Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814037-151828488 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 66.2;intestine: 81.7;liver: 123.1" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 610.4" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Region enriched" "Detected in single" 7 "basal ganglia: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 11.9;ASC diff: 4.5;EFO-21: 6.4;HBEC3-KT: 5.7" "Not detected" "Not detected" HPA002911 Approved NA NA "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.58e-6)" "prognostic unfavorable (5.02e-4)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" 3.9 66.2 0.1 0.1 1.6 0.0 2.1 0.1 0.1 0.1 26.1 0.5 0.4 29.6 0.1 0.3 0.3 0.2 4.3 0.2 0.1 0.0 0.1 123.1 1.7 0.1 0.1 0.1 0.1 22.7 0.0 0.1 1.7 0.2 0.3 0.0 0.1 0.3 0.1 0.2 1.7 81.7 0.1 0.1 0.1 7.3 0.3 0.1 0.1 0.2 4.8 1.3 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 4.5 0.2 0.3 0.0 0.0 0.1 0.0 1.1 0.1 0.2 6.4 0.0 0.1 0.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.7 0.1 0.1 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.2 1.4 0.3 0.2 0.4 2.1 0.0 2.3 0.2 1.9 0.3 0.1 0.0 0.0 0.0 0.0 2.5 0.0 2.4 1.4 0.0 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 11.0 0.0 0.0 0.2 0.0 1.1 58.6 4.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.2 0.0 0.0 610.4 0.2 0.0 0.0 3.7 10.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.2 0.0 0.0 0.1 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 109.7" "Cell type enhanced" "Detected in all" 9 "Cone photoreceptor cells: 732.4;Rod photoreceptor cells: 621.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA No "Vesicles, Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 5.1 5.9 11.0 5.7 11.9 7.8 6.9 25.2 26.5 4.8 4.2 3.9 6.3 3.8 4.7 7.1 3.8 4.9 4.3 7.9 14.4 12.8 7.2 3.1 7.5 6.8 9.4 11.6 3.3 6.7 109.7 10.3 6.9 10.2 5.0 4.6 4.7 3.6 12.3 6.8 3.7 3.7 5.4 9.3 5.5 5.4 4.1 6.9 4.7 16.0 2.1 5.3 4.9 5.8 1.0 0.8 4.1 3.9 2.8 5.6 1.3 16.8 10.1 9.3 9.0 8.9 9.9 29.9 13.7 10.9 8.3 7.4 10.2 6.7 0.6 3.4 17.9 11.4 7.9 7.1 7.1 17.0 12.5 3.0 9.1 6.1 6.9 8.1 6.4 21.7 8.5 6.3 15.6 20.3 6.8 17.6 8.6 1.9 9.5 14.4 2.8 5.9 3.4 4.4 3.1 5.6 3.9 10.0 1.4 6.6 35.3 3.1 4.9 7.9 6.1 7.1 6.4 3.6 9.1 17.5 18.7 12.5 13.4 13.5 9.3 2.4 1.0 15.6 10.9 12.7 2.5 1.4 0.6 4.5 0.6 4.2 0.4 4.0 3.0 0.8 1.0 5.6 4.5 4.1 2.8 3.9 0.7 3.1 1.3 11.0 11.9 25.2 26.5 14.4 12.8 9.4 11.6 10.2 6.9 32.8 38.8 3.0 17.4 14.2 235.7 71.2 99.3 10.7 23.9 136.1 732.4 65.1 36.5 37.7 19.2 43.8 67.4 23.3 57.5 45.9 24.0 51.4 20.7 30.1 51.9 289.2 69.3 93.9 98.0 23.3 35.4 45.1 10.1 50.5 26.9 42.5 48.8 26.4 43.9 53.7 621.3 19.4 29.2 45.9 51.3 8.7 178.4 135.1 14.6 50.6 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81117295-81166077 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.3;intestine: 28.7" "Cell type enhanced" "Detected in many" 11 "Alveolar cells type 1: 29.8;Alveolar cells type 2: 23.6;Bipolar cells: 43.5;Horizontal cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "neutrophil: 3.6" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.6" "Group enriched" "Detected in some" 6 "CACO-2: 30.3;SH-SY5Y: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria NA NA Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 2.8 4.7 14.3 3.2 16.6 3.7 0.9 19.0 29.0 1.2 3.3 16.5 0.0 28.7 1.0 1.1 1.7 1.2 2.7 2.3 23.6 13.9 1.2 1.2 9.7 1.5 20.1 13.6 1.0 17.9 3.6 6.4 2.6 11.0 2.4 1.1 4.1 5.6 3.6 1.1 1.9 20.3 1.3 35.3 5.9 4.5 1.3 9.8 0.0 1.3 0.0 1.0 1.3 1.1 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 30.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.6 1.2 1.4 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 0.1 0.5 0.3 0.1 1.3 2.5 0.2 0.0 0.0 2.9 10.4 0.2 0.0 1.5 0.1 0.3 0.8 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 14.3 16.6 19.0 22.3 23.6 13.9 20.1 13.6 11.0 9.8 29.8 23.6 0.0 0.8 0.2 43.5 2.2 2.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.1 6.9 0.0 1.6 0.1 0.4 1.0 5.8 0.0 2.0 20.6 1.7 0.6 4.1 0.0 1.4 0.6 5.0 0.0 4.5 8.3 1.3 4.5 2.5 0.8 4.1 0.0 0.8 0.5 0.2 0.3 1.9 0.7 7.2 0.1 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 205.6" "Group enriched" "Detected in many" 25 "Early spermatids: 470.5;Late spermatids: 1015.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "memory B-cell: 3.7" "Group enriched" "Detected in many" 23 "B-cells: 3.7;monocytes: 2.0;T-cells: 1.9" "Group enriched" "Detected in some" 4 "ASC TERT1: 36.7;HUVEC TERT2: 18.7" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 92000000 Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 6.8 2.0 0.5 2.4 4.2 0.0 2.9 0.5 1.1 5.3 83.2 0.7 37.7 46.4 4.5 5.1 1.7 1.5 4.4 4.7 0.6 0.7 2.6 1.4 16.3 2.2 0.4 0.7 1.4 3.0 3.6 3.6 3.6 0.8 3.4 1.4 1.7 2.5 20.1 3.6 1.3 205.6 2.4 0.6 1.4 1.9 32.6 1.3 0.5 6.9 3.1 2.2 1.7 1.6 3.7 0.1 0.0 2.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 1.5 36.7 0.4 1.3 2.7 0.0 0.0 0.5 3.2 0.7 1.1 6.2 0.0 0.0 1.7 0.0 0.0 0.0 0.7 3.5 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.6 18.7 0.0 3.1 0.0 0.0 0.6 0.0 0.8 0.3 6.3 0.4 0.1 0.2 0.5 0.0 0.0 4.6 3.2 0.0 0.0 0.0 0.7 1.6 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.6 0.9 3.7 1.9 1.4 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.5 4.2 0.5 1.1 0.6 0.7 0.4 0.7 0.8 1.3 0.0 3.5 0.0 1.5 1.3 3.1 1.4 0.0 0.0 1.2 0.0 0.0 0.1 0.0 3.4 470.5 13.5 29.6 0.0 0.4 0.1 1.0 6.0 6.9 0.0 4.4 0.0 17.3 2.5 18.5 1015.1 4.0 5.1 3.3 0.0 8.7 1.9 0.7 10.2 2.5 10.7 1.0 0.0 0.9 8.1 3.4 0.1 0.1 0.9 8.6 2.1 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15561033-15602148 "Enzymes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 122.0" "Cell type enhanced" "Detected in many" 13 "Cholangiocytes: 61.1;Enterocytes: 38.8;Proximal tubular cells: 45.6;Sertoli cells: 19.4" "Cancer enhanced" "Detected in many" "renal cancer: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HaCaT: 4.1;Hep G2: 2.5;NB-4: 2.2;RPMI-8226: 2.1;RT4: 2.5;SH-SY5Y: 2.8;SuSa: 1.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" NA NA 85000 "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 4.5 0.4 0.2 0.8 0.2 0.0 2.3 0.2 0.2 0.4 49.1 0.2 2.3 46.0 0.4 2.7 1.2 0.6 16.4 10.5 0.2 0.1 23.2 1.2 0.8 0.6 0.2 0.2 1.3 1.6 0.0 0.2 1.0 0.2 0.5 1.3 0.2 1.1 1.2 0.7 0.2 122.0 0.3 0.2 0.2 0.5 17.9 0.2 0.2 4.5 0.5 0.2 0.4 0.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.4 0.0 0.7 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.4 4.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.2 0.0 0.0 2.1 0.4 2.5 0.6 2.8 0.1 0.3 0.2 1.9 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.3 2.2 0.5 0.1 0.0 9.8 61.1 0.0 0.0 0.0 0.0 2.9 3.3 0.5 0.4 0.0 38.8 0.0 0.7 0.2 0.0 0.4 0.0 0.8 0.7 0.0 6.9 0.0 0.0 1.1 7.8 0.0 0.0 0.0 1.2 0.0 0.9 4.2 5.6 45.6 0.0 19.4 0.0 1.1 0.7 0.1 10.6 0.0 3.3 1.6 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157875862 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 18.9 9.2 18.0 10.0 12.7 1.6 38.7 15.3 12.2 25.2 14.4 7.4 8.4 8.9 24.8 26.8 11.0 16.6 20.5 18.8 18.7 8.6 21.7 18.9 22.5 15.1 10.4 7.9 18.5 12.3 11.3 17.0 14.2 12.3 16.8 10.5 14.3 18.1 13.6 15.6 12.8 11.5 29.2 12.3 9.2 11.8 8.8 10.9 7.5 34.0 14.6 6.9 16.1 32.5 1.4 2.4 3.8 2.6 1.9 10.0 1.6 2.1 4.3 5.0 6.5 25.4 26.5 7.0 15.4 25.6 12.4 13.2 3.4 4.8 0.0 7.1 16.6 12.0 6.0 3.6 8.3 13.3 14.7 3.1 8.7 2.5 4.9 20.1 0.6 10.4 33.2 15.8 25.3 32.3 16.2 13.4 2.4 3.2 2.4 15.5 3.8 0.1 0.2 7.5 3.0 7.8 1.4 6.7 1.8 16.0 8.1 4.4 5.5 5.9 3.4 21.1 8.2 1.8 2.3 19.3 18.8 6.2 9.2 5.8 1.6 1.2 0.1 19.3 0.5 20.2 3.8 2.6 0.2 1.1 1.7 1.2 1.4 7.8 2.5 1.8 0.8 3.1 1.5 0.8 1.9 2.3 2.4 10.0 1.6 18.0 12.7 15.3 12.2 18.7 8.6 10.4 7.9 12.3 10.9 8.9 7.0 0.8 6.8 8.8 7.5 9.2 12.7 6.7 9.1 7.0 0.0 7.0 5.0 8.4 0.5 13.5 3.1 0.0 15.5 4.4 11.6 8.9 4.7 12.1 6.5 3.2 4.1 17.2 11.6 1.1 18.7 7.7 3.3 3.6 5.2 6.1 14.7 3.5 14.9 15.3 1.5 12.9 15.5 0.5 2.5 6.6 8.8 1.0 3.5 7.6 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951667-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 11.1 7.4 12.0 6.4 14.6 7.9 14.3 14.2 24.4 8.6 16.7 5.1 28.0 19.2 6.7 13.1 14.4 10.9 11.1 7.6 11.2 10.5 24.6 21.0 10.3 7.1 8.1 14.7 7.1 35.1 24.9 10.9 7.5 7.3 10.0 17.1 8.7 21.7 34.3 11.7 30.6 19.8 8.2 5.8 6.7 17.2 10.6 4.8 3.9 9.9 5.8 8.4 10.1 12.1 0.5 1.3 6.8 4.0 0.1 1.6 0.6 6.4 14.1 11.0 6.0 12.6 9.9 6.2 7.3 8.3 7.8 5.9 28.4 10.0 2.8 10.2 7.9 8.6 11.4 10.4 8.8 8.1 4.1 12.3 6.9 3.5 8.8 14.4 11.2 26.0 19.3 11.5 8.8 11.1 8.3 10.9 10.3 7.4 8.8 6.9 13.1 10.6 9.7 10.6 13.6 4.9 5.7 8.5 3.6 21.9 9.8 14.0 11.6 7.8 11.2 5.1 8.1 12.4 7.3 6.9 5.4 8.2 6.0 3.5 5.4 3.7 3.9 5.8 5.4 6.9 4.5 2.2 6.8 0.7 3.3 1.0 0.1 0.6 0.7 1.3 0.5 1.6 0.9 1.9 0.1 4.0 0.7 1.0 0.6 12.0 14.6 14.2 24.4 11.2 10.5 8.1 14.7 7.3 4.8 3.0 12.0 3.4 9.2 16.6 41.6 5.4 22.9 13.4 14.8 24.4 27.5 0.5 3.3 12.7 2.3 9.8 23.9 0.0 12.5 0.6 5.7 12.2 10.5 19.5 3.7 35.0 23.6 14.7 16.7 6.3 9.2 7.7 6.8 2.8 32.6 10.6 12.7 24.6 8.9 16.5 23.8 6.5 15.9 3.9 16.5 22.1 0.5 2.5 22.6 11.2 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157629005 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.2;breast: 15.3" "Cell type enhanced" "Detected in many" 12 "Enterocytes: 11.4;Leydig cells: 29.4;Paneth cells: 10.4;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.8" "Lineage enriched" "Detected in single" 4 "T-cells: 2.8" "Group enriched" "Detected in some" 4 "ASC diff: 15.4;HDLM-2: 6.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 29.2;cerebral cortex: 8.1;hippocampal formation: 21.6" "HPA007982, HPA011933" Approved "Intracellular and membrane" NA NA "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 36.2 3.7 3.9 2.7 10.3 0.7 15.3 1.6 4.4 0.9 9.4 2.7 0.0 5.5 0.7 1.0 0.8 0.8 1.8 1.0 9.2 3.1 1.1 3.3 0.8 1.2 3.7 3.1 5.1 2.4 0.5 12.0 0.7 3.5 0.9 4.4 0.0 1.5 1.0 1.3 0.7 4.4 0.8 2.8 0.8 3.4 1.1 4.0 0.0 0.9 0.5 1.0 0.6 2.9 0.6 0.0 0.0 0.0 0.0 2.8 0.4 2.0 0.0 0.0 0.2 15.4 0.5 0.3 0.4 0.4 0.1 0.5 2.3 0.2 0.0 0.2 1.2 1.0 0.0 0.1 0.0 0.3 6.8 1.0 0.0 0.0 0.5 0.0 0.0 1.2 0.2 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.3 0.0 0.0 1.4 0.1 0.7 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.3 0.0 0.3 0.0 0.8 0.2 0.0 0.2 0.8 2.4 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.5 0.0 1.0 0.6 1.8 1.2 0.0 0.5 2.8 1.1 0.0 0.0 0.0 0.0 0.0 0.4 3.9 10.3 1.6 4.4 9.2 3.1 3.7 3.1 3.5 4.0 0.0 0.6 0.0 0.9 0.6 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.2 1.1 1.0 11.4 0.0 0.2 0.3 1.2 0.8 0.0 4.7 0.1 0.0 7.5 0.0 0.0 0.4 29.4 0.0 3.3 7.2 8.4 1.0 0.4 10.4 8.5 0.7 0.0 0.0 1.0 0.0 2.0 1.3 0.2 0.0 12.1 0.4 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 21.0;RH-30: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 12.0 6.0 13.6 8.2 9.9 3.8 10.7 14.5 14.2 10.2 14.1 4.7 9.7 10.4 9.3 9.9 13.6 7.6 17.7 5.6 10.0 9.0 9.0 10.3 7.5 4.7 5.9 10.6 7.6 9.8 8.6 15.9 10.6 7.3 12.2 9.1 7.6 12.2 12.0 19.6 29.5 17.8 13.8 5.4 6.5 9.3 11.0 6.4 1.5 9.5 6.9 6.8 13.5 11.8 0.7 3.0 0.5 3.6 7.7 4.6 1.4 1.3 1.6 10.0 3.7 5.9 3.8 4.1 3.1 3.7 5.3 9.3 4.3 6.0 0.0 2.8 4.9 1.9 4.7 9.1 4.5 6.8 1.0 5.5 0.6 2.8 7.4 21.0 0.6 0.7 6.3 5.7 3.4 6.8 4.1 4.0 1.2 1.4 2.6 3.6 3.5 0.3 0.5 11.3 4.0 2.6 0.1 17.5 0.9 4.2 8.5 9.9 5.6 2.6 3.1 3.8 4.5 1.9 1.0 3.1 4.9 5.8 4.6 2.1 0.7 0.2 1.8 3.0 0.3 3.9 0.4 3.0 0.5 1.2 3.6 0.5 0.3 4.6 2.1 2.3 0.7 3.0 0.7 0.1 7.7 3.1 3.0 0.4 1.4 13.6 9.9 14.5 14.2 10.0 9.0 5.9 10.6 7.3 6.4 6.0 6.5 0.5 6.7 26.4 15.8 7.8 10.2 8.1 11.4 7.0 13.7 3.9 1.7 5.0 4.1 9.8 13.2 0.0 5.6 2.1 13.5 6.7 0.0 8.6 4.7 11.1 8.6 12.9 9.4 0.8 9.2 7.6 10.1 8.2 13.8 3.7 6.3 8.6 10.6 5.0 8.5 32.3 14.4 13.8 12.8 26.1 4.5 5.1 8.5 7.1 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453851-38493142 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 16.4;NTERA-2: 20.3;SuSa: 12.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007398, CAB025115, HPA040384" Approved Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" No No Cytosol "Nucleoplasm, Nuclear bodies" "CAB025115: , HPA007398: AB_2667822, HPA040384: AB_2732484" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 2.8 7.4 5.5 4.6 7.9 1.1 5.5 13.2 7.5 5.2 3.4 7.2 4.5 2.8 4.7 5.1 2.5 5.6 3.3 3.9 5.9 5.4 5.3 5.4 6.9 2.2 5.9 5.4 8.3 6.1 11.3 5.1 16.0 6.5 3.9 3.6 5.0 4.6 4.2 15.9 2.4 2.8 4.6 4.7 3.1 4.0 9.1 9.1 12.8 4.8 1.7 2.2 4.2 10.3 0.3 0.3 0.5 0.2 0.5 1.6 0.3 0.8 1.4 16.4 1.4 0.6 0.4 8.8 0.3 0.5 0.3 0.7 2.3 1.1 0.1 1.2 0.3 0.5 1.0 6.3 1.0 0.9 2.4 4.1 4.2 2.5 3.5 0.8 2.9 1.6 0.7 0.9 0.5 1.8 1.0 1.1 6.2 6.9 1.4 0.3 1.3 5.1 1.9 20.3 0.8 0.7 1.7 5.5 1.0 1.0 1.9 3.8 6.7 0.4 2.5 2.2 12.2 1.3 3.9 0.9 0.5 2.7 0.4 1.4 3.9 5.4 0.9 0.6 2.5 1.1 0.5 0.1 0.1 0.4 0.2 0.6 0.2 1.0 0.5 0.0 0.3 1.6 1.5 0.3 0.5 0.2 0.3 0.7 0.3 5.5 7.9 13.2 7.0 5.9 5.4 5.9 5.4 6.5 9.1 6.0 6.7 0.5 3.6 3.5 20.7 11.6 5.1 6.7 4.5 0.0 21.6 6.7 0.0 3.2 9.1 6.1 2.9 0.0 3.3 5.8 3.1 3.2 1.1 7.5 2.2 20.6 6.9 4.9 2.1 12.6 10.9 3.2 6.8 0.0 3.2 9.6 3.8 2.5 7.4 2.8 25.5 0.0 5.6 8.1 19.0 3.4 5.1 2.5 4.7 3.3 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.0" "Cell type enhanced" "Detected in many" 8 "Endothelial cells: 53.3;Enterocytes: 82.1;Ito cells: 40.5;Paneth cells: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 3.6;myeloid DC: 5.0" "Group enriched" "Detected in many" 12 "dendritic cells: 5.0;monocytes: 3.6" "Cell line enhanced" "Detected in some" "ASC diff: 18.5;ASC TERT1: 12.6;EFO-21: 16.4;HUVEC TERT2: 59.9;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 25.5 5.1 3.2 9.3 4.3 0.2 15.6 1.6 3.6 15.1 20.1 3.7 13.1 4.9 12.7 11.0 12.1 13.9 11.0 15.4 3.7 3.2 13.6 3.4 55.0 19.1 4.9 3.6 5.9 6.1 21.6 2.7 44.1 5.3 12.3 14.7 12.3 6.9 10.6 14.2 8.0 11.1 8.2 3.7 14.8 8.1 3.5 3.6 1.7 12.9 6.8 5.4 9.3 11.2 0.1 5.0 0.3 3.6 0.0 0.1 0.7 0.0 0.2 0.1 0.0 18.5 12.6 0.0 0.8 1.6 0.0 0.0 0.1 0.1 0.0 16.4 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 2.7 0.0 0.4 5.2 0.0 0.1 0.0 0.0 59.9 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.1 46.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.7 3.2 4.3 1.6 3.6 3.7 3.2 4.9 3.6 5.3 3.6 3.0 12.2 0.0 0.2 4.6 0.0 3.9 0.0 4.0 2.3 0.0 0.0 0.5 0.0 2.5 0.0 53.3 82.1 0.0 1.2 36.2 20.2 0.5 0.0 0.0 10.2 0.0 5.2 40.5 25.4 0.7 10.9 5.6 5.0 15.4 26.0 2.3 0.0 50.9 3.2 0.0 0.2 38.8 15.3 0.1 0.7 4.6 2.2 0.0 26.4 0.4 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430770-177442503 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 32.2;Karpas-707: 45.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" NA NA 28000000 "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (8.61e-4)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 12.8 15.1 11.2 11.2 11.9 10.9 18.5 4.4 13.7 13.5 12.1 24.2 8.0 8.0 9.8 26.4 18.8 7.1 15.1 8.4 13.0 9.4 20.5 26.5 12.4 12.3 14.0 11.0 10.2 14.7 19.2 9.0 9.3 15.0 10.1 11.1 24.0 27.1 10.8 6.7 16.9 14.4 8.1 22.3 14.9 13.0 13.3 10.0 13.4 14.0 14.3 18.3 9.0 10.2 10.0 11.1 16.3 23.8 8.9 16.3 10.3 2.1 4.7 5.4 7.7 6.4 5.7 3.7 15.8 32.2 8.2 10.4 2.5 10.6 10.5 2.9 12.2 4.0 2.6 4.6 5.2 16.7 6.8 3.0 4.4 5.2 6.9 4.2 7.6 3.0 4.0 9.1 6.0 2.7 7.4 7.7 4.7 3.9 45.6 3.3 5.8 6.1 4.8 2.1 4.2 4.9 1.9 2.2 1.6 8.7 5.3 3.0 6.9 4.7 4.1 12.5 4.3 9.3 15.7 2.4 5.7 5.1 2.7 6.1 8.8 6.7 5.6 9.2 8.7 6.4 15.0 10.7 16.3 11.7 18.9 13.4 10.0 12.8 14.0 10.5 8.1 11.4 16.3 2.4 8.9 23.8 11.1 12.0 10.3 11.2 11.9 4.4 13.7 13.0 9.4 14.0 11.0 15.0 10.0 11.9 9.1 12.3 14.9 21.3 3.3 5.7 17.8 5.3 11.4 14.0 2.0 21.6 5.0 21.9 11.4 11.1 9.1 0.0 27.5 25.3 15.5 15.7 13.9 15.1 21.7 6.4 5.2 6.2 9.1 6.8 10.3 22.8 37.1 25.2 16.6 17.6 20.6 5.8 9.2 16.3 3.7 0.0 12.4 34.8 31.5 23.8 19.0 22.3 13.4 15.2 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Cell line enhanced" "Detected in all" "MCF7: 115.3" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules NA NA Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favorable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favorable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.4 30.8 25.5 37.9 19.7 20.5 28.5 28.4 34.6 42.0 33.7 20.2 18.7 18.7 21.9 38.9 21.4 20.1 18.0 26.4 18.3 42.6 7.3 14.1 18.4 21.7 21.9 23.0 36.9 29.3 22.3 21.0 14.0 20.2 31.4 18.4 12.3 20.8 26.9 115.3 28.9 29.4 6.6 30.3 22.1 27.3 23.6 12.7 19.4 38.4 29.3 24.3 23.7 31.0 17.8 11.9 40.6 34.3 25.0 28.2 13.5 40.1 28.5 22.6 10.9 16.1 23.8 19.5 33.9 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 14.9 24.3 13.4 13.8 11.0 24.3 13.8 40.8 5.3 11.4 21.0 11.8 15.1 11.6 21.0 1.2 19.6 22.2 0.0 30.3 25.7 18.8 34.2 2.3 38.4 20.2 39.7 28.8 24.5 23.7 3.1 26.4 18.1 10.1 17.2 36.1 35.8 43.4 17.3 29.0 13.9 24.0 25.8 11.8 0.9 5.1 12.2 19.6 18.1 26.9 30.8 AKT2 ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 31.1 20.3 15.4 17.6 15.2 21.3 18.2 46.3 18.2 23.3 18.2 23.4 21.2 12.3 22.8 28.0 22.1 22.7 14.0 23.1 15.4 10.0 23.0 62.5 14.6 17.8 17.9 13.3 27.8 24.5 21.1 24.0 17.5 14.7 19.7 12.3 26.8 18.5 24.3 48.5 18.3 17.1 20.0 16.8 18.7 15.5 21.3 15.7 26.6 52.6 29.5 23.6 19.6 19.9 6.3 8.8 7.7 4.4 3.2 4.9 2.4 22.8 56.3 21.5 22.1 26.8 32.8 11.9 15.3 22.6 31.7 28.3 24.8 21.3 23.3 13.6 33.6 13.3 10.0 23.8 31.8 20.4 22.3 27.1 15.3 35.7 15.5 16.8 17.5 18.4 30.2 19.1 21.5 20.4 25.1 6.9 25.7 19.6 24.5 17.6 19.0 27.8 8.5 11.6 25.4 15.1 18.5 11.7 16.8 24.7 37.4 29.6 18.1 15.7 26.8 12.7 23.0 21.2 22.6 6.8 19.4 19.2 17.3 23.9 22.8 19.5 19.1 18.9 20.8 15.8 7.6 4.4 3.6 4.5 2.0 4.5 3.9 3.6 3.0 3.0 6.3 3.5 4.9 7.7 3.2 2.6 8.8 2.7 2.4 15.4 15.2 46.3 18.2 15.4 10.0 17.9 13.3 14.7 15.7 14.9 12.8 36.4 20.9 21.2 67.1 26.8 28.1 12.0 10.3 57.6 39.3 25.4 18.3 18.1 2.9 17.0 18.8 0.0 26.0 20.6 22.1 24.5 13.9 74.6 19.3 57.2 18.5 12.9 19.7 7.4 39.7 13.5 21.9 19.8 19.0 52.5 20.4 19.2 25.1 18.3 109.8 19.4 23.3 11.6 16.2 24.0 32.4 17.1 20.1 24.4 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol NA NA Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (9.27e-4)" 15.4 17.0 16.0 7.8 15.2 2.2 11.0 39.9 33.4 16.9 16.1 12.4 17.4 4.1 19.7 12.3 10.0 11.8 12.1 9.8 15.5 13.6 12.8 4.0 11.3 7.9 14.2 15.8 29.8 4.4 15.1 14.6 17.0 18.4 19.4 6.6 8.9 4.1 23.9 4.8 4.7 8.1 20.4 12.1 9.9 8.7 10.4 14.8 2.9 17.7 5.0 6.2 17.2 18.6 1.9 0.8 1.2 0.9 3.8 3.6 0.6 23.6 2.4 15.0 0.0 11.1 12.7 8.0 13.3 12.3 8.7 7.7 0.1 9.7 0.0 0.0 17.0 7.5 0.3 8.3 5.3 11.5 6.0 6.5 0.3 0.0 0.0 5.8 0.1 2.6 6.6 0.0 10.8 9.8 18.9 17.7 3.9 0.0 0.1 3.9 0.0 5.1 1.1 6.4 0.0 3.7 2.7 9.1 0.1 2.9 0.9 19.3 25.4 0.1 0.0 24.0 9.1 0.0 8.1 13.9 15.5 11.9 0.1 11.1 1.3 0.4 2.8 11.3 1.3 12.9 1.2 0.9 0.5 2.3 0.3 3.6 1.0 2.2 2.5 0.8 1.9 1.9 1.7 0.2 3.8 0.7 0.6 0.7 0.6 16.0 15.2 39.9 22.9 15.5 13.6 14.2 15.8 18.4 14.8 3.0 2.1 8.6 11.6 2.2 41.5 5.5 5.1 0.0 4.5 26.2 31.4 9.5 0.0 10.4 71.8 31.5 0.0 0.0 1.5 6.5 7.3 18.3 4.7 0.2 2.7 39.7 0.0 44.8 8.8 51.9 25.3 9.5 6.8 10.0 0.0 20.1 1.0 0.0 33.2 4.4 33.7 19.4 22.9 12.2 11.5 1.5 10.4 13.8 0.0 7.2 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605929-95656706 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 68.8" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 58.2;Paneth cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 23000 Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favorable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 6.3 10.4 7.1 10.4 7.9 5.2 7.7 7.3 9.3 13.7 20.1 7.2 20.5 33.8 9.3 12.3 12.8 8.5 15.2 7.2 6.2 7.1 13.0 28.9 6.6 7.4 6.7 5.3 14.5 40.7 12.7 17.4 14.3 7.7 9.6 19.4 7.9 68.8 20.5 3.5 9.6 45.4 10.0 5.4 8.6 15.2 8.4 5.4 12.7 25.9 9.7 15.9 8.6 8.2 13.1 5.2 0.3 4.0 13.0 16.3 8.0 18.3 17.4 16.8 44.0 22.6 21.8 18.1 21.5 32.3 21.9 27.6 34.9 14.7 62.6 20.1 33.8 10.6 24.4 33.6 22.1 24.9 17.7 26.4 19.8 12.4 49.5 14.8 34.6 22.2 22.9 13.6 17.8 34.9 36.4 22.9 23.6 18.5 13.2 16.3 26.4 31.2 22.3 19.8 30.5 17.4 29.4 19.2 21.4 25.5 14.0 16.8 16.6 17.1 13.6 15.8 20.1 20.3 16.2 18.9 9.1 14.5 23.4 24.6 15.3 11.3 38.3 17.7 40.1 11.6 0.0 1.4 0.1 15.5 2.7 16.3 13.1 14.2 16.0 5.2 9.0 12.1 13.4 0.3 13.0 4.0 3.1 13.3 8.0 7.1 7.9 7.3 9.3 6.2 7.1 6.7 5.3 7.7 5.4 6.0 8.6 11.5 6.6 10.0 5.7 4.3 10.2 16.0 14.8 19.2 0.0 36.1 1.7 12.5 0.7 5.4 58.2 0.0 18.4 25.8 17.5 15.6 8.1 23.1 10.1 9.5 19.0 4.9 3.2 0.4 8.6 3.1 15.1 2.8 37.5 5.2 12.4 54.7 11.3 7.9 2.8 0.0 5.6 5.1 9.0 7.0 25.3 8.7 30.7 8.1 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392664-38398661 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 113.9" "Group enriched" "Detected in many" 5 "Cholangiocytes: 117.2;Ductal cells: 60.1;Extravillous trophoblasts: 40.0;Hepatocytes: 113.4;Proximal tubular cells: 118.8;Undifferentiated cells: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 55.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA 210000 Mitochondria "Nucleoplasm, Vesicles, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 7.4 4.9 2.1 16.8 2.1 0.6 5.4 1.1 5.4 5.8 25.4 1.7 6.1 7.0 27.3 10.7 21.6 16.7 30.8 11.6 3.1 2.0 18.0 55.2 3.5 5.9 2.4 2.0 12.2 14.6 1.4 1.4 1.6 3.0 22.7 11.5 5.2 5.9 18.2 19.4 3.0 11.2 113.9 2.7 2.8 15.8 7.8 1.7 1.6 6.3 7.0 2.0 54.5 8.3 5.9 9.4 1.2 10.5 7.5 10.2 5.1 21.5 20.1 6.2 9.9 8.8 10.5 5.0 10.3 5.2 8.7 9.0 13.4 4.2 13.6 6.2 14.5 13.2 3.0 20.4 21.9 8.7 15.2 8.8 6.7 14.8 39.8 6.4 10.7 7.6 12.5 4.8 7.1 6.2 17.9 8.3 3.3 19.4 13.4 13.2 8.2 0.0 4.3 18.4 55.5 9.0 4.4 37.6 10.4 7.8 9.7 13.6 6.3 7.9 5.2 6.0 6.8 4.9 8.4 5.6 10.1 16.7 8.4 12.9 2.0 3.9 5.4 5.2 11.0 6.8 0.2 4.2 0.2 7.3 9.1 10.2 5.9 7.0 6.6 9.4 3.1 5.8 6.8 1.2 7.5 10.5 1.3 4.8 5.1 2.1 2.1 1.1 5.4 3.1 2.0 2.4 2.0 3.0 1.7 8.9 1.7 3.6 3.8 0.9 1.3 5.6 117.2 0.0 3.4 15.7 2.0 1.3 14.9 60.1 0.5 3.8 7.0 0.0 5.9 40.0 6.2 2.9 9.2 113.4 6.5 0.0 15.0 9.8 3.8 1.3 6.1 4.0 0.0 7.2 16.9 1.3 14.2 3.5 6.3 118.8 0.3 0.0 9.5 0.3 0.6 0.9 1.5 2.9 68.9 2.6 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family (mitochondrial)" P05091 12 111766887-111817529 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 279.7" "Cell type enhanced" "Detected in all" 9 "Hepatocytes: 770.8;monocytes: 1397.7;Proximal tubular cells: 645.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 45.8;myeloid DC: 46.6" "Group enriched" "Detected in many" 4 "dendritic cells: 46.6;monocytes: 45.8" "Cell line enhanced" "Detected in many" "ASC diff: 25.4;HHSteC: 28.4;OE19: 41.9;SK-BR-3: 57.1;THP-1: 25.4" HPA051065 Approved NA NA 1400000 "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 88.9 34.0 42.1 17.0 44.6 9.9 39.6 14.3 30.9 10.4 25.3 17.5 16.8 25.6 9.0 11.6 26.4 10.3 28.5 45.0 30.9 24.2 59.0 279.7 38.1 13.3 34.1 32.6 16.1 14.0 2.2 7.6 4.0 30.6 13.5 26.2 13.1 17.9 30.7 40.1 43.5 25.5 29.4 26.6 8.0 34.9 9.5 23.8 3.3 12.0 28.1 18.2 17.0 22.9 1.4 46.6 10.8 45.8 0.7 0.2 21.7 2.4 3.6 5.3 9.1 25.4 3.8 17.4 2.6 4.7 1.2 0.9 6.5 3.4 0.1 13.0 5.7 3.4 4.5 0.0 1.3 0.7 0.1 1.7 0.2 2.3 17.6 28.4 0.2 0.2 6.9 6.5 4.2 0.1 5.1 7.6 0.2 4.8 0.8 1.1 0.1 0.2 6.3 7.0 41.9 0.6 0.1 0.1 0.5 8.8 0.1 2.1 6.6 6.4 57.1 0.0 10.1 5.7 25.4 0.3 0.1 4.8 0.1 0.1 1.5 0.8 6.9 6.3 0.2 0.1 0.9 45.8 10.8 0.1 20.1 0.2 1.4 0.0 0.1 46.6 1.2 0.1 0.1 2.3 0.7 5.0 15.5 0.1 21.7 42.1 44.6 14.3 30.9 30.9 24.2 34.1 32.6 30.6 23.8 137.0 197.2 37.4 126.5 53.2 67.9 333.7 140.1 95.0 178.6 62.8 17.7 50.7 338.2 110.9 3.4 72.6 272.6 70.0 195.0 101.4 59.3 72.9 29.0 770.8 132.7 33.4 53.0 106.2 211.9 7.0 73.9 169.3 33.7 1397.7 184.2 107.6 110.7 325.4 140.0 645.3 34.9 45.3 77.3 2.7 3.2 109.0 35.2 13.8 218.4 82.3 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19677598 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease mutation, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 35.6;OE19: 66.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Approved NA NA "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 22.3 66.4 8.5 9.0 24.6 2.8 10.0 8.8 12.8 13.7 15.9 17.5 7.5 15.6 13.5 19.2 39.6 10.7 26.4 12.5 9.5 6.5 52.5 88.6 17.7 4.3 11.1 10.3 13.5 24.4 10.1 14.9 3.1 14.4 20.7 11.1 16.2 26.0 10.0 18.5 57.1 26.6 10.5 10.2 8.0 18.3 9.8 15.4 4.5 27.3 27.9 22.5 9.8 17.0 3.9 14.3 11.6 14.2 8.6 6.4 5.7 5.7 35.6 3.6 8.9 17.0 14.3 2.5 1.7 4.3 3.4 3.8 11.1 9.2 1.8 4.1 7.0 5.9 12.7 14.0 17.1 2.4 7.9 6.1 0.9 18.7 27.2 3.2 4.2 0.4 7.9 24.3 3.1 1.9 8.9 6.7 4.8 0.2 0.0 8.5 7.7 0.1 5.2 8.5 66.4 19.5 4.1 10.2 5.4 3.9 18.0 6.9 4.9 15.5 6.0 4.9 22.9 10.4 3.9 7.9 2.2 4.0 5.7 5.3 2.4 6.0 2.5 10.5 0.0 7.0 0.0 14.2 11.6 4.2 12.6 6.4 3.9 4.3 3.7 14.3 3.0 4.9 3.4 0.7 8.6 13.7 0.2 5.8 5.7 8.5 24.6 8.8 12.8 9.5 6.5 11.1 10.3 14.4 15.4 163.8 69.7 11.9 106.4 50.7 13.8 39.2 104.4 69.6 113.7 31.4 11.8 10.6 36.5 84.4 78.7 15.8 49.7 0.0 45.0 3.4 27.7 87.9 27.8 102.6 23.4 6.4 15.5 14.1 16.7 14.7 51.8 24.2 6.8 21.6 25.0 98.7 45.1 28.1 75.7 88.8 20.1 12.9 14.6 10.4 22.6 78.9 1.1 13.8 36.8 28.6 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595418 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.4" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 364.8;Proximal tubular cells: 241.4;Syncytiotrophoblasts: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 140000 Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 9.0 14.2 46.0 3.4 39.1 0.8 18.8 11.0 22.5 14.0 11.5 23.1 7.2 9.5 10.5 7.5 13.5 11.9 7.8 10.8 35.0 17.3 46.5 64.4 6.4 3.1 28.7 18.5 27.6 10.8 17.7 5.9 17.7 16.9 17.6 11.2 13.7 15.0 12.2 4.5 11.9 8.1 9.8 20.2 2.8 9.0 4.9 28.4 4.0 19.4 10.1 7.4 7.2 7.1 1.3 9.7 0.7 0.3 0.1 1.8 0.6 15.0 10.0 28.3 46.8 23.5 14.0 36.1 18.1 22.4 21.1 27.2 28.0 14.5 0.0 18.5 14.1 8.8 11.3 8.8 61.1 19.4 0.0 10.6 2.9 14.9 23.8 11.5 0.0 0.0 17.1 14.4 16.4 11.8 15.6 16.8 0.0 0.0 0.0 18.5 9.9 0.6 0.0 19.1 11.1 8.5 9.0 32.1 0.0 20.0 11.5 9.6 11.5 0.0 10.0 10.5 22.7 18.0 0.6 20.4 6.1 18.9 7.0 12.4 0.0 0.0 0.0 3.3 0.0 9.8 0.7 0.3 0.1 0.2 0.0 0.3 1.3 0.3 0.2 2.7 1.1 1.8 1.0 0.3 0.1 0.0 9.7 0.1 0.6 46.0 39.1 11.0 22.5 35.0 17.3 28.7 18.5 16.9 28.4 14.9 24.0 11.8 48.6 23.0 22.4 35.5 25.5 20.1 33.0 40.1 21.6 364.8 64.6 31.9 24.9 14.7 17.8 0.0 12.1 88.6 30.8 28.6 6.9 69.5 42.5 23.8 20.8 20.9 9.4 29.5 23.6 7.4 52.3 12.6 22.1 96.8 15.1 8.6 35.0 241.4 12.2 19.4 17.3 1.0 3.1 14.1 185.9 2.5 43.7 34.8 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Muller glia cells: 289.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 1100000 Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 39.1 52.7 30.8 17.4 25.4 7.7 39.6 16.2 26.6 20.3 18.0 22.7 17.1 19.5 15.5 35.5 47.0 18.8 22.2 22.2 24.8 21.1 50.5 73.5 20.7 20.4 23.7 18.4 20.6 17.8 31.2 19.2 14.1 22.8 24.6 18.7 27.2 52.2 23.2 29.9 22.6 23.9 19.2 21.9 18.8 14.7 37.3 21.5 12.4 45.1 24.2 27.9 18.5 19.1 29.6 20.2 29.4 24.5 23.1 39.0 24.4 17.0 16.7 15.6 14.0 49.9 44.0 13.1 22.6 32.1 22.8 19.8 10.3 12.8 0.0 21.7 20.2 11.2 13.5 12.6 22.1 27.0 7.9 16.0 10.9 12.0 11.2 25.7 17.0 11.6 28.2 11.2 24.1 20.2 31.6 19.7 14.5 17.2 15.4 35.4 10.2 11.3 17.6 22.7 44.9 20.5 9.7 19.8 22.8 29.6 16.2 18.6 12.8 16.1 18.2 20.7 22.1 34.6 25.9 19.4 13.8 13.5 16.7 11.4 14.4 18.7 17.0 15.5 16.3 13.2 26.8 20.3 28.1 28.3 21.5 30.1 29.6 27.7 30.6 20.2 26.0 28.1 32.0 29.4 23.1 24.5 12.6 39.0 24.4 30.8 25.4 16.2 26.6 24.8 21.1 23.7 18.4 22.8 21.5 14.9 37.5 27.9 34.1 29.0 24.6 38.9 48.4 69.6 30.7 48.8 21.6 42.9 82.9 36.4 32.5 37.9 44.4 23.3 32.5 64.2 46.7 49.5 36.9 114.6 53.7 12.7 53.6 52.8 58.2 28.9 88.3 37.5 54.0 19.8 52.5 289.8 28.8 31.6 108.5 141.7 26.8 25.8 36.0 33.8 46.2 45.4 31.9 38.9 58.1 23.5 AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425538 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 124.0;Hepatocytes: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: AB_2672869, HPA077835: AB_2686856" "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (2.43e-2)" "unprognostic (3.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (4.16e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" 13.9 25.9 21.3 10.6 23.8 14.1 28.7 12.6 25.0 17.2 21.0 24.5 18.5 21.6 16.6 25.2 20.8 15.3 13.7 17.6 20.6 20.2 35.2 50.0 13.3 19.3 22.3 14.3 20.5 14.0 33.3 13.0 41.6 18.9 14.9 11.8 23.8 12.6 18.6 71.6 11.9 18.8 16.0 25.0 14.3 12.2 36.8 17.5 14.6 18.6 10.1 19.3 15.5 16.9 18.3 10.6 21.4 13.1 11.7 9.7 4.0 17.7 24.8 10.8 19.9 33.9 19.1 9.5 19.2 23.8 26.1 20.5 22.0 16.9 46.3 22.2 25.9 15.4 16.6 16.6 14.9 24.9 10.3 17.0 14.0 10.2 23.6 29.7 10.8 16.2 22.1 21.7 20.8 24.9 18.5 15.2 13.6 14.5 6.4 18.9 11.2 16.2 11.6 5.1 9.2 17.0 18.4 21.9 17.4 16.1 18.6 10.9 8.3 45.1 15.8 14.5 11.1 47.6 11.4 19.6 24.6 13.5 12.4 12.9 13.8 12.1 24.6 17.9 7.9 11.2 21.4 8.5 10.9 6.9 9.9 9.7 18.3 8.7 7.1 7.8 15.6 9.1 9.5 10.5 11.7 13.1 10.6 9.0 4.0 21.3 23.8 12.6 25.0 20.6 20.2 22.3 14.3 18.9 17.5 8.9 7.0 28.6 15.3 22.9 17.3 18.2 30.6 1.4 9.1 94.2 37.3 20.9 21.6 18.1 124.0 20.4 37.5 0.0 37.1 5.8 28.2 27.6 8.1 146.0 15.4 30.2 23.8 39.3 62.3 81.3 38.0 22.3 28.7 15.4 25.9 45.2 27.4 21.0 32.2 42.8 41.0 12.9 26.9 32.0 10.8 18.2 20.4 15.2 19.8 17.2 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 27.1;ovary: 38.2;testis: 15.2" "Group enriched" "Detected in some" 4 "granulocytes: 25.4;Ito cells: 12.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "HEL: 28.3;K-562: 15.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "hippocampal formation: 14.3" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.3 27.1 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.0 0.3 0.6 0.4 0.2 0.4 0.8 0.2 0.0 0.2 1.1 0.3 0.2 0.2 0.2 38.2 8.8 0.1 0.2 0.2 0.3 0.4 0.0 0.2 0.2 0.2 2.5 0.0 0.4 0.5 0.2 3.7 0.3 15.2 0.2 0.2 0.2 0.5 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 28.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 2.4 0.0 0.0 0.0 1.8 0.0 0.0 0.1 25.4 0.0 0.1 0.0 0.0 12.3 2.2 1.3 4.6 0.0 0.0 0.0 0.0 0.0 4.6 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.0 0.0 0.0 ANKRD1 "ALRP, C-193, CARP, CVARP, MCARP" ENSG00000148677 "Ankyrin repeat domain 1" Q15327 10 90912096-90921276 "Disease related genes, Predicted intracellular proteins" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 81 "heart muscle: 398.9;skeletal muscle: 333.3" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 12578.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "EFO-21: 104.9;hTERT-RPE1: 57.1;LHCN-M2: 128.8;SuSa: 41.0;TIME: 179.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA038736 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Nucleoli fibrillar center" Nucleoplasm "HPA038736: AB_2676184" "unprognostic (2.45e-1)" "unprognostic (6.14e-3)" "unprognostic (2.24e-1)" "unprognostic (4.39e-1)" "unprognostic (9.14e-3)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.28e-2)" "unprognostic (6.63e-3)" "unprognostic (2.19e-1)" "unprognostic (3.27e-1)" "unprognostic (4.51e-2)" "unprognostic (3.40e-1)" "unprognostic (2.72e-5)" "unprognostic (3.40e-2)" "unprognostic (2.79e-1)" "unprognostic (7.22e-2)" "unprognostic (3.16e-3)" 1.5 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.1 1.5 0.1 0.1 398.9 0.0 0.0 0.1 0.1 4.5 0.2 0.0 0.0 0.1 0.4 0.1 0.1 0.7 0.1 0.9 0.1 0.0 0.8 0.1 333.3 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 2.9 1.6 0.5 0.3 0.0 0.4 0.5 1.9 0.6 0.9 0.4 0.2 2.9 0.8 0.5 0.0 0.4 0.5 0.0 1.7 0.1 0.5 0.9 38.0 1.4 0.0 104.9 0.1 4.0 1.0 0.1 0.2 1.3 0.1 0.1 0.0 0.2 11.7 2.3 0.0 0.0 3.7 0.0 0.7 1.8 57.1 35.8 0.0 0.0 0.0 128.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 8.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 41.0 0.0 0.1 179.4 0.3 13.8 0.2 14.1 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.2 0.5 0.2 0.3 0.3 0.3 0.2 0.2 0.2 0.4 0.4 0.3 0.7 0.9 0.6 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 848.6 37.7 0.0 1.3 0.0 0.0 12578.5 10.2 1.4 9.1 0.0 0.0 0.1 0.0 19.0 2.0 0.0 0.0 0.0 0.2 0.2 0.2 0.4 3.5 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551519-78610451 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 83.0" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 1: 547.9;Ductal cells: 468.5;Exocrine glandular cells: 274.5;Pancreatic endocrine cells: 473.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 319 "neutrophil: 51.3" "Lineage enriched" "Detected in single" 319 "granulocytes: 51.3" "Cell line enhanced" "Detected in many" "A-431: 51.5;CACO-2: 52.8;CAPAN-2: 71.5;EFO-21: 43.8;hTERT-HME1: 72.9;OE19: 61.8;RPTEC TERT1: 61.4" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Enhanced "Plasma membrane" NA NA 7400000 "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 20.3 1.1 4.0 7.1 7.4 83.0 16.2 2.4 6.8 7.0 8.5 2.3 0.9 4.2 3.4 4.2 25.0 4.6 11.7 20.5 5.2 5.2 19.8 1.6 46.0 5.7 6.6 5.6 2.8 14.7 6.5 5.8 33.7 10.4 18.8 7.4 2.6 50.8 3.6 14.2 4.1 9.3 5.3 4.0 11.0 23.4 1.8 5.0 2.0 45.3 13.6 7.4 2.8 5.9 0.1 0.0 51.3 0.1 0.0 0.0 0.5 51.5 9.8 0.1 0.1 0.1 0.2 0.0 0.6 0.0 1.5 1.4 52.8 71.5 0.0 43.8 1.8 0.0 20.4 0.0 37.7 2.3 0.2 0.4 4.6 21.1 3.1 6.1 0.6 0.0 0.3 33.4 0.5 72.9 7.6 14.9 1.2 0.1 0.0 0.2 2.0 0.2 0.0 1.6 61.8 7.2 0.0 0.1 0.0 61.4 5.9 0.0 0.0 30.4 7.5 2.1 25.3 1.3 0.6 18.9 0.1 6.8 0.0 11.6 0.4 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 51.3 0.0 0.1 0.0 0.0 0.5 4.0 7.4 2.4 6.8 5.2 5.2 6.6 5.6 10.4 5.0 547.9 38.9 0.0 51.1 22.0 0.0 6.4 58.6 36.1 144.5 36.6 0.0 172.1 14.9 468.5 0.9 32.1 19.7 0.0 274.5 87.0 24.3 117.9 4.7 0.4 16.1 0.0 5.2 20.3 0.0 0.0 2.8 1.7 5.0 36.1 30.9 0.8 473.1 58.5 0.4 1.1 0.3 0.0 9.5 1.2 0.7 5.8 52.5 0.5 28.7 32.0 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512949-36724549 "Enzymes, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 54.6;lymphoid tissue: 57.4" "Cell type enhanced" "Detected in many" 17 "Hofbauer cells: 31.1;Kupffer cells: 110.3;Macrophages: 54.2;T-cells: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "classical monocyte: 54.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 4.1;NB-4: 21.3;THP-1: 16.3;U-937: 7.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 8.4 3.4 5.2 17.2 4.9 19.3 2.8 1.9 3.6 3.1 5.3 7.4 0.2 4.9 3.9 7.2 2.5 3.1 8.4 3.4 4.8 3.8 3.1 6.8 9.4 23.2 6.9 2.0 2.1 2.3 0.6 2.4 5.7 5.8 3.8 7.3 3.8 4.5 1.4 1.5 1.6 7.6 4.7 12.6 57.4 3.3 1.4 6.8 14.0 2.9 0.4 10.9 7.2 2.8 0.3 34.8 18.7 54.6 19.2 8.8 31.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.5 0.0 0.0 0.0 2.9 0.0 0.3 0.1 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 21.3 0.1 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 0.3 54.6 17.6 8.8 47.9 1.8 0.3 0.4 6.1 34.8 0.0 1.0 7.8 18.7 19.2 20.2 0.5 0.1 31.0 5.2 4.9 1.9 3.6 4.8 3.8 6.9 2.0 5.8 6.8 0.0 14.0 8.8 0.0 0.7 0.0 0.4 0.0 1.4 4.5 0.0 0.0 0.2 1.7 0.2 0.4 0.5 5.8 0.0 0.0 0.2 0.5 0.1 4.7 0.6 31.1 0.0 14.9 3.1 110.3 0.4 0.0 54.2 0.0 19.0 0.4 3.2 0.0 1.5 0.4 0.3 0.2 0.0 0.9 0.0 0.0 0.3 0.1 51.7 0.5 0.1 AOC1 "ABP1, DAO" ENSG00000002726 "Amine oxidase, copper containing 1" P19801 7 150824627-150861504 "Enzymes, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.6;placenta: 240.4" "Cell type enhanced" "Detected in many" 19 "Collecting duct cells: 258.2;Enterocytes: 648.3;Paneth cells: 375.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "eosinophil: 20.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 20.