Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC, WNT signaling pathway regulator" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.9" "Cell type enhanced" "Detected in many" 8 "Bipolar cells: 169.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 7.2 5.4 40.9 6.4 21.7 8.5 6.3 19.1 39.7 6.8 7.1 10.3 2.0 6.6 6.3 3.9 8.4 5.0 5.5 7.4 37.9 12.9 6.9 6.2 6.7 5.6 23.6 20.7 7.6 4.6 13.8 7.2 5.5 39.1 5.9 6.9 4.0 4.0 4.9 7.0 6.1 8.8 8.1 19.1 6.2 5.4 5.3 20.6 3.6 6.5 2.7 6.2 6.2 3.9 3.8 3.0 12.9 2.9 3.0 3.4 1.1 8.3 7.7 12.9 9.4 10.6 8.9 5.3 13.6 6.5 7.6 9.0 6.1 6.8 16.2 13.2 17.3 11.7 6.9 13.2 11.1 12.5 9.7 9.0 12.3 11.2 4.7 5.2 6.2 6.7 7.4 7.7 12.8 8.5 5.3 10.5 7.8 15.1 5.6 10.9 5.8 7.1 3.1 4.6 4.6 2.8 6.0 16.0 7.9 7.0 10.7 13.1 7.9 12.9 5.0 5.5 5.5 7.0 5.1 16.7 15.4 7.4 15.1 10.3 4.4 6.6 6.4 8.5 11.5 8.6 10.4 2.9 5.0 3.4 1.4 2.9 3.1 1.8 2.1 2.3 3.8 2.9 2.8 12.9 3.0 2.5 3.0 1.6 1.1 40.9 21.7 19.1 31.4 37.9 12.9 23.6 20.7 39.1 20.6 47.6 17.6 10.8 8.3 10.0 169.9 48.4 12.7 20.1 26.1 0.0 62.8 4.4 0.0 16.7 6.3 21.0 24.6 0.0 17.0 5.3 10.2 10.3 18.5 12.1 13.8 74.7 26.4 28.8 14.9 4.4 16.4 14.8 16.9 19.0 15.5 21.8 16.3 25.9 18.4 4.2 37.9 38.8 14.3 14.9 26.7 10.2 2.4 10.7 14.2 7.6 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "neutrophil: 19.6;NK-cell: 5.8" "Group enriched" "Detected in many" 4 "granulocytes: 19.6;NK-cells: 5.8" "Cell line enhanced" "Detected in many" "Karpas-707: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 13.3 5.7 18.4 18.6 22.7 33.9 13.0 29.2 23.9 15.9 14.2 7.5 9.9 13.2 9.4 10.9 7.6 18.5 16.4 17.0 12.8 10.5 8.0 7.7 20.0 8.8 12.9 15.4 4.8 5.5 4.8 15.1 22.4 11.9 8.5 14.8 8.8 14.6 11.2 14.0 8.5 12.6 11.1 12.6 18.9 17.0 16.1 12.2 10.3 10.0 5.4 13.6 9.4 10.6 0.3 2.0 19.6 2.8 5.8 3.0 1.0 6.9 14.0 3.9 3.6 5.8 6.4 6.0 0.8 1.2 3.4 5.9 19.1 15.8 1.0 6.9 2.2 10.3 3.3 1.9 6.6 4.2 14.3 2.2 0.0 1.8 12.1 3.7 10.2 1.4 2.3 11.6 6.2 14.3 2.7 5.0 4.8 0.2 39.7 1.0 1.1 5.8 4.2 1.8 10.3 3.6 2.2 5.8 16.6 9.9 10.7 1.5 2.4 1.8 1.9 3.2 3.1 1.0 3.1 9.6 1.8 2.6 0.2 3.6 1.8 5.7 0.2 4.8 9.7 2.5 2.9 2.8 1.6 3.0 1.7 1.3 0.2 0.6 1.8 2.0 0.3 0.2 0.8 19.6 5.8 1.0 0.5 0.2 1.0 18.4 22.7 29.2 23.9 12.8 10.5 12.9 15.4 11.9 12.2 14.9 22.7 2.9 13.9 6.2 9.5 33.7 25.5 12.0 12.5 0.0 7.9 1.1 0.0 15.6 62.7 31.7 30.5 0.0 18.9 0.7 11.6 26.2 25.5 4.3 21.6 71.5 3.5 30.1 49.8 105.1 6.1 31.8 10.1 6.4 26.2 6.3 16.0 21.5 13.4 4.4 54.5 45.3 12.7 1.9 11.3 4.8 1.6 22.7 21.7 31.9 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782110 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 18.6 18.4 17.4 24.9 17.0 33.8 27.8 23.6 19.1 20.3 23.7 21.7 23.9 15.8 24.1 17.3 23.2 20.6 21.9 15.5 14.8 12.8 13.7 15.9 18.8 35.6 20.3 19.2 24.1 23.9 27.5 15.8 19.3 17.2 16.5 16.4 18.9 21.4 23.1 22.6 20.6 20.7 18.4 15.4 25.9 19.5 16.5 19.8 57.3 24.8 14.2 24.5 24.4 20.4 4.3 5.3 7.4 3.3 4.7 5.1 3.5 19.2 18.3 25.9 27.0 7.5 7.2 12.2 9.0 7.9 12.4 8.8 13.3 13.0 27.2 7.9 11.7 7.8 11.7 22.5 10.0 14.5 33.6 8.8 23.1 11.9 8.9 6.2 34.2 7.4 8.3 7.1 14.6 10.5 6.9 10.6 19.7 27.6 30.5 8.0 9.1 28.8 13.3 27.4 12.5 8.5 30.1 17.1 15.4 7.7 13.0 24.3 20.0 15.8 13.4 10.9 15.0 3.9 19.4 18.7 13.3 12.9 12.4 14.6 14.5 19.1 12.5 8.1 21.9 11.7 0.4 3.3 2.9 4.0 2.9 5.1 4.3 3.2 4.9 3.1 4.3 4.0 4.4 7.4 4.7 2.8 5.3 1.5 3.5 17.4 17.0 23.6 19.1 14.8 12.8 20.3 19.2 17.2 19.8 56.6 36.8 33.6 18.1 65.3 60.2 31.1 28.1 25.4 28.4 36.6 49.1 31.8 1.7 31.8 14.2 37.2 28.4 0.0 32.5 32.1 42.6 39.3 56.9 53.9 43.0 69.9 45.7 51.0 93.5 7.5 35.6 45.4 38.8 34.3 56.1 31.2 40.3 31.6 39.3 14.5 37.1 51.8 27.2 46.0 55.3 82.4 30.7 41.2 46.0 27.7 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729665-45908040 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 522.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 9.0 7.9 7.1 14.6 7.2 14.0 11.8 15.7 8.8 10.2 11.4 8.2 17.9 6.4 12.2 10.7 11.5 8.8 10.6 8.2 7.4 5.8 8.7 6.9 10.2 13.0 9.6 3.8 12.2 10.7 18.4 15.1 10.3 7.5 9.9 8.1 10.1 9.7 20.6 8.6 13.5 12.6 12.5 7.3 10.2 9.0 30.9 11.0 33.3 11.5 8.2 11.2 10.0 10.0 2.1 5.3 10.5 4.9 3.1 4.4 1.3 5.4 7.8 14.0 6.1 6.0 4.2 7.6 3.8 5.4 5.3 5.0 11.1 5.6 10.5 7.1 5.2 3.9 6.6 11.3 6.5 7.7 4.6 5.4 13.9 8.6 5.4 4.1 10.9 6.4 3.4 4.9 6.7 10.8 7.5 5.4 15.9 11.7 10.9 4.7 7.1 15.6 7.8 8.4 0.0 4.2 12.1 10.0 10.1 5.1 9.1 7.6 9.7 6.2 7.2 6.0 8.4 11.0 21.9 6.4 5.7 6.9 3.8 4.9 7.3 6.1 29.4 4.4 28.8 4.0 10.5 1.7 4.2 4.1 2.2 4.3 1.7 3.7 4.4 2.4 2.1 3.6 3.3 2.4 3.1 4.9 5.3 3.1 1.3 7.1 7.2 15.7 8.8 7.4 5.8 9.6 3.8 7.5 11.0 26.8 27.9 10.2 11.5 30.0 49.0 12.6 5.1 9.4 12.5 27.9 64.8 11.9 6.6 11.2 522.0 21.5 15.0 0.0 8.7 8.9 17.5 17.9 20.9 13.1 9.9 30.2 20.2 16.5 27.5 122.6 23.0 20.0 13.5 12.6 19.9 19.7 15.6 24.6 21.2 6.9 67.9 25.8 22.7 61.7 16.5 36.1 19.6 24.5 16.0 16.5 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 198.3;Rod photoreceptor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.7 3.9 7.7 4.1 10.0 14.6 2.0 6.1 6.8 3.5 5.9 4.8 6.5 9.6 9.1 4.9 5.6 4.1 5.8 5.1 5.5 7.7 3.4 8.7 4.8 4.8 5.3 10.5 9.4 9.4 3.2 5.4 10.4 7.7 7.4 8.2 8.4 6.6 6.9 2.0 7.1 9.7 6.3 4.1 3.9 5.6 5.3 15.1 4.0 5.5 5.2 6.4 7.1 3.3 10.5 7.1 5.0 5.9 11.5 8.8 4.9 5.0 5.7 4.4 4.6 48.5 5.8 11.5 9.8 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 35.7 21.0 122.7 17.4 11.2 101.7 35.4 10.2 13.4 19.4 21.0 198.3 14.8 5.0 7.7 12.8 18.8 4.9 0.0 10.6 10.5 26.4 9.5 12.7 21.2 26.0 57.2 19.5 36.8 82.2 2.7 36.5 48.1 25.3 9.0 15.9 35.9 7.6 10.5 26.2 10.3 196.6 25.8 17.3 18.7 33.6 10.8 3.5 111.7 11.7 9.9 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352673 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 10.8 8.3 13.7 18.9 17.1 28.1 21.0 26.4 13.6 10.4 15.8 12.7 9.4 17.3 12.6 8.5 14.1 10.7 12.7 11.0 11.5 7.7 9.8 9.6 13.6 13.4 15.6 10.6 13.3 17.7 11.1 11.9 8.4 13.9 11.4 10.2 9.6 13.9 9.5 17.7 16.9 17.6 18.9 9.6 15.1 15.2 9.6 14.6 17.5 12.7 7.5 14.5 11.9 22.9 1.8 1.4 5.5 1.1 3.6 10.4 2.4 9.6 14.0 7.5 13.2 5.6 5.2 15.8 6.5 6.0 9.1 7.8 20.6 11.3 15.0 10.1 6.7 10.9 13.9 11.7 10.2 4.1 14.7 19.2 9.7 11.8 14.9 9.6 11.1 10.8 5.1 17.8 9.3 11.5 8.0 6.0 11.0 24.1 8.3 4.1 25.8 12.0 7.7 17.1 11.7 8.6 22.7 6.8 20.8 6.8 5.7 17.1 10.5 12.4 13.9 20.5 5.9 9.2 14.2 6.7 9.0 9.7 10.3 9.4 9.6 9.3 18.3 4.3 7.4 8.8 1.4 1.1 5.5 10.4 0.9 9.5 1.8 3.0 7.0 0.8 1.6 3.2 4.3 3.2 3.6 0.7 1.4 3.0 2.4 13.7 17.1 26.4 13.6 11.5 7.7 15.6 10.6 13.9 14.6 3.0 11.3 5.2 5.3 16.4 4.9 5.0 5.1 6.7 6.8 3.5 0.0 3.1 0.0 6.1 1.0 6.7 18.6 0.0 6.1 20.3 5.9 9.4 10.4 4.7 6.5 4.8 10.4 4.3 7.5 1.3 4.9 5.9 10.1 3.6 14.5 3.7 8.8 11.9 4.6 2.1 5.4 12.9 5.3 4.4 7.6 13.2 3.1 7.7 11.8 8.7 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401013-52410350 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850" "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favorable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 13.8 17.6 35.6 14.7 33.3 37.3 13.5 21.8 50.4 12.5 17.0 16.3 11.5 12.4 14.7 14.6 21.2 12.1 15.7 16.4 41.5 15.5 16.6 19.0 14.9 15.2 19.4 27.6 16.9 16.3 30.0 11.1 14.8 19.6 14.4 14.9 15.6 17.9 14.6 24.8 40.5 13.9 14.5 10.0 16.1 13.3 37.3 14.7 18.6 15.3 12.9 16.0 14.1 11.7 5.5 8.4 11.3 5.0 3.0 8.5 3.9 14.8 16.9 20.6 17.4 19.9 12.8 23.2 14.7 19.1 24.0 18.6 20.5 13.9 21.4 7.4 20.5 27.1 12.1 21.6 23.8 15.3 21.1 20.5 26.4 35.8 21.2 18.5 24.8 23.5 19.1 31.9 26.5 14.2 13.2 19.1 41.2 22.6 18.9 18.0 12.9 29.4 34.0 23.2 11.8 20.6 12.7 16.7 21.1 14.8 24.1 7.8 25.3 18.1 5.3 21.5 12.1 14.8 34.3 20.4 21.7 20.0 26.0 27.3 28.7 37.7 30.6 23.7 26.2 25.6 3.4 5.0 7.4 8.5 3.9 4.0 5.0 6.8 6.9 3.3 5.5 4.9 6.4 11.3 3.0 3.1 8.4 6.0 3.9 35.6 33.3 21.8 50.4 41.5 15.5 19.4 27.6 19.6 14.7 0.0 13.6 15.0 8.8 28.0 15.3 19.3 10.2 5.3 9.1 24.4 0.0 12.2 10.0 12.0 81.1 12.4 17.6 0.0 14.3 13.1 11.8 9.7 20.7 25.8 11.0 9.5 10.4 15.4 19.3 32.6 9.5 10.2 11.8 11.8 12.9 9.9 12.6 15.3 11.0 14.6 11.3 19.4 13.2 30.9 12.4 20.6 10.1 11.3 16.4 8.5 BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease mutation, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm NA NA Nucleoplasm "HPA056308: AB_2683095, HPA073591: AB_2732227" "unprognostic (2.75e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.55e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.30e-5)" "unprognostic (3.82e-3)" "unprognostic (6.86e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.91e-3)" "unprognostic (6.83e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-1)" 9.1 12.8 8.7 8.7 10.5 20.6 13.3 11.5 12.0 10.0 12.6 22.7 11.9 7.8 11.1 13.9 13.6 10.4 8.6 13.0 7.1 5.4 11.2 13.3 11.4 15.2 12.9 8.4 19.8 13.6 19.7 11.9 12.5 10.7 13.2 8.2 13.7 11.1 16.5 28.8 13.6 10.3 12.9 8.6 11.4 11.5 9.8 15.8 18.4 16.0 11.4 13.5 13.8 25.5 6.5 7.3 7.6 7.1 8.2 6.8 11.8 13.1 8.7 17.8 21.7 2.0 1.6 3.1 4.5 7.1 5.7 4.7 3.7 5.3 12.0 5.3 8.3 3.7 12.4 29.0 3.8 5.1 20.9 26.4 13.4 13.4 14.4 3.4 10.8 7.7 2.6 5.6 6.3 3.6 8.4 7.7 7.9 34.3 29.0 7.0 8.4 24.4 22.6 17.5 6.2 13.6 11.9 18.4 13.5 10.5 8.3 12.8 23.1 9.4 8.3 7.0 9.1 8.9 23.8 6.4 6.2 7.8 9.1 5.0 17.2 13.3 12.5 5.4 9.9 9.5 7.6 5.0 4.5 6.8 6.1 4.3 6.5 4.7 3.9 7.3 5.5 4.7 4.8 1.1 8.2 7.1 3.1 5.5 11.8 8.7 10.5 11.5 12.0 7.1 5.4 12.9 8.4 10.7 15.8 20.8 23.2 12.3 3.2 13.1 34.2 7.6 10.2 6.7 5.7 10.4 11.8 3.7 1.7 4.5 2.1 17.4 4.9 0.0 9.1 5.5 13.6 7.9 23.2 9.5 6.4 14.3 15.6 19.0 11.0 2.1 9.8 8.6 5.0 7.2 11.7 7.7 6.6 0.0 7.4 4.0 22.0 0.0 26.4 1.1 13.5 12.2 1.7 7.5 7.6 2.6 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1, DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Spermatocytes: 64.7;Spermatogonia: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 4.8 4.3 6.0 9.6 11.3 15.3 5.1 12.9 10.6 5.4 9.2 3.4 6.8 4.3 5.4 5.5 9.1 5.5 3.3 6.5 6.6 5.3 4.2 7.7 4.9 13.0 7.5 5.9 5.1 4.7 4.2 11.0 5.3 10.5 4.1 10.4 3.7 5.4 7.4 7.3 8.3 6.7 5.5 9.2 5.9 5.1 17.6 7.0 10.9 15.6 7.3 14.6 5.5 5.6 2.0 9.1 9.7 12.7 1.4 1.3 10.7 15.7 25.6 14.1 11.2 2.3 5.2 13.8 18.6 8.0 15.6 14.9 15.5 12.3 36.4 3.4 7.1 18.5 18.3 19.1 10.4 26.2 16.6 14.0 17.1 20.1 13.4 0.5 30.5 14.9 1.4 1.7 23.5 7.5 4.0 8.1 17.0 25.8 15.6 14.7 10.5 25.5 10.1 7.7 10.6 6.8 17.6 29.7 14.9 5.8 15.3 9.7 10.4 14.3 4.7 7.0 10.0 12.6 14.1 5.2 14.0 11.4 18.1 19.3 7.3 17.8 28.0 11.3 18.1 14.6 4.6 12.7 1.8 1.3 4.0 1.3 1.1 1.3 1.0 9.1 2.0 1.2 1.3 9.7 1.4 1.5 1.4 0.4 10.7 6.0 11.3 12.9 10.6 6.6 5.3 7.5 5.9 10.5 7.0 0.0 3.2 5.2 3.8 2.6 8.3 10.4 7.6 13.4 5.7 1.8 21.6 7.0 0.0 2.6 11.1 2.9 1.0 0.0 1.0 17.5 2.9 2.4 8.1 16.1 8.6 11.1 0.0 5.5 4.0 5.2 2.3 5.3 0.0 3.6 3.7 2.8 1.6 3.1 1.4 0.8 21.1 6.5 1.4 64.7 61.1 1.9 3.3 2.5 3.5 2.5 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2, DNA repair associated" P51587 13 32315474-32400266 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 16.9" "Group enriched" "Detected in many" 4 "Erythroid cells: 23.3;monocytes: 31.5;Spermatocytes: 75.1;Spermatogonia: 82.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 2.4 1.0 0.6 13.8 0.6 11.6 3.2 0.6 0.6 1.8 4.0 0.2 0.2 1.4 1.5 2.7 3.0 1.0 0.7 2.1 0.6 0.7 1.0 1.4 3.5 5.3 0.7 0.5 1.4 3.3 0.4 0.7 7.0 0.8 0.9 2.0 0.1 1.8 0.3 3.3 1.8 3.2 0.8 2.1 6.6 1.5 16.9 0.1 23.2 0.9 4.8 4.2 1.3 1.7 1.3 1.9 0.4 0.2 1.5 0.8 0.0 4.0 3.5 6.1 4.6 0.6 1.6 6.2 4.3 2.7 5.0 4.6 8.3 5.3 14.2 2.9 2.1 6.9 5.4 5.0 2.5 9.7 9.2 2.7 9.0 2.2 3.2 0.2 12.8 4.5 0.4 0.3 9.2 6.4 0.5 4.1 7.2 5.9 4.9 5.7 4.6 10.3 7.6 7.2 4.6 1.9 10.1 15.7 2.7 1.3 4.3 2.3 4.4 5.2 2.3 2.1 2.2 2.7 6.4 3.2 5.8 6.2 6.4 6.0 1.9 2.9 7.3 3.0 5.1 5.5 0.1 0.2 0.2 0.3 0.2 0.1 0.9 0.4 0.2 0.2 1.3 0.6 0.8 0.4 1.5 0.2 1.9 0.4 0.0 0.6 0.6 0.6 0.6 0.6 0.7 0.7 0.5 0.8 0.1 8.9 1.6 1.9 2.8 2.3 0.0 1.6 0.0 4.0 2.3 0.0 0.0 9.1 0.0 1.8 4.3 3.6 1.0 23.3 1.4 9.1 3.5 0.6 3.5 0.8 8.2 0.0 1.2 2.5 6.7 2.5 2.0 13.2 3.3 31.5 3.0 0.2 1.1 1.5 1.1 0.6 0.0 12.9 2.0 75.1 82.4 1.1 4.6 3.8 5.3 1.4 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Group enriched" "Detected in many" 7 "Spermatocytes: 66.9;Spermatogonia: 28.