Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 56.5" "Cell type enhanced" "Detected in many" 16 "Extravillous trophoblasts: 60.6;Hepatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favorable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.0 3.1 9.2 2.2 9.0 0.9 4.7 0.8 10.8 8.3 4.7 10.3 2.9 1.9 9.7 5.8 2.8 5.7 3.9 2.8 7.2 6.4 6.3 56.5 4.7 1.1 8.2 8.0 4.7 4.6 7.6 8.9 2.2 6.0 13.3 5.0 6.6 1.7 5.4 3.6 1.8 2.0 7.0 7.0 2.0 3.2 7.2 9.2 0.9 7.0 1.2 1.3 5.5 4.9 0.4 0.4 0.0 0.7 0.0 0.7 0.0 2.2 5.5 16.7 0.0 3.3 13.0 6.0 5.7 2.8 3.3 3.3 5.3 0.6 0.0 0.9 6.3 4.3 1.9 7.4 2.7 2.3 0.0 6.4 0.0 6.2 8.9 2.7 0.0 2.4 5.3 1.6 2.7 3.5 9.1 3.1 7.5 0.9 0.1 12.6 5.6 2.7 0.1 12.6 6.2 5.0 0.0 5.2 0.0 2.9 10.0 13.5 15.7 4.5 1.1 5.4 5.6 0.0 1.1 2.1 8.4 9.0 9.5 8.8 0.0 0.0 0.0 8.4 0.0 9.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.3 0.3 0.4 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 9.2 9.0 0.8 10.8 7.2 6.4 8.2 8.0 6.0 9.2 0.0 5.1 0.0 2.6 0.8 5.1 1.1 2.5 14.7 3.4 0.0 2.0 1.4 0.0 1.3 0.4 0.5 0.0 0.0 1.9 60.6 2.4 3.6 0.0 22.9 1.4 0.0 6.4 0.0 0.3 0.6 1.1 0.6 1.7 0.0 1.3 3.2 0.9 0.0 2.1 6.5 8.2 6.5 2.2 2.4 12.5 0.4 4.7 0.0 2.3 1.4 AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122075647-122144280 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Hepatocytes: 98.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.0;granulocytes: 3.5;T-cells: 1.2" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;NTERA-2: 25.0;SuSa: 21.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Enhanced Vesicles,Mitochondria Yes No 17000 Mitochondria Vesicles "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favorable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 13.9 9.5 7.4 4.8 11.8 1.6 11.2 2.7 9.8 16.0 8.1 12.5 8.2 2.2 16.8 11.6 6.4 14.9 6.7 12.6 8.8 3.7 14.4 35.8 9.1 3.3 15.2 5.0 36.7 10.7 14.9 10.4 7.1 9.9 9.2 3.8 9.2 5.4 10.4 11.3 4.4 5.5 9.3 12.1 5.2 9.0 5.1 13.2 0.8 7.8 8.3 3.1 11.0 9.0 1.0 0.4 3.5 0.1 0.3 1.2 0.1 0.1 0.0 15.8 25.6 13.3 8.5 6.2 4.3 4.6 4.5 6.5 7.3 0.2 0.0 0.2 3.0 5.1 2.7 18.3 8.2 6.2 0.0 6.7 5.5 3.5 4.7 10.8 0.0 1.8 7.5 0.2 5.4 5.7 12.6 10.8 7.3 1.4 10.1 3.1 0.0 0.5 0.0 25.0 0.0 1.0 8.3 8.4 0.3 2.1 1.7 1.6 0.5 1.4 0.0 2.6 21.7 0.4 0.0 4.9 8.8 2.7 4.1 4.1 2.2 1.6 0.0 3.2 0.5 3.4 3.5 0.1 0.0 0.7 0.0 0.1 0.5 0.8 0.0 0.4 1.0 1.2 0.5 0.0 0.3 0.0 0.0 0.7 0.1 7.4 11.8 2.7 7.3 8.8 3.7 15.2 5.0 9.9 13.2 8.9 28.6 1.5 8.9 5.6 6.3 8.1 7.6 0.0 7.9 14.0 15.7 9.1 0.0 1.8 9.2 9.2 1.0 0.0 1.5 2.5 9.3 5.2 3.5 98.3 1.2 11.1 2.9 19.6 1.8 5.4 17.5 1.5 11.8 0.0 2.4 8.7 2.6 2.9 23.0 7.8 2.2 19.4 21.6 6.4 1.5 4.1 4.2 2.2 1.5 3.7 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595418 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.4" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 364.8;Proximal tubular cells: 241.4;Syncytiotrophoblasts: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 140000 Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 9.0 14.2 46.0 3.4 39.1 0.8 18.8 11.0 22.5 14.0 11.5 23.1 7.2 9.5 10.5 7.5 13.5 11.9 7.8 10.8 35.0 17.3 46.5 64.4 6.4 3.1 28.7 18.5 27.6 10.8 17.7 5.9 17.7 16.9 17.6 11.2 13.7 15.0 12.2 4.5 11.9 8.1 9.8 20.2 2.8 9.0 4.9 28.4 4.0 19.4 10.1 7.4 7.2 7.1 1.3 9.7 0.7 0.3 0.1 1.8 0.6 15.0 10.0 28.3 46.8 23.5 14.0 36.1 18.1 22.4 21.1 27.2 28.0 14.5 0.0 18.5 14.1 8.8 11.3 8.8 61.1 19.4 0.0 10.6 2.9 14.9 23.8 11.5 0.0 0.0 17.1 14.4 16.4 11.8 15.6 16.8 0.0 0.0 0.0 18.5 9.9 0.6 0.0 19.1 11.1 8.5 9.0 32.1 0.0 20.0 11.5 9.6 11.5 0.0 10.0 10.5 22.7 18.0 0.6 20.4 6.1 18.9 7.0 12.4 0.0 0.0 0.0 3.3 0.0 9.8 0.7 0.3 0.1 0.2 0.0 0.3 1.3 0.3 0.2 2.7 1.1 1.8 1.0 0.3 0.1 0.0 9.7 0.1 0.6 46.0 39.1 11.0 22.5 35.0 17.3 28.7 18.5 16.9 28.4 14.9 24.0 11.8 48.6 23.0 22.4 35.5 25.5 20.1 33.0 40.1 21.6 364.8 64.6 31.9 24.9 14.7 17.8 0.0 12.1 88.6 30.8 28.6 6.9 69.5 42.5 23.8 20.8 20.9 9.4 29.5 23.6 7.4 52.3 12.6 22.1 96.8 15.1 8.6 35.0 241.4 12.2 19.4 17.3 1.0 3.1 14.1 185.9 2.5 43.7 34.8 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Muller glia cells: 289.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 1100000 Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 39.1 52.7 30.8 17.4 25.4 7.7 39.6 16.2 26.6 20.3 18.0 22.7 17.1 19.5 15.5 35.5 47.0 18.8 22.2 22.2 24.8 21.1 50.5 73.5 20.7 20.4 23.7 18.4 20.6 17.8 31.2 19.2 14.1 22.8 24.6 18.7 27.2 52.2 23.2 29.9 22.6 23.9 19.2 21.9 18.8 14.7 37.3 21.5 12.4 45.1 24.2 27.9 18.5 19.1 29.6 20.2 29.4 24.5 23.1 39.0 24.4 17.0 16.7 15.6 14.0 49.9 44.0 13.1 22.6 32.1 22.8 19.8 10.3 12.8 0.0 21.7 20.2 11.2 13.5 12.6 22.1 27.0 7.9 16.0 10.9 12.0 11.2 25.7 17.0 11.6 28.2 11.2 24.1 20.2 31.6 19.7 14.5 17.2 15.4 35.4 10.2 11.3 17.6 22.7 44.9 20.5 9.7 19.8 22.8 29.6 16.2 18.6 12.8 16.1 18.2 20.7 22.1 34.6 25.9 19.4 13.8 13.5 16.7 11.4 14.4 18.7 17.0 15.5 16.3 13.2 26.8 20.3 28.1 28.3 21.5 30.1 29.6 27.7 30.6 20.2 26.0 28.1 32.0 29.4 23.1 24.5 12.6 39.0 24.4 30.8 25.4 16.2 26.6 24.8 21.1 23.7 18.4 22.8 21.5 14.9 37.5 27.9 34.1 29.0 24.6 38.9 48.4 69.6 30.7 48.8 21.6 42.9 82.9 36.4 32.5 37.9 44.4 23.3 32.5 64.2 46.7 49.5 36.9 114.6 53.7 12.7 53.6 52.8 58.2 28.9 88.3 37.5 54.0 19.8 52.5 289.8 28.8 31.6 108.5 141.7 26.8 25.8 36.0 33.8 46.2 45.4 31.9 38.9 58.1 23.5 ASH1L "ASH1, ASH1L1, huASH1, KMT2H" ENSG00000116539 "ASH1 like histone lysine methyltransferase" Q9NR48 1 155335268-155562807 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004806 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Nucleoplasm, Golgi apparatus" "HPA004806: AB_1845087" "unprognostic (2.98e-1)" "unprognostic (3.15e-2)" "unprognostic (1.10e-1)" "unprognostic (1.70e-2)" "unprognostic (2.05e-2)" "unprognostic (4.75e-2)" "unprognostic (1.42e-1)" "unprognostic (1.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (1.07e-1)" "unprognostic (6.84e-2)" "prognostic favorable (3.80e-4)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (2.45e-2)" "unprognostic (1.94e-1)" 20.1 10.1 12.1 17.7 14.5 12.3 14.5 23.6 15.5 15.4 17.7 15.5 20.4 8.2 18.7 12.5 12.5 12.2 10.0 11.0 11.8 10.6 13.0 8.9 10.6 9.4 16.6 11.5 23.5 10.0 24.4 22.6 12.9 13.2 18.9 10.7 10.7 11.8 22.2 21.8 12.8 12.8 17.4 14.5 8.6 10.4 7.8 14.3 15.6 16.8 7.1 10.6 17.8 19.9 11.0 5.7 16.5 5.3 8.6 10.7 1.7 13.6 11.7 7.7 6.6 17.4 18.7 8.7 11.1 11.6 7.6 6.4 8.7 9.1 6.1 11.2 14.5 5.8 14.2 12.1 9.7 12.0 6.0 7.8 7.5 11.6 4.7 8.4 8.3 5.9 11.5 10.8 12.7 12.5 11.5 9.0 6.0 10.7 9.2 12.6 10.7 5.6 4.5 7.3 17.0 11.4 5.2 15.9 7.0 8.4 15.1 7.9 11.7 17.5 15.8 8.6 8.4 12.7 18.2 13.8 11.7 12.6 11.1 13.6 8.6 4.9 9.7 9.1 6.3 10.1 16.5 5.3 11.0 8.3 3.2 7.9 10.0 7.8 6.3 2.5 11.0 10.7 5.5 12.8 8.6 3.5 5.7 8.6 1.7 12.1 14.5 23.6 15.2 11.8 10.6 16.6 11.5 13.2 14.3 56.6 88.1 42.2 92.1 92.3 138.8 87.3 43.3 45.5 96.7 48.8 190.5 40.3 14.9 37.0 14.5 82.3 61.6 23.3 34.5 22.1 98.4 94.0 78.6 28.8 21.6 108.1 64.8 59.5 40.8 12.1 94.6 55.1 50.6 62.3 49.5 77.4 31.8 59.1 111.7 23.9 119.9 97.0 97.6 85.7 46.2 97.9 63.7 68.9 46.6 109.1 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 139.4;liver: 39.3" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1023.7" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTCEpi: 16.2;RPTEC TERT1: 10.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 25000 Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 0.9 0.5 9.2 0.5 7.1 0.5 8.2 3.9 7.5 1.5 0.6 4.9 0.1 0.5 0.6 3.6 5.7 3.8 3.6 0.5 7.9 6.3 139.4 39.3 0.6 0.6 10.9 4.3 0.5 0.8 0.5 8.3 1.3 9.2 0.7 0.5 0.0 2.2 2.0 0.6 16.4 0.5 0.5 7.1 0.5 0.6 0.6 5.8 0.0 8.9 1.6 0.7 0.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.0 16.2 0.0 0.0 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.5 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 7.1 3.9 7.5 7.9 6.3 10.9 4.3 9.2 5.8 0.0 1.1 0.0 5.5 7.2 0.0 0.0 17.8 6.7 2.3 43.6 0.0 0.1 189.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 25.4 0.0 0.0 0.0 0.6 1.2 1.1 0.0 0.0 1.7 0.0 0.0 11.3 0.1 0.0 0.4 1023.7 0.3 0.0 0.4 0.0 0.1 31.2 0.2 0.0 0.0 2.2 CERCAM "CEECAM1, CerCAM, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.1" "Cell type enhanced" "Detected in many" 8 "Extravillous trophoblasts: 48.9;Fibroblasts: 70.1;Melanocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD8 T-cell: 5.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 55.6;ASC TERT1: 59.3;fHDF/TERT166: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 12.7 5.1 40.0 7.2 65.5 1.6 9.0 10.0 62.1 19.1 6.9 61.2 5.0 4.8 11.4 10.9 8.2 6.0 17.3 8.8 72.8 34.7 4.9 1.8 5.3 2.3 59.5 28.1 14.1 18.8 15.8 21.6 27.4 31.4 11.1 5.2 3.5 13.2 13.6 4.3 8.9 6.0 27.7 78.1 3.3 5.4 5.2 62.1 0.0 6.7 2.4 2.7 15.1 6.6 0.3 2.0 0.3 1.6 1.1 5.3 2.2 9.5 6.1 6.9 7.3 55.6 59.3 5.9 30.9 29.2 8.1 6.1 2.2 0.4 0.0 12.7 50.4 6.9 6.5 3.0 4.1 3.1 2.4 4.9 0.5 5.6 3.3 17.0 1.1 17.3 32.8 2.2 8.8 2.1 33.5 9.1 0.6 2.8 7.6 10.5 18.1 0.4 11.7 0.4 0.4 4.7 0.9 4.8 1.3 3.8 3.6 1.0 1.9 6.9 8.4 3.5 2.3 6.8 2.3 10.1 21.6 5.9 29.6 4.7 8.9 6.9 0.1 20.4 3.4 4.2 0.3 1.1 0.1 3.8 1.6 0.3 0.3 0.3 4.7 1.5 0.1 0.1 5.3 0.3 1.1 0.1 2.0 0.0 2.2 40.0 65.5 10.0 24.5 72.8 34.7 59.5 28.1 31.4 62.1 6.0 13.0 0.0 6.2 7.9 1.1 3.2 0.0 6.7 21.6 10.4 0.0 14.3 0.0 10.7 2.0 7.1 0.0 0.0 2.9 48.9 70.1 3.9 8.1 0.0 5.9 6.4 0.0 18.4 0.6 1.5 22.5 4.7 38.8 1.0 0.0 0.1 6.9 0.0 24.8 0.5 0.7 6.5 15.6 1.0 19.0 3.6 16.4 2.5 0.0 2.0 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555594-17583162 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Extravillous trophoblasts: 66.0;Hofbauer cells: 81.3;Kupffer cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" No No Vesicles "HPA047821: AB_2680168" "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavorable (3.83e-4)" 29.8 11.4 12.1 26.9 16.5 21.3 36.2 15.6 13.1 18.2 18.5 10.8 9.6 12.0 21.9 20.2 17.6 19.2 18.1 21.7 10.8 7.1 11.1 17.8 25.1 46.1 19.4 7.3 19.0 15.2 7.9 8.1 29.6 11.8 12.6 11.6 9.5 12.0 13.0 10.7 16.7 17.3 25.7 11.3 30.9 13.9 11.2 17.9 10.3 11.3 12.7 11.9 19.6 19.1 2.5 11.5 7.6 17.4 1.4 3.6 7.1 23.2 27.5 13.4 18.4 53.2 33.0 21.4 21.8 12.8 28.8 29.9 20.8 36.7 11.9 39.1 38.2 24.6 20.8 13.6 25.3 17.5 6.7 21.8 11.4 35.8 19.7 29.2 27.2 34.9 27.3 22.7 32.2 13.5 11.7 32.3 7.6 23.3 6.0 10.4 10.2 13.7 17.6 9.9 16.9 26.9 14.7 17.1 18.2 6.1 15.5 9.7 7.0 23.4 18.7 22.1 9.1 9.7 39.7 22.5 57.2 16.2 50.7 35.4 10.8 27.3 13.1 33.8 51.9 25.9 1.1 15.0 7.6 3.4 17.4 2.0 2.3 3.2 3.2 11.5 2.5 2.3 3.6 2.4 1.4 12.6 4.4 1.9 7.1 12.1 16.5 15.6 13.1 10.8 7.1 19.4 7.3 11.8 17.9 17.9 30.0 6.0 4.6 17.3 3.6 8.9 5.1 5.3 18.2 10.4 5.9 5.4 0.0 11.4 2.7 14.6 9.7 0.0 6.9 66.0 26.7 5.5 8.1 12.3 81.3 12.7 5.2 9.2 58.8 2.3 17.5 43.3 16.9 8.2 13.7 1.7 10.2 5.8 20.5 4.1 2.9 12.9 17.3 3.1 13.9 18.2 7.0 10.2 15.3 7.5 COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.0" "Cell type enhanced" "Detected in some" 20 "Early spermatids: 38.2;Late spermatids: 52.3;Sertoli cells: 12.9" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "basophil: 8.