.9 4.4 16.6 4.6 4.3 15.8 5.8 4.9 2.7 4.7 4.1 4.6 11.7 9.0 5.4 4.9 4.8 5.0 6.2 14.9 7.2 4.9 10.2 7.3 4.3 12.6 4.7 17.8 13.2 2.9 5.7 5.3 3.0 29.9 7.0 7.6 3.9 4.2 10.8 4.7 1.0 9.9 1.1 4.9 4.7 9.8 2.4 2.2 1.2 0.7 3.5 1.5 0.4 4.9 6.5 7.1 7.9 5.7 6.9 4.1 7.4 6.7 10.7 8.8 5.9 1.6 9.8 2.9 12.2 7.7 10.5 10.2 3.8 13.9 3.4 5.5 2.7 5.6 3.9 4.5 2.3 4.3 5.1 2.2 15.2 5.0 4.5 4.0 3.4 2.4 2.7 7.4 10.4 3.2 1.8 5.5 1.5 1.7 5.1 6.2 3.2 5.1 3.8 6.2 3.3 15.9 4.4 2.6 5.7 5.4 1.4 5.5 10.8 7.8 4.5 6.1 6.1 4.3 10.1 6.7 1.9 2.4 0.8 0.5 0.2 1.0 0.7 0.9 2.4 0.8 1.5 0.6 1.6 1.1 0.9 1.2 3.5 0.7 2.2 1.3 0.4 12.5 10.9 17.4 14.9 11.7 9.0 6.2 14.9 12.6 4.7 8.9 2.1 5.2 4.7 8.2 18.7 2.3 0.0 2.7 4.5 3.5 98.2 3.8 0.0 2.4 9.7 3.7 51.9 0.0 2.0 0.3 7.2 5.0 10.3 3.9 1.3 22.3 5.8 3.1 5.4 3.6 4.9 2.2 13.5 2.8 6.7 6.3 2.8 31.6 4.9 4.3 60.3 6.5 5.6 29.1 18.3 8.0 1.1 3.5 7.2 2.1 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase" Q8TCT1 17 49223362-49230766 "Enzymes, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 80.0;testis: 52.3" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1098.7" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "cerebral cortex: 10.2;pons and medulla: 8.2" "Group enriched" "Detected in some" 171 "eosinophil: 30.6;neutrophil: 80.0" "Lineage enriched" "Detected in single" 248 "granulocytes: 80.0" "Cell line enhanced" "Detected in some" "Daudi: 8.6;EFO-21: 5.8;HDLM-2: 6.1;SuSa: 8.9" "Low region specificity" "Detected in all" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Actin filaments" "Plasma membrane" "HPA065025: AB_2732727" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.1 2.9 1.9 15.3 0.7 1.0 10.2 0.6 0.6 0.2 0.2 2.5 0.9 2.7 0.9 1.3 2.1 1.0 1.7 1.3 1.0 0.9 2.5 2.0 2.1 1.5 1.1 1.0 0.1 0.8 7.6 8.2 0.9 0.0 1.6 0.9 0.5 2.2 1.1 2.6 0.3 1.5 12.6 0.7 52.3 0.1 0.0 0.8 0.1 0.1 1.4 1.3 0.0 0.0 80.0 0.3 0.0 0.0 0.1 0.0 1.1 0.0 2.0 0.1 0.2 0.0 0.3 0.4 0.0 0.1 2.7 0.0 8.6 5.8 0.0 3.3 0.0 1.6 0.5 0.1 6.1 0.2 1.2 1.1 0.4 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.6 0.1 0.0 0.4 0.0 0.3 1.6 1.7 3.2 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 8.9 0.2 0.1 3.5 0.4 2.8 1.9 0.0 0.2 0.3 0.6 2.5 3.3 0.3 0.0 0.1 30.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.0 0.0 0.3 0.0 0.0 0.1 1.1 1.9 1.0 10.2 1.7 1.3 2.1 1.5 8.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 185.3 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.6 0.0 1098.7 7.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.6 0.0 0.4 0.0 0.0 8.2 3.8 0.0 198.7 0.0 0.0 0.0 PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 12 "Early spermatids: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA034726: AB_10602191, HPA034727: AB_2674302" "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (3.82e-6)" "unprognostic (4.31e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "prognostic favorable (9.53e-4)" "unprognostic (4.10e-1)" "unprognostic (2.60e-1)" "unprognostic (6.12e-2)" "unprognostic (7.53e-2)" 8.7 4.0 9.0 5.7 9.7 3.3 14.2 14.2 7.8 8.4 8.2 5.8 6.3 8.2 8.6 5.9 4.6 8.1 6.2 5.7 6.7 5.5 7.5 5.0 4.3 3.6 6.0 9.1 8.2 8.9 10.9 21.3 3.9 7.8 17.4 7.8 6.4 10.5 7.8 6.4 5.2 7.9 6.2 9.7 3.4 6.3 25.4 8.0 5.5 13.0 3.9 3.9 9.1 5.7 8.8 4.6 1.5 1.0 10.5 5.7 1.8 5.7 1.6 4.1 5.6 7.9 2.5 16.3 2.5 1.7 3.9 4.4 5.6 4.4 5.6 5.6 1.9 8.1 4.5 5.5 3.0 3.2 8.3 6.4 5.6 4.9 9.6 5.2 4.5 5.1 4.6 5.8 4.5 6.0 3.3 3.5 8.0 9.2 5.8 2.4 5.3 3.1 5.9 5.6 3.7 2.1 3.2 2.5 4.3 6.2 17.3 17.5 6.0 5.4 2.8 6.0 5.2 7.5 2.8 2.0 4.3 4.1 4.0 2.7 5.6 5.2 5.0 5.1 2.8 4.5 0.0 0.9 1.1 3.9 1.0 5.5 6.8 4.3 3.7 1.0 8.8 5.7 5.6 1.5 10.5 0.9 4.6 4.4 1.8 9.0 9.7 14.2 7.8 6.7 5.5 6.0 9.1 7.8 8.0 3.0 2.2 2.7 9.2 2.3 8.7 2.8 2.5 13.4 1.2 3.5 5.9 8.6 8.3 5.9 91.4 4.5 5.9 0.0 9.9 8.8 3.0 7.0 0.0 2.8 2.5 6.4 14.5 2.5 0.0 23.3 4.4 1.9 3.3 1.0 8.2 5.2 6.7 8.4 4.6 9.8 10.2 0.0 5.1 27.9 11.7 3.8 4.6 4.3 8.1 4.3 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 430000 Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 15.8 26.4 31.5 12.1 28.0 11.7 15.3 14.7 27.2 19.2 15.7 18.5 13.7 14.7 11.2 21.7 13.7 21.1 14.2 59.1 22.7 19.3 18.4 12.6 12.1 12.7 27.0 21.0 13.7 46.5 15.6 21.2 14.7 20.8 20.2 11.6 14.1 30.5 22.6 86.0 9.2 16.3 16.9 24.3 10.3 13.4 13.8 18.6 7.5 20.7 19.8 10.4 12.0 9.8 24.9 48.8 3.3 35.4 20.0 24.3 32.1 7.1 52.0 29.7 18.9 19.2 34.9 43.7 16.6 21.2 20.3 18.1 18.9 16.3 15.2 20.2 20.5 24.3 18.9 6.4 37.5 6.4 13.6 13.2 4.8 34.2 41.5 23.9 9.5 19.5 43.5 30.9 11.6 14.0 18.4 26.6 11.9 11.5 14.1 31.4 40.6 13.8 20.0 23.5 47.6 22.4 11.5 13.0 25.1 32.1 11.9 14.6 13.8 17.9 21.0 8.6 14.8 15.9 26.4 21.6 42.5 13.2 11.7 15.3 9.4 9.1 9.3 24.0 6.9 25.4 2.9 35.4 3.3 24.3 34.2 20.9 24.9 21.1 21.9 37.5 16.5 15.0 21.3 1.7 20.0 24.0 48.8 22.9 32.1 31.5 28.0 14.7 27.2 22.7 19.3 27.0 21.0 20.8 18.6 89.3 132.7 80.4 156.2 133.5 37.9 336.8 191.1 136.5 125.1 205.9 21.6 300.5 633.3 164.3 214.6 110.1 411.5 70.0 220.3 372.9 227.8 244.3 120.2 179.9 249.5 63.5 254.7 94.5 103.8 640.4 189.8 148.3 317.2 367.9 241.4 126.9 202.0 354.2 210.0 509.4 53.8 84.1 248.0 93.6 149.9 141.4 220.8 93.5 262.8 160.3 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.3" "Group enriched" "Detected in many" 5 "Early spermatids: 22.3;Erythroid cells: 70.0" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Lineage enriched" "Detected in single" 5 "T-cells: 3.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 1.8 1.1 0.6 12.9 0.6 6.0 0.6 0.6 1.2 1.2 5.2 0.6 0.6 3.3 2.0 1.3 4.6 0.8 1.4 0.9 0.6 1.8 0.7 0.6 1.9 7.5 0.9 0.6 0.6 0.6 0.0 0.6 1.4 1.0 2.5 1.8 0.9 0.8 1.2 0.6 1.6 3.7 2.1 0.6 7.0 2.7 3.3 0.6 14.3 0.6 5.1 6.0 1.8 1.9 0.7 0.3 0.0 0.0 0.0 3.2 0.4 5.2 6.1 15.0 6.0 2.7 3.2 5.5 5.1 2.8 5.2 4.0 9.6 8.8 6.3 2.1 2.5 4.8 14.5 15.3 4.3 1.9 10.0 5.6 7.3 17.1 6.9 1.4 2.9 6.0 1.8 0.0 2.3 1.9 1.3 5.3 9.5 4.8 12.7 4.9 4.6 3.1 12.2 12.2 6.6 4.2 6.5 5.0 8.9 2.9 2.9 6.2 4.0 3.9 4.4 2.3 6.9 4.9 3.2 3.6 3.1 16.4 5.0 9.4 10.2 9.4 6.0 3.0 12.9 4.4 0.0 0.0 0.0 1.5 0.0 0.5 0.7 0.1 1.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.3 3.2 0.4 0.6 0.6 0.6 1.2 0.6 1.8 0.9 0.6 1.0 0.6 0.0 1.4 0.8 0.6 1.6 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 22.3 1.5 0.3 70.0 0.0 5.6 2.6 0.9 0.0 0.0 4.8 0.0 0.0 7.4 2.2 1.3 1.4 3.1 0.0 0.0 0.8 0.6 0.2 0.0 2.1 0.0 0.8 6.5 2.7 0.1 1.9 0.9 0.9 8.9 0.9 1.1 PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis" Hydrolase "Deafness, Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" No No "Nucleoplasm, Cytosol" "HPA012739: AB_1855367" "unprognostic (3.07e-2)" "unprognostic (2.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (9.39e-5)" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.57e-4)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.19e-2)" "unprognostic (2.13e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-3)" 17.3 12.6 11.1 14.3 18.8 8.6 18.0 14.6 15.6 12.9 13.0 17.6 12.8 17.1 19.8 20.2 12.6 13.1 12.7 8.8 8.5 7.5 11.2 18.5 12.5 12.0 14.5 10.7 16.5 16.5 11.9 18.1 10.3 13.6 14.0 14.4 15.5 14.8 16.3 13.4 20.0 15.8 10.1 9.7 12.3 14.8 11.1 13.6 13.7 15.7 11.1 20.4 10.9 12.3 5.2 7.4 5.5 3.7 5.4 9.3 3.3 7.9 11.4 7.7 6.3 11.0 10.4 3.2 4.4 5.3 7.5 13.3 11.6 10.2 3.9 9.1 4.3 4.5 11.6 9.5 5.6 10.7 8.3 24.8 7.7 7.9 13.8 11.8 3.3 5.0 8.8 14.7 13.0 14.8 7.6 8.5 13.1 9.1 5.0 5.9 7.9 6.0 7.7 3.0 15.9 5.9 5.9 6.5 11.2 8.4 4.3 4.1 5.8 4.6 3.3 9.0 20.8 3.5 3.0 5.5 6.8 4.2 4.4 12.5 3.5 0.1 6.3 8.4 8.2 4.2 0.0 3.7 5.5 6.5 3.2 5.6 5.2 8.5 5.0 2.7 4.4 9.3 7.5 0.0 5.4 2.4 7.4 6.7 3.3 11.1 18.8 14.6 15.6 8.5 7.5 14.5 10.7 13.6 13.6 8.9 16.0 3.7 8.0 3.9 11.3 1.7 7.6 10.7 12.5 12.2 9.8 13.3 5.0 5.6 2.1 5.8 6.8 0.0 6.4 6.1 6.0 6.8 4.7 9.4 4.5 6.4 7.5 3.1 2.7 1.9 7.2 5.1 3.3 1.8 10.0 6.7 7.4 7.0 10.6 4.4 12.3 0.0 6.6 13.7 8.3 5.3 8.0 8.7 10.8 8.8 PIP4P1 "C14orf9, MGC26684, TMEM55B" ENSG00000165782 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1" Q86T03 14 20457719-20461612 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 14 "Cytotrophoblasts: 66.6;Hofbauer cells: 47.2;Syncytiotrophoblasts: 139.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048528 Approved NA NA "HPA048528: AB_2680427" "unprognostic (1.84e-1)" "unprognostic (6.23e-2)" "unprognostic (1.81e-1)" "unprognostic (7.07e-2)" "unprognostic (2.04e-1)" "unprognostic (8.51e-2)" "unprognostic (1.71e-2)" "unprognostic (3.37e-3)" "unprognostic (4.94e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.85e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.80e-2)" "unprognostic (1.47e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" 15.9 16.8 19.7 15.1 24.7 42.2 15.6 23.8 41.0 14.4 19.2 22.9 12.6 17.9 15.6 29.3 16.5 16.4 18.0 15.9 20.2 23.5 18.7 17.7 17.3 16.8 18.9 22.2 15.3 21.1 28.4 20.0 22.6 28.5 16.1 16.5 20.3 16.1 17.2 22.2 22.1 22.1 16.7 17.0 22.0 18.0 13.3 18.5 14.2 17.7 12.8 20.8 17.5 14.0 13.3 10.6 6.9 3.3 4.6 6.6 2.4 10.3 16.3 11.0 12.8 17.3 10.7 20.3 9.8 19.4 13.5 16.5 9.6 16.9 9.3 8.5 12.4 39.5 10.9 13.4 10.9 12.0 12.3 9.9 6.7 7.8 14.1 23.6 12.3 13.8 13.9 14.9 15.6 16.0 12.4 12.5 14.5 5.6 19.1 11.2 11.8 16.7 10.9 7.3 16.4 22.5 12.4 10.6 6.1 12.7 23.4 15.9 11.8 10.1 16.7 12.6 9.9 8.4 11.7 8.6 12.4 15.8 18.6 8.8 21.5 27.5 13.3 8.6 9.5 13.5 1.3 3.3 6.9 4.7 2.4 4.0 13.3 5.6 5.1 4.1 11.3 6.4 6.6 4.2 4.6 2.0 10.6 4.2 2.4 19.7 24.7 23.8 41.0 20.2 23.5 18.9 22.2 28.5 18.5 8.9 8.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 5.7 21.0 0.0 66.6 16.6 31.2 0.0 0.0 0.0 0.0 35.5 31.3 0.0 0.0 3.5 0.0 47.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 22.6 0.0 0.0 27.8 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 139.8 0.0 0.0 0.0 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993796-91041064 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 27.7;Distal tubular cells: 41.4;Extravillous trophoblasts: 27.3;Hofbauer cells: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 36.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA 57000 "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 15.8 18.6 18.7 9.1 19.5 35.2 11.7 21.4 31.7 14.2 16.5 11.1 7.3 4.4 15.0 7.1 8.5 8.6 15.5 26.0 18.2 23.5 13.7 5.7 8.1 11.8 22.8 20.0 16.1 4.8 14.6 13.4 12.2 25.5 12.3 7.2 17.4 10.1 18.6 16.7 8.0 6.6 18.6 25.4 11.2 9.6 9.7 21.1 7.1 9.4 6.9 7.7 13.3 10.5 1.5 5.3 36.2 5.6 1.2 2.4 2.9 2.6 1.6 9.4 5.9 15.3 18.1 1.9 11.4 13.5 5.8 8.6 1.0 4.4 5.1 1.5 10.9 5.8 0.6 2.2 3.7 7.6 4.7 4.6 8.1 1.7 0.8 13.8 1.9 7.3 10.0 2.4 7.3 5.4 15.5 5.5 1.5 4.0 17.0 20.1 1.8 5.4 4.8 4.9 0.0 5.9 2.2 3.8 6.1 8.1 1.6 1.0 5.3 0.7 3.6 13.9 6.6 0.1 3.3 8.3 10.4 4.3 6.0 4.8 6.8 4.1 3.1 18.0 3.4 13.9 0.3 5.6 5.3 0.8 2.6 1.3 1.5 1.8 0.9 5.3 1.1 2.4 1.0 36.2 1.2 1.0 3.1 1.5 2.9 18.7 19.5 21.4 31.7 18.2 23.5 22.8 20.0 25.5 21.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 5.7 8.7 0.0 27.7 41.4 15.5 0.0 0.0 0.0 0.0 7.7 27.3 0.0 0.0 8.1 0.0 39.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 6.4 0.0 0.0 11.2 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672545-14694669 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.4;stomach 1: 13.0" "Cell type enhanced" "Detected in many" 10 "Enterocytes: 54.8;Exocrine glandular cells: 106.2;Extravillous trophoblasts: 45.9;Mucus-secreting cells: 110.3;Paneth cells: 80.4" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 2.6;CAPAN-2: 4.2;OE19: 4.6;SK-BR-3: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041893 Uncertain "Secreted in other tissues" NA NA "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favorable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.3 9.4 2.4 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 13.0 2.1 0.0 0.0 2.8 0.0 0.9 0.5 2.0 0.5 0.1 0.4 0.1 0.1 0.9 0.1 0.1 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.6 4.2 0.3 0.4 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.7 0.0 1.9 0.3 0.2 0.4 4.6 0.1 0.8 0.3 0.2 0.0 0.3 0.6 0.5 1.0 2.6 0.3 0.3 0.4 0.4 0.8 0.0 0.3 0.1 0.0 0.7 2.1 0.7 0.6 0.1 0.1 0.1 0.5 0.5 0.3 0.4 0.3 0.1 0.2 0.4 0.5 0.9 0.3 0.3 2.0 0.1 0.3 0.3 0.1 0.1 32.8 17.2 0.0 0.7 0.0 0.0 0.0 10.2 32.1 9.1 1.8 0.0 0.4 0.0 0.3 0.3 0.0 54.8 0.0 106.2 45.9 0.0 1.9 0.0 0.0 0.8 0.0 12.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 110.3 0.0 15.5 80.4 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.5 0.0 23.8 12.6 PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730077 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" NA NA "HPA035908: AB_2674856, HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" 9.8 9.9 13.1 4.4 16.2 5.6 12.9 14.5 14.3 9.6 12.2 13.4 7.3 11.9 8.9 8.2 12.6 9.2 9.2 21.0 13.0 11.4 15.3 20.6 7.8 4.9 16.8 11.7 11.9 38.8 22.8 19.0 10.4 12.7 16.4 12.0 10.7 12.1 8.3 21.1 9.8 16.3 8.1 20.3 5.5 10.0 5.7 12.4 4.9 19.0 9.2 6.2 7.5 7.7 4.9 8.7 3.6 4.6 4.9 10.2 13.8 9.6 3.6 2.8 4.2 9.0 9.0 5.5 8.9 7.1 5.0 5.3 8.9 17.0 13.8 6.7 6.5 8.4 5.4 8.6 11.5 7.7 5.1 13.4 4.9 10.4 5.3 8.9 10.6 3.5 9.1 13.4 5.1 12.6 9.1 5.0 13.0 27.0 6.4 8.5 17.0 8.6 4.8 5.0 22.0 14.0 5.2 8.5 10.9 9.4 14.3 18.1 6.0 7.8 20.7 6.7 7.6 12.4 2.3 5.9 7.3 6.1 7.5 6.1 10.9 19.6 10.2 8.2 6.2 9.1 3.6 4.6 2.7 7.2 2.9 6.6 4.2 9.0 6.9 8.7 4.9 10.2 9.2 2.2 4.9 4.4 7.6 8.7 13.8 13.1 16.2 14.5 14.3 13.0 11.4 16.8 11.7 12.7 12.4 23.8 17.9 15.2 28.9 32.5 46.8 53.4 30.6 10.7 13.6 21.0 47.1 33.9 23.2 12.4 18.0 12.7 27.4 23.3 22.2 44.9 23.9 62.2 13.9 86.9 17.1 25.4 103.4 18.4 19.4 7.1 30.8 8.9 28.7 1.8 52.7 39.7 13.5 35.1 32.5 14.6 39.5 19.4 19.1 55.2 41.1 37.3 28.8 13.8 59.3 35.7 PLA2G16 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754." ENSG00000176485 "Phospholipase A2 group XVI" P53816 11 63573195-63616883 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.6" "Cell type enhanced" "Detected in many" 9 "monocytes: 759.2;Proximal tubular cells: 471.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 52.4" "Group enriched" "Detected in many" 5 "dendritic cells: 52.4;T-cells: 16.0" "Cell line enhanced" "Detected in many" "A549: 32.7;ASC diff: 37.1;CAPAN-2: 59.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Uncertain Supported Mitochondria NA NA Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 113.6 15.2 32.0 4.4 39.4 1.6 33.9 4.8 30.2 6.1 7.2 46.6 6.1 4.0 5.0 11.5 5.9 13.9 12.9 39.0 37.6 25.2 24.7 28.9 13.5 4.5 58.4 22.2 30.9 13.2 15.1 8.1 16.2 30.5 5.9 3.7 8.8 10.1 13.2 37.8 2.4 7.5 8.0 70.4 6.4 10.2 17.8 48.9 0.1 17.1 11.1 2.3 8.0 4.7 2.1 52.4 0.4 6.2 5.3 16.0 6.4 20.6 32.7 0.9 0.0 37.1 6.4 6.0 0.7 6.6 5.5 2.7 7.4 59.7 0.0 13.8 1.6 18.0 1.0 30.9 1.6 4.2 25.5 1.2 0.3 7.8 1.2 22.1 0.0 0.3 3.8 0.1 13.6 0.5 22.0 8.6 0.0 0.3 2.3 5.8 3.6 0.0 0.1 2.6 13.0 10.6 0.0 0.0 2.0 17.3 2.9 0.4 2.4 4.4 12.5 6.8 14.0 27.1 1.0 12.6 2.4 0.1 8.3 1.8 9.8 6.4 0.0 9.9 0.0 0.2 0.0 6.2 0.0 16.0 2.4 8.8 2.1 3.7 11.6 1.7 0.3 1.2 9.4 0.4 5.3 0.1 52.4 2.4 6.4 32.0 39.4 4.8 21.9 37.6 25.2 58.4 22.2 30.5 48.9 95.3 77.4 17.6 17.3 10.3 10.6 128.7 96.8 113.8 45.5 109.9 3.9 112.1 96.2 54.1 56.9 116.5 22.2 0.0 99.5 300.4 35.3 29.0 56.6 210.7 56.9 38.1 3.4 165.7 48.0 16.0 28.7 51.4 25.3 759.2 4.5 120.3 123.3 14.4 20.5 471.4 17.2 12.9 42.8 135.2 4.9 8.2 243.0 69.8 1.7 59.6 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322111-120327789 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 933 "pancreas: 2360.6" "Cell type enriched" "Detected in many" 10 "Exocrine glandular cells: 17927.2" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.5" "Group enriched" "Detected in many" 19 "NK-cells: 1.3;T-cells: 2.5" "Cell line enhanced" "Detected in some" "EFO-21: 2.2;Hep G2: 6.4;U-2 OS: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" NA NA 3900000 "HPA047822: AB_2680169, HPA060803: AB_2684369" "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 1.1 0.1 0.1 0.1 1.1 2360.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.3 2.5 0.9 0.2 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.5 0.0 0.3 1.3 0.3 1.6 0.0 0.0 0.3 0.0 0.1 0.6 0.0 1.0 0.2 4.7 0.6 0.6 0.0 1.2 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.3 0.0 0.0 2.5 0.9 0.0 1.3 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 11.9 65.5 0.0 0.1 0.0 0.0 0.3 0.0 1.4 1.2 0.0 0.0 0.0 1.7 16.1 7.5 0.0 0.7 0.0 17927.2 0.0 0.0 0.2 0.0 1.6 0.0 0.0 1.2 0.0 0.0 27.8 2.8 0.3 0.0 76.7 1.0 0.0 1839.8 1.1 3.2 2.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.7 1.2 0.0 PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Antimicrobial, Bacteriolytic enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 377.9" "Cell type enhanced" "Detected in many" 11 "Enterocytes: 366.3;Exocrine glandular cells: 945.9;Glandular cells: 937.5;Paneth cells: 354.3;Undifferentiated cells: 591.0" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Hep G2: 23.4;OE19: 64.1;RT4: 21.5" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" NA NA 1000000 290000 "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" 25.2 1.0 0.0 13.1 0.0 0.6 14.0 0.0 0.6 1.4 63.9 0.0 0.1 35.0 0.7 22.7 31.5 11.7 2.4 105.4 0.0 0.0 1.6 377.9 3.0 6.5 0.0 0.0 35.6 2.4 0.6 0.5 15.5 0.0 27.1 68.2 6.1 9.5 1.0 30.6 5.0 99.0 39.7 0.0 0.6 4.0 9.8 0.0 0.0 16.0 8.9 19.3 39.0 72.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.6 0.0 21.5 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 4.1 6.7 10.0 12.4 0.0 7.2 5.1 2.7 6.8 0.0 0.0 2.8 1.7 0.0 3.0 8.4 366.3 0.0 945.9 3.3 308.9 937.5 4.6 51.6 8.2 0.0 59.8 35.0 6.0 7.5 158.5 4.9 13.5 0.0 270.5 0.0 3.6 354.3 1.1 0.0 0.0 0.0 11.3 0.5 0.1 14.6 5.7 8.4 591.0 9.1 PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 39.9" "Group enriched" "Detected in some" 10 "Kupffer cells: 2.2;Melanocytes: 5.0" "Cancer enriched" "Detected in many" 6 "testis cancer: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.6;naive B-cell: 5.6;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 5 "B-cells: 6.6;dendritic cells: 3.4" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 13.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted - unknown location" NA NA "prognostic favorable (4.35e-4)" "prognostic favorable (8.15e-5)" "unprognostic (3.88e-3)" "prognostic favorable (9.74e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (1.82e-5)" "unprognostic (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (2.60e-1)" 0.4 0.3 0.3 38.8 0.3 0.0 0.4 0.3 0.3 0.3 0.9 0.0 0.0 0.3 0.3 0.2 0.4 0.5 0.4 0.3 0.3 0.3 0.4 0.4 1.0 39.9 0.3 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.4 1.2 0.1 5.0 0.3 0.3 0.3 7.7 0.0 0.3 18.1 0.6 0.3 0.0 6.6 0.7 0.5 33.0 2.5 0.3 6.6 3.4 1.0 0.2 0.3 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 13.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.3 0.2 2.1 0.1 0.2 0.1 0.1 0.0 1.0 0.2 0.2 0.1 0.1 0.1 6.6 0.1 0.1 0.1 5.6 0.1 0.1 0.4 0.3 0.1 3.4 0.0 0.2 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "lymphoid tissue: 7.7;skin 1: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.9;CAPAN-2: 1.2;OE19: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" NA NA "HPA064085: AB_2685188" "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G2F ENSG00000158786 "Phospholipase A2 group IIF" Q9BZM2 1 20139326-20150386 "Enzymes, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Innate immunity, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.1;skin 1: 13.7;urinary bladder: 19.5" "Cell type enhanced" "Detected in some" 13 "Cardiomyocytes: 1.0;Collecting duct cells: 1.8;Suprabasal keratinocytes: 1.5" "Cancer enriched" "Detected in some" 18 "urothelial cancer: 17.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 67 "RT4: 56.2" "Region enriched" "Detected in single" 4 "hippocampal formation: 3.3" "Not detected" "Not detected" "Intracellular and membrane" NA NA "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.79e-2)" "unprognostic (5.11e-2)" "unprognostic (4.63e-2)" "unprognostic (4.83e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-2)" "unprognostic (3.36e-5)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-1)" "prognostic favorable (3.86e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.8 0.0 7.7 0.0 0.0 0.0 0.0 0.0 13.7 0.1 6.5 0.0 0.0 0.3 0.1 0.0 2.8 0.0 6.3 11.1 19.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.7 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134809-31140607 "Enzymes, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 13.1;skin 1: 14.1;tongue: 17.4" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 15.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 14.2;AN3-CA: 14.3;NTERA-2: 7.3;SCLC-21H: 11.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021016 Uncertain "Secreted to blood" NA NA "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.1 0.0 0.1 0.1 0.2 0.0 2.0 0.4 0.9 5.3 0.1 0.1 1.9 0.5 0.3 0.1 13.1 0.0 0.1 0.1 0.6 0.0 0.3 0.1 4.2 0.1 0.1 0.4 0.1 0.1 1.7 0.1 0.1 3.1 0.4 0.0 0.8 1.8 0.5 0.3 14.1 0.1 0.1 0.1 0.1 0.9 0.3 0.1 0.4 0.8 17.4 3.5 0.1 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 14.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.9 0.6 0.0 0.1 0.4 3.1 0.1 0.0 2.2 0.0 0.1 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 15.6 0.0 0.0 0.0 0.4 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828953-186988981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 52.6;parathyroid gland: 63.5;seminal vesicle: 56.1" "Cell type enhanced" "Detected in many" 7 "Basal keratinocytes: 19.1;Peritubular cells: 13.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 7.1;eosinophil: 7.7;intermediate monocyte: 8.4;myeloid DC: 7.8;non-classical monocyte: 3.9;plasmacytoid DC: 3.2" "Group enriched" "Detected in many" 7 "dendritic cells: 7.8;granulocytes: 7.7;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 23.0;OE19: 33.2;RPMI-8226: 28.5;U-2197: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 78000 Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 6.0 8.6 3.4 3.5 5.3 2.2 3.8 1.5 4.7 8.5 10.9 2.9 52.6 5.4 7.7 7.4 7.0 12.3 4.2 6.6 3.3 2.5 6.7 1.1 4.9 5.2 6.5 1.4 5.1 3.8 63.5 2.7 2.9 5.6 10.9 4.2 2.9 5.8 56.1 0.6 6.1 10.3 14.6 7.5 4.2 5.1 2.7 5.3 0.4 2.7 5.9 2.3 19.4 9.4 0.0 7.8 7.7 8.4 1.1 0.2 1.5 0.0 15.8 0.0 0.0 9.9 4.0 0.0 0.6 6.1 0.7 1.3 0.1 6.2 0.0 0.0 0.0 2.8 1.1 9.9 2.9 0.3 4.8 0.2 2.9 23.0 0.0 6.1 4.3 1.5 2.2 2.0 7.9 1.6 1.0 6.6 1.3 6.4 2.3 0.0 0.0 0.0 0.0 0.8 33.2 2.1 0.0 0.0 28.5 0.0 2.1 0.0 0.0 2.3 0.8 2.8 0.3 0.3 5.8 1.3 5.9 0.8 27.0 1.2 0.9 0.0 0.0 2.1 12.8 8.3 0.1 7.1 7.7 0.0 8.4 0.2 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.6 1.1 3.9 3.2 0.0 1.5 3.4 5.3 1.5 4.7 3.3 2.5 6.5 1.4 5.6 5.3 0.0 0.6 0.0 2.8 19.1 0.0 0.8 0.0 1.4 1.2 0.0 0.0 0.1 1.7 1.6 0.7 6.0 1.3 0.0 0.0 0.0 4.3 1.7 10.4 0.0 5.5 0.0 1.2 1.3 8.8 0.6 9.8 6.0 5.0 1.0 1.7 0.0 1.1 2.8 13.8 0.1 0.2 0.0 3.4 0.5 0.1 7.9 0.0 0.0 2.9 10.5 PLA2G4B "cPLA2-beta, HsT16992" ENSG00000243708 "Phospholipase A2 group IVB" P0C869 15 41837775-41848147 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.0;skin 1: 32.8;tongue: 56.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1.9;Club cells: 2.3;Rod photoreceptor cells: 1.3" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebellum: 10.8" "Cell type enhanced" "Detected in some" "NK-cell: 3.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 11.0;T-47d: 5.9" NA NA "unprognostic (6.16e-2)" "unprognostic (6.48e-3)" "unprognostic (5.06e-3)" "unprognostic (1.27e-4)" "unprognostic (1.06e-1)" "unprognostic (2.56e-3)" "unprognostic (1.53e-1)" "unprognostic (2.27e-2)" "unprognostic (3.60e-2)" "unprognostic (1.90e-2)" "unprognostic (1.23e-2)" "unprognostic (5.14e-3)" "unprognostic (3.26e-5)" "unprognostic (4.36e-1)" "unprognostic (5.91e-2)" "unprognostic (1.22e-1)" "unprognostic (2.97e-2)" 1.8 1.2 1.8 1.8 2.2 3.4 3.6 10.8 2.1 6.1 1.8 1.8 1.8 1.9 2.7 2.3 19.3 2.0 1.9 1.8 1.8 2.5 2.5 2.6 2.2 3.3 1.8 1.8 4.2 3.5 1.4 3.2 1.8 1.8 4.8 1.1 1.8 7.0 2.7 1.8 32.8 2.4 1.8 1.8 3.0 1.8 1.8 1.8 2.2 4.8 56.0 36.0 2.0 5.9 3.0 0.5 0.2 0.8 3.9 1.5 0.1 1.3 0.7 0.0 0.0 0.1 0.0 3.7 0.4 1.2 1.3 0.1 0.3 0.7 0.3 0.1 0.7 0.1 4.4 1.5 0.5 0.3 0.0 2.5 1.1 1.4 3.4 1.7 0.2 1.4 0.9 4.9 0.2 1.3 0.1 0.6 1.9 1.7 0.2 0.4 2.1 1.0 4.1 1.0 5.5 1.2 0.0 1.2 0.9 1.0 11.0 0.2 1.1 0.0 2.0 1.0 0.9 5.9 1.8 0.0 0.0 1.0 1.0 0.1 3.4 0.0 0.9 0.3 5.0 0.0 0.0 0.8 0.0 1.5 0.5 0.9 0.1 0.4 0.8 0.5 3.0 0.9 0.8 0.2 3.9 0.2 0.5 1.2 0.1 1.8 2.2 10.8 2.1 1.8 2.5 1.8 1.8 1.8 1.8 0.0 1.9 0.0 0.2 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid metabolism, Phospholipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.8;skeletal muscle: 45.0" "Cell type enhanced" "Detected in many" 14 "Bipolar cells: 54.2;Cone photoreceptor cells: 62.8;Muller glia cells: 53.7;Rod photoreceptor cells: 133.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 8.2;HHSteC: 13.4;TIME: 18.6" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol NA NA Cytosol "HPA043083: AB_10795714" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (4.18e-2)" "unprognostic (2.82e-2)" "unprognostic (7.37e-2)" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (8.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.11e-3)" "unprognostic (1.90e-1)" "unprognostic (4.66e-2)" "unprognostic (9.45e-2)" "unprognostic (2.28e-3)" "unprognostic (1.87e-1)" "unprognostic (9.01e-2)" 4.0 11.7 8.9 4.2 23.2 0.4 3.0 12.9 14.5 3.4 3.5 23.4 2.0 5.1 6.8 5.2 3.6 4.3 4.6 18.5 10.0 10.0 4.4 3.8 5.9 7.2 31.8 8.5 2.0 4.1 14.8 4.6 4.1 16.9 5.7 2.9 5.4 3.1 6.7 45.0 4.9 6.7 8.1 18.6 8.1 2.4 2.4 17.1 0.7 3.3 7.5 4.3 4.9 2.1 5.4 2.0 0.0 7.9 1.5 0.8 2.0 0.7 1.1 0.0 0.3 5.2 3.0 0.1 1.3 8.2 1.2 3.5 0.0 2.1 0.0 1.8 3.2 2.6 0.2 0.0 0.2 2.0 0.8 0.1 0.0 0.3 1.2 13.4 0.0 1.8 0.6 0.3 0.5 5.4 2.5 5.1 0.0 0.0 7.4 2.0 2.0 0.0 0.1 0.1 0.9 0.1 0.1 1.8 0.7 2.5 0.4 0.8 0.1 1.5 2.6 6.3 4.2 0.7 1.8 18.6 2.3 0.7 2.5 0.9 0.5 1.4 0.2 1.6 0.0 4.4 0.0 3.2 0.0 0.2 7.9 0.6 5.4 0.8 0.0 2.0 1.6 0.0 0.0 0.0 1.5 2.0 1.4 0.2 2.0 8.9 23.2 12.9 14.5 10.0 10.0 31.8 8.5 16.9 17.1 3.0 1.7 0.5 0.8 2.5 54.2 30.9 10.2 0.0 0.0 0.0 62.8 0.1 1.7 7.7 0.2 16.9 1.6 0.0 2.5 0.2 3.8 1.7 0.0 1.0 5.0 31.8 0.0 3.1 0.3 0.0 0.6 2.8 6.8 4.6 1.5 53.7 4.1 0.3 7.4 3.4 133.4 12.9 11.8 0.3 0.5 2.6 0.1 0.0 0.0 0.1 PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094554 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "cervix, uterine: 35.6;prostate: 22.4;skin 1: 13.9;tongue: 11.6;vagina: 17.1" "Cell type enhanced" "Detected in some" 15 "Cone photoreceptor cells: 2.0;Glandular cells: 2.2;Rod photoreceptor cells: 1.0;Suprabasal keratinocytes: 3.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "RPMI-8226: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (2.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.33e-3)" "unprognostic (4.35e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-7)" "unprognostic (2.54e-2)" "unprognostic (2.34e-1)" "unprognostic (3.47e-2)" "unprognostic (4.32e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 35.6 0.1 0.1 0.1 0.0 1.4 0.3 1.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 22.4 0.0 0.1 0.6 0.1 0.1 13.9 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.4 0.1 11.6 1.2 0.6 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 19.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 3.0 0.0 0.0 0.0 0.3 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 19.9" "Cell type enhanced" "Detected in some" 27 "Alveolar cells type 2: 8.0;Basal keratinocytes: 16.1;Suprabasal keratinocytes: 39.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.4;HaCaT: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041105 Enhanced NA NA "HPA041105: AB_2677300" "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.2 16.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 39.3 0.0 0.0 0.0 0.5 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 30.4;skin 1: 48.1" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 2: 54.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 14.1;RT4: 10.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.1 0.1 0.0 2.5 0.3 0.3 1.8 0.0 0.1 4.5 11.0 0.0 4.7 4.2 0.4 9.7 10.4 0.2 3.1 1.0 0.0 0.0 10.8 0.2 30.4 0.1 0.0 0.0 0.1 0.1 0.7 4.1 0.3 0.0 3.3 2.5 0.0 5.3 2.8 8.6 48.1 12.3 1.1 0.1 0.2 1.6 0.1 0.0 6.2 1.6 14.9 3.4 2.2 6.3 0.6 0.3 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.4 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.1 0.0 14.1 0.1 0.0 0.0 0.1 0.0 10.6 0.6 0.1 0.0 1.1 0.0 0.1 1.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 54.9 0.0 3.3 4.8 0.0 3.2 0.0 0.0 0.0 5.2 0.0 1.5 3.3 0.2 0.0 0.0 12.0 0.0 1.2 0.7 0.2 2.7 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 4.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 1.0 0.0 4.3 1.6 PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091190 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.3;retina: 58.3" "Cell type enhanced" "Detected in some" 21 "Cardiomyocytes: 79.9;Cone photoreceptor cells: 66.8;Leydig cells: 75.4;Peritubular cells: 68.9;Sertoli cells: 258.7" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 23 "plasmacytoid DC: 2.3" "Lineage enriched" "Detected in single" 23 "dendritic cells: 2.3" "Cell line enhanced" "Detected in some" "EFO-21: 2.4;HaCaT: 1.1;hTEC/SVTERT24-B: 1.5;hTERT-RPE1: 1.4;U-138 MG: 3.1;U-2197: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053361 Approved "Secreted - unknown location" NA NA "HPA053361: AB_2682127" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" 2.6 0.5 2.8 2.0 6.7 0.2 1.9 1.9 5.2 0.3 10.5 2.1 2.5 1.2 0.5 2.1 5.7 1.9 3.0 48.3 2.6 2.4 0.2 1.8 3.2 1.0 6.1 2.0 17.3 1.2 0.2 0.1 8.3 6.8 6.9 3.2 58.3 1.0 10.3 0.4 0.4 1.0 19.3 1.0 0.8 2.3 3.3 1.3 0.0 0.7 0.0 1.7 7.3 2.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 3.1 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 2.8 6.7 1.9 5.2 2.6 2.4 6.1 2.0 6.8 1.3 0.0 0.3 0.0 0.0 0.3 9.3 79.9 0.0 0.0 0.0 0.0 66.8 0.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.1 2.1 1.5 0.0 0.0 0.2 0.0 0.0 8.6 0.8 3.6 75.4 0.0 0.0 0.0 0.0 25.1 0.0 0.0 68.9 0.0 27.8 258.7 2.4 0.5 0.6 0.4 0.2 0.0 0.0 0.0 PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38205690 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid metabolism, Phospholipid metabolism" "Calmodulin-binding, Hydrolase" "Disease mutation, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 23.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 31.8;HMC-1: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001171 Approved Approved "Centriolar satellite,Cytosol" NA NA "Centriolar satellite, Cytosol" "HPA001171: AB_1079145" "unprognostic (5.26e-2)" "prognostic favorable (7.29e-4)" "unprognostic (8.74e-2)" "unprognostic (6.27e-2)" "unprognostic (3.83e-1)" "unprognostic (3.70e-3)" "unprognostic (8.67e-3)" "unprognostic (9.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.91e-1)" "unprognostic (2.37e-3)" "unprognostic (4.95e-2)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "prognostic favorable (1.55e-4)" 16.2 17.7 15.6 8.5 20.5 13.1 15.6 15.9 26.3 14.8 7.9 36.9 18.5 9.8 16.3 20.5 8.7 21.6 25.3 6.3 19.7 7.2 18.1 8.6 9.0 12.4 19.3 16.7 21.3 12.8 24.2 12.7 6.8 19.5 17.6 6.3 12.9 20.2 17.4 7.4 18.1 8.7 7.8 14.9 12.1 9.5 30.0 23.2 16.3 45.7 4.1 11.3 12.1 11.2 1.8 5.4 4.1 0.9 8.8 5.7 1.9 0.7 2.8 3.0 7.8 10.1 5.0 8.2 0.9 1.0 0.8 1.1 3.1 1.8 5.9 6.6 2.3 1.3 3.6 3.5 1.9 1.0 9.0 13.2 31.8 3.9 3.6 2.8 3.5 20.3 16.3 4.3 2.8 4.5 8.2 1.0 13.0 5.2 10.7 1.5 4.6 6.6 2.1 2.6 2.1 1.8 4.9 1.2 4.5 2.9 7.0 5.8 2.4 1.3 3.1 7.2 4.5 3.3 2.5 1.3 2.6 4.5 1.1 0.6 17.6 3.1 3.1 3.7 4.1 1.6 4.1 0.9 0.4 3.8 0.3 1.9 1.8 3.1 5.7 1.5 1.5 1.4 3.9 3.3 8.8 0.6 5.4 3.7 1.9 15.6 20.5 15.9 26.3 19.7 7.2 19.3 16.7 19.5 23.2 3.0 2.4 4.4 3.6 2.7 9.4 1.5 2.5 5.3 5.7 12.2 3.9 2.5 0.0 1.4 16.1 1.9 11.0 0.0 0.9 2.4 2.1 4.2 0.0 3.4 1.4 14.3 10.9 3.7 1.5 13.7 5.5 1.0 1.7 3.6 6.9 4.5 1.4 11.5 3.5 0.8 7.0 6.5 1.7 23.8 7.5 3.0 4.1 6.9 6.9 1.3 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 57.0;lymphoid tissue: 32.9" "Cell type enriched" "Detected in some" 13 "Hofbauer cells: 332.5" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 24.2" "Group enriched" "Detected in many" 56 "dendritic cells: 7.9;monocytes: 24.2" "Cell line enhanced" "Detected in some" "GAMG: 2.2;NTERA-2: 3.9;PC-3: 7.9;RT4: 3.6;U-2 OS: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 170000000 "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 57.0 2.1 2.8 14.0 5.8 1.1 2.9 2.0 2.7 1.5 4.4 2.0 0.4 2.3 2.9 1.6 0.8 1.4 3.6 2.0 2.1 1.7 1.0 4.3 19.0 22.2 3.2 1.8 4.0 0.9 0.1 3.1 15.8 2.3 8.5 6.6 2.8 2.5 1.6 0.9 2.3 3.7 1.5 7.1 32.9 1.4 0.7 2.0 6.4 13.1 0.6 6.0 7.2 0.8 0.1 7.9 0.2 24.2 0.0 0.2 6.1 0.0 0.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 2.2 1.6 0.0 0.1 0.0 0.2 2.0 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 3.9 0.0 7.9 0.0 0.0 0.1 0.0 3.6 0.1 0.5 0.0 0.0 0.0 1.1 1.0 1.0 0.0 0.0 3.7 0.1 0.9 0.1 0.0 0.0 0.0 0.2 1.3 0.0 24.2 0.1 0.0 5.0 0.2 0.1 0.0 0.0 7.9 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 6.1 2.8 5.8 2.0 2.7 2.1 1.7 3.2 1.8 2.3 2.0 0.0 2.2 0.0 3.6 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.8 0.9 8.7 0.0 0.0 332.5 1.6 3.4 0.0 19.0 0.0 0.0 25.7 10.1 22.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 3.3 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42175233-42207724 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 132.2" "Cell type enhanced" "Detected in many" 22 "Basal glandular cells: 379.6;Glandular cells: 176.4;granulocytes: 158.4;Urothelial cells: 792.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 2.1;T-reg: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;T-cells: 2.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.9;HMC-1: 55.1;hTERT-RPE1: 61.0;LHCN-M2: 55.7;U-2197: 58.1;WM-115: 115.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 12000 "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 19.3 14.9 5.2 12.9 6.8 0.4 13.3 2.2 6.2 24.5 17.1 9.1 19.0 11.2 35.5 28.1 18.1 19.1 18.5 7.3 6.0 5.9 67.6 2.8 15.9 1.9 8.2 3.6 18.4 5.8 132.2 5.1 15.5 9.4 27.4 12.2 39.4 6.1 12.7 5.8 2.0 31.7 23.0 7.0 1.0 14.6 12.2 3.8 0.6 11.2 14.7 7.4 47.9 13.7 0.3 0.1 1.6 0.0 0.0 2.3 0.3 0.5 0.2 4.2 1.0 7.7 10.5 0.1 18.1 32.0 7.7 6.6 0.2 85.9 0.0 0.6 2.3 3.7 1.4 0.0 4.0 15.9 7.9 1.4 0.1 0.1 0.1 37.9 0.0 55.1 10.5 0.0 18.8 0.7 61.0 14.4 0.0 0.5 0.1 55.7 0.0 0.0 0.0 5.6 0.0 7.6 0.0 15.6 0.0 2.5 0.0 0.0 0.9 0.0 0.1 24.6 8.2 0.1 0.0 27.5 1.5 5.7 58.1 1.8 0.0 0.1 0.0 1.2 0.0 115.5 1.6 0.0 0.0 0.3 0.0 1.0 0.3 2.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.3 0.3 5.2 6.8 2.2 6.2 6.0 5.9 8.2 3.6 9.4 3.8 0.0 20.2 2.4 379.6 9.6 4.1 7.6 0.0 5.3 11.4 0.0 3.9 0.5 0.0 0.6 0.8 82.6 0.0 0.0 0.6 1.1 19.9 176.4 158.4 1.0 1.5 1.6 0.0 36.8 0.6 0.8 3.4 7.8 21.9 2.8 0.0 2.0 30.5 0.0 2.5 0.1 3.7 12.9 17.6 0.7 0.4 11.8 0.6 3.8 0.4 792.4 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917497 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 48.4" "Cell type enhanced" "Detected in many" 17 "Basal glandular cells: 550.8;Pancreatic endocrine cells: 366.2;Urothelial cells: 779.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 2.4;neutrophil: 4.5;plasmacytoid DC: 4.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.5;granulocytes: 4.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 70.3;LHCN-M2: 67.8;RPTEC TERT1: 257.8;U-251 MG: 69.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported "Secreted to blood" NA NA 647000 58000 "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 26.7 2.4 1.0 15.5 2.1 11.3 9.7 1.6 1.5 6.9 5.8 2.9 4.9 3.8 10.7 21.2 9.1 6.5 10.7 14.3 1.3 1.0 23.3 2.3 23.4 5.5 1.6 1.5 6.8 3.7 3.6 1.8 48.4 3.1 7.5 6.7 4.5 10.6 5.0 12.2 9.0 8.1 8.4 2.5 23.8 7.8 5.8 1.3 4.8 10.9 11.6 8.2 16.3 9.3 0.1 4.5 4.5 0.4 0.0 0.0 0.3 13.3 7.1 3.0 0.1 0.2 5.1 0.1 8.1 37.9 3.3 5.2 0.1 70.3 0.0 15.0 1.1 35.0 9.2 0.0 13.5 3.8 0.7 0.0 0.0 0.3 0.1 6.2 1.2 2.6 13.5 1.6 22.6 8.7 37.6 9.4 0.0 0.0 0.0 67.8 0.0 0.0 1.7 0.8 0.0 18.7 0.0 9.2 0.0 257.8 10.5 0.0 0.0 0.0 0.3 0.2 2.2 0.0 1.8 23.8 0.2 1.7 1.7 69.2 0.0 0.1 0.1 18.2 2.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 4.5 0.0 0.0 4.5 0.0 0.3 1.0 2.1 1.6 1.5 1.3 1.0 1.6 1.5 3.1 1.3 3.0 5.8 0.5 550.8 33.2 0.0 2.4 0.0 1.4 10.3 27.9 0.0 17.1 58.0 65.4 0.5 11.7 0.0 0.0 18.1 16.5 18.1 169.7 31.1 0.0 38.5 0.0 3.4 6.2 3.9 0.0 2.3 31.5 6.8 41.5 0.0 0.0 366.2 0.0 0.0 0.7 0.0 6.5 25.9 0.0 0.1 25.7 14.6 0.5 0.9 779.6 PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28643788 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 66.7" "Group enriched" "Detected in many" 7 "Early spermatids: 22.5;Extravillous trophoblasts: 20.1;granulocytes: 5.7;Hofbauer cells: 10.2;Kupffer cells: 12.3;Late spermatids: 11.8;Macrophages: 8.7;Syncytiotrophoblasts: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 14 "classical monocyte: 3.1;eosinophil: 3.3;intermediate monocyte: 4.9;myeloid DC: 6.4;neutrophil: 9.9;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 40 "dendritic cells: 6.4;granulocytes: 9.9;monocytes: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 5.8;OE19: 12.0;RT4: 4.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" NA NA "unprognostic (2.18e-2)" "unprognostic (2.49e-1)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-3)" "unprognostic (4.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (2.61e-9)" "unprognostic (2.48e-2)" "unprognostic (2.19e-2)" "unprognostic (4.99e-2)" "unprognostic (8.03e-2)" 0.9 3.3 0.7 1.0 2.1 2.9 1.0 0.6 0.7 0.9 0.8 0.6 0.6 0.2 0.8 1.7 1.3 0.7 0.9 1.4 0.6 0.9 0.8 0.6 0.7 0.6 0.8 0.6 0.6 0.6 0.0 0.7 1.3 0.7 1.0 1.1 0.7 0.6 0.9 0.9 5.2 66.7 1.7 0.8 2.8 0.5 1.2 0.6 0.6 1.2 0.9 0.6 0.9 0.6 0.0 6.4 9.9 5.2 0.0 0.1 1.1 0.6 0.1 3.8 0.1 0.8 0.6 5.8 0.1 1.5 0.4 0.3 3.8 0.4 0.4 0.4 0.6 1.7 0.8 0.0 3.1 0.3 0.2 0.0 0.3 0.6 0.7 1.3 0.7 0.3 0.6 1.8 0.6 1.0 0.7 1.0 0.0 0.0 0.1 1.1 0.0 0.0 0.5 0.1 12.0 0.8 0.0 0.6 0.0 1.7 4.3 1.7 0.3 0.1 0.2 0.3 0.3 0.0 2.0 0.4 0.4 1.1 0.2 0.2 0.8 0.2 0.0 1.3 2.9 0.1 0.0 3.1 3.3 0.0 4.9 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 9.9 0.0 5.2 0.3 0.1 1.1 0.7 2.1 0.6 0.7 0.6 0.9 0.8 0.6 0.7 0.6 0.0 1.1 0.0 0.8 0.3 0.0 1.1 0.0 0.0 1.2 0.0 0.0 0.4 1.7 0.9 22.5 0.3 1.7 0.0 0.8 20.1 0.5 0.3 5.7 0.0 10.2 0.0 1.2 0.6 12.3 11.8 1.1 8.7 0.0 0.0 1.1 0.6 0.9 0.2 0.7 0.0 0.0 0.0 0.0 0.9 0.2 0.4 6.9 0.5 0.3 1.4 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 56.7" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 29.3;Distal tubular cells: 28.2;Endothelial cells: 30.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 22.0;Hep G2: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" NA NA 5400 "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: AB_2674311, HPA057910: AB_2683552" "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 5.6 7.0 13.8 4.4 27.7 3.4 5.9 7.5 31.1 6.5 9.9 2.1 20.6 5.5 8.0 10.3 4.5 7.4 6.6 8.6 15.7 9.1 10.0 3.1 4.0 1.6 9.3 14.5 3.2 10.8 56.7 4.6 14.2 5.5 10.4 3.6 1.3 19.7 22.2 9.8 2.3 4.5 12.3 4.0 2.9 5.5 2.6 8.0 4.1 3.1 1.9 1.1 8.6 6.3 0.5 0.8 2.8 3.3 2.4 5.2 0.4 0.0 0.6 2.3 0.1 4.3 8.3 3.2 9.8 6.5 2.6 1.6 22.0 2.4 1.0 4.1 1.9 0.1 0.0 1.8 0.0 1.9 0.0 2.1 0.4 1.6 33.1 1.1 0.5 0.3 0.5 0.4 3.5 0.0 3.3 5.2 6.3 3.3 12.9 0.0 2.9 0.5 1.6 7.4 5.1 3.6 7.0 0.0 5.8 2.0 8.1 8.5 3.6 0.0 2.0 0.4 8.9 9.8 3.2 0.9 8.5 3.8 0.6 6.1 9.7 11.2 16.6 4.3 6.1 14.5 0.8 3.3 2.8 3.6 0.7 5.2 0.2 1.0 1.3 0.4 0.5 0.5 1.1 2.1 2.4 0.4 0.8 0.2 0.4 13.8 27.7 7.5 30.8 15.7 9.1 9.3 14.5 5.5 8.0 0.0 4.3 0.8 17.4 1.6 0.8 29.3 5.1 16.0 3.4 15.7 0.0 1.9 28.2 0.9 7.6 30.5 0.3 0.0 11.3 1.9 7.9 21.8 1.1 2.1 0.7 1.6 0.0 21.5 4.6 3.1 3.1 2.5 6.8 1.0 1.9 16.3 2.4 0.0 3.5 7.9 3.7 0.0 13.0 3.1 4.3 1.5 1.5 5.1 1.2 16.2 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 30.5;lymphoid tissue: 36.3" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 25.1;granulocytes: 25.5;Hofbauer cells: 26.0;Kupffer cells: 49.0;Macrophages: 28.1;T-cells: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 31.5;HMC-1: 39.3;THP-1: 11.4;U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 6.3 3.6 8.1 17.6 11.6 30.5 2.9 1.1 7.5 2.9 3.3 16.2 1.7 4.0 2.8 3.2 2.4 4.6 6.5 3.3 6.9 5.1 3.3 4.2 12.5 17.2 12.7 2.4 1.6 2.0 1.3 2.9 4.6 9.3 3.2 5.5 4.1 5.2 2.9 1.3 1.5 10.2 4.8 17.9 36.3 3.6 1.4 10.9 12.2 2.8 1.8 17.6 6.9 2.5 1.0 4.5 8.5 4.3 1.8 3.1 2.0 0.1 0.0 0.2 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.8 0.6 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.0 6.7 39.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.3 1.7 0.0 0.0 1.8 3.6 0.4 0.0 0.1 5.5 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.3 0.0 11.4 4.1 0.0 3.8 0.0 0.0 0.0 0.0 1.5 0.0 21.6 0.0 2.7 4.2 8.5 3.1 4.3 2.0 0.7 1.6 1.6 4.5 1.0 1.6 1.8 6.9 1.8 4.2 1.6 2.9 2.0 8.1 11.6 1.1 7.5 6.9 5.1 12.7 2.4 9.3 10.9 6.0 25.1 3.4 0.1 0.8 0.0 2.8 2.5 6.7 5.7 1.8 0.0 0.4 0.0 0.1 1.0 0.4 0.0 0.0 0.0 0.4 1.0 0.0 25.5 0.2 26.0 0.0 0.0 1.8 49.0 0.4 0.3 28.1 3.3 0.0 0.8 0.0 0.2 0.0 0.0 0.7 0.2 0.0 0.3 0.2 2.1 0.5 0.3 15.9 1.2 0.0 PLCB3 ENSG00000149782 "Phospholipase C beta 3" Q01970 11 64251523-64269150 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "intestine: 77.5" "Cell type enhanced" "Detected in many" 6 "Enterocytes: 54.0;Mucus-secreting cells: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 4.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009257, HPA039279, HPA043907" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 94000 "Nucleoplasm, Golgi apparatus" "CAB009257: AB_654079, HPA039279: AB_2676425, HPA043907: AB_2678726" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "unprognostic (2.86e-1)" "unprognostic (2.35e-1)" "unprognostic (9.35e-2)" "unprognostic (6.23e-3)" "prognostic unfavorable (1.39e-4)" "unprognostic (2.44e-2)" "unprognostic (6.61e-2)" "unprognostic (1.26e-1)" "unprognostic (8.07e-3)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.31e-5)" "unprognostic (5.04e-3)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (3.88e-2)" 5.8 9.7 6.1 7.0 5.4 3.7 10.9 6.3 5.8 8.6 40.6 3.1 8.8 59.3 9.1 5.9 16.8 7.7 11.8 4.8 5.4 2.6 5.5 3.2 9.1 4.8 3.5 2.2 11.0 4.0 7.6 2.9 11.1 4.8 6.4 7.0 5.0 6.5 6.3 3.8 10.7 77.5 7.0 4.5 7.2 8.0 4.6 5.4 4.2 5.0 8.2 9.3 6.3 8.8 0.3 4.4 0.9 1.4 0.3 0.8 0.4 17.8 10.0 9.9 14.7 10.4 8.0 9.9 14.2 10.8 12.2 7.4 8.8 13.6 1.2 8.6 17.8 10.5 30.8 11.1 13.3 4.2 8.5 6.1 13.9 20.6 6.6 7.2 3.3 9.2 6.7 8.9 13.2 9.8 13.4 17.7 5.4 6.8 1.5 15.4 21.5 4.2 7.0 16.0 22.7 11.0 9.3 22.3 5.2 7.5 18.9 2.6 10.9 21.0 26.5 10.1 6.4 13.9 6.5 30.7 11.3 13.5 25.8 9.1 1.9 0.9 1.4 18.7 8.0 10.4 0.0 1.4 0.2 0.7 1.4 0.8 0.1 0.8 0.7 1.3 0.3 0.4 0.4 0.9 0.3 1.4 4.4 0.2 0.4 6.1 5.4 6.3 5.8 5.4 2.6 3.5 2.2 4.8 5.4 3.0 9.3 0.0 5.1 11.6 1.0 2.6 10.2 0.0 3.4 15.7 0.0 7.8 1.7 6.2 0.9 7.3 54.0 0.0 6.7 14.6 9.3 5.1 5.7 2.6 9.0 3.2 2.4 19.6 12.7 1.1 9.2 11.0 8.5 29.7 41.8 4.3 12.8 23.0 11.7 3.3 0.7 25.8 7.2 2.6 8.7 10.3 12.2 1.3 31.0 7.2 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.9;retina: 40.2;salivary gland: 39.8" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 79.8;Cardiomyocytes: 57.6;Ciliated cells: 56.2;Horizontal cells: 155.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Group enriched" "Detected in all" 4 "cerebellum: 44.9;pons and medulla: 11.9" "Cell type enriched" "Detected in single" 20 "plasmacytoid DC: 6.6" "Lineage enriched" "Detected in single" 20 "dendritic cells: 6.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 38.2;hTERT-HME1: 18.7;LHCN-M2: 30.8;OE19: 17.8;RPTEC TERT1: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules NA NA Microtubules Nucleoplasm "HPA007951: AB_2667944" "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 5.5 5.0 2.1 4.5 4.6 0.2 5.6 44.9 5.2 6.0 13.1 2.7 2.4 1.6 12.3 16.2 6.9 10.9 6.2 12.4 2.3 6.6 2.3 0.9 4.4 1.0 4.0 3.3 2.9 1.3 0.5 15.1 4.4 11.9 6.9 12.6 40.2 39.8 7.1 2.5 4.3 3.1 12.3 3.1 1.1 9.7 2.1 2.4 4.3 21.9 4.4 2.0 7.1 8.8 0.0 6.6 0.0 0.0 0.3 0.0 0.0 0.0 6.1 3.1 0.0 0.0 0.1 0.0 13.4 3.8 4.0 2.5 1.2 0.9 0.0 0.2 38.2 14.5 0.0 0.9 2.9 6.0 0.0 1.8 1.6 2.2 0.0 0.6 0.0 0.0 0.9 1.2 5.2 18.7 7.3 0.0 0.0 1.5 0.1 30.8 2.0 0.0 0.0 3.3 17.8 3.9 0.0 0.0 0.2 39.4 2.8 10.2 7.1 0.0 9.2 5.6 4.3 7.8 0.0 0.1 4.3 0.3 0.4 5.2 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 0.0 2.1 4.6 44.9 5.2 2.3 6.6 4.0 3.3 11.9 2.4 6.0 0.3 0.0 3.6 2.2 79.8 57.6 0.0 56.2 11.4 5.2 0.0 0.0 0.0 0.5 1.0 35.4 2.3 0.0 0.2 0.0 4.8 10.1 0.0 0.0 0.1 155.7 40.4 1.3 0.0 0.4 1.4 0.3 6.8 1.0 35.3 1.9 5.0 7.0 19.4 0.6 5.4 12.9 23.6 1.4 1.3 0.9 0.1 0.0 34.0 1.8 PLCD1 ENSG00000187091 "Phospholipase C delta 1" P51178 3 38007496-38029762 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 14.3;fHDF/TERT166: 15.8;hTCEpi: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009913, HPA020107, HPA021677" Approved Approved Microtubules NA NA Microtubules "CAB009913: AB_2163388, HPA020107: AB_1855318, HPA021677: AB_1855319" "unprognostic (1.75e-3)" "unprognostic (1.01e-2)" "unprognostic (4.29e-2)" "unprognostic (1.45e-2)" "unprognostic (3.44e-1)" "unprognostic (9.67e-3)" "unprognostic (1.55e-1)" "unprognostic (7.25e-3)" "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.25e-11)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (2.93e-1)" "unprognostic (7.88e-2)" 10.9 11.3 11.2 5.6 12.1 5.1 8.0 6.0 11.2 11.6 19.3 15.2 7.3 6.6 9.1 7.6 21.9 8.6 8.5 8.0 13.0 6.9 7.8 5.8 9.4 9.3 10.5 11.4 12.8 6.2 4.7 7.3 6.9 15.9 10.6 12.7 8.3 10.9 12.6 4.5 17.0 6.5 12.3 15.5 6.3 6.5 37.3 8.7 7.7 6.6 21.2 12.2 14.6 23.1 1.0 2.6 8.6 2.4 3.7 13.2 5.4 0.6 1.7 5.7 1.6 16.0 14.3 1.8 1.7 6.9 2.7 4.1 0.6 1.4 0.4 0.9 15.8 1.7 9.1 3.0 1.8 0.8 2.5 0.7 0.2 0.9 2.9 9.4 0.0 1.0 11.6 19.6 7.9 1.1 5.9 5.0 1.4 9.6 0.8 5.9 0.7 1.3 0.6 1.5 3.3 1.7 0.5 0.8 2.2 3.1 3.1 0.0 1.6 0.5 7.7 1.9 1.9 1.6 0.7 2.9 1.6 4.1 4.2 0.0 3.5 1.4 0.3 4.1 0.0 0.9 8.6 1.9 0.1 10.2 2.4 11.6 1.0 13.2 9.8 2.6 0.5 7.8 6.1 6.9 3.7 1.4 1.5 11.8 5.4 11.2 12.1 6.0 10.7 13.0 6.9 10.5 11.4 15.9 8.7 3.0 6.9 1.4 11.2 2.5 1.0 3.8 10.2 0.0 4.5 8.7 2.0 1.5 3.3 9.2 1.4 7.4 48.4 0.0 2.6 3.8 6.6 12.4 4.6 3.8 3.5 3.2 4.7 19.6 3.5 2.5 11.8 5.1 1.7 3.6 23.8 14.2 3.3 15.9 13.4 5.0 1.4 6.5 9.1 2.6 3.2 5.1 0.7 8.2 9.4 15.0 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108967-45133354 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 63.6" "Cell type enhanced" "Detected in many" 11 "Enterocytes: 138.0;Paneth cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 5.7 12.0 10.1 4.8 16.5 2.4 6.6 12.2 12.9 5.0 24.9 14.0 2.8 2.9 6.3 6.4 8.9 5.8 9.4 13.1 11.6 6.6 3.6 1.2 4.5 1.7 13.9 11.4 9.9 2.7 1.5 3.0 5.7 19.5 5.8 13.7 10.3 4.7 5.7 63.6 9.9 2.8 12.9 15.0 2.0 17.9 5.4 14.6 0.0 2.3 20.1 2.8 17.5 10.5 1.3 0.9 2.9 1.5 1.3 0.9 0.5 8.4 21.1 1.5 3.1 2.3 5.0 10.7 4.6 10.4 4.3 4.1 5.1 15.5 0.3 16.7 10.8 3.5 19.3 2.4 19.9 1.7 4.2 7.9 0.3 22.2 6.6 11.9 0.4 1.2 5.4 8.0 3.9 5.3 11.0 2.6 0.9 1.8 0.6 4.6 13.2 1.3 1.9 1.8 40.6 20.8 3.0 3.5 0.5 13.6 16.9 0.4 2.7 5.0 8.4 4.5 3.4 17.9 0.9 5.3 2.7 14.8 3.5 5.4 0.8 0.9 0.6 4.4 0.5 2.1 2.3 1.5 2.4 0.9 1.5 0.6 1.0 0.7 0.6 0.5 1.3 0.9 0.8 2.9 1.3 0.3 0.9 0.6 0.5 10.1 16.5 12.2 11.5 11.6 6.6 13.9 11.4 19.5 14.6 11.9 2.2 0.0 10.9 6.8 27.2 23.8 12.7 1.4 2.3 7.0 23.6 2.5 1.7 7.0 12.5 9.2 138.0 0.0 2.9 7.2 8.2 9.8 1.1 0.4 1.5 6.4 4.7 8.6 0.3 3.6 18.4 0.3 3.3 1.0 13.0 6.8 18.3 62.6 31.1 1.7 37.9 6.5 4.2 1.9 6.6 5.0 6.1 0.0 26.3 40.1 PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607765-218637184 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 23.0;skeletal muscle: 62.5;smooth muscle: 33.1" "Group enriched" "Detected in some" 8 "Bipolar cells: 81.4;Cone photoreceptor cells: 231.7;Rod photoreceptor cells: 181.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SH-SY5Y: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009914, HPA038139, HPA038140" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA Cytosol "Endoplasmic reticulum, Plasma membrane" "CAB009914: AB_2252306, HPA038139: AB_2675855, HPA038140: AB_2675856" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (5.65e-5)" "unprognostic (7.77e-2)" "unprognostic (1.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.86e-2)" "unprognostic (3.15e-1)" "unprognostic (8.87e-3)" "unprognostic (7.54e-5)" "unprognostic (3.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (6.32e-2)" "unprognostic (8.46e-3)" "unprognostic (3.09e-1)" 1.1 2.5 1.5 1.0 1.6 0.5 1.0 0.9 2.4 0.6 6.4 0.3 3.8 0.9 0.8 1.1 3.7 0.6 0.9 0.9 1.0 1.5 3.9 0.5 0.7 0.7 1.6 1.0 0.7 0.4 1.4 4.7 0.6 2.6 6.4 1.5 23.0 1.4 0.6 62.5 0.8 1.4 33.1 1.1 0.5 3.5 3.9 0.5 0.0 1.4 6.8 0.5 9.6 5.3 0.9 1.2 0.3 0.4 0.9 0.9 1.0 0.6 1.6 2.2 0.4 0.2 1.4 1.2 1.2 2.6 0.4 1.4 2.4 0.3 1.4 1.8 0.4 1.0 1.0 0.0 1.5 0.3 0.5 1.8 1.2 3.6 1.9 0.2 1.2 0.6 3.0 0.1 2.0 0.5 4.8 2.8 0.8 1.0 1.1 2.3 1.8 0.4 1.2 0.7 0.2 3.4 0.9 0.8 0.5 4.4 3.0 2.3 21.5 1.0 0.8 0.3 1.3 2.6 0.5 6.1 1.6 1.2 0.7 0.7 0.5 0.8 0.9 4.7 0.3 1.6 0.0 0.4 0.0 0.5 0.0 0.1 0.0 0.3 0.9 0.3 0.9 0.7 0.8 0.3 0.9 0.0 1.2 0.7 1.0 1.5 1.6 0.9 2.4 1.0 1.5 1.6 1.0 2.6 0.5 0.0 1.4 0.0 0.2 0.5 81.4 0.8 0.0 0.0 0.0 0.0 231.7 0.1 0.0 0.2 14.2 1.1 0.0 0.0 0.0 12.6 0.6 0.0 0.0 0.0 0.5 7.9 0.0 0.0 0.0 22.0 0.3 0.0 0.0 0.0 0.0 8.8 0.4 0.0 0.0 1.4 181.4 0.0 1.4 2.2 0.8 0.1 0.7 0.0 0.0 0.1 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 94030812-94332823 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.6" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 1: 65.5;Enterocytes: 45.9;Muller glia cells: 98.6;Paneth cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.2 2.4 4.1 9.1 5.5 0.0 2.2 1.8 7.9 9.2 13.8 3.1 1.6 5.0 11.4 4.6 4.5 4.2 3.8 12.8 4.1 2.6 6.3 0.7 7.2 0.4 2.4 6.8 3.2 12.8 0.1 5.2 3.1 6.4 3.3 12.6 44.6 2.1 7.7 4.3 0.7 4.6 5.8 2.4 5.8 8.7 1.7 2.3 0.0 15.1 7.3 1.1 7.9 5.4 3.2 1.2 0.8 0.9 1.1 2.3 0.5 5.8 8.1 1.7 0.9 0.9 5.7 2.3 3.6 1.0 0.8 1.1 5.2 1.4 0.6 1.8 2.9 2.9 2.5 4.1 1.0 1.3 0.3 2.0 0.4 4.4 0.4 0.1 0.7 0.3 2.3 0.0 2.2 0.0 9.7 0.0 0.3 0.4 0.3 7.0 0.2 0.6 0.8 0.6 11.0 8.4 0.1 5.5 0.2 0.2 18.2 0.8 1.4 4.2 5.8 0.5 7.9 4.9 0.5 0.5 3.7 10.9 2.3 4.7 0.5 0.2 0.3 3.0 1.0 3.3 0.4 0.5 0.1 1.5 0.9 1.3 2.6 1.6 1.1 0.6 3.2 2.3 1.8 0.8 1.1 0.8 1.2 0.6 0.5 4.1 5.5 1.8 7.9 4.1 2.6 2.4 6.8 6.4 2.3 65.5 4.8 9.3 7.4 7.2 11.5 32.3 0.0 10.7 13.6 0.0 0.0 3.2 1.7 1.3 15.0 7.4 45.9 0.0 5.7 2.0 7.3 2.9 0.0 1.1 0.6 6.4 1.7 6.2 0.6 3.4 11.2 1.4 6.8 1.0 6.4 98.6 3.2 46.7 21.9 2.1 19.4 6.5 19.4 3.5 7.8 6.5 1.6 4.3 28.0 6.0 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 5.9;MAIT T-cell: 8.0;memory CD4 T-cell: 5.2;memory CD8 T-cell: 4.9;naive CD4 T-cell: 5.7;naive CD8 T-cell: 5.4;NK-cell: 4.0;T-reg: 4.4" "Group enriched" "Detected in many" 8 "NK-cells: 4.0;T-cells: 8.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol NA NA Cytosol "CAB004277: AB_628119, HPA036681: AB_2675245, HPA036682: AB_2675246" "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favorable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 20.2 15.1 25.1 20.9 22.1 8.3 34.9 52.6 26.8 19.9 13.9 23.4 12.5 16.5 27.6 13.9 13.5 17.0 18.7 20.9 25.4 13.6 15.3 6.8 19.3 30.7 18.5 20.5 28.7 9.1 16.9 14.2 22.2 18.7 18.4 13.2 20.0 13.2 20.6 13.4 22.3 17.1 22.2 15.4 20.1 12.4 19.9 23.9 48.1 28.5 11.9 21.9 17.1 21.1 0.7 0.0 0.0 0.0 4.0 8.0 3.3 5.4 6.9 33.2 24.3 13.3 9.3 10.6 8.9 11.5 18.0 15.3 16.6 1.8 12.1 11.0 9.7 18.9 10.1 14.4 16.0 10.5 3.4 7.7 0.8 11.5 19.5 10.1 4.7 3.3 11.9 9.0 13.3 10.4 16.3 20.0 26.0 9.0 8.0 16.2 40.4 29.2 3.7 12.3 7.0 12.7 23.3 24.2 5.9 9.9 10.0 11.8 22.5 16.0 7.5 16.0 19.4 8.7 5.6 21.6 43.1 14.0 13.7 10.8 8.9 3.9 10.0 10.2 5.2 17.8 0.0 0.0 0.0 5.9 0.0 8.0 0.3 5.2 4.9 0.0 0.7 5.7 5.4 0.0 4.0 0.0 0.0 4.4 3.3 25.1 22.1 52.6 26.8 25.4 13.6 18.5 20.5 18.7 23.9 14.9 6.5 0.8 1.8 4.9 3.7 9.2 0.0 1.4 3.4 3.5 9.8 1.3 0.0 2.7 5.1 15.8 6.4 0.0 1.4 1.6 6.1 1.9 1.1 2.5 3.2 3.2 1.7 13.5 2.2 5.3 14.1 1.7 3.3 1.0 9.8 7.2 2.8 3.7 17.3 2.4 4.6 12.9 5.1 11.6 11.5 6.0 0.7 6.9 5.1 0.9 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962693 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 211.5;Muller glia cells: 142.4;Rod photoreceptor cells: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 40.5;HMC-1: 19.4;REH: 16.5;U-698: 90.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 21000 "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 8.4 3.8 3.3 55.8 4.9 14.1 10.7 1.0 2.4 5.6 10.3 5.3 3.1 8.7 11.2 12.2 6.0 4.7 10.1 4.4 3.3 2.8 20.6 8.8 10.7 35.5 5.2 1.8 2.0 3.6 1.0 1.8 4.1 4.5 4.3 3.6 4.6 8.8 2.8 2.0 4.1 17.6 4.6 8.6 33.6 4.2 2.3 4.2 6.3 5.3 2.6 44.6 7.5 7.7 18.8 3.9 26.8 12.2 14.0 1.1 2.3 0.3 0.7 0.1 0.6 0.0 0.0 0.9 0.0 0.1 0.5 0.2 0.2 1.8 40.5 6.9 0.0 1.7 0.9 0.9 0.1 0.3 0.3 0.4 4.8 0.0 0.0 0.3 4.8 19.4 0.0 0.4 0.3 0.2 0.0 0.9 1.8 0.5 3.4 0.1 1.2 0.5 12.1 0.7 0.5 0.2 16.5 0.0 5.2 0.1 0.8 0.3 0.1 1.1 0.3 0.3 0.9 0.7 15.0 0.2 0.0 0.7 0.1 0.1 8.1 13.2 90.0 0.0 6.7 0.3 2.8 4.4 26.8 0.7 5.7 0.3 18.8 0.2 1.1 3.9 17.3 0.3 0.8 24.8 14.0 12.2 2.6 0.1 2.3 3.3 4.9 1.0 2.4 3.3 2.8 5.2 1.8 4.5 4.2 11.9 81.1 49.9 1.4 2.6 211.5 5.2 40.8 10.7 21.6 15.7 98.2 11.2 11.6 2.3 17.0 11.7 1.0 70.0 0.0 1.8 5.8 2.7 38.3 37.2 23.7 95.3 20.6 36.2 45.8 26.9 10.3 15.6 8.5 7.2 0.4 142.4 0.1 5.8 4.6 4.5 205.4 6.5 2.3 4.4 2.9 1.9 9.3 26.2 1.2 4.8 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745067 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.7;testis: 15.8" "Cell type enriched" "Detected in many" 6 "Early spermatids: 148.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 8.4;AF22: 27.2;NTERA-2: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.3 0.3 3.9 0.7 14.1 0.5 3.9 7.4 14.7 2.1 3.9 5.7 4.1 3.9 1.4 12.9 0.5 12.4 2.4 2.5 4.5 3.6 2.1 0.4 6.1 0.3 3.4 7.3 0.5 2.5 0.8 3.2 0.8 6.5 0.8 3.9 5.6 2.3 3.4 0.6 0.5 3.9 0.5 1.9 0.3 5.8 15.8 2.9 0.0 8.9 0.0 0.4 1.3 0.4 0.1 0.3 0.7 0.0 0.0 1.2 0.9 0.0 8.4 27.2 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.6 6.7 0.0 0.6 0.0 0.1 0.0 4.8 0.0 0.0 0.0 2.5 6.8 0.0 0.9 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.2 0.0 0.0 2.9 1.6 6.2 14.5 0.9 1.1 0.6 0.0 0.0 1.7 0.1 2.5 0.6 0.0 6.5 0.0 4.2 2.9 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.9 3.9 14.1 7.4 14.7 4.5 3.6 3.4 7.3 6.5 2.9 3.0 12.8 0.0 0.3 0.0 10.0 0.5 7.6 25.4 3.4 1.8 3.9 0.0 0.0 1.9 148.2 0.1 2.4 0.0 2.0 0.2 0.0 0.1 0.0 0.0 0.2 23.8 2.9 0.0 0.3 10.0 1.1 0.0 0.0 0.0 4.3 19.3 1.5 2.9 0.4 1.9 3.0 0.0 0.0 2.1 1.1 0.1 0.0 0.0 4.7 0.1 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505530 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;retina: 28.6;skin 1: 36.6" "Cell type enhanced" "Detected in many" 18 "Bipolar cells: 76.1;Cone photoreceptor cells: 70.7;Rod photoreceptor cells: 155.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 2.4" "Group enriched" "Detected in some" 4 "HBEC3-KT: 50.7;hTCEpi: 23.9;hTERT-HME1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "HPA072705: AB_2732211" "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.5 1.2 6.4 2.9 9.1 1.4 3.1 32.0 25.1 3.2 0.9 1.6 0.5 1.6 0.3 1.7 9.7 2.5 2.4 0.3 20.2 2.7 0.8 0.8 1.2 4.0 2.6 8.4 0.2 1.7 0.1 3.0 0.4 2.6 6.7 0.7 28.6 8.6 4.9 0.2 36.6 2.0 0.2 6.4 4.0 1.7 0.8 2.0 0.2 1.2 0.2 4.9 8.3 6.4 0.3 0.1 0.0 0.0 2.9 2.4 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 7.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.0 14.3 0.0 0.0 0.0 0.0 1.2 0.1 0.4 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.1 2.8 5.7 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.9 0.3 1.5 1.4 0.0 0.3 1.1 0.7 0.0 2.9 0.0 0.1 2.1 0.9 6.4 9.1 32.0 25.1 20.2 2.7 2.6 8.4 2.6 2.0 0.0 1.7 2.0 13.5 13.7 76.1 3.2 5.1 1.4 4.5 0.0 70.7 0.0 1.7 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.5 4.9 0.0 0.0 0.1 25.4 1.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 1.4 12.3 0.2 0.0 0.0 16.6 155.3 0.0 0.9 0.1 0.2 12.8 0.0 6.9 0.4 6.7 PLCZ1 "NYD-SP27, PLCzeta" ENSG00000139151 "Phospholipase C zeta 1" Q86YW0 12 18683169-18738057 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Fertilization, Lipid degradation, Lipid metabolism" "Developmental protein, Hydrolase, Transducer" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 29.5" "Group enriched" "Detected in some" 91 "Early spermatids: 451.0;Late spermatids: 242.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.8;hTERT-HME1: 1.4;NTERA-2: 2.1;U-2 OS: 1.2;U-251 MG: 1.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-2)" "unprognostic (1.39e-2)" "unprognostic (1.25e-2)" "unprognostic (1.59e-1)" "unprognostic (1.40e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.3 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 1.4 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.7 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 451.