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA008419 Supported Cytosol Yes Yes Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.8 11.1 35.5 14.1 0.9 2.5 11.5 20.8 11.7 22.3 19.4 16.2 8.4 19.8 11.7 7.5 20.5 24.7 33.5 11.3 24.3 17.0 18.0 28.9 28.7 15.0 0.0 26.1 15.9 0.5 0.6 13.6 12.8 4.4 16.1 22.9 24.9 21.1 22.2 7.4 20.4 15.9 24.0 18.4 12.7 21.9 29.2 15.0 6.8 11.1 23.2 14.3 12.8 12.3 4.5 16.2 14.3 13.5 9.3 17.1 18.1 17.0 18.4 11.1 18.8 32.4 9.1 29.3 22.2 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 3.0 1.4 0.8 0.3 0.7 0.4 0.4 0.0 0.0 3.4 0.0 0.0 1.3 0.0 0.3 2.5 0.0 0.3 0.0 0.0 5.1 0.4 0.2 0.0 0.2 4.3 0.0 0.0 1.3 0.6 2.4 1.4 1.5 0.0 0.0 1.4 0.0 0.8 0.8 0.4 0.0 0.1 6.5 0.0 66.9 28.8 0.3 0.7 0.8 1.7 0.4 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 52.5" "Cell type enhanced" "Detected in many" 5 "T-cells: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol No No Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535" "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favorable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 14.1 10.6 2.0 31.6 2.6 27.1 10.2 1.4 1.8 7.9 18.5 3.9 7.0 9.6 9.6 12.0 11.7 9.1 12.1 4.4 2.1 2.3 16.4 14.8 17.1 28.3 3.9 1.1 8.2 7.6 1.8 5.9 12.3 3.2 9.8 8.7 4.4 9.6 8.4 2.7 7.4 34.7 5.1 5.0 37.7 7.4 3.8 2.7 43.7 6.7 10.7 43.4 9.6 7.3 13.8 13.7 52.5 17.0 22.2 26.4 12.0 14.5 12.4 3.6 10.1 10.1 14.8 5.6 6.4 6.3 7.6 12.6 16.6 25.4 1.6 14.1 4.9 13.7 7.4 7.9 7.6 15.1 9.4 7.2 14.2 10.1 15.8 8.2 11.0 15.4 12.8 18.8 14.4 11.3 6.4 7.2 12.3 12.7 31.6 6.9 6.0 14.3 11.6 5.9 8.0 11.1 10.8 7.5 25.9 14.3 16.2 1.1 0.5 8.3 13.8 8.2 3.5 3.6 8.6 9.0 8.2 8.6 4.3 5.0 28.7 12.8 9.9 12.3 14.8 7.7 20.7 13.0 24.9 25.0 17.0 23.1 13.8 20.5 26.4 13.7 7.8 13.3 16.9 52.5 22.2 15.6 6.1 24.0 12.0 2.0 2.6 1.4 1.8 2.1 2.3 3.9 1.1 3.2 2.7 23.8 26.1 34.1 10.1 6.6 1.5 1.6 7.6 16.0 18.2 5.2 9.8 7.5 13.3 9.0 5.6 7.1 19.8 0.0 7.3 10.3 3.8 8.1 23.2 10.4 11.2 0.0 4.1 5.5 25.6 0.7 2.3 21.7 6.8 19.8 13.0 0.1 9.6 12.7 0.7 20.0 0.4 0.0 1.4 0.7 0.4 6.8 2.9 55.4 12.1 12.7 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206276-119313926 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported Cytosol NA NA Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 9.9 5.5 9.1 17.0 11.1 11.1 8.8 10.7 12.0 6.2 7.5 8.7 3.0 5.7 9.9 5.3 7.5 7.4 6.3 5.9 8.0 9.6 5.5 4.0 10.3 16.3 8.1 6.9 6.3 5.6 16.6 4.1 9.1 9.3 5.3 7.5 6.4 5.4 7.1 3.9 7.4 8.6 10.6 8.9 13.3 7.3 32.3 5.1 40.9 6.0 5.5 15.6 7.6 7.7 1.8 3.3 11.8 3.7 0.6 1.9 1.0 6.3 4.8 16.9 10.6 5.1 6.0 10.0 6.9 7.2 6.7 6.6 10.3 7.9 15.1 6.2 8.7 13.8 9.3 11.6 5.9 14.7 8.6 2.7 15.5 3.7 3.1 6.2 18.0 17.7 5.3 6.5 17.0 18.4 7.1 16.5 14.8 12.5 6.3 12.0 6.9 9.6 10.1 8.8 5.7 5.4 10.4 8.5 2.8 5.9 5.1 2.3 7.1 12.8 5.6 4.6 12.1 5.8 15.2 13.7 10.4 7.4 7.2 9.0 2.1 3.1 12.3 4.2 15.6 7.4 0.8 3.2 2.4 1.3 3.7 1.1 1.8 1.6 1.3 3.3 1.8 1.8 1.9 11.8 0.6 3.1 1.8 1.4 1.0 9.1 11.1 10.7 12.0 8.0 9.6 8.1 6.9 9.3 5.1 8.9 8.8 18.8 4.9 16.0 12.4 5.9 7.6 1.4 4.5 10.4 43.2 5.2 1.7 5.8 22.7 17.8 6.3 0.0 5.8 8.0 8.0 6.2 3.5 2.6 15.0 12.7 8.1 19.0 52.9 32.8 7.2 29.9 15.1 5.4 4.3 17.5 8.7 8.6 12.0 3.1 33.8 25.8 17.6 38.1 26.2 19.2 5.8 20.0 4.5 9.5 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 38.4 9.0 3.7 19.5 4.9 15.5 16.3 24.4 3.8 13.7 18.7 5.9 7.7 9.3 13.8 12.2 8.3 12.5 13.4 27.5 3.8 4.8 7.4 6.7 16.3 19.1 4.4 1.9 17.7 6.8 3.4 13.5 25.4 7.9 12.9 8.0 11.6 9.1 6.3 10.3 8.5 13.8 25.6 5.7 16.4 12.4 9.2 5.2 11.6 13.5 7.0 18.0 24.9 24.1 5.1 3.1 2.8 2.1 10.3 9.9 1.6 1.6 2.3 7.7 3.8 8.9 9.0 5.0 5.8 2.9 1.7 2.7 2.9 2.0 3.6 4.0 3.0 2.7 2.9 1.0 1.0 2.1 2.8 2.9 2.0 12.0 1.9 13.1 1.4 1.5 8.6 3.1 4.5 12.3 6.4 5.6 3.7 2.1 11.7 3.6 2.1 2.0 0.9 2.7 2.0 3.3 4.2 2.3 0.6 4.1 7.4 6.0 6.5 6.8 0.8 8.9 5.6 1.7 2.9 3.1 23.9 2.0 3.2 1.4 6.6 0.6 5.7 6.4 1.2 1.5 0.7 1.5 2.8 9.9 0.9 8.8 2.2 5.1 5.6 1.3 5.1 4.4 8.0 1.0 10.3 2.1 3.1 5.6 1.6 3.7 4.9 24.4 3.8 3.8 4.8 4.4 1.9 7.9 5.2 14.9 6.7 21.6 6.8 9.6 44.8 39.9 0.0 10.7 6.8 12.2 25.5 8.9 5.0 6.0 27.4 22.6 8.7 0.0 6.9 53.5 21.6 9.6 8.1 6.7 12.2 3.2 12.1 39.3 11.3 9.0 6.9 10.4 15.1 5.4 16.2 7.4 11.7 7.0 10.3 3.1 27.4 6.5 19.9 9.8 15.8 6.0 38.0 52.3 10.7 3.0 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877120-41881372 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "blood: 125.3;intestine: 43.5;lymphoid tissue: 119.2" "Cell type enriched" "Detected in some" 6 "B-cells: 739.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "memory B-cell: 106.4;naive B-cell: 125.3" "Lineage enriched" "Detected in many" 41 "B-cells: 125.3" "Group enriched" "Detected in some" 24 "Daudi: 159.2;REH: 49.5;U-698: 138.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB000019 Enhanced NA NA "CAB000019: AB_2244527" "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 1.3 0.6 0.5 103.8 0.5 5.4 1.3 0.5 0.5 1.8 6.3 0.1 0.1 4.9 0.6 0.2 4.4 1.0 2.3 0.8 0.5 0.5 2.3 0.9 4.3 114.9 0.5 0.1 0.6 0.6 0.0 0.5 0.5 0.1 1.0 3.4 1.8 13.6 1.2 0.5 0.5 43.5 0.2 0.5 108.1 9.7 0.8 0.1 32.0 2.4 1.9 119.2 6.8 1.0 125.3 3.0 0.7 0.3 0.2 2.3 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 159.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 49.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.8 0.1 138.6 0.0 4.7 0.0 0.7 0.1 0.5 0.1 0.1 0.0 106.4 0.3 0.1 0.2 125.3 0.4 2.3 0.4 0.2 0.3 3.0 0.8 4.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.1 0.1 0.1 0.0 3.7 739.3 0.4 1.5 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.0 22.3 0.2 0.6 0.2 0.0 0.0 0.8 0.0 0.0 1.8 3.1 0.0 0.3 1.7 131.6 2.8 0.3 0.0 105.8 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.6 1.3 0.1 6.5 0.6 0.1 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932354 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 138.8;lymphoid tissue: 56.6" "Cell type enriched" "Detected in many" 8 "B-cells: 486.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 100.6;naive B-cell: 138.8" "Lineage enriched" "Detected in many" 6 "B-cells: 138.8" "Cell line enhanced" "Detected in some" "Daudi: 117.7;REH: 38.7;U-698: 161.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 1.7 0.7 0.4 50.6 0.4 11.1 1.2 0.3 0.4 0.6 1.7 0.3 0.3 0.7 0.6 0.5 2.6 0.6 1.4 3.4 0.4 0.2 2.3 1.7 1.3 56.6 0.4 0.3 0.6 1.6 0.0 9.0 0.5 0.3 1.0 1.3 0.8 8.9 0.9 1.2 0.9 22.4 0.5 0.4 56.0 1.8 0.6 0.3 3.7 1.4 1.7 46.6 4.5 0.9 138.8 4.2 0.5 25.0 3.4 9.2 9.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 6.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 38.7 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 1.8 0.1 0.0 0.4 0.0 0.0 5.9 5.7 161.1 0.0 0.2 0.0 0.5 1.1 0.0 4.2 16.5 4.8 100.6 5.4 2.8 4.2 138.8 3.7 2.2 0.5 3.4 25.0 0.6 9.2 9.0 0.4 0.4 0.3 0.4 0.4 0.2 0.4 0.3 0.3 0.3 0.0 2.2 486.9 0.3 3.9 0.0 0.8 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 7.1 0.0 23.3 0.0 0.4 4.3 0.3 15.0 0.5 4.7 0.0 1.2 62.0 14.1 1.1 1.1 3.5 20.3 1.0 0.0 0.0 0.0 0.0 1.8 0.8 0.0 0.0 3.3 0.7 0.1 2.8 0.3 34.6 0.0 0.1 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737225-68835548 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 125.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "myeloid DC: 2.8;plasmacytoid DC: 8.5" "Lineage enriched" "Detected in single" 18 "dendritic cells: 8.5" "Cell line enhanced" "Detected in some" "BEWO: 107.1;CACO-2: 36.0;CAPAN-2: 50.3;HaCaT: 48.6;hTCEpi: 34.3;MCF7: 29.7;OE19: 31.7;RT4: 37.0;T-47d: 32.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 22000000 "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.1 0.7 1.3 14.8 1.5 0.5 15.3 0.8 1.1 14.4 63.8 1.8 42.4 25.5 4.7 18.6 48.5 9.7 48.9 0.8 1.5 1.0 24.2 64.9 24.4 0.5 1.8 0.9 5.6 71.5 62.2 13.2 55.2 2.8 28.9 25.9 11.8 66.6 43.7 0.8 30.5 125.5 1.5 1.1 3.5 21.6 2.1 1.8 11.7 83.0 26.2 32.6 16.8 21.7 0.0 8.5 0.0 0.0 0.3 0.4 0.1 21.6 2.2 0.0 0.0 0.0 0.0 107.1 0.0 0.0 0.0 0.0 36.0 50.3 0.0 0.4 0.0 0.0 48.6 0.0 24.1 0.0 4.2 0.6 0.0 0.1 7.7 0.0 0.0 0.2 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.1 0.8 31.7 0.1 0.0 0.0 0.3 8.8 37.0 1.3 0.1 0.2 0.0 9.1 15.2 32.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.8 0.0 0.0 0.0 0.0 0.3 0.0 8.5 0.1 0.1 1.3 1.5 0.8 1.1 1.5 1.0 1.8 0.9 2.8 1.8 122.1 58.7 0.9 101.9 83.6 0.0 0.8 152.8 73.6 64.8 155.3 0.0 97.3 1.7 107.7 0.0 1.2 202.1 0.0 98.3 22.3 4.1 170.0 1.1 44.7 10.1 0.0 83.2 0.6 1.5 0.0 0.3 6.3 50.6 5.4 180.9 0.0 193.9 160.9 0.4 3.3 0.0 0.0 4.7 0.0 0.1 114.9 42.2 0.0 125.1 204.2 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967753-21995301 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 22.6;pituitary gland: 39.3" "Cell type enhanced" "Detected in many" 13 "Early spermatids: 178.1;Late spermatids: 275.2;Pancreatic endocrine cells: 259.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 22.6" "Group enriched" "Detected in many" 8 "B-cells: 7.2;T-cells: 22.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 50.2;HEK 293: 56.9;HeLa: 53.2;SK-MEL-30: 53.1" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 5.4 8.6 2.9 4.5 3.9 1.8 5.3 1.7 3.1 1.2 2.5 4.4 0.1 1.2 1.2 1.9 6.3 3.0 2.6 0.7 1.7 1.0 0.9 1.2 3.0 3.0 3.6 1.6 1.5 1.5 8.5 39.3 6.7 5.0 1.9 1.1 1.2 2.4 2.9 0.9 1.3 3.7 1.0 3.0 8.9 6.0 13.0 1.9 3.9 1.4 3.0 14.0 2.7 1.5 7.2 0.2 0.8 1.8 0.4 22.6 2.2 2.1 0.0 0.3 14.1 0.1 0.1 6.1 2.3 0.0 19.7 35.1 3.5 50.2 7.2 32.3 1.6 0.0 6.0 5.9 36.5 15.9 31.0 56.9 0.0 53.2 2.3 1.5 3.6 3.0 3.8 0.0 19.8 11.0 42.3 2.0 0.0 0.0 33.0 18.0 0.1 0.3 0.0 0.4 4.0 29.3 0.0 13.4 26.5 4.0 0.0 33.1 2.3 38.2 6.3 53.1 1.7 7.5 0.1 6.6 0.1 0.4 0.0 0.1 14.7 8.3 29.5 0.0 9.5 0.1 0.8 1.3 0.2 6.2 0.6 9.7 7.2 8.0 11.0 0.2 7.0 0.5 4.7 0.4 0.4 1.8 0.0 22.6 2.2 2.9 3.9 1.7 3.1 1.7 1.0 3.6 1.6 5.0 1.9 0.0 0.0 1.5 0.7 1.5 0.2 4.0 0.0 14.7 1.2 10.4 0.0 20.9 0.0 32.4 178.1 2.2 6.9 0.0 22.9 52.3 3.6 10.0 4.6 0.0 6.6 0.0 68.2 0.6 8.2 275.2 2.8 1.8 8.5 26.2 6.2 0.8 259.8 10.5 1.8 0.0 0.0 0.0 1.0 5.7 4.1 0.4 7.7 12.5 2.3 34.0 CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335" "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" 18.6 15.7 30.5 22.8 29.9 28.1 20.3 46.8 31.6 17.5 14.7 24.7 13.0 16.5 28.6 12.3 12.3 22.1 17.4 12.1 25.5 15.2 14.9 15.1 15.8 21.5 25.2 20.1 31.5 22.6 16.6 22.6 13.2 20.4 14.4 6.2 19.0 23.8 20.8 21.0 34.1 16.1 16.3 16.5 24.7 14.5 31.5 25.6 13.6 16.8 10.6 13.4 13.6 17.4 2.3 2.0 5.0 2.6 0.6 2.5 1.6 17.7 32.1 12.4 17.0 8.0 15.2 6.1 13.6 11.3 11.5 10.6 9.1 11.0 12.3 12.9 10.7 9.5 8.7 6.9 20.5 3.7 29.9 9.3 10.4 20.3 10.8 10.1 5.8 29.5 18.0 12.1 13.0 7.6 12.1 10.5 7.8 10.1 26.0 6.4 16.9 11.5 11.2 7.7 5.7 18.3 9.9 10.5 7.4 9.6 16.7 16.0 13.1 12.8 8.1 10.1 4.1 9.5 12.5 20.0 27.5 22.3 9.4 16.5 21.6 14.8 8.4 21.3 9.2 16.2 3.4 1.8 1.0 2.5 2.6 1.9 1.7 1.3 1.6 1.7 2.3 0.9 1.5 5.0 0.6 1.9 2.0 0.5 1.6 30.5 29.9 46.8 31.6 25.5 15.2 25.2 20.1 20.4 25.6 0.0 4.0 8.0 14.4 23.0 32.4 5.6 22.9 2.7 1.2 8.7 19.6 5.9 3.3 11.2 3.5 17.5 10.7 0.0 13.1 4.3 11.3 8.6 11.5 17.4 10.3 39.7 14.3 12.3 18.4 2.5 20.1 10.7 23.6 10.8 9.4 17.4 13.4 10.5 17.0 5.0 18.3 25.8 13.7 10.2 22.9 16.9 10.9 11.7 8.4 9.8 CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "non-classical monocyte: 21.