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.4;HaCaT: 5.0;NB-4: 5.0;RPMI-8226: 6.0;THP-1: 21.4" "Not detected" "Not detected" "HPA031032, HPA031033" Approved "Secreted in other tissues" NA NA 800000 "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" 0.3 0.3 0.3 6.7 0.3 0.0 0.3 0.3 0.3 0.9 68.3 0.2 1.2 30.2 0.3 3.9 1.7 0.3 4.4 0.3 0.3 0.3 37.9 1.5 0.3 0.6 0.3 0.1 0.3 0.6 0.0 0.3 240.4 0.1 1.3 15.5 0.1 0.4 0.2 0.3 0.8 108.6 0.2 0.3 0.4 2.7 1.8 0.1 0.7 0.3 0.1 1.0 0.4 0.4 0.0 1.0 20.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 2.5 16.4 0.0 2.2 0.0 1.4 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.1 5.0 0.2 1.5 0.0 0.0 0.0 6.0 0.2 0.1 1.8 2.1 0.0 0.7 0.0 0.3 0.6 21.4 0.5 0.2 0.1 0.5 0.0 0.2 0.1 0.1 0.1 0.8 0.0 0.1 0.1 20.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 1.2 258.2 0.0 1.1 13.3 0.0 5.7 0.0 648.3 0.0 3.0 3.0 0.2 0.9 5.7 0.0 2.8 0.0 41.6 0.0 0.0 8.4 0.0 1.3 0.0 115.4 108.6 0.0 2.2 375.2 0.0 73.1 0.0 0.0 0.1 2.8 0.7 0.1 2.9 0.0 80.4 0.3 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase, copper containing 2" O75106 17 42844600-42850707 "Enzymes, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 133.5" "Cell type enriched" "Detected in some" 9 "Early spermatids: 28.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 4 "neutrophil: 4.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 14.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA057779 Uncertain "Intracellular and membrane" NA NA "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.47e-4)" 11.6 1.2 0.9 1.3 3.2 1.8 3.1 3.2 1.6 1.5 1.1 0.9 0.9 0.6 1.5 1.2 1.0 1.5 1.5 1.3 1.2 1.8 0.9 3.6 2.2 1.0 0.9 0.9 1.0 1.2 0.8 2.1 0.9 0.9 1.3 0.5 133.5 1.2 1.2 1.4 1.2 1.0 1.3 1.0 1.7 0.7 6.5 0.9 1.0 1.0 0.9 1.2 1.6 0.9 0.1 0.0 4.0 0.0 0.0 0.6 0.0 0.2 2.8 0.6 3.1 14.3 1.4 7.4 0.9 0.9 2.0 2.8 2.2 0.3 1.1 1.4 0.3 0.9 1.2 2.7 0.7 4.1 2.3 7.3 0.4 1.3 2.2 0.9 0.4 2.8 2.2 2.5 1.9 2.9 0.4 0.5 3.8 0.7 2.6 0.6 0.3 0.6 1.1 1.1 0.3 0.9 1.4 2.9 2.3 0.4 4.4 1.0 0.6 0.1 1.0 4.0 6.0 0.5 0.2 0.5 1.9 4.1 2.5 1.2 5.7 5.6 1.1 0.5 2.6 1.0 0.0 0.0 0.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.9 3.2 3.2 1.6 1.2 1.8 0.9 0.9 0.9 0.9 0.0 0.3 0.0 0.5 0.9 0.2 0.3 0.0 0.0 1.2 0.0 2.0 0.1 0.0 0.4 28.8 0.7 0.0 0.0 0.3 0.1 0.2 0.7 0.0 0.8 0.1 0.0 0.0 0.6 0.8 3.3 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.2 0.6 0.0 0.9 2.1 2.7 1.4 0.0 0.0 0.0 0.5 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase, copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 19 "Peritubular cells: 70.4;Sertoli cells: 116.4;Smooth muscle cells: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 13 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Cell line enriched" "Detected in some" 18 "ASC diff: 85.5" "Low region specificity" "Detected in many" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 97.0 11.5 0.4 18.7 1.0 0.0 67.7 0.5 1.3 26.9 44.3 1.0 16.3 3.6 44.7 34.8 36.1 18.5 50.9 12.1 0.4 0.4 5.8 8.3 48.0 7.9 0.5 1.2 23.8 2.4 2.2 1.3 10.8 2.0 36.5 9.4 32.1 8.0 24.7 7.7 5.5 15.0 79.2 0.6 7.5 17.7 16.2 0.3 1.0 6.6 11.6 2.6 75.9 20.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 85.5 0.1 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.3 1.5 0.1 0.1 4.7 0.2 0.0 0.2 0.9 0.2 0.1 0.2 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.7 0.0 0.5 0.0 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.7 0.3 0.1 1.2 1.4 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.5 1.3 0.4 0.4 0.5 1.2 2.0 0.3 3.0 8.9 0.8 0.0 2.6 0.0 3.2 0.0 1.4 3.4 0.0 0.0 0.1 0.0 0.1 3.8 4.7 0.0 0.0 0.2 0.1 2.6 0.2 1.1 0.0 1.1 0.0 0.0 22.7 3.0 2.1 3.1 0.5 3.3 0.0 0.0 0.4 0.1 0.0 70.4 0.7 0.5 116.4 56.5 0.9 0.7 1.6 0.2 0.0 0.0 0.3 AP000812.4 ENSG00000284844 11 72105924-72109329 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.1;cervix, uterine: 1.1;testis: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.4;RH-30: 1.2;SK-MEL-30: 2.9;WM-115: 1.1" NA NA 0.0 0.0 0.0 1.1 0.0 0.9 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.5 0.5 0.0 0.0 0.0 0.9 0.5 0.2 0.1 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561100-47571920 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046188, HPA066326" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" Nucleoplasm "HPA046188: AB_2679578, HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 22.2 24.2 10.9 16.5 15.5 41.9 19.5 16.0 13.7 18.0 23.2 21.1 24.1 17.8 21.3 18.4 19.4 18.7 21.0 28.6 12.8 7.3 28.0 49.6 21.8 20.2 16.4 9.5 23.4 35.1 28.1 16.9 25.3 13.5 23.5 15.8 25.4 22.1 18.5 60.8 18.9 23.8 18.6 11.2 27.4 24.2 10.2 16.3 27.7 23.1 23.9 27.3 20.2 16.9 23.9 34.3 36.1 38.4 22.4 29.1 27.5 20.3 29.3 12.6 20.2 19.2 15.3 17.0 17.2 18.2 25.7 23.7 23.9 25.0 12.1 14.1 23.0 21.6 28.7 22.2 23.7 14.8 22.3 26.1 12.1 31.1 12.3 27.0 24.0 37.2 20.1 24.2 24.5 21.5 17.0 19.7 15.4 22.5 23.9 17.4 34.4 17.4 25.9 18.1 17.2 32.8 16.2 16.4 27.3 14.7 19.5 14.3 11.0 18.5 17.1 10.1 20.8 32.2 18.2 18.7 16.7 18.8 33.3 17.3 31.0 19.8 9.4 22.2 27.2 13.3 23.9 29.0 36.1 29.1 35.4 26.9 21.4 25.5 26.7 34.3 23.9 22.7 26.7 23.6 22.4 38.4 24.7 25.1 27.5 10.9 15.5 16.0 13.7 12.8 7.3 16.4 9.5 13.5 16.3 14.9 36.4 18.8 19.6 14.0 4.0 23.6 30.6 8.1 10.3 17.4 9.8 27.3 19.9 24.2 1.1 17.9 37.6 0.0 29.9 25.3 15.5 19.0 16.1 35.8 24.8 12.7 30.5 22.7 22.7 3.0 16.1 21.7 32.1 55.1 36.8 13.3 23.6 40.2 16.6 22.1 8.2 19.4 18.6 5.6 10.2 14.2 37.3 27.4 26.6 21.6 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869516-102901899 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 92.8;parathyroid gland: 30.0" "Cell type enhanced" "Detected in single" 20 "Club cells: 1.2" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "NK-cell: 1.4" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.4" "Cell line enhanced" "Detected in many" "AF22: 14.3;REH: 27.2;SH-SY5Y: 14.6;T-47d: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria NA NA Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 2.0 92.8 3.7 0.7 8.6 0.5 2.6 4.5 6.4 4.0 2.0 2.2 0.4 1.3 3.8 3.2 2.1 2.1 5.2 10.0 5.7 3.1 7.4 22.4 1.7 0.9 2.8 4.4 3.9 8.7 30.0 2.4 0.5 4.6 4.2 0.8 8.9 2.2 3.4 6.0 1.8 1.3 3.9 2.7 5.6 1.7 3.5 1.6 0.3 3.2 1.0 0.7 1.8 1.8 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 3.9 14.3 8.9 0.3 0.3 2.6 4.1 3.5 6.2 7.6 10.6 0.6 0.2 1.2 5.4 0.3 0.2 12.1 0.7 6.4 0.0 3.5 0.0 1.7 10.4 4.1 0.2 0.1 1.9 1.6 0.8 0.0 11.2 0.2 13.2 0.0 0.2 5.5 0.1 2.4 0.3 6.8 0.0 0.6 27.2 0.0 0.1 1.3 0.1 0.4 14.6 0.0 0.2 1.9 4.9 22.7 0.3 0.1 1.3 0.0 2.0 0.0 0.3 0.2 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.7 8.6 4.5 6.4 5.7 3.1 2.8 4.4 4.6 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Muller glia cells: 462.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 900000 "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" 104.6 60.4 27.3 15.0 29.5 4.8 84.3 35.2 31.3 22.3 23.8 10.6 18.3 14.0 16.8 17.8 22.4 16.5 19.1 33.9 26.1 22.4 19.0 23.0 22.5 10.9 21.1 22.2 20.5 13.8 12.5 15.7 14.7 20.5 17.3 26.8 23.6 28.8 23.4 103.1 12.0 13.9 26.1 16.7 12.8 30.5 6.4 19.6 2.9 31.7 36.0 13.7 30.0 25.4 3.3 21.0 15.9 5.2 4.9 3.4 2.3 49.9 72.6 10.2 6.2 45.7 43.5 3.5 89.7 83.3 38.4 40.3 12.4 66.6 3.8 6.2 52.5 30.9 18.7 6.3 31.3 65.7 1.4 6.4 8.9 44.1 33.9 29.3 1.3 1.4 35.7 7.0 21.3 27.3 75.4 16.2 2.0 2.4 3.6 33.8 10.6 0.3 1.8 5.8 48.4 42.8 2.4 11.0 0.8 23.4 41.4 10.6 3.6 27.8 13.1 11.1 5.8 5.3 2.4 50.8 38.9 20.0 35.5 31.6 2.3 2.9 0.1 102.4 0.8 26.0 1.1 5.2 0.1 1.6 1.9 3.1 3.3 2.3 1.6 6.1 3.3 3.4 1.6 15.9 4.9 1.0 21.0 2.3 2.3 27.3 29.5 35.2 31.3 26.1 22.4 21.1 22.2 20.5 19.6 181.7 183.4 8.3 108.3 41.8 126.7 192.2 22.9 57.6 137.6 82.0 276.9 97.4 13.3 97.2 1.6 71.6 39.8 0.0 158.3 85.9 64.5 113.1 8.1 51.6 62.4 120.8 111.8 38.6 25.4 0.5 65.6 43.4 40.5 13.6 178.8 462.0 186.9 24.6 54.1 31.9 150.0 45.3 73.9 2.6 16.8 44.0 40.2 10.0 58.7 212.3 ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121740421-121928801 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cardiomyocytes: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA038444: AB_10672745, HPA057549: AB_2683463" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-3)" "unprognostic (2.40e-1)" "unprognostic (4.67e-2)" "unprognostic (6.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.20e-1)" "unprognostic (8.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" 15.4 16.9 14.6 16.8 18.8 14.7 16.9 23.1 20.8 17.4 18.8 17.6 12.6 13.5 14.4 14.3 15.7 13.6 14.4 27.5 15.0 18.4 23.1 23.0 14.0 11.7 17.6 14.0 14.4 13.4 23.6 22.5 15.0 15.4 16.5 20.0 19.0 14.1 16.6 33.6 12.0 16.2 25.8 15.6 12.9 12.0 18.1 14.6 21.4 22.0 11.2 14.3 22.8 15.2 14.0 14.4 17.1 11.5 9.9 16.0 8.5 10.0 17.1 13.3 11.2 9.2 11.0 9.1 8.8 15.9 10.6 11.2 22.2 12.5 12.4 7.3 10.1 7.1 10.3 12.3 8.8 10.3 20.4 10.9 4.4 7.5 17.9 9.4 18.9 10.4 8.0 8.2 11.0 23.3 12.5 11.5 8.2 6.8 25.7 8.4 6.3 10.2 7.8 6.8 10.9 8.2 10.0 14.0 7.2 13.4 8.6 3.8 12.4 12.0 8.5 18.2 8.9 6.2 4.8 14.1 6.1 6.0 9.1 15.7 22.4 30.8 15.1 9.5 13.2 5.1 17.1 11.1 14.7 16.0 11.1 15.5 13.0 13.9 13.7 9.4 14.0 15.7 14.3 8.1 9.9 11.5 14.4 13.6 8.5 14.6 18.8 23.1 20.8 15.0 18.4 17.6 14.0 15.4 14.6 8.9 15.8 7.4 11.5 7.4 21.9 62.1 7.6 12.0 14.8 19.2 11.8 6.1 14.9 9.2 5.3 13.6 18.8 0.0 11.6 8.0 10.8 18.1 11.6 23.8 8.5 22.3 21.2 26.4 14.8 5.8 19.0 10.5 13.5 6.4 14.8 18.4 12.5 14.4 24.4 29.3 31.4 0.0 11.7 23.5 33.8 15.3 7.2 10.4 15.0 14.6 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 198.3;Rod photoreceptor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.7 3.9 7.7 4.1 10.0 14.6 2.0 6.1 6.8 3.5 5.9 4.8 6.5 9.6 9.1 4.9 5.6 4.1 5.8 5.1 5.5 7.7 3.4 8.7 4.8 4.8 5.3 10.5 9.4 9.4 3.2 5.4 10.4 7.7 7.4 8.2 8.4 6.6 6.9 2.0 7.1 9.7 6.3 4.1 3.9 5.6 5.3 15.1 4.0 5.5 5.2 6.4 7.1 3.3 10.5 7.1 5.0 5.9 11.5 8.8 4.9 5.0 5.7 4.4 4.6 48.5 5.8 11.5 9.8 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 35.7 21.0 122.7 17.4 11.2 101.7 35.4 10.2 13.4 19.4 21.0 198.3 14.8 5.0 7.7 12.8 18.8 4.9 0.0 10.6 10.5 26.4 9.5 12.7 21.2 26.0 57.2 19.5 36.8 82.2 2.7 36.5 48.1 25.3 9.0 15.9 35.9 7.6 10.5 26.2 10.3 196.6 25.8 17.3 18.7 33.6 10.8 3.5 111.7 11.7 9.9 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449235-142578826 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 35.3;Spermatocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 10.5 24.3 7.7 11.4 15.9 10.1 14.8 11.3 14.6 10.1 8.5 10.0 10.4 6.0 14.7 16.8 9.4 12.1 9.3 8.8 9.8 7.1 9.6 12.0 10.3 16.0 10.0 8.1 12.3 13.6 18.0 22.5 8.8 12.5 11.0 11.2 9.5 12.5 10.8 7.7 11.2 10.9 9.8 8.8 14.2 9.0 15.3 9.7 19.0 13.8 7.7 15.1 10.9 10.6 5.8 2.8 2.2 4.0 6.7 6.0 0.8 22.7 11.2 7.5 8.5 10.7 11.8 8.9 12.6 7.1 9.4 9.7 5.2 7.3 18.6 13.0 8.9 12.3 14.8 11.0 11.6 14.2 5.9 7.2 10.2 8.5 5.1 4.7 17.1 5.7 9.2 6.4 8.9 10.6 6.4 9.7 9.7 7.1 8.4 9.6 10.0 12.9 7.1 7.2 14.9 8.0 10.7 10.9 13.5 9.5 10.6 5.3 5.4 23.2 8.4 8.2 7.1 12.2 6.9 12.5 9.6 4.8 12.4 13.5 11.0 6.5 17.3 12.5 6.7 7.6 0.7 2.7 2.2 4.4 4.0 6.0 3.1 3.2 4.2 2.8 5.8 4.1 4.0 1.7 6.7 2.5 2.5 2.4 0.8 7.7 15.9 11.3 14.6 9.8 7.1 10.0 8.1 12.5 9.7 6.0 8.8 13.4 6.5 3.5 14.7 7.1 7.6 18.7 6.8 3.5 35.3 6.6 0.0 5.3 12.0 7.1 2.1 0.0 4.3 3.3 4.8 6.7 1.1 6.0 5.7 7.9 7.5 8.6 9.1 6.9 6.1 6.9 10.1 4.6 5.4 4.8 6.2 0.0 6.7 4.1 23.4 0.0 6.4 42.3 15.8 4.0 4.2 5.1 7.0 5.2 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361913 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Distal tubular cells: 162.5;Proximal tubular cells: 92.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 13.0 39.6 14.3 15.6 20.1 3.8 15.2 22.5 20.7 14.1 19.8 10.5 25.3 19.2 11.1 16.0 8.9 10.7 11.4 30.4 15.4 19.7 50.4 21.3 9.7 6.7 19.1 9.0 11.8 20.7 27.0 10.1 13.1 16.3 23.8 14.4 10.6 20.1 35.4 31.0 6.7 16.0 10.4 15.2 7.7 17.7 6.1 12.1 9.1 17.5 11.8 8.9 10.2 10.5 8.7 5.8 16.1 4.6 9.9 10.0 5.3 4.6 4.5 6.3 3.2 7.9 8.5 9.8 4.1 5.2 3.2 3.7 2.5 5.9 5.4 4.3 4.4 9.7 6.8 9.4 5.2 4.6 41.8 8.0 3.7 4.9 15.0 6.0 5.3 3.9 7.0 6.6 2.6 9.0 7.6 3.9 5.6 5.1 8.2 3.8 4.4 7.3 12.0 7.9 11.3 6.5 4.3 5.1 9.3 14.1 2.5 6.5 4.7 6.2 14.9 7.8 15.1 2.7 3.5 4.0 3.2 4.1 4.7 4.0 9.4 7.9 1.8 5.1 4.3 2.2 15.2 4.6 16.1 6.9 3.2 7.9 7.8 7.6 10.0 4.2 8.7 9.6 8.8 7.1 9.9 2.1 5.8 9.3 5.3 14.3 20.1 22.5 20.7 15.4 19.7 19.1 9.0 16.3 12.1 0.0 7.7 5.2 22.9 4.6 17.8 32.7 28.1 13.4 4.5 26.2 23.6 37.5 162.5 21.0 2.6 11.2 33.1 23.3 14.0 23.8 11.3 45.7 1.1 16.0 11.6 12.7 22.0 11.1 9.4 1.0 13.3 7.6 11.8 44.1 16.4 8.5 13.9 23.7 10.6 92.2 32.2 12.9 7.5 9.4 11.7 3.6 30.4 13.1 23.0 22.0 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 32.3;testis: 41.1" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 70.0;Extravillous trophoblasts: 59.5;granulocytes: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved Nucleoplasm,Centrosome,Cytosol Yes Yes "Nucleoplasm, Centrosome, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 3.7 2.3 1.5 12.7 1.3 8.3 3.0 1.3 1.8 1.4 6.7 1.3 0.8 7.3 1.8 1.2 7.7 1.1 3.7 4.1 1.1 1.1 2.4 5.1 2.9 12.3 1.6 0.9 8.3 1.4 0.3 0.7 6.1 1.5 1.0 8.3 1.5 2.7 0.5 6.9 2.1 7.2 2.7 1.3 7.4 4.3 41.1 1.1 32.3 1.2 5.9 13.3 2.4 2.4 3.9 5.2 6.0 8.7 2.0 6.6 2.6 33.0 24.4 16.3 11.5 0.9 2.1 20.7 27.1 12.7 65.7 27.7 68.2 23.2 10.8 18.7 11.1 34.1 26.7 29.0 18.2 70.0 9.8 11.1 19.3 25.0 42.5 0.5 25.8 27.2 1.0 1.9 22.7 20.4 5.2 15.3 17.7 21.9 8.6 27.9 33.7 15.4 20.0 14.9 27.1 25.1 11.7 31.5 12.0 10.5 8.7 14.1 7.6 37.9 43.6 18.2 15.6 25.8 16.1 8.8 28.6 28.3 15.8 38.2 12.1 14.0 18.8 15.4 15.0 23.6 0.2 5.3 6.0 1.9 8.7 2.9 3.9 3.3 1.9 5.2 1.4 1.5 1.5 3.7 2.0 4.8 1.2 6.6 2.6 1.5 1.3 1.3 1.8 1.1 1.1 1.6 0.9 1.5 1.1 0.0 3.2 4.5 1.1 1.0 1.0 3.4 2.5 1.4 2.3 3.5 2.0 9.8 1.7 3.9 16.9 1.6 5.3 70.0 4.2 59.5 3.8 0.7 55.2 2.4 14.8 1.6 5.8 3.1 2.4 9.5 1.4 5.5 0.0 18.0 5.7 3.5 3.6 3.5 0.4 1.9 2.5 6.5 2.1 16.2 31.6 1.0 6.9 4.9 9.8 1.4 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;lymphoid tissue: 59.9" "Group enriched" "Detected in many" 6 "Erythroid cells: 46.7;Extravillous trophoblasts: 76.2;Hofbauer cells: 23.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.9" "Lineage enriched" "Detected in many" 5 "T-cells: 10.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.2 1.3 0.4 22.1 0.6 19.7 2.0 0.6 0.6 2.6 5.8 0.5 0.9 5.9 0.9 1.3 17.1 0.3 2.2 1.0 0.4 0.2 1.4 1.8 2.4 17.8 0.4 0.4 0.8 0.6 0.0 0.4 3.8 0.8 0.9 5.5 0.7 2.7 0.4 2.1 5.0 8.1 1.3 0.7 11.2 4.2 1.2 0.4 59.9 0.5 8.0 19.1 2.1 5.0 2.3 0.8 1.2 0.6 0.5 10.9 1.4 41.6 28.6 42.7 20.5 0.9 1.4 16.4 20.0 10.8 41.5 38.3 37.0 12.6 41.6 10.4 7.9 17.3 30.7 30.9 13.7 34.3 18.2 50.8 24.8 16.4 31.2 0.1 13.0 24.4 0.7 0.6 24.3 15.2 4.1 19.0 27.4 15.4 16.1 18.1 19.8 47.5 18.6 26.5 13.7 12.7 32.2 39.3 17.2 9.0 8.2 9.3 13.2 17.8 8.0 13.6 13.3 14.0 8.8 7.4 16.6 17.1 14.9 52.0 11.8 7.8 31.3 8.0 19.9 33.6 0.0 0.6 0.9 0.6 0.4 0.2 1.6 1.9 3.1 0.8 2.3 0.2 1.0 1.2 0.5 0.3 0.2 10.9 1.4 0.4 0.6 0.6 0.6 0.4 0.2 0.4 0.4 0.8 0.4 0.0 0.3 2.2 0.3 3.9 0.0 1.1 0.0 0.0 3.4 0.0 0.0 5.1 0.0 0.2 0.0 0.0 1.4 46.7 0.0 76.2 4.7 0.4 4.6 0.6 23.9 0.0 0.0 4.9 6.3 0.0 0.6 4.4 1.7 0.0 4.2 0.0 0.2 2.9 0.0 0.0 0.0 0.0 0.3 0.7 2.0 2.0 7.6 2.5 6.3 1.4 AURKC "ARK3, AurC, STK13" ENSG00000105146 "Aurora kinase C" Q9UQB9 19 57230802-57235548 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 72.0" "Group enriched" "Detected in many" 4 "Early spermatids: 101.7;Spermatocytes: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "NTERA-2: 30.0" "Low region specificity" "Detected in all" HPA034859 Uncertain NA NA "HPA034859: AB_10670298" "unprognostic (7.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.45e-2)" "unprognostic (8.07e-3)" "unprognostic (3.29e-1)" "unprognostic (5.99e-2)" "unprognostic (1.11e-2)" "unprognostic (7.02e-2)" "unprognostic (1.13e-1)" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-5)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.55e-1)" "unprognostic (6.46e-4)" 0.6 0.5 0.9 0.9 1.2 0.7 1.5 0.7 2.0 0.4 0.6 0.6 0.2 0.0 0.8 1.3 0.5 0.6 2.6 0.9 0.9 1.1 0.8 1.8 1.3 2.2 1.2 0.2 0.4 0.5 0.1 1.3 1.2 1.7 0.5 0.8 1.1 0.5 0.9 2.3 0.6 0.4 1.1 2.1 3.4 0.4 72.0 0.6 0.7 0.8 1.0 1.3 0.5 0.4 2.1 1.0 1.7 1.0 1.0 0.6 0.2 0.2 0.1 0.7 0.3 0.2 0.7 0.3 1.3 0.6 0.9 3.5 0.9 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.7 0.6 0.0 3.8 0.1 0.3 0.0 1.1 0.0 0.2 0.9 0.7 0.7 0.5 1.1 0.6 0.4 0.1 0.0 1.2 0.0 1.1 0.6 30.0 0.1 0.8 0.1 0.2 0.6 0.7 1.2 1.4 0.4 0.0 0.2 0.1 0.1 0.1 1.3 0.3 0.2 4.2 0.3 0.7 1.4 1.9 0.6 0.8 0.0 0.0 0.0 0.1 1.7 0.6 1.0 0.0 1.9 0.0 0.0 0.9 2.1 0.0 0.0 0.1 1.0 0.3 1.0 0.0 0.2 0.9 1.2 0.7 1.6 0.9 1.1 1.2 0.2 1.7 0.6 0.0 0.3 0.0 0.6 1.0 2.5 1.2 0.0 1.4 3.4 1.8 0.0 0.4 1.7 1.5 101.7 0.6 0.0 0.0 0.9 0.7 0.4 1.1 0.0 0.0 3.2 0.0 1.7 1.8 1.3 11.5 1.4 1.0 5.0 1.8 0.0 1.7 0.9 0.3 0.4 0.3 0.8 6.5 0.5 69.6 19.2 1.0 0.2 0.0 0.4 1.4 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Basal glandular cells: 54.9;Basal keratinocytes: 60.9;Spermatogonia: 54.9;Suprabasal keratinocytes: 65.1;Urothelial cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" No No "Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 4.4 1.9 3.2 11.8 4.8 16.1 4.9 1.2 5.8 7.3 5.4 5.4 3.6 3.7 6.8 5.0 10.0 4.1 3.9 3.6 3.4 2.8 2.2 2.1 5.3 8.2 5.1 1.9 5.8 3.7 3.6 6.3 3.8 4.5 5.7 6.1 1.9 4.7 6.5 12.4 16.3 4.5 7.5 5.3 4.7 3.8 9.5 3.9 25.8 4.0 8.0 9.9 8.3 7.8 9.7 6.6 6.0 3.4 6.1 16.0 2.0 7.8 4.3 11.9 6.1 1.6 2.0 8.2 9.6 5.6 9.4 10.9 5.5 7.8 8.5 4.6 3.9 5.8 8.6 8.5 5.6 13.5 6.7 4.4 8.4 8.0 5.8 0.6 9.4 8.5 2.7 0.8 8.3 4.6 3.2 3.2 9.4 4.7 23.9 9.1 6.5 16.8 9.8 9.4 4.9 2.2 14.5 12.0 7.7 2.8 6.6 3.7 6.0 8.8 10.1 3.5 7.1 10.3 9.4 2.7 12.2 8.6 7.1 8.6 7.2 8.0 17.2 4.9 7.2 8.1 2.9 1.7 6.0 4.8 3.4 3.1 8.9 5.3 5.2 3.0 9.7 2.5 3.6 0.5 6.1 2.9 6.6 16.0 2.0 3.2 4.8 1.2 5.8 3.4 2.8 5.1 1.9 4.5 3.9 6.0 2.1 9.5 54.9 60.9 3.3 12.5 15.3 12.0 9.1 8.7 0.0 9.4 3.3 6.8 8.1 7.5 3.4 23.3 6.0 13.6 7.7 21.0 15.0 3.6 10.6 1.6 1.2 12.3 8.8 3.6 5.8 8.8 3.3 17.2 11.3 3.3 5.6 5.8 9.6 0.6 6.8 19.4 15.5 19.7 54.9 65.1 4.2 8.6 11.0 57.3 BCKDK ENSG00000103507 "Branched chain ketoacid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 26.8;granulocytes: 26.6;monocytes: 33.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 15.4 29.7 11.9 13.1 15.0 9.4 18.3 18.8 21.3 11.7 14.1 9.6 19.9 11.2 14.8 14.9 14.9 13.8 15.1 39.2 14.2 10.3 21.3 46.5 18.2 32.5 10.7 17.3 15.1 52.4 17.4 8.9 11.4 13.2 14.9 9.9 10.4 33.9 25.7 67.7 21.5 12.2 19.9 15.6 16.0 19.9 11.2 9.3 8.0 11.7 25.9 10.6 15.3 12.0 6.9 26.8 26.6 33.0 6.3 6.8 13.6 18.2 20.5 11.6 17.4 14.3 14.4 12.6 15.9 19.6 24.8 24.3 13.4 12.2 17.1 23.1 19.8 12.1 12.7 8.2 27.7 16.0 13.8 25.4 18.5 13.9 24.3 25.2 9.6 17.0 21.1 11.2 21.2 17.7 22.8 26.4 13.1 9.3 16.2 37.1 31.1 8.8 12.7 9.8 8.5 16.6 17.9 16.9 31.5 18.9 12.6 17.9 16.4 12.3 30.5 9.9 10.4 18.4 9.2 16.9 18.9 10.9 19.4 13.2 16.9 6.0 6.1 21.5 13.9 17.7 12.2 33.0 23.1 5.7 27.4 5.6 6.9 5.2 4.2 26.8 5.4 4.4 5.0 26.6 6.3 19.3 5.8 6.8 13.6 11.9 15.0 18.8 21.3 14.2 10.3 10.7 17.3 13.2 9.3 17.9 17.8 27.4 21.2 16.5 11.0 32.1 25.5 13.4 9.1 19.2 0.0 47.3 68.0 57.7 2.2 20.9 39.3 0.0 68.3 54.7 20.7 26.1 33.4 34.7 83.9 11.1 19.1 27.0 41.9 3.6 19.2 56.7 11.8 95.6 20.5 22.1 49.3 40.3 24.1 65.3 7.2 45.3 28.9 16.7 15.2 24.0 58.0 14.4 26.7 19.3 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR, RhoGEF and GTPase activating protein" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Ito cells: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "K-562: 44.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 14.5 8.4 24.0 9.1 41.2 26.7 10.5 14.2 26.5 13.6 9.7 10.3 10.6 8.7 9.2 13.9 19.3 10.8 8.3 7.8 20.9 13.0 16.3 8.3 11.3 10.9 16.0 15.6 8.8 12.9 14.5 14.9 15.7 14.2 7.0 6.8 8.3 15.5 9.7 3.4 12.8 8.7 9.0 9.5 9.1 14.0 9.6 15.4 11.8 16.6 5.5 9.2 9.2 8.8 1.5 0.8 1.2 1.0 2.8 6.6 2.5 19.0 8.2 12.7 13.0 7.6 5.2 19.2 6.9 6.5 6.4 5.2 14.4 7.7 13.3 12.9 5.9 6.2 19.6 1.3 19.2 1.8 25.4 13.2 11.6 11.3 11.4 9.9 10.7 6.1 4.4 13.0 9.5 8.4 11.4 22.3 9.6 44.4 6.3 2.9 12.5 10.0 8.4 10.7 15.1 8.1 13.2 5.1 8.7 9.9 12.1 11.7 11.1 12.6 10.9 5.2 8.5 6.9 8.8 25.1 3.8 0.4 6.2 5.7 1.4 5.8 4.7 9.9 8.1 5.9 0.0 1.0 0.0 6.6 0.4 2.3 1.4 3.3 3.3 0.8 1.5 2.6 3.6 1.2 2.8 1.0 0.8 1.6 2.5 24.0 41.2 14.2 24.9 20.9 13.0 16.0 15.6 14.2 15.4 8.9 11.5 3.0 9.5 13.7 24.0 7.3 20.4 2.7 19.4 17.4 21.6 10.5 8.3 12.4 3.9 22.4 11.1 0.0 14.1 5.9 7.3 10.2 10.4 18.4 6.0 22.3 19.1 62.0 10.8 7.7 8.1 5.4 5.0 6.4 12.0 13.4 21.8 5.8 5.3 14.3 8.0 0.0 8.6 1.6 6.8 13.8 9.0 9.2 11.2 11.5 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 180.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 15.0 16.7 10.3 20.7 14.4 18.4 16.1 21.9 13.7 16.2 13.0 15.3 15.6 8.7 17.2 13.9 13.2 13.1 11.7 11.4 9.8 7.3 14.1 14.8 12.5 16.1 13.9 11.8 23.6 24.8 32.5 17.4 14.1 14.8 11.3 13.6 11.5 14.7 17.1 20.9 14.9 16.0 12.5 13.3 16.1 13.9 13.0 14.4 23.1 21.5 9.2 17.2 16.2 12.0 3.8 2.8 10.6 2.4 2.3 3.4 0.7 15.3 12.8 11.9 5.1 9.4 13.4 7.2 6.8 9.6 8.4 8.0 8.8 3.6 16.4 5.4 12.7 9.6 7.1 16.7 10.1 10.4 13.2 7.6 22.3 8.1 7.3 5.2 20.6 7.9 8.9 4.9 13.1 11.7 6.8 12.4 3.7 18.1 7.1 7.7 5.9 10.3 4.8 8.0 5.8 7.6 10.5 19.3 5.6 6.1 15.8 8.9 13.6 13.4 7.0 6.2 9.5 4.6 7.4 19.4 8.8 9.9 5.9 10.4 9.5 13.3 22.0 6.4 10.2 5.7 10.6 1.6 0.9 2.7 1.2 3.4 1.7 2.1 2.3 1.3 3.8 2.3 2.6 2.7 2.3 2.4 2.8 1.6 0.7 10.3 14.4 21.9 13.7 9.8 7.3 13.9 11.8 14.8 14.4 29.8 26.2 37.9 25.6 40.9 59.4 42.2 30.6 10.7 35.2 34.9 180.6 28.6 1.7 22.3 35.8 45.7 44.5 0.0 26.8 18.3 30.5 38.3 29.9 44.3 26.3 65.2 31.2 46.1 58.6 13.7 42.0 32.8 21.9 31.5 36.3 39.9 28.2 25.9 55.5 19.2 89.9 38.8 42.4 52.0 44.5 47.9 31.8 56.8 37.0 38.9 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916372 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "granulocytes: 124.9;Hofbauer cells: 112.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 38.8;HMC-1: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favorable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 11.4 11.1 15.6 18.6 15.0 15.3 12.0 8.2 12.7 11.1 13.9 20.3 2.1 8.0 11.3 9.6 15.7 10.0 12.3 17.0 18.0 9.5 8.3 10.2 14.1 22.9 20.9 12.0 6.5 6.4 7.7 7.8 14.4 14.5 8.4 18.9 11.4 10.2 6.0 7.5 14.5 15.9 10.4 28.3 19.2 7.4 19.6 16.5 19.9 12.5 5.9 24.4 9.7 12.8 2.7 1.7 3.8 2.6 0.4 0.4 0.5 5.5 2.0 3.0 4.0 6.0 5.8 2.4 5.4 8.3 6.0 7.9 3.8 2.9 6.7 2.7 25.8 5.2 1.3 3.6 4.3 11.0 1.9 1.3 38.8 2.4 1.7 6.7 8.1 42.0 8.4 5.6 9.4 8.7 3.2 8.1 4.9 10.4 19.5 7.1 1.2 4.8 3.4 1.4 3.7 1.4 7.0 5.5 1.6 7.3 3.0 4.8 2.6 7.8 4.0 4.7 3.8 1.4 4.2 7.9 5.9 2.3 9.8 5.7 3.6 1.4 2.6 5.2 10.2 4.1 0.4 2.2 1.2 0.1 0.9 0.1 2.7 0.1 0.0 1.7 2.7 0.4 0.2 3.8 0.4 2.6 1.3 0.0 0.5 15.6 15.0 8.2 12.7 18.0 9.5 20.9 12.0 14.5 16.5 26.8 18.1 10.4 3.8 22.1 9.6 5.7 2.5 6.7 6.8 7.0 3.9 4.0 0.0 7.0 11.1 12.4 19.7 46.7 7.6 11.6 12.4 6.3 124.9 16.3 112.6 9.5 6.4 30.7 61.7 7.6 7.5 31.6 27.0 22.6 41.6 46.4 10.6 48.2 6.3 18.1 8.4 6.5 7.4 24.1 9.6 27.5 2.9 3.9 21.8 2.3 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932838 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 8.9 7.0 9.4 7.9 12.4 0.9 10.7 14.1 9.2 19.4 20.6 10.9 7.7 6.2 16.3 12.3 8.4 10.9 10.8 11.0 7.7 6.1 8.2 4.6 7.4 2.9 7.3 7.6 16.1 10.6 10.0 14.0 7.4 8.5 12.8 9.3 10.9 12.6 14.2 8.4 11.3 9.8 16.5 12.2 3.4 12.1 7.8 9.2 0.3 19.4 7.8 5.7 16.0 11.4 1.8 1.1 3.6 0.8 0.9 1.4 0.3 7.3 3.7 14.3 12.1 7.5 4.8 2.5 7.4 7.7 4.3 5.1 6.2 6.4 2.2 3.4 9.4 3.1 7.8 6.3 8.0 6.4 2.4 3.6 2.8 3.5 10.3 4.0 3.8 19.7 4.2 3.4 5.8 4.3 6.4 0.0 4.1 4.4 1.5 5.0 3.1 2.6 3.1 7.7 2.6 1.7 0.0 5.6 0.0 8.9 6.9 1.4 4.6 8.2 4.2 4.9 18.2 7.1 1.9 3.7 3.1 5.0 6.4 6.8 0.4 6.8 2.8 2.7 2.6 2.5 2.0 0.8 0.6 1.4 0.5 0.9 1.8 1.4 1.2 0.3 1.5 1.0 1.1 3.6 0.9 0.6 1.1 0.7 0.3 9.4 12.4 14.1 9.2 7.7 6.1 7.3 7.6 8.5 9.2 32.8 24.8 0.0 6.7 10.8 6.0 19.0 10.2 13.4 9.1 10.4 19.6 10.0 1.7 9.8 0.6 2.1 9.0 0.0 8.1 0.7 13.3 12.9 15.0 7.2 2.7 11.1 17.3 8.0 4.0 1.7 31.1 3.5 8.5 1.0 13.6 12.9 7.7 3.5 29.4 4.7 19.0 6.5 14.1 2.3 3.6 8.5 4.2 0.0 10.0 4.2 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757968-95158448 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 28.0;ductus deferens: 25.1;prostate: 25.3;seminal vesicle: 32.0" "Group enriched" "Detected in many" 5 "Ciliated cells: 14.7;Club cells: 22.7;Collecting duct cells: 57.6;Glandular cells: 28.8;Intestinal endocrine cells: 17.6;Melanocytes: 27.0;Muller glia cells: 44.8" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 18.7;MCF7: 9.4;SH-SY5Y: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 1.1 5.6 12.7 0.8 15.0 0.7 1.7 11.6 12.7 28.0 1.2 5.5 25.1 0.7 5.3 3.2 1.1 14.3 3.4 1.3 13.4 5.9 9.3 1.4 2.4 0.5 5.4 8.6 7.6 1.7 0.6 2.4 1.2 12.1 25.3 0.8 0.7 1.4 32.0 3.3 1.4 0.6 1.2 7.5 1.4 2.8 4.3 11.2 10.8 0.8 0.1 0.6 0.7 0.7 0.4 0.5 1.9 0.9 0.8 1.6 0.3 0.0 18.7 5.0 0.0 2.0 4.6 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.8 0.0 1.0 2.9 6.9 0.0 0.0 4.6 0.0 1.1 0.0 0.5 0.4 0.0 2.8 7.6 2.8 5.7 0.3 0.0 0.0 0.0 0.0 7.2 9.4 0.6 0.1 1.8 0.1 3.2 0.1 2.8 0.1 3.6 0.1 0.2 15.6 0.2 2.5 2.5 0.7 1.9 0.0 0.0 4.0 3.2 0.1 3.4 0.0 0.0 0.0 1.5 0.0 0.4 1.9 0.3 0.5 0.4 0.5 0.7 0.4 0.6 0.3 0.3 0.3 0.5 0.5 0.8 0.8 0.9 0.5 1.6 0.3 12.7 15.0 11.6 11.8 13.4 5.9 5.4 8.6 12.1 11.2 6.0 0.0 0.0 1.3 2.4 0.2 3.6 5.1 14.7 22.7 57.6 0.0 0.0 1.7 2.9 1.1 0.3 0.0 0.0 0.3 0.2 1.4 28.8 0.0 0.0 0.1 0.0 17.6 4.9 0.0 1.6 2.8 0.3 27.0 0.0 0.0 44.8 0.7 0.0 3.5 0.0 1.2 0.0 1.4 1.6 1.3 1.9 0.0 0.0 0.0 1.0 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376936-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.1 15.0 12.1 9.8 14.2 1.1 10.2 9.5 17.1 15.7 11.7 8.2 6.5 5.5 12.9 10.2 10.6 10.3 13.2 14.6 10.8 13.5 10.7 11.5 24.9 4.4 10.4 14.5 12.0 7.0 15.5 6.1 21.7 10.8 11.0 7.7 11.4 7.1 9.1 10.6 7.2 8.1 15.3 7.5 8.9 7.2 12.9 3.8 3.9 11.6 5.2 5.4 11.1 8.9 1.6 2.6 0.9 2.7 1.1 3.6 0.9 5.7 5.4 5.6 8.8 14.0 13.6 10.8 12.0 12.1 10.5 10.5 4.7 8.7 2.0 14.0 24.2 9.0 10.9 7.3 9.3 16.5 6.0 5.0 6.1 5.8 7.3 9.7 1.7 4.8 9.9 8.8 7.7 10.3 16.2 30.2 2.5 3.9 10.0 12.9 10.8 1.4 1.6 3.1 2.8 5.0 3.9 11.0 3.0 8.9 12.3 5.7 5.7 12.8 7.6 14.1 14.3 5.9 4.0 33.3 21.4 11.4 7.3 7.2 1.4 1.7 0.6 5.1 3.9 6.2 0.5 2.0 0.9 3.4 1.8 2.5 1.5 1.3 2.2 2.3 1.6 2.7 1.4 0.6 1.1 2.7 2.6 3.6 0.9 12.1 14.2 9.5 17.1 10.8 13.5 10.4 14.5 10.8 3.8 98.3 38.9 17.1 16.1 29.8 51.7 46.4 12.7 21.4 39.8 19.2 76.6 14.0 1.7 27.3 2.4 119.4 12.7 0.0 24.7 19.4 40.9 19.9 23.1 15.5 16.2 33.4 24.1 109.2 20.0 2.3 31.4 17.4 40.5 15.4 16.3 38.7 36.3 20.9 40.3 10.7 29.9 64.7 45.7 17.7 11.1 31.5 16.7 13.8 13.4 22.7 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924928 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol No No Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 13.1 12.1 20.1 16.5 20.4 27.8 14.2 29.9 21.5 12.4 12.3 9.5 12.5 9.3 15.3 17.0 11.8 11.5 12.0 13.6 13.2 12.2 13.7 12.8 15.9 13.3 9.9 17.8 16.8 13.2 28.9 24.8 13.7 15.3 14.5 11.0 10.7 11.6 16.6 12.9 15.6 10.5 13.0 10.9 12.3 12.0 24.9 12.2 13.5 16.6 7.5 12.1 18.6 18.1 2.6 1.9 7.5 2.4 7.0 5.6 1.1 5.5 4.7 6.9 8.3 8.4 11.0 11.1 6.2 6.6 5.0 7.2 5.1 6.0 9.5 4.8 6.4 8.0 3.1 6.1 4.9 9.3 8.8 5.0 6.2 4.6 4.7 7.2 10.0 6.2 7.3 5.6 5.3 11.1 7.4 5.8 7.1 9.7 17.1 8.8 2.9 13.3 10.5 6.4 5.4 3.0 8.7 5.9 7.7 4.9 10.7 8.1 6.8 7.2 4.4 6.5 7.1 4.1 6.8 8.6 5.5 4.2 11.7 5.0 19.8 11.2 15.2 8.9 10.1 5.9 3.3 2.0 7.5 3.1 1.7 2.1 2.6 3.0 2.4 1.6 2.6 5.6 2.8 4.1 7.0 2.4 1.9 2.7 1.1 20.1 20.4 29.9 21.5 13.2 12.2 9.9 17.8 15.3 12.2 20.8 34.2 19.5 20.3 19.2 29.1 12.7 5.1 24.1 25.0 24.4 33.4 12.4 6.6 10.9 55.6 17.1 7.5 0.0 8.6 10.3 13.1 23.9 24.3 8.7 7.9 23.8 18.4 8.6 14.8 30.8 15.3 17.2 15.1 10.0 8.1 11.8 12.5 6.6 9.6 9.6 32.5 6.5 17.3 33.7 23.0 21.0 63.2 17.5 8.1 23.8 BRAP "BRAP2, IMP, RNF52" ENSG00000089234 "BRCA1 associated protein" Q7Z569 12 111642146-111685986 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.9" "Group enriched" "Detected in many" 5 "Early spermatids: 224.1;Late spermatids: 273.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040357, HPA058820" Approved Supported "Nuclear membrane,Cytosol" NA NA Cytosol "Nuclear membrane" "HPA040357: AB_10967924, HPA058820: AB_2683827" "unprognostic (7.02e-2)" "unprognostic (2.37e-3)" "unprognostic (5.33e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.65e-6)" "unprognostic (2.14e-1)" "unprognostic (9.24e-3)" "unprognostic (2.80e-1)" "unprognostic (1.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (3.66e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-2)" "unprognostic (8.08e-2)" 9.8 9.9 9.8 7.2 11.6 26.5 9.6 10.0 12.8 8.3 9.3 10.0 8.0 8.6 10.1 7.0 9.4 8.4 7.3 8.8 8.6 8.7 8.4 9.3 7.9 9.7 9.2 8.5 9.7 7.8 9.4 10.4 9.8 12.0 8.3 9.0 6.7 8.9 9.7 19.1 12.7 9.3 9.1 11.1 9.6 7.9 55.9 10.1 12.4 9.5 5.6 10.4 10.2 11.8 12.7 11.7 25.7 13.5 16.6 18.5 11.6 9.9 14.6 12.0 13.7 12.8 10.8 20.0 13.9 11.7 16.2 12.5 19.6 6.9 19.1 8.4 13.1 9.2 12.2 16.7 11.4 17.4 12.2 10.8 23.6 9.1 13.1 16.2 20.7 16.0 12.2 16.2 14.0 22.8 14.0 14.0 13.3 24.5 6.3 13.3 12.5 17.2 20.0 16.1 10.5 15.4 16.0 13.0 17.0 10.7 20.9 14.9 11.0 16.3 13.9 13.6 14.4 15.3 13.2 12.9 10.4 9.7 9.4 9.8 16.1 20.3 21.1 9.9 11.5 11.4 16.1 13.0 24.0 14.7 13.5 14.3 12.7 15.4 14.7 11.7 12.5 14.6 14.8 25.7 16.6 10.6 8.4 18.5 11.6 9.8 11.6 10.0 12.8 8.6 8.7 9.2 8.5 12.0 10.1 20.8 9.1 7.5 8.2 10.0 8.1 10.6 17.8 13.4 10.3 10.4 27.5 11.4 5.0 11.0 224.1 9.3 12.8 0.0 6.6 12.6 8.5 9.9 8.1 7.9 9.3 3.2 9.2 8.6 6.4 273.6 12.4 11.3 3.3 20.8 10.6 7.8 11.8 10.5 12.7 11.9 11.5 6.5 10.7 49.2 33.7 11.0 18.8 10.1 9.3 11.2 BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748018 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" 10.5 7.7 6.2 10.4 8.1 29.2 10.7 16.5 13.1 10.7 9.5 10.4 5.0 6.8 14.4 8.9 10.7 12.9 10.7 7.0 5.4 4.2 8.2 5.3 10.7 12.3 8.3 7.0 12.5 9.2 11.3 9.5 9.9 7.5 9.0 6.3 9.6 12.1 8.5 11.1 14.2 10.5 8.3 5.1 12.2 9.2 23.7 11.4 24.3 12.0 7.8 11.4 11.5 9.4 1.2 3.5 2.3 1.8 9.3 4.2 1.3 5.4 8.5 8.4 4.1 5.3 4.5 43.2 6.7 4.5 7.9 5.9 7.5 4.6 9.4 3.1 6.7 7.8 4.6 8.5 6.8 5.7 9.9 9.1 12.1 16.9 5.0 6.2 17.1 11.3 5.7 5.7 11.7 7.0 4.4 6.1 9.8 12.8 9.5 4.9 13.1 10.7 14.1 10.7 4.0 8.0 14.4 5.9 6.5 4.2 8.6 5.0 7.8 7.3 5.2 6.2 5.5 5.3 16.7 7.7 9.4 8.0 8.0 12.4 7.7 8.6 17.4 7.3 14.1 8.0 2.2 1.8 2.3 2.7 1.6 4.2 1.1 2.1 2.5 1.5 1.2 2.5 2.9 1.3 9.3 1.5 3.5 1.3 1.3 6.2 8.1 16.5 13.1 5.4 4.2 8.3 7.0 7.5 11.4 14.9 10.6 4.5 4.7 12.6 4.4 3.5 0.0 4.0 7.9 7.0 5.9 3.6 0.0 3.6 1.6 7.5 4.4 0.0 4.7 4.6 4.1 4.4 8.1 2.4 5.5 7.9 9.8 8.6 4.8 0.4 6.1 5.2 1.7 1.0 5.0 4.5 4.3 2.9 5.6 1.8 3.8 6.5 4.7 15.8 11.7 16.2 3.1 7.5 5.8 5.5 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312533 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.0" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 30.8;Enterocytes: 12.3;Horizontal cells: 36.5" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 26.2;SH-SY5Y: 23.6;WM-115: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.4 9.8 28.6 3.2 23.6 1.0 1.6 26.7 65.0 1.8 2.2 7.9 0.1 3.3 5.4 3.7 3.0 2.3 3.9 6.5 33.4 20.0 1.4 0.8 1.7 2.4 20.4 14.8 2.4 2.6 12.4 11.0 1.5 13.3 3.8 1.9 2.8 2.5 4.6 1.0 1.1 2.6 4.9 9.2 1.5 1.9 4.4 7.2 0.0 3.0 0.0 1.6 3.2 0.7 0.0 0.3 0.0 0.9 0.1 0.8 0.2 0.3 1.3 15.5 8.2 0.0 0.6 0.1 2.4 3.4 3.3 4.9 5.9 2.7 3.1 1.7 2.8 3.1 0.1 3.2 0.1 3.1 14.6 12.8 2.0 1.6 0.6 3.3 0.6 6.0 2.2 0.3 3.4 0.0 12.9 0.1 8.2 2.8 19.1 3.0 0.8 3.7 0.7 11.2 0.3 1.0 8.5 3.9 0.5 0.2 0.0 26.2 23.6 0.0 0.4 5.7 4.6 1.3 1.7 0.0 6.4 6.8 3.5 4.6 15.8 11.6 7.1 6.5 1.4 21.4 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 28.6 23.6 26.7 40.2 33.4 20.0 20.4 14.8 13.3 7.2 0.0 2.2 0.0 1.0 0.1 30.8 0.8 0.0 0.0 1.2 1.8 2.0 0.0 0.0 0.3 0.8 0.3 12.3 0.0 0.0 0.0 0.5 0.8 0.0 0.0 1.4 36.5 3.4 0.0 7.8 0.0 0.6 0.4 0.0 0.0 1.0 3.2 0.2 0.0 4.6 0.8 10.2 0.0 1.0 3.9 6.5 0.0 0.0 0.8 1.2 0.1 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Group enriched" "Detected in some" 6 "Bipolar cells: 79.7;Cone photoreceptor cells: 33.4;Horizontal cells: 65.2;Muller glia cells: 24.5;Rod photoreceptor cells: 27.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 9.1;AN3-CA: 9.9;CACO-2: 7.9;HAP1: 7.4;NTERA-2: 15.3;SCLC-21H: 35.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 4.0 9.1 9.9 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.9 0.5 0.0 1.4 0.1 0.1 0.0 7.4 0.0 0.6 0.9 3.9 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.2 0.0 0.3 0.1 0.0 0.1 0.9 0.0 0.0 15.3 2.7 1.2 0.0 0.0 0.0 0.1 0.1 35.8 5.3 1.8 0.1 2.5 0.2 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 0.0 0.0 0.0 0.1 0.2 79.7 2.2 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.9 0.0 0.2 0.2 0.0 0.0 0.2 65.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 24.5 0.5 0.0 1.1 0.0 27.0 6.5 8.0 0.7 1.5 0.0 0.0 0.0 0.0 0.0 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637698-110678114 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 56.5;testis: 30.9" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 68.1" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 1.1 0.9 0.5 15.8 1.0 8.9 0.6 0.3 1.0 1.2 2.8 0.4 0.0 2.4 0.7 2.3 5.8 0.5 1.0 1.1 0.5 0.5 0.9 0.8 2.1 11.6 0.6 0.2 1.0 0.7 0.0 0.4 2.4 0.5 0.7 4.3 0.4 1.4 0.0 0.5 1.8 3.1 1.4 1.3 7.9 1.8 30.9 0.1 56.5 0.6 5.7 12.1 2.5 2.0 1.8 2.4 3.0 0.2 1.4 6.1 1.1 30.3 8.9 23.4 14.7 1.0 1.7 12.4 15.8 10.4 27.5 20.8 18.7 17.5 20.6 9.8 9.1 25.8 13.3 29.9 11.5 34.2 16.3 14.6 68.1 9.5 14.9 0.2 19.6 19.3 0.4 0.7 21.2 10.5 3.9 16.1 23.1 29.8 43.0 22.5 10.0 32.8 16.4 22.6 10.8 16.9 21.8 20.0 31.4 5.6 9.6 15.7 6.8 11.2 9.6 8.5 14.9 7.5 16.6 6.6 12.5 20.5 9.4 21.9 22.5 21.1 25.3 8.5 15.2 22.0 3.0 0.0 0.7 0.6 0.2 0.9 1.8 2.5 1.0 0.8 1.4 1.6 1.5 0.0 1.4 0.1 2.4 6.1 1.1 0.5 1.0 0.3 1.0 0.5 0.5 0.6 0.2 0.5 0.1 0.0 1.0 7.8 0.2 0.5 0.0 0.8 0.0 1.4 2.3 0.0 0.0 1.3 0.0 0.2 8.3 0.0 0.0 0.0 0.0 8.1 0.3 0.2 0.0 0.2 6.6 0.0 0.0 1.3 1.3 4.7 0.3 1.7 0.0 1.0 0.9 0.0 0.1 0.0 0.4 0.0 0.0 6.5 0.0 68.0 14.1 0.4 0.6 2.5 2.0 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Group enriched" "Detected in many" 7 "Spermatocytes: 66.9;Spermatogonia: 28.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA008419 Supported Cytosol Yes Yes Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.8 11.1 35.5 14.1 0.9 2.5 11.5 20.8 11.7 22.3 19.4 16.2 8.4 19.8 11.7 7.5 20.5 24.7 33.5 11.3 24.3 17.0 18.0 28.9 28.7 15.0 0.0 26.1 15.9 0.5 0.6 13.6 12.8 4.4 16.1 22.9 24.9 21.1 22.2 7.4 20.4 15.9 24.0 18.4 12.7 21.9 29.2 15.0 6.8 11.1 23.2 14.3 12.8 12.3 4.5 16.2 14.3 13.5 9.3 17.1 18.1 17.0 18.4 11.1 18.8 32.4 9.1 29.3 22.2 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 3.0 1.4 0.8 0.3 0.7 0.4 0.4 0.0 0.0 3.4 0.0 0.0 1.3 0.0 0.3 2.5 0.0 0.3 0.0 0.0 5.1 0.4 0.2 0.0 0.2 4.3 0.0 0.0 1.3 0.6 2.4 1.4 1.5 0.0 0.0 1.4 0.0 0.8 0.8 0.4 0.0 0.1 6.5 0.0 66.9 28.8 0.3 0.7 0.8 1.7 0.4 CALM1 "CALML2, CAMI, DD132, PHKD" ENSG00000198668 "Calmodulin 1" P0DP23 14 90396502-90408261 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 176.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB018558, HPA044999" Supported Approved Vesicles NA NA Vesicles "CAB018558: AB_2069454, HPA044999: AB_2679177" "unprognostic (5.35e-3)" "unprognostic (3.96e-1)" "unprognostic (4.99e-3)" "unprognostic (2.