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 8.1" "Cell line enhanced" "Detected in many" "Hep G2: 12.7;OE19: 10.2;SK-MEL-30: 13.7;U-251 MG: 13.1;WM-115: 16.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" 2.1 9.4 10.8 1.7 16.6 1.9 2.8 10.6 39.0 2.0 3.0 31.3 0.0 1.4 3.0 5.2 1.7 3.5 3.7 11.7 15.3 7.9 1.8 1.0 4.5 1.1 20.2 12.9 2.3 3.5 1.0 1.9 0.8 17.4 8.1 2.0 3.5 4.4 3.7 11.0 1.1 1.4 3.0 21.8 1.3 3.4 5.0 22.5 0.0 5.1 1.8 1.5 2.4 1.4 0.0 0.0 8.1 0.0 0.7 0.6 0.1 0.1 0.0 4.4 0.2 2.3 3.4 0.1 1.2 0.5 0.6 0.7 2.1 0.2 0.0 0.3 3.3 0.8 0.0 4.2 0.0 1.1 4.6 2.3 0.3 0.0 12.7 0.1 4.1 0.0 2.0 0.0 0.6 0.1 6.4 0.0 0.1 4.1 5.4 4.6 0.1 0.2 0.2 3.0 10.2 0.0 0.4 0.0 0.0 0.0 0.9 1.7 2.7 0.2 0.0 13.7 2.9 0.0 0.2 0.0 0.5 0.4 0.0 13.1 8.0 0.0 0.0 0.4 2.0 16.9 8.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 10.8 16.6 10.6 17.2 15.3 7.9 20.2 12.9 17.4 22.5 0.0 0.0 0.0 0.4 0.3 0.8 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 38.2 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.3 52.3 2.0 1.5 1.7 0.0 0.0 4.8 1.0 0.0 3.9 0.2 0.2 12.9 0.5 0.3 0.4 0.4 0.0 3.5 0.0 0.3 DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636360-133659344 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 86.6;brain: 36.2;liver: 35.6" "Cell type enriched" "Detected in single" 43 "Ito cells: 17.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 45 "pons and medulla: 36.2" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 2.0" "Lineage enriched" "Detected in single" 21 "T-cells: 2.0" "Cell line enriched" "Detected in single" 340 "SH-SY5Y: 206.1" "Region enriched" "Detected in some" 6 "pons and medulla: 23.2" "Region enriched" "Detected in single" 38 "pons and medulla: 25.1" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 2000000000 Vesicles "Endoplasmic reticulum" "HPA002130: AB_2666554, HPA005960: AB_1078628, HPA070789: AB_2686312" "unprognostic (1.93e-3)" "unprognostic (7.52e-3)" "unprognostic (8.53e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-3)" "unprognostic (3.38e-3)" "unprognostic (3.39e-3)" "unprognostic (3.97e-2)" "unprognostic (1.71e-1)" "unprognostic (8.99e-2)" "unprognostic (5.80e-2)" "unprognostic (7.69e-2)" "unprognostic (2.81e-7)" "unprognostic (9.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.49e-2)" "unprognostic (5.06e-3)" 0.7 86.6 0.1 0.3 0.1 0.0 0.0 0.1 0.8 0.3 0.0 1.9 0.7 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.5 35.6 0.3 0.6 0.0 0.0 0.1 1.3 0.0 0.6 0.4 36.2 0.8 0.0 1.0 0.2 5.9 0.0 0.0 0.2 0.0 1.4 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.2 206.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.1 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068972-12123225 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.5" "Group enriched" "Detected in many" 4 "Hepatocytes: 213.4;Proximal tubular cells: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA Mitochondria "HPA037949: AB_2675752, HPA037950: AB_10673650, HPA066098: AB_2685617" "unprognostic (3.76e-2)" "unprognostic (8.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.04e-3)" "unprognostic (3.83e-3)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.02e-3)" "unprognostic (3.46e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.43e-4)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.88e-3)" 5.7 6.3 6.5 4.7 6.6 2.2 5.0 5.7 7.2 5.5 5.7 9.8 5.0 4.5 4.7 5.0 5.1 4.2 4.5 7.7 5.3 4.8 23.8 69.5 4.2 6.9 7.5 5.2 7.1 16.6 5.4 4.1 4.7 6.2 7.6 6.3 7.2 9.7 7.1 10.5 3.6 4.3 3.5 6.1 5.1 6.1 4.4 6.6 10.1 6.8 6.7 8.0 5.2 4.1 9.5 12.5 16.8 11.0 10.2 4.1 3.3 11.4 8.8 13.2 10.5 8.2 4.9 16.0 5.8 3.7 10.4 9.2 5.6 6.9 8.3 1.9 3.6 4.8 16.3 13.8 4.5 11.9 4.6 6.2 4.5 3.5 4.3 8.1 1.8 1.7 6.0 3.5 6.0 2.4 4.1 5.6 10.1 7.0 6.7 2.8 22.2 6.0 3.2 7.3 10.6 2.1 10.3 4.3 7.0 6.7 2.7 3.4 15.5 11.4 20.4 6.8 14.8 45.0 6.5 2.5 3.4 2.5 7.0 4.2 6.0 4.2 5.3 4.3 3.2 5.6 16.8 4.8 10.7 3.2 6.8 3.4 9.5 2.5 2.1 8.6 7.8 2.5 3.3 14.0 10.2 11.0 12.5 4.1 3.3 6.5 6.6 5.7 7.2 5.3 4.8 7.5 5.2 6.2 6.6 11.9 32.1 21.6 5.5 4.6 11.5 26.6 25.5 5.3 6.8 15.7 9.8 22.3 16.6 9.3 2.6 7.4 10.3 0.0 9.7 18.5 6.6 11.2 8.1 213.4 8.4 25.4 10.9 11.6 11.9 3.1 11.5 11.3 5.0 13.6 19.6 10.8 9.7 10.5 11.3 55.4 18.7 12.9 5.0 5.6 3.6 5.3 11.3 7.1 15.0 6.2 DLD "DLDH, GCSL, LAD" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107890970-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Cardiomyocytes: 284.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 16000000 Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 25.7 37.9 14.5 12.7 25.4 12.0 15.2 16.6 27.2 13.2 28.0 10.6 12.2 20.9 13.6 9.6 25.6 11.6 12.7 69.1 16.4 14.4 40.7 37.9 11.0 13.0 16.7 20.1 15.1 14.8 24.6 22.4 15.4 29.3 14.7 26.8 12.8 19.4 14.4 71.5 13.8 29.5 23.7 10.6 17.4 23.0 10.6 10.7 18.7 17.0 31.8 16.9 20.1 11.7 13.5 30.4 45.8 37.8 22.9 19.4 20.2 40.1 32.6 18.1 31.1 26.0 23.0 20.5 23.1 19.5 26.9 20.9 38.0 22.6 39.3 39.9 24.5 44.0 26.7 36.3 32.6 40.7 26.2 21.6 27.6 43.2 27.1 20.0 45.4 28.5 26.2 23.7 28.6 15.6 17.1 32.3 33.0 68.9 29.3 29.2 45.1 37.1 32.9 21.5 48.5 23.7 26.8 29.0 53.3 36.8 60.0 22.5 23.8 37.8 64.0 34.0 37.6 24.4 38.9 20.4 29.8 24.4 57.9 35.1 22.2 42.3 26.4 28.0 48.5 30.7 36.5 22.3 45.8 17.5 28.2 18.5 13.5 17.7 17.3 30.4 12.3 18.7 19.4 14.0 22.9 37.8 10.5 16.8 20.2 14.5 25.4 16.6 27.2 16.4 14.4 16.7 20.1 29.3 10.7 26.8 16.5 23.1 30.6 27.8 45.9 284.8 61.1 37.5 18.2 75.0 21.6 94.8 192.3 59.5 3.8 30.0 47.9 46.7 49.3 49.9 26.3 23.6 26.5 77.8 61.0 20.6 29.4 27.6 36.8 5.6 21.6 34.1 35.4 65.9 39.3 31.3 37.7 56.1 39.6 134.4 33.4 25.8 43.4 41.2 52.4 28.2 90.6 27.7 64.6 28.5 DLST DLTS ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903745 "Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported Approved Nucleoplasm,Mitochondria NA NA 800000 "Nucleoplasm, Mitochondria" "HPA003010: AB_1078679" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "unprognostic (2.45e-3)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.13e-12)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (4.55e-3)" 32.2 38.6 12.0 22.7 19.9 28.5 31.3 19.1 25.6 31.2 36.0 18.5 15.9 24.7 26.3 28.3 31.4 19.2 29.7 47.6 10.8 11.8 43.7 45.1 20.8 26.7 13.5 13.7 21.5 27.1 25.8 16.2 25.2 19.7 20.9 26.8 19.2 22.3 20.1 59.2 26.9 43.2 32.9 11.4 20.8 24.3 21.0 10.4 23.5 27.2 49.8 28.4 26.9 21.1 3.8 6.3 8.4 4.3 7.7 5.3 3.2 25.8 27.0 20.7 14.6 32.5 36.9 31.7 33.8 34.4 34.6 32.4 26.5 28.1 26.3 14.4 38.8 15.6 29.2 34.8 33.4 36.6 19.0 14.6 21.5 22.6 23.2 33.6 15.2 14.8 37.7 29.3 33.5 41.4 31.2 35.6 11.9 16.4 17.9 37.5 34.7 18.0 21.6 17.7 45.7 25.4 23.1 30.4 14.5 42.9 31.8 24.6 20.9 31.9 42.6 22.0 19.3 39.0 22.0 31.5 21.1 27.6 25.7 23.1 12.7 13.2 23.1 30.8 15.8 22.0 8.4 3.0 5.0 5.0 4.3 4.5 3.8 4.5 3.9 4.7 2.7 4.0 5.3 3.0 7.7 3.9 6.3 4.4 3.2 12.0 19.9 19.1 25.6 10.8 11.8 13.5 13.7 19.7 10.4 6.0 4.5 20.7 19.3 23.5 17.5 23.4 20.4 2.7 3.4 19.2 29.5 33.7 48.0 32.5 6.2 14.6 39.3 0.0 22.3 30.6 23.8 21.8 20.7 37.3 28.4 12.7 14.3 24.5 16.2 3.4 16.7 16.5 21.9 36.1 28.3 8.5 35.0 25.9 19.4 51.5 20.0 25.8 17.9 9.3 11.7 24.8 66.5 20.3 36.1 20.8 DOT1L "DOT1, KIAA1814, KMT4" ENSG00000104885 "DOT1 like histone lysine methyltransferase" Q8TEK3 19 2164149-2232578 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 64.7" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011875, HPA071217, HPA074977" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "HPA011875: AB_2668552, HPA071217: AB_2686364, HPA074977: " "unprognostic (1.41e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.08e-1)" "prognostic favorable (6.00e-4)" "unprognostic (2.53e-3)" "unprognostic (2.21e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (5.25e-3)" "unprognostic (8.18e-3)" "unprognostic (2.56e-1)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" 7.3 8.8 7.0 10.7 11.7 20.1 5.1 20.6 11.7 4.5 7.9 9.8 6.0 13.5 6.4 4.9 8.3 5.4 6.9 5.7 7.0 3.6 9.5 8.5 10.0 8.4 11.9 5.3 6.5 10.8 3.6 8.3 11.6 7.1 5.7 4.9 9.5 6.1 7.4 9.8 9.9 13.0 4.2 6.7 10.4 13.3 64.7 9.7 10.5 9.2 7.0 9.1 4.8 5.3 0.7 1.0 3.0 0.9 2.8 1.4 0.6 12.2 6.6 22.4 12.2 1.7 2.5 29.5 7.0 1.5 3.8 3.1 8.4 4.6 14.4 3.4 4.5 3.3 11.0 7.4 3.9 1.8 7.3 9.3 13.2 10.8 8.2 2.7 18.9 24.4 2.4 2.9 7.4 3.8 3.1 3.1 8.2 16.0 15.1 3.0 7.0 15.1 20.9 17.3 7.8 11.8 15.6 6.3 9.9 2.1 5.8 15.0 11.6 4.9 14.6 9.2 6.2 6.7 14.5 4.4 10.7 9.8 15.8 13.4 14.0 18.3 10.0 10.6 13.1 6.2 0.5 0.7 3.0 0.9 0.3 1.4 0.7 0.8 0.2 0.9 0.7 0.5 0.3 0.3 2.8 0.9 1.0 0.1 0.6 7.0 11.7 20.6 11.7 7.0 3.6 11.9 5.3 7.1 9.7 29.8 18.9 9.9 9.3 15.8 25.0 5.2 20.4 6.7 6.8 8.7 62.8 5.3 3.3 10.1 25.8 7.1 25.4 0.0 10.4 11.3 11.0 12.4 5.8 13.1 9.3 12.7 20.0 6.7 11.9 11.9 2.8 14.6 11.8 5.4 10.8 7.3 14.1 14.0 3.2 2.2 26.6 0.0 8.1 28.3 23.5 17.3 13.6 4.9 11.7 14.2 EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618963-137870016 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060022, HPA074729" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Nucleoplasm, Nuclear