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Nucleoplasm, Golgi apparatus" "HPA003277: AB_10601804, HPA003317: AB_2666891" "unprognostic (5.86e-2)" "unprognostic (5.39e-3)" "unprognostic (9.62e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-3)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "prognostic favorable (5.72e-7)" "unprognostic (1.12e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.97e-1)" 19.3 12.7 22.9 19.2 24.4 19.5 12.3 48.6 29.9 31.6 26.4 23.1 17.3 22.2 52.1 17.4 23.9 24.5 23.2 53.8 18.8 18.3 27.4 16.0 22.0 11.8 20.4 11.7 33.0 41.4 34.4 30.2 24.4 16.9 22.8 17.2 26.8 26.3 16.9 31.0 15.9 25.3 27.5 31.6 15.0 23.4 8.3 17.1 44.0 33.5 23.2 24.1 31.8 21.9 2.0 12.1 4.7 21.0 3.0 2.2 4.5 14.5 15.6 11.0 13.7 9.0 18.6 6.9 14.7 15.6 6.2 4.1 9.3 9.4 18.9 23.6 14.5 11.5 12.0 7.0 11.8 3.7 9.0 7.8 6.6 11.6 7.7 23.9 8.5 3.6 12.9 24.1 4.8 10.9 17.9 8.0 12.2 15.3 16.0 5.8 30.0 27.8 10.5 4.5 22.5 16.4 18.4 9.2 22.3 10.2 16.7 10.2 30.3 12.8 32.2 12.5 9.6 6.3 10.3 11.9 26.3 17.8 19.8 8.3 10.5 4.9 40.8 24.3 7.9 18.3 2.1 8.6 1.5 2.1 8.8 2.2 2.0 1.6 2.2 7.0 1.7 1.6 2.2 4.7 3.0 21.0 12.1 1.5 4.5 22.9 24.4 48.6 29.9 18.8 18.3 20.4 11.7 16.9 17.1 92.3 45.5 28.3 27.6 23.4 53.5 101.2 28.1 46.8 45.5 38.4 64.8 44.1 8.3 29.7 7.2 31.1 49.5 0.0 20.8 48.4 40.9 44.0 11.5 30.9 29.9 50.9 40.8 32.5 70.3 7.4 38.3 36.4 16.9 25.2 44.2 49.6 28.5 54.3 57.3 53.1 57.1 25.8 24.5 12.0 13.8 37.9 73.6 20.8 37.2 42.8 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: AB_2681013" "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.3 2.9 3.4 3.8 5.4 7.8 3.1 13.8 20.2 14.4 8.5 2.4 4.4 10.7 5.0 13.5 15.7 3.6 4.0 8.4 21.5 47.2 6.1 5.3 5.2 2.0 10.7 5.3 25.3 8.5 6.8 17.4 18.2 13.7 5.8 7.6 2.2 9.4 20.1 1.4 5.2 7.7 3.6 2.9 4.9 4.7 6.9 10.3 4.7 3.2 4.4 3.3 11.7 4.0 3.4 5.4 4.0 6.7 6.5 24.7 5.6 8.6 5.6 24.8 23.5 12.0 18.1 6.0 5.2 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 41.7 25.6 39.6 48.8 106.7 75.4 32.7 25.5 12.0 19.4 17.4 88.4 5.4 5.0 18.3 32.8 37.9 13.4 46.7 16.5 3.8 37.2 52.3 78.5 22.1 19.0 63.5 29.9 21.5 32.3 24.7 23.6 47.1 70.9 34.3 10.3 22.6 15.2 18.7 19.8 10.3 49.3 6.5 34.4 52.6 13.8 135.9 3.4 73.4 12.0 56.3 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 500000 "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 23.8 32.6 18.5 29.3 31.2 53.4 20.4 25.7 29.7 20.1 51.4 57.5 46.0 32.1 20.4 16.8 29.9 19.7 27.0 35.0 20.8 18.0 38.5 25.1 39.2 28.2 48.3 18.0 17.9 32.2 19.5 20.0 32.3 32.2 24.0 42.5 24.5 24.7 37.7 46.6 40.6 50.8 18.6 43.1 37.6 48.2 23.3 36.4 39.1 23.5 21.1 41.5 35.7 31.5 3.4 11.1 8.6 9.8 10.1 5.8 4.6 35.0 29.0 21.3 16.9 22.0 21.5 27.3 23.5 22.3 34.8 29.6 28.9 23.2 25.5 42.3 25.3 16.6 30.8 29.0 25.5 29.2 31.2 23.0 48.9 25.9 32.3 27.1 26.8 46.4 22.1 19.7 26.6 25.1 21.2 33.8 26.3 39.3 43.9 21.4 42.5 37.3 25.6 24.2 41.6 35.2 37.9 23.1 28.7 22.9 52.9 30.7 20.1 26.8 23.0 16.8 24.8 18.4 32.0 30.6 38.3 13.0 53.7 31.0 36.4 37.1 23.5 28.6 41.1 18.9 3.0 4.5 8.6 5.6 8.2 5.1 3.4 4.2 5.8 5.3 3.1 2.4 4.1 8.5 10.1 9.8 11.1 4.8 4.6 18.5 31.2 25.7 29.7 20.8 18.0 48.3 18.0 32.2 36.4 29.8 21.1 33.5 15.2 20.6 26.5 23.8 15.3 5.3 18.2 48.8 21.6 21.9 43.1 30.7 37.5 27.5 130.4 0.0 27.6 96.1 18.2 17.4 18.5 18.7 42.3 41.3 20.7 20.3 22.9 75.8 15.5 40.5 18.6 50.5 92.3 16.0 35.8 87.7 26.2 31.5 27.7 25.8 19.8 8.0 13.3 27.6 26.5 39.9 56.9 19.7 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 119.8;Horizontal cells: 90.6;Rod photoreceptor cells: 144.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 25.7;REH: 25.4;SH-SY5Y: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 7.8 12.4 13.7 12.7 15.5 10.8 8.6 21.6 20.1 9.0 12.7 14.5 7.6 9.1 13.0 12.2 8.0 9.6 8.9 8.2 12.3 6.7 9.4 6.9 9.5 13.6 15.3 10.1 18.3 12.1 6.3 12.6 20.8 10.7 9.3 9.2 12.0 8.5 9.2 29.1 6.6 11.4 11.3 7.9 17.5 11.6 6.6 15.2 20.8 9.1 10.5 11.8 9.8 8.4 3.0 4.1 4.9 4.1 8.7 8.3 2.3 1.1 3.5 14.9 3.6 1.6 1.2 19.5 1.0 0.9 2.0 1.6 8.8 5.7 0.0 2.2 1.9 1.6 1.0 1.6 2.2 1.2 3.7 2.6 6.4 5.3 10.5 3.9 1.3 4.1 3.6 1.1 2.6 0.9 3.9 8.3 14.5 7.3 1.4 1.5 8.5 13.9 15.1 25.7 5.9 1.9 25.4 16.4 2.1 1.2 1.5 8.8 31.3 1.2 8.4 2.6 13.4 1.0 6.7 2.8 2.5 3.3 0.6 1.3 3.2 2.2 8.6 0.9 3.8 2.6 4.7 1.8 3.1 5.2 3.0 7.0 2.3 3.4 4.9 2.0 3.0 8.3 6.6 4.9 8.7 4.1 4.1 2.8 2.3 13.7 15.5 21.6 20.1 12.3 6.7 15.3 10.1 10.7 15.2 6.0 13.3 10.0 8.3 4.6 74.9 13.7 5.1 9.4 12.5 19.2 119.8 30.2 5.0 13.8 1.5 14.6 5.3 0.0 8.5 9.4 14.7 11.7 36.9 5.5 19.8 90.6 12.6 6.2 10.5 1.1 17.8 11.9 6.8 4.6 11.5 22.7 9.2 10.5 14.5 5.6 144.9 19.4 8.2 2.3 13.4 2.3 26.9 18.7 11.0 6.7 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 7.4 15.6 11.4 10.6 17.7 6.7 7.1 9.5 23.8 9.4 8.1 11.7 7.8 7.9 11.7 6.0 6.7 10.0 10.1 7.9 9.4 9.1 8.7 13.2 6.5 9.9 8.2 10.5 9.5 13.1 12.9 10.9 7.2 14.0 8.2 6.4 12.5 9.5 11.8 15.9 10.7 7.1 11.2 5.3 9.7 8.3 17.2 7.8 10.8 10.2 5.1 8.3 9.3 6.6 7.8 17.2 5.0 13.9 11.3 9.8 8.7 12.6 6.2 12.9 18.1 7.7 9.1 6.8 18.0 12.4 23.3 17.9 14.3 8.7 4.5 10.3 17.5 8.5 6.5 9.0 15.1 8.9 10.9 14.8 7.7 11.7 15.1 16.3 12.2 13.6 10.5 2.4 26.6 15.1 13.0 13.5 13.0 18.6 5.1 16.0 6.1 7.1 8.1 5.9 11.6 10.9 13.8 9.2 3.8 6.7 11.2 7.5 8.2 16.0 11.3 6.4 10.2 10.7 16.2 17.5 22.3 12.2 9.4 40.0 11.9 6.8 6.5 6.6 7.4 9.8 0.0 13.3 5.0 7.7 13.9 9.8 7.8 7.4 7.4 17.2 5.8 7.1 7.4 0.4 11.3 10.9 8.3 7.4 8.7 11.4 17.7 9.5 23.8 9.4 9.1 8.2 10.5 14.0 7.8 6.0 4.3 3.6 3.9 5.6 0.0 6.0 10.2 6.7 5.7 5.2 0.0 9.4 11.6 7.6 4.1 3.8 2.9 0.0 7.0 10.0 6.8 3.5 0.0 11.5 9.8 0.0 6.9 9.2 7.3 2.2 6.1 4.6 3.3 1.8 7.8 0.0 6.2 3.5 7.4 11.3 0.0 0.0 5.2 33.8 11.0 5.0 4.0 2.9 7.7 3.3 ERCC3 "BTF2, GTF2H, RAD25, TFIIH, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294176 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease mutation, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "CAB037153: AB_796181, HPA046077: AB_2679527" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavorable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 17.4 20.0 26.1 23.8 28.9 20.5 21.0 35.9 32.0 22.1 19.4 19.7 17.1 11.5 21.6 15.7 19.1 23.6 20.4 20.4 23.2 18.8 17.5 17.4 19.4 23.1 19.7 25.8 23.3 22.4 32.0 26.4 16.3 21.5 20.1 17.1 18.3 18.0 21.8 30.1 19.7 17.3 26.1 16.0 24.5 17.4 39.5 20.1 24.1 19.3 15.8 25.9 22.4 20.8 11.8 13.9 7.2 9.7 18.8 16.2 11.7 22.2 15.3 19.0 20.1 21.1 14.5 23.5 20.5 26.6 33.2 32.2 23.4 16.3 16.9 17.0 18.7 21.5 20.0 28.9 21.6 28.9 26.4 25.9 21.2 18.7 24.6 15.7 18.4 23.1 15.0 20.3 38.3 16.4 21.2 21.3 22.2 20.6 11.1 20.9 22.0 26.2 19.8 27.6 14.5 23.9 21.6 21.8 14.0 18.5 20.8 23.0 24.8 17.5 26.7 26.8 22.7 14.4 21.1 16.9 20.0 22.9 18.1 24.3 19.9 38.8 26.5 17.7 8.9 21.3 6.6 9.5 7.2 16.0 9.7 16.2 11.5 11.8 13.5 13.9 11.8 15.8 10.9 3.1 18.8 7.9 11.3 16.1 11.7 26.1 28.9 35.9 32.0 23.2 18.8 19.7 25.8 21.5 20.1 20.8 13.4 8.2 8.1 6.8 0.0 10.5 5.1 32.1 22.7 7.0 0.0 15.9 1.7 12.0 3.5 14.3 4.9 0.0 13.1 10.3 12.0 6.2 9.3 7.8 12.5 0.0 5.8 12.3 12.6 3.1 15.3 9.2 8.5 12.6 8.2 0.0 12.9 5.8 12.0 7.0 0.0 12.9 8.5 34.7 27.5 8.3 12.2 13.8 9.9 5.6 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111853 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 55.5;fHDF/TERT166: 56.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 9600000 "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 13.8 11.9 5.8 20.5 4.6 2.1 16.5 7.3 7.4 13.3 17.1 4.1 8.7 23.2 11.5 12.5 11.2 8.8 19.3 14.4 4.6 3.1 8.8 66.4 19.9 8.3 3.0 6.8 10.4 17.9 7.1 6.4 15.6 4.8 9.8 16.0 13.2 9.8 13.3 4.2 12.3 32.0 16.8 4.3 20.1 11.5 5.0 2.7 8.7 12.0 10.3 7.2 11.0 18.5 0.8 1.7 1.2 4.5 0.7 2.4 1.0 17.3 5.0 7.6 3.0 13.7 11.1 3.5 32.5 55.5 24.0 22.1 5.2 1.7 0.3 14.6 56.1 17.9 11.0 3.3 19.1 33.8 6.5 5.6 0.7 4.7 4.1 6.4 0.0 1.2 6.9 5.1 29.1 26.8 30.1 14.7 1.6 0.4 4.8 11.1 1.4 0.8 0.0 2.4 9.2 6.5 0.0 2.8 0.5 9.4 6.3 2.4 2.2 5.0 2.3 4.8 20.2 3.2 0.2 19.5 20.2 18.6 18.6 9.5 2.8 2.7 1.6 18.8 0.0 5.4 0.3 4.4 0.2 0.2 4.5 1.3 0.8 0.5 0.6 1.0 0.1 0.5 0.9 1.2 0.7 2.2 1.7 2.4 1.0 5.8 4.6 7.3 7.4 4.6 3.1 3.0 6.8 4.8 2.7 17.9 5.9 1.4 18.7 48.7 21.1 6.2 28.1 5.3 6.8 7.0 13.7 5.2 0.0 34.9 1.3 16.6 42.3 0.0 17.2 3.2 32.1 10.0 6.9 22.6 2.2 9.5 4.6 17.8 28.9 1.6 16.1 5.4 18.6 5.4 20.7 6.0 21.6 14.0 33.9 5.0 24.5 0.0 28.1 0.5 4.3 41.4 10.2 2.2 21.2 17.9 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095549-44245429 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" NA NA 20000000 "Golgi apparatus" "HPA078409: AB_2686884" "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 24.5 19.5 11.6 17.2 18.5 6.6 25.8 14.5 23.0 26.8 25.0 15.5 17.5 17.6 37.1 25.5 16.7 26.0 23.4 22.7 11.7 13.0 19.2 36.3 22.3 16.8 11.8 12.3 29.3 21.8 25.7 17.3 58.0 16.2 23.7 20.6 22.9 24.7 22.8 16.9 20.2 34.0 35.0 12.2 18.7 19.3 20.0 11.4 16.2 24.7 16.7 13.0 20.2 23.2 6.7 14.9 13.0 12.0 17.8 17.6 9.8 13.1 18.2 9.9 30.7 45.6 33.6 13.6 40.8 51.1 24.2 33.0 12.9 9.1 9.1 18.6 47.8 25.6 21.0 10.5 29.0 29.3 18.2 14.5 8.4 9.6 9.9 18.0 8.4 18.1 26.0 19.2 14.6 22.9 28.5 34.3 8.7 11.2 16.4 17.6 10.1 5.8 5.1 10.6 16.8 13.0 7.3 28.2 4.6 14.0 12.5 7.1 7.9 25.8 10.6 6.8 18.3 17.6 9.0 31.0 32.7 21.4 32.0 26.2 7.4 9.7 6.7 21.5 6.5 34.9 9.3 11.9 13.0 15.6 12.0 17.6 6.4 12.5 14.4 14.9 6.7 11.9 11.7 2.6 17.8 8.5 5.1 9.6 9.8 11.6 18.5 14.5 23.0 11.7 13.0 11.8 12.3 16.2 11.4 14.9 8.8 10.5 13.2 13.5 11.5 9.2 5.1 5.3 10.3 12.2 13.7 27.3 5.0 28.2 30.2 16.7 20.5 0.0 20.6 30.2 24.4 17.7 5.8 15.5 16.2 12.7 1.7 21.5 11.9 17.4 25.3 7.7 5.0 10.0 14.0 16.6 21.7 14.0 26.9 7.0 14.3 19.4 16.9 36.9 21.7 11.0 29.5 7.5 13.3 14.6 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "Fanconi anemia complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6;testis: 28.8" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 23.3;Spermatocytes: 22.3;Spermatogonia: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 2.1 2.0 2.2 16.5 3.7 17.1 1.7 5.7 6.6 1.7 5.1 1.1 0.6 5.0 1.7 3.1 6.6 1.9 1.6 1.7 1.8 1.4 2.1 5.8 3.3 11.1 1.3 2.7 1.6 1.8 2.3 1.9 11.2 2.4 1.7 6.3 1.5 2.2 0.5 0.7 5.0 5.4 2.0 1.6 6.9 3.5 28.8 0.8 20.6 1.7 4.6 17.6 2.9 2.5 7.4 6.5 9.9 9.2 7.5 9.5 4.2 9.3 14.4 17.3 15.1 1.1 2.2 13.2 11.7 6.4 19.8 8.3 12.6 15.6 23.1 5.5 4.0 6.6 14.5 11.6 8.7 20.9 5.4 19.5 6.8 18.5 25.8 0.7 6.9 7.5 0.7 0.9 16.0 5.1 2.8 6.2 11.7 16.3 7.1 10.3 21.7 13.8 30.0 11.2 12.9 9.0 25.2 13.9 4.2 4.9 8.9 15.5 8.4 17.5 5.2 2.2 10.4 9.4 12.5 4.6 15.9 16.8 8.8 12.2 6.4 7.5 22.9 7.5 15.5 15.1 2.6 7.9 9.9 4.7 8.8 3.3 7.4 2.8 4.1 6.5 5.5 0.7 3.0 9.8 7.5 9.2 0.4 9.5 4.2 2.2 3.7 5.7 6.6 1.8 1.4 1.3 2.7 2.4 0.8 0.0 0.6 13.1 1.4 3.1 8.8 1.6 0.0 1.4 3.4 15.7 9.8 10.9 1.7 1.6 5.3 0.8 2.0 23.3 1.4 7.5 1.3 0.5 2.3 4.0 7.7 3.2 1.7 7.4 4.3 3.5 1.4 6.3 0.0 0.0 6.1 1.4 1.5 0.0 0.0 6.8 7.2 0.0 1.0 22.3 33.2 1.6 21.2 3.2 6.3 2.1 FANCC "FA3, FAC, FACC" ENSG00000158169 "Fanconi anemia complementation group C" Q00597 9 95099054-95426796 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 29.7" "Group enriched" "Detected in many" 5 "Early spermatids: 190.4;Late spermatids: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 10.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.4" "Cell line enhanced" "Detected in all" "RH-30: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017793, HPA030771" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB017793: , HPA030771: AB_2673604" "unprognostic (1.48e-2)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-2)" "unprognostic (3.41e-3)" "unprognostic (1.26e-2)" "unprognostic (7.45e-3)" "unprognostic (1.37e-1)" "unprognostic (8.00e-3)" "unprognostic (3.19e-2)" "prognostic favorable (6.03e-6)" "unprognostic (2.