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.52e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" "prognostic favorable (5.62e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.49e-4)" "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.38e-5)" 47.5 28.1 141.5 26.9 148.2 57.2 21.5 149.6 176.0 27.4 55.9 49.4 20.7 53.9 20.3 41.7 58.8 48.6 29.5 52.3 139.8 86.1 61.5 39.0 38.7 27.8 85.2 100.1 20.9 22.6 41.4 27.6 38.6 106.1 33.7 60.5 22.2 33.2 43.5 100.2 19.3 50.6 42.6 71.1 29.3 35.6 22.3 49.8 12.6 22.7 18.8 37.8 32.7 21.8 45.7 42.8 90.3 53.7 88.8 118.3 109.4 26.9 37.6 44.9 17.2 50.5 44.5 38.4 49.8 42.7 38.5 41.8 40.0 47.9 29.2 26.0 58.7 18.1 45.2 28.1 69.2 64.2 56.8 18.0 30.9 32.4 36.6 27.7 46.8 24.9 27.9 34.6 37.7 13.4 25.6 86.8 20.3 14.2 40.1 52.7 91.7 15.4 45.8 26.1 74.4 52.6 30.9 40.1 19.7 31.8 83.3 94.1 39.5 43.5 76.2 27.8 38.9 50.4 16.4 53.8 32.5 20.8 34.0 41.4 22.4 50.6 32.1 51.4 39.4 45.1 90.3 31.8 71.0 96.0 37.9 118.3 45.7 102.5 101.0 42.8 35.7 74.8 88.1 47.0 88.8 53.7 40.5 105.6 109.4 141.5 148.2 149.6 176.0 139.8 86.1 85.2 100.1 106.1 49.8 360.3 314.0 329.2 485.1 503.7 1352.9 743.7 341.4 1962.0 494.8 378.6 115.8 358.0 389.6 484.7 100.9 794.0 1033.1 23.3 391.9 774.4 358.4 298.0 468.8 297.5 680.0 570.5 576.0 585.0 268.2 58.5 195.1 732.5 595.5 1203.7 393.5 1076.8 427.8 540.1 470.2 1073.9 291.0 310.4 582.3 94.1 162.2 507.4 959.8 581.7 530.3 385.0 CALM2 "CAMII, PHKD" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160082-47176601 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB007790, HPA044999" Approved NA Yes "CAB007790: AB_562257, HPA044999: AB_2679177" "prognostic unfavorable (5.05e-4)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.84e-4)" "unprognostic (9.21e-2)" "unprognostic (2.04e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (1.63e-2)" "unprognostic (4.67e-3)" "unprognostic (1.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-2)" "prognostic favorable (1.94e-5)" "unprognostic (1.24e-1)" 65.6 87.3 153.0 41.3 162.1 25.3 89.8 132.9 169.5 58.4 88.7 62.8 38.8 68.4 60.1 73.8 50.8 71.6 51.3 55.0 160.4 133.1 57.9 62.0 63.9 48.4 135.8 147.6 57.5 28.1 37.7 51.2 59.3 119.6 60.4 92.3 29.3 60.4 77.7 30.2 31.0 77.7 81.7 139.9 77.3 50.0 79.1 114.9 43.8 60.0 31.0 57.1 56.5 37.1 53.2 82.3 190.9 141.0 38.4 40.3 130.5 165.2 63.6 73.6 32.6 42.0 47.6 47.2 163.8 101.5 97.6 84.2 62.5 62.2 70.4 74.4 119.1 72.0 43.0 62.4 57.7 128.7 53.9 29.5 60.0 38.3 90.9 54.1 72.8 47.5 27.2 56.2 87.0 98.6 85.5 65.4 23.1 56.2 58.0 232.8 43.3 84.9 62.8 57.1 201.5 32.5 21.2 86.9 66.5 109.4 30.3 54.0 137.6 52.9 52.5 71.2 82.5 39.0 38.9 75.4 72.8 80.7 43.6 114.7 46.1 40.3 74.9 49.5 50.4 93.3 140.3 98.3 190.9 29.8 141.0 32.3 53.2 37.2 35.8 82.3 36.9 33.2 36.4 102.4 38.4 122.1 78.5 40.3 130.5 153.0 162.1 132.9 169.5 160.4 133.1 135.8 147.6 119.6 114.9 1289.3 525.2 388.5 961.5 1581.7 610.3 547.0 499.4 2395.7 1222.7 720.6 92.3 798.8 1953.0 1859.0 214.5 598.0 903.4 654.1 600.7 481.0 1210.0 791.7 634.5 511.4 1131.6 322.6 573.5 257.8 884.6 184.8 977.2 1240.6 1680.3 1146.1 906.5 1779.4 1759.7 1027.7 811.8 737.6 257.4 892.6 1822.0 1588.7 733.3 1453.8 213.5 621.1 614.7 973.8 CALM3 PHKD ENSG00000160014 "Calmodulin 3" P0DP25 19 46601074-46610793 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease mutation, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 181.1" "Cell type enhanced" "Detected in all" 9 "Early spermatids: 1472.6;Late spermatids: 2084.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044999 Approved NA NA "HPA044999: AB_2679177" "unprognostic (3.39e-1)" "unprognostic (1.30e-1)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" "unprognostic (9.81e-2)" "unprognostic (1.29e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.01e-3)" "unprognostic (5.28e-2)" "unprognostic (1.67e-1)" "unprognostic (5.34e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" "unprognostic (1.07e-1)" "prognostic favorable (9.10e-4)" "unprognostic (2.72e-1)" 23.0 29.0 113.3 27.0 142.8 30.5 15.6 76.6 181.1 27.4 31.6 21.5 8.2 37.4 24.5 18.8 22.5 25.9 25.2 47.5 120.2 75.6 23.4 25.3 19.3 29.7 70.1 110.8 37.4 19.3 16.5 16.0 24.5 90.5 25.6 30.0 17.8 12.4 31.6 52.7 15.3 41.7 31.3 34.7 18.5 22.8 44.7 20.5 27.1 22.3 8.6 30.6 28.5 17.4 13.0 17.4 82.2 34.2 18.8 35.3 26.8 52.7 62.2 73.3 25.8 38.8 52.0 15.8 54.0 49.6 53.3 71.3 52.5 51.2 45.1 22.7 86.6 37.7 37.2 72.8 47.0 68.0 54.9 47.1 61.8 30.4 60.0 21.0 49.0 84.7 50.8 16.0 41.3 33.2 41.1 66.0 52.4 45.5 67.8 50.5 36.1 47.3 109.8 34.3 82.8 24.5 83.4 39.0 17.1 50.5 66.5 37.2 39.6 44.0 29.6 17.2 76.0 34.3 53.1 47.2 28.9 50.3 22.1 42.1 42.6 34.3 36.7 29.4 39.9 37.9 28.5 30.2 46.3 13.0 34.2 11.7 13.0 18.7 17.4 17.4 11.5 21.7 14.0 82.2 18.8 33.2 10.4 35.3 26.8 113.3 142.8 76.6 181.1 120.2 75.6 70.1 110.8 90.5 20.5 38.7 58.6 96.7 64.3 50.8 127.6 153.9 81.5 71.0 31.8 66.3 11.8 167.0 220.5 222.6 1472.6 81.0 327.1 327.1 193.5 389.2 117.3 73.9 104.9 82.7 633.9 84.2 117.6 106.8 253.0 2084.0 99.0 107.0 87.7 757.4 160.9 101.7 206.9 178.9 115.2 292.8 57.1 90.5 138.2 657.1 168.6 57.6 154.6 174.0 160.4 94.5 CAMK1 CaMKI ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757342-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.5;blood: 59.4" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 76.7;Sertoli cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 59.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 59.4" "Cell line enriched" "Detected in many" 4 "HMC-1: 94.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 550000 Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 27.1 60.5 28.0 11.7 26.0 3.5 34.1 12.4 31.2 9.5 10.7 4.4 5.8 6.8 12.6 10.5 7.1 12.6 8.9 10.2 21.4 14.0 13.1 20.7 9.2 10.4 10.3 19.9 21.5 4.5 7.4 7.9 5.1 10.1 18.6 8.1 6.8 5.1 15.1 4.7 3.3 8.3 18.4 7.2 7.1 8.1 13.4 5.6 0.6 7.0 3.7 10.4 9.5 10.3 0.0 3.2 59.4 9.2 0.7 0.4 0.9 0.1 3.7 3.0 0.0 15.4 5.7 7.5 8.8 4.9 10.1 9.6 5.4 0.6 0.2 2.0 5.9 1.5 0.6 0.0 1.1 6.3 0.1 21.6 11.9 7.0 7.5 8.6 1.0 94.0 6.0 0.9 14.2 1.5 8.3 8.4 0.2 1.5 0.2 3.7 2.2 0.0 8.7 2.1 0.1 5.8 0.0 0.1 0.2 6.0 0.6 1.0 3.8 1.5 0.1 0.8 1.3 0.9 15.2 4.4 4.6 5.7 6.5 11.0 0.1 0.0 0.2 9.8 3.3 0.6 3.3 4.8 59.4 0.0 9.2 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.2 0.7 9.2 0.1 0.4 0.9 28.0 26.0 12.4 31.2 21.4 14.0 10.3 19.9 10.1 5.6 0.0 1.9 6.4 17.8 4.4 8.1 0.0 10.2 1.4 2.3 10.4 2.0 0.4 8.3 13.1 1.5 22.7 2.0 0.0 3.6 1.0 11.6 14.9 31.0 21.2 76.7 0.0 5.8 17.8 40.5 3.9 33.4 50.8 5.0 19.0 1.3 30.9 6.0 3.5 42.5 35.3 8.0 58.2 35.0 1.1 1.1 3.3 0.7 7.5 5.5 10.8 CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349482-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bipolar cells: 148.3;Cone photoreceptor cells: 369.1;Rod photoreceptor cells: 206.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 31.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 31.8" "Cell line enhanced" "Detected in many" "HDLM-2: 47.7;U-266/70: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favorable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" 5.1 5.3 20.9 10.5 22.1 6.6 4.0 23.4 33.5 8.3 11.5 4.6 10.0 3.8 3.3 3.3 8.7 4.3 6.8 13.8 18.6 7.2 2.2 11.5 7.6 9.3 5.8 17.8 2.6 17.0 1.3 2.5 3.2 5.0 4.9 12.9 11.9 4.5 15.4 1.7 18.5 5.5 5.6 4.9 10.5 3.4 6.2 6.8 20.8 13.6 2.9 12.5 8.1 7.0 7.1 4.2 31.8 3.7 1.4 2.3 1.3 0.1 2.6 3.0 0.2 1.8 0.6 0.2 0.4 0.9 0.6 0.9 3.6 2.0 1.4 0.3 0.2 1.5 1.4 3.6 0.5 0.5 47.7 1.8 5.7 8.5 0.2 0.5 0.1 5.2 0.1 2.3 1.2 0.1 6.4 0.3 3.1 0.1 0.2 0.7 3.0 11.1 2.3 2.0 0.0 1.2 8.5 1.6 2.6 0.1 2.8 4.6 2.1 5.7 2.1 0.0 0.4 1.5 1.4 0.1 2.5 3.7 7.9 1.7 22.0 6.9 4.8 3.7 3.7 0.0 8.3 2.2 31.8 1.8 3.1 1.9 5.6 1.6 2.3 4.2 7.1 1.9 1.3 13.9 1.4 3.7 1.4 0.5 1.3 20.9 22.1 23.4 33.5 18.6 7.2 5.8 17.8 5.0 6.8 3.0 28.0 44.7 7.2 20.4 148.3 10.3 15.3 20.1 29.6 1.8 369.1 0.2 0.0 7.8 7.2 8.3 8.8 0.0 19.1 0.7 22.0 3.5 22.0 11.0 15.1 42.9 15.4 11.1 39.3 7.4 21.9 37.1 3.3 24.4 26.1 18.0 9.6 35.1 57.3 0.5 206.3 25.8 9.2 3.9 9.6 36.0 0.2 10.2 29.3 16.3 CAMK1G "CLICKIII, dJ272L16.1, VWS1" ENSG00000008118 "Calcium/calmodulin dependent protein kinase IG" Q96NX5 1 209583717-209613938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 34.4;ovary: 29.2" "Group enriched" "Detected in some" 6 "Peritubular cells: 6.3;Sertoli cells: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.6;hTERT-RPE1: 6.9;SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (5.17e-2)" "unprognostic (9.64e-2)" "unprognostic (1.73e-1)" "unprognostic (1.49e-3)" "unprognostic (2.56e-2)" "unprognostic (1.93e-1)" "unprognostic (6.79e-2)" "unprognostic (3.98e-1)" "unprognostic (3.59e-3)" "unprognostic (8.55e-3)" "unprognostic (3.17e-2)" "unprognostic (1.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.27e-1)" "unprognostic (9.10e-2)" "unprognostic (3.43e-2)" 0.7 3.5 7.5 0.9 34.4 1.0 0.7 1.3 27.8 1.1 0.8 0.7 1.2 0.8 1.8 6.1 0.6 0.9 1.5 0.6 10.9 9.2 6.9 0.9 1.2 0.8 3.6 17.7 29.2 1.3 0.6 2.0 2.8 3.9 4.6 0.8 0.6 0.6 7.4 0.6 0.6 0.8 2.3 0.9 6.1 0.7 1.4 2.7 0.0 0.7 0.0 0.8 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 1.9 0.3 0.8 0.2 0.0 0.1 0.0 0.0 0.7 0.1 0.2 0.0 0.0 1.2 0.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 11.6 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 1.6 0.0 0.0 0.2 2.0 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 34.4 1.3 27.8 10.9 9.2 3.6 17.7 3.9 2.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 6.3 0.3 0.0 6.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 CAMK2A "CAMKA, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "brain: 105.7;skeletal muscle: 50.1" "Cell type enhanced" "Detected in some" 20 "Basal keratinocytes: 3.1;Cardiomyocytes: 11.0;Fibroblasts: 2.8;Melanocytes: 3.3" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 6 "amygdala: 60.7;basal ganglia: 50.6;cerebral cortex: 99.6;hippocampal formation: 74.6;olfactory region: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.7;SCLC-21H: 9.6;SuSa: 2.6;U-87 MG: 8.1" "Group enriched" "Detected in all" 4 "amygdala: 1311.6;basal ganglia: 698.1;cerebral cortex: 1576.4;hippocampal formation: 1569.1" "Low region specificity" "Detected in all" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 21000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 1.3 1.7 60.7 1.3 50.6 1.3 1.1 1.4 105.7 1.8 1.3 3.7 0.0 1.2 2.1 1.4 1.9 1.7 1.3 3.7 74.6 10.5 1.6 1.2 1.5 1.2 5.1 39.8 1.3 1.1 1.1 0.4 1.3 2.4 1.6 1.3 0.0 1.2 1.4 50.1 1.6 1.3 2.5 1.7 1.2 1.3 1.2 2.3 0.0 1.2 0.0 1.1 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.5 1.3 0.8 0.7 0.0 0.1 0.0 0.2 0.6 0.1 2.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.2 1.7 0.0 1.1 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.0 9.6 0.0 0.1 0.2 0.3 2.6 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 8.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 60.7 50.6 1.4 99.6 74.6 10.5 5.1 39.8 2.4 2.3 0.0 0.0 0.0 0.0 3.1 0.1 11.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.4 0.8 0.0 0.0 1.1 0.0 0.2 1.3 0.2 0.0 0.0 0.0 CAMK2B "CAM2, CAMK2, CAMKB" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;heart muscle: 39.2;skeletal muscle: 70.7" "Cell type enriched" "Detected in many" 11 "Bipolar cells: 838.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 680000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 1.4 8.1 20.6 1.4 46.7 1.2 2.0 60.1 81.9 1.2 1.4 4.0 0.7 1.7 1.3 18.8 2.0 1.8 1.2 39.2 36.5 18.0 1.7 3.5 1.2 1.8 10.3 21.3 1.1 3.3 5.6 9.9 1.1 13.4 3.0 1.4 2.7 1.8 2.2 70.7 1.8 1.6 1.2 4.1 1.3 2.4 2.3 4.8 0.0 7.7 2.4 2.0 1.1 0.0 1.3 1.0 3.2 1.2 3.2 1.2 0.8 0.0 0.3 0.2 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.9 0.2 0.1 0.1 0.2 0.8 0.0 1.1 2.4 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.2 0.1 0.0 2.4 0.1 0.9 0.1 0.0 0.0 42.0 2.2 0.2 0.0 0.0 0.1 1.9 0.2 0.2 0.2 0.4 0.2 0.0 0.5 0.4 0.1 0.2 0.0 0.2 3.2 0.7 1.0 0.8 0.9 1.2 1.1 1.0 0.5 0.5 1.3 1.2 1.1 2.0 3.2 1.2 1.0 0.9 0.8 20.6 46.7 60.1 42.4 36.5 18.0 10.3 21.3 13.4 4.8 0.0 0.0 0.0 27.8 1.0 838.1 74.9 2.5 0.0 0.0 0.0 43.2 0.0 8.3 0.0 0.8 0.6 0.0 0.0 0.0 0.1 0.4 2.6 4.6 4.4 0.2 57.2 39.0 0.0 1.2 2.1 1.7 0.0 1.7 0.0 0.0 14.1 0.1 0.0 0.0 0.8 46.7 0.0 0.9 0.0 1.7 0.4 0.2 0.0 0.0 0.7 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 140000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 22.8 12.9 47.7 18.3 13.0 2.8 23.5 50.2 30.6 11.0 18.2 7.4 28.6 13.6 11.6 9.4 15.6 9.6 14.8 77.1 17.9 21.4 9.6 17.6 14.7 17.5 14.0 23.8 12.9 7.4 33.7 7.0 9.3 12.5 16.3 19.0 9.9 9.4 48.3 48.5 10.8 19.2 26.2 16.0 8.4 17.6 9.4 8.5 11.2 11.6 9.8 14.5 21.5 22.6 18.5 11.2 0.6 8.8 6.4 9.7 5.2 1.0 14.5 16.1 5.4 35.2 67.4 5.7 34.1 22.8 13.4 11.6 9.8 4.1 20.9 5.0 23.7 17.0 0.5 10.0 5.3 13.7 8.0 2.5 0.0 5.3 11.2 17.9 0.0 0.0 43.0 7.3 10.4 25.8 21.3 11.9 2.6 0.8 9.3 25.3 3.9 2.1 0.8 2.3 13.9 5.4 4.0 18.9 0.1 13.7 9.9 4.3 4.4 4.6 6.9 4.6 14.0 0.1 5.6 7.1 35.5 8.4 15.1 6.7 7.3 3.6 17.9 18.3 1.3 16.7 0.0 8.8 0.0 5.1 5.1 9.7 8.0 5.0 5.6 11.2 18.5 5.8 4.9 0.6 6.4 1.7 0.0 9.3 5.2 47.7 13.0 50.2 25.6 17.9 21.4 14.0 23.8 12.5 8.5 38.7 29.9 22.6 16.0 16.4 72.0 243.3 58.6 20.1 28.4 27.9 82.5 0.4 5.0 6.4 2.9 29.8 57.0 0.0 17.5 0.4 34.7 31.3 9.3 49.4 15.8 68.3 99.5 19.6 16.8 4.5 18.7 21.0 5.0 2.8 82.1 41.3 11.4 45.6 18.7 17.7 71.5 6.5 33.3 2.9 4.4 27.9 0.9 17.5 41.1 16.3 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 94.2;Cytotrophoblasts: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Cell line enhanced" "Detected in all" "PC-3: 46.3;SK-BR-3: 58.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 11.1 8.0 7.3 13.9 5.3 8.7 8.6 7.6 13.2 10.6 8.7 12.5 12.0 8.2 8.1 9.8 4.1 17.4 5.7 6.5 8.4 7.5 6.8 5.6 6.2 5.6 2.6 7.6 9.5 4.6 5.9 10.5 7.3 16.3 9.0 10.6 6.1 12.4 5.8 7.8 12.7 11.4 5.3 6.8 46.3 11.6 7.6 4.3 5.5 16.2 3.8 8.8 4.4 58.3 3.7 5.6 10.9 4.8 11.0 7.9 12.7 4.2 10.3 3.8 4.5 7.7 8.4 21.9 2.8 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 14.9 9.4 11.5 7.6 8.4 55.8 6.1 15.3 6.7 9.1 7.0 94.2 130.5 11.6 10.6 1.9 18.0 50.5 0.0 17.2 36.6 11.5 7.3 16.1 7.8 22.8 25.4 23.0 12.3 13.6 2.3 11.8 10.5 11.8 5.4 20.0 16.3 16.9 51.8 17.7 27.0 74.1 45.3 50.6 0.5 10.6 11.0 67.9 22.4 26.2 10.7 CAMK4 CaMK-GR ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9;lymphoid tissue: 71.7" "Cell type enhanced" "Detected in many" 27 "Bipolar cells: 47.8;Early spermatids: 236.0;Late spermatids: 80.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 14.1;memory CD4 T-cell: 10.3;memory CD8 T-cell: 7.8;naive CD4 T-cell: 19.8;naive CD8 T-cell: 10.9;T-reg: 11.3" "Lineage enriched" "Detected in single" 26 "T-cells: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 39.4;JURKAT: 27.3;MOLT-4: 12.0;SH-SY5Y: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 1.1 6.5 9.5 6.4 34.2 4.6 1.0 48.9 16.5 1.8 2.3 1.0 0.0 2.4 1.3 0.8 1.4 0.9 2.7 0.9 5.9 3.2 1.4 2.5 1.9 12.0 2.3 6.8 1.4 0.9 0.3 1.3 0.6 3.4 5.8 2.5 0.1 1.7 2.6 0.8 0.9 3.8 1.5 2.0 4.2 2.6 13.8 6.6 71.7 1.0 0.0 8.1 2.8 1.1 0.7 0.0 0.4 0.0 0.6 19.8 3.4 0.0 0.0 1.4 0.9 0.3 1.1 0.0 0.3 3.0 3.6 3.6 0.0 0.0 0.0 1.9 0.1 2.4 0.1 3.0 0.3 2.6 39.4 2.4 0.5 1.3 0.0 0.1 0.2 0.1 0.1 0.0 7.6 0.8 2.2 0.6 27.3 0.0 1.4 0.2 0.0 12.0 0.0 1.8 0.0 0.1 1.8 2.3 0.1 1.3 0.0 8.6 15.4 0.5 0.0 2.6 0.1 0.0 0.2 0.0 7.5 4.4 0.0 6.6 1.2 0.1 0.0 3.6 0.0 2.8 0.0 0.0 0.0 2.8 0.0 14.1 0.7 10.3 7.8 0.0 0.2 19.8 10.9 0.4 0.6 0.0 0.0 11.3 3.4 9.5 34.2 48.9 15.1 5.9 3.2 2.3 6.8 3.4 6.6 0.0 0.6 4.2 0.2 1.0 47.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 236.0 0.7 0.0 0.0 0.0 0.1 1.6 0.4 4.6 0.2 0.2 0.0 0.0 0.6 1.0 80.4 3.7 1.1 0.0 0.0 0.1 2.1 0.8 0.0 1.4 0.0 4.1 0.0 4.5 3.2 6.1 0.9 0.0 29.9 0.0 0.3 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.9;salivary gland: 27.1" "Cell type enhanced" "Detected in many" 9 "Bipolar cells: 36.4;Rod photoreceptor cells: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 18.2;U-87 MG: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol No No Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 4.3 10.2 15.3 5.1 21.4 3.7 4.7 23.2 38.9 4.1 3.2 2.2 4.0 3.1 7.5 5.2 4.2 3.7 3.8 5.7 13.8 6.8 1.5 1.0 4.0 2.5 5.5 16.0 6.0 7.5 5.0 10.1 2.3 11.2 3.3 3.1 2.5 27.1 11.2 2.2 7.8 3.7 6.2 2.2 4.3 2.9 6.1 5.0 1.7 7.2 2.3 2.5 5.6 4.9 0.1 1.6 5.6 4.1 0.0 1.0 1.1 4.9 8.5 0.9 4.3 3.1 5.5 0.3 3.4 3.7 3.3 1.5 3.1 1.5 3.0 3.7 6.6 3.4 14.7 2.3 4.2 2.0 0.1 7.8 3.4 18.2 1.1 3.1 0.5 2.7 4.2 3.6 6.2 2.1 2.9 1.5 4.4 2.6 0.1 1.6 1.3 4.1 1.9 1.0 7.2 8.1 2.1 3.7 3.4 3.5 3.1 5.0 2.8 1.3 10.2 2.2 0.5 3.9 1.1 2.0 5.7 7.7 7.3 2.8 0.4 0.2 0.1 20.8 2.9 0.7 0.0 1.8 3.6 0.6 3.9 1.0 0.0 0.6 0.5 1.6 0.1 0.6 0.3 5.6 0.0 4.1 0.8 0.0 1.1 15.3 21.4 23.2 38.9 13.8 6.8 5.5 16.0 11.2 5.0 6.0 15.1 8.5 1.9 3.3 36.4 5.7 0.0 1.4 5.7 1.8 15.7 0.2 0.0 0.4 0.0 4.4 0.5 0.0 1.4 0.1 4.5 1.4 16.2 0.2 3.8 7.9 4.1 3.1 1.9 0.4 1.1 3.6 8.5 0.0 1.4 3.8 0.8 0.0 1.1 0.0 24.1 0.0 2.0 0.1 1.4 4.6 0.2 0.7 2.3 0.8 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237691-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 125.5" "Cell type enhanced" "Detected in many" 5 "Horizontal cells: 58.8;Late spermatids: 64.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 125.5" "Group enriched" "Detected in many" 5 "classical monocyte: 14.2;eosinophil: 26.1;intermediate monocyte: 19.4;myeloid DC: 7.2;neutrophil: 17.2;non-classical monocyte: 16.5" "Group enriched" "Detected in all" 5 "dendritic cells: 7.2;granulocytes: 26.1;monocytes: 19.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 11.7 6.5 19.7 7.8 30.2 13.8 8.8 125.5 45.5 9.0 9.5 7.1 2.6 12.8 8.6 5.3 8.3 11.8 6.3 6.9 11.2 5.1 7.1 8.9 9.6 6.9 6.2 17.3 10.5 5.8 6.4 4.1 7.5 9.1 12.2 9.7 6.2 7.5 13.2 5.1 9.1 13.2 10.3 6.2 14.1 7.6 3.6 5.8 5.2 6.1 4.5 7.2 7.2 7.4 2.2 7.2 26.1 19.4 3.6 2.2 6.3 12.5 9.4 7.0 13.5 21.1 19.7 10.7 10.4 11.0 8.5 7.8 9.8 5.4 19.4 8.7 21.0 6.0 10.4 8.6 11.2 6.7 13.3 16.9 9.6 6.3 9.6 14.3 21.9 9.2 12.7 16.6 8.0 18.2 11.5 19.9 14.8 11.1 10.5 8.2 12.1 24.3 18.0 5.1 10.5 10.7 15.8 8.2 17.2 8.2 14.0 26.9 10.8 13.6 7.3 8.6 5.9 18.2 26.8 14.5 7.0 5.7 5.9 5.7 40.3 23.9 14.7 13.1 15.4 6.9 0.7 14.2 26.1 2.1 19.4 2.2 2.2 1.7 1.9 7.2 1.2 1.5 1.7 17.2 3.6 16.5 1.6 1.3 6.3 19.7 30.2 125.5 45.5 11.2 5.1 6.2 17.3 9.1 5.8 8.9 3.5 4.1 5.1 7.0 21.6 7.0 20.4 8.1 6.8 8.7 2.0 7.4 3.3 8.7 15.7 17.5 18.2 0.0 9.0 6.7 12.5 10.8 5.8 18.3 7.1 58.8 33.0 12.9 13.9 64.8 19.0 13.7 8.5 15.4 15.9 5.1 7.5 11.5 29.7 8.4 6.4 19.4 21.3 0.7 2.4 5.3 2.9 7.1 15.6 5.8 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871513-10923070 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 64.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073, HPA069313" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA Nucleoplasm "CAB032961: AB_2068446, HPA043561: AB_2678554, HPA048073: AB_2680250, HPA069313: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (8.37e-4)" 12.2 8.8 12.3 12.6 16.1 13.2 9.6 12.5 17.7 15.8 14.0 9.3 9.0 11.5 19.6 9.1 20.5 14.8 12.4 14.7 11.2 7.2 9.3 14.5 8.9 12.4 7.8 10.2 13.0 16.9 8.2 6.9 15.3 9.5 12.6 10.2 12.0 11.4 13.2 64.3 12.5 12.0 15.6 6.6 9.8 11.1 17.5 8.6 9.4 10.0 12.7 15.6 15.8 15.9 1.3 1.6 0.3 1.4 0.1 2.6 0.4 22.6 16.9 24.2 32.8 20.2 27.7 23.2 16.3 28.3 24.2 23.3 26.0 8.3 31.2 19.6 28.4 12.2 21.7 24.7 24.5 15.3 34.9 20.1 9.6 11.0 31.5 17.3 14.4 12.5 18.9 16.0 16.5 20.0 13.8 30.6 24.9 22.9 28.1 14.2 40.9 25.1 12.4 29.9 15.2 28.1 35.1 12.4 36.3 14.6 11.7 17.6 16.9 11.6 14.1 15.7 12.6 14.1 12.4 18.3 29.2 16.5 27.7 19.0 27.4 21.6 27.3 19.2 23.2 12.6 0.0 1.4 0.2 1.2 1.4 0.5 1.3 0.9 2.6 1.3 1.3 1.0 0.9 0.3 0.1 0.7 1.6 0.8 0.4 12.3 16.1 12.5 17.7 11.2 7.2 7.8 10.2 9.5 8.6 8.9 13.5 11.5 4.9 6.9 31.0 0.8 17.8 8.1 6.8 8.7 49.1 16.3 6.6 11.8 25.6 5.7 28.0 46.7 16.9 26.3 10.3 10.9 1.1 23.7 22.3 42.9 26.5 11.1 17.8 13.0 26.2 7.5 5.0 28.9 25.6 10.2 20.3 25.9 18.0 7.3 19.9 6.5 9.2 25.8 16.4 6.0 10.1 4.1 21.2 9.0 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923645 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.3" "Lineage enriched" "Detected in many" 11 "granulocytes: 26.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 9.1 15.9 13.9 18.8 12.7 9.8 13.2 14.2 15.7 11.1 22.1 20.0 7.1 27.1 12.2 13.7 17.2 9.9 16.0 7.0 12.1 12.8 14.6 10.8 10.3 13.6 16.3 8.5 13.9 14.2 11.1 9.8 13.4 11.9 10.7 23.8 10.4 15.9 7.7 5.8 12.8 32.9 12.1 10.1 9.6 16.2 2.9 14.3 30.9 9.3 8.1 14.0 11.8 13.1 0.6 0.3 26.3 0.8 2.4 2.3 0.3 10.9 14.0 13.4 8.0 9.1 7.4 4.3 9.6 8.0 5.6 5.2 30.1 17.9 0.1 4.9 11.9 10.2 22.0 14.7 9.8 9.4 9.7 8.2 0.0 12.6 10.6 9.4 1.7 1.5 8.4 26.9 10.7 13.7 11.3 4.6 6.4 0.8 8.5 12.2 12.8 3.1 0.7 12.3 15.8 9.1 5.1 33.0 5.2 12.7 23.8 12.3 6.5 18.0 7.2 5.5 22.6 7.7 0.3 5.3 10.5 10.7 9.0 5.3 3.3 2.1 3.7 10.3 1.2 6.7 26.3 0.8 4.8 0.5 0.7 0.5 0.4 0.6 0.8 0.2 0.6 0.7 0.7 1.1 2.4 0.4 0.3 2.3 0.3 13.9 12.7 14.2 14.2 12.1 12.8 16.3 8.5 11.9 14.3 11.9 14.8 0.9 33.3 29.0 40.5 6.5 10.2 20.1 14.8 7.0 21.6 1.6 43.1 13.2 0.8 10.8 22.7 0.0 12.7 0.7 17.5 19.6 0.0 13.0 16.2 47.7 13.3 4.9 3.5 0.2 9.2 6.8 10.1 0.0 30.6 11.9 17.9 28.1 8.9 17.0 26.0 19.4 14.4 1.6 1.9 28.4 1.4 12.5 36.5 26.9 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206276-119313926 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Supported Cytosol NA NA Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 9.9 5.5 9.1 17.0 11.1 11.1 8.8 10.7 12.0 6.2 7.5 8.7 3.0 5.7 9.9 5.3 7.5 7.4 6.3 5.9 8.0 9.6 5.5 4.0 10.3 16.3 8.1 6.9 6.3 5.6 16.6 4.1 9.1 9.3 5.3 7.5 6.4 5.4 7.1 3.9 7.4 8.6 10.6 8.9 13.3 7.3 32.3 5.1 40.9 6.0 5.5 15.6 7.6 7.7 1.8 3.3 11.8 3.7 0.6 1.9 1.0 6.3 4.8 16.9 10.6 5.1 6.0 10.0 6.9 7.2 6.7 6.6 10.3 7.9 15.1 6.2 8.7 13.8 9.3 11.6 5.9 14.7 8.6 2.7 15.5 3.7 3.1 6.2 18.0 17.7 5.3 6.5 17.0 18.4 7.1 16.5 14.8 12.5 6.3 12.0 6.9 9.6 10.1 8.8 5.7 5.4 10.4 8.5 2.8 5.9 5.1 2.3 7.1 12.8 5.6 4.6 12.1 5.8 15.2 13.7 10.4 7.4 7.2 9.0 2.1 3.1 12.3 4.2 15.6 7.4 0.8 3.2 2.4 1.3 3.7 1.1 1.8 1.6 1.3 3.3 1.8 1.8 1.9 11.8 0.6 3.1 1.8 1.4 1.0 9.1 11.1 10.7 12.0 8.0 9.6 8.1 6.9 9.3 5.1 8.9 8.8 18.8 4.9 16.0 12.4 5.9 7.6 1.4 4.5 10.4 43.2 5.2 1.7 5.8 22.7 17.8 6.3 0.0 5.8 8.0 8.0 6.2 3.5 2.6 15.0 12.7 8.1 19.0 52.9 32.8 7.2 29.9 15.1 5.4 4.3 17.5 8.7 8.6 12.0 3.1 33.8 25.8 17.6 38.1 26.2 19.2 5.8 20.0 4.5 9.5 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 38.4 9.0 3.7 19.5 4.9 15.5 16.3 24.4 3.8 13.7 18.7 5.9 7.7 9.3 13.8 12.2 8.3 12.5 13.4 27.5 3.8 4.8 7.4 6.7 16.3 19.1 4.4 1.9 17.7 6.8 3.4 13.5 25.4 7.9 12.9 8.0 11.6 9.1 6.3 10.3 8.5 13.8 25.6 5.7 16.4 12.4 9.2 5.2 11.6 13.5 7.0 18.0 24.9 24.1 5.1 3.1 2.8 2.1 10.3 9.9 1.6 1.6 2.3 7.7 3.8 8.9 9.0 5.0 5.8 2.9 1.7 2.7 2.9 2.0 3.6 4.0 3.0 2.7 2.9 1.0 1.0 2.1 2.8 2.9 2.0 12.0 1.9 13.1 1.4 1.5 8.6 3.1 4.5 12.3 6.4 5.6 3.7 2.1 11.7 3.6 2.1 2.0 0.9 2.7 2.0 3.3 4.2 2.3 0.6 4.1 7.4 6.0 6.5 6.8 0.8 8.9 5.6 1.7 2.9 3.1 23.9 2.0 3.2 1.4 6.6 0.6 5.7 6.4 1.2 1.5 0.7 1.5 2.8 9.9 0.9 8.8 2.2 5.1 5.6 1.3 5.1 4.4 8.0 1.0 10.3 2.1 3.1 5.6 1.6 3.7 4.9 24.4 3.8 3.8 4.8 4.4 1.9 7.9 5.2 14.9 6.7 21.6 6.8 9.6 44.8 39.9 0.0 10.7 6.8 12.2 25.5 8.9 5.0 6.0 27.4 22.6 8.7 0.0 6.9 53.5 21.6 9.6 8.1 6.7 12.2 3.2 12.1 39.3 11.3 9.0 6.9 10.4 15.1 5.4 16.2 7.4 11.7 7.0 10.3 3.1 27.4 6.5 19.9 9.8 15.8 6.0 38.0 52.3 10.7 3.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800634 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 66.8" "Cell type enhanced" "Detected in many" 8 "Enterocytes: 105.9;Pancreatic endocrine cells: 67.6;Paneth cells: 84.2;Undifferentiated cells: 54.6;Urothelial cells: 56.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 19.0;BEWO: 13.1;CACO-2: 12.9;CAPAN-2: 26.3;HaCaT: 18.4;HBEC3-KT: 16.0;hTCEpi: 12.3;OE19: 16.9;RT4: 16.0;SK-BR-3: 14.6;T-47d: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.0 0.5 8.5 0.2 0.0 4.8 0.1 0.4 4.4 39.5 0.1 3.2 29.5 1.7 1.7 22.0 1.4 18.8 0.1 0.6 0.0 4.9 15.1 1.3 0.1 0.1 0.3 0.8 18.1 0.9 0.7 4.1 0.2 6.9 6.9 0.5 11.4 5.2 0.1 20.8 66.8 0.4 0.1 0.1 10.2 1.6 0.1 0.5 1.9 13.2 15.7 7.6 8.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 12.9 26.3 0.0 0.0 0.0 0.0 18.4 0.0 16.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.9 0.0 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.0 14.6 0.0 0.1 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.4 0.6 0.0 0.1 0.3 0.2 0.1 0.0 1.6 0.0 28.6 13.4 0.0 0.2 5.1 5.3 11.4 7.0 0.0 4.6 1.7 37.5 0.0 0.1 105.9 0.0 42.7 1.3 0.4 14.4 0.0 8.5 0.3 0.0 16.7 0.0 0.0 0.0 0.0 0.9 0.0 1.0 35.8 0.0 67.6 84.2 0.0 9.9 0.0 0.0 0.4 0.0 1.7 22.5 2.1 0.7 54.6 56.4 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743697-107761667 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 15.8 12.0 11.7 13.6 20.0 38.8 16.8 18.7 19.4 15.3 17.2 19.2 11.6 10.8 22.9 9.7 14.4 14.2 10.2 11.5 11.9 10.7 11.6 12.5 12.9 16.5 12.6 14.3 18.2 15.5 14.5 17.2 13.5 16.5 18.7 13.0 14.7 12.8 19.6 32.6 16.6 14.4 16.2 15.1 15.8 14.7 21.1 13.3 29.0 15.8 11.8 19.3 17.6 12.7 17.9 16.7 32.2 15.7 23.4 40.3 20.1 13.7 15.7 12.2 15.5 11.2 9.8 8.3 10.4 10.8 11.6 11.6 10.6 14.0 19.9 15.0 11.6 19.7 9.8 16.8 12.5 16.0 14.2 10.6 16.2 11.6 8.9 13.0 23.9 15.9 10.1 11.7 15.7 17.2 8.8 12.0 14.1 25.5 17.0 11.1 23.5 32.6 16.2 17.5 11.6 10.7 15.2 13.2 20.6 8.8 12.7 13.0 20.3 15.5 22.7 11.3 14.9 7.7 12.2 11.7 18.2 13.1 17.2 15.8 27.6 30.0 32.3 11.2 14.9 15.3 32.2 14.2 23.3 19.0 14.7 28.0 17.9 30.1 21.8 16.7 17.4 20.9 19.6 21.9 23.4 15.7 9.0 40.3 20.1 11.7 20.0 18.7 19.4 11.9 10.7 12.6 14.3 16.5 13.3 17.9 8.3 18.6 13.2 20.9 11.5 14.9 7.6 5.3 10.3 3.5 3.9 9.0 6.6 8.7 7.0 12.0 7.7 0.0 9.4 7.7 8.2 13.2 12.7 9.4 9.1 9.5 16.1 12.9 21.5 3.6 8.6 10.8 18.6 7.2 7.2 6.8 9.1 14.4 11.0 9.2 13.7 19.4 9.9 22.4 13.0 17.3 8.6 19.8 8.4 16.3 CBLL2 "CT138, FLJ25735, HAKAIL, ZNF645" ENSG00000175809 "Cbl proto-oncogene like 2" Q8N7E2 X 22272943-22274461 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 88.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 12.6 9.7 10.9 9.8 13.7 14.2 27.2 14.5 16.4 20.3 13.4 13.2 17.2 9.9 20.4 24.2 17.4 18.8 12.4 33.8 11.1 11.2 31.2 34.4 15.4 11.2 13.4 11.1 49.1 20.6 14.5 12.1 14.4 15.9 18.0 14.5 15.8 14.0 12.3 20.6 14.6 10.0 27.6 15.8 11.3 13.0 9.7 13.9 11.2 35.8 15.3 16.1 33.6 17.7 9.3 13.7 3.5 3.1 4.4 10.7 3.0 6.7 5.5 31.5 30.2 16.1 22.2 25.4 8.2 16.6 12.7 16.9 18.7 7.5 23.4 5.5 6.0 12.9 12.1 21.8 15.6 17.3 6.7 18.5 13.8 5.2 17.6 47.5 25.4 13.0 30.2 26.4 9.1 88.5 15.5 9.6 28.4 16.8 18.6 8.3 10.7 14.7 17.3 18.9 14.7 10.6 18.2 15.6 9.8 13.3 9.9 25.1 26.1 5.7 13.3 37.0 18.2 4.2 18.7 4.0 7.3 9.3 8.7 10.7 8.7 10.9 16.0 2.4 21.5 8.3 3.5 3.1 0.0 6.7 1.1 9.1 9.3 7.4 8.3 13.7 8.4 7.7 10.7 0.5 4.4 1.1 13.7 9.9 3.0 10.9 13.7 14.5 16.4 11.1 11.2 13.4 11.1 15.9 13.9 26.8 25.6 34.4 63.5 51.6 3.2 25.0 56.0 4.0 18.2 22.7 19.6 34.7 87.9 23.7 47.1 18.0 13.1 0.0 33.0 56.8 32.0 34.6 34.6 30.1 15.8 1.6 39.6 16.5 17.5 58.8 47.8 23.1 49.0 8.2 37.0 24.9 27.7 14.0 41.4 71.2 15.5 45.3 24.0 49.1 59.6 35.0 28.5 27.7 41.7 43.6 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34" P49427 19 531712-542092 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 16.5 15.9 21.3 11.3 19.1 24.7 20.4 25.7 30.9 16.0 20.5 19.5 10.5 15.4 13.3 13.4 15.6 14.5 13.6 35.6 21.1 18.2 12.1 36.0 13.0 9.9 18.5 19.8 17.0 37.4 11.3 17.0 24.9 16.2 17.2 10.6 15.3 26.4 18.5 63.9 19.0 13.2 18.6 14.3 12.7 15.7 43.6 15.0 12.2 13.1 17.0 8.7 19.2 16.4 2.9 2.8 11.5 4.5 1.5 4.1 1.3 18.7 18.8 24.1 19.8 10.9 10.5 24.1 16.9 13.0 18.2 19.0 29.0 11.5 10.3 17.7 12.0 11.0 13.0 18.9 14.2 9.3 16.9 50.8 9.5 12.4 31.4 27.3 13.4 11.6 13.5 21.3 15.4 16.1 14.3 21.7 14.6 40.8 20.8 12.0 26.9 18.3 17.9 30.4 13.9 18.2 16.9 12.4 17.4 13.7 11.2 31.4 23.3 14.7 15.2 28.0 20.7 12.2 19.8 17.7 13.3 15.9 30.9 22.5 20.7 15.9 13.8 18.2 19.0 13.7 4.5 3.5 6.2 2.3 3.4 1.7 2.9 3.2 4.1 2.8 1.7 2.5 2.4 11.5 1.5 4.5 2.3 3.1 1.3 21.3 19.1 25.7 30.9 21.1 18.2 18.5 19.8 16.2 15.0 0.0 4.8 9.7 16.8 41.6 35.9 25.8 38.2 1.4 1.2 14.0 23.6 38.5 11.6 17.9 55.3 20.2 34.4 0.0 17.3 40.4 28.2 30.2 0.0 35.2 23.7 15.9 12.7 14.7 12.6 170.3 16.7 12.9 18.6 10.0 25.9 67.6 35.7 21.2 14.2 15.9 36.1 12.9 30.1 18.4 52.8 47.8 52.7 10.0 21.2 26.8 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Horizontal cells: 211.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 17.2 15.2 19.1 8.6 21.1 3.9 14.0 29.2 20.4 21.1 19.3 16.4 13.1 16.9 15.8 9.9 12.3 12.9 16.6 14.1 21.7 17.7 20.8 17.0 11.7 3.5 20.0 16.3 17.4 15.1 29.3 29.6 14.8 19.3 21.1 12.4 11.0 8.4 18.5 11.9 7.6 17.2 27.6 16.6 8.8 25.2 26.7 19.9 0.7 9.8 7.3 2.5 23.4 23.1 0.1 0.7 2.0 0.1 0.0 0.1 0.0 9.5 9.0 9.7 4.5 9.7 12.0 3.4 11.0 15.6 7.6 8.0 7.3 21.8 0.0 11.8 18.2 5.7 4.4 7.1 6.1 9.3 0.0 5.7 7.4 10.8 2.8 11.0 5.9 3.3 8.4 7.9 12.3 12.4 9.5 25.3 5.9 18.7 0.0 12.3 2.6 0.1 1.0 7.9 12.4 8.7 0.0 16.3 0.0 12.2 18.5 7.0 10.2 18.6 7.8 10.9 6.2 10.1 0.3 25.5 13.9 7.3 15.9 14.5 0.0 0.0 0.0 18.5 0.0 18.6 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 19.1 21.1 29.2 20.4 21.7 17.7 20.0 16.3 19.3 19.9 38.7 29.4 1.4 19.9 10.4 96.7 50.6 25.5 21.4 35.2 41.8 111.9 5.2 11.6 22.3 90.9 47.3 45.2 23.3 35.4 6.1 27.8 25.0 6.9 24.5 3.2 211.4 25.3 42.4 7.1 98.3 40.9 6.8 15.1 9.0 24.1 34.1 46.5 54.5 80.2 32.9 64.0 77.6 45.3 40.8 51.3 6.9 1.1 1.3 26.4 26.8 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932379-103057462 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved NA NA 12000 "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favorable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 32.2 22.7 33.1 14.8 33.2 3.1 19.8 30.3 42.1 26.7 21.8 42.3 21.5 26.0 27.0 18.7 28.3 26.0 28.1 30.7 31.4 25.5 23.7 20.1 26.4 7.9 31.2 28.4 29.7 28.8 32.5 25.9 25.6 27.0 25.1 18.2 23.7 23.0 28.8 17.0 23.8 29.6 28.7 24.3 18.3 25.5 21.8 31.0 2.1 26.3 15.9 12.4 25.2 32.6 0.9 0.2 0.0 2.0 0.0 0.4 0.1 13.3 26.7 17.2 12.6 19.2 22.0 17.4 15.3 16.2 16.3 15.0 9.1 15.8 0.0 16.8 29.8 12.4 17.0 17.7 18.3 17.3 16.3 8.0 7.3 21.6 9.1 20.9 0.0 7.9 19.0 18.9 16.7 16.0 17.2 31.5 3.1 5.9 3.8 15.6 28.0 0.1 1.7 8.2 20.9 22.1 0.0 14.5 0.3 20.8 26.3 12.5 13.7 27.2 10.3 11.5 19.1 15.8 4.7 40.1 15.7 10.5 34.5 14.2 4.9 5.3 3.9 17.6 1.6 15.1 0.0 1.4 0.0 0.0 2.0 0.0 0.9 0.4 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 33.1 33.2 30.3 42.1 31.4 25.5 31.2 28.4 27.0 31.0 53.6 30.2 6.9 10.7 12.9 45.3 25.4 28.1 33.5 33.0 52.4 31.4 10.5 3.3 26.7 14.0 32.3 28.4 0.0 19.0 8.9 18.2 22.0 12.7 16.3 11.2 54.0 24.2 30.1 12.0 4.9 30.0 12.3 11.8 10.0 14.9 28.0 31.1 17.3 51.9 13.5 42.2 6.5 19.6 13.7 16.0 15.9 14.1 1.0 20.9 28.8 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823387-64844569 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Club cells: 12.5;Enterocytes: 10.6;Paneth cells: 14.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 19.4" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 19.5;HaCaT: 14.6;MCF7: 19.7;RT4: 12.0;SK-BR-3: 12.1;T-47d: 11.9" "Region enriched" "Detected in single" 4 "cerebellum: 5.9" "Low region specificity" "Detected in single" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 2.7 0.8 2.1 0.5 1.1 3.5 19.4 0.8 2.9 9.1 0.8 6.3 8.2 1.0 8.0 14.3 2.9 10.5 0.5 0.7 0.0 3.5 0.5 4.2 0.7 0.5 0.5 1.5 7.9 7.0 6.5 13.0 2.0 4.4 3.4 1.0 14.3 7.6 0.5 22.4 19.7 1.6 0.8 0.8 8.5 2.5 0.7 1.8 3.9 8.1 7.7 5.4 6.3 0.4 0.0 0.0 0.0 0.2 1.0 0.1 5.6 0.8 0.5 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 7.6 4.8 0.1 2.8 0.0 0.2 14.6 0.9 5.7 0.0 0.2 2.2 0.4 3.1 2.4 0.0 0.1 1.4 0.0 7.2 0.1 0.1 0.0 0.0 2.3 3.8 0.0 0.0 19.7 0.1 1.0 1.8 5.3 0.8 0.8 0.3 2.7 3.4 12.0 10.4 0.5 1.8 12.1 0.3 2.9 11.9 0.2 0.0 0.0 2.1 0.0 0.0 1.4 1.3 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.8 0.5 19.4 0.8 0.7 0.0 0.5 0.5 2.0 0.7 8.9 6.4 0.0 2.3 5.8 0.0 1.6 2.5 6.7 12.5 1.8 0.0 4.8 0.0 1.7 0.5 0.0 10.6 0.0 5.3 4.1 0.6 2.1 1.1 0.0 0.9 0.0 3.5 0.0 0.0 0.4 0.0 0.2 0.0 1.8 3.3 0.9 2.8 14.0 0.0 0.3 0.0 0.0 0.5 1.7 1.1 7.0 5.6 0.0 3.8 2.0 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500893-91525764 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 28.3;Spermatocytes: 28.4;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: AB_2674807" "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 2.5 3.7 5.7 7.6 8.9 15.4 4.3 19.4 10.3 2.5 4.2 1.4 0.9 4.2 2.8 2.6 4.7 1.7 2.6 1.9 6.8 5.2 3.6 2.3 5.1 11.7 4.0 4.7 3.7 2.4 2.2 12.3 7.9 5.2 2.7 6.8 2.3 2.5 2.3 1.0 6.8 4.9 3.3 5.9 15.1 2.6 21.2 4.7 18.7 2.5 4.5 12.0 4.2 3.0 1.6 3.5 0.1 1.6 2.4 6.5 2.1 14.2 4.2 27.6 7.8 0.6 3.7 8.8 5.4 4.3 10.7 11.7 8.9 5.1 9.9 7.6 3.4 9.3 6.2 18.1 6.1 14.8 16.4 15.5 15.0 12.2 4.1 1.0 16.3 5.5 1.9 1.8 9.8 5.6 1.9 4.1 13.9 19.8 14.5 7.3 5.2 14.0 14.6 22.9 7.8 10.1 17.3 22.9 6.3 4.6 10.7 21.9 8.6 17.1 4.7 9.6 7.1 4.4 8.0 3.4 12.1 10.7 9.4 8.1 5.3 6.7 26.5 4.3 15.9 4.4 0.0 1.6 0.0 5.9 1.2 5.2 1.5 4.5 5.6 3.5 1.6 2.5 5.1 0.1 2.4 0.3 2.1 6.5 2.1 5.7 8.9 19.4 10.3 6.8 5.2 4.0 4.7 5.2 4.7 0.0 0.6 2.2 1.1 5.3 7.6 1.3 0.0 1.4 1.2 1.8 0.0 5.3 3.3 1.1 28.3 2.8 0.2 0.0 2.2 5.1 4.6 0.7 4.6 0.0 2.2 3.2 0.0 3.1 1.8 12.9 0.9 1.0 3.3 1.0 1.3 1.3 1.0 1.1 0.7 0.1 4.7 6.5 3.1 28.4 20.6 3.1 1.8 5.1 2.9 0.9 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 88.4" "Cell type enhanced" "Detected in many" 18 "Erythroid cells: 280.4;Extravillous trophoblasts: 116.8;Spermatocytes: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 6.1;T-reg: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;NK-cells: 6.1;T-cells: 5.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003387, CAB003799" Enhanced Supported Nucleoplasm,Cytosol NA Yes Cytosol Nucleoplasm "CAB003799: AB_344898, HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 4.1 2.2 0.8 17.8 2.4 17.8 4.4 0.7 1.6 4.2 6.5 1.1 3.4 6.1 2.9 4.8 19.0 1.5 2.4 2.3 0.9 0.7 3.1 1.7 5.7 15.1 1.7 0.6 2.2 1.0 0.5 4.4 13.3 1.2 1.5 8.3 1.0 3.8 2.9 1.0 4.9 8.3 2.7 2.5 8.3 5.0 13.8 1.2 88.4 1.8 16.7 20.1 3.2 6.9 0.9 1.7 0.0 0.2 6.1 5.7 1.8 48.9 18.6 49.6 19.6 3.2 5.0 20.4 37.0 27.0 45.2 43.6 43.6 43.3 44.9 14.4 10.1 16.6 30.5 33.7 21.5 47.1 31.9 24.6 23.5 18.4 25.3 0.6 36.0 24.3 0.9 2.1 29.2 28.5 10.3 27.1 29.6 35.9 55.3 50.2 13.0 45.3 25.9 21.8 29.6 39.3 39.4 46.2 22.0 17.2 16.3 23.3 20.4 24.9 37.8 19.2 28.1 40.8 22.1 11.1 19.3 41.2 20.3 50.6 21.7 34.8 40.5 16.6 40.4 23.9 0.0 0.0 0.0 0.5 0.2 0.5 0.9 1.5 2.7 0.5 0.5 0.5 1.5 0.0 6.1 0.2 1.7 5.7 1.8 0.8 2.4 0.7 1.6 0.9 0.7 1.7 0.6 1.2 1.2 0.0 2.7 2.2 3.6 35.3 1.0 0.5 0.0 14.7 7.9 17.4 0.0 11.0 3.3 0.7 8.8 4.5 1.7 280.4 0.0 116.8 5.1 1.0 0.0 0.8 46.3 0.0 2.9 9.8 15.3 6.3 2.0 8.8 1.7 1.8 4.0 1.0 0.3 0.0 0.7 2.1 0.5 0.0 1.4 104.2 29.6 16.3 18.4 7.0 5.6 6.0 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 12.3 19.9 16.8 16.4 23.8 17.3 10.1 14.8 21.9 11.1 18.3 8.1 16.4 23.4 12.1 21.7 14.4 14.4 19.4 8.7 15.3 12.6 22.2 33.9 11.8 14.0 13.3 19.4 11.3 22.2 21.6 27.7 13.6 15.8 13.6 12.6 8.1 17.2 8.9 17.5 14.1 20.7 9.0 10.7 15.9 19.0 8.7 13.6 8.0 27.1 10.1 12.1 10.8 14.5 7.8 14.5 3.4 15.3 15.2 13.3 8.8 14.7 9.6 7.7 3.1 3.2 6.1 8.1 12.2 6.9 8.7 2.9 7.4 11.2 13.1 6.2 10.5 5.4 10.3 3.3 17.0 5.5 2.9 8.1 5.1 10.8 0.8 13.4 8.3 9.4 7.5 5.7 5.5 8.3 5.8 15.1 8.7 13.4 1.8 9.9 19.2 10.0 23.8 15.8 16.0 7.3 14.6 10.5 18.4 15.6 11.7 7.6 16.5 15.3 7.1 3.6 9.1 16.7 13.2 13.4 5.9 15.3 6.1 8.3 6.6 3.6 4.0 9.0 14.3 8.4 3.2 11.7 3.4 12.9 15.3 10.9 6.8 11.4 8.9 14.5 7.8 13.3 10.9 1.5 15.2 11.2 10.0 8.8 8.8 16.8 23.8 14.8 21.9 15.3 12.6 13.3 19.4 15.8 13.6 11.9 28.2 16.7 22.2 13.7 17.3 4.8 45.9 18.7 9.1 26.2 23.6 25.3 36.5 23.6 5.0 17.5 42.9 0.0 11.0 16.4 18.6 26.1 9.2 37.6 16.3 17.5 65.1 19.6 16.7 5.4 22.2 13.0 18.6 14.4 38.5 10.3 14.2 35.1 11.7 45.1 33.8 6.5 11.3 23.1 29.8 13.6 23.3 17.5 50.1 18.6 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702730-1724324 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Spermatocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 14.3 14.9 17.2 23.7 26.9 39.7 13.0 35.2 32.7 12.5 16.4 14.3 6.1 29.2 16.5 8.5 12.1 12.6 10.2 10.2 19.4 8.4 11.7 12.5 19.0 20.3 22.6 9.0 16.2 12.9 12.2 27.5 12.9 17.1 14.4 14.6 11.6 12.7 10.3 21.5 15.1 34.9 13.1 26.0 24.2 15.7 16.4 25.1 14.9 14.6 7.6 22.4 13.5 15.2 7.4 11.8 33.5 6.3 4.4 5.5 1.4 16.3 9.9 7.1 6.5 9.4 7.5 7.0 16.1 7.2 8.0 9.4 12.3 15.0 17.4 9.9 4.7 10.4 12.2 6.5 8.4 6.4 13.3 10.6 15.5 18.5 11.0 6.2 17.3 22.4 8.7 5.7 7.0 4.6 9.7 13.8 9.4 18.1 14.6 6.7 9.2 8.0 13.6 9.9 10.0 8.4 14.7 10.8 8.4 6.5 7.4 7.9 11.4 14.1 16.6 19.3 3.6 11.1 7.2 14.0 12.6 12.3 5.6 8.9 20.4 14.8 21.9 4.3 14.0 4.0 16.7 6.3 7.7 5.5 3.4 4.2 6.2 4.7 4.2 2.0 7.4 4.7 4.0 33.5 4.4 3.7 11.8 4.5 1.4 17.2 26.9 35.2 32.7 19.4 8.4 22.6 9.0 17.1 25.1 47.6 54.9 22.4 11.6 12.5 31.1 1.2 12.7 53.5 58.0 14.0 25.5 13.8 8.3 17.1 29.6 20.3 32.5 23.3 13.2 19.0 13.9 10.7 79.0 12.3 10.9 38.1 8.7 11.6 8.2 11.1 32.8 22.6 10.1 23.4 23.2 20.4 21.0 46.0 20.1 9.6 39.2 12.9 9.1 104.7 84.3 12.8 25.5 25.5 18.6 12.9 CDK11B "CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58" ENSG00000248333 "Cyclin dependent kinase 11B" 1 1635227-1659012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Spermatocytes: 147.7;Spermatogonia: 172.