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 242.6 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.0 0.0 3.8 1.3 0.0 0.0 0.0 0.0 0.0 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600405-171810950 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 52.1" "Cell type enhanced" "Detected in many" 6 "Cholangiocytes: 50.9;Proximal tubular cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 30.3;SK-MEL-30: 16.9;TIME: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004527, HPA042396" Enhanced NA NA "CAB004527: AB_677324, HPA042396: AB_2677977" "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.0 26.6 5.3 6.1 20.4 4.5 6.3 1.4 10.8 8.6 19.7 31.4 1.8 27.7 6.9 4.9 25.0 4.9 52.1 14.7 7.7 4.7 7.5 20.2 4.4 5.2 25.3 7.2 17.1 13.9 0.9 2.7 6.6 18.8 3.5 9.4 8.5 13.2 4.2 2.0 17.6 29.5 3.4 16.8 9.9 5.3 3.5 21.8 0.9 4.1 10.7 8.5 4.3 11.5 0.1 0.9 10.2 2.6 3.0 4.1 0.8 2.3 3.7 1.9 0.7 6.0 6.8 4.1 1.2 5.3 1.9 2.3 0.5 3.4 0.0 9.5 0.5 13.1 7.9 0.3 1.0 3.0 1.9 1.6 2.2 5.9 13.2 2.7 3.8 10.5 2.6 5.8 2.2 1.1 5.4 30.3 0.6 1.4 0.0 0.4 0.6 0.0 3.2 0.4 6.0 2.7 0.1 0.8 0.0 4.7 0.9 0.0 0.0 4.1 2.5 16.9 2.8 4.7 5.0 26.3 0.8 3.2 2.1 1.3 5.1 4.1 0.0 3.7 4.6 1.0 10.2 2.6 3.2 0.5 1.6 4.1 0.0 0.4 1.0 0.9 0.1 0.0 0.1 1.5 3.0 0.5 0.0 1.2 0.8 5.3 20.4 1.4 10.8 7.7 4.7 25.3 7.2 18.8 21.8 0.0 6.6 1.3 2.8 6.4 0.2 30.1 50.9 5.3 7.9 1.8 0.0 2.4 3.3 5.9 7.9 5.4 31.5 0.0 3.0 3.0 6.6 0.7 27.6 13.1 16.2 0.0 4.1 3.7 11.7 6.1 9.8 3.8 11.8 1.8 21.0 0.0 2.0 14.4 4.2 44.6 0.0 19.4 2.0 5.4 3.6 30.6 1.9 4.5 12.7 4.3 PLD2 ENSG00000129219 "Phospholipase D2" O14939 17 4807096-4823434 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "monocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013397 Approved NA NA "HPA013397: AB_1855328" "unprognostic (1.87e-1)" "unprognostic (3.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (2.90e-2)" "unprognostic (3.85e-3)" "unprognostic (3.64e-1)" "unprognostic (6.15e-3)" "unprognostic (2.58e-3)" "unprognostic (1.25e-1)" "unprognostic (8.10e-3)" "unprognostic (1.08e-1)" "unprognostic (2.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.85e-1)" "unprognostic (5.48e-2)" 9.9 6.4 9.0 8.2 10.4 2.0 11.0 14.6 10.8 14.9 7.6 18.1 13.4 6.1 11.2 11.7 36.2 13.0 12.3 7.2 10.5 7.8 7.2 6.9 11.7 7.5 10.0 7.0 14.9 12.6 11.4 6.5 14.6 12.2 11.0 8.1 9.8 13.7 26.7 4.3 27.8 6.1 11.8 8.9 7.8 7.0 3.5 13.2 7.3 7.3 20.0 16.8 10.6 20.6 2.6 5.3 4.1 7.4 1.1 3.1 2.9 7.5 12.0 10.8 11.3 9.3 12.5 12.2 5.0 10.4 8.7 7.0 12.7 9.0 3.3 5.8 12.7 3.2 17.5 8.3 10.9 8.1 4.2 4.1 1.1 8.9 7.8 6.8 0.0 8.3 18.3 16.6 7.8 7.1 12.4 20.0 2.3 1.2 3.1 6.7 5.7 0.4 1.4 5.6 6.3 5.2 3.6 6.8 0.8 7.9 12.9 3.5 6.3 9.2 10.9 6.8 9.5 7.8 1.8 15.6 5.7 5.8 12.8 7.6 2.9 1.3 0.7 8.8 1.5 3.3 4.1 6.9 1.6 2.0 7.4 1.5 2.6 2.0 1.5 5.3 1.5 0.6 0.7 0.5 1.1 7.2 2.3 3.1 2.9 9.0 10.4 14.6 10.8 10.5 7.8 10.0 7.0 12.2 13.2 0.0 0.6 1.4 8.3 11.2 1.4 1.2 7.6 5.3 4.5 1.8 0.0 18.5 1.7 8.3 0.0 8.8 4.7 0.0 10.0 12.3 6.0 9.6 5.7 2.4 11.9 0.0 1.2 8.6 5.7 0.0 8.9 9.9 6.8 29.7 5.9 7.1 7.9 7.0 8.1 3.1 1.7 0.0 4.1 0.0 2.9 10.7 14.5 2.9 4.6 10.0 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Hofbauer cells: 638.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "basophil: 149.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 149.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 490000 "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 45.7 57.5 44.6 23.1 79.0 12.8 21.9 35.5 126.1 31.2 23.5 25.4 17.1 22.6 26.3 35.0 18.3 30.0 30.8 33.0 46.4 73.4 22.1 25.6 49.7 25.2 44.7 53.9 44.8 42.5 32.9 122.1 38.9 62.2 29.6 16.1 31.6 35.3 37.2 27.4 24.2 23.5 25.6 28.6 48.9 23.0 17.0 19.3 11.9 20.6 11.2 12.9 27.3 20.7 3.6 23.0 149.2 24.6 9.7 7.8 16.8 14.1 43.7 28.3 44.5 78.9 37.6 21.6 35.1 35.8 25.5 29.2 8.3 16.0 6.1 36.9 30.5 8.3 6.6 6.8 13.8 11.2 22.9 24.9 6.6 15.0 10.4 53.9 2.7 75.9 71.5 28.9 19.4 13.4 42.8 21.4 10.1 23.3 24.9 18.3 18.5 4.8 13.1 18.5 23.2 9.0 6.1 21.6 25.2 13.1 10.6 20.3 33.8 16.8 10.4 18.8 30.9 14.3 47.6 37.6 21.5 10.3 18.2 7.8 26.0 27.7 6.3 34.6 11.0 13.3 149.2 24.6 35.3 7.8 12.8 6.4 3.6 6.2 6.9 23.0 3.1 6.5 6.5 2.5 9.7 5.7 3.3 6.1 16.8 44.6 79.0 35.5 126.1 46.4 73.4 44.7 53.9 62.2 19.3 29.8 62.9 34.4 70.6 31.5 98.5 18.5 25.5 12.0 28.4 54.1 31.4 137.8 18.3 50.7 5.8 46.8 52.7 0.0 51.3 94.8 142.4 49.1 59.9 35.8 638.2 114.4 69.9 90.9 219.8 8.6 140.4 84.2 87.7 44.1 36.8 99.5 49.7 41.2 135.1 30.0 39.3 19.4 53.1 13.9 57.5 29.2 163.8 35.4 34.5 52.0 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924816-104937790 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "blood: 229.9" "Group enriched" "Detected in some" 4 "B-cells: 25.7;Hofbauer cells: 28.1;Macrophages: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "plasmacytoid DC: 229.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 229.9" "Group enriched" "Detected in some" 5 "HMC-1: 34.9;RPMI-8226: 25.0;THP-1: 63.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2000000 "HPA051512: AB_2681515" "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.7 1.6 8.9 6.7 8.8 15.0 1.9 5.7 10.0 1.5 1.3 23.1 0.1 5.6 1.5 0.5 1.1 2.8 3.5 0.8 8.7 8.4 1.2 0.9 2.6 14.4 14.5 3.4 0.9 1.6 1.0 2.8 1.2 9.0 2.1 0.8 1.5 4.6 2.3 0.5 0.9 5.5 0.9 19.0 11.6 3.5 0.8 9.2 2.7 1.0 0.0 11.2 3.9 0.9 14.7 229.9 43.4 17.7 1.7 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 34.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.0 0.0 0.0 0.0 8.8 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 2.8 43.4 0.0 11.9 0.1 14.7 0.0 0.0 35.1 12.3 0.1 0.0 0.6 1.7 17.7 229.9 0.0 4.4 8.9 8.8 5.7 9.6 8.7 8.4 14.5 3.4 9.0 9.2 0.0 0.0 25.7 0.1 0.3 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.4 0.1 3.5 0.0 28.1 1.6 0.0 0.0 1.3 2.5 0.0 25.2 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.5 0.4 0.7 0.1 0.4 0.2 0.0 0.0 0.0 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160753315 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 269.9" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1391.0" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 1.2;HL-60: 3.6;RH-30: 4.0;U-698: 2.0;U-937: 1.6" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 41000000000 "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 269.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.5 0.0 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.2 0.9 0.0 0.0 0.4 4.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 1.0 0.0 2.0 0.0 1.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.6 28.1 2.7 0.0 1.8 0.0 0.0 16.6 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.0 0.0 1.1 1391.0 0.1 0.0 0.0 26.4 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 203.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.9 0.0 0.0 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55535050 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 9 "Ito cells: 254.8;Leydig cells: 203.1" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 93.3;fHDF/TERT166: 28.4;HMC-1: 48.9;HSkMC: 35.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 56.3 26.7 12.5 14.8 14.6 0.6 57.9 10.6 18.5 34.5 30.9 26.1 18.0 17.3 36.8 26.0 18.4 20.4 61.0 33.7 13.4 10.8 34.5 42.0 15.9 17.3 20.8 10.1 16.5 17.6 16.9 10.1 22.4 21.4 82.0 24.7 29.8 9.8 24.0 18.4 16.6 25.4 39.6 28.2 10.2 21.7 18.1 14.5 4.4 32.7 9.6 10.0 43.1 18.1 5.4 13.6 3.3 0.7 2.7 9.5 1.6 2.0 4.9 1.4 2.9 93.3 10.9 2.0 4.4 12.4 2.4 5.8 3.4 3.6 2.0 4.2 28.4 6.7 1.3 5.1 2.5 2.8 1.3 4.0 0.2 2.1 4.2 14.7 0.5 48.9 35.8 5.3 3.6 2.2 4.9 4.0 1.9 0.0 5.7 4.9 1.2 1.3 1.0 3.3 0.2 4.0 0.4 2.4 0.1 9.3 15.9 1.8 1.2 4.4 0.9 2.6 6.4 3.2 0.3 4.9 0.8 1.5 3.7 3.1 3.5 1.4 2.4 3.3 0.2 4.0 0.0 0.4 3.3 1.5 0.4 1.6 5.4 5.2 3.2 1.9 3.4 9.5 7.5 0.3 2.7 0.7 13.6 2.2 1.6 12.5 14.6 10.6 18.5 13.4 10.8 20.8 10.1 21.4 14.5 6.0 10.3 3.9 48.9 0.0 5.2 0.0 15.3 4.0 10.3 27.9 2.0 2.2 5.0 22.3 30.3 45.0 26.9 0.0 24.7 9.6 32.8 109.6 25.6 50.5 11.0 1.6 1.2 254.8 14.9 19.1 203.1 3.6 0.0 7.2 23.2 14.3 28.1 29.4 83.1 24.5 4.8 58.2 0.0 47.0 18.1 0.0 4.1 4.3 14.9 41.0 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291504 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Cholangiocytes: 188.5;Ciliated cells: 167.3;Ductal cells: 295.2;Rod photoreceptor cells: 190.0;Urothelial cells: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 4.4;MAIT T-cell: 9.4" "Lineage enriched" "Detected in single" 52 "T-cells: 9.4" "Cell line enhanced" "Detected in many" "A549: 34.1;CAPAN-2: 37.1;OE19: 63.6" "Low region specificity" "Detected in many" HPA055540 Uncertain Approved Mitochondria NA NA Mitochondria "HPA055540: AB_2682839" "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 1.4 4.7 8.3 5.3 20.9 0.2 17.5 2.0 11.1 30.4 18.2 28.1 13.4 27.5 7.7 4.1 9.1 38.1 31.2 1.5 13.6 7.1 4.7 1.1 3.7 0.8 37.1 6.5 2.4 19.8 0.6 4.1 1.8 16.6 10.7 15.3 6.7 45.8 19.0 0.3 19.0 21.9 3.3 26.0 1.4 22.2 2.2 25.8 0.7 2.2 5.9 5.0 12.1 5.7 0.0 0.1 0.1 0.0 0.0 9.4 0.3 20.0 34.1 0.5 0.0 0.0 0.1 0.0 2.0 0.0 6.3 4.9 9.8 37.1 0.0 21.9 2.9 0.0 11.1 0.0 4.4 2.9 0.2 0.6 0.0 13.7 0.0 7.6 0.0 1.3 1.3 1.9 3.2 4.3 13.9 1.0 0.0 0.1 0.0 0.0 22.8 0.1 0.0 15.2 63.6 0.0 0.0 0.0 0.5 16.0 3.2 4.3 10.2 5.6 9.4 14.7 1.5 12.3 0.6 1.1 13.9 9.2 0.1 14.8 0.1 23.3 16.5 3.9 0.0 11.4 0.0 0.0 0.0 4.4 0.0 9.4 0.0 2.0 2.2 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 8.3 20.9 2.0 11.1 13.6 7.1 37.1 6.5 16.6 25.8 6.0 6.9 0.0 113.1 0.0 17.7 0.0 188.5 167.3 64.8 21.0 9.8 0.2 3.3 295.2 0.2 3.3 108.1 0.0 125.6 5.1 0.0 71.8 1.1 0.4 0.9 15.9 8.2 0.0 1.3 1.4 0.0 1.3 0.0 4.6 39.9 12.1 100.4 109.1 0.0 1.0 190.0 0.0 0.0 0.3 28.1 0.0 0.7 0.0 113.0 167.4 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494747-56645301 "Enzymes, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Ito cells: 854.4;Leydig cells: 1011.7;Peritubular cells: 374.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 5.4;naive B-cell: 4.5" "Lineage enriched" "Detected in single" 7 "B-cells: 5.4" "Cell line enhanced" "Detected in many" "ASC diff: 105.3;ASC TERT1: 52.6;HSkMC: 65.0;U-2197: 95.5" "HPA028892, HPA072751" Uncertain Supported "Golgi apparatus" NA Yes "Golgi apparatus" "HPA028892: AB_10602149, HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 46.4 17.2 29.0 10.8 30.7 4.2 39.1 13.5 27.5 102.7 15.5 33.8 22.1 8.1 32.7 36.9 20.8 36.7 24.0 23.3 39.9 13.5 30.2 57.7 24.3 6.7 19.2 30.1 27.9 12.2 30.7 7.2 70.9 20.0 37.7 14.4 34.7 22.4 58.7 16.6 24.4 12.5 32.9 16.5 7.9 18.7 23.4 29.7 5.2 107.1 19.4 6.7 35.8 44.0 5.4 0.0 0.8 0.3 0.0 0.0 0.2 0.4 1.5 2.0 0.2 105.3 52.6 5.0 5.5 5.6 5.1 2.5 4.4 0.8 0.7 0.6 8.3 5.7 0.8 0.3 0.1 1.0 0.0 1.3 0.1 0.6 6.1 2.5 0.0 0.0 65.0 0.4 4.9 4.1 3.6 4.8 0.0 0.4 0.0 5.5 0.4 0.0 0.0 6.2 1.2 6.1 0.0 0.0 0.2 0.8 4.6 0.0 4.1 1.7 2.3 0.5 6.4 0.7 0.0 3.0 25.8 2.1 95.5 0.2 0.0 0.0 0.0 4.5 0.2 1.8 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.2 29.0 30.7 13.5 27.5 39.9 13.5 19.2 30.1 20.0 29.7 23.8 20.5 11.5 20.0 0.0 3.2 0.0 56.0 8.1 23.9 21.0 0.0 102.0 18.3 16.0 5.7 50.7 10.7 23.3 7.9 10.3 54.5 13.7 3.5 84.4 36.2 0.0 2.4 854.4 45.1 12.0 1011.7 10.2 0.0 1.0 10.3 146.0 8.7 7.0 374.8 18.2 2.5 135.8 0.0 4.3 2.5 0.0 179.8 4.3 7.8 16.5 PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120456954-120589855 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5;kidney: 12.6" "Cell type enhanced" "Detected in some" 11 "Cholangiocytes: 12.7;Distal tubular cells: 6.6;Early spermatids: 7.1;Late spermatids: 7.9;Leydig cells: 17.8;Peritubular cells: 7.4;Proximal tubular cells: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "eosinophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 62.8;U-251 MG: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" 0.6 1.7 11.4 1.2 13.6 4.9 3.1 11.6 18.2 3.4 1.2 12.1 1.0 0.7 1.7 2.7 0.9 1.2 11.3 0.7 15.9 17.4 12.6 2.8 0.5 0.6 15.5 6.0 0.6 0.6 0.4 0.5 0.6 26.5 3.0 0.8 0.0 2.0 6.1 0.4 1.7 0.8 1.5 19.1 0.5 1.2 11.1 12.5 0.0 1.5 0.0 0.5 0.8 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.8 1.7 1.0 0.0 1.0 0.0 0.0 8.0 6.3 0.1 0.7 0.1 0.9 1.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 62.8 6.5 0.0 0.7 1.6 0.7 0.0 0.0 0.0 0.7 0.0 2.0 0.0 0.0 0.0 3.3 0.0 0.6 0.1 0.5 0.0 0.5 3.5 1.4 0.0 9.0 7.2 4.0 0.3 34.8 0.0 0.0 0.0 6.6 0.0 1.9 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 13.6 11.6 10.0 15.9 17.4 15.5 6.0 26.5 12.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 12.7 0.0 0.0 3.5 0.0 0.0 6.6 0.0 7.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.0 2.5 0.0 7.9 17.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 7.4 7.6 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.3 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 77.8" "Cell type enhanced" "Detected in many" 4 "Glandular cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "memory B-cell: 37.2;naive B-cell: 65.4" "Lineage enriched" "Detected in all" 5 "B-cells: 65.4" "Cell line enhanced" "Detected in many" "RPMI-8226: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 5.5 9.3 6.9 11.9 7.9 4.8 8.8 7.5 6.7 11.2 11.5 3.9 33.9 14.4 5.7 30.9 6.6 10.2 21.0 4.6 6.1 6.1 9.6 20.3 7.5 12.0 4.5 5.1 8.4 77.8 4.2 29.9 8.3 6.7 27.9 12.8 16.2 52.0 36.5 2.3 4.7 18.4 5.2 3.5 12.8 16.1 4.6 4.4 3.8 11.9 5.0 14.8 8.0 6.7 65.4 5.3 13.3 3.6 4.3 5.0 3.7 5.5 11.1 6.6 13.5 13.0 12.7 9.1 15.8 19.9 8.1 10.6 5.1 8.5 0.4 13.5 16.3 11.7 6.2 5.4 11.5 6.9 3.5 3.5 9.8 4.7 14.8 22.1 2.8 11.8 9.9 12.0 11.2 14.8 14.3 13.1 13.1 0.4 25.5 9.8 11.4 6.3 4.7 10.0 22.5 3.8 6.9 4.9 51.3 20.2 7.2 5.2 8.0 6.5 10.1 9.2 6.1 21.6 5.5 7.8 5.7 5.0 9.6 4.1 15.8 10.4 1.6 15.8 7.5 9.8 13.3 2.7 4.5 3.0 2.7 5.0 37.2 3.9 3.8 2.5 65.4 2.0 1.9 1.6 4.3 3.6 5.3 3.4 3.7 6.9 7.9 7.5 6.7 6.1 6.1 4.5 5.1 6.7 4.4 8.9 44.0 74.7 61.1 0.0 5.3 0.0 38.2 101.7 39.8 71.5 15.7 39.2 36.5 59.1 22.7 13.5 17.2 0.0 78.1 37.8 35.3 138.3 29.1 20.7 32.8 58.8 43.3 16.5 9.1 6.2 16.4 24.8 0.0 10.0 73.6 37.6 56.5 36.8 8.9 20.3 3.5 12.9 0.0 24.7 4.3 0.0 73.7 17.0 51.4 46.1 PLPPR2 "LPPR2, PRG-4" ENSG00000105520 "Phospholipid phosphatase related 2" Q96GM1 19 11355386-11365698 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "neutrophil: 32.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 32.3" "Cell line enhanced" "Detected in many" "U-2197: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048973 Uncertain Uncertain Nucleoplasm NA NA Nucleoplasm "HPA048973: AB_2680580" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (7.10e-2)" "unprognostic (1.37e-1)" "unprognostic (9.60e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.82e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.46e-11)" "unprognostic (1.99e-2)" "unprognostic (1.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.17e-1)" 12.0 17.1 32.5 10.5 39.9 14.1 6.6 17.7 51.2 14.0 11.1 10.8 5.1 6.0 12.7 8.4 8.4 9.7 13.7 10.4 37.0 22.3 5.5 18.0 10.0 5.4 11.8 17.9 15.2 12.4 11.7 22.7 11.5 12.3 18.5 5.1 11.8 13.1 15.1 23.1 16.2 5.7 16.8 10.5 10.6 9.3 7.6 9.4 0.5 7.7 4.4 3.3 9.8 8.1 0.0 2.9 32.3 7.2 0.0 0.3 2.3 8.8 5.5 3.0 12.6 12.8 12.3 0.8 15.8 14.7 9.8 10.1 1.0 1.6 1.7 9.4 20.1 2.0 1.6 1.7 4.7 5.3 4.6 3.2 0.5 3.8 1.0 6.7 0.5 18.0 11.0 8.6 8.4 1.6 14.2 6.6 2.8 8.5 14.1 8.2 13.1 0.2 2.4 3.3 3.0 30.7 0.2 0.4 4.8 4.6 4.2 3.3 10.9 6.6 5.7 3.3 1.0 8.2 11.3 7.6 22.2 4.7 37.5 8.3 8.8 5.4 0.6 21.6 8.1 8.7 0.8 7.2 3.7 0.3 6.7 0.0 0.0 0.1 0.0 2.9 0.0 0.1 0.0 32.3 0.0 4.4 0.1 0.3 2.3 32.5 39.9 17.7 51.2 37.0 22.3 11.8 17.9 12.3 9.4 6.0 8.8 0.5 5.5 0.0 5.1 0.0 7.6 2.7 2.3 3.5 11.8 0.5 1.7 6.2 11.0 6.9 0.0 0.0 7.6 2.1 2.1 16.2 2.3 6.7 4.0 7.9 16.4 8.0 9.7 8.2 13.3 3.9 0.0 0.0 2.5 15.3 7.5 0.0 15.6 1.3 6.3 6.5 0.0 1.8 4.9 0.0 2.4 0.0 0.8 4.1 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821977 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 18.2;brain: 30.0;fallopian tube: 12.6" "Cell type enhanced" "Detected in single" 21 "Horizontal cells: 1.6" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "eosinophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.6" "Group enriched" "Detected in some" 6 "NB-4: 24.1;THP-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.7 0.7 20.5 1.2 30.0 18.2 2.1 0.1 21.3 0.9 0.7 0.7 0.0 0.7 1.3 0.7 0.7 12.6 1.1 0.7 14.4 13.1 0.7 0.7 2.6 0.9 3.9 14.9 1.0 0.7 0.7 0.1 0.8 4.7 0.9 0.7 0.1 0.7 0.8 0.9 0.8 1.0 0.7 1.1 0.9 0.9 3.0 3.1 0.0 0.7 0.0 0.7 0.8 0.0 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.1 0.6 5.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.1 0.9 0.0 0.0 0.0 2.1 0.0 0.6 0.0 0.2 1.7 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 0.4 0.0 24.1 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.4 0.1 0.0 0.0 2.7 2.2 51.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 3.9 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 30.0 0.1 21.3 14.4 13.1 3.9 14.9 4.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 PLPPR4 "KIAA0455, LPPR4, PHP1, PRG-1" ENSG00000117600 "Phospholipid phosphatase related 4" Q7Z2D5 1 99263953-99309590 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 55.3" "Group enriched" "Detected in some" 5 "Horizontal cells: 28.6;Muller glia cells: 25.5" "Cancer enhanced" "Detected in many" "glioma: 7.2" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 22 "non-classical monocyte: 2.1" "Lineage enriched" "Detected in single" 22 "monocytes: 2.1" "Cell line enhanced" "Detected in some" "BJ hTERT+: 20.3;BJ hTERT+ SV40 Large T+ RasG12V: 7.9;fHDF/TERT166: 6.8;SH-SY5Y: 15.3;U-138 MG: 7.6;U-87 MG: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (4.32e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-2)" "unprognostic (1.67e-2)" "unprognostic (2.95e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-2)" "unprognostic (9.09e-2)" "unprognostic (9.70e-3)" "unprognostic (3.36e-2)" "unprognostic (2.21e-1)" "unprognostic (7.25e-12)" "unprognostic (1.67e-5)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "unprognostic (1.16e-3)" 3.0 1.7 25.1 1.2 25.8 0.8 1.8 2.0 55.3 4.6 1.5 2.6 0.0 1.2 1.7 1.7 3.2 1.3 6.0 1.4 39.2 10.8 1.4 0.8 3.5 1.5 5.2 16.7 0.8 1.5 1.7 9.0 1.9 6.1 1.1 1.9 0.6 1.4 1.3 1.2 4.6 1.5 2.1 2.2 1.3 1.1 5.2 2.7 0.0 1.5 0.4 1.7 7.0 1.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.0 0.0 3.9 20.3 4.5 7.9 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 25.1 25.8 2.0 33.8 39.2 10.8 5.2 16.7 6.1 2.7 0.0 1.1 0.0 0.0 0.0 3.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.6 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 25.5 0.0 0.0 1.4 0.6 4.3 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 PMPCA "Alpha-MPP, INPP5E, KIAA0123" ENSG00000165688 "Peptidase, mitochondrial processing alpha subunit" Q10713 9 136410570-136423761 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA 6500 Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favorable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favorable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" 15.2 27.3 19.8 14.6 23.8 20.1 13.2 20.3 24.3 12.3 15.1 13.0 10.4 18.6 14.2 14.1 16.5 13.6 14.9 37.0 15.6 14.8 17.0 48.3 12.3 18.4 15.2 21.9 15.5 18.2 14.7 19.5 15.6 16.8 15.2 11.9 12.8 20.3 17.1 56.7 17.5 17.0 13.8 14.1 18.9 16.3 23.2 12.5 14.0 15.0 19.8 15.3 13.1 13.4 25.5 30.1 17.0 25.1 32.1 30.8 28.2 14.4 27.2 13.0 26.2 9.9 14.5 20.0 15.1 12.2 21.2 15.4 31.0 17.3 20.3 15.9 15.3 11.3 33.9 24.0 22.1 9.4 29.1 29.0 16.3 35.0 37.4 17.4 21.2 14.2 21.2 15.3 16.5 8.5 12.0 17.9 18.9 41.3 13.4 13.1 40.1 20.0 27.3 26.5 25.9 25.7 24.9 18.4 44.9 14.5 10.4 26.7 17.6 20.3 29.0 17.6 9.3 39.5 28.9 14.7 15.1 16.2 12.4 19.2 8.3 10.9 21.8 19.9 18.5 13.5 15.4 25.1 17.0 27.2 24.4 26.4 25.5 25.7 29.3 30.1 23.7 30.8 26.9 5.9 32.1 23.2 15.3 24.3 28.2 19.8 23.8 20.3 24.3 15.6 14.8 15.2 21.9 16.8 12.5 14.9 25.3 23.9 29.5 24.5 22.5 31.3 10.2 13.4 18.2 21.0 21.6 90.0 41.4 28.9 19.7 20.2 19.7 0.0 26.4 41.5 17.6 17.8 24.3 54.0 33.8 17.5 20.0 20.3 17.4 12.4 17.5 14.1 15.1 21.6 22.3 19.3 25.1 17.3 21.2 37.9 25.3 38.8 16.9 32.8 39.5 23.5 86.8 23.0 30.4 23.5 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing beta subunit" O75439 7 103297422-103329511 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 57000 Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 29.1 41.8 31.8 23.0 34.3 41.5 31.6 41.1 38.4 29.0 26.9 21.6 28.2 35.1 32.0 25.9 27.9 26.9 23.5 41.4 27.7 20.1 45.9 47.2 21.9 31.3 32.6 35.0 36.8 40.6 41.1 33.9 24.8 34.2 31.6 31.5 20.8 30.6 31.0 31.5 31.6 31.0 25.7 27.8 27.9 33.6 31.3 35.9 37.2 33.2 24.2 30.0 30.7 27.9 19.5 18.4 9.7 16.1 12.9 21.9 15.7 12.4 18.0 21.2 28.6 12.9 26.2 16.0 11.6 20.0 23.5 28.0 19.2 14.3 32.0 18.6 19.7 25.1 16.2 25.5 18.7 22.4 11.2 30.4 11.1 30.9 25.6 15.7 15.2 13.1 23.9 17.4 18.3 17.7 22.5 12.4 24.1 21.4 32.6 21.4 28.9 25.1 35.8 26.0 24.8 22.6 17.6 14.9 32.5 22.0 22.3 26.7 32.6 15.6 46.2 22.8 22.4 18.9 20.4 10.2 20.7 24.9 36.9 21.5 25.0 31.9 24.6 15.4 24.5 16.3 9.7 14.1 9.3 14.7 16.1 16.1 19.5 17.1 14.7 18.4 14.3 21.5 17.4 4.4 12.9 13.6 9.4 21.9 15.7 31.8 34.3 41.1 38.4 27.7 20.1 32.6 35.0 34.2 35.9 29.8 31.7 53.2 52.9 32.5 29.3 64.2 28.1 49.5 40.9 26.2 21.6 104.2 61.3 64.5 72.7 34.3 36.7 0.0 64.0 49.3 41.1 31.6 58.9 46.5 48.7 22.3 26.0 24.5 42.2 18.6 48.1 38.4 25.3 93.8 43.0 33.6 54.8 42.1 46.7 96.5 33.4 64.7 42.9 84.6 53.0 32.9 104.5 57.5 55.1 47.7 PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA006782: AB_1855496" "prognostic favorable (9.18e-4)" "unprognostic (1.87e-1)" "unprognostic (4.31e-2)" "unprognostic (4.23e-1)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.24e-2)" "unprognostic (3.68e-3)" 13.1 32.4 11.2 22.0 11.8 24.3 15.0 18.0 13.8 14.0 17.4 17.0 26.4 15.6 16.7 25.3 13.6 18.1 18.2 16.8 12.3 9.5 20.1 16.8 15.9 21.0 13.9 14.2 17.1 22.5 19.7 26.8 17.1 12.9 18.7 15.0 19.6 20.3 22.4 12.8 15.3 15.7 13.2 10.1 30.7 17.9 17.2 13.9 22.3 23.0 17.0 20.6 14.6 12.4 7.9 7.5 19.3 12.7 2.7 7.7 3.8 13.0 8.8 8.9 14.0 8.5 6.6 14.5 21.1 10.8 9.8 8.6 7.0 17.2 8.5 6.7 6.4 5.7 10.7 3.2 11.9 5.8 10.9 13.5 14.4 16.6 6.1 6.4 13.6 19.3 6.2 6.3 8.9 5.8 8.7 12.8 10.7 7.0 17.1 12.7 8.3 13.7 10.8 8.3 13.5 18.0 11.7 8.2 17.1 10.0 27.9 10.6 17.1 9.2 27.8 4.7 8.1 4.8 8.4 18.1 19.1 11.7 4.6 17.4 18.9 7.6 6.9 17.3 6.1 15.2 1.4 8.8 12.2 7.7 8.5 6.4 6.5 6.6 5.8 7.5 7.9 4.9 4.4 19.3 2.7 12.7 4.3 6.8 3.8 11.2 11.8 18.0 13.8 12.3 9.5 13.9 14.2 12.9 13.9 14.9 23.4 40.2 28.5 11.8 40.7 8.9 15.3 24.1 9.1 19.2 76.6 37.9 19.9 36.3 12.0 20.2 24.9 0.0 34.6 29.2 14.8 28.4 27.8 18.7 34.1 31.8 29.3 31.9 22.4 20.0 55.0 24.9 13.5 42.3 23.1 20.6 38.1 20.1 42.1 26.9 76.0 19.4 14.4 18.2 29.6 11.4 41.2 42.4 27.4 25.2 PNLDC1 "dJ195P10.2, FLJ40240" ENSG00000146453 "PARN like, ribonuclease domain containing 1" Q8NA58 6 159800249-159820704 "Enzymes, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 26.7" "Cell type enhanced" "Detected in some" 11 "Cholangiocytes: 7.6;Early spermatids: 13.6;Late spermatids: 10.3;Spermatocytes: 11.1;Spermatogonia: 9.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basal ganglia: 5.7;cerebral cortex: 3.9" "Cell type enhanced" "Detected in some" "intermediate monocyte: 1.8;plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;HAP1: 2.3;hTCEpi: 3.8;RPMI-8226: 2.1;SuSa: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA052026 Uncertain NA NA "HPA052026: AB_2681699" "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" 0.6 0.5 0.6 0.5 5.7 0.4 1.4 0.2 3.9 0.3 0.3 0.3 0.0 0.2 0.3 1.3 0.2 3.6 0.3 0.2 0.7 0.2 0.8 0.8 0.5 0.4 0.4 0.7 0.8 2.3 0.3 0.3 0.3 0.3 0.4 0.3 0.0 1.2 0.4 0.5 1.4 0.3 0.3 0.4 0.5 0.3 26.7 0.3 0.5 0.4 0.3 0.7 0.2 0.0 0.1 1.7 0.0 1.8 0.4 1.0 0.4 0.0 0.4 0.2 1.8 1.0 0.0 1.1 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.2 0.3 0.1 0.1 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.0 3.8 0.0 0.1 0.2 0.0 1.0 0.1 0.8 0.2 0.1 0.8 0.1 0.9 0.3 0.8 0.1 0.0 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.9 0.0 0.1 0.2 0.3 0.0 0.3 0.7 0.1 0.0 0.6 0.1 0.0 0.2 0.0 0.1 1.8 0.0 0.0 0.2 0.0 0.7 0.1 1.0 0.1 0.0 0.4 0.0 1.7 0.5 0.4 0.6 5.7 0.2 3.9 0.7 0.2 0.4 0.7 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 2.4 13.6 0.0 0.0 0.0 0.8 0.0 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.0 0.0 10.3 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 11.1 9.0 0.0 0.0 0.0 0.0 0.1 PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1895 "pancreas: 3207.8" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 3478.1" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;HDLM-2: 2.8;U-2 OS: 4.6;U-251 MG: 1.1;U-266/84: 1.5" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" NA NA 13000000 "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3207.8 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 1.1 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.5 0.0 0.0 0.0 3478.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 25.2 0.0 0.0 826.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427867-116477957 "Enzymes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 8.5;breast: 15.9;esophagus: 12.0;skin 1: 15.5" "Cell type enhanced" "Detected in some" 13 "Basal keratinocytes: 1.0;Late spermatids: 1.6;Melanocytes: 1.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "hTCEpi: 86.9" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" NA NA "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 8.5 0.1 0.0 0.0 0.2 0.0 15.9 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.4 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 15.5 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.0 8.1 1.9 0.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818902-825573 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 158.1;breast: 155.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 158.1 7.2 1.6 9.4 1.8 11.2 155.2 2.7 2.3 4.1 35.9 1.5 3.8 5.6 4.5 7.8 8.6 4.3 7.2 12.6 1.7 1.1 15.6 7.4 11.3 4.5 1.6 1.6 4.9 11.8 2.5 4.2 11.6 1.8 5.2 1.5 1.9 8.1 8.1 25.0 6.1 23.1 3.0 2.1 4.9 8.2 4.0 1.5 1.5 11.3 4.8 5.1 13.0 18.6 4.2 6.5 18.7 8.5 3.6 5.3 3.6 10.5 8.3 1.7 4.5 65.2 5.8 11.2 11.3 9.1 7.1 6.3 7.1 10.7 6.3 6.7 8.5 4.4 9.5 2.6 4.7 2.2 8.1 23.1 8.7 3.7 11.3 21.4 6.0 11.0 11.4 6.1 4.7 5.5 7.3 5.8 4.7 7.4 6.4 6.3 6.2 8.0 13.1 5.0 10.8 17.9 7.7 3.8 14.1 7.0 2.4 6.4 8.5 21.0 17.9 6.5 1.1 7.7 6.9 10.4 6.4 5.0 4.1 5.1 24.7 15.2 5.3 16.1 8.5 4.4 9.3 8.5 18.7 3.6 5.5 3.5 4.2 4.6 5.2 5.7 3.6 5.3 4.3 7.7 3.6 6.0 6.5 3.9 3.6 1.6 1.8 2.7 1.9 1.7 1.1 1.6 1.6 1.8 1.5 6.0 16.9 27.0 63.2 39.3 8.8 42.3 63.7 5.3 13.6 48.8 7.9 56.2 28.2 55.9 14.2 38.0 114.0 23.3 57.3 27.0 25.2 72.1 11.5 41.9 27.6 11.1 49.4 84.1 28.5 4.2 44.8 24.9 40.5 27.9 80.0 34.7 98.9 112.2 36.7 37.9 7.5 64.7 32.2 42.2 28.2 36.0 141.7 36.2 41.4 167.2 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923739-43964488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease mutation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "liver: 31.1;retina: 39.3" "Group enriched" "Detected in some" 6 "Bipolar cells: 37.1;Cholangiocytes: 15.3;Cone photoreceptor cells: 17.7;Hepatocytes: 42.7;Rod photoreceptor cells: 34.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 13.5;LHCN-M2: 15.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.8 0.4 0.5 0.7 1.0 0.3 4.0 0.3 2.4 0.8 1.3 0.4 0.0 1.0 0.5 1.9 0.4 1.1 0.5 0.9 0.8 0.6 4.6 31.1 1.4 0.4 0.3 1.8 0.5 0.2 0.6 0.2 0.4 2.2 0.2 0.2 39.3 0.9 0.2 2.2 5.3 0.6 0.2 0.5 0.6 0.3 0.5 0.3 0.0 0.2 0.0 0.3 0.2 0.4 1.2 0.7 1.8 0.6 0.9 0.8 0.0 3.9 1.3 13.5 5.5 3.8 4.3 0.4 2.4 1.4 3.3 7.2 3.9 7.1 0.0 2.1 4.0 1.9 3.4 8.4 3.9 2.8 0.0 0.7 0.2 3.2 7.2 6.2 0.0 0.2 4.9 3.1 10.6 0.5 5.7 0.4 0.1 0.0 0.0 15.3 0.6 0.2 0.0 9.2 0.4 0.0 0.0 7.3 0.1 1.5 0.2 1.2 0.1 2.7 1.1 3.8 2.4 4.2 4.6 0.4 1.3 4.1 0.1 0.1 0.0 0.0 0.0 11.6 0.0 4.8 1.5 0.6 0.4 0.5 0.4 0.3 0.7 0.4 0.3 0.2 1.2 0.6 0.8 1.8 0.9 0.3 0.7 0.2 0.0 0.5 1.0 0.3 2.4 0.8 0.6 0.3 1.8 2.2 0.3 0.0 0.0 0.0 0.5 0.3 37.1 1.1 15.3 0.0 0.0 0.0 17.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.0 42.7 0.6 0.0 1.7 0.6 2.6 0.0 0.3 0.0 1.7 0.0 0.5 1.3 1.5 0.0 0.7 5.0 34.3 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.4 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Distal tubular cells: 81.2;Proximal tubular cells: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA003656 Approved "Intracellular and membrane" NA NA "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 11.3 18.1 12.6 6.0 18.8 4.7 13.9 5.0 11.5 8.9 8.9 8.5 13.3 11.2 9.2 11.4 13.2 15.0 6.2 24.0 10.9 11.9 26.5 39.8 5.8 6.3 12.0 8.7 14.0 21.0 13.3 17.0 4.7 12.2 8.0 7.5 13.1 18.9 10.7 40.9 10.8 10.5 7.4 11.2 5.4 11.5 7.8 10.6 7.2 23.6 21.1 8.9 6.6 9.5 13.2 18.3 7.6 10.4 9.0 10.3 8.4 18.4 7.6 1.2 19.0 0.4 0.2 5.1 5.7 0.6 10.0 6.2 7.6 6.8 5.8 0.0 1.8 0.1 10.9 0.0 19.3 17.1 0.2 13.5 4.1 14.7 15.9 12.7 7.2 6.1 13.0 19.8 5.1 11.9 2.4 6.9 0.2 16.2 0.2 0.1 4.8 0.1 7.2 20.1 12.8 16.1 0.1 0.1 6.4 13.2 8.4 11.0 5.5 17.4 7.2 9.8 22.6 11.2 5.4 3.9 0.1 5.0 15.3 0.1 8.8 0.1 11.0 0.1 0.0 1.6 5.2 9.8 7.6 5.4 10.4 6.2 12.3 7.8 5.9 18.3 13.2 10.3 9.8 0.7 9.0 9.7 13.5 4.8 8.4 12.6 18.8 5.0 11.5 10.9 11.9 12.0 8.7 12.2 10.6 8.9 12.2 10.2 12.9 10.5 11.3 43.9 22.9 26.8 9.1 19.2 0.0 24.2 81.2 29.5 2.3 11.6 26.5 0.0 42.6 18.0 10.3 13.5 8.1 58.6 26.3 9.5 19.0 13.5 7.2 2.2 15.3 11.0 16.9 17.2 30.1 29.0 29.8 28.1 19.1 97.0 12.8 6.5 11.3 15.9 21.3 14.6 11.7 5.2 34.5 13.7 PNPLA6 "iPLA2delta, NTE, SPG39, sws" ENSG00000032444 "Patatin like phospholipase domain containing 6" Q8IY17 19 7534004-7561764 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease mutation, Dwarfism, Hereditary spastic paraplegia, Hypogonadotropic hypogonadism, Mental retardation, Neurodegeneration, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007522, HPA064773" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Endoplasmic reticulum, Cytosol" "HPA007522: AB_1079649, HPA064773: " "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (3.23e-2)" "unprognostic (2.78e-1)" "prognostic favorable (5.25e-4)" "unprognostic (3.53e-3)" "unprognostic (1.50e-1)" "unprognostic (2.07e-2)" "unprognostic (1.62e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.36e-1)" "prognostic favorable (7.53e-4)" "unprognostic (3.10e-3)" "unprognostic (3.50e-1)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" 12.9 19.7 25.9 25.0 29.3 22.3 17.8 22.1 35.8 10.2 15.9 26.1 10.0 26.3 13.7 6.3 16.4 12.6 14.0 12.0 22.6 19.1 17.1 13.7 30.4 17.6 36.3 19.2 12.5 14.2 15.6 21.6 13.9 29.2 13.4 8.9 15.8 13.7 14.3 27.0 15.3 28.7 14.5 23.5 28.3 12.2 31.3 33.0 7.1 14.7 6.1 8.8 15.9 14.7 3.8 7.3 21.8 19.0 5.0 3.9 4.1 13.2 31.9 6.3 15.2 11.0 16.0 14.5 17.2 17.7 13.4 12.4 7.4 18.3 10.9 29.3 22.2 8.3 17.0 5.3 16.2 6.9 26.6 12.3 7.2 17.0 5.6 12.7 8.0 22.5 13.8 9.4 17.2 10.0 21.3 26.4 13.0 5.9 15.1 11.9 6.2 8.8 10.5 6.9 6.2 29.3 7.1 3.8 12.8 11.9 12.6 8.0 13.9 14.6 6.6 18.7 8.9 5.9 11.5 27.9 16.3 9.6 22.3 18.0 17.9 11.5 4.8 27.4 9.5 15.2 7.9 6.1 21.8 3.5 12.1 3.5 3.8 2.5 3.8 7.3 2.8 2.2 2.9 1.9 5.0 19.0 2.4 3.9 4.1 25.9 29.3 22.1 35.8 22.6 19.1 36.3 19.2 29.2 33.0 6.0 11.8 6.5 2.7 4.2 10.9 8.6 17.8 8.1 6.8 31.4 25.5 14.9 1.7 13.7 60.0 10.8 52.1 0.0 6.1 12.2 4.1 4.5 11.5 19.2 24.9 20.6 16.7 10.4 55.8 82.5 8.9 23.8 8.5 10.0 13.4 10.6 8.4 12.9 7.1 17.0 16.2 0.0 6.2 58.2 10.0 4.8 10.4 10.0 14.0 3.1 PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470422-108569666 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: AB_1851849" "unprognostic (4.48e-2)" "unprognostic (3.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (4.61e-1)" "unprognostic (2.73e-2)" "unprognostic (3.48e-2)" "unprognostic (3.32e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.86e-6)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (4.28e-3)" "unprognostic (1.24e-1)" 21.5 35.7 29.3 12.4 28.9 51.5 15.0 15.6 27.2 15.4 13.4 9.5 9.3 8.6 13.4 13.7 18.3 9.7 15.9 17.9 23.0 22.1 23.1 24.6 16.7 12.0 20.7 17.5 15.6 10.1 20.7 33.4 25.2 23.2 14.4 11.4 6.0 11.4 13.9 29.8 11.4 10.8 15.3 20.3 19.5 11.1 10.8 21.1 16.1 22.6 13.0 15.3 22.5 12.8 20.0 19.3 16.7 26.8 14.6 12.5 13.7 14.1 6.4 11.3 10.1 25.2 17.4 16.7 13.5 23.8 11.1 18.6 6.1 8.1 7.9 17.1 13.2 22.4 5.4 19.1 8.6 16.9 11.8 5.3 5.4 10.5 4.5 18.4 3.7 11.2 15.7 16.3 14.9 13.8 12.2 15.0 8.9 6.3 22.7 13.8 9.3 8.7 8.9 5.0 8.9 9.1 3.2 11.9 16.7 13.3 18.0 9.4 13.2 12.9 14.0 16.2 14.9 5.9 6.4 12.1 18.3 8.2 27.2 7.4 19.3 19.5 11.7 17.4 5.7 11.8 14.1 19.7 16.7 10.5 21.8 12.5 20.0 10.3 10.3 19.3 18.7 11.2 10.7 16.5 14.6 26.8 7.6 12.5 13.7 29.3 28.9 15.6 27.2 23.0 22.1 20.7 17.5 23.2 21.1 38.7 43.0 28.7 103.5 82.5 61.7 43.5 10.2 81.7 58.0 22.7 17.7 46.4 79.6 26.9 49.7 39.4 25.7 0.0 33.2 30.6 50.6 71.1 70.4 40.3 28.4 30.2 54.7 19.6 49.4 40.1 29.7 48.1 52.3 17.2 16.2 37.9 25.2 14.1 37.1 33.7 29.7 19.4 38.2 17.7 27.4 118.6 108.9 23.5 13.6 109.8 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324707 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "liver: 144.1" "Cell type enriched" "Detected in some" 47 "Hepatocytes: 399.2" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 1.5;HeLa: 1.0;RH-30: 1.0;U-266/70: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA001610 Approved "Secreted to blood" NA NA 96000000000 24000000000 "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 1.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 144.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 0.0 1.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.4 0.0 0.2 0.0 1.0 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.2 0.4 0.0 0.5 0.0 0.1 0.0 0.2 1.0 0.3 0.0 0.0 0.2 0.3 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.0 399.2 0.0 0.0 2.9 8.0 8.6 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404863-95435329 "Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 81.0" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "myeloid DC: 22.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 22.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" NA NA 350000000 "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" 17.0 42.2 54.1 7.5 59.1 3.3 23.1 25.4 52.2 16.5 24.0 29.7 7.4 28.2 16.6 22.7 10.2 15.0 18.9 13.1 57.2 31.4 23.9 81.0 33.1 4.5 41.4 31.0 10.6 7.2 10.9 15.0 34.3 34.8 14.7 31.1 9.9 8.5 17.2 4.3 19.4 19.1 18.4 44.2 7.3 8.8 9.6 40.1 1.8 13.6 5.1 11.2 13.7 8.1 0.9 22.1 0.5 5.2 5.0 3.5 3.0 9.6 60.7 49.4 26.7 6.9 15.3 13.9 19.8 23.2 15.4 16.8 13.7 22.2 0.0 27.8 19.5 29.6 6.5 9.0 15.2 17.6 0.1 11.8 4.9 36.5 45.2 11.0 0.0 6.8 22.1 17.6 8.3 11.3 31.6 31.9 0.0 3.2 0.2 45.4 8.8 0.0 5.4 9.7 25.9 14.1 0.0 23.3 2.3 47.7 7.6 3.4 10.6 28.2 31.5 19.0 29.8 9.3 3.2 34.7 23.2 16.9 7.8 19.0 5.2 6.0 0.0 21.7 4.5 30.2 0.0 5.2 0.5 3.5 2.6 3.1 0.9 1.3 3.2 22.1 0.4 1.9 2.4 0.0 5.0 1.2 5.3 0.6 3.0 54.1 59.1 25.4 34.3 57.2 31.4 41.4 31.0 34.8 40.1 119.1 85.8 10.2 37.2 14.9 3.9 25.4 71.4 37.5 67.1 80.3 0.0 66.3 8.3 132.9 1.4 51.7 71.3 70.0 44.3 257.9 23.1 23.4 13.9 127.1 35.6 36.5 12.1 36.8 21.8 2.0 15.0 30.4 106.3 20.8 37.6 174.2 71.8 87.7 20.5 39.6 7.9 19.4 40.1 1.9 5.5 14.1 42.1 9.2 65.6 18.4 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359944-95396368 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 148.0" "Cell type enriched" "Detected in many" 14 "Hepatocytes: 460.4" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 12 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 12 "NK-cells: 1.1" "Cell line enhanced" "Detected in some" "A549: 20.2;CACO-2: 6.5;CAPAN-2: 4.9;Hep G2: 22.4;T-47d: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 350000000 "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 0.4 0.7 0.3 0.1 0.6 0.0 6.9 0.2 0.5 0.9 1.0 0.3 2.3 1.5 0.2 1.2 0.2 0.4 0.7 0.4 0.7 0.3 0.7 148.0 4.0 0.0 0.4 0.2 2.4 7.1 0.0 15.5 0.2 0.5 0.2 0.4 0.8 21.4 5.5 0.1 1.8 1.7 0.1 0.3 0.2 0.5 3.6 0.4 0.4 1.5 0.0 1.1 0.5 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.2 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 12.6 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.5 0.7 0.3 0.4 0.2 0.5 0.4 6.0 32.1 1.4 0.7 0.8 0.0 0.3 25.5 8.1 14.8 3.5 0.0 1.5 1.7 0.2 9.0 0.5 4.0 0.0 1.8 1.9 2.6 2.2 0.0 460.4 0.2 0.0 0.0 8.6 7.0 3.6 7.5 0.0 13.5 0.0 2.3 3.0 1.5 0.0 2.8 5.2 0.0 0.0 0.1 17.7 13.6 1.1 1.1 0.5 2.3 0.3 POP1 ENSG00000104356 "POP1 homolog, ribonuclease P/MRP subunit" Q99575 8 98117297-98159834 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066194 Supported Nucleoli NA NA Nucleoli "HPA066194: AB_2732742" "prognostic unfavorable (2.54e-4)" "unprognostic (9.42e-2)" "unprognostic (5.96e-3)" "unprognostic (3.31e-2)" "unprognostic (1.46e-1)" "unprognostic (7.46e-2)" "prognostic unfavorable (1.26e-6)" "prognostic unfavorable (9.88e-4)" "unprognostic (4.85e-1)" "unprognostic (1.47e-1)" "unprognostic (3.79e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (2.96e-1)" 6.1 5.5 7.8 9.0 9.7 3.7 5.8 14.3 10.2 4.3 5.4 5.2 2.7 4.3 6.0 4.2 9.1 6.6 3.9 5.0 5.7 4.7 10.5 6.4 5.2 9.1 4.1 7.6 8.4 5.8 7.6 11.1 3.5 7.4 5.0 13.8 6.2 5.1 4.2 5.7 8.2 5.1 5.2 4.0 8.8 5.7 11.8 6.2 8.8 5.0 5.6 11.3 4.3 5.0 10.5 7.7 10.9 7.4 4.1 9.8 2.5 12.7 7.7 8.4 7.7 2.9 2.1 5.6 10.9 9.2 11.4 8.5 7.9 8.3 9.0 15.8 7.9 5.5 8.5 24.2 10.8 12.3 6.5 10.2 17.8 6.1 5.3 1.3 9.4 11.3 1.8 2.0 12.6 5.0 3.5 8.9 4.3 9.7 8.1 10.7 10.1 13.6 4.8 6.3 14.9 10.6 11.3 4.9 6.5 8.3 6.8 20.0 4.7 5.0 8.6 3.8 5.0 11.6 3.5 12.0 10.0 7.2 12.6 21.6 8.1 7.6 19.3 7.9 10.2 8.8 10.9 6.7 4.6 9.8 7.4 7.8 6.2 7.1 6.5 6.2 10.5 9.3 8.6 0.9 4.1 3.4 7.7 5.9 2.5 7.8 9.7 14.3 10.2 5.7 4.7 4.1 7.6 7.4 6.2 3.0 3.8 5.1 4.8 3.3 7.8 2.8 0.0 2.7 4.5 5.2 0.0 3.2 5.0 9.5 9.8 2.9 1.3 0.0 5.0 2.8 2.7 3.5 1.1 5.5 3.0 1.6 0.0 3.1 1.6 1.8 4.9 3.2 0.0 9.0 1.6 3.1 6.4 0.0 4.2 7.8 9.6 6.5 2.7 3.9 15.7 2.0 2.5 1.9 2.7 3.9 POP4 RPP29 ENSG00000105171 "POP4 homolog, ribonuclease P/MRP subunit" O95707 19 29604017-29617237 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042748 Approved NA NA "HPA042748: AB_10964774" "unprognostic (5.88e-2)" "unprognostic (2.78e-2)" "unprognostic (7.21e-2)" "unprognostic (4.00e-3)" "unprognostic (4.50e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (3.31e-4)" "unprognostic (8.35e-2)" "unprognostic (2.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.20e-2)" "unprognostic (9.47e-2)" "unprognostic (5.84e-2)" "unprognostic (4.21e-1)" "unprognostic (1.77e-2)" "unprognostic (5.23e-3)" "unprognostic (8.08e-3)" 23.7 17.1 14.6 14.5 15.8 13.6 11.1 14.1 18.9 8.9 19.4 14.0 10.5 13.8 15.5 11.8 15.1 12.1 9.5 17.7 13.8 12.8 21.0 22.9 10.4 12.7 14.7 14.4 11.0 15.7 10.6 10.0 15.2 14.7 12.8 7.7 13.6 17.3 10.6 29.1 12.2 17.1 11.0 15.1 15.7 15.3 17.2 8.0 17.8 18.0 16.2 16.3 11.6 10.0 28.9 27.0 35.3 34.2 23.3 35.2 26.9 17.2 30.5 3.0 2.4 4.0 2.1 11.7 16.3 2.1 4.9 5.0 13.6 4.4 14.8 28.7 3.4 4.3 8.1 4.5 5.2 1.9 32.8 28.3 17.3 9.9 8.4 4.2 19.7 9.1 2.3 3.4 3.7 2.0 2.3 3.9 8.0 15.0 4.2 3.7 18.0 11.7 3.9 4.9 6.6 16.2 7.9 20.3 7.5 2.6 7.9 7.1 7.0 16.9 7.8 8.1 2.3 6.9 5.7 11.6 6.2 18.7 9.5 14.2 14.1 26.4 18.2 7.4 11.0 5.8 35.3 27.0 26.4 26.7 34.2 19.0 28.9 25.5 28.4 27.0 23.6 20.9 25.3 16.4 23.3 26.7 22.0 35.2 26.9 14.6 15.8 14.1 18.9 13.8 12.8 14.7 14.4 14.7 8.0 20.8 18.3 33.5 16.7 11.2 15.2 22.6 33.1 28.1 7.9 31.4 7.9 47.6 68.0 46.6 8.6 26.7 32.3 0.0 68.2 37.5 18.2 17.1 25.4 36.5 54.8 11.1 16.7 26.4 26.4 11.8 15.3 28.4 23.6 67.7 24.3 32.5 51.0 24.6 26.5 49.6 9.3 25.8 18.6 37.7 13.7 14.1 39.6 21.9 25.3 15.2 POP5 ENSG00000167272 "POP5 homolog, ribonuclease P/MRP subunit" Q969H6 12 120578764-120581398 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047598, HPA069204" Approved Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA047598: AB_2680096, HPA069204: " "unprognostic (1.50e-2)" "prognostic favorable (2.68e-5)" "unprognostic (1.55e-1)" "unprognostic (3.61e-3)" "unprognostic (3.81e-1)" "unprognostic (1.50e-1)" "unprognostic (4.80e-3)" "unprognostic (1.28e-1)" "unprognostic (7.34e-2)" "unprognostic (5.75e-2)" "unprognostic (4.13e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.85e-4)" "unprognostic (3.07e-1)" "unprognostic (6.21e-2)" "unprognostic (2.68e-1)" "unprognostic (5.68e-2)" 16.3 33.8 16.2 25.6 14.4 14.1 23.9 8.7 16.7 18.6 17.5 13.6 24.2 11.8 14.5 27.1 15.9 14.6 19.5 25.8 18.1 13.9 24.1 24.1 18.3 19.7 16.9 15.9 11.7 18.9 25.0 17.5 8.2 14.2 15.6 18.0 15.1 20.9 22.6 13.3 12.7 15.1 19.5 14.4 20.3 15.2 9.0 12.1 24.2 19.8 18.9 19.6 13.7 19.2 32.0 33.5 3.6 19.7 18.2 28.2 22.8 20.1 34.6 12.3 15.0 23.4 12.6 19.6 17.0 11.0 20.8 16.0 29.8 9.3 11.9 25.9 13.6 10.9 21.4 20.6 32.4 18.7 28.1 31.2 14.5 22.6 33.7 16.5 20.4 15.2 15.9 18.7 24.0 11.0 11.7 17.3 28.4 17.7 7.7 20.6 44.4 16.6 18.4 14.7 29.3 29.9 19.5 15.1 32.5 29.1 20.8 9.6 10.6 28.8 8.5 21.9 14.6 39.4 19.7 12.5 10.9 16.3 17.3 18.5 19.9 33.5 21.0 21.2 24.9 17.3 3.6 16.2 3.5 24.7 19.7 22.6 32.0 22.6 23.0 19.0 22.4 28.2 26.8 1.1 18.2 16.7 33.5 21.4 22.8 16.2 14.4 8.7 16.7 18.1 13.9 16.9 15.9 14.2 12.1 11.9 25.1 40.9 40.5 17.4 19.6 53.8 40.8 25.4 37.5 73.3 13.7 49.9 131.0 34.2 1.3 26.7 23.2 23.3 38.8 36.9 22.4 23.7 54.2 46.1 46.0 17.5 21.2 23.9 18.3 2.7 33.4 31.2 47.2 27.1 27.7 54.1 31.5 24.6 35.3 99.7 28.3 19.4 28.8 19.1 33.4 21.7 14.8 37.4 37.5 25.7 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706053-100707495 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 12.3 16.6 20.5 15.1 21.0 25.3 16.1 25.1 33.2 11.3 14.7 8.7 14.0 17.5 13.9 12.5 20.4 13.4 13.9 19.6 18.3 18.1 13.1 31.4 11.7 18.2 16.8 22.0 13.2 21.2 6.6 11.5 18.1 13.3 16.0 8.1 10.0 24.2 15.8 46.4 22.6 17.6 12.3 12.9 12.3 15.5 7.0 9.4 11.0 11.6 20.5 11.8 11.5 12.5 32.1 30.4 46.4 35.6 42.1 37.0 32.0 24.6 24.6 9.9 17.5 5.3 5.1 19.5 14.0 6.6 15.6 15.5 35.9 16.0 20.0 23.6 6.1 17.2 15.7 14.5 16.5 7.7 18.2 43.9 9.0 16.0 34.4 9.0 13.8 11.1 5.9 6.2 15.9 15.7 4.4 8.6 14.3 31.9 17.9 8.1 70.0 34.6 47.3 30.5 15.7 34.0 26.2 10.5 34.0 9.3 13.6 20.0 20.3 11.3 34.9 16.6 9.3 11.5 14.0 8.4 21.6 26.0 42.4 27.5 7.6 20.6 35.9 13.6 23.9 23.4 46.4 35.6 38.2 32.4 34.1 29.4 32.1 32.5 31.6 30.4 26.4 29.9 31.1 21.9 42.1 35.3 27.9 37.0 32.0 20.5 21.0 25.1 33.2 18.3 18.1 16.8 22.0 13.3 9.4 17.9 14.2 18.6 25.5 93.3 23.7 23.0 33.1 25.4 10.3 33.2 5.9 127.6 79.6 64.3 1.9 39.5 51.5 70.0 76.1 144.7 43.7 49.5 17.3 88.3 57.5 30.2 38.6 28.8 23.7 5.6 38.9 27.4 54.0 41.5 44.2 33.8 71.6 45.0 35.0 66.2 18.4 45.3 39.1 7.5 43.1 104.3 116.5 27.4 49.7 41.7 PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Pyrophosphatase (inorganic) 1" Q15181 10 70202830-70233911 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "monocytes: 942.2;Muller glia cells: 982.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles NA NA 110000 Vesicles "HPA019878: AB_1855601, HPA020096: AB_1855600" "unprognostic (1.50e-1)" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" "unprognostic (2.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "unprognostic (5.36e-2)" "unprognostic (2.37e-1)" "unprognostic (3.53e-2)" "unprognostic (2.74e-1)" 46.6 55.5 41.3 36.8 56.0 24.2 88.7 66.8 62.2 34.8 45.7 25.2 43.7 33.2 30.4 59.6 48.6 38.1 31.5 30.0 46.7 54.2 40.7 59.0 39.1 54.6 74.3 47.5 17.9 72.6 23.3 29.5 34.6 60.7 24.4 53.4 26.1 36.8 42.1 37.0 24.6 41.0 32.8 72.7 22.4 32.5 25.1 47.2 20.4 52.0 35.8 44.4 32.7 40.2 21.5 48.9 1.0 17.7 15.5 35.6 25.3 58.1 24.1 21.6 63.7 58.8 51.9 20.3 21.8 41.1 34.2 36.1 73.5 30.9 84.3 19.9 21.7 22.3 47.1 63.2 42.5 35.0 79.2 60.1 23.0 24.4 41.9 37.2 56.7 14.6 34.0 50.9 27.4 73.1 37.6 41.4 42.8 53.7 45.5 32.2 34.1 54.8 53.2 22.5 80.7 67.0 33.6 24.8 49.3 71.4 36.6 65.0 21.9 24.0 94.1 18.6 15.8 23.5 25.5 18.7 9.5 36.2 31.2 41.3 15.0 32.8 61.8 14.7 79.6 8.3 0.0 17.7 0.4 13.3 13.8 35.6 21.5 30.8 23.1 48.9 13.8 34.2 28.9 1.0 15.5 14.5 11.3 30.1 25.3 41.3 56.0 66.8 62.2 46.7 54.2 74.3 47.5 60.7 47.2 208.4 123.3 139.4 261.1 238.0 182.7 75.4 170.7 77.6 178.6 102.9 163.0 265.6 170.8 481.5 21.2 172.8 203.5 23.3 678.8 222.3 156.3 255.5 36.8 132.9 92.5 81.0 156.1 38.1 69.1 22.2 101.5 81.2 172.1 942.2 201.5 982.7 518.3 210.2 110.3 442.0 227.9 64.7 156.5 149.9 174.8 224.7 205.5 113.0 280.4 496.2 PPA2 FLJ20459 ENSG00000138777 "Pyrophosphatase (inorganic) 2" Q9H2U2 4 105369077-105474081 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 8300 Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 9.2 18.0 18.4 17.2 15.4 24.0 20.6 12.3 17.6 10.2 19.8 9.3 20.3 18.1 13.3 20.7 14.8 10.7 18.7 42.5 15.6 15.3 23.7 21.2 23.1 34.8 17.2 12.1 9.5 25.0 10.4 15.0 9.3 15.4 16.1 16.7 12.6 21.4 26.8 29.6 15.0 16.8 22.8 12.4 12.1 15.0 9.7 10.7 9.4 14.3 28.2 10.6 12.2 9.5 20.0 35.3 14.7 20.8 22.0 17.0 14.6 11.4 5.4 10.6 18.0 6.8 5.4 7.7 6.5 8.5 8.0 5.7 12.1 16.8 9.4 8.6 5.2 6.4 5.7 21.2 10.3 9.4 13.3 7.6 8.4 8.8 11.0 5.3 19.9 8.2 5.2 10.6 5.5 4.3 9.1 7.6 16.5 14.0 13.0 7.2 14.5 17.0 14.4 7.7 22.3 18.5 15.1 6.5 9.3 26.3 8.8 11.0 6.5 4.4 26.6 9.4 6.5 13.9 16.3 4.0 5.7 11.2 6.2 11.2 11.5 14.5 9.8 10.1 10.8 7.7 14.7 15.0 9.7 15.3 20.8 13.3 20.0 16.0 16.2 35.3 16.6 15.5 17.0 6.4 22.0 16.2 17.7 15.9 14.6 18.4 15.4 12.3 17.6 15.6 15.3 17.2 12.1 15.4 10.7 8.9 50.5 30.0 71.8 44.4 30.3 55.7 53.5 57.6 43.3 31.4 15.7 106.7 223.8 100.3 91.0 35.1 73.1 23.3 104.8 78.8 31.9 70.3 43.9 59.7 73.9 20.6 63.1 23.4 36.7 95.8 25.6 65.5 72.6 46.9 86.9 28.4 66.2 97.6 30.4 222.1 16.9 38.8 49.5 16.1 9.4 50.4 70.8 45.8 109.9 75.5 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;testis: 20.2" "Group enriched" "Detected in some" 11 "Early spermatids: 51.1;Late spermatids: 94.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 3.6;HAP1: 1.3;HeLa: 5.3;SH-SY5Y: 2.9;SK-MEL-30: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.5 3.1 0.2 6.4 1.4 3.9 0.2 10.6 0.2 0.2 0.1 0.0 0.1 0.3 0.9 0.2 0.2 0.3 0.3 1.9 1.0 0.3 0.1 0.4 0.3 1.7 6.9 0.2 0.2 0.1 0.7 1.0 0.2 0.5 0.1 0.0 0.3 0.6 0.1 0.7 0.1 0.2 10.5 0.3 0.1 20.2 0.0 0.1 0.4 0.0 0.3 0.4 0.1 0.2 1.3 0.0 0.9 0.0 0.0 0.2 0.0 3.6 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 1.2 0.0 5.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.1 6.4 0.2 10.6 1.9 1.0 1.7 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 51.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.4 0.0 0.0 0.0 94.3 0.6 0.0 3.3 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 PPEF2 PPP7CB ENSG00000156194 "Protein phosphatase with EF-hand domain 2" O14830 4 75859864-75902571 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "retina: 75.7" "Group enriched" "Detected in some" 22 "Cone photoreceptor cells: 157.1;Rod photoreceptor cells: 518.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (3.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (1.53e-1)" "unprognostic (9.02e-2)" "unprognostic (3.32e-4)" "unprognostic (2.74e-2)" "unprognostic (4.54e-8)" "unprognostic (2.89e-1)" "unprognostic (5.98e-2)" "unprognostic (5.16e-1)" "unprognostic (3.66e-3)" 0.1 0.0 0.0 0.2 0.4 0.2 0.3 3.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 75.7 0.0 0.0 0.3 0.4 0.1 0.1 0.1 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 3.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.3 0.0 0.0 0.0 0.0 157.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.2 518.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 362.9;Late spermatids: 423.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" NA NA 850000 Cytosol "Plasma membrane" "HPA029209: AB_2672951" "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 16.2 11.7 13.8 15.0 18.3 64.0 15.1 20.5 28.6 15.5 32.4 13.3 9.4 19.1 17.4 12.7 15.2 10.7 10.8 37.1 13.5 16.1 22.8 26.7 14.6 11.8 15.6 19.1 12.1 13.3 18.2 12.2 15.8 24.3 16.5 19.4 12.3 18.7 13.5 56.1 16.7 25.2 15.0 13.8 11.6 14.9 29.7 12.7 23.4 13.3 11.6 13.4 15.2 16.5 4.0 2.7 8.0 2.1 4.7 4.5 1.9 48.6 11.0 9.6 8.1 14.7 13.6 12.2 13.4 15.7 10.0 9.5 6.2 14.4 29.3 12.8 15.1 7.4 10.8 9.9 13.8 17.5 26.3 5.6 18.0 7.8 9.6 12.3 20.4 12.9 11.5 16.6 11.7 16.0 11.7 9.7 15.0 9.9 23.3 12.1 21.3 26.5 4.8 9.0 9.7 9.3 9.5 22.2 9.4 12.0 23.4 16.3 12.2 13.9 16.3 11.3 9.1 16.4 8.9 13.4 20.8 20.8 9.1 9.5 18.2 10.3 34.3 9.5 8.1 10.5 6.7 1.8 5.1 3.5 1.8 3.8 1.7 2.8 3.1 2.7 4.0 2.2 2.1 8.0 4.7 2.1 1.6 4.5 1.9 13.8 18.3 20.5 28.6 13.5 16.1 15.6 19.1 24.3 12.7 14.9 23.5 24.8 36.4 68.7 40.5 85.1 38.2 9.4 15.9 36.6 60.9 27.7 28.2 22.7 362.9 29.7 97.1 70.0 21.2 20.1 41.4 73.1 26.5 65.2 24.8 55.6 58.3 21.5 27.7 423.8 39.1 33.5 57.3 16.2 52.8 37.7 29.2 66.2 49.1 73.2 62.7 38.8 44.2 46.9 24.8 72.0 61.4 35.5 36.5 38.6 PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol NA NA "Nucleoli, Cytosol" "HPA016745: AB_1855622" "unprognostic (5.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.96e-3)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.25e-1)" "unprognostic (6.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-2)" 23.7 13.8 31.2 12.2 33.8 24.7 15.2 32.6 25.2 16.3 18.2 26.0 13.6 13.2 15.7 20.4 14.9 12.7 14.3 21.1 29.6 24.6 19.4 27.7 13.4 16.6 34.6 22.4 15.8 20.9 34.6 17.9 12.1 22.9 20.7 19.0 24.3 16.4 16.4 72.0 12.5 14.3 21.1 27.3 16.1 14.8 13.3 34.1 19.1 15.0 13.1 16.8 18.2 15.9 6.5 5.5 11.1 5.0 4.7 9.5 1.6 17.0 15.3 20.4 14.8 25.4 11.9 23.1 13.2 15.3 13.8 12.2 20.5 11.1 18.8 20.8 15.3 11.2 9.3 22.7 8.7 20.4 18.9 8.8 19.8 9.1 14.1 20.6 17.7 16.6 11.4 15.2 10.9 18.6 10.8 11.2 8.8 14.4 20.0 12.3 14.2 17.5 28.5 25.1 15.8 5.2 18.6 22.7 12.6 32.1 17.3 16.4 20.7 11.9 17.9 15.3 31.7 9.7 12.4 10.2 12.1 17.4 10.0 12.7 17.5 11.4 17.6 6.4 29.5 8.7 8.3 3.3 11.1 7.2 4.5 6.2 5.8 6.9 6.1 5.5 6.5 9.5 6.4 9.2 4.7 5.0 5.3 6.2 1.6 31.2 33.8 32.6 24.9 29.6 24.6 34.6 22.4 22.9 34.1 17.9 17.3 29.6 37.1 53.8 47.2 45.6 28.1 5.3 20.5 38.4 60.9 27.6 39.7 35.0 59.2 17.3 39.4 0.0 41.1 24.4 27.3 58.6 26.5 49.9 23.3 101.7 38.6 16.5 48.5 32.9 33.1 41.2 54.0 37.9 27.4 54.4 35.2 40.3 31.8 30.8 128.5 25.8 38.7 33.8 26.0 54.5 54.0 54.2 32.8 45.7 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA022277: AB_1858839, HPA061848: " "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favorable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 12.2 7.0 6.1 5.7 9.2 13.6 11.9 30.8 6.6 11.1 10.0 10.6 7.8 7.6 12.0 8.3 8.6 11.1 8.3 5.8 7.7 4.4 7.4 7.4 9.2 7.9 10.3 4.6 17.3 12.3 8.1 8.9 18.5 8.8 9.3 9.4 8.2 8.1 6.8 9.7 8.1 8.1 8.2 7.3 9.2 7.3 16.2 12.5 15.5 8.7 6.9 7.0 7.8 11.3 7.3 13.1 20.5 13.2 6.8 8.3 6.8 2.7 5.5 6.2 5.3 4.2 2.6 8.0 4.3 2.9 2.8 4.0 5.6 1.6 7.9 3.6 3.0 1.1 3.0 4.0 1.8 3.8 1.4 8.8 5.7 5.4 6.5 3.5 2.3 4.4 2.3 2.9 4.2 2.5 2.3 6.4 3.4 4.1 3.3 3.0 26.9 6.2 3.4 2.7 2.6 4.3 7.6 7.9 4.7 2.5 3.4 8.5 6.2 5.7 1.9 1.3 6.9 2.3 3.1 4.7 3.7 10.1 2.8 2.3 5.4 5.7 6.0 1.5 2.3 2.8 8.2 13.2 14.1 6.7 10.2 5.9 7.3 5.6 6.1 13.1 5.9 6.1 6.2 20.5 6.8 6.1 5.8 8.3 6.8 6.1 9.2 30.8 6.6 7.7 4.4 10.3 4.6 8.8 12.5 29.8 7.7 13.7 4.0 18.7 12.0 5.6 5.1 2.7 4.5 5.2 3.9 13.6 3.3 6.0 51.4 15.8 10.1 0.0 6.0 5.1 11.2 6.9 1.1 2.8 7.5 3.2 13.8 20.3 23.0 8.1 12.7 9.8 3.3 6.4 9.0 6.4 5.1 8.6 7.1 4.2 10.1 0.0 12.0 24.5 13.9 15.7 32.3 7.5 10.5 5.5 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755869-58985176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 10.7;brain: 36.5;testis: 13.1" "Cell type enhanced" "Detected in some" 19 "Bipolar cells: 16.0;Cone photoreceptor cells: 29.5;Early spermatids: 22.1;Horizontal cells: 73.1" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 2.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Cell line enhanced" "Detected in many" "AF22: 10.2;HAP1: 16.5;MOLT-4: 7.8;SCLC-21H: 7.6;SH-SY5Y: 15.8;THP-1: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Yes No Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.7 10.7 15.0 0.8 7.5 0.7 0.7 11.9 23.3 1.0 0.7 3.6 0.0 0.8 1.1 2.2 0.7 3.3 0.8 2.3 36.5 5.4 1.9 2.4 1.0 0.9 3.2 9.2 1.0 1.7 0.8 3.4 0.6 10.5 3.2 0.7 3.5 0.8 0.7 0.6 0.7 1.0 1.3 2.7 0.8 1.4 13.1 2.0 0.0 0.8 0.0 1.0 0.6 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.5 0.0 0.0 0.8 0.0 0.0 0.8 1.2 0.0 0.0 6.5 0.1 0.1 2.3 0.0 16.5 0.0 0.4 0.1 4.9 0.0 0.1 0.0 1.2 0.5 2.1 0.3 1.3 0.1 0.0 0.5 0.0 4.1 1.6 0.0 0.0 2.9 7.8 0.0 2.9 0.0 0.8 0.0 1.3 0.0 0.0 0.0 7.6 15.8 0.2 0.0 1.0 0.1 0.0 7.0 0.0 0.0 1.9 0.0 2.4 0.0 0.1 4.4 0.3 0.0 2.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 7.5 11.9 14.0 36.5 5.4 3.2 9.2 10.5 2.0 0.0 0.0 0.0 0.0 0.0 16.0 1.6 0.0 0.0 3.4 0.0 29.5 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.1 73.1 2.9 0.0 0.3 14.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.4 0.0 11.7 0.0 0.0 9.3 2.5 0.0 0.0 0.0 0.0 0.0 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919420-21952837 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Ito cells: 61.4;Kupffer cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.7" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.7;monocytes: 13.9" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 36.5;K-562: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 780000 Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 25.0 15.6 14.0 21.8 14.3 24.3 18.4 16.9 16.3 18.1 13.2 7.6 12.5 9.6 17.6 9.7 23.6 12.3 13.1 17.0 13.9 14.9 13.2 8.5 21.6 15.1 11.6 10.1 14.4 10.7 8.3 7.7 28.1 14.5 15.6 4.9 11.2 11.2 16.5 15.8 15.5 11.1 15.4 15.5 31.4 10.5 6.7 10.9 6.2 10.9 15.1 10.2 15.8 37.6 0.7 5.5 17.7 13.9 1.7 1.4 2.8 9.2 9.9 6.4 6.2 3.5 6.3 8.1 10.6 6.3 9.4 6.5 4.5 3.7 5.6 13.3 7.4 4.0 11.2 2.8 6.6 3.3 8.0 9.0 21.7 4.6 4.3 5.9 8.0 5.9 5.9 2.0 9.1 4.3 6.7 36.5 5.6 55.2 2.4 12.0 8.6 4.7 6.2 2.7 2.9 10.9 7.1 16.5 1.6 3.2 3.9 2.6 10.0 10.0 3.3 8.6 2.6 4.1 5.6 30.7 11.3 11.5 10.3 10.1 4.7 3.7 6.2 11.4 15.3 21.6 0.0 7.7 3.3 1.0 12.9 0.7 0.7 0.7 0.6 5.5 0.6 0.7 0.8 17.7 1.7 13.9 1.4 1.4 2.8 14.0 14.3 16.9 16.3 13.9 14.9 11.6 10.1 14.5 10.9 6.0 5.9 5.1 4.4 7.2 7.0 13.1 15.3 4.0 3.4 1.8 2.0 13.3 3.3 4.9 1.1 31.9 2.0 0.0 4.3 7.2 7.7 3.9 3.5 5.5 17.5 7.9 5.8 61.4 32.9 1.1 6.6 18.0 6.8 8.2 3.9 3.8 5.6 0.0 6.3 3.4 6.5 6.5 5.7 7.4 10.5 5.0 2.5 5.7 3.8 5.4 PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381194-27409687 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.3" "Cell type enhanced" "Detected in all" 17 "Early spermatids: 1236.5;Late spermatids: 2467.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "HPA035530: AB_10670021, HPA035531: AB_10610283" "unprognostic (7.50e-2)" "unprognostic (8.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (4.15e-2)" "prognostic unfavorable (3.14e-7)" "unprognostic (9.36e-3)" "unprognostic (7.73e-2)" "prognostic favorable (6.08e-5)" "unprognostic (3.74e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-3)" "unprognostic (1.06e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (7.83e-2)" 12.7 17.0 9.9 19.9 9.2 19.4 30.2 10.9 19.3 17.9 14.6 9.1 16.9 12.1 26.8 12.5 19.4 19.2 17.7 13.6 8.8 7.6 12.6 18.6 14.7 20.2 9.4 8.0 13.4 18.6 13.8 13.2 11.4 8.7 10.2 16.4 9.1 16.4 18.7 24.1 10.9 12.2 14.9 6.7 14.7 14.1 93.3 8.4 25.8 14.1 19.1 22.5 25.2 17.3 20.2 40.3 24.5 29.1 22.7 38.3 19.0 50.9 42.1 30.9 23.7 19.7 16.1 28.5 31.8 20.9 38.2 30.7 64.8 27.0 60.2 23.4 22.5 32.5 27.9 51.9 35.7 34.4 25.1 42.2 58.6 30.7 68.4 17.8 57.8 24.8 17.4 20.7 38.9 31.4 18.2 36.5 29.9 49.0 18.7 28.9 45.6 42.9 62.8 44.9 35.4 30.4 44.4 64.8 31.6 25.8 35.6 41.6 47.1 28.5 31.6 22.8 25.6 17.5 19.0 29.3 28.6 34.6 25.0 48.2 40.8 45.7 95.2 22.4 47.4 21.4 22.1 17.8 24.5 26.9 22.3 26.5 20.2 28.7 27.9 28.5 18.0 21.7 22.4 9.1 22.7 29.1 40.3 38.3 19.0 9.9 9.2 10.9 19.3 8.8 7.6 9.4 8.0 8.7 8.4 59.6 43.5 61.1 65.0 72.0 42.0 33.6 50.9 61.6 66.0 66.3 27.5 71.4 28.2 97.8 1236.5 66.3 54.6 23.3 120.2 139.9 42.7 66.0 58.8 37.8 76.1 46.1 77.4 35.6 49.4 2467.5 65.0 65.1 23.6 147.9 59.6 64.9 122.3 42.1 66.8 48.3 34.6 45.3 45.8 594.3 323.3 70.4 44.4 79.7 83.2 121.2 PPM1H "ARHCL1, FLJ13253, KIAA1157, NERPP-2C" ENSG00000111110 "Protein phosphatase, Mg2+/Mn2+ dependent 1H" Q9ULR3 12 62643982-62935037 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;parathyroid gland: 36.6" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 5.3" "Group enriched" "Detected in many" 11 "dendritic cells: 2.3;granulocytes: 5.3;monocytes: 1.7" "Cell line enhanced" "Detected in many" "CACO-2: 35.9;HMC-1: 29.0;SK-BR-3: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020694, HPA044244, HPA058777" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB020694: , HPA044244: AB_2678871, HPA058777: AB_2683816" "unprognostic (3.41e-2)" "unprognostic (1.94e-1)" "unprognostic (9.51e-2)" "unprognostic (8.61e-3)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (5.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" "unprognostic (5.53e-3)" "unprognostic (2.19e-1)" "prognostic favorable (2.72e-5)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" "unprognostic (8.04e-3)" "unprognostic (1.14e-1)" 2.6 2.1 10.6 1.6 12.4 3.1 5.7 37.1 16.3 8.5 2.8 14.0 12.4 3.6 6.9 7.7 1.1 7.5 9.1 2.2 13.0 12.2 11.7 3.9 3.2 1.5 14.3 9.0 9.4 4.9 36.6 13.3 7.1 8.5 15.0 3.6 7.7 10.2 11.6 1.5 1.2 2.1 2.2 8.9 1.3 6.2 1.4 15.0 0.5 3.8 0.1 2.1 3.4 1.2 0.0 2.3 5.3 1.7 0.2 0.0 0.3 0.5 5.6 1.0 0.0 0.2 0.0 12.2 1.3 1.3 0.8 0.2 35.9 2.6 0.0 1.2 0.6 0.8 0.7 3.9 0.1 0.5 0.1 1.9 6.7 1.0 8.1 0.0 2.0 29.0 0.0 0.1 0.0 0.3 0.8 0.1 1.2 1.7 0.0 0.6 4.1 0.6 0.9 7.3 1.8 2.7 0.9 2.5 10.0 8.3 12.7 3.2 0.0 2.2 16.4 5.3 4.1 8.9 1.2 0.1 0.2 0.7 0.1 0.4 1.5 9.2 1.8 0.1 0.0 0.5 5.3 1.7 3.0 0.0 1.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.2 0.2 1.4 0.0 0.0 0.3 10.6 12.4 37.1 16.3 13.0 12.2 14.3 9.0 8.5 15.0 6.0 6.6 0.0 0.1 0.1 7.9 1.4 15.3 5.3 1.2 15.7 25.5 18.6 3.3 4.1 8.8 1.4 0.1 0.0 5.5 1.3 1.1 4.6 13.9 4.9 5.4 11.1 8.6 12.3 3.0 8.0 0.9 0.7 3.3 1.8 2.2 6.0 4.6 2.5 1.4 5.7 10.6 0.0 0.0 0.0 0.1 0.1 5.7 0.0 2.4 0.4 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 30.9;skeletal muscle: 45.1;testis: 31.9" "Group enriched" "Detected in many" 8 "Early spermatids: 105.4;Late spermatids: 189.