bodies" "HPA060022: AB_2684190, HPA074729: " "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.03e-1)" "prognostic favorable (8.91e-4)" "unprognostic (5.87e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.26e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-2)" "unprognostic (6.58e-3)" "unprognostic (4.24e-1)" "unprognostic (7.12e-3)" "unprognostic (7.75e-2)" 16.6 18.3 16.4 23.2 22.3 24.9 17.1 23.7 20.4 16.3 20.7 21.6 20.4 17.1 22.0 13.0 17.9 18.5 20.0 12.1 12.8 9.6 12.7 14.9 14.9 25.0 27.8 12.1 21.4 13.6 15.1 16.2 17.9 18.6 16.9 12.4 19.1 16.5 18.0 23.1 17.3 17.9 21.5 12.5 22.1 16.4 30.8 21.5 22.3 18.9 11.0 22.2 19.2 15.7 20.0 19.0 25.0 13.7 13.1 15.6 6.9 11.1 22.4 25.1 23.3 10.7 11.1 21.1 14.8 9.4 10.8 8.9 14.6 14.0 34.3 14.4 11.2 13.1 24.1 15.0 16.2 8.6 19.2 10.6 14.5 22.4 9.3 9.3 22.0 17.4 9.9 11.4 13.1 12.8 8.0 17.8 13.0 21.7 11.9 7.7 25.8 25.8 10.9 24.5 17.7 14.9 33.2 21.6 19.8 9.1 20.6 22.3 18.1 28.1 19.8 6.4 18.8 22.2 17.8 16.7 12.8 13.3 19.6 14.0 7.6 21.1 28.3 9.5 11.8 13.8 13.6 13.7 16.3 15.6 11.7 10.0 13.3 13.5 13.3 10.4 20.0 13.3 11.8 25.0 13.1 12.0 19.0 11.1 6.9 16.4 22.3 23.7 20.4 12.8 9.6 27.8 12.1 18.6 21.5 17.9 16.3 36.9 20.3 15.5 38.3 24.3 17.8 21.4 22.7 21.0 49.1 18.6 3.3 20.9 68.8 24.8 19.8 0.0 18.3 18.0 18.4 25.8 17.4 28.8 17.0 47.7 27.0 17.8 23.4 119.3 33.1 16.5 11.8 23.4 20.2 23.1 20.1 25.9 35.3 11.9 48.0 12.9 15.3 58.1 54.9 17.7 22.2 23.3 20.5 22.0 EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897687 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 10.3;NTERA-2: 15.8;U-266/84: 12.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" NA NA "Nuclear speckles" Nucleoplasm "HPA050550: AB_2681170, HPA060259: AB_2684234" "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" 9.4 12.2 13.1 9.6 21.4 7.6 6.3 17.1 17.5 8.0 7.7 12.3 8.4 14.6 15.0 11.7 18.0 7.6 8.1 7.6 12.3 12.4 5.3 4.4 8.5 6.9 12.6 10.6 10.6 13.2 2.2 8.1 6.0 10.3 10.4 4.3 7.2 5.6 9.6 5.2 5.5 10.1 9.6 8.4 9.1 9.8 7.6 14.9 14.6 9.5 4.8 7.2 8.7 7.6 0.3 0.6 0.0 0.7 0.1 1.1 1.3 0.0 3.6 6.4 0.0 2.8 1.5 4.1 2.8 2.3 3.2 2.6 0.0 0.0 0.0 6.3 4.5 3.3 0.0 0.0 6.9 1.5 4.2 9.6 0.0 0.0 0.0 0.0 10.3 0.0 3.9 1.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 7.3 0.0 15.8 0.0 0.0 6.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.8 5.3 2.7 0.0 0.0 3.0 3.4 2.6 5.7 0.0 9.1 12.4 3.0 3.9 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.2 0.1 0.8 0.6 0.3 0.3 1.1 1.1 0.0 0.1 0.7 0.6 0.2 1.3 13.1 21.4 17.1 16.5 12.3 12.4 12.6 10.6 10.3 14.9 14.9 11.8 22.3 5.6 7.4 59.2 4.5 22.9 9.4 19.4 24.4 39.3 19.7 6.6 12.9 33.8 11.9 8.9 0.0 10.6 12.5 13.2 5.8 13.9 6.4 14.1 36.5 21.7 20.3 9.1 44.9 25.3 9.9 18.6 16.2 15.5 28.2 11.0 5.8 21.5 7.8 48.2 25.8 8.5 6.1 30.6 9.7 4.7 14.9 15.0 2.6 EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "Rod photoreceptor cells: 268.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA005478: AB_1848340, HPA077684: AB_2732356" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (2.19e-2)" "unprognostic (8.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-3)" "unprognostic (1.76e-2)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-3)" "unprognostic (5.22e-3)" "unprognostic (4.11e-3)" "unprognostic (1.48e-2)" "unprognostic (4.60e-2)" "unprognostic (3.29e-1)" "unprognostic (5.39e-2)" "unprognostic (4.74e-2)" 21.7 10.4 15.0 10.1 25.0 9.9 18.7 39.6 26.1 18.4 15.1 21.4 10.0 9.7 29.8 21.2 10.6 18.8 9.7 17.2 19.0 11.2 13.6 5.3 12.6 14.0 13.7 22.0 38.2 8.1 20.0 19.1 9.3 25.6 13.1 12.1 21.5 10.7 19.3 25.4 16.0 14.0 16.4 19.9 16.0 10.6 8.6 16.7 11.9 15.0 7.5 14.9 16.0 15.9 6.2 6.0 18.8 5.4 4.8 8.3 2.3 5.5 5.8 8.0 5.5 32.1 19.4 6.8 8.9 8.2 7.4 7.6 2.7 6.9 8.4 5.6 9.4 7.3 12.6 5.2 5.9 10.7 9.3 9.3 2.9 10.8 3.3 11.0 6.2 7.0 11.1 10.8 5.6 13.6 13.0 6.0 8.5 7.6 11.9 6.5 2.3 10.1 8.0 2.2 5.1 3.0 6.6 8.2 8.9 7.7 5.9 5.5 4.4 4.9 2.4 5.9 11.9 8.5 4.0 6.2 8.0 3.3 9.3 5.6 12.5 6.3 5.0 5.7 6.5 4.0 10.2 5.2 6.9 5.9 5.4 8.3 5.7 5.2 6.0 1.9 6.2 7.7 5.7 18.8 4.8 3.3 6.0 5.7 2.3 15.0 25.0 39.6 26.1 19.0 11.2 13.7 22.0 25.6 16.7 8.9 17.3 10.7 12.1 4.6 67.2 34.7 17.8 38.8 17.0 12.2 62.8 6.1 8.3 9.2 0.4 12.2 6.7 46.7 6.4 2.6 7.5 7.2 19.7 6.7 7.7 44.5 12.5 15.4 11.6 1.1 28.7 10.6 1.7 20.8 4.2 32.0 9.4 6.0 32.2 8.1 268.1 51.8 13.3 9.3 8.8 5.4 9.0 15.9 6.8 7.6 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.5;lymphoid tissue: 44.1" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 72.2;Spermatocytes: 126.7;Spermatogonia: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009589 Enhanced Supported Nucleoplasm NA NA Nucleoplasm "CAB009589: " "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavorable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavorable (8.18e-12)" "prognostic favorable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 2.0 1.7 1.8 10.6 1.6 25.5 1.4 4.9 2.7 2.6 4.8 1.1 0.1 3.8 1.7 2.8 11.0 0.9 3.0 0.9 0.8 0.6 1.7 3.3 2.3 12.6 1.3 0.3 2.2 3.8 0.6 1.7 3.4 1.4 1.4 5.1 1.8 3.2 1.6 3.7 6.4 4.8 1.5 1.2 5.8 2.7 19.6 1.3 44.1 0.9 5.5 12.4 2.6 3.5 1.5 4.7 1.3 3.9 8.5 10.3 1.7 17.0 8.0 27.3 18.2 0.8 1.4 14.9 13.3 5.4 11.0 11.1 12.0 19.7 30.2 6.5 5.0 10.0 10.5 14.0 4.6 14.0 43.2 14.0 12.9 9.9 9.3 2.2 28.6 10.6 1.2 2.6 8.2 4.4 3.3 6.4 29.3 27.3 20.1 9.8 19.3 55.6 23.9 21.7 15.0 10.8 34.4 15.3 18.7 5.1 8.2 26.1 16.6 16.7 12.7 4.4 7.3 9.3 12.3 3.9 11.7 5.4 23.3 23.8 18.0 19.6 30.4 10.7 19.6 22.9 0.5 2.2 1.3 1.7 1.5 1.3 1.5 3.4 2.9 4.7 0.8 1.9 1.2 0.2 8.5 3.9 1.0 10.3 1.7 1.8 1.6 4.9 2.7 0.8 0.6 1.3 0.3 1.4 1.3 0.0 7.9 6.7 5.7 23.6 4.8 6.5 2.5 14.7 7.9 7.0 33.4 13.6 3.3 9.1 72.2 7.1 6.7 23.3 7.4 29.5 10.8 4.4 21.8 1.3 10.4 14.3 8.6 4.3 8.9 19.2 2.8 10.9 13.5 19.0 10.2 2.0 10.1 9.3 0.7 1.0 21.1 6.5 9.9 126.7 62.4 25.3 25.5 18.7 18.6 4.0 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: AB_2679141" "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 14.4 11.3 17.7 17.0 19.2 28.6 16.8 43.8 21.2 17.3 14.6 19.8 18.1 8.5 21.8 17.1 10.6 15.7 14.1 10.2 17.3 13.4 13.1 9.3 15.3 19.6 16.6 18.7 35.6 16.8 28.9 21.8 10.2 15.4 15.6 12.4 14.4 14.2 19.2 11.1 16.8 14.2 15.2 12.1 15.7 12.3 7.9 23.4 16.6 16.6 7.8 19.4 18.8 24.6 6.7 3.5 8.3 2.0 6.5 5.3 0.8 12.1 5.6 15.2 11.4 9.3 11.1 4.5 5.5 8.0 5.8 6.7 11.3 8.8 15.0 11.3 8.0 10.3 10.6 16.1 6.1 11.6 16.5 6.2 29.4 5.2 6.1 5.2 17.5 5.7 5.3 6.2 12.7 17.0 7.3 9.0 9.8 19.1 12.8 7.3 9.5 11.6 10.3 9.2 5.0 8.4 8.8 14.6 5.0 8.5 9.2 12.5 8.1 13.8 4.5 2.9 8.3 7.8 5.9 13.2 9.9 9.0 7.2 9.8 3.7 2.9 10.1 3.7 12.9 5.9 8.3 2.0 4.6 5.3 1.3 4.3 6.2 4.8 4.6 0.8 6.7 4.9 4.8 1.3 6.5 1.4 3.5 3.9 0.8 17.7 19.2 43.8 21.2 17.3 13.4 16.6 18.7 15.4 23.4 65.5 59.8 31.5 64.8 77.2 147.8 34.4 38.2 53.5 35.2 36.6 143.3 12.2 3.3 26.8 6.6 70.1 19.7 0.0 22.3 8.1 43.5 71.4 26.7 23.1 14.2 184.3 63.8 45.4 32.6 4.7 61.9 26.1 40.5 33.3 29.3 117.0 23.2 14.4 73.9 6.9 144.6 64.7 59.7 11.1 14.9 70.4 5.0 50.7 27.3 49.9 KMT2B "CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7" ENSG00000272333 "Lysine methyltransferase 2B" Q9UMN6 19 35718019-35738878 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 61.2;Rod photoreceptor cells: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006487 Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA006487: AB_1080587" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.41e-2)" "unprognostic (7.95e-2)" "unprognostic (9.92e-2)" "unprognostic (3.53e-3)" "unprognostic (2.33e-2)" "unprognostic (4.57e-2)" "unprognostic (7.28e-2)" "unprognostic (2.07e-2)" "unprognostic (3.13e-3)" "unprognostic (2.63e-3)" "unprognostic (9.47e-3)" "unprognostic (2.10e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" 10.2 9.3 11.4 14.2 13.1 18.4 10.4 23.9 11.4 10.0 12.0 14.2 12.9 13.8 13.0 7.1 11.4 11.6 12.6 7.5 11.0 5.3 9.9 8.9 10.6 14.7 14.7 6.8 15.3 19.6 10.8 13.3 9.3 11.2 12.1 5.6 13.8 14.7 10.0 13.3 19.9 12.3 12.2 12.4 15.8 12.1 21.5 14.9 14.1 14.9 7.0 14.2 12.4 14.2 0.4 0.7 3.2 0.7 2.1 0.7 0.2 11.5 19.5 9.0 9.9 4.7 4.6 9.4 5.6 4.1 5.7 4.4 13.0 5.9 10.3 8.8 4.6 6.1 7.6 8.1 4.8 2.5 15.2 9.0 18.5 9.1 6.5 4.6 11.2 21.2 6.2 6.5 5.8 6.4 5.1 5.5 10.7 15.4 12.9 3.7 11.8 9.5 9.7 8.3 10.0 6.9 15.0 5.9 5.6 3.1 10.3 10.2 8.2 8.5 13.8 5.9 5.0 8.4 12.0 7.7 11.4 12.4 7.6 11.8 17.8 10.9 8.2 6.2 10.4 7.9 1.0 0.7 0.6 0.7 0.4 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.4 3.2 2.1 0.3 0.7 0.2 0.2 11.4 13.1 23.9 11.4 11.0 5.3 14.7 6.8 11.2 14.9 8.9 19.1 13.3 8.5 11.3 61.2 7.7 10.2 4.0 5.7 8.7 49.1 5.2 0.0 5.5 2.1 11.7 14.0 0.0 6.7 4.9 8.1 13.1 4.7 9.7 7.3 33.4 19.4 11.6 8.7 4.1 7.5 6.4 5.0 6.4 10.4 27.2 7.1 11.4 11.7 4.2 74.2 0.0 8.2 28.1 36.4 11.3 7.9 10.2 11.3 12.8 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436005 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm NA NA Nucleoplasm "HPA074736: AB_2686709" "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 13.9 12.6 11.7 16.7 18.6 29.7 14.5 24.8 14.1 18.4 12.6 15.5 21.4 9.7 20.2 20.6 14.4 12.8 12.7 10.8 13.4 9.5 10.3 11.4 13.0 12.1 17.7 9.4 18.8 18.4 18.8 18.9 38.0 12.6 14.0 11.8 12.6 15.8 22.9 30.3 25.2 13.1 13.6 16.0 14.6 14.9 13.6 19.6 22.6 16.9 9.3 16.8 17.8 31.6 5.6 3.5 16.1 3.9 5.5 2.9 0.6 9.7 4.9 9.1 9.7 16.5 10.0 10.7 5.1 3.9 4.1 5.0 9.3 5.9 15.5 7.4 9.2 5.6 5.6 9.8 7.4 6.9 9.8 5.0 9.2 7.4 6.4 8.0 15.5 11.3 8.4 10.3 5.8 7.8 6.6 5.8 8.1 14.8 13.4 8.9 13.6 11.2 14.1 5.5 7.6 4.9 7.6 8.3 8.1 7.0 10.0 13.3 10.5 8.4 15.0 5.5 9.9 4.9 12.8 7.3 6.8 3.6 7.3 7.2 14.1 6.9 16.7 8.9 12.8 7.0 8.8 3.5 4.3 2.1 2.2 2.9 5.6 1.7 1.7 1.7 3.8 2.7 1.8 16.1 5.5 3.9 3.5 1.3 0.6 11.7 18.6 24.8 14.1 13.4 9.5 17.7 9.4 12.6 19.6 71.5 66.6 54.7 36.1 79.1 82.8 58.2 45.9 44.2 92.1 43.6 163.0 29.7 5.0 30.2 18.6 49.2 41.0 23.3 28.7 45.7 47.0 48.1 62.5 36.6 29.6 76.3 65.1 41.7 48.8 11.0 62.5 61.0 40.5 25.2 44.5 62.2 33.0 43.8 56.6 15.7 75.2 25.8 50.1 33.5 31.5 84.2 106.4 50.4 30.3 55.0 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018975-49059774 