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA025061, HPA073626" Approved Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (7.52e-3)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (3.75e-2)" "prognostic favorable (1.14e-4)" "unprognostic (9.75e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "unprognostic (6.04e-2)" "unprognostic (8.45e-2)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (6.52e-3)" 10.5 9.8 10.4 11.7 15.1 24.3 8.6 15.0 14.1 9.0 13.3 11.6 6.7 17.4 11.0 6.1 8.6 7.3 7.5 11.2 12.2 9.3 7.9 8.3 12.8 13.1 11.4 9.7 10.3 11.8 9.1 9.6 8.3 11.0 8.9 7.1 7.0 14.0 9.5 33.7 14.0 18.0 14.0 14.8 12.9 9.6 15.8 13.1 12.2 9.5 8.3 10.3 11.6 11.8 5.2 6.2 16.4 4.2 5.1 8.0 2.1 20.5 16.7 12.8 10.1 12.2 8.1 14.3 20.1 11.1 15.8 13.7 18.7 23.3 19.2 20.0 10.0 10.9 18.8 11.7 11.9 9.3 17.4 20.5 20.2 31.1 16.7 14.2 23.0 24.4 10.0 8.1 14.8 11.7 8.9 12.9 21.1 24.5 13.8 8.2 14.4 22.6 22.3 19.2 8.0 20.6 23.3 21.0 15.3 8.4 8.1 14.5 17.7 19.3 19.9 21.3 7.9 14.9 17.1 17.8 15.5 16.4 10.5 19.3 28.4 25.1 38.8 17.9 27.9 10.7 8.2 4.2 6.3 8.0 3.6 4.1 4.2 5.1 5.4 3.1 5.2 5.9 4.4 16.4 5.1 3.8 6.2 4.1 2.1 10.4 15.1 15.0 14.1 12.2 9.3 11.4 9.7 11.0 13.1 17.9 42.1 36.6 15.2 12.8 30.5 36.0 25.5 42.8 48.9 26.2 19.6 25.0 8.3 26.8 28.9 28.9 89.0 23.3 30.7 26.3 20.4 16.2 52.2 33.4 18.4 14.3 27.6 18.4 25.4 16.7 26.7 23.2 5.0 35.1 53.9 22.7 29.9 56.1 25.1 12.6 42.3 51.8 25.5 147.7 172.1 15.2 37.3 27.7 50.7 12.2 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461511-39564907 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 16.0 13.1 12.4 17.4 9.2 32.4 14.0 23.4 17.8 18.2 17.6 9.6 15.7 11.1 15.7 12.0 16.9 12.2 12.5 11.0 10.1 6.7 10.2 18.5 13.5 15.2 10.9 14.3 17.4 11.3 19.0 12.2 18.4 9.5 12.7 11.7 10.4 15.6 11.1 11.1 17.0 16.5 11.0 10.6 16.3 11.8 18.9 8.3 29.0 15.0 5.4 17.3 16.3 20.5 5.1 4.0 10.4 2.9 6.6 4.0 0.9 8.9 11.1 6.7 6.2 4.9 5.5 6.2 8.1 6.9 11.1 8.3 13.6 5.5 12.7 7.1 8.5 11.3 14.6 13.3 10.2 10.8 8.3 11.4 13.7 7.5 10.5 4.8 18.7 9.6 5.9 7.1 13.5 10.7 4.6 6.7 7.7 23.2 8.4 6.3 4.2 15.3 4.8 7.0 4.4 5.0 10.1 14.4 7.2 4.2 10.7 7.2 4.6 10.3 87.5 7.0 10.1 11.2 8.1 7.2 10.1 8.1 7.0 10.4 6.9 4.9 17.9 7.2 7.9 6.6 10.4 2.9 4.1 4.0 2.2 3.0 2.9 2.5 2.7 1.8 5.1 2.9 2.7 9.7 6.6 1.8 4.0 2.0 0.9 12.4 9.2 23.4 17.8 10.1 6.7 10.9 14.3 9.5 8.3 23.8 26.1 37.7 45.0 57.5 45.4 12.1 35.7 29.4 40.9 36.6 60.9 27.7 11.6 24.4 15.9 29.6 32.0 23.3 23.8 24.7 35.7 62.9 27.8 38.9 23.9 33.4 29.9 27.6 37.0 14.0 34.5 34.5 25.3 27.9 26.9 31.5 36.1 31.6 31.8 12.9 67.7 32.3 33.0 113.1 90.5 60.3 48.7 42.9 28.8 77.9 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39949646-40099580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 16.9 15.3 16.0 29.0 14.5 26.7 20.4 23.3 18.2 16.6 18.3 16.4 14.2 11.3 20.3 17.7 20.9 18.1 20.2 13.6 14.3 11.3 14.7 17.5 19.6 21.9 16.5 15.1 24.2 15.3 26.3 15.3 14.8 12.0 15.5 15.5 14.9 17.6 14.5 19.4 16.7 16.3 16.4 11.5 17.4 14.5 20.2 15.7 31.2 23.1 14.6 21.5 18.5 23.6 14.0 3.9 7.9 3.4 5.0 5.0 1.4 15.7 9.4 16.4 15.6 14.8 14.5 11.3 12.6 13.7 11.6 14.6 9.8 10.9 28.6 7.4 13.2 20.4 19.2 13.4 11.1 17.1 14.0 9.9 12.7 11.5 8.8 14.2 19.3 13.9 8.5 14.9 13.2 17.7 13.3 13.6 13.3 21.4 19.8 12.0 8.1 15.3 13.7 23.7 11.1 11.0 17.0 10.9 11.5 10.9 16.0 11.7 17.0 16.0 34.7 11.4 22.2 14.2 24.1 16.1 16.0 15.3 10.3 17.1 16.4 13.8 23.6 11.7 17.5 20.4 7.9 2.7 4.4 5.0 2.2 3.4 7.6 4.8 3.7 1.5 14.0 4.9 4.9 7.6 5.0 3.4 3.9 4.3 1.4 16.0 14.5 23.3 18.2 14.3 11.3 16.5 15.1 12.0 15.7 41.7 63.7 28.9 17.1 19.1 42.3 25.6 30.6 34.8 47.8 29.6 66.8 11.5 6.6 19.1 10.7 22.5 15.9 0.0 13.4 7.5 19.4 16.3 16.2 20.7 11.6 35.0 18.0 20.3 23.2 7.0 24.2 18.3 13.5 15.4 17.7 26.6 24.2 10.5 16.6 11.1 68.4 6.5 15.6 31.4 31.5 22.8 10.2 22.5 18.8 21.7 CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 16 "Early spermatids: 44.0;Horizontal cells: 163.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 7.5;memory B-cell: 9.8;naive B-cell: 5.3;neutrophil: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 9.8;granulocytes: 7.5" "Cell line enhanced" "Detected in many" "Karpas-707: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA015267: AB_1855249" "prognostic favorable (5.86e-4)" "unprognostic (3.96e-1)" "unprognostic (1.91e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-1)" "unprognostic (4.48e-2)" "unprognostic (3.60e-2)" "unprognostic (3.09e-2)" "unprognostic (2.77e-3)" "unprognostic (2.91e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (2.46e-1)" "unprognostic (2.86e-1)" "unprognostic (4.39e-3)" 8.2 4.7 19.8 7.1 19.4 6.1 8.3 28.6 34.9 10.6 5.2 3.7 0.6 2.7 8.6 3.2 3.1 12.0 11.9 11.5 25.8 15.5 19.8 12.7 9.2 10.9 17.3 17.4 14.9 14.2 3.8 14.2 5.9 22.8 11.3 3.4 4.3 7.7 7.0 5.4 2.7 3.8 7.4 7.0 7.5 7.4 7.2 4.5 0.9 13.1 1.6 11.9 6.9 6.7 9.8 0.9 7.5 0.7 0.1 0.2 0.6 7.1 0.0 14.3 1.8 13.4 13.7 3.3 6.0 5.7 3.7 4.0 0.1 3.5 25.4 0.7 5.9 5.4 2.1 0.7 8.4 7.1 0.0 3.4 0.0 4.7 0.1 6.2 7.2 0.1 9.7 2.1 10.9 3.9 6.1 4.7 0.1 0.1 31.3 7.4 0.0 0.0 2.8 9.0 0.0 3.9 19.5 19.7 19.3 1.9 1.9 3.2 9.2 15.2 0.0 0.3 6.7 1.9 3.6 11.5 15.9 20.4 13.3 9.2 17.7 13.5 18.1 6.0 9.5 15.5 7.5 0.3 0.5 0.0 0.7 0.0 9.8 0.0 0.0 0.9 5.3 0.0 0.0 5.6 0.1 0.5 0.1 0.2 0.6 19.8 19.4 28.6 34.9 25.8 15.5 17.3 17.4 22.8 4.5 17.9 3.2 27.7 7.4 0.7 5.1 11.1 10.2 4.0 13.6 10.4 0.0 0.2 6.6 9.4 44.0 2.1 0.0 0.0 5.8 0.1 12.5 8.3 0.0 9.6 4.0 163.7 1.7 1.3 5.1 27.0 14.4 4.6 5.0 1.0 0.1 8.8 9.4 0.2 14.9 18.1 9.5 0.0 6.6 3.8 6.5 1.1 0.0 0.5 0.0 2.3 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.2;ovary: 9.8" "Group enriched" "Detected in some" 13 "Early spermatids: 23.2;granulocytes: 76.3;Late spermatids: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 52 "basophil: 3.5;eosinophil: 6.9" "Lineage enriched" "Detected in single" 69 "granulocytes: 6.9" "Cell line enhanced" "Detected in some" "BJ hTERT+: 14.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HBF TERT88: 18.6;HMC-1: 35.2;LHCN-M2: 10.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 1.3 0.2 0.1 5.2 0.1 0.0 3.7 0.3 0.1 3.4 2.3 0.1 0.1 0.3 4.1 20.2 1.1 1.0 4.2 0.3 0.1 0.0 0.4 0.1 3.3 0.1 0.1 0.1 9.8 0.2 0.0 0.5 0.1 0.1 2.0 0.7 1.4 0.6 0.3 0.7 1.1 3.0 3.9 0.1 0.1 1.1 2.5 0.1 0.1 0.2 1.2 1.2 1.6 1.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.7 0.0 3.2 14.9 5.6 12.2 0.0 1.5 0.0 0.0 1.3 0.2 0.0 0.0 0.0 18.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 35.2 2.1 0.0 1.5 0.8 0.2 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 2.2 0.0 0.0 0.2 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 76.3 0.0 0.0 0.0 0.0 0.0 0.0 28.0 0.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Microtubules, Cytosol" "Plasma membrane" "CAB016535: AB_785112, HPA000974: AB_2666162, HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 22.0 20.1 32.3 13.9 25.0 26.6 17.6 51.5 49.0 17.2 19.3 15.5 17.0 16.4 14.8 12.8 23.8 18.8 14.1 47.3 29.2 18.0 19.9 12.7 14.0 10.8 22.0 21.1 16.7 18.6 22.8 14.9 18.6 28.5 12.7 14.7 13.7 20.1 16.1 91.2 17.0 15.3 18.2 14.8 12.0 14.7 28.7 12.1 10.4 20.9 36.3 12.6 12.9 12.1 8.5 13.5 8.5 10.7 6.3 7.7 5.7 40.6 31.2 30.0 44.3 22.0 18.9 30.0 19.4 23.9 29.5 22.0 35.1 19.8 9.8 12.4 34.7 54.7 23.1 31.9 41.3 19.9 11.7 50.6 10.6 43.9 27.3 28.6 11.1 24.9 23.6 26.4 41.8 50.5 24.7 26.4 10.3 15.7 16.7 25.8 35.4 9.7 25.6 23.5 15.4 33.8 10.3 23.7 17.1 22.2 32.3 25.4 19.2 52.6 40.7 20.0 36.5 36.3 13.7 26.5 19.8 32.4 30.1 23.1 13.2 12.8 9.5 17.4 52.0 22.1 3.1 8.8 8.5 4.8 10.7 6.2 3.8 6.2 7.7 11.6 8.5 5.6 5.8 4.2 6.3 9.6 13.5 6.0 5.7 32.3 25.0 51.5 49.0 29.2 18.0 22.0 21.1 28.5 12.1 0.0 6.7 15.3 27.9 28.8 24.3 37.2 15.3 4.0 4.5 29.6 3.9 23.1 46.4 30.2 25.1 15.7 50.5 0.0 32.2 31.3 23.1 37.6 5.7 14.8 21.7 28.6 26.9 20.3 19.6 46.6 15.8 10.3 32.1 12.6 30.7 16.0 41.5 33.6 12.4 28.2 12.9 0.0 19.8 18.1 16.8 30.4 21.7 10.2 41.6 53.3 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400560 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 44.5;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 16.3 9.1 20.6 13.9 47.0 31.5 14.7 17.8 35.7 11.8 12.9 23.6 3.4 9.2 20.7 7.5 11.7 10.9 12.9 9.4 25.3 17.3 9.2 12.4 15.9 15.2 23.8 21.0 12.9 8.0 9.9 7.3 24.3 14.8 11.4 9.8 5.7 7.5 9.3 7.3 9.1 9.3 23.4 19.6 15.8 7.9 19.9 28.0 29.6 9.4 6.1 16.6 11.0 10.7 9.6 5.3 29.1 4.7 16.5 14.8 8.6 4.9 4.2 11.0 2.9 5.4 14.3 7.8 11.1 15.7 9.8 9.3 2.5 2.9 7.4 7.7 8.0 5.3 4.5 6.5 6.9 13.4 7.8 5.0 10.6 2.8 3.5 11.7 5.6 6.1 10.3 7.1 14.5 26.2 17.4 44.5 6.3 7.7 6.0 22.1 3.0 5.3 8.8 4.8 2.4 7.3 9.3 5.9 6.3 11.6 4.2 5.7 3.9 6.5 6.1 8.1 8.7 4.6 5.1 53.3 8.7 3.3 4.6 6.0 8.5 6.5 7.9 3.3 2.4 6.4 29.1 3.4 8.9 12.7 4.7 13.7 9.6 10.4 14.4 5.3 8.8 14.8 12.6 12.8 16.5 4.6 3.9 8.1 8.6 20.6 47.0 17.8 24.6 25.3 17.3 23.8 21.0 14.8 28.0 14.9 6.2 24.4 8.9 23.8 10.8 8.9 5.1 9.4 10.3 8.7 15.7 10.0 0.0 4.6 2.7 42.9 6.0 0.0 3.2 25.8 15.5 10.4 17.4 8.9 10.5 4.8 14.5 35.6 15.3 3.2 9.2 9.4 16.9 7.2 7.4 20.2 5.7 3.5 8.9 6.9 9.2 6.5 27.8 6.5 7.6 22.6 11.4 27.7 5.5 11.8 CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504595-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.7;heart muscle: 58.9" "Cell type enhanced" "Detected in many" 12 "Collecting duct cells: 69.8;Paneth cells: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 20.1;HeLa: 17.7;hTERT-RPE1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments" No No "Actin filaments" "HPA045429: AB_10961257" "unprognostic (7.95e-2)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (5.07e-6)" "unprognostic (6.07e-2)" "unprognostic (1.45e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.81e-5)" 2.6 4.3 13.6 2.7 31.8 1.0 2.4 4.2 25.0 7.6 6.9 38.1 20.2 17.3 3.4 4.0 2.7 5.7 6.4 58.9 22.1 16.2 13.7 4.7 6.5 1.9 47.8 16.7 7.5 10.7 3.7 4.0 9.6 22.1 3.1 6.1 5.3 16.5 23.5 3.9 1.6 15.1 4.8 98.7 3.5 9.1 0.9 36.4 0.4 4.8 1.4 2.5 3.7 4.7 0.1 1.4 0.0 2.1 0.6 0.9 0.6 11.7 0.8 0.1 0.6 0.0 0.0 12.7 0.2 2.4 0.5 3.1 5.3 8.8 7.0 1.8 0.1 1.0 10.6 2.6 20.1 0.5 1.9 2.3 1.6 17.7 5.4 2.3 0.0 0.0 1.3 1.0 0.0 0.4 17.2 0.0 10.0 0.1 8.5 0.1 9.5 0.6 0.3 10.0 3.4 0.4 0.9 0.0 8.8 1.9 7.5 4.1 1.6 3.6 1.7 7.8 14.7 7.9 3.4 0.0 0.0 4.8 0.0 0.0 2.4 1.1 1.4 0.1 5.0 2.0 0.0 0.8 0.0 0.1 2.1 0.9 0.0 0.2 0.0 1.4 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.6 13.6 31.8 4.2 19.7 22.1 16.2 47.8 16.7 22.1 36.4 0.0 0.3 0.0 6.7 3.1 4.7 25.0 7.6 0.0 1.2 69.8 0.0 4.9 6.6 15.9 1.6 1.9 20.6 0.0 5.8 1.9 4.8 1.9 0.0 3.9 5.1 0.0 5.8 1.3 1.6 2.8 0.9 3.6 3.3 7.2 12.9 19.1 6.3 98.2 1.4 15.4 1.2 6.5 12.5 1.4 10.0 1.1 1.6 0.5 11.5 5.9 CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 84.5;Late spermatids: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 8.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007053 Approved Approved Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA007053: AB_1233803" "unprognostic (1.66e-2)" "unprognostic (1.84e-1)" "unprognostic (3.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (2.00e-3)" "unprognostic (3.94e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (4.72e-5)" "unprognostic (1.75e-1)" "unprognostic (9.78e-2)" "unprognostic (6.51e-2)" "unprognostic (9.50e-3)" 5.3 3.3 18.1 6.1 29.4 9.7 6.0 13.8 21.3 6.6 6.3 31.1 2.4 4.8 9.6 3.7 7.8 5.3 7.8 4.1 20.8 10.1 6.3 4.6 6.2 8.0 22.1 12.9 9.7 3.1 8.0 4.1 10.5 14.4 25.8 6.1 3.4 4.5 5.9 3.2 7.9 5.9 7.1 20.8 7.0 6.5 16.4 26.3 6.1 5.8 1.3 8.4 5.9 6.4 1.3 1.8 8.5 2.2 1.3 0.8 0.6 3.6 3.9 13.7 16.5 7.4 10.7 7.1 11.9 12.7 4.5 5.9 4.9 4.1 9.3 4.3 8.3 9.0 2.1 5.2 2.5 10.3 11.5 3.0 15.8 5.8 5.7 4.5 6.4 11.9 7.3 5.6 6.1 9.5 11.3 4.4 7.9 4.8 13.0 9.6 5.9 8.6 9.6 1.3 5.2 2.7 9.2 7.0 3.5 5.2 6.7 7.0 13.0 9.0 7.4 10.6 4.8 2.5 23.6 4.9 9.4 5.0 18.9 7.2 1.4 1.9 8.0 9.9 8.7 9.7 3.3 2.2 1.5 0.8 1.2 0.8 1.1 0.7 0.7 1.8 1.3 0.5 0.7 8.5 1.3 0.7 0.9 0.8 0.6 18.1 29.4 13.8 21.3 20.8 10.1 22.1 12.9 14.4 26.3 3.0 16.2 8.1 13.2 8.8 17.3 6.2 12.7 4.0 7.9 15.7 15.7 5.4 1.7 7.5 84.5 11.7 13.8 0.0 4.1 17.1 10.8 49.2 6.9 10.5 14.4 22.3 12.1 14.7 33.3 95.4 10.0 18.4 25.3 3.6 14.2 34.3 6.0 17.5 15.2 5.6 14.1 6.5 8.5 38.1 14.1 14.2 6.6 12.8 12.9 7.4 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966769-55972784 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 78.7;Extravillous trophoblasts: 67.5;Melanocytes: 82.7;Syncytiotrophoblasts: 142.8" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 10.7 7.6 4.5 20.8 6.5 18.7 11.5 4.2 4.3 12.6 11.6 3.5 6.0 6.1 10.7 6.4 13.6 10.8 12.6 10.1 5.4 2.2 8.3 16.7 19.5 12.2 6.0 2.0 14.2 8.3 5.2 4.2 49.0 7.3 10.8 9.1 51.2 9.3 9.9 10.8 14.6 9.3 11.8 5.0 12.5 10.1 7.8 5.1 39.3 9.5 10.7 14.7 16.7 10.1 9.3 10.8 5.2 3.9 4.5 7.6 4.3 16.8 9.1 20.1 11.1 4.1 5.3 37.0 21.0 11.0 26.2 24.5 19.2 16.3 16.1 15.8 7.8 10.5 10.8 15.3 9.2 26.6 18.9 15.0 18.5 15.1 7.3 1.3 14.6 13.4 2.8 2.3 17.7 6.1 7.6 13.2 16.7 17.5 14.7 18.1 13.0 30.3 12.4 8.0 11.5 13.6 29.6 19.3 12.1 7.6 16.6 8.3 10.7 24.0 8.8 107.8 12.0 19.0 10.7 7.3 18.1 17.5 13.9 15.3 8.3 9.6 20.0 10.3 10.7 15.6 5.2 3.6 3.1 7.0 3.9 7.0 9.3 3.2 5.0 2.7 6.1 3.0 5.3 1.7 4.5 1.6 10.8 7.6 4.3 4.5 6.5 4.2 4.3 5.4 2.2 6.0 2.0 7.3 5.1 14.9 3.7 5.2 20.1 24.8 0.0 2.6 12.7 5.3 9.1 1.8 0.0 78.7 1.7 10.5 0.4 15.0 2.1 0.0 5.0 67.5 17.6 10.9 10.4 8.9 11.6 1.6 5.2 8.6 4.8 0.2 13.8 6.3 82.7 47.7 6.3 3.8 9.0 0.0 4.2 3.8 3.4 0.0 14.4 2.9 7.7 27.5 142.8 5.7 6.8 18.0 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Ciliated cells: 25.4;Spermatocytes: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.2" "Group enriched" "Detected in many" 7 "NK-cells: 7.2;T-cells: 5.0" "Cell line enhanced" "Detected in many" "SCLC-21H: 14.4;THP-1: 21.7" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm NA NA Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favorable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favorable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.6 16.2 10.8 2.4 13.0 1.6 4.1 8.7 17.1 8.7 5.0 6.1 5.1 5.3 7.2 6.0 2.8 19.5 5.6 3.0 8.6 10.7 8.2 3.2 4.0 2.0 5.8 14.3 9.5 4.8 7.6 10.8 3.1 9.3 6.1 3.4 7.7 3.6 8.6 2.1 3.6 7.6 5.5 3.1 1.6 3.7 17.7 5.2 0.8 6.8 1.2 1.1 6.3 3.0 0.1 0.8 0.4 0.8 7.2 5.0 1.3 2.4 3.0 2.4 7.6 1.7 2.4 1.0 2.2 4.2 5.9 5.5 0.7 3.6 0.0 3.3 3.6 10.3 3.1 0.0 2.1 2.4 5.9 2.5 0.0 1.9 0.0 7.4 2.8 3.4 1.9 4.4 9.3 3.8 4.6 0.0 5.3 0.3 0.0 1.7 7.1 1.9 0.8 1.9 5.3 1.1 0.0 0.0 0.1 7.4 2.0 14.4 4.1 2.5 3.0 3.6 0.8 3.3 21.7 0.0 2.6 1.0 0.5 2.4 3.8 3.6 0.0 9.3 1.9 2.8 0.0 0.7 0.4 1.3 0.8 0.5 0.0 3.0 1.9 0.7 0.1 5.0 3.2 0.1 7.2 0.7 0.8 2.7 1.3 10.8 13.0 8.7 17.1 8.6 10.7 5.8 14.3 9.3 5.2 3.0 4.1 0.0 1.5 1.9 5.2 2.0 2.5 25.4 5.7 1.8 2.0 3.6 1.7 4.2 4.7 0.5 5.4 0.0 1.3 1.9 3.3 2.5 1.1 0.9 0.9 7.9 0.0 0.6 0.0 1.7 4.0 1.1 0.0 0.0 2.0 4.8 1.5 0.0 6.3 5.3 13.5 6.5 2.3 25.0 2.9 1.9 3.3 0.5 2.9 0.7 CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000906-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" 10 "Basal keratinocytes: 2.4;Distal tubular cells: 1.7;Ductal cells: 1.4;Exocrine glandular cells: 2.0;Melanocytes: 3.3;Pancreatic endocrine cells: 2.0;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007420 Uncertain Approved Cytosol NA NA Cytosol "HPA007420: AB_1078490" "unprognostic (6.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.87e-3)" "unprognostic (6.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-3)" "unprognostic (1.34e-1)" "unprognostic (9.80e-5)" "unprognostic (1.19e-2)" "unprognostic (6.75e-7)" "unprognostic (4.25e-2)" "unprognostic (1.63e-2)" "unprognostic (4.68e-1)" "unprognostic (4.47e-4)" 4.1 3.7 2.7 4.7 2.4 5.5 4.7 4.2 2.4 4.9 4.8 6.5 5.6 5.7 4.0 5.0 4.8 2.6 2.8 3.0 5.9 13.0 5.3 5.5 3.0 6.7 5.9 4.2 8.3 5.0 10.3 5.3 5.2 4.5 0.9 14.7 9.1 4.1 3.9 8.8 5.2 5.6 8.2 5.4 3.8 5.1 1.2 1.8 1.5 1.5 1.7 2.7 1.6 4.2 7.8 11.6 6.1 6.8 8.1 24.2 5.3 3.4 5.9 5.5 6.1 8.9 6.4 4.7 4.6 4.8 9.9 9.3 3.9 3.9 3.3 14.9 13.3 15.5 6.0 5.7 4.6 13.6 7.3 8.6 5.2 4.3 10.6 6.5 4.0 5.9 4.6 3.8 10.9 5.4 20.7 5.8 3.7 8.5 10.0 5.1 5.9 5.5 14.1 8.4 22.6 3.5 11.4 2.6 12.2 15.7 9.5 5.5 16.1 9.5 6.8 5.6 9.6 7.2 6.0 4.9 4.7 3.9 0.0 1.5 0.0 2.1 1.0 0.2 1.2 1.6 1.2 1.8 0.3 2.7 0.5 1.5 1.7 0.6 1.6 2.7 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.0 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 128.1;LHCN-M2: 141.4;RH-30: 445.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497" "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 32.2 43.1 13.8 22.2 15.7 24.0 45.0 13.1 17.9 36.3 28.2 20.1 22.8 15.2 51.4 28.1 29.9 31.0 32.3 27.4 14.5 12.1 24.0 36.9 26.8 26.4 18.3 13.7 61.4 54.4 18.9 34.2 25.0 16.0 37.2 26.9 26.2 29.3 24.1 27.8 25.6 20.7 34.1 13.5 27.2 23.9 24.6 17.5 29.2 54.3 32.1 27.5 33.6 30.9 29.6 25.5 2.6 19.9 15.8 32.1 22.2 9.5 11.1 14.6 13.0 13.4 11.8 9.8 5.5 18.0 24.4 20.2 15.8 9.1 13.9 10.0 8.6 14.4 7.4 20.2 128.1 18.5 6.8 9.3 13.0 7.5 11.1 15.7 14.7 9.0 11.6 9.4 14.9 17.2 16.6 15.6 13.3 13.8 12.0 141.4 13.9 14.1 12.0 17.2 10.0 11.2 12.6 445.0 12.9 7.6 15.1 13.3 12.4 9.8 7.4 14.7 10.5 9.8 17.9 7.1 11.4 10.8 12.9 11.1 6.0 9.7 21.4 10.5 13.7 13.7 1.7 14.3 2.6 26.2 19.9 27.0 29.6 23.1 23.7 21.0 28.1 32.1 28.5 1.2 15.8 12.0 25.5 16.6 22.2 13.8 15.7 13.1 17.9 14.5 12.1 18.3 13.7 16.0 17.5 20.8 25.0 32.0 62.9 79.7 15.3 0.5 48.4 4.0 23.9 45.4 9.8 64.6 59.7 71.7 10.1 44.2 11.3 23.3 53.6 108.9 77.4 41.8 68.1 32.1 111.7 17.5 43.8 34.4 23.2 6.8 59.2 34.0 50.6 54.1 33.5 51.3 55.4 7.0 59.4 66.3 15.3 32.3 54.2 25.9 40.3 75.3 39.1 34.1 78.3 32.5 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053812-151058530 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 4.5 11.3 24.4 6.9 30.4 6.1 5.3 13.6 36.1 5.3 6.1 6.7 4.5 7.9 4.5 17.4 6.5 5.0 6.2 5.8 25.0 19.7 9.0 7.7 5.3 6.0 15.4 15.4 3.2 5.8 8.9 7.9 5.3 20.8 5.8 6.3 3.2 6.0 6.3 5.7 6.5 6.2 6.0 8.6 5.2 5.7 3.1 7.7 6.8 6.0 3.6 6.9 6.7 3.1 6.6 21.5 9.0 21.7 9.5 14.9 10.6 11.7 14.1 13.2 21.5 14.6 10.7 6.6 7.8 12.8 15.3 12.6 10.0 11.0 11.6 27.9 9.6 22.8 8.4 21.2 11.8 7.0 9.1 12.6 12.7 12.4 9.9 9.6 10.2 23.9 11.6 8.9 12.6 3.9 21.4 10.3 18.2 12.9 8.5 15.3 22.7 27.6 21.0 14.5 18.9 22.3 13.5 5.4 12.9 13.3 8.9 8.4 35.9 11.2 13.8 14.7 12.6 6.4 9.0 8.7 15.1 3.9 11.3 14.5 19.7 21.5 4.5 23.7 14.8 27.0 7.8 19.0 9.0 6.9 21.7 5.4 6.6 6.8 6.8 21.5 5.9 5.1 6.2 2.8 9.5 16.4 12.8 14.9 10.6 24.4 30.4 13.6 36.1 25.0 19.7 15.4 15.4 20.8 7.7 0.0 5.9 11.5 6.4 3.2 11.5 3.2 7.6 8.1 7.9 10.4 2.0 20.0 33.2 19.0 0.6 6.3 7.1 0.0 16.6 10.2 6.6 5.0 31.0 9.6 37.8 0.0 8.6 6.2 21.6 0.9 4.4 14.3 10.1 20.8 9.1 11.5 18.7 14.4 10.6 24.0 4.7 6.5 5.0 2.6 9.7 5.5 7.6 8.5 9.6 7.6 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.6" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 219.8;Late spermatids: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 93.5;REH: 45.7" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" 6.6 11.3 6.0 9.1 7.5 22.5 5.9 2.4 6.0 7.8 10.0 9.6 5.7 7.5 6.0 5.9 8.5 4.6 7.8 6.6 6.9 4.2 6.5 7.5 7.3 7.4 7.0 5.2 5.0 10.0 25.7 4.2 20.5 7.5 6.1 9.2 4.4 10.9 6.1 2.0 11.6 9.4 9.8 7.5 6.3 10.8 5.4 8.0 74.6 4.3 9.2 10.3 6.7 9.0 3.6 5.6 6.5 4.8 3.9 7.1 2.3 6.2 2.9 8.0 5.1 2.3 2.6 1.7 6.4 4.0 3.2 3.0 7.8 4.8 4.8 3.7 4.3 2.0 3.8 4.4 9.2 7.6 10.5 3.1 12.0 5.5 7.5 1.4 7.4 0.6 2.6 5.0 4.3 20.4 3.0 1.2 19.6 11.5 13.3 5.7 1.2 93.5 0.8 2.5 7.9 2.6 45.7 28.1 8.1 4.4 0.1 4.2 27.3 0.7 2.2 3.7 6.1 0.1 12.3 4.7 10.5 16.5 4.1 12.9 7.1 0.1 6.4 1.5 25.5 13.9 4.9 1.9 6.5 5.2 3.9 5.9 2.0 5.5 5.6 4.0 3.6 7.1 4.0 1.1 3.9 4.8 5.6 2.8 2.3 6.0 7.5 2.4 6.0 6.9 4.2 7.0 5.2 7.5 8.0 23.8 3.0 11.9 19.5 53.5 0.2 14.8 25.5 4.0 27.3 21.0 0.0 42.7 8.3 31.7 219.8 24.1 11.0 0.0 20.1 3.4 21.6 18.1 24.3 18.4 15.0 0.0 16.1 7.4 23.4 186.0 4.6 21.9 18.6 20.8 46.7 0.5 63.1 14.0 3.2 5.1 0.0 6.5 22.1 2.6 46.4 44.2 14.8 20.3 68.3 23.3 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "Cytotrophoblasts: 97.9;Extravillous trophoblasts: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 7.9 12.9 10.9 6.2 15.2 44.1 14.0 10.8 14.7 9.4 12.7 6.0 6.3 15.8 9.4 8.6 23.4 18.5 16.5 8.1 11.5 9.3 13.8 10.6 10.1 8.8 7.6 9.7 7.7 9.1 3.3 16.2 22.9 11.2 11.2 14.8 6.6 13.2 6.5 15.9 15.4 9.8 12.1 9.2 7.9 13.9 29.0 7.8 12.1 20.0 15.6 15.5 10.7 11.7 15.6 15.0 22.4 11.3 12.4 15.3 7.8 3.6 7.7 1.8 0.5 2.4 11.6 14.7 6.4 7.7 10.7 17.4 16.6 1.9 2.8 10.1 1.7 12.4 2.5 1.4 2.8 5.8 1.3 7.0 0.4 8.1 7.9 0.4 6.7 3.2 14.3 13.8 9.0 2.8 9.4 13.5 15.6 10.3 4.5 4.9 0.7 4.0 14.7 1.7 3.7 7.4 6.6 0.4 1.1 1.6 1.0 0.6 6.5 1.5 5.8 3.4 6.4 11.6 0.6 2.6 0.0 3.2 0.9 5.1 4.8 8.4 3.7 0.8 4.0 0.8 7.3 10.9 22.4 8.6 11.3 14.8 12.4 12.9 15.3 15.0 15.6 11.1 13.2 10.0 12.4 8.0 11.2 12.8 7.8 10.9 15.2 10.8 12.7 11.5 9.3 7.6 9.7 11.2 7.8 14.9 10.4 2.4 16.5 51.3 6.3 8.9 5.1 48.2 10.3 5.2 11.8 97.9 13.3 21.5 6.2 11.3 9.2 0.0 19.0 285.4 10.2 19.9 15.1 6.6 21.2 1.6 2.9 6.7 8.2 3.6 6.9 10.2 6.8 9.0 11.4 9.0 22.5 14.0 6.7 20.7 8.2 25.8 12.2 25.4 15.8 36.6 54.0 9.6 11.8 28.6 CDK8 K35 ENSG00000132964 "Cyclin dependent kinase 8" P49336 13 26254104-26405238 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 55.8;Late spermatids: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044721 Approved Nucleoplasm NA NA Nucleoplasm "HPA044721: AB_2679059" "unprognostic (3.28e-3)" "unprognostic (2.25e-3)" "unprognostic (2.08e-1)" "unprognostic (3.88e-3)" "unprognostic (2.30e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-3)" "unprognostic (2.12e-1)" "prognostic favorable (9.23e-4)" "unprognostic (1.43e-2)" "unprognostic (1.88e-1)" "unprognostic (6.37e-2)" 7.6 8.8 10.1 10.4 8.5 5.2 5.6 26.9 11.3 5.9 24.0 6.0 13.8 13.8 11.2 6.5 10.0 7.0 11.2 7.6 8.3 7.3 9.4 10.4 6.7 5.2 7.8 7.9 6.1 12.7 8.4 10.2 10.6 8.2 7.8 11.2 4.6 9.0 19.2 9.7 6.1 15.0 12.7 6.0 6.4 11.7 16.3 9.9 12.8 6.4 6.9 7.2 15.5 11.0 1.9 1.7 3.4 1.6 1.0 2.1 1.3 6.9 5.7 11.6 11.8 6.2 7.6 7.2 13.4 9.2 10.0 7.2 16.6 9.7 7.4 5.9 6.9 8.0 8.6 13.3 9.0 12.6 17.1 7.4 14.1 4.6 5.7 4.3 22.0 8.1 5.5 8.7 7.5 12.7 5.5 7.3 12.1 21.8 0.0 9.0 7.4 16.8 10.3 9.2 10.5 7.1 10.6 11.5 5.1 5.8 6.5 9.9 5.8 5.7 10.9 9.8 9.6 3.9 10.1 7.4 6.4 8.2 11.7 7.3 5.7 10.1 13.6 4.0 9.3 7.6 0.4 0.9 3.4 1.1 1.6 1.9 1.0 1.5 2.1 1.7 1.9 2.1 1.7 0.0 1.0 1.2 1.0 0.6 1.3 10.1 8.5 26.9 11.3 8.3 7.3 7.8 7.9 8.2 9.9 8.9 4.1 4.5 6.7 17.5 19.1 5.0 7.6 0.0 5.7 1.8 23.6 7.2 8.3 8.5 55.8 6.8 9.7 0.0 7.2 8.3 9.3 11.0 0.0 5.4 7.1 17.5 8.1 6.2 7.5 83.1 7.2 6.6 8.5 8.2 7.8 7.1 10.6 11.5 7.8 11.5 16.6 6.5 11.3 27.8 17.5 20.8 8.1 6.9 10.5 9.1 CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" NA NA Nucleoplasm "Cytoplasmic bodies" "CAB004216: AB_627245, HPA006738: AB_1078493" "unprognostic (3.60e-1)" "unprognostic (1.71e-1)" "unprognostic (5.44e-3)" "unprognostic (1.04e-3)" "unprognostic (1.93e-1)" "unprognostic (3.97e-2)" "unprognostic (2.07e-1)" "unprognostic (5.84e-2)" "unprognostic (2.66e-1)" "unprognostic (8.36e-2)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (3.52e-2)" "unprognostic (8.78e-3)" 26.2 27.0 22.8 18.9 22.4 33.9 17.4 31.0 26.8 23.1 21.9 22.9 24.7 16.6 22.5 20.1 22.7 29.1 21.5 22.9 26.3 23.4 18.5 48.7 23.3 26.6 23.4 18.8 43.7 29.1 15.5 28.4 19.8 20.6 20.7 10.8 18.7 20.6 21.6 14.6 26.6 21.4 21.0 17.9 29.0 17.7 22.3 16.1 29.3 25.8 18.3 24.2 17.0 17.6 6.0 8.9 5.1 6.4 18.6 9.9 2.9 9.0 16.4 10.3 11.3 11.7 9.2 13.5 9.3 13.7 9.7 8.8 12.2 10.2 15.9 10.9 10.5 13.4 18.3 6.8 15.2 3.7 14.2 8.1 14.8 17.8 10.0 17.1 14.3 23.8 16.1 18.6 10.3 11.6 12.6 20.0 14.2 12.8 21.3 8.7 23.8 15.6 21.6 22.8 13.7 17.6 45.2 8.8 22.7 14.1 10.1 10.2 12.2 14.0 14.8 8.3 8.4 18.6 13.6 22.9 11.7 13.2 10.0 9.0 38.9 29.9 14.2 10.9 9.8 10.6 3.7 3.4 4.9 9.9 4.5 9.9 3.5 5.6 7.9 4.4 6.0 6.3 7.7 5.1 18.6 6.4 8.9 3.8 2.9 22.8 22.4 31.0 26.8 26.3 23.4 23.4 18.8 20.6 16.1 11.9 14.3 20.4 20.9 21.4 13.1 12.9 15.3 18.7 7.9 10.4 2.0 18.7 13.3 26.6 3.2 26.7 12.9 0.0 32.7 18.8 16.4 18.5 24.3 23.6 20.6 23.8 18.5 31.9 17.0 4.3 18.1 18.9 15.1 64.9 11.8 16.2 30.5 11.8 29.4 12.7 7.5 0.0 22.7 7.5 24.0 19.3 42.9 23.5 13.1 23.1 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50329404-50416461 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 11 "Alveolar cells type 1: 17.9;Ciliated cells: 34.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA059605: AB_2684080, HPA065919: AB_2685578" "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 7.1 2.1 7.5 1.8 5.1 0.9 3.0 2.7 20.2 14.1 5.9 1.6 2.5 8.4 12.1 2.3 2.6 16.4 2.6 2.9 7.1 2.4 18.8 1.1 4.3 3.0 2.0 12.3 10.5 2.0 1.4 1.4 4.9 2.9 4.0 5.7 1.6 2.5 8.4 1.7 3.0 3.0 7.7 3.1 3.7 2.0 1.9 1.4 1.3 5.0 6.1 2.1 7.0 5.6 5.7 1.3 6.0 2.5 3.8 6.7 2.6 6.1 4.9 0.6 2.4 6.5 7.9 0.3 2.1 3.9 2.2 2.6 2.0 5.8 0.4 2.6 4.6 2.2 4.2 0.9 0.6 2.5 6.7 2.4 6.5 2.1 1.7 7.4 5.9 3.5 1.7 3.6 4.6 10.1 1.8 8.5 6.2 2.7 2.6 1.0 0.3 1.9 3.1 0.7 1.6 2.3 0.7 2.8 1.9 6.9 2.3 1.1 1.3 2.5 16.7 0.6 0.1 0.2 5.0 2.7 5.7 2.9 5.7 4.7 0.9 0.4 0.4 1.0 6.2 7.0 6.0 2.5 4.4 6.3 2.3 6.2 4.6 4.4 6.7 1.3 5.7 3.4 3.7 1.4 3.8 0.3 1.2 4.1 2.6 7.5 5.1 2.7 20.2 7.1 2.4 2.0 12.3 2.9 1.4 17.9 6.9 1.3 3.2 2.7 0.4 0.4 0.0 34.8 4.5 10.4 0.0 0.1 5.0 0.9 0.3 2.1 4.7 0.0 1.6 0.1 4.7 1.2 1.1 0.2 0.3 0.0 1.7 6.7 1.9 0.9 8.3 1.1 0.0 0.0 2.3 0.8 1.2 3.7 3.2 5.5 0.7 0.0 1.3 0.0 0.2 2.4 0.2 2.5 3.4 1.4 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75578005-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.7" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 55.4;Ciliated cells: 28.1;Spermatocytes: 46.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Cell line enhanced" "Detected in some" "A-431: 5.7;HEK 293: 3.8;HHSteC: 4.4;RPTEC TERT1: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome NA NA "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.7 2.4 7.1 1.2 11.1 0.7 1.2 7.7 13.2 1.7 2.0 6.2 0.0 1.0 1.7 2.3 2.3 4.1 1.4 1.3 5.1 6.7 11.8 0.7 9.2 1.3 7.1 7.0 3.8 1.6 5.7 8.9 0.7 12.5 2.0 2.4 3.4 1.2 2.0 0.7 0.9 0.9 1.5 7.4 0.9 1.5 27.7 6.1 0.0 6.9 0.0 2.0 1.1 0.9 0.4 0.0 0.2 0.0 0.0 1.6 0.1 5.7 0.7 0.3 0.0 0.3 0.3 0.0 0.3 1.8 2.4 2.0 0.5 1.2 0.1 0.9 0.1 2.3 0.8 0.0 0.5 2.3 0.2 3.8 0.0 0.2 0.0 4.4 0.0 0.1 1.5 2.1 0.4 0.8 1.9 0.1 0.0 0.0 0.4 0.9 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 8.2 0.3 3.1 2.5 0.0 0.0 1.2 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.4 1.6 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 1.2 0.1 7.1 11.1 7.7 13.2 5.1 6.7 7.1 7.0 12.5 6.1 23.8 55.4 0.0 0.4 0.1 16.6 0.8 0.0 28.1 7.9 8.7 3.9 0.0 6.6 2.0 24.5 0.0 0.0 0.0 0.2 0.5 0.2 0.3 1.1 0.0 0.1 9.5 1.7 0.6 0.0 16.4 1.7 0.5 1.7 0.0 0.2 10.4 0.1 0.0 1.1 20.7 19.5 0.0 0.0 46.8 1.7 0.3 0.2 1.0 2.6 0.1 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Group enriched" "Detected in many" 8 "Early spermatids: 261.7;Late spermatids: 219.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA027751 Uncertain Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 2.5 2.7 7.0 2.2 7.1 1.6 2.5 7.0 8.5 2.6 2.4 5.9 5.5 2.3 3.9 5.3 2.6 3.7 2.6 6.6 6.1 6.5 4.5 2.8 2.2 2.5 8.0 4.3 3.0 2.4 3.2 6.5 2.2 8.6 2.8 2.6 3.9 2.0 3.2 7.5 2.7 2.5 4.6 8.4 2.7 2.2 33.4 9.3 1.3 3.9 2.1 3.0 2.8 2.2 1.5 2.7 1.0 1.1 1.4 4.0 1.3 1.0 2.1 3.1 2.2 5.4 4.6 1.3 2.9 2.6 1.3 3.2 1.9 1.5 2.7 1.8 1.8 6.0 0.9 2.6 1.8 2.6 2.9 2.0 1.4 2.3 3.3 3.3 0.6 0.9 2.2 4.7 3.9 1.2 2.2 1.3 6.5 1.5 1.2 3.5 1.1 2.1 8.0 2.1 0.6 1.0 3.4 1.3 0.8 1.7 0.9 4.8 1.4 2.1 0.5 3.5 3.7 1.8 1.6 0.9 2.6 0.6 3.5 1.0 3.3 4.4 5.2 4.0 2.1 2.0 0.0 0.9 1.0 0.9 1.1 4.0 1.5 1.4 2.5 2.7 1.0 3.8 3.8 0.2 1.4 0.4 1.6 2.3 1.3 7.0 7.1 7.0 8.5 6.1 6.5 8.0 4.3 8.6 9.3 0.0 3.0 0.0 5.7 9.6 12.7 1.6 0.0 5.3 3.4 5.2 3.9 2.4 8.3 2.6 261.7 3.6 0.5 0.0 4.4 1.6 6.9 4.0 3.5 1.8 3.1 6.4 2.9 3.1 0.6 219.5 4.6 4.0 10.1 2.8 0.7 10.0 1.5 0.9 8.5 6.1 9.6 0.0 5.6 30.5 13.2 9.7 3.8 3.2 1.1 3.3 CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39175646-39229588 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 3.2;testis: 7.9" "Group enriched" "Detected in some" 14 "Alveolar cells type 1: 3.0;Ciliated cells: 8.1;Club cells: 3.4;Early spermatids: 8.3;Late spermatids: 4.5;Spermatocytes: 6.5;Spermatogonia: 3.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.6;T-reg: 3.2" "Group enriched" "Detected in many" 25 "B-cells: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in some" "HAP1: 1.9;HL-60: 5.0;RT4: 3.4;SH-SY5Y: 6.8" "Low region specificity" "Detected in many" HPA067895 Uncertain NA NA "HPA067895: AB_2685920" "unprognostic (3.57e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "unprognostic (7.46e-3)" "unprognostic (3.26e-2)" "unprognostic (4.26e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-3)" "unprognostic (1.77e-2)" "unprognostic (8.43e-2)" "unprognostic (8.45e-4)" "unprognostic (8.59e-2)" "unprognostic (4.95e-1)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" 0.3 1.1 0.3 0.0 0.6 0.0 0.3 0.1 0.7 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.5 0.9 0.2 0.0 0.4 0.1 0.2 0.3 0.3 0.0 1.6 1.2 0.4 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.3 7.9 0.3 0.1 0.1 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.3 5.0 1.1 0.3 0.0 0.1 0.0 0.2 0.1 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.7 0.1 0.0 0.0 0.0 0.2 3.4 0.6 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 3.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 8.1 3.4 0.0 0.0 0.2 0.0 0.2 8.3 0.0 0.0 0.0 0.2 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.0 0.3 0.0 0.0 6.5 3.8 0.0 0.0 0.0 0.0 0.0 CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell type enhanced" "Detected in many" 7 "Horizontal cells: 76.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 7.7;eosinophil: 2.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 7.7" "Cell line enhanced" "Detected in many" "A549: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002847, CAB011577" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB011577: AB_727019, HPA002847: AB_1080107" "unprognostic (7.01e-2)" "unprognostic (4.86e-2)" "unprognostic (1.41e-1)" "unprognostic (1.25e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" "unprognostic (9.63e-3)" "unprognostic (2.05e-3)" "unprognostic (1.66e-1)" "prognostic favorable (5.54e-4)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "unprognostic (2.67e-3)" "unprognostic (1.99e-1)" 3.3 3.2 8.0 1.8 24.7 3.2 4.3 3.9 28.0 5.4 2.7 7.7 1.8 1.5 4.5 2.8 5.2 2.8 3.1 5.0 8.0 3.7 6.3 2.2 6.9 1.4 3.5 13.2 6.7 4.5 6.2 5.0 5.4 5.9 6.7 2.2 2.0 3.9 4.4 3.0 3.5 1.9 4.0 5.7 2.3 4.9 14.0 5.7 1.6 5.1 0.8 2.1 5.6 4.6 0.7 1.0 7.7 1.0 0.5 0.6 0.2 1.7 12.3 3.5 3.1 3.3 4.5 2.5 2.0 3.8 2.8 3.2 4.0 2.3 1.9 0.4 1.3 5.5 0.5 4.0 3.0 5.9 0.5 2.6 0.0 7.1 3.2 1.6 0.1 0.8 2.6 3.1 6.8 7.1 1.7 1.3 2.2 0.1 2.0 4.2 1.7 0.8 0.8 7.2 1.6 3.0 0.7 3.8 0.1 2.5 9.0 0.7 4.5 4.5 1.1 2.2 7.4 1.7 0.7 7.3 4.3 1.9 7.9 1.5 0.3 0.1 0.3 2.4 0.5 4.2 7.7 1.0 2.1 0.6 0.6 0.3 0.2 0.4 0.3 0.3 0.7 0.6 0.6 4.7 0.5 0.6 1.0 0.2 0.2 8.0 24.7 3.9 28.0 8.0 3.7 3.5 13.2 5.9 5.7 23.8 19.0 0.0 8.3 0.8 16.1 12.0 5.1 6.7 9.1 7.0 31.4 20.0 6.6 5.7 27.2 4.5 0.0 0.0 8.1 2.5 3.1 18.1 1.1 3.0 3.7 76.3 2.4 4.9 5.3 41.5 5.5 1.8 0.0 2.8 1.9 27.7 6.6 0.0 4.9 7.5 19.5 32.3 4.2 2.3 9.8 1.1 39.6 0.8 1.5 24.3 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 80.3" "Cell type enriched" "Detected in many" 4 "Early spermatids: 2056.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 16.1" "Group enriched" "Detected in all" 5 "NK-cells: 5.8;T-cells: 16.1" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 2.4 1.0 1.6 6.5 1.7 12.8 1.5 1.5 2.5 1.0 4.5 0.2 0.2 3.8 0.9 1.1 4.4 0.7 0.9 3.0 1.4 1.9 1.0 1.1 1.1 8.8 1.7 1.9 0.9 0.7 0.0 1.0 2.3 2.8 0.9 5.8 0.9 1.7 0.1 3.9 1.8 4.0 2.2 1.0 2.3 1.8 80.3 0.3 18.3 1.1 6.4 9.5 2.1 1.8 2.0 1.6 1.1 1.4 5.8 16.1 2.9 55.2 21.2 16.3 16.3 2.7 3.3 9.4 13.2 19.5 28.2 31.2 16.0 27.6 27.2 9.7 20.6 29.7 40.7 24.7 16.0 52.7 32.6 11.9 13.8 15.3 26.4 2.0 17.2 9.8 1.2 1.0 17.6 30.7 9.9 17.9 26.4 6.9 34.8 33.8 39.3 23.8 14.0 5.7 54.1 46.0 14.8 14.4 5.9 14.9 12.1 6.7 8.5 24.2 14.3 10.5 12.8 29.6 14.7 6.5 12.5 42.9 19.7 31.2 8.4 9.7 18.7 20.9 24.9 22.8 0.0 1.3 1.1 1.2 1.4 0.6 2.0 5.2 4.3 1.6 0.9 2.7 2.2 0.9 5.8 0.9 1.2 16.1 2.9 1.6 1.7 1.5 2.5 1.4 1.9 1.7 1.9 2.8 0.3 0.0 0.0 0.8 3.1 8.2 1.4 9.3 0.0 0.0 1.2 1.8 2.0 9.8 0.0 2.8 2056.4 2.0 2.9 256.9 2.1 27.0 6.6 2.2 6.9 1.8 31.5 4.8 7.5 4.9 7.5 483.1 19.8 5.7 1.7 3.6 6.2 1.2 2.0 6.2 9.9 1.7 2.3 0.0 2.1 159.2 36.4 5.6 3.4 7.0 12.8 1.4 CDY1 CDY1A ENSG00000172288 "Chromodomain Y-linked 1" Q9Y6F8 Y 25622162-25624902 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY1B ENSG00000172352 "Chromodomain Y-linked 1B" Q9Y6F8 Y 24045229-24048019 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 7.2" "Cell type enhanced" "Detected in single" 40 "Early spermatids: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2A CDY2 ENSG00000182415 "Chromodomain Y-linked 2A" Q9Y6F7 Y 18025787-18028597 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "epididymis: 3.8;testis: 6.0" "Cell type enriched" "Detected in single" 18 "Collecting duct cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "U-266/84: 1.2" HPA066682 Supported NA NA "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDY2B CDY ENSG00000129873 "Chromodomain Y-linked 2B" Q9Y6F7 Y 17877410-17880220 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066682 Supported NA NA "HPA066682: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 355.0" "Group enriched" "Detected in many" 7 "Cholangiocytes: 565.6;Hepatocytes: 2145.0" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "classical monocyte: 32.6;myeloid DC: 32.9" "Group enriched" "Detected in many" 20 "dendritic cells: 32.9;monocytes: 32.6" "Group enriched" "Detected in some" 5 "Hep G2: 96.2;THP-1: 103.6" "Not detected" "Not detected" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 27.1 1.7 0.3 0.5 0.4 2.1 24.7 0.4 0.6 3.1 8.9 0.5 1.5 2.4 7.3 2.1 4.5 6.7 57.7 8.1 0.3 0.0 0.7 355.0 19.8 2.3 0.3 0.6 3.9 1.3 0.0 0.8 1.1 0.6 11.2 1.0 3.8 3.9 4.0 1.6 1.4 3.5 10.2 0.7 4.4 7.0 1.0 0.3 0.4 1.7 2.3 1.5 8.2 16.1 0.2 32.9 0.2 32.6 0.1 1.6 12.1 0.0 0.6 0.0 0.0 14.4 0.0 0.4 0.0 0.0 0.0 0.0 6.7 0.0 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 96.