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.71e-2)" 4.9 2.7 4.3 8.6 7.0 3.6 4.6 29.7 7.7 4.6 6.4 4.9 5.1 7.1 6.3 4.1 4.5 3.6 5.2 3.2 4.0 2.7 10.0 25.7 6.7 3.7 7.3 1.6 3.3 5.4 2.9 12.1 4.3 6.7 4.4 6.1 4.0 4.0 4.2 4.5 7.7 8.1 2.9 6.4 3.4 4.4 19.6 7.3 7.9 4.3 3.2 6.0 3.5 4.0 1.0 1.3 10.4 1.7 0.3 1.5 0.7 13.6 9.2 12.2 10.6 1.2 3.2 7.7 5.9 3.9 9.5 8.8 10.5 5.8 7.8 4.2 4.3 7.3 16.7 12.3 5.2 5.2 7.4 5.8 6.1 10.4 5.4 2.0 6.1 6.8 2.7 2.2 7.6 3.4 2.6 5.2 7.6 9.1 3.4 6.8 9.6 5.7 3.5 5.8 14.5 5.2 12.2 31.5 3.6 3.9 3.5 17.7 9.4 11.3 4.0 3.4 6.4 4.2 5.1 2.5 8.3 12.2 9.1 8.4 3.6 6.6 4.1 4.5 5.6 9.8 10.4 0.4 0.0 1.3 0.8 1.3 1.0 0.7 1.5 0.4 1.0 1.2 1.0 0.1 0.3 1.7 1.3 1.3 0.7 4.3 7.0 29.7 7.7 4.0 2.7 7.3 1.6 6.7 7.3 3.0 2.1 0.0 2.3 2.3 5.4 1.6 5.1 1.4 3.4 0.0 3.9 2.3 1.7 4.1 190.4 4.3 3.3 0.0 3.6 4.0 2.0 2.5 5.7 25.1 1.8 9.5 0.0 4.3 2.7 63.3 6.1 1.3 1.7 3.6 4.5 2.6 3.4 0.0 2.1 7.7 4.2 0.0 1.6 13.0 10.6 2.4 1.9 1.0 3.8 2.5 FANCE "FACE, FAE" ENSG00000112039 "Fanconi anemia complementation group E" Q9HB96 6 35452361-35467103 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 18 "Extravillous trophoblasts: 82.2;Syncytiotrophoblasts: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 7.2 2.1 2.6 7.0 3.8 7.2 8.5 5.5 3.9 6.7 4.1 4.8 1.5 3.1 6.1 4.7 10.0 4.9 5.4 4.1 2.8 3.2 2.4 1.7 5.5 5.4 2.4 1.8 10.8 6.9 2.7 4.0 21.3 3.9 6.7 4.1 3.7 5.3 4.0 20.8 16.8 4.7 4.1 3.7 4.6 3.8 12.1 3.5 3.0 5.9 10.1 8.5 6.7 15.0 2.4 1.8 1.0 1.0 2.6 3.6 0.9 5.7 2.8 7.9 17.6 5.7 10.2 21.1 6.9 5.9 9.1 7.9 6.7 3.3 19.6 4.6 4.3 6.9 4.3 8.8 5.9 8.8 6.6 7.6 13.7 6.9 4.3 3.1 8.0 5.6 6.4 17.8 11.1 17.1 2.4 5.3 7.6 12.6 7.3 7.6 6.7 3.7 10.0 3.2 6.2 4.5 11.1 7.5 7.4 2.0 6.3 7.8 7.3 4.0 5.6 6.2 7.6 5.5 26.3 3.2 11.0 9.2 7.0 10.8 4.9 16.9 7.1 2.4 14.8 10.3 0.7 1.0 1.0 2.2 0.6 3.0 0.7 2.8 3.6 0.6 2.4 1.9 1.9 0.6 2.6 0.6 1.8 1.7 0.9 2.6 3.8 5.5 3.9 2.8 3.2 2.4 1.8 3.9 3.5 6.0 0.0 0.8 3.9 7.8 0.5 1.7 0.0 0.0 1.2 0.0 0.0 17.8 0.0 1.2 0.2 2.5 0.9 0.0 0.7 82.2 3.8 2.4 0.0 0.0 5.2 0.0 1.2 1.8 1.2 0.0 1.4 1.3 1.7 0.0 2.9 1.5 1.0 0.0 0.7 0.2 1.7 0.0 2.5 6.9 10.4 6.1 39.0 1.0 3.3 2.7 FANCG "FAG, XRCC9" ENSG00000221829 "Fanconi anemia complementation group G" O15287 9 35073835-35080016 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Extravillous trophoblasts: 17.3;Spermatogonia: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 5.8 5.0 4.4 7.1 6.5 14.9 7.5 13.9 8.5 6.2 5.9 5.3 8.4 6.7 6.8 3.2 9.2 8.6 4.7 5.9 7.6 4.0 5.2 4.5 5.1 9.9 8.7 4.4 9.2 17.0 6.7 4.8 7.6 6.6 7.0 5.5 3.5 8.7 9.7 2.9 8.9 6.5 6.4 4.2 8.6 5.8 8.9 7.6 25.6 9.3 4.8 9.2 6.8 6.9 6.8 4.8 8.9 2.5 8.8 9.2 3.4 15.7 19.6 14.4 13.3 3.2 5.1 12.1 11.1 8.0 21.8 21.0 9.3 9.9 15.6 7.7 3.5 15.6 9.7 11.9 10.2 8.4 18.3 7.2 11.2 21.0 5.7 0.9 11.3 12.9 4.2 2.0 19.0 8.6 3.8 11.1 19.2 7.3 21.0 11.0 14.0 19.1 15.6 14.9 11.8 15.1 19.9 16.9 11.0 5.1 6.7 7.0 12.7 7.3 10.4 4.1 6.5 13.5 8.2 6.7 10.4 20.7 13.3 14.9 5.7 10.8 9.4 9.2 8.4 14.2 8.9 0.8 7.7 7.4 2.5 6.5 6.8 6.1 5.7 2.2 6.5 4.8 5.0 1.3 8.8 2.3 4.8 9.2 3.4 4.4 6.5 13.9 8.5 7.6 4.0 8.7 4.4 6.6 7.6 3.0 5.8 5.2 3.6 3.9 4.3 1.0 0.0 0.0 2.3 3.5 3.9 8.2 3.3 3.7 0.3 2.8 1.6 0.0 2.0 17.3 3.8 3.5 13.9 1.0 6.5 4.8 1.7 3.7 0.3 0.4 3.1 2.0 3.3 3.6 3.9 3.5 2.3 3.2 3.9 1.7 3.0 0.0 2.7 10.9 23.7 2.3 5.5 5.3 5.0 3.3 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587783-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.4" "Cell type enhanced" "Detected in many" 4 "Basal keratinocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.9;LHCN-M2: 47.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 120000 "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 15.5 1.3 7.9 12.3 9.8 0.4 15.4 11.9 8.4 15.9 40.4 11.8 8.1 17.9 20.6 14.0 9.7 9.6 28.2 21.1 10.0 6.0 29.1 13.3 10.9 1.4 11.4 6.2 9.7 13.8 7.5 10.5 14.6 24.7 15.9 22.9 5.0 13.9 18.2 3.0 13.1 76.4 18.3 12.8 1.7 11.5 7.0 11.2 1.3 10.5 10.2 6.7 17.5 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 19.0 18.9 0.0 18.9 22.8 4.6 25.4 41.9 12.4 7.9 11.3 11.2 0.0 6.1 64.9 8.0 9.2 7.4 31.3 16.9 0.0 3.0 0.0 6.7 11.4 9.4 8.2 6.8 8.2 11.3 23.0 15.0 17.0 0.2 10.3 0.1 0.0 47.7 6.0 14.6 0.0 4.2 9.5 3.2 0.0 5.2 0.4 18.6 17.9 2.0 7.6 4.4 7.5 3.0 13.5 0.0 3.0 5.4 35.4 13.7 0.4 15.7 0.1 0.0 0.1 8.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.8 11.9 8.4 10.0 6.0 11.4 6.2 24.7 11.2 14.9 4.1 0.0 25.5 75.6 5.2 20.3 35.7 16.0 25.0 50.6 0.0 1.1 5.0 21.9 0.6 5.1 58.5 0.0 23.2 3.5 24.9 37.8 16.1 22.9 0.3 0.0 13.9 1.8 1.0 0.4 13.6 3.1 11.8 0.0 54.8 4.2 24.0 23.0 35.0 21.4 0.3 38.8 54.6 1.8 7.7 40.9 1.4 0.0 38.7 20.0 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075203 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 97.8;skin 1: 61.7" "Cell type enhanced" "Detected in many" 19 "Cytotrophoblasts: 243.8;Extravillous trophoblasts: 651.3;Syncytiotrophoblasts: 949.1" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 42 "gdT-cell: 9.7;MAIT T-cell: 13.3;memory CD4 T-cell: 18.2;memory CD8 T-cell: 14.1;naive CD4 T-cell: 10.0;naive CD8 T-cell: 9.0;NK-cell: 16.6;T-reg: 18.9" "Group enriched" "Detected in many" 54 "NK-cells: 16.6;T-cells: 18.9" "Cell line enhanced" "Detected in some" "BEWO: 33.3;MCF7: 79.6;RT4: 32.6;SH-SY5Y: 28.0;T-47d: 103.7" "Region enriched" "Detected in single" 6 "midbrain: 7.3" "Group enriched" "Detected in some" 38 "midbrain: 25.5;pons and medulla: 17.5;thalamus: 20.0" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 2.0 2.0 0.3 3.4 0.3 0.9 17.8 0.3 0.3 1.8 0.5 0.1 44.4 0.1 0.4 13.5 0.8 0.4 0.4 0.9 0.3 0.4 12.9 0.7 1.6 2.7 0.8 0.0 0.3 0.4 55.0 3.8 53.4 1.4 8.1 0.0 1.8 8.9 97.8 0.8 61.7 1.2 3.4 0.4 2.7 0.5 0.8 0.1 42.4 3.3 0.6 3.4 26.9 16.4 0.2 0.0 0.3 0.0 16.6 18.9 3.0 5.5 1.3 0.0 0.0 0.0 0.0 33.3 0.1 0.0 0.0 0.0 2.0 5.0 0.0 0.0 0.0 0.0 4.9 0.5 0.1 0.0 16.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.3 0.1 2.6 7.8 0.0 0.0 0.0 79.6 8.7 0.0 0.6 1.0 0.7 0.4 0.4 0.1 0.0 32.6 1.6 28.0 0.0 4.5 0.0 6.1 103.7 0.0 0.0 0.4 1.0 0.2 0.7 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 9.7 0.0 13.3 0.2 18.2 14.1 0.0 0.0 10.0 9.0 0.3 16.6 0.0 0.0 18.9 3.0 0.3 0.3 0.3 0.3 0.3 0.4 0.8 0.0 1.4 0.1 0.0 8.9 0.5 60.9 84.1 0.0 1.2 0.0 0.0 1.2 169.3 0.0 243.8 0.0 0.2 0.0 4.9 0.0 0.0 0.3 651.3 6.9 27.0 2.3 0.5 27.7 0.0 0.0 9.8 4.0 0.0 0.0 2.2 8.5 1.0 0.0 0.0 2.6 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 173.9 949.1 56.1 0.0 68.0 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985895 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 262.7" "Cell type enhanced" "Detected in many" 10 "Fibroblasts: 127.3;Muller glia cells: 96.7;Syncytiotrophoblasts: 124.3" "Cancer enhanced" "Detected in all" "liver cancer: 269.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.0;naive CD8 T-cell: 3.5;NK-cell: 1.7" "Group enriched" "Detected in many" 12 "NK-cells: 1.7;T-cells: 5.0" "Group enriched" "Detected in some" 5 "HAP1: 54.2;Hep G2: 214.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 30.1 5.9 0.4 3.6 0.7 0.0 50.2 0.6 0.4 3.3 4.5 0.5 2.2 0.5 2.5 11.7 2.0 3.4 9.2 8.0 0.4 1.1 21.2 1.1 37.0 1.9 1.6 0.4 6.0 4.6 0.3 16.9 262.7 1.6 3.6 1.0 6.3 3.8 2.3 4.1 5.5 1.8 3.3 2.1 0.9 4.0 2.1 0.3 2.3 7.2 11.2 3.0 7.6 8.0 0.0 0.2 0.0 0.0 1.7 5.0 0.6 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 54.2 0.0 0.0 0.0 2.5 0.0 0.1 214.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 14.8 0.7 1.8 4.4 0.0 0.0 0.0 26.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.2 0.0 5.0 3.5 0.0 1.7 0.0 0.0 0.0 0.6 0.4 0.7 0.6 0.4 0.4 1.1 1.6 0.4 1.6 0.3 0.0 1.7 0.0 5.4 9.3 0.2 0.3 0.0 44.2 35.2 5.2 0.0 43.0 16.6 0.3 0.9 0.5 0.3 0.0 1.3 32.7 127.3 0.9 0.0 0.0 24.0 0.0 1.7 2.5 0.0 1.3 9.8 1.4 3.3 0.0 1.5 96.7 2.2 0.2 2.8 26.9 1.9 0.0 5.0 1.6 6.1 3.4 124.3 0.0 2.1 0.5 KDM5C "DXS1272E, JARID1C, MRX13, SMCX, XE169" ENSG00000126012 "Lysine demethylase 5C" P41229 X 53191321-53225422 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038244, HPA046147" Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA038244: AB_2675911, HPA046147: AB_2679555" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (1.56e-2)" "unprognostic (7.10e-2)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.08e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.45e-2)" "unprognostic (1.58e-2)" "unprognostic (5.05e-3)" "unprognostic (1.96e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" 19.5 22.9 22.4 22.6 24.7 26.3 17.9 43.0 31.7 25.9 19.5 23.4 16.7 22.2 29.2 13.3 26.9 24.8 15.2 17.6 21.6 15.3 17.0 18.8 20.6 25.8 24.6 21.8 33.1 22.5 37.7 31.8 34.0 22.8 18.7 13.5 17.0 25.6 17.1 36.6 28.4 22.2 23.6 16.0 25.0 19.4 10.6 26.2 29.0 22.2 11.3 24.5 21.5 26.4 4.5 4.3 4.8 4.0 2.8 6.1 3.8 16.9 23.1 24.8 19.0 17.2 15.7 17.6 10.6 12.4 14.4 13.4 15.6 11.1 15.8 13.8 13.9 40.6 15.2 28.0 22.7 11.0 11.8 41.4 15.3 24.7 11.0 21.2 18.1 30.6 12.4 16.7 28.1 34.7 20.6 21.2 13.2 29.7 10.5 10.5 21.7 13.2 20.4 21.0 8.8 21.7 15.0 14.8 17.1 9.1 16.3 18.7 24.1 32.2 29.9 12.1 23.8 20.9 16.0 14.5 16.1 13.9 14.4 10.3 15.3 12.4 12.0 20.9 21.5 11.9 3.0 3.8 2.7 6.1 3.6 5.1 4.5 3.7 5.7 3.1 3.2 4.5 2.9 4.8 2.8 4.0 4.3 4.3 3.8 22.4 24.7 43.0 31.7 21.6 15.3 24.6 21.8 22.8 26.2 11.9 12.2 11.9 9.7 10.8 25.0 7.7 17.8 12.0 12.5 7.0 23.6 10.6 3.3 13.4 0.6 14.3 21.7 0.0 18.7 11.4 11.3 12.4 12.7 19.8 12.4 23.8 30.0 18.4 14.6 1.7 13.6 9.4 13.5 10.0 27.8 10.9 20.8 24.6 14.9 4.2 16.1 0.0 10.3 7.0 14.6 13.9 17.4 10.2 15.6 15.9 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873177-45112602 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 12.3 12.1 16.5 17.6 24.5 47.9 21.4 26.1 22.0 16.9 11.8 16.7 12.0 13.1 22.6 11.3 15.4 16.9 15.2 9.1 18.2 6.5 11.6 13.5 19.7 15.1 28.8 11.3 23.8 14.9 21.3 20.2 13.3 18.3 10.3 11.3 10.3 16.1 12.6 15.1 21.3 17.6 13.5 14.9 18.1 15.0 17.7 26.1 19.1 14.5 6.9 13.6 14.9 22.8 5.5 7.1 15.7 7.5 6.2 7.9 3.5 8.7 7.6 11.3 11.4 8.1 8.4 24.2 6.8 4.8 8.2 8.6 17.9 7.5 5.7 3.7 6.3 17.0 18.8 14.5 12.0 7.6 8.3 15.5 7.1 9.6 6.7 5.7 3.8 20.2 4.5 9.9 13.5 14.1 8.8 6.3 7.0 9.8 14.2 5.1 5.7 7.8 11.2 9.4 6.7 8.8 8.7 10.9 1.0 4.7 16.3 9.7 5.2 21.7 10.9 9.2 24.8 10.6 0.1 5.3 7.8 6.0 7.8 3.5 9.0 10.8 8.6 5.4 4.0 4.5 15.7 3.8 3.5 5.3 7.5 6.0 5.5 7.2 7.9 7.1 3.8 7.0 6.3 7.3 6.2 7.2 3.8 5.6 3.5 16.5 24.5 26.1 22.0 18.2 6.5 28.8 11.3 18.3 26.1 6.0 8.8 5.2 11.3 23.2 6.5 11.4 10.2 5.3 7.9 7.0 13.7 3.8 0.0 6.5 1.0 9.4 18.8 0.0 6.6 4.9 8.9 11.4 2.3 13.9 6.1 23.8 12.6 6.2 8.9 1.1 6.1 9.7 10.1 7.2 14.2 7.4 7.7 14.4 6.7 3.3 8.4 6.5 10.3 5.6 11.7 23.1 9.2 10.1 11.0 16.3 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.5;THP-1: 25.7" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.6 4.0 6.3 4.2 1.0 0.8 10.6 1.3 1.7 4.0 5.6 18.7 5.0 5.9 0.4 1.5 3.4 3.4 5.2 2.3 5.6 2.0 2.3 3.3 1.8 8.8 2.5 5.2 9.2 1.0 2.5 1.2 2.0 1.1 1.7 2.0 2.8 10.7 1.0 2.9 3.6 7.1 2.9 3.4 0.5 5.7 4.4 20.3 7.0 6.9 2.6 27.5 3.9 4.9 11.2 5.8 13.4 25.7 5.0 0.4 3.4 1.5 2.4 7.8 4.0 11.3 0.6 3.1 6.8 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 6.0 9.8 47.7 14.5 46.5 15.2 2.7 50.9 4.0 12.5 34.9 45.2 12.9 6.6 14.2 1.6 13.5 6.6 0.0 12.8 7.7 11.3 11.9 7.0 12.1 26.3 27.0 9.8 17.2 81.7 1.9 4.9 40.3 35.4 45.9 10.1 10.6 13.0 7.0 1.8 20.1 34.7 6.5 5.2 10.0 15.0 47.8 5.6 16.6 8.9 10.0 MED12 "CAGH45, FGS1, HOPA, KIAA0192, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118556-71142454 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm NA NA Nucleoplasm "HPA003184: AB_1079349, HPA003185: AB_1079350" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.89e-3)" "unprognostic (7.