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Plasma membrane, Cytosol" Nucleoplasm "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 12.1 7.6 4.9 6.7 10.8 26.1 6.8 11.7 10.5 9.5 6.5 5.8 13.0 5.5 15.7 7.4 8.8 8.9 5.8 9.1 6.1 3.5 6.2 6.5 22.9 9.6 6.7 3.3 9.7 11.6 13.3 9.2 12.9 13.7 6.7 6.6 9.8 7.6 8.0 16.1 13.6 9.4 7.1 9.1 13.6 8.3 7.3 5.7 6.2 11.0 6.1 7.6 7.0 6.3 2.0 2.2 5.9 0.5 1.5 0.8 0.6 17.1 16.3 16.5 13.3 17.1 11.5 17.7 9.1 9.5 11.8 6.3 28.6 7.3 17.8 11.8 12.7 8.5 11.6 21.7 10.0 9.8 10.4 17.4 22.6 17.1 15.3 11.7 26.8 22.7 9.7 14.4 16.5 17.1 14.1 17.5 18.5 28.3 9.9 13.3 18.9 13.3 25.0 15.6 23.7 14.1 20.0 10.2 6.4 9.9 19.0 13.8 11.7 14.0 13.8 9.5 15.0 13.7 23.5 23.3 9.3 16.6 8.1 15.2 14.1 9.1 17.3 10.7 13.9 6.9 0.6 0.5 3.0 0.8 0.2 0.4 0.3 0.3 0.5 0.3 2.0 0.3 0.8 5.9 1.5 0.1 2.2 0.0 0.6 4.9 10.8 11.7 10.5 6.1 3.5 6.7 3.3 13.7 5.7 8.9 18.4 11.1 6.5 12.5 25.2 4.7 12.7 5.3 9.1 17.4 49.1 6.6 1.7 5.8 2.5 12.6 11.1 0.0 5.2 4.6 8.5 8.3 8.1 12.3 8.3 20.6 12.6 17.2 19.7 1.1 8.9 9.6 10.1 4.6 10.5 5.2 7.2 8.6 10.3 4.3 38.9 6.5 3.3 3.7 3.2 15.4 9.5 10.4 10.1 8.4 KMT2E "HDCMC04P, MLL5" ENSG00000005483 "Lysine methyltransferase 2E" Q8IZD2 7 105014179-105114361 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" "Chromatin regulator" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042866, HPA056125" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA042866: , HPA056125: AB_2683044" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (6.49e-2)" "unprognostic (4.34e-1)" "unprognostic (1.94e-1)" "unprognostic (4.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.98e-3)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (3.53e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.80e-5)" "unprognostic (1.68e-1)" "unprognostic (1.53e-1)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" 22.7 11.8 18.6 24.5 23.5 44.8 20.9 41.6 22.4 26.4 20.9 18.6 21.7 14.7 25.3 15.8 16.5 18.6 18.2 16.8 20.6 15.1 14.2 11.6 22.8 20.1 22.7 17.4 33.5 15.6 20.5 20.1 18.7 18.6 21.2 20.5 17.6 19.6 19.2 21.3 25.7 18.5 26.2 23.1 21.6 17.9 12.9 27.2 24.6 21.7 15.1 22.7 26.6 21.4 38.2 24.7 72.9 20.8 20.3 30.6 14.7 15.1 10.7 22.7 19.5 14.1 16.9 5.8 11.6 17.4 9.8 12.1 8.7 13.9 12.6 11.6 13.6 13.2 11.8 12.5 11.5 16.3 20.3 7.2 12.7 14.0 7.4 13.3 17.0 16.0 11.8 10.8 13.6 14.6 17.9 17.7 14.1 17.3 36.1 13.8 11.9 27.1 14.6 7.9 8.3 8.6 23.4 14.0 14.6 9.7 15.4 13.0 15.7 16.1 13.9 8.8 15.9 6.0 10.2 21.8 23.2 16.2 26.5 11.5 27.6 21.8 29.1 15.2 13.0 15.9 48.5 18.0 39.4 30.6 13.6 30.3 35.6 28.4 26.1 12.8 38.2 28.0 26.0 72.9 20.3 20.8 24.7 23.6 14.7 18.6 23.5 41.6 22.4 20.6 15.1 22.7 17.4 18.6 27.2 131.0 136.3 133.9 100.8 130.3 219.2 86.5 76.5 84.3 142.1 109.9 237.6 33.5 29.9 70.0 19.2 197.7 91.8 93.5 59.6 38.6 151.9 115.7 236.2 33.7 53.7 174.8 96.0 86.5 76.0 18.6 130.6 138.7 133.3 110.0 88.5 114.4 63.9 84.2 123.8 28.6 269.1 122.9 222.6 98.9 71.7 117.7 54.6 186.4 107.4 119.5 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409358 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes Nucleoplasm Cytosol "HPA064495: AB_2685273" "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 7.6 5.4 8.9 14.0 7.5 20.2 7.9 9.8 14.1 13.9 9.1 9.9 21.4 7.3 15.7 9.5 22.3 12.3 8.3 10.9 8.1 5.5 6.7 7.4 8.7 8.4 7.8 10.6 7.2 13.1 6.8 7.4 9.9 12.8 18.6 9.1 7.9 19.3 12.5 13.6 15.6 9.1 11.0 10.3 13.3 9.0 5.2 8.6 42.2 17.2 8.9 19.7 12.3 14.2 3.5 3.8 7.8 3.8 4.1 5.4 0.6 12.4 7.9 9.5 14.6 6.1 10.9 13.0 18.6 8.9 10.8 9.5 9.0 7.3 28.7 10.8 12.3 4.0 11.6 13.6 6.8 11.6 12.1 14.1 24.1 8.3 4.5 9.1 18.7 6.1 4.6 8.6 11.7 10.9 10.4 8.8 12.3 43.6 13.4 8.8 9.0 18.9 27.9 4.4 11.3 9.0 22.5 8.1 7.8 7.5 15.2 13.0 10.2 18.5 9.4 8.5 8.8 13.1 23.9 11.2 12.2 8.9 14.5 13.3 7.5 7.8 26.3 8.4 9.8 10.2 4.1 2.5 7.8 2.8 3.8 5.4 3.5 3.3 4.3 2.0 2.3 1.8 2.3 3.4 4.1 3.6 3.8 2.7 0.6 8.9 7.5 9.8 14.1 8.1 5.5 7.8 10.6 12.8 8.6 11.9 12.6 0.0 14.2 0.0 19.6 0.0 5.1 21.4 12.5 26.2 5.9 10.7 6.6 8.0 7.4 11.3 8.5 0.0 8.1 13.9 8.7 20.1 2.3 13.4 15.1 3.2 4.7 28.8 17.1 2.1 15.0 10.3 0.0 1.0 28.5 22.4 11.3 10.5 40.3 8.3 16.8 6.5 0.0 8.9 11.7 0.0 11.9 8.2 12.4 19.3 KMT5B "CGI-85, SUV420H1" ENSG00000110066 "Lysine methyltransferase 5B" Q4FZB7 11 68154863-68213828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063648 Supported Nucleoplasm NA NA Nucleoplasm "HPA063648: AB_2685073" "unprognostic (5.82e-2)" "unprognostic (4.25e-2)" "unprognostic (2.54e-1)" "unprognostic (5.36e-3)" "unprognostic (3.52e-1)" "unprognostic (2.94e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "unprognostic (5.54e-2)" "unprognostic (1.21e-1)" "unprognostic (3.79e-3)" "unprognostic (2.62e-1)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "prognostic favorable (9.30e-4)" 17.6 19.1 20.9 23.4 22.5 23.7 27.3 38.8 26.7 22.4 21.2 19.9 32.3 21.8 26.2 22.7 19.7 20.4 18.2 15.1 23.8 15.3 19.1 21.5 17.4 16.9 18.6 22.2 27.4 24.0 27.4 28.1 26.6 17.0 24.9 21.5 15.4 25.2 30.4 18.8 20.8 24.0 23.4 18.4 19.6 19.7 19.1 23.6 38.0 30.9 17.5 19.1 20.5 22.5 4.5 5.5 16.0 5.2 8.9 5.9 2.7 10.3 7.8 16.0 10.3 3.7 9.4 17.3 7.5 5.2 9.3 5.5 24.6 16.6 8.5 13.0 10.1 9.2 5.4 11.0 8.6 13.6 9.5 6.4 8.0 9.2 10.1 13.6 11.2 11.0 9.3 17.8 11.2 11.8 8.6 9.2 8.5 11.8 9.9 7.9 21.3 7.9 11.8 17.1 20.7 5.9 13.1 12.5 22.6 6.9 10.0 14.0 16.7 11.5 11.6 52.3 9.1 14.9 7.4 9.6 12.6 16.8 9.6 7.5 12.7 5.5 17.9 7.9 7.1 13.4 7.8 3.7 16.0 4.7 5.2 3.3 3.4 5.1 5.7 3.6 4.5 5.9 5.2 11.3 8.9 4.8 5.5 4.0 2.7 20.9 22.5 38.8 26.7 23.8 15.3 18.6 22.2 17.0 23.6 56.6 48.3 13.8 31.8 0.0 45.8 0.0 22.9 58.9 46.6 24.4 11.8 24.2 18.3 24.2 13.7 24.8 22.7 0.0 28.3 24.3 18.6 34.9 20.9 32.7 15.6 60.4 24.6 25.2 31.0 17.2 25.9 18.9 0.0 34.3 38.9 26.9 30.1 24.6 29.7 19.2 39.1 32.3 0.0 34.9 59.5 0.0 43.3 17.5 31.2 40.1 KMT5C "MGC2705, SUV420H2" ENSG00000133247 "Lysine methyltransferase 5C" Q86Y97 19 55339853-55348120 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 47.4;Cone photoreceptor cells: 47.1;Horizontal cells: 63.5;Rod photoreceptor cells: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEK 293: 16.6;SCLC-21H: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052294 Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA052294: AB_2681788" "unprognostic (4.02e-2)" "unprognostic (3.45e-2)" "unprognostic (2.92e-3)" "unprognostic (6.77e-3)" "unprognostic (2.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (8.69e-2)" "unprognostic (3.04e-1)" "unprognostic (9.48e-3)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.05e-8)" "unprognostic (7.39e-2)" "unprognostic (2.96e-1)" "unprognostic (9.41e-2)" "unprognostic (2.39e-2)" 5.0 5.6 8.5 7.3 15.7 13.4 5.4 20.0 10.7 5.1 7.5 11.2 4.9 11.9 7.0 5.4 4.6 11.0 7.4 4.2 11.2 4.5 5.1 4.4 5.5 4.6 17.1 5.3 6.1 8.5 6.2 11.7 6.5 9.6 6.6 3.8 6.3 7.7 6.3 6.6 13.5 8.5 3.6 6.2 6.2 9.8 7.0 14.7 10.1 5.1 2.3 3.5 6.3 4.6 0.3 0.8 0.9 0.6 1.1 0.8 0.3 5.0 3.5 3.3 2.8 0.7 0.9 9.3 1.4 0.6 0.5 1.3 2.2 4.3 5.0 1.8 1.1 0.2 2.8 2.1 1.8 0.6 4.5 16.6 4.0 2.5 2.2 1.2 2.3 4.8 0.8 2.5 1.7 0.9 0.7 1.1 5.5 9.8 2.8 0.6 5.8 6.6 5.2 6.0 3.0 5.2 9.8 3.9 4.9 0.8 1.3 16.2 6.9 0.7 3.7 2.0 1.9 4.2 2.9 1.2 1.6 4.0 0.5 1.0 8.3 4.1 3.2 0.8 5.6 2.2 0.3 0.6 0.3 0.7 0.4 0.0 0.1 0.5 0.7 0.6 0.3 0.3 0.8 0.9 1.1 0.0 0.8 0.2 0.3 8.5 15.7 20.0 10.7 11.2 4.5 17.1 5.3 9.6 14.7 6.0 5.5 1.9 11.9 0.0 47.4 0.0 10.2 6.7 5.7 3.5 47.1 25.7 1.7 5.8 1.6 2.2 8.4 23.3 2.6 16.4 3.1 9.2 2.3 1.0 8.3 63.5 7.0 4.9 3.1 1.5 6.9 4.9 0.0 1.0 14.9 28.9 6.1 15.3 6.0 2.1 46.0 6.5 0.0 8.4 11.1 0.0 16.6 9.6 13.3 9.8 MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401545 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 57.2;smooth muscle: 41.1" "Cell type enhanced" "Detected in some" 15 "Basal keratinocytes: 24.8;Early spermatids: 36.8;Muller glia cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 47 "memory B-cell: 4.9;naive B-cell: 2.8;plasmacytoid DC: 7.8" "Group enriched" "Detected in many" 58 "B-cells: 4.9;dendritic cells: 7.8" "Cell line enhanced" "Detected in many" "ASC diff: 38.5;ASC TERT1: 31.0;BJ: 23.4;fHDF/TERT166: 43.5;HBF TERT88: 28.1;U-2197: 69.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA035740 Approved Approved Cytosol NA NA Cytosol "HPA035740: AB_10610141" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (8.05e-2)" "unprognostic (9.87e-3)" "unprognostic (5.62e-2)" "prognostic favorable (7.09e-5)" "unprognostic (5.77e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.92e-2)" "unprognostic (6.24e-2)" "unprognostic (1.73e-2)" 1.9 19.5 13.4 3.8 12.5 0.2 1.4 0.3 16.0 17.2 7.7 6.7 7.3 2.7 57.2 7.8 17.4 1.9 15.1 3.2 9.8 1.1 21.4 1.2 15.3 2.9 1.0 6.4 2.4 1.7 0.1 4.3 3.3 0.2 17.6 4.9 0.9 10.6 21.5 0.4 7.4 4.5 41.1 0.8 3.2 3.1 3.1 4.6 0.8 1.5 7.7 7.7 9.4 8.6 4.9 7.8 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.9 0.0 38.5 31.0 0.0 23.4 15.9 8.6 15.1 0.0 0.2 0.1 0.0 43.5 7.1 0.0 0.3 0.1 28.1 0.0 4.3 0.0 0.0 0.0 0.3 0.0 0.0 7.3 0.0 17.3 0.5 10.7 0.0 0.0 0.0 1.7 5.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.1 0.0 10.5 0.0 0.6 0.0 0.0 0.1 0.5 2.3 0.0 1.3 0.1 3.9 3.7 69.7 12.2 0.9 0.0 0.0 10.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 4.