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 103.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 20.8 0.0 0.0 32.6 0.1 1.3 1.8 0.5 0.2 0.2 1.6 32.9 0.2 0.2 0.4 0.2 0.1 0.4 1.7 0.1 12.1 0.3 0.4 0.4 0.6 0.3 0.0 0.3 0.6 0.6 0.3 14.9 74.9 21.0 2.5 14.8 0.0 0.6 565.6 202.1 28.4 15.7 0.0 0.4 0.0 16.2 77.2 1.5 0.0 70.0 17.2 0.8 45.8 1.1 5.8 2145.0 18.9 0.0 36.2 43.0 88.2 134.3 17.3 20.4 37.1 0.0 0.0 8.3 0.9 0.2 93.0 0.5 0.5 0.0 7.2 0.9 1.0 10.2 0.7 20.3 0.0 1.7 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "esophagus: 46.7;intestine: 146.9;liver: 78.6" "Group enriched" "Detected in many" 4 "Enterocytes: 912.6;Hepatocytes: 449.6;Paneth cells: 448.9;Undifferentiated cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA018897 Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 7500000 "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558" "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 5.8 15.3 8.5 8.8 11.7 2.4 5.1 13.0 15.9 9.5 42.3 12.1 11.2 146.9 7.0 11.9 46.7 6.1 14.5 15.2 7.4 6.6 22.5 78.6 6.7 4.6 8.2 10.7 8.4 12.0 10.0 6.8 7.3 10.3 9.7 42.6 13.0 12.7 7.9 11.6 8.9 117.3 10.4 5.6 7.8 10.9 8.5 8.2 9.0 11.7 14.1 12.1 7.6 11.6 6.9 8.9 5.0 10.6 7.9 10.7 5.2 6.9 9.1 9.6 12.8 9.5 8.9 7.3 7.9 12.8 9.3 11.9 9.8 11.5 8.1 7.9 10.3 7.0 18.0 7.0 19.9 7.3 7.2 9.7 7.9 5.2 18.4 13.4 10.4 14.0 12.9 37.7 13.2 22.1 11.5 6.9 5.7 11.1 6.0 15.7 4.4 9.3 8.7 5.2 7.5 9.2 11.0 9.7 9.5 26.4 12.1 6.2 8.2 25.8 6.5 6.7 3.9 11.2 12.9 8.5 12.3 6.5 7.6 5.9 12.0 14.3 9.6 18.9 8.2 9.2 4.7 10.4 4.7 10.1 7.8 9.2 6.1 7.7 10.7 8.9 6.9 9.5 8.6 5.0 7.9 10.6 7.7 6.8 5.2 8.5 11.7 13.0 15.9 7.4 6.6 8.2 10.7 10.3 8.2 29.8 24.0 25.9 13.7 17.3 28.5 25.4 137.6 42.8 12.5 50.6 19.6 13.0 31.5 21.9 1.5 9.8 912.6 0.0 29.5 5.6 12.7 14.5 27.6 449.6 16.6 27.0 23.2 25.2 27.6 1.3 17.3 13.9 10.1 5.4 141.3 17.6 37.9 448.9 17.0 124.1 22.7 32.3 11.3 42.6 10.2 17.9 11.3 18.7 459.3 15.2 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961237-66975148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;liver: 26.7" "Group enriched" "Detected in many" 5 "Enterocytes: 66.2;Hepatocytes: 40.9;Intestinal endocrine cells: 18.9;Mucus-secreting cells: 31.1;Paneth cells: 60.4;Undifferentiated cells: 31.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 8.1;Daudi: 8.9;JURKAT: 14.6;U-937: 7.6" "Not detected" "Not detected" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.5 0.1 0.8 13.3 1.3 0.2 1.0 1.6 1.3 0.6 40.7 0.7 1.4 16.8 0.4 0.7 2.2 1.5 3.0 0.7 1.5 1.0 6.8 26.7 0.9 0.2 0.8 1.1 0.5 7.8 0.0 1.1 0.4 2.2 0.4 17.9 1.1 5.9 0.6 12.9 0.5 41.8 0.5 0.9 0.2 4.6 0.9 0.6 0.5 0.4 2.4 0.5 0.4 0.3 0.7 0.6 2.7 0.6 0.3 0.9 0.2 0.4 3.2 0.4 8.1 0.3 0.2 1.3 0.3 0.2 0.4 0.5 0.5 4.0 8.9 2.7 0.0 0.2 0.7 1.2 0.6 0.1 1.5 6.0 4.4 1.3 2.6 0.1 1.0 0.7 0.3 1.0 0.9 0.2 0.3 0.0 14.6 2.8 1.9 0.3 1.2 1.5 1.6 1.4 2.7 0.5 1.4 0.7 1.4 0.1 0.5 0.4 0.9 0.2 6.1 0.2 0.7 5.4 6.8 0.4 0.4 2.6 0.7 0.2 1.0 3.6 1.3 0.3 7.6 0.2 0.6 0.6 2.7 0.3 0.3 0.5 0.5 0.6 0.4 0.6 0.7 0.9 0.6 2.0 0.3 0.4 0.3 0.9 0.2 0.8 1.3 1.6 1.3 1.5 1.0 0.8 1.1 2.2 0.6 3.0 7.0 0.8 0.0 0.5 0.0 1.0 5.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 66.2 0.0 0.8 0.0 0.0 0.2 1.1 40.9 0.2 0.0 18.9 0.0 3.2 2.6 0.0 1.4 0.0 0.0 31.1 0.2 1.0 60.4 1.1 8.2 0.0 0.0 0.0 0.6 1.3 0.3 0.0 0.0 31.9 0.1 CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 43.4" "Group enriched" "Detected in some" 4 "Cholangiocytes: 2.5;Collecting duct cells: 5.2;Hepatocytes: 5.5" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "U-266/70: 13.3" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" 0.1 0.1 0.7 0.1 0.6 0.0 0.1 0.1 0.8 0.1 0.1 0.1 3.6 0.0 0.1 43.4 0.1 0.0 1.4 0.1 0.8 0.5 0.1 6.6 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 1.2 0.3 0.1 1.2 0.1 0.1 1.8 0.1 0.0 1.7 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.8 0.8 0.5 1.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53055033-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 8 "Cone photoreceptor cells: 473.2;Rod photoreceptor cells: 752.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 42.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042053, HPA049420, HPA066155" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA042053: AB_2677823, HPA049420: AB_2680758, HPA066155: " "unprognostic (3.57e-2)" "unprognostic (3.73e-2)" "unprognostic (3.44e-3)" "unprognostic (2.42e-1)" "unprognostic (4.34e-2)" "unprognostic (4.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "unprognostic (7.75e-3)" "unprognostic (2.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (5.09e-2)" "unprognostic (2.87e-1)" 18.0 12.6 14.5 12.5 17.3 30.3 15.7 49.3 19.6 18.5 13.8 6.6 17.4 8.0 14.2 15.0 14.4 13.5 11.6 12.2 15.9 8.2 16.8 12.3 12.3 9.2 16.0 12.3 18.8 12.9 28.1 39.9 12.3 15.1 13.7 11.5 8.9 17.8 15.3 17.1 14.4 11.1 11.6 20.1 11.6 13.4 7.0 18.7 15.6 17.7 11.2 9.4 13.9 15.1 16.4 42.9 23.7 12.7 12.1 8.8 1.7 5.8 6.8 15.2 12.3 11.3 16.6 2.6 10.7 7.9 5.7 2.5 3.7 5.2 7.8 7.0 8.8 3.9 7.1 7.9 5.6 8.0 2.7 5.9 11.0 6.5 2.4 7.9 15.2 9.2 11.5 5.6 8.3 10.5 7.6 8.4 4.4 12.9 2.6 7.1 2.3 7.6 3.5 5.5 1.7 5.2 26.8 18.2 3.3 3.4 5.5 6.4 7.2 9.5 3.1 7.9 5.7 3.4 7.0 16.2 10.7 5.4 3.9 7.1 8.1 5.6 13.6 7.6 6.6 10.5 23.7 9.2 8.9 5.7 7.6 8.8 12.5 3.9 6.2 5.4 16.4 3.1 4.4 3.0 12.1 12.7 42.9 1.9 1.7 14.5 17.3 49.3 19.6 15.9 8.2 16.0 12.3 15.1 18.7 65.5 56.6 64.3 103.8 50.8 251.0 33.9 43.3 68.3 67.1 85.5 473.2 14.5 39.7 49.7 11.6 77.2 66.9 46.7 32.4 24.2 77.4 86.0 91.5 61.4 61.8 208.2 84.2 88.4 58.8 14.5 100.4 67.6 64.1 74.9 67.1 159.3 29.5 60.4 116.0 47.5 752.2 58.2 73.1 79.9 36.0 65.6 20.8 48.9 69.8 73.2 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625136-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 80.0;seminal vesicle: 66.8" "Cell type enhanced" "Detected in many" 9 "Cholangiocytes: 33.1;Extravillous trophoblasts: 31.3;Spermatogonia: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 11.7" "Lineage enriched" "Detected in many" 6 "T-cells: 11.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" HPA044364 Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 3.0 2.5 2.5 9.0 2.8 14.9 2.1 1.1 2.2 2.5 5.2 1.3 80.0 5.0 1.9 10.2 6.5 1.7 3.6 1.5 2.4 2.4 3.7 2.0 1.8 9.6 3.0 1.2 3.8 4.0 25.5 3.5 3.8 1.5 2.9 6.3 1.6 2.6 66.8 1.2 2.9 5.2 2.3 3.0 3.6 2.8 7.2 1.5 22.4 1.8 4.5 8.8 3.8 3.3 1.9 1.8 1.9 0.7 1.2 11.7 1.0 13.0 10.6 23.9 14.5 4.9 10.5 10.4 18.3 8.8 11.7 12.6 25.9 28.8 34.0 18.8 7.2 15.6 15.7 14.6 9.6 14.5 21.3 6.7 63.1 8.9 13.2 1.5 32.2 12.0 5.4 2.0 14.8 10.5 7.0 13.9 23.2 32.0 30.0 15.4 6.7 47.8 15.8 24.2 21.3 9.6 29.1 22.3 17.9 10.8 17.4 15.1 16.0 15.0 10.4 4.4 16.9 28.0 10.5 9.3 16.9 14.4 8.1 16.8 6.7 12.0 48.5 6.2 24.3 19.8 1.9 0.5 0.3 1.3 0.7 1.2 1.9 3.5 1.6 1.1 1.5 3.3 2.0 0.4 1.2 0.4 1.8 11.7 1.0 2.5 2.8 1.1 2.2 2.4 2.4 3.0 1.2 1.5 1.5 3.0 0.3 6.0 4.4 5.6 1.4 3.7 33.1 2.7 5.7 7.0 0.0 9.6 3.3 3.7 3.3 1.9 3.3 23.3 1.0 31.3 5.6 2.0 0.0 0.8 9.4 0.0 1.7 4.9 0.0 2.2 1.4 2.4 0.0 4.6 5.6 2.7 2.4 3.7 1.1 6.8 1.5 0.0 4.1 23.3 60.3 4.3 6.5 4.4 12.0 1.4 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 23.3;Spermatogonia: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.9 4.8 13.7 17.0 3.9 19.5 8.8 7.4 8.7 9.8 14.4 12.1 10.2 17.7 6.3 5.2 10.6 14.4 20.8 13.6 11.5 12.6 16.0 23.3 9.2 20.2 3.8 14.7 17.1 8.2 6.3 12.6 11.2 6.0 10.8 14.2 14.0 15.5 9.2 21.0 11.8 23.7 19.3 18.5 12.2 25.6 9.4 20.6 6.1 6.2 8.1 4.6 8.3 14.7 8.2 10.6 10.1 13.6 3.7 7.9 9.5 6.9 3.9 9.4 16.5 34.6 7.5 15.5 10.0 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 8.9 4.5 7.5 4.5 5.7 1.0 1.0 0.0 2.7 4.5 1.8 0.0 10.5 0.0 1.7 4.7 2.2 2.0 23.3 1.2 11.7 8.9 2.3 3.5 0.9 8.4 0.0 1.2 3.1 2.1 0.5 5.8 6.6 1.7 2.8 4.7 0.6 1.3 3.5 4.2 3.2 1.2 0.0 2.8 2.5 20.2 1.9 2.9 4.3 7.9 3.4 CHFR "FLJ10796, RNF196" ENSG00000072609 "Checkpoint with forkhead and ring finger domains" Q96EP1 12 132822187-132956304 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 88.4;Rod photoreceptor cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045768, HPA073826" Approved Uncertain "Nuclear bodies,Microtubules" NA NA "Nuclear bodies, Microtubules" "HPA045768: , HPA073826: AB_2732242" "unprognostic (1.46e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (2.08e-1)" "unprognostic (2.14e-3)" "unprognostic (6.56e-4)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.00e-2)" "unprognostic (3.98e-3)" "prognostic unfavorable (4.21e-9)" "unprognostic (5.03e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "unprognostic (1.11e-2)" 13.7 11.4 14.1 19.0 15.0 25.8 12.5 20.0 16.9 12.1 15.2 16.5 13.4 19.0 15.6 16.7 21.6 12.6 14.3 13.7 12.5 9.8 12.8 13.4 17.0 21.7 15.1 12.6 9.6 16.8 9.6 20.6 22.9 13.0 14.3 12.8 15.5 13.9 14.7 21.0 16.7 18.7 17.8 15.1 24.9 16.8 19.2 14.2 22.3 13.5 12.7 18.4 18.6 14.2 6.6 12.1 19.7 17.0 12.3 12.5 10.1 4.4 11.0 9.3 0.8 8.2 10.8 17.3 9.2 7.7 9.8 10.3 8.6 3.8 0.1 8.9 10.7 7.3 7.3 1.1 9.4 5.7 0.6 9.8 14.7 7.5 8.7 17.8 0.6 25.5 14.6 8.5 9.0 6.7 7.1 12.0 1.5 6.2 0.0 6.8 15.0 10.6 11.4 11.1 7.9 8.7 1.4 1.3 4.4 6.5 21.2 9.1 11.6 7.6 7.9 7.1 11.3 14.0 15.1 13.5 0.6 2.2 5.1 3.4 16.1 0.0 2.2 0.0 3.0 8.9 17.6 14.2 19.7 10.8 16.9 10.0 6.6 8.7 11.6 12.1 4.5 8.3 9.1 18.9 12.3 17.0 6.6 12.5 10.1 14.1 15.0 20.0 16.9 12.5 9.8 15.1 12.6 13.0 14.2 11.9 21.6 16.1 4.3 5.5 20.3 8.9 0.0 10.7 19.4 7.0 88.4 10.0 8.3 9.1 51.1 11.3 10.7 0.0 11.9 12.8 7.7 8.7 62.6 7.3 17.2 20.6 20.3 13.5 18.0 58.8 6.9 15.9 10.1 25.2 8.8 8.1 13.4 10.5 8.1 3.4 107.7 19.4 7.3 13.4 19.2 8.4 19.8 21.8 7.3 13.3 CHI3L1 "GP39, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186749 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 336.4" "Cell type enriched" "Detected in many" 7 "Hofbauer cells: 335.7" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 490 "neutrophil: 81.3" "Lineage enriched" "Detected in single" 490 "granulocytes: 81.3" "Cell line enhanced" "Detected in some" "ASC diff: 40.7;ASC TERT1: 90.8;HSkMC: 80.6;THP-1: 128.4;U-138 MG: 38.1;U-87 MG: 37.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 14 "olfactory region: 10.7" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 230000000 "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 19.0 0.8 20.3 53.4 58.0 81.6 23.9 1.2 69.4 4.3 2.1 5.0 0.0 0.9 4.3 25.5 3.5 10.2 1.9 2.6 9.1 17.8 11.9 336.4 10.0 12.4 32.3 3.6 4.5 2.5 0.8 22.9 4.7 66.4 1.5 1.6 9.1 19.3 1.1 10.5 10.0 2.2 3.3 23.5 2.9 1.7 3.4 6.5 0.9 2.0 1.7 14.6 61.5 4.0 0.0 0.0 81.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 40.7 90.8 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 80.6 0.0 0.2 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 128.4 0.0 38.1 0.2 0.0 0.0 0.2 4.8 0.0 37.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.3 0.0 0.1 0.0 0.0 0.1 20.3 58.0 1.2 28.9 9.1 17.8 32.3 3.6 66.4 6.5 6.0 39.7 0.0 19.4 3.8 0.0 0.8 2.5 4.0 15.9 26.2 0.0 1.2 0.0 49.4 0.0 0.4 0.0 0.0 0.0 0.9 2.2 2.2 0.0 28.7 335.7 0.0 0.0 0.0 0.3 0.0 0.9 3.9 13.5 1.8 0.0 40.4 3.1 0.0 0.0 0.1 1.8 0.0 1.7 0.0 0.0 1.0 0.7 0.0 0.0 1.6 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase, acidic" Q9BZP6 1 111290862-111320566 "Enzymes, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 66.6" "Cell type enriched" "Detected in some" 8 "Alveolar cells type 2: 22.2" "Cancer enhanced" "Detected in some" "lung cancer: 1.8;stomach cancer: 2.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "ASC diff: 6.0;HAP1: 3.1" "Low region specificity" "Detected in single" HPA059193 Approved "Intracellular and membrane" NA NA "HPA059193: AB_2683942" "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.7 0.5 0.8 0.3 0.1 0.1 0.1 0.0 0.5 1.0 13.2 0.2 0.1 0.1 0.1 0.1 0.6 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 66.6 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 1.6 0.7 0.0 0.1 0.6 0.6 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.0 0.2 0.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.7 0.2 0.2 0.0 1.6 0.6 0.0 0.0 0.6 0.0 0.7 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 22.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 99.9;lymphoid tissue: 106.5" "Cell type enriched" "Detected in single" 44 "Hofbauer cells: 42.8" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 2.9;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 4 "granulocytes: 2.9;monocytes: 1.1" "Cell line enhanced" "Detected in some" "EFO-21: 2.8;LHCN-M2: 1.7;RH-30: 1.8;U-266/70: 2.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" NA NA 26400000 58000000 "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favorable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 99.9 0.2 0.2 0.4 0.3 26.7 5.5 0.1 0.3 5.9 0.6 0.5 0.1 0.0 2.5 0.2 0.3 0.1 0.2 0.6 0.2 0.1 0.1 0.4 22.1 106.5 0.4 0.1 1.4 1.1 0.0 0.2 0.4 0.5 0.6 0.5 0.3 0.3 0.1 0.1 0.3 0.7 0.2 9.4 4.3 0.1 0.1 0.1 2.3 0.9 0.2 0.5 0.1 0.3 0.5 0.2 2.9 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 1.7 0.2 0.0 0.0 0.1 0.0 0.2 0.0 1.8 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 2.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.9 0.0 1.1 0.2 0.0 1.3 0.2 0.3 0.1 0.3 0.2 0.1 0.4 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 42.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Conserved helix-loop-helix ubiquitous kinase" O15111 10 100188298-100229619 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004240: AB_627784, CAB018564: AB_649197, HPA001402: AB_1079125" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (3.01e-1)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (4.02e-2)" "unprognostic (2.09e-1)" "unprognostic (8.58e-2)" "unprognostic (8.39e-2)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "prognostic favorable (1.27e-4)" "unprognostic (2.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-3)" "unprognostic (2.22e-1)" 16.6 16.6 14.0 14.3 18.9 21.3 14.2 16.0 15.8 11.8 15.0 13.0 13.9 16.1 14.7 12.4 13.5 12.0 11.7 14.5 13.3 17.6 27.2 35.8 14.0 20.8 17.9 6.9 11.4 14.5 19.6 18.2 14.2 16.4 12.9 17.6 9.5 13.9 12.5 23.6 11.0 20.6 16.1 18.6 18.7 15.1 12.5 15.6 22.5 14.5 11.7 15.5 13.8 13.6 3.7 3.4 7.2 4.8 4.0 4.3 1.4 15.8 13.5 13.8 20.6 13.3 12.0 10.6 20.3 20.0 19.0 23.2 15.1 9.4 21.6 12.0 13.8 13.2 15.8 23.0 10.7 21.3 22.9 19.9 14.3 10.7 16.6 11.4 26.4 21.1 9.6 11.5 21.8 21.4 13.2 13.5 17.9 16.2 17.9 20.6 9.6 20.9 16.3 9.0 12.7 9.9 13.7 15.4 9.8 12.0 10.3 8.3 12.3 11.0 8.5 17.6 11.4 17.0 16.2 14.1 11.9 13.4 12.9 23.0 21.1 19.0 21.0 13.0 21.5 9.4 2.6 3.0 5.1 2.4 4.8 4.0 3.7 3.0 4.3 3.4 2.1 3.3 4.2 7.2 4.0 3.2 2.1 2.8 1.4 14.0 18.9 16.0 15.8 13.3 17.6 17.9 6.9 16.4 15.6 11.9 7.8 9.0 4.9 17.5 5.0 6.9 5.1 4.0 4.5 5.2 2.0 5.5 10.0 6.6 6.7 8.3 8.3 0.0 10.3 6.5 5.6 8.2 8.1 13.0 9.4 12.7 5.8 6.2 17.2 6.1 5.8 10.7 6.8 11.8 6.3 4.8 7.9 6.6 5.6 15.3 4.8 19.4 8.1 8.0 13.6 16.7 11.6 7.5 6.0 10.9 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685790-119877291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;brain: 35.0" "Cell type enhanced" "Detected in many" 14 "Cone photoreceptor cells: 82.5;Early spermatids: 63.4;Late spermatids: 28.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA Cytosol "HPA019082: AB_1846803, HPA048812: AB_2680528, HPA075506: AB_2686752" "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 1.4 4.4 14.7 3.3 14.0 15.3 1.6 12.7 35.0 1.6 4.6 2.9 0.0 4.0 1.3 1.5 3.2 0.9 1.6 1.0 9.8 5.7 5.7 1.4 3.0 3.4 3.2 21.9 0.7 0.7 1.2 2.9 2.6 7.4 1.0 5.3 0.6 1.3 1.0 1.3 5.1 3.5 2.6 5.0 5.6 3.5 8.3 9.5 5.9 1.5 0.1 4.9 1.7 1.7 0.4 0.0 0.0 0.1 0.0 1.2 0.8 15.1 13.7 12.0 11.3 1.1 3.3 7.1 11.7 9.7 12.2 9.2 8.7 6.3 11.0 6.3 9.0 6.0 9.5 8.2 6.8 16.9 7.8 6.0 13.9 8.8 5.4 0.1 7.3 12.8 0.7 0.8 14.6 9.0 4.4 9.3 12.2 8.8 9.3 11.5 7.6 13.2 11.1 6.5 5.7 9.3 12.1 21.9 3.6 2.4 6.7 8.6 4.7 19.4 3.8 9.2 6.3 13.7 5.3 7.1 15.3 14.1 10.4 12.7 6.3 7.1 7.5 10.1 8.1 23.6 0.0 0.0 0.0 0.4 0.1 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 14.7 14.0 12.7 35.0 9.8 5.7 3.2 21.9 7.4 9.5 6.0 8.8 0.8 0.6 3.0 7.4 1.6 0.0 1.4 9.1 8.7 82.5 0.9 0.0 0.2 63.4 1.1 0.4 0.0 0.7 4.0 1.1 0.3 1.1 0.8 2.9 0.0 1.7 1.3 1.9 28.5 1.1 1.0 3.3 0.0 1.1 15.4 0.1 0.0 1.1 5.7 15.0 0.0 0.4 11.5 3.5 1.1 0.8 2.5 1.6 1.0 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: AB_2684753" "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.28e-4)" 26.3 55.1 27.8 30.5 43.4 97.6 40.2 40.1 40.7 42.2 23.0 19.9 39.1 12.9 29.1 34.5 26.3 19.1 35.8 26.7 31.0 21.9 21.8 35.3 28.2 30.1 56.0 23.1 48.1 20.9 36.6 41.5 40.0 34.4 34.3 16.5 13.7 25.6 37.1 27.3 32.1 14.9 36.8 55.2 32.4 15.1 12.4 52.6 25.0 30.4 20.2 25.6 51.2 71.8 13.2 9.8 26.2 6.2 6.5 14.4 7.4 8.2 6.2 10.4 3.2 11.9 13.1 8.2 9.0 12.8 9.1 12.2 11.6 5.4 2.8 6.1 5.6 5.3 8.9 13.1 4.1 18.7 12.5 11.6 8.5 15.7 14.3 7.1 8.8 14.4 6.0 18.9 11.4 20.2 10.9 5.3 4.5 10.2 37.3 12.9 5.6 10.4 26.8 6.6 5.2 14.2 10.6 12.4 14.8 6.3 5.4 10.5 8.3 7.8 2.9 13.0 6.5 2.4 6.1 8.1 10.2 7.0 9.8 9.8 22.0 9.1 6.5 6.5 7.2 6.9 26.2 6.2 13.3 13.6 4.4 13.1 13.2 12.8 12.1 4.1 10.1 14.4 11.4 12.7 6.5 4.2 9.8 13.0 7.4 27.8 43.4 40.1 40.7 31.0 21.9 56.0 23.1 34.4 52.6 41.7 97.6 120.6 205.3 149.9 55.8 85.6 28.1 76.3 79.6 26.2 94.2 37.9 16.6 25.9 1.9 110.1 100.8 23.3 23.3 39.1 151.1 171.5 133.9 37.6 51.4 49.3 128.8 78.0 91.9 5.1 86.0 167.5 146.8 47.7 56.3 46.1 27.4 66.6 71.1 11.1 91.9 109.9 142.2 31.2 22.0 132.6 75.5 146.6 44.8 153.2 CLK2 clk2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA055366: AB_2682795, HPA059507: AB_2684044" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.95e-9)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "prognostic favorable (5.43e-4)" 15.3 16.6 14.6 15.0 19.0 12.9 17.1 33.1 20.2 22.3 18.0 18.7 18.1 14.5 22.6 19.9 15.5 18.2 13.9 11.8 17.1 7.3 17.3 18.2 14.7 22.2 16.9 16.9 24.7 15.9 29.2 21.6 19.2 13.5 22.1 13.5 16.1 16.4 18.2 10.4 21.4 15.6 17.0 13.5 27.0 13.7 13.7 20.3 18.1 22.9 8.0 22.2 16.7 20.1 2.8 1.9 4.8 1.7 0.7 4.1 1.1 5.9 5.1 18.7 5.7 9.4 5.1 16.0 5.3 6.5 4.1 4.2 5.4 4.3 13.0 7.4 3.6 2.2 8.6 9.3 6.9 3.9 9.4 7.3 10.3 5.4 6.9 8.1 12.8 10.4 4.1 6.4 6.0 12.2 11.9 7.2 11.1 14.5 9.0 6.2 10.3 8.7 7.6 12.2 15.0 7.3 9.7 11.3 13.9 10.5 13.4 8.9 12.7 2.0 6.4 4.9 14.7 9.8 15.7 4.7 2.5 6.8 4.6 4.4 17.2 14.7 11.8 5.1 9.2 2.9 4.8 1.7 3.4 2.0 0.8 2.9 2.8 3.4 1.8 1.8 2.4 3.4 4.1 2.1 0.7 0.8 1.9 1.7 1.1 14.6 19.0 33.1 20.2 17.1 7.3 16.9 16.9 13.5 20.3 14.9 22.4 4.8 4.8 4.0 5.8 13.3 12.7 4.0 18.2 7.0 3.9 6.8 0.0 5.2 6.3 8.3 4.3 0.0 3.8 7.3 7.2 3.9 9.3 5.8 6.0 4.8 6.4 8.0 10.5 5.4 7.2 5.8 3.3 7.2 7.9 5.4 4.4 3.5 2.8 2.8 5.7 6.5 3.3 8.3 3.8 4.0 10.4 4.4 6.3 4.3 CLK3 clk3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" NA NA Nucleoplasm "Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 20.9 17.2 15.7 24.7 22.5 62.7 31.1 23.4 18.8 24.9 24.6 23.1 16.4 18.6 24.1 17.7 25.3 17.3 21.2 16.4 17.8 13.5 17.2 16.0 19.6 21.9 29.3 14.5 23.7 21.8 19.0 19.9 27.9 16.7 20.6 14.4 19.9 24.8 20.9 28.4 24.1 20.7 19.8 19.2 23.8 19.6 31.5 23.3 28.8 21.0 12.0 23.7 23.2 19.8 38.9 36.0 60.7 46.0 43.6 43.4 39.7 22.3 14.2 18.8 10.5 24.2 18.6 14.9 15.3 24.2 21.9 26.9 19.3 14.8 20.4 11.4 13.6 30.6 15.8 35.0 14.7 14.3 29.0 19.2 25.0 21.1 13.3 38.5 6.7 19.4 23.2 29.4 28.8 24.0 26.8 24.0 20.8 12.2 14.9 12.7 15.8 19.9 22.7 12.0 22.2 10.1 16.1 9.0 13.4 17.1 16.3 10.6 12.5 12.2 13.6 13.5 15.1 12.9 13.5 11.0 13.0 10.0 8.1 20.0 24.5 19.6 16.8 11.4 33.1 16.4 32.9 34.4 45.0 38.5 37.4 37.4 37.7 41.1 39.7 31.9 38.9 42.1 40.1 60.7 43.6 46.0 36.0 43.4 39.7 15.7 22.5 23.4 18.8 17.8 13.5 29.3 14.5 16.7 23.3 6.0 35.5 20.9 38.8 40.0 34.9 14.9 20.4 17.4 18.2 12.2 53.0 22.9 26.6 29.6 59.6 28.3 37.1 23.3 21.0 31.4 22.7 32.5 20.8 10.9 24.3 27.0 28.2 17.2 24.0 14.8 25.6 28.5 27.0 32.5 24.6 17.7 28.8 28.1 19.1 14.2 42.2 12.9 24.4 37.1 17.5 36.6 49.0 39.2 22.6 53.1 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 288.4;Late spermatids: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" No No "Actin filaments" "HPA043746: AB_2678650" "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 12.2 16.4 17.0 17.4 18.4 11.4 17.3 53.8 24.1 17.9 12.2 11.9 18.3 12.4 17.0 16.4 10.5 11.0 13.1 11.4 15.9 9.5 11.8 16.0 10.9 20.3 21.2 12.7 17.4 16.2 15.4 20.2 13.9 16.3 16.7 8.9 10.8 14.4 17.0 20.6 19.5 11.3 11.3 25.8 17.0 11.0 15.7 22.0 15.0 15.8 9.7 12.7 11.4 18.0 13.2 7.8 16.1 6.1 7.7 13.8 5.2 6.7 6.3 5.8 8.4 17.5 14.7 9.7 6.7 7.5 4.0 7.4 6.7 5.5 3.9 5.4 2.8 4.5 9.0 7.5 5.4 6.6 14.1 5.9 1.5 11.8 8.1 6.5 3.1 4.9 6.7 7.8 6.4 8.6 13.2 2.7 2.7 3.5 11.6 5.1 2.8 4.0 11.4 3.0 4.6 3.9 4.0 5.2 5.7 3.9 2.1 6.5 4.4 7.5 4.0 6.9 3.4 4.3 6.6 5.6 8.2 2.9 4.2 7.1 7.6 2.8 3.0 5.9 7.6 4.1 6.5 6.1 12.0 10.0 4.1 13.2 13.2 10.3 8.9 5.9 10.4 13.8 10.6 16.1 7.7 4.4 7.8 9.5 5.2 17.0 18.4 53.8 24.1 15.9 9.5 21.2 12.7 16.3 22.0 14.9 26.7 50.0 37.2 28.3 66.4 19.3 7.6 32.1 23.9 14.0 37.3 16.5 5.0 7.3 288.4 24.8 13.5 23.3 4.1 13.0 20.8 26.1 27.6 11.9 8.8 27.0 5.8 17.2 13.1 350.8 28.4 23.8 15.1 12.6 10.7 34.6 6.5 11.8 27.6 7.7 76.4 19.4 36.0 23.2 17.7 21.5 13.3 34.8 9.1 22.2 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55547138 "Enzymes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 9.3 9.2 7.8 5.8 11.7 1.7 8.4 16.2 14.3 12.5 9.5 5.2 9.2 7.1 10.5 8.4 13.9 8.1 6.7 10.5 7.9 7.9 12.4 9.1 8.2 9.4 7.0 9.8 11.7 8.6 18.7 21.9 8.5 8.4 9.7 8.4 5.6 8.2 9.2 16.1 9.4 12.6 13.8 8.3 9.1 9.6 18.5 5.0 4.0 14.7 5.9 5.2 8.4 17.1 2.5 3.6 0.6 3.0 2.9 4.7 1.4 13.6 5.9 5.4 8.4 8.1 8.2 2.7 14.1 11.6 9.9 9.1 3.7 10.9 3.7 7.3 16.4 7.4 11.4 6.9 10.9 16.7 4.5 2.5 2.9 6.3 4.6 7.2 4.7 3.4 4.8 10.9 13.6 13.4 7.4 9.2 3.1 6.7 7.5 14.8 7.5 2.6 2.7 3.9 11.2 6.9 1.7 6.2 2.4 7.6 7.4 5.3 4.7 10.2 12.6 6.4 4.7 4.2 2.6 12.7 13.4 14.4 4.4 18.9 6.8 4.9 2.3 11.9 4.2 10.6 0.0 3.0 0.6 2.8 3.0 4.7 1.4 3.2 2.5 3.6 2.5 1.9 2.4 0.6 2.9 2.7 2.1 3.1 1.4 7.8 11.7 16.2 14.3 7.9 7.9 7.0 9.8 8.4 5.0 38.7 23.0 9.8 18.1 27.6 61.3 50.4 12.7 12.0 13.6 14.0 41.2 9.5 1.7 11.5 25.0 28.9 20.3 0.0 14.4 5.7 30.8 25.1 3.5 25.9 10.1 31.8 38.2 28.8 12.7 12.1 22.2 14.3 10.1 8.2 19.3 29.6 19.8 15.3 33.9 17.0 39.4 12.9 30.8 56.9 73.3 32.9 4.3 10.2 14.9 46.9 CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1551 "pancreas: 4260.9" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 19853.4" "Cancer enriched" "Detected in many" 188 "pancreatic cancer: 1726.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 2.6;HDLM-2: 1.3;T-47d: 3.4;U-2 OS: 3.0;U-266/84: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA010512 Enhanced "Secreted to digestive system" NA NA 1100000 "HPA010512: AB_1846979" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.12e-3)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.6 4260.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.4 2.7 0.4 1.3 1.1 0.1 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.0 3.0 0.0 1.0 0.0 2.4 1.0 0.0 0.9 0.0 0.5 0.4 1.3 0.1 0.2 0.0 0.3 1.1 0.1 0.4 0.5 0.3 0.0 2.7 1.3 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 23.4 0.0 0.0 0.0 0.0 19853.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 228.2 0.0 0.0 2154.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 15 "granulocytes: 52.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "T-reg: 1.5" "Lineage enriched" "Detected in single" 4 "T-cells: 1.5" "Cell line enhanced" "Detected in some" "HL-60: 1.7;SuSa: 2.5;U-937: 3.1" "Low region specificity" "Detected in single" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 3000000 "Cytoplasmic bodies" Cytosol "CAB000363: AB_2083616, HPA052634: AB_2681892" "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 12.3 0.2 0.2 2.9 0.2 0.0 15.9 0.2 0.2 7.3 6.2 0.2 1.2 0.1 2.9 6.0 8.3 1.0 10.0 10.3 0.2 0.2 2.0 0.8 1.1 1.6 0.2 0.2 0.6 0.9 0.5 0.5 0.7 0.3 6.0 6.9 3.0 5.9 1.3 1.2 13.0 5.3 6.2 0.2 0.5 2.4 2.7 0.2 1.0 0.4 7.9 3.9 4.1 2.0 0.3 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.0 1.5 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 1.7 0.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.9 1.0 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.8 2.5 0.0 0.8 1.4 0.0 0.2 0.3 0.3 0.8 0.9 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 77.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA029954: AB_10670558, HPA029979: AB_10671363, HPA029980: AB_10671094" "unprognostic (1.33e-1)" "unprognostic (2.12e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.00e-1)" "unprognostic (3.72e-1)" "unprognostic (1.68e-2)" "unprognostic (6.43e-3)" "unprognostic (2.95e-2)" "unprognostic (9.17e-2)" "unprognostic (5.24e-3)" "unprognostic (1.50e-3)" "unprognostic (3.00e-3)" "unprognostic (3.27e-2)" "unprognostic (9.72e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" 14.4 17.4 23.1 17.3 17.7 22.4 14.6 25.0 25.0 14.5 18.0 15.5 21.3 15.0 19.5 19.4 12.6 16.9 15.0 18.8 17.6 16.1 13.9 16.6 15.2 19.2 16.0 22.7 22.6 18.4 24.4 20.2 20.6 16.9 16.3 13.1 17.1 17.6 17.9 28.9 16.6 16.5 17.6 12.5 21.7 15.9 63.9 17.8 18.4 15.7 14.1 20.7 16.2 14.8 11.1 9.8 8.1 13.2 9.7 11.5 7.8 7.0 6.7 9.7 15.8 11.0 10.1 11.8 8.4 11.7 21.5 24.1 10.1 4.7 14.7 9.6 12.4 20.2 7.9 12.3 8.7 16.5 10.1 10.9 8.1 7.8 11.2 8.5 11.6 5.5 8.7 6.5 11.8 8.5 11.3 10.0 13.7 17.9 10.8 11.2 11.5 14.7 10.4 4.8 4.7 6.4 11.7 11.5 8.4 6.9 8.6 10.7 8.1 9.5 7.3 12.1 7.3 12.4 9.0 9.2 12.9 9.7 5.1 9.4 12.4 6.4 77.6 5.1 12.2 14.1 8.1 10.2 6.4 10.1 13.2 8.5 11.1 8.9 10.7 9.8 8.1 9.9 8.0 6.6 9.7 9.9 8.2 11.5 7.8 23.1 17.7 25.0 25.0 17.6 16.1 16.0 22.7 16.9 17.8 8.9 8.6 7.3 3.4 3.2 13.3 7.9 7.6 13.4 15.9 7.0 31.4 14.0 0.0 4.0 20.1 9.0 4.2 23.3 7.4 6.2 6.4 3.4 3.5 7.4 6.6 11.1 8.1 9.2 5.9 8.3 7.2 7.5 3.3 13.6 7.5 10.1 6.4 3.5 6.3 3.5 10.9 6.5 4.9 14.4 9.9 4.1 17.4 8.7 5.4 2.8 CNOT4 "CLONE243, NOT4, NOT4H" ENSG00000080802 "CCR4-NOT transcription complex subunit 4" O95628 7 135361795-135510127 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005737 Approved NA NA "HPA005737: AB_1078544" "unprognostic (9.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.47e-2)" "unprognostic (3.61e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.82e-2)" "unprognostic (4.18e-2)" "prognostic favorable (1.61e-4)" "unprognostic (9.08e-2)" "unprognostic (1.00e-2)" "prognostic favorable (7.67e-6)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.33e-2)" 19.4 14.3 19.8 12.0 23.3 11.1 13.8 31.6 24.6 18.7 15.0 21.9 7.0 11.3 21.1 15.2 15.8 16.7 13.8 18.7 19.2 18.0 16.0 16.0 13.6 14.4 18.5 15.1 24.7 14.1 22.6 28.6 16.1 21.1 15.3 13.4 16.4 16.8 15.6 35.0 15.6 12.3 17.1 22.6 13.7 12.3 25.8 18.5 18.5 21.1 12.3 18.1 16.2 15.7 12.0 10.0 21.5 12.7 16.7 15.5 9.1 13.6 12.9 13.3 17.7 22.1 17.6 9.6 15.4 16.8 13.1 16.4 11.1 14.1 13.7 13.4 13.9 18.6 13.0 16.7 11.6 18.8 15.4 12.9 11.3 11.2 9.9 12.3 12.6 13.5 13.5 14.9 16.8 10.5 15.1 13.4 9.8 19.6 10.9 19.2 17.1 17.3 20.5 17.4 12.6 11.0 11.3 13.1 14.8 15.5 12.6 14.1 16.5 17.9 20.2 11.2 12.9 12.4 14.3 18.1 16.0 9.5 14.8 16.6 16.8 15.8 19.5 16.1 14.9 21.2 21.5 11.5 14.9 14.1 11.5 15.5 11.0 12.0 11.7 10.0 12.0 13.1 12.1 10.7 16.7 12.7 8.0 10.1 9.1 19.8 23.3 31.6 24.6 19.2 18.0 18.5 15.1 21.1 18.5 20.8 41.3 39.1 72.1 60.1 49.7 39.2 25.5 29.4 34.2 34.9 100.1 25.2 59.7 27.4 14.2 43.4 27.3 0.0 18.1 19.0 52.1 62.8 60.2 23.3 22.5 52.4 39.0 36.2 21.4 15.3 60.4 32.6 40.5 50.5 23.7 70.1 25.3 25.9 65.0 41.4 66.1 19.4 57.9 120.0 69.4 66.1 37.3 43.1 24.7 86.4 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966741-41977731 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 211.7" "Cell type enhanced" "Detected in many" 4 "Distal tubular cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 49.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Supported "Plasma membrane" NA NA 730000 "Plasma membrane" "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 9.1 8.9 51.4 9.5 72.8 6.7 8.1 13.4 125.3 10.3 7.5 211.7 2.3 7.1 8.0 12.7 15.0 9.3 10.8 7.6 78.4 40.7 14.7 9.6 6.7 10.5 86.7 49.0 11.2 9.2 5.8 4.4 7.8 66.7 11.7 6.4 3.6 15.1 13.2 7.6 11.1 6.4 10.1 160.2 7.1 7.4 4.6 63.5 2.1 7.2 2.2 11.2 9.8 5.7 9.9 49.1 7.3 13.1 7.3 7.5 9.1 13.9 23.9 22.7 27.9 19.4 18.3 9.7 17.5 26.9 45.5 51.4 18.7 12.8 14.9 14.1 22.8 23.4 24.1 15.3 11.6 15.8 14.7 19.3 14.4 16.4 32.4 20.9 14.0 13.1 30.1 8.3 24.9 6.1 16.5 20.7 14.9 10.2 12.1 15.8 8.9 35.9 12.7 5.3 7.6 17.0 22.4 33.3 14.5 12.1 14.3 13.3 18.0 22.2 33.4 38.9 11.6 14.9 21.0 20.8 17.7 19.5 24.1 20.6 13.7 15.6 11.8 17.6 10.9 69.2 4.9 12.1 7.3 7.5 13.1 5.9 9.9 6.5 6.0 11.1 7.0 5.9 6.9 2.6 7.3 10.3 49.1 7.2 9.1 51.4 72.8 13.4 93.8 78.4 40.7 86.7 49.0 66.7 63.5 14.9 10.1 20.1 16.4 14.8 20.3 11.3 20.4 13.4 22.7 33.2 5.9 26.2 106.1 40.0 1.0 17.9 18.3 0.0 37.1 41.6 27.2 18.5 9.2 25.9 34.6 47.7 18.9 18.4 13.2 2.8 35.9 14.9 52.3 31.5 12.9 73.9 30.9 17.3 33.9 48.5 23.1 32.3 36.5 3.9 13.0 16.6 10.9 18.7 18.8 16.6 COL4A3BP "CERT, GPBP, STARD11" ENSG00000113163 "Collagen type IV alpha 3 binding protein" Q9Y5P4 5 75356345-75512138 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 52.0;WM-115: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Uncertain Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: AB_2678075" "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favorable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 30.0 25.5 16.5 17.1 21.9 17.9 21.4 34.4 21.2 26.9 19.9 14.9 21.5 13.5 20.5 11.6 21.9 17.1 17.4 14.9 15.2 16.3 21.1 22.7 19.6 13.4 22.5 12.4 17.9 12.4 24.6 25.9 17.8 18.2 19.0 14.6 14.8 17.5 16.1 33.4 14.2 19.3 18.9 16.6 17.2 17.0 21.3 20.7 17.8 37.4 14.3 15.9 21.8 19.1 6.4 9.8 20.9 16.6 5.1 8.8 5.7 16.6 8.6 8.3 7.2 52.0 14.5 11.1 9.4 11.6 7.2 9.6 12.9 9.6 8.1 20.3 9.9 10.0 10.1 12.6 12.9 11.1 9.9 5.8 6.7 9.5 6.8 13.2 6.6 7.8 10.9 9.2 8.5 9.7 11.8 8.3 10.7 12.1 12.2 9.5 8.8 7.9 5.0 10.7 3.8 6.4 6.7 11.0 7.4 11.8 20.2 6.4 6.4 11.8 8.3 11.6 18.3 8.1 11.4 11.3 4.9 5.9 8.8 7.7 11.3 14.9 9.4 8.5 11.4 45.0 5.0 13.9 10.6 6.0 15.6 5.6 6.0 6.2 5.6 9.8 6.4 5.9 5.8 20.9 5.1 16.6 5.7 8.8 5.7 16.5 21.9 34.4 21.2 15.2 16.3 22.5 12.4 18.2 20.7 56.6 58.5 6.4 28.0 16.7 30.7 32.7 22.9 71.0 75.1 17.4 21.6 13.6 18.3 19.6 83.3 28.1 19.2 0.0 19.2 13.9 20.9 36.3 47.5 17.9 31.6 41.3 26.4 55.9 33.0 73.0 32.2 37.4 49.0 19.8 15.6 31.1 21.5 13.1 39.3 22.3 33.1 19.4 19.6 41.5 31.5 23.3 23.2 21.3 14.3 38.3 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941607-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.3" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 779.9;Syncytiotrophoblasts: 542.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 118.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 560000 Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 18.6 49.0 29.4 14.3 28.8 24.3 27.8 19.6 32.9 22.4 23.4 42.4 36.1 21.0 19.8 33.8 58.1 19.4 36.8 28.1 28.9 22.3 31.1 139.3 30.9 17.0 29.0 18.4 36.3 27.2 14.1 12.7 59.0 23.3 25.7 8.9 24.9 67.3 30.9 21.5 27.7 28.6 15.5 41.0 17.8 24.8 18.2 23.7 11.5 19.2 44.0 32.0 36.3 28.0 11.2 55.1 10.9 60.0 12.9 15.6 28.0 19.1 19.7 2.3 19.5 22.2 19.8 0.8 21.8 27.4 18.7 21.4 16.7 22.4 7.7 9.7 31.1 7.4 26.3 3.7 23.3 5.0 16.7 24.9 13.8 10.5 39.0 41.5 23.0 5.5 25.2 28.9 16.2 16.1 18.0 17.5 12.5 55.7 16.5 15.0 118.8 9.0 41.3 4.8 52.7 6.7 13.6 19.5 10.6 19.7 60.8 9.5 8.4 7.2 61.7 18.0 1.3 13.3 64.7 20.9 33.4 12.8 10.9 16.3 6.1 2.6 6.3 36.0 31.0 23.0 10.2 60.0 10.9 15.6 39.9 12.8 11.2 10.8 12.6 47.7 10.7 9.6 10.6 2.4 12.9 26.6 55.1 13.3 28.0 29.4 28.8 19.6 32.9 28.9 22.3 29.0 18.4 23.3 23.7 116.1 64.8 45.5 189.7 90.7 68.3 29.9 109.5 88.3 85.3 144.8 9.8 779.9 271.9 173.4 3.6 68.7 98.5 0.0 167.1 75.3 99.4 123.4 70.4 231.9 281.1 23.8 81.1 74.9 149.0 7.4 124.3 142.1 227.7 154.1 89.3 151.7 163.3 110.1 169.0 60.7 34.5 135.8 91.5 4.4 5.3 107.9 542.4 36.6 110.1 180.5 COP1 "FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1, E3 ubiquitin ligase" Q8NHY2 1 175944831-176207493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cytotrophoblasts: 24.8;Extravillous trophoblasts: 29.0;Syncytiotrophoblasts: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 22.4 15.8 14.8 20.1 16.7 19.1 19.3 24.6 19.7 21.4 23.9 15.3 17.7 16.1 23.5 16.5 22.3 14.9 15.5 14.5 12.8 11.6 17.2 22.9 17.8 24.1 13.1 11.3 14.4 20.8 15.6 24.5 17.2 15.7 15.4 26.1 18.1 20.2 21.4 19.2 25.4 22.1 19.7 10.9 27.1 17.5 23.4 15.0 39.3 18.3 15.8 25.0 22.6 17.6 1.5 2.0 13.7 3.4 0.5 2.7 1.0 14.2 7.7 12.5 6.7 12.5 12.9 23.5 11.0 13.5 11.8 11.2 12.9 15.0 29.1 10.9 12.5 8.7 13.4 11.5 16.8 10.6 9.0 7.0 12.3 9.4 12.8 13.2 22.2 14.3 11.3 14.0 11.6 14.8 11.3 16.7 12.4 18.0 11.5 14.0 17.7 13.1 11.7 21.3 25.9 0.8 11.3 10.8 16.9 16.3 43.9 10.0 17.6 12.9 20.6 14.0 21.8 14.6 29.7 16.1 10.0 7.0 13.4 9.4 14.7 25.2 26.4 8.4 13.2 11.5 6.1 2.7 10.1 1.8 3.4 1.4 1.4 2.1 1.4 2.0 1.5 2.7 2.0 13.7 0.5 3.1 1.1 1.5 1.0 14.8 16.7 24.6 19.7 12.8 11.6 13.1 11.3 15.7 15.0 20.8 16.4 0.0 0.0 0.0 0.0 0.0 0.0 8.1 5.7 8.7 0.0 24.8 18.3 12.3 0.0 0.0 0.0 0.0 19.7 29.0 0.0 0.0 7.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.0 0.0 0.0 17.6 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3231 "pancreas: 3541.6" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 8426.3" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AN3-CA: 16.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" NA NA 17000000 "CAB025197: , HPA021836: AB_1846005, HPA052215: AB_2681764" "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 1.0 3541.6 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.3 0.0 0.3 0.0 1.9 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 3.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 5.0 13.2 1.2 0.0 0.0 0.0 8426.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.9 0.0 0.0 77.5 0.0 2.3 847.8 0.0 0.7 0.0 0.0 0.0 0.0 0.5 2.4 0.0 1.4 0.0 0.0 0.0 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266827-130289798 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 529 "pancreas: 1357.9" "Cell type enriched" "Detected in some" 6 "Exocrine glandular cells: 4303.0" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.5;CACO-2: 7.5;RH-30: 6.2;SCLC-21H: 3.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 1357.9 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 0.1 2.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 4.5 0.0 0.1 0.0 0.0 0.0 0.7 0.0 7.5 0.0 0.0 1.0 0.0 0.6 0.0 1.4 0.0 0.1 1.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.4 0.0 6.2 0.1 0.1 0.7 3.4 0.0 0.2 0.0 2.1 0.3 0.0 0.2 0.0 0.0 1.1 0.8 0.6 0.0 0.7 0.2 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.7 6.6 3.8 0.0 0.8 0.0 4303.