Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205744 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 4.5;Cholangiocytes: 5.1;Sertoli cells: 6.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 3.0 3.4 3.0 2.8 5.6 2.3 3.0 8.8 4.9 6.8 4.7 3.1 7.8 3.3 9.8 11.3 6.9 5.2 2.4 3.5 3.0 3.4 4.2 7.1 2.8 2.6 4.5 1.6 15.5 8.1 5.1 3.9 2.0 6.3 4.5 3.2 6.8 7.0 5.3 9.0 4.8 3.7 6.6 2.9 3.7 5.1 1.4 4.3 2.4 3.4 6.5 3.4 4.3 5.7 0.4 0.2 0.0 0.3 2.0 1.0 0.1 3.0 2.2 5.8 4.6 2.2 2.2 4.6 1.4 1.2 2.1 1.3 7.2 1.0 5.7 1.9 2.9 1.6 4.2 12.2 4.0 2.0 2.6 2.4 3.5 4.5 4.6 1.6 7.4 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.5 5.3 5.8 1.1 3.5 4.8 4.0 15.4 3.8 4.3 11.5 9.4 4.1 1.0 0.9 2.6 3.9 3.6 4.9 1.9 5.0 1.6 2.1 0.8 2.6 5.9 6.6 1.9 3.0 2.0 4.4 1.2 8.4 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.4 0.0 0.4 0.0 0.3 1.0 0.0 0.0 2.0 0.0 0.2 0.9 0.1 3.0 5.6 8.8 4.9 3.0 3.4 4.5 1.6 6.3 4.3 0.0 0.0 0.0 0.6 1.9 4.5 2.3 5.1 0.0 0.0 0.0 2.0 0.8 0.0 1.0 0.0 1.0 0.5 0.0 1.4 0.6 0.8 0.4 0.0 1.9 0.3 0.0 1.2 2.5 1.5 0.0 2.3 0.1 1.7 0.0 0.9 0.2 0.5 0.0 3.9 0.6 0.7 6.5 1.2 0.0 0.2 2.3 0.6 0.5 1.3 0.7 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC, WNT signaling pathway regulator" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.9" "Cell type enhanced" "Detected in many" 8 "Bipolar cells: 169.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 7.2 5.4 40.9 6.4 21.7 8.5 6.3 19.1 39.7 6.8 7.1 10.3 2.0 6.6 6.3 3.9 8.4 5.0 5.5 7.4 37.9 12.9 6.9 6.2 6.7 5.6 23.6 20.7 7.6 4.6 13.8 7.2 5.5 39.1 5.9 6.9 4.0 4.0 4.9 7.0 6.1 8.8 8.1 19.1 6.2 5.4 5.3 20.6 3.6 6.5 2.7 6.2 6.2 3.9 3.8 3.0 12.9 2.9 3.0 3.4 1.1 8.3 7.7 12.9 9.4 10.6 8.9 5.3 13.6 6.5 7.6 9.0 6.1 6.8 16.2 13.2 17.3 11.7 6.9 13.2 11.1 12.5 9.7 9.0 12.3 11.2 4.7 5.2 6.2 6.7 7.4 7.7 12.8 8.5 5.3 10.5 7.8 15.1 5.6 10.9 5.8 7.1 3.1 4.6 4.6 2.8 6.0 16.0 7.9 7.0 10.7 13.1 7.9 12.9 5.0 5.5 5.5 7.0 5.1 16.7 15.4 7.4 15.1 10.3 4.4 6.6 6.4 8.5 11.5 8.6 10.4 2.9 5.0 3.4 1.4 2.9 3.1 1.8 2.1 2.3 3.8 2.9 2.8 12.9 3.0 2.5 3.0 1.6 1.1 40.9 21.7 19.1 31.4 37.9 12.9 23.6 20.7 39.1 20.6 47.6 17.6 10.8 8.3 10.0 169.9 48.4 12.7 20.1 26.1 0.0 62.8 4.4 0.0 16.7 6.3 21.0 24.6 0.0 17.0 5.3 10.2 10.3 18.5 12.1 13.8 74.7 26.4 28.8 14.9 4.4 16.4 14.8 16.9 19.0 15.5 21.8 16.3 25.9 18.4 4.2 37.9 38.8 14.3 14.9 26.7 10.2 2.4 10.7 14.2 7.6 APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.1" "Cell type enhanced" "Detected in many" 8 "Basal keratinocytes: 4.7;Ductal cells: 7.3;Melanocytes: 6.8;Pancreatic endocrine cells: 5.7;Urothelial cells: 9.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "memory B-cell: 10.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 60.7;Karpas-707: 68.8" "HPA056980, HPA066719" Approved Nucleoplasm NA NA Nucleoplasm "HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (2.92e-2)" "prognostic favorable (2.58e-5)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.47e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.04e-1)" 1.6 2.3 0.3 4.4 2.2 20.1 1.4 0.3 1.2 2.3 9.9 0.7 0.3 5.8 2.0 2.4 4.6 1.2 2.2 1.6 0.6 0.2 3.6 0.9 2.5 4.3 0.3 0.3 1.7 5.7 0.4 0.3 6.4 0.8 2.1 10.0 1.3 4.8 0.3 4.1 1.9 8.8 1.0 0.7 10.4 3.8 2.0 0.3 5.9 3.3 0.3 12.0 2.0 2.4 10.2 0.8 1.7 5.8 2.2 3.8 5.9 60.7 6.8 2.6 16.4 0.3 1.5 4.5 5.6 4.9 10.8 14.2 13.0 11.1 0.6 5.1 5.6 15.9 26.1 0.3 1.1 10.9 21.9 0.6 17.5 1.5 3.4 0.1 14.5 10.6 0.6 0.1 11.2 0.5 2.2 4.1 0.0 9.8 68.8 16.6 1.6 0.0 8.1 0.0 5.8 6.1 0.4 26.3 21.8 2.2 10.2 0.4 0.0 0.0 0.0 3.7 0.4 8.1 4.2 2.5 11.9 20.8 1.8 0.1 15.3 4.2 0.0 8.5 16.2 24.1 0.5 1.3 0.0 0.3 5.8 0.0 10.2 0.8 0.5 0.8 3.2 0.0 0.4 1.7 2.2 1.8 0.1 3.8 5.9 0.3 2.2 0.3 1.2 0.6 0.2 0.3 0.3 0.8 0.3 0.0 1.7 0.8 2.2 4.7 0.0 0.2 0.0 1.4 2.3 0.0 0.0 0.3 0.0 7.3 0.0 0.0 0.5 0.0 1.6 1.9 0.4 1.2 0.0 0.0 1.8 0.0 0.0 0.0 1.6 0.0 0.0 1.6 6.8 1.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.7 0.0 0.6 9.5 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782110 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 18.6 18.4 17.4 24.9 17.0 33.8 27.8 23.6 19.1 20.3 23.7 21.7 23.9 15.8 24.1 17.3 23.2 20.6 21.9 15.5 14.8 12.8 13.7 15.9 18.8 35.6 20.3 19.2 24.1 23.9 27.5 15.8 19.3 17.2 16.5 16.4 18.9 21.4 23.1 22.6 20.6 20.7 18.4 15.4 25.9 19.5 16.5 19.8 57.3 24.8 14.2 24.5 24.4 20.4 4.3 5.3 7.4 3.3 4.7 5.1 3.5 19.2 18.3 25.9 27.0 7.5 7.2 12.2 9.0 7.9 12.4 8.8 13.3 13.0 27.2 7.9 11.7 7.8 11.7 22.5 10.0 14.5 33.6 8.8 23.1 11.9 8.9 6.2 34.2 7.4 8.3 7.1 14.6 10.5 6.9 10.6 19.7 27.6 30.5 8.0 9.1 28.8 13.3 27.4 12.5 8.5 30.1 17.1 15.4 7.7 13.0 24.3 20.0 15.8 13.4 10.9 15.0 3.9 19.4 18.7 13.3 12.9 12.4 14.6 14.5 19.1 12.5 8.1 21.9 11.7 0.4 3.3 2.9 4.0 2.9 5.1 4.3 3.2 4.9 3.1 4.3 4.0 4.4 7.4 4.7 2.8 5.3 1.5 3.5 17.4 17.0 23.6 19.1 14.8 12.8 20.3 19.2 17.2 19.8 56.6 36.8 33.6 18.1 65.3 60.2 31.1 28.1 25.4 28.4 36.6 49.1 31.8 1.7 31.8 14.2 37.2 28.4 0.0 32.5 32.1 42.6 39.3 56.9 53.9 43.0 69.9 45.7 51.0 93.5 7.5 35.6 45.4 38.8 34.3 56.1 31.2 40.3 31.6 39.3 14.5 37.1 51.8 27.2 46.0 55.3 82.4 30.7 41.2 46.0 27.7 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 198.3;Rod photoreceptor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.7 3.9 7.7 4.1 10.0 14.6 2.0 6.1 6.8 3.5 5.9 4.8 6.5 9.6 9.1 4.9 5.6 4.1 5.8 5.1 5.5 7.7 3.4 8.7 4.8 4.8 5.3 10.5 9.4 9.4 3.2 5.4 10.4 7.7 7.4 8.2 8.4 6.6 6.9 2.0 7.1 9.7 6.3 4.1 3.9 5.6 5.3 15.1 4.0 5.5 5.2 6.4 7.1 3.3 10.5 7.1 5.0 5.9 11.5 8.8 4.9 5.0 5.7 4.4 4.6 48.5 5.8 11.5 9.8 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 35.7 21.0 122.7 17.4 11.2 101.7 35.4 10.2 13.4 19.4 21.0 198.3 14.8 5.0 7.7 12.8 18.8 4.9 0.0 10.6 10.5 26.4 9.5 12.7 21.2 26.0 57.2 19.5 36.8 82.2 2.7 36.5 48.1 25.3 9.0 15.9 35.9 7.6 10.5 26.2 10.3 196.6 25.8 17.3 18.7 33.6 10.8 3.5 111.7 11.7 9.9 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352673 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 10.8 8.3 13.7 18.9 17.1 28.1 21.0 26.4 13.6 10.4 15.8 12.7 9.4 17.3 12.6 8.5 14.1 10.7 12.7 11.0 11.5 7.7 9.8 9.6 13.6 13.4 15.6 10.6 13.3 17.7 11.1 11.9 8.4 13.9 11.4 10.2 9.6 13.9 9.5 17.7 16.9 17.6 18.9 9.6 15.1 15.2 9.6 14.6 17.5 12.7 7.5 14.5 11.9 22.9 1.8 1.4 5.5 1.1 3.6 10.4 2.4 9.6 14.0 7.5 13.2 5.6 5.2 15.8 6.5 6.0 9.1 7.8 20.6 11.3 15.0 10.1 6.7 10.9 13.9 11.7 10.2 4.1 14.7 19.2 9.7 11.8 14.9 9.6 11.1 10.8 5.1 17.8 9.3 11.5 8.0 6.0 11.0 24.1 8.3 4.1 25.8 12.0 7.7 17.1 11.7 8.6 22.7 6.8 20.8 6.8 5.7 17.1 10.5 12.4 13.9 20.5 5.9 9.2 14.2 6.7 9.0 9.7 10.3 9.4 9.6 9.3 18.3 4.3 7.4 8.8 1.4 1.1 5.5 10.4 0.9 9.5 1.8 3.0 7.0 0.8 1.6 3.2 4.3 3.2 3.6 0.7 1.4 3.0 2.4 13.7 17.1 26.4 13.6 11.5 7.7 15.6 10.6 13.9 14.6 3.0 11.3 5.2 5.3 16.4 4.9 5.0 5.1 6.7 6.8 3.5 0.0 3.1 0.0 6.1 1.0 6.7 18.6 0.0 6.1 20.3 5.9 9.4 10.4 4.7 6.5 4.8 10.4 4.3 7.5 1.3 4.9 5.9 10.1 3.6 14.5 3.7 8.8 11.9 4.6 2.1 5.4 12.9 5.3 4.4 7.6 13.2 3.1 7.7 11.8 8.7 BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 46.0;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" 16 "granulocytes: 530.1;monocytes: 1925.