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.3 13.4 12.5 0.3 16.0 9.8 1.1 1.0 6.4 0.2 4.6 0.0 2.2 3.4 0.4 24.8 0.2 0.6 0.0 0.0 4.5 1.8 0.0 0.6 0.0 0.4 36.8 0.0 0.0 0.0 0.0 1.0 9.6 0.2 3.5 0.0 0.4 0.0 0.0 0.0 0.0 6.8 0.3 0.6 6.8 0.0 0.0 14.0 0.4 0.0 0.4 0.0 0.8 0.0 0.4 0.5 0.4 5.9 0.0 0.0 0.0 0.0 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300215 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 11.8 13.2 11.9 25.4 15.7 23.9 14.0 28.9 16.7 15.6 14.2 18.5 17.0 10.6 19.0 13.9 17.8 13.6 15.8 11.7 12.8 11.5 14.4 10.5 12.3 19.4 12.9 11.7 16.6 27.1 24.6 19.3 16.0 13.4 14.2 14.3 13.8 13.5 18.7 20.6 16.1 14.5 15.6 13.2 16.1 13.1 28.1 16.1 27.3 20.1 10.6 22.7 13.4 20.2 10.2 8.9 18.7 10.8 10.9 7.8 2.9 9.9 12.8 13.3 11.5 6.6 8.5 0.4 9.0 9.0 12.7 11.8 2.8 8.3 20.5 10.2 12.4 11.7 8.5 21.2 20.0 15.4 34.7 12.8 9.1 14.5 0.1 10.9 19.6 10.8 8.0 12.1 15.0 14.1 9.0 18.4 13.0 12.4 7.2 12.7 20.8 13.6 6.3 14.5 6.7 11.3 15.1 1.7 6.3 8.2 12.1 16.3 11.2 23.4 10.2 7.0 12.9 10.2 16.3 13.5 8.8 12.9 5.6 11.1 8.5 7.4 14.7 5.1 9.6 9.4 10.7 9.1 9.4 7.5 6.1 6.3 8.5 6.3 5.0 6.7 10.2 7.8 6.3 18.7 10.9 10.8 8.9 5.7 2.9 11.9 15.7 28.9 16.7 12.8 11.5 12.9 11.7 13.4 16.1 20.8 26.1 42.4 26.2 15.0 91.7 37.5 33.1 13.4 36.4 52.4 141.4 34.8 14.9 22.8 25.5 31.5 21.9 0.0 18.5 20.4 23.3 24.0 39.4 16.3 24.2 84.2 40.3 31.3 29.2 33.9 47.2 39.1 15.1 50.5 19.4 35.7 20.1 24.6 31.1 13.9 100.0 51.8 19.6 63.2 47.7 18.1 29.6 51.1 21.5 23.5 NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871424-1982207 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 1: 11.9;Alveolar cells type 2: 17.3;Ciliated cells: 13.4;Club cells: 14.8;Collecting duct cells: 12.2;Hofbauer cells: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm No No Nucleoplasm "CAB068246: AB_2665690, CAB068247: AB_2665689, HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavorable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" 8.7 7.6 17.6 11.5 16.2 35.1 8.5 20.6 18.2 7.0 14.8 12.4 6.3 14.0 9.5 7.4 12.7 6.8 6.9 11.9 15.1 10.9 8.4 7.5 11.1 18.8 14.7 16.1 7.0 11.7 10.7 11.8 9.8 14.6 8.7 17.7 9.4 10.2 7.4 11.8 12.1 14.6 10.5 15.3 13.5 11.0 26.3 13.4 46.7 13.8 5.5 17.7 8.6 9.4 4.9 3.9 4.1 1.8 2.7 4.3 0.6 27.7 14.0 42.3 18.5 4.6 6.8 12.3 22.4 19.9 27.5 30.8 12.4 33.0 29.9 7.7 18.5 36.0 12.1 27.3 18.5 47.3 14.3 11.3 35.6 19.4 7.3 5.8 21.8 18.7 2.6 4.7 24.1 23.2 15.2 21.6 30.2 19.3 31.4 22.5 10.9 58.1 22.9 17.8 14.1 16.2 33.2 27.6 10.3 11.3 13.2 26.3 21.0 18.4 6.9 8.4 19.2 16.3 14.6 16.7 27.5 20.5 17.4 45.1 14.7 15.5 27.1 16.5 21.6 25.5 2.1 1.7 1.7 2.9 1.8 3.2 1.8 3.2 3.2 1.5 4.9 2.8 2.3 4.1 2.7 1.4 3.9 4.3 0.6 17.6 16.2 20.6 18.2 15.1 10.9 14.7 16.1 14.6 13.4 11.9 17.3 0.0 0.0 0.0 0.0 0.0 0.0 13.4 14.8 12.2 0.0 10.0 3.3 10.2 0.0 0.0 0.0 0.0 6.1 7.3 0.0 0.0 2.3 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 10.0 0.0 0.0 10.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269697-38382272 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Cytotrophoblasts: 85.7;Extravillous trophoblasts: 142.9;monocytes: 86.6;Syncytiotrophoblasts: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 19.2 11.3 31.1 15.8 31.4 36.3 20.1 51.5 37.7 18.5 15.5 16.7 14.0 16.2 16.0 12.5 17.0 16.8 17.0 12.7 24.4 16.6 14.2 11.2 17.9 22.3 25.0 26.8 26.5 16.3 21.0 24.2 22.5 21.9 16.4 18.7 12.3 18.3 17.9 12.3 16.2 17.7 16.0 15.3 17.2 19.7 9.3 25.6 16.7 19.2 6.9 20.4 19.6 23.3 26.7 5.6 26.2 5.1 8.6 18.0 2.9 24.1 13.9 23.9 16.1 16.8 19.3 17.7 20.3 22.4 17.6 20.5 7.4 13.4 28.8 18.7 13.8 17.1 14.6 18.9 16.2 25.2 11.4 11.1 36.7 11.2 8.6 17.2 16.1 13.3 10.3 16.5 15.9 32.4 16.5 20.1 31.9 26.0 19.2 16.7 8.7 47.1 13.7 16.2 18.8 6.6 21.6 26.1 9.1 12.5 18.7 13.5 18.2 16.5 14.5 14.1 16.0 18.2 12.3 19.2 18.3 19.0 27.2 11.9 17.1 20.4 27.8 15.5 16.3 13.2 13.9 5.1 9.1 8.0 2.4 5.3 16.5 12.0 7.1 4.1 26.7 15.0 6.3 26.2 8.6 1.5 5.6 18.0 2.9 31.1 31.4 51.5 37.7 24.4 16.6 25.0 26.8 21.9 25.6 62.5 52.3 0.0 0.0 0.0 0.0 0.0 0.0 62.9 55.7 48.8 0.0 85.7 19.9 60.6 0.0 0.0 0.0 0.0 53.3 142.9 0.0 0.0 8.1 0.0 39.1 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 86.6 0.0 0.0 50.3 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 109.4 0.0 0.0 0.0 OGDH E1k ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.3" "Cell type enhanced" "Detected in many" 4 "Cardiomyocytes: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 53000 Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favorable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" 18.9 20.8 12.3 14.5 18.5 8.7 11.0 14.3 23.7 10.1 19.4 15.9 13.5 29.0 16.2 11.1 19.5 11.1 11.8 73.9 11.3 12.8 28.8 14.8 13.0 11.1 14.2 11.7 9.8 13.0 25.5 11.0 14.5 22.2 12.3 13.3 22.3 23.7 15.9 99.3 15.6 35.5 16.4 10.1 12.1 14.9 11.3 11.0 11.3 17.8 39.8 15.8 13.0 10.8 7.2 13.4 7.5 20.4 11.2 25.7 11.6 10.8 22.8 13.7 20.8 21.2 23.3 13.3 17.0 16.6 19.3 16.9 20.7 22.5 47.8 20.2 24.7 39.0 33.8 27.0 25.4 18.9 27.9 7.1 14.5 46.1 10.2 10.8 17.9 16.3 21.6 19.3 27.4 19.7 14.2 26.2 16.0 16.7 14.3 20.4 15.3 17.7 10.3 12.6 30.2 25.7 17.0 9.6 53.6 22.2 32.4 23.4 11.2 24.5 34.1 10.6 25.9 20.2 18.0 20.6 13.9 12.6 24.2 19.6 13.0 24.9 26.4 25.3 20.3 25.3 4.8 12.1 7.3 11.7 17.7 12.8 7.2 13.5 11.7 13.4 5.9 5.8 7.0 7.5 11.2 20.4 6.6 25.7 11.6 12.3 18.5 14.3 23.7 11.3 12.8 14.2 11.7 22.2 11.0 6.0 22.7 20.4 11.1 17.3 20.1 100.7 15.3 12.0 9.1 45.4 17.7 19.4 26.6 13.2 43.1 14.2 61.4 0.0 14.8 14.3 16.4 14.4 20.8 17.5 29.3 58.8 22.4 14.1 22.4 20.0 10.9 21.9 20.3 21.6 29.2 15.4 16.7 21.0 16.3 38.9 22.2 19.4 18.2 9.1 20.0 23.1 30.7 13.8 27.6 14.2 OGDHL FLJ10851 ENSG00000197444 "Oxoglutarate dehydrogenase like" Q9ULD0 10 49734643-49762379 "Citric acid cycle related proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 74.9;liver: 48.8" "Cell type enhanced" "Detected in some" 12 "Bipolar cells: 28.8;Collecting duct cells: 27.9;Cone photoreceptor cells: 29.5;Distal tubular cells: 77.9;Hepatocytes: 45.6;Horizontal cells: 28.6;Proximal tubular cells: 55.6" "Cancer enhanced" "Detected in many" "renal cancer: 44.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "memory CD8 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Cell line enhanced" "Detected in many" "AN3-CA: 13.7;RPTEC TERT1: 28.2;SH-SY5Y: 10.6;SK-BR-3: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043716, HPA052497" Enhanced Approved "Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" "HPA043716: , HPA052497: AB_2681853" "unprognostic (9.05e-2)" "unprognostic (3.93e-3)" "unprognostic (5.30e-2)" "unprognostic (2.50e-1)" "unprognostic (3.70e-3)" "unprognostic (2.03e-1)" "unprognostic (1.46e-3)" "unprognostic (4.19e-1)" "unprognostic (2.07e-1)" "unprognostic (1.46e-2)" "unprognostic (1.52e-3)" "unprognostic (4.60e-1)" "prognostic favorable (1.21e-14)" "unprognostic (3.25e-2)" "unprognostic (1.85e-1)" "unprognostic (1.59e-3)" "unprognostic (8.38e-2)" 0.9 8.1 8.3 1.0 15.3 0.8 0.8 16.2 23.6 1.3 1.3 4.9 2.7 1.4 2.2 1.7 0.9 1.5 1.1 4.1 8.7 13.7 74.9 48.8 0.8 0.9 12.1 11.0 1.9 3.4 23.1 11.7 0.9 23.6 1.8 1.0 8.2 10.3 5.0 0.9 0.8 1.4 1.2 2.9 1.0 1.4 1.9 3.2 0.0 13.0 0.0 1.1 1.4 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 3.0 13.7 0.0 0.0 1.7 0.0 0.0 0.7 0.1 6.6 1.5 0.0 7.4 0.0 2.2 0.2 4.7 0.1 0.2 0.0 0.3 0.0 0.1 3.3 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.4 0.0 3.4 0.3 0.0 0.0 2.0 5.0 4.5 1.3 0.5 0.6 0.0 0.0 0.0 28.2 0.4 7.8 10.6 0.1 10.4 0.7 4.2 2.9 1.8 0.0 0.0 7.1 0.0 0.4 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 15.3 16.2 23.6 8.7 13.7 12.1 11.0 23.6 3.2 0.0 0.0 1.9 0.5 0.0 28.8 3.2 2.5 0.0 0.0 27.9 29.5 0.0 77.9 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 45.6 0.1 28.6 4.6 1.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.1 0.0 0.0 55.6 16.3 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.1 PIPOX LPIPOX ENSG00000179761 "Pipecolic acid and sarcosine oxidase" Q9P0Z9 17 28950513-29057220 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "kidney: 33.5;liver: 114.3" "Group enriched" "Detected in many" 6 "Hepatocytes: 183.0;Proximal tubular cells: 123.0" "Group enriched" "Detected in many" 13 "glioma: 15.5;liver cancer: 73.5" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "AF22: 12.5;Hep G2: 37.6;NTERA-2: 24.8;RH-30: 35.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 390000 "unprognostic (8.02e-2)" "unprognostic (3.50e-4)" "unprognostic (3.03e-1)" "unprognostic (6.25e-3)" "unprognostic (1.52e-1)" "unprognostic (5.01e-2)" "unprognostic (1.95e-3)" "unprognostic (1.15e-2)" "unprognostic (2.17e-1)" "unprognostic (3.45e-1)" "prognostic favorable (1.49e-4)" "unprognostic (2.39e-1)" "unprognostic (3.13e-3)" "unprognostic (2.58e-3)" "unprognostic (2.01e-1)" "unprognostic (2.79e-2)" "unprognostic (1.22e-1)" 0.2 0.2 2.4 0.2 3.1 0.1 0.2 2.2 2.9 0.2 1.4 3.8 0.0 3.1 0.4 5.8 0.5 2.1 0.8 0.2 3.5 2.5 33.5 114.3 0.3 0.3 3.6 3.1 0.3 0.2 0.3 0.2 1.0 4.0 0.5 0.3 0.2 0.2 0.9 0.1 0.2 2.6 0.6 1.7 0.3 0.2 0.2 0.7 0.0 0.1 0.0 0.2 0.3 0.1 0.7 4.7 3.7 0.7 0.9 1.9 0.7 0.0 0.0 12.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.2 0.1 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.2 24.8 0.7 0.0 0.1 35.8 0.7 0.0 0.0 4.0 1.2 0.1 0.0 0.2 2.1 0.0 1.5 0.0 0.0 0.0 0.0 1.6 0.3 4.2 0.1 0.0 0.2 1.2 1.8 0.7 0.7 0.8 0.5 0.9 0.3 0.5 1.2 4.7 0.7 0.3 1.9 3.7 0.9 0.3 0.4 0.8 0.7 2.4 3.1 2.2 2.9 3.5 2.5 3.6 3.1 4.0 0.7 0.0 1.1 2.2 0.2 0.2 1.7 0.4 5.1 0.0 0.0 0.0 3.9 0.1 8.3 0.0 1.3 0.6 0.7 0.0 0.2 4.4 0.4 0.3 5.7 183.0 1.2 0.0 1.2 2.5 3.5 1.5 0.3 1.7 0.0 3.6 0.0 24.0 0.0 0.0 1.1 123.0 1.3 0.0 0.4 0.0 1.0 0.1 0.3 0.5 0.0 0.1 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Extravillous trophoblasts: 215.9;Sertoli cells: 103.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2700000 Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 29.0 19.5 14.9 16.8 24.0 7.1 32.1 12.1 17.6 35.8 21.7 17.0 17.7 19.1 34.2 21.1 16.5 24.7 21.3 31.2 17.6 14.8 27.5 51.3 22.2 19.7 24.5 9.9 31.8 30.3 18.2 16.3 41.5 20.8 21.1 12.0 25.1 39.3 22.0 18.3 13.3 20.8 39.0 13.2 21.1 18.6 10.0 22.4 1.7 34.8 11.1 8.2 19.5 69.7 1.6 16.3 17.7 19.4 2.6 9.1 9.3 16.9 14.5 8.0 37.4 54.7 30.6 6.4 50.4 67.0 26.6 45.3 16.5 11.1 9.8 53.4 55.7 19.8 14.3 11.6 17.6 18.3 10.2 12.4 5.3 23.3 20.9 33.9 3.3 25.8 37.1 9.3 32.1 12.9 90.3 47.1 2.2 14.8 4.8 27.7 11.0 0.8 8.9 3.5 17.3 21.6 3.9 16.3 21.3 15.3 3.8 3.0 12.7 22.0 15.1 25.4 13.1 7.6 8.5 46.5 30.4 22.8 38.0 24.7 11.3 18.3 5.8 67.4 11.6 49.6 0.0 19.4 0.9 9.1 17.2 1.6 1.0 1.6 4.4 16.3 1.6 0.6 3.4 17.7 2.6 15.0 2.4 1.0 9.3 14.9 24.0 12.1 17.6 17.6 14.8 24.5 9.9 20.8 22.4 0.0 9.3 3.7 7.6 6.3 4.2 16.2 10.2 4.0 5.7 10.4 2.0 34.8 3.3 30.5 1.1 20.4 18.7 0.0 8.4 215.9 28.4 9.2 0.0 29.9 41.8 6.4 8.1 46.6 21.6 1.7 41.1 15.6 10.1 18.0 9.8 10.1 24.0 12.9 23.0 13.7 2.7 103.5 26.2 0.5 3.6 4.4 28.1 4.4 11.0 3.8 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.1" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 109.4;Pancreatic endocrine cells: 83.