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.0 24.4 0.0 2.8 764.8 8.6 0.0 0.0 0.3 0.0 0.0 0.3 1.5 0.1 0.2 0.0 0.2 0.1 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865256-148897196 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 111.7" "Cell type enriched" "Detected in some" 15 "granulocytes: 4120.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1118 "basophil: 111.7" "Lineage enriched" "Detected in single" 1118 "granulocytes: 111.7" "Cell line enriched" "Detected in some" 43 "HEL: 81.5" "Low region specificity" "Detected in single" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 12.4 0.6 0.4 12.0 0.4 5.6 6.2 0.4 0.5 25.4 14.1 0.8 4.4 7.1 14.1 21.2 16.5 3.7 50.9 4.5 0.4 0.2 5.8 2.8 37.3 15.2 0.4 0.4 2.0 7.2 0.7 0.8 1.3 0.5 37.3 16.4 8.5 8.8 5.8 1.4 12.7 20.2 24.3 0.4 1.0 13.7 7.1 0.4 3.6 1.4 9.9 7.1 14.0 8.9 0.0 0.0 111.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 81.5 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 111.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.5 0.4 29.8 269.3 0.0 0.2 1.4 0.0 0.2 0.0 16.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.6 0.1 4120.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.3 CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "blood: 25.2;testis: 30.4" "Group enriched" "Detected in some" 20 "Early spermatids: 46.3;Late spermatids: 106.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 8.0;naive CD8 T-cell: 20.3;T-reg: 25.2" "Lineage enriched" "Detected in single" 114 "T-cells: 25.2" "Cell line enhanced" "Detected in some" "RH-30: 11.2;RT4: 5.1;U-266/84: 8.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" NA NA Nucleoplasm "HPA020322: AB_10960562" "unprognostic (2.44e-1)" "unprognostic (3.76e-1)" "unprognostic (1.50e-1)" "unprognostic (5.94e-2)" "unprognostic (4.96e-2)" "unprognostic (7.10e-3)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (3.26e-1)" "unprognostic (5.02e-2)" "unprognostic (5.83e-4)" "unprognostic (1.43e-1)" "unprognostic (8.88e-13)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 1.6 0.1 0.1 0.1 0.4 0.0 1.0 0.5 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.4 0.1 0.1 1.6 0.0 30.4 0.1 0.1 0.1 0.1 0.7 0.8 0.1 0.0 0.0 0.2 0.0 0.0 25.2 3.1 0.8 0.0 0.1 0.6 0.0 0.0 0.0 0.4 3.3 0.2 0.4 2.4 0.0 0.0 0.0 0.0 1.1 0.1 0.4 0.7 0.0 0.0 1.9 0.7 0.7 1.2 0.5 0.0 0.0 0.0 1.1 0.0 1.2 1.4 0.0 0.9 0.0 1.6 0.1 0.0 0.4 0.0 0.8 0.0 0.0 0.0 11.2 0.4 1.5 5.1 1.4 0.2 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 8.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 8.0 4.1 0.0 0.0 2.1 20.3 0.0 0.0 0.0 0.0 25.2 3.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 2.8 0.0 0.0 46.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 106.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.6 1.9 0.0 3.9 0.0 0.0 0.0 CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746385 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.2;prostate: 10.6;retina: 13.0" "Cell type enhanced" "Detected in some" 11 "Basal glandular cells: 26.9;Early spermatids: 15.2;Muller glia cells: 22.3;Pancreatic endocrine cells: 12.5;Urothelial cells: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.0;CACO-2: 6.2;EFO-21: 3.5;Hep G2: 9.5;OE19: 4.2" "Region enriched" "Detected in single" 10 "olfactory region: 15.5" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "unprognostic (2.85e-2)" "unprognostic (1.95e-1)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.88e-1)" "unprognostic (9.35e-2)" "unprognostic (1.65e-1)" "unprognostic (5.23e-2)" "unprognostic (6.99e-2)" "unprognostic (3.57e-4)" "unprognostic (9.61e-5)" "unprognostic (1.75e-1)" "unprognostic (9.09e-2)" "unprognostic (1.41e-2)" 0.2 0.1 0.1 9.8 0.1 0.2 0.2 0.1 0.1 9.4 16.2 0.7 0.8 0.2 8.3 1.7 3.7 0.2 0.3 0.1 0.2 0.1 0.3 0.1 0.7 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.3 0.3 10.6 7.2 13.0 0.1 0.7 0.1 0.2 1.3 3.4 0.7 0.3 0.5 1.3 0.0 0.0 0.2 1.5 0.6 4.1 5.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 3.5 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.8 0.0 4.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 26.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.3 0.0 0.0 5.6 0.0 0.0 0.1 1.6 2.4 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.7 22.3 12.5 2.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 26.0 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880726 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: AB_2682948" "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favorable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 18.5 10.9 17.2 22.8 17.5 37.0 17.4 42.6 18.8 20.1 17.2 16.8 17.1 9.9 25.1 15.2 14.1 18.9 21.3 14.5 17.1 8.7 11.1 12.3 16.9 14.4 20.5 12.0 31.6 23.4 24.3 13.0 13.3 15.8 18.4 11.6 14.6 14.9 16.7 28.2 20.4 16.4 17.0 13.6 17.4 14.7 29.1 20.2 29.6 19.5 13.8 16.1 19.0 29.9 4.7 2.3 10.6 3.8 2.0 2.7 1.1 5.6 14.5 18.8 8.3 11.5 11.4 9.8 8.1 13.7 14.0 13.7 13.1 10.6 15.6 9.7 15.5 9.0 10.9 21.6 6.7 16.0 26.3 8.7 12.2 13.4 8.3 12.8 12.2 17.6 10.1 6.8 15.6 18.9 8.7 10.5 8.0 13.9 21.4 7.6 19.3 8.1 5.9 15.4 5.4 6.0 38.3 14.9 11.9 5.4 7.6 15.7 10.3 13.9 13.7 8.2 12.7 12.2 12.0 16.3 17.2 17.2 8.8 7.4 10.0 10.8 30.3 3.5 7.3 12.1 2.9 1.7 1.3 2.7 2.2 1.4 4.7 1.3 2.0 1.0 3.3 1.4 1.7 10.6 2.0 3.8 2.3 1.3 1.1 17.2 17.5 42.6 18.8 17.1 8.7 20.5 12.0 15.8 20.2 41.7 45.9 13.8 25.5 49.9 31.9 37.0 43.3 32.1 33.0 10.4 23.6 14.6 5.0 17.4 38.0 35.3 24.0 0.0 17.7 9.4 24.3 32.2 30.0 25.1 17.8 27.0 14.5 32.5 38.7 57.1 52.3 33.5 16.9 27.9 22.4 31.4 22.7 17.3 48.1 10.7 15.8 45.3 36.0 33.1 46.0 51.4 25.7 35.9 23.8 31.6 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492197-149551552 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Suprabasal keratinocytes: 741.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Approved Cytosol NA NA Cytosol "CAB016680: AB_1614518, HPA051334: AB_2681446" "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favorable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 33.5 35.8 26.0 26.9 35.2 71.0 40.2 32.0 39.3 33.8 38.2 28.2 40.5 23.2 41.0 29.4 66.1 31.8 36.0 45.7 24.4 26.1 24.0 30.1 37.5 27.3 28.0 29.8 31.7 23.9 46.9 30.9 28.7 38.0 38.1 31.4 25.5 38.5 39.3 51.4 48.4 31.8 45.8 33.9 23.6 34.2 28.6 24.1 38.6 32.0 53.1 41.1 45.0 40.0 28.6 40.6 47.4 39.6 34.2 41.9 40.8 36.9 24.7 41.6 39.4 43.0 52.7 44.5 52.8 50.2 41.2 43.4 48.1 50.1 19.7 58.5 56.1 44.2 37.8 29.3 71.1 63.0 28.5 17.7 26.7 28.6 22.1 38.7 41.8 43.0 43.1 73.8 46.2 74.5 45.6 47.4 35.6 22.5 29.7 46.4 23.2 38.3 16.9 21.8 40.9 60.2 28.7 33.0 22.4 28.7 64.4 32.1 28.9 39.2 52.6 64.3 38.5 49.3 36.4 47.0 48.5 25.5 32.1 50.3 27.6 35.4 30.4 45.3 30.4 58.6 47.4 36.6 35.4 29.0 38.7 33.1 28.6 36.7 32.9 40.6 23.4 39.9 34.0 31.1 34.2 39.6 24.2 41.9 40.8 26.0 35.2 32.0 39.3 24.4 26.1 28.0 29.8 38.0 24.1 137.0 158.5 75.9 513.8 608.0 132.0 46.4 73.9 278.4 290.0 109.9 60.9 146.8 77.9 135.8 55.7 139.6 98.3 23.3 160.7 185.9 198.0 381.5 112.3 94.7 120.9 143.0 124.9 225.9 143.6 66.9 96.4 139.7 145.1 118.2 136.8 145.0 155.3 98.2 105.0 78.9 100.0 155.2 201.9 125.6 93.5 741.0 293.5 102.2 111.1 404.2 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 10.5;testis: 9.0" "Group enriched" "Detected in some" 8 "Early spermatids: 23.1;Late spermatids: 19.5;Spermatocytes: 11.4" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 40 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 42 "granulocytes: 10.5" "Not detected" "Not detected" HPA051334 Uncertain Cytosol NA NA Cytosol "HPA051334: AB_2681446" "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.2 10.5 0.2 0.1 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 10.5 0.1 0.2 0.1 0.2 0.2 0.0 0.0 0.0 1.5 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.5 0.0 0.0 0.0 0.1 0.4 0.9 0.0 0.0 0.1 0.0 0.0 1.8 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.4 1.1 2.4 0.2 0.0 0.0 1.0 CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273731 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 287.2;Late spermatids: 600.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015410 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" Nucleoplasm "CAB015410: AB_831049" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.38e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.38e-6)" "unprognostic (8.05e-2)" "unprognostic (1.09e-1)" "unprognostic (5.00e-2)" "prognostic favorable (9.62e-5)" "unprognostic (2.23e-3)" "prognostic unfavorable (8.34e-4)" "unprognostic (3.54e-1)" "unprognostic (2.52e-1)" "unprognostic (5.52e-3)" "unprognostic (4.74e-2)" 30.1 36.3 30.8 25.9 30.8 21.0 26.3 36.3 42.8 30.9 33.0 27.7 32.9 32.6 37.9 29.8 31.3 38.0 34.9 28.5 26.2 26.9 32.0 33.5 30.1 25.8 27.2 27.8 31.4 42.8 34.2 35.9 32.8 30.3 35.3 19.3 28.4 38.0 37.7 52.3 26.7 42.3 34.1 21.4 36.4 32.5 48.3 24.6 29.2 33.0 31.8 33.7 31.4 26.1 6.4 11.4 29.6 12.1 8.7 7.6 7.1 21.6 25.8 14.7 20.3 19.4 20.8 29.6 31.9 20.1 22.9 21.5 21.2 18.7 19.8 25.3 22.7 24.3 21.0 13.8 32.3 18.5 16.8 33.4 24.6 20.5 22.6 56.4 20.2 18.9 31.4 23.0 15.5 23.2 28.6 33.3 14.7 27.7 10.5 21.6 25.3 26.0 21.2 15.8 25.7 40.7 22.4 18.2 17.6 24.1 34.0 18.2 32.9 38.1 31.8 35.7 21.4 22.8 26.6 35.1 32.9 29.6 28.6 24.2 23.1 11.1 21.2 26.4 17.3 23.8 4.7 11.0 14.6 7.6 12.1 7.4 6.4 5.9 7.3 11.4 5.6 5.0 5.3 29.6 8.7 11.1 5.5 5.2 7.1 30.8 30.8 36.3 42.8 26.2 26.9 27.2 27.8 30.3 24.6 44.7 51.2 45.8 92.5 50.4 45.6 14.1 25.5 64.3 62.6 40.1 25.5 56.2 28.2 62.7 287.2 39.4 93.0 0.0 60.1 78.4 37.7 85.7 57.8 25.6 57.5 90.6 44.4 40.5 51.6 600.1 27.9 56.2 27.0 73.1 56.1 34.9 72.9 48.0 37.8 40.4 47.4 38.8 58.6 35.2 26.6 42.2 105.8 64.7 38.3 96.3 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Urothelial cells: 208.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 28.5 22.9 30.7 18.3 32.5 21.4 28.6 40.1 42.6 26.4 21.5 32.3 15.7 19.0 37.3 27.3 23.4 28.0 22.1 28.8 31.7 22.3 17.3 11.8 28.4 17.3 28.6 30.1 38.1 25.4 56.2 29.2 33.1 28.7 26.2 17.4 30.5 23.9 23.1 26.3 35.3 17.1 24.0 23.2 20.9 21.8 13.0 33.9 13.3 21.4 14.2 17.4 25.5 28.8 3.7 15.7 4.8 1.8 5.9 4.0 1.2 23.6 11.5 31.3 30.0 15.7 24.1 23.6 30.9 39.5 28.1 27.3 14.8 18.5 17.8 13.5 29.1 18.9 20.2 23.7 42.7 20.4 28.4 51.7 5.7 38.1 11.3 32.3 12.4 15.2 23.0 36.2 42.8 58.0 36.9 29.8 15.6 12.6 36.8 27.1 15.8 17.3 15.3 22.9 17.2 16.7 32.4 22.4 27.9 25.8 19.9 46.4 18.2 26.3 27.3 30.8 19.4 13.9 18.1 33.9 25.5 27.8 14.7 24.6 16.5 23.6 25.1 37.8 14.0 42.6 3.8 1.8 3.4 3.4 0.8 4.0 2.5 3.8 3.4 1.8 3.7 2.1 3.1 4.8 5.9 0.6 15.7 1.7 1.2 30.7 32.5 40.1 38.8 31.7 22.3 28.6 30.1 28.7 33.9 35.7 17.1 22.2 117.4 69.8 122.3 44.0 38.2 16.0 23.9 22.7 56.9 29.6 6.6 26.6 42.8 62.1 10.7 0.0 35.7 33.5 53.2 138.6 3.5 18.6 19.2 68.3 60.3 44.8 14.9 42.7 79.1 18.5 57.3 11.8 40.8 105.4 42.3 29.6 62.2 4.1 58.4 71.1 106.1 6.0 9.6 91.6 104.9 13.4 31.9 208.0 CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165517-64356259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 12 "Early spermatids: 121.0;Late spermatids: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol NA NA Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" 7.2 7.8 10.2 11.9 15.1 11.6 8.7 12.2 10.6 8.7 7.4 7.6 11.6 7.0 11.1 9.9 15.7 10.8 7.8 5.6 8.9 7.6 8.6 6.0 8.4 9.6 6.6 4.7 8.5 8.8 10.4 16.1 7.2 7.2 6.8 7.9 10.1 8.2 14.5 6.5 10.4 6.8 11.1 5.3 8.2 6.8 41.3 7.3 11.8 11.5 5.6 11.2 8.3 10.6 4.1 4.1 8.8 5.1 5.3 8.0 2.4 5.1 10.9 7.9 10.2 6.8 9.3 7.2 6.4 6.6 10.9 9.8 8.7 10.1 8.1 3.5 10.1 11.4 11.9 20.6 12.9 12.8 15.4 5.3 7.6 8.7 5.8 7.8 14.0 9.0 8.2 17.2 11.1 15.9 9.5 11.9 8.4 9.2 8.5 9.8 7.1 7.1 4.4 7.4 6.8 5.7 12.0 9.9 6.5 8.8 20.8 12.8 7.8 8.4 5.1 7.4 13.6 8.9 5.5 12.8 9.9 11.9 7.9 7.9 9.8 18.9 6.9 9.2 10.3 6.1 0.9 3.6 5.6 5.7 5.1 8.0 3.6 5.1 4.1 2.7 4.1 5.1 4.7 8.8 5.3 4.3 4.1 3.9 2.4 10.2 15.1 12.2 10.6 8.9 7.6 6.6 4.7 7.2 7.3 26.8 9.9 7.1 8.7 10.3 44.6 6.5 5.1 16.0 13.6 5.2 64.8 5.8 1.7 8.2 121.0 8.4 8.4 0.0 6.1 7.4 8.9 7.9 3.5 4.0 9.4 9.5 21.9 9.2 9.7 209.9 5.8 10.3 6.8 10.0 10.0 6.9 9.1 7.0 9.6 8.7 29.5 6.5 8.5 27.2 18.4 13.7 3.4 7.7 10.3 10.1 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941149-1981338 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 218.1;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles NA NA Vesicles "HPA034868: AB_10671235, HPA056572: AB_2683178" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 18.7 22.2 24.8 34.9 19.5 38.1 16.7 30.8 28.9 14.1 19.0 18.2 18.9 27.0 16.5 19.0 22.1 16.9 20.4 16.0 23.3 18.3 19.3 17.9 21.8 35.1 17.3 21.2 18.6 27.0 11.4 24.4 16.7 18.7 18.7 8.7 19.7 26.6 16.0 29.0 23.3 22.1 15.1 12.7 39.1 24.1 58.5 17.4 20.6 16.5 18.1 32.2 17.1 17.1 4.0 5.9 11.2 14.1 3.5 4.9 2.3 23.3 12.6 17.5 27.5 6.2 11.6 14.7 14.5 9.6 11.1 13.6 10.3 12.8 14.7 12.2 9.2 6.1 16.9 9.4 17.7 4.9 13.3 20.4 10.4 20.5 17.4 9.9 16.5 26.4 11.5 11.7 11.5 7.4 8.5 13.1 18.4 21.7 50.6 7.3 13.6 32.8 21.8 31.8 6.5 14.2 28.6 11.1 23.8 8.3 24.6 28.3 23.2 11.0 18.1 16.0 6.9 11.5 27.3 15.6 14.0 11.0 29.3 16.8 32.7 17.3 18.0 14.2 15.7 14.6 2.8 4.0 5.0 4.9 6.2 3.5 3.9 3.6 4.2 3.9 4.0 2.9 4.1 11.2 3.5 14.1 5.9 2.5 2.3 24.8 19.5 30.8 28.9 23.3 18.3 17.3 21.2 18.7 17.4 14.9 17.0 12.0 15.7 19.5 44.1 10.1 7.6 13.4 14.8 10.4 39.3 9.9 8.3 15.1 218.1 19.9 22.5 0.0 25.3 17.2 15.8 22.1 29.9 14.0 12.9 23.8 29.2 14.1 17.0 503.0 19.0 20.5 13.5 5.4 20.2 21.3 24.4 16.5 17.7 12.6 37.2 12.9 14.4 15.6 13.1 22.1 15.2 27.3 18.0 28.5 CSNK1G3 ENSG00000151292 "Casein kinase 1 gamma 3" Q9Y6M4 5 123512099-123617045 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027010 Approved NA NA "HPA027010: AB_10602803" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "prognostic favorable (9.90e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.92e-3)" "unprognostic (4.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.52e-1)" "unprognostic (1.97e-3)" "unprognostic (4.38e-1)" 20.7 15.0 15.5 21.7 22.7 11.1 37.7 23.7 31.7 18.8 24.0 8.6 11.2 23.5 19.4 18.4 18.8 14.6 17.7 14.0 22.2 18.0 16.2 27.7 29.0 21.8 13.3 17.7 18.7 15.8 18.6 18.1 16.2 16.6 13.2 27.4 9.1 15.3 14.1 15.6 13.4 24.9 18.6 16.1 16.5 18.2 16.4 11.4 17.2 16.2 16.5 17.4 21.9 18.2 13.6 5.3 11.3 5.9 12.7 9.5 5.1 13.1 12.6 19.0 18.0 19.4 21.8 9.4 14.3 17.1 15.8 23.7 11.3 21.1 0.0 18.6 17.1 18.4 9.6 15.2 28.2 27.4 19.8 10.4 9.3 14.7 12.0 17.3 4.8 9.6 18.4 18.4 17.8 33.8 18.9 17.2 6.5 5.2 10.7 13.3 9.1 6.5 6.0 10.7 10.4 8.7 7.3 20.1 12.5 11.8 14.5 16.5 12.0 15.8 10.5 23.1 16.5 13.8 13.7 15.7 23.4 17.6 14.1 15.7 12.0 13.2 11.8 14.0 14.0 15.0 11.3 5.8 2.5 7.1 5.6 9.5 13.6 5.9 6.2 5.3 12.9 6.1 6.4 4.6 12.7 5.9 4.7 7.3 5.1 15.5 22.7 23.7 31.7 22.2 18.0 13.3 17.7 16.6 11.4 20.8 13.1 23.3 20.5 18.3 27.5 18.7 5.1 18.7 12.5 10.4 7.9 7.5 18.3 20.1 6.7 24.5 25.7 0.0 21.9 13.3 21.6 23.4 5.7 20.9 8.5 85.8 31.4 31.9 15.4 9.7 18.4 16.5 15.1 24.4 23.7 25.7 24.4 40.3 18.4 17.0 2.8 0.0 15.5 22.0 52.1 16.4 5.6 27.4 22.3 37.6 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 21.5 26.7 23.2 20.6 31.3 16.7 24.1 26.3 32.8 22.2 26.1 28.2 19.5 21.9 24.3 15.7 31.9 23.3 17.7 29.2 21.8 21.9 24.5 23.1 18.6 21.9 21.3 22.6 24.9 27.5 27.7 24.6 23.1 29.4 20.7 24.2 19.6 23.8 22.4 58.8 27.0 22.5 23.3 21.3 21.8 26.5 51.6 23.2 30.3 22.4 22.4 25.7 26.2 22.8 19.8 25.4 23.3 27.3 18.7 19.4 15.7 44.4 39.7 36.7 22.6 14.0 24.5 23.8 26.1 26.4 30.3 33.8 40.0 29.2 39.7 16.8 21.5 42.6 34.5 40.3 39.1 43.2 13.9 14.6 53.8 10.6 38.7 24.1 46.7 11.9 22.4 41.4 27.9 77.7 29.7 32.7 34.5 52.8 26.2 27.7 14.7 56.1 16.6 52.5 39.9 27.4 33.4 32.1 32.4 26.1 28.2 38.4 30.6 22.3 43.0 39.7 29.7 28.7 18.3 30.7 32.2 27.6 20.8 38.6 27.2 64.0 39.2 16.1 28.1 32.5 23.3 19.7 22.2 16.1 27.3 19.4 19.8 15.7 15.5 25.4 18.9 16.0 15.0 12.1 18.7 25.2 21.1 16.4 15.7 23.2 31.3 26.3 32.8 21.8 21.9 21.3 22.6 29.4 23.2 59.6 72.9 45.0 31.0 36.5 45.7 53.7 33.1 80.3 85.3 41.8 29.5 35.3 34.9 61.1 104.2 34.8 33.8 0.0 43.6 47.2 34.8 36.9 60.3 26.4 28.9 57.2 33.8 22.1 30.2 104.8 38.0 35.3 13.5 67.7 41.3 34.4 54.4 24.6 34.6 56.2 26.8 51.8 32.5 61.3 54.1 43.8 51.4 32.4 39.1 45.0 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58197920 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 194.0;Late spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.40e-5)" "prognostic unfavorable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 22.8 14.5 15.2 15.2 14.2 14.8 33.5 11.1 17.0 20.4 22.2 12.6 15.1 11.7 19.0 21.4 20.2 15.8 18.7 19.7 12.8 11.5 16.2 21.1 20.0 28.7 10.8 13.9 23.9 28.1 34.3 14.4 29.1 11.6 22.0 15.0 12.9 15.6 15.2 25.4 50.5 18.0 18.8 11.2 26.6 21.1 69.1 10.2 44.3 25.9 12.0 18.5 28.9 33.8 8.9 8.0 8.7 14.1 12.8 14.5 11.7 18.5 20.9 16.2 19.3 22.9 32.4 28.6 14.4 22.2 28.7 18.2 39.1 15.9 33.9 20.3 20.2 14.3 21.9 29.1 26.0 36.5 11.2 15.9 18.6 14.0 34.9 35.2 30.0 19.1 31.7 39.0 21.7 38.8 29.2 30.0 30.8 37.4 9.9 17.4 12.9 29.6 24.9 26.0 9.5 24.3 40.4 33.1 17.9 21.3 20.7 13.7 15.6 34.5 16.2 27.5 25.5 10.1 25.2 24.6 19.7 23.4 15.4 19.2 22.7 18.6 48.2 17.5 20.8 18.3 8.7 14.1 7.4 11.9 12.4 13.5 8.9 14.2 11.6 8.0 7.8 14.3 14.5 0.7 12.8 10.8 7.6 10.7 11.7 15.2 14.2 11.1 17.0 12.8 11.5 10.8 13.9 11.6 10.2 11.9 16.1 14.2 9.3 26.3 21.2 19.7 10.2 13.4 3.4 8.7 3.9 13.4 6.6 13.1 194.0 21.7 13.4 23.3 14.7 21.3 13.6 13.7 8.1 16.3 14.8 17.5 16.1 16.0 26.2 237.3 13.3 17.6 11.8 6.4 12.3 21.7 19.9 13.1 18.4 11.5 21.4 12.9 15.5 43.2 38.8 25.3 20.5 15.2 15.1 20.1 CSNK2B "Ckb1, Ckb2" ENSG00000204435 "Casein kinase 2 beta" P67870 6 31665236-31670343 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004349, HPA005944, CAB013087, CAB016059" Approved NA NA "CAB004349: AB_626791, CAB013087: AB_2533571, CAB016059: AB_626792, HPA005944: AB_1847290" "unprognostic (1.61e-1)" "unprognostic (3.21e-2)" "unprognostic (8.88e-2)" "unprognostic (1.55e-3)" "unprognostic (9.51e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-3)" "unprognostic (1.60e-1)" "unprognostic (7.52e-2)" "unprognostic (1.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (5.88e-2)" "unprognostic (1.72e-1)" "unprognostic (9.67e-2)" "unprognostic (3.72e-2)" 28.1 30.5 26.6 28.8 28.0 30.3 27.6 26.9 42.9 29.9 32.7 30.8 24.0 13.9 26.2 101.7 51.5 30.1 32.0 43.8 24.4 23.1 41.1 49.8 34.4 33.8 25.4 24.6 32.9 42.1 3.5 26.4 39.6 23.6 34.3 26.0 30.4 30.3 32.5 40.8 58.3 31.6 32.2 26.6 33.3 26.9 66.0 20.8 60.2 38.5 41.8 33.4 28.3 25.9 20.6 24.9 21.3 22.8 16.3 20.2 16.0 0.0 6.6 0.0 10.9 6.6 11.1 8.1 15.3 26.4 31.2 29.5 0.0 9.6 23.5 8.2 11.2 7.6 0.0 0.0 26.9 30.6 11.4 27.4 0.0 0.0 0.0 16.9 25.7 0.0 21.4 0.0 0.0 0.0 0.0 0.1 13.0 0.0 0.0 0.0 0.0 14.6 0.0 7.8 17.6 0.0 11.9 0.0 15.0 14.9 8.8 0.0 18.6 0.1 0.0 11.6 7.1 0.1 0.0 7.5 13.1 15.8 14.8 0.0 9.7 15.1 14.9 9.3 0.0 11.8 16.5 22.8 21.3 16.2 22.3 16.0 20.6 16.7 16.7 21.1 16.4 14.4 12.7 18.4 16.3 14.1 24.9 20.2 16.0 26.6 28.0 26.9 42.9 24.4 23.1 25.4 24.6 23.6 20.8 47.6 61.3 116.2 104.5 165.3 59.1 72.4 79.0 78.9 69.4 96.0 11.8 179.7 228.8 159.2 342.7 124.4 178.9 23.3 152.4 207.2 146.1 108.2 129.0 116.0 254.7 46.1 120.6 101.3 177.4 185.4 142.4 189.2 145.1 172.3 148.8 98.5 153.7 196.4 117.8 289.9 31.0 135.8 118.5 386.2 176.3 162.9 235.8 124.6 164.7 113.8 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679801-79756623 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 89.2;Late spermatids: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 6.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 10.6 8.2 6.2 12.8 9.5 21.8 9.5 7.5 12.2 7.9 12.0 14.4 5.3 13.4 11.9 9.3 11.4 9.8 10.0 6.6 6.8 5.7 8.9 13.4 10.2 14.4 12.3 5.1 7.7 13.4 4.6 7.9 10.6 9.1 9.1 6.2 8.4 10.6 8.3 12.1 20.9 13.8 8.2 6.8 15.3 12.2 27.2 10.6 26.2 9.4 8.8 14.8 11.4 8.9 0.7 1.5 6.4 1.0 2.4 2.0 0.5 8.1 9.1 5.1 7.2 4.1 3.4 16.9 5.5 4.0 5.0 5.0 6.0 5.2 10.4 2.6 3.6 6.1 10.0 4.3 5.7 2.1 9.6 7.8 5.4 4.5 8.1 5.9 23.7 13.3 5.7 5.5 5.4 2.5 3.1 6.0 7.9 6.5 5.3 1.9 7.3 15.8 18.7 7.9 2.7 12.2 12.3 6.7 12.5 3.7 8.5 7.9 8.1 6.5 6.5 8.7 4.0 5.2 13.9 8.2 8.7 12.6 3.4 5.9 4.5 16.6 10.3 7.4 12.0 6.1 0.0 1.0 6.4 1.3 0.9 1.1 0.7 1.0 2.0 1.5 0.4 1.3 0.7 2.7 2.4 0.9 0.2 0.3 0.5 6.2 9.5 7.5 12.2 6.8 5.7 12.3 5.1 9.1 10.6 0.0 2.6 3.7 4.2 7.6 9.8 3.1 5.1 6.7 3.4 3.5 13.7 7.8 1.7 4.4 89.2 5.2 11.7 23.3 6.2 6.5 4.2 8.1 6.9 5.5 7.7 22.3 5.8 7.4 7.3 97.9 7.2 9.5 6.8 0.0 15.1 7.8 8.0 14.4 9.9 5.7 14.3 0.0 5.1 5.9 6.8 8.8 15.9 13.3 10.6 11.5 CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm NA NA Nucleoplasm "HPA062654: AB_2684819" "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" 32.9 22.5 15.9 21.9 13.9 19.9 41.1 12.2 16.4 34.8 30.7 27.6 31.8 24.2 34.5 30.7 31.3 30.9 43.4 25.9 15.5 8.6 34.1 47.5 30.2 33.2 15.0 13.1 44.9 50.8 28.8 12.6 71.3 15.9 41.5 19.8 35.4 34.3 31.5 23.2 30.5 41.3 33.7 12.4 39.1 34.2 15.1 16.1 33.2 41.0 27.2 29.9 32.5 28.4 3.4 6.6 29.3 12.4 6.7 11.0 7.5 10.3 13.3 7.8 25.8 21.4 20.0 29.6 13.9 20.0 13.4 11.7 17.3 25.8 6.2 12.1 24.5 9.2 21.1 11.6 16.7 6.9 22.2 9.1 23.8 16.3 23.1 25.7 14.6 33.4 22.7 20.4 10.2 11.5 21.3 19.7 9.8 19.3 22.4 14.2 28.9 12.8 42.7 5.5 16.5 13.7 17.7 11.1 13.5 17.1 12.7 5.2 13.1 12.1 26.4 13.1 10.4 14.5 35.2 17.2 21.4 13.1 16.3 6.0 14.4 9.3 14.7 19.1 13.9 11.8 20.3 12.4 29.3 11.0 10.2 7.1 3.4 6.7 7.0 6.6 3.2 4.3 5.7 24.5 6.7 10.4 2.3 5.6 7.5 15.9 13.9 12.2 16.4 15.5 8.6 15.0 13.1 15.9 16.1 41.7 40.2 27.7 26.3 24.3 14.0 27.9 45.9 9.4 20.5 29.6 2.0 35.7 28.2 31.7 1.5 43.6 72.4 46.7 37.2 35.9 36.1 31.8 17.4 49.9 35.0 6.4 20.8 58.3 79.9 2.0 55.0 36.2 32.1 26.2 44.5 46.7 32.1 35.1 41.4 42.5 24.7 25.8 34.0 1.6 4.7 17.8 45.4 46.7 37.6 26.7 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846739 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 169.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria NA NA Nucleoplasm Mitochondria "HPA052607: AB_2681883" "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 44.5 43.6 28.2 31.6 34.8 17.6 39.6 57.1 33.4 49.0 48.4 36.7 47.7 24.4 50.4 32.9 38.0 41.9 37.7 34.6 31.2 16.5 32.8 32.6 51.3 31.3 37.1 19.9 52.5 53.9 33.7 25.4 42.9 31.0 40.5 38.6 29.3 45.8 60.9 48.8 39.9 36.1 44.1 25.7 38.1 43.1 21.0 40.9 62.9 40.1 32.8 33.9 46.1 63.0 7.3 9.3 18.7 9.7 8.2 11.5 7.1 11.0 4.8 23.1 14.7 20.8 35.9 7.7 12.0 22.8 11.9 10.7 6.1 18.1 13.6 13.8 25.5 4.6 8.9 9.6 11.7 12.5 4.5 4.1 18.8 7.4 4.9 19.4 8.5 11.0 34.3 12.4 10.8 9.2 25.6 18.6 8.3 9.8 24.1 5.9 5.1 9.1 5.1 11.7 7.0 6.1 12.2 169.3 17.8 9.3 16.1 4.3 9.6 16.7 9.6 14.4 14.7 17.4 14.9 14.9 10.6 11.6 11.9 4.2 7.2 7.7 16.4 11.9 7.9 8.2 11.5 9.7 14.7 6.9 9.0 8.2 7.3 9.9 8.0 9.3 6.5 11.5 8.7 18.7 8.2 7.7 7.7 6.4 7.1 28.2 34.8 57.1 33.4 31.2 16.5 37.1 19.9 31.0 40.9 68.5 36.0 33.5 41.6 60.0 18.7 31.1 79.0 13.4 23.9 45.4 15.7 36.7 13.3 64.0 44.2 58.1 55.7 0.0 117.0 34.7 57.1 49.1 24.3 49.7 36.0 19.1 46.8 80.4 63.9 111.0 48.1 36.8 40.5 66.7 42.3 41.1 88.4 51.8 45.6 23.9 10.8 71.1 55.2 5.8 25.8 66.6 47.0 40.6 35.4 58.0 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861960-37984469 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Peritubular cells: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles NA NA 10000 Vesicles Nucleoplasm "HPA048325: AB_2680359" "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favorable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 12.8 6.3 11.1 7.8 12.4 5.6 22.0 30.2 14.1 15.5 19.9 8.0 25.7 9.3 14.5 18.3 16.8 12.2 37.2 18.9 13.1 5.9 26.7 13.3 19.0 4.9 7.8 9.9 13.7 10.2 8.3 9.4 20.6 6.9 17.5 20.3 15.6 45.5 22.4 12.5 34.8 11.2 21.3 8.1 11.3 19.7 8.1 8.3 2.9 10.0 13.9 6.9 19.6 21.7 0.0 0.2 1.1 0.5 0.0 0.5 5.6 15.8 6.9 2.9 9.0 11.3 16.2 21.4 10.9 13.8 7.6 8.9 10.0 13.0 0.0 6.7 13.5 3.1 13.3 7.0 20.7 6.1 0.0 5.5 9.7 7.4 22.6 10.3 0.0 2.4 8.3 50.9 8.0 9.6 8.6 10.6 4.4 3.1 0.0 12.5 5.0 3.9 0.0 11.8 6.5 1.0 4.4 5.5 0.1 24.3 10.6 2.4 7.5 6.0 10.8 12.2 12.1 10.4 2.6 8.4 5.5 7.7 10.2 6.8 0.2 0.0 0.0 6.1 5.4 10.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 1.1 0.0 0.0 0.0 0.0 5.6 11.1 12.4 30.2 14.1 13.1 5.9 7.8 9.9 6.9 8.3 62.5 19.3 0.0 13.3 26.8 9.6 33.8 71.4 14.7 31.8 22.7 0.0 27.6 19.9 10.8 21.9 17.5 10.3 0.0 4.2 7.7 21.7 12.0 1.1 13.9 6.3 9.5 43.5 19.0 9.5 32.3 66.4 5.5 8.5 0.0 17.7 7.1 10.0 5.8 92.3 14.9 1.6 25.8 22.7 2.8 15.8 25.1 7.9 2.2 29.9 14.2 CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated protein homolog" Q6UX04 5 64768930-65018763 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation, Dwarfism, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Early spermatids: 197.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "HPA020344: AB_1856644, HPA024149: AB_1856645, HPA065809: AB_2685561" "unprognostic (1.71e-1)" "unprognostic (6.47e-3)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (8.91e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (5.27e-6)" "unprognostic (1.58e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" "unprognostic (2.05e-1)" "unprognostic (2.74e-1)" "unprognostic (7.45e-3)" 15.6 16.4 22.0 14.9 30.4 21.7 16.4 30.1 25.6 16.5 17.5 13.8 14.0 11.8 19.4 15.7 17.3 14.9 13.8 22.1 20.6 19.9 17.5 12.1 12.8 17.0 22.3 20.7 23.3 10.9 21.4 28.8 17.5 26.2 18.6 18.7 11.4 13.3 16.0 24.0 13.8 15.9 24.7 23.3 15.0 13.9 19.6 23.6 22.5 17.2 18.2 18.6 18.6 20.0 15.1 14.6 8.6 11.5 17.0 15.9 9.0 15.2 10.2 18.4 34.0 15.8 19.3 20.5 16.1 13.4 18.0 19.0 17.0 19.4 22.7 28.2 16.7 20.3 9.7 19.2 29.1 32.9 18.9 15.7 17.0 17.2 14.1 24.2 17.8 11.6 12.8 22.4 22.7 28.9 16.0 19.0 26.0 16.5 15.0 17.8 15.2 24.7 16.1 14.9 8.0 12.4 23.0 24.7 23.6 17.1 13.3 21.9 9.7 19.6 8.0 18.1 18.3 17.4 26.2 15.8 10.6 18.7 16.9 25.6 11.7 15.2 22.3 19.9 31.3 18.8 8.6 11.5 7.9 12.8 11.3 15.5 15.1 14.2 15.9 14.6 11.9 15.4 15.9 2.5 17.0 8.5 12.0 15.1 9.0 22.0 30.4 30.1 25.6 20.6 19.9 22.3 20.7 26.2 23.6 8.9 25.8 20.1 22.0 14.5 30.0 55.8 20.4 33.5 14.8 14.0 13.7 36.6 18.3 35.9 197.3 26.9 10.5 23.3 28.8 45.9 24.6 20.8 18.5 10.5 28.6 19.1 28.7 14.1 17.2 37.1 35.6 23.8 13.5 29.7 16.0 31.3 33.5 10.5 33.9 21.9 53.9 32.3 28.4 43.0 28.9 17.6 25.7 23.6 26.6 17.4 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: AB_2681013" "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 9.3 16.2 13.9 22.9 26.4 51.1 9.1 14.2 20.9 9.2 10.3 18.8 12.8 10.2 16.1 8.1 15.3 8.5 13.3 12.7 15.7 17.0 9.4 13.2 15.6 30.7 16.3 14.3 11.5 12.2 20.3 27.8 9.8 20.0 11.0 12.7 13.3 12.6 10.9 31.7 12.4 14.2 12.5 16.3 23.4 12.4 22.6 13.7 16.9 16.2 8.0 29.3 14.1 12.6 9.2 10.2 31.4 9.8 13.6 19.1 10.2 9.3 2.9 3.4 3.8 5.4 7.8 3.1 13.8 20.2 14.4 8.5 2.4 4.4 10.7 5.0 13.5 15.7 3.6 4.0 8.4 21.5 47.2 6.1 5.3 5.2 2.0 10.7 5.3 25.3 8.5 6.8 17.4 18.2 13.7 5.8 7.6 2.2 9.4 20.1 1.4 5.2 7.7 3.6 2.9 4.9 4.7 6.9 10.3 4.7 3.2 4.4 3.3 11.7 4.0 3.4 5.4 4.0 6.7 6.5 24.7 5.6 8.6 5.6 24.8 23.5 12.0 18.1 6.0 5.2 31.4 8.6 20.8 10.7 9.8 12.9 9.2 15.8 14.4 10.2 6.2 14.7 11.4 19.4 13.6 9.5 6.2 19.1 10.2 13.9 26.4 14.2 20.9 15.7 17.0 16.3 14.3 20.0 13.7 41.7 25.6 39.6 48.8 106.7 75.4 32.7 25.5 12.0 19.4 17.4 88.4 5.4 5.0 18.3 32.8 37.9 13.4 46.7 16.5 3.8 37.2 52.3 78.5 22.1 19.0 63.5 29.9 21.5 32.3 24.7 23.6 47.1 70.9 34.3 10.3 22.6 15.2 18.7 19.8 10.3 49.3 6.5 34.4 52.6 13.8 135.9 3.4 73.4 12.0 56.3 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708633 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 94.7" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 2: 65.3;Ito cells: 79.2;Kupffer cells: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.3;eosinophil: 6.9;intermediate monocyte: 11.9;myeloid DC: 4.0;non-classical monocyte: 11.7;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 55 "dendritic cells: 5.3;granulocytes: 6.9;monocytes: 11.9" "Cell line enhanced" "Detected in many" "HMC-1: 38.8;HUVEC TERT2: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome NA NA Centrosome "CAB037302: AB_1078622, HPA040472: AB_2677001, HPA048436: AB_2680390" "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 14.6 4.9 10.4 8.8 25.5 3.8 4.1 2.9 17.6 8.1 16.6 6.5 8.1 7.8 8.7 16.1 4.5 12.2 21.6 4.1 12.4 8.1 14.7 21.3 28.6 8.5 4.6 10.4 32.7 21.2 4.8 16.6 94.7 6.6 5.1 7.5 5.9 9.3 7.3 1.5 3.7 11.0 8.1 4.8 16.4 15.0 6.3 7.3 34.5 7.2 1.5 5.2 13.2 10.5 0.1 5.3 6.9 11.9 0.1 0.1 2.1 0.0 18.3 8.8 6.2 0.2 0.1 14.0 1.2 1.7 7.2 8.2 2.6 0.1 0.1 1.8 0.3 0.1 17.1 5.4 0.4 3.1 0.1 4.4 8.8 2.5 8.9 7.9 0.0 38.8 0.5 2.9 1.3 0.5 11.3 22.0 2.5 6.6 3.7 6.0 0.5 2.6 0.0 10.0 16.9 0.0 0.7 7.8 0.0 20.1 18.3 4.0 4.5 0.0 1.8 7.7 13.5 0.0 5.8 0.1 0.0 0.1 0.0 0.0 14.6 3.0 0.0 0.1 2.4 1.2 1.3 5.3 6.9 0.0 11.9 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 1.6 0.1 11.7 5.3 0.0 2.1 10.4 25.5 2.9 17.6 12.4 8.1 4.6 10.4 6.6 7.3 47.6 65.3 5.9 0.6 3.2 19.8 1.9 40.8 16.0 40.9 21.0 2.0 5.6 1.7 27.2 1.2 13.0 2.1 0.0 20.1 14.4 11.4 3.9 23.1 16.3 21.3 17.5 0.0 79.2 64.1 2.2 13.8 42.1 11.8 30.7 7.7 14.5 31.5 1.7 12.7 5.9 2.9 0.0 2.3 3.9 4.1 2.8 11.9 0.7 2.8 9.3 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;skeletal muscle: 46.1" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 80.4;Enterocytes: 44.6;Late spermatids: 59.2" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 19.1;eosinophil: 51.8;neutrophil: 16.4" "Lineage enriched" "Detected in many" 23 "granulocytes: 51.8" "Cell line enhanced" "Detected in many" "ASC diff: 10.1;HaCaT: 8.4;HMC-1: 17.2;MCF7: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Golgi apparatus, Vesicles" "HPA071581: AB_2686421" "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 8.2 1.6 2.6 6.8 5.0 10.3 5.2 1.4 3.9 3.6 16.6 12.0 8.3 14.2 1.7 1.5 2.1 1.2 1.7 17.6 3.6 2.0 2.2 1.4 14.0 2.5 6.8 3.0 0.7 1.7 1.1 1.1 0.3 4.7 3.1 4.7 1.9 4.8 4.8 46.1 4.6 25.8 1.2 3.4 4.7 6.9 2.0 6.5 1.1 22.3 8.7 3.3 2.1 9.6 0.3 2.2 51.8 0.0 0.7 0.6 0.3 2.8 2.0 5.7 1.4 10.1 0.4 0.1 1.9 6.1 1.0 1.1 0.9 1.4 0.2 0.6 6.1 3.4 8.4 3.5 0.1 0.6 0.2 0.1 1.1 3.9 0.1 0.1 0.1 17.2 1.1 7.3 0.4 0.2 6.6 0.6 0.1 0.4 0.1 0.7 8.7 0.0 0.3 0.6 2.8 2.0 2.6 0.0 0.3 0.0 2.8 0.4 0.3 0.4 1.1 0.0 1.4 4.8 0.4 0.4 0.8 1.0 1.3 1.6 0.6 0.2 0.0 0.0 2.7 0.2 19.1 0.0 51.8 0.6 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.0 0.4 16.4 0.7 0.0 2.2 0.0 0.3 2.6 5.0 1.4 3.9 3.6 2.0 6.8 3.0 4.7 6.5 80.4 21.1 2.7 6.6 10.3 0.0 34.6 2.5 2.7 19.4 0.0 0.0 0.1 1.7 7.8 19.1 2.8 44.6 0.0 30.2 0.1 3.1 14.5 15.0 0.8 0.4 4.8 8.1 8.6 1.2 59.2 2.8 1.4 0.0 0.0 13.0 1.6 13.0 28.8 5.3 0.3 0.1 12.9 2.1 0.9 3.4 3.6 0.1 14.9 16.9 10.7 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028569, HPA064809" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA028569: AB_10794319, HPA064809: AB_2685357" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 18.8 10.2 12.6 16.6 16.4 10.0 17.2 14.5 29.5 22.5 30.1 13.6 11.5 18.5 33.1 11.5 20.2 18.5 21.9 49.2 12.4 11.0 10.9 11.0 24.5 11.6 11.9 16.8 18.8 21.7 11.1 14.6 26.0 19.7 21.3 6.9 18.2 15.3 25.8 45.2 17.8 17.0 38.8 10.6 14.7 23.3 15.7 12.7 11.8 11.4 11.6 12.9 26.7 17.8 15.0 14.7 23.9 15.6 17.3 19.5 11.0 25.7 20.5 12.8 16.1 9.6 10.9 19.8 35.6 28.7 29.1 19.2 37.7 7.8 14.3 17.5 31.2 20.5 20.6 12.5 20.2 10.6 20.9 20.8 5.7 25.1 21.6 30.6 13.8 21.7 24.7 25.3 26.4 15.2 17.5 24.1 9.8 18.1 24.9 17.7 16.8 13.7 10.4 19.9 10.5 16.5 17.2 18.9 13.3 17.5 20.3 20.3 14.1 24.0 28.9 20.4 15.7 20.8 10.9 45.1 37.5 17.0 33.5 44.4 27.8 22.8 16.5 29.8 14.5 19.9 22.1 14.2 23.9 19.5 15.6 14.0 13.5 14.8 17.9 12.6 15.0 11.3 10.8 23.9 17.3 10.6 14.7 17.6 11.0 12.6 16.4 14.5 29.5 12.4 11.0 11.9 16.8 19.7 12.7 23.8 10.9 16.6 82.6 89.4 12.3 27.3 17.8 5.3 7.9 10.4 2.0 40.8 14.9 91.0 24.5 19.4 61.2 0.0 75.9 65.4 32.8 38.1 20.7 6.0 20.1 11.1 26.2 20.3 16.7 17.7 21.0 12.0 35.4 33.3 33.0 11.1 89.1 42.1 21.2 11.5 10.2 32.3 50.1 15.2 15.6 62.7 77.9 17.5 20.3 41.6 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131306 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.5" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 84.2" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.7;ASC TERT1: 15.8;fHDF/TERT166: 12.9;GAMG: 19.8;HAP1: 10.0;HSkMC: 14.6;NTERA-2: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA 11000 Nucleoplasm Cytosol "CAB012405: , HPA015040: AB_2669141, HPA015655: AB_2669265" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 13.9 3.3 14.3 4.2 25.0 1.1 8.6 8.6 76.5 12.2 3.5 8.6 0.5 2.0 6.4 5.8 5.8 3.3 7.1 5.8 21.9 21.9 1.9 1.2 3.0 4.3 11.9 22.5 6.4 2.1 1.5 7.4 1.1 13.9 4.7 4.4 0.5 2.5 4.7 1.9 4.7 2.7 17.0 10.4 4.6 2.5 2.2 8.5 0.0 2.1 1.4 2.9 5.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 16.7 15.8 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 12.9 19.8 0.0 10.0 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.6 0.0 0.0 14.6 7.3 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 1.1 0.0 0.5 0.0 4.1 2.5 0.0 0.0 1.2 6.1 0.0 0.0 0.0 0.0 3.4 4.3 0.7 0.1 0.0 0.0 1.4 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 25.0 8.6 45.8 21.9 21.9 11.9 22.5 13.9 8.5 8.9 1.1 0.0 1.0 13.5 2.2 5.1 0.0 4.0 4.5 3.5 3.9 0.0 0.0 0.0 1.3 2.9 0.0 0.0 0.0 0.0 9.3 0.5 0.0 0.0 0.1 9.5 0.0 0.6 0.3 0.9 19.2 0.0 13.5 0.0 0.0 84.2 0.3 0.0 3.9 0.2 2.1 6.5 16.8 1.6 0.7 8.4 0.0 0.0 0.0 1.3 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078274-150257457 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 60.5" "Cell type enhanced" "Detected in many" 10 "Bipolar cells: 18.2;Cone photoreceptor cells: 15.7;Horizontal cells: 33.4;Muller glia cells: 39.2" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 2.5;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 18.6;BJ: 8.4;BJ hTERT+: 19.4;fHDF/TERT166: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced Approved NA NA "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.25e-4)" "prognostic favorable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 2.9 3.9 23.3 2.1 23.5 1.6 2.0 9.3 60.5 3.1 2.8 16.5 0.8 2.8 4.3 3.5 3.0 2.8 4.0 14.4 23.5 17.5 2.9 1.8 2.7 1.6 14.9 14.5 4.3 3.5 1.4 4.7 2.9 20.2 3.9 3.5 2.1 2.0 3.6 2.3 2.1 2.7 6.4 23.4 2.1 2.2 4.2 15.9 0.0 4.1 0.0 1.5 3.3 2.0 2.5 1.5 0.0 0.5 0.0 0.0 0.0 0.8 3.2 18.6 2.9 0.0 0.9 0.3 8.4 19.4 2.8 0.6 0.1 0.0 0.0 0.3 8.5 2.8 0.0 2.7 0.0 3.5 3.8 1.6 0.0 4.9 0.0 4.0 0.5 0.5 0.5 0.0 1.7 0.2 1.7 0.9 0.5 0.0 0.0 1.9 0.1 0.3 0.0 0.4 0.2 1.0 0.0 2.1 0.7 0.0 0.8 7.1 6.8 3.5 2.6 0.8 1.6 0.0 0.0 1.6 2.6 1.0 1.7 0.9 0.8 0.0 0.0 2.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 23.3 23.5 9.3 19.3 23.5 17.5 14.9 14.5 20.2 15.9 0.0 0.0 0.0 0.1 0.5 18.2 9.1 2.5 0.0 1.2 3.5 15.7 0.0 0.0 0.3 0.0 5.6 0.0 0.0 0.6 0.0 2.2 0.9 4.6 0.0 1.3 33.4 2.9 8.6 0.0 0.0 1.7 1.0 5.0 0.0 0.2 39.2 0.2 0.0 3.5 0.3 8.9 12.9 4.1 0.1 0.2 0.5 0.2 0.0 1.3 0.1 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.6" "Cell type enhanced" "Detected in many" 8 "Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cell line enhanced" "Detected in many" "OE19: 36.9;SH-SY5Y: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006308, HPA071064" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 140000 "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532, HPA071064: " "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favorable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favorable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 4.3 14.3 43.9 5.8 44.9 0.7 6.6 14.4 37.2 7.7 22.1 20.7 4.3 21.1 6.0 33.8 4.9 18.4 12.2 6.4 29.5 24.1 61.6 39.9 11.8 1.1 24.9 37.0 3.4 13.8 13.0 7.2 3.1 13.8 13.1 21.4 4.1 8.5 6.2 13.8 2.8 19.9 7.4 8.1 4.1 15.6 9.3 11.0 0.0 14.1 1.0 1.2 6.0 3.