Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"MS evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific NX"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific NX"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific NX"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific NX"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific NX"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific NX"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific pTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific pTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [NX]"	"Tissue RNA - adrenal gland [NX]"	"Tissue RNA - amygdala [NX]"	"Tissue RNA - appendix [NX]"	"Tissue RNA - basal ganglia [NX]"	"Tissue RNA - bone marrow [NX]"	"Tissue RNA - breast [NX]"	"Tissue RNA - cerebellum [NX]"	"Tissue RNA - cerebral cortex [NX]"	"Tissue RNA - cervix, uterine [NX]"	"Tissue RNA - colon [NX]"	"Tissue RNA - corpus callosum [NX]"	"Tissue RNA - ductus deferens [NX]"	"Tissue RNA - duodenum [NX]"	"Tissue RNA - endometrium 1 [NX]"	"Tissue RNA - epididymis [NX]"	"Tissue RNA - esophagus [NX]"	"Tissue RNA - fallopian tube [NX]"	"Tissue RNA - gallbladder [NX]"	"Tissue RNA - heart muscle [NX]"	"Tissue RNA - hippocampal formation [NX]"	"Tissue RNA - hypothalamus [NX]"	"Tissue RNA - kidney [NX]"	"Tissue RNA - liver [NX]"	"Tissue RNA - lung [NX]"	"Tissue RNA - lymph node [NX]"	"Tissue RNA - midbrain [NX]"	"Tissue RNA - olfactory region [NX]"	"Tissue RNA - ovary [NX]"	"Tissue RNA - pancreas [NX]"	"Tissue RNA - parathyroid gland [NX]"	"Tissue RNA - pituitary gland [NX]"	"Tissue RNA - placenta [NX]"	"Tissue RNA - pons and medulla [NX]"	"Tissue RNA - prostate [NX]"	"Tissue RNA - rectum [NX]"	"Tissue RNA - retina [NX]"	"Tissue RNA - salivary gland [NX]"	"Tissue RNA - seminal vesicle [NX]"	"Tissue RNA - skeletal muscle [NX]"	"Tissue RNA - skin 1 [NX]"	"Tissue RNA - small intestine [NX]"	"Tissue RNA - smooth muscle [NX]"	"Tissue RNA - spinal cord [NX]"	"Tissue RNA - spleen [NX]"	"Tissue RNA - stomach 1 [NX]"	"Tissue RNA - testis [NX]"	"Tissue RNA - thalamus [NX]"	"Tissue RNA - thymus [NX]"	"Tissue RNA - thyroid gland [NX]"	"Tissue RNA - tongue [NX]"	"Tissue RNA - tonsil [NX]"	"Tissue RNA - urinary bladder [NX]"	"Tissue RNA - vagina [NX]"	"Tissue RNA - B-cells [NX]"	"Tissue RNA - dendritic cells [NX]"	"Tissue RNA - granulocytes [NX]"	"Tissue RNA - monocytes [NX]"	"Tissue RNA - NK-cells [NX]"	"Tissue RNA - T-cells [NX]"	"Tissue RNA - total PBMC [NX]"	"Cell RNA - A-431 [NX]"	"Cell RNA - A549 [NX]"	"Cell RNA - AF22 [NX]"	"Cell RNA - AN3-CA [NX]"	"Cell RNA - ASC diff [NX]"	"Cell RNA - ASC TERT1 [NX]"	"Cell RNA - BEWO [NX]"	"Cell RNA - BJ [NX]"	"Cell RNA - BJ hTERT+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [NX]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]"	"Cell RNA - CACO-2 [NX]"	"Cell RNA - CAPAN-2 [NX]"	"Cell RNA - Daudi [NX]"	"Cell RNA - EFO-21 [NX]"	"Cell RNA - fHDF/TERT166 [NX]"	"Cell RNA - GAMG [NX]"	"Cell RNA - HaCaT [NX]"	"Cell RNA - HAP1 [NX]"	"Cell RNA - HBEC3-KT [NX]"	"Cell RNA - HBF TERT88 [NX]"	"Cell RNA - HDLM-2 [NX]"	"Cell RNA - HEK 293 [NX]"	"Cell RNA - HEL [NX]"	"Cell RNA - HeLa [NX]"	"Cell RNA - Hep G2 [NX]"	"Cell RNA - HHSteC [NX]"	"Cell RNA - HL-60 [NX]"	"Cell RNA - HMC-1 [NX]"	"Cell RNA - HSkMC [NX]"	"Cell RNA - hTCEpi [NX]"	"Cell RNA - hTEC/SVTERT24-B [NX]"	"Cell RNA - hTERT-HME1 [NX]"	"Cell RNA - hTERT-RPE1 [NX]"	"Cell RNA - HUVEC TERT2 [NX]"	"Cell RNA - JURKAT [NX]"	"Cell RNA - K-562 [NX]"	"Cell RNA - Karpas-707 [NX]"	"Cell RNA - LHCN-M2 [NX]"	"Cell RNA - MCF7 [NX]"	"Cell RNA - MOLT-4 [NX]"	"Cell RNA - NB-4 [NX]"	"Cell RNA - NTERA-2 [NX]"	"Cell RNA - OE19 [NX]"	"Cell RNA - PC-3 [NX]"	"Cell RNA - REH [NX]"	"Cell RNA - RH-30 [NX]"	"Cell RNA - RPMI-8226 [NX]"	"Cell RNA - RPTEC TERT1 [NX]"	"Cell RNA - RT4 [NX]"	"Cell RNA - SCLC-21H [NX]"	"Cell RNA - SH-SY5Y [NX]"	"Cell RNA - SiHa [NX]"	"Cell RNA - SK-BR-3 [NX]"	"Cell RNA - SK-MEL-30 [NX]"	"Cell RNA - SuSa [NX]"	"Cell RNA - T-47d [NX]"	"Cell RNA - THP-1 [NX]"	"Cell RNA - TIME [NX]"	"Cell RNA - U-138 MG [NX]"	"Cell RNA - U-2 OS [NX]"	"Cell RNA - U-2197 [NX]"	"Cell RNA - U-251 MG [NX]"	"Cell RNA - U-266/70 [NX]"	"Cell RNA - U-266/84 [NX]"	"Cell RNA - U-698 [NX]"	"Cell RNA - U-87 MG [NX]"	"Cell RNA - U-937 [NX]"	"Cell RNA - WM-115 [NX]"	"Blood RNA - basophil [NX]"	"Blood RNA - classical monocyte [NX]"	"Blood RNA - eosinophil [NX]"	"Blood RNA - gdT-cell [NX]"	"Blood RNA - intermediate monocyte [NX]"	"Blood RNA - MAIT T-cell [NX]"	"Blood RNA - memory B-cell [NX]"	"Blood RNA - memory CD4 T-cell [NX]"	"Blood RNA - memory CD8 T-cell [NX]"	"Blood RNA - myeloid DC [NX]"	"Blood RNA - naive B-cell [NX]"	"Blood RNA - naive CD4 T-cell [NX]"	"Blood RNA - naive CD8 T-cell [NX]"	"Blood RNA - neutrophil [NX]"	"Blood RNA - NK-cell [NX]"	"Blood RNA - non-classical monocyte [NX]"	"Blood RNA - plasmacytoid DC [NX]"	"Blood RNA - T-reg [NX]"	"Blood RNA - total PBMC [NX]"	"Brain RNA - amygdala [NX]"	"Brain RNA - basal ganglia [NX]"	"Brain RNA - cerebellum [NX]"	"Brain RNA - cerebral cortex [NX]"	"Brain RNA - hippocampal formation [NX]"	"Brain RNA - hypothalamus [NX]"	"Brain RNA - midbrain [NX]"	"Brain RNA - olfactory region [NX]"	"Brain RNA - pons and medulla [NX]"	"Brain RNA - thalamus [NX]"	"Single Cell Type RNA - Alveolar cells type 1 [NX]"	"Single Cell Type RNA - Alveolar cells type 2 [NX]"	"Single Cell Type RNA - B-cells [NX]"	"Single Cell Type RNA - Basal glandular cells [NX]"	"Single Cell Type RNA - Basal keratinocytes [NX]"	"Single Cell Type RNA - Bipolar cells [NX]"	"Single Cell Type RNA - Cardiomyocytes [NX]"	"Single Cell Type RNA - Cholangiocytes [NX]"	"Single Cell Type RNA - Ciliated cells [NX]"	"Single Cell Type RNA - Club cells [NX]"	"Single Cell Type RNA - Collecting duct cells [NX]"	"Single Cell Type RNA - Cone photoreceptor cells [NX]"	"Single Cell Type RNA - Cytotrophoblasts [NX]"	"Single Cell Type RNA - Distal tubular cells [NX]"	"Single Cell Type RNA - Ductal cells [NX]"	"Single Cell Type RNA - Early spermatids [NX]"	"Single Cell Type RNA - Endothelial cells [NX]"	"Single Cell Type RNA - Enterocytes [NX]"	"Single Cell Type RNA - Erythroid cells [NX]"	"Single Cell Type RNA - Exocrine glandular cells [NX]"	"Single Cell Type RNA - Extravillous trophoblasts [NX]"	"Single Cell Type RNA - Fibroblasts [NX]"	"Single Cell Type RNA - Glandular cells [NX]"	"Single Cell Type RNA - granulocytes [NX]"	"Single Cell Type RNA - Hepatocytes [NX]"	"Single Cell Type RNA - Hofbauer cells [NX]"	"Single Cell Type RNA - Horizontal cells [NX]"	"Single Cell Type RNA - Intestinal endocrine cells [NX]"	"Single Cell Type RNA - Ito cells [NX]"	"Single Cell Type RNA - Kupffer cells [NX]"	"Single Cell Type RNA - Late spermatids [NX]"	"Single Cell Type RNA - Leydig cells [NX]"	"Single Cell Type RNA - Macrophages [NX]"	"Single Cell Type RNA - Melanocytes [NX]"	"Single Cell Type RNA - monocytes [NX]"	"Single Cell Type RNA - Mucus-secreting cells [NX]"	"Single Cell Type RNA - Muller glia cells [NX]"	"Single Cell Type RNA - Pancreatic endocrine cells [NX]"	"Single Cell Type RNA - Paneth cells [NX]"	"Single Cell Type RNA - Peritubular cells [NX]"	"Single Cell Type RNA - Proximal tubular cells [NX]"	"Single Cell Type RNA - Rod photoreceptor cells [NX]"	"Single Cell Type RNA - Sertoli cells [NX]"	"Single Cell Type RNA - Smooth muscle cells [NX]"	"Single Cell Type RNA - Spermatocytes [NX]"	"Single Cell Type RNA - Spermatogonia [NX]"	"Single Cell Type RNA - Suprabasal keratinocytes [NX]"	"Single Cell Type RNA - Syncytiotrophoblasts [NX]"	"Single Cell Type RNA - T-cells [NX]"	"Single Cell Type RNA - Undifferentiated cells [NX]"	"Single Cell Type RNA - Urothelial cells [NX]"
ALB		ENSG00000163631	Albumin	P02768	4	73397114-73421412	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"			"Cancer-related genes, Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	81	"liver: 3075.8"	"Cell type enriched"	"Detected in many"	4	"Hepatocytes: 49859.9"	"Cancer enriched"	"Detected in many"	384	"liver cancer: 14213.7"	"Not detected"	"Not detected"			"Cell type enriched"	"Detected in single"	13	"naive CD4 T-cell: 1.3"	"Lineage enriched"	"Detected in single"	13	"T-cells: 1.3"	"Cell line enriched"	"Detected in some"	39	"Hep G2: 315.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB006262, HPA031024, HPA031025"	Enhanced		Enhanced	"Endoplasmic reticulum,Golgi apparatus"	"Secreted to blood"	NA	NA	40000000000000		"Golgi apparatus"	"Endoplasmic reticulum"	"CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704"	"unprognostic (1.38e-1)"	"unprognostic (8.72e-2)"	"unprognostic (1.73e-1)"	"unprognostic (2.60e-1)"	"unprognostic (4.44e-1)"	"unprognostic (2.46e-1)"	"unprognostic (9.53e-3)"	"unprognostic (2.16e-2)"	"unprognostic (2.40e-1)"	"unprognostic (6.43e-2)"	"unprognostic (3.84e-2)"	"unprognostic (5.37e-2)"	"unprognostic (1.25e-1)"	"prognostic unfavorable (7.87e-4)"	"unprognostic (7.23e-2)"	"unprognostic (1.05e-3)"	"unprognostic (1.02e-2)"	0.1	0.0	0.1	0.2	0.1	0.0	0.1	0.1	0.3	0.1	0.1	0.1	0.1	0.0	0.1	0.8	0.1	0.0	0.1	0.1	0.1	0.0	4.9	3075.8	0.1	0.1	0.1	0.1	0.1	38.0	0.0	0.1	0.1	0.2	0.1	0.0	0.1	0.1	0.1	0.1	0.0	0.1	0.1	0.1	1.0	0.0	0.3	0.1	0.1	0.3	0.1	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	2.2	0.1	315.9	0.0	8.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.1	7.0	0.0	0.0	0.2	0.0	0.0	3.7	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.1	0.0	0.0	0.5	0.0	2.6	0.0	2.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.3	0.1	0.0	0.1	0.1	0.2	0.1	0.0	0.0	683.8	0.0	0.0	0.0	0.1	12066.1	0.0	0.0	36.6	0.0	0.8	61.3	4.3	2.0	0.0	0.0	1612.0	237.4	2.3	0.2	0.1	0.0	49859.9	8.2	0.0	1.7	1417.3	1529.6	0.0	0.0	0.0	0.0	1.8	0.0	0.0	261.7	0.0	0.0	442.7	0.0	0.0	0.4	0.2	0.2	0.1	17.7	22.3	0.0	0.0
CTSA	"GSL, PPGB"	ENSG00000064601	"Cathepsin A"	P10619	20	45890144-45898820	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"		"Carboxypeptidase, Hydrolase, Protease"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 125.7"	"Cell type enhanced"	"Detected in many"	4	"Hofbauer cells: 279.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 113.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB024930, HPA031068, HPA072487"	Enhanced		Enhanced	Vesicles	"Intracellular and membrane"	NA	NA		18000000	Vesicles		"CAB024930: , HPA031068: AB_10601205, HPA072487: "	"unprognostic (8.61e-2)"	"unprognostic (3.37e-1)"	"unprognostic (4.30e-2)"	"unprognostic (2.13e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.21e-1)"	"prognostic unfavorable (1.95e-4)"	"unprognostic (6.33e-2)"	"unprognostic (9.53e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.83e-1)"	"unprognostic (6.85e-2)"	"unprognostic (7.57e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.05e-2)"	"unprognostic (1.71e-1)"	"unprognostic (8.40e-2)"	29.0	125.7	12.0	22.8	19.5	22.1	35.3	11.4	30.0	14.1	50.6	17.4	16.2	29.4	18.2	19.3	20.7	12.7	28.0	32.6	11.5	11.6	88.2	43.8	28.4	38.9	12.3	16.1	23.9	19.2	28.3	16.5	47.7	15.7	18.2	50.5	30.1	20.5	15.1	19.3	28.2	40.6	19.6	11.9	38.8	19.7	14.3	11.2	8.0	18.1	24.9	22.4	23.3	18.7	7.0	16.6	81.1	46.1	12.0	31.2	50.0	14.1	14.5	2.7	12.4	113.6	58.9	6.3	20.3	54.2	22.3	29.1	27.3	38.1	3.0	23.6	38.1	84.2	22.6	7.3	13.7	14.0	5.9	6.8	8.0	10.2	47.5	25.3	12.7	33.2	46.7	16.5	14.4	3.2	55.8	24.2	3.9	7.9	46.7	24.1	29.1	3.2	11.8	2.8	21.6	34.6	5.1	14.1	16.8	17.8	12.5	5.5	5.2	33.9	59.3	56.7	7.3	14.5	18.3	22.3	44.8	10.5	25.3	15.9	23.1	29.1	2.1	80.6	16.9	18.4	60.6	46.1	81.1	7.5	26.6	31.2	7.0	12.9	13.2	16.6	3.6	4.7	6.9	24.7	12.0	17.7	6.6	23.9	50.0	12.0	19.5	11.4	30.0	11.5	11.6	12.3	16.1	15.7	11.2	32.8	24.6	40.4	31.0	21.5	54.2	10.9	58.6	22.7	26.1	68.0	56.9	86.8	33.2	172.8	2.3	41.6	257.8	0.0	146.8	91.1	44.1	21.0	9.2	53.3	279.4	44.5	51.9	105.0	166.6	3.6	30.5	81.3	106.3	136.1	70.2	92.8	127.7	92.2	25.8	168.1	30.9	25.8	46.4	6.2	32.4	19.9	120.5	54.2	85.6	31.9