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "memory B-cell: 32.9;naive B-cell: 32.9" "Group enriched" "Detected in many" 10 "B-cells: 32.9;T-cells: 17.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.4;Daudi: 33.7;HDLM-2: 31.9;hTERT-HME1: 33.6;U-266/70: 22.5;U-266/84: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" 6.9 3.3 1.4 43.9 2.3 5.1 5.4 0.5 2.0 5.3 13.1 0.5 2.8 6.8 2.9 3.7 8.4 3.9 13.9 6.0 2.2 1.3 10.8 12.5 21.8 46.3 2.8 1.2 3.4 7.0 1.1 14.5 0.9 2.2 8.7 6.2 1.1 9.2 4.7 2.2 5.5 46.0 7.3 3.0 34.9 15.9 3.2 2.7 34.2 3.0 4.1 34.0 12.6 6.2 32.9 0.8 2.0 2.6 2.5 17.1 2.8 6.5 5.3 0.0 0.1 0.1 0.7 0.6 0.5 4.4 0.6 0.7 0.9 38.4 33.7 17.4 0.3 5.5 3.6 0.0 0.9 2.1 31.9 0.1 0.1 1.6 0.2 6.6 0.5 0.7 0.7 4.7 2.1 33.6 1.2 0.1 2.7 0.1 0.0 0.8 0.0 2.3 0.3 0.1 3.1 0.2 0.0 0.3 1.7 8.7 3.4 0.0 0.1 0.5 0.6 0.3 0.2 1.7 0.3 1.7 7.3 0.8 0.4 6.7 22.5 19.2 11.9 1.3 1.9 0.9 2.0 0.9 0.4 1.4 2.2 2.5 32.9 10.7 3.5 0.8 32.9 7.5 2.2 0.5 2.5 2.6 0.3 17.1 2.8 1.4 2.3 0.5 2.0 2.2 1.3 2.8 1.2 2.2 2.7 134.0 68.1 285.1 318.0 89.9 0.3 12.0 76.5 30.8 73.9 38.4 0.0 1.7 6.6 193.4 1.3 50.1 284.0 46.7 153.8 0.5 71.9 371.3 530.1 3.4 11.1 0.0 14.5 7.4 18.1 1.3 4.6 71.9 182.2 1925.2 27.1 0.1 190.8 361.2 2.1 8.8 0.0 0.0 133.5 0.5 0.4 73.9 0.5 89.3 29.9 164.7 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1, DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Spermatocytes: 64.7;Spermatogonia: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 9.1;granulocytes: 9.7;monocytes: 12.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 4.8 4.3 6.0 9.6 11.3 15.3 5.1 12.9 10.6 5.4 9.2 3.4 6.8 4.3 5.4 5.5 9.1 5.5 3.3 6.5 6.6 5.3 4.2 7.7 4.9 13.0 7.5 5.9 5.1 4.7 4.2 11.0 5.3 10.5 4.1 10.4 3.7 5.4 7.4 7.3 8.3 6.7 5.5 9.2 5.9 5.1 17.6 7.0 10.9 15.6 7.3 14.6 5.5 5.6 2.0 9.1 9.7 12.7 1.4 1.3 10.7 15.7 25.6 14.1 11.2 2.3 5.2 13.8 18.6 8.0 15.6 14.9 15.5 12.3 36.4 3.4 7.1 18.5 18.3 19.1 10.4 26.2 16.6 14.0 17.1 20.1 13.4 0.5 30.5 14.9 1.4 1.7 23.5 7.5 4.0 8.1 17.0 25.8 15.6 14.7 10.5 25.5 10.1 7.7 10.6 6.8 17.6 29.7 14.9 5.8 15.3 9.7 10.4 14.3 4.7 7.0 10.0 12.6 14.1 5.2 14.0 11.4 18.1 19.3 7.3 17.8 28.0 11.3 18.1 14.6 4.6 12.7 1.8 1.3 4.0 1.3 1.1 1.3 1.0 9.1 2.0 1.2 1.3 9.7 1.4 1.5 1.4 0.4 10.7 6.0 11.3 12.9 10.6 6.6 5.3 7.5 5.9 10.5 7.0 0.0 3.2 5.2 3.8 2.6 8.3 10.4 7.6 13.4 5.7 1.8 21.6 7.0 0.0 2.6 11.1 2.9 1.0 0.0 1.0 17.5 2.9 2.4 8.1 16.1 8.6 11.1 0.0 5.5 4.0 5.2 2.3 5.3 0.0 3.6 3.7 2.8 1.6 3.1 1.4 0.8 21.1 6.5 1.4 64.7 61.1 1.9 3.3 2.5 3.5 2.5 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2, DNA repair associated" P51587 13 32315474-32400266 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease mutation, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 16.9" "Group enriched" "Detected in many" 4 "Erythroid cells: 23.3;monocytes: 31.5;Spermatocytes: 75.1;Spermatogonia: 82.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 2.4 1.0 0.6 13.8 0.6 11.6 3.2 0.6 0.6 1.8 4.0 0.2 0.2 1.4 1.5 2.7 3.0 1.0 0.7 2.1 0.6 0.7 1.0 1.4 3.5 5.3 0.7 0.5 1.4 3.3 0.4 0.7 7.0 0.8 0.9 2.0 0.1 1.8 0.3 3.3 1.8 3.2 0.8 2.1 6.6 1.5 16.9 0.1 23.2 0.9 4.8 4.2 1.3 1.7 1.3 1.9 0.4 0.2 1.5 0.8 0.0 4.0 3.5 6.1 4.6 0.6 1.6 6.2 4.3 2.7 5.0 4.6 8.3 5.3 14.2 2.9 2.1 6.9 5.4 5.0 2.5 9.7 9.2 2.7 9.0 2.2 3.2 0.2 12.8 4.5 0.4 0.3 9.2 6.4 0.5 4.1 7.2 5.9 4.9 5.7 4.6 10.3 7.6 7.2 4.6 1.9 10.1 15.7 2.7 1.3 4.3 2.3 4.4 5.2 2.3 2.1 2.2 2.7 6.4 3.2 5.8 6.2 6.4 6.0 1.9 2.9 7.3 3.0 5.1 5.5 0.1 0.2 0.2 0.3 0.2 0.1 0.9 0.4 0.2 0.2 1.3 0.6 0.8 0.4 1.5 0.2 1.9 0.4 0.0 0.6 0.6 0.6 0.6 0.6 0.7 0.7 0.5 0.8 0.1 8.9 1.6 1.9 2.8 2.3 0.0 1.6 0.0 4.0 2.3 0.0 0.0 9.1 0.0 1.8 4.3 3.6 1.0 23.3 1.4 9.1 3.5 0.6 3.5 0.8 8.2 0.0 1.2 2.5 6.7 2.5 2.0 13.2 3.3 31.5 3.0 0.2 1.1 1.5 1.1 0.6 0.0 12.9 2.0 75.1 82.4 1.1 4.6 3.8 5.3 1.4 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967753-21995301 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 22.6;pituitary gland: 39.3" "Cell type enhanced" "Detected in many" 13 "Early spermatids: 178.1;Late spermatids: 275.2;Pancreatic endocrine cells: 259.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 22.6" "Group enriched" "Detected in many" 8 "B-cells: 7.2;T-cells: 22.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 50.2;HEK 293: 56.9;HeLa: 53.2;SK-MEL-30: 53.1" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 5.4 8.6 2.9 4.5 3.9 1.8 5.3 1.7 3.1 1.2 2.5 4.4 0.1 1.2 1.2 1.9 6.3 3.0 2.6 0.7 1.7 1.0 0.9 1.2 3.0 3.0 3.6 1.6 1.5 1.5 8.5 39.3 6.7 5.0 1.9 1.1 1.2 2.4 2.9 0.9 1.3 3.7 1.0 3.0 8.9 6.0 13.0 1.9 3.9 1.4 3.0 14.0 2.7 1.5 7.2 0.2 0.8 1.8 0.4 22.6 2.2 2.1 0.0 0.3 14.1 0.1 0.1 6.1 2.3 0.0 19.7 35.1 3.5 50.2 7.2 32.3 1.6 0.0 6.0 5.9 36.5 15.9 31.0 56.9 0.0 53.2 2.3 1.5 3.6 3.0 3.8 0.0 19.8 11.0 42.3 2.0 0.0 0.0 33.0 18.0 0.1 0.3 0.0 0.4 4.0 29.3 0.0 13.4 26.5 4.0 0.0 33.1 2.3 38.2 6.3 53.1 1.7 7.5 0.1 6.6 0.1 0.4 0.0 0.1 14.7 8.3 29.5 0.0 9.5 0.1 0.8 1.3 0.2 6.2 0.6 9.7 7.2 8.0 11.0 0.2 7.0 0.5 4.7 0.4 0.4 1.8 0.0 22.6 2.2 2.9 3.9 1.7 3.1 1.7 1.0 3.6 1.6 5.0 1.9 0.0 0.0 1.5 0.7 1.5 0.2 4.0 0.0 14.7 1.2 10.4 0.0 20.9 0.0 32.4 178.1 2.2 6.9 0.0 22.9 52.3 3.6 10.0 4.6 0.0 6.6 0.0 68.2 0.6 8.2 275.2 2.8 1.8 8.5 26.2 6.2 0.8 259.8 10.5 1.8 0.0 0.0 0.0 1.0 5.7 4.1 0.4 7.7 12.5 2.3 34.0 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974633 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 70.0;Sertoli cells: 84.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 53.