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 18.3 2.3 6.5 1.2 10.9 9.2 0.8 21.7 13.2 7.7 8.2 26.1 4.9 0.0 9.1 24.6 7.6 5.3 23.5 4.5 9.9 0.0 9.0 0.0 6.2 9.1 3.9 16.7 1.0 7.7 0.4 6.5 4.1 9.8 12.3 0.0 0.0 1.8 19.8 1.5 0.8 0.0 7.8 36.9 6.8 0.0 15.2 0.2 33.0 13.7 18.3 35.6 2.8 16.5 2.6 9.7 8.9 1.2 24.0 6.8 5.5 1.6 15.1 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 43.9 44.9 14.4 37.2 29.5 24.1 24.9 37.0 13.8 11.0 32.8 31.3 4.2 4.0 12.2 2.7 11.4 68.8 30.8 13.6 66.3 3.9 1.7 106.1 15.6 17.1 4.5 78.7 0.0 26.7 0.8 23.5 37.8 0.0 94.3 0.9 0.0 32.8 9.2 2.2 18.4 14.7 1.5 11.8 1.0 77.8 59.7 34.2 73.6 70.4 219.6 8.0 12.9 18.9 5.0 5.6 12.5 0.7 3.3 85.4 6.5 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 10.7;ASC TERT1: 13.4;EFO-21: 17.1;fHDF/TERT166: 10.6;SK-MEL-30: 10.7;U-2 OS: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1800000 Mitochondria "HPA012389: , HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 24.3 7.8 12.5 11.1 10.3 5.5 22.7 3.1 7.8 32.1 17.0 7.9 12.9 2.6 34.6 22.0 18.4 18.1 26.7 20.7 11.8 10.8 16.9 12.9 37.4 16.5 10.6 6.6 22.5 4.3 3.0 6.2 13.7 13.1 19.8 5.4 13.0 18.1 13.2 6.8 15.1 22.3 27.1 18.9 21.4 11.4 7.3 9.9 14.1 35.4 17.1 8.9 16.3 23.4 2.9 5.5 8.0 2.7 2.3 0.5 0.3 0.4 6.6 0.2 1.4 10.7 13.4 0.7 0.6 0.3 0.4 0.1 4.4 0.7 0.2 17.1 10.6 0.0 0.8 0.0 6.2 0.0 0.1 9.0 0.5 0.5 0.1 0.3 0.9 0.0 8.6 0.1 0.8 0.1 0.7 0.1 9.7 0.2 2.3 0.0 3.6 0.5 2.5 0.1 1.4 0.2 0.3 0.5 0.0 7.6 0.7 0.4 1.0 0.3 0.0 10.7 0.7 0.7 0.9 1.2 0.8 12.7 0.2 0.1 2.7 9.3 2.5 7.4 1.5 0.2 8.0 0.8 7.7 0.5 2.6 0.3 2.9 0.2 0.3 1.5 2.5 0.1 0.1 1.3 2.3 2.7 5.5 0.4 0.3 12.5 10.3 3.1 7.8 11.8 10.8 10.6 6.6 13.1 9.9 26.8 17.1 39.8 83.5 59.4 4.0 32.5 38.2 33.5 17.0 78.5 27.5 13.7 150.9 113.3 87.7 94.4 114.4 0.0 28.5 24.3 96.9 77.4 109.8 27.2 186.9 0.0 143.9 57.7 101.8 14.7 167.1 97.2 97.8 79.4 47.6 79.4 71.2 98.2 143.9 116.9 22.9 103.5 127.7 2.6 12.4 51.8 15.1 33.1 63.1 53.8 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769717-45782552 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.6" "Cell type enhanced" "Detected in many" 9 "Sertoli cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 44.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol NA NA Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 9.0 18.7 5.1 9.7 6.3 1.7 4.9 8.8 6.2 16.5 23.4 4.4 15.6 8.7 21.2 15.0 31.2 13.7 20.3 56.7 5.0 5.3 4.9 2.2 6.5 4.1 4.8 6.5 8.4 33.3 3.1 10.7 6.8 5.6 16.3 3.8 22.0 6.1 19.7 79.6 5.1 11.3 65.1 4.2 5.3 12.0 5.9 4.0 1.1 6.1 36.6 5.0 44.9 8.2 1.5 0.0 0.0 0.8 0.3 2.2 0.0 7.2 10.2 12.1 7.5 8.2 11.5 7.3 16.4 12.1 6.6 6.4 1.2 3.9 2.3 2.5 18.7 5.3 10.7 3.5 1.6 2.5 11.4 10.7 0.9 12.7 1.7 8.0 0.1 4.1 16.6 5.7 5.7 2.8 16.3 3.0 1.2 7.2 5.9 9.5 8.1 1.1 2.8 7.2 3.2 2.2 3.7 44.7 3.8 3.5 8.4 6.5 10.5 8.9 18.8 5.3 6.9 15.4 3.6 9.2 7.7 7.6 7.2 12.0 11.4 9.7 2.3 7.0 1.0 10.7 0.0 0.0 0.0 2.2 0.8 0.5 0.3 0.7 0.2 0.0 1.5 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.1 6.3 8.8 6.2 5.0 5.3 4.8 6.5 5.6 4.0 0.0 2.1 0.9 7.0 7.1 4.9 3.1 2.5 0.0 2.3 3.5 7.9 2.3 1.7 2.4 1.4 6.0 3.6 0.0 15.0 1.5 12.7 3.3 0.0 0.9 0.7 4.8 9.7 10.4 1.2 1.4 6.6 0.5 6.8 0.0 5.5 2.2 5.0 3.5 21.9 22.0 7.6 58.2 23.7 6.3 6.0 5.9 1.4 5.0 3.6 3.7 DPH5 CGI-30 ENSG00000117543 "Diphthamide biosynthesis 5" Q9H2P9 1 100989623-101026088 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046439, HPA076234" Approved Approved "Nucleoli,Golgi apparatus" NA NA "Golgi apparatus" Nucleoli "HPA046439: AB_2679667, HPA076234: AB_2797274" "unprognostic (1.31e-1)" "unprognostic (3.37e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (3.57e-2)" "unprognostic (8.59e-2)" "unprognostic (8.12e-2)" "unprognostic (1.37e-2)" "unprognostic (2.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.15e-1)" "unprognostic (7.09e-2)" "unprognostic (1.88e-1)" "unprognostic (9.00e-2)" 12.6 21.5 11.2 9.1 19.0 7.9 21.4 10.4 11.9 17.3 12.8 11.5 13.2 6.8 20.6 19.0 16.1 19.3 10.0 19.2 11.2 11.9 14.1 18.1 8.5 15.2 11.9 11.4 39.0 28.4 15.5 31.7 9.3 12.3 15.3 13.7 10.8 16.1 12.7 16.8 11.5 9.2 15.4 16.7 13.6 11.5 9.2 11.3 22.2 18.4 15.5 17.7 14.4 14.7 12.1 8.4 3.3 6.2 14.9 16.2 6.7 9.6 8.8 13.1 12.8 16.2 46.2 11.3 8.5 14.0 12.5 10.6 10.5 2.4 17.0 11.4 7.2 7.8 6.3 14.6 13.0 18.4 7.1 10.7 8.9 8.5 19.9 25.3 10.8 4.7 31.0 18.9 11.7 38.0 24.1 18.6 11.8 19.9 5.4 18.8 8.3 13.2 10.6 10.6 5.2 13.8 12.2 19.1 9.8 14.1 7.4 15.2 7.4 4.7 13.1 37.7 10.4 8.5 6.4 9.4 7.4 10.4 10.7 11.2 6.4 7.4 10.4 10.1 10.2 2.7 3.3 5.1 2.6 11.1 5.5 15.1 12.1 12.3 12.1 8.4 9.6 16.2 14.8 1.9 14.9 6.2 6.2 8.2 6.7 11.2 19.0 10.4 11.9 11.2 11.9 11.9 11.4 12.3 11.3 6.0 10.5 39.8 17.8 14.1 5.0 21.8 17.8 20.1 7.9 7.0 0.0 22.0 19.9 12.0 1.2 11.3 3.4 0.0 15.9 23.6 15.8 9.8 25.3 25.4 17.0 1.6 9.8 13.5 29.4 1.5 25.0 11.3 11.8 26.2 11.4 15.8 10.5 17.5 13.1 22.8 6.2 6.5 10.3 16.4 16.4 15.7 10.9 20.0 23.2 6.3 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211566 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Horizontal cells: 84.2;Melanocytes: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Approved Uncertain "Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Nuclear speckles, Intermediate filaments" Cytosol "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (8.73e-5)" 6.4 9.2 13.8 4.4 13.3 19.6 8.2 20.4 16.4 8.4 6.5 6.8 4.2 3.3 10.5 7.4 6.7 9.2 5.4 5.7 10.7 9.0 9.3 2.5 7.3 5.4 8.1 11.8 14.0 5.9 22.0 11.0 7.1 12.2 7.2 4.6 9.2 6.2 8.8 14.6 14.0 4.8 8.8 11.0 7.0 5.3 11.5 9.2 7.1 8.4 3.6 5.3 7.6 6.4 3.5 3.1 9.8 3.5 4.8 5.1 1.6 6.9 4.5 4.9 5.9 7.1 12.0 3.4 8.7 8.7 9.1 6.2 2.0 3.8 5.1 2.6 14.6 5.0 4.9 5.3 5.6 9.3 2.4 5.7 9.3 6.0 2.2 6.4 2.6 5.0 7.0 8.5 9.3 8.9 10.9 6.6 3.7 12.0 3.5 7.2 4.7 2.0 2.3 5.2 1.3 5.4 1.8 8.8 4.5 6.1 4.4 2.7 5.3 7.4 7.7 24.3 5.9 5.6 3.4 6.6 5.7 5.7 8.6 5.7 3.6 2.5 3.0 6.6 3.6 20.3 9.8 3.5 6.0 4.6 2.5 4.3 2.7 3.4 3.8 3.1 3.5 5.1 3.7 5.1 4.8 1.8 2.3 2.0 1.6 13.8 13.3 20.4 16.4 10.7 9.0 8.1 11.8 12.2 9.2 26.8 13.3 11.1 5.8 13.3 46.4 9.5 12.7 29.4 17.0 15.7 31.4 5.9 5.0 10.9 8.6 14.9 3.2 23.3 7.8 4.9 18.1 8.2 23.1 7.4 7.8 84.2 12.2 24.5 20.2 17.3 15.3 13.1 86.0 10.0 5.8 50.7 8.5 3.5 17.0 6.2 34.9 25.8 12.0 20.0 12.7 12.2 2.2 14.9 7.6 5.6 DUPD1 DUSP27 ENSG00000188716 "Dual specificity phosphatase and pro isomerase domain containing 1" Q68J44 10 75037836-75058514 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "skeletal muscle: 38.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042964 Uncertain NA NA "HPA042964: AB_10795764" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768090-172771195 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "neutrophil: 326.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 326.0" "Cell line enhanced" "Detected in many" "HHSteC: 43.7;hTCEpi: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol NA NA Nucleoli Cytosol "HPA069577: AB_2686156" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 158.4 78.0 12.4 68.5 14.0 89.7 91.8 17.4 14.9 81.4 37.1 32.4 48.5 9.4 55.4 71.6 82.7 94.8 138.8 49.2 12.5 11.4 29.8 115.4 135.0 43.5 30.6 9.7 69.4 34.4 26.6 40.8 93.7 29.3 67.1 34.2 61.0 38.1 192.8 54.8 116.1 27.6 65.0 29.5 36.1 53.6 45.9 18.7 10.8 90.4 104.1 46.9 69.0 109.7 2.4 11.5 326.0 31.8 4.5 9.8 14.0 2.1 5.5 1.7 2.4 38.1 22.3 2.9 35.4 10.3 23.8 9.6 6.0 2.6 0.7 10.3 24.8 27.4 0.9 1.7 8.7 11.2 19.4 4.7 0.4 12.0 2.5 43.7 0.2 0.8 21.3 76.4 10.8 17.6 12.4 7.4 1.5 1.8 13.9 15.3 2.5 1.1 1.0 1.5 1.6 1.6 41.1 3.2 6.4 16.9 1.1 7.5 3.1 9.6 16.3 1.2 7.6 1.4 0.4 19.5 16.9 8.4 16.4 2.7 2.9 1.6 0.6 15.1 0.3 0.6 33.3 24.6 69.8 3.9 25.0 9.8 2.4 3.5 4.0 11.5 2.1 1.7 1.9 326.0 4.5 31.8 0.6 2.8 14.0 12.4 14.0 17.4 14.9 12.5 11.4 30.6 9.7 29.3 18.7 381.2 398.8 474.0 769.9 1136.9 64.0 181.6 236.9 45.5 126.3 200.7 25.5 239.6 48.0 361.0 67.1 510.4 567.7 46.7 76.6 355.3 824.5 763.6 295.5 297.9 967.3 46.1 687.8 403.9 1172.3 21.1 356.4 1745.4 514.5 55.9 830.1 603.1 188.6 648.8 292.4 25.4 177.1 756.7 886.8 11.8 23.0 1710.3 486.7 546.6 309.1 534.2 DUSP10 "MKP-5, MKP5" ENSG00000143507 "Dual specificity phosphatase 10" Q9Y6W6 1 221701424-221742176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell type enhanced" "Detected in many" 9 "granulocytes: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 15.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 19.2;HaCaT: 42.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016758 Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No Nucleoplasm "Golgi apparatus, Cytosol" "HPA016758: AB_1847880" "unprognostic (1.55e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-1)" "unprognostic (6.65e-2)" "unprognostic (3.83e-2)" "unprognostic (2.85e-3)" "prognostic favorable (5.42e-4)" "unprognostic (2.89e-1)" "unprognostic (3.89e-2)" "unprognostic (9.68e-2)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (8.88e-3)" "unprognostic (1.97e-2)" 7.4 4.7 6.0 7.1 11.2 23.2 8.2 5.9 11.1 5.7 10.8 21.1 0.3 2.1 4.9 2.7 7.0 8.5 7.6 3.8 7.2 4.0 2.8 35.4 8.0 9.0 14.0 5.6 2.8 18.3 1.8 2.5 4.5 8.4 3.6 4.9 8.5 9.5 1.7 21.0 8.0 6.2 9.7 10.1 6.4 4.5 3.9 14.1 5.6 5.3 10.6 8.6 8.5 4.1 0.8 5.4 4.6 4.2 15.1 12.7 1.6 6.1 2.6 0.2 0.2 19.2 9.9 0.2 4.1 10.8 6.9 5.3 0.1 1.7 4.8 1.4 10.7 5.0 42.3 0.9 4.0 6.0 12.3 0.5 8.2 1.2 0.7 4.5 3.6 5.6 13.8 2.9 7.4 7.5 3.2 0.2 1.2 0.8 1.7 6.5 0.1 0.7 2.8 0.6 1.3 0.3 0.4 11.7 0.3 2.3 3.7 15.8 1.2 0.5 0.5 17.5 2.5 0.9 2.1 1.5 3.5 0.9 5.3 5.1 2.9 2.0 2.6 5.4 1.6 3.6 4.6 4.2 0.2 3.6 3.7 3.3 0.7 2.5 2.5 5.4 0.8 0.8 1.5 0.3 15.1 1.4 0.2 12.7 1.6 6.0 11.2 5.9 11.1 7.2 4.0 14.0 5.6 8.4 14.1 0.0 1.7 1.9 12.6 45.2 4.5 3.3 10.2 8.1 6.8 3.5 19.6 2.2 0.0 27.3 29.1 6.3 1.0 0.0 7.8 2.7 8.3 10.9 135.7 50.4 22.0 1.6 42.1 1.8 11.0 2.7 23.0 23.9 21.9 13.6 9.9 13.5 21.9 0.0 12.0 0.7 32.3 0.0 5.1 3.8 2.0 36.1 2.9 29.9 2.2 14.4 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 19.6 16.1 15.1 15.1 17.9 29.5 21.4 31.8 21.5 23.1 16.8 16.4 16.2 16.3 29.9 19.8 38.7 37.4 15.2 15.2 17.2 13.9 19.3 16.5 17.2 21.5 12.7 15.8 26.4 14.9 11.6 28.2 19.1 14.0 18.2 16.8 16.5 22.3 20.3 16.2 27.9 19.7 18.9 13.4 21.5 15.4 19.7 13.8 28.7 16.8 16.2 29.3 20.4 27.3 29.9 20.9 42.6 19.1 28.0 37.6 29.2 19.4 8.4 9.1 9.6 16.5 20.7 16.3 14.3 18.7 18.6 19.1 12.1 14.8 25.3 9.2 15.4 16.7 13.6 11.2 28.8 18.0 17.4 11.7 15.5 6.4 18.5 17.3 17.4 14.6 16.7 35.0 16.6 23.1 16.2 20.6 12.4 16.4 14.9 20.6 10.8 16.7 18.6 14.6 18.3 11.7 6.7 24.5 22.7 15.0 16.2 13.5 7.3 13.2 15.8 16.8 11.4 8.4 9.3 11.7 13.3 16.4 15.2 16.8 15.9 12.6 33.4 12.3 17.7 12.9 24.7 19.1 42.6 26.8 16.9 34.6 29.9 31.7 31.6 20.9 28.1 33.9 31.8 29.1 28.0 16.9 15.9 37.6 29.2 15.1 17.9 31.8 21.5 17.2 13.9 12.7 15.8 14.0 13.8 8.9 11.8 34.3 47.9 73.8 9.4 6.9 33.1 26.8 22.7 12.2 3.9 27.8 43.1 24.2 5.9 29.2 13.5 23.3 24.2 35.1 26.6 23.0 41.4 12.9 27.5 4.8 11.5 29.4 22.3 5.6 26.7 20.5 21.9 42.3 19.0 9.3 22.5 17.8 24.1 38.5 13.9 6.5 22.8 23.6 31.8 72.5 32.3 32.4 17.2 54.2 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavorable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 15.6 12.1 15.0 16.0 17.2 37.8 21.2 27.2 20.3 14.0 14.2 13.9 16.6 11.7 19.5 14.0 12.7 15.6 12.1 11.9 12.6 12.7 14.0 11.4 14.1 18.5 18.6 13.1 18.4 16.7 10.7 18.7 16.4 14.7 13.6 16.0 15.2 13.8 15.1 8.6 12.6 14.4 16.5 12.0 17.4 13.8 8.2 19.4 11.1 15.9 9.4 18.4 14.4 14.1 16.0 17.8 18.7 15.4 23.1 19.4 10.6 18.2 17.3 18.9 12.7 10.1 11.0 17.9 14.6 19.1 22.6 17.5 24.5 16.1 11.1 15.3 17.7 14.2 13.2 14.7 17.9 22.0 14.5 13.0 9.9 15.7 15.9 21.4 21.1 9.9 14.8 19.7 19.6 35.3 12.8 15.7 15.6 17.6 12.2 16.2 17.0 12.3 24.0 30.2 19.4 25.1 18.1 18.5 18.2 12.7 22.5 12.1 25.7 12.4 20.8 24.2 21.7 18.1 24.4 10.9 19.5 18.2 15.2 31.1 20.6 17.0 26.5 12.1 21.4 19.2 18.7 13.9 10.2 16.1 15.4 19.4 15.5 18.1 15.3 17.8 16.0 17.5 19.1 5.5 23.1 9.2 8.2 15.3 10.6 15.0 17.2 27.2 20.3 12.6 12.7 18.6 13.1 14.7 19.4 17.9 10.9 26.6 12.4 12.0 14.1 4.4 7.6 4.0 12.5 7.0 7.9 18.4 18.3 17.8 3.2 19.6 5.3 0.0 21.0 18.7 16.5 15.2 17.4 6.6 17.6 9.5 10.9 16.5 25.1 0.5 8.1 14.3 10.1 19.0 9.7 11.1 16.9 5.8 16.6 14.6 15.6 0.0 20.0 10.6 12.0 11.4 14.8 20.1 11.8 10.7 DUSP13 "BEDP, DUSP13A, DUSP13B, FLJ32450, TMDP" ENSG00000079393 "Dual specificity phosphatase 13" "Q6B8I1, Q9UII6" 10 75094432-75109221 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 75.2;testis: 18.6;tongue: 26.0" "Cell type enriched" "Detected in some" 6 "Early spermatids: 345.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39 "neutrophil: 3.9" "Lineage enriched" "Detected in single" 39 "granulocytes: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 5.0;EFO-21: 5.9;Hep G2: 12.2;K-562: 4.7;LHCN-M2: 10.9;RH-30: 9.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "unprognostic (1.79e-1)" "unprognostic (2.39e-2)" "unprognostic (2.39e-1)" "unprognostic (7.07e-2)" "unprognostic (1.66e-3)" "unprognostic (2.47e-3)" "unprognostic (8.63e-2)" "unprognostic (1.97e-1)" "unprognostic (2.63e-2)" "unprognostic (1.27e-1)" "unprognostic (3.92e-1)" "unprognostic (2.22e-7)" "unprognostic (1.93e-2)" "unprognostic (1.54e-1)" "unprognostic (4.81e-1)" "unprognostic (2.09e-2)" 0.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.2 0.0 0.0 5.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.3 0.0 75.2 0.1 0.0 0.0 0.0 0.1 0.0 18.6 0.0 0.0 1.0 26.0 1.9 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 5.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 12.2 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 10.9 0.6 0.0 0.0 0.7 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 1.4 0.0 10.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 345.5 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 54.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 2.6 2.7 1.8 2.5 0.0 0.0 0.1 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489831-37513501 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Basal glandular cells: 152.9;Basal keratinocytes: 159.6;Cytotrophoblasts: 141.3" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 10.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.7;HBF TERT88: 18.3;U-138 MG: 8.7;WM-115: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol NA NA 44000 "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavorable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 4.7 3.7 3.3 2.1 6.6 1.1 3.9 1.8 8.0 3.3 1.0 1.5 0.1 0.7 2.7 1.2 7.2 11.7 5.1 2.6 2.3 2.1 6.5 2.4 1.0 1.9 2.5 3.0 2.9 1.7 3.3 11.6 2.6 1.4 1.4 1.6 2.8 1.1 1.7 8.4 0.9 3.5 2.7 1.7 1.0 3.5 0.8 2.3 8.3 6.1 4.3 1.9 1.0 0.5 0.0 3.2 0.0 0.4 0.4 0.5 1.7 0.1 0.4 0.8 0.0 0.5 1.5 8.2 6.2 10.9 12.7 0.9 1.9 0.1 0.7 5.9 0.1 1.4 0.1 4.8 18.3 0.1 0.6 0.0 1.1 2.0 0.8 0.4 1.3 4.8 2.9 3.8 2.0 0.6 0.2 0.2 0.4 0.0 8.0 0.3 0.8 0.2 0.2 0.0 0.0 0.7 0.5 0.2 2.7 0.7 1.3 0.1 0.4 0.7 1.2 3.2 0.6 1.0 0.8 8.7 2.0 0.1 4.1 0.0 0.2 0.1 0.0 0.0 10.5 0.0 0.0 0.9 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.2 0.3 0.2 3.2 0.4 0.0 0.0 0.0 0.5 6.0 4.8 5.9 152.9 159.6 6.2 14.2 5.1 52.2 26.1 7.0 7.9 141.3 24.9 33.6 35.0 22.7 0.0 0.0 13.2 71.8 47.7 52.8 87.4 10.2 17.0 14.3 2.4 14.7 2.8 40.7 12.7 10.4 59.1 43.3 1.0 9.0 46.1 1.1 5.6 11.8 18.7 0.0 52.6 28.9 29.2 80.9 56.8 6.4 0.8 72.6 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 75.1" "Group enriched" "Detected in many" 5 "Distal tubular cells: 232.1;Early spermatids: 237.5;Late spermatids: 743.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive B-cell: 1.6" "Lineage enriched" "Detected in single" 14 "B-cells: 1.6" "Cell line enhanced" "Detected in some" "CACO-2: 5.4;REH: 17.7;SH-SY5Y: 5.1;SK-MEL-30: 4.4;U-2 OS: 4.3" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA076649: AB_2686811" "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favorable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.1 2.1 2.8 0.6 4.0 0.5 1.3 1.2 3.7 1.6 0.8 4.2 6.9 0.9 1.4 10.4 0.6 0.7 1.1 2.7 2.8 3.1 15.4 0.6 0.8 1.0 4.9 2.3 2.1 1.8 10.6 2.7 1.1 5.9 1.9 0.5 5.3 2.1 9.3 2.4 0.7 1.0 2.3 5.2 1.0 1.1 75.1 1.4 0.0 3.5 0.1 0.6 0.7 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.9 0.0 5.4 0.1 1.1 2.2 0.3 3.0 0.0 0.4 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.0 3.8 0.7 0.0 0.0 17.7 2.1 0.1 0.0 0.0 2.5 5.1 2.9 0.0 4.4 0.2 1.3 1.1 0.0 0.0 4.3 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.0 1.2 3.7 2.8 3.1 4.9 2.3 5.9 1.4 0.0 0.0 0.0 1.0 0.6 0.5 2.0 2.5 0.0 0.0 17.4 3.9 0.0 232.1 1.7 237.5 0.7 0.0 0.0 0.9 0.1 2.4 0.7 0.0 0.0 0.5 6.4 1.7 3.1 0.0 743.6 8.1 0.8 6.8 1.0 0.0 2.7 0.9 0.0 10.3 33.5 0.2 0.0 1.0 85.0 5.2 0.1 0.1 0.0 0.0 0.1 DUSP16 "KIAA1700, MKP-7, MKP7" ENSG00000111266 "Dual specificity phosphatase 16" Q9BY84 12 12474210-12562383 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 2: 56.3;Intestinal endocrine cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 6.9" "Lineage enriched" "Detected in many" 5 "T-cells: 6.9" "Cell line enhanced" "Detected in many" "NTERA-2: 23.7;RT4: 21.6;SuSa: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020326 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA020326: AB_1847890" "unprognostic (8.05e-2)" "unprognostic (9.47e-2)" "unprognostic (1.49e-3)" "unprognostic (4.14e-2)" "unprognostic (9.86e-2)" "prognostic favorable (1.01e-4)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.82e-1)" "unprognostic (2.34e-3)" "unprognostic (6.35e-3)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (5.76e-2)" 6.4 32.8 6.3 14.8 7.5 3.4 12.5 16.4 7.1 8.8 13.1 6.7 9.5 13.6 11.0 9.1 9.5 6.8 12.3 5.8 6.7 5.4 6.6 34.2 17.0 13.2 8.0 3.6 8.5 13.9 11.6 31.4 21.3 7.7 13.9 11.7 9.2 17.4 9.5 8.3 7.9 20.1 5.7 9.1 12.2 9.9 8.6 9.2 40.7 10.8 6.8 16.7 10.9 13.4 0.1 0.2 1.4 0.1 0.1 6.9 0.5 2.7 4.0 5.1 2.7 1.8 2.3 8.5 1.6 3.7 4.1 5.9 11.9 5.2 0.2 0.9 1.8 7.2 1.8 9.0 1.5 5.8 8.7 4.5 0.4 4.3 13.3 3.8 0.8 1.8 1.8 4.5 3.3 10.7 4.6 3.1 4.6 2.3 7.3 0.3 5.9 1.0 0.6 23.7 7.1 1.3 1.2 1.7 4.9 2.5 21.6 7.8 7.4 6.5 8.7 4.3 19.7 3.3 1.5 2.8 1.8 5.4 1.1 1.9 5.2 6.0 0.9 2.5 1.8 2.5 0.0 0.0 0.0 1.1 0.1 4.6 0.1 3.2 1.5 0.2 0.1 1.1 0.7 1.4 0.1 0.0 0.0 6.9 0.5 6.3 7.5 16.4 7.1 6.7 5.4 8.0 3.6 7.7 9.2 26.8 56.3 2.9 13.7 2.5 4.2 11.2 17.8 16.0 14.8 3.5 2.0 8.1 0.0 11.0 1.1 6.3 28.9 0.0 21.0 2.7 4.1 30.4 23.1 28.4 4.4 6.4 47.6 6.7 8.3 2.0 5.5 2.6 5.0 4.6 7.1 37.1 19.9 17.6 6.3 4.1 4.8 0.0 3.1 1.6 5.8 1.6 25.2 13.4 16.1 12.8 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667890 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "Early spermatids: 103.5;Late spermatids: 252.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No Nucleoplasm "CAB034070: AB_2094867, HPA051349: AB_2681450" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 5.2 3.9 10.1 7.1 9.7 4.9 5.3 4.1 8.3 5.6 10.1 11.4 4.6 7.8 6.1 8.4 7.5 18.5 8.0 3.8 8.7 7.8 5.5 2.3 9.9 7.2 8.4 3.9 4.4 6.6 5.2 19.5 3.6 9.5 4.6 11.5 4.7 6.1 4.3 2.0 7.9 11.0 6.4 9.0 6.9 8.3 30.8 10.2 8.0 5.8 3.4 7.6 6.0 6.1 6.4 11.2 21.7 13.9 4.3 8.1 4.7 5.3 5.8 2.6 6.5 6.6 13.1 2.5 5.1 5.9 5.2 5.6 3.1 5.7 3.5 3.6 6.4 6.6 4.0 1.6 4.1 5.8 10.0 6.4 1.8 2.0 2.0 2.8 7.5 5.9 3.7 5.8 8.6 3.1 5.8 15.9 4.3 1.8 3.2 5.6 4.6 4.1 1.8 1.0 6.6 3.5 3.0 1.7 1.3 6.3 3.7 6.7 3.8 5.3 2.1 3.7 3.6 4.7 2.1 11.4 10.7 5.8 2.7 2.9 2.3 2.7 1.8 12.1 1.3 5.4 18.3 10.4 19.4 5.9 12.5 4.6 6.4 6.8 5.4 11.2 6.2 4.6 5.5 21.7 4.3 13.9 6.4 8.1 4.7 10.1 9.7 4.1 8.3 8.7 7.8 8.4 3.9 9.5 10.2 17.9 4.8 6.0 10.2 19.1 2.6 1.9 7.6 64.3 11.4 5.2 43.2 1.0 3.3 7.4 103.5 9.0 14.8 0.0 8.2 3.0 9.3 7.5 6.9 0.9 7.3 1.6 34.1 9.8 12.7 252.1 7.8 16.2 8.5 6.4 18.0 9.2 7.0 14.0 6.3 3.0 16.3 6.5 7.2 68.7 18.8 18.6 0.8 8.6 18.5 6.4 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100005 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Ciliated cells: 20.1;Early spermatids: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Yes No Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 2.8 4.6 9.2 2.0 16.3 1.0 3.0 2.9 9.6 3.4 4.7 2.2 3.8 3.5 6.8 9.2 4.2 8.4 3.5 7.4 17.4 3.4 4.7 3.0 3.4 2.3 3.3 6.8 4.4 4.3 7.7 10.6 2.7 3.7 4.2 3.0 3.0 2.8 5.4 3.8 3.4 3.0 8.6 2.9 4.0 9.1 10.4 4.7 6.2 4.6 1.1 1.9 4.0 2.7 4.1 1.5 2.0 0.8 2.2 3.2 1.3 0.1 2.4 2.9 1.4 3.9 2.2 0.0 1.1 1.8 4.6 1.6 2.3 3.0 1.0 6.0 1.2 3.3 0.3 5.7 0.8 3.5 5.8 3.2 10.6 1.8 1.6 1.7 2.6 6.5 1.7 0.5 2.3 1.1 2.9 2.6 0.0 3.1 1.6 2.7 1.0 5.0 2.5 2.4 1.0 2.0 4.9 4.5 0.3 1.0 1.1 3.6 1.5 4.0 1.7 2.9 0.2 0.8 1.0 2.0 2.5 2.1 1.7 0.9 2.0 2.4 0.1 3.1 0.4 3.7 2.0 0.5 1.9 2.3 0.8 2.3 4.1 2.1 3.1 0.6 2.2 2.7 2.7 1.3 2.2 0.4 1.5 3.2 1.3 9.2 16.3 2.9 9.6 17.4 3.4 3.3 6.8 3.7 4.7 0.0 2.7 1.7 1.2 0.9 1.7 6.5 2.5 20.1 2.3 1.8 2.0 2.0 5.0 0.6 10.4 1.0 1.6 0.0 0.6 1.2 1.3 0.9 1.1 1.0 0.6 1.6 2.4 1.8 0.6 4.6 1.7 0.1 0.0 1.8 2.0 4.5 0.5 2.5 2.5 2.3 1.0 0.0 1.4 4.7 3.1 1.4 0.6 0.0 2.1 1.3 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143166-96145440 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 151.1" "Cell type enhanced" "Detected in many" 12 "Melanocytes: 136.7;T-cells: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "gdT-cell: 46.1" "Group enriched" "Detected in all" 10 "NK-cells: 29.6;T-cells: 46.1" "Cell line enhanced" "Detected in many" "Daudi: 15.3;HeLa: 13.9;JURKAT: 14.2;Karpas-707: 17.5;NB-4: 14.5;RT4: 17.4;SCLC-21H: 15.5;U-698: 21.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Nuclear membrane" Nucleoplasm "HPA071920: AB_2686472" "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 6.4 3.1 2.0 13.1 4.3 51.3 2.9 1.3 4.3 4.8 3.9 1.9 7.9 0.8 4.3 18.3 4.1 3.0 8.8 7.4 3.0 1.4 5.5 3.4 15.9 19.0 1.8 0.8 3.0 1.7 0.4 14.6 0.6 2.0 10.7 1.1 2.8 2.0 151.1 1.8 9.8 4.7 3.7 1.6 16.4 2.1 3.3 0.7 43.4 2.4 2.6 12.2 24.6 14.1 3.9 2.3 1.4 2.2 29.6 46.1 7.5 1.5 0.0 0.1 0.1 0.2 0.3 2.3 1.9 0.0 2.8 2.7 4.4 0.3 15.3 5.6 2.1 0.0 1.1 3.8 0.0 0.5 0.2 0.0 0.3 13.9 0.0 1.0 6.3 1.3 0.5 1.0 0.4 0.0 0.0 0.0 14.2 0.0 17.5 0.1 2.6 12.5 14.5 3.4 0.4 5.4 0.0 0.2 12.1 0.1 17.4 15.5 0.8 0.7 0.2 2.8 0.0 1.0 7.2 0.0 0.0 4.1 0.0 0.9 1.2 1.8 21.0 0.0 6.9 0.1 0.5 0.9 0.2 46.1 2.2 22.6 3.9 11.4 41.4 2.3 2.6 7.8 23.9 1.4 29.6 1.8 0.6 3.4 7.5 2.0 4.3 1.3 4.3 3.0 1.4 1.8 0.8 2.0 0.7 0.0 10.6 47.7 90.1 86.0 22.1 33.5 2.5 0.0 1.2 8.7 21.6 0.8 1.7 0.9 0.7 8.2 3.3 0.0 1.2 1.1 24.2 63.5 105.8 2.8 75.6 0.0 84.2 8.6 27.5 0.7 1.7 90.7 136.7 0.0 12.3 1.3 0.9 2.9 1.8 1.0 2.5 0.0 35.3 0.5 4.3 95.9 1.4 346.4 21.8 28.5 DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844004-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "testis: 15.9" "Group enriched" "Detected in some" 54 "Early spermatids: 58.8;Late spermatids: 167.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 1.7;K-562: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (5.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.1 0.6 0.0 0.0 0.0 0.0 0.0 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 71.9;U-266/70: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 24.8 13.1 22.0 24.6 31.3 19.4 28.7 12.1 27.5 18.1 29.0 29.8 18.8 21.2 20.6 25.2 29.8 15.0 20.4 31.0 22.6 17.4 16.0 20.3 24.6 27.4 33.5 16.1 13.9 27.9 10.8 14.8 25.9 25.5 16.1 15.9 16.9 20.9 15.5 32.0 30.6 21.8 23.4 29.2 30.0 21.4 41.3 30.0 9.2 19.9 19.0 27.9 22.8 27.4 21.6 18.0 16.3 17.5 2.9 8.2 9.8 3.6 2.2 4.8 7.2 5.6 6.2 6.4 2.7 2.2 2.4 2.9 2.4 4.1 7.7 6.6 2.8 5.1 2.5 6.0 5.0 1.7 18.4 6.9 5.2 1.8 6.6 2.8 1.8 6.8 4.6 15.2 1.7 3.2 4.0 6.8 6.6 4.8 25.7 2.0 2.1 2.7 6.7 2.9 2.7 5.2 5.4 3.3 71.9 4.5 1.6 8.3 3.2 2.3 0.9 7.9 11.0 4.9 2.4 9.3 2.2 2.9 2.2 1.6 36.6 25.8 10.7 0.8 5.1 4.9 16.3 17.5 6.9 5.0 14.0 3.5 21.6 3.9 5.1 18.0 17.5 3.6 5.1 12.0 2.9 12.6 15.4 8.2 9.8 22.0 31.3 12.1 27.5 22.6 17.4 33.5 16.1 25.5 30.0 14.9 17.6 38.7 19.8 23.6 5.2 35.3 10.2 26.8 25.0 5.2 0.0 9.1 18.3 21.3 11.0 33.7 13.8 0.0 45.0 6.9 17.8 14.6 32.3 22.1 25.5 0.0 9.1 22.7 40.0 14.8 14.4 35.8 43.9 83.8 13.0 9.8 28.3 14.0 8.9 14.6 2.6 25.8 27.2 30.7 73.7 32.4 5.5 15.0 14.5 23.5 DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.0" "Cell type enhanced" "Detected in many" 8 "Exocrine glandular cells: 394.0;Proximal tubular cells: 620.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HSkMC: 46.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA028211: AB_2672522, HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" 25.0 28.0 7.6 9.3 10.5 11.2 27.3 4.4 9.0 15.5 15.9 5.9 6.6 17.2 12.2 15.0 21.2 10.9 12.6 14.9 7.8 5.2 88.0 80.8 12.1 15.4 8.5 4.6 12.3 21.5 12.5 4.3 7.4 9.6 18.0 9.1 9.5 37.8 10.9 32.8 15.8 16.1 7.7 9.6 8.7 11.0 9.7 7.3 5.7 27.0 17.4 11.4 10.5 19.1 13.6 59.7 49.9 43.2 21.3 24.0 24.0 12.2 13.2 0.1 0.0 12.9 11.1 0.1 5.0 4.1 5.9 4.6 5.4 14.1 0.0 30.0 5.5 1.3 0.5 3.4 4.5 3.2 3.0 1.5 16.9 4.8 0.0 19.3 10.2 13.0 46.8 12.3 3.8 13.9 4.3 22.6 0.0 7.7 6.2 8.3 22.2 1.0 0.4 22.9 22.1 18.9 0.0 0.0 5.8 7.2 2.1 5.8 12.8 9.1 20.0 23.4 2.4 12.9 16.0 16.5 4.9 0.2 0.6 0.0 4.4 10.3 0.1 8.3 8.2 3.7 20.0 43.2 49.9 24.0 33.4 13.3 13.6 18.1 22.5 59.7 9.8 11.0 16.4 43.2 21.3 22.1 13.6 15.7 24.0 7.6 10.5 4.4 9.0 7.8 5.2 8.5 4.6 9.6 7.3 38.7 65.7 25.0 97.5 66.2 8.4 26.4 94.3 38.8 83.0 48.8 5.9 13.5 222.2 148.8 39.6 154.1 106.2 0.0 394.0 20.1 31.9 94.9 53.1 219.9 155.2 1.6 34.0 66.3 86.6 5.5 24.5 94.8 40.5 32.5 101.6 59.7 258.6 101.7 14.9 620.9 7.1 12.9 32.0 3.2 13.0 65.1 4.8 43.7 91.6 102.1 DUSP26 "DUSP24, MGC1136" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591332-33600106 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 147.1" "Cell type enhanced" "Detected in some" 12 "Bipolar cells: 76.1;Cardiomyocytes: 54.3;Cone photoreceptor cells: 39.3;Rod photoreceptor cells: 58.5" "Cancer enhanced" "Detected in some" "glioma: 6.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 16 "B-cells: 1.5" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 1.3 9.3 11.5 1.4 13.1 1.1 1.2 18.2 14.8 1.1 1.7 4.2 0.0 2.4 1.5 3.4 3.0 2.3 1.5 20.1 9.1 15.9 1.6 1.0 1.7 1.1 10.6 8.8 15.1 2.2 1.0 14.0 1.0 7.6 2.6 1.5 4.4 1.5 1.3 147.1 1.0 1.9 2.0 10.0 1.2 2.6 1.6 3.8 0.0 1.1 27.0 1.3 1.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 46.2 11.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 13.1 18.2 14.8 9.1 15.9 10.6 8.8 7.6 3.8 0.0 0.0 0.0 0.2 0.0 76.1 54.3 0.0 0.0 0.0 0.0 39.3 0.0 18.3 0.3 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 23.8 24.6 0.0 0.0 4.4 0.0 0.0 1.7 0.0 0.0 13.3 1.6 0.0 5.6 0.8 58.5 0.0 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 DUSP27 ENSG00000198842 "Dual specificity phosphatase 27, atypical" Q5VZP5 1 167094045-167129165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "heart muscle: 46.8;skeletal muscle: 64.8;tongue: 18.2" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 131.1" "Group enriched" "Detected in many" 6 "colorectal cancer: 12.8;stomach cancer: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RH-30: 18.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA012912 Approved Nucleoplasm NA NA Nucleoplasm "HPA012912: AB_2668767" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.44e-3)" "unprognostic (1.22e-1)" "unprognostic (2.10e-3)" "unprognostic (4.65e-2)" "unprognostic (1.53e-1)" "unprognostic (8.19e-2)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.72e-1)" "unprognostic (7.65e-2)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" 2.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.1 46.8 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.0 0.9 0.0 64.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 18.2 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 131.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240564014 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favorable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.8 2.8 2.7 3.0 3.4 7.9 3.5 6.3 3.7 3.1 2.6 3.3 6.5 2.9 2.6 5.0 3.5 3.1 4.4 16.3 2.8 2.7 3.2 3.4 2.5 6.1 3.5 2.4 2.6 10.2 2.6 5.0 3.2 2.8 4.3 2.8 2.7 3.7 2.4 21.2 4.9 4.2 4.3 2.2 5.9 4.2 8.2 2.3 2.6 4.4 13.4 4.2 2.8 4.5 3.8 3.3 10.7 2.1 2.7 3.3 2.0 1.7 1.6 2.2 2.6 1.4 0.8 2.4 1.9 1.2 1.5 1.1 1.0 4.5 2.7 1.0 1.2 2.3 5.1 1.7 0.7 1.6 3.4 6.4 3.9 3.4 2.5 1.0 2.5 6.7 1.7 1.8 1.0 1.3 2.9 0.7 3.9 2.7 3.3 1.3 1.9 3.1 4.0 1.4 2.6 1.4 3.8 4.8 3.6 1.1 2.9 4.9 2.7 1.8 1.9 2.2 1.4 2.4 4.4 1.7 3.5 2.9 2.2 1.7 13.2 3.8 4.4 2.2 1.9 2.8 10.7 2.1 0.7 2.7 1.4 3.0 2.1 2.8 2.8 1.2 3.8 3.3 3.0 3.6 2.7 1.5 3.3 2.2 2.0 2.7 3.4 6.3 3.6 2.8 2.7 3.5 2.4 2.8 2.3 0.0 5.0 5.1 6.9 3.3 6.3 12.9 12.7 6.7 1.2 12.2 3.9 6.4 13.3 4.1 27.6 3.1 11.8 0.0 5.1 4.0 4.1 8.4 6.9 6.6 10.0 7.9 8.1 2.5 10.3 29.8 2.8 7.0 6.8 8.2 8.1 7.4 3.9 11.8 1.4 11.2 6.6 6.5 5.6 41.1 17.6 4.6 5.8 12.5 10.1 6.8 DUSP3 VHR ENSG00000108861 "Dual specificity phosphatase 3" P51452 17 43766121-43778988 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.9" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 19.5;granulocytes: 5.2;monocytes: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063616 Supported Nucleoplasm,Cytosol NA NA 1300000 Nucleoplasm Cytosol "HPA063616: AB_2685061" "unprognostic (1.52e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (1.04e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.83e-2)" "unprognostic (8.98e-2)" "unprognostic (5.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.40e-3)" "prognostic favorable (5.49e-5)" "unprognostic (2.67e-3)" "unprognostic (5.45e-2)" "unprognostic (1.94e-1)" "unprognostic (1.37e-2)" 17.1 17.8 23.1 10.2 20.8 4.6 22.0 14.3 28.6 12.8 28.4 11.1 16.7 13.4 17.5 18.7 23.6 10.6 19.3 64.0 21.5 18.1 27.1 39.9 17.2 9.0 17.6 19.1 9.1 19.2 27.5 11.4 15.0 17.1 22.6 13.1 14.3 11.1 36.6 106.9 8.9 15.2 31.1 12.7 14.5 19.6 8.0 10.8 1.2 13.9 22.8 6.5 20.7 24.1 1.7 19.5 5.2 17.0 0.9 1.7 5.8 10.5 19.2 7.4 7.9 21.6 11.6 6.3 8.0 19.2 18.8 22.8 18.4 7.1 1.6 12.7 15.0 39.0 9.2 11.4 9.8 19.9 3.6 8.7 5.3 8.8 15.0 26.4 0.6 5.6 10.7 17.8 14.5 12.6 20.6 13.1 5.4 4.8 1.8 21.9 7.6 2.7 2.7 3.4 15.1 14.0 3.4 22.3 4.0 26.1 11.2 4.1 7.5 9.4 6.3 23.6 21.3 28.1 14.9 13.6 21.3 14.5 30.2 13.2 9.8 13.0 0.4 25.3 7.5 7.1 5.2 17.0 3.5 1.0 8.9 1.7 1.7 1.5 1.2 19.5 1.6 1.2 1.1 4.1 0.9 10.8 8.2 0.9 5.8 23.1 20.8 14.3 28.6 21.5 18.1 17.6 19.1 17.1 10.8 23.8 16.8 7.2 42.9 19.9 16.3 242.3 48.4 14.7 9.1 40.1 23.6 14.4 34.9 42.9 73.8 32.1 42.0 0.0 50.5 17.5 18.4 41.2 38.1 99.4 73.0 19.1 34.9 27.6 34.5 128.1 13.6 40.3 10.1 32.5 17.6 14.8 50.2 28.1 24.8 69.4 16.6 32.3 35.5 2.4 2.9 25.2 37.6 6.4 14.6 32.8 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350668 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 46.7;pancreas: 78.6;seminal vesicle: 63.5" "Cell type enhanced" "Detected in many" 7 "Basal glandular cells: 94.6;monocytes: 131.7;Pancreatic endocrine cells: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "T-reg: 9.6" "Lineage enriched" "Detected in single" 18 "T-cells: 9.6" "Cell line enhanced" "Detected in many" "A549: 29.9;OE19: 27.1;SK-MEL-30: 46.1;WM-115: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm NA NA Nucleoplasm "HPA061967: AB_2684648" "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 10.9 3.4 1.2 3.6 1.1 3.4 17.1 4.8 2.7 4.6 1.7 1.0 46.7 0.8 3.2 0.7 1.6 1.3 13.1 1.5 4.6 0.8 0.7 0.4 3.7 1.8 0.8 0.8 1.2 78.6 0.1 3.7 17.7 0.7 4.3 0.9 17.1 8.9 63.5 2.7 3.5 1.3 1.5 1.1 0.6 20.6 1.7 0.2 3.9 1.2 2.0 4.7 7.4 3.0 0.0 0.5 0.0 0.0 0.2 9.6 0.1 11.1 29.9 17.8 0.8 2.2 0.0 1.5 2.3 12.7 7.0 3.1 0.3 5.7 0.0 6.3 1.0 4.9 3.6 0.2 7.7 4.2 0.3 0.6 0.0 1.0 0.2 0.0 0.1 14.6 1.4 5.1 2.1 13.1 15.4 5.7 0.1 0.1 1.3 14.0 12.6 0.0 2.0 3.1 27.1 18.4 0.3 0.5 2.3 16.1 5.9 0.1 9.8 3.2 15.2 46.1 0.3 3.2 0.3 16.0 5.1 0.0 0.0 1.6 3.5 0.4 0.0 15.6 2.6 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 9.6 0.1 1.2 1.1 4.8 2.7 4.6 0.8 0.8 0.8 0.7 0.2 0.0 3.2 1.4 94.6 10.8 34.2 1.9 28.1 29.4 15.9 0.0 11.8 2.7 0.0 64.0 3.5 10.8 0.4 0.0 66.9 37.5 8.4 20.9 5.8 0.0 19.5 41.3 93.8 19.6 5.0 19.7 0.3 25.0 62.4 131.7 7.6 0.9 166.3 0.0 0.0 0.0 2.8 12.9 12.2 0.6 0.4 10.5 14.9 8.5 2.2 92.0 DUSP5 HVH3 ENSG00000138166 "Dual specificity phosphatase 5" Q16690 10 110497838-110511544 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Basal glandular cells: 372.8;Urothelial cells: 958.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.4;non-classical monocyte: 8.8;plasmacytoid DC: 13.3" "Group enriched" "Detected in many" 19 "dendritic cells: 13.3;monocytes: 8.8;T-cells: 3.4" "Cell line enhanced" "Detected in many" "hTERT-HME1: 87.7;Karpas-707: 34.0;U-266/70: 48.5" "Region enhanced" "Detected in many" "cerebellum: 68.0" "Region enriched" "Detected in many" 5 "cerebellum: 41.9" NA NA "unprognostic (1.25e-1)" "unprognostic (3.57e-1)" "unprognostic (5.19e-2)" "unprognostic (1.03e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (8.30e-6)" "unprognostic (1.70e-2)" "unprognostic (4.60e-2)" "unprognostic (2.91e-2)" "unprognostic (1.20e-2)" "unprognostic (4.20e-3)" "unprognostic (3.79e-1)" "unprognostic (3.78e-3)" "unprognostic (2.32e-1)" "unprognostic (9.09e-2)" 13.7 11.0 2.8 12.4 5.1 14.5 11.2 19.8 5.2 15.1 12.5 3.3 7.7 5.4 9.1 8.8 55.5 5.6 24.2 11.3 5.2 3.3 9.1 13.1 12.1 9.3 2.9 2.8 6.5 3.9 5.5 8.0 45.1 5.6 15.6 12.4 21.0 9.4 10.0 1.8 6.5 17.6 10.3 7.1 11.4 10.2 13.1 2.1 4.8 7.8 21.9 47.8 31.6 14.3 0.2 13.3 0.4 8.8 0.0 3.4 0.5 4.4 3.0 0.6 1.5 2.4 10.2 2.2 10.6 24.0 5.7 6.9 1.9 6.0 0.5 2.0 2.5 12.2 1.4 0.6 5.5 9.3 12.7 0.3 2.4 0.5 1.1 9.1 0.6 3.2 3.9 7.6 18.2 87.7 2.5 3.5 0.2 0.4 34.0 17.0 1.2 0.1 1.8 2.0 0.4 4.6 0.0 1.3 7.8 19.5 8.7 0.3 0.8 0.7 1.7 3.5 5.7 0.9 0.7 5.5 1.9 1.3 4.6 5.0 48.5 8.6 1.2 7.5 3.3 1.3 0.4 0.2 0.0 3.4 2.0 1.2 0.2 1.8 1.0 0.9 0.0 0.0 1.1 0.1 0.0 8.8 13.3 0.0 0.5 2.8 5.1 19.8 5.2 5.2 3.3 2.9 2.8 5.6 2.1 3.0 8.5 17.2 372.8 58.6 8.2 28.2 7.6 0.0 18.2 33.2 5.9 30.4 5.0 26.2 1.0 35.0 36.5 0.0 4.2 9.9 26.3 104.8 3.5 4.0 9.3 0.0 46.8 165.1 18.3 1.9 1.4 20.8 150.1 76.7 7.8 2.5 31.7 14.0 0.7 0.3 10.6 0.0 31.1 1.0 9.1 89.1 114.9 25.9 7.6 958.4 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347232-89353271 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 125.0" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 270.1;granulocytes: 438.5;Kupffer cells: 216.