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.16e-2)" 18.2 31.3 12.3 15.3 14.7 16.6 18.1 18.0 15.1 16.8 12.8 19.8 21.3 10.2 21.7 16.5 13.1 17.7 14.2 12.9 12.9 8.5 13.3 9.8 14.0 15.3 15.7 10.7 28.8 14.2 20.1 17.9 23.0 11.6 16.5 11.8 18.6 14.6 20.3 14.9 17.6 14.8 16.4 11.2 27.3 14.2 15.3 12.9 33.1 17.8 12.6 15.9 15.4 16.4 4.0 5.1 9.7 3.7 5.0 7.4 3.6 8.7 10.3 16.3 9.7 12.0 10.7 24.1 6.2 8.9 9.9 7.1 12.4 8.3 11.5 8.2 10.7 6.8 8.7 19.0 7.8 7.9 12.1 14.7 19.1 23.2 16.7 9.4 17.5 16.9 12.4 8.5 12.9 15.0 12.7 15.2 14.7 17.7 20.2 9.7 14.7 18.4 10.0 9.3 11.2 13.5 17.3 18.2 8.7 7.5 17.4 9.1 11.0 14.3 7.3 8.1 17.5 8.8 8.7 13.2 10.8 12.8 9.9 4.3 10.0 5.5 8.4 6.3 9.8 7.2 9.7 3.7 7.2 5.9 3.6 5.0 4.0 4.1 5.4 3.9 4.0 4.6 3.9 7.7 5.0 2.4 5.1 7.4 3.6 12.3 14.7 18.0 15.1 12.9 8.5 15.7 10.7 11.6 12.9 8.9 3.4 5.2 5.2 5.4 7.1 8.1 15.3 2.7 6.8 8.7 5.9 17.0 1.7 5.4 0.2 8.7 6.8 0.0 5.4 6.2 7.8 5.7 9.2 3.4 8.0 12.7 7.5 14.1 6.7 0.9 13.0 9.2 5.0 6.4 7.8 5.8 8.6 8.4 12.7 2.2 4.5 0.0 5.0 6.4 7.4 5.0 22.8 6.4 6.4 6.8 MEN1 ENSG00000133895 "Menin 1" O00255 11 64803510-64811294 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030342 Uncertain Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA030342: AB_10610138" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.66e-1)" "unprognostic (2.59e-1)" "unprognostic (1.42e-2)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.39e-2)" "prognostic favorable (6.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" 12.1 20.6 13.2 15.6 17.7 11.8 12.5 25.8 26.9 15.5 14.9 16.4 22.2 16.9 14.8 18.4 18.9 17.6 14.7 9.0 12.4 11.5 15.9 23.0 12.8 22.1 12.5 15.6 19.7 25.9 16.8 18.0 16.1 16.0 15.9 11.6 16.6 23.3 19.9 8.4 21.6 15.8 11.0 9.8 20.6 15.3 21.2 12.3 33.2 23.9 6.2 20.3 13.7 15.5 5.2 2.9 3.4 1.5 1.8 4.8 1.0 16.3 22.0 14.1 22.1 15.8 10.2 16.6 11.8 11.7 18.4 12.4 12.7 16.2 23.3 19.3 9.1 15.4 23.4 19.1 16.3 11.1 19.9 28.2 19.3 17.7 16.9 14.0 12.4 13.1 11.7 12.3 15.5 12.8 11.1 17.0 30.0 28.0 8.9 10.2 30.6 31.3 25.1 18.4 13.8 33.1 24.3 16.0 22.3 11.9 15.2 19.9 17.5 13.9 19.7 14.3 10.5 29.3 13.8 10.7 17.4 16.7 20.8 9.9 14.0 16.2 11.8 13.8 9.7 11.0 0.9 1.3 3.4 3.7 1.5 4.8 3.7 2.6 4.6 1.3 5.2 4.5 2.6 0.2 1.8 0.5 2.9 1.9 1.0 13.2 17.7 25.8 26.9 12.4 11.5 12.5 15.6 16.0 12.3 3.0 4.8 19.3 3.8 5.0 8.3 3.7 2.5 1.4 1.2 3.5 5.9 15.7 3.3 7.3 0.9 4.4 8.4 0.0 6.2 18.5 4.6 4.9 1.1 9.4 7.9 3.2 4.1 8.0 0.3 0.6 11.2 2.6 8.5 6.4 8.7 8.4 7.1 10.1 3.5 6.2 5.7 12.9 2.7 16.6 15.5 6.0 13.6 6.7 9.5 3.0 MLH1 "COCA2, FCC2, HNPCC, HNPCC2" ENSG00000076242 "MutL homolog 1" P40692 3 36993332-37050918 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348" "unprognostic (1.26e-2)" "unprognostic (3.88e-3)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (8.24e-5)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (8.63e-3)" "unprognostic (2.10e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (8.86e-2)" 16.3 20.7 18.2 19.4 21.4 24.4 18.7 19.7 19.6 15.3 17.3 28.8 19.6 12.4 18.7 23.6 15.1 16.2 14.4 32.0 17.3 17.7 18.8 20.5 17.8 22.8 19.9 16.0 17.6 18.1 26.0 29.4 17.3 19.2 18.5 17.7 16.7 15.6 18.1 46.4 14.2 14.1 21.1 21.6 20.7 16.5 27.6 21.5 29.0 22.2 19.5 24.5 16.9 21.4 12.0 12.9 13.2 23.2 6.7 13.4 9.0 14.2 22.5 28.1 0.0 12.5 15.7 12.6 21.3 17.0 24.8 26.4 17.0 15.9 35.3 10.6 17.3 14.0 9.8 24.2 18.0 26.6 16.0 12.5 24.7 20.8 23.8 13.9 30.3 17.2 11.7 12.7 23.1 28.8 9.8 15.3 23.9 31.6 16.9 25.1 11.5 31.6 12.4 20.6 14.5 12.4 3.1 34.4 14.9 15.7 15.5 6.0 14.2 21.6 23.0 14.2 16.4 33.2 21.6 12.1 19.5 21.0 19.1 25.0 13.4 36.6 33.1 15.1 28.7 17.5 10.9 11.7 13.2 13.4 19.5 9.7 12.0 8.4 10.7 12.9 10.3 9.6 9.7 3.4 6.7 23.2 6.1 12.5 9.0 18.2 21.4 19.7 19.6 17.3 17.7 19.9 16.0 19.2 21.5 23.8 12.0 16.0 10.7 6.4 19.2 37.1 15.3 16.0 13.6 10.4 9.8 27.1 16.6 12.5 20.3 11.2 5.3 0.0 13.0 23.0 13.4 8.0 7.0 14.5 17.5 3.2 5.2 12.3 14.3 9.5 10.3 11.4 8.5 19.8 7.2 14.3 8.6 7.0 13.1 9.2 17.9 12.9 9.5 37.0 25.4 4.8 16.7 13.1 7.6 3.4 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47402969-47663146 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatogonia: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 7.3 9.8 14.2 12.2 25.5 11.4 14.1 22.6 18.1 9.4 11.6 7.6 5.6 6.5 10.5 13.3 10.8 11.1 4.9 8.4 13.0 14.0 7.3 5.5 7.1 19.7 12.5 17.0 7.9 8.4 15.3 9.1 9.9 18.5 7.9 13.8 12.3 9.4 7.3 6.7 10.3 8.0 7.8 13.8 9.4 6.7 13.4 13.5 37.0 13.9 6.6 21.4 8.5 7.6 7.4 2.9 3.9 4.2 12.2 12.6 6.2 28.3 9.7 26.5 14.3 2.0 5.6 16.1 16.9 8.4 21.0 20.3 18.2 12.3 34.9 22.8 5.9 14.8 12.1 19.8 9.6 31.7 18.0 14.8 25.1 11.2 16.5 2.0 24.5 8.8 3.1 2.8 17.8 4.8 4.7 11.5 0.8 41.8 8.1 16.0 11.3 28.4 18.5 49.9 17.2 11.5 38.1 47.4 20.4 9.1 15.0 22.0 23.9 14.9 11.6 11.9 22.3 11.6 9.6 4.6 13.9 18.3 14.4 18.8 5.2 18.5 48.9 8.5 18.1 8.6 2.8 1.0 3.9 7.9 4.2 8.6 6.3 7.4 9.5 2.3 7.4 12.6 11.9 0.7 12.2 3.2 2.9 10.1 6.2 14.2 25.5 22.6 18.1 13.0 14.0 12.5 17.0 18.5 13.5 8.9 11.5 13.7 5.7 7.3 16.8 13.8 5.1 25.4 13.6 8.7 43.2 14.2 3.3 9.6 13.1 11.7 4.6 23.3 7.3 16.3 8.7 3.4 11.5 1.0 9.6 11.1 3.4 3.7 4.0 17.6 4.9 4.0 8.5 6.4 9.1 20.0 6.0 5.8 6.0 3.5 38.3 0.0 5.5 34.2 59.5 5.6 4.2 8.7 9.8 2.7 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810101 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 13.0 20.5 9.7 13.1 18.8 13.6 13.0 20.5 13.1 17.9 13.3 17.6 10.7 6.1 28.2 11.0 12.4 18.3 8.4 8.6 11.4 8.8 9.5 14.6 11.0 21.7 23.9 9.6 43.2 27.6 16.2 17.3 14.9 15.0 14.6 10.3 8.7 12.0 13.2 10.4 10.3 10.5 22.1 14.9 11.6 11.1 25.1 22.0 40.4 13.4 10.4 25.8 14.2 16.4 8.4 8.4 7.6 9.8 9.7 15.1 5.7 27.5 20.6 38.3 9.1 11.6 12.2 17.3 15.3 13.5 15.9 16.7 15.1 9.6 45.5 23.0 16.6 21.9 11.6 34.5 19.5 20.8 19.8 17.2 29.1 16.3 15.3 7.1 29.2 10.7 9.9 6.2 16.2 10.8 14.9 9.9 1.1 25.3 16.7 15.5 19.9 31.1 13.8 33.6 18.6 9.5 73.8 50.2 20.5 9.7 17.9 21.5 23.3 21.3 10.2 9.3 35.1 12.2 10.3 6.0 18.5 22.6 14.0 19.8 15.7 21.2 76.2 15.6 18.7 11.3 7.6 5.8 4.9 8.4 9.8 10.4 8.4 9.5 8.3 8.4 8.1 15.1 7.6 3.9 9.7 9.3 4.2 9.5 5.7 9.7 18.8 20.5 13.1 11.4 8.8 23.9 9.6 15.0 22.0 26.8 18.4 9.7 20.1 22.3 26.4 6.9 0.0 28.1 31.8 7.0 33.4 24.9 3.3 12.8 25.7 15.3 2.6 0.0 8.4 16.9 17.4 11.4 17.3 8.5 11.1 14.3 4.6 12.3 5.1 11.5 23.6 12.1 3.3 7.2 7.9 27.0 8.8 3.5 21.2 5.3 29.7 6.5 17.2 40.0 40.2 15.3 8.0 13.3 9.3 10.7 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 149.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 2.3;granulocytes: 6.5;T-cells: 8.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 12.9 15.9 22.6 13.3 25.9 5.5 18.5 30.2 26.0 17.6 13.6 19.8 12.2 11.0 16.9 17.0 10.5 15.2 13.1 17.3 21.6 19.6 20.0 15.1 12.7 11.5 19.4 25.6 22.9 16.5 34.1 19.0 19.4 20.9 16.1 14.7 12.1 14.4 20.5 14.8 12.0 12.1 14.5 21.4 11.9 13.0 15.4 21.5 11.6 31.1 7.6 12.4 15.3 19.5 2.3 0.7 6.5 0.4 0.9 8.4 1.0 9.8 12.9 15.7 8.4 13.4 17.5 7.9 8.6 15.5 12.7 14.4 11.6 6.7 9.5 2.5 16.0 15.0 17.3 14.2 12.0 21.5 4.6 8.9 8.4 12.1 5.9 9.5 15.0 7.0 13.8 7.7 13.5 16.5 14.4 6.1 10.1 12.0 9.5 12.1 7.8 12.5 5.5 4.6 6.1 4.3 9.8 24.0 7.6 9.6 14.2 6.5 9.8 15.9 5.3 8.8 11.6 16.2 9.6 8.9 10.2 14.2 12.0 3.2 8.7 4.2 10.5 8.3 6.3 10.5 6.5 0.4 0.9 2.3 0.2 1.6 2.3 4.4 3.9 0.5 2.1 3.3 3.2 1.0 0.9 0.4 0.7 8.4 1.0 22.6 25.9 30.2 23.5 21.6 19.6 19.4 25.6 20.9 21.5 29.8 23.6 12.7 38.9 34.3 61.1 39.2 40.8 29.4 20.5 38.4 129.6 44.8 19.9 23.9 149.0 31.8 28.2 0.0 19.3 22.1 28.2 47.4 10.4 31.7 18.9 66.7 19.0 31.9 24.3 70.0 34.5 21.8 20.3 16.2 26.8 49.7 28.6 35.4 47.4 23.7 66.0 45.3 36.7 28.2 25.6 29.6 41.2 18.5 22.6 60.1 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 61.9;Late spermatids: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 11.8 12.4 23.6 11.1 20.1 10.0 15.4 20.8 28.1 10.8 9.7 9.0 11.8 7.8 10.5 11.3 14.2 11.3 8.0 19.7 26.6 16.4 13.5 11.1 11.9 24.1 18.0 13.5 11.0 12.9 46.8 8.6 6.9 11.4 10.2 8.7 9.5 9.3 15.4 25.7 12.1 8.5 11.9 10.7 10.4 8.8 21.6 10.1 14.9 15.6 11.5 9.9 10.6 10.2 8.5 13.6 6.6 17.3 11.6 15.0 9.8 26.6 10.8 3.8 24.6 7.4 7.4 3.6 21.7 12.2 23.8 20.6 10.6 6.6 7.1 18.0 22.3 16.5 9.5 7.8 12.6 21.3 10.3 6.1 8.4 8.1 7.6 7.9 12.0 10.0 6.8 5.7 16.9 20.6 8.1 16.7 4.6 4.1 6.6 23.1 11.2 7.3 4.8 2.8 6.3 10.2 7.6 20.3 6.8 24.2 12.5 5.8 4.0 12.4 8.4 4.9 4.0 5.4 4.8 31.0 35.5 40.5 15.4 36.6 10.3 8.2 8.5 9.4 4.7 22.6 6.6 9.5 3.6 15.0 13.5 12.8 8.2 11.3 10.1 13.6 8.5 9.8 9.2 2.3 11.6 17.3 9.3 9.4 9.8 23.6 20.1 20.8 28.1 26.6 16.4 18.0 13.5 11.4 10.1 6.0 16.1 9.0 9.6 12.6 16.5 19.9 17.8 6.7 7.9 14.0 9.8 9.9 18.3 42.9 61.9 9.8 8.4 0.0 21.5 6.3 12.6 9.5 23.0 12.5 12.4 28.6 12.6 10.4 10.0 86.8 6.6 7.2 8.5 6.4 7.5 17.3 28.7 15.6 11.7 16.2 8.5 6.5 14.9 21.4 7.2 12.5 3.2 10.9 9.8 8.6 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833275-37034185 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 21.6;lymphoid tissue: 33.4" "Cell type enriched" "Detected in some" 27 "B-cells: 57.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "midbrain: 1.6" "Group enriched" "Detected in some" 209 "memory B-cell: 20.1;naive B-cell: 21.6" "Lineage enriched" "Detected in single" 216 "B-cells: 21.6" "Group enriched" "Detected in some" 8 "Daudi: 21.5;REH: 62.5;U-698: 28.2" "Region enriched" "Detected in single" 11 "midbrain: 4.7" "Group enriched" "Detected in some" 6 "hippocampal formation: 3.8;midbrain: 10.8;pons and medulla: 3.2" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA Nucleoplasm "Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.4 0.2 0.2 33.4 0.2 5.5 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.4 0.2 0.2 0.3 0.5 0.3 0.3 23.2 1.6 0.0 0.2 0.2 0.0 0.5 0.1 0.2 0.3 0.3 0.4 2.5 0.0 0.6 0.2 8.7 0.0 0.3 16.5 0.7 0.9 0.0 2.3 0.4 0.2 30.1 1.3 0.2 21.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.1 0.1 62.5 0.1 0.1 0.0 0.0 4.4 1.0 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 1.6 0.0 0.2 0.0 0.0 0.0 57.6 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 PBRM1 "BAF180, PB1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA015629: AB_1855012, HPA059373: AB_2683994" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" 24.3 14.8 13.8 20.6 15.9 17.2 24.4 19.1 13.8 18.9 18.5 14.0 22.9 12.2 25.9 13.9 19.9 18.9 13.7 15.9 11.1 10.0 11.7 14.5 14.9 16.5 16.5 8.2 25.1 15.4 14.4 30.6 28.0 14.7 16.1 15.3 12.7 17.5 16.2 21.8 17.2 14.3 21.1 15.6 19.1 14.8 13.1 13.7 51.0 22.0 10.5 17.1 22.4 23.0 6.6 10.7 11.1 8.7 4.6 7.4 1.9 12.5 8.1 29.0 14.2 14.3 14.6 20.3 17.3 11.9 20.0 17.6 9.1 8.5 30.4 2.4 20.3 16.6 8.6 25.1 13.1 24.4 32.5 13.5 28.8 15.3 7.0 20.5 24.0 21.9 13.6 15.2 22.4 14.5 15.8 19.3 24.1 16.4 16.7 20.1 4.2 39.5 7.2 17.6 8.5 13.3 20.7 18.2 15.5 8.3 24.5 19.7 21.8 20.8 5.0 16.5 18.4 9.4 13.9 22.2 18.8 14.3 16.2 21.1 12.1 19.0 28.9 11.6 19.5 18.7 10.1 5.0 11.1 4.8 3.2 4.9 3.6 4.8 5.3 4.8 6.6 7.4 4.7 2.7 4.6 8.7 10.7 4.5 1.9 13.8 15.9 19.1 13.8 11.1 10.0 16.5 8.2 14.7 13.7 38.7 54.1 19.5 31.0 35.9 42.0 48.4 28.1 53.5 38.7 22.7 45.2 31.3 16.6 31.4 28.7 40.3 25.3 23.3 40.4 28.9 31.5 35.3 27.8 37.0 45.9 28.6 33.8 35.0 63.3 14.7 31.7 46.6 45.5 50.5 30.6 28.5 42.9 28.1 54.8 13.9 43.3 25.8 45.3 41.9 32.8 45.0 42.6 34.1 34.5 33.3 PHF6 "BFLS, BORJ, CENP-31, KIAA1823, MGC14797" ENSG00000156531 "PHD finger protein 6" Q8IWS0 X 134373253-134428791 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease mutation, Epilepsy, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001023 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA001023: AB_1079606" "unprognostic (2.38e-3)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (3.04e-3)" "unprognostic (6.03e-3)" "unprognostic (5.20e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (1.09e-1)" "unprognostic (5.96e-2)" "unprognostic (4.84e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" 7.4 19.3 10.2 14.1 12.2 6.5 9.7 18.2 13.5 8.7 8.0 11.6 20.3 7.8 9.0 30.1 11.5 7.3 6.1 7.2 11.0 11.1 9.9 7.5 8.4 20.4 12.5 9.3 30.7 10.4 24.1 18.1 8.2 13.3 8.6 9.5 5.4 11.3 16.8 6.2 7.4 10.2 8.1 17.1 17.8 8.1 8.3 14.4 30.2 11.8 6.0 25.0 8.9 9.8 18.4 11.0 5.3 7.4 9.6 9.9 5.0 11.5 9.6 42.3 17.3 7.9 10.1 8.0 11.6 9.3 12.5 15.5 5.7 12.0 18.6 26.7 7.0 12.2 10.4 29.5 13.1 21.1 15.1 13.7 18.0 16.5 6.6 8.4 17.9 10.0 6.7 10.0 13.6 17.0 12.6 17.4 18.2 13.2 9.2 15.3 7.6 28.9 8.9 12.9 15.8 13.0 28.5 15.4 14.1 13.3 14.0 14.7 17.2 8.9 8.2 12.2 13.1 7.7 9.9 13.2 11.7 8.4 14.6 17.8 4.7 10.9 25.1 7.6 21.4 14.5 5.3 6.1 3.7 7.9 6.0 8.5 18.4 8.2 7.1 8.8 