CTSB		ENSG00000164733	"Cathepsin B"	P07858	8	11842524-11869448	"Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins"		"Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"thyroid gland: 297.0"	"Cell type enhanced"	"Detected in all"	11	"Hofbauer cells: 2617.6;Kupffer cells: 1392.4"	"Cancer enhanced"	"Detected in all"		"thyroid cancer: 1446.9"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"basophil: 53.1;classical monocyte: 127.4;intermediate monocyte: 97.0;myeloid DC: 68.0;non-classical monocyte: 54.7;plasmacytoid DC: 95.4"	"Group enriched"	"Detected in all"	5	"dendritic cells: 95.4;granulocytes: 53.1;monocytes: 127.4"	"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 239.8;fHDF/TERT166: 139.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000457, HPA018156, HPA048998"	Enhanced		Supported	Nucleoli,Vesicles	"Secreted to blood"	NA	NA		130000000	Vesicles	Nucleoli	"CAB000457: , HPA018156: AB_1846069, HPA048998: "	"unprognostic (5.74e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.38e-2)"	"unprognostic (2.17e-2)"	"unprognostic (2.98e-3)"	"unprognostic (5.96e-2)"	"unprognostic (1.36e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.82e-2)"	"unprognostic (1.06e-1)"	"unprognostic (7.61e-2)"	"unprognostic (8.30e-2)"	"unprognostic (2.85e-1)"	"unprognostic (7.39e-2)"	"unprognostic (4.12e-2)"	"prognostic favorable (5.76e-4)"	"prognostic unfavorable (9.02e-4)"	227.9	42.1	19.6	67.2	24.4	14.7	67.6	14.9	31.4	76.7	49.1	30.1	22.7	29.9	53.2	44.8	54.2	52.4	43.6	120.7	18.3	23.7	95.6	167.8	94.3	175.1	29.1	16.5	44.2	31.6	13.8	21.6	68.7	24.8	42.6	27.9	33.8	63.7	33.6	41.3	22.8	51.2	51.1	35.9	116.4	26.7	21.5	20.4	18.1	297.0	25.9	38.4	56.8	62.2	7.9	95.4	53.1	127.4	5.3	17.1	108.5	6.4	29.5	3.8	16.2	66.6	74.9	11.8	122.8	239.8	43.0	51.0	14.0	38.4	0.1	17.8	139.3	57.7	35.8	5.2	33.9	27.2	3.2	5.0	9.5	3.4	34.5	67.8	2.1	7.1	82.1	46.2	38.9	34.8	74.9	84.1	2.8	7.9	21.7	35.7	5.2	0.8	3.5	3.2	75.8	9.9	3.4	3.8	16.6	13.1	10.2	1.6	9.6	14.2	7.7	64.0	11.7	12.5	6.4	116.4	73.1	24.8	23.4	22.8	21.6	15.7	0.6	83.9	8.2	34.2	53.1	127.4	16.3	5.2	97.0	7.2	7.9	17.1	5.8	68.0	6.1	9.6	4.1	18.5	5.3	54.7	95.4	13.4	108.5	19.6	24.4	14.9	28.0	18.3	23.7	29.1	16.5	24.8	20.4	101.3	205.9	73.7	364.9	48.5	44.4	251.7	175.8	137.9	227.5	108.2	39.3	224.9	23.2	276.8	13.3	119.6	152.5	210.2	211.7	280.5	149.9	239.1	169.3	203.7	2617.6	55.6	148.7	214.9	1392.4	12.2	70.8	859.7	153.5	399.5	80.9	115.8	264.9	108.7	87.4	331.7	35.7	38.8	121.0	4.8	18.5	35.4	543.3	50.7	114.7	284.4
CTSC	"DPP1, PALS, PLS"	ENSG00000109861	"Cathepsin C"	P53634	11	88293592-88337787	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"	"Disease mutation, Palmoplantar keratoderma"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 218.6"	"Cell type enhanced"	"Detected in many"	11	"Cytotrophoblasts: 362.7;Hofbauer cells: 897.2;Macrophages: 364.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BJ hTERT+: 111.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB025364, HPA066610, HPA068434"	Enhanced		Supported	Vesicles	"Intracellular and membrane"	No	No		19000000	Vesicles		"CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989"	"unprognostic (4.05e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.10e-1)"	"unprognostic (3.70e-2)"	"unprognostic (1.45e-2)"	"prognostic unfavorable (9.30e-5)"	"unprognostic (1.62e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.56e-2)"	"unprognostic (3.11e-2)"	"unprognostic (3.35e-1)"	"prognostic favorable (4.80e-4)"	"unprognostic (2.93e-1)"	"unprognostic (4.35e-2)"	"unprognostic (8.10e-2)"	"unprognostic (4.07e-2)"	40.7	20.5	6.7	44.5	10.6	12.0	35.3	1.5	5.6	14.0	25.3	7.1	6.2	20.4	16.1	24.0	21.8	16.7	36.6	53.3	6.8	6.5	62.7	18.1	110.1	218.6	12.5	3.6	11.0	24.8	3.8	17.3	43.4	9.4	13.8	33.1	27.0	35.1	5.8	10.0	11.7	28.5	14.2	14.6	86.6	13.5	10.8	9.2	19.5	17.7	25.3	30.0	30.2	16.9	8.5	75.9	52.5	92.6	34.7	42.4	31.2	11.1	11.5	4.5	9.4	12.1	32.9	30.1	76.8	111.7	43.9	31.7	31.1	51.7	17.4	40.9	41.7	10.1	18.1	7.0	32.5	35.0	30.7	12.7	22.7	31.8	35.0	16.2	28.9	15.4	45.8	23.0	33.8	69.4	37.0	43.1	16.9	20.6	21.1	5.3	2.1	13.0	39.9	23.5	75.5	35.6	17.0	4.7	30.9	56.4	18.8	1.2	9.4	12.9	17.1	10.0	27.9	3.8	19.8	20.9	3.0	27.2	20.9	48.8	8.9	12.8	17.7	7.9	60.9	16.6	12.5	32.5	52.5	42.4	69.3	36.5	8.5	19.5	37.8	35.1	4.6	9.9	23.8	37.2	34.7	92.6	75.9	28.4	31.2	6.7	10.6	1.5	5.6	6.8	6.5	12.5	3.6	9.4	9.2	20.8	83.9	64.9	5.0	26.8	1.0	2.5	56.0	80.3	93.3	38.4	0.0	362.7	24.9	14.0	1.2	41.8	29.0	0.0	79.6	130.7	85.3	3.1	72.8	14.0	897.2	0.0	10.9	24.5	290.2	4.0	183.8	364.2	45.5	139.7	15.7	0.6	35.1	69.1	24.1	150.6	0.6	58.2	183.3	3.0	11.5	23.7	190.1	167.5	36.3	14.2
CTSD	"CLN10, CPSD"	ENSG00000117984	"Cathepsin D"	P07339	11	1752752-1764573	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"		"Aspartyl protease, Hydrolase, Protease"	"Alzheimer disease, Cancer-related genes, Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"	11	"Enterocytes: 1407.0;Hofbauer cells: 3678.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"CAPAN-2: 190.9;hTERT-RPE1: 255.7;SK-BR-3: 182.5"									"CAB000109, HPA003001"	Supported				"Secreted to blood"	NA	NA		540000000			"CAB000109: , HPA003001: AB_1078404"	"unprognostic (9.95e-2)"	"unprognostic (1.62e-1)"	"prognostic unfavorable (2.46e-4)"	"unprognostic (1.09e-1)"	"unprognostic (1.71e-3)"	"unprognostic (2.65e-2)"	"unprognostic (9.40e-3)"	"unprognostic (1.11e-1)"	"unprognostic (1.52e-1)"	"unprognostic (1.12e-3)"	"unprognostic (1.59e-1)"	"unprognostic (1.86e-2)"	"prognostic favorable (4.93e-5)"	"unprognostic (8.98e-2)"	"unprognostic (3.39e-2)"	"unprognostic (2.13e-2)"	"unprognostic (1.60e-1)"	151.9	148.7	21.4	32.8	27.0	83.7	67.7	18.6	47.4	56.3	59.3	41.4	41.9	61.6	25.9	48.2	46.2	34.2	90.0	86.0	25.3	27.6	150.5	163.5	102.6	81.1	49.6	25.7	41.2	62.3	21.3	24.9	56.1	42.8	33.9	33.7	234.4	64.1	42.3	76.2	50.8	90.9	23.3	36.7	87.6	47.0	29.8	29.7	21.1	36.3	42.9	41.4	64.6	43.5	4.9	22.7	51.1	83.8	28.4	26.1	58.7	13.8	37.5	4.3	18.0	54.9	18.8	7.0	10.3	32.0	13.8	16.4	9.3	190.9	3.3	26.6	26.5	103.7	74.7	6.2	11.5	3.8	14.3	13.6	5.1	7.1	11.6	58.0	11.8	54.6	30.2	50.5	7.4	13.7	255.7	10.1	4.4	6.1	20.6	24.4	51.1	3.0	6.6	10.2	56.8	15.1	4.3	5.3	12.5	48.7	43.4	6.0	5.9	12.2	182.5	34.6	6.5	71.4	16.3	12.7	42.1	6.4	5.8	16.4	28.3	35.5	2.1	61.3	31.9	35.2	29.0	83.8	25.2	26.1	47.6	15.1	4.9	12.2	18.3	22.7	3.2	14.3	18.3	51.1	28.4	38.5	19.2	13.5	58.7	21.4	27.0	18.6	47.4	25.3	27.6	49.6	25.7	42.8	29.7	104.2	261.1	102.1	219.0	64.0	155.9	226.4	366.9	115.1	126.3	519.9	104.1	198.5	92.9	592.1	2.7	92.6	1407.0	70.0	321.5	138.5	112.5	108.8	466.1	497.1	3678.7	249.5	153.3	833.5	1087.5	9.0	100.4	573.5	215.9	205.6	341.0	186.6	426.0	610.2	120.6	259.1	69.6	109.9	103.0	22.4	56.8	71.8	394.2	188.4	260.3	345.7