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 30.9" "Lineage enriched" "Detected in many" 17 "dendritic cells: 30.9" "Cell line enhanced" "Detected in many" "T-47d: 20.4" "Region enriched" "Detected in some" 8 "olfactory region: 33.6" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 0.8 2.3 6.4 0.9 4.8 0.8 1.9 7.8 6.8 0.9 0.7 2.1 1.6 0.7 1.4 14.8 3.0 2.4 1.3 5.4 4.3 4.8 1.2 0.7 0.7 2.4 3.7 4.4 1.3 3.8 2.4 1.1 0.8 3.9 1.4 0.7 1.5 2.3 2.3 45.1 13.3 0.6 1.3 1.6 1.3 0.7 31.9 0.7 1.4 1.6 5.3 1.9 1.6 1.5 0.4 30.9 0.0 1.7 0.0 0.0 0.3 2.7 0.1 1.6 1.7 0.8 1.6 1.2 0.3 0.8 0.3 1.0 1.2 0.8 0.4 0.5 0.8 0.9 5.1 1.1 4.8 0.4 0.0 2.8 0.8 0.2 0.2 1.0 0.0 0.2 1.8 3.2 0.9 4.9 1.1 2.2 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.7 1.5 2.4 0.1 0.2 0.0 2.9 0.1 0.8 0.2 0.6 4.6 1.4 2.4 20.4 0.0 1.2 0.3 3.0 0.0 0.2 0.1 0.0 0.0 2.5 0.6 2.7 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.0 0.0 3.2 0.4 0.0 0.0 0.0 0.0 1.7 30.9 0.0 0.3 6.4 4.8 7.8 6.8 4.3 4.8 3.7 4.4 3.9 0.7 0.0 0.3 0.0 3.5 1.9 3.1 4.8 0.0 0.0 1.2 1.8 9.8 0.9 8.3 2.0 105.4 2.2 0.5 0.0 3.7 1.1 1.3 3.3 0.0 0.0 0.6 0.0 0.0 0.6 0.8 189.5 2.8 1.8 0.0 1.0 0.7 19.0 1.6 3.2 2.5 0.6 8.4 6.5 2.7 2.3 11.5 2.5 0.5 0.0 0.6 2.3 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 59.1" "Cell type enhanced" "Detected in all" 12 "Cardiomyocytes: 417.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 27.5;Karpas-707: 24.0;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria No No Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 3.6 6.1 19.2 8.8 17.2 5.9 9.3 21.1 26.8 12.9 3.8 12.5 2.5 3.0 21.8 5.5 7.6 14.1 6.0 59.1 23.1 14.6 11.8 5.1 6.5 14.5 21.6 15.9 22.0 7.3 10.4 8.4 6.4 17.0 11.1 4.3 4.7 7.1 5.3 8.3 1.9 6.7 18.2 15.0 10.9 5.4 12.3 19.4 7.3 5.4 1.9 15.8 6.5 8.1 31.8 38.8 5.5 3.4 7.9 16.1 7.1 2.2 0.7 2.8 5.0 4.3 5.6 1.1 3.5 6.4 11.8 14.0 5.7 0.5 27.5 3.9 2.2 5.7 0.2 8.4 2.7 4.7 21.2 3.5 4.9 2.2 5.1 3.3 6.7 2.6 3.7 1.3 7.2 6.3 2.4 1.9 11.9 7.3 24.0 3.4 3.1 8.8 3.7 1.7 1.6 1.1 5.0 4.7 10.5 4.1 0.9 2.2 1.9 2.2 0.2 2.6 4.9 11.4 1.9 0.4 4.1 2.1 1.3 2.0 7.6 6.9 23.0 4.5 5.5 6.8 5.5 2.9 2.3 12.4 3.4 16.1 30.4 11.8 12.4 5.5 31.8 11.7 14.1 0.9 7.9 0.9 38.8 13.3 7.1 19.2 17.2 21.1 26.8 23.1 14.6 21.6 15.9 17.0 19.4 44.7 11.3 104.3 16.5 8.8 97.4 417.4 7.6 24.1 17.0 47.1 17.7 9.4 132.6 5.9 6.1 17.6 2.0 46.7 5.4 2.6 28.3 31.2 18.5 22.1 23.1 81.0 9.2 20.3 11.1 6.2 22.2 13.9 20.3 111.0 15.6 19.2 6.3 4.9 29.7 39.1 14.1 25.8 38.7 35.6 21.3 4.6 2.4 54.8 2.9 5.7 PPM1L PP2CE ENSG00000163590 "Protein phosphatase, Mg2+/Mn2+ dependent 1L" Q5SGD2 3 160755602-161078907 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Bipolar cells: 59.9;Cardiomyocytes: 33.6;Cone photoreceptor cells: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 7.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "HDLM-2: 35.6;U-266/70: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019891, HPA019953" Approved Approved Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA019891: AB_1855631, HPA019953: AB_2170360" "prognostic unfavorable (4.90e-4)" "unprognostic (7.29e-3)" "unprognostic (2.01e-1)" "unprognostic (2.59e-2)" "unprognostic (8.03e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-2)" "unprognostic (2.49e-2)" "unprognostic (1.92e-1)" "unprognostic (4.51e-2)" "unprognostic (7.51e-2)" "unprognostic (2.69e-3)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (9.13e-3)" "unprognostic (2.07e-1)" 7.7 8.5 7.4 3.5 11.5 3.3 6.3 15.8 23.2 11.3 7.0 5.5 1.1 3.0 6.2 3.7 8.7 6.1 12.6 9.9 6.3 7.8 8.4 6.0 4.6 1.9 8.0 10.1 3.7 5.4 33.6 26.3 11.5 13.8 9.6 5.9 5.6 18.9 3.7 25.7 7.6 3.6 16.4 4.6 3.4 8.4 2.8 3.7 5.6 14.4 9.6 3.5 16.6 10.8 0.7 1.3 4.9 7.6 1.1 2.6 2.0 1.2 0.8 4.1 2.1 2.4 0.0 2.5 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.4 0.1 0.9 3.7 3.4 0.2 0.1 35.6 3.6 3.5 3.3 0.4 0.1 2.1 4.1 0.4 1.6 0.1 0.2 0.3 0.2 1.7 0.1 5.6 0.0 1.9 0.8 0.2 2.3 6.5 0.8 4.2 0.7 0.8 0.1 3.8 4.9 4.2 2.0 2.4 0.1 1.4 2.7 2.1 0.2 0.4 0.4 0.3 1.3 35.6 0.1 2.0 0.6 1.8 0.8 0.7 2.3 4.9 2.6 5.5 0.2 0.2 0.6 1.7 1.3 0.7 1.0 1.8 0.2 1.1 7.6 0.8 0.0 2.0 7.4 11.5 15.8 17.9 6.3 7.8 8.0 10.1 13.8 3.7 6.0 2.4 0.0 5.2 7.7 59.9 33.6 10.2 13.4 5.7 1.8 33.4 2.4 0.0 1.5 1.1 2.4 3.8 0.0 3.7 1.6 7.0 6.0 0.0 14.9 5.9 6.4 13.3 0.6 12.4 0.4 4.6 7.2 3.3 2.8 7.6 9.3 1.7 7.0 4.9 3.3 10.1 0.0 11.2 1.5 3.1 7.5 2.2 2.9 4.9 18.0 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245793-52250597 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 38.2;Kupffer cells: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 26.2" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" NA NA "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: AB_2684740" "unprognostic (4.26e-3)" "prognostic favorable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favorable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 14.3 7.2 13.9 22.7 14.8 16.5 26.3 3.6 9.2 16.9 12.5 4.6 7.8 4.4 13.6 12.0 10.8 11.7 19.4 14.5 8.7 8.5 8.7 4.9 30.1 38.0 5.4 12.3 14.9 5.9 6.9 7.5 8.6 4.9 15.1 6.7 11.0 10.8 12.4 3.1 7.5 8.8 18.1 6.8 22.5 8.3 6.2 5.9 20.5 11.3 9.9 20.5 11.3 13.5 5.0 9.6 19.6 18.6 7.4 15.0 10.1 0.4 2.5 1.5 3.7 22.8 22.8 2.4 5.8 12.5 8.2 6.4 1.4 2.0 4.2 1.7 15.1 4.6 0.7 5.1 1.1 3.3 5.0 1.2 9.6 6.7 1.5 16.7 1.4 9.1 18.8 2.5 9.2 5.8 13.3 10.6 19.5 1.6 7.0 9.6 1.0 6.2 0.4 2.0 1.9 7.0 1.4 0.7 9.2 3.5 1.1 1.1 4.5 4.2 1.0 5.2 3.4 3.6 3.7 7.3 3.1 5.3 1.8 0.7 26.2 4.8 4.5 6.2 2.5 3.8 1.2 15.7 8.5 15.0 12.4 11.7 5.0 11.8 13.8 9.6 3.8 11.1 13.8 19.6 7.4 18.6 5.8 13.2 10.1 13.9 14.8 3.6 9.2 8.7 8.5 5.4 12.3 4.9 5.9 0.0 4.8 11.5 3.9 4.5 1.0 2.0 5.1 1.4 3.4 1.8 0.0 3.0 3.3 1.7 9.9 6.9 0.7 0.0 1.0 5.3 8.2 2.7 5.7 2.4 38.2 1.6 1.2 10.4 40.0 14.2 11.8 24.5 5.0 10.0 0.2 5.1 1.6 1.9 9.2 2.2 0.4 19.4 6.1 0.4 3.6 3.3 1.6 22.0 0.7 1.8 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "blood: 43.7;skeletal muscle: 81.9" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 29.5;Extravillous trophoblasts: 60.2;Rod photoreceptor cells: 73.0" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "non-classical monocyte: 43.7" "Lineage enriched" "Detected in all" 10 "monocytes: 43.7" "Cell line enhanced" "Detected in many" "OE19: 16.9;RT4: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043577 Supported Vesicles NA NA Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 1.7 0.9 5.4 1.2 4.5 1.3 1.9 0.7 4.1 1.3 1.7 0.1 0.7 0.6 1.5 1.0 2.2 0.8 1.0 0.9 3.3 2.3 1.2 1.5 1.5 1.6 2.6 2.2 0.8 0.5 1.3 1.4 2.4 2.7 2.3 1.0 10.6 1.5 1.4 81.9 2.4 1.4 2.6 3.4 15.7 1.7 2.9 3.5 2.5 0.9 0.0 2.4 4.0 1.9 1.9 4.3 2.3 43.7 1.1 2.9 1.9 1.9 5.0 0.9 3.8 4.4 5.9 11.0 1.4 2.2 0.4 1.7 1.2 11.7 7.9 2.4 1.3 3.0 5.5 2.2 1.6 0.7 7.7 3.2 6.3 2.0 1.4 1.1 0.5 13.4 2.5 2.5 2.2 1.3 2.9 0.7 3.1 7.1 7.2 0.8 1.3 2.2 3.4 3.0 16.9 1.1 1.4 1.1 2.2 2.4 21.3 4.3 5.1 0.7 8.1 6.2 6.8 2.8 1.9 1.0 6.2 3.8 3.0 1.0 1.2 3.1 1.6 4.5 1.6 5.4 1.7 1.6 1.0 2.2 7.2 2.0 1.9 1.4 2.2 4.3 1.3 1.6 2.9 2.3 1.1 43.7 0.8 1.5 1.9 5.4 4.5 0.7 4.1 3.3 2.3 2.6 2.2 2.7 3.5 0.0 2.4 10.4 8.5 3.1 9.5 1.6 2.5 0.0 1.2 3.5 29.5 2.7 0.0 2.5 12.0 1.8 5.2 0.0 1.6 60.2 3.8 5.0 6.9 0.8 16.7 1.6 2.9 4.9 10.1 4.5 0.9 14.1 1.7 1.8 3.1 8.1 3.2 2.5 0.7 0.3 73.0 0.0 0.9 1.0 9.8 3.6 7.1 6.9 2.5 7.6 PPME1 PME-1 ENSG00000214517 "Protein phosphatase methylesterase 1" Q9Y570 11 74171099-74254703 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 69.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004541, HPA043900, HPA064396" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA 16000 Nucleoplasm "Nuclear bodies" "CAB004541: AB_628161, HPA043900: AB_2678722, HPA064396: AB_2685254" "unprognostic (2.99e-2)" "unprognostic (1.27e-2)" "unprognostic (2.28e-1)" "unprognostic (1.98e-1)" "unprognostic (9.26e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (4.45e-6)" "unprognostic (2.31e-2)" "unprognostic (7.92e-2)" "unprognostic (9.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.84e-1)" "unprognostic (1.54e-1)" "unprognostic (4.14e-3)" "unprognostic (1.33e-3)" 9.4 16.1 13.3 6.2 27.6 8.4 9.3 27.4 38.5 11.4 9.2 13.5 9.4 7.1 13.1 16.5 13.5 15.2 8.9 12.8 14.6 18.3 12.3 6.5 8.2 5.5 13.6 18.6 12.4 10.4 69.0 13.6 15.5 22.4 15.1 9.8 9.6 11.9 15.9 21.0 16.2 7.4 13.4 12.7 5.0 8.3 22.9 9.3 8.6 14.9 7.9 8.5 11.4 10.2 7.5 11.3 10.9 9.6 12.2 14.0 8.4 10.1 13.3 9.1 9.6 9.6 7.9 9.0 15.0 9.9 28.4 22.5 29.3 6.8 5.4 10.5 11.1 15.8 17.0 13.5 10.2 26.7 7.6 5.2 8.1 14.5 12.5 19.0 5.9 7.2 7.6 8.4 15.0 6.6 11.1 8.2 7.8 18.8 4.6 49.5 6.7 6.9 6.3 7.2 12.5 10.6 8.2 92.7 8.2 10.7 7.1 12.4 10.7 17.9 8.2 21.0 9.9 15.0 6.1 5.0 11.4 13.6 10.9 11.4 8.7 11.0 9.6 8.4 5.3 9.2 1.3 8.6 10.9 10.8 9.6 13.3 6.9 13.8 12.7 10.8 7.5 14.0 11.2 5.0 12.2 8.5 11.3 9.7 8.4 13.3 27.6 27.4 38.5 14.6 18.3 13.6 18.6 22.4 9.3 26.8 10.9 9.0 17.3 18.0 29.2 15.3 7.6 36.1 30.7 33.2 35.3 10.9 14.9 14.1 36.8 11.4 10.9 70.0 11.8 27.4 13.1 16.6 8.1 7.4 11.8 31.8 24.6 8.0 5.7 10.9 12.7 13.2 3.3 13.6 11.9 15.0 12.8 10.8 23.7 10.1 18.2 6.5 17.0 60.5 41.0 21.8 12.9 10.4 10.7 15.4 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398183-67421183 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 177.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 8100000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" 28.4 35.4 24.2 42.0 32.3 42.1 25.1 19.6 33.4 23.9 39.6 22.1 29.9 33.9 19.6 25.8 59.7 22.8 28.6 33.0 21.8 17.1 43.7 55.0 27.6 49.3 19.9 19.9 20.1 53.3 23.1 21.6 44.0 19.3 27.2 33.2 23.2 49.7 31.1 39.0 34.4 47.3 20.5 21.3 53.7 35.1 15.7 19.4 77.7 38.5 40.5 63.9 25.5 25.7 78.8 76.6 126.2 118.0 68.2 113.9 177.2 45.3 52.4 31.1 45.8 15.5 19.0 31.7 22.5 26.4 45.4 34.5 74.9 54.8 39.1 38.4 34.1 33.8 39.8 35.9 46.8 27.9 41.1 24.4 37.5 24.7 39.2 33.9 47.6 48.5 21.4 31.0 38.6 22.8 21.6 45.5 38.3 34.8 32.4 36.7 103.5 60.3 93.6 51.6 86.5 41.5 42.9 43.0 33.8 44.6 37.6 24.3 40.4 26.1 46.9 69.4 24.3 56.1 33.0 32.4 35.1 35.9 41.3 29.1 32.5 30.1 44.4 42.0 32.7 36.9 81.4 80.1 126.2 88.6 100.5 69.3 78.8 79.8 90.5 76.6 77.0 49.1 69.2 93.3 68.2 118.0 54.4 113.9 177.2 24.2 32.3 19.6 33.4 21.8 17.1 19.9 19.9 19.3 19.4 71.5 93.0 166.0 108.0 88.8 35.0 7.9 117.2 41.5 46.6 82.0 9.8 320.7 180.8 238.7 1.8 77.3 292.4 23.3 272.4 398.0 69.2 127.9 107.3 102.4 338.5 41.3 93.0 87.2 194.1 5.3 45.5 157.2 129.9 390.5 160.1 42.9 250.4 210.5 26.9 236.5 23.6 97.0 60.9 13.0 106.5 106.3 357.3 222.6 164.6 168.4 PPP1CB "PP-1B, PP1B, PP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7700000 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022558: , CAB069426: , HPA065425: AB_2685489" "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 28.5 22.6 30.0 20.5 37.6 29.5 32.4 19.1 29.8 51.1 39.3 21.1 30.7 24.4 58.0 31.8 86.0 37.0 33.3 67.1 27.8 27.9 32.0 20.0 35.3 22.3 27.4 24.4 39.7 21.9 48.9 28.7 42.3 22.0 46.4 27.7 25.2 36.5 38.6 99.6 25.1 30.0 100.8 27.5 25.2 31.4 25.5 21.4 28.1 27.5 32.9 25.3 82.1 50.5 15.6 25.4 41.5 42.7 23.5 28.3 17.9 37.1 23.4 81.7 25.2 28.0 26.1 47.6 20.0 22.8 19.5 19.3 20.7 22.0 29.7 25.1 20.6 21.6 23.0 23.2 26.7 23.2 47.1 12.0 22.5 28.8 22.4 61.0 25.4 10.6 20.0 38.0 21.0 44.0 20.5 23.5 15.8 20.4 29.5 25.5 18.6 26.9 22.0 26.8 28.6 18.6 26.4 72.4 22.6 63.3 44.9 22.4 27.7 31.0 34.6 27.1 24.4 16.7 14.2 28.1 26.1 28.7 18.6 24.0 21.1 33.1 60.9 27.7 27.4 19.3 22.5 24.8 32.1 16.8 37.8 21.3 15.6 25.5 19.6 25.4 13.4 22.7 25.5 41.5 23.5 42.7 19.6 28.3 17.9 30.0 37.6 19.1 29.8 27.8 27.9 27.4 24.4 22.0 21.4 86.4 80.7 105.5 134.5 437.2 53.8 298.4 104.4 129.8 72.8 294.8 25.5 104.9 207.2 242.7 375.6 106.2 128.9 163.5 183.3 167.5 182.4 291.0 146.3 81.8 104.3 154.1 271.6 108.6 144.9 304.1 182.1 233.4 318.9 92.8 133.9 100.9 238.2 181.4 283.9 113.6 53.2 620.9 265.8 57.5 61.8 400.4 328.6 110.8 99.3 394.6 PPP1CC "PP1C, PP1gamma" ENSG00000186298 "Protein phosphatase 1 catalytic subunit gamma" P36873 12 110719680-110742939 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 486.0;Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022645 Uncertain NA NA 7600000 "CAB022645: " "unprognostic (1.51e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.29e-2)" "unprognostic (7.26e-2)" "prognostic unfavorable (2.75e-6)" "unprognostic (6.55e-2)" "unprognostic (4.11e-2)" "unprognostic (6.91e-2)" "unprognostic (4.96e-3)" "unprognostic (5.72e-2)" "unprognostic (2.92e-3)" "unprognostic (1.66e-2)" "unprognostic (1.71e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" 23.3 29.4 27.4 23.4 29.8 28.8 24.1 31.9 32.3 25.2 63.3 22.2 15.4 63.0 25.9 19.8 31.3 22.9 21.5 66.5 29.4 21.0 19.8 20.6 19.6 41.4 32.0 21.9 31.7 38.8 19.6 25.8 17.0 25.9 26.1 36.4 28.7 26.9 19.4 63.4 24.0 73.3 46.3 25.9 27.1 25.2 43.7 28.3 42.3 25.9 18.3 41.3 37.9 23.2 17.8 19.1 30.8 19.1 8.5 14.9 12.5 45.8 27.7 47.4 34.6 28.8 39.8 36.3 26.5 39.5 44.1 35.3 47.3 23.4 71.8 20.1 28.4 27.6 26.2 63.5 34.8 61.7 41.7 42.8 46.4 20.8 48.2 23.5 59.0 40.4 25.1 28.5 33.3 29.8 46.9 50.9 40.8 46.2 19.5 40.3 19.1 47.7 66.2 74.6 30.3 41.0 47.0 32.7 45.4 28.2 34.9 38.3 30.8 29.2 35.2 51.0 43.6 55.1 46.2 22.6 22.5 37.3 30.3 33.2 30.7 31.9 61.5 21.2 43.0 34.2 18.7 19.1 30.8 8.2 14.9 8.0 17.8 14.9 11.7 19.1 15.4 12.4 10.2 16.3 8.5 18.8 7.4 13.7 12.5 27.4 29.8 31.9 32.3 29.4 21.0 32.0 21.9 25.9 28.3 32.8 25.1 131.3 108.1 185.8 159.6 121.9 61.1 12.0 21.6 34.9 64.8 118.3 79.6 59.1 486.0 77.6 126.9 70.0 109.1 164.3 97.7 101.2 58.7 34.2 118.8 96.9 81.6 50.3 154.1 696.0 83.1 84.6 121.4 49.5 90.9 76.2 74.1 147.3 130.4 66.8 93.8 109.9 130.8 168.8 41.4 183.6 110.5 92.7 142.6 110.4 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194334-134226142 "Enzymes, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved NA NA "CAB003848: AB_562203, HPA043236: AB_2678379" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 26.0 30.5 37.6 22.0 41.0 57.9 26.0 54.2 56.6 23.0 27.3 29.6 15.6 24.8 29.8 20.4 39.6 21.9 24.7 47.9 39.8 38.1 31.7 33.2 22.7 29.1 35.0 35.8 23.4 23.9 44.5 20.6 44.0 47.5 22.3 26.4 18.4 23.6 23.7 43.1 32.6 26.5 31.6 32.8 30.4 21.8 18.8 24.1 45.6 33.2 30.5 39.9 26.9 24.5 29.2 41.1 39.0 33.4 38.9 37.5 43.8 37.9 32.0 45.7 24.6 23.9 25.7 32.1 35.9 30.8 54.7 55.3 61.3 29.8 33.3 33.8 33.1 62.0 19.8 43.9 51.8 64.1 30.1 25.1 23.6 37.4 38.1 35.4 23.3 21.4 23.8 35.9 42.8 42.7 27.3 38.3 33.7 23.2 25.0 41.4 27.3 36.9 22.7 25.0 30.2 19.3 33.1 45.5 32.3 32.9 42.8 36.5 25.4 37.0 13.8 40.2 47.8 28.2 27.6 26.9 31.6 17.8 25.3 50.5 22.5 40.2 52.6 21.3 30.9 32.6 20.3 33.4 39.0 26.7 33.0 34.1 29.2 30.7 35.6 41.1 28.6 35.7 32.7 38.7 38.9 33.3 22.0 37.5 43.8 37.6 41.0 54.2 56.6 39.8 38.1 35.0 35.8 47.5 24.1 47.6 47.1 62.7 174.1 212.2 43.8 101.7 71.4 50.9 51.2 54.1 21.6 139.8 91.2 89.5 23.5 75.5 59.4 70.0 77.0 143.4 86.8 121.4 62.2 58.2 98.2 47.7 83.5 49.7 91.0 21.8 35.6 80.0 99.5 125.4 51.7 61.5 82.5 50.1 42.8 83.6 24.4 19.4 109.5 69.9 85.0 204.9 259.0 79.8 56.2 157.9 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Peritubular cells: 248.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB018600: AB_675841, HPA043236: AB_2678379" "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favorable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 26.7 21.0 61.3 11.9 54.9 2.6 28.7 32.0 46.2 28.8 24.1 30.7 19.4 21.7 34.5 37.5 29.7 28.2 23.1 27.2 57.3 43.7 41.0 35.7 27.7 8.4 52.6 39.8 48.0 22.9 33.7 14.8 27.4 47.7 23.7 24.5 12.5 19.5 29.1 27.4 18.0 31.2 39.0 49.7 15.0 18.9 18.8 48.2 6.3 44.5 14.0 14.0 17.7 34.3 5.8 7.9 5.1 6.5 7.3 4.8 1.7 22.1 19.4 33.9 12.9 33.9 30.9 18.9 29.7 27.8 30.8 32.3 20.3 16.3 10.8 29.2 39.5 29.5 13.4 20.2 34.1 41.6 6.7 10.6 14.4 13.2 20.4 38.9 6.4 8.2 27.2 39.0 26.0 29.2 31.3 36.9 18.1 22.3 11.5 51.9 10.9 17.5 8.2 24.7 33.5 11.2 12.3 13.6 8.0 41.2 18.0 32.6 13.5 13.7 14.6 28.6 39.5 8.0 11.0 38.7 26.6 20.0 8.7 24.5 5.9 7.7 12.8 22.8 6.0 34.0 4.8 5.0 3.3 4.2 6.5 4.8 5.8 3.8 4.2 3.5 2.7 3.8 4.6 5.1 7.3 3.0 7.9 2.8 1.7 61.3 54.9 32.0 46.2 57.3 43.7 52.6 39.8 47.7 48.2 65.5 53.8 13.8 81.2 92.5 34.5 71.2 40.8 34.8 50.0 82.0 29.5 36.8 39.7 34.2 13.3 49.6 112.3 0.0 42.0 43.1 62.0 108.1 17.3 81.5 48.8 44.5 31.0 101.3 52.3 13.4 67.9 30.8 38.8 16.2 51.0 105.4 64.5 41.8 248.2 63.4 21.1 45.3 59.7 30.2 35.8 83.6 59.0 14.0 32.4 132.7 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease mutation, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 35000 Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 12.2 9.2 22.7 7.4 71.8 7.7 10.6 42.1 52.4 9.4 9.5 4.8 9.8 5.8 6.2 6.9 7.4 7.2 6.8 4.3 36.0 13.5 5.8 8.4 10.0 6.7 10.1 22.1 9.6 4.7 7.0 4.2 6.6 11.9 34.6 8.4 2.6 10.4 21.1 23.7 11.4 6.4 7.9 7.5 6.9 11.0 5.3 13.0 3.8 6.8 6.8 8.9 8.4 6.8 27.7 18.3 44.3 14.9 22.3 15.5 6.6 19.4 13.8 3.8 7.5 21.6 16.4 7.4 21.5 19.8 8.7 9.2 8.0 24.4 9.3 9.0 19.4 10.8 9.8 13.9 28.6 14.8 22.7 6.4 14.7 19.8 10.2 15.9 23.6 7.5 17.0 15.0 19.0 21.8 16.6 16.3 6.0 5.7 25.6 13.9 23.4 4.9 17.7 6.4 22.5 9.0 9.0 35.0 10.7 8.4 15.4 30.4 11.5 17.7 15.2 10.3 5.5 13.6 13.5 19.0 20.6 23.5 18.8 14.2 12.0 12.2 16.4 11.4 13.4 5.5 24.6 11.8 24.8 13.6 11.4 15.5 27.7 12.9 13.1 9.9 23.4 6.2 12.3 44.3 22.3 14.9 18.3 8.6 6.6 22.7 71.8 42.1 51.5 36.0 13.5 10.1 22.1 11.9 13.0 71.5 48.8 59.1 33.3 149.9 74.7 24.1 33.1 32.1 20.5 29.6 37.3 28.9 28.2 18.2 1.8 105.6 33.9 0.0 27.3 76.5 53.9 157.6 33.6 37.0 32.1 17.5 122.2 43.6 52.2 4.7 60.1 49.5 87.7 44.1 39.6 19.3 41.1 107.8 57.3 31.7 81.9 12.9 39.4 7.2 22.1 150.4 23.0 55.4 39.9 32.0 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436428-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 133.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria NA NA Mitochondria "HPA008233: AB_1855661, HPA008823: AB_2668148" "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavorable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 17.3 16.1 40.0 11.7 36.3 7.6 22.5 44.5 42.7 13.4 16.1 7.9 9.5 10.1 17.0 15.0 14.0 12.3 12.0 16.7 39.7 20.5 11.9 9.1 9.8 13.1 18.2 40.7 17.2 10.5 19.3 16.8 10.6 21.1 16.8 12.8 9.5 10.4 17.6 133.0 10.9 9.4 23.0 18.1 10.0 10.7 11.6 11.9 8.4 10.1 10.0 14.3 14.1 14.4 4.2 5.7 4.8 3.8 4.5 10.6 2.7 19.1 10.6 19.0 19.6 27.3 37.9 9.1 17.6 24.2 17.3 17.2 6.7 9.8 17.0 5.7 25.4 8.2 10.3 15.3 13.5 24.4 23.8 12.5 7.2 9.6 12.7 16.3 16.0 15.1 26.8 16.3 16.3 21.9 31.9 11.9 14.9 9.0 20.0 34.8 6.0 14.3 14.8 7.7 8.4 31.0 9.6 10.3 8.0 16.8 9.3 10.2 11.8 10.3 25.8 12.9 16.5 19.4 15.5 13.0 13.8 12.7 11.0 23.8 13.4 36.5 11.9 17.1 23.1 7.8 3.2 2.9 4.8 6.2 3.8 7.3 4.2 6.7 6.6 3.0 3.0 5.3 7.9 1.7 4.5 2.3 5.7 10.6 2.7 40.0 36.3 44.5 42.7 39.7 20.5 18.2 40.7 21.1 11.9 3.0 11.0 18.2 26.7 22.8 52.0 42.6 10.2 13.4 11.4 17.4 19.6 17.9 53.0 15.6 5.9 18.3 10.2 0.0 16.6 13.6 21.4 23.8 20.7 12.3 17.9 36.5 40.9 17.2 30.2 7.6 31.1 18.8 25.3 27.1 12.3 32.9 15.6 14.4 27.3 25.6 28.0 6.5 37.1 38.5 44.0 27.6 18.5 15.7 14.4 19.3 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles NA NA Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favorable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 18.0 8.3 6.9 13.7 8.1 15.2 21.1 11.9 12.0 10.3 10.2 10.9 3.7 6.1 13.4 7.8 11.6 9.0 10.7 27.5 7.6 7.3 8.9 8.2 16.5 22.3 7.7 4.9 10.1 9.9 13.7 15.1 12.7 9.9 11.1 7.1 20.7 15.5 6.0 52.4 9.1 9.8 13.5 7.9 14.1 9.5 41.6 6.9 6.8 11.5 13.2 20.0 14.7 11.0 15.5 4.0 6.6 2.9 11.9 16.0 3.9 5.5 4.1 3.6 4.4 9.7 12.1 5.3 7.7 13.6 11.5 12.8 2.3 3.5 21.0 9.5 11.9 19.2 3.9 8.4 7.7 14.7 12.0 4.5 4.5 4.7 6.7 13.1 3.2 7.4 7.3 10.7 7.7 7.9 12.3 9.9 10.3 8.8 28.0 12.8 2.6 7.5 5.3 2.6 5.7 5.6 24.7 8.6 6.9 10.7 5.2 2.6 6.1 5.8 3.4 7.9 7.2 2.3 5.4 10.6 17.9 3.8 27.1 5.9 14.0 16.9 22.0 9.5 4.3 11.8 3.4 1.6 6.6 11.4 2.0 8.7 15.5 12.9 16.0 3.2 13.9 12.4 10.1 0.4 11.9 2.9 4.0 10.1 3.9 6.9 8.1 11.9 12.0 7.6 7.3 7.7 4.9 9.9 6.9 6.0 3.2 39.8 18.1 14.7 9.7 7.0 12.7 2.7 3.4 7.0 45.2 15.0 6.6 12.0 88.7 24.7 7.2 0.0 18.7 19.5 22.6 23.7 3.5 6.8 11.9 3.2 9.9 23.9 11.3 9.4 20.8 18.5 27.0 43.3 3.1 12.3 15.5 9.9 20.1 10.4 50.5 32.3 26.2 71.2 27.9 9.9 11.8 43.6 6.0 23.0 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085377 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 24.7 26.6 13.5 26.1 14.1 26.7 18.6 16.0 15.9 19.2 28.4 14.5 20.5 22.5 19.2 28.4 39.1 17.7 31.9 28.5 12.6 12.1 28.9 52.3 27.4 25.3 12.5 12.8 22.5 26.3 23.9 16.2 51.6 11.9 18.3 17.4 18.8 22.0 14.9 26.0 26.1 38.8 15.9 11.9 36.2 22.6 39.0 9.5 59.7 27.1 26.5 37.9 22.2 21.1 19.5 30.3 57.3 28.2 12.4 23.6 12.0 30.8 34.6 23.1 32.2 21.9 18.5 36.0 27.5 30.7 36.2 40.2 30.4 40.3 24.0 35.4 32.4 23.6 25.2 28.6 34.1 21.4 30.1 51.2 16.3 21.5 67.2 33.3 22.9 30.9 26.8 30.2 33.0 21.0 21.7 42.0 31.3 31.8 22.0 27.6 88.9 39.9 41.8 44.0 24.5 18.4 44.7 24.0 41.8 34.2 31.8 22.5 33.3 13.5 40.8 23.5 20.2 37.6 39.0 26.7 21.2 22.3 17.1 21.1 37.8 41.5 28.1 30.2 29.6 25.6 21.4 26.9 57.3 18.3 28.2 13.1 17.0 19.2 20.6 30.3 19.5 17.2 15.2 56.9 12.4 24.5 23.5 23.6 12.0 13.5 14.1 16.0 15.9 12.6 12.1 12.5 12.8 11.9 9.5 47.6 33.1 81.7 96.8 130.7 20.0 9.3 89.2 54.9 23.9 73.3 27.5 268.8 134.3 208.0 127.6 84.2 174.4 0.0 169.7 278.1 71.4 111.6 69.1 85.6 210.3 33.4 120.5 58.9 91.3 98.3 58.1 124.3 75.9 252.5 114.3 41.8 254.7 168.4 49.1 156.3 25.7 71.1 65.1 231.9 141.6 150.8 352.1 111.4 129.3 192.9 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46346994-46392981 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol NA NA 47000 "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: AB_2683278" "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 18.9 24.7 23.0 18.1 28.8 13.4 15.9 25.2 50.8 20.4 21.1 19.4 15.2 18.0 23.0 15.2 20.1 27.8 20.5 48.2 20.8 23.9 22.6 22.1 17.4 19.3 21.9 29.8 16.7 21.5 26.3 23.9 17.3 34.5 19.5 17.5 19.7 21.0 21.4 40.8 16.4 15.3 23.5 16.2 21.7 20.6 19.0 15.3 15.6 18.1 20.5 16.1 17.1 18.1 10.6 11.1 1.9 14.1 14.0 19.8 8.9 19.5 36.8 22.0 16.6 16.6 17.8 10.2 24.4 19.8 29.6 26.7 26.4 15.6 30.1 13.3 17.7 16.2 16.1 28.9 28.8 8.9 20.8 39.3 25.0 27.0 18.7 18.6 33.8 17.5 16.2 13.6 20.8 15.5 11.4 25.4 25.7 24.0 15.5 16.8 21.2 18.9 63.4 16.6 35.1 20.1 28.2 19.0 24.1 17.7 26.8 31.3 23.0 20.4 26.0 8.7 10.4 16.3 21.6 21.1 13.0 21.6 9.6 25.5 12.5 28.7 36.0 13.9 28.4 21.6 0.0 6.8 1.9 19.8 12.1 12.7 10.6 9.2 15.3 11.1 8.7 8.9 12.0 0.1 14.0 14.1 7.9 9.3 8.9 23.0 28.8 25.2 50.8 20.8 23.9 21.9 29.8 34.5 15.3 6.0 12.2 13.4 14.5 8.4 19.1 4.7 50.9 9.4 10.3 15.7 15.7 20.7 28.2 26.1 1.0 13.4 17.7 0.0 16.8 30.9 14.6 11.3 4.6 22.8 19.0 15.9 14.3 30.7 10.8 1.7 16.1 7.6 15.1 14.4 15.1 19.1 22.4 11.5 17.3 17.3 16.9 38.8 20.6 14.6 39.2 11.5 21.5 17.0 21.3 8.4 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain NA NA "HPA050940: AB_2681283" "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 21.7 20.1 20.1 15.7 24.5 24.8 21.2 20.8 26.2 17.0 19.1 25.9 15.1 13.9 15.6 17.2 21.2 14.0 12.9 15.3 19.8 16.6 22.8 17.8 16.3 21.5 20.1 16.1 17.5 27.7 21.3 17.3 17.6 17.8 14.5 21.8 16.8 26.9 14.6 50.5 19.3 17.3 16.3 22.6 19.4 16.5 22.8 23.7 34.1 22.2 20.5 24.0 13.8 15.6 17.3 14.8 32.2 19.5 13.9 23.3 13.8 14.1 10.3 18.8 17.8 20.2 16.9 19.0 15.0 16.3 22.2 18.6 16.5 15.0 20.4 11.7 20.1 18.9 28.9 25.4 16.3 25.8 18.2 12.3 16.7 16.2 14.6 16.6 29.1 23.2 13.9 22.4 18.2 17.4 17.1 20.7 23.4 19.5 23.7 23.9 21.0 27.4 18.4 17.5 39.6 19.2 22.4 28.5 27.2 18.8 14.3 19.5 19.3 26.8 21.6 17.4 16.7 33.4 18.4 20.0 13.7 13.1 26.5 19.9 26.2 47.2 27.0 18.4 19.1 22.2 27.2 13.2 21.4 14.7 17.4 18.0 17.3 18.9 16.6 14.8 13.3 18.9 17.5 32.2 13.9 19.5 10.7 23.3 13.8 20.1 24.5 20.8 26.2 19.8 16.6 20.1 16.1 17.8 23.7 38.7 27.8 41.7 45.6 68.7 15.2 30.8 35.7 21.4 23.9 26.2 7.9 40.2 48.0 40.6 102.7 41.4 34.6 23.3 47.6 45.3 30.1 41.0 43.9 36.1 46.7 14.3 46.0 46.6 52.3 56.7 27.6 48.9 42.2 46.9 41.6 28.7 41.6 38.6 33.9 54.9 12.9 51.8 44.8 93.3 43.0 76.5 72.9 49.0 37.9 48.2 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40071461-40097727 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Hofbauer cells: 247.2;Kupffer cells: 246.8;Macrophages: 282.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 88.0;THP-1: 163.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 130000 "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 33.3 27.1 37.6 31.0 41.5 33.3 39.7 35.2 41.0 30.3 21.0 31.5 17.2 12.9 31.3 19.4 18.5 20.7 23.2 18.1 32.7 35.8 29.4 18.4 47.3 48.5 35.3 29.1 24.7 17.4 30.4 21.2 25.9 34.6 28.0 26.0 26.3 22.1 23.6 8.3 13.8 16.6 36.5 33.6 61.3 17.9 13.8 29.1 19.8 18.7 14.4 30.0 23.0 19.8 9.3 77.4 59.9 90.0 7.2 19.1 91.6 10.3 7.0 11.3 6.3 13.6 11.6 22.1 5.8 10.4 13.9 17.2 40.1 17.3 11.8 11.3 6.0 11.5 18.1 17.5 10.3 19.1 14.8 18.0 6.2 17.2 19.8 15.4 13.8 14.9 10.9 11.3 11.1 10.3 7.8 18.7 10.1 14.3 17.1 7.8 20.6 7.9 10.3 21.2 15.8 10.8 8.9 15.2 20.5 9.7 18.4 9.0 9.6 11.3 88.0 35.0 11.1 12.7 163.5 6.6 6.8 14.6 6.3 17.1 15.4 32.3 11.3 8.7 33.8 12.3 6.2 90.0 48.2 9.9 77.6 11.8 9.3 14.7 11.5 77.4 9.2 19.1 14.7 59.9 7.2 58.3 7.6 16.8 91.6 37.6 41.5 35.2 41.0 32.7 35.8 35.3 29.1 34.6 29.1 26.8 50.8 34.5 72.3 35.1 45.4 13.0 38.2 38.8 47.8 36.6 15.7 48.8 5.0 52.1 40.9 45.0 3.0 23.3 36.9 52.5 46.0 47.6 82.1 8.3 247.2 23.8 19.1 48.5 246.8 54.3 29.1 282.7 64.1 155.1 8.2 108.8 23.0 7.0 37.1 15.4 24.1 19.4 53.3 13.7 37.9 23.8 34.4 40.8 10.3 29.4 PPTC7 TA-PP2C ENSG00000196850 "PTC7 protein phosphatase homolog" Q8NI37 12 110533245-110583320 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.8" "Cell type enhanced" "Detected in all" 4 "Cardiomyocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA039335: AB_10805474, HPA040614: AB_10795526" "unprognostic (2.44e-1)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (9.44e-2)" "unprognostic (2.38e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.43e-5)" "prognostic unfavorable (6.76e-4)" "unprognostic (1.09e-1)" "prognostic favorable (4.48e-5)" "unprognostic (5.34e-2)" "unprognostic (2.83e-1)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" 10.4 15.3 6.5 10.3 9.6 26.2 10.3 8.3 12.9 9.7 11.8 5.7 4.9 7.5 9.3 4.6 12.6 7.8 8.8 35.3 9.0 9.0 12.6 11.9 13.1 10.9 10.4 6.8 8.9 7.5 13.0 12.7 6.9 15.3 7.7 9.8 8.0 12.9 8.2 53.8 13.4 11.7 13.1 7.4 9.4 8.4 8.2 6.5 16.1 8.0 15.5 13.1 12.4 12.4 2.1 1.4 6.1 1.7 1.7 2.4 0.6 12.2 7.0 6.0 6.3 15.0 13.2 8.6 5.6 7.5 6.2 6.2 7.9 4.8 21.5 5.9 5.5 8.9 11.9 12.0 13.1 12.6 15.6 10.0 19.0 7.5 8.5 14.3 21.0 15.7 11.4 21.6 8.8 25.9 9.3 11.7 15.0 14.1 6.1 10.0 3.1 18.5 18.0 8.5 6.6 13.1 15.5 8.1 13.1 25.7 13.7 9.7 7.6 10.7 14.8 12.4 6.1 7.0 11.3 13.4 5.7 6.1 17.3 9.5 17.8 19.7 24.0 9.6 11.6 11.2 0.1 1.7 1.3 2.3 1.5 2.4 1.3 1.9 1.8 1.3 2.1 2.2 1.9 6.1 1.7 1.1 1.4 1.3 0.6 6.5 9.6 8.3 12.9 9.0 9.0 10.4 6.8 15.3 6.5 20.8 21.2 21.7 47.9 81.6 8.5 96.6 15.3 25.4 22.7 8.7 13.7 6.3 14.9 6.8 29.6 22.2 18.4 23.3 7.1 7.0 37.6 42.4 23.1 24.9 15.0 12.7 16.1 14.7 25.1 17.5 10.6 19.9 32.1 10.0 14.2 3.9 11.1 14.4 9.2 10.5 24.1 12.9 39.1 12.5 22.5 91.1 5.6 20.8 13.8 64.3 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82823502-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Ito cells: 392.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 99.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" NA NA 34000000 Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 32.6 45.9 25.0 21.5 22.2 13.1 69.5 19.4 23.8 38.8 17.9 17.9 27.6 11.0 30.7 35.5 32.2 24.6 25.6 66.3 25.8 18.9 52.4 52.5 38.1 95.1 27.0 14.8 27.8 23.4 30.6 19.3 59.8 34.9 25.1 18.4 25.1 38.1 34.5 10.3 26.2 15.7 32.8 45.0 25.1 16.8 17.4 17.7 9.8 27.9 24.2 31.7 39.4 30.1 13.1 50.0 31.2 27.9 12.1 6.2 14.7 7.5 8.3 12.8 25.7 99.0 36.4 15.0 16.2 28.9 15.5 22.8 20.5 15.7 10.9 23.7 23.5 17.6 12.0 11.6 10.7 18.2 9.7 8.4 7.8 11.6 12.7 18.5 7.0 28.6 26.5 8.3 16.2 15.3 38.1 51.4 6.0 8.3 15.4 15.9 3.4 1.0 25.0 7.4 18.5 7.7 5.7 22.2 13.0 21.7 14.0 5.3 11.6 22.2 12.8 9.1 19.7 15.4 9.6 13.3 18.3 18.4 15.8 7.9 14.5 24.6 9.8 7.5 8.5 9.4 15.5 26.4 17.4 5.3 27.9 6.1 9.9 5.3 5.8 50.0 13.1 4.4 6.2 31.2 12.1 21.2 8.9 5.0 14.7 25.0 22.2 19.4 23.8 25.8 18.9 27.0 14.8 34.9 17.7 17.9 14.6 43.2 35.5 27.8 10.0 19.8 43.3 5.3 12.5 59.3 2.0 49.3 24.9 28.4 24.0 120.7 4.9 0.0 10.6 99.1 49.9 26.3 12.7 56.8 72.6 15.9 18.9 392.8 149.3 39.4 40.9 76.3 67.4 54.1 18.6 57.0 10.0 7.0 43.5 76.8 4.3 64.7 26.8 23.6 5.7 30.6 44.3 25.4 19.9 33.8 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477266-173488807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 180000000 "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 80.0 42.1 32.8 30.8 38.9 21.8 106.3 19.8 32.8 27.2 46.7 37.4 35.8 12.1 30.8 54.1 39.9 40.2 22.3 70.5 29.0 23.9 45.9 116.1 29.2 37.5 34.0 28.2 31.5 39.3 63.9 19.1 36.9 30.3 40.0 56.0 21.3 22.6 35.4 128.0 25.7 20.2 40.5 19.7 23.1 33.2 44.9 24.1 17.4 46.9 68.6 25.7 36.5 46.2 17.2 37.9 14.3 23.9 12.0 25.0 30.6 52.1 16.0 26.6 29.5 103.2 50.5 22.5 106.5 36.3 44.5 31.6 30.2 35.1 33.9 34.1 87.2 16.4 30.5 34.8 34.3 36.2 29.8 32.1 22.5 27.4 34.1 58.2 23.5 7.4 41.8 34.8 24.4 34.2 28.0 43.6 14.2 50.0 7.0 50.5 10.7 15.9 31.0 58.5 28.7 99.6 19.1 30.8 34.6 66.6 11.9 12.4 23.0 36.7 43.2 24.4 40.0 36.5 33.2 29.3 17.3 19.9 26.2 28.9 10.6 15.7 27.9 20.8 20.5 15.8 13.9 23.9 12.9 17.0 20.6 18.9 17.2 17.6 21.1 29.3 13.6 23.2 25.0 14.3 12.0 17.5 37.9 20.4 30.6 32.8 38.9 19.8 32.8 29.0 23.9 34.0 28.2 30.3 24.1 163.8 131.5 140.0 350.9 209.2 31.5 477.5 249.7 195.4 161.5 263.5 27.5 589.1 729.5 163.2 193.0 183.6 264.7 256.9 175.5 640.5 290.3 337.6 341.6 875.0 302.1 42.9 136.4 174.3 152.8 441.3 315.2 140.2 173.7 230.0 253.4 390.8 159.2 306.9 391.7 634.8 41.0 181.1 254.2 113.1 58.3 231.0 805.7 161.9 278.6 280.8 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105277565-105403084 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1400000 Cytosol "CAB025414: , HPA031388: AB_2673855, HPA031389: AB_2673856, HPA031390: AB_2673857" "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 13.0 14.2 10.1 22.2 10.1 10.4 36.2 10.9 24.9 11.9 27.2 5.2 11.2 20.2 13.2 10.9 16.4 10.5 15.0 19.0 8.8 7.1 8.9 14.6 23.9 31.4 8.3 15.4 13.6 18.8 16.1 11.1 15.4 9.7 9.4 33.0 8.9 14.9 11.5 58.0 24.2 19.0 15.3 8.5 11.9 14.0 20.1 8.8 17.4 10.2 18.5 13.3 18.2 21.0 8.3 15.3 7.1 18.7 16.6 16.3 11.2 11.0 13.5 14.5 16.2 34.3 20.3 14.3 14.9 14.0 19.7 20.9 17.2 7.0 14.2 14.7 17.5 18.2 17.2 21.3 43.6 22.4 21.4 20.8 19.0 11.4 19.6 13.2 19.2 13.9 18.8 26.6 14.1 36.5 14.9 18.3 25.1 32.4 25.4 23.8 18.0 12.8 19.5 14.0 21.4 13.6 19.8 24.9 9.2 14.7 26.4 19.0 27.1 13.1 21.9 10.4 19.2 9.4 30.8 18.4 9.0 12.6 11.3 18.3 7.4 4.9 18.6 16.0 20.9 28.1 4.8 13.6 7.1 16.0 15.4 15.6 8.3 13.7 16.3 15.3 6.8 12.9 15.2 0.7 16.6 18.7 6.5 12.0 11.2 10.1 10.1 10.9 24.9 8.8 7.1 8.3 15.4 9.7 8.8 3.0 7.0 6.1 5.7 9.6 5.3 13.2 5.1 1.4 7.9 7.0 13.7 16.0 5.0 9.1 0.9 9.0 15.7 0.0 10.2 27.4 9.0 4.3 13.8 13.9 13.4 12.7 18.6 9.2 15.8 2.4 10.0 10.0 5.0 18.0 33.1 3.3 12.9 17.3 8.5 6.7 9.5 0.0 12.3 2.1 17.9 7.4 56.8 11.3 34.9 7.6 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429246 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 137.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 348.7" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 29.2" "Lineage enriched" "Detected in many" 9 "dendritic cells: 29.2" "Cell line enriched" "Detected in some" 16 "Hep G2: 58.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005550, CAB016721, CAB016792" Supported "Secreted to blood" NA NA 6400000000 "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.2 4.2 137.5 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 29.2 3.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 0.0 0.3 0.0 0.1 3.7 0.0 0.1 0.0 0.0 0.0 0.0 2.8 58.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 29.2 0.0 0.1 0.4 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.4 0.0 0.0 0.0 4.3 0.6 0.7 0.0 0.3 40.8 1.4 0.0 0.0 0.0 0.0 5.0 0.4 0.0 0.0 2.6 0.0 0.2 0.0 0.2 0.0 0.0 348.7 3.9 0.0 9.9 9.8 4.5 0.0 0.0 1.7 0.0 0.0 8.1 0.0 1.2 8.7 0.0 78.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.5 1.5 0.1 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1708 "pancreas: 3057.4" "Cell type enriched" "Detected in some" 17 "Exocrine glandular cells: 49265.4" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 2.7;OE19: 10.1;RPMI-8226: 5.4;U-2 OS: 3.2;U-266/84: 1.9" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 26000000000 Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" 0.4 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 3057.4 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 0.0 1.7 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 10.1 0.0 0.0 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.1 0.0 1.9 0.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.0 0.0 49265.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 208.2 0.0 0.5 2827.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 708 "pancreas: 6267.9" "Cell type enriched" "Detected in some" 6 "Exocrine glandular cells: 92348.3" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Group enriched" "Detected in some" 6 "basophil: 5.6;T-reg: 5.1" "Group enriched" "Detected in many" 6 "granulocytes: 5.6;T-cells: 5.1" "Cell line enhanced" "Detected in some" "OE19: 11.6;RPMI-8226: 37.4;U-2 OS: 8.1" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 27000000000 Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6267.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 5.6 0.0 0.7 5.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 2.4 0.2 0.0 0.0 0.0 1.1 0.0 11.6 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.5 2.1 0.0 1.6 0.2 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 307.0 0.0 0.0 0.0 0.0 92348.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 608.7 0.0 0.0 14696.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750466-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "pancreas: 984.9" "Cell type enhanced" "Detected in many" 19 "Enterocytes: 998.3;Exocrine glandular cells: 1691.4;Pancreatic endocrine cells: 545.2;Paneth cells: 388.3" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 82 "basophil: 39.0" "Lineage enriched" "Detected in single" 82 "granulocytes: 39.0" "Group enriched" "Detected in some" 5 "OE19: 46.2;PC-3: 121.2" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 490000000 Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 0.3 0.3 1.6 1.7 1.5 0.2 0.2 2.8 4.2 0.9 8.2 0.0 0.0 2.8 0.2 0.2 2.9 0.2 4.8 0.4 1.2 0.7 0.3 0.4 0.2 0.2 0.3 1.6 0.7 984.9 0.2 0.1 0.2 2.3 0.2 2.3 0.0 0.6 0.2 0.2 2.0 23.9 0.3 0.2 0.2 0.8 0.3 0.0 0.0 0.2 6.6 3.5 0.2 1.3 0.0 0.1 39.0 0.4 0.1 0.3 0.1 1.7 1.9 0.1 0.0 0.0 0.9 0.0 4.8 1.1 0.5 0.2 4.7 0.4 0.0 0.0 2.1 0.0 2.1 0.0 4.4 1.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 15.8 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 46.2 121.2 0.0 0.0 0.0 0.0 0.2 0.0 12.2 0.0 0.0 0.0 0.1 0.0 0.0 10.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 39.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 1.6 1.5 2.8 4.2 1.2 0.7 0.3 1.6 2.3 0.0 0.0 0.0 2.2 0.2 50.7 0.2 0.9 48.4 0.0 0.0 1.8 0.0 0.0 3.3 13.8 29.4 1.1 998.3 0.0 1691.4 0.0 0.4 7.0 9.2 1.0 0.0 0.0 184.8 1.3 0.3 56.5 1.4 1.2 6.8 10.0 156.0 0.0 545.2 388.3 0.7 6.7 0.0 0.0 3.1 0.5 0.4 117.2 0.1 0.0 282.9 19.5 PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 27.2" "Group enriched" "Detected in some" 128 "Early spermatids: 636.2;Late spermatids: 161.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 22 "RH-30: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 636.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 0.0 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840960-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 167.3" "Cell type enhanced" "Detected in some" 23 "Cholangiocytes: 2.5;Kupffer cells: 1.2" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enriched" "Detected in some" 5 "THP-1: 151.5" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" NA NA 120000 Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.3 0.2 0.9 0.2 1.0 167.3 0.2 0.0 2.3 0.2 0.2 0.7 0.0 0.2 0.2 0.2 0.2 0.2 0.2 31.0 0.3 0.6 0.2 1.7 8.1 3.5 0.1 0.1 0.4 0.2 0.2 0.8 4.2 0.8 0.2 0.2 0.3 0.3 0.2 0.5 0.3 0.2 0.2 0.0 25.5 0.2 0.2 0.1 35.0 0.9 0.0 0.2 0.2 0.0 0.0 0.0 1.9 0.1 0.0 0.2 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 6.8 0.9 1.0 0.0 2.3 0.3 0.6 0.1 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 7 "Alveolar cells type 2: 8.8;Collecting duct cells: 10.4;Proximal tubular cells: 6.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 62.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol NA NA 210000 Cytosol "HPA028411: AB_10603229" "unprognostic (6.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (2.12e-3)" "unprognostic (7.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.92e-2)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" 9.3 9.7 9.3 8.8 11.6 3.7 16.0 15.7 16.4 15.0 12.5 10.9 16.2 11.7 17.9 15.7 11.5 15.6 12.8 31.3 10.5 10.3 18.0 12.8 10.1 11.8 11.9 9.2 17.1 16.2 16.5 16.2 7.2 8.8 12.2 14.0 12.7 13.3 18.2 24.4 10.5 11.8 14.7 7.9 11.0 10.5 16.3 8.6 15.0 41.6 8.5 12.9 13.8 13.6 12.1 9.5 14.7 8.9 14.3 19.0 18.3 3.9 4.2 7.5 7.2 9.4 2.6 4.2 1.9 4.1 7.0 6.1 5.1 4.7 8.1 8.2 2.5 2.0 5.7 7.3 4.9 5.6 8.7 8.3 9.5 4.4 7.4 5.1 6.2 4.8 3.2 9.3 3.7 3.6 5.8 3.3 10.7 7.4 6.8 3.3 9.4 9.5 5.1 7.0 14.3 5.5 8.7 4.8 7.7 5.0 5.4 10.9 8.9 6.3 8.8 5.8 11.1 12.1 9.4 2.3 2.5 3.0 2.7 2.9 16.6 14.0 62.0 2.4 4.7 6.2 12.5 6.4 13.4 14.0 6.0 16.9 12.1 15.5 15.7 9.5 11.6 19.0 15.0 14.7 14.3 8.9 5.1 14.5 18.3 9.3 11.6 15.7 16.4 10.5 10.3 11.9 9.2 8.8 8.6 6.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.7 10.4 0.0 3.6 0.0 4.9 0.0 0.0 0.0 0.0 4.9 3.8 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 2.8 0.0 0.0 5.1 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 PSMA1 "HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30" ENSG00000129084 "Proteasome subunit alpha 1" P25786 11 14504874-14643635 "Enzymes, Predicted intracellular proteins" Immunity "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB033765, HPA037646, HPA043891" Supported Enhanced Nucleoplasm NA NA 27000000 Nucleoplasm "CAB033765: AB_2253026, HPA037646: AB_10670386, HPA043891: AB_2678718" "unprognostic (1.72e-2)" "unprognostic (4.97e-2)" "unprognostic (7.33e-2)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (6.66e-3)" "prognostic unfavorable (3.79e-5)" "unprognostic (3.28e-3)" "unprognostic (7.44e-2)" "unprognostic (3.43e-3)" "unprognostic (8.27e-3)" "unprognostic (8.77e-2)" "prognostic unfavorable (4.03e-11)" "unprognostic (1.93e-1)" "unprognostic (1.69e-1)" "unprognostic (4.66e-2)" "unprognostic (1.23e-2)" 46.6 46.3 33.7 36.0 40.2 45.7 39.0 28.3 42.7 33.4 35.5 23.1 37.4 37.3 42.1 43.1 43.7 33.0 32.2 55.4 31.7 34.1 47.8 61.0 38.8 42.3 32.0 32.4 34.0 35.6 28.2 39.4 55.2 36.9 35.6 42.4 32.9 34.9 37.1 86.6 35.3 42.7 39.0 26.7 45.8 37.3 31.6 25.9 53.0 45.5 62.8 42.2 41.5 31.7 24.2 55.4 20.9 42.3 30.5 35.7 45.2 67.4 47.7 40.0 47.9 39.9 40.2 33.4 39.9 52.5 60.9 50.1 41.3 85.2 59.0 44.2 42.1 55.8 50.9 45.6 49.5 57.7 57.3 67.7 36.8 31.7 48.7 52.4 61.0 48.1 38.9 29.5 33.0 69.2 44.5 59.5 47.6 69.0 49.8 54.1 44.7 55.5 45.9 33.4 57.6 71.2 37.6 59.3 36.7 52.9 47.9 33.0 20.8 42.5 47.7 35.6 43.1 28.4 37.3 47.0 39.9 37.5 69.8 48.7 21.8 58.3 52.8 59.0 48.6 50.9 20.9 42.3 11.0 24.3 31.1 32.3 24.2 28.3 27.2 55.4 20.6 25.7 25.0 9.4 30.5 29.4 31.3 35.7 45.2 33.7 40.2 28.3 42.7 31.7 34.1 32.0 32.4 36.9 25.9 77.4 91.8 78.9 188.2 127.0 44.8 0.0 73.9 65.6 95.5 83.7 17.7 398.7 217.2 193.4 40.4 121.2 89.1 70.0 203.0 301.8 137.7 149.4 72.1 111.7 261.1 54.0 38.6 87.8 164.2 23.5 107.9 156.0 136.7 273.3 81.1 94.3 195.2 111.4 119.9 182.7 40.0 84.1 135.9 126.7 65.4 132.7 524.5 142.0 111.1 217.3 PSMA2 "HC3, MU, PMSA2" ENSG00000106588 "Proteasome subunit alpha 2" P25787 7 42916857-42932223 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "monocytes: 569.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA008188 Uncertain NA NA 80000000 "HPA008188: AB_1855819" "unprognostic (9.40e-3)" "unprognostic (2.08e-2)" "unprognostic (8.21e-2)" "unprognostic (2.23e-2)" "unprognostic (4.13e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.01e-2)" "unprognostic (9.25e-2)" "prognostic favorable (6.73e-5)" "unprognostic (1.77e-1)" "unprognostic (3.42e-1)" "unprognostic (1.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (6.38e-2)" "unprognostic (4.24e-2)" 24.7 32.2 25.3 24.6 29.5 29.7 29.4 19.6 22.0 19.2 25.6 13.4 26.0 29.8 22.6 26.2 31.1 19.4 20.5 35.8 22.3 16.6 33.3 90.9 23.2 27.4 27.2 17.6 20.8 28.8 12.0 18.8 33.7 29.2 24.5 26.0 10.1 21.7 19.6 57.2 22.4 33.1 22.0 21.4 26.6 27.8 18.6 23.5 42.2 29.9 44.6 29.9 22.8 20.2 46.2 54.1 81.7 47.4 36.7 56.7 75.0 32.1 34.6 40.6 49.1 21.7 24.4 30.3 28.5 33.4 46.1 49.4 51.5 53.0 59.9 50.9 25.2 72.2 45.1 41.9 39.5 53.2 43.2 33.3 30.5 46.9 54.3 23.2 51.7 33.1 22.4 28.9 35.5 21.2 33.0 43.3 36.9 61.4 36.8 36.8 37.8 46.1 101.8 80.4 53.2 43.0 45.1 39.5 58.8 44.3 44.5 33.0 33.6 31.0 71.3 31.1 57.6 51.8 60.6 30.9 27.4 49.9 29.2 56.1 48.0 72.7 98.0 46.5 65.8 77.2 59.0 45.7 81.7 35.2 45.2 40.4 46.2 43.4 40.5 48.5 40.7 39.0 41.3 23.3 36.7 47.4 54.1 56.7 75.0 25.3 29.5 19.6 22.0 22.3 16.6 27.2 17.6 29.2 23.5 83.4 79.1 145.3 58.9 0.1 28.0 0.0 124.9 107.1 122.8 90.7 21.6 258.4 144.2 278.9 15.8 73.3 147.1 70.0 330.5 246.8 63.2 74.2 161.7 195.1 170.9 27.0 148.7 112.3 163.6 12.0 73.4 114.0 0.0 569.9 160.7 54.7 284.0 133.3 79.5 175.7 38.7 129.4 0.0 98.4 110.0 0.0 233.4 138.4 230.0 89.8 PSMA3 HC8 ENSG00000100567 "Proteasome subunit alpha 3" P25788 14 58244831-58272012 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000905 Approved NA NA 13000000 "HPA000905: AB_1079702" "unprognostic (3.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.17e-1)" "unprognostic (2.19e-2)" "unprognostic (4.91e-1)" "unprognostic (5.79e-2)" "unprognostic (1.97e-3)" "unprognostic (1.27e-1)" "unprognostic (7.92e-2)" "unprognostic (7.36e-3)" "unprognostic (1.65e-2)" "unprognostic (7.57e-2)" "unprognostic (1.83e-3)" "unprognostic (2.33e-2)" "unprognostic (6.47e-2)" "prognostic favorable (2.91e-4)" "unprognostic (2.16e-1)" 26.6 41.5 21.3 27.7 25.0 24.3 28.7 16.2 25.1 23.3 26.5 17.5 34.3 27.7 25.4 46.3 33.5 23.4 21.1 55.8 24.2 22.6 51.2 59.6 28.0 31.9 23.2 20.3 23.5 25.1 20.0 30.8 50.6 28.3 24.7 28.9 17.5 25.0 27.7 68.6 18.1 34.4 27.0 22.4 33.9 26.9 15.9 15.8 32.5 37.6 50.6 31.2 32.0 20.5 36.1 50.7 31.2 40.3 38.0 45.9 36.1 67.7 42.3 42.0 34.5 33.1 31.0 54.1 35.9 40.2 50.3 50.6 62.4 56.4 57.0 66.6 32.4 40.6 46.7 47.9 38.3 59.1 50.0 29.4 39.1 32.0 70.3 62.8 62.9 33.6 26.4 27.7 34.9 33.3 30.5 59.0 46.4 36.9 33.8 40.3 77.1 54.9 60.9 28.5 55.2 64.1 46.6 54.5 42.2 72.4 67.1 39.7 19.8 31.8 50.7 34.9 41.9 52.8 47.2 37.7 29.4 57.4 33.0 47.8 13.7 25.4 58.9 42.4 49.4 35.4 31.2 34.3 20.6 32.4 40.3 40.6 36.1 39.7 38.1 37.9 25.6 32.4 37.2 20.1 38.0 33.7 50.7 45.9 36.1 21.3 25.0 16.2 25.1 24.2 22.6 23.2 20.3 28.3 15.8 110.2 101.7 83.4 140.0 105.3 37.2 101.5 73.9 100.4 96.7 83.7 33.4 328.8 140.9 209.6 19.7 104.1 81.8 46.7 200.7 212.5 105.9 111.5 93.5 140.1 163.4 39.7 61.7 64.4 52.6 19.2 101.2 107.2 102.9 276.9 57.4 65.3 175.7 61.9 99.7 236.8 67.1 97.0 101.3 102.6 54.3 92.6 337.4 83.0 79.8 145.5 PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome subunit alpha 4" P25789 15 78540405-78552419 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported Nucleoplasm,Vesicles,Cytosol No No 12000000 "Nucleoplasm, Cytosol" Vesicles "CAB004973: AB_425627, HPA055466: AB_2682824, HPA060613: AB_2684332" "unprognostic (1.80e-1)" "unprognostic (7.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.71e-2)" "unprognostic (5.35e-2)" "unprognostic (6.26e-3)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "unprognostic (2.08e-3)" "unprognostic (2.75e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (6.74e-10)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.78e-3)" "unprognostic (6.32e-3)" 41.2 38.8 24.9 36.7 25.8 33.4 33.0 25.3 37.5 32.4 38.0 17.9 23.7 39.4 35.3 32.5 49.9 27.1 24.4 37.7 29.8 27.6 55.7 76.3 37.4 45.1 25.5 26.9 31.2 24.4 20.2 25.9 55.4 33.8 35.3 41.3 19.1 26.0 25.0 60.3 26.3 49.1 36.6 28.1 45.5 31.5 36.5 21.4 61.6 42.6 75.0 44.8 41.3 28.3 29.4 61.9 31.4 75.6 37.7 40.0 61.4 40.8 59.2 51.2 45.1 32.4 30.6 40.2 38.4 30.9 47.4 50.8 61.4 59.6 89.1 56.8 35.3 53.1 55.9 103.3 41.6 45.8 36.5 72.0 74.8 44.3 49.5 52.5 76.0 46.2 24.7 26.1 39.8 39.7 29.2 51.0 49.1 80.2 35.0 38.6 58.7 51.2 71.4 48.2 47.5 34.8 44.6 67.8 29.8 47.9 71.5 45.2 33.0 61.6 45.0 46.8 66.1 41.6 62.6 40.6 35.4 47.2 38.9 65.3 32.0 75.4 84.0 33.2 114.3 39.0 18.8 47.4 31.4 27.8 75.6 28.5 29.4 29.2 29.0 61.9 22.9 23.3 28.3 21.7 37.7 69.7 35.3 40.0 61.4 24.9 25.8 25.3 37.5 29.8 27.6 25.5 26.9 33.8 21.4 119.1 93.9 158.5 221.9 205.7 52.1 151.9 114.7 164.6 121.7 115.1 9.8 396.5 263.6 267.2 515.0 152.3 149.0 93.5 255.0 368.3 172.3 213.0 169.8 170.4 287.4 68.3 140.2 108.6 138.2 238.7 139.8 214.9 126.5 342.7 139.0 49.5 230.5 135.3 138.6 288.5 32.6 148.8 177.5 257.9 168.3 185.9 373.9 156.9 171.4 236.4 PSMA5 ZETA ENSG00000143106 "Proteasome subunit alpha 5" P28066 1 109399031-109426427 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 31.2" "Low region specificity" "Detected in all" "HPA028392, HPA028398, HPA028441" Approved Supported Cytosol NA NA 22000000 Cytosol "HPA028392: AB_10600115, HPA028398: AB_10602310, HPA028441: AB_10602003" "unprognostic (3.82e-2)" "unprognostic (3.09e-3)" "prognostic favorable (1.45e-5)" "unprognostic (1.57e-1)" "unprognostic (2.71e-1)" "unprognostic (1.52e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (5.95e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-3)" "unprognostic (4.20e-3)" "unprognostic (3.05e-1)" "unprognostic (1.07e-3)" "unprognostic (3.99e-2)" "unprognostic (2.34e-1)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" 12.1 23.7 13.2 17.3 15.0 7.7 16.2 8.2 40.5 13.3 16.1 9.8 16.7 15.1 15.8 23.0 21.5 17.6 16.7 20.8 13.8 13.5 27.5 41.9 17.1 24.2 13.4 14.9 13.6 21.4 12.6 11.5 20.9 12.8 12.3 14.9 10.2 16.8 14.2 31.6 15.8 21.8 14.4 12.9 18.5 15.2 16.3 10.3 31.5 27.9 23.4 19.8 14.0 11.7 2.1 1.2 7.3 2.2 2.8 7.1 1.6 1.2 1.0 1.7 1.2 3.9 4.2 1.4 0.9 9.3 6.1 3.6 1.3 1.1 5.3 1.2 4.1 0.4 1.7 2.4 3.1 3.8 1.1 1.5 2.3 0.9 1.6 2.9 3.0 1.2 1.9 3.1 1.8 3.0 1.5 2.3 1.6 1.8 1.4 2.5 1.6 31.2 1.3 1.4 1.3 1.5 0.8 3.1 0.9 4.9 1.6 1.4 1.2 1.6 5.5 2.0 1.4 1.2 2.7 1.5 1.0 0.8 2.1 1.2 0.9 1.8 6.7 6.8 6.7 1.1 7.3 1.0 0.7 4.0 2.2 4.8 1.8 5.8 4.9 1.2 2.1 7.1 6.5 0.3 2.8 2.0 0.8 5.3 1.6 13.2 15.0 8.2 17.5 13.8 13.5 13.4 14.9 12.8 10.3 38.7 52.0 75.2 57.4 56.4 28.9 80.5 71.4 113.8 56.9 40.1 5.9 188.1 119.3 151.2 42.4 54.0 101.9 93.5 159.8 154.0 44.1 63.2 80.8 125.2 151.4 12.7 54.1 53.4 54.0 13.6 62.7 72.3 55.6 215.6 84.3 42.7 167.1 91.2 58.4 151.0 27.9 45.3 54.2 105.7 86.6 57.6 201.7 98.3 114.8 81.6 PSMA6 "IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27" ENSG00000100902 "Proteasome subunit alpha 6" P60900 14 35278633-35317493 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 12 "Late spermatids: 395.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003049 Approved Supported Nucleoplasm NA NA 19000000 Nucleoplasm "HPA003049: AB_1079703" "unprognostic (9.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.90e-2)" "unprognostic (8.07e-2)" "unprognostic (3.42e-2)" "unprognostic (4.11e-3)" "unprognostic (7.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.27e-4)" "unprognostic (1.29e-3)" "unprognostic (2.63e-1)" "unprognostic (1.52e-2)" "unprognostic (2.05e-1)" "unprognostic (5.45e-2)" "unprognostic (3.49e-1)" "unprognostic (5.08e-2)" 33.8 42.7 26.7 31.4 38.8 37.1 38.7 24.2 35.0 28.0 35.8 19.4 24.5 32.2 31.0 30.2 37.9 24.7 20.3 54.2 30.5 27.6 47.3 49.0 37.3 36.4 30.1 36.8 31.1 36.7 14.2 35.8 61.2 31.8 22.5 38.6 18.1 27.3 25.5 94.6 31.8 39.5 27.3 25.2 35.7 28.9 67.5 26.5 86.2 26.0 37.2 38.1 28.8 24.5 37.9 68.5 41.4 65.1 49.9 54.8 104.8 59.7 44.2 33.1 33.6 27.3 29.2 66.2 31.3 38.3 47.4 43.1 41.1 43.3 40.0 60.3 30.4 28.5 42.8 38.6 35.7 56.8 40.2 21.1 31.4 32.2 122.9 31.0 65.3 29.4 22.2 29.7 33.1 42.2 23.6 40.0 68.7 33.5 28.0 38.2 63.3 99.9 55.8 31.6 49.2 50.4 148.9 33.6 32.0 40.5 76.8 35.2 29.8 34.9 51.5 32.9 29.2 61.6 43.3 33.3 30.5 30.2 31.0 34.6 29.9 65.4 73.1 24.8 41.4 34.4 32.8 65.1 41.4 46.3 59.4 46.2 37.9 44.8 47.1 66.8 29.9 35.9 43.0 23.5 49.9 56.6 68.5 54.8 104.8 26.7 38.8 24.2 35.0 30.5 27.6 30.1 36.8 31.8 26.5 41.7 28.9 14.5 10.6 29.7 14.3 1.2 15.3 83.0 59.1 14.0 23.6 27.2 18.3 26.4 121.5 28.7 25.7 23.3 31.8 22.0 14.4 12.4 53.1 20.3 20.7 23.8 17.2 30.7 36.5 395.6 21.0 54.6 23.6 27.1 17.6 8.7 26.5 21.0 16.3 18.9 17.8 12.9 22.1 22.9 17.9 29.0 34.6 29.4 22.2 15.3 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome subunit alpha 7" O14818 20 62136735-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved NA NA 26000000 "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: AB_2680006" "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavorable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 45.1 40.2 26.5 35.0 28.0 56.1 53.1 23.8 30.7 23.2 34.2 21.1 25.4 32.1 33.3 26.6 36.6 26.4 27.3 64.7 26.3 25.7 36.0 63.6 32.8 36.0 28.4 27.0 28.0 48.0 17.1 21.5 27.9 25.0 27.7 27.6 20.7 25.7 27.7 130.5 26.2 33.1 36.9 24.7 34.8 29.7 16.1 22.6 37.2 33.0 53.4 36.8 36.1 44.0 92.3 112.0 124.4 111.2 64.3 114.6 153.5 56.9 70.6 43.6 45.3 40.2 31.0 40.2 44.7 36.6 110.1 46.5 185.0 53.6 47.3 104.2 44.8 71.2 68.4 40.7 79.2 54.9 29.7 31.4 106.1 71.3 93.3 49.9 45.1 62.3 33.0 64.8 56.8 50.6 27.7 54.4 46.3 46.5 45.3 47.7 58.3 72.2 72.1 36.6 63.3 102.3 50.5 82.2 51.3 42.0 53.7 58.7 36.1 67.3 83.6 71.9 29.3 50.1 68.4 44.3 98.0 80.7 51.4 66.4 32.4 49.9 55.7 68.3 34.6 56.9 98.4 111.2 124.4 93.3 109.7 79.2 92.3 93.7 92.0 102.8 83.7 74.7 77.5 94.4 64.3 109.7 112.0 114.6 153.5 26.5 28.0 23.8 30.7 26.3 25.7 28.4 27.0 25.0 22.6 196.5 155.3 252.3 303.7 332.6 126.5 267.8 364.3 245.0 226.3 244.3 68.7 587.8 422.7 492.7 257.1 315.9 330.8 350.4 630.8 671.4 333.0 338.3 242.8 717.4 718.5 77.9 222.6 352.9 445.3 113.3 309.8 460.9 349.2 628.4 200.1 169.6 555.7 259.6 276.2 527.8 96.0 226.4 368.4 74.4 147.9 270.4 713.1 268.8 302.8 319.1 PSMA8 "MGC26605, PSMA7L" ENSG00000154611 "Proteasome subunit alpha 8" Q8TAA3 18 26133852-26193355 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 36.5" "Cell type enriched" "Detected in some" 26 "Spermatocytes: 183.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 80 "Daudi: 23.7;JURKAT: 6.8;U-266/70: 14.7;U-266/84: 15.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "unprognostic (5.39e-3)" "unprognostic (7.45e-5)" "unprognostic (2.94e-1)" "unprognostic (3.04e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-1)" "unprognostic (1.99e-1)" "unprognostic (8.30e-2)" "unprognostic (7.54e-4)" "unprognostic (4.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.56e-1)" 0.1 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 1.1 0.0 36.5 0.2 0.7 0.1 0.0 2.2 0.1 0.0 4.0 1.9 0.2 0.1 1.2 5.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 15.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.1 2.2 4.0 2.1 3.9 0.3 3.1 2.4 5.8 0.2 1.2 0.1 1.9 4.3 1.4 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.2 0.0 0.0 1.5 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 6.3 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 3.6 1.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 6.5 0.0 183.4 7.0 0.0 0.8 0.0 0.0 0.0 PSMB1 "HC5, PMSB1" ENSG00000008018 "Proteasome subunit beta 1" P20618 6 170535117-170553341 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029635, HPA029637, CAB033911" Enhanced Supported Nucleoplasm NA NA 14000000 Nucleoplasm "CAB033911: AB_2268890, HPA029635: AB_10599738, HPA029637: AB_10601793" "unprognostic (2.78e-2)" "unprognostic (3.10e-2)" "unprognostic (6.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (5.41e-3)" "unprognostic (2.36e-2)" "unprognostic (3.32e-2)" "unprognostic (8.39e-2)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (3.63e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-3)" "unprognostic (9.62e-2)" 60.8 59.3 38.5 40.4 53.7 53.2 55.0 31.4 46.4 40.5 48.6 37.9 49.9 45.1 56.8 90.6 51.7 49.8 43.1 71.9 40.9 40.1 56.4 93.2 46.9 66.7 40.8 41.1 43.7 67.3 35.4 48.4 80.6 48.4 40.6 52.7 43.8 43.6 50.0 109.3 56.1 46.0 59.7 44.9 51.4 46.9 47.1 38.1 47.1 47.9 75.2 60.4 50.1 42.0 71.0 98.1 51.9 81.9 71.6 79.3 104.1 43.1 40.6 57.9 74.7 51.8 40.7 61.7 41.3 60.8 69.0 70.5 88.7 37.3 63.2 54.0 55.3 63.5 43.7 64.1 65.7 72.0 64.2 72.2 54.0 41.2 111.2 60.8 63.2 48.1 46.4 40.4 66.5 43.2 47.5 58.8 40.0 106.5 54.3 62.8 116.2 47.3 88.3 52.8 78.8 55.9 45.9 45.9 80.1 71.5 26.0 57.9 47.3 39.7 61.8 31.6 53.9 42.2 91.6 44.7 28.1 45.1 68.3 76.3 46.5 61.4 78.4 65.6 71.7 60.2 40.1 81.9 51.9 53.2 75.8 62.1 71.0 62.2 57.7 98.1 53.4 59.2 57.2 47.5 71.6 67.6 55.8 79.3 104.1 38.5 53.7 31.4 46.4 40.9 40.1 40.8 41.1 48.4 38.1 104.2 145.5 160.9 308.1 192.9 104.7 211.7 249.7 199.4 117.2 134.3 39.3 748.5 339.8 368.1 245.5 214.1 220.2 116.8 565.6 684.7 208.1 230.0 184.8 268.0 350.5 112.8 158.7 149.8 159.1 57.7 237.3 212.8 219.4 422.0 169.6 196.7 419.2 227.4 221.7 419.5 99.6 187.5 291.5 198.6 166.3 188.6 1001.7 194.1 216.2 303.9 PSMB10 "beta2i, LMP10, MECL1, MGC1665" ENSG00000205220 "Proteasome subunit beta 10" P40306 16 67934502-67937087 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 117.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 36.6;U-266/70: 41.0" "HPA030224, HPA030225, CAB034384" Enhanced Approved Vesicles,Cytosol NA NA 1400000 Cytosol Vesicles "CAB034384: AB_2171876, HPA030224: AB_2673382, HPA030225: AB_10603231" "unprognostic (1.18e-2)" "unprognostic (1.90e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-3)" "unprognostic (2.00e-1)" "unprognostic (1.85e-2)" "unprognostic (7.22e-2)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" "unprognostic (2.97e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-2)" "prognostic favorable (5.44e-4)" 11.5 13.0 9.1 24.9 11.8 23.9 11.4 4.0 7.8 8.0 21.6 5.6 8.5 42.4 9.3 9.5 10.6 12.4 16.6 12.0 6.9 4.9 16.9 17.2 19.5 38.3 9.5 5.6 8.7 61.5 0.9 6.9 11.2 8.5 13.5 6.3 5.8 27.9 11.6 6.9 7.0 35.6 7.7 6.5 49.7 23.8 2.5 7.8 39.2 13.1 10.4 20.5 13.2 8.4 50.8 75.2 100.0 98.1 69.1 68.8 117.3 6.0 5.3 0.4 0.8 0.4 3.5 21.3 2.0 8.7 7.0 9.9 2.8 29.5 22.0 3.8 2.7 2.1 8.9 0.1 2.0 0.5 9.7 0.5 7.8 1.8 3.1 12.2 14.5 24.0 5.4 1.2 3.1 0.0 2.2 4.0 5.3 0.7 8.4 2.0 7.5 28.5 14.9 0.3 0.2 2.0 36.6 2.2 30.0 4.8 10.5 0.3 0.4 6.8 12.0 2.6 0.4 2.4 31.5 6.8 4.5 1.2 1.9 2.3 41.0 7.4 14.6 11.1 19.0 9.6 57.1 89.4 67.1 68.8 98.1 50.2 50.8 54.0 57.3 74.6 49.1 45.3 50.1 100.0 69.1 71.4 75.2 60.8 117.3 9.1 11.8 4.0 7.8 6.9 4.9 9.5 5.6 8.5 7.8 20.8 23.2 54.7 11.4 15.2 0.6 1.4 38.2 73.6 15.9 17.4 0.0 24.0 19.9 48.2 11.5 22.9 90.1 23.3 91.6 28.8 24.3 10.7 49.8 10.0 80.6 0.0 15.6 31.3 88.4 25.3 27.9 74.2 45.5 124.4 58.4 1.3 49.6 106.6 19.8 53.7 1.0 19.4 23.4 16.6 6.8 8.7 18.9 122.2 72.8 19.2 PSMB11 beta5t ENSG00000222028 "Proteasome subunit beta 11" A5LHX3 14 23042167-23044276 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 32.7" "Group enriched" "Detected in some" 7 "Early spermatids: 1.3;Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 6 "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 21 "T-cells: 2.1" "Cell line enriched" "Detected in single" 4 "PC-3: 1.8" "Region enriched" "Detected in single" 7 "olfactory region: 2.3" "Not detected" "Not detected" "HPA028967, HPA056970" Enhanced NA NA "HPA028967: AB_2732444, HPA056970: AB_2683293" "unprognostic (7.96e-2)" "unprognostic (2.77e-1)" 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 32.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PSMB2 HC7-I ENSG00000126067 "Proteasome subunit beta 2" P49721 1 35599544-35641844 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026322, HPA026324" Approved Enhanced Nucleoplasm NA NA 15000000 Nucleoplasm "HPA026322: AB_1855821, HPA026324: AB_1855822" "unprognostic (3.54e-2)" "unprognostic (8.53e-2)" "unprognostic (1.63e-3)" "unprognostic (6.93e-2)" "unprognostic (6.41e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.49e-7)" "unprognostic (2.81e-2)" "unprognostic (5.23e-2)" "unprognostic (3.34e-3)" "unprognostic (7.87e-2)" "unprognostic (4.45e-1)" "prognostic unfavorable (2.80e-6)" "unprognostic (1.65e-1)" "unprognostic (2.83e-1)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" 26.5 30.5 29.4 28.0 35.1 37.2 25.3 20.1 50.9 23.2 26.1 35.9 15.4 27.5 27.8 25.0 30.4 26.5 20.7 23.8 30.6 33.4 27.9 63.8 24.6 30.4 30.6 24.8 22.7 24.6 22.0 21.8 37.5 32.6 23.1 27.8 22.8 23.0 24.9 54.7 28.2 27.0 28.7 32.5 29.3 22.8 23.5 21.5 42.8 22.7 29.1 34.0 23.9 22.4 24.6 30.2 19.4 35.3 25.1 28.1 25.4 40.9 25.7 28.1 19.1 14.9 17.9 35.5 19.4 22.9 40.1 32.7 30.4 49.3 40.9 45.7 22.9 24.5 25.5 36.1 32.2 33.8 33.3 33.5 37.1 28.1 29.7 26.9 38.9 21.9 19.5 20.4 47.9 23.2 16.4 31.5 33.9 44.2 23.4 25.8 18.8 50.6 29.1 37.5 18.2 27.4 31.4 28.6 28.8 27.8 22.2 24.9 18.3 22.3 21.1 30.1 33.5 15.5 17.7 21.6 20.1 23.7 18.9 45.9 20.2 32.4 41.5 29.7 41.0 34.8 17.4 27.0 19.4 23.1 33.0 23.4 24.6 23.1 24.2 29.7 19.3 16.7 20.9 9.7 25.1 35.3 30.2 28.1 25.4 29.4 35.1 20.1 50.9 30.6 33.4 30.6 24.8 32.6 21.5 59.6 61.8 70.7 120.5 98.8 48.7 51.8 71.4 68.3 47.8 62.8 15.7 342.2 122.7 240.6 77.0 88.7 69.5 23.3 197.3 290.1 75.1 97.6 33.6 136.0 195.7 55.6 94.4 84.7 99.4 12.8 93.2 93.1 72.6 231.8 76.2 58.8 222.8 74.6 85.9 183.0 36.4 90.5 72.1 168.5 124.8 97.5 369.7 82.8 96.1 159.8 PSMB3 "HC10-II, MGC4147" ENSG00000277791 "Proteasome subunit beta 3" P49720 17 38752736-38764231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 99.