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "HBF TERT88: 82.6;hTERT-RPE1: 93.9;U-87 MG: 73.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 36.7 14.1 11.2 18.0 12.1 0.7 28.5 7.9 13.5 8.8 25.2 5.1 8.3 21.6 14.8 7.5 12.0 8.0 22.3 16.6 12.5 8.2 16.4 73.1 9.3 3.0 10.7 4.8 17.7 14.4 13.9 7.8 41.0 13.0 11.1 16.1 7.2 7.7 11.3 4.8 3.2 24.7 24.2 19.4 3.2 13.6 6.3 10.9 6.1 47.6 3.5 3.0 21.8 28.7 0.0 0.0 1.5 0.3 0.0 0.0 1.9 16.4 11.8 3.7 1.2 13.5 14.5 9.4 58.5 17.9 31.9 60.2 0.9 1.7 0.0 11.4 9.9 14.6 3.5 4.3 50.3 82.6 0.0 6.8 4.1 11.5 8.2 34.7 0.0 0.0 25.4 7.2 27.6 13.5 93.9 44.0 0.0 5.4 0.2 56.3 6.0 0.0 0.0 2.3 0.0 5.1 0.0 2.4 0.0 13.4 0.8 1.8 0.0 46.6 5.0 4.9 18.1 13.6 0.5 55.2 39.5 12.0 12.5 34.9 17.9 2.5 0.0 73.6 0.0 7.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 11.2 12.1 7.9 13.5 12.5 8.2 10.7 4.8 13.0 10.9 14.9 10.7 0.5 5.9 6.3 14.5 10.6 61.1 12.0 13.6 26.2 33.4 6.8 8.3 62.8 0.4 21.2 46.1 0.0 45.9 109.4 34.5 8.1 0.0 50.8 4.7 0.0 19.0 18.4 1.5 1.3 12.0 2.7 13.5 1.0 18.3 65.1 83.0 31.5 4.6 6.9 22.4 19.4 38.1 8.0 16.3 4.8 15.7 0.7 21.3 5.4 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 13.4;monocytes: 14.3;T-cells: 9.2" "Cell line enhanced" "Detected in many" "Karpas-707: 105.8;WM-115: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted - unknown location" NA NA 370000 "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 23.9 16.1 11.9 19.5 24.0 14.6 35.4 7.2 19.2 17.8 20.0 31.2 16.6 22.7 22.9 15.1 11.0 17.4 16.7 22.1 14.8 11.6 20.2 54.1 21.0 18.2 36.3 8.9 16.1 23.2 18.5 16.5 33.1 22.4 14.4 14.2 11.1 11.3 19.6 8.8 14.0 23.2 23.2 29.0 20.4 16.7 10.1 30.6 5.1 16.8 6.0 6.9 17.3 42.6 2.6 13.4 2.8 14.3 2.5 9.2 5.3 10.1 9.2 3.8 25.8 18.4 13.3 7.9 18.7 21.0 19.2 13.9 14.8 13.2 0.8 21.1 32.3 14.8 12.4 7.7 11.0 4.9 5.5 3.5 1.0 11.1 14.4 25.4 4.6 8.7 14.3 10.5 11.2 8.9 18.2 17.0 0.7 9.8 105.8 12.9 29.0 0.4 10.9 8.1 17.5 14.0 3.2 5.2 15.7 6.5 3.0 2.9 17.5 11.6 17.0 41.7 10.7 3.2 15.9 14.8 29.1 14.2 35.2 22.9 5.9 10.8 0.6 17.2 11.1 102.0 0.0 10.8 2.8 9.2 14.3 8.1 2.6 6.8 6.1 10.4 1.8 3.2 3.4 1.0 2.5 14.3 13.4 4.3 5.3 11.9 24.0 7.2 19.2 14.8 11.6 36.3 8.9 22.4 30.6 20.8 8.3 9.0 8.8 7.9 5.1 12.3 17.8 12.0 7.9 24.4 13.7 16.7 1.7 35.7 0.4 23.6 35.9 0.0 27.6 62.3 31.0 7.5 19.6 16.6 45.4 7.9 15.5 27.0 21.6 1.5 24.2 16.4 59.1 20.8 16.2 10.8 29.4 28.1 13.8 10.5 5.9 19.4 17.6 7.2 12.6 4.3 15.8 8.6 21.1 4.2 SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724047-246768137 "Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 95.3" "Group enriched" "Detected in many" 5 "Early spermatids: 1022.4;Spermatocytes: 461.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 17 "basophil: 95.3" "Lineage enriched" "Detected in all" 22 "granulocytes: 95.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 53.5" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA 2100000 Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" 14.1 25.8 15.7 6.4 17.5 13.4 11.3 11.3 20.5 10.9 11.7 24.7 8.5 15.1 12.0 8.5 4.8 14.4 9.7 15.8 15.6 19.8 23.0 67.3 9.3 7.3 26.1 15.0 10.6 12.7 15.0 12.7 14.1 21.7 18.1 12.2 7.3 7.4 16.7 23.9 10.7 15.3 10.8 62.1 5.1 12.4 65.1 17.5 8.5 18.2 7.3 4.8 25.0 13.2 1.4 2.3 95.3 3.2 4.2 3.0 2.1 13.1 12.8 9.4 5.6 11.3 14.2 0.1 10.3 14.4 17.4 14.6 7.8 37.0 7.0 13.5 11.8 9.7 4.3 7.9 3.0 17.9 9.7 2.9 11.8 11.7 15.6 10.6 22.9 10.2 9.5 1.4 11.8 1.2 16.5 18.6 14.7 14.7 0.0 17.3 3.1 23.8 29.1 14.1 7.1 10.2 20.1 12.1 0.0 53.5 30.9 10.7 12.0 13.9 0.6 9.1 5.2 10.4 23.9 12.1 8.1 7.2 19.6 26.5 34.7 11.9 4.1 13.8 31.3 10.6 95.3 3.2 5.5 2.5 2.8 3.0 1.4 0.7 2.1 1.3 1.1 1.0 3.0 0.8 4.2 1.8 2.3 0.5 2.1 15.7 17.5 11.3 20.5 15.6 19.8 26.1 15.0 21.7 17.5 6.0 11.5 8.0 36.7 26.8 29.6 33.1 50.9 52.2 17.0 144.8 17.7 28.0 26.6 57.2 1022.4 20.2 47.9 0.0 61.3 13.6 42.0 76.7 57.5 163.4 83.3 6.4 43.0 21.5 44.3 154.3 44.0 20.4 45.5 15.4 25.1 52.2 56.6 28.1 44.6 51.6 30.6 19.4 27.8 461.4 68.6 59.8 70.7 16.7 53.2 149.1 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA 7400000 "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" 65.5 43.6 18.7 23.3 17.3 36.4 42.6 11.2 15.5 44.4 38.5 23.0 38.8 20.7 41.8 57.9 40.3 27.3 33.2 30.8 18.7 18.4 56.5 68.2 44.7 41.1 24.7 12.6 55.7 70.9 21.2 41.7 46.0 18.4 44.4 28.0 28.5 43.5 36.2 51.9 23.3 33.3 39.7 31.5 38.4 29.5 28.2 19.7 33.2 74.6 39.3 32.1 49.8 37.8 29.1 44.3 32.6 48.4 34.3 45.9 46.3 23.7 51.3 37.9 58.6 48.1 60.0 29.1 38.0 44.3 31.2 37.4 54.9 59.0 11.8 25.0 46.7 36.9 51.9 52.5 31.9 34.0 29.0 38.8 34.5 58.5 51.6 41.7 25.9 39.1 41.3 40.1 21.5 34.9 50.9 44.1 15.5 34.2 31.8 42.1 55.7 10.6 56.4 40.3 36.1 22.1 13.3 49.0 38.5 70.2 66.7 18.6 41.8 31.6 35.4 85.5 59.4 34.5 60.3 30.0 31.7 23.8 27.0 46.2 31.2 59.2 16.7 34.4 45.7 24.7 20.7 43.8 24.1 28.4 47.3 28.5 29.1 35.4 30.4 43.8 26.6 30.2 30.9 32.6 34.3 48.4 44.3 45.9 46.3 18.7 17.3 11.2 15.5 18.7 18.4 24.7 12.6 18.4 19.7 83.4 82.6 129.4 146.5 95.1 26.0 57.2 214.0 68.3 101.2 122.1 21.6 264.5 202.2 211.7 36.2 236.3 103.8 23.3 215.7 493.0 216.8 157.8 217.7 143.3 324.9 19.1 151.1 167.6 353.0 67.9 277.3 291.4 150.1 267.9 172.8 64.3 169.6 103.7 156.3 255.0 33.2 168.1 121.7 176.8 142.9 104.8 255.7 159.2 214.9 195.4 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139477-59158836 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 132.6" "Cell type enhanced" "Detected in all" 5 "Glandular cells: 405.9;Muller glia cells: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 59.5;Karpas-707: 64.1;RPMI-8226: 129.8;U-266/70: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: AB_2680078" "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 5.9 18.4 30.1 18.6 29.7 11.3 16.0 14.9 25.2 12.2 18.7 24.4 27.8 27.5 9.1 58.0 10.7 9.2 11.1 7.2 27.7 33.9 19.0 66.8 13.0 22.0 41.8 21.3 7.0 96.8 14.6 46.6 8.1 27.1 48.8 16.4 10.0 132.6 34.1 4.3 7.9 21.1 6.6 51.3 23.6 28.4 6.4 25.3 7.3 35.9 8.6 23.4 18.9 5.9 33.6 50.0 10.6 17.6 17.3 34.4 32.6 8.8 10.7 5.8 9.0 3.6 0.6 7.4 8.0 6.9 9.9 6.0 7.5 4.8 20.3 12.7 4.8 7.3 9.5 9.1 6.0 5.7 59.5 12.5 6.5 7.4 22.9 10.8 21.5 9.9 2.0 14.4 6.1 16.6 2.1 3.2 8.7 7.5 64.1 3.5 10.4 8.8 8.6 5.9 14.7 6.6 8.0 5.7 129.8 6.4 7.4 27.1 10.8 4.8 19.5 27.1 3.3 8.8 15.8 2.6 12.0 5.0 4.2 9.6 65.4 48.1 19.9 12.0 14.6 14.7 10.6 13.1 9.4 25.9 15.5 33.1 33.6 27.3 25.2 13.5 17.4 14.3 19.5 2.0 17.3 17.6 50.0 34.4 32.6 30.1 29.7 14.9 25.2 27.7 33.9 41.8 21.3 27.1 25.3 26.8 96.0 46.9 40.1 29.0 63.6 51.8 132.5 95.0 89.9 57.6 47.1 59.9 74.6 117.2 35.1 52.2 73.8 23.3 229.6 80.5 24.9 405.9 46.2 201.1 102.0 47.7 325.7 35.6 28.2 14.8 11.5 58.2 243.0 32.5 93.2 440.4 146.8 74.8 21.5 86.0 65.5 6.5 40.9 97.2 84.1 39.6 125.2 74.3 75.9 57.4 SETD1A "KIAA0339, KMT2F, Set1" ENSG00000099381 "SET domain containing 1A" O15047 16 30957294-30984664 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA020646: AB_1856752, HPA058376: AB_2683695" "unprognostic (8.62e-2)" "unprognostic (1.93e-2)" "unprognostic (3.96e-2)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.18e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" "unprognostic (1.70e-2)" "unprognostic (1.94e-1)" 11.0 10.5 10.0 12.4 10.2 25.6 10.3 23.0 14.5 11.1 12.1 14.1 7.6 10.2 15.3 6.7 9.4 11.2 9.7 7.6 8.8 6.7 9.3 10.5 9.0 12.6 9.3 9.8 15.3 14.8 15.6 12.9 11.3 9.5 10.9 5.7 13.5 12.7 10.5 15.2 12.3 11.4 11.7 8.0 14.5 10.3 22.3 10.0 15.5 12.7 5.4 14.1 10.6 9.9 2.0 2.6 2.5 1.4 1.3 1.6 0.9 6.5 12.6 8.7 10.1 5.0 3.5 9.4 7.4 5.5 6.3 5.4 10.7 6.7 17.5 8.2 6.8 6.6 8.6 7.7 7.5 5.2 9.3 30.4 8.1 21.8 12.0 4.8 13.8 13.9 6.0 5.9 8.9 5.7 5.1 4.8 10.3 16.3 9.9 3.4 13.7 16.3 14.0 12.4 4.7 8.4 24.8 8.6 11.0 4.0 7.2 9.4 9.6 9.9 8.2 5.5 5.0 8.5 11.2 6.6 9.6 9.3 6.1 7.7 15.1 18.2 17.1 7.7 12.0 7.2 0.0 0.8 2.5 1.2 1.4 1.6 0.2 1.0 0.8 0.6 2.0 0.7 1.5 0.5 1.3 0.4 2.6 0.4 0.9 10.0 10.2 23.0 14.5 8.8 6.7 9.3 9.8 9.5 10.0 3.0 8.6 7.6 4.7 14.0 7.7 3.2 10.2 2.7 3.4 7.0 5.9 4.0 0.0 3.5 2.6 9.8 4.6 0.0 3.6 3.1 6.1 4.3 3.5 7.7 5.7 12.7 9.9 9.2 3.5 2.2 9.2 3.2 8.5 2.8 6.9 5.6 4.5 6.2 11.0 2.2 5.3 6.5 5.3 12.9 19.8 11.3 2.4 7.5 5.7 3.9 SETD1B "KIAA1076, KMT2G, Set1B" ENSG00000139718 "SET domain containing 1B" Q9UPS6 12 121804180-121832584 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021667, HPA059412" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "HPA021667: AB_1856753, HPA059412: AB_2684006" "unprognostic (1.69e-1)" "unprognostic (2.38e-2)" "unprognostic (6.32e-2)" "unprognostic (3.51e-1)" "unprognostic (2.06e-1)" "unprognostic (2.75e-2)" "unprognostic (5.32e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-2)" "unprognostic (5.65e-2)" "unprognostic (1.59e-2)" "unprognostic (1.75e-1)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 13.8 9.6 9.3 16.8 9.4 22.7 18.1 22.0 11.1 19.6 25.0 7.4 16.0 13.0 27.2 14.8 15.8 21.1 18.2 10.0 8.9 4.6 10.1 10.9 10.9 11.9 5.4 7.4 17.4 14.3 12.1 11.9 12.2 7.1 16.5 6.8 14.4 15.9 31.1 12.9 11.8 15.3 14.7 5.4 14.4 17.8 9.1 7.3 31.1 14.7 8.9 14.7 22.8 14.4 1.3 2.1 3.9 2.0 1.0 2.1 0.8 6.0 12.1 6.4 10.5 6.0 4.1 9.7 5.7 4.7 4.6 2.6 6.8 3.7 4.5 5.3 6.4 2.7 9.5 7.4 4.6 2.6 7.9 9.0 13.9 15.0 5.8 5.1 12.6 11.9 5.0 5.4 6.2 4.9 5.2 4.8 9.0 14.2 3.2 3.1 14.3 18.0 16.7 8.9 2.9 7.4 14.1 4.2 6.4 4.1 12.7 7.9 6.0 13.0 8.7 4.7 4.8 10.8 10.9 8.0 6.5 8.1 9.2 6.3 6.3 3.2 2.7 5.4 7.9 7.4 3.9 0.9 2.0 1.9 2.0 1.3 1.2 1.3 1.8 0.7 1.3 2.1 1.3 3.8 1.0 0.8 2.1 1.3 0.8 9.3 9.4 22.0 11.1 8.9 4.6 5.4 7.4 7.1 7.3 3.0 5.3 2.4 3.2 10.4 12.0 8.3 7.6 0.0 6.8 5.2 7.9 6.5 0.0 4.5 7.5 9.3 5.5 0.0 6.2 5.9 7.4 6.7 3.5 11.9 5.7 11.1 7.0 12.9 21.6 14.4 10.6 5.6 1.7 1.0 7.3 5.3 5.7 9.5 9.6 3.0 8.4 6.5 7.2 12.5 1.0 11.3 11.0 8.5 6.7 6.5 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2" Q9BYW2 3 47016429-47163967 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favorable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 13.2 10.5 12.2 15.2 15.4 20.0 11.7 22.4 16.4 13.4 14.0 9.1 12.9 9.5 15.8 7.5 10.8 11.4 8.7 8.8 10.6 6.8 11.4 10.3 10.4 11.8 11.7 9.5 16.0 13.4 21.4 16.3 10.7 11.3 12.4 10.9 7.7 12.7 14.8 27.6 12.5 11.5 11.9 9.8 13.8 10.4 12.8 12.8 23.2 15.8 5.5 12.8 16.1 15.5 4.8 2.6 6.0 2.3 7.1 3.9 1.0 11.6 9.2 15.4 7.9 9.3 10.7 6.5 10.7 10.4 12.6 11.5 9.7 7.6 25.7 6.7 14.8 12.3 7.1 16.7 10.2 17.1 14.7 6.6 26.4 15.3 7.5 7.0 19.7 15.3 9.2 9.9 12.4 15.4 10.2 11.6 13.3 16.9 9.7 10.3 6.1 14.5 2.6 11.7 5.6 7.7 9.6 15.0 13.3 6.4 15.3 6.7 10.6 18.1 7.1 6.7 11.5 7.5 14.7 14.8 13.9 10.4 11.8 17.1 12.5 13.9 26.0 8.0 11.3 8.1 2.4 2.2 5.2 3.9 2.3 2.4 3.7 2.4 3.0 2.5 4.8 3.5 3.0 6.0 7.1 1.9 2.6 1.0 1.0 12.2 15.4 22.4 16.4 10.6 6.8 11.7 9.5 11.3 12.8 44.7 53.3 20.6 20.5 29.7 33.4 58.5 22.9 66.9 80.8 10.4 39.3 16.3 10.0 17.4 24.0 29.3 26.5 0.0 19.3 10.1 20.8 25.9 55.6 26.7 14.3 25.4 21.2 23.4 27.2 20.8 28.1 21.6 16.9 20.8 27.8 21.7 20.0 17.5 31.1 9.3 37.0 12.9 21.7 78.1 18.9 31.1 15.4 27.7 24.8 34.2 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing lysine methyltransferase 7" Q8WTS6 4 139495941-139606699 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Hepatocytes: 64.