CTSE		ENSG00000196188	"Cathepsin E"	P14091	1	206009264-206023909	"Enzymes, Predicted intracellular proteins"		"Aspartyl protease, Hydrolase, Protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"gallbladder: 57.9;intestine: 47.3;stomach 1: 153.0"	"Cell type enhanced"	"Detected in some"	14	"Alveolar cells type 1: 98.3;Club cells: 77.3;Exocrine glandular cells: 240.3;Pancreatic endocrine cells: 151.8;Paneth cells: 175.6"	"Group enriched"	"Detected in many"	8	"lung cancer: 68.8;pancreatic cancer: 297.4;stomach cancer: 200.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	44	"OE19: 201.7"	"Not detected"	"Not detected"							"HPA012940, CAB032687"	Enhanced				"Intracellular and membrane"	NA	NA					"CAB032687: AB_637901, HPA012940: AB_2668773"	"unprognostic (1.17e-2)"	"unprognostic (2.45e-1)"	"unprognostic (1.31e-2)"	"unprognostic (2.72e-2)"		"unprognostic (1.35e-2)"	"unprognostic (2.52e-3)"	"unprognostic (1.45e-1)"	"unprognostic (3.29e-2)"	"unprognostic (2.87e-2)"	"unprognostic (1.20e-2)"	"unprognostic (1.39e-1)"	"unprognostic (6.37e-3)"	"unprognostic (1.42e-1)"	"unprognostic (5.45e-2)"	"unprognostic (2.61e-2)"	"prognostic favorable (5.26e-5)"	0.2	0.1	0.1	3.7	0.1	3.0	0.1	0.1	0.1	0.1	47.3	0.3	0.8	29.3	0.1	0.7	0.6	0.5	57.9	0.3	0.1	0.1	0.2	0.2	24.9	0.0	0.1	0.0	0.1	2.2	0.0	0.5	0.0	0.1	1.3	3.2	0.0	0.1	0.0	0.1	0.1	29.7	0.0	0.1	0.2	153.0	0.1	0.0	0.3	4.2	0.0	1.1	1.8	0.4	0.2	0.7	0.0	0.4	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	201.7	0.0	0.0	0.0	0.0	0.0	4.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.2	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.4	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.0	98.3	20.9	0.0	0.1	0.0	0.0	0.4	17.8	13.4	77.3	0.0	0.0	0.0	0.0	44.2	0.0	0.0	5.1	23.3	240.3	0.0	0.0	0.1	0.0	0.0	0.2	0.0	2.4	0.0	0.3	0.0	0.0	0.0	0.0	2.8	8.1	0.0	151.8	175.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.9	0.2
CTSF	"CATSF, CLN13"	ENSG00000174080	"Cathepsin F"	Q9UBX1	11	66563463-66568841	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"	"Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"	6	"Late spermatids: 256.1;Muller glia cells: 186.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"NK-cells: 7.5;T-cells: 9.7"	"Cell line enhanced"	"Detected in many"		"HSkMC: 28.4;SK-MEL-30: 52.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002141, HPA031431"	Approved		Uncertain	"Vesicles,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA		3600000	Cytosol	"Vesicles, Plasma membrane"	"CAB002141: AB_563471, HPA031431: "	"unprognostic (1.52e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.03e-1)"	"unprognostic (7.22e-3)"	"unprognostic (2.25e-2)"	"unprognostic (6.72e-2)"	"unprognostic (2.67e-2)"	"unprognostic (2.76e-2)"	"unprognostic (3.69e-1)"	"unprognostic (4.14e-1)"	"unprognostic (1.69e-2)"	"unprognostic (9.12e-2)"	"prognostic favorable (8.92e-7)"	"unprognostic (1.36e-2)"	"unprognostic (1.28e-1)"	"unprognostic (3.89e-1)"	"unprognostic (2.42e-1)"	28.1	29.4	24.7	8.0	29.0	1.8	31.1	38.4	47.1	37.3	23.8	32.6	25.2	5.8	38.1	29.8	12.9	34.3	37.3	34.5	25.3	20.5	29.8	45.4	17.3	8.5	28.0	26.0	68.2	23.1	42.6	15.9	20.2	25.4	32.3	8.1	35.0	35.5	37.8	35.8	19.7	9.4	34.6	22.4	10.4	17.8	37.1	30.1	0.8	18.6	14.2	6.3	22.2	21.5	2.1	1.1	0.5	0.7	7.5	9.7	2.4	0.1	9.3	5.0	13.0	21.5	8.7	3.6	6.6	16.7	6.8	4.8	0.0	8.3	0.0	11.1	14.4	0.3	0.9	8.6	2.8	3.6	2.2	0.0	0.3	3.8	0.0	12.0	0.1	5.1	28.4	9.7	1.5	1.1	20.3	4.3	2.7	2.9	1.5	8.5	1.9	0.1	1.1	0.6	5.0	3.4	0.0	1.9	1.6	6.1	0.2	6.0	6.5	17.5	2.0	52.8	0.5	13.3	0.8	2.8	2.8	2.7	3.2	0.7	8.9	0.1	0.0	6.6	0.1	4.1	0.0	0.7	0.4	6.5	0.7	7.0	2.0	5.6	7.3	0.8	2.1	9.7	5.5	0.5	7.5	0.3	1.1	1.7	2.4	24.7	29.0	38.4	47.1	25.3	20.5	28.0	26.0	25.4	30.1	11.9	14.1	3.4	58.6	35.3	99.1	43.9	35.7	2.7	5.7	34.9	39.3	22.1	13.3	8.5	123.6	24.1	0.0	0.0	6.6	8.1	75.7	48.4	9.2	51.3	13.1	127.1	11.5	49.7	15.8	256.1	134.9	9.9	148.5	2.8	3.1	186.2	8.9	1.9	114.5	30.7	63.2	77.6	43.8	164.4	36.6	22.1	19.8	19.2	3.0	26.5
CTSG	CG	ENSG00000100448	"Cathepsin G"	P08311	14	24573522-24576260	"Enzymes, Plasma proteins, Predicted intracellular proteins"		"Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	19	"bone marrow: 450.3"	"Cell type enriched"	"Detected in some"	9	"granulocytes: 500.2"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"classical monocyte: 6.5;memory CD8 T-cell: 3.5;myeloid DC: 5.1;naive CD8 T-cell: 1.8;neutrophil: 7.1;NK-cell: 5.2;plasmacytoid DC: 5.7"	"Low lineage specificity"	"Detected in many"			"Cell line enriched"	"Detected in some"	7	"THP-1: 448.1"	"Not detected"	"Not detected"							"CAB000110, HPA047737"	Enhanced				"Intracellular and membrane"	NA	NA		67000			"CAB000110: , HPA047737: AB_2680140"	"unprognostic (1.67e-1)"	"unprognostic (2.57e-2)"	"unprognostic (6.92e-2)"	"unprognostic (1.08e-1)"		"prognostic favorable (1.57e-4)"	"unprognostic (4.05e-2)"	"unprognostic (4.13e-2)"	"unprognostic (3.06e-1)"	"unprognostic (2.42e-1)"	"unprognostic (2.60e-2)"	"unprognostic (2.05e-2)"	"unprognostic (1.63e-3)"	"unprognostic (1.07e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (8.91e-4)"	15.1	0.5	0.0	6.0	0.0	450.3	6.0	0.0	0.6	10.0	5.1	0.0	2.8	1.1	6.2	19.7	6.4	0.8	16.7	23.4	0.0	0.0	2.1	2.0	9.2	3.7	0.0	0.0	1.5	3.4	0.8	0.5	3.0	0.0	8.2	3.2	2.6	6.3	6.9	1.1	19.5	8.9	14.9	0.0	10.7	3.2	2.8	0.0	15.6	0.5	12.0	5.1	2.9	3.3	0.0	5.7	7.1	6.5	5.2	3.5	12.9	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.1	2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	448.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	66.4	0.0	0.0	6.5	0.0	1.1	1.0	0.0	0.0	1.0	3.5	5.1	0.0	0.0	1.8	7.1	5.2	0.0	5.7	0.0	12.9	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	11.9	58.0	0.0	0.0	5.7	0.0	0.6	0.0	1.4	4.5	0.0	0.0	0.0	0.0	0.0	3.5	0.0	0.0	0.0	0.0	0.1	1.0	0.0	500.2	0.0	0.2	0.0	0.0	0.0	0.0	4.7	0.0	4.7	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	3.4	0.0	0.0	0.0	0.0
CTSH	"ACC-4, ACC-5, ACC4, ACC5, CPSB"	ENSG00000103811	"Cathepsin H"	P09668	15	78921058-78949574	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lung: 82.6"	"Cell type enhanced"	"Detected in many"	9	"Alveolar cells type 2: 1152.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"classical monocyte: 42.8"	"Group enriched"	"Detected in all"	5	"B-cells: 20.6;dendritic cells: 41.2;monocytes: 42.8"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 43.1;HaCaT: 31.5;OE19: 31.0;RT4: 119.