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042775, HPA048147" Approved NA NA 28000000 "HPA042775: AB_2678158, HPA048147: AB_2680285" "unprognostic (1.86e-1)" "unprognostic (4.84e-3)" "unprognostic (1.44e-1)" "unprognostic (4.80e-2)" "unprognostic (6.68e-2)" "unprognostic (1.14e-3)" "unprognostic (5.46e-2)" "unprognostic (2.46e-2)" "unprognostic (2.02e-1)" "unprognostic (1.75e-2)" "unprognostic (3.65e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.71e-6)" "unprognostic (4.44e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-3)" "unprognostic (6.03e-2)" 13.3 9.6 5.2 9.9 8.6 13.3 10.3 3.0 13.9 8.5 11.8 7.5 6.4 9.2 5.6 15.3 14.7 10.3 9.8 15.6 4.4 21.6 36.8 11.6 13.0 8.4 7.1 9.6 11.3 7.3 5.7 17.2 8.5 10.8 12.0 9.1 8.5 10.0 22.2 10.0 14.1 11.0 4.7 17.5 7.2 8.5 7.0 23.3 16.7 12.2 15.6 10.2 5.6 32.7 55.0 99.0 56.5 29.1 43.1 63.7 28.1 52.9 22.0 33.9 24.4 19.2 28.1 18.5 31.5 65.2 57.5 63.2 36.6 32.3 33.5 27.7 46.2 48.5 36.3 35.9 40.4 42.2 63.6 20.8 30.7 65.6 12.1 33.2 32.0 20.1 22.1 49.0 16.6 16.8 35.2 38.2 33.4 36.8 31.4 36.8 51.7 51.8 29.7 33.8 39.5 29.2 44.5 50.6 38.0 28.7 27.1 17.9 23.8 18.1 23.0 32.1 41.5 38.7 18.5 17.1 31.6 36.3 47.3 24.1 40.8 41.9 33.9 32.9 30.0 41.1 56.5 47.4 30.3 49.7 27.9 32.7 28.5 27.6 55.0 28.1 23.0 24.8 99.0 29.1 39.9 53.2 43.1 63.7 71.5 124.7 150.3 148.2 177.2 62.4 281.8 122.3 170.0 120.6 167.5 23.6 383.7 344.8 286.9 26.5 168.4 172.3 93.5 430.9 364.8 178.3 175.3 150.1 236.3 368.1 28.6 128.1 114.8 177.4 35.0 138.4 256.1 190.6 331.0 131.4 145.3 327.0 210.5 137.2 493.2 50.1 122.9 183.6 147.5 74.1 176.0 421.6 159.6 160.1 208.1 PSMB4 "HN3, PROS26" ENSG00000159377 "Proteasome subunit beta 4" P28070 1 151399534-151401944 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006700, HPA073499" Approved Supported Nucleoplasm,Mitochondria NA NA 15000000 Nucleoplasm Mitochondria "HPA006700: AB_1079704, HPA073499: " "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (2.69e-1)" "unprognostic (2.52e-1)" "unprognostic (1.63e-1)" "unprognostic (5.74e-2)" "prognostic unfavorable (7.45e-4)" "unprognostic (2.27e-1)" "unprognostic (1.69e-1)" "unprognostic (4.37e-3)" "unprognostic (3.73e-1)" "unprognostic (3.77e-1)" "prognostic unfavorable (2.90e-10)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (3.82e-2)" "unprognostic (5.85e-2)" 45.7 64.5 47.4 40.4 49.5 40.2 56.3 39.6 84.0 44.4 44.3 28.5 58.8 41.2 53.5 65.3 55.7 51.2 37.8 66.6 47.0 50.7 57.3 71.9 43.6 81.1 49.2 61.0 52.4 87.0 40.0 45.4 50.9 48.4 42.6 47.5 37.8 46.7 56.1 68.7 45.7 39.7 66.4 55.1 46.6 43.4 31.8 36.3 51.1 46.8 63.3 62.2 58.6 37.7 68.5 106.5 58.6 81.4 72.5 89.0 78.3 52.1 54.7 46.6 55.8 52.8 50.4 64.1 30.8 67.2 89.9 63.1 73.2 70.5 47.5 93.4 51.5 47.8 52.4 47.3 57.9 51.3 66.2 47.8 32.8 41.0 54.7 57.1 45.7 45.2 55.0 55.4 84.4 34.7 45.8 62.7 51.3 53.0 93.0 63.3 139.7 54.8 53.9 119.2 77.4 71.0 52.6 34.1 83.8 73.4 42.7 51.8 61.5 35.8 78.3 103.0 60.3 70.7 72.5 39.7 39.5 42.1 41.9 67.6 92.7 106.1 91.6 58.3 40.7 83.0 54.6 81.4 49.5 63.9 75.2 75.9 68.5 74.9 72.5 96.4 60.8 65.8 68.0 58.6 72.5 56.9 106.5 89.0 78.3 47.4 49.5 39.6 84.0 47.0 50.7 49.2 61.0 48.4 36.3 142.9 125.8 60.3 65.1 68.1 51.9 108.2 81.5 179.3 134.2 68.0 15.7 176.7 87.9 106.1 12.6 85.2 80.0 46.7 168.6 123.7 82.9 62.0 103.4 133.7 108.0 46.1 63.8 90.9 107.2 13.4 96.7 88.1 91.1 226.4 73.7 84.2 122.6 66.6 99.0 122.6 44.8 64.7 80.2 38.6 45.3 66.4 223.6 74.3 80.9 77.2 PSMB5 "MB1, X" ENSG00000100804 "Proteasome subunit beta 5" P28074 14 23016543-23035230 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049518, HPA061796" Approved Supported Nucleoplasm,Centrosome NA NA 8200000 "Nucleoplasm, Centrosome" "HPA049518: AB_2680802, HPA061796: AB_2684612" "unprognostic (3.03e-1)" "unprognostic (1.99e-2)" "unprognostic (8.35e-2)" "unprognostic (6.13e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.85e-4)" "prognostic unfavorable (2.90e-5)" "unprognostic (2.55e-2)" "unprognostic (9.95e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.19e-1)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.95e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (4.73e-4)" 28.1 38.8 33.6 19.3 35.5 9.6 29.0 19.4 42.9 24.7 28.3 26.8 25.4 21.0 24.2 49.2 31.6 31.6 22.0 37.7 32.9 33.3 35.3 45.4 20.6 18.3 37.5 35.4 22.2 36.6 35.4 26.6 32.5 33.9 27.2 32.2 21.1 28.4 28.7 101.2 22.3 17.2 34.9 32.5 16.7 25.1 27.6 27.3 15.7 29.0 47.3 22.7 20.6 25.2 32.3 53.4 24.6 39.9 19.4 46.8 39.5 22.5 48.1 34.4 32.6 46.4 40.1 34.0 32.2 38.4 56.9 48.4 40.5 36.0 28.0 30.1 43.8 39.5 30.8 54.9 40.2 55.0 17.2 37.9 17.8 35.1 142.5 36.6 21.6 21.4 44.7 37.7 42.2 35.2 37.8 58.8 24.7 26.7 16.0 46.5 66.5 12.3 29.6 38.2 43.6 78.0 16.6 26.0 18.7 44.2 32.7 43.9 34.2 22.7 46.1 31.0 47.0 22.2 28.1 31.6 27.9 28.4 25.8 31.6 13.8 27.3 21.0 21.8 17.4 34.5 24.6 39.9 17.3 29.3 39.0 34.2 32.3 35.1 28.1 42.6 30.1 46.8 35.6 15.5 19.4 27.9 53.4 28.7 39.5 33.6 35.5 19.4 42.9 32.9 33.3 37.5 35.4 33.9 27.3 71.5 50.9 58.0 134.8 124.6 57.4 134.8 129.9 149.9 80.8 90.7 27.5 350.9 233.8 261.5 57.3 106.7 63.2 0.0 201.1 383.6 136.2 130.9 30.1 134.4 190.5 66.7 148.5 90.9 54.9 77.1 109.9 70.7 109.6 199.2 94.1 137.0 244.2 80.7 114.9 331.7 53.8 97.0 134.4 207.4 76.8 137.3 359.7 49.8 123.0 163.4 PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome subunit beta 6" P28072 17 4796144-4798503 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Cytosol NA NA 2800000 Nucleoplasm Cytosol "HPA023312: AB_1855828, HPA063656: AB_2685078" "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (3.32e-3)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-2)" "unprognostic (7.47e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (5.27e-2)" "unprognostic (5.66e-2)" 28.6 35.0 33.7 23.2 36.4 31.7 34.0 24.2 41.5 29.6 31.7 26.7 26.8 22.6 33.4 47.1 41.9 30.3 24.2 72.0 30.4 30.5 41.4 67.1 25.7 35.3 33.4 34.0 25.3 41.8 40.8 26.6 49.6 35.9 26.4 36.1 23.5 30.6 36.6 97.4 33.6 23.2 40.5 29.7 29.0 31.2 27.0 28.0 35.8 34.6 53.8 39.6 27.9 26.0 93.9 96.3 51.1 95.3 60.4 81.2 107.9 46.8 82.1 44.3 37.8 37.8 34.0 51.1 24.9 52.1 76.0 59.7 61.0 38.3 36.5 49.4 59.5 43.8 47.6 67.3 69.6 74.2 47.4 71.0 21.6 54.0 70.8 43.6 22.3 34.5 32.0 53.5 66.4 63.2 42.9 73.8 58.3 33.0 55.5 58.2 55.8 39.4 37.3 37.5 60.6 57.0 44.2 31.5 48.3 57.1 31.6 25.9 31.8 35.7 27.9 25.6 48.4 34.0 25.1 35.2 37.5 28.4 50.4 60.1 23.2 30.9 22.2 53.7 40.8 45.1 51.1 95.3 50.5 57.1 87.5 57.8 93.9 62.3 62.6 96.3 79.8 53.7 56.1 32.9 60.4 78.0 89.7 81.2 107.9 33.7 36.4 24.2 41.5 30.4 30.5 33.4 34.0 35.9 28.0 125.0 90.0 86.3 149.5 203.5 62.3 388.1 150.3 148.5 136.5 127.4 15.7 501.8 303.4 283.2 179.9 152.8 127.2 46.7 303.5 339.8 176.1 166.1 102.7 181.7 306.8 30.2 142.4 94.5 116.6 27.7 101.5 205.7 224.4 422.0 103.5 128.7 291.3 143.8 115.6 455.7 57.6 109.9 242.8 120.2 84.7 242.3 555.7 109.0 129.8 191.2 PSMB7 ENSG00000136930 "Proteasome subunit beta 7" Q99436 9 124353466-124415444 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052408, HPA054902" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No No 2700000 Nucleoplasm "Nuclear bodies, Cytosol" "HPA052408: AB_2681820, HPA054902: AB_2682635" "unprognostic (7.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (3.64e-3)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.24e-3)" "unprognostic (9.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.67e-1)" "unprognostic (3.45e-1)" "unprognostic (1.93e-3)" "unprognostic (3.98e-2)" 36.9 56.9 51.0 32.8 55.1 53.4 41.9 33.7 52.7 26.6 33.3 34.0 27.9 32.5 33.6 52.1 41.9 32.6 29.2 59.6 44.5 41.3 53.7 87.1 27.0 33.6 43.6 46.9 32.7 67.1 38.5 24.1 53.2 47.3 28.8 37.1 31.1 48.2 26.9 76.7 48.7 32.2 31.4 39.9 28.6 33.1 50.3 36.5 48.2 32.7 67.7 39.5 32.3 30.8 53.4 67.9 45.2 62.7 53.6 66.2 69.0 52.6 64.4 44.1 53.3 31.2 37.2 63.6 51.3 70.8 74.4 51.4 84.6 51.6 60.1 41.5 48.0 73.5 75.4 54.9 54.3 68.4 57.8 47.4 37.7 102.4 70.2 70.5 74.7 37.6 44.5 48.0 77.5 77.7 57.5 62.4 54.6 76.8 42.8 57.4 91.7 53.5 50.2 65.2 80.2 92.2 47.4 65.8 70.2 52.6 34.5 52.1 42.3 48.8 62.5 76.0 45.2 72.1 32.9 49.4 48.2 38.9 61.4 76.8 46.5 130.1 60.7 80.6 46.1 67.6 40.4 61.7 45.2 41.8 62.7 45.0 53.4 48.1 46.1 67.9 47.5 46.3 44.9 27.3 53.6 58.4 57.8 66.2 69.0 51.0 55.1 33.7 52.7 44.5 41.3 43.6 46.9 47.3 36.5 71.5 73.0 111.6 140.8 172.4 37.7 121.6 112.1 101.7 62.6 66.3 21.6 382.0 280.2 281.6 279.3 121.5 147.6 46.7 340.4 299.5 140.7 127.9 102.7 222.4 205.6 31.8 135.5 87.8 123.1 322.3 128.9 128.4 189.0 172.3 121.7 86.0 308.8 129.0 117.8 341.8 43.4 84.1 126.0 246.2 184.2 191.3 408.7 106.6 146.6 177.4 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome subunit beta 8" P28062 6 32840717-32844703 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" No No 3300000 Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 17.0 21.9 7.9 34.8 11.7 14.0 14.9 3.6 7.5 10.0 20.8 5.1 8.8 20.1 12.5 15.3 16.6 13.2 23.8 10.6 6.6 5.7 20.9 30.0 29.0 46.3 9.9 5.1 11.3 12.7 3.6 8.2 9.7 8.8 13.5 24.4 9.2 14.6 11.2 5.1 14.7 37.3 11.5 9.0 42.8 19.4 3.9 9.0 32.2 18.7 18.7 29.0 13.9 12.5 28.9 27.4 37.6 33.2 23.3 29.9 52.2 6.4 2.0 0.1 0.0 2.7 7.1 4.4 1.5 10.2 12.5 18.1 0.0 11.4 25.1 4.8 4.1 9.8 4.5 1.4 6.1 3.4 10.3 0.0 11.1 1.3 0.4 15.0 0.2 4.2 8.0 2.8 7.0 2.4 0.4 8.4 5.4 0.3 5.3 3.1 0.0 5.8 6.1 0.0 0.0 1.6 15.6 0.8 12.4 10.2 1.8 0.1 0.1 2.2 5.4 3.4 0.0 2.4 20.5 2.5 3.7 2.0 3.5 0.2 8.9 8.4 5.6 1.3 14.5 4.7 19.4 29.0 37.4 25.5 33.2 22.1 28.9 21.7 26.4 27.4 26.3 15.1 21.6 37.6 23.3 28.6 23.3 29.9 52.2 7.9 11.7 3.6 7.5 6.6 5.7 9.9 5.1 8.8 9.0 35.7 58.8 174.3 61.0 75.0 1.6 6.1 79.0 62.9 45.5 59.3 0.0 1.7 72.9 173.5 0.5 121.7 242.4 0.0 217.6 10.1 57.2 72.3 49.7 67.1 157.1 6.4 63.1 92.1 135.9 0.6 36.2 111.9 54.0 193.0 164.1 32.8 163.9 247.6 28.7 51.6 2.7 38.8 45.7 0.2 1.2 69.5 2.3 193.7 184.0 98.2 PSMB9 "beta1i, LMP2, PSMB6i, RING12" ENSG00000240065 "Proteasome subunit beta 9" P28065 6 32844136-32859585 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 69.1;lymphoid tissue: 54.9" "Cell type enhanced" "Detected in many" 6 "monocytes: 319.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 29.5;REH: 21.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB015180, HPA042818, HPA053280" Enhanced Supported Cytosol NA NA 420000 Cytosol "CAB015180: AB_2172368, HPA042818: AB_2678186, HPA053280: AB_2682098" "unprognostic (1.09e-2)" "unprognostic (1.68e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-3)" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (5.68e-2)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (6.50e-3)" "unprognostic (1.87e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.96e-3)" "unprognostic (5.99e-2)" 13.3 9.7 5.0 30.0 7.9 10.7 11.6 1.6 5.3 7.6 16.5 6.0 3.4 15.7 8.8 7.1 10.8 7.4 10.8 8.9 5.1 4.7 12.2 12.2 17.7 32.7 7.3 3.7 9.2 5.4 1.2 4.5 5.5 6.3 12.5 5.8 7.7 9.0 3.5 6.2 7.6 36.1 5.7 9.8 54.9 11.2 3.0 6.7 35.4 14.4 9.3 35.2 15.9 8.8 31.8 17.2 69.1 30.5 23.4 31.1 45.7 0.0 1.4 0.0 0.1 1.2 3.0 2.0 0.2 3.3 4.2 9.9 0.0 9.2 29.5 0.4 2.7 10.8 6.0 0.4 6.3 0.6 16.6 0.0 18.0 0.5 1.1 15.9 3.1 1.3 1.4 0.2 2.7 0.4 2.3 1.5 8.5 0.7 5.5 1.4 0.5 13.6 4.2 0.0 0.0 0.9 21.8 0.0 7.0 2.8 0.5 0.0 0.0 2.7 1.8 2.0 0.0 2.4 6.6 1.5 4.6 0.4 8.6 2.6 10.2 15.5 9.4 4.7 11.9 3.8 21.9 22.4 39.3 28.7 30.5 23.8 31.8 23.3 27.5 17.2 23.4 17.5 22.9 69.1 23.4 29.4 12.7 31.1 45.7 5.0 7.9 1.6 5.3 5.1 4.7 7.3 3.7 6.3 6.7 38.7 64.6 199.7 29.6 64.5 1.9 5.3 73.9 30.8 34.2 24.4 0.0 0.9 16.6 87.6 1.0 123.4 127.8 46.7 101.9 4.2 38.3 33.2 76.1 23.2 118.3 0.0 32.1 108.1 113.4 0.7 27.0 117.7 33.7 319.2 103.0 19.5 69.2 118.1 14.9 33.5 1.1 32.3 41.0 1.4 6.5 51.3 1.1 214.2 55.9 33.0 PSPH PSP ENSG00000146733 "Phosphoserine phosphatase" P78330 7 56011051-56051604 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Distal tubular cells: 91.2;Early spermatids: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020376, HPA029515" Approved Approved Cytosol NA NA Cytosol "HPA020376: AB_1855867, HPA029515: AB_10601492" "prognostic unfavorable (2.30e-4)" "unprognostic (7.80e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (2.75e-5)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (4.45e-2)" "prognostic favorable (3.77e-4)" "unprognostic (3.78e-2)" "unprognostic (5.74e-2)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.90e-3)" "unprognostic (9.05e-3)" 7.5 13.4 14.1 5.9 16.6 5.1 11.0 10.1 14.6 5.4 8.0 13.2 11.4 6.9 7.0 9.0 11.0 26.3 10.6 12.8 13.2 12.5 14.7 9.8 5.4 7.4 14.8 10.0 13.9 15.9 7.8 17.1 6.4 11.1 10.6 6.9 6.9 6.8 11.5 6.8 6.4 6.2 8.5 15.2 5.7 8.5 9.1 13.3 10.2 12.2 6.9 8.5 7.1 16.0 7.8 11.9 6.8 8.5 5.3 6.2 5.8 46.9 14.4 8.8 32.9 7.4 10.0 6.1 11.9 7.0 6.6 11.8 12.9 8.2 23.2 8.0 11.0 16.7 9.8 19.5 10.1 6.9 17.6 10.9 6.5 3.9 21.7 15.9 6.5 10.0 12.5 19.0 10.5 12.2 9.4 6.5 22.0 15.5 15.0 10.0 6.3 9.9 15.5 14.1 16.8 20.2 13.0 5.3 13.3 6.3 2.4 16.1 18.6 8.6 5.3 23.8 7.5 15.9 13.7 5.5 5.8 9.2 17.9 10.8 10.4 18.0 26.3 8.3 14.3 18.2 2.2 7.7 6.8 4.2 5.3 3.0 7.2 4.0 5.1 11.9 7.8 6.2 5.5 3.6 5.3 8.5 11.3 5.1 5.8 14.1 16.6 10.1 14.6 13.2 12.5 14.8 10.0 11.1 13.3 3.0 1.0 9.7 8.3 6.1 4.4 9.4 17.8 34.8 9.1 5.2 2.0 11.9 91.2 7.9 131.4 3.6 1.3 0.0 6.8 6.3 5.3 5.3 1.1 7.3 7.9 1.6 4.6 6.7 6.5 38.2 7.8 4.8 6.8 4.6 3.9 41.4 7.8 3.5 5.6 39.1 2.8 12.9 5.7 23.6 26.0 7.4 3.9 5.0 7.5 4.7 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" NA NA Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.2 4.8 5.5 5.0 12.8 8.8 5.0 5.5 12.2 6.5 9.1 4.9 12.6 12.1 3.7 9.0 3.8 6.2 7.4 6.3 10.3 6.0 2.1 4.0 12.5 6.0 13.7 13.5 6.9 6.0 17.6 8.2 10.6 27.6 9.1 7.7 3.0 32.9 5.9 7.8 7.6 24.6 2.0 8.9 0.0 11.8 2.9 8.9 10.1 5.8 2.0 9.0 7.3 3.5 9.2 4.6 9.7 19.6 7.9 21.4 5.0 8.3 4.4 10.8 14.0 13.8 6.6 12.8 1.2 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 32.8 55.3 40.2 50.0 49.8 113.3 39.2 40.8 25.4 28.4 27.9 37.3 22.6 28.2 23.2 57.0 44.4 33.9 0.0 25.8 44.5 52.3 36.9 25.3 58.6 31.3 42.9 30.0 47.9 167.4 70.7 52.6 69.1 59.1 27.9 44.1 54.1 30.2 24.6 51.2 30.8 55.8 90.5 118.8 24.9 24.0 52.6 47.9 35.7 39.2 51.2 PTP4A1 "PRL-1, PRL1, PTPCAAX1" ENSG00000112245 "Protein tyrosine phosphatase type IVA, member 1" Q93096 6 63521748-63583587 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 135.1;skeletal muscle: 111.2" "Cell type enhanced" "Detected in many" 14 "Late spermatids: 2420.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Approved NA NA "HPA003281: AB_1855903" "unprognostic (8.63e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (9.05e-2)" "unprognostic (7.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.96e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.23e-2)" "unprognostic (1.07e-2)" "unprognostic (6.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (1.11e-2)" 13.9 42.3 11.3 10.5 14.0 54.3 10.8 7.1 17.0 17.5 30.2 18.9 8.0 17.9 13.1 13.5 16.1 12.3 16.7 10.0 12.0 14.8 14.2 135.1 25.0 9.0 16.1 13.8 24.1 87.4 5.0 12.8 19.8 16.3 17.7 31.2 13.6 20.1 10.0 111.2 17.2 18.3 35.7 24.2 7.1 15.5 19.8 13.3 6.4 11.4 19.9 9.3 31.0 12.6 14.6 18.2 46.9 20.6 15.8 20.1 14.4 19.3 24.0 30.3 29.2 20.7 19.2 60.6 34.1 22.8 12.4 17.4 20.2 11.4 16.5 14.8 20.1 25.8 9.6 20.6 42.8 20.0 17.8 13.9 10.3 67.2 91.7 41.0 31.6 16.9 23.4 83.1 26.9 71.9 15.2 19.2 15.7 23.5 32.1 34.5 26.2 15.1 14.2 12.5 21.7 13.1 20.2 12.6 13.1 27.7 23.0 11.4 21.1 74.4 16.3 33.6 36.3 15.7 28.1 19.1 31.3 34.4 24.7 33.5 26.9 23.0 30.5 16.7 16.9 36.7 34.6 19.8 15.2 13.7 20.6 20.1 14.6 15.0 14.6 18.2 12.4 14.8 14.2 46.9 15.8 14.2 9.1 18.1 14.4 11.3 14.0 7.1 17.0 12.0 14.8 16.1 13.8 16.3 13.3 20.8 83.0 74.7 257.9 605.1 22.1 73.9 163.1 38.8 51.2 71.5 15.7 216.2 68.0 128.0 616.2 31.2 259.4 0.0 168.0 175.7 85.2 143.0 64.4 416.3 88.4 11.1 124.3 41.1 65.9 2420.5 26.4 64.7 161.9 36.1 129.4 17.8 159.8 140.8 22.6 85.2 23.2 6.5 110.2 32.8 21.3 560.3 384.3 37.0 97.1 110.7 PTP4A2 "HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, PTP4A, PTPCAAX2" ENSG00000184007 "Protein tyrosine phosphatase type IVA, member 2" Q12974 1 31906421-31944856 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Urothelial cells: 819.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003281, CAB011204" Uncertain NA NA 440000 "CAB011204: AB_532271, HPA003281: AB_1855903" "unprognostic (2.67e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-3)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (6.20e-2)" "prognostic unfavorable (2.62e-5)" "unprognostic (6.90e-2)" "unprognostic (4.63e-2)" "unprognostic (5.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.10e-11)" "unprognostic (1.16e-2)" "unprognostic (3.81e-1)" "unprognostic (2.89e-1)" "prognostic favorable (2.72e-5)" 51.6 22.4 41.1 39.6 57.3 74.6 48.8 12.0 34.6 26.3 37.1 68.9 24.9 31.9 23.4 20.8 25.3 23.9 31.6 64.8 50.6 31.4 26.7 36.3 34.6 44.0 56.3 29.5 34.6 28.5 17.1 19.2 25.8 40.9 28.6 36.9 21.1 28.0 27.5 82.8 16.5 29.1 32.7 58.5 40.9 31.3 44.6 48.7 110.5 48.0 20.0 47.2 49.0 40.3 14.7 14.8 50.0 44.6 18.2 29.0 18.2 42.3 24.7 24.2 45.2 48.6 52.1 16.6 41.6 58.1 34.2 35.6 21.7 61.4 75.3 32.8 56.5 38.5 17.3 24.7 24.2 63.5 67.7 14.0 52.3 43.8 22.5 52.2 42.4 53.0 47.8 20.2 48.2 47.6 34.2 34.6 60.6 67.2 30.9 43.8 20.6 135.8 20.8 32.4 32.5 36.1 23.6 40.7 31.3 22.9 78.4 23.8 17.1 44.3 28.9 47.1 44.1 82.5 23.5 35.7 40.3 34.0 60.0 45.8 32.2 50.2 38.4 39.0 34.8 39.1 50.0 17.2 27.4 25.4 32.6 20.3 14.7 22.6 29.0 14.8 11.3 14.5 24.9 18.0 18.2 44.6 10.7 17.8 18.2 41.1 57.3 12.0 34.6 50.6 31.4 56.3 29.5 40.9 48.7 113.2 107.0 105.7 413.0 172.4 53.2 156.4 145.2 36.1 85.3 191.9 56.9 42.6 162.5 131.4 33.4 86.3 153.7 46.7 159.0 99.5 130.0 535.6 85.4 139.5 112.1 93.8 123.2 81.0 165.5 29.0 163.7 193.7 109.6 162.3 177.6 142.6 155.3 178.2 164.8 128.3 51.1 129.4 116.1 95.6 88.0 171.8 133.9 143.0 162.7 819.0 PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase type IVA, member 3" O75365 8 141391993-141432454 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 166.4" "Cell type enhanced" "Detected in many" 10 "Cardiomyocytes: 234.6;Cone photoreceptor cells: 115.8;Rod photoreceptor cells: 210.7;Smooth muscle cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 30.3;non-classical monocyte: 27.8" "Group enriched" "Detected in many" 7 "granulocytes: 30.3;monocytes: 27.8" "Cell line enhanced" "Detected in some" "HDLM-2: 70.2;Karpas-707: 21.4;REH: 12.0;RPMI-8226: 22.0;U-266/84: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003281 Uncertain NA NA "HPA003281: AB_1855903" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" "unprognostic (5.73e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.81e-5)" "unprognostic (2.25e-1)" "unprognostic (1.12e-2)" "unprognostic (2.28e-2)" "unprognostic (1.77e-1)" 5.9 2.4 2.8 3.9 6.5 1.7 4.1 3.9 10.9 5.5 6.2 2.6 2.5 3.4 7.6 5.4 5.5 6.1 3.0 48.0 2.7 3.0 5.1 1.7 5.5 7.9 2.8 5.0 4.8 13.6 2.4 22.0 4.1 4.6 7.2 2.0 15.7 8.2 3.8 166.4 3.4 3.3 7.6 1.5 5.6 9.9 3.5 0.6 1.7 3.3 15.9 5.1 5.5 3.3 2.8 4.3 30.3 27.8 0.8 3.5 2.5 0.1 0.5 0.8 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.0 0.0 6.5 0.1 0.0 0.0 0.1 0.0 0.0 70.2 0.5 5.0 0.0 1.1 0.5 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.6 2.7 21.4 0.0 5.4 0.6 0.1 1.3 0.5 0.3 12.0 0.0 22.0 0.0 0.1 9.0 2.1 0.4 0.0 1.8 0.6 1.0 0.3 0.1 0.0 1.3 0.0 0.0 6.7 23.3 0.2 0.0 2.0 0.2 0.4 1.6 6.6 1.6 14.8 1.1 2.8 3.5 1.6 1.2 0.8 3.4 1.9 30.3 0.8 27.8 4.3 2.5 2.5 2.8 6.5 3.9 10.9 2.7 3.0 2.8 5.0 4.6 0.6 3.0 45.2 18.2 3.6 8.9 90.4 234.6 5.1 0.0 5.7 7.0 115.8 0.2 8.3 6.5 9.8 29.7 0.0 0.0 53.0 0.2 11.8 9.7 1.1 0.2 3.2 14.3 9.8 9.2 2.8 3.6 3.4 6.0 20.3 10.8 2.4 25.7 16.3 0.0 1.8 4.2 210.7 32.3 93.8 1.8 22.8 8.9 0.2 8.7 2.3 2.5 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase, mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Late spermatids: 522.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 24.0 24.5 22.3 13.1 23.2 19.8 23.3 16.5 25.2 15.7 14.8 18.5 17.5 14.6 14.7 21.4 14.3 16.9 17.9 17.1 18.5 21.9 20.1 21.8 25.1 16.7 23.1 16.2 15.7 39.3 18.3 18.7 21.8 14.4 15.8 11.5 20.1 26.4 19.5 23.4 11.2 13.1 12.7 17.6 14.7 16.9 44.6 10.3 10.8 19.9 15.7 15.0 11.0 11.5 20.4 40.8 22.1 24.4 15.4 17.5 16.8 22.2 12.6 1.5 10.1 11.7 9.0 4.3 13.1 12.4 13.1 12.5 20.9 11.9 16.0 14.5 9.8 12.2 19.1 10.4 13.6 14.0 19.5 31.3 7.4 25.8 26.3 17.2 14.3 9.8 8.9 15.5 6.1 18.8 10.1 9.3 15.9 18.8 12.3 9.6 42.0 12.2 18.5 9.4 3.8 23.4 22.4 8.5 13.7 15.8 14.3 9.4 11.5 19.9 7.3 11.8 6.6 33.8 15.4 10.0 9.7 15.0 15.7 19.7 18.7 12.5 10.9 7.6 12.4 5.9 6.0 24.4 22.1 16.0 20.9 15.4 20.4 15.2 17.3 27.7 18.0 15.2 14.4 1.9 15.4 19.4 40.8 17.5 16.8 22.3 23.2 16.5 25.2 18.5 21.9 23.1 16.2 14.4 10.3 20.8 25.4 25.3 13.5 15.9 13.5 5.3 48.4 41.5 22.7 38.4 3.9 63.4 61.3 87.9 188.7 19.1 21.4 0.0 74.6 54.2 24.4 20.5 16.2 36.5 56.1 4.8 30.1 30.1 29.8 522.3 43.1 32.4 43.9 60.5 41.0 48.4 92.6 28.1 43.9 62.0 11.6 19.4 21.2 109.7 21.3 15.2 64.2 24.9 61.2 18.6 PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase, non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 211.4;monocytes: 327.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Enhanced "Endoplasmic reticulum" NA NA 11000 "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" 22.1 22.2 12.1 31.9 16.0 35.3 17.9 12.9 16.6 18.2 17.8 18.8 14.2 10.5 20.0 16.6 23.2 17.1 18.0 20.5 15.8 9.0 43.8 16.7 42.7 36.1 14.1 14.1 21.8 12.2 31.2 18.8 28.3 18.7 20.0 14.8 21.0 16.3 15.0 41.0 18.6 21.9 16.9 15.8 45.3 17.5 23.5 13.3 26.9 15.7 13.9 42.8 20.0 18.4 15.9 9.4 18.8 16.4 3.9 10.7 6.4 21.1 10.7 12.9 8.9 8.5 11.7 18.4 14.2 13.6 41.9 15.3 31.3 44.6 10.5 25.3 13.1 16.5 18.8 10.2 40.9 26.7 15.5 9.1 14.8 10.4 16.5 16.9 15.4 20.4 13.6 28.7 18.9 23.3 18.4 24.0 12.8 25.8 9.7 22.7 11.8 16.5 12.2 6.8 11.7 14.7 14.7 15.0 10.0 24.1 15.9 10.4 11.9 20.4 26.0 23.0 11.3 16.8 16.5 35.6 36.6 14.7 16.4 17.6 10.6 8.5 12.8 22.9 10.5 13.5 12.0 5.6 18.8 10.7 9.5 7.9 15.9 9.0 8.2 5.5 13.7 7.7 8.3 12.2 3.9 16.4 9.4 7.1 6.4 12.1 16.0 12.9 16.6 15.8 9.0 14.1 14.1 18.7 13.3 211.4 72.3 67.9 44.4 76.4 23.0 27.2 10.2 32.1 47.8 34.9 45.2 41.8 19.9 20.5 47.2 26.1 20.4 0.0 16.9 17.3 21.4 26.7 67.2 18.6 32.9 41.3 17.9 37.4 28.2 22.4 13.0 52.2 35.4 327.4 13.7 13.8 28.9 11.5 11.3 59.6 25.9 19.4 34.0 20.7 24.3 41.3 45.4 43.7 15.5 55.1 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase, non-receptor type 11" Q06124 12 112418351-112509913 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cardiomyocytes: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 160000 "Nucleoli rim" "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 25.4 16.8 38.6 14.4 39.0 17.7 30.8 17.5 39.5 18.3 14.7 26.9 9.9 11.9 19.1 13.3 17.6 11.1 13.1 30.1 38.0 32.2 18.0 23.1 15.1 14.5 45.3 22.5 13.1 14.0 29.3 12.9 16.6 26.2 16.2 13.9 9.4 12.0 20.0 34.0 14.1 11.1 28.0 45.7 10.9 12.8 7.6 32.1 10.9 21.2 8.2 13.7 17.4 15.4 17.3 17.1 22.0 11.8 11.3 15.4 6.3 35.4 33.8 24.7 23.4 36.0 35.2 29.2 43.1 47.0 34.0 25.6 33.7 13.7 37.5 22.5 39.8 21.5 21.2 31.7 38.2 56.5 28.4 26.1 54.5 31.5 18.4 35.9 43.7 34.8 28.4 38.5 36.5 51.9 32.8 28.0 29.0 41.4 13.2 32.8 25.6 30.7 21.3 29.9 34.7 22.2 31.6 36.4 21.5 31.3 39.9 17.2 21.1 41.5 31.8 26.5 26.1 36.6 30.3 34.1 40.0 35.9 23.7 37.6 25.6 42.2 37.5 33.3 30.7 37.3 22.0 11.0 15.0 14.8 9.5 14.1 15.5 13.4 12.1 12.6 17.3 15.4 11.8 10.3 11.3 11.8 17.1 9.8 6.3 38.6 39.0 17.5 39.5 38.0 32.2 45.3 22.5 26.2 32.1 56.6 53.2 13.4 22.8 22.8 27.6 136.3 30.6 20.1 50.0 34.9 15.7 20.0 28.2 34.0 65.9 35.8 17.2 0.0 36.7 21.0 25.9 57.9 26.7 93.6 22.8 12.7 12.6 27.0 32.4 19.0 47.8 23.7 13.5 16.2 19.6 59.0 45.4 20.4 75.0 29.8 21.4 32.3 31.9 7.7 5.3 24.0 29.4 19.8 18.7 65.6 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase, non-receptor type 12" Q05209 7 77537275-77640071 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 1100000 "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 29.6 15.1 14.3 20.5 19.6 29.7 25.1 15.7 22.7 20.0 28.9 8.1 13.8 8.8 20.7 9.6 22.0 18.1 19.8 45.6 17.3 12.6 16.9 14.8 34.7 17.4 15.3 13.4 19.0 10.7 12.4 19.8 36.0 18.6 14.1 13.8 9.9 12.8 17.1 17.6 17.6 14.6 23.0 24.0 25.0 14.4 13.9 17.7 9.7 16.7 11.9 12.9 23.2 61.2 2.5 3.9 9.9 4.9 12.8 3.8 2.8 17.2 10.6 25.2 12.8 17.7 18.5 13.5 18.0 23.0 14.2 20.3 5.2 27.0 2.0 5.8 21.0 31.1 12.3 8.4 18.0 28.7 5.0 4.7 10.8 10.7 21.2 17.4 6.1 7.2 15.1 20.1 30.9 39.9 25.5 30.0 0.5 12.9 3.0 45.2 11.8 0.8 17.1 20.3 23.5 12.2 3.6 20.2 1.0 24.4 9.3 3.1 16.7 22.1 20.3 17.5 45.3 9.8 22.5 21.8 30.8 18.6 11.2 33.9 3.1 1.7 5.3 18.1 15.9 53.3 3.7 4.2 6.6 3.6 2.9 1.4 2.5 1.2 2.7 3.9 1.1 0.6 3.8 9.9 12.8 4.9 0.3 1.5 2.8 14.3 19.6 15.7 22.7 17.3 12.6 15.3 13.4 18.6 17.7 65.5 54.6 13.7 41.5 61.1 15.5 35.1 22.9 16.0 46.6 19.2 7.9 34.1 3.3 38.7 2.6 99.1 17.1 0.0 34.2 48.2 53.7 44.4 13.9 19.2 45.4 33.4 11.6 98.8 74.4 5.4 43.1 86.9 33.7 25.2 19.9 63.0 55.1 20.1 44.2 15.8 14.3 64.7 55.6 14.7 57.8 88.7 60.3 26.2 18.0 78.6 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase, non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 2: 152.9;Basal keratinocytes: 97.1;Rod photoreceptor cells: 171.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 3.0;MAIT T-cell: 2.3;memory CD4 T-cell: 2.2;non-classical monocyte: 4.9" "Group enriched" "Detected in many" 7 "monocytes: 4.9;T-cells: 2.3" "Cell line enhanced" "Detected in many" "AF22: 45.2;RT4: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 10.3 5.9 10.8 2.7 16.9 0.7 9.9 5.7 11.6 15.9 4.1 13.0 7.6 1.2 10.8 21.2 18.7 11.4 6.5 5.3 10.4 5.7 22.1 1.6 18.0 4.3 16.9 7.9 24.1 4.3 26.6 38.3 3.0 14.2 12.0 2.4 39.0 5.9 9.4 1.0 43.0 2.3 8.7 10.3 3.5 3.6 12.2 17.6 1.9 16.9 12.4 11.8 15.7 17.6 0.0 0.5 0.1 4.9 0.1 2.3 0.1 5.1 2.6 45.2 4.4 19.1 16.7 0.0 9.5 19.4 3.6 4.6 0.0 2.6 0.0 2.1 10.5 1.3 17.0 7.8 14.3 7.0 0.1 5.8 4.3 5.6 0.0 2.3 7.5 0.0 10.7 4.6 2.6 8.7 7.6 0.0 0.0 0.0 7.4 0.0 2.3 0.6 2.7 10.3 0.0 1.9 1.5 0.0 0.0 13.8 21.5 2.6 3.8 2.8 6.3 5.2 7.6 3.7 0.2 0.0 3.5 2.7 0.0 1.2 7.7 0.0 0.0 3.7 0.0 1.5 0.0 0.2 0.0 0.2 3.0 2.3 0.0 2.2 0.3 0.5 0.0 0.0 0.0 0.1 0.1 4.9 0.0 0.1 0.1 10.8 16.9 5.7 11.6 10.4 5.7 16.9 7.9 14.2 17.6 44.7 152.9 0.0 21.0 97.1 9.8 1.7 10.2 32.1 75.1 45.4 86.4 0.2 3.3 4.3 20.2 2.2 0.0 0.0 3.0 0.1 20.2 12.1 4.7 0.0 0.2 1.6 4.6 1.8 2.2 14.8 42.3 5.7 18.6 0.0 0.5 14.1 4.3 3.5 30.8 9.2 171.6 12.9 12.5 24.4 21.6 86.9 0.2 4.4 0.2 45.5 PTPN14 PEZ ENSG00000152104 "Protein tyrosine phosphatase, non-receptor type 14" Q15678 1 214348696-214552449 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 1: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011469, HPA053864, CAB069441" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "CAB011469: AB_299202, CAB069441: , HPA053864: AB_2682281" "unprognostic (1.54e-1)" "unprognostic (8.19e-2)" "unprognostic (5.42e-5)" "unprognostic (1.42e-1)" "unprognostic (2.91e-1)" "unprognostic (5.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (2.84e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.29e-4)" "unprognostic (7.43e-2)" "unprognostic (8.34e-3)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "unprognostic (4.81e-3)" 13.6 10.0 3.0 6.5 2.4 0.2 15.0 0.8 3.7 13.6 8.5 2.6 11.0 1.0 15.4 8.0 8.6 9.2 9.7 7.0 3.5 1.9 11.2 2.0 12.2 6.6 2.4 1.3 11.8 5.0 6.3 4.0 13.2 4.9 10.6 2.9 7.2 9.2 23.4 21.6 18.8 3.5 9.4 4.3 5.3 5.7 8.3 2.4 1.4 8.1 6.9 3.7 12.4 17.7 1.0 0.5 1.9 0.4 1.0 0.6 0.1 8.8 3.9 3.2 4.7 5.6 9.6 9.5 10.1 9.4 7.7 6.5 7.9 4.6 0.0 11.2 23.4 4.4 7.9 4.4 11.2 13.2 0.1 3.3 0.8 11.3 1.5 10.2 0.1 0.4 7.1 11.8 13.4 21.6 12.7 14.9 0.3 0.0 0.1 18.6 0.9 0.1 0.1 7.0 1.6 4.3 0.1 16.2 0.0 13.9 4.5 0.0 0.7 12.5 8.2 5.1 11.9 8.1 0.3 26.5 18.1 7.1 6.4 14.2 0.5 0.0 0.0 9.7 0.1 15.0 1.3 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.4 0.1 1.0 0.5 0.6 1.9 1.0 0.4 0.5 0.6 0.1 3.0 2.4 0.8 3.7 3.5 1.9 2.4 1.3 4.9 2.4 68.5 15.9 0.5 27.7 50.3 0.4 17.5 2.5 21.4 44.3 27.9 0.0 30.2 6.6 12.0 8.1 42.7 0.4 0.0 9.4 11.6 27.8 19.5 1.1 0.8 4.0 0.0 3.4 36.8 1.2 4.0 24.2 2.5 10.1 0.0 5.0 3.3 20.7 0.0 27.6 12.5 1.3 19.4 20.6 0.7 7.2 31.6 20.3 1.8 2.9 24.0 PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase, non-receptor type 18" Q99952 2 130356007-130375409 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" NA NA 550000 "Intermediate filaments" "CAB012174: AB_2173224, HPA053367: AB_2732579" "unprognostic (3.11e-3)" "unprognostic (2.89e-3)" "unprognostic (1.67e-3)" "unprognostic (1.73e-3)" "unprognostic (5.81e-3)" "unprognostic (3.08e-3)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (4.65e-1)" "unprognostic (2.10e-2)" "unprognostic (7.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.52e-2)" "unprognostic (1.00e-2)" "unprognostic (3.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.85e-3)" 12.8 7.1 11.0 16.7 13.5 18.9 22.3 26.8 13.7 15.3 22.8 6.6 25.7 16.6 9.3 11.0 11.3 13.3 21.3 7.5 9.8 8.5 13.9 19.2 16.9 29.2 8.4 9.5 7.8 28.9 6.4 11.0 9.4 6.9 17.8 19.3 7.9 18.5 24.0 11.0 6.9 28.8 10.5 9.1 37.7 16.0 3.3 9.1 1.6 13.0 7.1 35.5 11.0 10.7 7.6 7.4 6.2 17.1 2.8 6.6 10.2 5.8 3.9 1.6 7.9 9.9 6.8 16.4 3.0 2.7 3.9 4.4 7.8 9.0 21.9 3.0 7.3 1.8 6.7 6.9 6.8 3.8 9.9 3.8 7.9 4.7 9.2 5.1 7.7 21.5 8.0 5.6 4.3 5.9 0.8 7.4 4.9 7.4 16.7 7.4 11.4 1.4 13.4 1.6 12.6 4.3 13.3 4.6 29.6 7.7 3.6 10.1 2.6 5.3 19.0 8.7 1.6 6.6 11.4 6.9 5.6 6.3 3.0 2.8 2.6 0.7 21.1 8.5 7.0 6.0 6.2 7.8 6.1 6.6 10.8 4.1 7.6 4.4 6.3 6.7 4.5 2.7 5.4 4.9 2.8 17.1 7.4 5.6 10.2 11.0 13.5 26.8 13.7 9.8 8.5 8.4 9.5 6.9 9.1 26.8 22.9 49.5 26.1 5.8 13.5 8.1 20.4 18.7 12.5 34.9 3.9 12.1 46.4 16.6 0.7 21.5 49.1 0.0 39.9 25.3 13.3 43.8 35.7 18.1 76.6 9.5 46.7 17.2 79.3 0.9 17.5 52.8 32.1 16.2 50.4 12.4 23.4 56.1 10.6 25.1 10.0 19.4 19.8 3.0 4.1 5.1 9.6 39.8 38.3 27.6 PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase, non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm NA NA Nucleoplasm "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" 16.7 12.5 12.6 27.0 14.3 33.7 19.9 32.6 19.2 14.7 15.0 7.8 17.8 12.9 12.2 14.9 17.0 13.7 15.7 12.8 13.1 6.8 13.6 20.5 21.6 30.3 15.3 10.3 22.1 28.2 10.4 27.2 13.3 13.8 14.4 17.1 7.9 26.3 16.0 13.1 16.0 15.3 11.8 24.7 24.2 13.1 9.4 15.9 61.3 14.7 11.7 28.9 16.5 15.8 29.1 32.8 19.9 28.0 31.7 29.2 19.6 12.0 7.4 8.6 2.8 9.9 17.8 8.4 8.1 18.0 17.4 15.6 16.0 17.5 19.0 13.7 8.3 19.5 7.3 14.0 22.2 22.9 7.3 8.4 13.4 6.4 16.6 13.6 31.5 12.8 14.9 21.1 15.8 31.4 10.7 8.8 20.8 13.0 25.9 13.9 13.8 31.4 26.0 10.3 49.8 8.6 10.6 13.6 21.5 14.6 19.4 15.5 8.0 16.4 9.7 14.0 9.6 8.1 18.1 6.7 22.1 21.3 16.4 17.4 8.3 8.3 27.5 10.4 17.3 9.2 11.5 28.0 19.9 21.0 24.6 28.2 29.1 24.8 23.1 32.8 20.3 18.3 20.0 10.2 31.7 22.8 28.0 29.2 19.6 12.6 14.3 32.6 19.2 13.1 6.8 15.3 10.3 13.8 15.9 32.8 62.4 68.6 84.1 53.1 42.4 13.2 38.2 33.5 60.3 14.0 98.2 46.3 11.6 47.9 16.6 28.1 29.6 23.3 59.5 44.8 31.3 89.2 55.4 27.0 47.0 14.3 31.0 16.5 81.8 19.2 27.0 82.9 21.9 111.8 30.9 14.8 39.1 38.6 24.1 17.3 84.6 19.4 21.1 15.4 50.3 43.8 67.9 68.2 36.2 140.6 PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase, non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.2" "Cell type enhanced" "Detected in many" 10 "Distal tubular cells: 18.3;Early spermatids: 42.1;Late spermatids: 22.4;Spermatocytes: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "HDLM-2: 32.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" NA NA "Centriolar satellite" "HPA043337: AB_2678436, HPA046896: , HPA048310: AB_2680350, HPA069148: " "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (2.82e-3)" "unprognostic (6.78e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (8.34e-2)" 1.2 9.7 1.0 1.9 3.1 0.0 3.4 3.4 5.4 0.8 1.3 1.0 5.0 1.1 1.4 0.4 3.4 1.0 0.5 8.8 1.4 3.4 4.3 0.6 0.6 0.2 2.4 0.8 1.6 3.9 0.0 2.3 0.3 11.7 1.1 1.5 1.2 7.8 3.2 11.0 5.6 1.0 0.6 1.2 1.0 1.0 13.2 0.0 0.2 1.9 1.7 0.5 1.0 1.0 2.8 2.2 0.0 0.0 2.3 3.1 0.7 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 1.5 0.9 6.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 2.8 1.7 0.4 1.1 0.6 2.2 3.1 0.0 2.3 0.0 2.2 1.3 0.7 1.0 3.1 3.4 5.4 1.4 3.4 2.4 0.8 11.7 0.0 0.0 1.0 0.0 1.7 0.0 5.8 12.1 0.0 6.7 4.5 8.7 5.9 0.0 18.3 1.3 42.1 0.0 0.0 0.0 0.8 0.1 1.0 0.6 0.0 0.5 0.4 11.1 1.2 1.8 0.0 22.4 0.0 0.0 0.0 1.0 0.1 5.4 2.4 0.0 6.7 12.9 2.7 0.0 0.3 17.9 10.9 0.0 0.1 0.0 0.6 0.9 PTPN21 "PTPD1, PTPRL10" ENSG00000070778 "Protein tyrosine phosphatase, non-receptor type 21" Q16825 14 88465778-88554733 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 1: 53.6;Syncytiotrophoblasts: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 23.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB011468, HPA073999" Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centriolar satellite" "CAB011468: AB_442979, HPA073999: AB_2732247" "unprognostic (2.18e-1)" "unprognostic (4.21e-2)" "unprognostic (7.60e-2)" "unprognostic (3.09e-2)" "unprognostic (4.60e-2)" "unprognostic (5.71e-2)" "unprognostic (6.55e-2)" "unprognostic (5.19e-3)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-3)" "unprognostic (3.04e-3)" "prognostic favorable (3.16e-9)" "unprognostic (6.52e-2)" "unprognostic (2.69e-1)" "unprognostic (2.56e-1)" "unprognostic (7.67e-2)" 10.5 4.7 5.3 8.6 7.3 0.0 13.2 4.4 5.8 10.7 8.7 10.7 7.4 4.9 10.6 10.7 8.9 8.3 12.7 17.4 7.4 4.2 8.1 6.0 15.3 1.6 6.6 4.2 15.8 7.8 10.6 3.9 15.6 6.4 11.9 6.5 12.6 6.5 10.5 8.8 24.2 10.5 15.7 7.3 3.7 7.4 15.2 6.5 0.8 16.0 8.4 3.1 12.0 26.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 3.6 2.9 7.7 3.0 8.2 7.2 8.0 9.8 7.5 5.8 8.1 5.2 6.6 0.0 2.4 12.4 5.2 3.4 1.1 3.4 8.5 0.2 1.7 0.0 3.2 2.1 9.2 0.0 0.1 4.7 6.8 4.8 5.8 7.5 4.7 0.0 1.1 0.1 14.8 3.0 0.0 0.1 2.2 3.9 5.6 0.0 23.1 0.0 5.0 2.6 0.5 9.0 5.6 14.1 3.2 6.8 6.9 1.5 9.2 10.8 8.5 4.4 6.7 0.3 1.2 0.0 4.0 0.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.3 4.4 5.8 7.4 4.2 6.6 4.2 6.4 6.5 53.6 5.9 0.0 4.0 9.3 7.3 31.1 5.1 9.4 7.9 7.0 33.4 7.6 0.0 4.4 12.7 4.5 9.3 0.0 7.2 4.4 9.3 7.8 2.3 9.0 1.6 1.6 4.6 7.4 1.2 3.5 15.8 0.7 0.0 0.0 14.6 4.9 8.2 5.8 25.5 3.3 9.0 0.0 8.5 12.1 6.1 10.5 85.2 0.0 4.6 4.7 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase, non-receptor type 22" Q9Y2R2 1 113813811-113871759 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease mutation, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.6;lymphoid tissue: 46.0" "Cell type enhanced" "Detected in many" 15 "B-cells: 29.6;granulocytes: 26.6;Kupffer cells: 19.2;Macrophages: 20.5;T-cells: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 33.5;HL-60: 13.3;U-266/70: 14.4;U-698: 18.0;U-937: 13.6" "Region enriched" "Detected in single" 10 "cerebellum: 5.9" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 4.2 1.4 0.5 17.1 0.8 23.6 1.9 1.0 0.5 2.4 3.3 0.3 1.0 4.1 2.0 2.2 2.0 1.7 3.2 2.5 0.6 0.7 3.4 1.8 9.0 14.9 0.7 0.4 1.5 2.4 0.0 0.9 0.9 1.0 1.7 2.8 1.3 2.7 3.0 0.6 1.0 9.9 0.9 2.1 19.0 3.1 1.1 0.4 46.0 1.5 2.4 12.8 4.8 1.7 7.2 6.2 17.2 3.5 7.5 14.9 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.3 0.0 0.2 33.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 3.1 0.0 4.7 0.0 0.0 0.1 13.3 10.5 3.0 0.0 1.4 0.1 2.7 5.2 8.4 0.0 7.7 5.1 0.1 9.4 7.5 0.0 0.0 0.0 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 2.4 8.0 0.1 0.1 0.2 14.4 3.0 18.0 5.5 13.6 0.0 10.2 3.5 17.2 12.8 0.9 14.9 7.2 6.5 10.1 6.2 4.7 3.9 9.4 1.7 7.5 0.4 3.7 10.0 4.6 0.5 0.8 1.0 0.5 0.6 0.7 0.7 0.4 1.0 0.4 0.0 9.2 29.6 0.2 2.3 0.4 0.5 0.0 4.0 0.0 1.8 2.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.5 0.2 0.9 0.2 26.6 0.6 7.1 0.0 0.0 0.6 19.2 0.6 0.0 20.5 3.3 1.8 1.0 0.0 0.6 0.0 0.0 0.0 0.4 12.9 0.9 0.3 0.2 2.4 0.1 65.4 1.7 0.2 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase, non-receptor type 23" Q9H3S7 3 47381011-47413441 "Enzymes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Nucleoplasm, Nuclear bodies" Vesicles "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favorable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 15.9 18.5 23.1 17.4 22.3 19.2 21.6 22.8 25.0 18.1 12.5 21.4 14.6 20.7 20.0 15.1 17.2 17.2 12.8 13.2 17.9 11.7 16.4 13.0 16.8 17.8 24.6 23.7 23.4 19.4 53.4 29.9 17.1 20.5 16.9 10.4 15.2 20.8 19.0 25.7 25.9 16.0 16.0 20.3 19.2 17.9 17.8 22.7 9.7 24.8 9.7 11.1 17.7 18.1 1.4 1.1 3.7 1.2 0.9 1.5 0.8 13.0 18.6 10.4 13.4 13.6 10.5 10.0 11.9 11.9 11.2 9.5 15.7 12.9 9.3 11.0 13.5 19.9 11.7 8.9 12.9 5.4 8.6 9.6 12.8 13.6 14.6 15.0 7.5 17.4 13.9 13.3 14.5 14.9 7.9 13.7 7.9 9.5 12.8 11.9 18.3 7.1 6.3 11.1 9.1 13.1 4.4 5.0 11.2 8.4 25.3 5.5 13.0 10.5 22.4 8.7 6.6 12.8 7.2 13.7 17.1 14.5 23.7 16.8 18.4 12.0 5.4 18.6 7.1 12.1 3.7 1.2 0.0 0.8 0.5 0.6 1.4 0.6 1.3 0.4 0.7 0.6 0.8 1.4 0.9 0.5 1.1 1.5 0.8 23.1 22.3 22.8 25.0 17.9 11.7 24.6 23.7 20.5 22.7 8.9 6.5 1.5 4.4 7.1 11.3 6.2 10.2 10.7 7.9 5.2 13.7 8.5 1.7 9.1 1.4 11.1 14.2 0.0 7.6 6.5 6.1 7.9 2.3 9.6 11.6 15.9 7.0 12.3 11.1 2.1 17.8 7.8 11.8 9.0 15.6 9.2 11.8 8.6 12.7 8.2 13.8 6.5 6.2 7.4 10.9 9.5 7.8 4.3 11.5 6.3 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase, non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 38.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in many" "OE19: 16.9;RPTEC TERT1: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "HPA038343: AB_10671741, HPA046728: AB_2679776" "prognostic unfavorable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 2.7 1.9 3.4 4.8 5.0 0.0 4.8 2.1 11.1 4.4 9.4 2.0 10.7 7.6 3.2 13.4 10.3 6.4 6.3 12.1 3.1 2.8 28.8 21.1 4.9 0.5 1.2 3.9 1.5 17.0 10.6 4.9 14.5 4.5 4.7 6.5 3.8 13.1 13.6 38.1 18.8 18.8 0.8 0.9 0.9 5.9 2.1 0.0 1.1 9.4 7.2 9.5 4.1 5.5 0.6 0.3 2.8 0.6 0.3 0.3 0.1 6.3 7.9 0.3 2.1 0.0 0.0 12.6 1.4 0.0 1.7 1.9 4.2 10.4 0.0 1.4 0.1 4.4 15.2 2.2 8.9 1.8 3.5 4.8 0.0 3.8 4.3 0.0 0.0 0.1 0.1 9.6 2.2 4.6 0.7 0.0 2.7 0.0 0.1 0.1 8.0 10.9 1.9 1.0 16.9 5.9 0.0 2.6 0.1 20.6 12.3 5.2 1.1 3.5 13.0 0.0 4.5 7.4 1.0 0.0 0.6 5.0 0.8 0.0 6.3 10.2 0.0 6.8 0.0 4.5 0.4 0.6 0.8 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.6 0.3 0.3 2.8 0.3 0.6 0.3 0.1 0.1 3.4 5.0 2.1 11.1 3.1 2.8 1.2 3.9 4.5 0.0 14.9 25.0 0.0 20.1 10.5 9.6 46.0 20.4 24.1 19.4 29.6 0.0 19.8 14.9 13.1 20.8 2.2 25.4 0.0 16.7 20.5 3.6 23.7 1.1 32.7 2.2 0.0 12.6 4.3 0.0 12.7 1.1 1.9 3.3 1.0 16.5 0.3 22.0 23.5 1.8 16.1 2.1 6.5 6.2 0.9 11.7 18.1 9.0 0.8 17.3 26.2 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase, non-receptor type 4" P29074 2 119759631-119983818 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bipolar cells: 53.9;Cone photoreceptor cells: 98.2;Horizontal cells: 152.6;Rod photoreceptor cells: 80.5;T-cells: 90.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 16 "NK-cells: 12.2;T-cells: 19.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favorable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 6.8 6.9 10.0 5.9 12.2 7.3 7.2 37.4 16.9 9.6 5.5 7.2 5.2 8.1 7.2 6.6 6.9 8.9 6.3 8.9 10.2 8.4 12.0 6.6 8.0 7.9 7.3 13.1 8.9 6.3 11.6 16.3 4.1 8.3 6.2 4.0 7.1 7.9 6.6 11.2 5.8 5.5 4.7 7.3 9.2 8.9 7.7 6.5 18.9 22.5 6.8 6.5 5.3 5.8 0.5 0.3 0.9 0.4 12.2 19.3 4.7 7.4 4.4 5.8 7.7 5.2 5.4 9.9 3.4 9.6 1.9 5.3 6.6 11.6 5.4 8.2 3.8 5.8 6.6 4.5 5.3 5.2 12.6 3.8 3.7 4.2 6.2 3.5 3.8 2.8 4.9 10.0 9.0 4.1 6.6 8.5 5.5 6.4 5.5 5.1 5.7 5.2 4.4 7.6 4.2 7.2 3.6 10.0 7.6 7.0 10.2 7.6 9.4 4.7 6.0 3.9 5.1 2.9 2.4 10.6 0.3 6.7 2.3 4.1 9.5 13.2 6.8 5.1 0.2 3.2 0.2 0.2 0.9 19.3 0.3 15.6 0.5 9.6 15.1 0.3 0.5 3.2 11.0 0.7 12.2 0.4 0.3 5.6 4.7 10.0 12.2 37.4 16.9 10.2 8.4 7.3 13.1 8.3 6.5 3.0 10.5 14.0 12.8 7.2 53.9 13.9 10.2 6.7 6.8 15.7 98.2 8.5 6.6 6.1 3.8 12.8 8.1 0.0 6.3 9.0 7.6 8.7 11.5 9.0 3.6 152.6 8.7 13.5 5.6 7.1 16.1 5.3 8.5 7.2 7.8 23.6 5.5 10.1 13.4 10.4 80.5 0.0 5.0 21.2 20.6 5.8 3.1 90.0 10.6 7.8 PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase, non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 70.0" "Cell type enhanced" "Detected in some" 15 "Cardiomyocytes: 2.4;Distal tubular cells: 1.7;Endothelial cells: 2.4" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Region enhanced" "Detected in many" "basal ganglia: 70.0" "Cell type enriched" "Detected in single" 9 "basophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HMC-1: 3.7;NTERA-2: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: AB_2686487" "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" 2.5 1.6 16.3 1.1 70.0 1.1 1.2 0.9 47.5 1.5 1.1 0.4 0.0 1.1 1.2 1.0 1.3 1.7 1.4 4.3 9.1 8.6 1.1 0.9 2.7 1.1 3.5 16.0 2.5 1.2 1.5 0.5 0.9 6.1 1.6 1.4 0.0 1.3 1.7 1.8 1.0 1.4 1.4 2.1 1.3 1.3 3.4 9.3 0.0 1.2 0.0 1.0 1.5 0.3 0.1 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 3.7 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 5.8 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.4 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 70.0 0.9 25.1 9.1 8.6 3.5 16.0 6.1 9.3 0.0 0.0 0.0 0.0 0.1 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase, non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 107.1;lymphoid tissue: 69.0" "Group enriched" "Detected in many" 5 "B-cells: 106.2;Early spermatids: 45.6;granulocytes: 130.8;Hofbauer cells: 168.2;Kupffer cells: 145.1;Macrophages: 118.2;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.7;HL-60: 25.5;HMC-1: 112.6;THP-1: 43.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli NA NA 7400000 Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favorable (1.87e-4)" "prognostic unfavorable (5.42e-4)" "prognostic favorable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favorable (2.64e-8)" 6.6 8.8 2.4 42.9 4.4 27.7 4.6 1.2 2.7 2.8 7.0 5.1 4.7 7.5 3.7 8.8 7.0 5.0 9.8 2.9 3.1 2.3 7.0 6.8 25.4 58.1 5.2 1.8 2.3 6.7 2.7 5.6 7.7 3.9 5.6 5.2 3.6 10.6 7.0 1.3 6.1 21.0 2.6 4.9 69.0 6.6 1.5 3.3 31.4 6.3 4.1 50.7 8.5 4.2 63.9 38.0 107.1 103.2 22.2 28.2 63.2 2.9 5.6 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 3.0 6.6 2.0 1.5 0.0 0.0 3.4 0.0 3.9 0.0 1.2 1.2 28.7 0.6 2.4 0.0 25.5 112.6 0.0 2.8 0.0 1.2 0.0 0.0 10.3 0.0 0.2 0.0 6.1 9.2 14.9 1.5 6.8 0.9 8.4 0.0 14.5 3.1 5.5 0.5 0.0 0.9 4.6 0.0 4.1 1.4 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 11.2 0.1 54.4 35.9 107.1 28.2 71.3 18.2 62.3 13.7 21.0 38.0 63.9 15.8 19.9 66.7 22.2 103.2 10.0 14.4 63.2 2.4 4.4 1.2 2.7 3.1 2.3 5.2 1.8 3.9 3.3 6.0 18.1 106.2 8.1 8.0 0.0 1.6 12.7 12.0 11.4 5.2 0.0 21.7 13.3 12.3 45.6 4.1 15.8 23.3 13.5 15.5 3.5 4.1 130.8 10.2 168.2 0.0 23.7 9.8 145.1 8.7 0.9 118.2 13.5 6.4 12.0 0.4 11.8 17.3 0.0 10.5 0.6 6.5 2.3 0.3 1.1 7.5 15.4 105.5 15.6 5.6 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase, non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;lymphoid tissue: 63.7" "Group enriched" "Detected in many" 5 "B-cells: 40.6;granulocytes: 137.4;T-cells: 156.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basal ganglia: 9.4;thalamus: 2.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 17.0;NK-cells: 9.9;T-cells: 10.6" "Cell line enhanced" "Detected in some" "HEL: 16.7;HL-60: 36.3;HMC-1: 48.9;NB-4: 15.8;THP-1: 16.7;U-937: 26.2" "Region enriched" "Detected in single" 10 "basal ganglia: 5.5" "Region enriched" "Detected in all" 4 "basal ganglia: 10.9" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" NA NA Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 2.6 3.1 0.5 27.1 9.4 24.5 0.6 0.4 0.5 0.6 2.3 0.6 0.0 3.0 0.7 0.6 1.7 0.8 2.9 0.5 0.6 0.8 1.1 0.9 3.2 16.5 1.2 0.2 0.6 0.6 0.0 0.7 0.4 0.8 1.3 1.9 0.7 5.3 0.3 0.4 0.6 3.7 0.9 1.6 15.4 1.4 12.7 2.9 63.7 0.9 0.6 24.8 2.9 0.8 2.6 2.6 17.0 1.1 9.9 10.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 16.7 0.0 0.0 0.0 36.3 48.9 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.7 1.5 0.0 0.0 4.9 15.8 0.0 0.0 0.0 0.7 0.0 12.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.1 0.0 0.0 7.4 1.8 10.5 0.0 26.2 0.0 11.5 1.1 17.0 10.6 1.1 9.5 1.9 7.1 10.5 2.0 2.6 5.3 6.4 7.1 9.9 0.4 2.6 9.0 2.8 0.5 9.4 0.4 0.5 0.6 0.8 1.2 0.2 0.8 2.9 3.0 9.0 40.6 1.0 2.1 2.4 0.7 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.2 0.4 2.9 0.0 0.0 0.0 0.1 1.7 0.5 137.4 0.5 15.6 0.0 0.0 4.9 6.2 1.3 4.9 23.4 8.5 9.0 0.0 5.6 0.1 0.0 2.1 0.6 4.4 0.0 0.9 0.9 0.4 2.0 0.7 156.8 0.0 0.5 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase, non-receptor type 9" P43378 15 75463251-75579289 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles NA NA Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 16.8 12.8 15.0 11.8 17.7 9.2 15.7 11.1 20.0 17.4 22.4 10.5 12.0 17.0 18.9 16.4 10.9 16.4 13.5 12.2 13.1 14.6 17.9 14.0 16.0 12.6 11.6 12.4 16.0 12.3 16.6 12.5 18.9 13.2 16.9 19.5 18.4 14.6 21.9 6.8 11.8 30.6 17.6 15.6 15.6 13.4 8.7 7.5 16.3 34.4 8.0 13.9 14.7 15.3 3.3 5.9 4.6 5.7 6.7 7.2 2.9 9.2 11.2 17.5 11.6 13.1 14.5 5.7 14.0 21.7 17.7 16.1 6.7 14.1 15.0 11.3 23.7 14.2 14.1 37.6 16.0 17.9 18.6 9.5 8.4 8.0 7.1 19.7 12.8 13.0 18.7 16.8 14.1 22.2 18.1 14.8 10.0 5.6 5.5 19.9 6.1 9.0 12.0 16.0 8.4 5.7 17.8 8.7 4.1 22.3 15.1 6.9 14.3 19.8 11.0 21.4 17.5 5.7 22.0 17.0 17.0 5.5 11.1 14.8 8.1 8.4 14.0 9.9 19.4 16.6 4.6 4.3 4.2 7.2 5.7 5.7 3.3 5.0 6.1 5.9 2.3 2.1 3.9 0.7 6.7 5.4 3.9 3.1 2.9 15.0 17.7 11.1 20.0 13.1 14.6 11.6 12.4 13.2 7.5 6.0 12.0 13.4 6.8 3.0 11.0 3.1 10.2 8.1 9.1 10.4 7.9 13.9 13.3 9.2 2.4 8.0 20.3 0.0 8.6 3.5 11.9 8.9 15.0 9.9 16.4 3.2 6.9 22.1 18.1 3.5 11.5 20.8 6.8 16.2 12.2 5.4 14.2 10.5 25.8 8.4 17.5 12.9 8.6 5.2 7.0 2.9 8.5 12.9 12.1 12.7 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase, receptor type A" P18433 20 2864184-3039076 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA 21000 Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favorable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 21.9 18.5 55.6 14.3 48.6 16.4 23.3 44.5 56.0 29.7 19.7 37.5 9.4 14.7 26.3 18.7 22.7 26.5 21.3 14.0 45.9 41.1 22.1 13.5 21.6 16.9 38.0 46.7 28.6 14.9 41.5 23.4 29.0 52.5 23.5 20.0 18.5 16.7 21.8 8.2 21.0 15.3 25.7 52.6 17.9 16.3 27.4 30.4 20.6 32.4 8.5 20.4 22.9 19.2 7.7 5.7 7.9 6.7 6.2 11.0 3.7 21.0 12.9 37.2 11.4 41.2 75.1 7.9 15.8 31.0 19.6 24.1 15.3 29.2 13.8 12.5 21.2 19.8 22.6 15.0 22.6 22.2 21.3 9.6 19.6 5.4 19.4 14.7 19.7 9.3 33.5 23.5 16.2 17.1 24.2 27.1 19.9 19.7 17.7 19.4 8.6 22.7 22.3 14.3 18.9 10.3 17.4 18.0 17.2 16.7 16.3 20.6 19.7 15.3 26.1 23.5 16.9 16.3 16.9 19.4 17.6 8.7 19.5 13.9 13.0 18.0 18.2 8.1 18.7 16.4 7.9 4.8 7.5 11.0 4.8 9.0 7.7 7.4 7.9 3.7 5.1 7.4 9.0 6.0 6.2 6.7 5.7 8.1 3.7 55.6 48.6 44.5 56.0 45.9 41.1 38.0 46.7 52.5 30.4 20.8 16.3 29.4 29.9 14.1 87.6 6.5 45.9 17.4 27.3 43.6 29.5 25.3 23.2 13.3 11.8 26.9 31.5 23.3 13.4 35.4 36.1 29.8 23.0 28.0 33.5 66.7 42.6 43.6 35.2 12.5 55.8 21.8 35.4 10.8 27.0 77.3 13.8 25.8 46.0 19.2 55.1 38.8 26.4 51.2 75.4 15.1 27.3 39.5 26.2 27.6 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase, receptor type B" P23467 12 70515866-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Endothelial cells: 113.4;Ito cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "memory B-cell: 3.5" "Lineage enriched" "Detected in single" 7 "B-cells: 3.5" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;hTERT-RPE1: 9.1;HUVEC TERT2: 28.0;TIME: 40.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 6700000 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 23.5 7.0 4.5 5.5 7.0 0.1 22.9 3.6 6.1 11.3 8.0 4.3 7.1 5.3 17.1 8.5 5.8 8.2 11.4 17.6 6.2 5.1 18.7 12.0 39.9 3.3 6.9 4.6 5.5 4.4 4.9 5.7 23.3 7.8 6.1 8.2 16.0 3.6 7.1 11.8 4.7 7.4 13.3 7.3 22.9 5.2 3.7 4.3 0.7 14.0 12.2 2.6 6.5 14.7 3.5 0.1 0.2 0.0 0.4 0.3 0.2 1.9 0.1 0.8 0.1 0.0 0.0 0.4 0.4 1.9 1.0 2.4 0.0 1.5 0.7 11.3 0.3 0.1 6.9 0.1 0.3 3.6 0.6 0.3 0.1 0.8 0.5 0.1 0.3 0.0 0.0 0.3 2.8 0.0 9.1 28.0 0.0 1.5 0.5 0.6 0.0 0.0 0.0 1.0 1.9 0.4 0.0 0.7 0.4 5.2 0.8 0.0 0.4 0.7 0.0 1.6 0.2 0.0 0.6 40.9 0.4 0.4 0.1 2.4 0.5 0.4 0.3 0.2 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 4.5 7.0 3.6 6.1 6.2 5.1 6.9 4.6 7.8 4.3 0.0 19.9 13.7 0.8 3.3 5.4 9.2 17.8 0.0 1.2 3.5 0.0 0.0 0.0 1.4 4.3 113.4 4.3 46.7 0.8 0.0 1.9 0.6 23.3 2.0 0.3 4.8 0.0 448.7 26.3 2.5 1.1 2.0 5.0 0.0 4.8 0.3 7.2 14.4 0.0 0.0 0.8 0.0 0.9 0.7 0.5 1.4 0.0 1.7 5.2 0.6 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase, receptor type D" P23468 9 8314246-10612723 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;parathyroid gland: 37.5" "Cell type enhanced" "Detected in many" 15 "Bipolar cells: 110.1;Intestinal endocrine cells: 34.0;Muller glia cells: 44.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.5;HAP1: 5.1;HSkMC: 8.0;NTERA-2: 5.7;RH-30: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2500000 Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.6 1.7 19.7 1.5 19.2 1.1 1.1 27.9 32.1 5.6 5.4 21.7 0.2 4.0 3.6 1.8 1.5 3.6 2.6 3.0 18.0 13.5 11.4 4.2 3.4 0.9 17.9 22.3 12.7 1.7 37.5 4.4 9.4 15.1 3.3 5.3 1.9 1.1 2.0 1.0 1.2 4.6 2.8 29.7 1.4 1.7 2.5 18.5 0.0 3.2 0.0 1.0 2.7 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 23.5 0.0 0.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 2.6 4.8 0.6 0.0 0.0 0.0 0.2 8.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 5.7 0.0 1.5 2.9 8.7 0.0 2.1 0.0 4.0 0.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.7 19.2 27.9 32.1 18.0 13.5 17.9 22.3 15.1 18.5 0.0 2.7 0.0 0.2 0.5 110.1 4.6 25.5 0.0 2.3 5.2 15.7 0.3 0.0 2.5 13.0 0.4 10.1 0.0 0.0 0.1 7.6 1.7 0.0 12.8 1.0 4.8 34.0 1.3 0.6 3.7 14.7 0.0 0.0 0.0 14.3 44.7 0.3 3.5 0.0 22.3 7.4 0.0 3.7 1.1 1.1 0.6 0.2 0.0 5.2 0.0 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase, receptor type E" P23469 10 127907061-128085855 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 91.0" "Cell type enhanced" "Detected in many" 10 "Kupffer cells: 141.1;Macrophages: 249.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 91.0;plasmacytoid DC: 65.7" "Group enriched" "Detected in all" 11 "dendritic cells: 65.7;granulocytes: 91.0;monocytes: 25.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 18.8;HUVEC TERT2: 19.8;NB-4: 14.9;TIME: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" NA NA "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 16.8 18.5 12.5 24.0 12.5 39.5 11.0 7.4 15.3 4.8 9.2 14.5 1.6 9.6 5.1 8.1 8.8 6.2 10.7 12.3 15.0 12.2 4.4 4.8 22.5 20.0 12.5 6.5 4.3 3.1 3.4 6.5 8.0 9.8 4.5 9.8 4.8 7.0 3.1 1.9 4.9 12.7 7.7 14.3 26.4 7.7 4.3 10.9 11.4 6.6 6.1 12.2 10.0 5.0 1.2 65.7 91.0 25.5 4.0 5.4 4.9 1.9 0.4 0.2 0.0 1.2 0.2 3.6 0.0 0.0 0.8 1.7 0.8 12.0 1.5 1.3 1.0 2.6 1.1 1.0 5.7 0.3 1.8 0.9 0.1 0.7 0.0 2.0 7.4 5.6 0.4 3.3 2.9 5.9 18.8 19.8 4.9 0.0 0.9 1.2 1.8 2.2 14.9 0.1 2.1 0.7 8.8 1.2 2.9 3.3 8.5 0.0 1.2 3.4 0.6 0.1 0.9 0.3 9.4 37.4 0.8 0.8 3.7 4.1 0.4 0.6 2.1 5.5 5.8 0.0 17.4 25.5 19.3 5.4 9.0 3.2 0.9 2.4 3.6 13.3 1.2 1.7 2.9 91.0 4.0 6.8 65.7 3.5 4.9 12.5 12.5 7.4 12.7 15.0 12.2 12.5 6.5 9.8 10.9 77.4 67.6 24.7 47.2 52.9 2.6 15.1 5.1 9.4 33.0 3.5 0.0 33.6 0.0 4.3 1.6 49.4 12.3 0.0 4.0 40.5 9.9 8.3 30.1 1.3 53.6 0.0 6.4 46.1 141.1 1.7 0.6 249.1 23.6 4.6 14.4 0.0 28.7 11.5 0.4 1.9 0.8 0.0 8.1 0.5 1.4 56.6 14.2 52.4 10.2 34.4 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase, receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 261.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 54.6;SK-BR-3: 62.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" NA NA 95000000 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favorable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 37.1 5.5 22.4 10.4 18.1 0.9 30.7 6.8 19.5 14.2 34.3 16.8 34.4 30.7 12.3 33.4 41.4 32.2 20.0 6.3 17.2 15.0 12.0 45.6 15.7 5.8 17.2 18.5 10.4 25.3 17.5 10.3 38.1 16.1 30.9 23.1 5.9 41.9 23.6 2.9 46.8 35.5 16.8 11.2 2.0 21.8 4.3 15.8 4.6 12.5 11.7 14.9 21.4 21.3 0.9 0.0 0.2 0.0 0.0 0.0 0.7 31.0 14.9 9.7 11.5 2.2 0.1 54.6 17.8 7.1 14.7 12.6 15.8 42.3 0.0 5.0 7.8 11.9 24.3 11.3 39.2 17.9 0.3 14.1 0.1 10.2 14.3 6.9 0.2 0.2 2.3 22.6 21.2 35.2 18.6 21.9 1.5 4.7 1.4 5.4 17.9 0.2 0.2 14.8 17.2 4.1 10.8 17.3 0.7 5.7 46.9 14.6 5.4 17.7 62.4 2.3 26.9 18.1 3.3 17.1 0.3 23.6 1.5 23.7 0.6 0.5 0.0 1.4 0.7 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 22.4 18.1 6.8 19.5 17.2 15.0 17.2 18.5 16.1 15.8 145.9 89.7 2.2 43.9 55.8 11.0 4.0 152.8 81.7 63.7 82.0 41.2 48.4 0.0 138.1 4.0 7.0 185.3 0.0 104.8 261.2 17.9 82.4 4.7 141.8 12.4 174.8 96.9 9.2 4.3 6.9 6.4 5.4 11.8 4.6 152.5 28.3 148.7 95.1 6.7 13.9 28.0 0.0 11.0 8.0 34.8 79.8 55.4 2.2 124.5 65.3 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase, receptor type G" P23470 3 61561569-62297613 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Bipolar cells: 91.5;Horizontal cells: 146.2;Ito cells: 89.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 36.2;HSkMC: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 520000000 "Plasma membrane" "HPA000546: , HPA064237: AB_2685221" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 22.2 18.0 12.9 10.1 10.7 1.2 26.1 8.1 16.4 17.2 13.9 5.2 12.0 5.6 15.8 19.0 6.4 13.1 15.7 12.4 24.5 9.9 20.2 8.2 38.9 10.2 8.3 10.5 16.6 6.0 58.6 11.9 13.1 15.1 11.3 8.9 23.3 7.9 17.2 19.2 6.6 8.4 17.4 12.7 9.2 8.7 11.4 5.0 0.1 21.7 7.0 3.2 10.0 14.6 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 11.7 0.0 36.2 18.5 5.7 7.2 11.8 7.7 10.4 5.4 0.2 0.2 4.2 8.5 6.1 0.1 5.6 5.6 12.2 0.6 3.2 0.5 0.0 6.2 12.2 3.0 0.0 26.8 2.3 10.9 13.2 2.5 8.3 0.8 0.0 7.2 6.9 3.1 0.0 0.0 7.2 0.0 0.0 4.7 3.6 0.2 7.9 3.3 0.9 1.9 1.7 0.0 2.8 5.0 0.0 0.1 18.9 10.8 10.3 17.2 6.0 2.3 2.6 0.0 8.2 1.3 13.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 12.9 10.7 8.1 16.4 24.5 9.9 8.3 10.5 15.1 5.0 11.9 25.9 0.8 5.2 8.1 91.5 10.4 7.6 2.7 5.7 21.0 5.9 7.6 5.0 7.9 2.9 41.3 11.0 0.0 1.6 0.6 33.6 7.0 0.0 26.0 15.0 146.2 23.6 89.0 2.2 2.5 61.5 1.8 16.9 1.0 7.6 38.3 4.5 7.0 53.4 13.3 4.8 71.1 52.3 1.0 6.1 4.3 10.5 0.9 11.0 2.2 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase, receptor type H" Q9HD43 19 55181248-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 29.6;intestine: 84.3;lymphoid tissue: 21.2" "Cell type enhanced" "Detected in many" 18 "Enterocytes: 106.7;Paneth cells: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enhanced" "Detected in many" "HHSteC: 9.1;K-562: 10.6;OE19: 22.4;SK-MEL-30: 15.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042300 Approved Mitochondria NA NA Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 0.5 8.9 0.5 5.2 0.7 0.0 0.5 0.5 1.0 0.7 39.9 0.6 0.5 30.1 0.5 0.5 0.6 0.0 29.6 0.5 1.3 1.6 0.6 7.8 0.6 0.5 3.0 0.5 0.6 2.8 0.0 3.0 0.6 0.5 1.0 9.6 0.6 0.5 0.5 0.5 0.0 84.3 0.7 6.9 21.2 10.2 0.5 0.5 0.5 0.5 1.0 0.8 1.1 2.4 0.0 0.7 0.0 1.5 0.0 0.0 0.0 4.9 3.0 0.0 1.2 1.0 2.7 0.0 0.1 2.7 0.5 1.1 1.3 7.0 0.0 0.2 0.5 6.2 0.0 0.0 0.0 0.6 0.0 0.1 0.4 0.1 3.5 9.1 0.0 3.6 0.7 2.2 1.7 2.7 0.3 0.1 0.0 10.6 0.5 0.0 0.0 0.0 0.2 0.0 22.4 7.2 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.0 3.1 15.9 0.0 0.0 1.4 0.0 0.7 1.1 0.3 0.0 0.0 2.6 0.0 0.8 0.1 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.7 0.5 0.5 1.3 1.6 3.0 0.5 0.5 0.5 0.0 0.0 0.0 2.4 1.5 0.0 0.6 20.4 0.0 0.0 1.8 0.0 0.0 0.0 11.7 0.0 0.2 106.7 0.0 22.9 0.0 0.2 3.1 0.0 5.1 0.2 15.9 4.6 1.3 0.0 0.0 0.0 0.8 0.0 1.0 14.0 0.2 20.1 38.6 0.0 0.0 0.3 0.0 0.4 0.0 0.2 1.0 0.1 0.0 15.6 17.9 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase, receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Kupffer cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in all" 4 "granulocytes: 12.2;monocytes: 5.3" "Cell line enhanced" "Detected in many" "EFO-21: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" NA NA 840000000 "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 5.6 3.7 10.4 17.7 13.9 22.6 5.6 4.9 9.5 6.1 9.0 8.8 12.3 8.4 3.9 7.6 2.9 5.0 6.7 5.2 9.5 9.2 13.3 12.2 12.2 22.6 10.8 9.4 3.0 9.1 21.1 14.5 20.3 8.3 7.8 8.1 12.9 12.9 9.0 4.6 4.3 13.4 5.5 6.7 33.0 13.8 3.1 9.9 6.7 18.8 0.9 9.7 6.0 3.9 1.0 1.8 12.2 5.3 1.2 2.1 0.9 3.5 13.5 5.9 3.2 0.9 2.1 2.0 3.6 2.7 6.4 4.8 0.8 20.0 3.3 25.5 9.2 9.6 2.7 9.3 0.9 7.8 21.9 2.5 0.9 16.7 1.2 5.8 1.2 20.8 1.5 0.3 1.7 0.5 15.3 3.9 0.2 1.2 2.2 2.2 7.7 0.0 7.5 4.6 11.5 2.1 0.8 0.7 1.7 24.8 5.3 4.0 1.2 10.1 5.7 9.1 4.5 6.4 9.2 12.5 5.0 5.3 10.0 11.0 0.5 0.7 5.5 5.8 3.8 18.3 0.9 1.5 3.4 2.1 2.5 1.4 1.0 1.2 1.5 1.0 0.7 1.0 1.3 12.2 1.2 5.3 1.8 1.1 0.9 10.4 13.9 4.9 9.4 9.5 9.2 10.8 9.4 8.3 9.9 8.9 21.3 8.0 8.8 0.2 11.1 3.1 17.8 8.1 22.7 36.6 5.9 1.5 0.0 6.5 4.2 2.2 28.4 0.0 4.3 0.6 3.0 20.5 12.8 14.0 26.2 9.5 12.1 2.5 67.6 4.0 0.3 20.6 1.7 10.8 8.5 11.5 8.7 28.1 0.4 10.9 1.0 0.0 3.9 0.2 3.2 0.3 1.6 13.8 5.7 5.4 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase, receptor type K" Q15262 6 127968779-128520674 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.3;naive B-cell: 4.8;naive CD8 T-cell: 1.6" "Group enriched" "Detected in many" 7 "B-cells: 4.8;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 12.0 5.2 18.6 10.7 20.3 1.2 20.9 4.7 24.4 12.2 21.9 25.6 11.2 25.7 12.1 10.3 9.1 13.2 29.6 11.4 17.2 12.6 13.3 23.6 17.4 5.7 20.5 19.3 15.6 25.7 11.4 12.2 17.4 14.9 16.3 23.4 3.9 18.3 17.5 9.1 13.5 27.4 14.6 17.1 6.4 24.6 2.7 23.7 15.3 10.1 6.5 7.6 18.4 15.1 4.8 0.0 0.0 0.0 0.4 1.6 0.2 4.5 4.9 2.9 0.2 6.2 8.3 3.0 12.3 23.8 5.1 4.6 8.1 3.8 0.0 3.7 11.3 14.8 12.9 3.1 9.7 7.2 13.6 4.9 0.1 7.5 11.2 7.6 0.0 0.4 6.1 9.0 10.6 14.5 13.3 13.8 4.4 0.0 0.2 12.4 9.1 6.9 0.0 3.1 8.3 6.3 24.8 6.3 0.8 12.6 9.3 15.5 0.0 12.7 14.2 0.7 3.5 3.9 0.3 23.4 8.0 5.6 15.5 11.1 0.1 1.6 0.0 10.2 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 4.8 0.4 1.6 0.0 0.4 0.0 0.0 0.1 0.2 18.6 20.3 4.7 24.4 17.2 12.6 20.5 19.3 14.9 23.7 23.8 27.4 9.7 78.6 56.3 3.1 19.3 76.5 18.7 33.0 17.4 3.9 21.8 0.0 51.8 3.4 46.7 63.1 0.0 53.2 4.5 30.5 99.0 1.1 36.5 5.1 9.5 42.2 8.0 1.0 2.1 15.8 1.8 16.9 2.8 41.3 7.0 84.8 57.5 17.0 11.2 0.6 58.2 35.8 3.6 5.8 33.2 22.4 1.0 48.9 100.5 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase, receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 4 "Endothelial cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "memory CD8 T-cell: 7.2" "Group enriched" "Detected in many" 50 "dendritic cells: 2.7;T-cells: 7.2" "Cell line enhanced" "Detected in many" "ASC diff: 35.