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 42.1 12.6 5.9 10.7 7.9 14.9 31.7 4.3 5.7 13.1 13.0 8.7 7.7 6.6 17.1 13.9 11.5 8.4 13.7 20.1 5.7 3.1 7.4 3.3 7.9 11.0 13.7 5.3 22.5 9.4 23.1 5.7 3.1 3.9 10.3 5.7 6.0 5.4 12.2 9.2 8.5 7.9 15.1 7.5 8.5 5.3 5.3 8.9 54.2 8.0 4.9 9.8 17.4 21.7 3.4 7.4 12.2 2.5 6.0 14.1 3.8 14.0 5.8 1.1 19.4 20.0 2.9 0.2 13.4 13.6 22.5 19.8 0.3 4.8 27.6 12.1 11.4 8.2 1.7 13.0 1.7 11.1 16.7 17.5 20.9 44.3 3.5 1.0 14.5 9.6 1.0 0.3 6.1 2.6 8.5 5.9 22.9 9.4 0.0 13.0 3.5 18.7 7.0 0.0 5.3 14.2 22.3 18.3 0.0 7.1 5.9 9.8 23.0 18.3 12.8 4.3 0.1 6.3 49.3 4.7 25.8 10.0 15.6 0.2 28.3 26.9 22.7 0.0 53.0 22.8 12.2 2.5 11.0 5.2 1.4 6.0 3.4 7.7 6.8 6.1 1.9 4.3 4.1 0.2 6.0 0.6 7.4 14.1 3.8 5.9 7.9 4.3 5.7 5.7 3.1 13.7 5.3 3.9 8.9 0.0 4.6 5.3 2.5 9.0 4.2 12.5 2.5 2.7 2.3 3.5 15.7 1.1 14.9 3.3 3.6 5.3 3.9 70.0 3.1 11.0 20.6 2.5 16.1 6.0 22.5 4.8 8.1 17.2 19.7 5.3 36.5 11.2 6.8 24.4 4.8 27.8 4.0 4.0 44.9 26.6 9.7 84.1 18.6 5.1 6.8 9.8 1.6 33.8 3.9 1.0 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "Fanconi anemia complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6;testis: 28.8" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 23.3;Spermatocytes: 22.3;Spermatogonia: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 2.1 2.0 2.2 16.5 3.7 17.1 1.7 5.7 6.6 1.7 5.1 1.1 0.6 5.0 1.7 3.1 6.6 1.9 1.6 1.7 1.8 1.4 2.1 5.8 3.3 11.1 1.3 2.7 1.6 1.8 2.3 1.9 11.2 2.4 1.7 6.3 1.5 2.2 0.5 0.7 5.0 5.4 2.0 1.6 6.9 3.5 28.8 0.8 20.6 1.7 4.6 17.6 2.9 2.5 7.4 6.5 9.9 9.2 7.5 9.5 4.2 9.3 14.4 17.3 15.1 1.1 2.2 13.2 11.7 6.4 19.8 8.3 12.6 15.6 23.1 5.5 4.0 6.6 14.5 11.6 8.7 20.9 5.4 19.5 6.8 18.5 25.8 0.7 6.9 7.5 0.7 0.9 16.0 5.1 2.8 6.2 11.7 16.3 7.1 10.3 21.7 13.8 30.0 11.2 12.9 9.0 25.2 13.9 4.2 4.9 8.9 15.5 8.4 17.5 5.2 2.2 10.4 9.4 12.5 4.6 15.9 16.8 8.8 12.2 6.4 7.5 22.9 7.5 15.5 15.1 2.6 7.9 9.9 4.7 8.8 3.3 7.4 2.8 4.1 6.5 5.5 0.7 3.0 9.8 7.5 9.2 0.4 9.5 4.2 2.2 3.7 5.7 6.6 1.8 1.4 1.3 2.7 2.4 0.8 0.0 0.6 13.1 1.4 3.1 8.8 1.6 0.0 1.4 3.4 15.7 9.8 10.9 1.7 1.6 5.3 0.8 2.0 23.3 1.4 7.5 1.3 0.5 2.3 4.0 7.7 3.2 1.7 7.4 4.3 3.5 1.4 6.3 0.0 0.0 6.1 1.4 1.5 0.0 0.0 6.8 7.2 0.0 1.0 22.3 33.2 1.6 21.2 3.2 6.3 2.1 FANCC "FA3, FAC, FACC" ENSG00000158169 "Fanconi anemia complementation group C" Q00597 9 95099054-95426796 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 29.7" "Group enriched" "Detected in many" 5 "Early spermatids: 190.4;Late spermatids: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 10.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.4" "Cell line enhanced" "Detected in all" "RH-30: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017793, HPA030771" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB017793: , HPA030771: AB_2673604" "unprognostic (1.48e-2)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-2)" "unprognostic (3.41e-3)" "unprognostic (1.26e-2)" "unprognostic (7.45e-3)" "unprognostic (1.37e-1)" "unprognostic (8.00e-3)" "unprognostic (3.19e-2)" "prognostic favorable (6.03e-6)" "unprognostic (2.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.71e-2)" 4.9 2.7 4.3 8.6 7.0 3.6 4.6 29.7 7.7 4.6 6.4 4.9 5.1 7.1 6.3 4.1 4.5 3.6 5.2 3.2 4.0 2.7 10.0 25.7 6.7 3.7 7.3 1.6 3.3 5.4 2.9 12.1 4.3 6.7 4.4 6.1 4.0 4.0 4.2 4.5 7.7 8.1 2.9 6.4 3.4 4.4 19.6 7.3 7.9 4.3 3.2 6.0 3.5 4.0 1.0 1.3 10.4 1.7 0.3 1.5 0.7 13.6 9.2 12.2 10.6 1.2 3.2 7.7 5.9 3.9 9.5 8.8 10.5 5.8 7.8 4.2 4.3 7.3 16.7 12.3 5.2 5.2 7.4 5.8 6.1 10.4 5.4 2.0 6.1 6.8 2.7 2.2 7.6 3.4 2.6 5.2 7.6 9.1 3.4 6.8 9.6 5.7 3.5 5.8 14.5 5.2 12.2 31.5 3.6 3.9 3.5 17.7 9.4 11.3 4.0 3.4 6.4 4.2 5.1 2.5 8.3 12.2 9.1 8.4 3.6 6.6 4.1 4.5 5.6 9.8 10.4 0.4 0.0 1.3 0.8 1.3 1.0 0.7 1.5 0.4 1.0 1.2 1.0 0.1 0.3 1.7 1.3 1.3 0.7 4.3 7.0 29.7 7.7 4.0 2.7 7.3 1.6 6.7 7.3 3.0 2.1 0.0 2.3 2.3 5.4 1.6 5.1 1.4 3.4 0.0 3.9 2.3 1.7 4.1 190.4 4.3 3.3 0.0 3.6 4.0 2.0 2.5 5.7 25.1 1.8 9.5 0.0 4.3 2.7 63.3 6.1 1.3 1.7 3.6 4.5 2.6 3.4 0.0 2.1 7.7 4.2 0.0 1.6 13.0 10.6 2.4 1.9 1.0 3.8 2.5 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "Fanconi anemia complementation group D2" Q9BXW9 3 10026414-10101930 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.4;testis: 23.3" "Cell type enhanced" "Detected in many" 9 "Erythroid cells: 46.7;Spermatocytes: 55.1;Spermatogonia: 32.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 46.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 2.0 1.3 0.8 10.3 2.6 12.2 2.4 1.6 2.7 1.7 2.9 1.1 1.0 2.2 2.2 1.8 4.7 2.4 2.5 1.1 0.8 0.9 2.3 1.0 2.4 9.5 1.3 1.2 3.5 3.5 0.6 1.1 5.3 1.4 2.2 4.9 1.6 3.3 0.4 3.0 3.3 6.2 1.2 2.0 7.3 2.4 23.3 1.6 24.4 1.6 5.6 14.6 2.2 2.4 6.8 3.7 5.3 2.6 2.1 2.9 1.0 8.7 9.3 17.8 5.0 0.9 1.4 46.0 8.0 3.6 11.5 9.4 6.9 8.7 17.1 3.8 2.6 9.5 7.6 18.3 6.2 11.5 8.1 12.4 23.3 14.3 6.6 0.1 17.3 14.6 0.4 1.0 13.0 7.2 1.6 6.9 14.7 14.2 19.6 8.7 10.0 14.4 6.7 21.4 6.7 6.5 15.8 14.5 12.1 4.0 9.8 4.9 9.8 9.8 7.7 3.1 13.5 11.8 11.0 4.0 9.6 11.0 5.8 11.6 8.3 16.3 28.9 5.5 17.8 16.3 5.3 1.4 3.7 1.5 1.0 1.3 4.9 2.0 1.2 0.9 6.8 2.5 1.9 3.3 2.1 2.6 3.7 2.9 1.0 0.8 2.6 1.6 2.7 0.8 0.9 1.3 1.2 1.4 1.6 0.0 0.3 9.7 2.8 4.0 2.8 1.6 0.0 1.4 1.2 1.8 9.8 6.6 0.0 1.6 4.4 1.5 0.7 46.7 2.9 12.7 1.3 2.2 1.1 1.0 5.0 0.0 1.2 3.7 3.4 5.6 2.0 5.2 3.3 7.2 2.0 0.8 1.4 2.8 1.4 0.5 5.8 19.4 0.8 55.1 32.4 2.4 5.8 3.8 5.0 2.3 FBXO11 "FBX11, UBR6" ENSG00000138081 "F-box protein 11" Q86XK2 2 47789316-47905793 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002690 Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA002690: AB_1848448" "unprognostic (1.18e-1)" "unprognostic (8.65e-3)" "unprognostic (3.93e-2)" "unprognostic (2.05e-2)" "unprognostic (7.92e-2)" "unprognostic (1.42e-1)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-2)" "unprognostic (9.82e-2)" "unprognostic (5.77e-2)" "unprognostic (2.33e-2)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" 18.0 13.8 18.6 15.7 18.8 17.5 26.1 42.2 31.7 21.3 15.3 12.7 15.1 10.4 28.9 16.8 14.5 16.3 15.0 14.1 16.9 13.6 14.3 17.0 22.3 15.0 17.4 21.7 28.9 12.4 25.2 14.4 14.5 19.7 15.3 13.3 12.0 15.6 16.5 22.9 14.5 13.5 19.9 16.4 14.5 13.3 25.1 16.0 14.6 17.3 9.8 17.2 19.3 21.9 4.7 4.3 8.2 2.7 4.8 6.6 2.0 25.5 13.3 31.9 27.2 22.4 21.1 19.0 17.9 24.6 16.7 16.5 11.2 13.0 16.5 23.4 25.1 20.8 12.7 21.8 18.9 24.7 11.0 