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB000458, HPA003524"	Enhanced		Supported	"Vesicles,Cytosol,Cytoplasmic bodies"	"Intracellular and membrane"	NA	NA		10000000	"Vesicles, Cytosol, Cytoplasmic bodies"		"CAB000458: , HPA003524: AB_1846075"	"unprognostic (6.47e-2)"	"unprognostic (4.65e-3)"	"unprognostic (1.05e-1)"	"prognostic favorable (6.90e-4)"	"unprognostic (4.37e-2)"	"unprognostic (1.93e-1)"	"unprognostic (7.18e-2)"	"unprognostic (3.30e-3)"	"unprognostic (2.22e-1)"	"unprognostic (5.96e-2)"	"unprognostic (4.10e-2)"	"unprognostic (3.89e-2)"	"unprognostic (6.63e-3)"	"unprognostic (3.83e-1)"	"unprognostic (4.42e-2)"	"unprognostic (2.70e-3)"	"unprognostic (1.79e-3)"	16.7	10.6	9.5	24.2	7.0	5.4	23.9	4.5	9.8	25.1	11.4	17.7	14.7	10.6	10.3	17.1	7.8	13.1	29.2	16.5	14.8	6.7	66.7	18.7	82.6	65.4	12.1	11.6	14.6	25.8	12.3	6.5	7.7	9.4	18.6	6.6	6.7	15.4	15.9	7.0	13.5	16.6	9.8	10.8	20.3	15.6	6.7	15.7	6.6	8.5	4.8	34.8	39.6	13.5	20.6	41.2	1.4	42.8	1.3	7.6	27.3	16.2	1.1	0.4	4.8	1.1	0.0	5.3	1.6	0.6	2.8	1.5	7.1	43.1	5.7	1.8	0.1	3.1	31.5	2.0	7.8	2.3	24.0	0.1	0.1	0.2	16.5	1.7	0.0	1.1	0.8	2.2	0.0	0.0	11.8	0.2	0.7	11.6	0.0	3.9	1.7	3.7	10.0	1.2	31.0	0.3	0.0	0.3	0.9	9.9	119.7	0.5	1.2	7.0	3.9	9.7	2.3	1.6	5.4	2.2	0.0	1.0	0.0	0.7	0.1	12.4	3.1	0.0	10.5	1.7	0.0	42.8	0.4	1.4	28.3	7.6	20.6	4.1	2.1	41.2	12.0	0.4	0.7	1.4	1.3	17.0	4.2	3.1	27.3	9.5	7.0	4.5	9.8	14.8	6.7	12.1	11.6	9.4	15.7	220.3	1152.3	144.6	210.0	21.5	0.8	25.2	351.6	270.4	197.9	349.0	3.9	16.6	71.3	153.3	17.1	109.7	15.8	0.0	128.8	33.6	30.0	89.1	30.2	82.9	261.0	0.0	8.7	15.4	160.1	15.9	67.6	392.5	75.9	476.1	19.5	21.1	69.6	11.5	5.6	352.9	5.6	19.4	17.8	5.0	52.9	16.3	19.6	25.4	37.0	308.4
CTSK	"CTSO, CTSO2, PKND, PYCD"	ENSG00000143387	"Cathepsin K"	P43235	1	150796208-150808323	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Hydrolase, Protease, Thiol protease"	"Disease mutation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 104.1"	"Cell type enhanced"	"Detected in many"	11	"Basal keratinocytes: 61.1;Leydig cells: 110.1;Melanocytes: 92.8;Peritubular cells: 140.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"classical monocyte: 6.7"	"Lineage enriched"	"Detected in many"	6	"monocytes: 6.7"	"Group enriched"	"Detected in some"	8	"ASC diff: 205.0;ASC TERT1: 75.1;BJ hTERT+: 165.6"	"Low region specificity"	"Detected in all"							HPA050346			Supported	Vesicles	"Intracellular and membrane"	NA	NA			Vesicles		"HPA050346: AB_2681101"	"unprognostic (1.48e-1)"	"unprognostic (9.29e-2)"	"unprognostic (1.21e-1)"	"unprognostic (7.61e-3)"	"unprognostic (5.08e-2)"	"unprognostic (6.57e-2)"	"unprognostic (1.02e-1)"	"unprognostic (6.60e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.54e-2)"	"prognostic unfavorable (7.12e-5)"	"unprognostic (6.07e-3)"	"unprognostic (2.98e-2)"	"unprognostic (5.93e-3)"	"unprognostic (6.41e-2)"	104.1	2.4	1.2	6.5	1.6	1.3	79.3	2.4	2.3	70.6	23.6	2.2	10.1	2.7	72.5	25.9	26.5	12.5	53.4	14.7	1.1	1.1	3.4	1.8	8.7	10.4	1.1	1.7	25.4	2.9	0.3	3.0	30.6	2.6	24.2	11.5	56.0	10.9	6.8	19.9	44.0	11.0	26.9	2.0	5.6	8.6	24.1	0.9	1.1	7.1	13.2	10.7	38.0	48.2	0.1	1.0	1.0	6.7	0.5	1.2	1.8	0.1	0.1	0.4	0.3	205.0	75.1	0.2	5.8	165.6	0.4	0.9	0.0	0.1	0.1	0.2	11.4	0.0	0.2	0.0	0.1	0.2	0.1	0.1	0.3	0.1	0.0	1.1	0.1	0.4	14.9	0.5	4.6	0.1	13.1	0.6	0.1	0.0	0.5	0.4	0.3	0.0	0.7	1.1	0.2	0.1	0.0	0.1	0.0	0.4	0.1	0.1	0.7	0.3	0.0	3.1	0.9	0.2	0.2	0.4	0.2	0.1	0.2	0.3	0.7	0.5	1.1	17.4	0.0	1.0	0.0	6.7	1.0	0.7	3.4	0.2	0.0	0.6	0.2	0.4	0.1	0.3	0.5	0.6	0.5	2.0	1.0	1.2	1.8	1.2	1.6	2.4	2.3	1.1	1.1	1.1	1.7	2.6	0.9	3.0	5.8	0.0	0.5	61.1	8.4	1.2	2.5	2.7	5.7	3.5	3.9	1.0	0.0	1.1	0.8	5.2	1.1	0.0	0.2	1.9	31.5	0.9	0.0	0.0	19.2	3.2	1.2	9.8	3.7	1.7	110.1	6.6	92.8	2.8	1.9	2.4	1.3	0.6	140.7	0.0	7.8	12.9	47.6	1.4	0.7	51.7	0.8	0.0	0.9	0.5
CTSL	"CTSL1, FLJ31037"	ENSG00000135047	"Cathepsin L"	P07711	9	87725519-87731393	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"placenta: 237.0"	"Cell type enhanced"	"Detected in all"	8	"Cytotrophoblasts: 935.7;Extravillous trophoblasts: 843.2;Hofbauer cells: 1004.8;Ito cells: 672.8;Syncytiotrophoblasts: 1290.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	9	"intermediate monocyte: 31.0;non-classical monocyte: 44.3"	"Lineage enriched"	"Detected in many"	10	"monocytes: 44.3"	"Cell line enhanced"	"Detected in many"		"ASC TERT1: 201.6;HSkMC: 93.2"									"CAB000459, HPA070413"	Enhanced		Approved	"Golgi apparatus,Vesicles"	"Intracellular and membrane"	NA	NA		17000000	"Golgi apparatus, Vesicles"		"CAB000459: AB_2292484, HPA070413: "	"unprognostic (1.05e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.24e-2)"	"unprognostic (1.53e-1)"	"prognostic unfavorable (3.73e-4)"	"unprognostic (1.19e-3)"	"unprognostic (8.12e-3)"	"prognostic unfavorable (5.15e-5)"	"unprognostic (2.09e-1)"	"unprognostic (3.15e-1)"	"unprognostic (6.80e-2)"	"unprognostic (3.21e-1)"	"prognostic favorable (4.34e-4)"	"unprognostic (5.64e-3)"	"unprognostic (2.26e-2)"	"unprognostic (1.72e-1)"	"unprognostic (7.11e-3)"	60.3	21.5	10.4	27.2	24.6	18.4	23.3	6.9	12.3	14.8	23.2	14.1	13.7	9.0	24.1	22.3	11.4	25.7	20.7	37.7	10.7	11.4	65.4	98.0	53.1	80.5	18.9	7.7	25.0	14.3	18.8	18.0	237.0	18.4	19.4	13.0	23.2	22.0	23.5	29.3	9.1	12.0	36.6	16.1	108.1	17.5	14.1	15.7	6.8	19.2	9.4	10.1	41.3	26.5	0.0	1.7	0.1	44.3	0.0	4.3	2.4	6.4	37.4	2.6	4.4	47.1	201.6	15.7	20.8	60.7	17.9	22.4	3.6	5.9	0.0	9.8	26.9	56.7	5.5	3.4	6.8	14.8	0.1	3.3	1.1	10.6	8.7	30.5	0.0	4.5	93.2	11.4	29.2	11.4	15.6	14.1	0.0	12.1	0.0	25.7	10.8	0.0	0.7	4.9	10.1	7.1	1.5	1.5	0.0	12.5	3.4	3.7	4.6	4.3	9.8	23.9	15.6	1.1	7.4	22.0	16.0	8.7	58.4	8.8	1.6	6.0	0.0	58.7	0.0	5.2	0.1	3.5	0.1	0.0	31.0	0.0	0.0	1.8	0.0	1.7	0.0	4.3	0.3	0.1	0.0	44.3	0.1	0.3	2.4	10.4	24.6	6.9	11.7	10.7	11.4	18.9	7.7	18.4	15.7	38.7	60.6	38.5	79.1	33.5	37.4	87.3	84.1	56.2	38.7	71.5	17.7	935.7	23.2	77.5	3.5	75.9	8.6	46.7	82.1	843.2	226.1	43.7	27.8	100.7	1004.8	12.7	11.1	672.8	182.1	10.4	145.3	481.4	60.8	19.8	7.7	78.6	55.2	2.9	176.0	107.8	35.6	90.5	103.2	144.4	46.2	29.6	1290.9	15.3	8.8	43.0
CTSO	CTSO1	ENSG00000256043	"Cathepsin O"	P43234	4	155924118-155953917	"Enzymes, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC TERT1: 12.5;HSkMC: 14.8;Karpas-707: 27.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002041	Approved				"Intracellular and membrane"	NA	NA		24000			"HPA002041: AB_1078408"	"unprognostic (3.96e-3)"	"unprognostic (1.62e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.33e-2)"	"unprognostic (9.10e-3)"	"unprognostic (2.55e-1)"	"unprognostic (3.80e-3)"	"unprognostic (2.07e-1)"	"unprognostic (6.62e-2)"	"unprognostic (1.33e-1)"	"unprognostic (2.20e-1)"	"unprognostic (1.05e-1)"	"unprognostic (7.55e-2)"	"unprognostic (4.87e-3)"	"unprognostic (4.73e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.79e-1)"	13.7	16.4	11.9	12.6	12.0	1.8	14.9	3.7	12.4	16.0	18.5	11.6	10.2	13.3	19.3	27.3	10.8	15.6	16.9	19.7	9.7	8.6	21.2	41.6	26.4	19.4	10.2	6.7	16.3	10.7	13.6	9.4	18.7	9.7	16.1	9.8	24.0	13.8	16.8	5.9	6.2	27.5	14.4	11.4	19.3	10.8	9.0	7.7	5.5	17.1	10.2	10.3	12.4	12.5	7.0	8.9	5.3	14.8	12.0	10.9	8.9	0.3	0.2	1.5	1.6	5.7	12.5	0.0	3.6	7.2	1.3	1.8	0.0	4.6	0.0	0.7	2.4	0.4	0.0	0.0	0.3	0.9	5.3	0.1	0.4	0.0	0.0	5.9	0.7	0.1	14.8	1.3	0.8	0.6	8.4	1.2	0.2	0.0	27.8	4.1	0.3	0.3	0.1	0.3	0.2	0.2	1.7	0.3	1.7	5.4	2.3	0.2	1.7	0.9	3.0	1.1	0.8	1.5	1.0	2.1	4.4	0.2	0.4	1.2	3.2	0.0	0.0	7.9	0.0	5.9	5.3	12.0	0.8	7.9	14.8	10.9	5.8	6.1	7.3	8.9	7.0	6.7	6.8	0.5	12.0	10.7	8.3	6.8	8.9	11.9	12.0	3.7	12.4	9.7	8.6	10.2	6.7	9.7	7.7	35.7	17.3	20.1	9.8	9.3	6.6	4.8	35.7	12.0	14.8	24.4	2.0	16.9	11.6	16.2	0.4	26.9	14.2	0.0	17.8	5.0	32.5	16.5	8.1	50.0	15.1	4.8	6.4	36.8	29.9	0.4	28.1	17.9	28.7	13.6	10.0	15.8	12.5	7.0	23.7	8.4	1.3	19.4	16.4	0.2	1.1	8.0	8.8	13.1	5.6	7.8