12.8 9.9 8.2 2.5 9.6 7.4 11.0 8.3 5.0 10.2 12.2 18.2 13.5 11.0 11.1 12.5 9.3 13.3 14.4 20.8 17.3 24.1 12.5 11.6 21.9 13.7 7.6 16.0 13.6 15.7 17.7 9.9 19.9 12.5 2.6 14.3 7.9 0.0 11.8 6.8 11.3 10.2 23.2 12.7 13.2 17.5 10.9 19.6 12.6 2.1 19.2 15.3 6.8 19.0 13.4 25.6 12.4 15.0 14.5 16.5 18.2 25.8 9.2 4.6 17.9 10.0 3.9 22.0 16.6 11.0 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 106086320-106109939 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.9" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 49.1;T-cells: 100.2;Urothelial cells: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "eosinophil: 5.6;gdT-cell: 12.6;MAIT T-cell: 19.3;memory CD4 T-cell: 12.0;memory CD8 T-cell: 11.6;naive CD8 T-cell: 6.8;neutrophil: 6.8;T-reg: 15.4" "Group enriched" "Detected in many" 5 "granulocytes: 6.8;T-cells: 19.3" "Cell line enhanced" "Detected in some" "Karpas-707: 68.5;RPMI-8226: 12.8;U-266/70: 25.7;U-266/84: 16.6" "Region enriched" "Detected in single" 6 "olfactory region: 4.4" "Low region specificity" "Detected in all" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 11.6 1.5 1.6 26.3 3.2 10.4 7.0 5.3 1.6 14.0 16.5 1.9 1.4 5.4 11.6 2.2 33.4 3.8 8.1 2.3 1.9 2.0 3.1 2.4 18.8 33.3 2.1 0.5 4.2 1.8 1.2 2.1 9.0 4.9 3.6 11.0 4.3 10.6 3.0 2.0 8.9 18.2 3.4 7.4 24.2 8.6 3.0 1.5 3.1 7.7 35.7 49.9 12.8 18.0 1.5 0.2 6.8 0.6 2.5 19.3 1.3 0.4 0.1 0.3 0.0 0.5 0.7 0.0 2.3 7.2 0.7 1.3 0.4 2.8 0.6 0.1 4.6 0.1 0.1 0.0 1.1 0.8 6.4 0.0 0.1 1.4 0.0 1.1 0.2 0.5 0.7 3.6 1.0 3.0 0.2 0.9 0.3 0.4 68.5 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.0 12.8 0.6 0.1 0.0 0.0 0.3 0.3 0.0 0.5 0.3 0.7 0.4 1.1 0.6 0.6 2.1 25.7 16.6 1.5 1.6 0.4 0.6 1.2 0.4 5.6 12.6 0.6 19.3 1.5 12.0 11.6 0.2 0.5 1.1 6.8 6.8 2.5 0.1 0.2 15.4 1.3 1.6 3.2 5.3 1.6 1.9 2.0 2.1 0.5 4.9 1.5 0.0 9.0 19.7 8.0 17.3 0.8 1.4 0.0 2.7 7.9 3.5 49.1 0.4 0.0 0.3 0.8 20.4 7.3 23.3 0.2 0.5 5.1 3.1 3.5 1.5 19.3 0.0 1.7 8.0 24.7 0.0 0.0 38.5 35.4 47.7 3.1 0.5 4.8 4.3 1.1 0.1 0.4 0.0 16.4 0.3 1.3 36.3 0.6 100.2 2.5 77.0 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Cardiomyocytes: 608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 11000000 Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 47.1 48.0 41.7 34.5 54.8 14.6 38.7 40.4 57.4 48.2 23.8 44.9 31.4 15.1 43.6 37.7 29.6 43.2 37.4 122.7 42.5 52.3 49.2 43.4 47.3 29.5 50.1 43.6 62.5 19.1 107.8 41.9 47.3 57.7 35.6 24.2 32.2 47.5 43.6 99.8 22.8 19.3 39.4 52.8 35.3 25.1 36.9 40.1 28.2 51.8 23.6 29.2 33.8 33.4 11.3 26.9 52.6 28.7 18.5 13.0 22.9 16.6 32.1 41.2 24.6 55.0 62.5 6.2 22.5 46.5 35.2 31.2 12.5 22.5 16.9 15.5 49.1 36.1 13.8 30.4 36.5 50.6 11.4 10.9 26.2 27.9 40.8 39.9 20.0 29.4 44.6 38.0 40.6 34.3 39.6 58.4 14.5 11.8 26.7 42.6 31.6 22.0 10.7 15.2 17.2 21.9 15.4 68.2 18.7 53.4 36.3 15.0 20.3 20.6 37.7 86.7 40.0 29.5 28.3 41.4 49.7 23.7 22.4 20.9 22.3 15.8 25.2 30.1 19.1 30.9 31.1 26.1 46.3 13.0 25.5 13.0 11.3 9.8 11.6 26.9 8.5 8.9 9.8 52.6 18.5 28.7 8.8 12.3 22.9 41.7 54.8 40.4 57.4 42.5 52.3 50.1 43.6 57.7 40.1 137.0 210.8 75.1 77.8 126.8 93.4 608.0 89.2 258.3 168.4 239.0 62.8 66.4 150.9 74.2 287.1 138.4 34.9 23.3 45.5 74.3 135.4 82.7 180.2 101.7 123.8 131.9 131.3 160.2 157.1 53.4 123.7 102.2 182.2 93.8 51.5 115.8 62.1 52.9 179.3 150.9 56.6 84.1 208.1 100.7 40.5 115.2 69.0 106.6 36.6 95.0 PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease mutation, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 17 "Late spermatids: 165.3;Leydig cells: 176.9;Peritubular cells: 417.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 8.9" "Lineage enriched" "Detected in many" 8 "T-cells: 8.9" "Cell line enhanced" "Detected in many" "NTERA-2: 15.8;WM-115: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" 4.1 3.8 6.7 6.0 9.5 0.7 7.9 21.0 6.4 28.5 12.5 6.1 8.0 7.8 16.2 4.2 3.0 7.4 13.2 2.8 7.0 6.6 4.9 2.2 7.1 4.5 9.5 3.2 5.2 10.8 3.4 4.0 3.7 6.9 6.9 12.3 11.2 6.9 9.5 2.7 4.3 10.9 8.5 5.1 3.8 12.1 14.3 7.9 1.0 6.3 1.9 3.2 11.3 6.9 1.0 0.0 0.0 0.0 0.3 8.9 1.8 5.1 2.5 10.9 6.8 1.6 2.7 6.2 1.0 0.9 1.2 0.7 2.5 2.5 4.1 1.8 1.9 2.3 11.8 6.2 0.8 0.7 4.0 4.1 0.0 2.5 1.1 1.5 0.1 2.3 2.5 1.3 1.1 0.8 2.3 2.2 1.8 3.6 4.8 0.5 1.0 0.0 1.6 15.8 3.7 1.0 0.0 8.3 2.1 0.8 0.7 7.5 3.7 3.7 3.6 1.6 10.6 0.9 1.1 0.5 1.4 7.2 7.3 0.7 9.7 8.4 2.7 2.0 2.0 37.6 0.0 0.0 0.0 8.9 0.0 5.3 1.0 1.7 3.8 0.0 0.3 2.8 3.2 0.0 0.3 0.0 0.0 1.4 1.8 6.7 9.5 21.0 6.4 7.0 6.6 9.5 3.2 6.9 7.9 0.0 5.4 0.9 2.8 3.5 17.4 5.1 10.2 1.4 2.3 0.0 39.3 2.0 5.0 2.5 80.9 3.7 1.3 0.0 3.5 1.6 6.9 5.8 1.1 1.0 0.7 19.1 20.8 3.1 0.8 165.3 176.9 0.8 11.8 0.0 11.2 71.0 2.6 3.5 417.9 1.1 13.5 38.8 4.2 3.3 33.2 3.9 1.1 4.3 5.0 1.1 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" NA NA Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.2 4.8 5.5 5.0 12.8 8.8 5.0 5.5 12.2 6.5 9.1 4.9 12.6 12.1 3.7 9.0 3.8 6.2 7.4 6.3 10.3 6.0 2.1 4.0 12.5 6.0 13.7 13.5 6.9 6.0 17.6 8.2 10.6 27.6 9.1 7.7 3.0 32.9 5.9 7.8 7.6 24.6 2.0 8.9 0.0 11.8 2.9 8.9 10.1 5.8 2.0 9.0 7.3 3.5 9.2 4.6 9.7 19.6 7.9 21.4 5.0 8.3 4.4 10.8 14.0 13.8 6.6 12.8 1.2 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 32.8 55.3 40.2 50.0 49.8 113.3 39.2 40.8 25.4 28.4 27.9 37.3 22.6 28.2 23.2 57.0 44.4 33.9 0.0 25.8 44.5 52.3 36.9 25.3 58.6 31.3 42.9 30.0 47.9 167.4 70.7 52.6 69.1 59.1 27.9 44.1 54.1 30.2 24.6 51.2 30.8 55.8 90.5 118.8 24.9 24.0 52.6 47.9 35.7 39.2 51.2 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase, receptor type B" P23467 12 70515866-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Endothelial cells: 113.4;Ito cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7 "memory B-cell: 3.5" "Lineage enriched" "Detected in single" 7 "B-cells: 3.5" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;hTERT-RPE1: 9.1;HUVEC TERT2: 28.0;TIME: 40.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 6700000 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 23.5 7.0 4.5 5.5 7.0 0.1 22.9 3.6 6.1 11.3 8.0 4.3 7.1 5.3 17.1 8.5 5.8 8.2 11.4 17.6 6.2 5.1 18.7 12.0 39.9 3.3 6.9 4.6 5.5 4.4 4.9 5.7 23.3 7.8 6.1 8.2 16.0 3.6 7.1 11.8 4.7 7.4 13.3 7.3 22.9 5.2 3.7 4.3 0.7 14.0 12.2 2.6 6.5 14.7 3.5 0.1 0.2 0.0 0.4 0.3 0.2 1.9 0.1 0.8 0.1 0.0 0.0 0.4 0.4 1.9 1.0 2.4 0.0 1.5 0.7 11.3 0.3 0.1 6.9 0.1 0.3 3.6 0.6 0.3 0.1 0.8 0.5 0.1 0.3 0.0 0.0 0.3 2.8 0.0 9.1 28.0 0.0 1.5 0.5 0.6 0.0 0.0 0.0 1.0 1.9 0.4 0.0 0.7 0.4 5.2 0.8 0.0 0.4 0.7 0.0 1.6 0.2 0.0 0.6 40.9 0.4 0.4 0.1 2.4 0.5 0.4 0.3 0.2 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 4.5 7.0 3.6 6.1 6.2 5.1 6.9 4.6 7.8 4.3 0.0 19.9 13.7 0.8 3.3 5.4 9.2 17.8 0.0 1.2 3.5 0.0 0.0 0.0 1.4 4.3 113.4 4.3 46.7 0.8 0.0 1.9 0.6 23.3 2.0 0.3 4.8 0.0 448.7 26.3 2.5 1.1 2.0 5.0 0.0 4.8 0.3 7.2 14.4 0.0 0.0 0.8 0.0 0.9 0.7 0.5 1.4 0.0 1.7 5.2 0.6 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase, receptor type C" 1 198638457-198757476 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 116.9;lymphoid tissue: 172.5" "Cell type enhanced" "Detected in many" 12 "B-cells: 266.4;granulocytes: 232.9;Kupffer cells: 338.8;Macrophages: 290.3;T-cells: 539.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 47.1;HEL: 26.6;HL-60: 24.0;JURKAT: 61.5;MOLT-4: 35.5;THP-1: 19.7;U-266/70: 22.0;U-266/84: 20.0;U-698: 28.2;U-937: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 9.8 2.9 3.4 48.0 6.2 36.1 4.3 1.3 3.5 3.1 5.6 2.8 0.5 4.9 2.9 3.9 4.8 5.6 8.8 4.9 3.9 4.5 4.4 5.2 27.5 93.2 7.9 1.3 2.9 2.1 0.3 2.5 4.5 5.3 4.2 5.8 3.3 10.7 1.0 1.7 2.5 22.2 4.5 13.2 89.3 6.5 2.3 5.3 172.5 4.6 3.9 53.2 13.1 3.7 28.5 42.8 94.7 103.8 53.7 76.1 116.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 47.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 26.6 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 61.5 0.5 0.7 0.0 0.0 35.5 14.5 0.1 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.1 0.0 0.0 19.7 0.3 0.0 0.2 0.1 0.1 22.0 20.0 28.2 0.0 21.5 0.1 20.8 52.0 56.3 76.1 99.7 64.5 28.5 52.9 72.7 42.8 26.8 60.2 60.3 94.7 53.7 103.8 6.4 54.6 116.9 3.4 6.2 1.3 3.5 3.9 4.5 7.9 1.3 5.3 5.3 41.7 86.9 266.4 0.7 14.1 0.0 4.1 7.6 21.4 26.1 1.8 0.0 0.4 0.0 0.0 2.0 11.9 0.1 23.3 0.0 0.5 8.9 0.9 232.9 3.0 90.3 0.0 1.2 14.1 338.8 1.5 1.1 290.3 20.3 120.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 6.5 4.3 0.2 0.2 13.2 0.7 539.1 0.5 0.9 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303726-48599436 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 19.6 21.5 14.9 23.2 18.4 14.7 28.1 25.6 19.4 18.0 13.2 11.5 19.0 12.3 16.8 19.5 27.9 12.7 15.3 19.5 15.4 15.3 18.1 12.1 25.4 30.1 17.0 11.8 15.2 11.6 12.8 17.2 21.5 16.0 15.5 15.3 11.6 20.0 17.4 27.9 20.3 14.3 16.8 23.6 29.4 13.7 14.4 15.3 39.1 19.9 15.8 25.3 17.4 23.6 20.5 10.3 13.2 12.2 3.6 4.6 4.0 9.1 4.9 13.5 14.5 6.7 7.8 6.1 18.0 15.0 19.0 16.2 4.2 16.2 11.8 4.2 12.0 10.5 12.7 17.5 14.5 29.0 16.5 6.7 21.7 10.2 7.2 7.1 18.6 20.6 4.3 8.9 12.3 15.8 15.9 13.1 29.2 7.2 9.7 21.7 4.3 58.2 9.4 6.6 20.8 5.4 25.0 13.5 13.5 19.7 8.9 0.6 13.8 17.8 8.9 14.7 12.5 9.7 24.3 10.1 11.8 7.7 14.3 16.2 4.3 1.2 0.1 6.2 11.7 15.9 11.0 9.7 5.0 4.6 12.2 3.7 17.4 3.8 4.6 9.3 20.5 3.2 3.8 13.2 3.6 12.1 10.3 4.5 4.0 14.9 18.4 25.6 19.4 15.4 15.3 17.0 11.8 16.0 15.3 3.0 18.7 56.5 18.3 25.2 14.4 15.9 17.8 20.1 14.8 29.6 27.5 5.9 13.3 15.8 20.6 33.6 15.9 0.0 10.4 8.0 15.4 21.4 11.5 14.7 64.6 17.5 16.8 38.6 83.9 10.6 24.2 88.8 25.3 107.4 18.5 21.8 13.3 9.9 26.9 21.1 18.5 19.4 20.6 27.9 14.3 33.4 3.7 20.8 15.0 14.4 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" 8 144511288-144517845 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.0;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in many" 13 "Extravillous trophoblasts: 7.1;Spermatocytes: 12.6;Spermatogonia: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 14 "B-cells: 1.9;monocytes: 1.0;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 2.0 1.6 2.6 12.3 5.6 21.0 2.8 11.5 3.7 1.8 4.3 1.5 1.6 5.6 2.5 4.9 9.4 1.5 1.9 1.9 2.3 1.7 1.6 1.9 1.6 5.9 1.5 2.2 1.9 3.5 0.3 2.4 2.7 2.2 7.7 1.5 1.4 5.4 0.9 2.1 9.4 4.8 1.1 1.7 4.7 3.0 18.1 1.8 18.9 2.5 5.3 8.0 1.6 1.8 1.9 0.1 0.0 1.0 0.0 1.6 0.2 10.4 18.7 8.7 18.4 0.5 0.9 15.3 10.6 1.9 7.9 6.6 18.4 15.5 7.1 7.1 1.7 4.6 12.7 5.8 4.5 2.2 12.5 22.0 25.7 32.0 13.7 0.1 6.5 21.5 1.1 0.6 8.8 1.8 1.1 2.2 14.6 25.5 9.3 2.7 32.4 23.7 17.7 6.1 8.7 22.4 24.9 6.9 11.9 2.1 11.3 17.3 10.4 14.4 12.1 3.7 2.5 14.7 14.4 2.9 12.8 38.7 15.3 19.5 5.2 5.4 12.1 7.3 20.2 12.8 0.0 0.1 0.0 1.1 1.0 0.0 1.9 0.5 1.1 0.1 0.0 0.9 1.6 0.0 0.0 0.0 0.1 0.0 0.2 2.6 5.6 11.5 3.7 2.3 1.7 1.5 2.2 2.2 1.8 0.0 0.0 2.2 0.4 1.3 2.5 1.6 2.5 0.0 0.0 0.0 3.9 1.2 0.0 0.4 3.1 0.0 0.4 0.0 0.4 7.1 0.8 0.5 0.0 0.6 3.0 0.0 0.0 0.0 0.3 6.2 1.1 0.6 0.0 0.0 1.4 0.2 0.3 0.0 1.4 0.3 1.6 0.0 0.4 12.6 21.1 0.9 1.3 0.0 3.1 0.4 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58352500-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 33.4;Mucus-secreting cells: 39.0;Undifferentiated cells: 47.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.7" "Region enriched" "Detected in many" 7 "cerebellum: 30.6" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 13.4;Hep G2: 26.2;OE19: 29.