10.8 15.4 10.9 17.8 21.5 16.0 16.4 20.6 21.3 14.9 25.2 26.6 21.4 8.3 15.0 17.1 20.5 12.3 15.3 15.6 19.4 16.9 13.1 20.0 29.6 12.3 23.9 20.9 22.5 26.6 16.9 15.9 26.1 24.7 7.4 13.7 23.1 20.8 19.2 13.9 19.6 14.8 7.7 30.1 14.1 15.1 21.1 8.2 2.3 4.3 3.8 2.7 3.8 4.7 3.4 4.1 3.1 3.6 6.6 4.1 4.1 4.8 2.4 4.3 3.6 2.0 18.6 18.8 42.2 31.7 16.9 13.6 17.4 21.7 19.7 16.0 14.9 36.6 13.7 38.4 59.5 42.4 7.8 12.7 37.5 23.9 17.4 31.4 16.6 10.0 15.5 22.2 26.9 15.8 0.0 13.2 13.7 43.3 34.1 27.8 17.0 21.7 52.4 23.0 29.4 42.9 29.9 27.9 40.9 33.7 17.2 16.7 30.9 20.6 14.4 37.4 11.3 39.1 19.4 35.3 51.9 40.4 51.6 30.1 26.6 16.9 57.8 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536063 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 60.1;skin 1: 45.0" "Cell type enhanced" "Detected in many" 7 "Basal keratinocytes: 179.3;Suprabasal keratinocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 9.2 6.8 27.0 8.9 27.9 11.1 9.8 27.2 60.1 5.5 6.1 3.6 3.8 4.9 6.0 18.3 9.8 10.6 6.3 10.9 21.4 10.1 4.1 7.3 6.9 9.8 9.1 40.5 6.4 8.0 6.4 7.3 6.2 37.2 5.1 6.9 2.8 7.6 5.3 15.8 45.0 6.5 6.1 6.4 10.1 8.0 13.7 5.7 6.5 6.8 10.6 12.3 7.9 6.5 2.9 2.2 16.6 3.4 7.8 5.0 1.3 4.9 4.0 10.3 7.5 7.2 5.2 8.6 7.2 6.6 4.5 4.2 8.0 6.4 12.9 2.0 6.9 3.4 3.0 8.9 16.2 6.3 7.3 4.2 6.0 4.9 5.7 7.3 14.6 5.5 8.2 25.8 7.7 13.1 4.7 7.8 10.5 9.4 13.8 5.6 7.0 16.8 5.8 5.0 4.2 3.2 16.9 4.4 2.5 5.5 8.6 6.6 5.7 4.6 6.3 3.9 12.2 3.4 6.9 8.2 6.1 6.9 3.1 4.0 38.0 21.7 12.6 4.9 4.8 4.3 16.6 3.1 1.7 5.0 3.4 3.3 2.9 3.7 3.2 1.8 2.4 3.9 3.2 5.5 7.8 2.5 2.2 3.3 1.3 27.0 27.9 27.2 60.1 21.4 10.1 9.1 40.5 37.2 5.7 8.9 18.5 27.6 32.1 179.3 67.8 54.1 7.6 8.1 13.6 8.7 29.5 9.7 3.3 11.6 13.1 26.4 13.5 0.0 11.7 33.1 24.6 28.4 15.1 15.6 9.4 11.1 13.9 17.8 16.2 7.4 14.1 20.2 27.0 16.2 11.7 30.1 15.8 15.8 10.6 6.0 40.5 12.9 25.6 57.9 80.3 152.9 26.1 34.6 11.3 48.9 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985895 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 262.7" "Cell type enhanced" "Detected in many" 10 "Fibroblasts: 127.3;Muller glia cells: 96.7;Syncytiotrophoblasts: 124.3" "Cancer enhanced" "Detected in all" "liver cancer: 269.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.0;naive CD8 T-cell: 3.5;NK-cell: 1.7" "Group enriched" "Detected in many" 12 "NK-cells: 1.7;T-cells: 5.0" "Group enriched" "Detected in some" 5 "HAP1: 54.2;Hep G2: 214.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 30.1 5.9 0.4 3.6 0.7 0.0 50.2 0.6 0.4 3.3 4.5 0.5 2.2 0.5 2.5 11.7 2.0 3.4 9.2 8.0 0.4 1.1 21.2 1.1 37.0 1.9 1.6 0.4 6.0 4.6 0.3 16.9 262.7 1.6 3.6 1.0 6.3 3.8 2.3 4.1 5.5 1.8 3.3 2.1 0.9 4.0 2.1 0.3 2.3 7.2 11.2 3.0 7.6 8.0 0.0 0.2 0.0 0.0 1.7 5.0 0.6 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 54.2 0.0 0.0 0.0 2.5 0.0 0.1 214.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 14.8 0.7 1.8 4.4 0.0 0.0 0.0 26.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.2 0.0 5.0 3.5 0.0 1.7 0.0 0.0 0.0 0.6 0.4 0.7 0.6 0.4 0.4 1.1 1.6 0.4 1.6 0.3 0.0 1.7 0.0 5.4 9.3 0.2 0.3 0.0 44.2 35.2 5.2 0.0 43.0 16.6 0.3 0.9 0.5 0.3 0.0 1.3 32.7 127.3 0.9 0.0 0.0 24.0 0.0 1.7 2.5 0.0 1.3 9.8 1.4 3.3 0.0 1.5 96.7 2.2 0.2 2.8 26.9 1.9 0.0 5.0 1.6 6.1 3.4 124.3 0.0 2.1 0.5 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 28.7;bone marrow: 55.2;lymphoid tissue: 86.7" "Cell type enhanced" "Detected in many" 11 "B-cells: 46.7;Kupffer cells: 47.2;Macrophages: 43.8;monocytes: 70.3;T-cells: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 26.9;HDLM-2: 45.8;HMC-1: 42.9;JURKAT: 26.3;MOLT-4: 33.5;REH: 36.3;U-698: 68.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 3.5 1.5 2.9 25.5 3.8 55.2 2.3 0.7 1.8 1.6 3.6 2.8 0.8 2.4 1.6 2.1 2.2 2.4 2.9 1.6 3.4 1.8 2.5 2.3 8.3 44.4 5.9 1.1 1.1 1.3 0.2 1.2 1.2 3.4 2.2 2.5 1.5 5.2 0.7 0.9 1.9 14.5 1.4 5.1 31.0 3.7 1.1 4.1 86.7 2.4 1.2 26.3 4.5 2.9 24.0 12.6 12.8 23.6 12.8 28.7 12.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 9.2 0.0 0.0 0.0 16.3 42.9 0.0 0.0 0.0 0.0 0.0 0.0 26.3 11.9 3.2 0.0 0.0 33.5 16.2 0.4 0.0 0.0 36.3 0.0 7.6 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.0 0.0 22.5 0.0 0.0 0.3 0.0 0.0 14.6 7.5 68.8 0.1 17.7 0.1 10.2 7.7 12.8 20.4 23.6 17.0 24.0 21.2 19.9 8.2 21.3 28.7 20.7 11.2 12.8 22.3 12.6 17.1 12.7 2.9 3.8 0.7 1.8 3.4 1.8 5.9 1.1 3.4 4.1 3.0 16.4 46.7 0.1 2.5 0.0 1.1 5.1 2.7 3.4 1.8 0.0 0.3 0.0 0.1 3.0 2.9 0.0 23.3 0.0 0.2 3.4 0.1 22.0 1.0 27.1 0.0 0.0 4.3 47.2 4.5 0.0 43.8 18.6 70.3 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 2.1 0.0 0.7 2.4 0.6 103.3 0.0 0.1 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873177-45112602 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 12.3 12.1 16.5 17.6 24.5 47.9 21.4 26.1 22.0 16.9 11.8 16.7 12.0 13.1 22.6 11.3 15.4 16.9 15.2 9.1 18.2 6.5 11.6 13.5 19.7 15.1 28.8 11.3 23.8 14.9 21.3 20.2 13.3 18.3 10.3 11.3 10.3 16.1 12.6 15.1 21.3 17.6 13.5 14.9 18.1 15.0 17.7 26.1 19.1 14.5 6.9 13.6 14.9 22.8 5.5 7.1 15.7 7.5 6.2 7.9 3.5 8.7 7.6 11.3 11.4 8.1 8.4 24.2 6.8 4.8 8.2 8.6 17.9 7.5 5.7 3.7 6.3 17.0 18.8 14.5 12.0 7.6 8.3 15.5 7.1 9.6 6.7 5.7 3.8 20.2 4.5 9.9 13.5 14.1 8.8 6.3 7.0 9.8 14.2 5.1 5.7 7.8 11.2 9.4 6.7 8.8 8.7 10.9 1.0 4.7 16.3 9.7 5.2 21.7 10.9 9.2 24.8 10.6 0.1 5.3 7.8 6.0 7.8 3.5 9.0 10.8 8.6 5.4 4.0 4.5 15.7 3.8 3.5 5.3 7.5 6.0 5.5 7.2 7.9 7.1 3.8 7.0 6.3 7.3 6.2 7.2 3.8 5.6 3.5 16.5 24.5 26.1 22.0 18.2 6.5 28.8 11.3 18.3 26.1 6.0 8.8 5.2 11.3 23.2 6.5 11.4 10.2 5.3 7.9 7.0 13.7 3.8 0.0 6.5 1.0 9.4 18.8 0.0 6.6 4.9 8.9 11.4 2.3 13.9 6.1 23.8 12.6 6.2 8.9 1.1 6.1 9.7 10.1 7.2 14.2 7.4 7.7 14.4 6.7 3.3 8.4 6.5 10.3 5.6 11.7 23.1 9.2 10.1 11.0 16.3 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131701 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7;thyroid gland: 14.9" "Group enriched" "Detected in some" 5 "Bipolar cells: 15.8;Early spermatids: 4.6;Late spermatids: 4.3" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "myeloid DC: 1.4;plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;HEK 293: 4.5;HeLa: 2.3;HSkMC: 2.2;U-138 MG: 4.9;U-87 MG: 2.6" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 63000 Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 4.8 4.5 17.6 1.3 14.1 1.2 2.6 23.2 25.7 1.4 1.3 6.5 0.0 1.2 1.3 6.8 1.3 1.9 1.4 1.6 18.3 9.3 2.2 1.6 1.4 1.2 10.8 16.7 3.0 1.2 1.1 12.7 1.2 12.8 3.5 1.3 0.1 2.5 3.8 10.5 1.7 1.3 1.3 8.2 1.2 1.5 1.9 10.6 0.0 14.9 0.0 1.3 1.2 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 4.2 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 1.0 0.2 0.2 0.6 4.5 0.0 2.3 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.4 1.