CTSS		ENSG00000163131	"Cathepsin S"	P25774	1	150730196-150765957	"Enzymes, Plasma proteins, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 171.4;lymphoid tissue: 111.4"	"Cell type enhanced"	"Detected in many"	13	"Hofbauer cells: 672.3;Kupffer cells: 1992.4;Macrophages: 1161.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	7	"classical monocyte: 171.4;intermediate monocyte: 151.2;myeloid DC: 43.5;neutrophil: 94.5;non-classical monocyte: 138.5"	"Group enriched"	"Detected in all"	9	"dendritic cells: 43.5;granulocytes: 94.5;monocytes: 171.4"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 21.6;HMC-1: 51.4;U-698: 109.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000460, HPA002988"	Supported		Approved	Vesicles	"Intracellular and membrane"	NA	NA		19000000	Vesicles		"CAB000460: , HPA002988: AB_1078409"	"unprognostic (7.81e-2)"	"unprognostic (9.04e-2)"	"unprognostic (3.23e-2)"	"unprognostic (3.93e-2)"	"unprognostic (1.52e-1)"	"unprognostic (1.12e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.23e-1)"	"unprognostic (1.59e-1)"	"unprognostic (6.00e-3)"	"unprognostic (1.46e-1)"	"unprognostic (3.89e-1)"	"unprognostic (6.24e-2)"	"unprognostic (7.50e-2)"	"unprognostic (4.14e-2)"	"unprognostic (2.13e-1)"	"unprognostic (2.47e-3)"	41.6	9.3	6.8	32.3	10.3	30.3	9.7	1.9	6.2	4.7	32.9	6.6	5.6	19.6	3.7	12.9	8.8	10.7	15.9	17.3	6.4	5.1	9.6	21.5	55.8	99.5	12.6	2.3	7.6	6.4	0.4	3.4	14.4	9.3	7.5	33.4	6.5	12.9	3.3	3.5	3.8	38.0	6.8	17.1	111.4	13.8	3.8	9.5	12.9	7.6	4.6	22.8	21.5	5.3	11.1	43.5	94.5	171.4	3.3	5.6	145.4	1.0	3.3	0.0	0.0	0.4	0.3	0.3	0.0	3.3	0.2	0.6	0.0	21.6	14.9	1.6	0.1	6.1	0.4	0.0	0.1	0.0	8.3	0.0	6.5	0.1	0.0	0.0	8.9	51.4	0.6	0.0	1.9	0.1	0.1	1.2	0.0	0.6	13.0	0.4	0.0	0.0	6.3	0.0	0.0	0.0	3.7	1.2	18.2	4.0	3.2	0.0	0.1	0.2	0.9	0.3	0.0	0.0	18.2	1.8	1.3	0.2	0.0	0.3	9.0	0.8	109.3	7.6	9.6	0.8	1.2	171.4	16.5	3.2	151.2	3.9	11.1	3.9	3.8	43.5	10.2	3.9	3.6	94.5	3.3	138.5	9.4	5.6	145.4	6.8	10.3	1.9	6.2	6.4	5.1	12.6	2.3	9.3	9.5	101.3	167.2	252.8	20.8	15.0	2.0	3.0	84.1	518.0	134.2	40.1	11.8	3.1	0.0	145.4	5.3	35.1	277.5	0.0	157.6	3.9	26.3	16.7	100.8	19.5	672.3	0.0	40.9	64.4	1992.4	1.7	4.9	1161.7	54.0	251.5	198.9	0.3	150.7	378.7	2.1	4.2	4.1	19.4	7.6	0.2	0.4	13.6	5.1	117.4	149.8	109.8
CTSV	"CTSL2, CTSU"	ENSG00000136943	"Cathepsin V"	O60911	9	97029679-97039643	"Enzymes, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"lymphoid tissue: 154.7"	"Cell type enhanced"	"Detected in many"	12	"Cytotrophoblasts: 114.1;Extravillous trophoblasts: 136.0;Syncytiotrophoblasts: 56.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	6	"NK-cell: 4.2;plasmacytoid DC: 15.7"	"Group enriched"	"Detected in many"	42	"dendritic cells: 15.7;NK-cells: 4.2"	"Group enriched"	"Detected in many"	9	"BEWO: 92.0;SuSa: 118.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB017112	Uncertain		Approved	"Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA		260000	"Nucleoli fibrillar center, Cytosol"	"Nucleoplasm, Plasma membrane"	"CAB017112: "	"unprognostic (2.40e-1)"	"unprognostic (2.74e-2)"	"unprognostic (1.50e-1)"	"prognostic favorable (8.41e-4)"	"unprognostic (7.29e-2)"	"unprognostic (5.59e-2)"	"prognostic unfavorable (2.83e-5)"	"unprognostic (7.04e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.39e-2)"	"prognostic unfavorable (2.87e-4)"	"unprognostic (1.86e-2)"	"unprognostic (1.78e-1)"	"unprognostic (2.41e-2)"	"unprognostic (1.33e-1)"	"unprognostic (3.04e-3)"	"prognostic unfavorable (2.39e-4)"	0.7	0.0	0.4	0.6	0.7	0.0	3.5	0.4	1.0	23.0	1.4	2.0	0.4	0.5	1.5	1.5	9.8	0.6	0.5	0.2	0.8	0.6	9.7	0.4	0.6	0.2	1.5	0.7	0.4	1.1	1.1	0.9	8.7	1.6	0.5	1.6	4.3	5.0	0.6	0.5	25.0	0.6	0.2	3.0	0.2	1.1	32.4	1.0	154.7	0.7	6.3	2.7	0.2	9.9	0.2	15.7	0.2	0.0	4.2	0.0	0.1	5.9	1.8	2.0	5.3	0.1	0.0	92.0	0.0	0.0	1.3	1.0	12.1	5.9	0.0	0.5	0.0	8.8	11.4	9.8	7.2	1.9	0.0	1.3	0.2	0.6	1.8	0.0	0.0	0.8	0.0	2.4	0.3	0.3	0.1	0.4	1.7	0.2	0.0	2.3	2.2	0.1	0.0	12.2	12.0	1.7	0.0	4.4	0.1	1.8	0.7	0.5	0.9	6.0	2.1	2.1	118.9	3.8	0.7	0.0	0.3	6.0	0.0	0.6	1.2	3.2	0.1	0.3	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.2	0.0	0.0	0.2	4.2	0.0	15.7	0.0	0.1	0.4	0.7	0.4	1.0	0.8	0.6	1.5	0.7	1.6	1.0	0.0	0.6	1.5	13.2	27.0	4.4	0.8	0.0	0.0	3.4	1.8	9.8	114.1	1.7	1.2	1.5	1.5	1.2	0.0	0.7	136.0	2.6	7.1	0.0	0.0	11.8	0.0	1.7	0.6	0.0	9.6	3.7	1.6	0.0	0.0	0.9	4.5	0.6	1.7	1.1	11.1	26.0	6.5	0.8	34.6	32.6	10.5	56.3	0.0	3.7	6.4
CTSW		ENSG00000172543	"Cathepsin W"	P56202	11	65879809-65883741	"Enzymes, Plasma proteins, Predicted secreted proteins"		"Hydrolase, Protease, Thiol protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood: 157.2;bone marrow: 41.4"	"Group enriched"	"Detected in many"	10	"granulocytes: 70.4;T-cells: 273.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	8	"gdT-cell: 106.6;MAIT T-cell: 67.7;memory CD8 T-cell: 68.3;naive CD8 T-cell: 51.4;NK-cell: 157.2"	"Group enriched"	"Detected in many"	48	"NK-cells: 157.2;T-cells: 106.6"	"Group enriched"	"Detected in some"	23	"HEL: 38.8;NB-4: 88.8"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in some"			CAB016345	Enhanced				"Secreted to blood"	NA	NA		340000			"CAB016345: AB_626813"	"prognostic favorable (3.06e-4)"	"unprognostic (2.06e-2)"	"unprognostic (2.71e-2)"	"prognostic favorable (8.36e-6)"	"unprognostic (1.21e-1)"	"prognostic favorable (9.89e-4)"	"unprognostic (5.69e-2)"	"unprognostic (1.09e-2)"	"unprognostic (1.25e-3)"	"unprognostic (5.14e-3)"	"unprognostic (2.83e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (8.84e-6)"	"unprognostic (3.86e-2)"	"unprognostic (3.78e-1)"	"unprognostic (1.26e-1)"	"unprognostic (4.01e-3)"	5.2	1.2	0.9	4.9	1.0	41.4	2.3	0.6	0.7	3.9	4.9	0.8	0.5	2.4	8.4	4.0	2.1	2.1	2.5	9.0	0.9	1.0	2.5	6.8	12.7	36.0	1.1	0.6	3.0	1.1	0.0	1.4	10.7	1.4	7.4	2.5	6.3	10.9	1.5	1.9	1.5	5.9	1.7	2.1	33.1	3.3	3.4	0.4	11.1	3.1	1.3	18.2	4.5	2.6	0.4	2.7	2.3	0.3	157.2	106.6	45.7	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	38.8	0.0	0.0	0.0	2.7	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	2.2	0.0	0.0	0.4	88.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	1.3	0.0	0.0	0.0	0.1	0.3	0.1	0.1	0.0	0.0	2.4	0.0	2.3	0.2	0.3	106.6	0.2	67.7	0.4	11.7	68.3	2.7	0.3	7.0	51.4	2.0	157.2	0.3	1.7	1.6	45.7	0.9	1.0	0.6	0.7	0.9	1.0	1.1	0.6	1.4	0.4	0.0	6.2	3.7	0.4	4.0	0.0	0.4	0.0	1.4	2.3	0.0	0.0	0.1	0.0	0.2	1.8	0.6	0.0	0.0	0.0	0.1	3.2	0.3	70.4	1.7	1.9	0.0	0.0	5.5	5.3	8.8	0.0	7.3	16.9	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.8	0.2	0.9	5.5	0.2	273.8	0.0	0.3