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA NA 76000000 "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 31.4 14.1 9.5 6.3 22.2 0.6 23.6 10.4 17.2 11.0 13.6 6.2 28.1 4.7 15.4 10.9 8.1 13.6 18.1 33.5 10.5 15.0 16.9 6.5 22.0 7.8 8.5 12.0 15.7 7.6 16.3 21.9 18.3 23.2 10.6 6.6 18.3 7.4 21.8 26.0 7.3 8.7 14.1 9.3 12.1 11.0 12.2 9.1 2.9 31.1 7.3 6.3 18.6 25.3 0.0 2.7 0.0 0.0 0.0 7.2 1.4 1.5 11.4 5.5 0.0 35.1 24.4 13.3 14.0 12.3 9.4 14.0 10.4 2.4 0.0 13.8 16.7 0.2 0.1 0.0 4.9 13.1 0.1 2.5 0.0 7.6 5.0 10.0 0.0 0.1 27.6 10.3 5.2 14.9 18.1 9.4 0.0 0.0 4.8 7.5 0.2 4.5 0.1 0.9 3.3 2.5 0.1 4.7 21.1 23.1 19.6 0.5 3.0 0.4 0.0 11.7 9.1 0.0 0.0 9.7 19.4 12.2 9.2 2.4 0.4 0.1 0.0 16.6 0.0 3.6 0.0 0.0 0.0 4.5 0.0 1.8 0.0 6.0 7.2 0.1 0.0 1.7 3.1 0.0 0.0 0.0 2.7 1.0 1.4 9.5 22.2 10.4 17.2 10.5 15.0 8.5 12.0 23.2 9.1 41.7 29.0 0.9 6.8 5.4 24.2 24.1 17.8 22.7 9.1 5.2 2.0 10.4 1.7 15.5 24.0 47.4 0.5 0.0 7.1 2.7 10.2 7.0 2.3 20.2 8.2 0.0 1.7 38.1 8.0 34.9 2.6 5.2 28.7 1.0 1.3 2.8 12.6 0.3 4.9 11.3 1.9 6.5 8.0 3.6 9.8 2.5 10.5 2.5 0.8 5.4 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase, receptor type N2" Q92932 7 157539056-158587788 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6;pancreas: 51.3" "Cell type enhanced" "Detected in many" 7 "Ciliated cells: 84.3;Intestinal endocrine cells: 126.1" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 14.8" "Cell line enhanced" "Detected in some" "AF22: 15.6;HDLM-2: 22.0;NB-4: 22.6;SCLC-21H: 12.5;SH-SY5Y: 12.7;THP-1: 11.1;U-87 MG: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 2.1 10.5 20.1 1.7 33.9 1.0 1.1 6.2 40.6 1.7 4.6 2.9 0.0 5.1 2.0 2.9 1.5 6.9 4.7 1.9 18.2 21.3 2.0 1.2 3.1 2.1 11.3 22.3 5.8 51.3 0.5 20.0 1.5 10.3 10.2 3.7 1.5 3.4 2.6 0.8 0.7 4.2 1.6 5.3 7.7 24.2 2.2 5.2 0.0 5.6 0.3 1.7 2.8 0.6 3.4 1.3 14.8 1.1 1.5 3.5 1.1 0.0 0.2 15.6 1.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.6 0.2 3.7 0.0 0.4 0.0 0.0 22.0 0.2 0.0 0.0 2.5 0.6 0.0 0.0 1.1 0.2 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.0 0.2 6.5 22.6 3.1 5.5 0.8 0.0 0.7 0.1 0.0 0.0 12.5 12.7 0.0 0.0 0.0 0.0 0.0 11.1 3.3 5.1 1.9 0.0 0.4 0.1 0.0 0.0 15.4 9.2 3.7 8.7 1.1 1.6 0.9 0.1 0.3 2.3 1.5 1.1 1.3 3.4 1.4 0.9 14.8 1.5 0.0 0.2 3.5 1.1 20.1 33.9 6.2 40.6 18.2 21.3 11.3 22.3 10.3 5.2 3.0 11.7 10.4 12.5 2.1 31.6 2.2 7.6 84.3 13.6 38.4 9.8 0.4 29.9 15.8 35.1 23.3 4.5 0.0 11.7 0.4 3.9 21.1 18.5 0.8 34.3 11.1 126.1 41.1 11.0 13.1 11.5 6.0 11.8 3.6 39.6 40.1 6.1 5.8 18.4 3.5 6.3 25.8 5.1 41.6 11.7 1.3 0.6 10.0 7.2 22.5 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase, receptor type O" Q16827 12 15322397-15597399 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;intestine: 28.5;kidney: 21.6" "Cell type enhanced" "Detected in some" 7 "Bipolar cells: 16.3;Collecting duct cells: 15.7;Hofbauer cells: 22.6;Horizontal cells: 23.8;Kupffer cells: 17.2;monocytes: 19.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.2;intermediate monocyte: 10.5;memory B-cell: 8.3;myeloid DC: 7.4;naive B-cell: 7.0;naive CD4 T-cell: 2.9;non-classical monocyte: 10.5;plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "GAMG: 13.0;NTERA-2: 8.2;SCLC-21H: 5.0;SH-SY5Y: 9.9;THP-1: 4.1" "Region enhanced" "Detected in many" "olfactory region: 215.3" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 3.3 1.2 16.2 3.1 26.1 0.6 1.1 1.0 15.3 1.7 10.4 1.5 0.0 2.0 4.5 2.1 0.8 1.2 1.6 0.7 11.3 10.6 21.6 1.6 6.7 3.2 4.8 8.8 0.7 0.6 0.6 3.8 4.4 4.0 0.7 28.5 1.1 0.8 1.1 0.5 0.7 1.9 7.1 2.6 3.6 1.0 0.9 3.5 0.0 0.5 0.0 3.5 1.7 0.5 8.3 9.5 0.0 10.5 0.1 2.9 2.7 0.0 0.1 0.5 0.3 0.5 0.1 0.2 0.0 0.0 0.8 2.0 0.0 0.0 0.3 0.1 0.0 13.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.3 0.1 0.2 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 8.2 1.7 0.0 0.0 0.0 0.0 0.1 0.2 5.0 9.9 1.2 0.0 0.1 0.1 0.1 4.1 0.0 0.1 0.3 0.0 0.3 1.2 0.0 0.4 0.1 0.3 1.5 0.0 5.2 0.0 0.0 10.5 0.0 8.3 1.7 0.4 7.4 7.0 2.9 1.3 0.0 0.1 10.5 9.5 1.3 2.7 16.2 26.1 1.0 15.3 11.3 10.6 4.8 8.8 4.0 3.5 0.0 0.3 4.5 0.8 0.2 16.3 0.6 0.0 0.0 3.4 15.7 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 22.6 23.8 3.5 1.8 17.2 0.0 0.6 9.2 0.0 19.0 2.6 0.3 0.1 3.5 0.4 0.0 4.6 0.0 0.4 0.3 1.0 0.4 0.2 0.0 11.2 0.7 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase, receptor type R" Q15256 12 70638073-70920843 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 56.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 11.2;Club cells: 5.7;Enterocytes: 7.3;Horizontal cells: 15.9;Paneth cells: 11.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 56.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 14.3;RT4: 27.4" "Region enriched" "Detected in all" 5 "cerebellum: 100.5" "Low region specificity" "Detected in all" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" 0.4 3.8 18.8 1.6 11.3 0.3 0.4 56.1 20.9 0.5 11.2 0.1 0.0 5.1 8.4 0.3 0.4 0.5 1.9 0.4 8.6 4.9 0.4 0.4 0.4 0.4 1.3 13.2 0.4 0.6 0.3 0.9 0.7 3.3 0.5 7.8 0.8 0.4 2.1 0.4 0.4 11.3 4.9 3.1 0.4 4.4 0.4 1.4 0.0 0.4 0.0 0.3 4.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 27.4 0.1 4.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.8 11.3 56.1 20.9 8.6 4.9 1.3 13.2 3.3 1.4 0.0 0.0 0.0 0.1 0.5 11.2 2.5 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.1 1.7 1.5 7.3 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 15.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 1.9 11.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.4 0.3 PTPRS ENSG00000105426 "Protein tyrosine phosphatase, receptor type S" Q13332 19 5158495-5340803 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Basal keratinocytes: 54.1;Melanocytes: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 82 "plasmacytoid DC: 13.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 13.4" "Cell line enhanced" "Detected in many" "AN3-CA: 41.4;HaCaT: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 92000000 "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 59.1 17.3 14.4 9.4 14.8 3.1 32.0 27.6 53.3 28.7 11.4 29.6 14.4 4.6 21.4 15.4 13.3 24.0 22.2 18.6 15.9 15.1 10.7 6.9 13.9 8.6 20.5 12.1 29.2 38.4 10.5 16.6 4.3 12.0 23.1 3.6 28.9 21.5 20.1 11.9 23.8 6.5 17.5 13.8 8.3 12.7 10.8 18.7 4.4 21.1 7.2 7.5 19.1 22.7 0.0 13.4 0.0 0.0 0.0 0.1 0.0 3.7 21.3 19.2 41.4 8.8 7.2 2.5 6.4 7.7 7.8 6.4 0.2 2.0 0.0 15.3 10.8 6.2 42.1 5.1 0.0 3.5 0.4 8.2 0.0 8.7 13.2 4.0 0.0 4.8 7.6 1.8 1.6 0.3 10.2 0.2 2.6 5.9 0.0 3.1 15.7 1.6 4.0 10.8 0.1 9.1 0.0 4.2 0.0 1.6 7.5 14.8 20.3 6.1 1.1 11.7 3.9 7.4 1.6 0.9 7.0 12.1 16.0 7.8 2.1 0.0 12.2 3.6 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 14.4 14.8 27.6 17.6 15.9 15.1 20.5 12.1 12.0 18.7 6.0 0.6 3.2 32.4 54.1 33.8 10.9 12.7 1.4 2.3 12.2 2.0 0.5 8.3 1.4 2.3 10.2 0.0 0.0 0.8 23.7 30.9 35.7 0.0 18.3 1.5 11.1 2.9 28.3 0.3 2.9 43.1 1.4 75.9 0.0 0.0 37.3 0.5 0.0 33.9 2.4 7.7 12.9 39.2 7.2 5.3 32.0 0.8 0.0 0.0 21.1 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase, receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.5;fallopian tube: 17.0" "Cell type enhanced" "Detected in some" 17 "Bipolar cells: 40.8;Ciliated cells: 33.5;Early spermatids: 10.0;Late spermatids: 9.9" "Cancer enhanced" "Detected in many" "breast cancer: 5.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.6;RPMI-8226: 1.2;SCLC-21H: 2.9;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved NA NA "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.6 0.8 5.0 0.6 11.1 0.5 4.6 1.6 23.5 1.6 0.7 0.9 0.0 1.2 0.5 1.8 0.5 17.0 0.7 0.8 4.7 6.5 0.6 0.9 2.1 1.0 2.2 12.6 0.5 0.9 0.5 4.1 4.6 5.1 0.8 0.6 0.5 2.0 4.6 0.5 0.8 1.0 0.5 1.4 0.7 1.8 2.8 0.9 4.9 0.5 0.0 1.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 11.1 1.6 22.6 4.7 6.5 2.2 12.6 5.1 0.9 0.0 0.6 0.0 0.0 0.8 40.8 1.1 0.0 33.5 1.2 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 4.8 0.0 7.4 0.3 9.9 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 PTPRU "FMI, hPTP-J, PCP-2, PTP, PTPRO" ENSG00000060656 "Protein tyrosine phosphatase, receptor type U" Q92729 1 29236516-29326813 "Enzymes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Rod photoreceptor cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 40.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB011476, HPA039832" Approved NA NA "CAB011476: AB_442989, HPA039832: AB_10793923" "unprognostic (7.81e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-3)" "unprognostic (6.13e-2)" "prognostic unfavorable (7.92e-4)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.17e-1)" "unprognostic (1.83e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-3)" "unprognostic (3.39e-3)" "unprognostic (6.83e-2)" "unprognostic (1.19e-2)" "unprognostic (6.82e-2)" "unprognostic (4.92e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-1)" 6.0 3.2 3.1 1.7 5.8 0.6 16.0 6.7 12.7 24.8 3.7 2.6 6.1 1.3 9.5 4.7 3.9 14.5 7.0 8.9 4.5 5.1 3.9 7.0 11.4 1.2 5.2 5.3 12.2 12.0 12.1 8.1 14.3 21.4 11.0 2.3 18.7 11.3 17.9 14.7 7.3 1.7 6.5 6.6 2.4 4.5 4.4 0.9 0.3 4.9 2.1 2.0 12.2 17.6 0.4 0.0 0.0 0.5 0.0 0.2 0.0 3.2 4.4 0.2 0.6 12.4 0.4 40.5 3.4 3.1 0.1 0.2 3.8 14.4 0.5 6.9 0.6 0.4 17.5 16.1 11.2 0.0 0.2 8.1 0.6 5.0 16.0 5.2 0.0 0.7 5.7 6.1 0.0 1.0 4.8 0.1 2.0 0.1 0.5 3.2 5.3 0.2 0.1 6.6 6.4 2.0 0.0 4.7 0.2 5.0 16.2 13.7 17.8 3.5 11.0 2.4 2.9 6.5 0.7 2.9 0.6 4.0 1.1 0.4 0.3 0.4 0.0 8.0 0.7 0.8 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.1 5.8 6.7 12.7 4.5 5.1 5.2 5.3 21.4 0.9 8.9 12.8 0.0 6.2 1.3 3.6 3.4 0.0 6.7 11.4 5.2 11.8 16.4 0.0 5.6 0.5 0.7 0.0 0.0 2.3 9.3 5.1 5.4 1.1 4.5 2.1 0.0 0.0 1.8 1.2 1.1 4.4 0.3 8.5 0.0 0.0 17.4 5.3 0.0 6.7 0.2 40.7 6.5 3.8 1.2 6.1 0.5 7.6 0.0 0.0 8.6 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase, receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 118.1" "Cell type enhanced" "Detected in some" 17 "Club cells: 27.3;Horizontal cells: 62.0;Muller glia cells: 107.0" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 94.3;NTERA-2: 26.3;WM-115: 41.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 950000 Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 2.0 2.5 33.1 2.3 44.1 1.5 4.0 15.4 118.1 2.4 2.2 19.3 0.0 1.9 1.6 2.0 7.0 1.7 1.9 2.0 39.6 15.9 1.6 1.6 2.1 1.5 18.6 17.8 2.0 3.3 1.5 1.6 1.6 67.6 2.1 2.3 0.8 2.4 2.0 1.5 19.3 1.9 2.4 76.6 2.1 9.8 1.7 23.6 0.0 1.5 1.8 3.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 1.1 0.0 0.1 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 44.1 15.4 39.6 39.6 15.9 18.6 17.8 67.6 23.6 0.0 1.0 0.0 5.6 22.3 14.1 0.8 0.0 17.4 27.3 0.0 3.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 1.1 1.1 0.0 0.0 0.1 62.0 0.0 0.0 0.0 0.4 0.3 0.0 18.6 0.0 0.0 107.0 0.6 0.0 0.0 0.0 6.2 0.0 0.4 0.0 0.2 18.7 0.2 0.0 0.0 7.4 PTRH1 "C9orf115, PTH1" ENSG00000187024 "Peptidyl-tRNA hydrolase 1 homolog" Q86Y79 9 127690348-127724873 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021223 Uncertain NA NA "HPA021223: AB_1845798" "unprognostic (6.58e-2)" "unprognostic (7.01e-3)" "unprognostic (3.46e-3)" "unprognostic (2.53e-2)" "unprognostic (7.05e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (3.90e-2)" "unprognostic (1.74e-1)" "unprognostic (6.58e-3)" "unprognostic (8.67e-2)" "unprognostic (4.08e-2)" "unprognostic (5.98e-3)" "unprognostic (5.74e-4)" "unprognostic (1.38e-2)" "unprognostic (1.91e-1)" "unprognostic (1.72e-2)" 14.9 15.0 12.5 8.3 11.9 7.1 9.1 3.9 13.7 9.4 7.8 10.7 12.9 7.7 7.8 16.1 7.8 9.9 12.6 13.1 10.7 9.4 14.5 19.3 7.5 14.7 11.6 8.5 6.2 24.7 8.8 11.0 7.2 8.9 9.9 4.0 8.3 9.3 9.9 13.0 15.1 5.8 6.4 6.2 9.4 12.4 16.1 6.2 7.1 18.8 9.1 5.7 9.4 5.6 8.7 11.4 5.6 14.4 10.5 29.4 12.8 15.9 7.1 1.6 4.4 2.3 3.0 12.5 10.6 2.9 4.1 2.2 3.7 6.0 6.0 14.3 4.4 5.5 17.6 1.3 7.7 1.2 8.7 2.4 2.6 8.9 7.1 6.9 3.9 7.2 2.5 8.0 4.9 5.1 2.2 8.1 8.4 6.8 4.8 4.6 14.7 7.0 5.8 2.2 14.6 32.3 6.1 3.5 13.6 7.4 3.5 7.1 6.5 11.4 13.7 8.0 1.5 12.3 2.5 9.6 5.9 8.2 20.9 6.6 14.4 7.7 3.9 7.9 3.0 7.1 2.5 13.2 5.6 29.3 14.4 29.3 8.7 15.1 29.4 11.4 7.2 11.1 25.5 1.7 10.5 7.5 10.4 14.2 12.8 12.5 11.9 3.9 13.7 10.7 9.4 11.6 8.5 8.9 6.2 3.0 7.8 12.4 33.6 15.0 22.3 0.3 25.5 46.8 6.8 45.4 43.2 11.0 56.3 56.3 53.7 19.7 8.1 0.0 29.3 19.6 18.8 39.9 17.3 25.2 41.1 15.9 28.9 19.0 9.1 11.4 20.4 13.7 15.1 17.2 19.3 20.7 39.4 10.4 88.4 101.3 60.3 0.0 21.5 27.4 7.9 18.4 15.7 20.3 16.6 30.8 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 15.9 22.9 17.1 12.4 17.1 9.9 20.7 12.5 22.1 15.6 17.2 11.8 16.3 11.6 14.3 36.7 16.4 13.8 13.1 12.6 19.3 17.8 14.8 34.7 12.1 12.5 16.7 15.2 14.2 19.9 10.3 18.3 13.6 21.0 15.9 20.7 8.1 13.7 18.7 23.3 11.4 11.0 16.8 17.1 15.5 14.3 15.7 18.1 9.0 11.8 13.5 16.9 13.0 10.5 15.6 21.6 12.6 29.3 13.1 15.5 13.0 18.9 36.2 11.7 10.6 22.2 19.1 12.5 18.3 16.1 15.7 23.0 23.4 14.9 13.8 27.8 15.3 26.9 18.9 25.1 23.6 22.9 26.5 34.1 24.6 18.8 42.8 34.3 21.7 14.0 21.5 30.7 24.3 28.3 11.2 26.1 9.7 27.4 15.4 23.3 45.8 18.5 17.7 10.0 49.3 28.7 10.1 19.6 20.1 26.1 27.3 15.1 19.6 9.4 10.3 22.4 14.0 24.1 15.5 17.1 20.5 20.7 12.2 19.8 20.0 22.2 20.4 13.5 13.6 15.6 1.9 25.8 1.1 9.2 24.4 12.4 15.6 10.8 10.4 18.5 13.1 15.5 11.1 12.6 13.1 29.3 21.6 12.3 13.0 17.1 17.1 12.5 22.1 19.3 17.8 16.7 15.2 21.0 18.1 14.9 12.8 13.4 31.9 32.5 3.3 14.8 7.6 30.8 50.0 10.4 3.9 22.1 10.0 25.9 17.7 18.3 9.1 0.0 22.0 20.6 19.7 23.3 22.0 27.3 15.2 7.9 6.4 11.6 7.3 7.9 16.1 18.7 13.5 10.0 9.7 6.6 25.9 13.9 9.2 13.2 3.2 12.9 21.7 16.7 11.4 31.1 26.5 8.3 13.2 31.5 PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789734-24793382 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm NA NA 55000 Nucleoplasm "HPA019951: AB_1853109" "unprognostic (1.28e-2)" "unprognostic (5.79e-2)" "unprognostic (6.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-2)" "unprognostic (3.99e-1)" "unprognostic (8.84e-3)" "unprognostic (1.26e-1)" "unprognostic (3.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (5.76e-2)" 8.2 20.0 19.4 10.8 16.2 20.4 13.3 4.6 13.0 6.7 13.6 8.5 7.8 16.1 5.6 11.9 12.7 8.2 10.2 15.8 15.6 14.4 11.3 16.0 9.2 17.6 16.9 8.8 8.5 28.1 2.7 8.4 12.2 10.4 11.0 9.4 7.6 25.9 7.5 30.1 10.3 15.0 5.6 15.5 10.4 11.7 25.2 6.9 17.5 15.6 19.9 12.9 8.3 8.4 29.1 44.1 8.2 27.9 14.5 23.7 26.1 8.2 19.7 6.4 2.8 3.6 8.1 11.0 6.0 5.7 7.9 5.1 19.4 7.8 6.9 2.5 6.4 4.9 5.5 5.3 5.6 2.6 9.3 35.5 12.4 9.5 21.1 7.5 10.1 11.7 7.7 4.6 3.7 4.1 6.3 7.3 6.3 12.4 5.5 5.8 17.9 8.3 18.9 13.4 5.0 11.9 6.8 19.5 11.4 9.2 15.4 10.0 15.4 6.6 8.9 7.7 3.1 8.6 7.8 12.0 6.7 10.5 3.2 5.0 4.3 13.3 7.4 6.3 6.4 4.5 8.2 27.9 5.9 16.6 19.0 8.5 29.1 16.4 14.5 42.9 22.1 15.3 17.8 3.2 14.5 13.7 44.1 23.7 26.1 19.4 16.2 4.6 13.0 15.6 14.4 16.9 8.8 10.4 6.9 47.6 55.7 79.8 66.2 106.5 9.2 71.1 66.2 88.3 51.2 62.8 5.9 158.8 97.8 80.3 89.5 45.2 101.8 0.0 123.7 124.1 73.0 66.7 40.4 82.2 114.7 1.6 84.6 51.0 98.7 121.2 43.7 98.5 64.1 162.3 129.2 35.2 108.6 131.0 37.4 119.9 11.8 71.1 48.3 75.3 38.1 124.0 140.3 64.8 148.8 111.1 PUDP "DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A" ENSG00000130021 "Pseudouridine 5'-phosphatase" Q08623 X 7048920-7148190 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cytotrophoblasts: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA072672 Approved NA NA 14000 "HPA072672: AB_2732208" "unprognostic (1.84e-1)" "unprognostic (4.93e-2)" "unprognostic (5.15e-3)" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (5.63e-3)" "unprognostic (1.00e-3)" "unprognostic (3.22e-2)" "unprognostic (4.86e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (7.27e-4)" "unprognostic (2.24e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-1)" "unprognostic (2.92e-2)" "prognostic favorable (4.80e-4)" "unprognostic (3.42e-2)" 10.8 9.3 10.2 10.3 12.5 2.6 7.5 7.8 10.5 9.1 15.0 9.7 9.1 15.2 8.6 6.3 9.9 17.0 7.1 17.1 8.1 10.6 19.8 10.1 10.3 13.1 12.5 7.1 9.6 8.9 7.3 11.2 42.4 10.0 7.4 10.5 8.3 9.8 6.9 31.8 5.0 15.1 9.8 10.6 11.2 15.8 7.7 11.4 13.3 10.4 8.9 13.1 10.2 8.9 7.0 11.1 2.1 14.9 5.1 9.6 7.5 19.5 18.4 29.1 12.1 14.9 14.7 5.0 7.0 6.7 7.7 7.9 26.1 12.1 9.0 14.5 6.9 26.5 6.0 13.2 15.6 12.0 8.0 25.5 9.5 6.9 14.3 7.1 8.3 10.8 7.7 6.1 21.0 9.8 5.4 23.1 11.5 18.2 8.2 12.2 9.1 9.3 12.3 15.4 8.1 9.1 7.0 11.3 24.3 11.2 7.4 7.0 7.3 5.5 10.4 10.4 26.4 11.6 7.8 8.9 4.8 2.9 19.9 5.9 26.2 0.1 14.6 6.8 4.8 9.3 2.1 14.4 1.6 6.4 14.9 6.4 7.0 6.8 6.0 11.1 5.2 5.2 5.8 1.5 5.1 14.0 3.6 9.6 7.5 10.2 12.5 7.8 10.5 8.1 10.6 12.5 7.1 10.0 11.4 11.9 2.9 10.4 3.2 0.0 3.6 0.0 22.9 9.4 6.8 17.4 3.9 36.7 8.3 18.0 0.4 3.6 8.4 0.0 15.2 25.6 2.0 5.5 1.1 9.0 19.6 4.8 0.0 4.3 19.2 1.0 5.8 6.8 0.0 7.2 15.3 12.6 14.7 28.1 4.6 19.5 4.3 6.5 0.0 5.1 17.0 0.0 23.6 0.0 15.5 5.5 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905264-34918989 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Approved Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA006692: AB_2667645" "prognostic unfavorable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.1 6.5 3.4 3.2 4.9 4.8 4.4 5.2 4.7 5.4 3.2 2.9 4.6 3.8 3.7 3.5 3.3 6.6 3.5 4.4 3.7 3.5 5.6 6.1 2.9 4.0 3.3 3.0 3.4 6.0 5.3 3.1 4.3 3.7 7.4 4.5 3.6 3.3 2.6 3.1 3.7 5.8 5.2 4.7 3.8 4.7 9.4 7.6 7.2 3.1 4.8 9.3 2.6 5.8 6.8 7.3 14.0 5.1 6.0 10.4 9.2 9.0 9.7 8.0 6.4 8.0 15.2 3.3 8.2 11.7 5.4 8.0 5.6 10.9 6.8 6.8 8.1 20.7 4.4 8.8 11.1 7.5 5.3 4.8 10.6 7.1 3.6 4.7 6.6 14.4 9.1 8.2 7.3 11.3 7.9 9.5 3.8 10.3 10.4 15.2 5.3 4.7 6.2 7.5 7.9 19.0 13.0 8.5 5.3 8.0 9.3 4.2 12.7 9.7 6.5 9.6 5.0 9.1 13.4 6.6 16.8 8.8 7.2 3.0 6.8 5.9 3.1 7.7 8.7 6.5 8.0 2.9 9.4 9.3 8.0 2.3 4.8 2.9 7.6 5.3 2.6 20.8 39.2 16.0 18.1 26.0 22.1 20.7 15.3 9.4 13.6 19.2 25.5 69.8 16.6 14.1 15.1 14.1 9.5 23.3 19.5 44.4 23.7 18.0 20.8 12.1 20.7 22.3 12.6 9.2 13.2 11.8 23.3 15.3 16.9 10.0 11.0 18.9 14.2 10.5 20.5 13.2 33.2 12.9 19.1 59.4 59.0 25.0 67.4 26.3 11.2 19.7 RAD54L2 "ARIP4, KIAA0809, SRISNF2L" ENSG00000164080 "RAD54 like 2" Q9Y4B4 3 51541144-51668667 "Enzymes, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035004, HPA039992, HPA077351" Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA035004: AB_10671930, HPA039992: AB_2676789, HPA077351: " "unprognostic (1.46e-2)" "unprognostic (3.67e-2)" "unprognostic (2.61e-1)" "unprognostic (5.01e-2)" "unprognostic (1.15e-1)" "unprognostic (4.38e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-2)" "unprognostic (9.24e-2)" "unprognostic (2.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.71e-5)" "unprognostic (3.72e-2)" "unprognostic (3.19e-1)" "unprognostic (3.30e-2)" "unprognostic (6.63e-2)" 4.4 4.1 3.3 3.5 4.3 5.2 4.1 7.8 4.3 3.6 4.4 2.2 5.3 4.6 3.6 3.9 2.5 3.1 3.4 3.5 3.4 8.8 4.2 3.8 3.4 5.6 5.0 5.3 3.9 4.9 3.8 3.5 3.7 4.2 7.3 4.6 4.1 4.3 4.1 4.7 4.4 4.7 4.2 5.2 3.8 3.5 6.9 5.2 6.5 7.1 6.3 8.3 4.0 5.6 4.4 11.4 11.2 6.4 4.6 6.0 4.8 6.8 6.6 6.3 7.8 3.3 14.8 1.4 8.4 6.9 4.4 17.9 6.0 8.2 7.8 4.0 12.7 9.5 5.1 5.8 14.1 7.6 5.2 4.8 10.1 9.8 4.2 7.3 12.9 8.3 8.1 5.2 4.3 12.6 6.4 9.0 2.8 4.8 5.8 8.8 2.0 3.3 7.3 4.7 8.9 7.6 7.3 4.9 7.2 4.7 8.5 9.5 7.0 8.0 7.1 9.3 8.7 8.8 15.0 7.5 8.0 8.8 6.5 4.8 4.7 8.1 6.0 8.3 4.3 7.1 6.6 5.2 6.9 4.7 5.4 2.2 6.3 7.1 5.2 6.3 4.0 8.9 11.8 9.0 6.6 8.1 33.3 9.7 10.2 10.7 7.9 8.7 29.5 13.5 1.7 8.3 6.1 11.1 4.2 0.0 9.0 7.3 8.0 8.9 17.4 20.7 7.7 44.5 15.6 11.1 11.4 1.9 14.1 6.8 13.5 4.6 6.8 10.4 10.2 6.2 15.9 3.4 31.5 12.9 9.2 37.2 39.4 7.9 24.8 9.6 7.0 9.8 RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006725, HPA048155" Enhanced Supported Nucleoplasm NA NA Nucleoplasm "HPA006725: AB_1856041, HPA048155: AB_2680290" "unprognostic (7.64e-2)" "prognostic favorable (6.95e-4)" "unprognostic (8.83e-3)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (2.12e-3)" "unprognostic (9.64e-3)" "unprognostic (1.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (9.19e-2)" "unprognostic (2.50e-2)" "prognostic unfavorable (2.82e-5)" "unprognostic (6.16e-2)" "unprognostic (3.72e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.52e-6)" 5.4 5.2 7.0 10.6 8.4 10.8 6.1 7.7 6.3 6.7 11.8 8.5 5.1 14.2 7.1 4.1 8.2 12.1 6.3 6.1 3.8 3.5 6.9 9.4 9.5 9.0 7.8 2.5 6.8 20.1 3.7 7.2 10.2 5.5 8.6 3.3 4.9 12.8 8.1 7.8 12.8 17.5 5.5 4.1 10.7 11.3 7.2 6.0 18.2 11.7 7.2 16.8 6.2 7.1 6.7 5.1 8.9 3.9 4.7 9.0 3.2 6.7 11.0 5.8 8.3 1.7 0.8 7.8 4.3 2.9 5.0 4.3 13.1 12.9 8.1 8.1 0.9 7.9 11.4 3.4 3.3 0.7 7.7 9.5 10.9 5.9 6.5 2.4 7.1 14.4 2.1 3.3 4.3 1.8 3.1 3.3 15.3 8.8 9.0 1.0 20.9 13.8 13.8 8.8 9.4 8.3 11.5 7.9 9.2 1.3 5.4 6.7 7.2 6.0 16.4 13.6 1.3 11.6 6.8 2.5 7.2 9.4 14.6 5.1 9.6 8.9 7.0 4.8 7.0 5.9 8.0 3.2 8.9 9.0 3.6 6.4 6.7 7.2 7.3 2.1 5.3 4.9 5.7 4.7 4.7 3.9 5.1 3.9 3.2 7.0 8.4 7.7 6.3 3.8 3.5 7.8 2.5 5.5 6.0 20.8 17.9 32.3 16.6 15.1 18.1 0.8 12.7 29.4 23.9 19.2 66.8 21.0 11.6 10.1 18.0 13.7 57.3 0.0 11.5 18.5 14.7 20.0 19.7 5.9 13.4 20.6 13.7 8.6 7.1 9.4 9.8 22.6 18.6 4.6 18.9 14.0 9.0 24.6 11.7 6.9 31.2 12.9 9.7 27.6 15.0 15.2 34.0 41.5 24.0 11.9 RECQL "RecQ1, RecQL1" ENSG00000004700 "RecQ like helicase" P46063 12 21468911-21501669 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009743, HPA030960, HPA064259" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "CAB009743: AB_655306, HPA030960: AB_10794912, HPA064259: AB_2685230" "unprognostic (9.70e-3)" "unprognostic (2.55e-2)" "unprognostic (1.86e-2)" "unprognostic (6.25e-3)" "unprognostic (2.47e-1)" "unprognostic (1.39e-1)" "unprognostic (8.97e-3)" "unprognostic (1.89e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (3.15e-4)" "unprognostic (3.77e-3)" "unprognostic (3.78e-2)" "unprognostic (2.85e-1)" "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (2.99e-1)" "unprognostic (3.69e-2)" 32.7 15.8 10.0 22.0 12.7 10.8 18.2 10.9 11.2 18.0 16.3 9.4 11.0 7.5 19.8 14.4 18.7 14.6 14.1 17.9 11.2 7.2 19.6 18.0 19.5 25.7 15.3 7.6 16.0 11.9 8.0 14.8 17.1 12.0 14.0 12.7 6.7 13.1 12.4 15.0 12.4 15.5 20.5 19.5 34.0 12.9 10.8 13.0 27.4 17.4 14.3 25.0 22.6 13.0 19.3 15.2 11.3 20.7 23.1 28.0 13.8 17.2 17.5 13.3 9.8 26.9 33.8 15.4 33.3 28.2 21.5 25.2 19.1 14.4 20.7 12.9 22.7 27.3 12.6 14.2 16.6 30.7 34.6 9.4 25.3 19.4 8.1 10.4 17.5 19.1 18.8 8.6 30.5 22.4 19.8 24.1 14.6 8.8 10.1 28.3 8.4 19.1 20.4 22.1 5.3 11.9 15.8 53.9 16.0 8.3 11.9 3.6 10.6 24.9 6.7 17.5 48.0 17.0 11.2 32.5 30.3 19.7 26.5 30.9 4.1 12.2 45.4 25.6 10.3 22.2 9.3 11.8 11.3 21.9 20.7 21.3 19.3 20.5 21.0 15.2 16.0 13.6 18.8 5.5 23.1 18.8 11.6 28.0 13.8 10.0 12.7 10.9 11.2 11.2 7.2 15.3 7.6 12.0 13.0 20.8 19.7 38.7 12.7 20.9 10.9 7.3 12.7 30.8 25.0 14.0 13.7 9.7 8.3 16.8 0.5 36.0 3.2 0.0 21.6 23.8 30.7 7.0 50.8 11.9 25.0 14.3 9.4 28.3 30.7 2.0 20.4 35.9 28.7 49.5 6.0 17.7 24.4 5.5 35.3 9.5 10.9 12.9 25.8 6.0 8.1 37.5 3.0 41.7 6.9 8.2 RECQL5 "FLJ90603, RecQ5" ENSG00000108469 "RecQ like helicase 5" O94762 17 75626845-75667189 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Collecting duct cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029971 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA029971: AB_10611389" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "prognostic unfavorable (1.73e-6)" "unprognostic (8.39e-2)" "unprognostic (2.34e-2)" "unprognostic (3.57e-3)" "unprognostic (5.83e-2)" "unprognostic (3.15e-1)" "unprognostic (5.84e-2)" "prognostic favorable (4.34e-4)" "unprognostic (4.07e-2)" "unprognostic (7.01e-2)" "unprognostic (6.37e-2)" "unprognostic (1.42e-1)" "unprognostic (4.78e-1)" "unprognostic (1.81e-2)" 7.4 12.9 12.6 11.7 16.0 10.0 9.8 11.4 17.7 9.4 10.6 24.4 17.4 22.9 10.5 13.2 20.4 11.8 12.4 6.7 12.9 8.6 14.9 15.8 8.4 16.8 14.5 11.0 14.3 10.8 17.6 21.9 32.3 14.3 12.2 9.8 13.2 15.6 14.0 6.8 21.1 23.2 9.6 13.2 16.6 23.8 21.0 17.0 12.1 21.4 6.2 16.0 12.1 12.8 5.2 16.4 6.0 3.9 3.8 4.2 3.2 11.2 20.9 8.5 12.0 11.8 7.9 19.6 8.3 7.0 10.9 9.7 9.2 12.0 13.4 9.1 7.3 14.5 10.8 8.8 10.0 10.4 7.2 16.4 24.4 25.3 13.2 11.9 7.9 12.2 11.2 12.3 10.8 13.1 12.5 14.2 14.9 12.3 11.9 8.0 10.0 16.1 10.7 5.5 10.8 16.2 13.1 19.8 13.5 9.2 13.4 10.2 9.9 9.1 16.4 11.2 12.2 29.5 6.3 7.2 14.1 16.2 7.7 8.6 17.0 9.7 12.9 11.6 7.9 10.1 6.0 3.1 4.4 4.2 3.9 2.7 3.6 2.7 3.1 3.8 5.2 4.1 2.9 2.1 3.8 1.9 16.4 2.2 3.2 12.6 16.0 11.4 17.7 12.9 8.6 14.5 11.0 14.3 17.0 0.0 9.9 5.4 2.9 0.9 7.9 6.1 5.1 14.7 2.3 26.2 17.7 6.8 5.0 4.6 3.7 3.6 11.1 0.0 2.9 4.2 3.1 2.9 1.1 6.0 4.4 9.5 4.6 8.0 5.9 1.5 3.7 3.9 3.3 1.8 8.5 7.4 5.3 8.2 2.5 3.7 12.8 0.0 1.0 10.9 10.5 1.8 9.7 4.4 6.3 8.9 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 63.6" "Group enriched" "Detected in some" 5 "Early spermatids: 6.1;Late spermatids: 19.3" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Region enriched" "Detected in single" 12 "basal ganglia: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.4;BJ: 4.9;HMC-1: 6.5;RT4: 1.8;SK-BR-3: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005131 Approved "Secreted to blood" NA NA 692000 "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 0.0 1.2 0.0 0.5 0.0 0.0 3.1 0.2 0.0 0.8 0.1 4.4 13.5 0.1 0.3 0.0 0.6 0.0 0.0 63.6 0.4 0.3 0.0 0.0 0.0 11.6 0.0 0.0 0.4 14.4 0.0 0.3 0.1 0.4 0.3 0.5 0.0 0.0 0.1 1.0 0.0 0.0 0.0 2.0 0.0 0.0 1.1 0.0 0.2 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.9 1.0 0.0 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 6.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.2 0.6 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 4.6 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 1.2 6.1 0.0 0.0 0.0 1.0 0.2 0.1 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.4 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 2.7 RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 51.0;liver: 118.8" "Cell type enhanced" "Detected in many" 13 "Distal tubular cells: 49.7;Hepatocytes: 141.5;Muller glia cells: 48.0;Peritubular cells: 65.4;Proximal tubular cells: 86.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 16.5;fHDF/TERT166: 5.3;Hep G2: 24.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103, HPA029104" Enhanced Approved Cytosol NA NA 47000 Cytosol "HPA029102: AB_10599846, HPA029103: AB_10602097, HPA029104: " "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favorable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favorable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" 2.6 51.0 6.7 0.6 6.5 0.4 1.5 8.4 6.2 2.8 1.9 6.2 2.5 4.5 2.3 6.1 1.5 1.7 2.0 4.5 6.1 4.2 17.6 118.8 4.9 0.7 5.9 4.5 7.5 12.7 6.2 2.5 4.2 5.0 4.8 1.1 8.4 7.5 6.3 3.8 0.6 4.6 4.9 4.4 1.1 2.9 1.5 5.2 0.0 6.5 1.6 0.6 2.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.3 0.6 0.0 0.0 16.5 0.0 0.0 0.9 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.6 0.8 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.7 6.5 8.4 6.2 6.1 4.2 5.9 4.5 5.0 5.2 6.0 2.2 0.0 2.9 0.5 10.2 25.8 7.6 2.7 1.2 14.0 0.0 0.1 49.7 8.4 0.4 1.8 0.0 0.0 7.9 0.1 7.5 0.9 0.0 141.5 0.1 4.8 4.6 6.2 4.0 0.6 23.0 0.0 1.7 0.0 0.0 48.0 7.8 0.0 65.4 86.9 1.9 12.9 8.0 0.2 0.2 0.3 0.2 0.0 0.3 1.1 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 35.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: AB_2683343" "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 12.7 14.8 10.8 16.7 16.0 11.0 13.6 8.3 13.0 13.8 14.3 21.2 9.4 11.0 20.6 16.3 13.6 15.4 12.4 14.5 11.4 9.0 13.6 16.9 12.6 17.7 17.6 11.0 18.8 20.4 18.6 17.1 10.5 13.0 15.7 12.4 13.1 14.3 15.5 13.9 13.0 17.5 15.6 16.5 17.3 13.2 25.6 14.7 56.6 17.3 8.8 18.9 18.7 15.4 19.9 16.6 9.8 15.5 8.8 12.5 8.5 5.2 4.5 4.8 7.4 14.6 14.6 0.0 12.5 10.0 6.2 7.1 3.9 9.1 4.9 10.4 12.6 9.0 6.1 0.0 13.0 11.8 12.5 5.0 7.2 2.9 3.4 15.7 7.6 4.2 13.6 19.0 11.8 25.7 7.2 4.7 13.0 19.3 12.9 6.4 10.0 12.9 3.9 0.0 6.1 4.8 5.6 0.0 7.1 5.0 6.3 4.7 3.6 6.8 2.4 9.2 9.5 6.9 8.8 6.2 2.8 6.3 10.7 3.5 14.4 6.7 35.4 9.1 9.3 8.2 8.1 11.1 9.8 6.1 15.5 9.7 17.3 9.6 7.5 13.7 19.9 10.8 8.9 2.5 8.8 10.3 16.6 12.5 8.5 10.8 16.0 8.3 13.0 11.4 9.0 17.6 11.0 13.0 14.7 11.9 5.4 22.9 7.2 4.6 6.3 14.0 2.5 4.0 7.9 10.4 15.7 6.0 3.3 6.1 12.7 5.8 5.0 0.0 8.0 3.3 5.2 9.4 8.1 11.3 4.6 11.1 1.7 3.1 9.2 13.7 5.2 5.0 11.8 1.8 7.1 9.3 7.2 0.0 6.3 2.9 5.9 0.0 7.2 12.9 7.1 4.8 4.7 6.5 3.7 7.7 RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675666-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.3" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 12.0;Cone photoreceptor cells: 11.8;Horizontal cells: 14.3;Rod photoreceptor cells: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD4 T-cell: 3.4" "Group enriched" "Detected in many" 20 "B-cells: 2.2;NK-cells: 1.3;T-cells: 3.4" "Cell line enhanced" "Detected in many" "HeLa: 9.3;MCF7: 9.8;U-266/70: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm No No Nucleoplasm "HPA030359: AB_2673445, HPA030360: AB_2673446, HPA046593: AB_2679711" "prognostic favorable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" 1.7 6.3 10.0 1.1 8.3 2.3 0.7 21.3 14.5 1.3 2.2 1.3 2.2 5.8 1.3 1.7 1.1 1.0 1.2 2.4 8.4 9.9 3.9 1.2 0.8 1.1 5.5 7.2 0.9 6.2 2.2 4.4 1.1 4.6 1.5 1.1 1.5 6.1 2.6 0.8 3.1 5.9 0.7 2.2 0.6 4.5 2.2 1.9 0.7 0.6 0.6 0.5 0.8 0.5 2.2 0.1 0.0 0.0 1.3 3.4 0.7 1.8 2.3 1.3 2.0 1.0 2.7 6.9 0.8 1.3 0.4 0.1 4.8 1.3 0.7 1.6 0.5 0.2 1.2 0.1 0.4 0.0 1.7 8.7 1.0 9.3 1.9 1.0 1.7 1.3 1.8 3.3 0.3 0.0 1.0 0.1 3.1 1.3 1.3 0.1 9.8 0.4 4.7 1.3 2.5 0.7 8.3 1.2 1.8 0.1 1.6 1.7 2.3 1.0 0.5 2.2 0.9 3.6 4.9 0.5 2.8 2.6 0.9 0.6 11.9 1.6 2.3 1.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 0.3 0.0 0.5 0.5 0.2 0.0 1.3 0.0 0.1 1.2 0.7 10.0 8.3 21.3 14.5 8.4 9.9 5.5 7.2 4.6 1.9 0.0 0.0 0.0 4.2 1.9 12.0 0.8 0.0 8.1 1.2 0.0 11.8 0.2 0.0 0.7 2.0 0.0 3.9 0.0 0.5 0.2 0.9 1.4 0.0 0.8 0.3 14.3 2.4 0.6 1.2 1.1 1.4 0.0 0.0 0.0 4.5 2.0 1.0 3.6 2.5 7.4 35.2 0.0 0.5 0.7 2.1 1.6 0.2 0.0 4.7 1.6 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941799 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.9" "Cell type enhanced" "Detected in many" 6 "Enterocytes: 26.3;Pancreatic endocrine cells: 31.9;Suprabasal keratinocytes: 24.8;Undifferentiated cells: 31.4;Urothelial cells: 36.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 8.2;CAPAN-2: 26.6;HaCaT: 13.8;RT4: 26.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 1.4 0.0 2.9 6.7 2.7 0.0 1.5 0.4 4.0 5.5 14.9 1.7 0.4 0.7 1.9 0.7 18.9 0.7 6.9 4.9 4.2 2.1 0.5 0.4 2.1 1.5 4.9 0.7 1.2 2.4 0.0 0.4 1.0 1.6 3.1 14.7 0.8 8.2 0.4 0.4 13.4 0.9 0.9 7.9 0.6 12.3 8.4 0.4 1.3 0.4 12.2 16.4 6.9 8.2 1.7 2.1 5.3 1.7 0.9 0.9 0.7 8.2 3.3 0.2 0.1 0.1 1.0 0.9 0.4 0.1 0.6 0.1 0.5 26.6 0.2 1.9 3.8 2.4 13.8 0.0 4.9 0.3 0.1 0.1 0.1 2.0 1.8 0.5 0.0 0.3 0.6 0.6 4.0 0.0 2.5 0.8 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.2 0.9 0.7 0.1 0.1 0.0 0.0 26.8 0.2 0.1 2.8 6.8 0.2 0.3 3.5 0.2 0.5 3.0 0.3 0.2 0.2 0.2 0.3 0.3 2.6 0.4 0.1 3.6 1.7 1.1 0.8 1.1 0.4 1.7 0.6 0.5 1.9 1.1 0.7 0.7 5.3 0.9 0.7 2.1 0.9 0.7 2.9 2.7 0.4 1.5 4.2 2.1 4.9 0.7 1.6 0.4 0.0 0.3 0.0 6.7 15.8 2.4 0.4 2.5 9.4 6.8 3.5 0.0 0.4 0.0 11.2 2.8 1.1 26.3 0.0 14.2 0.2 2.3 11.4 4.6 0.0 0.2 1.6 2.4 1.3 0.0 0.4 0.6 0.0 1.7 1.0 21.0 1.5 31.9 23.0 0.0 0.0 1.6 6.5 2.0 0.0 0.0 24.8 0.6 0.0 31.4 36.7 RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32266176-32324661 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7" "Group enriched" "Detected in some" 9 "Horizontal cells: 96.9;Rod photoreceptor cells: 33.8" "Cancer enhanced" "Detected in some" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 5.9;GAMG: 6.8;HDLM-2: 8.0;NTERA-2: 8.7;U-2 OS: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059607 Uncertain NA NA "HPA059607: AB_2684081" "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" 1.0 8.2 6.8 1.2 7.4 0.7 1.1 11.3 23.7 1.4 1.2 2.9 3.3 0.9 2.0 1.9 1.3 4.4 0.9 9.7 10.1 6.6 0.8 0.6 0.7 0.7 9.1 4.6 3.4 1.1 0.6 1.9 1.0 6.7 2.1 1.4 3.9 1.0 5.6 0.6 0.9 0.9 1.8 3.6 0.6 0.9 2.5 4.0 0.0 0.6 0.0 0.8 1.9 1.1 0.8 0.0 0.0 0.0 0.0 0.3 0.3 0.0 5.9 5.9 4.6 0.9 0.0 0.1 0.3 0.6 1.9 1.9 0.1 0.0 0.0 0.4 0.7 6.8 0.1 1.6 0.0 0.5 8.0 2.3 1.0 4.0 0.3 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.3 0.0 0.3 0.5 0.0 0.5 0.1 0.2 0.0 8.7 0.0 0.0 1.0 0.0 0.0 0.0 3.2 0.1 1.5 0.8 0.1 0.1 2.2 0.4 0.1 0.0 0.0 6.1 0.2 2.9 0.0 0.0 0.0 0.3 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 6.8 7.4 11.3 15.6 10.1 6.6 9.1 4.6 6.7 4.0 0.0 0.0 0.0 0.6 0.3 6.0 4.3 0.0 0.0 0.0 0.0 5.9 1.3 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.4 96.9 0.0 0.6 0.8 1.5 0.9 0.0 0.0 0.0 0.1 7.3 0.0 0.0 0.0 0.0 33.8 0.0 1.0 0.0 0.9 0.1 0.5 0.0 0.0 0.5 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "kidney: 81.4;liver: 248.6" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1135.9" "Cancer enhanced" "Detected in all" "liver cancer: 162.2" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5700000 "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 8.3 9.4 16.8 2.5 18.8 1.6 4.2 5.6 11.6 2.6 4.7 4.5 2.7 5.8 2.1 4.8 2.8 2.2 4.3 5.2 11.7 12.5 81.4 248.6 2.2 2.1 19.1 9.5 4.6 5.2 3.5 1.8 2.4 11.8 4.0 4.8 2.3 3.2 2.7 6.8 2.3 4.2 2.5 7.9 1.8 4.6 3.3 9.5 0.6 3.2 3.5 2.6 3.2 1.8 12.1 10.0 5.0 8.3 8.4 12.8 7.1 13.9 12.1 9.8 11.9 22.2 17.3 10.7 12.9 9.1 8.6 10.4 16.4 9.4 19.8 16.6 9.4 11.5 9.9 21.4 18.3 17.5 6.9 9.2 14.4 8.2 17.5 10.1 5.3 2.3 14.9 6.3 12.1 13.3 10.9 11.1 21.4 25.6 4.3 11.5 18.1 11.2 14.4 15.5 61.2 22.1 13.0 7.1 5.7 20.8 10.0 10.6 5.3 8.2 5.7 8.9 13.0 14.5 7.0 6.7 6.7 4.2 11.3 5.1 10.3 14.1 9.7 11.7 11.2 4.3 0.1 8.3 5.0 6.5 7.0 8.3 12.1 9.4 9.5 10.0 9.5 12.2 12.8 1.5 8.4 7.0 7.6 12.3 7.1 16.8 18.8 5.6 11.6 11.7 12.5 19.1 9.5 11.8 9.5 23.8 15.3 0.0 0.0 0.0 0.0 0.0 0.0 10.7 3.4 45.4 0.0 25.5 242.1 13.4 0.0 0.0 0.0 0.0 7.5 23.7 0.0 0.0 2.3 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 10.0 0.0 0.0 14.6 0.0 0.0 1135.9 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20803278 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "pancreas: 809.6" "Cell type enhanced" "Detected in many" 10 "Alveolar cells type 1: 863.6;Alveolar cells type 2: 748.9;Hofbauer cells: 1257.5;Ito cells: 532.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 8.0;myeloid DC: 16.1" "Group enriched" "Detected in many" 9 "dendritic cells: 16.1;monocytes: 8.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 74.4;OE19: 16.9;RT4: 29.1;TIME: 38.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1500000000 Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 79.2 48.4 28.7 12.0 38.5 1.6 59.7 4.0 32.2 21.3 33.7 57.8 63.6 16.8 13.6 49.1 19.3 24.3 37.5 70.3 41.2 21.6 33.8 8.6 94.3 23.5 39.0 16.0 19.2 809.6 6.7 4.1 79.0 25.1 23.0 39.8 106.4 15.9 35.6 31.7 10.8 20.6 26.6 52.3 34.5 87.9 86.5 27.1 7.8 11.2 14.3 7.2 29.0 10.9 0.0 16.1 1.3 8.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 74.4 0.0 7.2 0.1 0.0 0.0 0.0 0.5 0.3 16.9 0.0 0.0 0.0 0.3 0.0 29.1 0.3 0.3 0.0 0.2 0.0 0.5 0.0 0.0 38.7 0.0 0.7 0.5 0.0 0.1 0.0 0.0 1.0 0.0 1.0 1.3 8.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 2.0 28.7 38.5 4.0 32.2 41.2 21.6 39.0 16.0 25.1 27.1 863.6 748.9 16.1 0.9 31.6 0.0 58.9 40.8 58.9 295.7 15.7 0.0 12.0 0.0 8.2 17.6 308.3 107.7 0.0 270.1 10.2 30.9 1.4 23.3 4.9 1257.5 1.6 46.9 532.2 311.7 43.1 29.7 100.6 38.8 4.6 398.3 0.8 308.4 78.7 10.3 0.3 1.8 97.0 15.6 7.0 5.3 24.6 21.6 7.5 165.1 1.7 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955452-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "blood: 137.2;bone marrow: 236.7" "Cell type enriched" "Detected in some" 11 "Kupffer cells: 219.4" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 37.8;eosinophil: 137.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 137.2" "Group enriched" "Detected in some" 318 "HL-60: 54.9;NB-4: 54.8;THP-1: 147.0;U-937: 133.3" HPA044983 Enhanced "Secreted to blood" NA NA 300000000 "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 2.7 3.2 4.8 2.0 9.3 236.7 0.5 0.9 3.7 0.9 0.6 1.4 0.1 0.5 0.7 0.5 0.5 3.2 0.9 3.7 3.9 1.8 1.2 1.3 6.6 7.2 4.7 0.1 0.5 2.5 0.5 0.6 0.8 4.9 0.5 0.6 0.1 0.7 0.5 0.9 0.9 0.6 2.1 10.5 19.4 0.9 0.6 3.7 0.1 0.5 0.1 0.6 1.4 0.3 0.0 20.0 137.2 11.5 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 54.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 147.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 133.3 0.0 37.8 11.5 137.2 0.0 2.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 1.0 0.0 0.2 0.2 0.0 3.3 4.8 9.3 0.9 3.7 3.9 1.8 4.7 0.1 4.9 3.7 3.0 0.3 0.8 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.9 13.1 0.0 0.0 1.8 219.4 1.1 0.3 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 19.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3544793-3558616 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA Nucleoplasm Cytosol "HPA034817: , HPA043037: AB_2678280" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" 16.6 12.8 10.1 14.5 15.4 14.7 16.1 11.0 13.1 9.7 12.1 11.4 10.8 11.8 13.3 14.0 14.1 10.0 11.0 18.5 13.1 10.3 10.9 17.0 11.2 18.3 12.9 11.4 10.1 15.1 10.5 10.8 11.5 12.3 11.2 12.6 9.5 11.2 16.0 35.3 11.3 11.3 17.7 11.9 12.4 11.8 13.8 12.5 10.9 10.1 10.3 14.5 12.8 11.8 16.6 15.9 7.4 12.8 17.2 14.6 10.8 8.8 20.6 7.1 12.1 7.5 7.8 15.9 14.5 12.6 12.4 10.0 15.7 10.7 17.0 15.7 13.0 17.8 9.7 11.9 11.8 9.9 12.7 7.8 14.7 12.2 26.3 14.2 19.1 13.9 6.9 9.9 13.4 15.8 5.4 10.9 27.2 20.0 17.0 12.7 17.5 11.3 10.7 13.8 17.7 15.4 13.8 11.7 17.8 7.5 15.6 12.0 15.7 12.3 8.6 12.1 6.9 7.3 7.3 11.2 16.4 11.2 13.0 20.1 25.2 34.1 28.4 15.3 14.4 21.4 2.8 11.5 7.4 14.5 12.8 14.6 16.6 12.7 13.6 14.2 13.8 12.9 12.5 3.2 17.2 11.1 15.9 11.2 10.8 10.1 15.4 11.0 13.1 13.1 10.3 12.9 11.4 12.3 12.5 20.8 5.8 33.5 22.9 6.6 24.6 21.5 10.2 13.4 6.8 3.5 19.6 27.2 31.5 32.0 2.8 17.3 13.6 0.0 42.6 35.7 17.7 24.8 27.6 15.3 27.4 33.4 14.5 14.1 16.4 2.3 12.7 15.4 10.1 37.9 11.2 16.4 36.8 7.0 24.8 20.1 17.0 19.4 19.0 18.4 29.0 10.7 30.6 16.0 14.7 29.8 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806556-12815201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 44.8" "Cell type enhanced" "Detected in many" 8 "Extravillous trophoblasts: 97.8;Spermatocytes: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol No No Nucleoplasm Cytosol "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favorable (1.18e-4)" "prognostic favorable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favorable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavorable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 6.5 5.5 6.4 11.4 10.6 21.9 6.6 11.0 7.5 6.8 6.6 9.2 1.6 8.6 6.8 4.4 14.1 6.0 5.7 5.1 6.7 4.8 8.7 5.9 5.5 9.2 10.6 5.8 7.3 7.0 6.2 4.1 11.8 6.1 5.3 5.7 5.5 8.8 4.3 7.1 13.4 7.1 4.4 7.8 12.0 7.4 14.1 8.4 44.8 8.6 13.4 17.4 6.0 8.0 11.3 7.8 7.1 6.8 12.9 8.6 5.0 14.9 11.3 6.8 6.8 1.0 1.9 8.4 7.0 2.9 10.5 12.1 8.9 5.7 16.0 10.5 1.6 5.9 8.9 5.6 6.9 5.8 8.7 15.1 7.7 12.0 6.8 0.8 7.0 7.1 1.0 1.7 8.8 3.2 2.0 4.0 13.1 10.6 4.8 5.0 25.7 12.9 7.0 6.8 5.6 19.7 13.9 9.9 11.5 2.6 5.9 14.2 8.3 7.5 2.8 3.2 3.1 7.4 4.4 3.8 12.5 6.3 17.7 11.5 11.6 12.8 12.7 7.4 11.3 10.0 7.1 6.8 6.4 8.6 6.6 7.0 9.8 7.0 6.1 4.2 11.3 6.6 6.5 6.8 12.9 5.9 7.8 5.5 5.0 6.4 10.6 11.0 7.5 6.7 4.8 10.6 5.8 6.1 8.4 0.0 1.6 10.4 15.3 12.5 15.9 2.4 10.2 4.0 1.2 0.0 3.9 40.3 0.0 3.9 12.7 4.9 4.6 0.0 5.4 97.8 9.3 6.6 3.5 3.4 41.5 7.9 8.1 10.4 10.3 15.1 7.8 11.9 11.8 6.4 7.7 10.1 1.9 7.0 4.6 0.8 11.2 6.5 11.3 51.9 45.0 11.5 19.0 12.5 19.0 7.3 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88610272-88963721 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Protein phosphatase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 9.1 12.1 10.2 19.6 12.2 14.2 9.9 18.5 13.1 10.0 8.1 8.7 7.0 7.4 11.1 7.2 12.5 8.7 7.2 9.6 10.5 16.0 9.4 11.8 9.4 26.3 9.8 6.4 10.4 6.6 12.1 23.1 11.6 11.1 9.8 9.8 9.4 8.4 11.6 10.5 9.0 10.7 10.7 10.7 14.3 7.5 15.0 10.4 28.0 10.0 7.8 28.2 10.9 13.8 18.6 4.4 5.7 4.6 8.0 8.4 4.3 5.7 8.8 13.7 17.5 8.1 8.5 8.2 13.2 8.6 10.7 13.6 10.0 4.4 14.9 10.8 9.4 14.2 7.2 16.0 10.6 19.7 20.2 12.5 19.3 7.9 8.0 6.6 20.7 11.0 5.4 9.3 11.1 10.8 9.2 9.4 8.2 19.1 12.0 15.8 7.6 9.1 14.8 8.2 9.5 7.7 18.0 21.2 8.4 9.6 8.9 8.1 11.6 10.9 6.6 7.2 13.6 7.1 20.8 7.5 8.7 8.0 9.8 17.7 10.9 19.0 8.4 12.8 15.5 15.8 3.5 3.0 5.7 6.4 4.6 6.4 18.6 7.2 7.9 4.4 16.8 8.2 8.4 2.5 8.0 3.9 3.1 6.7 4.3 10.2 12.2 18.5 13.1 10.5 16.0 9.8 6.4 11.1 10.4 0.0 18.1 34.7 7.8 7.3 19.8 9.2 2.5 13.4 18.2 12.2 37.3 8.7 0.0 5.7 4.9 4.7 5.9 0.0 4.3 8.0 7.1 6.8 8.1 8.6 6.7 14.3 8.7 6.2 7.5 3.6 5.5 9.8 3.3 6.4 5.7 8.7 5.6 3.5 7.4 5.8 43.3 6.5 7.5 19.9 21.7 7.5 9.8 13.8 6.3 5.8 RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Enterocytes: 152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 12.1;granulocytes: 12.3;monocytes: 17.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus" "Secreted - unknown location" NA NA 6600000 "Golgi apparatus" "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: AB_2684537" "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" 18.5 22.0 6.4 14.9 8.2 9.5 16.7 9.2 11.0 17.8 34.2 13.5 21.2 31.1 17.4 18.7 33.2 19.2 21.8 11.5 6.1 4.6 22.5 18.3 21.5 14.1 7.0 5.4 18.0 19.5 11.6 10.4 26.3 9.0 18.4 26.8 16.4 25.1 13.6 10.0 18.3 66.6 12.8 8.1 22.7 15.7 21.2 6.0 13.9 28.4 19.1 24.7 17.6 17.5 2.3 12.1 12.3 17.0 1.6 3.1 2.2 19.1 20.9 12.5 18.7 20.4 19.2 31.4 14.8 28.8 18.6 21.0 15.0 24.6 4.2 19.1 26.1 11.5 34.9 15.9 29.0 13.0 11.4 20.5 10.5 10.0 14.0 17.4 26.7 37.1 17.5 30.0 16.6 19.1 23.1 33.4 10.4 23.8 6.2 18.8 17.5 3.6 11.4 17.6 30.6 10.4 14.0 17.6 29.6 38.6 17.5 14.4 12.2 36.7 45.8 14.8 25.3 34.8 15.2 23.8 8.7 11.8 8.5 18.0 13.9 11.2 3.8 8.7 22.7 17.4 10.8 9.2 12.3 1.9 15.7 2.6 1.6 2.0 2.2 12.1 2.3 1.8 2.1 6.7 1.6 17.0 4.5 3.1 2.2 6.4 8.2 9.2 11.0 6.1 4.6 7.0 5.4 9.0 6.0 8.9 19.2 23.6 35.3 25.5 11.5 9.0 43.3 13.4 15.9 24.4 9.8 99.1 16.6 59.5 4.4 20.4 152.6 0.0 44.9 74.5 19.0 29.0 15.0 46.6 92.1 11.1 43.1 27.0 67.5 3.8 23.6 48.7 23.6 85.6 66.6 10.8 41.4 81.6 21.5 50.1 7.7 25.8 18.6 15.7 8.2 18.9 73.2 17.5 73.0 31.8 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Enterocytes: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036772, HPA036773" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA036772: AB_10670848, HPA036773: " "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favorable (7.43e-4)" "prognostic unfavorable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 17.2 13.7 10.1 13.7 8.8 17.2 48.4 7.2 10.5 11.0 21.0 9.5 11.8 18.6 8.0 8.9 22.1 8.0 22.3 28.3 9.2 6.0 18.2 26.7 32.2 54.1 12.9 8.2 7.1 40.0 7.7 4.3 10.1 8.1 14.9 9.1 7.0 21.5 13.5 26.5 22.5 31.0 11.4 9.7 25.7 20.0 5.9 7.6 23.1 8.8 16.7 12.1 14.4 18.8 7.0 7.6 22.4 9.1 7.6 12.4 5.4 6.9 11.7 2.6 6.9 9.6 10.0 8.9 4.5 11.2 5.0 6.3 3.2 20.6 2.0 2.3 11.3 7.1 7.6 2.9 8.4 0.5 12.2 4.0 4.6 3.8 18.9 24.1 3.0 8.4 11.8 13.6 2.6 5.2 8.1 17.3 8.0 3.4 13.6 3.4 9.8 3.7 11.3 3.4 13.6 4.7 7.9 3.9 16.9 20.5 9.6 2.4 5.2 3.0 10.4 20.3 3.1 7.3 13.8 11.8 5.5 5.7 7.6 5.1 12.9 1.9 2.3 11.3 8.4 8.2 5.8 9.1 22.4 12.4 7.8 10.6 7.0 9.6 11.1 6.4 6.8 5.4 8.1 16.0 7.6 7.6 7.6 11.1 5.4 10.1 8.8 7.2 10.5 9.2 6.0 12.9 8.2 8.1 7.6 20.8 28.4 28.0 12.0 6.9 6.3 30.7 15.3 2.7 10.3 12.2 0.0 6.1 14.9 22.4 2.6 17.8 92.4 0.0 42.5 5.7 9.9 19.0 33.5 37.6 38.2 3.2 25.3 28.3 58.8 3.7 8.1 30.5 21.9 22.6 46.2 12.2 47.4 37.7 12.7 26.5 6.2 12.9 16.5 0.9 8.3 8.2 4.2 40.6 33.1 19.2 RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92298965-92402056 "Enzymes, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Cone photoreceptor cells: 104.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported Nucleoli,Cytosol No No "Nucleoli, Cytosol" "HPA046443: AB_2679669" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.71e-2)" "unprognostic (4.12e-2)" "unprognostic (4.96e-3)" "unprognostic (5.73e-2)" "unprognostic (1.23e-3)" "unprognostic (3.29e-2)" "unprognostic (8.01e-3)" "unprognostic (4.09e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (7.02e-4)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.62e-3)" "unprognostic (4.10e-2)" 6.8 7.0 7.8 7.3 10.5 12.0 7.6 27.2 11.6 8.4 6.3 7.1 7.2 6.6 11.1 11.5 5.6 6.3 5.5 5.9 8.1 8.6 8.1 10.6 5.2 8.2 7.7 6.7 8.2 8.6 9.4 16.1 6.7 11.7 7.6 5.8 6.4 7.2 7.1 10.5 10.7 6.3 7.4 9.9 7.6 6.4 6.7 8.7 12.8 9.4 6.5 6.3 6.6 7.6 4.4 3.5 4.9 2.4 4.0 4.8 1.2 6.3 3.9 6.8 6.3 5.6 7.2 5.8 5.0 3.5 3.3 2.7 2.8 2.9 9.5 8.7 3.7 4.5 4.4 5.6 3.2 5.1 6.5 4.0 5.8 7.0 3.7 3.3 10.0 5.8 3.7 4.0 4.2 4.1 4.9 3.5 5.9 5.9 6.4 5.0 3.3 8.4 6.3 5.3 3.6 4.4 6.3 9.0 4.1 4.3 5.7 6.4 4.7 8.1 7.5 4.0 5.3 3.9 7.7 6.1 5.0 6.4 5.7 7.1 6.2 7.1 5.0 3.5 6.3 3.4 4.8 2.4 1.9 4.1 1.7 4.8 3.4 3.2 3.5 1.8 4.4 3.5 3.8 4.9 4.0 1.9 3.5 2.8 1.2 7.8 10.5 27.2 11.6 8.1 8.6 7.7 6.7 11.7 8.7 59.6 66.2 8.2 15.1 8.1 55.5 21.2 5.1 75.0 68.2 7.0 104.1 17.6 10.0 16.4 39.3 17.1 7.7 23.3 11.9 12.3 13.6 12.8 59.1 7.4 8.5 33.4 12.1 8.0 10.8 4.7 17.5 8.8 1.7 15.4 11.9 39.3 12.8 10.7 20.1 13.0 87.8 25.8 12.0 18.9 18.8 8.5 19.8 24.2 11.1 9.8 RPE65 "BCO3, LCA2, rd12, RP20" ENSG00000116745 "RPE65, retinoid isomerohydrolase" Q16518 1 68428822-68449959 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Isomerase" "Disease mutation, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "retina: 268.3" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 9.8;Rod photoreceptor cells: 17.3" "Group enriched" "Detected in some" 10 "glioma: 5.8;head and neck cancer: 1.5" "Group enriched" "Detected in many" 5 "hypothalamus: 6.0;midbrain: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.2;PC-3: 10.6;U-2 OS: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (1.59e-1)" "unprognostic (1.88e-1)" "unprognostic (3.15e-1)" "prognostic favorable (9.75e-4)" "unprognostic (4.55e-2)" "unprognostic (5.91e-2)" "unprognostic (6.59e-4)" "unprognostic (2.98e-2)" "unprognostic (1.57e-1)" "unprognostic (8.24e-2)" "unprognostic (3.21e-4)" "unprognostic (2.11e-1)" "unprognostic (2.05e-1)" "unprognostic (3.48e-2)" "unprognostic (8.40e-3)" 0.0 0.0 0.9 0.1 0.7 0.0 1.0 0.1 3.8 0.2 0.1 1.3 1.4 0.4 1.4 0.7 0.8 0.6 0.2 0.0 1.5 6.0 0.0 0.0 0.0 0.1 8.8 0.1 0.1 0.0 0.0 0.0 0.0 1.2 4.2 0.2 268.3 0.2 10.5 0.0 0.0 0.1 0.5 1.4 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.6 1.5 6.0 8.8 0.1 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 17.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 RPP14 P14 ENSG00000163684 "Ribonuclease P/MRP subunit p14" O95059 3 58306247-58324695 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036194 Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA036194: AB_10672082" "unprognostic (6.05e-2)" "unprognostic (2.02e-2)" "unprognostic (1.50e-3)" "unprognostic (1.36e-1)" "unprognostic (4.08e-3)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (3.76e-2)" "prognostic favorable (3.07e-10)" "unprognostic (5.19e-3)" "unprognostic (2.36e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (5.78e-2)" 7.1 8.5 8.3 5.7 12.9 5.3 7.1 15.8 10.7 6.6 8.6 5.9 6.6 10.2 8.2 7.8 8.5 7.4 6.2 11.8 7.2 6.8 11.2 15.0 5.6 7.6 6.5 9.9 8.4 11.9 10.8 9.4 6.0 7.2 7.4 8.2 9.0 8.5 7.0 53.5 7.4 9.1 11.7 5.5 7.7 7.7 9.1 5.9 6.3 8.1 18.5 8.5 7.2 7.0 4.6 6.6 4.7 9.8 9.8 6.4 3.5 10.1 8.1 9.4 7.5 7.9 8.5 10.4 8.6 9.3 12.4 14.0 12.3 6.7 12.2 2.0 11.5 10.8 6.2 14.1 12.8 12.1 8.5 7.4 11.6 9.7 6.7 7.7 19.9 9.7 9.3 12.4 14.7 14.1 6.2 9.7 15.0 9.9 8.7 12.0 5.5 13.5 7.0 12.3 8.4 15.4 5.5 7.4 11.8 9.0 14.6 5.9 10.5 8.1 9.7 11.6 6.8 9.3 9.6 8.8 9.4 10.5 9.9 16.3 13.0 22.3 17.6 10.7 14.0 6.6 3.0 5.7 4.7 4.2 4.9 5.6 4.1 5.5 5.8 6.6 4.6 6.4 6.2 2.6 9.8 9.8 6.2 3.0 3.5 8.3 12.9 15.8 10.7 7.2 6.8 6.5 9.9 7.2 5.9 8.9 11.0 7.0 7.1 27.7 24.7 26.6 5.1 8.1 5.7 3.5 23.6 7.2 10.0 5.3 0.7 7.2 11.7 0.0 5.3 5.2 8.4 6.9 3.5 17.9 5.4 17.5 9.2 12.3 11.4 0.9 11.5 9.5 21.9 8.2 12.5 12.9 6.2 3.5 9.2 10.1 28.1 0.0 20.5 8.6 13.5 37.6 8.6 7.0 13.4 6.2 RPP21 "C6orf135, Em:AB014085.3, FLJ22638" ENSG00000241370 "Ribonuclease P/MRP subunit p21" Q9H633 6 30345131-30346884 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 20.6;EFO-21: 22.1;HEK 293: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.73e-1)" "unprognostic (1.09e-3)" "unprognostic (2.83e-1)" "unprognostic (4.65e-2)" "unprognostic (1.78e-1)" "unprognostic (6.46e-2)" "unprognostic (2.18e-2)" "unprognostic (8.37e-2)" "unprognostic (2.86e-1)" "unprognostic (1.65e-2)" "unprognostic (2.65e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.54e-2)" "unprognostic (1.01e-2)" "unprognostic (4.13e-2)" "prognostic favorable (6.78e-5)" 21.9 30.8 16.5 12.4 20.3 10.0 16.7 14.6 21.4 19.4 20.5 10.7 11.0 13.5 20.1 11.4 38.6 26.2 12.6 16.2 13.1 14.6 15.9 16.7 8.3 13.2 13.6 11.7 22.1 27.7 4.1 11.2 10.7 12.5 19.1 3.3 10.2 11.3 16.1 32.5 45.9 15.4 27.4 12.3 11.8 22.8 9.8 10.9 12.3 19.1 8.9 15.6 19.2 16.6 20.1 11.5 11.1 13.1 6.7 17.7 9.6 17.5 0.0 0.0 20.6 8.0 5.7 9.7 4.5 4.0 6.2 6.4 0.3 0.0 13.0 22.1 2.2 7.1 0.1 0.0 9.4 1.5 6.1 24.1 9.6 0.0 2.3 15.3 0.0 0.0 1.6 1.3 0.2 1.1 3.0 0.0 18.2 3.0 5.5 2.5 0.9 0.0 0.7 15.3 0.0 0.0 5.5 0.0 0.6 8.5 8.5 20.0 2.3 0.0 4.4 11.3 1.5 0.0 0.6 0.3 0.0 0.0 14.7 0.1 4.9 12.4 5.7 0.0 1.2 0.0 11.1 13.1 8.4 6.6 11.5 9.1 20.1 11.7 6.9 11.5 16.8 14.1 8.0 4.0 6.7 12.5 4.6 17.7 9.6 16.5 20.3 14.6 21.4 13.1 14.6 13.6 11.7 12.5 10.9 6.0 13.6 16.4 9.6 31.7 3.5 1.1 12.7 16.0 38.7 24.4 0.0 12.9 6.6 30.5 3.0 6.7 27.4 46.7 52.0 15.8 10.5 6.7 12.7 14.3 9.2 1.6 40.9 11.1 14.6 1.4 12.7 14.9 23.6 15.4 27.1 2.3 36.4 37.7 9.9 17.7 3.0 6.5 19.4 17.7 23.2 35.4 9.5 22.4 32.6 9.6 RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954416-74957464 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 79.4;Hofbauer cells: 60.4;Rod photoreceptor cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.7;monocytes: 6.4" "Cell line enhanced" "Detected in many" "HHSteC: 18.6;SCLC-21H: 17.1;SK-MEL-30: 25.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" 3.9 7.3 3.0 1.9 4.6 0.0 2.2 3.2 14.0 3.4 6.7 3.7 1.2 6.0 1.7 1.3 3.3 1.8 3.7 2.5 2.5 6.8 2.6 1.9 5.1 2.7 8.0 5.1 12.0 4.9 9.0 2.8 6.1 10.6 2.1 4.1 3.2 2.4 1.3 1.9 2.1 4.6 2.0 7.9 6.2 5.6 1.9 1.8 3.1 4.9 2.6 2.5 4.1 2.4 2.3 16.7 0.3 6.4 0.3 2.7 1.4 8.9 6.8 1.7 0.0 0.6 0.4 2.9 1.7 2.0 0.5 0.4 9.2 8.2 0.0 7.9 1.7 0.5 2.7 5.3 0.3 0.1 3.3 0.2 0.0 7.9 0.2 18.6 0.0 5.3 2.4 0.2 3.4 0.0 0.3 7.9 2.3 6.0 0.0 1.7 3.4 1.4 2.4 8.2 15.7 2.7 0.0 0.0 6.0 1.6 0.1 17.1 12.8 12.8 11.3 25.6 0.9 2.2 7.1 1.8 0.0 0.7 1.6 0.0 0.1 0.0 0.0 0.9 13.9 10.0 0.0 3.3 0.0 1.5 6.4 0.9 2.3 1.1 1.3 3.3 1.9 2.7 2.1 0.3 0.3 4.8 16.7 0.4 1.4 3.0 4.6 3.2 14.0 2.5 6.8 8.0 5.1 10.6 1.8 3.0 0.6 4.5 6.4 9.7 79.4 1.5 10.2 0.0 1.2 8.7 3.9 1.7 11.6 11.4 0.3 5.8 17.2 0.0 16.7 3.9 18.6 13.1 0.0 1.0 60.4 20.6 9.8 36.8 12.1 0.9 36.5 7.9 13.5 22.6 9.4 7.8 15.6 15.8 28.3 12.8 56.0 12.9 10.3 0.5 7.0 10.0 1.9 2.5 18.4 8.7 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871716-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" NA NA "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 24.2 19.0 20.9 16.8 20.3 27.2 22.3 26.0 24.0 18.9 19.0 16.2 16.3 11.5 25.2 18.6 23.8 19.2 16.0 26.6 19.8 16.8 20.6 18.4 17.1 23.2 18.5 20.4 23.9 17.7 37.7 23.6 23.6 19.3 18.8 19.3 18.7 19.2 16.5 35.9 23.5 16.4 20.6 19.2 21.3 19.2 32.0 21.6 31.2 18.1 24.0 26.3 21.7 18.9 19.4 22.2 16.2 19.5 14.2 20.3 16.2 28.6 19.1 20.0 24.1 13.0 14.1 7.1 20.5 18.5 34.4 36.1 32.2 23.1 16.9 15.7 13.0 22.4 20.1 26.6 18.2 35.5 27.1 18.3 11.4 12.2 25.4 12.4 23.0 14.4 11.5 11.9 25.9 29.4 14.5 19.4 15.6 22.6 15.5 22.7 17.7 26.6 31.3 12.4 16.3 21.7 14.9 17.1 17.8 12.9 13.6 10.9 10.9 12.0 8.7 24.1 19.2 23.5 14.6 11.0 17.2 17.2 9.7 42.3 10.5 26.8 36.3 21.5 12.5 13.1 4.3 19.5 16.2 17.1 18.7 18.6 19.4 19.6 18.7 22.2 16.7 17.0 18.5 2.2 14.2 15.3 20.7 20.3 16.2 20.9 20.3 26.0 24.0 19.8 16.8 18.5 20.4 19.3 21.6 29.8 20.0 24.7 27.9 30.6 18.6 39.9 22.9 17.4 20.5 14.0 17.7 50.9 26.6 34.6 73.2 18.4 8.7 0.0 30.3 55.9 20.4 16.0 23.1 12.4 49.9 15.9 19.0 20.3 22.6 37.3 26.7 27.6 21.9 32.5 17.8 20.3 27.7 14.0 27.6 27.1 20.1 38.8 28.1 53.2 47.3 29.6 28.3 27.3 17.5 21.8 RPP38 ENSG00000152464 "Ribonuclease P/MRP subunit p38" P78345 10 15097180-15139818 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 14 "Early spermatids: 439.8;Late spermatids: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045128, HPA050398" Approved Supported Nucleoli NA NA Nucleoli "HPA045128: AB_2797230, HPA050398: AB_2732560" "unprognostic (1.75e-1)" "unprognostic (3.91e-2)" "unprognostic (3.76e-2)" "unprognostic (1.51e-1)" "unprognostic (9.93e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.41e-2)" "unprognostic (4.86e-1)" "unprognostic (1.57e-3)" "unprognostic (3.42e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (6.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.11e-2)" "prognostic favorable (2.89e-6)" 13.1 12.2 12.4 10.7 13.6 9.7 18.3 22.4 12.4 13.6 16.7 12.0 15.8 14.4 15.7 16.1 15.2 18.2 10.3 10.0 11.6 10.2 17.4 21.6 12.5 16.3 15.0 10.0 14.4 16.8 11.3 16.0 17.4 12.7 18.4 15.7 11.7 17.1 14.9 20.9 14.8 17.9 14.3 11.5 16.7 13.5 38.6 12.7 18.8 19.8 13.9 18.5 13.4 13.6 31.0 25.7 23.4 24.5 18.6 31.4 20.2 21.0 15.9 8.8 11.2 11.9 12.2 15.4 10.2 7.7 16.0 16.5 16.0 22.2 17.7 11.0 9.6 13.3 19.7 17.5 17.7 14.8 13.4 15.9 18.2 9.7 14.1 25.5 10.2 15.3 14.5 24.5 13.1 11.6 12.5 12.8 18.0 20.9 12.6 12.2 17.3 18.3 11.2 10.1 26.3 7.8 15.0 8.8 21.9 20.5 8.3 8.3 10.5 14.1 24.5 28.2 14.9 21.9 16.5 11.0 7.5 12.9 15.7 13.4 17.6 18.7 24.0 14.6 12.5 7.0 8.5 24.5 23.4 25.6 23.7 25.1 28.8 26.2 31.4 25.3 31.0 30.6 27.8 8.3 18.6 18.6 25.7 22.0 20.2 12.4 13.6 22.4 12.4 11.6 10.2 15.0 10.0 12.7 12.7 14.9 15.8 18.2 26.3 27.9 13.0 6.5 7.6 107.1 38.7 8.7 5.9 26.5 23.2 28.9 439.8 16.8 18.2 0.0 29.4 37.0 16.2 26.9 12.7 24.6 21.7 7.9 12.7 14.7 16.5 144.4 21.9 21.4 8.5 14.4 19.9 14.9 25.8 21.0 18.7 25.9 29.8 12.9 11.3 28.6 38.0 31.6 26.9 20.8 20.5 39.4 RPP40 "bA428J1.3, RNASEP1" ENSG00000124787 "Ribonuclease P/MRP subunit p40" O75818 6 4994732-5004063 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035685, HPA035686" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA035685: AB_2674734, HPA035686: AB_10670153" "unprognostic (2.93e-2)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.10e-6)" "unprognostic (8.00e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (5.41e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-2)" "unprognostic (6.44e-2)" "unprognostic (8.17e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (7.54e-8)" "unprognostic (1.54e-1)" "unprognostic (5.10e-1)" "unprognostic (4.08e-2)" "unprognostic (2.19e-1)" 6.9 16.8 10.8 7.2 10.7 6.7 11.1 3.5 11.9 6.0 5.5 4.2 6.3 4.6 6.1 6.6 11.9 5.5 4.7 5.5 10.0 8.8 5.6 10.8 3.9 10.1 9.9 5.8 6.2 7.8 5.2 8.6 5.6 9.1 5.3 5.3 1.5 4.0 6.7 7.7 9.8 3.6 7.5 5.3 6.8 4.3 10.5 8.0 6.1 5.6 13.0 8.3 9.1 6.9 7.8 12.3 0.0 11.1 7.9 8.4 5.0 6.4 10.8 3.4 9.7 6.4 8.1 10.9 6.4 3.2 12.3 9.8 14.7 5.0 14.0 28.3 6.6 16.9 6.9 7.0 9.9 11.2 5.3 14.2 8.8 7.0 19.9 7.5 11.3 5.0 6.3 8.5 12.2 12.2 2.7 12.0 12.9 13.9 2.8 8.9 18.4 5.7 19.5 5.7 7.7 17.6 12.2 6.5 25.6 6.2 7.0 12.3 3.6 6.0 5.8 6.4 9.5 10.5 9.4 5.7 16.2 10.9 10.9 14.5 5.0 21.1 11.0 3.0 19.0 8.3 0.0 6.9 0.0 3.4 11.1 5.0 7.8 5.9 4.1 12.3 6.5 8.1 7.2 0.0 7.9 3.5 5.9 8.4 5.0 10.8 10.7 3.5 11.9 10.0 8.8 9.9 5.8 9.1 8.0 0.0 0.6 4.5 7.0 11.0 0.2 3.6 0.0 5.3 4.5 1.8 0.0 11.1 10.0 8.1 5.5 7.0 0.4 0.0 8.1 10.7 6.0 3.1 0.0 5.8 9.9 0.0 2.9 6.7 2.1 2.1 5.2 3.4 8.5 1.8 3.1 1.3 3.9 2.3 4.6 11.7 0.2 0.0 7.2 11.4 26.8 12.9 8.0 1.9 6.8 7.0 RTEL1 "bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL" ENSG00000258366 "Regulator of telomere elongation helicase 1" Q9NZ71 20 63657810-63696253 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease mutation, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA020622, HPA067329, HPA078328" Approved "Nuclear speckles,Nuclear bodies" NA NA "Nuclear speckles, Nuclear bodies" "HPA020622: AB_2732425, HPA067329: AB_2685823, HPA078328: AB_2732380" "unprognostic (3.63e-2)" "unprognostic (8.08e-3)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.27e-1)" "unprognostic (9.30e-3)" "unprognostic (2.59e-1)" "unprognostic (3.64e-2)" "unprognostic (3.30e-2)" "unprognostic (9.05e-2)" "unprognostic (4.09e-2)" "unprognostic (9.50e-2)" "unprognostic (8.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" "unprognostic (8.84e-2)" 8.4 14.3 9.4 11.5 12.4 14.2 7.9 25.6 11.8 9.1 11.1 11.2 10.9 9.8 15.4 7.4 7.0 9.5 9.3 6.2 8.0 6.9 7.1 7.2 8.9 7.8 7.5 12.1 10.6 17.8 7.2 18.2 9.8 8.2 10.2 4.8 10.2 12.9 10.2 10.2 8.2 10.1 8.8 4.4 11.6 10.4 17.6 8.9 9.1 11.9 4.9 9.5 9.3 9.0 1.7 3.6 0.0 3.3 0.4 3.0 2.4 5.3 7.3 5.2 10.1 1.1 1.2 9.7 11.0 2.9 17.2 4.5 14.5 4.5 7.1 5.7 3.3 6.5 9.9 3.6 7.2 4.1 3.5 7.3 8.8 12.6 13.8 3.8 8.6 16.1 1.5 4.0 4.2 5.3 3.3 5.8 12.7 10.8 6.8 3.8 5.7 13.3 11.1 5.1 4.5 15.3 10.7 4.9 7.3 2.8 6.5 10.4 6.3 6.1 18.0 1.4 2.5 4.7 9.7 7.7 19.5 6.4 6.7 8.4 6.3 2.6 4.5 4.7 6.1 6.7 0.0 2.7 0.0 3.0 3.3 1.6 0.9 1.7 2.0 3.6 1.7 2.9 1.1 0.0 0.4 2.6 3.2 1.4 2.4 9.4 12.4 25.6 11.8 8.0 6.9 7.5 12.1 8.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 RUVBL1 "ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a" ENSG00000175792 "RuvB like AAA ATPase 1" Q9Y265 3 128064778-128153914 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Growth regulation, Mitosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Ciliated cells: 208.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019947, HPA019948" Enhanced Supported Nucleoplasm,Cytosol NA NA 47000 "Nucleoplasm, Cytosol" "HPA019947: AB_1856516, HPA019948: AB_1856514" "unprognostic (7.40e-2)" "unprognostic (2.17e-1)" "unprognostic (1.28e-1)" "unprognostic (4.73e-2)" "unprognostic (3.55e-1)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.21e-8)" "unprognostic (2.43e-2)" "unprognostic (3.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.25e-2)" "unprognostic (7.39e-2)" "unprognostic (2.