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.2 0.0 0.0 0.4 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 17.6 14.1 23.2 21.3 18.3 9.3 10.8 16.7 12.8 10.6 0.0 0.0 0.0 0.3 0.2 15.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 0.8 0.0 0.3 0.1 0.1 0.3 0.0 0.0 0.0 0.6 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SuSa: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: AB_2684197" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 10.6 9.2 12.1 6.2 6.7 8.7 7.7 7.3 9.6 8.3 8.0 5.4 3.7 4.4 5.9 11.3 5.4 7.1 10.5 10.1 12.5 7.8 12.3 4.9 5.4 10.2 7.9 4.7 7.4 7.2 10.0 9.7 10.2 8.6 7.5 6.3 5.2 2.6 10.4 3.9 5.6 4.4 7.0 11.5 4.5 7.0 13.6 3.0 11.4 6.9 2.4 7.2 8.4 4.5 7.0 67.1 5.7 3.4 6.8 4.1 6.3 5.6 8.6 5.1 5.7 3.5 7.7 3.7 5.9 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 8.9 14.2 10.8 26.3 36.9 14.2 21.2 10.2 2.7 21.6 14.0 7.9 10.7 21.6 11.2 6.3 8.7 11.8 0.0 12.4 8.6 12.9 32.3 1.1 16.3 10.2 17.5 11.5 10.4 17.7 5.8 10.9 11.7 11.8 19.0 13.8 10.3 14.7 11.5 12.0 17.7 9.7 12.9 12.0 7.9 8.1 34.4 21.2 9.5 10.6 40.3 MEN1 ENSG00000133895 "Menin 1" O00255 11 64803510-64811294 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030342 Uncertain Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA030342: AB_10610138" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.66e-1)" "unprognostic (2.59e-1)" "unprognostic (1.42e-2)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.39e-2)" "prognostic favorable (6.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" 12.1 20.6 13.2 15.6 17.7 11.8 12.5 25.8 26.9 15.5 14.9 16.4 22.2 16.9 14.8 18.4 18.9 17.6 14.7 9.0 12.4 11.5 15.9 23.0 12.8 22.1 12.5 15.6 19.7 25.9 16.8 18.0 16.1 16.0 15.9 11.6 16.6 23.3 19.9 8.4 21.6 15.8 11.0 9.8 20.6 15.3 21.2 12.3 33.2 23.9 6.2 20.3 13.7 15.5 5.2 2.9 3.4 1.5 1.8 4.8 1.0 16.3 22.0 14.1 22.1 15.8 10.2 16.6 11.8 11.7 18.4 12.4 12.7 16.2 23.3 19.3 9.1 15.4 23.4 19.1 16.3 11.1 19.9 28.2 19.3 17.7 16.9 14.0 12.4 13.1 11.7 12.3 15.5 12.8 11.1 17.0 30.0 28.0 8.9 10.2 30.6 31.3 25.1 18.4 13.8 33.1 24.3 16.0 22.3 11.9 15.2 19.9 17.5 13.9 19.7 14.3 10.5 29.3 13.8 10.7 17.4 16.7 20.8 9.9 14.0 16.2 11.8 13.8 9.7 11.0 0.9 1.3 3.4 3.7 1.5 4.8 3.7 2.6 4.6 1.3 5.2 4.5 2.6 0.2 1.8 0.5 2.9 1.9 1.0 13.2 17.7 25.8 26.9 12.4 11.5 12.5 15.6 16.0 12.3 3.0 4.8 19.3 3.8 5.0 8.3 3.7 2.5 1.4 1.2 3.5 5.9 15.7 3.3 7.3 0.9 4.4 8.4 0.0 6.2 18.5 4.6 4.9 1.1 9.4 7.9 3.2 4.1 8.0 0.3 0.6 11.2 2.6 8.5 6.4 8.7 8.4 7.1 10.1 3.5 6.2 5.7 12.9 2.7 16.6 15.5 6.0 13.6 6.7 9.5 3.0 MLH1 "COCA2, FCC2, HNPCC, HNPCC2" ENSG00000076242 "MutL homolog 1" P40692 3 36993332-37050918 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348" "unprognostic (1.26e-2)" "unprognostic (3.88e-3)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (8.24e-5)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (8.63e-3)" "unprognostic (2.10e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (8.86e-2)" 16.3 20.7 18.2 19.4 21.4 24.4 18.7 19.7 19.6 15.3 17.3 28.8 19.6 12.4 18.7 23.6 15.1 16.2 14.4 32.0 17.3 17.7 18.8 20.5 17.8 22.8 19.9 16.0 17.6 18.1 26.0 29.4 17.3 19.2 18.5 17.7 16.7 15.6 18.1 46.4 14.2 14.1 21.1 21.6 20.7 16.5 27.6 21.5 29.0 22.2 19.5 24.5 16.9 21.4 12.0 12.9 13.2 23.2 6.7 13.4 9.0 14.2 22.5 28.1 0.0 12.5 15.7 12.6 21.3 17.0 24.8 26.4 17.0 15.9 35.3 10.6 17.3 14.0 9.8 24.2 18.0 26.6 16.0 12.5 24.7 20.8 23.8 13.9 30.3 17.2 11.7 12.7 23.1 28.8 9.8 15.3 23.9 31.6 16.9 25.1 11.5 31.6 12.4 20.6 14.5 12.4 3.1 34.4 14.9 15.7 15.5 6.0 14.2 21.6 23.0 14.2 16.4 33.2 21.6 12.1 19.5 21.0 19.1 25.0 13.4 36.6 33.1 15.1 28.7 17.5 10.9 11.7 13.2 13.4 19.5 9.7 12.0 8.4 10.7 12.9 10.3 9.6 9.7 3.4 6.7 23.2 6.1 12.5 9.0 18.2 21.4 19.7 19.6 17.3 17.7 19.9 16.0 19.2 21.5 23.8 12.0 16.0 10.7 6.4 19.2 37.1 15.3 16.0 13.6 10.4 9.8 27.1 16.6 12.5 20.3 11.2 5.3 0.0 13.0 23.0 13.4 8.0 7.0 14.5 17.5 3.2 5.2 12.3 14.3 9.5 10.3 11.4 8.5 19.8 7.2 14.3 8.6 7.0 13.1 9.2 17.9 12.9 9.5 37.0 25.4 4.8 16.7 13.1 7.6 3.4 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47402969-47663146 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease mutation, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatogonia: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 7.3 9.8 14.2 12.2 25.5 11.4 14.1 22.6 18.1 9.4 11.6 7.6 5.6 6.5 10.5 13.3 10.8 11.1 4.9 8.4 13.0 14.0 7.3 5.5 7.1 19.7 12.5 17.0 7.9 8.4 15.3 9.1 9.9 18.5 7.9 13.8 12.3 9.4 7.3 6.7 10.3 8.0 7.8 13.8 9.4 6.7 13.4 13.5 37.0 13.9 6.6 21.4 8.5 7.6 7.4 2.9 3.9 4.2 12.2 12.6 6.2 28.3 9.7 26.5 14.3 2.0 5.6 16.1 16.9 8.4 21.0 20.3 18.2 12.3 34.9 22.8 5.9 14.8 12.1 19.8 9.6 31.7 18.0 14.8 25.1 11.2 16.5 2.0 24.5 8.8 3.1 2.8 17.8 4.8 4.7 11.5 0.8 41.8 8.1 16.0 11.3 28.4 18.5 49.9 17.2 11.5 38.1 47.4 20.4 9.1 15.0 22.0 23.9 14.9 11.6 11.9 22.3 11.6 9.6 4.6 13.9 18.3 14.4 18.8 5.2 18.5 48.9 8.5 18.1 8.6 2.8 1.0 3.9 7.9 4.2 8.6 6.3 7.4 9.5 2.3 7.4 12.6 11.9 0.7 12.2 3.2 2.9 10.1 6.2 14.2 25.5 22.6 18.1 13.0 14.0 12.5 17.0 18.5 13.5 8.9 11.5 13.7 5.7 7.3 16.8 13.8 5.1 25.4 13.6 8.7 43.2 14.2 3.3 9.6 13.1 11.7 4.6 23.3 7.3 16.3 8.7 3.4 11.5 1.0 9.6 11.1 3.4 3.7 4.0 17.6 4.9 4.0 8.5 6.4 9.1 20.0 6.0 5.8 6.0 3.5 38.3 0.0 5.5 34.2 59.5 5.6 4.2 8.7 9.8 2.7 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 149.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 2.3;granulocytes: 6.5;T-cells: 8.