CTSZ	CTSX	ENSG00000101160	"Cathepsin Z"	Q9UBR2	20	58995185-59007247	"Enzymes, Plasma proteins, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"	11	"Hofbauer cells: 945.4;Macrophages: 462.5;monocytes: 1072.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"classical monocyte: 3.2;intermediate monocyte: 2.7;memory B-cell: 1.0;myeloid DC: 3.9;naive B-cell: 1.9;neutrophil: 3.5;non-classical monocyte: 2.9;plasmacytoid DC: 2.2"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 119.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB025114, HPA049876, HPA053504"	Supported		Supported	Vesicles	"Intracellular and membrane"	NA	NA		85000000	Vesicles		"CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172"	"unprognostic (7.30e-2)"	"unprognostic (3.98e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.11e-3)"	"unprognostic (8.25e-3)"	"unprognostic (1.15e-1)"	"unprognostic (4.12e-2)"	"unprognostic (6.59e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.33e-1)"	"unprognostic (5.33e-2)"	"prognostic unfavorable (5.72e-5)"	"unprognostic (1.96e-1)"	"unprognostic (6.92e-2)"	"unprognostic (1.19e-1)"	"unprognostic (2.04e-1)"	70.7	27.9	12.4	40.8	20.4	20.7	51.2	14.6	13.5	25.4	52.8	16.0	19.9	40.8	20.6	25.5	20.1	20.7	22.3	50.1	9.8	13.3	34.9	83.7	54.3	61.2	18.8	10.5	29.7	29.0	30.6	27.6	38.6	19.2	28.8	37.8	31.5	40.3	17.7	20.7	12.9	63.6	26.4	22.1	56.5	19.2	13.8	14.9	18.4	42.4	17.5	35.8	29.8	21.5	1.9	3.9	3.5	3.2	0.3	0.6	0.8	27.6	21.5	0.0	0.0	25.4	29.2	15.2	45.5	50.4	34.9	31.2	41.5	46.5	15.2	30.2	119.6	0.0	22.1	13.7	43.1	23.9	48.6	1.8	13.9	34.8	0.0	26.6	1.6	48.4	24.8	26.0	15.2	18.2	11.6	55.2	0.0	10.0	7.7	23.3	0.0	0.1	15.0	1.7	12.1	21.5	0.3	0.1	18.2	25.5	6.5	0.4	0.3	35.4	41.0	0.1	14.2	18.9	23.6	60.6	0.0	23.6	30.7	0.2	36.7	22.3	2.9	0.4	33.5	0.0	0.0	3.2	0.3	0.6	2.7	0.0	1.0	0.4	0.1	3.9	1.9	0.4	0.1	3.5	0.3	2.9	2.2	0.2	0.8	12.4	20.4	14.6	13.5	9.8	13.3	18.8	10.5	19.2	14.9	14.9	4.0	130.0	51.2	44.8	4.6	17.5	53.5	8.1	5.7	68.0	0.0	34.5	19.9	168.0	2.8	62.8	285.7	23.3	37.2	91.0	58.0	41.9	10.4	307.7	945.4	11.1	26.0	44.2	260.7	3.3	12.0	462.5	96.2	1072.2	50.0	45.9	72.3	98.2	13.1	68.2	4.9	45.3	59.0	1.7	4.5	36.3	34.6	29.9	76.8	46.2
HACD1	"CAP, PTPLA"	ENSG00000165996	"3-hydroxyacyl-CoA dehydratase 1"	B0YJ81	10	17589032-17617377	"Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	"Developmental protein, Lyase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 80.1"	"Cell type enhanced"	"Detected in many"	16	"Cardiomyocytes: 116.4;Collecting duct cells: 29.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	10	"T-reg: 27.6"	"Lineage enriched"	"Detected in many"	16	"T-cells: 27.6"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA						"unprognostic (2.73e-2)"	"unprognostic (3.26e-2)"	"unprognostic (3.54e-1)"	"unprognostic (2.62e-2)"	"unprognostic (4.10e-1)"	"unprognostic (5.67e-3)"	"unprognostic (4.21e-2)"	"unprognostic (3.04e-2)"	"unprognostic (2.38e-1)"	"unprognostic (1.70e-2)"	"unprognostic (2.61e-2)"	"unprognostic (3.43e-1)"	"unprognostic (2.46e-2)"	"unprognostic (2.93e-2)"	"unprognostic (3.40e-2)"	"unprognostic (1.10e-1)"	"unprognostic (6.49e-2)"	6.6	4.7	2.1	3.8	3.9	5.4	12.6	3.4	3.1	5.1	17.6	3.9	7.4	2.3	13.1	6.0	12.6	6.5	4.8	80.1	2.4	3.7	3.6	1.1	7.9	1.1	5.1	1.8	3.9	2.5	0.6	2.4	1.5	3.8	8.8	3.3	9.4	2.1	13.2	22.8	2.5	4.2	21.5	4.8	1.5	9.4	3.0	3.4	2.6	5.9	6.2	1.2	12.6	9.8	0.6	1.6	1.7	0.5	1.6	27.6	0.7	10.8	9.3	2.6	12.8	11.9	2.3	0.2	15.4	9.3	20.2	19.1	6.2	13.2	0.1	2.3	25.0	29.1	2.7	6.6	4.7	11.2	7.1	3.9	25.0	6.7	16.9	15.5	0.1	1.9	5.5	6.6	11.6	4.5	15.6	3.9	13.4	0.2	0.5	26.5	7.8	18.4	2.5	5.6	0.8	2.5	16.6	2.7	0.3	7.9	2.1	2.9	7.5	13.1	0.2	21.6	8.6	9.3	6.2	3.7	11.9	6.9	7.2	7.0	0.4	0.3	0.1	8.7	2.8	1.6	1.7	0.5	0.4	0.6	0.1	0.1	0.2	2.8	0.5	1.6	0.6	0.5	0.4	1.6	1.6	0.1	0.8	27.6	0.7	2.1	3.9	3.4	2.8	2.4	3.7	5.1	1.8	3.8	3.4	26.8	12.9	0.0	16.5	0.0	0.6	116.4	2.5	1.4	4.5	29.6	0.0	0.5	3.3	13.0	8.3	4.8	0.0	0.0	6.9	1.6	2.3	12.0	5.8	0.8	5.0	0.0	3.5	11.6	3.5	1.6	1.7	2.4	0.0	1.0	2.3	0.2	18.1	0.0	0.7	2.0	0.5	0.0	25.7	5.5	5.1	0.0	2.5	0.0	3.8	5.5
HACD2	PTPLB	ENSG00000206527	"3-hydroxyacyl-CoA dehydratase 2"	Q6Y1H2	3	123490820-123585185	"Enzymes, Predicted membrane proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SiHa: 65.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019282	Approved					NA	NA					"CAB019282: "	"unprognostic (3.04e-2)"	"unprognostic (2.51e-1)"	"unprognostic (6.11e-2)"	"unprognostic (2.65e-3)"	"unprognostic (5.36e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.32e-2)"	"unprognostic (1.95e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.22e-1)"	"prognostic unfavorable (9.59e-5)"	"unprognostic (6.90e-2)"	"unprognostic (7.03e-3)"	"unprognostic (1.48e-1)"	"unprognostic (3.85e-2)"	"unprognostic (1.94e-2)"	"unprognostic (2.59e-2)"	43.2	9.7	18.0	11.2	30.0	5.7	16.6	20.5	18.7	14.1	20.4	28.6	7.4	21.2	12.4	13.5	18.8	9.9	12.2	9.9	20.7	13.4	20.7	34.3	13.8	14.1	29.4	12.0	13.8	13.4	15.6	12.5	11.1	18.5	22.1	20.4	7.3	15.5	10.2	5.6	23.2	30.8	12.3	24.9	9.6	15.3	13.3	25.7	9.1	16.0	10.5	19.7	10.9	16.6	4.9	6.4	2.4	3.5	2.9	5.3	2.4	19.6	11.2	7.7	5.6	24.2	5.4	28.7	14.1	5.9	14.7	10.7	22.8	17.5	11.4	10.2	13.5	17.1	43.2	13.8	17.7	15.6	7.2	4.6	7.9	10.5	17.7	7.9	10.5	7.9	7.5	45.7	7.1	20.0	23.1	7.6	7.9	1.6	11.4	8.8	15.3	4.9	3.1	9.9	24.0	9.9	7.6	8.5	12.1	17.8	12.7	13.6	4.2	65.7	14.1	9.0	11.7	14.6	5.4	5.9	15.4	11.6	15.4	13.7	6.8	8.6	9.4	6.9	7.4	8.2	1.5	3.5	2.4	3.6	2.8	5.3	3.4	4.8	4.6	6.4	4.9	4.4	4.3	1.1	2.9	2.2	3.7	5.3	2.4	18.0	30.0	20.5	18.7	20.7	13.4	29.4	12.0	18.5	25.7	6.0	35.5	13.7	26.4	0.0	8.3	12.6	15.3	5.3	28.4	43.6	5.9	20.9	6.6	13.4	12.7	13.7	18.6	0.0	16.5	13.3	10.4	36.8	3.5	42.9	20.1	1.6	15.2	14.7	20.2	7.3	10.6	17.1	0.0	16.2	21.7	13.5	16.4	21.0	16.6	13.9	12.9	6.5	8.8	8.1	20.5	0.0	5.6	11.7	24.7	26.3