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.61e-1)" "unprognostic (9.27e-2)" 17.6 15.1 10.7 15.8 14.2 11.9 13.9 7.9 14.0 12.5 11.6 12.9 14.3 8.4 19.2 11.4 19.2 37.3 11.3 18.6 11.4 13.6 20.9 13.7 12.9 18.7 10.0 9.8 15.4 13.6 26.5 14.2 19.9 13.0 12.0 14.1 11.5 10.2 12.0 12.9 11.8 10.2 16.1 8.8 21.9 10.9 44.7 10.3 33.4 15.2 18.1 23.9 12.6 15.0 10.6 8.7 1.5 7.9 10.9 20.2 7.2 26.9 24.5 15.1 24.5 11.8 11.5 19.7 13.2 11.4 25.5 17.6 25.6 16.1 38.3 13.2 12.6 19.7 21.5 40.1 28.1 29.8 15.6 19.7 31.8 14.2 17.1 12.2 29.7 10.2 11.7 14.8 21.4 27.6 9.7 17.1 14.6 26.0 9.0 14.5 38.4 31.8 22.5 37.9 30.5 21.0 26.2 18.3 26.6 15.3 10.2 25.3 22.7 14.6 12.1 20.2 14.6 22.0 22.0 11.0 11.6 14.2 17.4 20.0 9.2 14.6 37.6 14.3 18.3 14.5 0.8 4.8 1.5 11.3 7.9 14.6 10.6 13.6 14.0 7.7 10.2 11.5 12.8 0.2 10.9 7.4 8.7 20.2 7.2 10.7 14.2 7.9 14.0 11.4 13.6 10.0 9.8 13.0 10.3 20.8 11.7 25.1 16.5 17.7 16.3 18.7 22.9 208.8 31.8 21.0 2.0 45.7 39.7 29.2 14.5 21.2 2.9 0.0 26.3 53.6 20.6 11.7 25.4 13.2 26.2 22.3 16.3 11.1 5.6 19.6 14.1 10.5 10.1 12.6 12.4 26.0 22.8 14.0 17.3 41.5 16.2 12.9 13.3 96.8 64.3 14.8 20.1 24.9 23.0 11.9 RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993448-49015995 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0" "Group enriched" "Detected in all" 4 "Ciliated cells: 184.7;Early spermatids: 493.7;Late spermatids: 663.3;Spermatocytes: 292.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012432, HPA042880, HPA067966" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Nucleoplasm, Cytosol" Centrosome "CAB012432: , HPA042880: AB_2678210, HPA067966: AB_2685933" "unprognostic (1.71e-1)" "unprognostic (9.06e-3)" "unprognostic (3.51e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (7.06e-3)" "unprognostic (6.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.13e-2)" "unprognostic (7.58e-2)" "unprognostic (2.81e-2)" "unprognostic (2.21e-2)" "unprognostic (7.61e-3)" "unprognostic (1.61e-1)" "unprognostic (2.58e-1)" 6.9 5.3 6.7 7.5 7.1 13.4 4.8 8.2 10.4 4.8 9.9 7.6 6.3 11.2 8.3 5.5 16.1 5.5 7.2 9.1 6.9 6.0 7.6 10.3 5.5 8.2 7.7 8.1 6.5 8.7 1.6 6.4 5.5 6.7 6.0 3.2 6.5 10.0 6.6 27.8 7.7 10.0 3.7 7.1 6.9 10.7 59.0 5.8 14.6 8.8 9.4 8.1 6.4 12.9 12.6 16.4 5.6 14.3 11.0 12.5 15.2 28.9 29.8 3.5 20.0 1.5 2.7 9.4 15.7 6.8 18.0 11.8 15.4 12.6 27.2 12.1 3.1 5.1 15.4 2.2 10.3 2.1 16.5 12.2 17.7 9.0 7.8 5.0 34.8 12.4 3.1 2.1 4.0 2.1 3.3 6.6 23.0 30.7 11.6 1.6 5.9 30.7 4.1 10.8 6.0 4.4 25.5 16.1 17.5 3.2 11.2 14.3 20.6 15.8 13.2 5.6 1.1 11.6 13.4 9.7 11.4 16.8 7.5 38.7 23.5 26.8 28.1 8.4 17.1 16.3 5.6 14.3 4.2 11.1 11.1 11.2 10.9 11.1 9.1 16.4 12.6 12.2 8.0 1.0 11.0 10.8 12.5 12.5 15.2 6.7 7.1 8.2 10.4 6.9 6.0 7.7 8.1 6.7 5.8 11.9 20.2 23.7 40.9 24.6 15.0 38.6 28.1 184.7 36.4 31.4 31.4 91.2 39.7 59.0 493.7 24.1 23.6 23.3 61.9 63.4 32.5 34.0 12.7 31.1 44.6 17.5 16.8 27.6 18.3 663.3 33.4 26.7 25.3 43.3 33.6 23.6 48.7 31.6 40.3 61.6 24.1 19.4 37.1 292.2 46.3 24.1 96.9 25.3 49.4 33.5 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA 7400000 "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" 65.5 43.6 18.7 23.3 17.3 36.4 42.6 11.2 15.5 44.4 38.5 23.0 38.8 20.7 41.8 57.9 40.3 27.3 33.2 30.8 18.7 18.4 56.5 68.2 44.7 41.1 24.7 12.6 55.7 70.9 21.2 41.7 46.0 18.4 44.4 28.0 28.5 43.5 36.2 51.9 23.3 33.3 39.7 31.5 38.4 29.5 28.2 19.7 33.2 74.6 39.3 32.1 49.8 37.8 29.1 44.3 32.6 48.4 34.3 45.9 46.3 23.7 51.3 37.9 58.6 48.1 60.0 29.1 38.0 44.3 31.2 37.4 54.9 59.0 11.8 25.0 46.7 36.9 51.9 52.5 31.9 34.0 29.0 38.8 34.5 58.5 51.6 41.7 25.9 39.1 41.3 40.1 21.5 34.9 50.9 44.1 15.5 34.2 31.8 42.1 55.7 10.6 56.4 40.3 36.1 22.1 13.3 49.0 38.5 70.2 66.7 18.6 41.8 31.6 35.4 85.5 59.4 34.5 60.3 30.0 31.7 23.8 27.0 46.2 31.2 59.2 16.7 34.4 45.7 24.7 20.7 43.8 24.1 28.4 47.3 28.5 29.1 35.4 30.4 43.8 26.6 30.2 30.9 32.6 34.3 48.4 44.3 45.9 46.3 18.7 17.3 11.2 15.5 18.7 18.4 24.7 12.6 18.4 19.7 83.4 82.6 129.4 146.5 95.1 26.0 57.2 214.0 68.3 101.2 122.1 21.6 264.5 202.2 211.7 36.2 236.3 103.8 23.3 215.7 493.0 216.8 157.8 217.7 143.3 324.9 19.1 151.1 167.6 353.0 67.9 277.3 291.4 150.1 267.9 172.8 64.3 169.6 103.7 156.3 255.0 33.2 168.1 121.7 176.8 142.9 104.8 255.7 159.2 214.9 195.4 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139477-59158836 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 132.6" "Cell type enhanced" "Detected in all" 5 "Glandular cells: 405.9;Muller glia cells: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 59.5;Karpas-707: 64.1;RPMI-8226: 129.8;U-266/70: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: AB_2680078" "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 5.9 18.4 30.1 18.6 29.7 11.3 16.0 14.9 25.2 12.2 18.7 24.4 27.8 27.5 9.1 58.0 10.7 9.2 11.1 7.2 27.7 33.9 19.0 66.8 13.0 22.0 41.8 21.3 7.0 96.8 14.6 46.6 8.1 27.1 48.8 16.4 10.0 132.6 34.1 4.3 7.9 21.1 6.6 51.3 23.6 28.4 6.4 25.3 7.3 35.9 8.6 23.4 18.9 5.9 33.6 50.0 10.6 17.6 17.3 34.4 32.6 8.8 10.7 5.8 9.0 3.6 0.6 7.4 8.0 6.9 9.9 6.0 7.5 4.8 20.3 12.7 4.8 7.3 9.5 9.1 6.0 5.7 59.5 12.5 6.5 7.4 22.9 10.8 21.5 9.9 2.0 14.4 6.1 16.6 2.1 3.2 8.7 7.5 64.1 3.5 10.4 8.8 8.6 5.9 14.7 6.6 8.0 5.7 129.8 6.4 7.4 27.1 10.8 4.8 19.5 27.1 3.3 8.8 15.8 2.6 12.0 5.0 4.2 9.6 65.4 48.1 19.9 12.0 14.6 14.7 10.6 13.1 9.4 25.9 15.5 33.1 33.6 27.3 25.2 13.5 17.4 14.3 19.5 2.0 17.3 17.6 50.0 34.4 32.6 30.1 29.7 14.9 25.2 27.7 33.9 41.8 21.3 27.1 25.3 26.8 96.0 46.9 40.1 29.0 63.6 51.8 132.5 95.0 89.9 57.6 47.1 59.9 74.6 117.2 35.1 52.2 73.8 23.3 229.6 80.5 24.9 405.9 46.2 201.1 102.0 47.7 325.7 35.6 28.2 14.8 11.5 58.2 243.0 32.5 93.2 440.4 146.8 74.8 21.5 86.0 65.5 6.5 40.9 97.2 84.1 39.6 125.2 74.3 75.9 57.4 SGSH "HSS, MPS3A, SFMD" ENSG00000181523 "N-sulfoglucosamine sulfohydrolase" P51688 17 80206716-80220923 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 28.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023436, HPA023451" Enhanced "Intracellular and membrane" NA NA "HPA023436: AB_1856806, HPA023451: AB_1856807" "unprognostic (4.33e-2)" "unprognostic (4.03e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-2)" "unprognostic (4.26e-3)" "unprognostic (1.39e-3)" "prognostic unfavorable (7.71e-4)" "prognostic favorable (2.72e-4)" "unprognostic (6.08e-2)" "unprognostic (3.65e-1)" "prognostic favorable (3.10e-4)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.42e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (7.50e-2)" "unprognostic (3.68e-2)" 14.4 37.1 7.8 11.6 7.5 2.3 13.5 5.5 7.3 12.0 11.2 9.3 16.5 8.5 13.8 14.8 11.2 13.2 14.2 8.5 7.9 9.3 16.3 9.9 15.1 19.9 5.5 6.7 11.3 19.5 16.5 13.8 19.2 7.7 17.2 5.8 18.1 18.8 19.5 6.1 14.9 12.3 11.2 6.8 23.3 13.2 8.1 6.7 3.6 16.6 11.4 16.1 14.5 8.9 3.9 16.0 1.8 16.1 6.4 14.4 9.5 1.2 3.7 3.2 6.7 9.4 8.5 4.7 8.4 16.5 11.6 10.6 3.2 4.3 0.0 13.6 7.2 4.6 4.1 2.0 3.5 2.1 4.0 5.1 0.0 9.4 9.4 28.3 0.0 2.9 16.1 4.3 3.3 4.5 1.7 22.8 2.2 3.5 9.4 6.2 6.5 0.1 0.1 2.0 2.8 6.6 0.5 1.8 9.8 7.2 6.5 0.9 6.7 9.3 17.4 4.5 2.5 15.7 0.2 15.6 13.5 3.9 5.1 2.9 15.7 1.8 1.7 6.2 0.0 6.6 0.0 16.1 0.0 10.9 6.8 14.4 3.1 9.2 10.8 16.0 3.9 7.5 6.3 1.8 6.4 6.0 1.1 10.9 9.5 7.8 7.5 5.5 7.3 7.9 9.3 5.5 6.7 7.7 6.7 3.0 9.6 2.4 3.7 4.5 3.1 1.4 7.6 2.7 7.9 7.0 7.9 15.1 0.0 7.2 0.2 7.7 8.5 0.0 13.8 7.3 9.3 5.1 0.0 3.9 15.7 0.0 2.9 10.4 13.2 0.0 10.6 7.9 1.7 5.4 9.9 5.2 7.6 3.5 13.4 4.1 4.0 12.9 4.2 0.2 0.7 4.8 22.5 5.4 6.7 2.4 SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078495 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 123 "intestine: 181.4" "Group enriched" "Detected in some" 7 "Enterocytes: 48.7;Mucus-secreting cells: 79.9;Paneth cells: 46.3;Undifferentiated cells: 29.8" "Cancer enhanced" "Detected in some" "stomach cancer: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.9;CACO-2: 4.1;HeLa: 3.2;NB-4: 3.4;RPMI-8226: 4.9;SH-SY5Y: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011897 Enhanced NA NA "HPA011897: AB_1856840" "unprognostic (2.71e-2)" "unprognostic (1.62e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-1)" "unprognostic (4.41e-2)" 0.1 0.1 0.1 1.4 0.1 0.0 0.1 0.1 0.1 0.1 93.3 0.0 0.0 94.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 5.4 0.0 0.1 0.0 0.1 0.1 181.4 0.0 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 79.9 0.0 0.0 46.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 29.8 0.0 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 56.7;Enterocytes: 65.0;Paneth cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 31.6;ASC TERT1: 32.9;HSkMC: 35.2;OE19: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 1800000 "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 9.0 12.3 9.0 6.7 13.4 1.9 8.2 8.2 16.8 7.0 46.7 15.7 7.3 16.8 5.9 17.8 10.2 9.9 8.4 23.0 10.3 17.6 42.5 28.3 10.7 2.8 18.2 8.1 5.1 11.2 32.4 13.1 7.8 31.4 10.7 51.7 9.9 15.9 8.3 17.3 6.7 25.5 5.4 19.9 7.9 9.3 5.6 8.1 1.9 46.1 11.1 7.0 9.8 4.7 2.7 4.1 8.6 5.8 1.2 4.3 3.2 3.0 4.7 2.8 12.1 31.6 32.9 7.4 5.8 8.2 1.5 0.9 3.6 21.0 1.9 8.5 7.2 3.3 5.9 4.4 6.4 1.5 8.7 1.3 2.9 1.5 3.8 14.9 0.5 2.7 35.2 8.7 3.9 6.0 20.6 10.5 3.8 2.4 13.1 5.0 5.5 0.2 1.3 1.8 32.8 9.8 1.1 0.1 3.2 18.0 4.3 1.0 1.8 15.8 6.5 2.7 8.8 12.7 2.8 11.6 8.4 1.6 9.3 1.4 3.5 2.6 0.4 3.0 1.6 3.4 8.6 5.6 0.3 1.9 4.2 2.2 2.4 3.1 2.0 4.1 2.7 4.3 3.4 1.2 1.2 5.8 2.5 2.2 3.2 9.0 13.4 8.2 16.8 10.3 17.6 18.2 8.1 31.4 8.1 17.9 47.6 2.2 5.0 2.9 6.2 56.7 17.8 12.0 9.1 34.9 0.0 6.7 8.3 9.3 7.8 5.8 65.0 0.0 3.4 7.5 3.3 9.8 1.1 26.0 4.0 4.8 13.9 10.4 3.2 9.8 2.8 2.8 3.3 4.6 27.5 2.3 6.8 57.5 1.1 21.4 1.6 0.0 6.6 12.8 9.1 4.5 5.6 1.0 46.6 6.5 SMARCAD1 "DKFZP762K2015, ETL1, KIAA1122" ENSG00000163104 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" Q9H4L7 4 94207611-94291292 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016737 Approved Enhanced Nucleoplasm NA NA Nucleoplasm "HPA016737: AB_1857271" "unprognostic (5.01e-2)" "unprognostic (5.83e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (8.41e-3)" "unprognostic (9.08e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (2.45e-1)" "unprognostic (3.49e-3)" "unprognostic (3.55e-1)" "unprognostic (2.57e-2)" "unprognostic (7.72e-2)" "unprognostic (2.99e-2)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (3.20e-3)" 12.8 15.4 15.4 22.2 14.6 8.6 20.1 26.7 25.1 15.4 13.6 9.4 14.4 12.6 19.6 17.5 17.2 16.5 13.9 12.9 13.6 14.7 16.6 14.9 21.6 22.8 17.6 11.1 20.8 15.0 17.2 33.0 18.3 14.9 15.4 16.5 10.2 14.9 20.9 11.8 26.5 13.9 15.6 17.9 17.6 13.9 15.3 16.2 42.0 20.2 11.4 17.8 16.0 15.9 5.5 4.3 3.5 3.0 7.5 6.2 2.7 7.4 9.7 30.1 19.7 8.7 14.3 15.6 13.3 12.5 11.1 10.7 8.7 12.2 19.2 9.2 11.4 10.1 6.5 21.2 11.2 16.1 14.7 9.6 13.8 10.5 13.3 12.6 20.1 14.8 14.6 9.3 13.8 17.8 13.8 17.3 16.8 22.8 8.0 16.8 5.9 34.2 10.7 20.9 9.4 4.8 19.9 17.2 9.8 13.0 9.1 17.7 26.2 10.2 17.2 14.6 19.3 8.8 13.6 16.3 14.5 15.5 8.9 10.1 11.3 16.9 23.0 13.6 10.8 17.9 3.5 2.5 0.3 4.6 3.0 4.8 5.5 5.1 4.9 4.3 4.2 5.5 6.2 0.0 7.5 2.9 3.7 4.1 2.7 15.4 14.6 26.7 25.1 13.6 14.7 17.6 11.1 14.9 16.2 11.9 9.9 6.0 5.4 10.4 19.7 12.3 5.1 37.5 34.2 8.7 15.7 11.2 1.7 10.8 1.7 14.3 5.0 0.0 8.7 9.4 10.1 5.8 22.1 11.0 9.3 17.5 8.6 11.1 14.0 1.8 13.3 12.3 3.3 7.2 12.6 9.4 12.3 8.2 17.3 12.7 18.1 6.5 7.2 26.5 34.0 8.4 8.0 16.2 10.9 3.8 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390431-6394998 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease mutation, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 41.6;fHDF/TERT166: 41.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2000000 "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 14.7 21.4 12.4 10.9 18.7 5.4 10.7 17.2 32.4 14.5 17.4 30.6 15.7 14.3 12.2 15.0 11.6 7.9 18.5 26.8 14.5 13.2 47.1 77.5 17.1 10.7 17.4 15.9 12.9 19.9 35.4 23.8 23.1 21.6 17.6 12.9 23.3 21.5 18.5 20.9 19.7 15.8 14.9 17.8 11.7 13.3 7.4 14.1 18.8 20.2 10.3 11.8 12.5 11.4 3.2 1.8 3.4 2.7 6.8 11.4 3.1 4.6 3.7 2.8 7.6 41.6 21.7 5.0 17.6 27.3 8.0 9.7 6.4 3.3 1.2 8.2 41.0 17.4 1.9 2.4 3.6 3.8 5.9 2.8 1.4 6.0 1.7 18.6 1.0 11.0 28.6 6.9 7.4 5.0 29.6 17.6 0.5 2.5 8.8 17.1 4.7 0.0 1.8 1.1 6.5 6.6 0.3 1.6 1.9 6.9 1.7 4.9 2.8 7.9 5.5 10.8 3.8 2.1 1.9 15.2 29.9 3.2 17.3 4.1 11.3 12.0 0.9 27.7 3.0 13.3 1.8 2.7 3.4 6.9 2.1 5.6 1.6 5.9 5.5 1.4 3.2 11.3 11.4 2.7 6.8 0.6 1.8 4.8 3.1 12.4 18.7 17.2 32.4 14.5 13.2 17.4 15.9 21.6 14.1 23.8 15.6 18.0 17.3 7.0 11.9 31.1 22.9 2.7 9.1 24.4 23.6 33.4 10.0 42.6 42.2 13.5 58.4 0.0 33.0 11.7 31.4 37.7 10.4 72.3 30.5 19.1 22.8 27.6 12.7 155.2 10.6 8.6 52.3 4.6 17.5 16.4 24.7 17.5 12.7 60.8 4.9 0.0 24.5 1.2 1.8 6.9 28.7 20.3 10.9 12.0 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440763-109443919 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 14 "Early spermatids: 151.6;Late spermatids: 248.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favorable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favorable (1.70e-4)" 6.0 6.8 4.2 20.2 4.9 8.5 8.5 5.4 6.4 9.0 12.6 9.8 16.4 10.5 6.1 16.0 17.2 17.4 12.6 5.1 4.9 3.7 10.2 7.8 8.4 9.4 4.7 4.2 6.7 15.5 17.9 8.8 19.5 4.8 10.1 10.2 8.4 16.6 11.9 3.3 16.9 15.4 7.8 4.3 10.1 11.1 35.1 4.7 18.3 10.5 13.5 23.0 6.3 10.1 18.3 13.4 9.3 7.8 6.2 8.0 5.3 8.9 10.4 5.5 8.6 9.7 5.3 18.3 3.0 11.2 7.6 7.2 9.8 7.3 4.9 6.4 6.4 16.0 11.5 5.5 13.2 4.6 6.2 14.2 5.7 10.7 6.0 8.1 6.2 6.7 5.6 15.3 6.7 13.3 8.5 6.9 8.7 11.0 8.7 3.7 12.9 10.0 13.5 1.5 11.9 5.0 7.1 2.6 5.3 13.7 15.3 7.2 6.0 5.7 17.9 13.5 4.6 5.7 12.0 4.4 3.4 4.9 2.7 11.2 5.9 1.5 3.1 6.6 6.0 6.0 5.7 7.8 9.3 6.6 7.5 7.3 12.8 7.4 8.0 10.2 18.3 5.6 5.7 2.3 6.2 6.6 13.4 7.2 5.3 4.2 4.9 5.4 6.4 4.9 3.7 4.7 4.2 4.8 4.7 11.9 7.4 4.2 8.5 8.8 1.3 2.0 12.7 58.9 7.9 12.2 3.9 8.2 1.7 14.7 151.6 3.8 27.2 0.0 17.1 16.1 6.0 12.7 0.0 3.2 8.5 0.0 8.1 4.3 6.6 248.2 8.6 10.8 8.5 11.8 21.2 2.3 13.7 24.6 8.5 7.9 5.2 12.9 2.8 36.6 10.6 16.3 14.2 4.9 13.8 13.7 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358325-68448688 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 44.5;intestine: 46.4;lymphoid tissue: 73.0" "Cell type enriched" "Detected in many" 6 "Horizontal cells: 284.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "plasmacytoid DC: 44.5" "Lineage enriched" "Detected in many" 7 "dendritic cells: 44.5" "Cell line enhanced" "Detected in some" "HMC-1: 9.6;MOLT-4: 13.6;RPMI-8226: 11.3;SCLC-21H: 13.1" "Region enhanced" "Detected in many" "basal ganglia: 103.1" "Low region specificity" "Detected in all" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 3.5 2.3 6.0 3.1 18.3 1.8 1.6 9.4 15.4 1.0 9.6 2.5 0.0 46.4 1.7 0.7 1.8 2.7 17.2 1.2 8.7 3.6 0.9 3.8 2.1 3.5 2.5 5.0 2.7 1.9 0.7 10.7 0.8 3.9 2.2 5.8 4.3 2.2 0.9 1.8 8.1 42.7 1.2 1.4 3.0 18.6 4.2 4.4 73.0 1.3 1.3 4.3 1.6 1.2 0.6 44.5 6.1 0.0 0.0 0.7 0.3 0.3 0.7 0.3 0.1 0.0 0.0 5.3 0.4 0.0 0.4 0.1 2.9 0.9 0.4 0.5 0.2 0.2 1.1 0.0 0.0 0.1 0.3 0.7 0.1 2.1 0.3 0.0 0.0 9.6 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.8 0.3 0.3 0.2 13.6 2.6 0.6 4.6 0.1 0.6 0.2 11.3 0.0 0.1 13.1 2.6 0.4 1.5 0.6 0.3 1.0 0.9 0.0 0.4 0.8 1.4 0.1 2.2 1.1 0.2 0.2 0.9 0.2 1.0 0.0 6.1 0.7 0.0 0.1 0.6 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 44.5 0.5 0.3 6.0 18.3 9.4 15.4 8.7 3.6 2.5 5.0 3.9 4.4 3.0 0.6 0.0 1.4 0.1 39.5 2.5 5.1 16.0 1.2 0.0 0.0 0.0 0.0 0.9 6.0 0.0 51.1 0.0 0.8 0.2 0.3 3.7 0.0 5.0 0.2 284.4 24.8 0.0 0.6 13.0 14.1 0.0 0.0 0.0 25.6 0.8 1.2 43.0 43.2 0.0 3.3 0.0 0.0 5.4 0.3 0.9 0.0 5.0 18.7 4.7 SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA NA "Nuclear membrane" Cytosol "HPA046279: AB_2679611, HPA049426: AB_2680762" "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.73e-4)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" 13.2 16.1 12.4 17.1 20.7 39.1 14.8 22.1 25.1 19.9 15.8 31.4 15.3 15.5 22.5 14.1 19.3 19.5 12.7 13.4 13.2 16.0 14.3 18.5 14.7 20.5 21.3 12.2 22.2 22.2 24.1 31.2 24.3 19.5 16.3 16.7 17.7 17.1 15.2 17.0 17.5 15.2 18.3 16.0 16.4 14.5 23.6 21.6 27.9 22.8 19.6 27.1 16.9 16.6 10.5 9.8 14.5 11.4 11.7 15.2 9.7 32.0 15.8 20.0 14.8 10.3 7.6 26.1 17.1 12.7 25.2 21.1 45.8 16.5 20.9 15.2 17.1 14.4 18.2 25.5 22.6 17.5 27.7 24.7 23.5 17.0 36.3 8.8 26.2 15.0 8.8 15.2 28.3 11.3 9.3 14.5 20.9 29.2 17.0 14.1 17.3 27.4 13.2 30.7 13.7 21.1 29.1 15.2 22.7 10.7 15.2 27.8 15.6 16.8 20.6 7.5 11.6 14.0 11.5 11.2 21.6 21.0 14.1 20.0 14.8 16.6 28.1 19.5 15.0 15.3 1.8 9.3 14.5 13.9 11.4 15.2 9.5 10.4 12.4 9.8 10.5 10.2 11.4 4.5 11.7 8.0 6.4 9.4 9.7 12.4 20.7 22.1 25.1 13.2 16.0 21.3 12.2 19.5 21.6 3.0 9.9 10.2 9.1 13.4 20.0 3.2 5.1 6.7 6.8 7.0 11.8 19.8 8.3 8.1 17.4 7.4 7.1 0.0 10.5 21.1 10.3 8.6 5.8 13.5 12.1 14.3 12.6 9.8 9.4 32.6 13.6 6.5 15.1 5.4 12.5 7.8 11.0 9.1 17.3 5.6 15.1 0.0 8.0 24.0 22.0 18.1 13.0 12.8 12.1 7.9 SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274336-96305515 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029321 Approved Supported Nucleoplasm NA NA 6600 Nucleoplasm "HPA029321: AB_10604096" "unprognostic (2.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (2.48e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" 26.6 25.2 18.4 28.4 21.9 32.0 26.1 37.2 25.8 24.4 23.6 23.7 20.6 18.4 34.7 22.6 23.4 26.5 22.0 22.0 19.7 12.3 19.0 25.8 22.7 25.1 16.6 18.9 39.3 22.7 49.4 25.2 33.7 18.9 21.3 22.0 25.5 28.3 23.0 39.7 25.3 27.6 28.3 15.8 25.2 23.4 34.3 19.5 57.3 25.3 21.3 31.2 33.7 24.0 8.5 7.7 15.3 7.5 9.1 12.6 6.0 23.1 26.3 35.4 26.5 16.5 14.6 33.3 16.0 19.6 29.4 28.1 47.9 17.0 40.4 25.4 20.5 44.7 18.4 64.9 21.8 30.4 21.8 34.3 51.6 41.9 25.9 10.7 39.5 22.7 15.1 13.6 33.4 28.4 15.5 23.8 23.9 45.1 27.2 16.9 20.2 37.0 11.8 46.0 19.1 25.5 43.8 34.3 25.3 11.4 34.3 39.3 37.4 26.0 22.3 16.6 42.5 21.3 24.7 20.6 24.5 29.7 24.8 23.1 25.3 29.8 50.3 16.6 26.4 26.1 15.3 5.6 7.5 10.1 7.0 12.2 7.8 7.8 12.6 7.3 8.5 7.6 9.3 6.2 9.1 7.5 7.7 8.5 6.0 18.4 21.9 37.2 25.8 19.7 12.3 16.6 18.9 18.9 19.5 41.7 51.7 49.6 23.8 26.3 74.3 30.5 71.4 40.2 45.5 48.8 98.2 36.0 5.0 36.2 22.5 41.7 37.6 23.3 40.2 31.2 30.8 30.4 24.3 42.9 30.8 82.6 44.9 33.2 27.5 10.6 53.2 32.3 16.9 37.9 40.6 92.0 36.3 35.1 51.9 14.6 128.6 64.7 38.7 86.5 54.9 28.9 37.3 66.0 41.3 27.3 SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009729 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 15.1" "Cell type enriched" "Detected in single" 29 "Early spermatids: 2.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;JURKAT: 1.3;NB-4: 3.9;U-266/70: 1.2;U-266/84: 2.1" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" NA NA "HPA044747: AB_2679071, HPA047149: AB_2679955" 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.8 0.0 0.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.5 0.4 0.3 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 0.0 15.1 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.3 3.9 0.9 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.5 1.1 0.0 0.0 0.4 0.0 0.7 0.0 1.2 2.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130657-48132613 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 18.3" "Cell type enriched" "Detected in single" 12 "Early spermatids: 1.2" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "T-reg: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" NA NA "HPA044747: AB_2679071, HPA047149: AB_2679955" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 19.6" "Group enriched" "Detected in some" 58 "Early spermatids: 169.9;Late spermatids: 83.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.0;SuSa: 1.5" "Not detected" "Not detected" HPA017984 Enhanced NA NA "HPA017984: AB_1857413" "unprognostic (2.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 169.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 83.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 1.1 0.0 2.2 0.0 0.0 0.0 SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063547-32157637 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA017311: AB_1857415" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.26e-2)" "unprognostic (2.35e-2)" "unprognostic (7.39e-2)" "unprognostic (5.98e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.13e-1)" 12.7 9.6 18.4 14.8 16.4 13.4 9.8 21.1 21.9 14.7 12.7 15.1 12.5 11.5 12.3 8.7 11.1 10.4 10.2 6.2 20.2 18.5 9.4 14.6 9.7 18.9 20.6 10.0 15.1 10.9 11.8 12.3 11.5 17.5 10.3 12.0 6.8 9.3 13.7 15.4 11.5 17.6 11.6 27.0 15.5 9.7 14.4 14.6 21.5 13.4 6.2 13.8 11.3 10.1 5.0 7.1 9.5 9.0 6.6 7.6 4.3 10.8 7.8 12.9 12.6 8.1 9.6 11.6 6.0 8.9 6.3 5.7 10.6 9.5 19.0 5.6 8.3 9.3 7.7 12.7 6.1 7.8 12.7 7.6 20.8 4.2 12.9 7.4 14.5 14.7 5.3 8.1 8.1 7.7 7.7 13.9 6.2 17.0 6.4 6.9 4.6 23.3 12.2 13.4 12.1 4.6 12.4 18.1 12.3 8.6 6.8 18.3 19.7 10.2 8.7 10.0 11.0 5.6 10.0 12.1 7.0 10.8 6.2 7.0 9.7 18.0 15.4 7.6 12.6 8.4 3.4 6.3 6.7 3.6 9.0 5.2 5.0 5.8 5.6 7.1 3.9 5.9 6.0 9.5 6.6 6.3 3.2 7.6 4.3 18.4 16.4 21.1 15.8 20.2 18.5 20.6 10.0 17.5 14.6 8.9 4.1 4.2 5.3 8.5 14.5 7.5 7.6 13.4 6.8 5.2 21.6 7.6 0.0 5.6 2.5 8.7 9.7 0.0 7.0 6.2 5.0 7.3 9.3 10.9 8.8 9.5 10.4 6.2 14.6 6.4 8.1 16.6 1.7 8.2 10.1 8.0 8.4 8.4 9.6 6.5 14.3 0.0 8.1 15.4 22.2 11.4 6.8 7.5 8.4 5.5 SSH1 KIAA1298 ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778192-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 7.3 7.8 8.5 7.4 8.1 10.6 9.3 20.3 8.8 7.4 8.5 6.8 13.1 4.4 9.8 7.9 7.6 8.2 8.3 10.1 8.0 6.9 5.8 7.4 10.1 8.7 7.7 5.2 7.9 8.0 9.7 6.8 7.8 8.4 6.5 6.5 15.0 5.9 8.0 21.4 7.1 6.5 10.4 8.1 8.6 7.1 5.2 6.6 2.0 7.0 7.9 6.6 10.0 13.3 1.8 2.0 5.7 4.0 2.1 2.9 1.2 5.1 6.8 4.5 3.5 8.5 7.3 4.0 6.6 14.2 6.1 5.4 3.4 2.5 2.4 4.7 15.5 10.4 5.1 2.7 11.2 5.0 5.0 2.6 5.7 3.1 2.1 4.6 2.9 15.2 10.0 3.8 5.5 12.3 15.1 5.6 3.0 1.3 2.0 15.9 2.9 3.3 4.2 3.1 2.0 5.5 2.4 5.3 3.2 2.4 9.2 3.3 4.5 5.8 1.6 12.8 6.5 2.1 2.6 4.4 10.9 4.7 6.5 3.8 3.9 3.5 3.0 5.7 2.4 34.4 4.2 2.4 4.8 2.9 4.0 2.7 1.6 1.5 2.5 1.6 1.8 1.4 1.6 5.7 2.1 3.2 2.0 1.7 1.2 8.5 8.1 20.3 8.8 8.0 6.9 7.7 5.2 8.4 6.6 8.9 17.3 4.7 15.4 8.4 10.6 21.2 12.7 8.1 14.8 14.0 15.7 4.7 5.0 7.7 1.6 37.5 3.5 0.0 7.0 3.7 10.3 7.2 19.7 13.4 11.2 11.1 5.2 25.8 24.7 2.6 6.1 17.8 11.8 43.3 6.6 8.8 10.1 0.0 12.0 4.9 20.7 6.5 17.6 1.1 6.6 7.9 1.9 15.4 5.7 12.2 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" 4 "Kupffer cells: 119.4;Late spermatids: 117.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain NA NA "CAB017189: , HPA057099: AB_2683336" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 12.3 7.7 15.8 19.0 16.0 43.1 7.9 23.9 18.0 6.8 10.6 17.5 8.8 7.4 6.1 8.5 9.4 6.5 7.9 12.0 12.9 8.4 10.8 9.8 15.1 20.9 13.6 12.4 3.7 11.8 6.4 6.5 8.8 10.6 5.1 10.0 7.9 8.6 11.6 59.6 10.5 14.5 6.9 12.6 21.3 10.3 26.1 15.2 22.7 10.7 9.5 19.9 7.8 6.5 7.9 4.0 37.8 4.5 1.4 5.9 1.8 12.0 9.8 6.3 5.4 17.4 11.9 3.7 6.0 6.8 9.9 10.5 5.3 4.5 10.0 9.6 7.1 6.6 14.0 7.7 8.7 11.5 3.5 13.7 6.9 10.0 7.7 8.2 7.4 15.0 14.0 5.8 10.5 7.0 4.9 22.6 17.8 4.9 7.8 6.9 3.4 34.8 7.5 4.7 4.6 5.1 16.7 15.9 17.5 17.1 9.4 10.6 11.8 8.7 9.7 17.3 8.9 6.4 7.8 12.4 6.7 13.8 11.8 7.2 11.9 7.8 25.0 8.0 5.9 6.2 11.0 3.8 37.8 3.5 4.5 2.9 7.5 4.4 3.5 4.0 7.9 4.1 3.0 9.6 1.4 3.8 2.6 5.9 1.8 15.8 16.0 23.9 18.0 12.9 8.4 13.6 12.4 10.6 15.2 8.9 36.3 54.0 11.9 35.1 12.4 22.6 10.2 12.0 13.6 15.7 25.5 18.7 21.6 14.9 77.6 21.9 36.6 0.0 30.8 18.1 14.6 14.0 11.6 24.1 20.1 19.1 34.0 22.1 119.4 117.3 11.2 43.4 33.7 19.0 31.7 6.8 31.7 27.4 7.8 39.3 20.1 6.5 14.4 41.9 16.4 31.7 15.2 40.3 22.3 20.4 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303448-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.8;eosinophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.8" "Cell line enhanced" "Detected in many" "HaCaT: 23.8;RT4: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 8.6 5.5 5.6 6.8 9.7 8.1 13.5 17.8 9.4 14.6 15.9 15.4 19.5 12.4 10.1 10.6 27.0 15.2 20.5 7.7 6.0 6.1 10.3 7.5 9.0 3.5 13.6 5.4 17.1 12.0 11.3 7.4 20.0 8.5 19.8 9.2 11.9 19.1 30.5 5.2 18.2 13.6 13.1 9.3 6.9 13.9 4.2 9.7 0.8 12.8 14.0 13.2 33.3 18.6 0.3 1.6 10.8 2.3 1.5 2.2 1.0 6.2 6.7 0.1 0.2 4.8 4.9 7.4 4.1 5.4 2.1 2.0 7.3 16.5 0.3 12.6 3.7 4.5 23.8 2.2 17.2 1.2 1.3 2.5 1.6 10.9 2.9 3.3 0.3 6.1 4.3 15.9 3.1 3.3 5.0 2.4 0.1 0.0 0.6 2.5 21.0 0.2 3.0 1.5 17.0 5.4 7.7 0.2 1.1 7.0 36.0 1.4 2.2 9.5 14.1 4.4 2.6 19.8 5.2 3.9 1.7 3.7 4.8 1.1 0.7 0.3 0.2 4.9 2.7 1.6 10.8 1.4 10.5 2.2 2.3 1.7 0.3 2.1 1.8 1.6 0.2 0.8 0.9 4.5 1.5 1.1 1.1 1.8 1.0 5.6 9.7 17.8 9.4 6.0 6.1 13.6 5.4 8.5 9.7 3.0 5.4 0.0 20.7 6.3 1.1 3.4 15.3 8.1 10.3 15.7 0.0 12.6 3.3 16.4 0.0 3.9 17.2 0.0 19.0 20.2 6.2 13.1 3.5 4.3 6.8 1.6 3.5 4.3 8.6 0.0 12.0 2.9 8.5 12.6 14.7 4.6 16.4 17.5 11.3 6.3 0.4 0.0 8.3 0.3 0.0 9.2 13.2 4.3 18.5 22.9 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574869 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 520.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol No No "Nucleoplasm, Cytosol" "HPA069290: AB_2686108, HPA070604: AB_2686285" "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 44.1 32.5 48.0 33.6 51.5 29.3 73.9 42.3 51.5 37.2 40.1 25.4 39.3 41.3 32.6 51.8 45.7 46.2 35.3 44.4 40.7 42.5 38.0 50.9 37.5 49.0 39.4 39.0 38.0 61.8 33.9 39.9 35.8 36.9 33.9 35.9 34.1 54.2 35.8 107.1 36.9 40.8 35.4 35.0 41.7 38.5 28.0 28.4 37.0 50.9 45.3 36.3 30.8 42.2 35.5 30.1 62.0 28.8 20.7 46.5 28.1 41.4 26.6 19.2 29.6 33.1 32.0 19.7 36.1 28.2 31.5 32.9 24.9 48.2 42.2 19.8 28.4 30.8 32.4 31.0 29.7 30.8 35.1 36.6 26.5 23.3 39.3 37.5 33.5 23.2 28.5 25.1 33.7 32.2 26.5 29.4 25.7 45.8 32.7 24.9 36.9 38.3 53.8 33.6 40.9 40.4 30.5 31.0 59.0 34.5 12.8 35.6 24.4 24.4 62.7 106.5 34.0 32.7 29.2 22.4 30.4 19.3 34.2 30.9 39.9 47.9 52.7 31.8 53.4 14.7 37.1 28.3 53.6 25.9 28.8 31.9 35.5 34.4 30.7 30.1 33.1 42.2 34.1 62.0 20.7 25.4 19.0 46.5 28.1 48.0 51.5 42.3 51.5 40.7 42.5 39.4 39.0 36.9 28.4 26.8 71.4 136.9 121.9 165.4 98.0 80.5 117.2 36.1 37.5 96.0 19.6 178.0 247.1 62.6 202.0 95.1 177.2 0.0 92.6 189.0 93.0 151.4 60.0 123.8 125.1 106.5 136.4 90.9 152.3 520.2 97.0 118.3 158.6 91.0 137.9 96.8 78.9 168.6 80.6 258.7 57.5 58.2 97.3 81.2 147.4 192.6 205.2 116.7 134.0 129.8 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "Suppression of tumorigenicity 14" Q9Y5Y6 11 130159562-130210376 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease mutation, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 94.1" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 295.9;Mucus-secreting cells: 176.7;Paneth cells: 178.5;Urothelial cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 18.2" "Lineage enriched" "Detected in many" 5 "dendritic cells: 18.2" "Cell line enhanced" "Detected in some" "CACO-2: 36.0;CAPAN-2: 72.5;HaCaT: 50.8;OE19: 38.5;RPMI-8226: 47.5;SK-BR-3: 33.6;T-47d: 50.8;U-698: 34.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA047014 Approved Nucleoplasm,Vesicles NA NA 220000 "Nucleoplasm, Vesicles" "HPA047014: AB_2679902" "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 10.1 1.8 0.7 21.9 1.8 0.5 5.5 0.8 1.4 8.9 48.6 0.5 23.8 33.8 2.8 16.9 38.9 9.7 32.4 1.1 0.5 0.5 30.5 3.2 9.5 7.5 1.8 0.6 3.6 34.3 8.4 9.5 12.7 1.5 12.1 15.4 0.7 25.1 15.8 0.7 17.8 94.1 1.2 1.8 4.0 16.7 2.1 1.5 5.2 24.0 20.1 28.4 8.3 14.9 3.8 18.2 2.3 2.7 0.0 0.1 0.8 26.4 0.0 0.0 0.1 0.0 0.0 14.4 0.0 0.0 0.0 0.0 36.0 72.5 26.1 2.7 0.0 0.0 50.8 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.1 0.2 38.5 0.1 0.0 0.0 47.5 4.7 21.7 2.9 0.0 0.2 33.6 0.0 0.2 50.8 5.1 0.0 0.0 0.4 0.1 0.1 0.0 0.0 34.6 0.0 8.0 0.0 0.0 2.7 2.3 0.0 1.5 0.1 3.8 0.0 0.0 4.5 2.3 0.0 0.0 0.3 0.0 0.2 18.2 0.0 0.8 0.7 1.8 0.8 1.4 0.5 0.5 1.8 0.6 1.5 1.5 29.8 25.8 9.3 31.0 36.4 0.0 0.8 38.2 17.4 20.5 59.3 0.0 40.3 3.3 108.8 27.9 0.4 295.9 0.0 80.1 11.6 2.6 89.5 11.5 1.9 60.1 0.0 118.5 0.0 25.4 11.5 1.7 19.0 6.8 8.2 176.7 0.0 114.4 178.5 0.7 10.5 0.0 6.5 1.4 0.2 0.1 38.3 33.2 1.3 155.8 230.3 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7219456-7354810 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 258.8" "Cell type enhanced" "Detected in many" 13 "Cytotrophoblasts: 34.3;Syncytiotrophoblasts: 78.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 20.3;RPMI-8226: 25.9;U-266/70: 43.0;U-698: 18.0" HPA002904 Enhanced NA NA "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 10.3 2.2 3.0 2.2 3.9 0.0 4.1 2.3 9.0 3.4 3.5 2.3 2.2 0.8 2.4 2.2 2.2 2.6 4.1 3.6 3.9 4.0 2.5 4.7 5.0 2.2 3.8 2.4 2.4 2.2 1.6 2.2 258.8 2.4 2.9 3.0 2.3 2.2 3.3 4.0 2.3 2.4 3.8 2.4 2.2 6.7 2.2 2.3 2.2 2.4 2.2 2.2 4.9 2.7 0.9 1.9 1.9 4.7 1.0 0.7 1.0 4.1 1.3 2.8 0.9 20.3 10.5 15.0 8.4 3.0 2.3 2.1 7.4 3.9 7.7 1.6 6.1 1.8 1.0 1.6 1.4 2.3 0.6 3.2 0.4 4.7 2.1 1.1 1.1 4.4 3.4 0.2 1.4 0.8 1.5 3.4 0.6 0.4 8.1 6.0 0.9 0.6 1.0 1.0 0.0 1.9 1.1 1.6 25.9 5.7 6.0 2.0 1.7 1.7 3.0 0.9 4.8 1.3 0.4 6.0 9.1 0.5 11.6 1.3 43.0 0.0 18.0 2.1 0.9 2.4 0.0 3.2 0.6 0.5 4.7 0.2 0.6 0.2 0.3 1.9 0.9 0.1 0.5 1.9 1.0 2.5 0.3 0.7 1.0 3.0 3.9 2.3 9.0 3.9 4.0 3.8 2.4 2.4 2.3 11.9 2.1 1.5 1.7 0.8 3.1 5.0 2.5 0.0 1.2 1.8 0.0 34.3 0.0 6.9 0.1 4.3 4.1 0.0 17.1 18.7 4.1 7.6 6.9 7.4 6.6 1.6 3.5 2.5 5.9 0.0 2.6 2.7 1.7 2.8 2.3 3.1 8.7 7.4 6.3 1.4 0.8 0.0 4.7 0.0 1.4 0.9 78.6 0.0 2.2 7.4 SUPV3L1 SUV3 ENSG00000156502 "Suv3 like RNA helicase" Q8IYB8 10 69180232-69209099 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038380, HPA038405" Supported Supported Mitochondria NA NA Mitochondria "HPA038380: AB_2675983, HPA038405: AB_10675797" "unprognostic (4.70e-2)" "unprognostic (1.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.74e-2)" "unprognostic (3.32e-2)" "unprognostic (1.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (9.47e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-3)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" 12.8 17.0 11.1 12.6 17.3 26.1 17.7 21.9 19.9 10.8 14.4 12.6 7.8 11.2 13.5 12.4 13.2 11.9 12.6 19.2 12.0 11.3 16.4 22.2 9.6 15.2 9.9 13.1 15.8 18.2 15.4 14.7 10.9 16.1 11.4 16.7 12.4 11.8 13.9 31.1 15.6 12.5 13.9 9.9 15.5 13.0 26.6 9.9 12.7 14.1 13.4 14.8 12.4 11.6 10.1 7.3 5.6 7.7 7.4 13.7 6.2 11.5 8.1 7.3 22.3 8.2 7.0 9.6 7.2 11.2 14.6 13.8 20.8 9.8 20.8 5.9 7.2 10.4 13.3 17.4 11.2 14.1 8.7 13.7 9.1 6.4 10.9 20.7 21.6 6.9 8.8 14.2 13.4 30.8 10.0 8.4 13.3 23.7 10.9 8.0 7.5 13.1 13.4 8.7 11.0 44.4 12.1 10.3 9.1 6.6 5.6 10.4 7.9 9.9 20.8 18.9 8.4 6.4 9.5 5.2 5.8 10.5 8.8 13.9 8.6 10.0 19.5 9.6 22.9 3.6 5.6 5.2 4.3 12.3 7.7 13.7 10.1 8.9 10.5 7.3 8.3 9.9 10.6 0.9 7.4 5.2 4.0 8.7 6.2 11.1 17.3 21.9 19.9 12.0 11.3 9.9 13.1 16.1 9.9 6.0 9.0 10.0 9.6 21.2 21.5 19.6 10.2 14.7 13.6 7.0 3.9 15.0 10.0 10.0 8.2 8.5 7.8 0.0 7.4 9.9 9.7 6.9 7.0 10.9 8.7 11.1 8.6 6.7 3.1 3.4 6.4 5.6 5.0 5.4 8.6 10.8 8.0 9.0 8.5 12.2 11.3 6.5 13.4 28.6 24.5 19.4 18.8 15.8 11.8 9.5 SYNJ1 "INPP5G, PARK20" ENSG00000159082 "Synaptojanin 1" O43426 21 32628759-32728048 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, RNA-binding" "Disease mutation, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 43.2;Rod photoreceptor cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011916 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Nucleoplasm, Cytosol" Centrosome "HPA011916: AB_1857692" "unprognostic (6.84e-2)" "unprognostic (8.64e-2)" "unprognostic (5.76e-2)" "unprognostic (6.44e-2)" "unprognostic (1.27e-1)" "prognostic favorable (4.43e-4)" "unprognostic (1.45e-1)" "unprognostic (3.73e-3)" "unprognostic (1.63e-1)" "unprognostic (6.22e-3)" "unprognostic (1.84e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.28e-1)" "unprognostic (6.36e-2)" "unprognostic (5.97e-2)" "unprognostic (1.79e-1)" "unprognostic (2.92e-1)" 5.5 6.8 13.6 5.0 25.9 20.6 4.2 19.5 39.0 4.8 4.8 6.5 0.8 3.9 4.6 5.3 3.9 4.0 5.2 5.2 18.3 18.2 7.4 5.5 6.5 5.7 16.6 18.4 4.6 4.5 10.6 10.9 9.3 33.5 3.6 5.5 7.0 3.8 4.0 4.4 5.0 4.6 5.0 7.3 6.0 4.2 9.0 5.7 3.2 6.8 1.5 4.8 4.7 3.3 0.4 3.1 11.5 6.0 0.5 3.0 1.1 5.6 2.8 5.2 5.7 9.1 7.3 10.6 11.7 6.7 7.2 6.0 6.4 2.6 2.1 3.9 7.0 9.6 5.3 9.3 6.8 8.6 6.7 8.9 14.1 9.2 3.5 4.9 5.8 12.5 4.1 5.1 12.4 6.3 5.9 11.2 7.5 10.5 12.1 9.2 5.7 5.4 4.8 3.7 6.2 6.5 5.9 11.3 7.4 7.6 4.1 5.9 4.6 14.4 9.2 5.6 7.4 7.9 7.5 12.3 11.1 5.5 8.9 6.4 6.3 7.3 4.4 8.4 11.0 8.8 3.7 3.4 7.9 1.6 6.0 2.7 0.2 2.4 2.6 3.1 0.4 2.9 2.8 11.5 0.5 5.3 1.6 3.0 1.1 13.6 25.9 19.5 28.7 18.3 18.2 16.6 18.4 33.5 5.7 6.0 4.8 2.9 2.0 4.2 21.5 7.3 5.1 4.0 2.3 1.8 43.2 13.3 5.0 1.6 14.8 7.9 4.9 0.0 1.2 7.9 3.7 2.2 3.5 3.6 8.6 9.5 2.9 8.6 19.0 8.6 2.6 7.5 1.7 1.0 2.7 19.5 2.1 3.5 4.2 5.0 40.7 6.5 3.4 16.4 10.9 2.9 31.8 6.9 4.0 4.1 SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981887-158099176 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 62.0" "Cell type enhanced" "Detected in many" 8 "Pancreatic endocrine cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 46.3;TIME: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol NA NA Microtubules Cytosol "HPA031575: AB_10604101" "prognostic unfavorable (2.63e-4)" "unprognostic (1.94e-2)" "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.48e-2)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.06e-2)" "unprognostic (2.91e-1)" "unprognostic (7.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.02e-6)" "unprognostic (1.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.75e-1)" "unprognostic (9.45e-2)" 2.8 3.9 12.2 4.9 25.1 15.3 6.7 3.0 18.7 3.9 8.7 50.5 3.7 5.8 5.2 9.4 6.0 4.6 8.0 8.5 17.8 10.9 3.2 4.0 2.8 4.4 46.8 8.8 2.9 6.6 1.1 2.9 2.6 33.0 5.3 8.9 1.4 13.5 5.1 4.3 3.1 5.6 6.6 62.0 3.3 7.0 6.5 24.4 3.0 4.4 1.4 5.3 5.9 3.0 3.2 1.1 9.3 1.3 2.4 3.8 0.8 5.4 19.2 1.6 2.5 1.2 4.0 8.5 10.1 20.5 12.1 14.3 9.8 4.6 0.1 6.9 19.4 46.3 5.2 3.4 6.3 14.1 7.6 3.2 10.6 10.0 10.3 2.3 3.7 11.6 2.0 3.4 18.4 4.3 16.4 21.0 5.6 8.1 2.4 5.5 2.5 4.6 4.1 1.8 17.1 10.7 2.0 6.6 4.9 4.0 6.3 12.2 0.7 7.8 4.9 1.9 6.3 3.8 2.3 37.1 9.2 9.4 21.2 12.2 1.0 2.6 0.2 17.2 5.9 6.3 4.5 1.3 1.1 1.9 0.6 3.8 1.9 2.6 1.7 1.1 3.2 2.2 1.7 9.3 2.4 0.8 1.1 2.1 0.8 12.2 25.1 3.0 18.7 17.8 10.9 46.8 8.8 33.0 24.4 3.0 3.5 2.7 16.6 19.3 0.0 10.4 10.2 10.7 6.8 17.4 0.0 5.3 3.3 36.4 22.7 10.5 15.3 0.0 30.7 4.2 14.6 30.3 4.7 4.5 1.9 0.0 16.7 7.4 3.4 37.2 1.1 4.6 10.1 10.8 14.5 1.5 88.4 3.5 6.0 1.4 0.4 0.0 6.6 0.7 1.1 15.1 13.3 5.3 14.5 32.4 TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965804-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA052263: AB_2681777" "unprognostic (3.15e-1)" "unprognostic (1.36e-1)" "unprognostic (9.89e-3)" "unprognostic (6.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (1.56e-2)" "prognostic unfavorable (6.90e-5)" "unprognostic (5.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.90e-10)" "unprognostic (3.68e-1)" "unprognostic (2.90e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" 12.3 16.6 7.0 17.9 11.1 15.9 12.8 10.7 13.4 17.7 14.7 10.0 11.3 11.0 15.8 17.8 23.8 12.4 12.8 12.0 7.7 6.9 13.4 17.4 13.7 19.7 8.7 7.9 14.4 13.2 11.0 21.0 27.9 10.8 13.0 16.8 10.9 13.2 11.3 11.1 16.3 18.7 17.8 8.8 19.8 13.1 5.8 8.1 33.4 12.4 15.3 19.6 13.3 14.7 18.9 41.4 18.8 24.3 14.2 13.6 7.2 13.3 6.8 21.5 12.5 5.3 4.8 21.7 10.1 4.2 14.2 8.0 11.6 6.1 31.6 6.2 8.4 2.3 9.0 25.6 11.9 11.2 12.9 20.7 24.8 10.3 5.2 5.0 30.7 18.8 5.6 15.9 10.5 8.5 8.7 13.9 18.7 27.7 5.3 6.8 14.0 34.3 17.3 26.0 9.9 10.9 35.4 11.1 11.2 15.5 19.8 28.3 19.6 12.3 14.5 9.0 13.2 23.2 16.6 8.4 4.4 7.3 4.7 12.0 11.6 15.3 27.1 4.9 16.6 8.5 18.5 24.3 18.8 13.6 16.3 10.3 17.7 13.0 11.2 14.9 18.9 13.5 12.1 16.0 14.2 15.9 41.4 12.6 7.2 7.0 11.1 10.7 13.4 7.7 6.9 8.7 7.9 10.8 8.1 35.7 18.4 41.0 33.6 70.2 45.5 23.0 35.7 40.2 40.9 31.4 25.5 58.2 31.5 66.4 3.9 43.9 26.9 23.3 46.9 70.7 38.1 38.3 38.3 30.1 39.3 33.4 78.4 36.2 38.6 2.1 25.3 39.1 15.1 39.7 39.8 23.0 64.5 34.5 28.3 18.0 37.1 45.3 30.7 9.9 25.0 89.8 131.0 39.9 38.9 48.0 TDRD12 "ECAT8, FLJ13072" ENSG00000173809 "Tudor domain containing 12" Q587J7 19 32719753-32829580 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 36.1" "Cell type enhanced" "Detected in some" 18 "Early spermatids: 18.5;Spermatocytes: 43.5;Spermatogonia: 44.9" "Cancer enriched" "Detected in many" 9 "testis cancer: 10.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive CD8 T-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Group enriched" "Detected in some" 30 "HDLM-2: 12.8;NTERA-2: 42.6" "Low region specificity" "Detected in many" NA NA "unprognostic (5.43e-2)" "unprognostic (3.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.87e-7)" "unprognostic (5.44e-2)" "unprognostic (1.78e-1)" "unprognostic (6.79e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.40e-1)" "unprognostic (9.69e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-4)" "unprognostic (2.09e-1)" "unprognostic (4.75e-2)" "unprognostic (3.08e-2)" "unprognostic (2.69e-2)" 0.2 0.7 0.2 0.1 0.4 0.0 0.4 0.2 0.5 0.9 0.3 0.2 0.6 0.0 1.1 8.5 0.2 1.1 0.3 0.3 0.1 0.2 0.9 0.1 0.2 0.8 0.3 0.1 1.8 0.1 0.0 0.2 0.2 0.6 0.2 0.0 0.3 0.2 0.6 0.1 1.7 1.2 0.1 0.1 0.9 0.2 36.1 0.1 0.6 0.9 0.1 0.6 0.5 0.3 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.1 0.6 0.0 0.0 0.9 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 12.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 0.2 0.5 0.1 0.2 0.3 0.1 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.6 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 18.5 0.0 0.0 0.0 0.0 1.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 9.0 2.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.4 0.2 0.3 0.0 0.1 43.5 44.9 0.1 0.2 0.0 0.2 0.0 TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928462-104052667 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "parathyroid gland: 19.9;testis: 48.0" "Group enriched" "Detected in many" 5 "Spermatocytes: 69.1;Spermatogonia: 37.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "classical monocyte: 4.6" "Lineage enriched" "Detected in single" 5 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HDLM-2: 11.1;HeLa: 9.7;HMC-1: 45.2;RPTEC TERT1: 12.3;SK-MEL-30: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (3.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-4)" "unprognostic (1.60e-2)" "unprognostic (4.57e-3)" "unprognostic (8.97e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.41e-2)" 0.4 0.4 0.7 0.4 1.5 1.2 0.5 1.5 1.5 0.3 0.3 0.8 0.6 0.1 0.3 0.3 0.2 0.7 2.1 0.6 0.8 0.7 1.8 0.5 1.0 0.3 0.8 1.3 0.3 0.7 19.9 0.9 0.4 3.4 0.3 0.1 1.8 0.9 1.0 0.1 0.1 0.3 0.4 1.6 2.8 0.6 48.0 0.5 0.2 4.2 0.0 0.8 0.4 0.2 0.0 0.8 0.0 4.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 9.7 0.0 0.0 0.0 45.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 4.1 0.0 0.0 0.3 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.5 1.5 1.5 0.8 0.7 0.8 1.3 3.4 0.5 6.0 1.3 0.0 0.0 0.0 3.1 9.7 0.0 0.0 1.2 0.0 3.9 0.0 1.7 0.6 11.1 0.7 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 1.8 6.4 0.0 0.0 2.4 6.0 0.9 0.2 0.0 0.0 0.0 0.5 0.5 0.0 2.1 1.9 1.7 6.5 0.5 69.1 37.7 0.0 0.0 0.0 0.0 0.0 THEM4 CTMP ENSG00000159445 "Thioesterase superfamily member 4" Q5T1C6 1 151873584-151909808 "Enzymes, Predicted intracellular proteins" "Apoptosis, Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 98.2;Rod photoreceptor cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 30.5" "Low region specificity" "Detected in all" HPA028161 Approved NA NA "HPA028161: AB_10603454" "unprognostic (2.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.15e-3)" "unprognostic (2.23e-2)" "unprognostic (1.07e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (3.02e-2)" "unprognostic (9.25e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-3)" 8.3 15.3 8.4 9.8 11.7 4.9 12.2 19.8 13.2 6.6 8.0 11.3 22.4 8.5 10.3 18.0 6.1 8.5 7.2 9.8 8.7 11.9 19.9 13.4 8.9 15.7 10.8 6.4 9.2 15.9 10.9 21.0 6.3 11.1 8.0 11.6 14.9 9.2 23.1 18.3 6.7 8.1 7.9 10.0 9.2 9.6 10.2 11.8 3.1 11.3 6.4 13.6 11.3 8.3 3.0 5.0 1.8 1.6 6.2 18.6 2.8 3.7 4.3 1.0 3.5 3.7 3.0 3.4 3.1 3.8 4.3 3.5 4.8 3.3 10.2 5.0 4.6 2.0 4.0 2.9 10.0 4.3 10.6 2.0 13.8 6.0 5.5 3.5 15.9 4.5 5.9 4.4 4.5 4.5 3.5 7.2 0.1 17.3 7.8 6.2 6.4 0.0 4.2 18.0 4.5 7.6 0.0 0.8 2.6 5.1 3.7 4.6 8.3 2.2 4.0 30.5 3.7 10.4 6.6 6.2 0.4 3.8 2.9 1.3 12.7 16.4 6.5 6.5 8.7 20.3 1.5 0.6 1.8 6.1 1.6 9.1 3.0 12.7 6.0 2.0 1.5 12.3 8.7 0.4 6.2 0.5 5.0 18.6 2.8 8.4 11.7 19.8 13.2 8.7 11.9 10.8 6.4 11.1 11.8 6.0 13.7 16.1 7.2 4.9 35.0 16.1 12.7 5.3 12.5 14.0 98.2 25.2 34.9 15.2 30.2 12.0 7.0 0.0 16.8 13.9 14.6 5.0 23.1 15.3 11.4 12.7 17.4 21.5 3.1 23.7 15.5 10.4 20.3 9.0 7.0 23.7 12.7 11.4 15.2 21.4 70.5 12.9 10.8 26.5 20.0 3.9 8.6 24.5 12.8 3.5 THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847263-151853697 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skin 1: 59.8;tongue: 24.7" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "MAIT T-cell: 4.2" "Lineage enriched" "Detected in single" 7 "T-cells: 4.2" "Cell line enriched" "Detected in some" 6 "HDLM-2: 39.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "basal ganglia: 20.0" NA NA "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.41e-2)" "unprognostic (2.58e-3)" "unprognostic (9.55e-3)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.86e-3)" "unprognostic (3.07e-3)" "unprognostic (9.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.34e-2)" "unprognostic (1.62e-2)" 0.1 0.6 0.3 0.5 0.2 0.0 1.8 0.2 1.6 3.6 0.1 0.2 0.1 0.3 0.8 0.1 4.4 0.1 1.0 1.1 0.3 0.2 0.3 0.2 0.3 1.9 0.2 0.8 0.1 0.3 0.0 0.2 5.8 0.1 0.1 0.0 0.1 1.5 0.1 0.2 59.8 0.1 0.1 0.3 0.1 0.5 0.3 0.1 0.4 0.1 24.7 1.7 0.6 1.1 0.0 0.5 0.5 0.2 0.0 4.2 5.6 4.4 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 39.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.0 1.2 0.1 0.0 4.7 0.7 0.3 0.0 0.2 0.5 0.0 0.0 0.3 0.1 6.0 1.4 0.8 1.0 1.0 1.4 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 1.8 0.2 4.2 0.0 1.6 1.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.5 1.9 5.6 0.3 0.2 0.2 1.3 0.3 0.2 0.2 0.8 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.4 0.9 0.0 0.0 0.0 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785460-2815807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Enterocytes: 167.6;Paneth cells: 149.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol NA NA 1400000 Cytosol "CAB025497: , HPA035262: AB_2674541" "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 8.2 9.4 19.1 12.3 19.8 18.4 6.2 21.7 26.1 5.2 11.8 14.1 5.8 24.6 7.5 8.4 11.0 8.4 6.7 11.6 18.5 15.4 7.1 30.4 6.2 11.9 14.1 15.2 11.1 7.8 7.0 12.7 22.3 13.1 18.1 8.2 11.9 13.7 6.8 29.1 11.9 20.0 7.1 10.7 9.8 7.8 27.3 10.9 17.0 7.5 11.5 11.3 5.8 6.8 7.5 9.8 8.0 7.5 3.9 9.5 3.2 29.4 21.9 8.6 18.3 4.4 4.3 30.5 18.4 6.8 18.3 14.8 25.7 9.4 26.6 9.0 7.1 12.8 24.0 12.7 15.1 7.7 0.1 26.6 9.4 24.1 30.4 4.7 18.1 14.7 4.8 5.4 15.2 6.8 5.2 10.4 18.0 21.8 13.0 7.7 22.8 20.1 34.0 25.2 8.8 30.2 16.7 11.4 25.1 7.6 17.1 23.3 18.5 16.1 14.5 8.9 4.6 14.0 17.6 11.7 14.1 12.1 30.0 31.1 22.8 19.1 17.9 15.7 30.4 16.7 8.0 3.5 1.6 5.5 3.9 4.5 5.6 4.0 7.4 4.9 7.5 5.1 4.3 1.7 3.9 7.5 9.8 9.5 3.2 19.1 19.8 21.7 26.1 18.5 15.4 14.1 15.2 13.1 10.9 3.0 11.7 12.3 8.7 6.1 20.3 7.3 10.2 5.3 7.9 10.4 33.4 20.9 8.3 17.0 11.4 5.7 167.6 0.0 12.9 46.8 8.4 12.6 5.7 79.1 19.9 6.4 39.2 6.2 9.5 18.4 10.6 7.0 3.3 11.8 46.9 12.9 15.9 149.7 5.6 9.1 29.7 12.9 9.2 47.9 19.4 5.1 28.3 6.5 38.5 6.4 THTPA THTPASE ENSG00000259431 "Thiamine triphosphatase" Q9BU02 14 23555988-23560271 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Distal tubular cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028876 Approved Uncertain Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA028876: AB_10600731" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (7.11e-2)" "unprognostic (2.25e-1)" "unprognostic (2.12e-1)" "unprognostic (4.13e-1)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.70e-9)" "unprognostic (3.47e-2)" "unprognostic (2.32e-1)" "unprognostic (3.62e-2)" "unprognostic (5.40e-2)" 14.9 19.5 27.7 12.2 23.3 7.6 12.9 16.4 24.3 12.3 14.0 20.7 15.9 15.7 13.3 18.4 10.1 17.7 16.8 16.3 23.3 17.4 16.3 12.1 10.7 10.7 21.9 13.3 15.4 12.7 25.0 12.4 7.6 16.1 18.8 12.3 17.1 18.0 23.5 21.9 7.4 11.7 13.7 19.5 11.3 11.6 18.8 14.3 14.1 15.9 12.3 11.2 9.9 7.9 14.3 17.0 11.1 14.4 6.9 11.6 8.7 2.7 17.1 8.4 9.1 19.3 10.9 4.6 8.0 7.1 7.9 7.9 3.5 11.3 5.2 7.0 9.6 9.0 8.5 8.8 10.0 5.9 10.9 9.6 7.0 12.1 9.3 9.8 6.4 6.4 14.8 7.4 12.1 8.9 16.7 9.5 8.4 5.3 11.4 11.5 8.2 10.1 2.6 3.0 14.6 14.6 6.9 5.7 9.4 13.9 5.4 16.2 7.7 7.9 16.2 4.6 5.2 10.8 3.1 7.4 5.2 5.5 10.7 4.7 13.5 8.2 2.9 5.4 2.9 8.0 11.1 14.4 7.3 9.6 10.6 9.5 9.6 6.9 7.5 13.2 14.3 11.6 9.9 1.5 6.9 13.4 17.0 5.4 8.7 27.7 23.3 16.4 24.3 23.3 17.4 21.9 13.3 16.1 14.3 6.0 6.9 15.9 5.8 0.0 27.6 0.0 10.2 5.3 6.8 7.0 7.9 9.0 46.4 13.0 16.7 2.9 8.4 0.0 10.7 4.4 7.2 8.5 23.1 7.6 15.9 7.9 5.8 8.0 10.0 16.8 10.6 8.2 0.0 11.8 6.4 18.8 8.1 8.6 7.1 24.6 9.4 12.9 0.1 19.6 8.7 0.0 5.6 6.4 8.5 5.4 TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4354593 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hofbauer cells: 53.0;monocytes: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 36.9;SuSa: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol NA NA Cytosol "CAB034010: AB_1128227, HPA040354: AB_2676935, HPA044111: AB_2678814" "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" 14.3 14.3 8.3 12.3 10.8 10.5 7.1 3.7 17.8 6.3 10.4 10.1 6.4 6.7 7.5 7.3 10.3 5.7 8.5 9.8 9.5 7.9 7.7 11.0 10.4 12.3 13.5 7.9 6.0 5.2 9.0 14.4 14.6 12.2 7.5 13.5 8.4 8.2 9.5 13.6 6.2 8.7 12.5 12.3 14.9 8.5 8.4 8.3 8.9 6.0 6.6 12.6 13.9 8.9 3.7 14.0 4.7 15.5 3.2 5.7 3.6 5.3 8.6 7.0 8.1 6.6 6.4 36.9 9.3 7.9 7.1 9.7 10.4 5.5 6.0 1.3 6.4 7.6 6.8 7.4 15.9 8.9 7.7 5.4 0.1 5.7 8.5 14.0 3.3 1.2 11.6 19.2 8.3 15.0 4.4 14.4 4.4 0.6 4.5 14.3 7.9 2.9 1.7 15.0 6.3 2.6 4.2 11.4 2.2 6.9 10.9 0.2 4.2 8.8 4.4 11.5 36.2 1.4 2.9 12.4 9.6 12.4 7.5 5.2 3.8 3.8 10.3 6.7 2.3 7.6 0.5 8.2 0.7 3.6 14.4 3.4 3.7 2.8 3.9 14.0 2.9 1.9 3.2 4.7 3.2 15.5 5.5 5.7 3.6 8.3 10.8 3.7 17.8 9.5 7.9 13.5 7.9 12.2 8.3 0.0 1.7 11.5 7.6 0.0 3.3 9.7 2.5 0.0 0.0 5.2 17.7 23.6 13.3 13.4 23.6 8.7 1.6 0.0 12.0 23.6 8.6 7.1 0.0 5.1 53.0 1.6 7.0 5.5 19.7 22.4 3.4 12.3 0.0 43.3 1.8 11.0 13.1 3.5 4.2 7.3 3.1 6.5 6.6 17.0 23.4 0.0 28.7 4.4 2.0 10.8 TMEM2 ENSG00000135048 "Transmembrane protein 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 67.6" "Cell type enhanced" "Detected in many" 5 "Ito cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.6;BEWO: 34.0;OE19: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044889 Approved Supported "Vesicles,Plasma membrane" NA NA 130000 "Plasma membrane" Vesicles "HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" 23.3 3.9 6.0 10.5 4.4 12.4 13.6 8.9 6.0 3.0 18.6 1.9 10.1 12.2 4.5 5.2 4.4 4.9 19.2 9.5 8.6 3.6 9.3 24.9 35.7 14.0 4.0 4.1 3.1 9.2 24.0 9.5 67.6 4.3 5.5 13.1 7.9 9.5 10.2 5.5 6.4 20.0 5.5 5.1 15.6 14.5 3.7 2.4 6.4 8.0 4.6 8.8 11.4 6.8 6.3 0.9 5.5 2.1 0.5 4.1 1.4 5.8 28.0 36.6 1.7 3.8 6.9 34.0 19.7 12.6 13.7 10.1 7.8 8.0 0.1 5.9 5.0 3.0 8.7 11.8 2.7 18.6 0.7 3.6 10.0 5.9 20.8 5.9 0.0 2.7 7.1 3.0 10.6 2.4 3.6 18.0 0.8 1.4 3.0 7.4 4.9 1.1 0.1 7.6 36.1 2.7 0.9 10.9 0.7 8.6 18.9 1.8 0.2 5.1 3.6 5.3 11.8 2.5 0.3 7.8 9.3 10.5 5.1 9.8 0.6 8.4 0.3 1.8 0.9 11.7 0.2 2.1 5.5 2.7 1.9 0.8 0.7 2.9 2.6 0.9 6.3 4.1 2.0 4.5 0.5 1.8 0.2 3.9 1.4 6.0 4.4 8.9 6.0 8.6 3.6 4.0 4.1 4.3 2.4 32.8 30.4 9.4 38.3 26.8 5.5 0.0 33.1 4.0 17.0 0.0 9.8 36.3 0.0 0.0 10.6 37.9 75.4 0.0 0.0 12.0 19.0 42.5 4.6 27.6 35.9 0.0 9.7 115.4 56.5 2.9 2.8 14.9 16.9 0.0 32.3 73.6 0.0 26.4 1.1 0.0 35.2 6.5 20.8 1.0 0.6 19.2 75.1 62.3 28.3 40.3 TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226639-55229264 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 15.1" "Cell type enhanced" "Detected in many" 10 "Cholangiocytes: 30.6;Hepatocytes: 28.9" "Cancer enriched" "Detected in all" 5 "liver cancer: 10.0" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA057689 Uncertain Uncertain Midbody,Centrosome Yes No Centrosome Midbody "HPA057689: AB_2683504" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.76e-5)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "prognostic favorable (3.13e-4)" "unprognostic (1.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "prognostic favorable (9.97e-6)" "unprognostic (1.96e-2)" "unprognostic (6.63e-8)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (3.70e-1)" "unprognostic (3.19e-3)" 2.5 2.4 2.8 3.1 4.0 7.8 1.4 4.7 4.2 1.4 7.5 1.4 1.4 5.6 1.5 1.4 1.4 1.8 7.7 2.9 2.2 1.6 2.0 15.1 2.7 5.2 1.4 1.4 1.4 1.4 1.7 2.8 5.2 1.7 1.5 0.4 1.4 1.4 1.4 2.2 3.0 7.7 1.4 1.4 4.3 3.6 2.8 1.4 1.4 2.3 1.4 3.0 1.4 1.4 0.7 1.0 0.6 0.7 0.0 1.6 0.4 4.1 3.9 2.4 3.9 0.4 0.6 3.6 1.5 0.7 1.3 1.8 6.3 2.2 4.8 1.2 1.1 1.3 1.7 0.9 1.0 0.6 0.9 11.2 8.8 2.5 5.9 1.2 4.0 3.7 0.8 1.7 2.1 1.3 1.8 0.5 9.2 6.0 3.5 0.8 2.4 6.4 10.0 0.9 1.9 2.4 6.0 2.8 12.6 1.1 5.1 2.1 3.9 1.8 0.8 4.9 1.3 2.2 8.4 2.8 5.7 3.2 2.5 3.8 2.9 3.4 10.2 4.7 11.1 2.1 0.0 0.7 0.6 1.6 0.1 0.6 0.0 0.5 0.1 0.1 0.7 0.6 1.4 0.1 0.0 0.1 1.0 0.0 0.4 2.8 4.0 4.7 4.2 2.2 1.6 1.4 1.4 1.7 1.4 6.0 2.4 0.8 0.4 3.0 7.6 0.5 30.6 0.0 1.2 0.0 2.0 0.4 0.0 0.9 2.0 1.7 5.2 0.0 0.2 0.3 1.1 1.1 0.0 28.9 0.9 9.5 10.3 0.0 6.2 3.6 0.9 1.7 3.3 1.8 1.9 1.1 0.8 0.0 0.4 0.8 3.6 0.0 0.5 1.6 1.1 1.9 0.2 4.6 1.9 1.7 TMEM8A "M83, PGAP6, TMEM6, TMEM8" ENSG00000129925 "Transmembrane protein 8A" Q9HCN3 16 370773-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Enterocytes: 67.7;Syncytiotrophoblasts: 83.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 24.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No Nucleoplasm "Cytokinetic bridge" "HPA051281: AB_2681418, HPA064673: AB_2685317" "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" 8.4 9.3 6.9 9.5 7.8 15.2 13.5 7.7 7.9 6.8 16.6 7.3 24.1 17.7 7.3 29.6 11.8 6.5 15.2 10.0 5.6 4.3 28.7 33.5 13.0 10.7 7.1 3.2 8.3 44.2 11.5 10.7 45.5 6.7 11.4 6.0 8.8 22.5 8.8 12.8 3.7 25.0 5.0 4.7 13.2 17.5 26.3 6.0 12.6 12.3 5.2 14.6 9.3 8.8 2.0 2.9 24.3 5.5 0.9 7.6 3.3 4.4 11.8 6.8 12.5 9.3 8.4 13.6 12.9 13.5 6.6 9.5 46.4 21.1 4.8 17.5 12.4 10.1 6.4 3.0 14.2 1.8 13.6 11.3 7.9 8.0 26.4 21.6 5.9 15.0 9.7 4.3 10.1 2.9 6.7 15.2 5.4 12.6 7.4 8.2 27.8 8.3 11.7 10.8 7.2 4.7 18.1 7.8 10.9 10.7 11.5 8.1 9.3 7.2 7.3 37.9 3.7 13.1 11.9 22.1 18.8 20.3 13.0 6.8 14.9 7.4 9.5 9.5 6.3 11.9 4.6 5.0 6.3 7.4 5.5 5.9 1.8 5.8 5.8 2.5 2.0 7.6 5.5 24.3 0.9 3.8 2.9 4.3 3.3 6.9 7.8 7.7 7.9 5.6 4.3 7.1 3.2 6.7 6.0 14.9 12.5 10.7 3.2 2.6 5.7 12.5 10.2 1.4 1.2 22.7 9.8 46.7 5.0 27.5 15.5 8.7 67.7 23.3 36.8 5.9 6.6 11.5 1.1 25.5 24.7 17.5 26.6 14.7 14.5 58.4 2.6 10.1 6.8 8.2 26.1 8.2 42.6 38.6 1.8 9.9 7.8 12.9 6.1 1.1 2.5 2.8 83.8 7.5 18.9 6.8 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 67 "intestine: 154.6" "Cell type enriched" "Detected in single" 11 "Early spermatids: 4.2" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 20 "U-138 MG: 20.3;U-87 MG: 56.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "olfactory region: 9.3" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Nucleoli,Plasma membrane" NA NA "Plasma membrane" Nucleoli "HPA015611: AB_1855791, HPA034857: , HPA072934: AB_2732214" "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 80.5 0.0 0.0 154.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 42.4 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.5 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 0.1 0.0 0.3 0.0 0.1 56.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867188-137883312 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.4" "Cell type enhanced" "Detected in many" 10 "Basal keratinocytes: 688.4;Suprabasal keratinocytes: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 31.8;Karpas-707: 48.1;REH: 41.8;U-266/84: 35.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 27.4 6.0 1.5 58.6 1.8 112.4 17.2 0.4 1.5 7.7 15.7 3.2 2.6 5.1 9.7 7.3 12.7 12.1 17.0 11.7 2.1 1.3 6.8 8.1 45.1 38.8 2.1 2.6 37.5 7.2 2.1 3.7 14.5 4.6 13.8 6.3 7.2 8.2 3.5 10.7 20.5 17.2 8.2 3.8 25.9 8.0 9.3 2.1 38.6 5.7 9.2 31.4 23.3 9.5 7.1 18.6 10.0 9.7 7.5 20.5 9.0 8.9 1.4 0.5 0.8 3.0 5.1 2.1 5.1 19.9 1.4 1.8 9.9 2.9 2.0 13.1 5.8 31.8 6.8 0.3 14.7 2.6 14.5 0.5 2.0 5.1 5.8 3.3 2.7 3.6 4.6 2.1 16.8 16.0 1.7 0.8 5.3 4.0 48.1 2.4 0.5 14.7 11.5 0.3 0.6 0.4 41.8 10.4 1.4 4.3 4.3 0.2 0.0 1.0 1.5 4.3 2.1 1.0 3.3 4.0 14.4 1.7 12.9 2.9 15.5 35.9 4.1 5.2 3.4 1.7 5.6 9.7 5.5 14.8 7.1 20.5 6.2 15.1 13.3 10.3 7.1 10.0 7.4 10.0 7.5 3.7 18.6 14.7 9.0 1.5 1.8 0.4 1.5 2.1 1.3 2.1 2.6 4.6 2.1 35.7 83.1 25.1 141.6 688.4 1.0 4.2 30.6 41.5 26.1 0.0 27.5 5.5 1.7 50.3 2.3 27.0 39.0 0.0 23.4 88.6 55.5 117.9 248.4 10.2 45.4 0.0 11.3 45.4 74.2 2.4 6.4 241.1 123.2 82.0 12.5 1.7 27.9 8.2 5.6 2.2 13.3 6.5 87.3 0.9 2.3 651.8 19.3 101.2 8.5 60.3 TPP1 "CLN2, SCAR7" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612763-6619485 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Hofbauer cells: 223.6;Kupffer cells: 312.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 13000000 "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 37.4 64.6 32.2 28.8 36.2 43.0 23.1 15.1 33.3 24.0 26.8 41.7 13.2 28.0 32.0 22.3 20.3 18.0 26.9 25.6 24.5 25.1 36.0 45.1 35.9 42.3 31.0 29.3 22.0 14.8 35.1 30.0 56.4 25.4 19.4 28.2 43.4 18.4 29.1 15.4 15.5 31.4 42.4 32.8 69.0 19.8 17.9 24.7 21.7 24.0 9.1 26.9 25.6 29.4 9.4 43.5 12.8 38.9 7.0 15.3 26.2 4.8 9.8 4.9 9.3 57.7 31.9 3.8 9.5 45.1 7.4 12.9 4.0 20.7 6.9 6.3 24.0 45.7 14.5 9.7 13.3 11.2 6.9 5.6 5.6 5.1 10.9 43.6 8.1 34.2 47.8 21.7 8.6 19.2 49.8 31.5 6.5 10.7 21.0 21.6 6.0 2.5 10.0 3.5 11.4 11.8 6.3 4.1 13.6 13.1 7.6 0.6 3.8 10.2 7.6 17.8 16.9 5.0 15.5 36.0 21.4 6.1 19.2 3.4 17.8 17.4 2.4 27.1 19.0 11.2 12.8 37.7 8.9 10.7 38.9 8.7 9.4 8.5 11.0 43.5 8.5 5.8 7.6 6.9 7.0 26.4 24.2 15.3 26.2 32.2 36.2 15.1 33.3 24.5 25.1 31.0 29.3 25.4 24.7 23.8 31.2 61.7 25.6 21.1 22.8 35.0 58.6 10.7 23.9 15.7 11.8 31.4 5.0 32.3 10.2 39.0 51.3 23.3 11.7 36.7 29.8 25.6 62.2 63.8 223.6 14.3 16.0 90.9 312.0 7.8 25.0 115.7 86.0 64.1 29.1 42.4 18.5 39.0 24.8 46.1 22.8 6.5 22.7 0.5 1.1 17.6 73.6 44.8 28.0 23.0 TPP2 TPPII ENSG00000134900 "Tripeptidyl peptidase 2" P29144 13 102597003-102679958 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 9 "Early spermatids: 628.9;Late spermatids: 647.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021069, HPA049630" Approved Supported "Nuclear bodies,Cytosol" NA NA 410000 "Nuclear bodies, Cytosol" "HPA021069: AB_1858344, HPA049630: AB_2680836" "unprognostic (4.75e-2)" "unprognostic (4.78e-2)" "unprognostic (9.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-2)" "unprognostic (4.43e-2)" "unprognostic (2.45e-2)" "unprognostic (8.33e-3)" "unprognostic (5.02e-2)" "unprognostic (1.51e-1)" "unprognostic (3.12e-1)" "unprognostic (2.75e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.95e-2)" "unprognostic (3.43e-3)" 19.9 12.4 10.8 21.4 14.5 24.7 18.1 23.1 18.4 16.8 14.7 12.2 50.3 13.1 20.0 21.8 14.4 16.7 13.5 17.0 11.7 9.7 12.9 22.8 18.4 32.8 11.7 13.8 21.6 16.3 15.7 15.7 19.2 15.3 13.9 21.0 12.9 15.6 34.5 35.7 14.1 17.4 19.2 13.4 20.7 15.4 34.5 14.0 23.8 21.9 16.0 19.7 17.0 16.0 6.0 5.8 9.2 6.9 10.9 12.1 4.7 16.2 6.5 18.9 16.1 12.8 17.7 13.5 16.6 12.2 10.7 13.4 13.8 21.9 17.9 5.7 13.4 12.1 16.0 14.6 11.7 19.4 12.4 13.0 34.0 17.1 11.0 10.8 38.4 20.7 13.7 5.3 12.0 16.1 11.5 15.3 17.5 20.2 20.0 15.1 5.1 17.6 28.8 15.3 21.0 9.1 19.6 14.3 16.1 13.9 13.4 17.6 14.4 10.4 17.4 7.4 15.4 10.0 43.1 12.2 10.2 7.4 6.5 13.8 19.7 23.8 15.6 17.0 27.7 13.1 9.2 6.0 4.0 9.1 6.9 10.7 6.0 10.3 10.1 5.8 5.5 12.1 11.5 1.3 10.9 5.7 4.6 10.9 4.7 10.8 14.5 23.1 18.4 11.7 9.7 11.7 13.8 15.3 14.0 35.7 35.3 24.4 13.2 13.7 25.9 36.2 7.6 50.9 23.9 14.0 68.7 24.1 8.3 16.1 628.9 16.1 9.5 23.3 7.5 23.0 16.0 13.4 37.0 19.2 27.1 7.9 19.0 25.2 21.0 647.3 29.7 22.2 16.9 16.2 16.9 12.9 12.1 15.3 17.7 11.2 44.7 25.8 17.5 51.0 29.6 11.7 27.7 27.7 18.3 16.5 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240696-1242554 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 24 "granulocytes: 5492.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 308 "basophil: 30.8" "Lineage enriched" "Detected in single" 308 "granulocytes: 30.8" "Cell line enriched" "Detected in some" 173 "HMC-1: 301.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 22.4 0.2 1.6 5.8 1.6 0.0 10.6 1.6 1.6 13.9 17.1 1.6 1.6 17.7 18.7 10.4 15.2 6.1 33.1 4.7 1.6 0.0 4.4 2.8 29.2 16.8 1.6 1.6 2.9 4.5 0.0 1.6 1.9 1.6 24.1 10.0 5.1 14.6 6.3 3.6 29.9 31.0 15.0 1.6 1.6 24.5 5.1 1.6 3.1 3.7 3.8 6.9 21.6 16.0 0.0 0.0 30.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 301.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.6 1.6 1.6 1.6 0.0 1.6 1.6 1.6 1.6 23.8 231.9 0.0 1.4 16.6 0.0 0.2 0.0 9.4 14.8 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 17.1 2.5 5492.7 0.0 5.5 0.0 0.0 0.0 0.3 0.0 0.0 9.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.1 8.7 0.2 1.0 0.0 5.6 TPSB2 ENSG00000197253 "Tryptase beta 2 (gene/pseudogene)" P20231 16 1227272-1230184 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.2" "Cell type enriched" "Detected in some" 18 "granulocytes: 8345.3" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 84 "basophil: 8.4" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.4" "Cell line enriched" "Detected in some" 8 "HMC-1: 83.3" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 7500000 "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 1.8 0.0 0.9 1.9 0.9 0.0 4.1 0.9 0.9 8.8 5.3 0.9 0.9 4.9 2.9 0.9 7.7 0.1 16.2 0.9 0.9 0.9 0.9 12.3 2.4 0.9 0.9 0.9 1.3 0.0 0.9 0.9 0.9 2.7 2.3 0.9 6.2 1.2 0.9 3.4 9.7 4.4 0.9 0.9 13.6 0.9 0.9 0.9 0.9 0.9 0.9 4.2 0.9 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.1 83.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.7 468.0 0.0 1.9 0.0 0.0 1.3 0.0 6.7 30.