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 12.9 15.9 22.6 13.3 25.9 5.5 18.5 30.2 26.0 17.6 13.6 19.8 12.2 11.0 16.9 17.0 10.5 15.2 13.1 17.3 21.6 19.6 20.0 15.1 12.7 11.5 19.4 25.6 22.9 16.5 34.1 19.0 19.4 20.9 16.1 14.7 12.1 14.4 20.5 14.8 12.0 12.1 14.5 21.4 11.9 13.0 15.4 21.5 11.6 31.1 7.6 12.4 15.3 19.5 2.3 0.7 6.5 0.4 0.9 8.4 1.0 9.8 12.9 15.7 8.4 13.4 17.5 7.9 8.6 15.5 12.7 14.4 11.6 6.7 9.5 2.5 16.0 15.0 17.3 14.2 12.0 21.5 4.6 8.9 8.4 12.1 5.9 9.5 15.0 7.0 13.8 7.7 13.5 16.5 14.4 6.1 10.1 12.0 9.5 12.1 7.8 12.5 5.5 4.6 6.1 4.3 9.8 24.0 7.6 9.6 14.2 6.5 9.8 15.9 5.3 8.8 11.6 16.2 9.6 8.9 10.2 14.2 12.0 3.2 8.7 4.2 10.5 8.3 6.3 10.5 6.5 0.4 0.9 2.3 0.2 1.6 2.3 4.4 3.9 0.5 2.1 3.3 3.2 1.0 0.9 0.4 0.7 8.4 1.0 22.6 25.9 30.2 23.5 21.6 19.6 19.4 25.6 20.9 21.5 29.8 23.6 12.7 38.9 34.3 61.1 39.2 40.8 29.4 20.5 38.4 129.6 44.8 19.9 23.9 149.0 31.8 28.2 0.0 19.3 22.1 28.2 47.4 10.4 31.7 18.9 66.7 19.0 31.9 24.3 70.0 34.5 21.8 20.3 16.2 26.8 49.7 28.6 35.4 47.4 23.7 66.0 45.3 36.7 28.2 25.6 29.6 41.2 18.5 22.6 60.1 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 61.9;Late spermatids: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 11.8 12.4 23.6 11.1 20.1 10.0 15.4 20.8 28.1 10.8 9.7 9.0 11.8 7.8 10.5 11.3 14.2 11.3 8.0 19.7 26.6 16.4 13.5 11.1 11.9 24.1 18.0 13.5 11.0 12.9 46.8 8.6 6.9 11.4 10.2 8.7 9.5 9.3 15.4 25.7 12.1 8.5 11.9 10.7 10.4 8.8 21.6 10.1 14.9 15.6 11.5 9.9 10.6 10.2 8.5 13.6 6.6 17.3 11.6 15.0 9.8 26.6 10.8 3.8 24.6 7.4 7.4 3.6 21.7 12.2 23.8 20.6 10.6 6.6 7.1 18.0 22.3 16.5 9.5 7.8 12.6 21.3 10.3 6.1 8.4 8.1 7.6 7.9 12.0 10.0 6.8 5.7 16.9 20.6 8.1 16.7 4.6 4.1 6.6 23.1 11.2 7.3 4.8 2.8 6.3 10.2 7.6 20.3 6.8 24.2 12.5 5.8 4.0 12.4 8.4 4.9 4.0 5.4 4.8 31.0 35.5 40.5 15.4 36.6 10.3 8.2 8.5 9.4 4.7 22.6 6.6 9.5 3.6 15.0 13.5 12.8 8.2 11.3 10.1 13.6 8.5 9.8 9.2 2.3 11.6 17.3 9.3 9.4 9.8 23.6 20.1 20.8 28.1 26.6 16.4 18.0 13.5 11.4 10.1 6.0 16.1 9.0 9.6 12.6 16.5 19.9 17.8 6.7 7.9 14.0 9.8 9.9 18.3 42.9 61.9 9.8 8.4 0.0 21.5 6.3 12.6 9.5 23.0 12.5 12.4 28.6 12.6 10.4 10.0 86.8 6.6 7.2 8.5 6.4 7.5 17.3 28.7 15.6 11.7 16.2 8.5 6.5 14.9 21.4 7.2 12.5 3.2 10.9 9.8 8.6 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833275-37034185 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 21.6;lymphoid tissue: 33.4" "Cell type enriched" "Detected in some" 27 "B-cells: 57.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "midbrain: 1.6" "Group enriched" "Detected in some" 209 "memory B-cell: 20.1;naive B-cell: 21.6" "Lineage enriched" "Detected in single" 216 "B-cells: 21.6" "Group enriched" "Detected in some" 8 "Daudi: 21.5;REH: 62.5;U-698: 28.2" "Region enriched" "Detected in single" 11 "midbrain: 4.7" "Group enriched" "Detected in some" 6 "hippocampal formation: 3.8;midbrain: 10.8;pons and medulla: 3.2" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA Nucleoplasm "Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.4 0.2 0.2 33.4 0.2 5.5 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.4 0.2 0.2 0.3 0.5 0.3 0.3 23.2 1.6 0.0 0.2 0.2 0.0 0.5 0.1 0.2 0.3 0.3 0.4 2.5 0.0 0.6 0.2 8.7 0.0 0.3 16.5 0.7 0.9 0.0 2.3 0.4 0.2 30.1 1.3 0.2 21.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.1 0.1 62.5 0.1 0.1 0.0 0.0 4.4 1.0 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 1.6 0.0 0.2 0.0 0.0 0.0 57.6 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 PBRM1 "BAF180, PB1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA015629: AB_1855012, HPA059373: AB_2683994" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" 24.3 14.8 13.8 20.6 15.9 17.2 24.4 19.1 13.8 18.9 18.5 14.0 22.9 12.2 25.9 13.9 19.9 18.9 13.7 15.9 11.1 10.0 11.7 14.5 14.9 16.5 16.5 8.2 25.1 15.4 14.4 30.6 28.0 14.7 16.1 15.3 12.7 17.5 16.2 21.8 17.2 14.3 21.1 15.6 19.1 14.8 13.1 13.7 51.0 22.0 10.5 17.1 22.4 23.0 6.6 10.7 11.1 8.7 4.6 7.4 1.9 12.5 8.1 29.0 14.2 14.3 14.6 20.3 17.3 11.9 20.0 17.6 9.1 8.5 30.4 2.4 20.3 16.6 8.6 25.1 13.1 24.4 32.5 13.5 28.8 15.3 7.0 20.5 24.0 21.9 13.6 15.2 22.4 14.5 15.8 19.3 24.1 16.4 16.7 20.1 4.2 39.5 7.2 17.6 8.5 13.3 20.7 18.2 15.5 8.3 24.5 19.7 21.8 20.8 5.0 16.5 18.4 9.4 13.9 22.2 18.8 14.3 16.2 21.1 12.1 19.0 28.9 11.6 19.5 18.7 10.1 5.0 11.1 4.8 3.2 4.9 3.6 4.8 5.3 4.8 6.6 7.4 4.7 2.7 4.6 8.7 10.7 4.5 1.9 13.8 15.9 19.1 13.8 11.1 10.0 16.5 8.2 14.7 13.7 38.7 54.1 19.5 31.0 35.9 42.0 48.4 28.1 53.5 38.7 22.7 45.2 31.3 16.6 31.4 28.7 40.3 25.3 23.3 40.4 28.9 31.5 35.3 27.8 37.0 45.9 28.6 33.8 35.0 63.3 14.7 31.7 46.6 45.5 50.5 30.6 28.5 42.9 28.1 54.8 13.9 43.3 25.8 45.3 41.9 32.8 45.0 42.6 34.1 34.5 33.3 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 106086320-106109939 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.9" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 49.1;T-cells: 100.2;Urothelial cells: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "eosinophil: 5.6;gdT-cell: 12.6;MAIT T-cell: 19.3;memory CD4 T-cell: 12.0;memory CD8 T-cell: 11.6;naive CD8 T-cell: 6.8;neutrophil: 6.8;T-reg: 15.4" "Group enriched" "Detected in many" 5 "granulocytes: 6.8;T-cells: 19.3" "Cell line enhanced" "Detected in some" "Karpas-707: 68.5;RPMI-8226: 12.8;U-266/70: 25.7;U-266/84: 16.6" "Region enriched" "Detected in single" 6 "olfactory region: 4.4" "Low region specificity" "Detected in all" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 11.6 1.5 1.6 26.3 3.2 10.4 7.0 5.3 1.6 14.0 16.5 1.9 1.4 5.4 11.6 2.2 33.4 3.8 8.1 2.3 1.9 2.0 3.1 2.4 18.8 33.3 2.1 0.5 4.2 1.8 1.2 2.1 9.0 4.9 3.6 11.0 4.3 10.6 3.0 2.0 8.9 18.2 3.4 7.4 24.2 8.6 3.0 1.5 3.1 7.7 35.7 49.9 12.8 18.0 1.5 0.2 6.8 0.6 2.5 19.3 1.3 0.4 0.1 0.3 0.0 0.5 0.7 0.0 2.3 7.2 0.7 1.3 0.4 2.8 0.6 0.1 4.6 0.1 0.1 0.0 1.1 0.8 6.4 0.0 0.1 1.4 0.0 1.1 0.2 0.5 0.7 3.6 1.0 3.0 0.2 0.9 0.3 0.4 68.5 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.0 12.8 0.6 0.1 0.0 0.0 0.3 0.3 0.0 0.5 0.3 0.7 0.4 1.1 0.6 0.6 2.1 25.7 16.6 1.5 1.6 0.4 0.6 1.2 0.4 5.6 12.6 0.6 19.3 1.5 12.0 11.6 0.2 0.5 1.1 6.8 6.8 2.5 0.1 0.2 15.4 1.3 1.6 3.2 5.3 1.6 1.9 2.0 2.1 0.5 4.9 1.5 0.0 9.0 19.7 8.0 17.3 0.8 1.4 0.0 2.7 7.9 3.5 49.1 0.4 0.0 0.3 0.8 20.4 7.3 23.3 0.2 0.5 5.1 3.1 3.5 1.5 19.3 0.0 1.7 8.0 24.7 0.0 0.0 38.5 35.4 47.7 3.1 0.5 4.8 4.3 1.1 0.1 0.4 0.0 16.4 0.3 1.3 36.3 0.6 100.2 2.5 77.0 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863113-87971930 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 29.