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008079 Uncertain NA NA "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.4 9.4 2.2 6.2 3.5 1.9 4.5 30.6 4.3 3.4 26.4 0.9 21.3 18.5 1.7 9.1 10.0 3.9 8.1 3.3 1.9 1.3 8.0 7.0 6.1 2.7 0.8 1.1 1.6 13.2 3.0 13.3 8.7 4.1 8.0 16.3 3.8 13.7 19.0 0.5 8.9 29.0 0.9 0.8 0.9 4.9 3.1 0.7 3.0 1.8 5.7 6.6 4.0 4.4 0.9 1.1 1.7 1.8 5.6 3.6 1.2 0.6 9.3 1.7 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 13.4 4.5 3.8 4.8 0.0 1.1 2.6 0.3 3.6 0.0 7.9 6.5 3.0 0.4 26.2 0.0 3.7 2.7 0.0 7.4 0.0 1.1 0.5 0.0 1.2 0.2 3.3 0.0 0.1 2.0 3.5 0.2 29.2 0.6 6.2 0.0 2.0 3.3 5.1 1.0 0.3 0.8 0.4 0.3 3.2 1.1 1.0 0.0 0.1 1.1 0.0 0.0 3.4 1.6 2.9 0.3 0.4 2.2 1.7 0.2 1.6 3.1 0.8 3.2 0.9 2.5 3.6 0.4 0.9 2.3 3.0 0.8 5.6 1.8 1.1 1.2 1.2 2.2 3.5 30.6 4.3 1.9 1.3 0.8 1.1 4.1 0.7 3.0 6.2 0.5 15.7 8.5 2.4 3.5 10.2 4.0 3.4 17.4 2.0 19.4 13.3 5.6 1.2 0.7 33.4 0.0 2.4 2.2 0.6 8.7 0.0 8.7 2.3 4.8 14.9 0.6 0.6 1.3 0.3 0.7 13.5 2.8 39.0 11.7 4.5 24.6 0.4 2.2 2.8 0.0 0.4 1.1 0.5 5.4 4.9 3.9 47.8 5.4 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086773-112120013 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Distal tubular cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 20.9 23.1 17.1 21.7 19.4 10.9 19.6 14.1 18.4 18.1 33.6 14.2 23.9 36.0 22.7 17.5 35.2 17.3 17.9 42.5 15.1 13.7 66.6 75.4 19.1 23.3 17.1 15.1 18.6 23.2 22.5 16.1 20.1 18.0 23.7 33.9 15.7 32.6 21.7 65.4 15.5 61.2 24.0 15.3 22.8 22.2 8.8 14.8 21.7 46.2 33.9 24.6 23.5 20.3 55.5 74.7 62.1 91.7 46.1 53.7 68.9 16.7 17.2 11.7 17.7 43.8 35.2 19.7 20.4 29.0 21.4 26.9 59.4 43.9 30.4 63.1 27.5 31.7 42.0 36.5 28.9 26.3 27.0 18.3 28.9 12.8 31.5 34.1 45.5 22.0 38.8 32.0 25.5 40.8 25.6 30.1 22.0 29.8 42.0 26.5 21.0 27.3 41.2 15.8 64.5 42.6 25.3 31.1 56.7 43.8 40.9 16.9 11.2 28.6 38.7 20.3 17.7 39.8 32.8 23.5 20.9 27.4 23.2 18.7 12.5 16.0 55.7 11.9 59.6 19.9 46.1 73.0 48.7 41.4 91.7 44.1 55.5 44.5 43.1 74.7 45.6 53.7 49.8 62.1 46.1 70.7 36.8 44.2 68.9 17.1 19.4 14.1 18.4 15.1 13.7 17.1 15.1 18.0 14.8 74.5 39.0 90.1 83.6 72.5 10.9 198.1 91.7 68.3 63.7 85.5 7.9 134.7 449.3 67.9 8.3 67.1 194.1 46.7 51.2 94.9 111.1 52.7 63.6 160.7 147.1 11.1 48.5 66.9 103.7 21.8 96.4 98.5 72.6 129.8 105.1 39.2 45.9 122.4 93.7 350.8 18.5 90.5 100.9 53.9 50.7 65.1 149.7 72.6 141.2 82.2 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2" Q9BYW2 3 47016429-47163967 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favorable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 13.2 10.5 12.2 15.2 15.4 20.0 11.7 22.4 16.4 13.4 14.0 9.1 12.9 9.5 15.8 7.5 10.8 11.4 8.7 8.8 10.6 6.8 11.4 10.3 10.4 11.8 11.7 9.5 16.0 13.4 21.4 16.3 10.7 11.3 12.4 10.9 7.7 12.7 14.8 27.6 12.5 11.5 11.9 9.8 13.8 10.4 12.8 12.8 23.2 15.8 5.5 12.8 16.1 15.5 4.8 2.6 6.0 2.3 7.1 3.9 1.0 11.6 9.2 15.4 7.9 9.3 10.7 6.5 10.7 10.4 12.6 11.5 9.7 7.6 25.7 6.7 14.8 12.3 7.1 16.7 10.2 17.1 14.7 6.6 26.4 15.3 7.5 7.0 19.7 15.3 9.2 9.9 12.4 15.4 10.2 11.6 13.3 16.9 9.7 10.3 6.1 14.5 2.6 11.7 5.6 7.7 9.6 15.0 13.3 6.4 15.3 6.7 10.6 18.1 7.1 6.7 11.5 7.5 14.7 14.8 13.9 10.4 11.8 17.1 12.5 13.9 26.0 8.0 11.3 8.1 2.4 2.2 5.2 3.9 2.3 2.4 3.7 2.4 3.0 2.5 4.8 3.5 3.0 6.0 7.1 1.9 2.6 1.0 1.0 12.2 15.4 22.4 16.4 10.6 6.8 11.7 9.5 11.3 12.8 44.7 53.3 20.6 20.5 29.7 33.4 58.5 22.9 66.9 80.8 10.4 39.3 16.3 10.0 17.4 24.0 29.3 26.5 0.0 19.3 10.1 20.8 25.9 55.6 26.7 14.3 25.4 21.2 23.4 27.2 20.8 28.1 21.6 16.9 20.8 27.8 21.7 20.0 17.5 31.1 9.3 37.0 12.9 21.7 78.1 18.9 31.1 15.4 27.7 24.8 34.2 SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960825-11079426 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Cardiomyocytes: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004208 Supported Supported Nucleoplasm NA NA 260000 Nucleoplasm "CAB004208: AB_626762" "unprognostic (2.68e-1)" "unprognostic (4.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.43e-3)" "unprognostic (1.40e-1)" "unprognostic (6.33e-3)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-2)" "unprognostic (6.80e-3)" "unprognostic (6.83e-3)" "unprognostic (5.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 10.3 12.4 15.5 18.0 21.3 20.5 10.9 29.1 28.0 13.2 12.8 16.6 9.7 14.3 16.6 9.4 24.7 15.7 12.8 11.6 14.4 17.7 13.0 9.9 13.0 18.1 17.1 16.8 13.6 13.4 18.1 11.5 14.6 16.1 13.3 9.4 17.3 18.2 12.5 21.9 20.4 12.0 10.6 16.1 13.2 14.5 22.2 12.4 58.2 15.5 10.1 21.5 15.2 12.6 9.8 11.2 8.6 13.5 11.4 13.7 5.9 20.5 1.1 36.7 34.7 7.2 6.1 16.1 14.3 8.6 17.5 13.0 28.7 0.9 48.3 22.2 12.5 0.7 15.1 28.6 17.7 9.7 19.8 21.4 38.4 18.2 33.3 10.9 27.8 19.2 10.2 8.6 14.7 15.2 7.8 15.6 21.1 34.4 18.2 13.7 41.9 46.2 23.9 37.2 10.0 31.1 49.2 23.2 25.0 11.2 26.1 41.8 37.9 15.2 19.6 16.3 12.3 16.6 20.9 20.6 26.1 13.6 23.8 23.6 37.7 41.8 47.9 14.8 26.7 22.1 8.1 8.3 8.6 13.7 9.5 12.2 7.4 10.4 11.6 8.5 9.8 11.4 11.2 5.2 11.4 13.5 11.2 8.8 5.9 15.5 21.3 29.1 28.0 14.4 17.7 17.1 16.8 16.1 12.4 62.5 67.7 32.7 32.8 32.7 82.3 219.1 43.3 46.8 51.2 41.8 66.8 57.1 34.9 75.0 39.4 30.8 34.6 23.3 53.1 46.8 38.0 38.3 29.0 19.2 36.4 95.3 60.6 22.7 21.0 29.3 24.2 23.3 15.1 57.7 37.3 37.2 60.6 38.6 12.7 19.3 63.8 12.9 30.3 93.0 96.0 45.2 51.0 28.4 50.9 40.7 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838008 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease mutation, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 11.0 15.2 14.6 33.2 15.4 16.9 12.1 30.4 21.9 13.4 25.1 16.4 11.4 41.1 17.2 11.0 15.6 12.3 15.0 12.6 13.2 14.2 14.6 11.7 14.0 32.8 13.0 13.8 21.3 16.1 7.9 15.7 20.8 12.8 11.0 9.4 16.7 40.9 13.1 28.1 14.7 27.4 10.6 12.8 19.8 24.1 37.7 12.9 29.4 15.7 12.0 16.0 21.1 12.2 19.5 9.9 4.8 11.6 7.0 7.5 5.9 1.5 1.0 19.2 1.8 1.8 0.5 3.9 6.1 1.8 1.8 2.9 2.2 1.8 15.7 5.3 0.8 2.0 2.9 4.6 3.0 3.0 2.6 6.7 13.0 1.8 1.3 2.1 13.8 3.8 1.1 2.2 2.1 4.7 0.9 0.9 1.9 3.5 8.7 1.1 3.9 11.2 3.2 5.7 4.7 3.8 7.0 15.5 7.0 1.6 3.0 9.1 6.9 1.4 0.4 10.3 10.4 1.5 2.1 1.6 1.6 6.7 2.6 1.7 9.6 8.8 10.4 1.3 7.6 4.6 4.0 10.0 4.8 3.8 10.2 5.2 19.5 4.6 4.6 9.3 6.4 3.8 2.5 0.8 7.0 11.6 9.9 7.5 5.9 14.6 15.4 30.4 21.9 13.2 14.2 13.0 13.8 12.8 12.9 6.0 10.4 102.1 57.3 44.6 51.7 3.7 38.2 18.7 6.8 45.4 19.6 106.2 71.3 80.0 26.9 31.5 31.9 23.3 67.3 185.0 45.7 53.3 33.5 17.7 66.6 63.5 68.9 36.8 19.7 12.4 33.1 35.4 54.0 63.1 50.5 72.3 62.0 51.8 30.1 65.4 36.9 19.4 58.2 125.7 116.1 46.3 133.9 35.0 61.6 56.7 STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported NA NA "HPA002857: AB_1079861" "unprognostic (1.62e-1)" "unprognostic (1.01e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.70e-2)" "unprognostic (3.77e-2)" "unprognostic (9.67e-3)" "unprognostic (4.68e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.81e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.97e-1)" 24.0 18.8 21.5 23.9 23.7 39.7 30.1 35.4 23.5 28.1 25.1 16.4 25.2 14.9 24.3 21.0 24.3 20.0 16.3 15.7 21.4 17.9 22.2 18.1 23.4 26.2 24.9 17.5 31.1 19.7 46.1 27.6 25.5 20.6 25.9 18.3 14.2 20.7 27.8 27.6 18.9 21.9 25.9 30.6 26.7 17.6 9.3 26.4 69.3 32.0 19.7 27.1 37.7 37.8 12.8 12.5 30.3 14.4 12.1 15.5 6.7 17.5 16.5 24.9 15.7 10.7 16.2 16.1 16.6 17.9 17.3 21.8 15.4 18.8 32.4 23.6 14.9 19.4 16.0 50.9 14.1 24.5 23.0 21.7 29.9 33.1 10.1 11.1 39.1 23.6 12.7 14.0 20.5 33.1 15.0 14.5 33.1 29.2 34.6 12.7 19.1 50.0 17.6 13.0 16.1 24.6 35.5 32.9 27.1 13.4 33.5 22.5 17.9 37.5 14.0 19.7 18.6 8.4 18.0 17.6 0.1 9.3 20.3 18.9 14.9 22.5 40.7 10.9 24.1 17.4 16.8 10.2 18.1 10.8 13.1 12.6 10.0 11.2 10.1 12.5 12.8 15.5 12.4 30.3 12.1 14.4 11.2 8.7 6.7 21.5 23.7 35.4 23.5 21.4 17.9 24.9 17.5 20.6 26.4 59.6 44.6 53.3 44.3 49.9 49.3 38.4 28.1 60.2 64.8 41.8 56.9 28.0 18.3 37.3 0.9 53.4 25.6 46.7 33.1 27.7 48.0 69.8 54.5 35.8 31.4 42.9 55.8 46.6 58.6 1.6 60.9 61.9 32.1 38.7 36.8 54.0 42.5 20.1 65.0 27.0 60.0 64.7 43.2 7.0 11.3 49.1 59.7 50.7 37.9 72.3 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 124.0;Late spermatids: 234.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.2 10.3 7.8 14.8 7.4 6.7 16.5 10.4 10.9 9.8 10.4 8.4 14.9 13.9 11.5 10.8 4.4 13.8 7.7 16.0 3.0 26.0 18.8 14.2 0.6 10.5 16.0 14.3 23.9 12.2 11.7 7.5 11.2 8.9 9.8 11.1 26.6 19.2 5.5 15.9 13.7 14.5 15.0 7.3 12.7 21.8 8.4 15.6 8.8 15.6 18.1 13.1 0.0 7.7 11.2 4.7 12.1 23.5 13.2 10.1 11.5 19.8 16.5 37.8 15.9 10.4 10.1 19.1 10.4 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 6.0 13.6 11.1 6.4 14.8 23.6 11.8 17.8 2.7 6.8 22.7 17.7 6.7 6.6 8.1 124.0 14.7 29.5 0.0 11.9 4.5 10.4 14.2 2.3 25.2 12.9 17.5 14.5 16.0 22.2 234.7 22.7 10.4 15.1 17.2 29.2 19.3 13.0 25.9 19.4 8.6 19.8 12.9 20.8 49.9 19.4 13.6 7.3 8.6 33.0 10.9 SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503987-102633535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease mutation, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 126.0;Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA008700: AB_1080125" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.15e-3)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-2)" "unprognostic (3.82e-3)" 10.7 12.8 15.0 15.2 12.8 3.9 18.3 23.0 15.3 13.4 10.4 11.3 12.1 7.7 14.4 13.3 14.7 14.2 16.2 11.0 11.8 7.8 10.8 10.0 21.4 20.5 11.9 11.0 18.0 8.9 20.0 7.8 13.9 10.0 15.4 8.8 11.9 12.6 16.7 14.1 23.1 9.4 14.3 10.7 13.1 7.9 21.1 13.1 19.9 6.2 12.7 15.0 15.2 15.0 2.3 4.5 6.2 5.5 2.8 3.1 2.8 6.3 6.7 10.9 15.7 11.3 9.5 5.3 6.6 12.8 9.6 8.7 6.2 4.7 6.5 18.8 7.3 3.9 4.5 13.4 7.3 6.3 4.0 10.4 15.5 3.9 5.9 5.4 5.6 11.2 10.9 5.8 7.1 5.8 17.6 12.3 6.4 3.4 6.0 5.8 5.3 10.6 8.5 3.1 4.1 5.1 11.5 11.8 3.4 6.3 9.5 3.7 5.9 5.2 4.9 5.9 10.5 10.8 3.7 13.5 4.3 6.1 4.5 7.2 4.9 3.2 4.7 5.3 11.0 2.9 4.2 4.5 6.2 2.5 5.5 2.0 2.3 3.1 2.8 4.5 2.1 2.2 2.5 1.1 2.8 5.5 2.5 1.9 2.8 15.0 12.8 23.0 15.3 11.8 7.8 11.9 11.0 10.0 13.1 0.0 3.0 0.9 2.2 2.7 3.4 3.6 0.0 4.0 4.5 3.5 7.9 6.9 1.7 3.9 126.0 4.3 4.0 0.0 2.6 3.1 5.4 1.9 3.5 4.9 10.4 1.6 1.2 12.9 10.2 78.9 4.6 5.6 0.0 7.2 2.2 2.9 3.5 0.0 6.3 4.4 3.9 0.0 3.4 4.2 4.5 5.6 5.8 5.1 2.8 1.1 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 10.4 13.6 15.8 8.8 26.8 13.6 11.4 32.1 28.3 12.7 10.8 22.6 7.9 9.1 14.6 12.3 10.9 12.4 9.7 17.6 13.0 12.1 13.1 9.4 11.6 10.2 12.5 15.1 21.2 12.1 15.9 19.5 15.8 21.1 11.8 12.6 13.1 11.6 10.4 20.0 13.8 11.2 14.2 12.4 13.7 10.6 36.2 14.9 10.5 16.2 8.6 14.2 10.9 11.1 2.8 3.1 4.8 7.0 4.9 7.1 2.6 6.2 7.4 10.1 8.3 10.4 9.9 19.0 8.4 13.6 8.8 8.7 12.5 7.3 14.6 3.7 16.0 13.4 16.2 11.9 8.5 9.0 7.0 6.3 4.6 14.7 10.2 12.4 6.8 6.3 10.7 6.4 11.2 13.8 8.8 10.1 13.0 8.1 8.0 10.0 11.5 6.1 5.8 13.9 9.2 6.2 7.4 19.1 8.2 3.9 8.2 5.1 7.8 9.8 6.1 4.8 12.5 11.1 4.0 10.4 14.4 8.7 8.6 5.7 4.5 10.0 14.2 8.2 4.0 6.4 4.1 4.4 4.8 6.5 7.0 7.1 1.9 3.6 5.7 3.1 2.8 5.9 5.3 1.7 4.9 3.2 1.8 5.7 2.6 15.8 26.8 32.1 28.3 13.0 12.1 12.5 15.1 21.1 14.9 20.8 25.6 10.8 4.8 6.6 26.0 26.6 7.6 21.4 12.5 10.4 35.3 12.8 11.6 9.5 39.6 8.7 6.3 0.0 6.2 19.5 9.1 6.5 8.1 5.0 7.8 23.8 16.1 12.3 8.7 99.6 14.4 7.4 11.8 8.2 7.9 10.4 10.9 8.4 10.6 7.5 25.2 19.4 8.0 18.9 17.8 7.5 17.6 7.1 9.9 6.5 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047465-2089487 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 13.9 11.9 16.9 12.4 20.0 10.9 13.2 35.1 26.9 20.5 17.0 19.4 17.9 14.0 20.1 12.2 13.0 18.6 15.0 14.0 13.3 8.8 11.8 9.8 12.7 10.1 13.8 14.7 21.1 16.1 20.0 18.1 10.6 14.6 13.8 10.8 16.7 22.9 19.6 31.7 14.5 13.2 13.5 11.4 12.9 16.6 21.4 12.9 14.1 20.1 11.3 10.9 18.0 14.0 4.7 5.6 7.7 4.9 3.6 7.0 3.7 7.2 11.6 16.1 18.2 19.2 16.2 13.6 17.4 11.9 13.1 11.2 13.9 13.8 10.9 15.5 14.3 6.1 12.0 9.6 12.6 9.8 8.3 15.8 10.3 22.5 5.7 13.2 12.8 12.5 19.1 8.0 10.6 7.9 15.8 12.3 7.9 10.0 9.8 11.6 14.4 15.2 3.7 16.7 5.4 11.4 24.2 17.6 13.9 5.3 6.5 12.2 23.1 24.8 16.4 8.8 16.7 15.0 9.5 19.4 13.8 9.4 12.3 8.8 21.9 21.8 21.8 5.7 5.2 16.3 6.2 4.9 5.4 7.0 4.7 6.7 4.4 4.4 4.1 5.6 4.7 3.1 4.8 7.7 3.6 3.7 1.5 3.2 3.7 16.9 20.0 35.1 26.9 13.3 8.8 13.8 14.7 14.6 12.9 23.8 17.6 14.9 7.2 8.1 44.2 38.9 20.4 9.4 10.3 19.2 88.4 10.1 3.3 12.8 11.0 19.5 25.8 0.0 12.2 6.5 14.6 9.4 8.1 29.2 9.8 42.9 31.2 34.4 10.5 22.4 26.2 16.6 8.5 7.2 23.8 24.1 15.9 17.5 24.4 6.7 69.1 12.9 11.8 19.4 39.6 8.5 7.8 20.0 24.7 