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.9 8345.3 0.0 4.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 4.6 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1258998 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 17 "granulocytes: 189.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "basophil: 6.4" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.4" "Group enriched" "Detected in some" 48 "HEL: 18.7;HMC-1: 28.6" "CAB002215, CAB032871, HPA040182, HPA049554" Supported "Intracellular and membrane" NA NA "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: AB_2676875, HPA049554: AB_2680815" "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 6.6 0.1 0.6 3.8 0.6 0.8 3.7 0.6 0.8 3.2 5.6 0.6 0.6 2.7 7.5 3.3 7.6 2.3 13.0 2.0 0.6 0.0 1.3 2.3 17.0 13.7 0.6 0.6 0.6 0.9 0.1 0.6 0.9 0.6 4.3 0.4 3.1 3.6 0.7 1.6 7.8 9.3 4.7 0.6 0.6 15.7 3.5 0.6 1.6 1.1 2.8 2.6 8.9 6.6 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.1 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.8 0.6 0.0 0.6 0.6 0.6 0.6 3.0 11.4 0.0 0.0 0.3 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 189.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 69 "testis: 78.6" "Group enriched" "Detected in some" 14 "Spermatocytes: 282.4;Spermatogonia: 73.0" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.4;K-562: 8.6;Karpas-707: 7.0;MCF7: 5.1;PC-3: 5.2;RPMI-8226: 9.5;SuSa: 8.9;U-2 OS: 4.6;U-266/70: 8.5" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA Cytosol "Endoplasmic reticulum" "HPA049690: AB_2680850, HPA068342: AB_2685976" "unprognostic (3.63e-2)" 0.1 0.0 0.0 0.7 0.2 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.8 0.4 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.4 0.0 0.9 0.0 78.6 0.0 0.4 0.1 0.4 0.8 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 7.0 0.0 5.1 0.0 0.0 1.2 0.0 5.2 0.0 0.0 9.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 8.9 0.0 0.0 0.0 2.0 4.6 2.4 0.0 8.5 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.6 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 12.9 0.0 282.4 73.0 0.0 0.9 0.0 0.0 0.0 TPTE2 TPIP ENSG00000132958 "Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2" Q6XPS3 13 19422877-19536762 "Enzymes, Plasma proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 12.3" "Cell type enhanced" "Detected in some" 23 "Collecting duct cells: 1.8;Early spermatids: 3.5;Spermatocytes: 9.3;Spermatogonia: 2.5" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 10.1;Karpas-707: 2.9" HPA068342 Approved "Endoplasmic reticulum,Cytosol" NA NA Cytosol "Endoplasmic reticulum" "HPA068342: AB_2685976" "unprognostic (2.50e-1)" "unprognostic (2.10e-1)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (5.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (5.40e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-1)" "unprognostic (1.05e-12)" "unprognostic (1.04e-1)" "unprognostic (1.47e-1)" "unprognostic (2.44e-1)" "unprognostic (5.00e-3)" 0.0 0.1 0.4 0.2 1.0 0.0 0.1 0.7 0.8 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.2 12.3 0.0 0.6 0.0 0.0 0.5 0.4 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 10.1 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 2.9 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 1.4 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.3 9.3 2.5 0.1 0.1 0.0 0.0 0.0 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 51.8" "Cell type enriched" "Detected in some" 6 "Late spermatids: 233.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;Hep G2: 2.1;RPMI-8226: 1.9;SiHa: 1.8;SK-MEL-30: 1.5;U-2 OS: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039913, HPA042045" Enhanced "Intracellular and membrane" NA NA 12000000 "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.1 24.1 0.0 0.0 28.9 0.1 3.3 0.6 0.1 3.7 0.1 0.1 0.1 6.1 2.6 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.1 0.1 51.8 0.0 0.1 0.1 0.6 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 5.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.2 0.9 1.8 0.3 1.5 0.1 0.7 0.0 0.8 0.1 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.6 0.1 37.2 0.0 2.9 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 2.9 0.0 0.0 233.7 2.0 0.0 0.0 0.0 0.9 0.0 0.6 5.8 1.8 16.5 0.0 0.0 0.1 1.8 0.8 0.0 0.0 0.0 1.2 0.0 TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease mutation, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 20 "Basal keratinocytes: 8.0;Cardiomyocytes: 5.0;Melanocytes: 23.6;Smooth muscle cells: 7.6;Suprabasal keratinocytes: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 30.9" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol NA NA Cytosol "HPA035437: AB_10672092, HPA046721: AB_2732531" 14.2 14.3 16.7 14.6 10.6 20.7 17.2 13.0 16.9 13.4 11.0 12.8 17.5 10.3 8.1 14.9 16.6 14.5 12.3 9.8 14.4 14.2 11.6 12.7 12.5 26.2 14.6 17.4 7.3 13.0 6.8 31.2 11.6 11.2 15.4 9.3 10.8 32.2 19.3 10.8 22.9 10.9 8.2 12.6 25.5 12.4 4.6 10.1 18.5 7.4 18.3 21.7 13.3 10.6 24.9 35.5 23.3 41.8 8.6 13.1 20.1 8.0 7.4 6.2 4.4 7.7 7.9 0.0 2.6 13.1 22.0 30.9 0.1 9.6 9.5 5.4 11.1 20.8 9.4 0.4 11.8 3.1 8.0 0.7 5.5 26.5 0.4 9.7 5.0 3.9 6.9 1.1 11.1 4.4 4.5 9.3 6.6 0.0 14.6 9.3 0.1 7.0 3.6 0.0 4.7 4.6 5.8 1.6 18.5 5.8 1.6 0.0 3.7 9.6 13.0 6.3 0.4 0.4 8.4 9.8 4.1 3.9 8.7 6.1 11.8 6.8 4.0 9.1 10.7 3.3 2.1 41.8 3.0 9.8 32.5 5.6 24.6 13.1 9.4 35.5 24.9 12.4 10.3 23.3 8.6 24.3 28.0 11.6 20.1 16.7 10.6 13.0 16.9 14.4 14.2 14.6 17.4 11.2 10.1 0.0 0.3 0.0 0.0 8.0 0.0 5.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 12.2 0.0 0.0 0.0 0.0 TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 39.6" "Cell type enhanced" "Detected in single" 21 "Suprabasal keratinocytes: 1.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.9;eosinophil: 5.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 5.7" "Cell line enhanced" "Detected in many" "HEK 293: 7.6;U-698: 10.3;U-937: 9.6" "Not detected" "Not detected" HPA054060 Uncertain NA NA "HPA054060: AB_2682362" "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" 3.2 1.5 2.1 3.4 3.0 1.9 2.1 1.1 3.6 4.3 2.6 1.9 15.5 1.4 2.5 2.2 4.5 2.6 2.2 3.5 1.6 1.2 2.8 4.6 2.4 3.1 2.4 2.4 2.1 2.2 1.5 1.7 2.6 2.7 2.5 1.4 1.4 4.5 7.4 2.0 39.6 2.3 1.9 1.2 4.3 1.7 2.1 1.9 5.8 3.3 6.2 4.7 2.2 5.2 0.4 0.3 5.7 0.1 0.2 0.4 0.2 2.8 3.6 0.3 1.3 0.5 0.7 0.3 0.9 0.8 0.7 2.0 1.0 0.7 0.3 1.9 0.8 0.2 3.1 1.2 2.0 0.0 3.2 7.6 0.3 0.7 0.4 0.3 0.8 2.0 0.8 1.9 0.9 0.7 0.4 0.3 0.6 0.4 3.5 0.2 3.3 2.0 2.3 1.2 0.6 2.4 4.9 1.0 2.3 0.3 1.0 0.8 0.4 0.3 0.3 1.1 0.1 0.6 0.9 0.0 1.3 2.4 2.8 1.1 4.0 2.7 10.3 0.3 9.6 1.5 3.9 0.0 5.7 0.3 0.0 0.2 0.4 0.1 0.3 0.3 0.3 0.4 0.1 0.0 0.2 0.1 0.0 0.1 0.2 2.1 3.0 1.1 3.6 1.6 1.2 2.4 2.4 2.7 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.6 0.0 0.0 0.0 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670757 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.3;pancreas: 19.4" "Group enriched" "Detected in some" 4 "Early spermatids: 30.7;Late spermatids: 47.8;Leydig cells: 27.3;Peritubular cells: 12.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Region enhanced" "Detected in many" "cerebellum: 30.3" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BJ: 20.8;BJ hTERT+: 20.2;EFO-21: 10.9;HBF TERT88: 7.4;hTERT-RPE1: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 6200000 "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 6.2 2.2 2.9 1.0 4.7 1.0 7.6 30.3 12.3 10.2 2.4 0.1 2.5 4.8 2.7 1.7 0.9 2.5 2.5 2.2 7.3 2.8 9.9 1.5 3.0 0.6 1.2 5.5 6.5 19.4 0.4 1.6 0.7 1.5 5.5 1.5 1.0 2.4 5.8 0.7 0.8 4.2 1.2 0.9 4.8 1.1 1.7 0.5 0.0 0.5 0.4 1.0 2.8 7.6 0.2 0.0 1.0 0.3 0.3 0.0 0.0 2.4 0.0 0.4 0.0 1.1 0.0 6.7 20.8 20.2 2.0 1.4 0.0 0.0 0.0 10.9 3.0 2.1 0.2 3.8 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.0 0.0 0.0 0.0 6.9 4.6 2.0 0.0 0.0 0.0 0.0 0.4 0.0 4.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 2.9 4.7 30.3 12.3 7.3 2.8 1.2 5.5 1.5 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.0 1.4 0.0 1.8 0.0 0.0 3.3 0.0 30.7 0.0 6.9 0.0 2.2 0.3 0.5 0.2 0.0 1.3 0.2 0.0 0.0 0.0 0.0 47.8 27.3 0.3 0.0 0.0 1.5 0.3 2.1 2.9 12.7 7.4 0.6 0.0 0.4 0.1 0.7 0.0 0.1 0.0 0.7 0.1 TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994401 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease mutation, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 8 "Club cells: 5.7;Cytotrophoblasts: 3.6;Distal tubular cells: 3.3;Ductal cells: 3.9;Pancreatic endocrine cells: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain NA NA "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" 8.5 12.1 8.4 11.1 9.9 4.2 12.6 8.7 10.4 6.1 7.3 6.0 2.6 5.4 9.1 9.0 10.1 11.4 6.6 8.4 8.7 5.1 8.4 10.8 4.4 9.6 10.6 7.4 9.8 14.7 9.5 11.1 6.4 9.4 7.7 8.3 3.9 6.8 5.9 32.5 9.6 6.8 7.4 12.2 10.4 7.0 15.0 10.9 12.6 8.9 9.8 13.1 6.6 14.1 5.4 2.4 1.1 1.5 4.7 7.8 2.5 6.5 13.8 5.5 17.5 5.1 3.5 6.6 4.8 6.5 7.8 7.8 22.8 5.8 23.7 9.4 2.9 4.7 11.0 23.1 12.0 9.9 11.0 13.6 17.9 8.1 17.5 8.5 22.9 7.4 6.8 13.8 11.3 35.8 7.2 4.7 11.7 19.2 6.6 5.4 8.9 15.5 8.4 15.9 12.4 11.6 15.2 12.2 14.5 5.1 6.7 9.0 17.3 5.2 7.1 17.3 6.5 9.3 7.8 5.4 3.9 7.9 4.8 14.1 12.4 12.8 20.3 4.7 21.0 4.3 1.1 1.1 0.1 2.6 0.9 7.8 5.4 3.8 5.0 2.1 4.0 4.1 4.5 0.0 4.7 1.5 2.4 1.0 2.5 8.4 9.9 8.7 10.4 8.7 5.1 10.6 7.4 9.4 10.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 1.8 0.0 3.6 3.3 3.9 0.0 0.0 0.0 0.0 2.5 2.8 0.0 0.0 1.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.8 0.0 0.0 3.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655675-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.5;lymphoid tissue: 27.7" "Cell type enhanced" "Detected in many" 7 "Cytotrophoblasts: 29.2;Extravillous trophoblasts: 45.7;Hofbauer cells: 34.3;Kupffer cells: 31.7;Syncytiotrophoblasts: 39.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 32.5;pons and medulla: 21.2" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 42.6;HMC-1: 32.5;hTEC/SVTERT24-B: 26.5;REH: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038607" Approved Approved "Plasma membrane" NA NA 2200000 "Plasma membrane" "HPA038605: AB_10669648, HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 4.3 1.3 2.8 5.5 4.0 7.2 1.5 32.5 4.9 4.0 1.5 0.7 0.0 1.7 1.3 0.3 1.8 1.1 2.4 1.3 3.4 3.5 1.5 1.7 5.5 10.9 5.1 1.9 0.8 1.2 0.6 0.9 16.8 21.2 1.3 1.8 0.9 1.3 0.9 1.8 4.1 2.4 2.3 2.1 27.7 1.7 2.1 0.2 23.9 2.9 1.7 3.8 3.4 1.3 1.0 1.7 9.8 11.0 6.5 4.9 1.8 4.5 11.1 2.0 2.7 0.9 1.6 10.6 16.2 9.0 6.6 5.1 4.4 2.4 1.8 1.3 8.6 6.3 2.2 0.0 5.8 10.5 0.0 0.3 42.6 0.3 3.7 2.5 5.1 32.5 1.4 0.3 26.5 9.8 7.2 4.4 1.9 0.0 0.0 6.4 0.1 6.3 3.3 0.9 4.6 2.6 25.4 1.2 0.2 10.4 3.8 4.6 0.1 4.3 0.3 3.6 4.4 0.0 1.4 11.4 8.6 4.6 5.0 6.7 0.4 0.0 5.4 4.5 7.3 15.5 0.0 1.3 9.8 2.0 6.5 2.2 0.3 2.6 1.8 1.7 1.0 3.0 1.6 2.8 6.5 11.0 0.2 4.9 1.8 2.8 4.0 32.5 4.9 3.4 3.5 5.1 1.9 21.2 0.2 0.0 6.6 0.0 3.5 6.4 0.6 1.2 0.0 0.0 1.2 3.5 0.0 29.2 0.0 9.2 1.9 4.2 0.4 0.0 8.3 45.7 4.2 2.9 12.7 0.0 34.3 11.1 0.0 4.9 31.7 2.8 0.0 19.6 1.7 0.0 0.0 0.5 16.9 0.0 0.4 0.0 1.1 0.0 4.2 0.0 0.5 5.3 39.8 7.2 0.3 2.7 UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263081-159286040 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA039615: AB_10674425" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "unprognostic (6.04e-3)" "unprognostic (3.45e-2)" "unprognostic (7.08e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (4.46e-5)" "unprognostic (4.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (2.51e-2)" 17.1 16.0 16.7 18.4 19.7 16.7 16.3 20.2 33.0 18.5 12.5 12.2 11.4 9.8 22.5 13.1 22.2 14.7 14.5 13.1 20.9 19.1 17.5 14.4 17.8 24.1 19.7 22.7 16.8 12.6 18.0 23.9 19.6 36.7 14.7 14.7 10.9 15.4 17.6 15.3 14.2 13.8 19.5 20.4 22.2 13.3 24.2 15.4 26.8 14.4 16.1 30.1 18.8 16.8 11.9 10.8 21.9 13.9 25.5 19.2 8.2 14.6 10.7 22.2 24.1 23.1 21.4 13.1 16.0 24.5 16.5 22.0 8.7 10.2 13.1 17.7 20.0 23.7 11.2 13.7 30.8 28.8 26.2 13.5 10.1 9.4 7.9 29.2 22.8 15.9 18.9 28.9 14.9 29.9 13.2 15.6 13.9 13.8 17.8 22.9 4.7 12.3 6.9 15.4 7.3 6.5 15.7 21.8 15.3 16.3 11.3 11.8 15.7 16.2 10.8 37.7 14.0 11.4 15.2 16.7 17.0 14.2 8.8 20.2 14.3 14.3 20.0 18.0 15.8 25.1 21.9 6.5 16.1 16.6 13.5 18.6 11.9 15.8 17.3 8.5 10.9 18.5 19.2 19.4 25.5 13.9 10.8 16.9 8.2 16.7 19.7 20.2 33.0 20.9 19.1 19.7 22.7 36.7 15.4 11.9 38.2 22.7 8.2 14.2 9.9 12.2 10.2 34.8 30.7 14.0 3.9 27.7 29.9 18.9 3.4 20.0 9.5 46.7 21.7 14.9 21.7 11.4 43.9 14.0 33.1 19.1 10.3 30.7 42.1 2.2 19.0 27.8 16.9 25.2 14.0 17.9 18.8 8.6 23.3 23.8 13.4 19.4 14.4 70.2 48.5 18.1 14.9 21.7 13.9 7.9 UCHL1 "PARK5, PGP9.5, Uch-L1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 225.8" "Cell type enhanced" "Detected in many" 14 "Collecting duct cells: 109.9;Distal tubular cells: 218.8;Horizontal cells: 138.2;Spermatogonia: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 3.6" "Lineage enriched" "Detected in single" 37 "B-cells: 3.6" "Cell line enhanced" "Detected in many" "EFO-21: 99.0;SCLC-21H: 98.8;U-251 MG: 90.4;U-266/84: 87.2;U-87 MG: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 440000 Cytosol Nucleoplasm "CAB002580: AB_563981, CAB079024: , HPA005993: AB_1858560" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.28e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (8.77e-3)" "unprognostic (3.56e-3)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.24e-2)" "unprognostic (7.12e-3)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.93e-4)" 8.2 40.2 52.4 8.9 65.1 2.0 3.1 17.5 225.8 4.5 6.3 11.5 0.0 5.5 6.0 1.8 2.7 5.7 6.5 5.4 53.4 97.4 14.0 2.0 2.7 6.5 62.0 57.1 15.4 6.3 1.8 30.5 2.7 100.6 5.3 4.7 6.0 3.0 4.4 7.5 2.7 8.6 5.2 38.6 2.3 2.8 8.0 8.3 0.0 3.9 0.0 4.5 5.6 2.8 3.6 0.0 0.0 0.0 0.0 0.0 0.6 0.2 56.1 11.6 0.0 1.5 1.9 0.0 58.7 30.3 20.8 21.0 11.3 0.0 0.0 99.0 29.9 31.4 0.1 21.4 0.0 8.5 0.1 8.7 0.0 0.3 0.0 44.9 0.0 0.0 10.8 0.2 16.7 0.0 34.7 0.1 0.0 0.0 0.2 11.0 0.0 0.0 0.9 33.6 0.0 63.4 0.0 24.8 0.0 31.4 0.0 98.8 62.0 0.3 0.2 0.2 13.9 0.0 0.5 0.3 1.3 0.4 0.0 90.4 46.4 87.2 0.2 96.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 52.4 65.1 17.5 92.6 53.4 97.4 62.0 57.1 100.6 8.3 0.0 1.9 0.8 0.8 1.4 19.7 2.5 0.0 12.0 5.7 109.9 7.9 2.5 218.8 3.6 2.0 2.1 0.0 0.0 0.7 0.8 15.8 2.8 2.3 0.4 4.7 138.2 4.1 11.1 0.3 4.4 34.2 1.7 3.3 1.0 0.0 22.6 4.0 0.0 16.3 7.9 39.1 0.0 7.3 6.6 90.2 1.4 1.3 0.0 0.0 0.6 UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Supported Nucleoplasm,Cytosol No No 490000 "Nucleoplasm, Cytosol" "CAB037139: AB_1841234, CAB037208: AB_1841235, HPA019678: AB_1858583" "unprognostic (4.16e-1)" "unprognostic (3.84e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (5.15e-2)" "unprognostic (6.46e-3)" "prognostic unfavorable (6.41e-4)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (9.71e-2)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.97e-1)" "unprognostic (2.76e-2)" "unprognostic (8.84e-2)" "unprognostic (3.26e-2)" 13.7 39.1 23.6 11.9 37.6 17.4 21.4 17.5 18.7 10.6 21.2 11.4 12.8 12.8 9.0 40.5 37.7 8.1 12.4 15.5 20.6 12.6 20.7 36.8 10.3 12.2 18.2 13.5 7.7 20.8 9.5 28.9 26.3 14.7 12.4 25.0 6.1 24.0 14.9 31.7 28.8 15.0 16.9 13.3 15.3 14.5 24.6 18.6 18.9 28.1 29.8 20.2 16.0 16.2 17.4 46.0 15.8 43.5 20.5 23.4 17.3 51.7 8.7 7.6 5.2 14.2 17.0 21.9 19.6 19.5 25.6 28.7 48.0 25.2 26.8 14.2 20.6 19.5 28.6 17.7 47.7 38.9 14.3 15.5 16.9 14.4 30.6 20.5 40.3 12.7 15.0 33.1 20.0 32.2 10.8 24.9 21.8 18.5 7.7 38.4 18.6 16.4 26.4 11.3 60.9 26.2 13.1 12.2 17.6 30.1 21.1 22.9 6.7 11.2 21.8 9.0 17.1 12.5 11.5 19.2 11.2 13.3 11.9 26.2 10.8 12.0 31.2 22.6 43.7 8.0 15.6 24.1 15.8 10.9 43.5 14.2 17.4 19.9 15.5 33.6 16.0 19.8 18.3 5.4 20.5 36.2 46.0 23.4 17.3 23.6 37.6 17.5 18.7 20.6 12.6 18.2 13.5 14.7 18.6 8.9 22.6 16.0 62.8 67.9 8.8 22.6 35.7 28.1 42.1 43.6 2.0 84.6 77.9 139.8 157.4 22.0 32.0 0.0 124.1 137.9 25.4 82.5 23.1 42.0 76.8 15.9 23.1 17.2 26.4 26.7 15.5 32.1 25.3 20.8 45.7 8.6 125.1 31.7 11.0 96.2 8.8 19.4 18.6 110.6 30.9 69.3 141.3 20.3 55.3 79.8 UCHL5 "CGI-70, INO80R, UCH37" ENSG00000116750 "Ubiquitin C-terminal hydrolase L5" Q9Y5K5 1 193012250-193060080 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005908, HPA006069" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Cytosol" Nucleoli "HPA005908: AB_1858585, HPA006069: " "unprognostic (3.66e-2)" "unprognostic (3.84e-3)" "unprognostic (5.17e-2)" "unprognostic (5.98e-2)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (7.41e-2)" "unprognostic (1.96e-2)" "unprognostic (1.04e-3)" "unprognostic (3.44e-3)" "unprognostic (6.92e-2)" "unprognostic (6.41e-3)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (4.33e-2)" 15.7 18.3 20.1 16.1 26.2 16.0 18.2 30.1 34.8 10.9 17.7 11.5 12.6 19.0 12.5 14.7 26.1 10.7 11.9 22.0 21.6 20.6 21.6 28.3 12.4 19.9 21.3 29.4 13.4 24.8 15.6 16.2 17.8 33.3 17.8 18.8 10.3 19.3 12.9 29.1 16.7 18.0 13.9 20.1 17.3 14.0 9.9 17.5 20.0 15.1 19.1 23.0 14.8 14.8 22.5 20.8 23.8 21.1 35.6 30.9 20.9 33.6 18.7 16.2 16.6 9.5 9.6 19.3 19.8 10.1 19.0 16.5 17.7 22.9 26.4 19.2 11.0 11.5 20.9 21.6 25.6 25.2 27.2 15.5 31.3 24.2 23.4 15.2 49.1 17.6 8.9 11.4 27.3 24.2 8.7 18.7 26.6 68.6 21.6 16.1 27.2 36.1 18.2 15.0 23.1 11.8 21.0 18.2 51.4 17.7 19.8 16.5 20.3 17.8 25.8 27.6 17.9 21.0 24.8 12.2 17.8 5.4 18.0 31.5 16.8 26.0 29.8 10.7 30.6 30.3 23.8 16.5 19.0 28.3 19.5 30.9 22.5 25.9 26.9 19.4 18.0 28.2 30.5 10.0 35.6 21.1 20.8 24.8 20.9 20.1 26.2 30.1 34.8 21.6 20.6 21.3 29.4 33.3 17.5 8.9 24.6 13.7 12.3 21.6 18.3 68.2 15.3 26.8 29.6 26.2 41.2 31.3 38.1 21.6 1.8 20.4 19.5 0.0 24.6 27.1 16.4 17.3 53.3 22.2 24.8 23.8 10.4 18.4 20.3 3.4 13.8 24.5 16.9 19.8 18.3 25.7 20.3 7.0 16.3 30.8 41.8 19.4 17.0 14.0 16.8 26.2 21.1 27.7 20.6 10.5 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097574-109110992 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatogonia: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 16.3 44.1 17.0 19.4 17.0 10.0 22.8 10.5 14.4 13.5 20.3 10.2 21.4 12.6 11.8 10.8 22.5 11.8 11.0 15.4 13.5 13.1 20.4 23.3 7.1 12.1 19.6 12.2 12.3 12.7 17.3 8.9 18.6 12.0 12.9 22.1 10.7 16.6 19.7 29.1 22.5 13.5 11.0 19.7 13.2 12.3 35.6 9.8 35.1 25.1 19.8 19.0 11.5 14.4 9.8 3.9 5.8 3.0 8.7 19.5 7.9 20.1 20.7 20.0 18.1 33.3 9.6 19.1 11.9 8.2 18.9 14.5 16.4 13.9 26.5 18.0 10.7 9.9 12.8 22.0 12.4 18.4 22.4 40.9 25.9 12.0 27.7 5.0 38.4 16.0 8.6 11.4 9.0 5.0 15.1 13.6 31.9 20.9 8.9 12.7 25.2 35.3 45.4 35.5 32.9 32.0 32.6 30.1 22.6 11.8 25.5 28.5 15.8 21.5 18.5 10.4 27.2 34.5 18.0 7.0 16.4 14.7 10.8 16.5 17.3 37.2 50.3 12.5 25.9 20.0 5.8 1.5 2.7 13.4 3.0 19.5 9.8 15.9 15.5 3.9 9.2 10.3 11.5 0.0 8.7 3.0 2.8 14.0 7.9 17.0 17.0 10.5 14.4 13.5 13.1 19.6 12.2 12.0 9.8 0.0 4.5 6.7 10.0 16.0 2.6 10.6 7.6 2.7 2.3 40.1 3.9 41.8 16.6 11.9 3.2 11.6 7.3 0.0 5.5 24.6 10.3 5.9 7.0 20.3 15.7 4.8 8.1 14.7 2.9 3.4 13.0 4.5 13.5 5.4 18.2 11.8 5.9 7.0 13.8 14.6 3.0 6.5 9.0 18.6 64.3 18.2 17.0 17.8 34.2 7.6 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 85.7" "Group enriched" "Detected in many" 7 "Hepatocytes: 119.4;monocytes: 36.9;Proximal tubular cells: 58.6" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "basophil: 11.4;neutrophil: 3.0" "Lineage enriched" "Detected in single" 43 "granulocytes: 11.4" "Group enriched" "Detected in some" 5 "CACO-2: 11.2;NB-4: 4.6;THP-1: 6.1;U-937: 6.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 790000 "HPA000728: AB_1080471, HPA076321: " "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favorable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.1 0.0 0.1 0.1 0.2 1.0 0.1 0.1 0.1 0.1 1.1 0.1 0.1 0.6 0.1 0.5 0.1 0.0 0.1 0.5 0.1 0.0 13.5 85.7 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.2 0.2 1.5 0.1 0.1 0.2 0.0 0.8 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 11.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 11.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.2 0.0 0.3 1.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.0 0.2 0.0 0.1 0.4 0.3 0.1 0.0 0.2 1.1 1.3 0.4 0.0 0.0 0.0 6.1 0.5 0.1 0.1 0.0 0.0 1.2 0.1 1.3 1.4 6.9 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 3.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.3 0.0 1.2 0.6 3.0 1.8 0.0 0.0 0.0 1.8 9.8 0.1 10.0 0.1 0.8 2.3 0.0 0.0 0.3 0.1 1.0 1.0 0.0 119.4 0.1 0.0 2.4 4.9 3.7 0.9 0.3 0.0 0.0 36.9 0.0 0.3 0.0 0.0 0.0 58.6 2.0 0.0 2.1 3.4 6.4 1.0 0.2 0.0 0.0 0.7 USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.6" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 281.4;Spermatogonia: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA028387: AB_2672578, HPA028440: AB_10603000" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.78e-3)" "unprognostic (4.05e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (6.72e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.99e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-3)" "unprognostic (5.70e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" 11.6 9.0 11.3 17.2 10.7 29.3 15.9 20.6 14.2 19.2 13.3 7.8 8.0 10.8 15.1 12.0 15.6 13.8 8.9 9.0 11.5 9.6 11.8 9.3 11.7 19.2 14.2 9.6 26.7 12.7 14.8 18.4 13.6 10.9 14.8 13.9 7.6 12.7 13.5 11.7 12.3 13.3 15.8 15.5 18.1 11.6 31.6 11.8 70.6 15.0 13.3 20.1 16.5 16.5 14.7 11.8 23.4 12.4 15.5 16.3 9.2 22.3 6.6 27.8 15.0 6.2 7.5 15.4 21.5 14.7 26.8 29.3 11.1 10.9 40.4 15.6 12.0 24.0 13.0 22.7 14.8 37.5 20.2 16.4 33.2 22.9 11.6 6.8 35.5 16.8 4.0 9.7 24.2 18.3 7.3 12.6 27.5 24.0 35.3 18.8 10.0 36.3 13.7 24.4 13.4 13.7 34.5 47.1 25.0 10.0 16.7 28.7 16.1 24.3 19.9 23.5 19.4 11.4 21.7 8.7 20.7 22.5 30.2 30.1 14.0 19.5 46.4 14.0 28.4 18.5 17.4 9.5 23.4 12.6 9.6 16.3 14.7 15.0 12.7 11.4 10.7 14.3 11.9 16.9 15.5 12.4 11.8 13.6 9.2 11.3 10.7 20.6 14.2 11.5 9.6 14.2 9.6 10.9 11.8 44.7 25.6 45.4 30.6 55.3 44.0 29.7 20.4 56.2 43.3 15.7 21.6 30.6 16.6 26.4 117.0 37.9 12.9 0.0 29.7 56.2 38.1 45.1 26.6 15.8 26.9 33.4 8.1 23.4 28.2 52.6 46.3 31.1 25.3 53.3 29.2 47.5 22.4 7.0 38.5 13.5 78.0 51.8 47.7 281.4 214.8 56.2 27.6 46.5 30.4 28.8 USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699978-84779922 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 105.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 105.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 105.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favorable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" 13.9 18.8 16.0 24.2 19.0 13.4 14.4 24.4 20.4 15.9 18.1 15.6 8.4 16.1 20.2 10.4 19.7 18.2 12.0 16.4 19.3 15.1 16.4 20.7 13.7 18.8 19.7 17.4 18.5 17.1 35.8 15.0 23.5 16.2 15.0 15.6 17.9 15.3 17.8 47.0 17.0 17.5 20.2 16.3 16.0 15.0 15.5 16.2 20.4 17.6 15.7 20.9 19.7 15.8 7.2 10.4 105.5 8.6 7.7 17.3 10.0 13.9 19.3 18.8 23.3 6.9 11.8 25.4 13.8 14.6 23.4 12.9 27.2 12.2 24.2 16.0 14.4 11.7 16.0 26.1 21.9 31.2 9.8 13.7 13.9 9.1 18.0 9.2 20.6 8.4 7.4 17.0 24.4 28.3 13.9 17.9 16.2 37.9 5.3 16.2 29.2 21.3 10.0 22.6 15.6 13.1 27.8 10.3 11.5 14.7 11.4 17.6 10.4 33.0 10.7 9.3 17.2 24.7 13.2 13.1 16.3 13.0 8.2 13.1 8.9 12.3 61.4 10.5 13.3 16.6 2.5 8.6 1.6 5.7 7.0 6.8 7.2 17.3 6.3 10.4 6.7 9.9 6.0 105.5 7.7 6.3 3.5 6.1 10.0 16.0 19.0 24.4 20.4 19.3 15.1 19.7 17.4 16.2 16.2 50.6 41.3 27.5 36.9 45.7 24.1 56.0 25.5 124.5 62.6 26.2 27.5 85.2 26.6 26.4 61.2 28.2 27.5 23.3 21.5 65.0 33.0 35.8 53.5 33.4 27.3 19.1 27.7 27.0 34.9 79.4 21.9 31.0 23.6 27.9 26.5 20.1 22.1 17.5 21.2 35.6 48.5 25.8 38.2 32.5 29.0 43.3 50.9 25.4 33.2 36.5 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232690-47248328 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.0" "Cell type enhanced" "Detected in all" 6 "Bipolar cells: 178.6;Horizontal cells: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA Nucleoplasm Cytosol "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favorable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 11.5 17.3 32.9 11.5 55.0 4.9 9.4 35.7 74.0 17.5 9.1 19.9 5.8 6.0 22.6 12.7 9.7 26.6 12.8 20.6 27.0 44.0 13.6 6.7 12.5 13.8 23.1 47.4 38.2 13.8 28.4 32.3 12.6 27.8 15.7 7.6 17.9 9.3 21.3 13.7 7.8 7.3 19.1 17.0 13.5 9.1 19.2 14.6 19.0 27.2 4.3 14.3 11.0 9.8 21.0 20.6 22.8 8.7 19.8 31.7 16.4 14.4 22.8 39.3 26.7 14.9 10.0 10.9 11.1 17.5 22.1 24.7 21.7 11.9 9.6 8.8 20.0 23.6 17.3 31.8 7.8 19.7 14.8 24.1 11.2 18.1 19.2 17.3 12.6 23.4 14.3 3.3 23.3 10.0 12.4 8.8 22.5 8.3 1.3 17.2 22.0 24.3 13.4 29.2 7.9 20.3 27.4 38.5 8.0 10.8 20.0 22.3 38.1 20.3 4.1 12.0 26.2 8.6 7.2 9.2 18.6 19.7 26.2 12.6 17.8 11.2 16.7 11.6 15.7 16.6 22.8 3.5 7.4 22.6 7.4 19.9 20.1 10.2 22.1 4.6 21.0 15.4 31.7 2.2 19.8 8.7 20.6 12.7 16.4 32.9 55.0 35.7 74.0 27.0 44.0 23.1 47.4 27.8 14.6 20.8 15.3 34.1 35.1 12.0 178.6 20.7 12.7 41.5 29.6 31.4 53.0 16.9 43.1 13.8 20.4 19.6 7.8 23.3 9.0 11.2 33.9 14.4 45.0 6.6 12.0 131.9 34.0 23.4 8.8 28.3 27.3 12.9 27.0 26.2 7.9 89.6 11.0 7.0 39.6 12.5 53.1 25.8 33.0 11.7 38.3 5.6 13.6 30.6 8.0 25.7 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066142-27171896 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 15.7 10.4 18.3 23.3 17.8 46.0 15.6 16.6 18.3 12.1 30.6 16.1 8.8 13.0 15.3 11.6 23.5 9.5 14.5 11.3 19.3 15.9 18.3 27.9 19.9 19.6 20.5 7.5 12.0 13.4 10.7 16.2 14.8 12.4 17.5 19.1 10.1 8.9 9.5 9.8 17.3 33.0 43.8 18.5 16.5 14.7 11.0 13.1 8.4 12.0 6.6 18.5 42.8 24.2 4.6 3.0 5.3 2.1 2.3 3.6 1.2 12.1 7.6 14.6 7.6 9.8 12.6 5.2 17.1 12.1 9.5 7.1 13.8 19.1 17.3 8.6 13.5 23.1 7.5 9.5 9.9 20.4 27.9 8.2 26.7 9.9 9.7 12.4 15.4 18.8 7.8 14.6 10.7 12.4 12.1 21.9 12.0 8.9 8.4 19.7 7.1 9.4 20.6 10.5 15.6 13.5 10.8 18.7 4.1 18.8 8.6 16.2 9.8 14.7 12.4 13.8 19.1 5.8 15.0 25.8 10.0 9.6 21.3 15.5 6.5 7.2 12.3 16.8 9.2 11.1 0.0 1.2 5.3 1.5 1.3 2.5 3.2 2.4 2.0 1.6 4.6 1.6 1.7 1.2 2.3 2.1 3.0 3.6 1.2 18.3 17.8 16.6 15.5 19.3 15.9 20.5 7.5 12.4 13.1 26.8 25.1 15.1 22.9 81.5 21.6 22.6 10.2 16.0 10.3 22.7 37.3 12.2 24.9 11.8 16.7 31.9 32.8 46.7 14.0 5.6 31.0 29.2 12.7 22.2 12.6 27.0 20.1 17.2 15.8 8.2 7.2 23.3 37.1 44.1 23.6 10.9 19.7 25.8 6.0 15.7 29.9 32.3 45.3 2.5 8.9 69.1 9.2 13.8 20.4 30.3 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179652755-179789401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.8;skeletal muscle: 90.3" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 182.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "MAIT T-cell: 15.4" "Lineage enriched" "Detected in many" 8 "T-cells: 15.4" "Cell line enhanced" "Detected in many" "HDLM-2: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.06e-4)" 6.4 7.5 2.0 2.3 2.8 0.8 3.5 2.9 4.1 2.7 2.1 4.6 1.5 0.7 3.2 3.8 2.6 2.5 2.5 34.8 2.0 2.3 2.3 3.4 6.0 2.5 2.1 2.1 7.2 3.0 3.3 9.8 1.9 3.0 3.0 1.8 3.1 3.3 2.1 90.3 1.8 1.7 3.7 2.5 1.6 1.6 5.6 1.3 1.7 5.5 17.1 3.2 2.6 1.9 2.0 1.9 0.0 0.4 0.0 15.4 0.7 12.5 5.4 10.2 7.8 4.6 6.4 4.9 7.4 8.5 10.9 9.2 7.9 4.4 15.5 8.3 8.9 12.3 0.9 11.4 4.5 13.0 36.6 4.9 4.1 8.1 7.4 3.3 11.4 0.0 6.9 1.6 8.5 10.8 5.3 8.7 6.1 2.0 20.0 9.0 8.2 6.9 2.1 7.9 1.1 4.9 11.9 10.1 12.7 7.4 3.5 5.8 7.5 7.1 9.5 4.3 3.0 16.4 8.2 9.4 13.2 10.5 11.3 28.4 9.7 8.1 31.7 6.1 7.7 12.2 0.0 0.2 0.0 1.3 0.4 15.4 2.0 1.3 2.9 1.5 0.6 1.0 1.0 0.0 0.0 0.4 1.9 0.6 0.7 2.0 2.8 2.9 4.1 2.0 2.3 2.1 2.1 3.0 1.3 8.9 31.0 4.3 1.7 2.3 12.7 182.3 5.1 2.7 9.1 1.8 5.9 8.7 13.3 1.0 2.1 9.7 0.3 0.0 3.7 1.6 7.1 3.4 2.3 6.8 3.7 15.9 9.2 27.6 3.1 2.0 8.6 4.7 13.5 0.0 1.6 6.3 1.6 5.8 8.9 2.7 9.7 12.9 5.3 5.1 2.1 1.4 4.2 3.2 3.8 1.6 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 1400000 "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 24.8 24.2 25.9 20.7 32.1 19.4 21.7 21.7 28.4 16.5 17.1 17.9 19.1 13.4 19.4 24.3 25.3 14.7 14.4 23.3 22.1 27.6 23.2 24.4 15.8 21.9 22.6 28.8 16.2 16.2 22.3 18.0 25.1 29.2 29.9 19.4 14.5 16.7 20.5 53.3 15.7 12.9 23.9 22.1 15.4 15.6 17.2 16.5 19.5 20.1 25.4 28.6 17.8 17.8 13.1 15.2 7.7 15.2 23.0 21.2 11.0 27.1 22.3 19.0 19.3 18.8 18.8 34.0 35.7 19.5 36.3 34.0 29.0 14.5 40.3 27.3 29.2 34.9 15.3 37.4 27.2 41.4 11.4 18.5 22.7 15.0 22.7 18.9 55.7 21.8 15.0 21.1 37.1 21.3 16.8 27.9 19.9 31.2 29.9 35.8 22.0 31.1 15.2 18.5 16.3 26.2 25.9 24.9 29.3 26.8 23.6 22.2 18.6 37.0 17.9 15.2 21.6 17.5 15.1 31.5 42.7 32.3 39.2 50.5 19.8 35.9 40.0 24.6 23.3 26.5 5.0 10.7 7.7 17.8 15.2 21.2 13.1 17.7 18.4 15.2 10.1 17.5 16.9 0.8 23.0 11.4 11.1 16.7 11.0 25.9 32.1 21.7 27.1 22.1 27.6 22.6 28.8 29.2 16.5 20.8 33.1 28.2 36.7 52.1 52.7 40.0 22.9 42.8 51.2 41.8 29.5 80.1 38.1 58.5 41.3 39.3 15.4 23.3 46.8 58.4 42.1 56.1 33.5 39.4 45.0 109.7 21.2 28.3 30.4 14.7 29.4 39.1 33.7 54.1 19.4 35.6 58.1 19.5 43.2 43.1 50.1 0.0 45.7 26.2 61.2 45.8 113.4 38.8 27.3 39.1 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 68.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Plasma membrane,Cytosol" NA NA 280000 Cytosol "Plasma membrane" "HPA006237: AB_1080502, HPA006428: AB_2667588, HPA071014: AB_2686333" "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 23.1 16.8 11.5 22.5 11.9 88.9 17.8 21.1 15.7 14.5 14.5 5.2 11.9 11.4 12.7 12.4 16.1 14.1 11.2 15.2 9.6 6.2 13.8 20.4 23.8 26.2 11.6 9.4 22.5 15.8 18.9 22.5 31.0 14.9 12.4 13.8 7.6 16.2 10.7 28.5 23.0 19.7 16.3 16.2 35.6 14.3 20.0 11.0 33.1 14.1 15.4 18.9 18.4 17.9 5.7 6.0 68.5 14.2 3.3 12.1 4.8 9.4 8.9 8.9 7.8 14.1 16.5 16.0 15.4 13.7 13.6 12.2 8.9 9.5 10.1 8.8 13.2 5.8 10.4 11.9 13.4 16.0 11.2 7.3 13.9 7.6 6.8 13.6 22.0 33.8 12.0 14.0 16.1 14.3 12.8 16.2 10.3 45.0 19.6 12.6 10.5 13.1 11.1 13.0 8.6 13.2 8.4 9.4 16.3 12.7 10.9 11.3 5.4 17.8 11.3 8.7 9.7 15.0 13.2 19.3 10.6 10.6 16.5 9.5 9.3 10.4 11.6 12.2 17.9 12.0 27.2 14.2 13.8 3.4 7.3 3.5 5.7 4.6 3.2 4.9 4.7 5.9 3.5 68.5 3.3 5.8 6.0 12.1 4.8 11.5 11.9 21.1 15.7 9.6 6.2 11.6 9.4 14.9 11.0 35.7 31.3 91.0 32.3 52.2 54.5 62.7 17.8 42.8 59.1 22.7 104.1 25.1 10.0 31.3 139.8 44.6 32.3 93.5 36.2 36.1 49.5 31.6 85.6 42.0 41.1 39.7 40.4 22.1 108.1 130.5 57.2 94.6 50.6 36.1 22.9 24.4 41.2 45.6 27.6 19.4 146.4 38.8 56.5 62.9 41.8 67.2 55.0 65.0 23.3 54.9 USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Early spermatids: 399.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA021140: AB_1858668" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (5.92e-2)" "unprognostic (5.79e-3)" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (5.78e-2)" "unprognostic (7.40e-2)" "unprognostic (8.73e-2)" "unprognostic (8.65e-2)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" 25.4 21.7 24.4 27.4 24.2 20.4 22.8 32.4 23.1 24.2 24.3 13.5 23.6 20.4 22.6 28.2 27.1 19.4 17.0 23.8 23.8 22.6 28.4 34.0 16.8 20.7 25.8 19.5 27.3 23.6 31.6 41.6 45.9 25.3 26.0 22.3 13.3 20.6 28.8 35.8 16.1 33.2 26.2 28.6 29.1 20.8 20.1 25.3 37.6 28.4 25.6 25.5 30.8 17.1 30.9 23.5 21.2 20.5 19.9 26.2 10.1 22.0 8.8 14.1 12.6 10.0 16.5 13.3 21.6 14.4 15.0 14.3 11.0 14.4 22.5 6.5 20.7 22.9 10.1 17.4 15.7 19.6 21.6 18.5 30.1 10.7 12.2 14.9 29.5 16.7 14.1 16.6 19.5 18.1 11.1 14.3 12.9 24.7 39.9 17.3 10.1 18.1 10.8 15.0 18.0 11.5 12.2 34.8 25.8 12.3 16.0 15.3 16.3 14.0 22.4 18.9 10.0 15.4 20.2 14.4 17.6 21.8 16.1 22.1 34.1 46.8 23.7 18.3 21.4 17.4 21.2 16.2 20.9 25.4 16.1 19.8 26.4 23.9 22.8 14.9 30.9 26.2 24.8 15.5 19.9 20.5 23.5 24.5 10.1 24.4 24.2 32.4 23.1 23.8 22.6 25.8 19.5 25.3 25.3 80.4 84.0 98.9 106.9 50.8 161.8 74.6 53.5 112.4 87.6 50.6 84.4 70.3 112.7 61.8 399.0 40.7 72.4 23.3 103.3 66.4 62.2 82.7 136.5 77.6 53.4 68.3 79.3 46.1 54.6 89.6 81.1 59.7 59.1 95.6 64.7 103.3 77.6 75.8 81.7 60.8 186.0 58.2 71.0 80.0 64.3 56.2 135.5 69.2 70.2 111.6 USP17L1 USP17L1P ENSG00000230549 "Ubiquitin specific peptidase 17-like family member 1" Q7RTZ2 8 7332387-7333979 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "brain: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.0;JURKAT: 1.4" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L10 ENSG00000231396 "Ubiquitin specific peptidase 17-like family member 10" C9JJH3 4 9210657-9212608 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L11 ENSG00000233136 "Ubiquitin specific peptidase 17-like family member 11" C9JVI0 4 9215405-9217356 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 1.0;fallopian tube: 1.2;thyroid gland: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.5;JURKAT: 1.4;NTERA-2: 1.6" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.4 0.0 0.0 0.0 0.5 0.0 0.0 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L12 ENSG00000227551 "Ubiquitin specific peptidase 17-like family member 12" C9JPN9 4 9220152-9221744 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L13 ENSG00000232399 "Ubiquitin specific peptidase 17-like family member 13" C9JLJ4 4 9224896-9226847 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.2" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L15 ENSG00000223569 "Ubiquitin specific peptidase 17-like family member 15" C9J2P7 4 9234385-9236334 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 1.0;epididymis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.2" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.1 0.3 0.4 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L17 ENSG00000249104 "Ubiquitin specific peptidase 17-like family member 17" D6RBQ6 4 9243879-9245830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in single" "thyroid gland: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.2;NTERA-2: 1.4" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L18 ENSG00000250844 "Ubiquitin specific peptidase 17-like family member 18" D6R9N7 4 9248630-9250581 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.2" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L19 ENSG00000248920 "Ubiquitin specific peptidase 17-like family member 19" D6RCP7 4 9253378-9255329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17-like family member 2" Q6R6M4 8 12137168-12139077 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEK 293: 1.3" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" "unprognostic (2.01e-1)" 0.1 0.4 0.1 0.1 0.5 0.0 0.2 0.8 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 1.0 1.1 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L20 ENSG00000250745 "Ubiquitin specific peptidase 17-like family member 20" D6RJB6 4 9258124-9260075 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;hTERT-HME1: 1.1" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L21 ENSG00000249811 "Ubiquitin specific peptidase 17-like family member 21" D6R901 4 9262872-9264823 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L22 ENSG00000248933 "Ubiquitin specific peptidase 17-like family member 22" D6RA61 4 9267619-9269570 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.0" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L24 ENSG00000232264 "Ubiquitin specific peptidase 17-like family member 24" Q0WX57 4 9325165-9327116 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L25 ENSG00000230430 "Ubiquitin specific peptidase 17-like family member 25" Q0WX57 4 9329911-9331862 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L26 ENSG00000229579 "Ubiquitin specific peptidase 17-like family member 26" Q0WX57 4 9334658-9336609 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L27 ENSG00000235780 "Ubiquitin specific peptidase 17-like family member 27" Q0WX57 4 9344148-9345740 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L28 ENSG00000231051 "Ubiquitin specific peptidase 17-like family member 28" Q0WX57 4 9348893-9350485 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L29 ENSG00000231637 "Ubiquitin specific peptidase 17-like family member 29" Q0WX57 4 9353638-9355230 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L3 "USP17B, USP17F" ENSG00000225327 "Ubiquitin specific peptidase 17-like family member 3" A6NCW0 8 7976393-7977985 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L30 ENSG00000228856 "Ubiquitin specific peptidase 17-like family member 30" Q0WX57 4 9363129-9364721 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L5 ENSG00000227140 "Ubiquitin specific peptidase 17-like family member 5" A8MUK1 4 9339403-9340995 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP19 "KIAA0891, ZMYND9" ENSG00000172046 "Ubiquitin specific peptidase 19" O94966 3 49108046-49120938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (3.23e-2)" "unprognostic (2.12e-1)" "unprognostic (5.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.00e-3)" "unprognostic (2.69e-1)" "unprognostic (3.65e-2)" "unprognostic (2.31e-2)" "unprognostic (1.26e-1)" "prognostic favorable (7.05e-9)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-3)" "unprognostic (7.54e-2)" 13.9 19.5 10.3 14.6 12.2 16.2 14.9 19.4 37.1 17.0 16.3 12.5 19.6 14.6 18.7 17.9 14.3 17.2 19.9 17.9 10.3 9.4 14.8 16.5 14.7 13.8 11.9 9.5 17.2 15.2 22.4 13.2 17.6 11.4 14.2 10.9 14.9 24.7 26.0 57.3 18.4 16.1 13.9 8.5 17.5 15.1 14.9 11.7 23.0 17.7 15.2 12.6 17.4 14.1 5.1 6.7 12.3 5.7 4.3 8.4 5.3 8.3 12.0 14.4 20.3 17.7 12.2 18.4 9.4 12.6 17.6 13.3 12.0 12.8 18.0 9.6 11.8 17.5 11.1 18.2 13.6 7.3 14.1 14.0 17.5 24.1 11.0 18.4 19.8 18.5 17.3 10.6 16.6 12.1 12.3 11.5 16.1 13.7 13.6 8.8 10.8 18.7 20.5 27.3 12.5 17.6 9.1 10.7 20.8 10.9 15.9 7.9 22.7 13.9 18.2 16.3 12.5 12.3 26.4 9.1 11.7 14.3 17.3 14.2 34.4 33.3 15.9 15.1 15.7 14.5 12.3 4.9 7.5 7.2 5.3 6.8 4.6 5.8 8.4 6.7 5.1 5.7 6.2 8.8 4.3 5.7 3.0 4.1 5.3 10.3 12.2 19.4 37.1 10.3 9.4 11.9 9.5 11.4 11.7 11.9 9.7 2.9 4.0 5.6 11.4 9.6 2.5 10.7 10.3 7.0 17.7 8.5 5.0 6.6 2.7 7.1 13.1 0.0 6.7 4.4 5.8 4.6 2.3 12.1 7.8 12.7 8.7 7.4 6.1 4.1 12.0 8.4 3.3 1.8 11.3 7.7 9.8 11.8 11.7 6.3 11.2 12.9 5.2 10.5 10.0 4.6 11.3 6.4 10.9 2.6 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381726 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 79.9" "Group enriched" "Detected in many" 5 "Early spermatids: 399.1;Late spermatids: 802.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enriched" "Detected in many" 4 "U-266/70: 35.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 3.1 4.8 6.9 1.4 12.2 1.5 1.6 12.6 16.1 2.5 5.9 10.0 0.0 7.9 2.6 6.4 5.9 7.0 2.2 26.8 5.7 3.1 29.7 10.6 2.2 0.7 5.7 6.2 2.9 10.1 18.4 7.6 1.3 6.7 2.3 3.9 19.1 3.2 2.4 79.9 4.6 11.7 4.2 3.8 0.8 2.7 36.1 8.8 0.0 2.2 25.2 1.0 1.9 2.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 3.5 0.3 0.5 2.0 0.1 0.1 0.8 0.4 0.2 0.0 0.4 3.6 0.5 6.1 1.1 0.6 0.9 0.6 4.8 1.8 0.1 4.2 0.6 1.7 2.6 7.5 1.7 0.0 1.7 0.6 0.3 0.4 1.2 0.8 0.3 4.6 8.4 0.5 1.0 2.4 0.0 0.4 0.9 1.2 0.8 0.0 1.3 0.9 2.8 0.2 7.4 2.2 2.1 1.6 0.4 1.1 5.4 3.7 0.0 0.0 0.9 0.5 0.6 35.2 7.7 0.1 0.0 1.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.0 0.3 0.3 6.9 12.2 12.6 16.1 5.7 3.1 5.7 6.2 6.7 8.8 3.0 2.4 0.0 4.5 2.2 73.3 74.6 5.1 42.8 9.1 5.2 90.3 0.3 96.2 2.6 399.1 2.2 31.5 0.0 1.4 0.5 4.6 1.0 0.0 19.8 13.2 9.5 0.0 1.3 1.5 802.9 6.1 1.3 0.0 0.0 1.6 37.9 1.5 10.5 6.7 24.9 128.7 19.4 18.6 19.9 14.9 3.4 1.1 1.5 2.2 2.0 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881838 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 42.3;K-562: 25.9;MOLT-4: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (2.48e-4)" "prognostic favorable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favorable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favorable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 7.8 13.2 10.5 15.2 14.6 24.4 8.5 23.0 19.6 13.2 12.1 12.7 10.2 9.7 13.3 6.2 9.3 11.6 12.5 8.8 10.5 13.7 8.0 7.3 9.1 19.6 9.6 16.1 16.8 12.9 11.5 19.0 8.0 11.9 14.9 6.1 10.8 13.7 17.2 10.2 14.0 11.8 20.0 8.8 14.6 10.2 14.0 8.8 51.5 19.3 4.2 15.3 15.6 10.0 3.8 2.4 4.8 1.7 9.0 10.7 5.4 2.5 2.5 4.4 6.0 5.8 5.0 6.3 4.1 3.5 3.2 2.2 2.1 2.8 3.5 3.6 4.0 3.6 6.5 2.6 3.0 1.3 19.0 3.5 6.5 6.8 1.4 4.1 6.1 4.8 4.4 4.4 4.2 3.1 5.6 3.4 42.3 25.9 4.4 1.9 6.8 23.8 14.5 3.5 5.4 6.0 4.0 5.0 5.9 2.5 2.8 1.0 4.9 4.8 6.2 3.9 2.7 6.4 8.5 5.0 3.5 1.6 4.7 2.7 4.3 6.3 2.4 7.0 8.0 3.3 1.0 1.7 4.8 8.6 1.4 9.3 3.7 8.8 8.3 2.4 3.8 10.4 8.9 2.8 9.0 1.3 2.1 10.7 5.4 10.5 14.6 23.0 19.6 10.5 13.7 9.6 16.1 11.9 8.8 8.9 8.6 3.2 2.3 2.5 7.9 5.9 2.5 4.0 2.3 1.8 3.9 5.1 3.3 2.2 1.1 2.4 4.0 0.0 3.4 2.1 3.8 3.0 1.1 5.6 3.0 9.5 8.1 7.4 2.1 2.8 5.8 3.1 3.3 3.6 4.6 5.8 2.3 3.7 4.6 2.2 5.9 0.0 6.2 12.2 4.4 1.8 5.1 11.3 5.1 1.4 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favorable (3.35e-5)" 11.8 16.4 22.1 12.8 21.2 15.3 19.1 23.6 24.8 18.1 16.1 25.5 14.0 15.5 19.7 14.6 18.3 33.3 14.1 13.7 20.9 12.1 15.4 10.6 14.0 16.7 26.4 14.1 28.3 19.0 24.4 17.2 15.2 20.5 18.1 13.1 17.1 19.0 25.3 19.4 23.5 15.4 15.1 17.0 18.7 16.0 17.0 22.9 16.0 24.5 9.6 15.6 17.9 19.2 14.1 12.0 18.3 11.1 13.4 17.2 10.7 7.4 12.9 16.9 16.3 13.5 11.3 10.4 5.5 9.0 15.2 11.9 11.8 14.7 9.8 9.5 6.8 9.5 12.9 10.9 10.7 8.4 18.6 18.4 11.6 18.6 9.2 9.8 10.3 8.7 9.5 14.4 10.4 15.1 17.2 10.7 21.7 17.2 13.6 9.7 13.7 18.2 16.2 15.8 14.6 16.4 17.3 5.6 16.4 8.9 8.9 15.4 19.9 10.3 10.9 8.3 13.2 23.9 16.7 6.3 10.9 9.8 7.6 9.4 27.6 21.3 14.5 10.0 8.9 9.8 13.0 11.1 18.3 14.9 7.1 17.2 12.8 13.8 15.4 12.0 14.1 16.0 14.6 9.6 13.4 7.7 12.0 13.3 10.7 22.1 21.2 23.6 24.8 20.9 12.1 26.4 14.1 20.5 22.9 0.0 3.0 1.7 1.5 1.3 3.9 2.2 10.2 10.7 3.4 1.8 5.9 3.6 1.7 1.4 0.6 2.8 2.0 0.0 2.0 2.1 2.4 2.0 2.3 1.7 1.9 0.0 5.2 6.2 7.6 0.4 4.6 1.7 1.7 0.0 4.1 3.0 1.7 2.9 3.9 1.8 4.4 6.5 1.9 3.6 2.7 1.3 2.6 2.5 3.7 1.4 USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999593-21043760 "Enzymes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA044980: AB_10794503" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (7.67e-2)" "unprognostic (6.19e-2)" "unprognostic (4.72e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.17e-2)" "unprognostic (7.81e-2)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (5.68e-2)" "prognostic favorable (1.53e-7)" "unprognostic (8.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-2)" 22.5 33.0 40.7 21.5 49.5 25.9 24.6 66.1 66.4 26.8 23.6 31.9 25.1 18.9 36.7 29.3 21.9 33.9 23.0 44.1 38.7 47.6 27.7 22.9 26.1 25.1 31.0 40.7 45.6 24.5 47.4 32.2 22.4 35.1 27.5 20.5 28.7 20.0 29.5 47.6 22.1 21.1 31.2 24.8 23.7 22.7 20.2 23.7 41.2 32.8 24.8 27.3 25.1 23.2 13.7 12.1 13.4 13.3 8.9 15.5 6.9 19.6 35.6 34.6 29.7 20.2 21.0 16.5 22.6 17.4 20.4 17.4 41.0 8.9 26.9 21.8 34.7 13.8 21.1 33.5 27.0 30.6 12.8 23.2 22.3 23.7 19.9 24.0 24.5 19.5 23.1 16.2 23.1 24.3 23.3 25.4 17.7 25.3 9.8 28.8 20.2 34.3 11.7 17.8 23.3 11.7 38.0 54.8 18.3 18.8 28.9 16.7 34.4 29.2 12.1 23.7 99.0 20.3 14.5 32.2 20.9 27.8 21.4 30.5 10.5 14.1 89.5 21.2 13.1 32.2 6.8 13.3 12.6 11.0 9.8 11.1 10.9 11.7 10.9 12.1 13.7 15.5 14.6 13.4 8.9 12.2 10.2 7.8 6.9 40.7 49.5 66.1 66.4 38.7 47.6 31.0 40.7 35.1 23.7 38.7 45.6 40.4 39.5 29.3 90.6 20.9 58.6 29.4 35.2 57.6 88.4 42.1 19.9 47.1 31.0 40.9 35.1 0.0 50.6 33.9 44.7 49.2 29.0 55.2 34.1 111.2 84.7 78.0 53.0 39.2 47.2 23.7 33.7 24.4 42.7 58.7 59.0 38.6 67.5 45.1 54.5 12.9 38.8 14.2 16.6 25.5 55.0 23.0 46.6 38.9 USP24 KIAA1057 ENSG00000162402 "Ubiquitin specific peptidase 24" Q9UPU5 1 55066359-55215113 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.0" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026723, HPA028428, HPA067124" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA026723: AB_10599851, HPA028428: AB_10600991, HPA067124: AB_2685785" "unprognostic (2.28e-1)" "unprognostic (9.81e-3)" "unprognostic (4.70e-3)" "unprognostic (4.86e-3)" "unprognostic (9.31e-3)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.34e-7)" "unprognostic (2.04e-1)" "unprognostic (6.93e-2)" "unprognostic (2.98e-1)" "unprognostic (5.08e-2)" "unprognostic (1.86e-1)" "unprognostic (8.12e-2)" "unprognostic (1.79e-1)" "unprognostic (6.42e-2)" "unprognostic (4.12e-2)" "unprognostic (1.64e-1)" 12.3 7.6 7.5 12.1 8.8 30.1 10.6 20.1 8.5 7.8 10.2 6.8 10.6 5.0 10.1 7.0 7.7 6.9 7.0 14.7 7.9 6.4 10.4 9.3 7.6 12.7 8.0 5.6 10.9 7.3 15.5 16.9 5.8 6.9 7.6 8.5 5.1 9.7 10.7 46.0 8.9 8.7 7.3 6.2 10.9 7.8 4.9 8.7 16.4 7.4 11.5 12.7 9.7 13.7 6.0 10.5 5.9 2.2 3.8 4.5 1.1 17.7 9.8 12.3 6.6 16.0 14.1 14.2 7.9 9.9 11.4 11.9 13.9 6.3 14.3 8.7 14.6 23.4 14.4 16.3 13.3 17.9 14.9 9.8 28.6 21.4 16.3 9.5 19.7 22.2 12.3 11.8 17.2 19.6 11.0 10.3 14.6 26.3 6.0 15.1 4.2 11.8 10.5 18.0 8.6 11.9 12.3 15.7 6.2 19.8 12.0 10.8 7.6 13.4 9.6 11.7 19.5 6.7 9.8 13.9 10.4 10.1 12.5 12.5 7.6 5.6 18.8 9.9 16.4 9.3 5.9 2.0 2.5 4.5 1.8 2.8 4.8 3.5 3.5 1.8 6.0 3.2 4.2 2.3 3.8 2.2 10.5 1.9 1.1 7.5 8.8 20.1 8.5 7.9 6.4 8.0 5.6 6.9 8.7 14.9 18.3 14.2 7.0 13.3 12.9 28.1 10.2 8.1 15.9 12.2 68.7 3.6 0.0 8.8 0.4 13.1 6.8 0.0 8.7 6.5 9.6 9.6 12.7 10.9 8.4 36.5 16.6 10.4 17.5 1.3 10.9 12.2 10.1 12.6 16.4 7.1 9.9 11.5 7.4 4.5 16.7 6.5 10.5 8.6 5.8 15.1 1.3 17.1 14.9 8.6 USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15730025-15880069 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 124.6;Late spermatids: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol NA NA Cytosol "HPA018297: AB_1858672, HPA024142: AB_1858673" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (6.90e-2)" "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "unprognostic (1.40e-1)" "unprognostic (8.24e-3)" "unprognostic (2.34e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-2)" 14.9 8.5 11.0 14.2 15.5 12.4 28.7 11.3 11.1 17.5 11.8 6.6 17.8 6.5 20.7 14.5 12.6 10.6 10.1 17.8 9.9 5.8 12.9 10.4 22.1 14.8 7.6 7.1 14.5 8.2 8.1 8.4 17.7 7.7 12.9 8.6 7.8 11.4 13.6 56.3 8.3 12.3 19.2 7.3 11.6 9.0 26.1 7.5 16.5 10.5 14.6 9.6 13.8 18.1 3.1 2.8 5.8 2.9 2.3 7.2 1.6 13.2 10.0 9.5 1.4 17.6 26.3 11.2 9.5 9.5 7.1 9.0 8.8 7.6 14.3 14.1 15.0 10.8 7.1 7.3 12.6 9.9 14.2 8.4 11.7 10.6 6.7 29.2 15.4 5.4 17.0 15.4 11.4 33.2 18.7 24.9 13.1 15.0 27.1 12.8 5.5 17.6 2.9 11.7 5.3 8.9 13.5 8.8 10.8 19.3 3.6 2.1 5.7 13.6 11.5 8.8 12.1 6.1 9.1 23.6 11.1 7.2 11.6 5.3 7.9 4.8 11.4 7.2 6.9 8.1 0.0 2.9 3.6 4.0 2.8 4.4 3.1 3.4 7.2 2.5 2.2 3.2 4.8 5.8 2.3 2.5 2.8 4.4 1.6 11.0 15.5 11.3 11.1 9.9 5.8 7.6 7.1 7.7 7.5 53.6 22.7 11.5 16.1 15.1 5.7 52.1 10.2 25.4 31.8 21.0 3.9 27.3 5.0 7.8 124.6 19.1 12.8 0.0 11.4 6.8 16.0 19.0 5.8 17.3 11.9 4.8 9.2 17.2 23.7 145.9 17.5 18.8 15.1 6.4 11.9 4.2 10.4 7.0 12.0 12.2 6.0 19.4 15.5 9.8 5.3 16.8 27.7 17.5 10.2 20.5 USP26 ENSG00000134588 "Ubiquitin specific peptidase 26" Q9BXU7 X 133024631-133097109 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 3.8" "Cell type enriched" "Detected in single" 14 "Spermatogonia: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "HPA000424, HPA027310" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA000424: , HPA027310: " "unprognostic (7.92e-4)" "unprognostic (3.59e-2)" "unprognostic (1.99e-2)" "unprognostic (2.08e-1)" 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.1 0.1 3.8 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.0 0.0 0.5 0.4 0.5 0.4 0.1 0.1 0.2 0.2 0.7 0.1 0.2 0.1 0.7 0.1 0.1 0.0 0.1 0.7 0.1 0.2 0.3 1.0 0.3 1.0 0.3 0.1 0.1 0.0 1.5 0.6 0.4 0.1 0.3 0.1 0.4 0.4 0.4 0.2 0.2 0.1 0.8 0.4 0.2 0.3 0.4 0.1 0.0 0.9 0.5 0.5 0.2 0.1 0.1 0.2 1.0 0.1 0.7 0.3 0.9 0.1 0.3 0.4 0.9 0.3 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.7 0.0 0.0 0.0 0.0 0.0 USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27, X-linked" A6NNY8 X 49879948-49882565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 17.9;Ciliated cells: 24.1;Cytotrophoblasts: 34.3;Syncytiotrophoblasts: 21.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA077264: AB_2686831" "unprognostic (4.12e-2)" "unprognostic (9.58e-3)" "unprognostic (2.29e-1)" "unprognostic (4.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.14e-4)" "unprognostic (3.10e-3)" "unprognostic (3.91e-2)" "unprognostic (1.31e-2)" "prognostic favorable (9.31e-4)" "unprognostic (5.37e-2)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-1)" 1.8 3.3 1.8 5.9 2.9 0.3 7.7 1.7 7.4 3.9 5.9 4.8 2.2 1.1 12.7 4.1 3.1 4.7 3.8 3.9 2.2 3.5 3.5 6.1 1.9 1.3 3.2 8.8 3.2 4.1 0.8 15.5 2.8 4.1 1.7 4.1 5.2 3.9 7.5 2.6 4.7 3.9 1.3 2.0 1.9 3.8 1.9 2.8 3.2 3.6 2.2 3.7 3.1 1.7 1.0 0.7 0.7 0.3 1.3 0.4 1.8 4.7 5.5 6.3 5.2 4.3 4.6 2.1 3.4 2.4 2.0 8.5 2.1 1.2 2.0 5.4 7.9 3.0 7.8 5.2 3.5 2.4 3.7 2.0 1.4 7.7 3.5 0.6 4.3 6.0 3.6 3.4 3.4 5.9 3.3 5.5 3.9 2.0 3.8 4.5 2.9 1.7 6.0 3.5 3.3 3.1 4.8 0.4 3.9 1.8 1.4 4.1 4.0 3.8 4.9 17.9 4.4 1.4 2.5 2.8 5.4 4.8 0.8 1.9 0.5 0.8 3.2 1.7 3.0 0.7 0.4 0.1 0.6 0.4 0.8 0.6 0.5 0.3 1.0 1.7 0.8 0.6 0.7 0.3 0.7 0.4 1.3 0.4 17.9 13.3 0.0 4.1 2.6 9.7 2.3 0.0 24.1 13.6 0.0 0.0 34.3 5.0 1.1 0.0 3.1 0.7 0.0 0.6 2.0 1.8 2.5 2.3 1.7 3.4 4.8 4.1 3.1 0.3 0.0 2.0 1.1 0.0 1.0 1.2 10.2 1.2 0.0 3.2 2.6 2.0 6.5 1.7 0.0 1.4 1.9 21.9 1.3 1.7 1.7 USP28 KIAA1515 ENSG00000048028 "Ubiquitin specific peptidase 28" Q96RU2 11 113797874-113875570 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 40.1;skeletal muscle: 50.2" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006778, HPA006779" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA006778: AB_1080520, HPA006779: AB_1080517" "unprognostic (2.54e-1)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" "unprognostic (3.72e-2)" "unprognostic (5.51e-2)" "unprognostic (2.30e-1)" "unprognostic (9.73e-3)" "unprognostic (3.00e-1)" "unprognostic (2.04e-3)" "unprognostic (1.82e-3)" "unprognostic (3.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.11e-2)" "unprognostic (2.06e-2)" "unprognostic (9.03e-2)" "unprognostic (1.35e-3)" "unprognostic (5.03e-2)" 3.9 3.4 4.8 8.6 5.7 2.4 5.7 26.4 8.6 11.6 5.1 4.9 14.0 4.7 6.0 6.0 5.7 5.0 4.0 40.1 5.0 4.8 5.1 5.6 5.1 7.2 6.8 4.5 7.5 4.1 10.6 9.7 3.9 4.8 8.9 6.0 5.7 5.7 12.2 50.2 3.5 5.1 11.6 6.4 6.9 4.4 5.5 3.8 3.6 5.1 10.1 7.7 7.1 4.6 10.3 4.1 2.1 3.7 17.9 16.2 6.0 8.6 9.7 13.1 17.3 10.8 10.7 9.3 6.4 8.8 8.6 14.8 14.4 12.5 11.5 14.6 8.6 19.9 17.0 18.5 12.0 12.0 12.8 8.4 6.1 6.8 7.7 6.6 7.8 6.1 6.4 9.1 10.0 11.9 12.6 15.5 5.7 10.5 7.5 9.0 4.4 5.9 12.8 15.7 16.0 7.0 14.7 18.3 13.9 9.5 8.5 5.7 6.2 15.2 5.2 4.9 42.9 12.6 2.7 8.2 9.6 14.4 8.7 6.5 5.1 7.3 9.7 0.9 15.3 6.2 0.1 3.2 2.1 16.2 2.4 8.4 10.3 4.1 11.4 4.1 8.4 2.7 9.4 0.9 17.9 3.7 1.2 5.6 6.0 4.8 5.7 26.4 8.6 5.0 4.8 6.8 4.5 4.8 3.8 8.9 9.1 10.0 6.9 1.4 16.1 130.6 5.1 14.7 10.3 5.2 17.7 3.5 5.0 5.7 1.4 4.3 5.1 0.0 3.4 3.7 4.7 6.2 1.1 6.7 3.9 4.8 4.7 6.2 4.1 1.4 6.4 6.5 1.7 5.4 10.3 10.1 4.4 3.5 13.1 6.3 20.2 6.5 5.2 10.8 10.0 1.8 0.9 24.5 9.2 4.9 USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "blood: 4.1;bone marrow: 2.7;pancreas: 2.1;skin 1: 2.3;testis: 8.4" "Group enriched" "Detected in some" 9 "Collecting duct cells: 1.8;Early spermatids: 1.7;Spermatocytes: 4.8;Spermatogonia: 1.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.2" "Not detected" "Not detected" HPA076515 Enhanced NA NA "HPA076515: " "unprognostic (1.32e-1)" 0.1 0.1 0.2 0.0 0.2 2.7 0.1 0.1 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.2 0.1 0.1 0.1 0.3 0.1 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.2 2.3 0.1 0.0 0.1 0.1 0.4 8.4 0.4 0.0 0.7 0.1 1.1 1.9 4.1 1.1 1.2 0.8 0.6 0.1 0.7 0.8 0.3 0.0 0.0 3.3 0.0 0.0 0.1 0.1 1.7 0.0 0.9 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.0 3.2 0.8 0.0 0.0 1.1 0.0 2.0 0.9 1.0 1.4 0.0 0.0 0.0 1.0 0.3 0.9 0.0 0.7 0.0 1.2 0.0 0.5 1.0 0.9 0.0 1.0 0.0 2.1 2.1 0.7 0.6 0.4 0.3 1.2 0.8 1.3 1.5 1.3 0.5 0.0 0.0 1.6 0.5 1.5 0.5 0.8 0.0 3.1 1.1 1.1 0.8 0.7 0.6 0.5 0.7 0.3 0.3 1.1 0.7 0.7 4.1 1.2 0.4 1.9 0.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.5 0.0 0.0 0.0 0.0 0.1 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 33.4" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" No No Nucleoplasm "Midbody ring" "HPA053275: AB_2682096, HPA060513: AB_2684299, HPA077975: AB_2732365" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.38e-4)" 16.0 9.0 5.9 20.4 6.5 38.6 21.3 33.4 6.6 12.7 19.1 6.0 16.8 16.2 18.1 13.3 13.6 10.4 14.2 7.6 6.6 4.4 12.9 10.8 17.5 28.2 8.1 3.9 19.5 27.1 7.1 8.2 10.2 7.9 12.4 11.5 8.2 18.5 14.8 12.4 15.9 19.0 16.1 8.0 23.6 14.7 10.3 7.8 22.7 12.5 11.4 22.5 21.3 17.9 11.4 20.6 52.6 28.1 7.2 12.9 13.4 9.2 30.2 15.6 9.8 7.7 12.6 13.8 7.9 9.9 7.7 9.5 11.8 17.3 9.4 12.6 7.9 5.1 11.7 14.6 12.3 7.5 15.3 7.9 10.6 10.8 12.7 6.6 6.3 12.8 9.0 16.3 9.3 16.2 7.8 16.7 16.9 14.1 12.0 4.9 14.3 13.1 10.2 19.7 18.9 13.1 19.2 9.4 16.6 9.2 31.7 13.7 10.6 4.9 16.2 9.7 8.9 9.7 12.3 15.8 8.9 18.6 5.2 10.5 10.8 19.9 20.8 8.6 17.5 7.4 28.8 28.1 3.5 8.4 22.6 9.3 10.3 11.9 8.6 20.6 11.4 12.9 9.3 52.6 7.2 18.7 4.1 9.1 13.4 5.9 6.5 33.4 6.6 6.6 4.4 8.1 3.9 7.9 7.8 35.7 60.4 35.8 31.2 46.8 31.1 9.1 20.4 36.1 43.3 15.7 11.8 17.3 34.9 36.4 19.7 20.3 33.9 0.0 32.3 46.8 16.4 35.8 25.5 20.8 22.8 12.7 42.1 11.1 75.5 53.6 14.7 64.4 40.5 27.1 32.5 24.6 35.0 31.7 17.3 19.9 17.8 12.9 25.2 10.2 41.8 51.6 28.5 37.4 34.7 33.1 USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088026 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved NA NA "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favorable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" 11.7 18.9 12.7 9.0 17.6 12.2 10.4 11.9 21.0 10.3 13.2 29.2 13.6 14.9 12.4 8.5 9.2 11.1 8.4 9.0 10.3 10.6 12.4 21.7 8.9 10.4 16.6 7.8 17.5 12.4 14.7 13.0 6.7 16.0 9.4 11.3 16.4 10.1 12.4 16.4 13.6 14.1 8.6 14.3 9.8 8.5 21.3 16.3 8.7 11.1 5.3 7.1 10.8 8.1 14.2 12.2 12.7 11.0 18.3 17.4 6.0 4.6 3.6 9.5 8.2 6.7 7.7 5.3 5.2 6.8 6.1 5.4 4.2 3.6 11.7 4.4 5.1 5.6 5.2 8.3 5.4 7.0 13.5 10.4 3.8 3.2 6.0 7.2 7.4 4.2 9.2 6.6 5.4 5.3 15.8 7.0 12.1 5.6 5.7 5.1 5.4 11.7 4.2 3.0 5.6 10.1 12.7 6.8 7.0 4.9 5.6 8.7 7.7 7.0 5.3 5.5 7.3 13.1 5.8 5.0 5.6 3.1 5.4 3.4 14.3 11.9 17.5 6.0 4.5 6.2 9.5 7.1 12.7 15.4 11.0 17.4 14.2 12.9 14.3 4.6 14.2 13.7 12.6 4.2 18.3 8.8 12.2 11.2 6.0 12.7 17.6 11.9 21.0 10.3 10.6 16.6 7.8 16.0 16.3 0.0 2.9 0.8 2.3 1.8 7.7 6.4 10.2 4.0 5.7 5.2 7.9 4.9 0.0 3.9 22.7 2.9 9.7 0.0 4.9 3.5 3.3 2.0 0.0 13.9 4.9 6.4 6.4 1.8 4.6 37.3 3.4 1.4 1.7 1.0 10.2 6.5 4.6 3.5 3.5 5.1 14.1 12.9 2.1 16.9 5.3 2.9 6.1 1.9 10.4 2.6 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Basal glandular cells: 55.8;Basal keratinocytes: 59.3;Spermatogonia: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol NA NA Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 6.3 5.3 11.2 4.0 16.6 7.1 8.7 12.7 16.5 10.9 4.9 19.7 2.6 3.7 15.3 7.7 9.3 6.5 4.1 11.0 9.0 6.3 6.2 7.7 7.3 3.6 24.6 8.1 3.7 6.3 20.6 10.4 7.4 17.4 9.6 4.9 2.8 6.0 8.5 10.9 15.9 3.4 14.2 14.8 2.8 3.5 20.7 19.3 1.7 4.2 2.4 4.9 13.4 9.5 0.5 0.8 0.6 1.3 0.1 2.1 0.2 9.5 10.1 2.9 4.0 5.3 4.2 2.7 3.3 3.0 4.3 5.2 6.4 5.8 3.2 3.6 4.2 7.0 12.6 7.2 13.1 7.1 2.3 2.9 1.3 5.8 13.4 6.7 3.3 3.6 3.5 11.3 8.0 18.5 1.6 7.6 3.2 3.9 10.0 5.8 6.5 1.6 2.8 5.8 3.2 3.1 7.9 8.2 6.4 6.4 14.3 7.8 5.1 5.2 10.3 2.9 3.4 4.1 7.4 4.5 8.8 6.5 4.4 9.0 3.3 5.4 3.4 6.3 4.5 3.5 0.1 0.7 0.6 0.8 0.3 2.1 0.1 0.7 1.5 0.8 0.5 0.8 0.8 0.1 0.1 1.3 0.2 1.3 0.2 11.2 16.6 12.7 16.5 9.0 6.3 24.6 8.1 17.4 19.3 6.0 3.0 6.1 55.8 59.3 12.6 9.2 10.2 8.1 7.9 5.2 2.0 11.1 0.0 6.1 3.6 14.6 1.4 0.0 7.2 6.2 5.4 14.2 1.1 25.0 4.2 0.0 4.6 7.4 3.1 8.9 7.2 2.9 6.8 1.0 3.5 4.8 7.6 0.0 4.2 9.1 7.4 19.4 7.1 23.8 60.3 23.2 6.3 1.3 5.2 19.5 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60179094-60422470 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Cell type enhanced" "Detected in all" 11 "Cone photoreceptor cells: 227.8;Rod photoreceptor cells: 128.6;Spermatocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 28.4" "Group enriched" "Detected in many" 10 "dendritic cells: 28.4;granulocytes: 13.5" "Cell line enhanced" "Detected in all" "MCF7: 61.6" HPA044365 Approved Approved "Golgi apparatus,Cytosol" NA NA "Golgi apparatus" Cytosol "HPA044365: AB_2678914" "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 9.5 13.9 17.3 10.8 19.5 20.6 10.9 14.6 20.3 8.0 8.5 18.9 7.9 7.2 8.2 5.4 13.1 7.4 9.1 11.1 14.7 12.2 15.5 19.7 12.5 8.6 18.8 14.3 7.4 8.5 17.3 11.4 9.8 19.2 8.7 8.9 11.6 8.2 9.0 23.0 12.2 7.2 9.8 16.5 12.1 8.1 58.4 18.1 7.3 15.6 7.9 8.5 8.8 8.5 1.4 28.4 13.5 2.1 0.6 1.1 0.9 11.1 12.7 6.8 10.8 17.2 16.2 6.4 9.1 13.8 12.0 15.4 6.6 7.3 6.9 7.7 16.8 19.3 5.9 11.5 12.6 21.2 5.2 5.1 13.8 10.1 7.2 17.1 10.9 12.6 15.1 9.3 16.1 14.9 12.4 13.1 8.3 13.9 5.7 14.8 61.6 11.0 7.7 7.9 10.7 6.1 5.3 17.9 4.1 12.6 8.1 4.8 7.2 7.6 2.2 11.7 12.3 9.4 15.2 11.0 18.2 19.0 11.4 8.5 5.9 11.2 6.5 9.1 8.6 11.8 4.3 2.1 7.2 1.0 1.8 0.7 1.4 0.7 0.8 4.1 1.1 0.5 1.0 13.5 0.6 2.0 28.4 1.1 0.9 17.3 19.5 14.6 20.3 14.7 12.2 18.8 14.3 19.2 18.1 6.0 13.1 7.7 11.6 23.9 16.9 7.6 5.1 6.7 13.6 5.2 227.8 4.3 3.3 9.0 69.1 8.4 6.8 23.3 6.3 5.3 10.4 9.3 11.5 10.6 16.5 12.7 7.9 9.2 33.2 25.6 12.0 27.7 5.0 14.4 4.2 10.3 8.4 9.1 5.3 3.7 128.6 25.8 9.5 100.3 9.1 19.2 4.1 12.9 4.4 7.1 USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Nucleoplasm, Golgi apparatus" "HPA005719: AB_10601708" "unprognostic (2.31e-3)" "unprognostic (2.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (9.19e-3)" "unprognostic (1.88e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" "unprognostic (5.36e-3)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" 30.8 27.1 28.1 18.8 32.1 24.6 28.6 55.3 37.5 21.6 20.4 20.6 18.5 20.2 23.3 23.0 17.8 19.2 21.7 17.0 30.7 30.6 26.0 20.3 21.0 20.7 26.0 25.4 25.3 17.0 28.8 23.4 34.6 38.7 24.6 21.0 21.4 19.5 19.8 16.3 19.4 23.8 19.8 21.4 22.3 19.5 19.9 21.6 27.8 25.1 12.9 20.3 21.0 20.0 15.7 12.2 33.2 18.4 12.3 17.8 10.6 16.1 7.4 25.6 17.7 36.9 32.3 22.0 17.7 16.9 21.6 24.3 9.8 14.0 12.1 16.8 17.2 35.5 12.8 18.6 12.1 26.6 11.1 14.5 42.7 18.1 8.5 23.0 14.5 10.8 23.7 9.5 20.9 15.4 20.9 19.2 11.1 16.6 10.6 16.2 6.2 13.1 14.5 24.7 12.6 14.7 12.6 27.0 8.5 20.4 16.6 21.5 16.6 12.4 16.5 24.7 22.8 9.2 15.8 16.1 20.0 14.2 20.1 16.7 8.7 11.0 11.8 15.1 17.2 10.1 33.2 15.4 20.0 15.1 15.0 15.3 13.4 14.7 15.2 11.5 15.7 17.8 15.6 20.9 12.3 18.4 12.2 13.2 10.6 28.1 32.1 55.3 37.5 30.7 30.6 26.0 25.4 38.7 21.6 41.7 36.3 21.6 16.5 15.2 50.9 31.5 20.4 36.1 25.0 33.2 55.0 21.0 8.3 16.9 2.8 26.4 26.8 0.0 13.4 15.9 21.2 23.9 22.0 18.1 16.5 58.8 34.1 28.8 33.6 3.6 33.1 22.3 21.9 19.8 26.0 34.5 15.7 28.6 30.1 19.2 40.3 19.4 17.5 36.1 26.3 14.3 10.0 27.5 22.9 20.0 USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61470769 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025815, HPA070764" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA025815: AB_1858681, HPA070764: AB_2686308" "unprognostic (4.04e-2)" "unprognostic (8.21e-3)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (8.91e-2)" "unprognostic (4.62e-2)" "unprognostic (9.