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Secreted - unknown location" NA NA Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 42.4 24.1 17.7 20.9 17.7 13.5 32.8 39.9 19.7 43.1 26.7 9.9 19.0 15.1 29.8 22.8 26.8 30.3 21.0 19.1 16.0 17.4 19.6 32.4 27.2 30.4 15.7 19.5 29.1 21.3 16.4 23.6 36.4 14.2 35.3 17.7 21.6 16.8 20.8 16.8 20.4 25.4 26.0 11.7 40.9 17.8 18.7 12.5 49.7 25.2 13.3 18.6 29.6 30.9 4.3 5.1 29.6 11.0 4.3 4.7 2.0 10.2 4.8 5.5 5.0 12.8 8.8 5.0 5.5 12.2 6.5 9.1 4.9 12.6 12.1 3.7 9.0 3.8 6.2 7.4 6.3 10.3 6.0 2.1 4.0 12.5 6.0 13.7 13.5 6.9 6.0 17.6 8.2 10.6 27.6 9.1 7.7 3.0 32.9 5.9 7.8 7.6 24.6 2.0 8.9 0.0 11.8 2.9 8.9 10.1 5.8 2.0 9.0 7.3 3.5 9.2 4.6 9.7 19.6 7.9 21.4 5.0 8.3 4.4 10.8 14.0 13.8 6.6 12.8 1.2 8.3 7.9 12.2 3.6 11.0 3.9 4.3 4.0 3.5 5.1 3.7 4.7 4.5 29.6 4.3 7.2 4.2 3.5 2.0 17.7 17.7 39.9 19.7 16.0 17.4 15.7 19.5 14.2 12.5 32.8 55.3 40.2 50.0 49.8 113.3 39.2 40.8 25.4 28.4 27.9 37.3 22.6 28.2 23.2 57.0 44.4 33.9 0.0 25.8 44.5 52.3 36.9 25.3 58.6 31.3 42.9 30.0 47.9 167.4 70.7 52.6 69.1 59.1 27.9 44.1 54.1 30.2 24.6 51.2 30.8 55.8 90.5 118.8 24.9 24.0 52.6 47.9 35.7 39.2 51.2 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303726-48599436 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 19.6 21.5 14.9 23.2 18.4 14.7 28.1 25.6 19.4 18.0 13.2 11.5 19.0 12.3 16.8 19.5 27.9 12.7 15.3 19.5 15.4 15.3 18.1 12.1 25.4 30.1 17.0 11.8 15.2 11.6 12.8 17.2 21.5 16.0 15.5 15.3 11.6 20.0 17.4 27.9 20.3 14.3 16.8 23.6 29.4 13.7 14.4 15.3 39.1 19.9 15.8 25.3 17.4 23.6 20.5 10.3 13.2 12.2 3.6 4.6 4.0 9.1 4.9 13.5 14.5 6.7 7.8 6.1 18.0 15.0 19.0 16.2 4.2 16.2 11.8 4.2 12.0 10.5 12.7 17.5 14.5 29.0 16.5 6.7 21.7 10.2 7.2 7.1 18.6 20.6 4.3 8.9 12.3 15.8 15.9 13.1 29.2 7.2 9.7 21.7 4.3 58.2 9.4 6.6 20.8 5.4 25.0 13.5 13.5 19.7 8.9 0.6 13.8 17.8 8.9 14.7 12.5 9.7 24.3 10.1 11.8 7.7 14.3 16.2 4.3 1.2 0.1 6.2 11.7 15.9 11.0 9.7 5.0 4.6 12.2 3.7 17.4 3.8 4.6 9.3 20.5 3.2 3.8 13.2 3.6 12.1 10.3 4.5 4.0 14.9 18.4 25.6 19.4 15.4 15.3 17.0 11.8 16.0 15.3 3.0 18.7 56.5 18.3 25.2 14.4 15.9 17.8 20.1 14.8 29.6 27.5 5.9 13.3 15.8 20.6 33.6 15.9 0.0 10.4 8.0 15.4 21.4 11.5 14.7 64.6 17.5 16.8 38.6 83.9 10.6 24.2 88.8 25.3 107.4 18.5 21.8 13.3 9.9 26.9 21.1 18.5 19.4 20.6 27.9 14.3 33.4 3.7 20.8 15.0 14.4 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 25.6 17.5 16.0 14.0 16.7 11.4 24.9 29.7 16.0 27.9 22.6 17.9 21.3 15.1 28.2 18.8 21.7 20.5 17.5 19.6 15.3 11.5 21.0 22.0 20.1 16.0 17.2 13.3 30.5 25.0 30.0 28.9 30.6 14.2 27.8 17.4 18.4 23.1 22.8 39.7 18.2 23.4 27.6 13.9 21.7 19.3 17.6 18.4 38.8 35.0 13.9 18.1 29.0 24.1 3.6 3.6 3.4 1.8 2.9 4.7 1.3 8.5 11.4 30.9 8.9 12.8 19.8 17.4 15.1 16.6 20.3 25.5 7.0 2.0 14.3 4.5 13.0 10.4 14.2 17.3 6.8 21.6 12.4 9.8 9.9 11.4 8.0 12.7 17.2 7.8 8.9 11.5 10.0 14.7 19.6 14.7 7.3 11.1 13.2 12.0 4.5 10.2 5.0 16.1 4.6 7.1 13.3 15.7 14.0 9.7 3.7 19.1 11.3 14.1 2.6 9.4 13.7 7.0 10.0 11.0 17.2 8.0 4.3 10.0 19.9 13.8 12.4 11.2 6.7 11.3 0.8 1.8 1.8 3.2 1.1 3.7 2.2 3.3 2.6 3.6 3.6 4.0 4.7 3.4 2.9 1.3 2.9 4.3 1.3 16.0 16.7 29.7 16.0 15.3 11.5 17.2 13.3 14.2 18.4 20.8 23.2 11.8 18.4 22.8 13.2 33.5 40.8 16.0 19.4 21.0 19.6 15.5 10.0 16.2 7.3 23.2 15.6 0.0 10.8 16.8 23.8 31.7 4.6 40.0 13.2 14.3 38.1 23.9 26.1 11.4 30.8 16.7 27.0 5.4 33.8 18.9 18.1 24.3 28.7 18.5 20.8 25.8 29.2 13.9 16.2 23.8 10.5 13.8 26.2 22.5 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838008 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease mutation, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 11.0 15.2 14.6 33.2 15.4 16.9 12.1 30.4 21.9 13.4 25.1 16.4 11.4 41.1 17.2 11.0 15.6 12.3 15.0 12.6 13.2 14.2 14.6 11.7 14.0 32.8 13.0 13.8 21.3 16.1 7.9 15.7 20.8 12.8 11.0 9.4 16.7 40.9 13.1 28.1 14.7 27.4 10.6 12.8 19.8 24.1 37.7 12.9 29.4 15.7 12.0 16.0 21.1 12.2 19.5 9.9 4.8 11.6 7.0 7.5 5.9 1.5 1.0 19.2 1.8 1.8 0.5 3.9 6.1 1.8 1.8 2.9 2.2 1.8 15.7 5.3 0.8 2.0 2.9 4.6 3.0 3.0 2.6 6.7 13.0 1.8 1.3 2.1 13.8 3.8 1.1 2.2 2.1 4.7 0.9 0.9 1.9 3.5 8.7 1.1 3.9 11.2 3.2 5.7 4.7 3.8 7.0 15.5 7.0 1.6 3.0 9.1 6.9 1.4 0.4 10.3 10.4 1.5 2.1 1.6 1.6 6.7 2.6 1.7 9.6 8.8 10.4 1.3 7.6 4.6 4.0 10.0 4.8 3.8 10.2 5.2 19.5 4.6 4.6 9.3 6.4 3.8 2.5 0.8 7.0 11.6 9.9 7.5 5.9 14.6 15.4 30.4 21.9 13.2 14.2 13.0 13.8 12.8 12.9 6.0 10.4 102.1 57.3 44.6 51.7 3.7 38.2 18.7 6.8 45.4 19.6 106.2 71.3 80.0 26.9 31.5 31.9 23.3 67.3 185.0 45.7 53.3 33.5 17.7 66.6 63.5 68.9 36.8 19.7 12.4 33.1 35.4 54.0 63.1 50.5 72.3 62.0 51.8 30.1 65.4 36.9 19.4 58.2 125.7 116.1 46.3 133.9 35.0 61.6 56.7 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 124.0;Late spermatids: 234.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.2 10.3 7.8 14.8 7.4 6.7 16.5 10.4 10.9 9.8 10.4 8.4 14.9 13.9 11.5 10.8 4.4 13.8 7.7 16.0 3.0 26.0 18.8 14.2 0.6 10.5 16.0 14.3 23.9 12.2 11.7 7.5 11.2 8.9 9.8 11.1 26.6 19.2 5.5 15.9 13.7 14.5 15.0 7.3 12.7 21.8 8.4 15.6 8.8 15.6 18.1 13.1 0.0 7.7 11.2 4.7 12.1 23.5 13.2 10.1 11.5 19.8 16.5 37.8 15.9 10.4 10.1 19.1 10.4 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 6.0 13.6 11.1 6.4 14.8 23.6 11.8 17.8 2.7 6.8 22.7 17.7 6.7 6.6 8.1 124.0 14.7 29.5 0.0 11.9 4.5 10.4 14.2 2.3 25.2 12.9 17.5 14.5 16.0 22.2 234.7 22.7 10.4 15.1 17.2 29.2 19.3 13.0 25.9 19.4 8.6 19.8 12.9 20.8 49.9 19.4 13.6 7.3 8.6 33.0 10.9 SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503987-102633535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease mutation, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 126.0;Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA008700: AB_1080125" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.15e-3)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-2)" "unprognostic (3.82e-3)" 10.7 12.8 15.0 15.2 12.8 3.9 18.3 23.0 15.3 13.4 10.4 11.3 12.1 7.7 14.4 13.3 14.7 14.2 16.2 11.0 11.8 7.8 10.8 10.0 21.4 20.5 11.9 11.0 18.0 8.9 20.0 7.8 13.9 10.0 15.4 8.8 11.9 12.6 16.7 14.1 23.1 9.4 14.3 10.7 13.1 7.9 21.1 13.1 19.9 6.2 12.7 15.0 15.2 15.0 2.3 4.5 6.2 5.5 2.8 3.1 2.8 6.3 6.7 10.9 15.7 11.3 9.5 5.3 6.6 12.8 9.6 8.7 6.2 4.7 6.5 18.8 7.3 3.9 4.5 13.4 7.3 6.3 4.0 10.4 15.5 3.9 5.9 5.4 5.6 11.2 10.9 5.8 7.1 5.8 17.6 12.3 6.4 3.4 6.0 5.8 5.3 10.6 8.5 3.1 4.1 5.1 11.5 11.8 3.4 6.3 9.5 3.7 5.9 5.2 4.9 5.9 10.5 10.8 3.7 13.5 4.3 6.1 4.5 7.2 4.9 3.2 4.7 5.3 11.0 2.9 4.2 4.5 6.2 2.5 5.5 2.0 2.3 3.1 2.8 4.5 2.1 2.2 2.5 1.1 2.8 5.5 2.5 1.9 2.8 15.0 12.8 23.0 15.3 11.8 7.8 11.9 11.0 10.0 13.1 0.0 3.0 0.9 2.2 2.7 3.4 3.6 0.0 4.0 4.5 3.5 7.9 6.9 1.7 3.9 126.0 4.3 4.0 0.0 2.6 3.1 5.4 1.9 3.5 4.9 10.4 1.6 1.2 12.9 10.2 78.9 4.6 5.6 0.0 7.2 2.2 2.9 3.5 0.0 6.3 4.4 3.9 0.0 3.4 4.2 4.5 5.6 5.8 5.1 2.8 1.1 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867188-137883312 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.4" "Cell type enhanced" "Detected in many" 10 "Basal keratinocytes: 688.4;Suprabasal keratinocytes: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 31.8;Karpas-707: 48.1;REH: 41.8;U-266/84: 35.