LGMN	"LGMN1, PRSC1"	ENSG00000100600	Legumain	Q99538	14	92703807-92748702	"Cancer-related genes, Enzymes, Predicted intracellular proteins"		"Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"	15	"Hofbauer cells: 1236.6;Ito cells: 365.8;Syncytiotrophoblasts: 348.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	11	"plasmacytoid DC: 54.2"	"Lineage enriched"	"Detected in many"	11	"dendritic cells: 54.2"	"Cell line enhanced"	"Detected in many"		"RPMI-8226: 129.9;U-266/70: 71.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001426	Enhanced		Approved	Nucleoplasm,Vesicles	"Intracellular and membrane"	NA	NA		1200000	Vesicles	Nucleoplasm	"HPA001426: AB_1079247"	"unprognostic (1.19e-1)"	"unprognostic (1.16e-1)"	"unprognostic (2.37e-1)"	"unprognostic (1.52e-1)"	"unprognostic (1.99e-1)"	"unprognostic (3.29e-2)"	"unprognostic (4.52e-2)"	"unprognostic (1.31e-1)"	"unprognostic (5.03e-2)"	"unprognostic (3.50e-2)"	"unprognostic (4.70e-2)"	"unprognostic (2.47e-1)"	"prognostic favorable (4.70e-4)"	"unprognostic (8.06e-2)"	"unprognostic (3.64e-2)"	"unprognostic (7.18e-3)"	"unprognostic (7.24e-2)"	42.9	16.3	8.6	17.4	10.7	3.5	19.9	5.8	17.9	13.3	22.3	11.7	13.9	24.2	12.1	48.1	17.4	14.1	32.7	38.8	10.3	10.1	87.6	44.6	31.5	42.4	8.3	10.1	20.5	14.6	54.4	9.7	113.6	9.9	22.0	24.5	23.2	22.6	8.4	17.3	11.9	37.1	23.3	11.5	58.3	23.7	14.0	7.9	17.2	36.8	19.2	17.3	31.4	18.2	4.7	54.2	0.7	0.8	1.0	4.3	1.7	4.9	7.1	4.8	8.7	14.9	12.0	16.7	10.6	10.2	11.1	13.1	5.5	8.9	2.7	15.8	17.4	6.9	12.3	0.0	9.2	5.3	0.2	5.5	0.1	3.9	6.3	4.4	0.1	0.4	8.5	4.5	10.7	6.2	3.3	13.1	5.1	1.0	23.0	0.8	6.6	1.3	0.2	2.3	31.1	4.9	1.2	4.2	129.9	12.0	19.3	5.2	3.5	14.8	9.1	7.7	11.0	6.7	0.0	7.1	5.5	7.0	9.9	3.2	71.5	8.4	3.7	3.1	0.1	10.5	0.7	0.4	0.1	0.2	0.8	0.4	4.7	1.4	0.4	5.0	3.4	4.3	2.5	0.5	1.0	0.2	54.2	2.6	1.7	8.6	10.7	5.8	17.9	10.3	10.1	8.3	10.1	9.9	7.9	53.6	113.7	33.9	33.3	20.5	9.9	25.0	45.9	18.7	34.2	29.6	88.4	130.6	8.3	49.8	0.8	31.3	68.2	0.0	45.2	121.5	45.8	47.6	8.1	36.1	1236.6	12.7	35.1	365.8	242.3	2.3	28.1	82.0	45.5	62.3	31.1	25.8	41.2	52.6	54.5	101.8	15.3	19.4	64.6	22.3	17.7	15.3	348.2	8.5	40.4	39.9
NAPSA	"KAP, Kdap, NAP1, NAPA"	ENSG00000131400	"Napsin A aspartic peptidase"	O96009	19	50358477-50365830	"Enzymes, Plasma proteins, Predicted secreted proteins"		"Aspartyl protease, Hydrolase, Protease"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	10	"kidney: 47.5;lung: 153.3"	"Cell type enriched"	"Detected in many"	5	"Alveolar cells type 2: 2552.8"	"Cancer enriched"	"Detected in many"	18	"lung cancer: 249.9"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"plasmacytoid DC: 10.5"	"Group enriched"	"Detected in many"	9	"B-cells: 5.1;dendritic cells: 10.5"	"Cell line enriched"	"Detected in some"	24	"U-698: 29.8"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"CAB009591, HPA045280, HPA047236, HPA047744"	Enhanced				"Secreted in other tissues"	NA	NA		380000			"CAB009591: , HPA045280: AB_2679283, HPA047236: AB_2679993, HPA047744: AB_2680143"	"unprognostic (5.36e-2)"	"unprognostic (4.77e-2)"	"unprognostic (1.64e-3)"	"unprognostic (1.78e-1)"	"unprognostic (1.93e-1)"	"unprognostic (4.65e-2)"	"unprognostic (1.02e-1)"	"unprognostic (8.30e-3)"	"unprognostic (2.29e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.76e-3)"	"unprognostic (7.67e-3)"	"prognostic favorable (1.21e-4)"	"unprognostic (4.08e-4)"	"unprognostic (3.29e-1)"	"unprognostic (9.83e-3)"	"unprognostic (7.26e-5)"	0.1	0.1	0.1	0.2	0.1	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	5.0	0.1	0.1	0.1	0.1	0.1	0.0	47.5	0.1	153.3	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.5	0.3	0.1	0.0	0.1	0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.3	0.1	0.1	0.1	0.1	5.1	10.5	0.5	0.9	0.5	0.6	1.1	0.2	0.4	0.0	0.2	0.2	0.2	0.1	0.1	0.0	0.0	0.1	0.1	0.4	0.2	0.2	0.1	0.0	0.5	0.1	0.0	0.0	0.2	0.6	0.0	0.0	0.0	0.2	0.0	0.2	0.3	1.2	0.1	0.0	0.1	0.0	0.0	0.3	0.1	0.0	0.6	0.1	0.3	0.2	0.3	0.3	0.6	0.0	0.1	0.9	0.0	0.0	0.1	0.3	0.0	0.1	0.1	0.1	0.3	0.1	0.0	0.1	0.8	0.0	0.2	0.4	29.8	0.0	0.1	0.0	0.0	0.4	0.0	0.1	0.9	0.0	5.1	0.2	0.4	3.0	1.9	0.6	0.5	0.5	0.5	0.9	10.5	0.0	1.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.1	0.3	0.1	485.3	2552.8	8.0	0.4	0.1	1.3	0.4	0.0	29.4	84.2	43.6	3.9	0.4	8.3	0.4	34.9	0.1	0.9	0.0	0.7	0.2	0.2	0.6	64.0	0.0	0.3	0.0	0.0	0.0	0.3	4.5	0.9	4.0	0.0	0.0	0.9	1.3	0.1	2.8	0.4	230.9	0.7	0.0	0.3	0.5	0.7	0.5	0.1	0.0	0.8	0.0
TPP1	"CLN2, SCAR7"	ENSG00000166340	"Tripeptidyl peptidase 1"	O14773	11	6612763-6619485	"Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Hydrolase, Protease, Serine protease"	"Disease mutation, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"	7	"Hofbauer cells: 223.6;Kupffer cells: 312.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037709, HPA044868"	Enhanced				"Intracellular and membrane"	NA	NA		13000000			"HPA037709: AB_10672913, HPA044868: AB_2679122"	"unprognostic (8.27e-3)"	"unprognostic (5.85e-2)"	"unprognostic (7.12e-3)"	"unprognostic (3.34e-3)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (4.31e-4)"	"prognostic unfavorable (1.11e-4)"	"unprognostic (6.32e-2)"	"unprognostic (3.01e-1)"	"unprognostic (2.39e-2)"	"unprognostic (1.31e-1)"	"unprognostic (6.54e-2)"	"unprognostic (6.23e-2)"	"prognostic unfavorable (4.46e-4)"	"unprognostic (3.87e-2)"	"unprognostic (2.59e-1)"	"unprognostic (1.12e-2)"	37.4	64.6	32.2	28.8	36.2	43.0	23.1	15.1	33.3	24.0	26.8	41.7	13.2	28.0	32.0	22.3	20.3	18.0	26.9	25.6	24.5	25.1	36.0	45.1	35.9	42.3	31.0	29.3	22.0	14.8	35.1	30.0	56.4	25.4	19.4	28.2	43.4	18.4	29.1	15.4	15.5	31.4	42.4	32.8	69.0	19.8	17.9	24.7	21.7	24.0	9.1	26.9	25.6	29.4	9.4	43.5	12.8	38.9	7.0	15.3	26.2	4.8	9.8	4.9	9.3	57.7	31.9	3.8	9.5	45.1	7.4	12.9	4.0	20.7	6.9	6.3	24.0	45.7	14.5	9.7	13.3	11.2	6.9	5.6	5.6	5.1	10.9	43.6	8.1	34.2	47.8	21.7	8.6	19.2	49.8	31.5	6.5	10.7	21.0	21.6	6.0	2.5	10.0	3.5	11.4	11.8	6.3	4.1	13.6	13.1	7.6	0.6	3.8	10.2	7.6	17.8	16.9	5.0	15.5	36.0	21.4	6.1	19.2	3.4	17.8	17.4	2.4	27.1	19.0	11.2	12.8	37.7	8.9	10.7	38.9	8.7	9.4	8.5	11.0	43.5	8.5	5.8	7.6	6.9	7.0	26.4	24.2	15.3	26.2	32.2	36.2	15.1	33.3	24.5	25.1	31.0	29.3	25.4	24.7	23.8	31.2	61.7	25.6	21.1	22.8	35.0	58.6	10.7	23.9	15.7	11.8	31.4	5.0	32.3	10.2	39.0	51.3	23.3	11.7	36.7	29.8	25.6	62.2	63.8	223.6	14.3	16.0	90.9	312.0	7.8	25.0	115.7	86.0	64.1	29.1	42.4	18.5	39.0	24.8	46.1	22.8	6.5	22.7	0.5	1.1	17.6	73.6	44.8	28.0	23.0