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: AB_2683607" "prognostic unfavorable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 26.1 13.2 12.0 9.6 12.3 5.7 26.3 10.2 16.2 27.9 17.7 17.9 11.0 4.8 23.8 12.0 18.3 13.8 16.9 25.2 13.0 10.0 7.2 30.7 12.1 6.9 18.0 10.1 13.3 13.8 26.8 9.3 12.0 15.4 22.8 10.2 12.4 13.7 13.9 56.4 14.2 9.9 33.3 19.0 11.8 17.7 10.6 16.5 2.9 10.3 15.2 9.9 24.2 30.1 2.3 6.8 1.8 5.6 0.5 5.6 1.6 9.0 11.7 4.5 2.6 26.5 22.9 9.9 21.5 22.4 11.0 9.3 6.9 12.4 21.1 8.5 36.2 7.6 4.6 14.9 17.0 17.9 10.4 10.5 2.9 15.3 0.2 13.1 10.1 4.5 19.8 19.9 17.5 18.7 14.0 13.9 9.0 1.7 32.9 14.0 15.1 6.6 1.5 2.2 13.3 7.7 6.2 15.5 12.1 10.7 8.3 17.4 5.8 14.3 21.3 5.1 4.5 8.4 9.2 22.5 19.5 13.9 23.2 17.8 28.4 27.2 13.4 22.5 10.2 9.3 1.0 5.6 0.5 0.6 3.2 4.1 1.8 1.8 1.8 6.8 2.3 0.8 0.5 1.8 0.5 4.8 3.5 5.6 1.6 12.0 12.3 10.2 16.2 13.0 10.0 18.0 10.1 15.4 16.5 6.0 13.1 3.4 10.9 15.2 6.6 35.4 17.8 4.0 6.8 8.7 11.8 21.9 0.0 20.5 0.9 24.7 1.8 23.3 18.1 14.4 19.2 35.1 2.3 64.4 18.3 7.9 1.2 36.8 29.7 3.5 21.3 18.3 10.1 7.2 11.2 13.3 21.5 0.0 26.5 3.9 12.6 19.4 21.0 3.2 1.9 19.3 38.6 5.0 9.9 14.2 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "U-698: 90.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: AB_2683731" "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 16.9 15.4 9.5 21.2 15.9 16.9 17.7 21.6 18.2 18.6 15.4 25.2 18.6 13.0 22.8 18.9 15.6 16.8 14.0 10.9 9.6 8.5 13.3 12.7 15.6 20.7 15.3 13.2 23.9 17.6 21.0 15.4 18.4 13.7 14.9 16.8 20.6 16.1 18.5 20.0 18.0 17.1 17.9 13.7 21.9 15.0 33.5 14.2 24.5 18.6 12.0 20.7 18.6 16.3 11.2 12.8 6.9 14.9 7.6 9.1 5.3 5.9 6.9 10.0 6.6 4.8 6.4 16.7 4.9 5.7 7.1 6.1 4.6 8.2 11.6 6.8 5.4 2.8 7.4 9.3 5.3 5.6 5.6 11.5 6.6 7.1 5.3 6.8 11.6 6.3 8.4 5.9 5.8 9.5 7.2 8.3 7.5 11.0 9.5 5.0 11.4 8.0 6.8 13.7 8.3 5.5 9.3 6.5 8.6 5.4 6.8 7.3 13.3 7.5 8.8 5.9 12.6 9.5 15.7 5.6 4.1 4.3 4.5 6.8 9.9 10.6 90.6 4.3 4.1 4.0 6.8 10.7 6.9 8.3 14.9 8.7 8.7 7.4 9.1 12.8 11.2 8.3 8.3 6.5 7.6 10.6 8.6 4.7 5.3 9.5 15.9 21.6 18.2 9.6 8.5 15.3 13.2 13.7 14.2 6.0 12.3 5.3 7.2 4.8 10.9 4.1 5.1 9.4 6.8 7.0 17.7 11.4 3.3 6.6 23.5 6.9 6.2 0.0 5.0 7.2 4.9 6.2 7.0 6.2 8.8 6.4 3.5 10.4 14.2 21.8 9.5 10.4 1.7 7.2 10.3 6.3 7.3 10.7 9.2 5.4 10.1 6.5 5.9 22.4 14.5 4.4 8.4 7.0 9.3 6.4 SETDB2 "C13orf4, CLLD8, CLLL8, KMT1F" ENSG00000136169 "SET domain bifurcated 2" Q96T68 13 49444374-49495003 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012190, HPA071677" Approved Approved Nucleoplasm No No Nucleoplasm "CAB012190: AB_2186195, HPA071677: AB_2686430" "unprognostic (1.77e-1)" "unprognostic (1.11e-2)" "unprognostic (1.58e-1)" "unprognostic (3.61e-2)" "unprognostic (4.20e-1)" "unprognostic (3.70e-3)" "unprognostic (3.74e-2)" "unprognostic (3.44e-3)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.09e-3)" "unprognostic (7.95e-2)" "prognostic favorable (1.92e-7)" "unprognostic (2.83e-2)" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.85e-1)" 10.2 14.5 9.8 20.5 10.8 9.5 14.1 14.4 12.3 13.0 12.4 8.3 13.6 7.8 13.1 11.6 9.8 9.9 9.7 12.7 8.2 6.9 12.4 11.0 16.3 19.0 7.2 11.1 21.0 15.0 10.8 15.8 7.8 9.5 13.6 11.9 13.5 11.7 10.9 5.5 9.6 11.4 11.3 8.4 19.0 10.7 18.1 8.7 17.3 14.6 3.7 16.6 11.9 10.3 8.4 7.4 4.7 5.4 7.8 10.2 4.5 2.0 1.4 4.3 4.4 6.1 6.9 2.2 5.9 7.4 5.3 5.0 8.7 5.0 25.7 1.2 3.8 4.0 4.2 4.5 4.0 5.2 5.8 3.9 8.9 3.9 5.2 8.6 13.5 5.1 5.3 7.4 4.0 13.4 5.8 4.5 8.3 3.9 3.6 4.8 1.8 5.1 10.1 2.2 5.5 3.4 10.0 5.4 5.4 4.9 1.9 2.2 2.6 2.6 3.7 12.6 3.9 3.1 11.8 2.7 5.1 1.8 6.8 2.4 4.3 6.0 13.6 1.6 11.0 2.3 4.1 4.1 4.7 6.9 5.4 5.8 8.4 7.1 7.1 7.4 8.1 10.2 7.6 1.4 7.8 4.3 5.2 9.4 4.5 9.8 10.8 14.4 12.3 8.2 6.9 7.2 11.1 9.5 8.7 26.8 14.1 32.7 5.3 6.2 12.6 22.4 10.2 13.4 10.3 5.2 25.5 4.8 8.3 3.3 14.7 8.2 6.9 0.0 3.8 2.9 5.1 3.0 5.8 5.9 15.9 12.7 11.1 5.5 19.0 11.1 9.2 17.4 13.5 10.0 6.2 10.8 3.1 2.9 7.8 3.4 29.6 0.0 5.2 18.2 11.8 5.3 2.4 19.1 8.5 2.0 SETMAR metnase ENSG00000170364 "SET domain and mariner transposase fusion gene" Q53H47 3 4303304-4317567 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Methyltransferase, Multifunctional enzyme, Nuclease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA057999 Supported Nucleoli NA NA Nucleoli "HPA057999: AB_2683574" "unprognostic (1.59e-1)" "unprognostic (1.22e-2)" "unprognostic (5.24e-3)" "unprognostic (4.89e-2)" "unprognostic (7.73e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.58e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-1)" "unprognostic (1.19e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.61e-6)" "unprognostic (5.42e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.26e-3)" 14.1 6.2 7.3 7.2 9.2 3.7 14.2 6.9 8.5 12.5 6.5 6.2 5.2 4.3 19.4 7.6 7.2 12.5 8.2 6.3 6.6 4.3 10.1 5.3 5.1 6.5 9.1 8.7 19.4 9.8 5.7 7.4 5.6 6.5 13.9 6.9 5.7 11.9 10.0 7.7 7.3 5.7 16.8 7.2 5.0 6.0 7.3 10.8 13.1 11.5 8.3 4.4 11.3 13.3 3.8 1.6 1.9 3.3 0.5 5.3 1.5 3.0 2.7 8.2 1.7 19.7 6.5 8.3 3.3 1.0 3.3 3.1 2.8 2.3 8.0 3.5 1.8 6.0 2.6 7.2 5.0 3.6 5.4 6.2 10.0 4.9 4.5 2.3 4.7 4.2 7.7 3.9 2.4 0.8 3.0 4.8 9.1 6.6 3.0 5.1 4.1 7.0 3.0 8.0 1.9 4.7 8.3 8.1 3.3 3.1 4.2 6.5 9.6 4.0 5.0 4.3 5.4 4.8 2.7 3.1 4.9 6.9 4.1 4.3 4.0 9.5 19.8 1.8 5.4 4.1 1.9 1.1 1.3 2.3 3.3 2.0 2.9 2.7 2.9 1.0 3.8 4.5 5.3 0.2 0.5 1.9 1.6 1.7 1.5 7.3 9.2 6.9 8.5 6.6 4.3 9.1 8.7 6.5 10.8 0.0 5.3 2.7 7.6 2.2 5.2 5.9 5.1 9.4 13.6 0.0 0.0 20.4 11.6 10.1 0.6 6.8 2.3 0.0 11.6 12.2 7.4 3.2 1.1 2.5 5.2 0.0 3.5 3.7 1.0 0.9 8.9 1.8 0.0 4.6 2.6 4.1 6.6 5.1 12.4 4.3 2.8 6.5 5.7 4.6 5.1 0.5 13.6 1.3 5.6 3.1 SHMT2 SHMT ENSG00000182199 "Serine hydroxymethyltransferase 2" P34897 12 57229327-57234935 "Enzymes, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.1" "Cell type enhanced" "Detected in many" 6 "Hepatocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 212.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020543, HPA020549" Enhanced Supported Microtubules,Mitochondria NA NA 160000 Mitochondria Microtubules "HPA020543: AB_1856833, HPA020549: AB_1856834" "prognostic unfavorable (8.37e-5)" "unprognostic (1.24e-1)" "unprognostic (1.90e-1)" "unprognostic (2.65e-2)" "unprognostic (1.65e-1)" "unprognostic (4.97e-2)" "unprognostic (1.58e-2)" "unprognostic (9.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.67e-2)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (4.84e-8)" "unprognostic (3.05e-1)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (4.74e-2)" 13.0 13.5 5.9 15.0 7.1 12.6 9.5 9.6 9.5 10.5 11.5 6.1 5.0 13.4 10.2 8.5 22.1 8.6 10.3 11.0 6.5 5.4 15.5 103.1 11.8 18.7 8.7 4.6 17.9 38.9 4.5 8.1 16.8 6.5 10.3 9.4 7.1 44.6 5.7 16.5 13.7 11.5 9.9 7.6 23.5 13.4 5.4 6.3 26.1 13.2 19.0 25.6 11.2 13.8 33.6 14.5 6.5 11.7 9.7 48.7 12.3 25.1 11.7 11.8 31.2 9.3 14.3 23.4 13.6 22.2 18.3 16.8 16.7 12.2 46.6 22.6 16.8 7.6 16.1 21.3 22.2 9.9 26.0 19.0 19.2 7.2 11.8 68.7 31.7 17.0 18.3 32.2 14.7 49.2 16.6 18.1 24.8 20.0 44.3 13.8 16.5 25.2 17.4 10.1 10.1 19.0 17.0 212.4 43.1 9.1 11.6 25.3 12.1 7.1 16.8 49.3 4.5 22.8 39.0 11.4 7.4 15.1 9.6 18.5 59.5 32.5 39.5 16.0 29.6 13.3 6.5 9.8 5.9 6.9 11.7 8.0 33.6 12.1 7.4 14.5 32.4 5.3 5.4 0.5 9.7 7.5 4.8 48.7 12.3 5.9 7.1 9.6 9.5 6.5 5.4 8.7 4.6 6.5 6.3 8.9 13.1 58.9 19.1 30.8 6.2 7.5 20.4 9.4 12.5 3.5 0.0 53.0 11.6 41.7 0.4 13.5 11.0 46.7 41.3 42.8 21.6 14.9 28.8 158.5 43.3 7.9 9.2 20.3 38.1 0.2 16.7 22.7 37.1 27.1 21.6 42.4 40.1 21.0 15.2 48.7 4.9 6.5 22.6 2.1 7.2 28.4 31.2 26.2 37.7 17.6 SMYD3 "KMT3E, ZMYND1, ZNFN3A1" ENSG00000185420 "SET and MYND domain containing 3" Q9H7B4 1 245749342-246507312 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "granulocytes: 108.5;Late spermatids: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 95.1;K-562: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012229, HPA045821, HPA054352" Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB012229: , HPA045821: AB_2679461, HPA054352: AB_2682458" "unprognostic (7.00e-3)" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (6.18e-3)" "unprognostic (3.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.25e-3)" "unprognostic (1.72e-3)" "unprognostic (4.53e-2)" "unprognostic (1.57e-1)" "unprognostic (1.71e-1)" "unprognostic (2.10e-1)" "unprognostic (3.78e-5)" "unprognostic (9.03e-3)" "unprognostic (2.