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 27.4 6.0 1.5 58.6 1.8 112.4 17.2 0.4 1.5 7.7 15.7 3.2 2.6 5.1 9.7 7.3 12.7 12.1 17.0 11.7 2.1 1.3 6.8 8.1 45.1 38.8 2.1 2.6 37.5 7.2 2.1 3.7 14.5 4.6 13.8 6.3 7.2 8.2 3.5 10.7 20.5 17.2 8.2 3.8 25.9 8.0 9.3 2.1 38.6 5.7 9.2 31.4 23.3 9.5 7.1 18.6 10.0 9.7 7.5 20.5 9.0 8.9 1.4 0.5 0.8 3.0 5.1 2.1 5.1 19.9 1.4 1.8 9.9 2.9 2.0 13.1 5.8 31.8 6.8 0.3 14.7 2.6 14.5 0.5 2.0 5.1 5.8 3.3 2.7 3.6 4.6 2.1 16.8 16.0 1.7 0.8 5.3 4.0 48.1 2.4 0.5 14.7 11.5 0.3 0.6 0.4 41.8 10.4 1.4 4.3 4.3 0.2 0.0 1.0 1.5 4.3 2.1 1.0 3.3 4.0 14.4 1.7 12.9 2.9 15.5 35.9 4.1 5.2 3.4 1.7 5.6 9.7 5.5 14.8 7.1 20.5 6.2 15.1 13.3 10.3 7.1 10.0 7.4 10.0 7.5 3.7 18.6 14.7 9.0 1.5 1.8 0.4 1.5 2.1 1.3 2.1 2.6 4.6 2.1 35.7 83.1 25.1 141.6 688.4 1.0 4.2 30.6 41.5 26.1 0.0 27.5 5.5 1.7 50.3 2.3 27.0 39.0 0.0 23.4 88.6 55.5 117.9 248.4 10.2 45.4 0.0 11.3 45.4 74.2 2.4 6.4 241.1 123.2 82.0 12.5 1.7 27.9 8.2 5.6 2.2 13.3 6.5 87.3 0.9 2.3 651.8 19.3 101.2 8.5 60.3 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 10.4 13.6 15.8 8.8 26.8 13.6 11.4 32.1 28.3 12.7 10.8 22.6 7.9 9.1 14.6 12.3 10.9 12.4 9.7 17.6 13.0 12.1 13.1 9.4 11.6 10.2 12.5 15.1 21.2 12.1 15.9 19.5 15.8 21.1 11.8 12.6 13.1 11.6 10.4 20.0 13.8 11.2 14.2 12.4 13.7 10.6 36.2 14.9 10.5 16.2 8.6 14.2 10.9 11.1 2.8 3.1 4.8 7.0 4.9 7.1 2.6 6.2 7.4 10.1 8.3 10.4 9.9 19.0 8.4 13.6 8.8 8.7 12.5 7.3 14.6 3.7 16.0 13.4 16.2 11.9 8.5 9.0 7.0 6.3 4.6 14.7 10.2 12.4 6.8 6.3 10.7 6.4 11.2 13.8 8.8 10.1 13.0 8.1 8.0 10.0 11.5 6.1 5.8 13.9 9.2 6.2 7.4 19.1 8.2 3.9 8.2 5.1 7.8 9.8 6.1 4.8 12.5 11.1 4.0 10.4 14.4 8.7 8.6 5.7 4.5 10.0 14.2 8.2 4.0 6.4 4.1 4.4 4.8 6.5 7.0 7.1 1.9 3.6 5.7 3.1 2.8 5.9 5.3 1.7 4.9 3.2 1.8 5.7 2.6 15.8 26.8 32.1 28.3 13.0 12.1 12.5 15.1 21.1 14.9 20.8 25.6 10.8 4.8 6.6 26.0 26.6 7.6 21.4 12.5 10.4 35.3 12.8 11.6 9.5 39.6 8.7 6.3 0.0 6.2 19.5 9.1 6.5 8.1 5.0 7.8 23.8 16.1 12.3 8.7 99.6 14.4 7.4 11.8 8.2 7.9 10.4 10.9 8.4 10.6 7.5 25.2 19.4 8.0 18.9 17.8 7.5 17.6 7.1 9.9 6.5 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047465-2089487 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 13.9 11.9 16.9 12.4 20.0 10.9 13.2 35.1 26.9 20.5 17.0 19.4 17.9 14.0 20.1 12.2 13.0 18.6 15.0 14.0 13.3 8.8 11.8 9.8 12.7 10.1 13.8 14.7 21.1 16.1 20.0 18.1 10.6 14.6 13.8 10.8 16.7 22.9 19.6 31.7 14.5 13.2 13.5 11.4 12.9 16.6 21.4 12.9 14.1 20.1 11.3 10.9 18.0 14.0 4.7 5.6 7.7 4.9 3.6 7.0 3.7 7.2 11.6 16.1 18.2 19.2 16.2 13.6 17.4 11.9 13.1 11.2 13.9 13.8 10.9 15.5 14.3 6.1 12.0 9.6 12.6 9.8 8.3 15.8 10.3 22.5 5.7 13.2 12.8 12.5 19.1 8.0 10.6 7.9 15.8 12.3 7.9 10.0 9.8 11.6 14.4 15.2 3.7 16.7 5.4 11.4 24.2 17.6 13.9 5.3 6.5 12.2 23.1 24.8 16.4 8.8 16.7 15.0 9.5 19.4 13.8 9.4 12.3 8.8 21.9 21.8 21.8 5.7 5.2 16.3 6.2 4.9 5.4 7.0 4.7 6.7 4.4 4.4 4.1 5.6 4.7 3.1 4.8 7.7 3.6 3.7 1.5 3.2 3.7 16.9 20.0 35.1 26.9 13.3 8.8 13.8 14.7 14.6 12.9 23.8 17.6 14.9 7.2 8.1 44.2 38.9 20.4 9.4 10.3 19.2 88.4 10.1 3.3 12.8 11.0 19.5 25.8 0.0 12.2 6.5 14.6 9.4 8.1 29.2 9.8 42.9 31.2 34.4 10.5 22.4 26.2 16.6 8.5 7.2 23.8 24.1 15.9 17.5 24.4 6.7 69.1 12.9 11.8 19.4 39.6 8.5 7.8 20.0 24.7 9.2 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141008-10152220 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 54.7" "CAB005430, HPA031631, HPA031632" Uncertain Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB005430: AB_2241850, HPA031631: AB_2673968, HPA031632: AB_2673969" "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 13.8 17.4 18.1 29.2 18.4 24.3 15.4 25.8 21.4 13.3 19.8 19.3 14.5 15.9 15.1 13.6 16.4 14.3 18.9 10.5 17.1 18.5 13.7 16.3 14.6 27.9 13.5 12.3 15.2 22.5 13.8 14.6 18.8 12.8 15.1 16.6 12.5 21.8 13.7 14.8 14.0 22.3 13.4 17.0 22.6 16.2 17.9 11.2 39.2 16.9 11.5 29.3 15.4 19.1 5.4 3.9 8.0 4.1 4.4 4.3 1.7 6.8 6.6 14.6 8.9 13.6 10.5 54.7 6.1 8.7 7.8 9.2 7.8 8.6 24.3 8.3 8.2 11.0 5.9 13.5 8.5 9.6 11.6 12.2 18.9 10.8 10.7 12.9 16.6 15.2 10.6 9.7 10.3 13.0 10.4 8.9 15.3 16.8 18.5 7.6 12.4 15.8 12.2 9.8 7.4 8.5 20.1 12.9 12.2 9.5 17.8 5.5 18.3 12.8 6.8 7.3 9.2 13.4 21.1 7.7 7.7 10.4 7.2 9.5 13.2 26.9 38.8 8.6 20.0 7.0 2.6 4.1 3.3 3.8 2.5 3.6 4.1 2.9 4.3 3.9 5.4 2.5 2.7 8.0 4.4 3.2 2.4 3.1 1.7 18.1 18.4 25.8 21.4 17.1 18.5 13.5 12.3 12.8 11.2 11.9 12.2 25.5 15.5 13.1 15.6 5.0 20.4 5.3 5.7 15.7 17.7 13.9 6.6 9.9 7.6 12.1 10.5 0.0 4.5 15.8 9.5 19.0 4.7 12.3 12.9 17.5 13.8 17.2 20.2 6.1 13.0 18.5 11.8 15.4 9.3 10.4 8.5 9.3 10.6 7.3 13.9 6.5 6.2 14.4 25.6 17.9 14.4 17.5 10.7 19.5 WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "Wilms tumor 1" P19544 11 32387775-32435630 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 69.0;fallopian tube: 34.5;ovary: 53.4" "Cell type enhanced" "Detected in some" 18 "Collecting duct cells: 19.2;Late spermatids: 5.9;Leydig cells: 7.8;Sertoli cells: 6.5" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.5;HMC-1: 17.4;K-562: 12.2;NB-4: 32.6;THP-1: 15.6" "Region enhanced" "Detected in single" "pons and medulla: 0.5" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" 10.3 0.0 0.2 1.8 0.6 0.0 0.2 0.2 0.5 20.3 1.5 0.2 3.7 0.0 69.0 9.3 0.4 34.5 0.8 2.1 0.9 0.0 5.3 0.2 0.8 0.5 0.2 0.2 53.4 0.2 0.0 0.2 6.9 0.3 0.9 0.0 0.2 0.2 4.2 0.2 0.0 0.4 23.7 0.2 14.6 0.0 24.5 0.2 0.2 0.3 0.2 0.2 1.3 4.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 4.7 13.5 0.0 1.2 3.8 9.0 17.4 0.0 0.0 2.8 0.0 0.0 0.0 2.8 12.2 0.1 2.7 0.0 7.9 32.6 0.7 0.0 3.8 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 1.8 15.6 0.1 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 0.2 0.5 0.9 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 19.2 0.0 0.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 5.9 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 0.0 6.5 0.0 1.9 0.9 0.0 0.7 0.0 0.0 0.1