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (7.01e-2)" 17.2 19.6 31.8 37.2 25.6 24.8 28.3 77.1 35.5 22.5 22.7 14.4 31.1 11.4 22.2 44.5 18.6 17.5 20.0 16.9 30.5 24.0 20.5 21.5 29.7 34.2 22.0 21.2 24.7 17.2 33.5 40.3 13.4 22.0 22.7 21.5 21.2 16.9 45.2 27.0 31.6 21.0 22.7 20.8 24.8 19.3 26.4 25.3 21.7 23.2 13.9 33.5 19.1 16.7 6.0 5.8 3.4 4.6 5.2 7.5 2.3 16.8 12.1 15.7 16.3 29.9 20.1 13.2 10.4 14.7 9.3 8.9 16.9 6.5 40.0 11.1 22.4 9.9 9.3 12.4 13.7 17.4 14.3 9.8 24.2 11.7 27.2 25.2 17.9 15.4 21.9 17.8 17.0 25.4 22.8 19.6 11.4 16.5 13.0 20.7 15.8 11.8 26.1 10.6 17.2 9.6 12.7 19.2 10.7 27.5 20.7 13.0 13.9 16.4 12.2 17.9 21.0 6.4 13.0 17.5 14.8 19.7 8.7 13.6 15.1 7.4 42.0 13.9 16.7 12.6 3.4 2.0 2.8 7.5 2.2 6.7 5.1 5.1 5.5 1.8 6.0 5.8 7.5 3.4 5.2 4.6 5.8 4.5 2.3 31.8 25.6 77.1 35.5 30.5 24.0 22.0 21.2 22.0 25.3 59.6 60.6 35.3 50.1 54.3 132.9 41.8 56.0 33.5 59.1 31.4 235.6 26.6 8.3 35.4 108.3 51.2 38.6 0.0 29.1 19.8 45.2 63.1 31.2 36.3 19.7 101.7 46.7 23.4 40.3 105.2 52.6 41.4 38.8 30.7 32.2 62.5 38.7 38.4 62.9 18.3 185.3 25.8 46.7 97.9 106.7 53.6 44.6 40.8 31.2 57.6 USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78214711 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 32.4" "Group enriched" "Detected in many" 4 "Early spermatids: 20.7;Late spermatids: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "eosinophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" Nucleoplasm "HPA055213: AB_2682740, HPA058592: AB_2683766" "unprognostic (6.69e-2)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.57e-2)" "unprognostic (3.84e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (1.29e-3)" "unprognostic (2.93e-1)" "unprognostic (1.31e-1)" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" 4.9 17.1 5.1 5.4 9.3 3.8 5.2 10.4 15.0 6.4 5.8 8.0 6.3 5.5 6.8 5.4 5.6 5.4 5.6 8.7 6.1 6.7 5.0 13.8 5.6 4.8 6.7 8.8 6.6 6.4 32.4 12.0 7.1 15.0 5.0 3.4 7.7 4.0 5.6 5.6 3.2 5.3 7.8 4.5 4.6 3.9 5.3 4.0 1.9 7.7 2.9 4.1 5.2 6.6 0.0 0.1 3.4 0.6 0.1 0.3 0.2 2.1 3.3 5.7 6.0 9.7 9.0 3.9 4.9 5.8 5.8 4.1 8.3 4.6 1.7 5.1 9.2 6.2 5.7 3.8 7.6 3.4 12.2 2.0 2.8 8.6 4.8 7.6 1.8 8.3 7.6 5.1 12.1 3.5 11.5 7.1 6.2 3.9 4.2 4.5 1.9 4.6 7.2 1.7 6.0 5.3 2.8 5.3 2.0 4.6 3.9 2.8 5.4 3.8 5.0 1.8 8.5 4.2 1.5 8.6 10.7 6.1 12.6 2.6 5.7 1.8 2.6 3.2 1.9 6.2 0.0 0.2 3.4 0.1 0.6 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.2 5.1 9.3 10.4 15.0 6.1 6.7 6.7 8.8 15.0 4.0 0.0 2.6 0.0 0.1 0.7 0.7 1.8 0.0 0.0 0.0 0.0 5.9 0.6 0.0 0.8 20.7 1.5 0.8 0.0 1.7 1.3 2.0 0.2 0.0 3.0 1.3 0.0 0.0 2.5 0.8 31.6 1.4 0.9 1.7 3.6 0.6 0.5 1.8 0.0 2.8 0.8 0.5 6.5 0.9 0.9 1.6 0.9 0.2 3.9 0.7 0.1 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: AB_2681974" "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 26.3 23.4 12.9 21.3 16.0 36.5 28.1 28.3 17.4 17.2 16.4 25.4 19.2 12.3 25.1 22.2 14.6 18.0 21.9 17.4 10.4 11.2 15.9 16.4 20.0 17.2 17.5 16.0 41.3 33.6 19.6 30.0 23.4 14.6 21.0 15.1 20.4 21.8 45.5 19.5 29.3 15.1 25.2 14.5 18.2 17.3 20.8 13.7 12.8 19.3 11.2 22.2 24.6 18.1 6.7 12.4 8.9 5.3 5.6 8.8 2.5 16.0 19.4 5.7 10.6 12.3 13.7 11.0 13.2 13.4 12.7 8.6 18.8 8.1 20.5 6.7 11.7 13.8 11.8 13.4 9.8 22.8 4.9 20.3 18.7 28.3 19.6 12.7 20.5 10.3 11.9 16.3 18.1 40.6 9.8 11.0 9.3 14.9 21.7 10.4 12.3 18.6 20.8 8.8 12.0 15.6 14.4 12.6 13.8 8.0 17.0 16.9 10.3 9.5 44.3 24.0 13.0 11.4 13.1 9.3 30.1 14.0 17.5 23.3 16.1 6.3 25.3 11.8 16.0 9.4 8.9 3.9 3.1 7.6 5.3 8.8 6.4 7.2 6.4 2.3 6.7 8.0 7.7 5.7 5.6 3.3 12.4 4.8 2.5 12.9 16.0 28.3 17.4 10.4 11.2 17.5 16.0 14.6 13.7 11.9 41.5 16.3 21.0 45.9 31.4 13.5 15.3 12.0 26.1 14.0 31.4 6.9 5.0 8.7 12.1 20.4 6.8 0.0 8.3 8.9 25.9 22.8 19.7 12.4 34.2 25.4 17.7 12.3 20.6 6.1 10.9 34.8 28.7 10.8 13.6 17.3 10.7 8.6 11.7 4.1 32.5 6.5 22.7 14.2 10.6 37.9 10.8 30.5 14.0 20.4 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 117.3;Late spermatids: 116.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 10.4 8.4 9.2 9.7 10.5 19.2 9.0 16.2 10.0 8.3 6.6 10.4 8.0 5.8 9.6 15.8 8.2 7.8 7.0 6.9 7.4 5.5 6.1 7.4 8.1 10.5 8.7 7.8 15.3 6.9 10.7 17.1 8.5 8.7 7.3 7.0 7.4 9.7 9.6 11.1 9.9 7.2 8.1 10.2 7.0 6.6 22.2 10.5 13.4 9.8 5.4 9.4 10.5 9.1 7.4 6.1 7.4 4.8 5.9 9.0 2.5 7.4 5.4 11.5 8.8 3.0 3.7 9.8 5.7 4.1 9.9 11.2 10.2 5.9 6.8 6.2 4.4 7.6 7.1 12.5 6.3 10.9 9.2 6.6 18.3 11.0 6.7 3.4 11.9 9.2 2.0 3.8 10.4 7.5 3.6 4.2 11.9 13.2 13.1 6.2 5.5 15.3 8.2 9.8 4.8 4.7 12.4 17.2 6.2 3.4 8.8 12.6 6.8 9.1 4.5 5.7 11.5 5.2 8.4 5.4 11.2 9.8 6.2 7.4 8.9 7.9 13.9 6.0 8.8 7.6 6.5 4.2 7.4 7.0 4.8 7.3 5.4 5.8 5.9 4.4 7.4 9.0 5.7 3.5 5.9 4.4 6.1 7.3 2.5 9.2 10.5 16.2 10.0 7.4 5.5 8.7 7.8 8.7 10.5 0.0 8.3 11.5 5.5 17.3 16.4 3.3 2.5 10.7 10.3 7.0 25.5 6.1 0.0 4.6 117.3 9.0 5.1 0.0 2.0 5.4 9.3 10.2 4.7 10.2 6.5 14.3 9.9 11.6 8.1 116.2 9.2 13.7 20.3 5.4 8.1 9.9 4.6 6.8 9.2 3.6 21.1 6.5 10.3 40.0 12.8 18.1 6.1 17.9 7.0 5.8 USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 45.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA Nucleoplasm "Centrosome, Cytosol" "HPA036990: AB_2675419, HPA047948: AB_2680220" "unprognostic (5.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.04e-3)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.49e-2)" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (8.03e-2)" "unprognostic (7.72e-3)" "prognostic favorable (1.20e-4)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" 7.7 7.8 6.6 6.6 6.5 19.1 8.3 7.4 7.8 7.9 12.1 8.6 8.8 8.8 8.3 7.1 8.6 7.1 7.6 12.5 6.6 5.3 9.3 15.2 12.7 11.1 10.3 5.1 6.3 8.8 10.0 6.2 11.4 5.9 6.6 6.6 7.1 7.2 7.0 45.3 8.9 13.2 6.5 10.8 10.6 7.4 7.5 8.2 22.6 8.6 10.2 8.4 7.8 8.8 6.3 8.1 12.5 5.7 12.3 9.9 5.0 4.8 4.5 4.0 6.9 5.3 5.3 3.0 7.7 7.5 7.2 6.1 13.1 7.2 6.0 5.5 6.5 4.6 3.8 9.5 7.7 5.9 14.6 6.1 5.5 5.4 2.8 7.3 11.1 5.5 6.4 7.1 7.3 5.9 5.1 7.1 6.9 11.9 18.9 4.7 7.7 14.5 2.1 3.6 9.8 8.9 9.5 6.0 5.7 4.6 5.6 8.2 7.4 6.0 10.5 6.7 3.1 6.4 4.2 8.4 6.6 5.4 5.7 8.0 21.1 35.7 10.9 6.7 8.5 5.5 12.5 5.4 11.7 7.5 5.7 9.6 6.3 6.6 6.5 8.1 5.7 6.7 5.7 5.4 12.3 5.7 3.5 9.9 5.0 6.6 6.5 7.4 7.7 6.6 5.3 10.3 5.1 5.9 8.2 20.8 13.7 10.5 16.5 47.6 7.5 15.1 7.6 13.4 14.8 0.0 11.8 10.9 1.7 7.5 27.8 12.0 18.4 0.0 6.6 5.8 9.7 16.1 3.5 32.7 9.2 7.9 29.4 17.8 14.5 15.4 6.4 12.2 11.8 1.8 19.9 13.6 8.5 11.5 8.9 14.2 8.2 12.9 15.1 9.5 5.1 51.7 22.3 13.4 14.5 38.1 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277831-49340712 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 100.2;Late spermatids: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favorable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favorable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 22.1 18.4 21.4 22.4 29.3 41.4 23.1 30.3 32.5 20.7 20.1 26.8 16.9 16.1 23.6 20.9 23.5 19.3 17.5 22.8 22.2 18.0 20.2 18.5 25.7 25.5 20.2 17.5 23.6 17.1 23.6 19.7 22.1 24.3 20.9 21.9 23.6 19.1 21.3 25.7 27.6 19.4 25.9 20.4 30.6 17.7 25.0 19.7 36.8 21.2 14.1 42.4 22.1 22.0 17.0 24.1 59.4 27.3 21.5 18.6 22.2 6.4 7.4 10.2 13.6 19.0 20.4 6.9 17.5 15.6 22.7 20.5 7.8 16.2 12.4 7.0 25.5 13.1 8.7 13.6 24.8 21.2 19.1 4.0 27.5 14.7 8.7 27.9 14.5 15.9 20.9 10.9 24.9 20.5 16.5 26.2 14.1 9.6 19.7 21.0 10.9 17.1 24.6 8.7 8.0 12.9 7.1 6.4 10.8 17.8 13.3 8.5 11.4 12.7 9.0 6.5 10.7 6.2 23.3 23.2 15.3 8.3 19.1 10.2 15.8 7.6 18.1 13.7 23.0 17.5 18.0 27.3 30.0 16.9 22.1 18.6 17.0 17.6 16.9 24.1 14.1 17.1 15.0 59.4 21.5 24.4 9.6 18.6 22.2 21.4 29.3 30.3 32.5 22.2 18.0 20.2 17.5 24.3 19.7 38.7 21.4 18.1 15.0 16.7 16.6 15.3 15.3 33.5 25.0 19.2 19.6 18.9 18.3 14.2 100.2 17.9 11.6 0.0 11.9 12.1 12.3 13.1 32.4 12.1 21.7 11.1 10.3 16.0 38.8 90.2 14.4 25.3 15.1 30.7 11.4 12.0 14.6 5.8 18.0 10.5 21.5 12.9 14.7 18.5 13.6 16.2 20.3 24.9 11.9 11.8 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA Vesicles "Focal adhesion sites" "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 12.5 20.5 11.0 8.2 17.7 3.5 16.1 8.2 13.5 12.4 12.1 26.1 22.5 11.6 16.2 28.1 13.9 13.4 13.2 10.8 11.3 8.5 16.9 15.7 13.9 7.6 22.1 10.1 19.6 17.2 22.8 24.3 16.3 16.5 16.1 11.2 16.4 13.9 19.7 13.6 21.7 15.2 17.1 20.1 11.4 16.3 23.3 18.9 9.8 21.2 9.4 12.0 18.0 11.8 1.9 5.0 0.4 2.8 1.4 2.2 1.4 9.5 11.1 10.2 6.9 15.0 14.1 9.0 9.4 7.3 8.8 9.6 7.9 11.4 0.2 2.8 15.1 22.6 17.0 7.8 16.7 12.6 0.0 5.1 7.5 9.2 13.3 13.1 3.1 5.1 13.4 12.1 12.9 18.2 15.4 10.1 4.6 12.1 1.8 12.3 7.7 3.4 4.7 4.5 9.9 9.0 0.0 21.2 4.4 10.4 15.4 5.6 6.1 7.5 7.8 9.7 8.0 8.8 7.1 9.9 12.2 7.6 5.1 11.4 3.4 2.6 0.4 15.9 5.7 10.6 0.0 2.7 0.0 1.3 2.8 0.6 1.3 1.5 1.3 4.0 1.9 1.9 2.2 0.4 1.4 2.3 5.0 2.0 1.4 11.0 17.7 8.2 13.5 11.3 8.5 22.1 10.1 16.5 18.9 29.8 31.5 3.7 9.6 6.5 18.6 8.9 10.2 24.1 23.9 15.7 23.6 17.1 6.6 7.9 6.7 7.1 10.9 0.0 10.6 8.8 7.4 11.3 9.2 20.9 7.0 22.3 14.5 12.3 10.4 7.8 6.4 6.7 3.3 5.4 9.1 13.0 9.7 8.6 7.8 11.6 20.8 12.9 8.2 31.2 14.9 9.3 13.2 4.4 11.2 7.1 USP41 ENSG00000161133 "Ubiquitin specific peptidase 41" Q3LFD5 22 20350578-20390758 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 1.6;RH-30: 4.2;RT4: 1.7;SCLC-21H: 4.9;SK-BR-3: 1.8;U-937: 1.5" NA NA "unprognostic (4.01e-6)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (4.63e-3)" "unprognostic (7.44e-2)" "unprognostic (1.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (9.91e-5)" "unprognostic (3.43e-2)" "unprognostic (3.51e-2)" "unprognostic (2.54e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.63e-1)" 0.7 0.3 0.4 0.0 0.6 1.0 0.6 0.0 1.8 0.3 0.3 1.6 0.2 0.0 0.2 0.2 0.0 0.1 0.4 0.4 0.1 0.9 1.3 0.1 0.2 0.1 0.2 0.0 0.4 0.1 0.4 0.2 0.5 0.0 0.7 0.1 0.3 0.0 0.3 0.3 2.0 0.3 0.4 0.3 0.3 0.1 0.4 1.2 0.3 0.4 0.4 0.5 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.9 0.0 1.6 0.0 0.4 0.0 4.2 0.0 0.0 1.7 4.9 0.2 0.0 1.8 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.8 1.2 1.5 0.3 0.0 0.0 0.3 0.2 0.2 0.4 0.4 0.1 0.5 0.1 0.2 0.0 0.2 0.0 0.4 0.4 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP42 FLJ12697 ENSG00000106346 "Ubiquitin specific peptidase 42" Q9H9J4 7 6104884-6161564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 70.7;Spermatocytes: 67.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064800 Approved Nucleoplasm NA NA Nucleoplasm "HPA064800: AB_2685355" "unprognostic (1.48e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (2.82e-1)" "unprognostic (6.21e-3)" "unprognostic (2.47e-2)" "unprognostic (3.17e-3)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.66e-1)" 6.7 5.6 5.7 5.7 9.5 19.8 7.2 14.1 10.6 8.5 7.4 10.4 5.5 8.1 14.1 7.0 6.9 8.1 6.5 5.4 5.8 6.0 7.4 7.1 7.3 6.5 6.7 4.9 10.6 11.7 10.5 10.9 8.2 6.2 7.4 6.5 8.9 6.6 6.3 7.4 9.2 9.2 8.7 9.9 7.8 6.7 25.2 8.1 14.3 7.7 6.2 8.3 7.6 6.9 1.9 2.2 3.3 2.4 1.9 4.3 0.8 8.4 6.3 11.4 11.1 6.6 5.0 7.8 4.6 5.9 5.4 5.4 4.4 4.5 10.1 3.0 5.7 8.0 7.9 9.5 5.0 5.9 2.4 7.4 4.6 5.4 4.5 5.6 10.8 5.3 5.9 6.0 5.8 7.5 5.0 6.6 8.5 17.8 6.8 3.6 7.5 6.5 12.1 12.9 4.4 4.8 12.4 8.9 6.9 5.1 4.5 8.8 15.5 5.8 12.2 3.6 10.9 5.6 5.6 5.5 4.9 18.1 6.1 5.4 6.1 5.1 8.8 4.1 6.6 9.5 2.3 1.1 3.3 2.1 2.4 3.0 1.9 2.6 1.3 1.1 1.1 1.7 4.3 1.4 1.9 1.2 2.2 1.8 0.8 5.7 9.5 14.1 10.6 5.8 6.0 6.7 4.9 6.2 8.1 11.9 6.5 11.5 16.3 35.9 18.1 6.9 0.0 10.7 6.8 1.8 21.6 7.3 0.0 9.4 70.7 12.2 12.5 0.0 8.9 6.5 8.5 16.7 9.2 7.8 7.2 20.6 10.3 14.7 7.0 32.5 13.3 11.5 10.1 6.4 14.6 11.3 10.2 7.0 12.0 4.2 17.9 12.9 11.3 67.4 32.6 36.3 22.4 12.1 11.3 13.5 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729691 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell type enhanced" "Detected in many" 11 "Syncytiotrophoblasts: 61.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 12.4;SK-BR-3: 8.6;T-47d: 10.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762" Uncertain NA NA "HPA023389: AB_1858691, HPA027762: AB_10603001" "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.2 0.2 4.2 1.2 3.4 0.9 3.0 0.7 6.0 4.9 10.0 0.6 15.7 6.2 2.9 1.7 6.7 6.3 5.1 0.2 4.1 3.8 3.7 8.7 3.4 0.2 1.7 3.1 1.0 7.7 1.7 3.7 61.6 0.7 10.8 5.0 0.3 11.3 12.4 0.2 2.4 12.5 0.3 1.0 0.2 2.6 2.9 0.2 0.4 1.7 4.2 2.7 1.3 2.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 5.7 1.5 0.0 0.6 0.0 0.0 12.4 0.1 0.2 0.7 1.7 2.8 4.7 0.0 1.9 0.2 2.7 7.0 0.6 5.5 0.7 3.6 1.9 0.3 3.0 1.0 0.1 0.5 0.0 0.0 7.2 0.3 3.0 0.3 0.0 0.8 0.0 0.0 0.0 2.7 0.9 4.7 0.7 4.9 0.3 3.7 0.0 0.8 4.4 3.1 0.8 0.0 2.5 8.6 1.0 4.1 10.4 1.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 4.2 3.4 0.7 6.0 4.1 3.8 1.7 3.1 0.7 0.2 3.0 1.9 0.0 7.2 4.1 0.0 0.5 7.6 21.4 7.9 10.4 5.9 16.6 1.7 3.9 1.1 0.0 9.0 0.0 4.0 19.6 0.6 9.5 0.0 12.4 2.4 0.0 2.4 0.0 1.6 0.8 0.0 0.0 5.0 0.0 7.8 8.1 8.5 2.9 0.0 1.3 1.3 0.0 0.3 1.1 0.2 2.9 61.2 0.0 9.0 10.0 USP44 FLJ14528 ENSG00000136014 "Ubiquitin specific peptidase 44" Q9H0E7 12 95516560-95551490 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.8" "Cell type enriched" "Detected in many" 4 "Early spermatids: 343.6" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Region enriched" "Detected in many" 5 "cerebellum: 10.9" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.6" "Group enriched" "Detected in many" 39 "B-cells: 5.6;T-cells: 8.6" "Cell line enhanced" "Detected in some" "HEL: 10.0;JURKAT: 22.6;NTERA-2: 54.2" "Low region specificity" "Detected in some" HPA026543 Approved "Nucleoli fibrillar center,Microtubules" NA NA "Nucleoli fibrillar center, Microtubules" "HPA026543: AB_1858692" "unprognostic (2.12e-2)" "unprognostic (1.14e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (1.83e-4)" "unprognostic (7.18e-4)" "unprognostic (5.55e-2)" "unprognostic (1.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.73e-2)" "unprognostic (6.88e-2)" "unprognostic (2.97e-2)" "unprognostic (8.12e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.41e-2)" "unprognostic (7.07e-2)" 1.3 1.0 0.7 1.2 1.3 0.5 1.4 10.9 2.1 1.7 1.7 1.7 1.4 0.5 3.0 1.0 0.9 1.6 1.1 1.0 0.7 0.6 1.9 0.2 4.7 1.9 1.3 1.2 1.6 3.6 4.8 4.0 0.3 1.8 1.7 0.6 2.3 1.8 2.6 0.4 0.6 1.3 1.2 0.6 1.9 1.0 26.8 1.2 0.8 1.7 0.0 1.6 1.1 2.3 5.6 0.1 0.1 0.0 0.1 8.6 1.3 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.4 1.3 0.5 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.2 10.0 0.0 0.0 2.3 4.0 0.2 0.0 0.0 0.3 0.0 0.2 0.2 22.6 1.5 0.0 0.0 0.0 5.1 0.0 54.2 0.0 0.0 0.0 0.0 0.0 0.9 0.3 3.5 2.3 0.0 0.0 0.0 5.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 3.4 5.6 2.3 2.0 0.0 4.4 8.6 5.5 0.1 0.1 0.0 0.1 0.3 1.3 0.7 1.3 10.9 2.1 0.7 0.6 1.3 1.2 1.8 1.2 11.9 19.9 0.0 2.9 0.9 6.2 1.2 0.0 0.0 6.8 7.0 5.9 2.1 0.0 3.9 343.6 2.3 0.0 0.0 2.7 0.3 1.0 2.7 0.0 0.0 0.1 0.0 0.0 1.3 0.3 78.5 5.2 0.4 3.3 1.0 0.0 3.4 1.3 0.0 3.2 1.1 8.6 6.5 3.1 10.0 5.2 0.6 0.9 1.7 0.0 1.6 USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432379-99521728 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604" Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA029602: AB_10600418, HPA029604: AB_10602283" "unprognostic (7.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (2.95e-3)" "unprognostic (1.10e-1)" "unprognostic (3.43e-3)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.43e-1)" "unprognostic (6.91e-2)" 9.8 9.1 8.5 10.2 12.2 7.2 9.0 28.4 11.6 9.0 9.7 8.6 8.9 13.7 15.7 9.6 10.0 8.1 11.9 11.5 7.7 8.5 12.2 9.0 7.1 12.7 9.8 8.0 10.7 9.6 10.2 21.7 9.6 15.0 9.9 13.1 7.9 9.8 8.4 14.6 11.8 12.4 10.8 10.6 9.9 8.9 5.7 9.4 7.1 10.7 10.4 9.5 8.8 15.0 8.6 5.1 3.7 2.5 2.6 6.2 1.4 4.2 3.0 6.0 8.5 11.2 10.6 6.4 7.4 8.3 7.7 11.1 6.3 4.8 11.3 5.5 7.4 9.1 5.8 9.2 7.3 10.7 8.9 8.8 11.0 6.0 4.9 8.6 10.2 6.3 11.3 5.9 6.9 11.9 8.2 11.4 10.3 26.5 11.3 7.3 3.9 3.2 9.8 9.7 6.6 6.5 4.8 4.5 6.3 10.8 5.0 8.5 7.0 5.3 6.9 5.4 7.9 3.7 5.0 11.5 4.2 5.4 6.2 11.2 4.8 4.4 20.7 7.3 9.7 7.5 3.7 2.0 0.6 4.9 1.3 6.2 7.4 4.2 5.6 3.5 8.6 3.0 2.9 0.5 2.6 2.5 5.1 3.5 1.4 8.5 12.2 28.4 11.6 7.7 8.5 9.8 8.0 15.0 9.4 3.0 4.3 4.4 6.8 2.1 7.9 7.1 7.6 12.0 3.4 3.5 17.7 5.3 5.0 3.9 10.8 5.3 5.8 0.0 2.3 5.9 3.8 5.6 2.3 3.8 3.5 9.5 2.4 8.0 4.1 5.9 12.0 3.9 3.3 13.6 2.3 5.6 4.3 2.9 8.1 13.4 7.6 0.0 6.2 1.8 5.5 2.5 6.2 5.1 6.0 6.5 USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590972-52659335 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Bipolar cells: 123.5;Early spermatids: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved "Nucleoli,Nucleoli rim" NA NA "Nucleoli, Nucleoli rim" "CAB076369: AB_2665642, CAB076370: AB_2665643, HPA007288: AB_1080531" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-3)" "unprognostic (1.59e-1)" "unprognostic (2.45e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" 4.7 9.5 26.0 3.5 20.9 2.8 7.0 23.7 29.4 8.9 4.2 12.8 5.2 4.8 7.2 6.2 12.4 7.8 5.8 28.9 21.9 19.0 10.8 3.1 4.4 3.7 19.1 13.9 12.3 5.6 12.2 5.3 10.6 12.7 7.7 4.6 5.3 8.0 7.8 13.7 8.0 4.5 5.5 18.9 3.5 6.3 12.2 15.0 1.0 10.0 4.3 5.8 7.3 5.7 1.4 4.4 2.0 1.4 1.2 3.9 1.0 5.4 3.8 12.5 9.2 13.6 17.1 13.8 8.9 7.2 6.6 5.6 7.7 4.2 3.6 10.5 8.8 9.3 3.2 21.7 10.3 12.1 3.1 7.6 5.6 3.7 8.6 13.6 7.3 6.5 14.5 9.7 6.8 6.4 12.9 9.8 5.1 5.5 5.1 13.9 4.9 3.1 3.9 9.2 6.0 4.7 8.0 9.1 0.7 14.2 10.0 7.5 9.0 4.3 14.9 8.5 12.5 5.4 5.5 9.0 6.5 14.2 7.6 13.3 5.2 2.4 2.9 10.0 4.5 8.0 2.0 1.4 0.3 2.3 1.2 1.7 1.4 3.9 2.0 2.8 1.2 0.9 0.8 0.3 1.2 0.9 4.4 1.2 1.0 26.0 20.9 23.7 24.3 21.9 19.0 19.1 13.9 12.7 15.0 6.0 4.5 1.9 9.8 4.7 123.5 42.3 12.7 24.1 11.4 14.0 3.9 10.5 18.3 10.3 151.7 8.4 3.8 0.0 10.5 10.9 10.3 17.3 0.0 5.7 5.0 33.4 4.1 7.4 7.6 24.3 26.7 4.4 8.5 14.4 5.6 21.3 9.7 7.6 33.9 12.6 7.9 6.5 8.3 3.0 11.5 7.2 6.4 4.4 6.0 15.9 USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11959323 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported Approved "Vesicles,Intermediate filaments" NA NA "Intermediate filaments" Vesicles "HPA029286: AB_10599852, HPA029289: AB_10601675" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.27e-2)" "unprognostic (7.39e-2)" "unprognostic (1.54e-2)" "unprognostic (7.05e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (9.96e-3)" "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" 16.6 17.0 17.9 18.5 20.9 20.3 16.9 25.7 19.0 16.4 18.1 16.2 21.3 11.6 18.0 15.0 18.7 13.7 13.5 25.5 18.1 13.4 14.6 25.1 16.6 13.4 21.9 12.9 16.9 19.6 38.8 31.8 23.7 19.3 18.0 14.2 10.2 15.1 19.2 58.1 18.4 15.1 21.3 19.5 13.3 18.1 16.8 23.9 27.9 16.8 12.4 15.2 21.3 19.4 9.7 10.1 14.0 13.2 22.8 19.3 9.7 21.4 13.1 23.5 11.1 17.0 18.8 10.8 24.7 18.7 16.3 18.5 12.9 19.1 24.3 11.8 22.9 19.4 14.7 18.1 12.4 25.2 23.6 15.3 14.6 24.2 9.0 15.1 18.9 20.5 17.4 17.1 10.7 23.8 18.6 18.1 17.2 29.1 21.0 19.9 8.5 17.0 8.4 6.3 21.3 10.6 17.6 24.8 7.5 17.6 24.9 8.2 16.7 22.1 15.4 13.7 15.1 12.3 13.9 20.0 23.1 14.1 19.6 15.0 6.6 15.2 23.0 15.9 11.7 16.6 13.3 7.7 14.0 15.2 9.5 19.3 9.7 13.8 14.7 10.1 8.6 17.9 15.3 3.6 22.8 13.2 6.1 9.9 9.7 17.9 20.9 25.7 19.0 18.1 13.4 21.9 12.9 19.3 23.9 65.5 50.8 26.5 58.2 63.1 66.5 188.1 30.6 62.9 67.1 22.7 45.2 55.8 21.6 33.6 26.3 35.8 25.1 23.3 33.7 29.2 48.3 58.2 51.0 50.0 24.2 60.4 56.9 30.1 18.5 22.9 40.9 32.0 23.6 27.9 30.5 80.7 36.7 31.6 47.0 17.9 50.6 51.8 47.2 72.0 59.0 76.9 105.2 47.3 32.2 47.7 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 20.1 38.8 18.6 28.9 30.9 30.9 22.1 48.2 27.5 19.9 18.4 25.6 15.4 17.6 21.3 17.6 19.0 17.4 20.5 17.8 16.9 15.8 15.5 18.3 18.3 26.2 26.6 22.5 27.0 19.8 24.6 35.4 23.1 26.8 21.6 22.0 22.1 24.5 16.3 17.0 23.9 22.2 22.2 19.7 29.1 26.2 15.8 23.6 25.8 23.9 14.0 29.0 19.8 21.0 13.7 10.5 33.7 9.6 5.6 11.2 5.6 14.9 7.1 16.8 12.1 14.6 18.0 16.6 18.8 12.8 12.7 16.8 6.5 15.3 16.8 12.7 17.0 9.9 13.8 20.6 15.2 19.3 16.3 14.1 35.9 26.5 11.8 13.0 18.0 19.2 14.6 13.1 12.8 14.3 17.4 37.2 12.8 28.2 47.5 15.5 7.4 14.9 23.4 10.5 15.3 12.8 21.0 16.9 19.6 14.5 12.6 20.5 12.8 17.7 16.3 42.5 23.5 8.3 21.8 26.4 13.7 11.2 16.7 10.9 38.2 27.1 16.7 13.2 22.3 20.0 33.7 9.6 16.7 6.4 4.6 7.6 13.7 9.5 9.5 10.5 12.8 11.2 7.0 8.9 5.6 5.0 7.7 10.1 5.6 18.6 30.9 48.2 27.5 16.9 15.8 26.6 22.5 26.8 23.6 50.6 38.5 34.3 22.6 19.7 74.8 58.2 22.9 32.1 20.5 19.2 58.9 51.8 21.6 25.0 51.8 24.5 18.7 70.0 17.5 50.1 30.9 20.6 47.5 21.2 26.0 47.7 20.8 28.3 22.2 33.0 32.2 24.7 55.6 47.7 26.9 29.1 20.0 17.5 48.4 16.5 69.2 32.3 25.0 42.9 48.2 22.5 27.2 35.5 30.2 17.1 USP49 MGC20741 ENSG00000164663 "Ubiquitin specific peptidase 49" Q70CQ1 6 41789896-41895361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Bipolar cells: 21.6;Cone photoreceptor cells: 41.2;Erythroid cells: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Cell line enhanced" "Detected in many" "REH: 23.7;U-698: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030254, HPA030255" Uncertain NA NA "HPA030254: AB_10600198, HPA030255: AB_10601218" "unprognostic (1.71e-1)" "unprognostic (4.86e-3)" "unprognostic (1.93e-1)" "unprognostic (2.57e-4)" "unprognostic (4.46e-2)" "unprognostic (2.84e-4)" "unprognostic (7.17e-3)" "unprognostic (5.06e-2)" "unprognostic (1.19e-2)" "unprognostic (3.22e-1)" "unprognostic (5.59e-3)" "unprognostic (8.28e-2)" "unprognostic (1.26e-5)" "unprognostic (5.39e-2)" "unprognostic (4.58e-2)" "unprognostic (4.37e-3)" "unprognostic (3.24e-3)" 2.4 2.4 7.6 3.5 6.0 7.3 2.7 12.7 9.3 2.3 1.9 2.0 4.3 2.2 4.0 2.3 1.8 2.2 2.1 3.5 7.6 4.2 1.6 1.7 2.4 3.7 3.0 5.8 4.0 3.2 2.6 4.8 1.8 4.2 2.4 2.1 3.7 2.7 2.4 3.8 4.1 2.2 3.2 3.2 3.5 2.2 7.4 3.2 7.3 7.7 0.6 3.4 2.8 2.0 1.2 0.7 8.5 1.8 0.8 0.9 0.4 3.0 0.9 12.5 6.1 1.5 1.7 5.1 1.2 1.1 1.8 2.3 3.9 0.7 12.5 1.3 1.5 2.6 1.3 7.7 1.2 2.8 3.1 5.7 4.5 4.7 1.3 1.1 3.5 2.7 1.7 0.9 2.6 1.7 1.7 1.1 13.0 9.3 3.5 1.4 1.8 13.3 5.3 3.4 3.2 1.2 23.7 6.0 2.7 0.7 2.1 8.4 3.4 1.6 0.6 0.7 3.1 1.9 3.2 3.2 4.3 4.3 1.4 1.6 6.5 5.6 33.7 0.5 3.6 0.8 8.5 1.3 1.4 0.8 1.5 0.4 1.2 0.4 0.8 0.5 0.9 0.9 0.7 2.4 0.8 1.8 0.7 0.4 0.4 7.6 6.0 12.7 9.3 7.6 4.2 3.0 5.8 4.2 3.2 0.0 11.9 1.5 2.8 4.4 21.6 3.4 5.1 1.4 6.8 5.2 41.2 2.3 1.7 1.5 6.4 2.4 1.6 23.3 1.7 1.3 3.6 3.3 1.1 1.5 1.8 14.3 0.0 1.3 4.1 6.3 3.4 3.6 3.3 1.0 1.4 3.1 1.8 1.7 5.6 1.0 11.9 6.5 2.5 8.9 15.8 5.5 4.8 2.2 1.7 3.9 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852128-6866632 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol NA NA 820000 "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 18.6 28.7 23.1 17.8 32.6 13.6 12.9 24.6 50.9 15.9 21.5 26.8 13.8 17.6 22.3 12.8 27.7 19.1 14.7 22.4 23.9 28.6 14.9 24.8 14.4 18.6 23.6 33.2 14.4 13.2 29.7 19.6 21.7 36.8 19.5 16.1 11.6 14.1 22.7 41.2 33.5 18.1 25.3 23.6 14.1 15.9 30.9 18.7 22.8 19.2 20.4 19.9 21.3 16.0 10.8 18.6 5.3 16.6 10.8 17.1 16.6 25.6 40.1 27.0 30.5 18.4 17.0 34.5 27.9 21.4 33.4 24.4 37.9 25.5 31.0 14.7 29.0 26.5 22.7 29.6 27.7 21.4 58.2 25.1 28.4 32.3 20.6 14.3 25.6 30.0 17.1 16.1 28.9 20.0 22.4 28.5 12.5 24.4 12.5 27.5 28.1 38.5 12.8 52.6 26.2 17.0 30.3 35.2 21.5 19.1 25.0 14.9 30.1 19.0 29.0 12.1 35.1 11.6 21.1 27.6 28.3 34.3 21.5 34.7 15.0 34.6 47.3 31.5 16.4 27.5 2.3 12.3 5.3 17.1 16.6 16.1 10.8 15.2 14.4 18.6 10.0 14.6 14.8 0.9 10.8 14.7 13.6 12.9 16.6 23.1 32.6 24.6 50.9 23.9 28.6 23.6 33.2 36.8 18.7 8.9 12.5 13.0 9.5 10.3 18.1 8.1 17.8 4.0 5.7 21.0 56.9 38.0 10.0 25.9 8.7 7.9 17.7 0.0 17.8 24.3 16.4 7.4 14.9 19.7 24.7 38.1 16.0 9.2 12.1 15.5 21.3 9.6 15.1 47.7 14.7 13.8 16.9 17.8 31.8 14.7 14.5 32.3 9.7 24.5 23.8 13.6 44.2 14.1 22.7 5.6 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 34.1" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 24.4;Ciliated cells: 17.4;Muller glia cells: 29.9" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "eosinophil: 2.4;naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 10.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favorable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favorable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 0.6 2.7 2.0 0.3 2.9 0.1 0.9 2.3 1.8 1.4 0.6 0.0 1.8 34.1 0.2 3.4 0.3 1.0 1.8 3.7 2.2 0.5 0.7 0.4 1.6 4.1 0.8 3.6 1.8 1.3 1.3 0.3 0.3 1.5 0.0 0.5 0.5 1.1 1.4 0.9 0.3 1.3 3.2 0.5 0.7 0.5 0.9 0.0 2.4 0.0 0.6 2.4 0.1 0.0 0.8 5.4 1.6 2.7 1.4 0.0 0.9 0.4 1.0 1.3 1.7 0.7 0.0 6.4 1.2 1.1 0.3 1.4 0.6 1.6 1.7 0.1 1.4 0.3 0.0 1.1 3.3 0.3 5.5 0.1 0.6 0.0 0.4 0.3 4.1 4.1 4.1 0.9 3.5 3.2 1.7 6.7 0.0 0.3 4.6 1.0 2.1 1.3 0.2 0.0 1.1 1.5 0.2 5.0 10.2 1.3 1.7 0.2 2.1 2.9 0.5 0.1 6.5 2.6 1.3 1.4 1.8 1.4 0.0 0.0 2.4 0.3 0.0 0.0 0.6 0.6 0.0 0.0 0.9 2.4 0.2 0.0 0.6 0.0 0.0 0.0 0.1 3.0 5.6 0.0 1.7 0.8 24.4 5.0 0.0 17.4 3.4 3.5 5.9 3.4 8.3 1.0 0.3 5.8 0.0 0.0 0.0 2.1 4.3 1.1 1.1 0.8 6.1 6.4 3.5 4.9 3.9 0.8 3.7 2.5 5.0 0.0 0.3 29.9 0.3 0.0 7.8 12.2 15.2 0.0 3.9 3.6 6.7 0.4 2.3 1.7 0.2 0.4 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116438-5175034 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 18.2;testis: 29.0" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 19.3;Erythroid cells: 23.3;Spermatocytes: 19.2" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046969 Uncertain Vesicles NA NA Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.3 0.3 0.3 0.3 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.3 1.2 0.0 0.6 0.6 0.3 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.3 0.3 2.6 0.3 0.0 0.4 0.4 0.3 0.4 0.1 0.3 0.3 0.3 18.2 0.6 0.7 0.9 0.3 0.3 0.0 29.0 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.9 1.2 1.9 1.0 0.2 0.4 0.1 2.2 0.9 2.2 1.6 0.4 0.2 2.3 1.9 0.1 0.6 0.4 0.8 1.0 2.2 1.6 1.2 1.9 1.0 0.7 0.8 0.5 1.5 1.3 1.7 1.3 0.9 1.2 0.5 2.8 1.1 0.5 0.1 0.2 2.5 0.3 1.8 0.5 0.3 0.5 2.5 1.8 0.7 1.5 0.7 0.1 1.4 1.9 0.2 0.5 0.7 0.9 2.1 1.0 0.1 3.3 3.7 2.1 2.2 1.2 0.9 3.2 2.0 1.4 2.0 1.6 1.5 0.0 0.1 2.6 0.1 0.4 0.9 0.4 0.3 0.2 0.6 0.3 0.3 0.3 0.9 0.3 0.4 1.9 0.2 1.0 1.2 0.1 0.1 0.3 0.6 0.5 0.3 0.3 0.1 0.3 0.3 0.3 0.3 6.0 9.6 0.5 0.9 9.6 7.9 1.6 7.6 5.3 5.7 3.5 11.8 0.5 3.3 0.0 19.3 2.9 0.0 23.3 0.0 0.8 1.5 2.4 0.0 2.6 2.3 1.6 0.0 4.9 4.9 9.4 1.7 5.7 3.3 0.0 0.0 4.7 0.1 0.0 2.5 2.8 9.8 6.5 0.6 19.2 5.5 9.2 0.6 0.7 0.0 0.9 USP7 HAUSP ENSG00000187555 "Ubiquitin specific peptidase 7" Q93009 16 8892094-8964514 "Enzymes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Developmental protein, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 217.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008108, HPA015641, CAB079904" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "CAB008108: AB_2233500, CAB079904: AB_2552261, HPA015641: AB_1858700" "unprognostic (6.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.36e-3)" "unprognostic (1.94e-2)" "unprognostic (9.64e-2)" "unprognostic (8.09e-2)" "unprognostic (4.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.81e-1)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (9.93e-2)" "prognostic favorable (8.56e-5)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (7.31e-2)" "unprognostic (2.69e-1)" 17.8 16.8 23.9 25.8 22.9 37.6 21.3 28.7 24.5 21.2 26.3 16.2 18.4 17.7 23.5 16.4 24.4 20.3 18.7 23.7 22.8 20.8 16.5 21.3 21.0 30.5 19.6 22.6 22.5 24.0 44.4 19.7 19.3 16.2 18.5 27.4 16.0 18.4 20.3 42.2 25.2 21.5 22.7 15.3 22.9 22.6 43.3 16.5 68.8 19.5 22.3 35.1 23.9 31.7 7.5 9.8 5.5 7.8 3.9 8.7 1.8 12.4 23.3 20.6 15.4 11.7 15.0 14.2 17.2 14.8 16.1 13.7 20.8 15.3 30.1 11.0 19.9 9.2 15.6 31.5 20.6 27.0 19.7 12.5 25.0 15.7 42.9 16.9 27.5 16.2 12.9 13.1 17.5 20.7 12.4 22.8 45.5 24.1 33.4 16.4 23.8 40.3 5.3 14.4 15.8 13.5 35.9 23.1 27.5 11.3 24.5 19.5 12.0 19.3 18.2 9.5 22.0 18.1 12.3 19.5 17.5 17.9 26.8 12.9 16.2 39.6 46.0 16.3 16.0 14.0 5.5 3.3 3.8 7.1 3.2 8.7 5.9 6.6 8.2 3.3 7.5 8.0 6.8 5.2 3.9 7.8 9.8 7.0 1.8 23.9 22.9 28.7 24.5 22.8 20.8 19.6 22.6 16.2 16.5 32.8 46.2 23.4 19.2 41.3 47.4 61.8 20.4 46.8 46.6 27.9 23.6 18.4 5.0 21.1 217.0 25.9 29.6 46.7 28.3 12.6 24.0 27.0 25.5 34.2 17.5 41.3 40.6 25.2 28.0 84.4 23.6 28.5 18.6 16.2 46.7 25.0 27.8 28.8 32.5 11.8 41.6 6.5 29.2 29.9 31.9 43.7 17.6 26.6 47.0 32.7 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514419 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" NA NA "Golgi apparatus" Cytosol "HPA050215: AB_2681054" "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 19.4 21.9 21.0 20.6 20.6 21.6 18.1 27.3 21.6 21.4 23.9 13.8 19.5 20.2 22.1 17.4 22.3 17.4 15.5 17.4 19.7 18.2 28.2 26.4 17.0 25.4 21.8 15.2 21.9 16.7 42.6 43.2 29.1 29.7 16.7 18.9 10.7 19.9 17.9 24.3 17.8 32.1 19.2 29.3 30.3 17.7 27.5 26.1 28.9 24.1 12.7 20.9 22.3 18.4 16.7 10.6 38.1 15.1 9.5 11.9 6.9 11.2 16.2 9.1 16.0 16.6 18.7 12.6 16.2 19.2 15.8 18.7 10.8 7.5 11.9 12.5 18.5 17.8 21.8 12.4 12.1 18.7 10.4 8.2 21.9 15.1 11.0 17.1 14.7 14.9 14.4 14.6 13.9 23.6 14.7 15.3 8.5 12.5 14.5 14.8 23.1 9.4 5.8 10.4 12.9 7.5 8.5 16.9 17.8 15.0 26.5 11.6 10.6 17.0 25.5 21.2 20.1 14.0 18.0 17.3 16.4 9.2 50.5 21.3 11.3 23.4 13.1 13.1 29.7 15.8 38.1 13.3 22.4 11.1 12.4 10.7 16.5 11.4 11.1 10.6 16.7 11.9 10.7 22.7 9.5 15.1 9.9 8.5 6.9 21.0 20.6 27.3 21.6 19.7 18.2 21.8 15.2 29.7 26.1 89.3 104.5 61.4 35.4 25.6 51.6 61.8 48.4 147.2 88.7 45.4 64.8 49.9 21.6 44.4 53.0 44.9 70.6 23.3 44.6 38.3 35.3 38.8 83.3 45.5 40.2 31.8 51.2 53.4 59.1 12.4 49.8 49.2 38.8 52.3 54.2 53.3 45.7 54.3 58.0 40.7 75.6 45.3 42.6 86.1 47.1 36.3 88.0 47.9 55.0 52.6 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9, X-linked" Q93008 X 41085635-41236579 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles NA NA Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 18.0 21.8 17.7 14.0 15.9 15.5 16.8 16.6 16.7 18.4 20.6 11.4 25.4 13.2 19.6 19.0 17.3 17.0 17.1 20.9 14.2 14.2 18.5 34.2 16.7 23.1 15.2 15.4 15.7 16.5 45.8 17.0 41.1 12.9 13.4 14.4 13.9 14.2 25.2 42.8 14.8 22.0 17.3 14.0 16.7 16.9 16.9 14.0 21.1 20.3 17.6 16.5 20.3 19.9 6.4 5.5 13.0 5.0 4.9 7.8 3.1 18.2 21.6 19.2 19.6 16.1 16.9 4.4 10.5 14.1 12.0 13.9 9.9 8.5 12.3 5.9 23.9 35.9 12.4 32.9 19.1 20.1 15.4 23.6 14.2 20.9 8.9 13.6 12.3 10.4 14.6 8.6 28.7 27.2 17.2 18.5 8.3 17.2 10.0 18.5 13.3 8.8 4.9 20.3 6.5 11.9 9.7 26.2 7.9 11.4 15.1 10.9 10.2 44.2 12.2 12.0 36.0 11.8 6.9 19.7 18.3 14.2 17.3 11.3 9.2 10.7 15.7 13.1 5.5 9.1 3.3 4.7 6.0 5.6 4.2 7.8 6.4 6.6 6.2 5.5 4.7 6.7 6.0 13.0 4.9 5.0 4.2 5.6 3.1 17.7 15.9 16.6 16.7 14.2 14.2 15.2 15.4 12.9 14.0 38.7 32.0 23.8 26.8 42.8 35.0 73.6 43.3 30.8 36.4 26.2 35.3 31.0 6.6 26.8 13.0 39.8 39.2 70.0 22.8 21.8 35.1 30.2 24.4 55.5 29.3 35.0 25.8 52.8 43.4 13.1 30.8 38.0 32.1 33.3 42.5 32.0 27.0 35.7 46.3 20.3 29.3 32.3 39.6 31.4 69.2 48.3 39.0 26.1 36.7 34.3 USP9Y DFFRY ENSG00000114374 "Ubiquitin specific peptidase 9, Y-linked" O00507 Y 12701231-12860839 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 60.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.4;dendritic cells: 2.0;T-cells: 2.7" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 16.2;RT4: 8.7" "Not detected" "Not detected" HPA057687 Uncertain Vesicles NA NA Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 1.2 2.2 1.4 0.9 3.1 1.7 1.1 9.6 4.0 0.0 1.6 1.4 0.0 8.6 4.4 0.0 3.8 2.4 1.8 3.4 2.9 2.2 2.2 1.4 2.1 0.0 2.7 0.0 4.8 1.7 9.3 4.8 2.3 7.6 2.8 2.0 1.8 0.0 1.5 2.2 1.5 2.9 2.8 4.5 3.2 0.0 2.4 2.0 0.1 0.2 0.5 2.7 0.2 0.0 2.3 0.0 0.0 0.0 0.0 2.5 7.2 7.2 3.6 3.9 0.0 0.0 4.1 0.0 6.0 0.0 0.0 0.0 0.0 3.3 2.3 0.0 2.6 0.0 7.1 4.0 0.0 0.0 6.0 5.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 6.5 0.0 4.0 0.0 1.5 0.0 0.0 0.0 2.0 0.9 16.2 8.7 2.8 0.0 0.0 0.0 2.1 5.4 0.0 0.0 5.5 4.4 0.0 0.0 3.2 0.0 3.8 7.1 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.2 2.7 1.2 2.2 1.5 0.3 2.4 2.2 1.3 0.1 0.5 0.0 2.0 1.6 0.2 23.8 19.7 0.8 7.4 10.4 22.1 24.6 2.5 21.4 15.9 19.2 60.9 4.3 1.7 4.1 0.4 5.8 0.0 0.0 0.0 1.1 9.3 11.2 2.3 0.2 2.5 25.4 0.0 5.5 6.9 0.0 11.5 7.3 3.3 2.8 0.3 8.1 3.7 0.0 14.5 5.4 24.9 0.0 7.6 3.2 1.7 10.2 2.9 10.0 0.0 9.9 VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35056064-35073249 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Syncytiotrophoblasts: 452.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Enhanced Nucleoplasm,Cytosol No No 110000000 "Nucleoplasm, Cytosol" "CAB005593: AB_2214638, HPA012728: AB_1858730, HPA012814: AB_1858729" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.15e-2)" "prognostic favorable (7.30e-4)" "unprognostic (5.78e-2)" "unprognostic (1.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-2)" "unprognostic (2.19e-2)" "unprognostic (3.24e-1)" "prognostic favorable (9.63e-7)" "unprognostic (1.83e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (9.11e-2)" 33.7 43.6 19.6 30.3 21.8 30.8 31.4 19.4 31.0 32.2 25.7 22.7 32.9 22.2 30.5 34.0 40.0 24.7 33.8 69.6 20.0 23.4 30.1 63.4 27.6 42.7 23.1 21.1 25.0 34.9 44.5 29.0 46.3 26.3 33.4 26.5 21.2 30.7 34.1 80.4 29.2 26.3 29.2 23.0 37.8 28.9 25.6 18.2 43.3 32.1 42.2 35.7 31.5 26.5 25.9 29.4 43.4 30.6 23.0 32.1 34.4 36.0 41.2 28.4 15.3 34.3 24.2 21.7 33.6 38.1 50.3 37.2 27.5 14.9 28.6 29.5 41.7 44.2 17.4 42.3 40.1 43.6 30.7 24.5 19.9 39.0 37.6 26.7 22.3 26.6 27.6 27.0 43.6 19.5 21.1 54.4 13.1 20.6 20.8 40.2 25.4 21.8 53.7 37.0 18.7 39.4 19.4 22.1 17.7 39.3 25.8 15.5 19.5 20.3 23.0 10.2 36.9 18.5 15.9 44.5 20.2 26.1 17.9 29.5 10.6 22.4 24.5 33.1 16.1 25.8 43.4 24.5 31.9 24.7 27.2 23.8 25.9 23.6 24.8 29.4 21.1 17.7 18.5 28.4 23.0 30.6 18.9 32.1 34.4 19.6 21.8 19.4 31.0 20.0 23.4 23.1 21.1 26.3 18.2 74.5 72.0 80.5 100.9 68.5 80.1 178.9 43.3 71.0 68.2 52.4 111.9 240.5 63.0 177.8 24.1 121.1 90.3 23.3 162.4 147.5 81.6 98.2 61.1 102.4 116.5 69.9 80.8 122.8 57.9 36.5 77.6 66.7 72.6 234.4 63.9 87.7 195.1 56.3 81.7 89.3 82.6 135.8 82.4 127.7 117.9 79.3 452.1 76.6 57.1 105.3 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667217 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Plasma membrane" Centrosome "HPA023932: AB_2671373" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 9.5 8.7 15.7 12.6 14.5 30.9 8.9 14.4 15.1 7.5 8.4 7.0 3.8 7.0 7.8 8.7 8.1 6.9 7.0 6.7 10.2 9.2 8.3 12.3 10.5 13.6 10.3 13.7 7.8 9.0 14.0 5.9 8.0 12.3 7.0 7.8 6.0 9.0 7.1 14.8 7.3 10.0 6.3 9.6 14.7 8.0 10.8 11.7 11.6 8.0 2.8 13.3 7.9 7.0 2.6 3.4 11.3 8.8 2.8 4.3 1.7 9.0 8.2 4.2 5.6 13.0 9.2 4.1 7.3 7.4 5.6 6.5 4.8 8.5 12.2 2.1 9.7 6.9 8.0 6.8 6.1 8.0 9.0 4.9 13.5 8.1 6.0 7.8 4.5 14.6 9.9 9.0 6.1 11.1 6.9 6.0 6.7 9.1 11.8 8.2 4.4 9.7 7.8 8.0 7.6 5.7 6.3 6.6 6.1 8.1 7.1 2.5 4.8 5.6 8.6 6.3 5.6 8.8 7.5 12.0 7.4 5.5 6.5 4.8 10.5 5.1 13.1 7.3 6.5 5.5 9.2 3.2 6.7 4.3 5.2 3.6 2.0 2.7 3.1 3.4 2.6 2.2 2.9 11.3 2.8 8.8 1.3 3.3 1.7 15.7 14.5 14.4 15.1 10.2 9.2 10.3 13.7 12.3 11.7 17.9 14.6 9.0 8.1 15.0 11.1 16.5 12.7 12.0 11.4 7.0 21.6 8.8 3.3 9.7 4.3 9.9 14.0 23.3 11.7 4.8 12.3 11.3 18.5 20.2 12.4 11.1 5.8 15.4 47.5 4.5 7.5 18.0 10.1 10.8 15.0 11.8 10.8 15.3 14.9 9.9 10.8 6.5 10.8 26.8 14.7 18.1 8.2 26.6 13.3 14.2 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132681590-132714049 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 131.9;liver: 112.2" "Group enriched" "Detected in many" 5 "Cholangiocytes: 71.4;Ductal cells: 179.6;Hepatocytes: 68.4;Pancreatic endocrine cells: 77.2" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "classical monocyte: 13.4" "Group enriched" "Detected in many" 71 "dendritic cells: 4.9;granulocytes: 8.0;monocytes: 13.4" "Cell line enhanced" "Detected in some" "A-431: 4.1;CAPAN-2: 4.3;EFO-21: 15.1;HBEC3-KT: 4.0;LHCN-M2: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064145 Uncertain "Intracellular and membrane" NA NA 1100000000 "HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 1.8 0.4 0.3 0.6 0.3 2.4 0.7 0.2 0.3 0.4 128.6 0.1 0.0 40.6 2.5 0.2 0.6 1.7 27.0 1.1 0.3 0.3 6.5 112.2 7.9 2.4 0.4 0.1 0.4 0.9 0.0 0.3 1.0 0.5 0.4 0.3 0.2 1.5 0.1 0.4 0.5 131.9 0.0 0.5 5.6 0.8 0.5 0.1 0.2 0.4 0.0 0.4 0.4 0.9 0.1 4.9 8.0 13.4 0.0 0.0 3.6 4.1 0.0 0.5 0.1 0.1 1.3 0.9 0.3 0.3 0.0 0.0 0.1 4.3 0.2 15.1 0.0 0.8 0.1 0.0 4.0 1.1 0.1 0.0 0.2 0.2 2.3 2.3 0.3 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 4.3 0.2 0.0 0.6 0.1 0.1 0.2 0.1 0.2 1.8 0.9 0.3 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.7 1.0 0.1 0.5 0.2 0.4 0.0 0.1 0.5 0.1 0.6 2.3 13.4 0.0 0.0 7.4 0.0 0.0 0.0 0.0 4.9 0.1 0.0 0.0 8.0 0.0 10.2 0.2 0.0 3.6 0.3 0.3 0.2 0.3 0.3 0.3 0.4 0.1 0.5 0.1 0.0 4.8 0.0 0.0 1.1 0.0 0.3 71.4 1.4 1.2 1.8 0.0 0.0 0.0 179.6 0.0 0.0 13.2 0.0 17.0 0.1 0.2 3.1 0.0 68.4 13.9 0.0 0.0 0.6 13.9 0.0 0.0 10.6 0.0 5.4 4.3 0.0 77.2 0.9 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 9.9 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 85.2;lung: 36.4;lymphoid tissue: 43.6" "Cell type enhanced" "Detected in many" 11 "Ciliated cells: 17.4;Ductal cells: 36.1;Kupffer cells: 27.8;Macrophages: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "neutrophil: 85.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 85.2" "Cell line enriched" "Detected in some" 8 "Daudi: 35.7" "Not detected" "Not detected" NA NA 270000 "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 10.1 1.4 1.1 9.5 1.1 10.8 1.4 1.4 1.4 1.8 1.9 0.8 0.0 0.7 0.9 3.1 2.1 4.3 10.2 10.5 1.1 1.1 2.8 5.6 36.4 39.8 3.8 0.3 2.1 2.4 0.0 1.2 8.6 1.5 2.4 0.9 1.8 1.3 0.2 1.0 0.7 3.6 2.4 2.2 43.6 2.8 3.6 0.6 3.4 1.4 0.7 17.7 7.3 10.9 6.4 2.2 85.2 10.9 5.8 6.7 5.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.9 0.0 0.0 1.5 10.9 0.0 4.2 2.4 1.7 6.4 1.4 4.9 2.2 5.5 4.5 6.7 85.2 5.8 1.5 0.4 0.9 5.7 1.1 1.1 1.4 1.4 1.1 1.1 3.8 0.3 1.5 0.6 0.0 10.7 0.0 0.0 0.0 0.0 1.2 2.5 17.4 3.4 0.0 0.0 0.6 0.0 36.1 0.0 0.0 0.0 0.0 0.3 0.1 0.5 5.6 4.7 0.0 11.3 0.0 0.0 4.3 27.8 0.0 0.0 17.1 0.0 1.8 0.0 0.0 4.0 0.0 0.0 0.3 0.0 6.5 0.5 0.0 0.0 0.0 1.1 6.1 0.0 8.4 VNN3 HSA238982 ENSG00000093134 "Vanin 3" Q9NY84 6 132722787-132734765 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "blood: 39.5;bone marrow: 29.8;liver: 29.4" "Group enriched" "Detected in some" 5 "Ciliated cells: 69.6;Club cells: 19.4" "Cancer enhanced" "Detected in some" "liver cancer: 3.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "neutrophil: 39.5" "Lineage enriched" "Detected in single" 40 "granulocytes: 39.5" "Cell line enhanced" "Detected in some" "Daudi: 2.5;EFO-21: 3.7;GAMG: 1.6;hTCEpi: 2.3" "Secreted to blood" NA NA 150000000 "unprognostic (3.20e-2)" "unprognostic (2.70e-1)" "unprognostic (7.92e-3)" "unprognostic (1.71e-2)" "unprognostic (3.05e-3)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (5.84e-8)" "unprognostic (1.25e-2)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" 1.1 0.1 0.4 3.3 0.4 29.8 0.2 0.2 0.6 2.4 1.2 0.2 0.2 0.0 0.2 0.8 0.9 2.4 1.3 1.0 0.4 0.0 0.3 29.4 6.1 1.2 0.4 0.2 1.2 0.2 0.0 0.2 5.8 0.3 0.5 0.0 0.4 1.1 0.2 0.2 0.1 0.2 0.2 0.2 7.6 0.4 0.3 0.2 0.2 0.3 2.4 0.7 0.6 0.3 0.0 0.0 39.5 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 2.5 3.7 0.0 1.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 6.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.6 0.4 0.0 0.4 0.2 0.3 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 69.6 19.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 9.7 0.1 0.0 0.0 0.6 9.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 VPS4A "FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1" ENSG00000132612 "Vacuolar protein sorting 4 homolog A" Q9UN37 16 69311356-69326939 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB018751, CAB034411, HPA060092" Approved Supported Midbody NA NA Midbody "CAB018751: AB_2215497, CAB034411: AB_2304400, HPA060092: AB_2684203" "unprognostic (2.60e-2)" "unprognostic (2.32e-2)" "unprognostic (1.26e-1)" "unprognostic (9.26e-2)" "unprognostic (4.03e-1)" "unprognostic (1.20e-1)" "unprognostic (2.55e-2)" "unprognostic (2.70e-2)" "unprognostic (4.63e-2)" "unprognostic (8.61e-2)" "unprognostic (3.91e-3)" "unprognostic (2.19e-1)" "prognostic favorable (1.76e-4)" "unprognostic (5.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.61e-1)" "unprognostic (6.79e-2)" 20.2 19.6 24.8 14.4 26.5 13.0 24.2 28.7 35.6 12.9 17.8 19.3 14.5 22.0 16.6 14.5 26.3 16.0 16.1 34.3 24.4 22.8 23.2 13.7 15.8 17.5 25.4 29.3 21.0 31.4 29.7 9.6 16.6 33.6 17.5 13.2 15.6 30.4 15.5 81.6 24.3 20.5 18.4 34.3 15.0 18.9 15.5 17.4 8.9 27.5 21.1 13.0 15.6 21.2 11.1 11.6 15.7 13.1 9.3 18.1 14.4 11.0 19.0 13.2 17.3 11.9 10.6 11.5 15.1 13.7 20.1 13.5 17.9 10.5 18.8 15.1 15.0 9.9 16.7 13.0 15.2 12.2 7.8 16.9 11.8 11.4 14.4 18.5 14.7 11.0 12.2 20.0 17.4 15.9 12.3 14.9 15.2 19.5 5.7 14.8 24.8 19.0 11.1 14.9 11.2 13.4 25.7 10.6 22.0 10.1 9.1 22.0 14.0 32.3 10.1 11.5 9.2 17.6 11.1 17.7 18.6 11.7 16.9 11.7 20.5 16.2 34.1 17.1 10.0 20.4 10.0 11.6 15.7 14.6 10.2 13.3 11.1 12.3 18.1 11.6 10.1 14.3 13.0 9.5 9.3 13.1 6.8 13.8 14.4 24.8 26.5 28.7 35.6 24.4 22.8 25.4 29.3 33.6 17.4 23.8 21.3 28.2 30.2 27.2 53.3 26.2 20.4 5.3 11.4 22.7 21.6 49.8 63.0 45.4 7.2 30.7 47.9 0.0 71.8 54.7 29.7 38.7 28.8 20.2 39.8 69.9 30.1 27.0 23.4 7.7 27.3 27.5 42.2 45.9 31.5 52.2 53.2 38.7 28.7 46.3 36.1 51.8 37.6 27.3 33.4 27.4 58.6 36.7 35.7 36.3 VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved "Vesicles,Intermediate filaments" No No 34000 Vesicles "Intermediate filaments" "CAB046445: AB_10603252, HPA040393: , HPA057649: AB_2683489" "unprognostic (8.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.10e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.23e-4)" "unprognostic (4.59e-1)" "unprognostic (1.40e-1)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" 16.8 13.0 14.3 14.3 17.2 28.0 17.2 15.4 19.1 19.8 24.0 21.8 15.5 20.0 16.7 12.1 55.0 13.1 15.1 9.9 13.7 16.0 15.6 20.5 14.3 21.6 17.0 14.7 11.9 14.0 17.5 17.4 27.4 23.4 14.3 22.2 9.3 21.8 15.0 9.9 22.1 28.7 15.2 20.2 17.3 18.7 9.0 14.6 27.8 17.0 17.6 31.8 18.6 24.7 20.7 13.6 56.4 20.6 19.1 18.9 15.4 18.7 6.9 7.7 8.4 12.0 17.0 13.5 16.5 15.6 12.6 13.8 5.1 13.4 18.1 10.8 12.0 10.7 40.8 9.2 18.0 16.8 13.1 7.5 9.0 9.7 7.9 17.2 31.1 19.8 15.4 28.1 11.1 19.8 12.8 11.7 10.5 4.5 17.0 17.9 6.5 19.4 9.8 8.0 7.6 10.9 16.3 16.4 17.4 15.9 22.0 13.2 11.7 12.4 12.2 18.4 10.3 11.7 17.0 18.0 19.5 9.5 7.3 10.8 57.1 27.4 23.3 11.2 14.7 14.5 39.4 16.8 36.0 16.5 16.6 15.4 18.9 17.4 17.0 13.6 20.7 15.8 16.6 56.4 19.1 20.6 13.6 18.9 15.4 14.3 17.2 15.4 19.1 13.7 16.0 17.0 14.7 23.4 14.6 107.2 43.6 46.5 38.8 61.1 39.4 35.8 45.9 89.7 64.8 31.4 21.6 56.4 38.1 41.7 73.2 41.4 81.3 23.3 36.8 46.3 33.4 30.3 55.7 52.3 40.7 41.3 43.7 33.7 56.7 9.1 45.5 48.9 30.4 30.7 72.2 37.9 63.8 86.0 34.3 37.8 28.4 58.2 32.9 26.0 26.6 72.9 117.4 69.2 60.0 67.1 WDYHV1 "C8orf32, FLJ10204" ENSG00000156795 "WDYHV motif containing 1" Q96HA8 8 123416725-123467230 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 39.8" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: AB_2682228" "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" 10.5 15.5 13.2 7.9 13.6 6.3 17.2 14.3 16.8 14.5 9.9 13.9 10.7 5.8 11.2 12.0 10.2 9.8 8.8 24.8 12.8 19.8 13.6 9.1 8.6 11.4 17.0 10.8 20.4 21.3 9.0 12.8 8.2 16.2 13.5 9.5 9.7 8.3 12.5 19.2 9.8 5.4 13.0 17.0 7.9 10.0 17.5 15.6 5.3 14.4 9.1 11.3 10.1 9.1 5.9 7.2 8.7 7.5 13.1 9.2 5.5 9.1 10.8 12.7 6.7 5.5 12.6 5.7 7.6 6.7 7.2 9.2 6.4 6.1 7.3 6.9 5.3 10.2 5.3 8.1 8.8 9.7 17.2 7.1 7.9 5.2 8.7 7.7 3.0 3.4 8.5 5.4 9.6 11.8 9.3 7.2 13.8 5.9 10.1 10.6 28.5 8.8 6.2 5.1 21.2 7.4 5.1 8.0 5.8 9.6 8.1 6.5 14.1 7.8 39.8 12.1 14.3 6.6 3.3 3.9 9.6 15.1 7.1 9.2 7.6 15.4 9.0 7.8 4.6 6.0 8.7 6.3 2.5 7.8 7.5 8.4 5.2 8.4 7.3 7.2 5.9 6.5 7.4 1.8 13.1 4.0 4.6 9.2 5.5 13.2 13.6 14.3 16.8 12.8 19.8 17.0 10.8 16.2 15.6 3.0 6.7 12.0 8.7 6.6 5.4 16.2 7.6 1.4 5.7 14.0 2.0 10.4 33.2 10.5 7.6 8.2 3.3 0.0 13.2 18.4 7.7 13.3 8.1 4.2 12.0 4.8 0.0 10.4 9.5 11.5 8.1 7.2 10.1 9.0 6.2 6.0 10.4 9.1 11.0 11.2 7.2 12.9 11.3 20.6 28.7 7.9 8.4 4.3 8.8 8.7 WRN "RECQ3, RECQL2" ENSG00000165392 "Werner syndrome RecQ like helicase" Q14191 8 31033801-31173769 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 10.1 9.2 5.6 8.5 6.6 15.6 11.1 10.7 7.3 14.2 8.0 7.7 7.7 5.5 24.4 8.8 7.6 9.7 6.9 7.0 5.9 4.0 5.1 7.7 7.2 6.7 8.2 5.3 12.0 9.9 7.8 28.1 8.5 7.0 8.6 7.8 8.3 10.8 7.8 7.7 10.2 7.0 12.1 14.9 8.9 8.3 10.4 7.3 11.8 7.9 6.3 9.3 10.8 8.7 3.9 2.7 1.3 1.9 2.9 6.2 1.6 6.5 6.4 13.3 8.4 8.0 12.8 8.4 7.4 7.3 9.1 9.5 4.1 4.0 15.4 6.8 7.5 6.9 3.4 8.2 5.3 13.6 4.3 7.0 15.7 6.1 3.4 10.0 9.3 5.8 9.3 5.9 8.6 10.4 4.5 8.7 10.8 24.8 9.7 8.3 4.2 19.3 4.5 11.4 7.1 4.6 11.1 10.1 6.2 3.8 7.2 2.9 7.7 9.0 5.1 7.0 7.8 3.5 4.6 13.9 9.9 6.1 5.0 6.2 2.6 2.8 19.3 7.3 7.3 6.8 1.2 1.9 1.3 3.3 1.9 6.2 3.9 3.8 3.3 2.7 3.5 2.5 3.2 0.5 2.9 0.8 2.0 2.8 1.6 5.6 6.6 10.7 7.3 5.9 4.0 8.2 5.3 7.0 7.3 8.9 8.8 10.8 8.0 11.9 14.2 6.5 12.7 9.4 11.4 15.7 21.6 5.9 1.7 5.1 37.8 8.5 3.2 23.3 8.4 4.7 10.8 8.1 2.3 8.9 4.5 14.3 2.4 6.2 5.1 8.1 17.5 4.9 10.1 5.4 12.1 21.9 7.1 2.9 13.4 2.1 22.1 6.5 9.5 8.7 18.6 8.9 4.7 5.1 7.6 9.8 WRNIP1 "bA420G6.2, FLJ22526, WHIP" ENSG00000124535 "Werner helicase interacting protein 1" Q96S55 6 2765414-2786952 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm No No Nucleoplasm "HPA031752: AB_10603004, HPA031753: AB_2674028" "unprognostic (5.52e-2)" "unprognostic (5.95e-2)" "unprognostic (6.83e-3)" "unprognostic (8.35e-3)" "unprognostic (7.66e-2)" "unprognostic (7.10e-2)" "unprognostic (5.63e-3)" "unprognostic (3.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (1.81e-1)" "unprognostic (6.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" 15.4 23.1 29.9 19.8 32.1 31.2 22.4 42.5 33.5 22.2 21.9 23.3 25.7 17.7 19.8 29.7 32.8 28.0 24.7 28.8 30.9 30.1 23.3 25.8 21.2 23.4 27.4 26.2 23.2 37.4 39.2 31.2 32.3 21.3 22.5 22.6 23.9 34.6 22.0 29.0 27.8 19.6 18.5 20.2 20.7 19.3 24.6 24.2 34.1 31.6 36.0 25.3 18.8 29.2 3.4 4.2 9.1 2.8 3.7 6.5 2.3 31.5 15.9 16.2 26.5 17.2 14.9 21.6 14.5 20.4 26.8 26.7 25.1 14.8 28.4 39.7 18.7 29.1 24.6 26.5 29.2 26.2 28.3 29.1 29.7 18.1 39.2 19.6 18.6 20.6 15.1 23.9 24.6 26.8 18.7 33.9 27.0 22.6 10.3 19.5 30.9 27.5 33.8 13.9 21.8 19.8 22.0 23.7 28.8 28.4 19.5 49.0 14.0 17.2 17.5 33.8 26.7 22.5 21.0 18.4 20.1 15.2 17.4 35.1 13.3 23.1 22.1 7.9 20.3 27.2 9.1 2.6 3.4 6.5 2.8 2.1 3.4 4.7 4.8 2.1 2.4 5.5 5.2 1.1 3.7 1.4 4.2 6.5 2.3 29.9 32.1 42.5 33.5 30.9 30.1 27.4 26.2 21.3 24.2 17.9 10.5 3.7 10.8 28.8 23.9 17.3 35.7 21.4 7.9 10.4 7.9 26.5 3.3 12.6 42.1 18.0 18.7 0.0 11.8 20.2 14.8 14.5 9.2 21.9 11.1 7.9 38.2 30.1 13.8 11.0 20.8 12.7 20.3 7.2 24.1 18.0 15.9 11.5 20.8 11.3 16.5 6.5 11.8 21.4 24.7 28.1 21.3 4.5 23.0 13.2 XPNPEP1 "XPNPEP, XPNPEPL, XPNPEPL1" ENSG00000108039 "X-prolyl aminopeptidase 1" Q9NQW7 10 109864766-109923553 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025196, HPA030419, HPA030420, HPA030422" Supported Enhanced Cytosol NA NA 760000 Cytosol "CAB025196: , HPA030419: AB_10598917, HPA030420: AB_10611523, HPA030422: AB_10601783" "unprognostic (3.17e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (2.46e-1)" "unprognostic (2.01e-3)" "prognostic unfavorable (2.12e-5)" "unprognostic (8.03e-2)" "unprognostic (2.10e-2)" "unprognostic (1.88e-1)" "unprognostic (4.89e-2)" "unprognostic (7.61e-2)" "unprognostic (2.43e-2)" "unprognostic (1.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (5.18e-2)" 16.6 14.7 13.4 16.1 18.9 12.8 13.6 14.8 22.2 15.7 20.6 19.5 14.1 33.2 17.5 16.1 17.8 15.8 20.3 17.8 13.7 11.4 18.3 21.0 14.8 14.9 13.8 14.0 17.8 46.0 14.9 15.9 19.0 17.2 16.0 26.9 15.6 19.6 11.3 18.5 20.4 38.6 18.6 11.9 18.0 16.8 15.1 12.0 9.9 15.7 15.2 24.2 14.1 13.8 5.5 24.0 10.0 21.0 14.7 10.6 13.4 25.5 11.2 18.0 24.5 29.4 27.6 13.8 14.2 29.1 21.4 23.2 21.8 22.0 36.5 12.3 21.9 10.9 13.6 14.2 17.6 21.0 10.8 13.7 24.3 7.3 9.0 20.5 18.9 20.3 27.2 10.9 23.5 20.9 32.9 35.1 23.7 7.9 11.7 27.1 8.6 13.5 11.8 7.0 19.4 12.2 15.1 36.3 6.5 27.2 8.0 5.5 20.9 12.4 7.9 23.8 20.5 9.6 17.7 18.0 8.7 11.4 13.8 12.5 19.9 9.7 31.2 20.6 26.5 6.9 10.0 13.7 5.6 10.6 21.0 7.3 5.5 7.0 9.5 24.0 4.8 5.0 6.6 1.1 14.7 17.5 18.8 7.5 13.4 13.4 18.9 14.8 22.2 13.7 11.4 13.8 14.0 17.2 12.0 6.0 15.6 11.9 11.4 7.9 19.1 15.7 20.4 12.0 10.3 3.5 5.9 33.7 14.9 29.4 4.5 12.1 36.7 0.0 63.7 24.7 19.7 19.6 10.5 9.6 27.2 25.4 16.1 16.5 16.1 4.1 17.0 17.4 8.5 39.7 34.2 24.9 47.2 35.3 28.0 18.8 18.4 12.9 8.8 8.4 37.1 7.5 21.1 20.8 34.1 19.3 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738974-129769538 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "intestine: 145.6;kidney: 49.7" "Cell type enhanced" "Detected in some" 23 "Enterocytes: 21.3;Hepatocytes: 11.6;Proximal tubular cells: 49.7" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.3;liver cancer: 18.3;stomach cancer: 3.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 7.3;intermediate monocyte: 2.1;MAIT T-cell: 2.2;memory CD4 T-cell: 2.4;memory CD8 T-cell: 4.8;naive CD8 T-cell: 3.6;non-classical monocyte: 4.4;T-reg: 2.2" "Group enriched" "Detected in many" 7 "monocytes: 4.4;T-cells: 7.3" "Cell line enhanced" "Detected in some" "ASC diff: 6.3;ASC TERT1: 33.4;HSkMC: 16.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 8900000 "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 4.7 0.5 0.0 1.1 0.1 0.0 3.2 0.0 0.1 1.7 57.4 0.1 0.8 37.0 1.2 1.7 4.2 3.4 1.3 2.6 0.0 0.0 49.7 8.0 1.0 1.2 0.0 0.0 3.5 0.9 0.0 0.0 0.6 0.1 3.6 2.0 0.7 0.7 0.3 1.6 2.1 145.6 2.5 0.1 0.2 1.7 1.2 0.0 0.1 0.9 1.4 0.3 4.0 10.7 0.4 0.8 0.2 4.4 0.0 7.3 1.3 0.0 0.0 0.5 0.0 6.3 33.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 7.3 2.1 2.2 0.0 2.4 4.8 0.3 0.4 0.7 3.6 0.2 0.0 4.4 0.8 2.2 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.6 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 5.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 4.4 0.0 0.0 11.6 0.7 0.0 1.2 0.6 0.3 0.0 0.0 0.0 1.7 0.0 0.9 0.0 0.0 5.8 0.0 49.7 0.0 0.0 0.2 0.0 0.0 0.9 1.0 0.0 0.2 0.0 XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 196.2;Late spermatids: 233.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000527 Approved Supported Mitochondria,Cytosol NA NA Mitochondria Cytosol "HPA000527: AB_1079266" "prognostic unfavorable (8.19e-4)" "unprognostic (6.77e-2)" "unprognostic (3.22e-3)" "unprognostic (5.03e-3)" "unprognostic (6.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.24e-1)" 8.2 13.6 7.5 5.8 9.2 4.7 9.7 5.2 7.8 7.3 6.1 10.8 11.6 32.3 10.7 12.3 7.2 9.4 10.5 11.2 7.6 7.1 9.8 19.0 6.6 10.6 7.9 6.1 10.7 10.5 8.0 15.0 6.1 10.7 7.3 6.2 9.3 8.5 13.6 12.0 11.5 20.9 7.1 9.3 7.7 6.8 18.9 8.2 11.5 9.1 7.3 8.8 12.6 8.2 5.9 6.0 6.4 10.0 1.2 4.4 4.0 3.3 4.7 3.2 7.1 9.0 6.0 2.2 4.1 3.1 2.3 2.3 3.9 2.1 6.5 2.3 7.9 9.7 7.6 6.0 3.2 3.4 3.9 12.4 4.2 9.3 7.3 4.1 7.4 0.7 5.3 5.0 7.2 4.3 3.5 4.0 4.6 3.5 5.9 4.9 5.0 3.5 3.9 1.9 6.0 9.6 4.9 4.3 3.7 6.5 4.4 2.8 2.5 4.1 6.1 3.8 3.5 7.1 3.4 4.0 4.7 4.1 4.3 2.4 5.6 4.2 7.9 7.2 9.6 3.2 4.0 4.4 4.4 3.4 3.9 1.8 5.9 2.1 2.2 3.1 3.7 4.4 3.3 6.4 1.2 10.0 6.0 3.0 4.0 7.5 9.2 5.2 7.8 7.6 7.1 7.9 6.1 10.7 8.2 6.0 21.2 6.5 6.9 11.7 14.9 17.6 20.4 29.4 13.6 8.7 17.7 17.8 13.3 11.7 196.2 11.7 4.2 0.0 14.7 16.0 11.3 6.7 13.9 32.1 12.4 15.9 13.3 11.1 13.5 233.7 18.4 13.0 16.9 2.8 9.5 12.1 10.8 9.7 14.5 18.6 19.3 32.3 13.2 50.5 32.5 14.3 16.7 5.0 10.6 6.2 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 69.8;Urothelial cells: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 40.3;K-562: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 40000 "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 4.5 4.6 4.0 4.0 5.3 44.7 6.6 4.8 7.5 6.1 3.9 7.6 2.6 4.1 4.0 3.1 24.5 3.7 3.5 5.0 4.0 2.2 4.5 5.2 9.4 4.2 7.1 4.4 3.5 3.6 2.5 5.1 6.3 5.1 3.4 4.0 3.4 9.7 3.0 6.5 14.9 4.8 2.7 8.5 5.2 8.4 5.6 6.9 14.3 5.8 10.0 8.2 5.8 12.3 0.5 1.3 3.9 1.5 1.2 1.8 0.9 5.4 2.9 4.6 2.7 1.6 2.1 9.0 3.6 2.8 2.7 2.8 5.5 5.6 2.8 1.5 2.2 1.3 6.0 0.0 4.4 3.1 2.3 4.9 40.3 11.9 2.6 1.5 5.2 14.2 1.5 3.4 2.2 8.6 3.2 2.4 5.9 28.0 0.0 2.3 0.0 4.6 2.9 4.4 2.2 6.5 2.3 0.2 2.1 2.7 6.1 2.4 5.3 5.9 6.9 7.7 4.2 2.4 3.7 1.1 2.4 6.2 1.9 4.7 4.6 0.2 4.2 2.8 0.0 1.6 3.9 1.2 2.0 1.1 1.5 1.5 0.4 1.7 0.9 1.3 0.5 1.4 1.8 2.9 1.2 1.0 0.7 0.8 0.9 4.0 5.3 4.8 7.5 4.0 2.2 7.1 4.4 5.1 6.9 38.7 9.8 0.8 21.4 28.0 7.8 5.3 5.1 13.4 5.7 1.8 3.9 2.3 1.7 3.8 28.6 3.5 9.8 46.7 9.3 2.7 5.7 29.8 8.1 5.4 2.4 11.1 8.5 3.7 8.5 69.8 1.4 6.4 13.5 1.8 3.5 4.2 15.5 4.9 2.1 5.4 16.2 6.5 3.1 8.8 4.1 35.1 1.5 7.5 5.4 62.9 YTHDC2 "DKFZp564A186, FLJ10053, FLJ2194" ENSG00000047188 "YTH domain containing 2" Q9H6S0 5 113513683-113595285 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 92.8;Spermatocytes: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037364, HPA072678" Approved Approved "Nucleoplasm,Nuclear bodies,Cytoplasmic bodies" NA NA Nucleoplasm "Nuclear bodies, Cytoplasmic bodies" "HPA037364: AB_10672788, HPA072678: AB_2686548" "unprognostic (2.09e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.82e-5)" "unprognostic (4.33e-3)" "unprognostic (1.45e-1)" "unprognostic (6.48e-3)" "unprognostic (1.96e-1)" "unprognostic (7.82e-3)" "unprognostic (3.55e-2)" "unprognostic (8.56e-3)" "unprognostic (4.61e-2)" "unprognostic (2.03e-1)" "unprognostic (4.15e-2)" "unprognostic (3.05e-1)" "unprognostic (9.96e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" 15.2 16.3 12.4 18.5 16.8 12.8 15.3 25.2 26.1 16.5 12.7 11.7 9.0 13.6 17.7 14.6 16.1 14.2 12.2 13.0 10.4 10.5 14.3 18.3 12.4 18.7 12.8 10.2 19.9 14.7 35.5 26.2 10.3 18.6 12.8 15.3 14.9 15.5 13.3 18.5 16.5 16.5 13.2 13.7 19.3 13.4 20.5 13.3 19.7 16.2 15.4 18.4 14.7 14.8 9.5 5.5 4.2 4.9 5.7 5.7 1.7 11.1 10.1 13.1 22.2 7.3 9.7 14.4 8.7 9.6 11.1 17.4 7.0 6.3 20.4 6.2 7.2 14.3 10.9 15.8 19.4 14.6 8.8 14.3 11.1 18.1 9.5 10.8 8.8 9.8 7.9 7.5 7.0 12.8 10.5 15.4 9.3 10.8 9.4 9.8 3.7 12.2 6.3 6.1 3.3 6.7 5.2 11.4 15.8 9.3 14.8 10.5 8.8 11.6 8.5 8.9 8.6 12.0 8.0 13.4 17.1 6.0 8.8 11.7 9.7 12.1 12.8 9.8 10.1 7.2 0.0 4.3 4.2 4.5 2.8 5.3 9.5 5.3 4.8 3.6 8.1 5.7 4.7 1.8 5.7 4.9 5.5 3.7 1.7 12.4 16.8 25.2 26.1 10.4 10.5 12.8 10.2 18.6 13.3 26.8 29.1 18.2 17.4 11.7 58.8 17.3 12.7 28.1 30.7 12.2 78.5 11.1 0.0 15.3 22.0 18.5 11.2 23.3 16.5 8.1 14.7 12.8 11.6 19.7 14.4 49.3 6.9 20.9 27.6 37.6 18.4 18.8 11.8 17.2 13.0 25.3 13.7 7.0 13.8 15.2 92.8 25.8 19.4 97.9 24.0 12.5 15.1 21.2 13.6 15.2 ZMPSTE24 "FACE-1, HGPS, PRO1, STE24, Ste24p" ENSG00000084073 "Zinc metallopeptidase STE24" O75844 1 40258107-40294184 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006988 Approved NA NA 13000 "HPA006988: AB_1080659" "unprognostic (6.32e-2)" "unprognostic (1.63e-2)" "unprognostic (3.75e-3)" "unprognostic (4.63e-2)" "unprognostic (4.16e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.73e-6)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.84e-3)" "unprognostic (4.78e-2)" "unprognostic (7.96e-2)" "unprognostic (5.06e-2)" "unprognostic (3.65e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (2.71e-2)" 21.6 24.2 17.6 15.4 19.6 6.5 18.6 10.7 21.3 20.9 20.6 14.9 27.0 17.9 29.7 19.7 21.4 19.9 20.7 20.8 17.1 16.9 34.2 48.7 16.2 23.1 21.9 17.0 16.0 20.4 39.8 17.0 23.0 23.5 21.7 23.3 15.6 18.9 19.0 19.1 14.7 20.9 25.2 19.2 17.7 19.0 10.7 17.9 20.9 20.6 14.7 18.4 19.1 16.7 15.1 25.8 15.1 23.9 24.2 22.5 20.3 20.9 14.0 10.9 8.1 29.0 23.3 21.2 22.0 18.4 24.9 22.8 15.3 36.4 18.1 15.3 26.9 9.7 21.8 22.3 20.3 28.7 17.0 14.3 17.4 15.0 14.0 16.6 28.1 21.9 16.8 20.8 21.2 9.2 14.0 17.4 9.0 18.5 18.2 23.5 9.8 17.0 8.4 21.0 13.9 14.6 14.8 19.4 22.4 22.0 20.3 11.4 13.5 20.3 45.3 27.3 17.6 16.7 77.7 17.3 22.5 16.5 20.9 26.7 11.2 30.0 15.8 24.7 19.8 23.8 15.1 20.0 13.6 17.9 23.9 21.5 15.1 19.1 18.9 25.8 11.6 17.0 22.5 11.8 24.2 22.7 16.9 22.3 20.3 17.6 19.6 10.7 21.3 17.1 16.9 21.9 17.0 23.5 17.9 35.7 23.7 17.1 19.8 28.4 5.7 18.7 50.9 49.5 28.4 69.8 0.0 33.1 26.6 47.9 2.1 31.5 34.1 0.0 31.7 32.0 28.1 33.2 20.7 56.7 30.7 9.5 26.5 20.3 28.9 0.5 26.4 29.6 23.6 31.5 26.3 29.0 37.5 25.9 30.8 33.7 6.3 0.0 21.5 7.0 5.5 23.7 32.6 17.5 28.0 19.9 ZRANB1 TRABID ENSG00000019995 "Zinc finger RANBP2-type containing 1" Q9UGI0 10 124942123-124988189 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029239, HPA029240, HPA029241" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA029239: AB_10599419, HPA029240: AB_10601450, HPA029241: AB_10602205" "unprognostic (2.06e-1)" "unprognostic (5.16e-2)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" "unprognostic (9.53e-3)" "unprognostic (4.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (4.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.47e-2)" 5.1 9.3 4.9 1.9 4.7 7.9 5.3 11.9 6.0 6.3 5.2 1.4 5.9 5.2 4.1 4.4 3.6 7.3 4.6 4.0 4.2 10.4 4.2 2.5 4.4 8.6 3.1 7.1 3.9 3.9 4.6 3.3 3.4 5.8 18.0 5.2 3.0 6.3 3.8 2.8 3.6 7.7 3.8 3.9 4.2 4.8 3.4 1.4 4.6 1.1 3.8 4.4 0.8 7.7 4.4 9.5 6.9 14.8 12.5 4.0 7.6 20.8 14.5 16.9 6.6 6.1 8.1 5.7 9.6 4.7 5.6 12.0 5.6 19.6 8.6 5.9 4.6 5.1 7.1 31.6 6.9 3.5 13.8 16.5 10.6 22.8 20.3 9.1 7.5 0.6 6.7 7.8 6.1 8.1 6.0 3.4 4.2 4.8 7.0 6.7 3.6 6.4 5.6 4.8 8.1 6.4 5.0 8.4 9.3 5.5 5.9 6.7 6.2 6.4 5.1 9.4 7.2 6.2 9.4 7.0 4.9 3.0 2.1 1.1 3.0 2.2 0.4 1.9 2.4 2.6 2.2 0.9 3.4 4.4 3.3 4.6 3.8 0.5 1.4 2.2 0.8 17.9 25.9 5.7 19.6 21.9 32.7 21.0 15.3 21.4 19.4 17.4 47.1 10.6 0.0 11.6 60.8 18.8 11.6 0.0 10.0 8.1 20.6 26.5 25.4 38.0 10.6 35.0 25.7 15.4 16.8 27.1 22.2 19.1 15.1 8.2 15.7 23.9 15.7 8.2 21.5 8.7 24.5 12.9 24.7 23.3 19.0 24.3 23.0 17.5 10.5 20.0