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.58e-1)" 6.0 12.0 9.9 9.7 16.2 7.6 10.6 25.9 14.7 8.9 6.5 6.4 3.7 4.5 8.7 21.8 6.1 10.0 7.7 5.8 10.3 12.0 8.9 5.5 9.2 6.3 12.0 10.2 8.0 7.2 6.7 11.9 4.6 15.3 6.8 8.3 9.5 5.3 5.9 9.5 6.7 5.2 7.6 6.8 5.3 6.1 10.5 8.1 7.5 18.8 3.6 9.3 8.3 6.6 11.3 5.9 8.3 3.4 19.4 12.9 8.7 4.7 2.9 4.2 3.6 4.8 6.6 4.2 6.7 5.0 7.9 17.8 3.7 5.5 7.7 5.4 6.2 4.9 3.1 3.8 7.5 26.5 4.0 3.9 4.5 4.3 4.5 9.0 4.6 95.1 17.7 1.8 10.4 6.7 6.0 5.4 5.5 35.9 2.7 7.7 1.6 8.7 8.8 3.7 6.6 4.7 8.1 5.1 11.2 5.7 6.9 10.0 4.8 3.1 0.4 6.1 4.7 3.9 7.8 4.1 3.8 2.6 2.7 7.9 13.6 3.7 4.0 7.3 6.3 4.4 8.1 3.4 8.3 10.5 3.0 10.8 11.3 11.1 12.8 5.9 11.1 12.3 12.9 2.4 19.4 3.3 3.8 11.8 8.7 9.9 16.2 25.9 14.7 10.3 12.0 12.0 10.2 15.3 8.1 6.0 27.8 5.3 13.2 10.9 5.8 7.7 2.5 44.2 13.6 12.2 21.6 7.8 13.3 20.6 46.2 11.7 4.2 0.0 28.1 33.5 15.4 5.4 108.5 4.2 10.3 9.5 24.1 9.2 3.8 74.1 10.3 6.0 11.8 1.8 8.3 9.1 16.5 2.9 16.3 14.6 13.9 0.0 15.1 17.3 24.7 10.0 6.1 13.6 9.2 6.4 SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711146 "Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" 31.0 53.4 39.7 28.5 41.5 27.5 42.2 24.2 55.3 39.1 46.3 40.8 46.3 47.8 34.9 53.2 39.1 33.9 35.6 39.4 38.0 47.0 62.3 98.7 37.1 68.9 47.2 38.1 34.7 112.1 30.5 48.8 50.9 41.7 41.0 41.6 38.4 87.7 57.8 43.2 34.3 53.4 34.2 48.3 37.4 45.7 57.1 25.5 42.6 55.2 38.3 52.0 36.6 30.2 40.2 123.4 48.5 27.8 22.2 34.1 43.1 21.5 20.5 19.5 25.2 31.5 25.7 32.5 30.0 27.5 27.2 24.5 21.4 31.6 23.1 13.2 27.1 26.0 20.8 19.7 28.0 26.5 30.8 23.7 27.3 34.0 29.8 35.6 37.8 45.2 21.0 36.8 30.0 32.7 22.3 22.0 29.0 23.2 73.4 27.7 20.9 29.9 38.4 37.1 53.1 42.6 12.2 18.2 116.3 40.0 26.6 14.1 31.8 29.5 31.7 39.8 18.0 35.4 43.4 20.8 24.6 23.1 44.0 35.3 81.0 120.8 32.6 38.1 41.8 32.0 45.3 26.0 48.5 27.8 26.0 32.8 40.2 34.1 30.5 28.4 29.0 32.2 32.8 19.8 22.2 27.8 123.4 33.9 43.1 39.7 41.5 24.2 55.3 38.0 47.0 47.2 38.1 41.7 25.5 59.6 94.5 189.7 185.2 139.0 485.2 136.5 219.1 186.0 126.3 294.8 111.9 309.5 306.7 288.1 445.8 151.7 198.8 93.5 296.3 331.3 163.9 238.4 205.7 300.1 274.6 96.9 161.0 125.8 194.0 878.2 200.2 191.2 361.0 334.6 203.8 220.7 242.0 238.9 180.4 563.8 195.8 161.7 195.7 623.3 495.0 161.2 293.7 203.7 226.0 258.6 SPCS2 KIAA0102 ENSG00000118363 "Signal peptidase complex subunit 2" Q15005 11 74949247-74979031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013386 Approved Approved Nucleoplasm NA NA 220000 Nucleoplasm "HPA013386: AB_1857426" "unprognostic (2.43e-1)" "unprognostic (7.01e-2)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (9.30e-2)" "unprognostic (2.31e-2)" "unprognostic (7.04e-3)" "unprognostic (9.61e-2)" "unprognostic (8.83e-2)" "unprognostic (2.02e-3)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (5.70e-2)" "unprognostic (1.37e-1)" "unprognostic (8.62e-2)" 21.8 32.8 29.1 25.8 29.2 13.4 28.7 20.0 26.8 36.5 30.4 26.8 49.5 23.2 32.3 61.6 23.3 25.8 21.4 25.2 29.8 27.5 30.0 46.5 24.0 25.3 33.4 33.5 24.0 75.5 41.6 26.7 28.5 32.9 29.2 31.1 18.6 55.9 34.9 26.4 17.2 24.0 24.8 33.4 30.1 26.5 24.2 27.6 20.3 43.9 14.9 38.7 23.8 21.4 78.2 89.7 86.4 45.9 47.9 65.4 71.8 22.3 26.3 35.2 31.5 31.0 20.9 19.2 32.1 31.4 29.6 26.0 51.7 50.8 36.4 40.7 27.1 35.4 41.3 30.4 23.5 37.0 30.0 22.3 36.9 32.0 42.6 35.3 39.1 26.0 18.5 30.7 24.9 41.0 26.1 28.3 26.9 42.4 95.0 26.8 34.0 27.8 25.0 21.5 88.9 25.1 34.7 54.2 82.5 34.1 37.4 28.6 28.7 32.0 43.1 105.2 25.5 41.7 30.0 22.8 33.8 21.0 35.0 28.3 40.6 41.0 67.6 13.9 27.8 34.1 86.4 45.9 41.3 58.3 44.4 65.4 78.2 54.0 55.9 43.4 62.1 41.4 49.6 29.6 47.9 38.2 89.7 50.9 71.8 29.1 29.2 20.0 26.8 29.8 27.5 33.4 33.5 32.9 27.6 80.4 121.2 168.1 276.8 270.4 92.5 52.0 203.8 105.7 150.2 226.8 49.1 294.6 160.8 248.0 23.5 169.0 110.2 186.9 251.0 262.7 270.0 340.7 151.3 327.2 251.3 90.6 120.3 149.8 135.4 21.2 222.9 194.9 494.3 215.6 135.9 198.0 231.8 129.8 183.9 236.3 72.2 168.1 200.5 94.2 127.2 200.6 388.7 197.1 133.3 256.7 SPCS3 "FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W" ENSG00000129128 "Signal peptidase complex subunit 3" P61009 4 176319964-176332245 "Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 88.1" "Low region specificity" "Detected in all" HPA053180 Approved NA NA "HPA053180: AB_2682071" "unprognostic (4.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.20e-3)" "prognostic favorable (8.89e-6)" "unprognostic (1.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.79e-2)" "unprognostic (4.78e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.58e-2)" "unprognostic (2.85e-1)" "unprognostic (2.26e-1)" "unprognostic (4.92e-2)" "unprognostic (2.16e-2)" "unprognostic (1.44e-1)" 20.3 14.2 15.5 24.5 15.8 29.3 30.0 18.3 24.9 26.2 25.3 12.6 40.9 17.3 23.5 27.4 18.2 19.2 20.0 24.4 14.1 14.5 18.1 41.3 25.4 38.2 18.9 17.5 15.8 85.0 21.2 24.9 26.3 14.6 17.6 19.8 11.0 52.4 37.4 17.4 16.2 18.6 26.4 21.2 29.5 24.5 8.3 12.9 19.1 32.5 16.1 23.8 22.4 19.5 8.0 17.1 26.2 14.6 13.0 16.3 12.8 14.6 4.9 13.7 11.2 19.6 34.8 14.5 29.0 27.9 17.0 14.7 5.3 32.4 28.3 6.0 16.7 8.9 10.2 12.9 21.4 25.9 19.0 5.7 24.4 8.0 12.1 20.0 36.5 21.6 21.0 23.6 15.0 14.6 19.1 25.0 13.8 15.7 88.1 23.3 8.9 22.2 13.9 9.3 10.4 4.9 11.0 21.3 24.6 20.9 10.7 10.9 10.0 30.3 22.7 13.3 12.4 7.3 17.1 23.2 12.6 12.6 11.2 13.2 40.9 12.1 35.6 26.8 18.5 17.3 26.2 12.2 10.3 12.3 14.6 16.3 8.0 11.5 11.1 9.2 5.3 9.7 12.0 12.2 13.0 11.6 17.1 8.9 12.8 15.5 15.8 18.3 24.9 14.1 14.5 18.9 17.5 14.6 12.9 50.6 81.3 47.6 49.0 50.8 32.2 67.8 40.8 42.8 54.6 27.9 25.5 58.7 18.3 68.9 48.1 87.5 44.5 116.8 117.4 151.8 62.7 93.0 89.0 104.2 140.2 22.3 43.0 92.1 105.2 14.2 20.8 125.0 104.6 64.9 66.2 31.5 141.6 34.5 15.9 52.2 28.5 12.9 51.2 75.3 39.6 57.0 154.2 63.7 42.2 96.6 SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "Suppressor of variegation 3-9 homolog 1" O43463 X 48695554-48709012 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Extravillous trophoblasts: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (4.92e-2)" "prognostic favorable (8.93e-5)" "unprognostic (9.51e-2)" "unprognostic (4.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.91e-7)" "unprognostic (2.29e-3)" "unprognostic (6.47e-3)" "unprognostic (2.01e-1)" "unprognostic (5.67e-2)" 5.7 3.3 6.5 6.4 7.6 18.0 4.9 8.7 12.5 7.0 5.1 9.3 6.0 5.1 5.7 20.7 7.3 5.3 3.4 6.0 6.0 8.3 5.0 9.2 4.6 10.8 8.8 6.9 6.5 4.4 3.6 4.7 9.3 6.7 4.5 5.4 8.3 6.5 5.4 6.9 7.0 6.0 4.7 6.2 9.5 5.2 6.7 5.9 21.2 3.9 6.4 10.7 4.8 3.5 5.8 2.8 7.1 6.4 10.7 11.7 6.8 14.8 18.2 7.2 7.6 1.8 2.2 14.7 7.2 5.5 14.1 11.5 11.1 10.0 16.5 4.4 5.2 14.3 10.5 17.8 10.2 8.5 12.5 18.2 6.5 16.9 9.0 1.1 15.9 3.6 2.0 2.0 12.4 6.4 2.3 10.0 10.8 16.3 11.6 7.6 17.2 13.6 16.6 8.5 7.3 17.7 10.0 13.3 17.4 4.6 8.3 9.5 6.2 9.8 9.5 5.2 8.4 14.1 13.3 5.3 8.7 15.0 12.0 12.1 8.0 12.0 13.9 6.5 22.9 9.5 4.5 3.0 7.1 9.8 4.4 7.2 5.3 6.5 10.3 2.4 5.8 8.1 7.7 2.1 10.7 6.4 2.8 11.7 6.8 6.5 7.6 8.7 12.5 6.0 8.3 8.8 6.9 6.7 5.9 6.0 0.0 7.7 0.8 1.5 4.9 2.2 0.0 4.0 1.2 1.8 0.0 4.4 3.3 1.8 0.1 0.9 1.6 0.0 2.5 24.4 1.4 0.4 1.1 5.6 4.5 0.0 2.9 1.8 1.9 0.0 1.1 2.5 5.0 3.6 1.5 0.6 1.8 1.7 1.4 1.4 3.5 0.0 1.2 1.5 0.8 1.0 5.1 4.5 1.6 0.3 SUV39H2 "FLJ23414, KMT1B" ENSG00000152455 "Suppressor of variegation 3-9 homolog 2" Q9H5I1 10 14878820-14904315 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Cell type enhanced" "Detected in many" 22 "Early spermatids: 302.5;Late spermatids: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045901, HPA057554" Enhanced Approved Mitochondria NA NA Mitochondria "HPA045901: AB_10960702, HPA057554: AB_2683466" "prognostic unfavorable (5.55e-4)" "unprognostic (1.45e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-3)" "unprognostic (6.80e-2)" "unprognostic (1.23e-3)" "prognostic unfavorable (2.01e-6)" "unprognostic (1.06e-1)" "unprognostic (9.15e-2)" "unprognostic (3.59e-3)" "unprognostic (2.42e-1)" "unprognostic (4.13e-3)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" "unprognostic (5.55e-2)" "unprognostic (1.39e-1)" 3.0 2.9 4.7 3.4 7.4 4.9 5.2 20.0 8.6 3.1 3.8 1.6 2.1 3.2 3.8 2.3 4.0 3.0 3.2 2.4 5.4 2.8 3.5 3.8 2.7 3.6 3.3 4.4 4.2 2.4 2.4 6.3 5.1 3.3 3.9 4.7 1.6 2.4 3.6 2.4 3.3 2.9 3.7 3.0 3.4 2.7 41.8 4.4 10.3 2.8 4.9 4.0 3.3 2.8 0.8 3.1 0.5 1.8 5.6 4.0 0.8 13.7 13.1 22.0 12.5 4.1 5.0 8.6 7.5 4.6 14.0 19.9 19.6 7.9 11.1 6.8 4.5 12.3 9.7 16.3 9.1 17.3 11.3 10.8 16.7 9.3 12.1 2.4 7.5 8.0 2.4 3.2 14.2 4.4 3.1 9.6 18.9 21.5 7.5 10.3 13.5 14.8 2.1 13.6 12.6 3.5 18.4 14.5 8.9 5.9 6.6 7.3 8.1 11.7 7.3 6.3 13.5 12.9 6.5 5.6 10.1 16.3 12.3 11.9 4.3 16.1 25.5 6.2 8.2 6.5 0.5 0.4 0.3 2.8 1.8 4.0 0.8 2.4 3.5 2.2 0.6 3.8 3.6 0.3 5.6 0.5 3.1 3.7 0.8 4.7 7.4 20.0 8.6 5.4 2.8 3.3 4.4 3.3 4.4 0.0 1.0 0.0 7.0 7.3 7.4 2.4 0.0 4.0 7.9 1.8 9.8 11.4 5.0 3.5 302.5 5.2 0.9 0.0 1.8 20.4 5.5 6.6 2.3 2.9 4.3 11.1 3.4 1.8 1.8 78.4 4.4 2.4 1.7 1.0 2.8 2.4 2.2 1.1 2.5 5.0 9.8 6.5 6.6 37.0 52.7 7.8 7.4 1.8 3.9 10.9 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155490115-155669944 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA Mitochondria "HPA034589: AB_10670571, HPA040331: AB_2676929" "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favorable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 10.1 15.0 8.5 6.7 10.5 6.7 10.4 17.1 13.5 11.3 10.5 10.0 9.1 10.7 10.9 10.1 9.5 9.5 7.4 22.3 10.3 7.5 15.8 16.9 6.9 14.6 12.5 7.4 12.4 10.7 18.4 17.5 7.6 11.5 7.7 11.6 10.6 16.2 9.6 28.1 7.8 10.0 13.8 13.7 9.2 9.8 3.1 11.2 12.2 10.5 5.3 8.7 10.2 9.1 9.1 10.3 14.7 15.7 4.3 5.6 4.5 15.2 7.5 6.2 18.1 7.7 11.9 0.0 6.2 9.1 7.8 20.4 5.3 8.6 0.0 25.0 10.8 18.0 8.3 13.2 6.0 8.9 6.2 9.0 6.8 12.2 6.2 10.8 6.4 4.9 12.6 12.7 8.7 13.2 11.7 12.3 9.8 9.5 5.6 12.9 5.7 7.7 7.2 1.9 13.2 0.1 7.7 9.9 5.8 9.4 5.2 5.9 8.9 5.8 0.3 6.7 7.0 6.7 7.3 10.3 6.6 6.3 13.0 7.6 7.0 7.5 5.8 8.0 10.0 6.0 1.9 10.1 11.3 3.9 11.4 2.9 6.2 4.3 3.3 10.3 9.1 5.6 4.9 14.7 4.3 15.7 4.7 4.2 4.5 8.5 10.5 17.1 13.5 10.3 7.5 12.5 7.4 11.5 11.2 0.0 2.9 10.0 9.7 4.6 3.6 6.5 7.6 9.4 4.5 8.7 0.0 7.2 19.9 8.9 0.0 5.6 8.6 0.0 6.6 5.8 7.5 2.7 9.3 11.3 10.9 0.0 5.8 5.5 14.6 0.0 7.8 11.4 11.8 10.8 6.9 7.2 8.0 7.0 5.3 11.3 5.2 0.0 8.2 0.4 1.7 3.6 5.6 6.9 7.6 8.7