9.2 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102253012-102412841 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA053688: AB_2682230" "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 27.0 16.7 27.1 29.5 31.7 30.3 29.2 40.8 32.8 24.9 25.0 19.1 21.1 14.4 26.8 24.0 23.8 22.0 17.6 22.7 25.5 15.3 17.9 17.0 24.2 29.6 21.9 20.6 29.7 22.2 32.4 25.5 25.0 23.6 20.2 17.1 19.7 22.9 21.8 39.9 29.7 22.4 29.3 17.5 21.9 21.1 39.7 28.3 37.9 20.3 15.9 27.0 27.5 28.6 5.0 4.0 6.3 5.5 2.4 7.1 2.1 23.6 10.6 20.5 10.4 20.2 20.6 18.9 17.9 15.8 14.0 12.3 10.6 15.9 47.1 15.5 16.7 9.2 14.4 17.5 15.5 19.7 20.4 8.6 39.3 14.5 19.0 18.0 12.2 21.7 23.6 15.5 14.4 25.2 16.0 16.8 13.5 18.9 26.8 13.7 21.4 31.0 14.6 15.4 22.9 12.0 18.1 12.1 22.3 12.8 23.2 15.1 12.6 12.5 12.1 12.4 18.6 19.6 13.0 16.8 15.0 17.5 13.4 12.4 14.4 13.8 48.5 14.8 19.1 12.1 3.1 3.4 5.0 5.6 3.4 5.6 5.0 6.0 5.9 4.0 3.9 4.8 7.1 6.3 2.4 5.5 3.6 7.1 2.1 27.1 31.7 40.8 32.8 25.5 15.3 21.9 20.6 23.6 28.3 23.8 27.7 29.8 38.5 46.4 48.4 35.8 5.1 40.2 63.7 29.6 64.8 19.1 8.3 15.1 25.0 38.3 17.3 0.0 13.1 14.9 48.2 37.7 28.9 15.8 15.4 54.0 32.0 23.4 29.4 20.2 36.8 28.9 42.2 27.1 17.9 31.5 16.2 17.3 34.3 6.7 44.0 12.9 38.7 64.7 30.4 53.3 58.2 30.5 17.7 46.9 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141008-10152220 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 54.7" "CAB005430, HPA031631, HPA031632" Uncertain Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB005430: AB_2241850, HPA031631: AB_2673968, HPA031632: AB_2673969" "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 13.8 17.4 18.1 29.2 18.4 24.3 15.4 25.8 21.4 13.3 19.8 19.3 14.5 15.9 15.1 13.6 16.4 14.3 18.9 10.5 17.1 18.5 13.7 16.3 14.6 27.9 13.5 12.3 15.2 22.5 13.8 14.6 18.8 12.8 15.1 16.6 12.5 21.8 13.7 14.8 14.0 22.3 13.4 17.0 22.6 16.2 17.9 11.2 39.2 16.9 11.5 29.3 15.4 19.1 5.4 3.9 8.0 4.1 4.4 4.3 1.7 6.8 6.6 14.6 8.9 13.6 10.5 54.7 6.1 8.7 7.8 9.2 7.8 8.6 24.3 8.3 8.2 11.0 5.9 13.5 8.5 9.6 11.6 12.2 18.9 10.8 10.7 12.9 16.6 15.2 10.6 9.7 10.3 13.0 10.4 8.9 15.3 16.8 18.5 7.6 12.4 15.8 12.2 9.8 7.4 8.5 20.1 12.9 12.2 9.5 17.8 5.5 18.3 12.8 6.8 7.3 9.2 13.4 21.1 7.7 7.7 10.4 7.2 9.5 13.2 26.9 38.8 8.6 20.0 7.0 2.6 4.1 3.3 3.8 2.5 3.6 4.1 2.9 4.3 3.9 5.4 2.5 2.7 8.0 4.4 3.2 2.4 3.1 1.7 18.1 18.4 25.8 21.4 17.1 18.5 13.5 12.3 12.8 11.2 11.9 12.2 25.5 15.5 13.1 15.6 5.0 20.4 5.3 5.7 15.7 17.7 13.9 6.6 9.9 7.6 12.1 10.5 0.0 4.5 15.8 9.5 19.0 4.7 12.3 12.9 17.5 13.8 17.2 20.2 6.1 13.0 18.5 11.8 15.4 9.3 10.4 8.5 9.3 10.6 7.3 13.9 6.5 6.2 14.4 25.6 17.9 14.4 17.5 10.7 19.5 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "Wiskott-Aldrich syndrome" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.7;lymphoid tissue: 55.9" "Cell type enhanced" "Detected in many" 8 "B-cells: 72.2;Hofbauer cells: 95.2;Kupffer cells: 94.9;Macrophages: 70.0;T-cells: 87.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 20.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 21.7;HEL: 19.1;HMC-1: 46.5;MOLT-4: 19.7;NB-4: 21.5;RPMI-8226: 26.5;THP-1: 19.5;U-266/70: 24.6;U-937: 24.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 320000 "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 7.6 4.0 4.9 28.9 7.8 30.7 3.3 2.0 5.1 2.7 4.4 5.9 0.5 4.8 2.4 5.6 3.7 4.5 4.4 3.0 4.6 4.1 4.1 5.0 12.6 29.9 7.6 1.3 2.6 2.2 0.7 2.6 5.4 6.0 3.2 3.2 3.5 5.4 1.9 1.4 2.2 14.3 3.7 12.8 55.9 4.1 1.7 7.3 53.2 2.8 1.4 33.2 5.8 2.5 2.1 3.5 20.3 5.3 2.1 3.2 2.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 21.7 0.1 0.0 0.1 0.7 0.0 0.0 0.0 12.5 0.1 19.1 0.2 0.0 0.2 9.8 46.5 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.2 13.4 0.0 2.2 19.7 21.5 0.1 0.3 0.1 17.3 0.0 26.5 0.0 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.1 19.5 0.1 0.0 0.1 0.3 0.0 24.6 12.0 15.2 0.1 24.8 0.0 1.8 4.6 20.3 3.0 5.0 2.2 1.8 2.3 2.5 3.5 2.1 2.1 2.3 18.1 2.1 5.3 1.8 3.2 2.0 4.9 7.8 2.0 5.1 4.6 4.1 7.6 1.3 6.0 7.3 3.0 21.3 72.2 0.1 2.2 0.0 0.8 0.0 2.7 0.0 0.0 0.0 0.8 1.7 0.1 0.5 0.5 0.0 23.3 0.3 0.9 1.5 0.2 46.2 0.9 95.2 0.0 1.2 5.5 94.9 0.8 0.0 70.0 3.3 45.9 0.0 0.2 0.1 0.0 0.0 1.5 0.0 0.0 0.6 1.4 1.1 1.3 1.1 87.0 0.0 0.1 WRN "RECQ3, RECQL2" ENSG00000165392 "Werner syndrome RecQ like helicase" Q14191 8 31033801-31173769 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 10.1 9.2 5.6 8.5 6.6 15.6 11.1 10.7 7.3 14.2 8.0 7.7 7.7 5.5 24.4 8.8 7.6 9.7 6.9 7.0 5.9 4.0 5.1 7.7 7.2 6.7 8.2 5.3 12.0 9.9 7.8 28.1 8.5 7.0 8.6 7.8 8.3 10.8 7.8 7.7 10.2 7.0 12.1 14.9 8.9 8.3 10.4 7.3 11.8 7.9 6.3 9.3 10.8 8.7 3.9 2.7 1.3 1.9 2.9 6.2 1.6 6.5 6.4 13.3 8.4 8.0 12.8 8.4 7.4 7.3 9.1 9.5 4.1 4.0 15.4 6.8 7.5 6.9 3.4 8.2 5.3 13.6 4.3 7.0 15.7 6.1 3.4 10.0 9.3 5.8 9.3 5.9 8.6 10.4 4.5 8.7 10.8 24.8 9.7 8.3 4.2 19.3 4.5 11.4 7.1 4.6 11.1 10.1 6.2 3.8 7.2 2.9 7.7 9.0 5.1 7.0 7.8 3.5 4.6 13.9 9.9 6.1 5.0 6.2 2.6 2.8 19.3 7.3 7.3 6.8 1.2 1.9 1.3 3.3 1.9 6.2 3.9 3.8 3.3 2.7 3.5 2.5 3.2 0.5 2.9 0.8 2.0 2.8 1.6 5.6 6.6 10.7 7.3 5.9 4.0 8.2 5.3 7.0 7.3 8.9 8.8 10.8 8.0 11.9 14.2 6.5 12.7 9.4 11.4 15.7 21.6 5.9 1.7 5.1 37.8 8.5 3.2 23.3 8.4 4.7 10.8 8.1 2.3 8.9 4.5 14.3 2.4 6.2 5.1 8.1 17.5 4.9 10.1 5.4 12.1 21.9 7.1 2.9 13.4 2.1 22.1 6.5 9.5 8.7 18.6 8.9 4.7 5.1 7.6 9.8 WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "Wilms tumor 1" P19544 11 32387775-32435630 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 69.0;fallopian tube: 34.5;ovary: 53.4" "Cell type enhanced" "Detected in some" 18 "Collecting duct cells: 19.2;Late spermatids: 5.9;Leydig cells: 7.8;Sertoli cells: 6.5" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.5;HMC-1: 17.4;K-562: 12.2;NB-4: 32.6;THP-1: 15.6" "Region enhanced" "Detected in single" "pons and medulla: 0.5" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" 10.3 0.0 0.2 1.8 0.6 0.0 0.2 0.2 0.5 20.3 1.5 0.2 3.7 0.0 69.0 9.3 0.4 34.5 0.8 2.1 0.9 0.0 5.3 0.2 0.8 0.5 0.2 0.2 53.4 0.2 0.0 0.2 6.9 0.3 0.9 0.0 0.2 0.2 4.2 0.2 0.0 0.4 23.7 0.2 14.6 0.0 24.5 0.2 0.2 0.3 0.2 0.2 1.3 4.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 4.7 13.5 0.0 1.2 3.8 9.0 17.4 0.0 0.0 2.8 0.0 0.0 0.0 2.8 12.2 0.1 2.7 0.0 7.9 32.6 0.7 0.0 3.8 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 1.8 15.6 0.1 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 0.2 0.5 0.9 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 19.2 0.0 0.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 5.9 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 0.0 6.5 0.0 1.9 0.9 0.0 0.7 0.0 0.0 0.1 XPA "XP1, XPAC" ENSG00000136936 "XPA, DNA damage recognition and repair factor" P23025 9 97674909-97697357 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease mutation, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000155, HPA056856" Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes No Nucleoplasm "Cytokinetic bridge" "CAB000155: , HPA056856: AB_2683258" "unprognostic (8.76e-2)" "unprognostic (1.05e-3)" "unprognostic (1.60e-1)" "unprognostic (2.30e-2)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (5.26e-2)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.55e-3)" "prognostic favorable (4.28e-5)" "unprognostic (2.19e-2)" "unprognostic (1.56e-1)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" 18.7 17.5 20.1 17.1 21.0 10.6 17.4 26.8 20.8 20.3 25.2 17.2 11.7 20.6 25.5 15.4 18.9 15.0 19.5 12.9 17.2 15.3 24.9 24.2 14.8 16.7 18.6 17.5 17.2 14.5 23.0 23.1 12.8 17.7 20.3 13.6 16.4 16.1 21.7 43.3 16.3 22.2 27.5 17.1 16.2 25.1 6.4 15.8 15.7 31.5 11.9 21.6 22.0 16.4 22.2 23.4 12.7 15.8 19.7 21.6 11.3 23.0 5.4 8.1 10.0 9.9 9.7 5.6 6.3 10.0 11.5 7.8 14.1 19.4 13.0 6.1 6.9 7.7 11.6 6.4 7.6 9.8 8.9 12.9 10.2 11.8 7.8 10.8 12.1 12.4 8.4 8.2 5.3 5.5 7.8 12.8 10.8 14.1 10.2 6.3 7.2 15.7 14.6 5.5 22.0 9.0 16.0 17.3 11.0 18.3 9.0 11.4 11.5 9.0 6.9 8.1 6.4 10.1 7.3 8.0 4.0 10.1 15.9 13.6 18.1 14.5 8.2 10.0 8.7 7.9 6.0 13.3 12.7 16.2 13.1 18.7 19.5 17.7 15.6 13.5 22.2 21.6 18.6 1.5 19.7 15.8 23.4 18.3 11.3 20.1 21.0 26.8 20.8 17.2 15.3 18.6 17.5 17.7 15.8 23.8 31.5 27.5 17.4 15.3 99.5 29.1 50.9 34.8 40.9 21.0 76.6 27.4 102.8 31.2 1.2 29.2 16.9 0.0 33.5 8.3 24.2 16.3 29.0 40.6 30.4 79.4 21.5 17.8 17.5 2.6 40.9 29.8 13.5 49.5 21.3 71.6 24.5 21.0 44.6 38.3 99.8 32.3 31.9 12.8 16.4 16.4 11.7 25.3 26.3 20.2 XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178783 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease mutation, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167" "unprognostic (7.46e-2)" "unprognostic (2.52e-2)" "unprognostic (4.50e-2)" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (2.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.65e-2)" "unprognostic (1.50e-1)" "unprognostic (7.13e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "prognostic favorable (4.14e-7)" "unprognostic (1.59e-1)" "unprognostic (7.88e-2)" "unprognostic (7.62e-2)" "prognostic favorable (2.46e-4)" 20.2 17.1 14.2 24.0 30.2 8.4 21.4 16.1 19.3 22.3 18.9 20.8 27.5 18.0 24.6 18.3 16.9 24.9 25.1 12.4 16.2 14.4 24.6 23.4 19.9 21.1 33.4 15.2 35.0 20.9 35.4 26.7 28.0 22.1 20.9 15.9 16.7 17.6 30.3 22.4 30.5 23.6 17.7 22.6 23.3 15.9 12.9 30.6 18.5 25.7 12.4 20.8 22.4 22.3 10.9 7.0 34.6 8.8 8.8 12.2 6.1 4.5 11.6 13.1 8.4 19.7 13.6 44.5 11.3 32.3 10.9 8.5 4.2 5.4 15.1 5.0 13.7 5.1 5.7 8.6 18.0 9.0 6.1 7.4 8.0 12.3 7.8 17.5 6.0 15.3 19.3 21.4 14.5 29.1 12.8 12.9 6.9 11.0 8.2 12.1 9.5 4.9 5.7 7.8 7.4 7.9 6.3 5.9 12.1 13.8 13.5 2.8 10.2 12.3 10.2 8.1 21.5 10.7 4.9 20.2 4.2 11.5 6.4 5.2 18.9 13.7 8.9 10.1 7.0 15.2 12.0 8.2 9.4 9.8 6.3 9.6 10.7 11.2 9.6 7.0 10.9 12.2 8.7 34.6 8.8 8.8 6.7 9.2 6.1 14.2 30.2 16.1 19.3 16.2 14.4 33.4 15.2 22.1 30.6 56.6 54.6 22.2 18.7 12.2 33.8 11.2 33.1 84.3 73.9 15.7 37.3 34.0 29.9 16.3 1.9 24.9 12.3 46.7 16.9 17.1 16.4 15.5 44.1 30.4 16.2 25.4 15.6 22.1 24.3 1.8 28.4 28.4 8.5 38.7 12.2 29.9 15.2 14.8 26.5 34.1 50.6 25.8 18.0 22.7 57.3 9.7 26.8 34.6 13.3 8.7 ZRSR2 "U2AF1-RS2, U2AF1L2, URP, ZC3H22" ENSG00000169249 "Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2" Q15696 X 15790472-15823260 "Cancer-related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "prognostic favorable (7.96e-4)" "unprognostic (1.54e-2)" "unprognostic (7.31e-2)" "prognostic favorable (8.50e-5)" "unprognostic (8.08e-2)" "unprognostic (1.69e-1)" "unprognostic (6.14e-3)" "unprognostic (5.72e-3)" "unprognostic (8.46e-2)" "unprognostic (3.47e-3)" "unprognostic (6.90e-2)" "unprognostic (2.85e-2)" "prognostic unfavorable (4.87e-5)" "unprognostic (8.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.65e-2)" "prognostic favorable (2.97e-4)" 11.4 9.7 16.7 13.4 21.7 32.5 14.2 22.5 22.1 20.7 13.6 7.6 11.2 9.1 17.1 17.7 10.9 11.8 8.8 12.8 16.1 14.4 11.5 8.2 13.9 21.7 18.1 11.6 16.7 9.2 15.7 31.1 9.8 16.0 11.8 10.9 9.4 10.6 10.6 31.7 12.3 12.4 14.5 20.1 21.1 9.5 4.8 17.5 7.9 12.8 5.6 16.5 21.8 16.7 23.8 17.8 22.0 18.8 10.2 20.3 7.6 9.5 6.4 11.0 10.3 15.6 13.5 4.4 7.9 7.4 7.7 7.8 7.5 7.9 10.9 13.6 7.3 19.7 9.4 10.6 13.7 8.0 8.1 14.0 7.2 15.1 7.0 10.7 16.4 16.9 6.7 12.6 14.1 23.0 15.1 13.3 10.5 11.3 10.8 9.2 11.7 8.7 17.3 14.0 5.0 8.9 10.1 15.4 11.1 9.1 7.6 7.7 8.4 18.5 16.5 11.5 15.7 13.0 9.5 9.3 7.7 5.5 20.2 7.4 9.2 7.7 10.4 5.9 11.9 9.9 22.0 18.8 16.6 13.5 16.6 13.1 21.6 17.1 18.0 10.9 23.8 20.3 14.8 21.0 10.2 15.6 17.8 16.0 7.6 16.7 21.7 22.5 22.1 16.1 14.4 18.1 11.6 16.0 17.5 8.9 19.5 19.6 9.7 10.1 13.0 20.2 5.1 25.4 17.0 15.7 13.7 6.1 19.9 11.9 1.0 13.5 12.1 0.0 12.9 6.7 11.0 6.3 31.2 12.5 17.3 7.9 16.1 8.6 25.9 1.1 12.7 29.4 11.8 22.6 11.2 9.0 11.1 9.1 15.6 11.0 18.4 19.4 17.9 3.8 3.8 9.3 6.1 30.8 11.5 6.5