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 125.0" "Group enriched" "Detected in many" 11 "granulocytes: 125.0;monocytes: 79.7" "Cell line enhanced" "Detected in many" "AN3-CA: 82.0;NB-4: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favorable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 37.7 7.5 7.2 15.9 11.7 41.3 24.1 3.4 14.7 11.6 12.4 6.2 5.8 6.1 9.8 8.7 12.0 15.4 25.1 16.2 10.5 6.5 17.1 38.4 28.2 13.3 6.9 7.4 7.5 12.2 15.0 13.7 19.7 7.9 17.4 15.3 44.4 64.3 6.3 12.0 8.5 14.6 11.3 7.1 28.4 10.3 4.8 6.4 6.1 21.0 13.3 17.8 15.2 6.9 1.2 9.2 125.0 79.7 1.2 0.9 32.4 1.1 1.1 24.4 82.0 21.1 18.0 0.0 8.8 11.2 1.8 1.3 7.2 1.3 0.0 2.1 3.7 3.4 9.4 0.1 22.0 2.5 0.1 0.1 3.6 0.2 11.4 15.0 15.7 40.2 3.5 7.7 15.5 14.5 18.4 40.7 0.4 0.0 3.8 5.6 0.5 0.5 58.8 14.8 28.0 20.0 40.0 3.0 1.5 25.2 23.7 0.4 17.4 0.2 0.1 46.7 8.7 1.2 8.8 10.9 6.0 0.1 1.1 4.2 0.6 3.2 0.1 24.9 11.1 38.0 125.0 49.5 22.4 0.9 79.7 0.4 0.2 0.2 0.3 9.2 1.2 0.1 0.3 22.5 1.2 74.4 1.2 0.6 32.4 7.2 11.7 3.4 14.7 10.5 6.5 6.9 7.4 7.9 6.4 95.3 270.1 20.5 66.1 80.7 1.2 8.1 53.5 22.7 111.5 171.0 31.4 63.9 14.9 10.9 1.1 97.2 31.9 0.0 11.9 2.9 29.6 20.6 438.5 128.2 43.3 1.6 18.4 173.1 216.2 1.4 1.4 140.4 11.8 1.8 11.0 9.0 12.3 7.4 3.2 23.5 2.0 25.8 8.5 1.2 1.1 21.7 41.2 18.5 12.8 23.4 DUSP7 "MKP-X, PYST2" ENSG00000164086 "Dual specificity phosphatase 7" Q16829 3 52048919-52056550 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 12 "Basal keratinocytes: 104.2;Suprabasal keratinocytes: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 41.4;hTERT-HME1: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073007 Approved NA NA "HPA073007: " "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (6.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (8.67e-3)" "unprognostic (7.38e-3)" "unprognostic (7.74e-3)" "prognostic unfavorable (8.84e-6)" "unprognostic (4.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "unprognostic (9.46e-2)" 5.5 5.9 7.8 4.3 8.5 1.6 3.7 6.5 19.2 8.6 2.9 15.3 3.4 2.4 5.6 2.4 22.0 4.4 5.3 8.3 7.3 4.8 3.6 2.5 7.0 5.6 9.9 10.0 4.7 4.3 3.9 3.8 8.9 4.9 4.0 2.3 4.6 5.2 5.3 11.4 24.1 3.5 4.2 4.8 10.7 3.7 5.4 9.2 3.2 3.4 15.0 8.6 5.8 14.7 1.0 7.5 1.7 10.7 2.3 8.2 1.7 7.6 1.6 1.9 4.4 6.3 5.5 2.3 7.7 14.8 7.7 5.6 2.1 3.9 2.1 2.1 11.4 3.9 9.0 7.4 28.0 5.3 1.8 3.0 10.0 3.9 3.7 5.1 8.9 6.1 5.7 41.4 9.9 35.3 5.3 7.3 6.2 5.7 6.1 6.1 2.1 6.6 12.7 4.8 2.1 14.0 5.6 1.7 5.6 3.2 3.3 2.4 7.2 3.4 3.2 5.4 1.6 1.1 21.6 9.5 14.9 9.6 15.6 23.5 2.9 2.7 3.4 8.2 15.1 4.7 0.9 3.9 1.7 6.0 10.7 8.2 1.0 7.2 4.3 5.0 0.6 5.3 4.8 1.4 2.3 10.0 7.5 4.6 1.7 7.8 8.5 6.5 19.2 7.3 4.8 9.9 10.0 4.9 9.2 8.9 0.6 1.5 23.5 104.2 4.7 15.3 0.0 1.4 5.7 0.0 0.0 0.4 1.7 3.3 1.1 11.3 0.7 0.0 2.3 3.4 9.0 3.2 0.0 0.4 6.7 0.0 2.4 28.3 10.7 0.0 8.1 8.3 20.3 0.0 2.9 0.9 7.4 0.0 4.6 0.9 1.0 25.8 15.1 3.2 4.3 118.3 1.0 4.5 2.9 24.4 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554044-1571920 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.2" "Cell type enhanced" "Detected in many" 10 "Bipolar cells: 101.5;Cone photoreceptor cells: 45.2;Horizontal cells: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;MCF7: 6.2;SH-SY5Y: 5.5;U-251 MG: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol NA NA Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favorable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.3 2.2 18.8 3.2 18.8 7.5 3.5 20.0 30.2 1.9 4.3 4.2 1.4 1.7 5.9 4.8 3.5 4.0 5.4 5.7 16.6 9.3 2.6 3.7 3.6 3.5 5.5 11.2 2.2 12.7 1.7 10.8 2.8 5.1 3.0 4.1 2.7 5.1 2.7 6.1 3.2 6.3 9.3 3.6 6.3 4.3 2.4 5.1 0.0 2.6 2.2 2.3 2.7 1.6 0.1 0.1 0.0 0.0 0.0 0.7 0.0 1.8 0.8 1.0 0.1 0.0 0.1 2.2 0.1 1.2 0.4 1.2 0.0 0.0 0.1 0.0 0.3 0.0 1.2 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.2 0.4 0.0 0.1 0.1 0.0 1.8 0.0 6.2 0.0 0.4 0.0 0.0 1.9 0.1 0.1 0.7 0.0 0.2 0.0 5.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.0 2.3 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 18.8 18.8 20.0 30.2 16.6 9.3 5.5 11.2 5.1 5.1 3.0 0.6 0.0 5.6 8.8 101.5 5.2 5.1 0.0 0.0 12.2 45.2 0.1 1.7 6.9 0.2 2.2 22.7 0.0 9.6 0.4 4.5 12.8 0.0 0.4 0.4 85.8 40.5 1.3 0.0 0.0 0.6 0.3 5.0 1.8 20.2 16.0 9.8 17.5 0.4 1.1 36.7 6.5 5.1 0.2 0.4 4.3 4.9 1.3 16.8 9.8 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "kidney: 23.0;placenta: 63.1" "Group enriched" "Detected in some" 14 "Cytotrophoblasts: 876.9;Distal tubular cells: 616.8;Syncytiotrophoblasts: 1451.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Hep G2: 90.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "amygdala: 4.4;basal ganglia: 2.7;cerebral cortex: 3.5;hippocampal formation: 3.7;hypothalamus: 3.6" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.1 3.2 0.2 4.4 0.1 0.3 0.2 2.0 0.2 0.1 0.7 0.0 0.2 0.1 0.3 0.3 0.2 0.1 0.2 2.5 0.6 23.0 0.7 0.2 0.2 1.1 0.6 1.9 0.5 0.1 0.0 63.1 0.9 0.2 0.1 0.0 0.8 1.5 0.1 0.2 0.2 0.1 0.5 0.2 0.2 1.1 0.8 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 8.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.6 0.5 0.0 4.0 0.0 0.3 1.8 10.1 0.2 0.0 0.2 1.8 0.0 0.7 90.8 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.2 0.2 0.4 3.7 0.0 0.0 0.0 0.0 2.3 0.1 0.3 0.6 0.7 0.3 0.2 0.1 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 0.2 2.0 2.5 0.6 1.1 0.6 0.9 0.8 0.0 0.0 0.0 0.6 0.6 0.0 1.8 0.0 0.0 0.0 10.4 0.0 876.9 616.8 0.1 0.0 0.0 0.0 0.0 0.0 57.4 0.2 0.3 0.0 0.8 72.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 0.0 0.0 0.0 0.7 8.3 0.0 1451.1 0.0 0.0 0.9 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 20.0 18.5 19.2 23.4 20.0 49.7 19.9 31.6 24.6 23.7 23.0 16.3 17.6 15.4 24.4 18.7 16.8 19.4 19.0 23.2 18.8 17.9 16.9 16.1 24.8 27.3 15.5 17.8 25.7 17.8 31.0 25.1 25.0 14.0 17.6 18.1 18.5 18.7 22.7 39.8 20.1 18.7 22.7 13.8 24.1 18.5 23.5 16.3 60.9 22.7 17.4 22.1 22.7 29.3 3.0 3.3 6.0 2.5 1.3 3.8 0.8 10.4 8.1 16.6 11.6 7.9 8.6 14.7 9.3 11.8 9.4 9.9 11.5 9.2 14.0 6.3 16.2 12.4 7.1 12.1 9.0 11.1 21.4 5.2 41.4 13.5 7.0 11.8 16.3 15.2 8.7 10.8 12.2 18.7 10.8 9.7 19.8 15.6 32.5 9.8 10.4 21.4 11.2 17.5 10.3 4.8 27.8 9.1 12.9 9.8 13.6 17.1 9.6 21.1 14.5 14.5 5.8 13.5 15.2 12.4 12.9 3.9 8.0 7.7 22.1 17.1 20.0 10.2 18.4 14.0 5.5 1.5 2.0 3.4 2.1 2.1 2.8 3.6 2.6 1.8 3.0 3.8 3.7 6.0 1.3 2.5 3.3 3.1 0.8 19.2 20.0 31.6 24.6 18.8 17.9 15.5 17.8 14.0 16.3 17.9 21.0 14.9 21.8 33.3 28.8 68.6 17.8 18.7 21.6 10.4 25.5 8.2 0.0 11.5 21.3 24.8 20.2 23.3 12.6 9.6 20.6 24.7 24.3 15.3 13.8 44.5 20.5 28.3 24.3 15.3 15.0 20.8 23.6 6.4 16.5 15.6 16.7 20.4 18.4 8.1 19.4 12.9 24.5 15.8 14.0 27.7 12.8 30.6 13.6 28.3 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.1" "Group enriched" "Detected in many" 14 "Early spermatids: 145.5;Late spermatids: 469.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No Nucleoplasm "Mitotic chromosome" "HPA028522: AB_2672656, HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favorable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 4.8 7.9 7.4 3.7 10.2 5.0 4.0 10.1 13.1 4.5 4.2 7.4 6.1 6.2 6.4 12.3 6.7 8.0 4.6 9.0 6.6 6.1 6.1 3.2 5.4 5.1 4.4 6.7 6.1 5.2 7.1 12.3 3.8 6.4 5.5 3.4 6.7 5.5 5.8 89.1 6.3 5.1 3.9 3.4 5.9 5.2 28.8 4.6 11.2 6.4 25.3 5.3 5.6 4.1 4.7 8.3 4.8 3.2 6.2 7.0 2.6 0.4 8.6 8.4 5.9 4.8 4.5 0.7 2.7 1.7 2.5 2.3 0.8 3.3 1.3 10.6 3.2 0.1 2.9 1.2 1.9 2.2 4.9 7.3 0.6 5.4 0.8 4.0 0.3 1.8 6.1 1.2 0.8 2.8 8.2 0.6 3.3 1.4 1.9 0.4 4.3 1.9 0.8 2.0 2.5 2.0 0.9 0.1 0.6 5.4 2.1 12.2 13.8 4.2 4.2 0.2 4.7 4.1 0.5 4.2 1.1 1.9 0.9 0.8 3.1 1.0 0.9 7.1 0.8 0.4 1.2 3.1 3.2 5.9 3.2 7.0 4.7 4.0 5.9 3.5 3.5 2.2 3.5 4.8 6.2 2.9 8.3 4.2 2.6 7.4 10.2 10.1 13.1 6.6 6.1 4.4 6.7 6.4 4.6 0.0 1.1 13.7 3.6 3.1 14.9 5.3 5.1 1.4 0.0 15.7 19.6 1.8 8.3 11.7 145.5 5.7 9.1 0.0 3.7 1.5 4.0 5.4 1.1 3.0 4.9 9.5 19.5 6.2 9.2 469.8 6.6 2.7 5.0 3.6 9.4 8.1 8.6 8.6 4.9 11.2 13.0 0.0 2.3 22.4 14.0 2.5 1.1 6.9 8.5 3.2 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 72.1;Horizontal cells: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: AB_2683271" "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 12.2 5.3 4.5 20.1 4.8 8.6 8.1 4.4 6.6 10.1 21.3 4.1 8.3 13.7 14.6 9.6 9.6 9.1 16.9 26.1 4.7 3.2 6.3 4.6 10.1 17.9 4.0 3.3 7.6 8.5 3.6 4.4 13.0 5.0 7.1 15.3 6.6 7.2 6.6 23.7 9.4 26.0 11.2 5.3 10.3 14.0 4.4 3.9 34.3 7.6 12.5 17.2 11.1 12.2 2.7 1.9 5.9 1.3 6.9 6.8 1.6 13.8 7.8 11.7 8.4 5.9 8.1 9.4 14.1 9.2 6.9 3.9 10.3 7.7 25.8 17.4 20.3 4.2 16.1 9.3 5.5 7.4 11.1 12.2 4.1 5.2 3.9 2.3 9.4 9.1 6.6 7.9 18.6 14.9 11.7 3.8 11.0 5.1 13.5 8.8 7.9 8.0 4.6 10.1 9.0 12.6 21.5 11.6 11.4 8.0 17.4 15.5 18.3 5.9 7.9 8.1 8.3 5.4 7.9 5.7 11.0 10.4 7.5 11.1 6.5 1.0 14.3 10.5 6.4 11.3 3.2 0.5 5.9 5.2 1.3 4.0 2.7 3.9 6.8 1.9 2.7 3.3 6.1 0.7 6.9 1.3 0.8 3.1 1.6 4.5 4.8 4.4 6.6 4.7 3.2 4.0 3.3 5.0 3.9 8.9 12.2 6.4 9.1 10.1 17.2 33.5 22.9 12.0 10.3 1.8 21.6 2.7 0.0 17.2 0.4 10.5 72.1 0.0 15.8 6.4 18.2 11.3 5.7 4.7 14.1 76.3 23.6 6.2 11.6 1.6 10.6 9.8 8.5 6.4 50.5 15.3 15.6 48.2 12.4 7.5 21.9 12.9 21.1 2.5 8.7 14.2 3.8 21.0 26.7 28.1 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell type enriched" "Detected in many" 6 "Early spermatids: 160.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 6.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.1" "Cell line enhanced" "Detected in many" "hTERT-HME1: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075041 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA075041: AB_2686730" "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.1 2.7 4.2 4.2 3.5 6.2 7.7 1.3 2.7 5.6 2.7 2.6 3.7 1.2 7.6 5.1 2.7 6.2 12.8 16.3 6.0 3.4 3.4 7.4 5.0 1.6 2.6 2.0 7.6 5.2 2.8 11.2 1.2 4.6 4.5 1.5 4.1 5.5 3.0 2.1 2.0 2.1 7.5 2.7 1.8 3.7 38.2 3.1 5.1 11.9 3.0 1.7 5.4 7.6 0.0 6.1 0.0 0.1 0.0 0.3 0.0 2.5 3.5 0.8 4.9 8.7 7.8 0.1 8.2 18.1 7.5 9.7 0.2 1.3 3.7 1.2 9.6 13.2 0.7 4.2 6.6 8.0 0.0 2.8 5.4 4.4 0.8 13.8 3.7 3.5 5.5 4.3 12.9 35.7 7.7 5.8 5.7 10.4 0.7 11.5 0.9 8.2 2.1 6.9 0.2 6.5 20.4 2.6 0.0 2.4 0.1 5.0 3.7 7.3 0.3 10.0 1.0 0.9 0.9 4.3 15.7 5.9 7.6 6.8 2.9 1.1 4.4 9.3 4.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 4.2 3.5 1.3 2.7 6.0 3.4 2.6 2.0 4.6 3.1 3.0 5.1 0.5 10.3 5.8 0.1 10.3 2.5 13.4 5.7 1.8 9.8 0.0 0.0 3.0 160.9 4.2 0.0 0.0 1.9 0.1 7.3 3.2 0.0 1.1 0.9 0.0 2.4 2.5 1.5 27.7 3.7 1.9 8.5 1.8 0.3 3.0 1.4 0.0 1.8 1.0 7.4 6.5 10.3 17.6 3.4 3.1 0.3 0.0 0.2 3.5 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 85.9" "Group enriched" "Detected in many" 7 "Early spermatids: 369.7;Late spermatids: 289.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028065, HPA056073" Enhanced Enhanced Vesicles No No Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 1.6 2.1 2.3 2.1 1.8 1.6 2.8 1.9 2.3 2.6 2.1 2.2 2.3 1.7 2.5 9.1 1.6 2.0 1.7 1.7 1.8 1.8 1.9 2.0 2.2 2.5 1.9 2.5 2.2 2.3 2.9 2.7 2.9 2.3 2.3 2.7 2.4 2.3 3.4 1.6 1.9 2.4 2.1 2.7 4.3 1.7 85.9 2.1 1.6 4.3 1.6 2.0 2.4 1.6 7.6 2.7 1.3 5.2 1.1 1.6 1.6 1.9 3.0 3.8 4.1 5.8 7.2 4.6 2.3 4.6 5.3 5.8 0.6 3.1 5.7 0.3 6.5 3.6 4.0 2.9 4.3 4.2 4.3 6.6 4.0 0.8 3.3 16.4 3.4 3.2 4.9 9.2 3.7 12.2 9.9 7.4 6.3 1.6 6.5 4.7 4.0 3.2 8.5 5.2 1.0 1.7 0.7 2.7 2.4 6.4 1.8 0.0 1.5 0.4 2.3 3.3 8.7 1.8 3.1 0.5 6.2 4.9 0.6 2.9 1.9 2.3 3.4 3.3 5.4 3.2 0.6 2.8 1.3 1.0 2.2 1.1 7.6 1.5 1.6 2.7 5.8 1.6 1.6 0.1 1.1 5.2 1.4 1.1 1.6 2.3 1.8 1.9 2.3 1.8 1.8 1.9 2.5 2.3 2.1 11.9 14.4 11.1 13.1 7.9 20.7 19.4 5.1 12.0 13.6 15.7 9.8 12.9 26.6 22.0 369.7 9.3 4.0 0.0 23.8 10.1 17.5 12.6 17.3 9.2 41.7 12.7 5.2 9.2 15.7 289.4 14.1 15.9 15.1 18.0 47.3 16.6 22.1 15.8 29.7 28.1 17.0 6.5 15.6 20.0 31.5 6.6 8.2 17.3 15.6 9.8 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589682-108694846 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 57.4" "Cell type enhanced" "Detected in many" 10 "Ciliated cells: 183.4;Cone photoreceptor cells: 308.3;Spermatocytes: 314.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles No No Vesicles "HPA035066: AB_10601549, HPA049232: AB_2680684" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favorable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 4.6 9.3 14.1 4.5 25.7 3.1 5.0 14.5 23.7 5.2 4.4 5.8 2.1 2.8 7.4 9.7 3.8 17.4 5.4 10.8 13.2 18.5 10.5 3.9 6.0 8.4 10.3 16.0 10.3 4.9 10.3 57.4 4.5 20.3 9.2 4.5 4.0 3.3 7.0 10.1 3.4 3.6 7.9 9.2 7.0 6.0 29.9 8.0 10.4 12.0 2.8 7.0 5.0 3.5 6.8 1.8 5.2 1.6 11.7 6.5 1.8 6.5 6.0 17.0 10.2 7.6 7.9 5.8 4.1 8.2 6.9 9.4 8.3 4.5 11.8 8.9 4.4 14.9 2.4 9.7 3.5 14.7 4.3 4.1 5.4 2.2 5.7 4.5 2.1 3.1 8.2 1.9 6.4 8.0 7.1 4.3 7.6 5.1 5.8 13.1 5.9 5.3 2.3 10.4 3.4 4.3 6.8 14.0 1.1 5.8 3.2 11.5 11.0 6.9 0.7 7.4 16.0 10.2 1.8 4.9 6.2 9.5 1.2 3.6 6.7 3.8 23.0 4.7 1.7 7.5 5.2 0.7 1.4 5.0 1.0 6.0 6.8 5.1 6.1 0.6 6.0 4.5 6.0 0.1 11.7 1.6 1.8 6.5 1.8 14.1 25.7 14.5 23.7 13.2 18.5 10.3 16.0 20.3 8.0 11.9 13.8 8.3 8.5 6.6 67.2 33.6 2.5 183.4 29.6 31.4 308.3 19.8 11.6 8.1 23.6 8.2 3.9 0.0 8.1 7.3 13.9 8.8 8.1 3.6 7.8 73.1 50.7 6.7 7.3 46.6 16.1 6.2 6.8 14.4 6.1 33.9 8.4 3.5 16.6 15.3 32.1 19.4 9.2 314.4 93.7 6.5 12.4 18.5 6.3 4.3 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38832005 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 5700000 Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 33.0 52.0 17.6 21.7 20.9 14.7 29.6 11.4 19.8 14.8 34.1 19.5 19.8 25.8 16.8 15.4 30.2 18.9 30.6 130.6 18.6 15.5 40.0 105.8 16.9 19.6 22.2 17.2 16.0 36.5 11.5 11.3 32.8 17.5 20.9 27.1 20.8 27.4 15.2 130.9 18.7 24.4 27.0 13.3 28.1 24.8 26.2 20.6 15.9 24.5 43.5 21.5 21.3 19.3 68.7 60.7 49.9 61.1 61.4 72.6 83.3 12.6 55.6 8.6 14.3 33.7 17.5 12.7 6.2 10.9 5.5 5.6 35.7 25.1 19.8 24.5 14.7 5.0 6.0 14.4 14.9 4.3 68.5 8.0 24.0 16.9 28.8 34.3 25.4 24.3 23.2 38.6 7.2 12.5 10.9 13.0 26.2 11.3 33.1 12.1 23.7 17.7 14.6 5.7 55.9 13.4 20.1 26.0 39.4 34.8 28.8 10.8 13.9 32.7 16.2 17.2 5.8 21.8 57.1 10.9 9.7 8.3 9.6 5.8 25.1 29.1 18.9 14.8 32.8 18.6 49.1 61.1 49.9 51.9 46.8 48.9 68.7 50.9 51.2 60.7 62.2 45.7 51.4 8.1 61.4 38.3 41.4 72.6 83.3 17.6 20.9 11.4 19.8 18.6 15.5 22.2 17.2 17.5 20.6 80.4 82.4 123.2 165.8 73.0 19.3 280.9 234.4 97.7 73.9 137.9 15.7 632.1 432.7 146.8 45.4 83.1 264.9 46.7 80.0 307.0 84.6 125.8 115.7 460.6 245.2 35.0 181.6 92.7 111.3 42.2 121.1 102.2 138.3 289.5 227.3 54.7 110.4 235.9 134.4 659.8 17.5 77.6 99.9 79.1 47.7 79.4 485.8 139.5 278.3 180.2 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164583-32168281 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 1: 6.0;Alveolar cells type 2: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.2;Hep G2: 3.6;NB-4: 3.0;SK-MEL-30: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" NA NA Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 4.5 6.3 7.3 2.6 7.6 4.5 5.0 6.3 9.4 7.1 6.7 8.4 8.7 4.7 6.4 5.5 4.3 4.8 8.4 4.8 8.2 4.4 4.3 1.8 4.3 2.0 25.7 3.9 14.4 2.9 1.3 2.9 9.2 14.1 6.0 2.7 14.7 3.9 5.3 3.8 12.9 5.8 3.0 11.9 3.5 3.9 2.3 7.0 0.2 3.1 8.3 2.0 5.2 6.8 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.3 1.3 3.2 0.4 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 1.2 0.0 0.0 2.0 1.3 0.4 0.0 0.0 1.9 0.0 1.0 3.6 1.1 0.0 0.7 0.0 0.3 0.3 0.0 0.1 0.7 2.2 0.3 0.0 0.0 1.7 1.0 3.0 0.0 0.3 0.0 1.1 0.1 0.0 0.2 0.6 0.5 1.2 0.0 0.1 3.7 0.0 1.4 2.2 0.0 0.8 1.7 0.0 0.1 0.0 0.1 0.1 0.1 1.1 1.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.3 7.6 6.3 9.4 8.2 4.4 25.7 3.9 14.1 7.0 6.0 5.5 0.0 0.6 1.3 1.4 0.1 0.0 2.7 2.3 1.8 2.0 0.7 0.0 0.2 0.1 1.0 0.0 0.0 0.2 0.3 0.8 0.6 0.0 0.0 0.2 0.0 0.0 2.5 0.3 0.0 3.4 0.0 0.0 0.0 1.0 1.1 0.2 0.0 1.1 0.0 1.1 0.0 1.2 0.4 0.4 1.9 0.7 0.0 1.2 0.4 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 37.1;liver: 91.2" "Group enriched" "Detected in many" 7 "Hepatocytes: 227.5;Proximal tubular cells: 124.0" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 16.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 4.1 1.2 1.2 1.7 1.4 0.1 1.5 0.5 1.2 1.7 6.4 0.8 0.4 5.2 1.0 2.0 2.9 0.8 3.0 3.2 1.2 0.9 37.1 91.2 1.9 1.0 1.7 0.7 0.8 2.5 2.7 0.9 1.3 2.1 1.7 2.6 8.3 2.7 0.4 0.7 1.1 9.9 1.0 1.4 1.7 2.4 0.9 0.9 1.4 2.1 1.7 1.2 1.8 1.0 1.5 6.0 0.2 2.2 2.7 2.7 1.1 8.3 3.5 1.0 0.0 5.3 4.5 1.1 4.0 1.2 2.6 3.0 15.2 5.3 0.0 15.9 4.0 1.0 4.1 0.0 3.3 5.5 11.1 3.7 5.9 0.9 15.4 3.5 0.7 0.1 6.4 4.3 2.7 2.4 3.6 3.8 0.0 3.8 4.3 5.0 4.3 0.1 3.5 2.1 3.0 4.4 0.0 7.1 0.3 11.0 4.7 3.2 4.6 7.8 4.6 7.3 9.1 16.8 6.9 1.8 1.7 2.6 1.3 0.3 1.2 3.8 0.3 0.6 2.6 2.8 0.2 2.2 0.0 1.6 2.1 1.0 1.5 1.1 2.4 6.0 0.2 1.6 2.7 0.1 2.7 2.0 2.4 1.4 1.1 1.2 1.4 0.5 1.2 1.2 0.9 1.7 0.7 2.1 0.9 14.9 7.5 13.7 1.5 1.3 0.2 17.9 25.5 4.0 4.5 19.2 3.9 7.2 16.6 2.0 0.1 2.8 13.8 0.0 5.9 2.1 1.5 1.8 0.0 227.5 3.7 0.0 7.5 12.3 12.4 0.0 0.6 1.3 3.3 15.4 11.6 1.7 3.3 8.6 0.4 124.0 0.9 0.0 2.0 3.9 4.1 0.4 1.1 3.2 10.6 1.6 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022244-6059230 "Enzymes, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Cytotrophoblasts: 180.9;Syncytiotrophoblasts: 310.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: AB_2684583" "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 21.0 38.2 31.7 25.4 32.7 62.8 26.9 23.9 41.1 22.8 34.5 31.0 20.8 26.5 22.6 28.6 28.4 23.4 21.5 40.0 29.9 30.0 32.0 46.3 22.1 23.3 33.3 30.3 23.0 32.4 61.9 25.4 43.9 33.4 26.4 34.9 23.4 46.4 26.3 31.6 28.9 29.9 17.8 35.6 25.4 34.7 16.3 22.6 37.1 29.0 17.4 29.6 22.4 20.1 11.7 7.5 17.4 7.4 10.4 10.6 4.8 41.8 26.4 21.2 32.2 20.3 18.4 27.9 21.6 19.7 19.3 24.5 24.2 28.3 32.8 23.7 23.7 34.7 29.6 27.5 19.7 24.9 20.3 42.2 33.8 28.7 36.4 16.7 28.7 30.9 14.7 24.9 18.2 19.7 20.4 20.5 25.9 54.0 31.7 18.1 41.9 15.7 36.7 26.6 24.4 29.8 34.7 22.3 38.5 24.6 20.5 26.4 47.5 41.5 55.5 18.4 30.9 41.8 35.2 19.6 11.1 41.5 19.5 22.9 32.3 32.2 33.5 22.4 37.9 32.1 10.6 7.4 17.4 9.5 5.9 6.4 11.7 7.4 10.6 7.5 7.7 8.6 7.7 4.1 10.4 6.5 6.6 8.8 4.8 31.7 32.7 23.9 41.1 29.9 30.0 33.3 30.3 33.4 22.6 35.7 43.2 44.9 27.9 21.2 28.0 44.8 43.3 34.8 29.6 41.8 15.7 180.9 56.3 48.3 6.9 22.4 43.3 116.8 39.3 64.2 22.2 37.8 19.7 55.5 47.3 30.2 37.0 20.3 29.0 11.9 31.9 31.4 23.6 59.5 60.3 40.2 46.9 35.1 35.3 51.5 23.0 12.9 17.0 32.5 42.3 19.6 310.3 35.0 47.0 25.5 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157065 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol NA NA Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: AB_2685144" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 25.5 14.2 15.9 16.3 15.5 36.4 13.9 16.4 19.0 14.7 13.7 9.9 9.3 14.5 17.2 21.5 12.1 12.8 15.4 10.7 13.7 19.2 12.2 11.5 13.7 10.7 14.3 15.0 18.7 11.7 19.2 21.1 18.2 17.3 15.0 12.8 10.2 23.0 17.8 7.1 6.7 15.2 16.2 14.0 15.5 14.3 5.1 12.8 14.1 13.6 8.1 10.6 14.8 15.5 8.8 6.9 27.6 10.8 8.6 9.9 3.3 23.3 12.0 7.4 9.3 8.1 11.2 14.6 12.3 17.7 39.0 37.6 13.7 13.9 12.5 16.1 13.5 46.4 13.9 12.7 12.5 17.5 27.4 6.7 13.7 9.1 8.9 8.0 13.0 0.1 9.1 4.9 15.6 11.3 6.8 9.7 5.5 9.5 12.6 8.8 10.4 16.7 6.7 7.7 3.9 8.6 16.9 18.1 6.2 7.3 9.0 8.3 8.8 15.1 11.0 23.7 6.5 5.6 3.7 12.5 15.8 16.8 6.8 19.8 9.3 15.3 0.2 7.6 8.9 13.8 17.1 8.2 11.1 8.9 10.6 9.0 8.8 7.5 8.1 6.9 7.0 6.1 7.5 27.6 8.6 10.8 4.7 9.9 3.3 15.9 15.5 16.4 19.0 13.7 19.2 14.3 15.0 17.3 12.8 62.5 27.7 15.7 36.6 17.3 37.2 25.3 33.1 53.5 58.0 21.0 13.7 40.9 18.3 31.1 1.7 56.2 26.2 0.0 42.4 72.4 35.3 31.0 39.4 15.8 34.3 44.5 14.5 29.4 21.6 2.1 52.9 24.7 20.3 23.4 22.2 48.9 41.0 24.6 79.2 28.5 24.1 38.8 34.2 2.6 3.4 8.8 34.1 30.2 26.2 36.3 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627576 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Melanocytes: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 38.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved NA NA "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 12.7 10.3 7.2 12.3 7.6 18.6 10.7 8.8 6.6 15.8 10.7 6.1 20.9 7.3 9.6 12.4 9.5 8.9 8.5 11.1 5.7 5.5 11.5 15.9 10.4 9.3 7.9 5.0 8.8 36.7 18.5 18.4 14.4 8.3 11.4 12.6 7.3 28.0 20.9 12.7 8.9 10.8 7.0 7.5 11.1 19.0 4.6 7.3 8.7 15.7 6.3 17.3 21.5 19.2 6.6 2.6 1.5 0.7 1.6 2.4 0.6 4.9 3.3 7.2 4.7 13.3 9.3 11.5 7.1 9.2 5.1 7.5 7.4 3.6 38.2 4.3 4.9 7.9 4.5 5.2 4.0 7.5 13.4 3.4 4.1 3.3 7.5 8.3 5.0 9.7 3.5 6.4 4.7 10.2 7.6 5.5 4.5 2.4 13.7 3.9 5.6 4.7 4.0 5.3 9.3 3.8 18.5 10.0 6.8 6.3 9.4 5.6 7.7 4.2 10.9 7.2 9.1 4.0 3.0 4.3 4.4 4.7 9.9 4.4 25.7 12.9 27.0 6.2 4.6 5.9 1.1 0.7 1.5 1.7 0.6 1.9 4.7 1.7 2.4 0.9 6.6 1.5 1.1 0.2 1.6 0.2 2.6 1.4 0.6 7.2 7.6 8.8 6.6 5.7 5.5 7.9 5.0 8.3 7.3 8.9 6.9 11.2 8.5 18.0 6.0 4.8 17.8 4.0 1.2 12.2 7.9 3.7 0.0 3.3 0.1 7.7 8.6 0.0 5.5 5.9 13.0 14.2 1.1 11.3 4.1 1.6 13.1 9.8 5.7 0.4 6.9 6.4 30.4 1.0 26.4 2.9 8.4 8.5 5.3 2.6 1.8 0.0 10.3 2.6 3.4 15.9 5.6 7.5 5.1 12.1 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934146-40035591 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 32.9" "Group enriched" "Detected in all" 4 "dendritic cells: 32.9;monocytes: 9.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol NA NA Cytosol "HPA011811: AB_2668543" "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.7 16.5 20.2 19.4 27.3 20.2 36.0 22.4 27.3 16.8 16.3 13.6 17.1 12.2 35.7 17.9 17.8 18.1 19.4 18.2 19.5 20.5 15.4 22.7 22.5 16.6 18.6 14.2 20.1 21.5 20.3 34.7 20.5 17.6 22.0 14.6 17.9 16.7 20.3 20.4 20.7 12.2 24.3 14.6 16.1 16.4 11.5 15.1 17.7 24.1 10.6 15.9 27.0 14.4 5.0 32.9 4.2 9.3 3.8 4.5 2.4 14.0 6.8 12.1 18.2 19.9 33.6 11.5 19.8 22.8 16.3 16.1 9.6 6.1 7.5 10.4 26.9 21.8 15.0 16.1 24.0 22.7 35.3 8.1 15.9 12.5 11.6 17.1 9.6 11.0 26.5 16.5 15.5 27.9 23.0 22.6 15.8 11.7 7.1 32.0 4.7 8.0 13.2 7.4 12.5 15.1 9.7 16.8 12.3 20.2 9.6 6.3 9.7 14.2 8.6 12.3 12.3 12.1 16.6 24.0 21.7 16.5 10.8 12.8 9.8 17.7 2.3 15.2 13.2 30.3 4.2 5.8 4.0 3.6 6.7 3.1 3.5 4.0 4.1 8.4 5.0 4.5 4.2 1.7 3.8 9.3 32.9 2.7 2.4 20.2 27.3 22.4 27.3 19.5 20.5 18.6 14.2 17.6 15.1 14.9 23.6 17.2 22.6 10.6 28.5 28.8 22.9 13.4 26.1 15.7 11.8 29.7 11.6 22.9 1.0 27.0 7.3 0.0 22.0 29.4 26.2 25.6 23.1 20.8 27.4 27.0 13.8 23.4 28.6 2.4 39.1 46.9 30.4 32.5 20.8 31.3 33.9 10.5 37.4 15.1 22.8 45.3 18.6 9.8 29.6 12.7 12.7 15.8 27.6 17.2 EIF4EBP3 4E-BP3 ENSG00000243056 "Eukaryotic translation initiation factor 4E binding protein 3" O60516 5 140547666-140549578 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Exocrine glandular cells: 25.4;Paneth cells: 17.5;Undifferentiated cells: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 15.3;HSkMC: 14.3;JURKAT: 24.6;Karpas-707: 16.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045537 Uncertain NA NA "HPA045537: AB_10965796" "unprognostic (7.29e-2)" "unprognostic (4.20e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-1)" "unprognostic (6.64e-2)" "unprognostic (4.84e-3)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-1)" "unprognostic (8.36e-2)" "unprognostic (4.87e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.82e-2)" "unprognostic (3.75e-1)" 19.3 23.9 6.8 8.0 11.1 7.4 25.5 3.1 7.9 11.0 34.9 9.7 16.9 8.8 11.2 14.0 17.2 26.5 13.6 27.9 6.9 6.0 18.5 32.2 16.0 18.4 13.7 10.4 15.6 34.7 1.2 6.2 4.9 17.5 14.5 12.4 18.0 34.0 27.5 78.6 17.5 16.3 16.7 16.7 11.1 19.4 21.8 8.0 7.2 18.3 24.6 10.7 16.9 9.9 14.6 42.2 8.0 17.7 7.9 16.3 8.4 0.2 1.0 0.9 1.3 11.2 11.8 2.0 0.9 0.2 0.5 1.0 2.0 0.8 0.5 5.2 2.1 0.7 0.7 0.4 1.0 0.6 1.7 3.3 0.1 1.9 3.6 15.3 5.7 2.9 14.3 1.4 0.9 0.7 2.7 1.6 24.6 0.3 16.9 0.6 0.0 4.4 10.5 1.3 3.0 3.6 4.6 0.7 0.1 1.7 2.1 5.4 0.7 1.6 13.6 4.4 1.3 1.8 6.8 1.3 4.7 0.9 3.0 0.6 1.5 1.2 0.5 3.2 11.4 1.2 2.4 16.1 0.5 4.3 17.7 5.3 14.2 7.9 3.9 13.5 14.6 16.3 12.9 8.0 7.9 12.7 42.2 6.1 8.4 6.8 11.1 3.1 7.9 6.9 6.0 13.7 10.4 17.5 8.0 0.0 10.7 2.2 0.5 0.2 0.0 0.3 5.1 13.4 7.9 0.0 0.0 0.7 3.3 6.8 1.0 0.4 15.4 0.0 25.4 0.7 0.6 0.5 11.5 7.6 2.2 0.0 8.2 1.8 4.7 1.0 1.7 2.1 0.0 10.0 16.6 0.0 17.2 17.5 0.0 4.2 0.0 0.0 0.1 0.9 0.5 0.5 0.8 0.0 18.1 0.3 ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Enzymes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Enhanced Cytosol NA NA Cytosol "HPA025297: , HPA025812: AB_10601369" "unprognostic (1.29e-2)" "unprognostic (1.26e-2)" "prognostic favorable (9.25e-4)" "unprognostic (3.49e-3)" "unprognostic (5.73e-2)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.07e-2)" "unprognostic (7.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.89e-1)" "unprognostic (3.46e-2)" "prognostic favorable (1.31e-5)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" 14.8 15.3 18.7 11.5 23.4 6.7 19.4 20.0 27.4 33.4 14.8 21.8 35.2 10.8 27.3 14.4 12.8 18.6 17.5 16.0 17.7 19.0 19.1 22.8 13.6 15.4 17.6 13.6 18.9 12.6 14.3 17.4 12.7 23.3 15.9 18.0 13.9 11.1 36.1 28.8 13.4 12.3 16.0 15.8 16.1 12.1 15.0 15.5 16.0 19.9 13.8 20.3 14.7 12.0 16.2 12.2 11.6 18.2 15.8 20.8 11.0 14.5 15.2 11.6 11.1 17.2 15.1 8.3 7.5 13.6 17.7 15.8 12.6 6.2 27.4 11.8 14.4 15.7 9.9 12.8 17.8 20.9 4.9 5.3 18.4 10.1 20.9 15.4 9.9 13.7 15.9 27.6 12.1 18.7 12.8 16.5 21.3 20.7 17.0 18.0 9.0 21.1 16.9 13.1 14.0 5.3 16.0 11.3 10.5 17.6 12.0 7.0 12.2 8.5 7.3 14.3 11.1 13.9 11.5 11.6 12.1 15.9 12.6 10.8 7.2 11.5 21.0 12.0 11.2 12.3 11.6 10.1 8.2 19.4 14.4 20.8 12.5 16.6 18.3 11.8 16.2 15.0 17.0 2.8 15.8 18.2 12.2 15.6 11.0 18.7 23.4 20.0 27.4 17.7 19.0 17.6 13.6 23.3 15.5 3.0 10.1 10.4 6.7 2.4 6.7 14.6 7.6 13.4 12.5 7.0 21.6 12.5 6.6 10.5 5.9 8.7 7.7 0.0 8.6 12.1 6.4 6.2 8.1 14.7 13.2 14.3 1.2 9.8 11.5 2.7 7.8 7.2 1.7 7.2 8.1 8.7 8.4 8.6 9.6 11.1 11.1 0.0 6.6 11.4 16.1 2.0 8.7 11.5 9.9 5.1 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41091786-41180079 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 16.8 14.8 19.1 13.9 15.5 45.3 14.5 33.0 20.6 14.8 16.8 15.6 18.9 11.1 18.1 11.6 16.8 15.7 16.5 10.7 16.6 8.3 11.5 12.2 14.1 12.9 16.9 12.7 20.2 15.7 26.4 14.5 27.7 13.8 13.2 12.2 12.3 15.3 17.9 19.5 18.2 17.4 13.8 12.7 15.9 14.7 20.6 18.6 29.3 16.9 10.9 14.1 18.7 22.5 4.3 4.4 9.8 3.9 5.7 3.9 2.3 15.7 11.3 19.2 11.9 12.2 13.2 17.2 7.6 11.0 11.4 11.0 14.4 5.8 16.4 6.7 15.0 10.5 12.7 27.7 10.4 12.7 15.9 18.4 12.3 13.0 11.2 13.9 29.2 13.9 12.9 10.9 16.5 13.8 10.0 12.6 9.5 13.0 22.6 9.0 5.8 8.4 9.1 13.8 19.8 7.9 17.3 9.0 10.2 10.8 20.9 6.1 6.5 26.9 13.7 13.1 16.7 9.7 17.0 16.3 11.4 13.8 8.1 10.8 15.5 7.3 25.6 8.4 9.0 10.8 5.0 3.2 3.0 3.7 3.9 3.2 4.3 3.6 3.9 4.4 2.9 3.1 2.6 9.8 5.7 2.1 3.0 2.6 2.3 19.1 15.5 33.0 20.6 16.6 8.3 16.9 12.7 13.8 18.6 62.5 45.1 44.7 19.0 21.9 43.6 25.4 53.5 29.4 18.2 24.4 33.4 15.3 3.3 13.2 12.6 27.2 22.2 46.7 16.0 15.4 23.4 24.1 24.3 24.1 15.9 23.8 23.7 34.4 59.8 3.4 26.7 31.6 8.5 20.8 23.1 31.8 20.2 26.6 28.7 9.2 31.1 25.8 15.6 20.6 29.9 22.6 25.3 26.6 20.3 30.6 EPM2A "LD, LDE" ENSG00000112425 "EPM2A, laforin glucan phosphatase" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation, Epilepsy, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 60.9" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 23.5;Early spermatids: 28.2;Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 5.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 20.3" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm NA NA Nucleoplasm "HPA053643: AB_2797247, HPA055468: AB_2797252" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.4 6.0 8.8 1.9 9.0 2.2 3.6 4.0 8.9 3.9 11.1 8.6 2.5 3.4 4.8 4.8 8.9 4.3 3.9 19.4 9.6 8.7 8.0 5.7 3.5 3.4 11.9 5.5 5.9 2.9 5.5 3.3 2.0 9.6 6.2 3.4 5.6 3.1 9.2 60.9 2.4 3.3 13.9 13.6 2.5 4.6 3.3 7.1 3.7 4.2 15.7 2.9 10.4 6.0 1.4 1.0 0.3 1.4 5.4 2.4 1.0 1.1 1.7 3.3 6.3 8.2 2.5 1.4 3.0 3.5 2.8 3.4 1.5 1.7 20.3 2.5 3.5 3.4 1.8 1.2 1.3 2.5 7.9 1.7 3.3 2.4 2.5 5.0 11.3 2.0 2.1 6.8 1.7 0.6 3.7 2.0 4.8 1.4 5.2 3.5 2.6 7.5 2.4 3.4 3.0 1.7 4.3 3.0 5.9 2.5 1.7 6.1 6.1 5.3 3.2 7.0 3.1 1.8 6.5 4.3 2.8 1.4 2.6 2.3 3.8 3.8 8.2 2.4 2.7 4.4 0.0 0.1 0.1 0.4 1.4 1.1 1.3 1.1 0.9 1.0 1.4 1.2 2.4 0.3 5.4 0.3 0.9 0.2 1.0 8.8 9.0 4.0 8.9 9.6 8.7 11.9 5.5 9.6 7.1 6.0 1.0 3.2 0.8 0.8 7.9 23.5 5.1 2.7 3.4 1.8 5.9 0.7 10.0 0.9 28.2 1.5 0.3 0.0 2.0 0.6 1.2 1.3 2.3 5.8 2.0 28.6 1.2 1.3 1.5 14.1 2.8 3.1 6.8 0.0 1.5 7.5 1.1 1.1 2.1 6.3 6.7 0.0 2.0 1.6 1.3 0.4 0.3 0.0 1.0 0.3 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039142-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Intestinal endocrine cells: 76.4;Melanocytes: 70.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9;MAIT T-cell: 12.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 41.3;RPMI-8226: 18.5;U-266/70: 39.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB009495, HPA027730" Supported NA Yes "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 5.5 24.9 2.2 10.6 1.6 8.0 7.7 2.3 1.8 15.8 10.0 3.5 36.1 5.1 11.9 15.0 7.4 7.9 10.6 4.1 1.9 1.7 6.4 21.5 12.3 12.6 2.1 1.6 14.7 44.1 2.9 32.8 10.1 1.8 6.6 3.9 5.0 23.2 34.9 4.2 6.6 11.5 4.1 2.2 9.9 8.8 2.8 1.6 11.6 7.5 5.9 16.7 10.0 7.7 0.1 5.7 12.9 0.7 3.0 12.2 1.0 2.2 1.8 0.9 2.4 2.2 1.8 4.5 1.9 4.3 1.3 1.2 1.2 1.2 2.9 1.3 1.4 2.1 1.5 1.2 1.9 3.3 0.8 1.1 2.6 0.9 1.8 13.9 1.2 0.9 2.1 5.3 3.7 11.8 1.9 2.5 2.8 1.8 41.3 1.2 1.5 1.8 0.5 0.4 2.1 1.6 2.0 2.0 18.5 1.1 3.0 3.2 2.0 1.8 3.1 4.5 1.8 1.7 2.7 2.4 1.1 2.7 2.6 1.2 39.0 10.2 2.2 2.1 1.4 1.9 12.9 0.7 0.2 4.6 0.4 12.2 0.1 3.0 3.2 0.3 0.1 0.7 1.3 3.3 3.0 0.2 5.7 0.7 1.0 2.2 1.6 2.3 1.8 1.9 1.7 2.1 1.6 1.8 1.6 0.0 42.2 9.0 42.2 19.6 3.2 5.6 15.3 6.7 7.9 12.2 5.9 6.5 1.7 9.4 1.8 10.8 7.1 0.0 24.0 6.6 16.0 38.4 8.1 21.3 7.7 3.2 76.4 14.1 12.1 1.1 4.4 18.6 70.9 8.2 7.8 4.0 16.0 7.6 5.6 3.7 26.0 0.0 15.1 3.9 4.1 39.4 45.9 42.7 7.6 52.1 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690326-23713500 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.5;stomach 1: 30.0" "Cell type enhanced" "Detected in some" 20 "Cholangiocytes: 28.1;Enterocytes: 26.1;Mucus-secreting cells: 126.1;Paneth cells: 28.8;Undifferentiated cells: 53.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "OE19: 30.5" "Region enhanced" "Detected in single" "hypothalamus: 0.7" "Not detected" "Not detected" HPA076875 Approved "Intracellular and membrane" NA NA "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.3 0.1 8.1 0.2 0.0 0.1 0.1 0.2 11.4 17.3 0.2 0.1 7.0 1.1 0.1 0.9 0.1 64.5 0.1 0.1 0.0 0.2 0.1 1.0 0.5 0.1 0.1 0.1 0.5 0.0 0.8 0.1 0.1 2.6 12.6 0.2 14.0 0.1 0.1 0.1 11.8 0.9 0.1 0.1 30.0 0.1 0.1 0.2 0.1 2.2 7.6 6.3 3.9 0.9 0.6 3.6 0.4 1.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 30.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.4 0.5 0.3 0.3 0.2 0.3 0.3 0.3 0.1 0.9 0.3 0.4 2.1 1.5 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 1.0 0.0 0.0 0.4 28.1 4.0 6.8 0.0 0.0 0.2 0.0 0.6 0.1 0.0 26.1 0.0 1.8 0.0 0.0 1.0 4.6 0.0 0.1 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 126.1 0.0 19.2 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 53.3 10.4 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144085-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 110.1" "Cell type enriched" "Detected in many" 6 "Hofbauer cells: 646.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 27.6;myeloid DC: 33.7" "Group enriched" "Detected in many" 5 "dendritic cells: 33.7;monocytes: 27.6" "Cell line enhanced" "Detected in some" "AF22: 15.7;LHCN-M2: 5.8;RH-30: 29.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 56.6 19.4 2.2 11.4 6.5 3.1 57.9 2.2 1.8 13.3 21.8 2.6 2.5 2.2 4.7 35.6 13.4 16.8 12.6 55.4 2.0 2.2 17.5 1.3 14.5 52.7 5.8 1.4 10.2 8.9 5.3 9.3 110.1 7.5 16.4 15.1 11.6 11.5 3.3 18.5 10.4 10.6 20.1 5.0 5.1 11.5 16.7 2.5 2.7 22.4 8.3 6.1 23.7 6.5 0.0 33.7 6.6 27.6 0.0 0.1 63.5 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 29.5 0.5 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 27.6 0.2 0.1 4.9 0.1 0.0 0.0 0.0 33.7 0.0 0.0 0.0 6.6 0.0 0.1 2.4 0.0 63.5 2.2 6.5 2.2 1.8 2.0 2.2 5.8 1.4 7.5 2.5 0.0 3.4 0.8 0.0 16.7 0.0 7.5 10.2 4.0 0.0 0.0 0.0 4.0 0.0 0.0 3.8 4.7 0.0 0.0 0.0 3.4 16.5 0.0 1.1 0.8 646.4 0.0 0.0 4.3 113.2 4.2 4.0 57.6 18.6 1.0 0.0 0.7 0.1 0.0 0.7 3.1 4.1 58.2 9.2 1.4 1.0 13.2 8.5 0.0 0.0 0.0 F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197039191-197067267 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 95 "liver: 76.3" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 49.0" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.8;Hep G2: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" NA NA 3400000000 "HPA003827: AB_1078794, HPA052139: AB_2681744" "unprognostic (1.46e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 76.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489196 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 43.6;pituitary gland: 42.8" "Cell type enhanced" "Detected in many" 5 "Ciliated cells: 24.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "cerebellum: 18.0" "Cell type enhanced" "Detected in many" "T-reg: 13.6" "Lineage enriched" "Detected in many" 8 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.7;HDLM-2: 9.6;RPMI-8226: 19.4;U-266/70: 16.3;U-266/84: 8.3" NA NA "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favorable (2.66e-4)" "prognostic favorable (6.83e-5)" 1.0 1.4 1.0 6.8 1.5 0.0 6.7 18.0 1.0 3.5 3.9 0.2 3.8 2.6 1.4 4.7 5.5 5.8 2.4 0.6 1.2 2.3 9.7 20.1 3.5 5.7 1.1 0.5 1.9 43.6 12.7 42.8 1.4 1.8 9.3 3.6 3.8 9.1 5.3 0.3 10.0 6.4 0.6 1.1 2.3 4.1 0.6 0.3 8.5 15.3 2.7 11.0 3.0 3.6 1.8 1.0 0.3 0.0 0.7 13.6 1.5 2.5 0.2 0.0 0.1 0.1 0.1 2.4 0.0 0.0 0.0 0.0 1.8 10.7 0.1 3.1 0.0 0.0 0.4 0.8 1.9 0.0 9.6 5.2 0.3 2.5 0.7 0.0 1.1 0.0 0.0 3.2 0.0 0.0 0.1 0.0 1.0 1.2 4.8 0.0 1.0 0.5 0.0 1.8 2.2 0.0 0.0 1.8 19.4 6.3 3.4 1.8 0.1 0.1 3.0 0.0 4.6 3.0 0.0 0.0 0.0 0.2 0.0 0.1 16.3 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 4.7 1.8 7.7 3.2 0.0 0.6 7.5 0.9 0.3 0.7 0.0 1.0 13.6 1.5 1.0 1.5 18.0 1.0 1.2 2.3 1.1 0.5 1.8 0.3 3.0 5.6 0.0 11.2 2.4 3.1 0.3 2.5 24.1 6.8 5.2 17.7 4.4 8.3 8.3 0.0 0.0 3.9 0.0 12.2 2.1 0.5 10.4 0.0 9.0 0.6 1.6 12.7 0.6 0.0 0.0 0.6 0.0 3.3 1.0 5.6 1.2 11.6 3.4 0.4 4.5 12.2 0.0 0.1 0.0 0.0 5.8 4.7 2.5 4.7 9.0 FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128116 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 453.2;liver: 370.7" "Group enriched" "Detected in many" 5 "Enterocytes: 8164.5;Hepatocytes: 5503.1;Paneth cells: 3221.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 175.1;liver cancer: 437.4" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 23 "neutrophil: 2.3" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.3" "Group enriched" "Detected in some" 7 "CACO-2: 26.2;Hep G2: 83.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 32000000 "Nucleoplasm, Cytosol" "CAB002305: AB_563728, HPA028275: AB_10600909" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (5.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.35e-1)" "unprognostic (7.99e-2)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" 0.4 0.1 0.4 33.9 0.4 0.0 0.4 0.4 0.5 0.4 153.5 0.4 0.4 137.9 0.4 0.4 0.4 0.5 0.4 0.4 0.4 0.2 57.6 370.7 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 97.7 0.4 0.5 0.4 0.4 0.1 453.2 6.7 0.4 0.4 0.2 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 26.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 83.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.2 0.1 0.0 0.0 0.0 1.4 7.7 0.0 0.1 0.8 5.7 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.7 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.5 0.4 0.2 0.4 0.4 0.4 0.4 0.0 0.0 173.3 0.0 0.0 0.0 0.4 119.8 0.0 0.0 57.6 0.0 0.1 132.6 0.0 0.0 0.0 8164.5 140.2 0.0 0.1 0.0 0.3 133.2 5503.1 1.4 0.0 251.5 124.0 159.5 0.0 0.0 0.0 0.0 0.0 830.4 0.0 0.1 3221.0 0.0 668.9 0.0 0.0 0.0 0.0 0.1 0.0 1.1 51.0 1046.9 0.0 FAM20B "GXK1, KIAA0475" ENSG00000116199 "FAM20B, glycosaminoglycan xylosylkinase" O75063 1 179025804-179076562 "Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007409 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 280000 "Golgi apparatus" Nucleoplasm "HPA007409: AB_10601649" "unprognostic (7.58e-2)" "unprognostic (1.12e-1)" "unprognostic (4.97e-2)" "unprognostic (6.23e-3)" "unprognostic (3.29e-1)" "unprognostic (3.07e-1)" "unprognostic (4.76e-2)" "unprognostic (7.70e-3)" "unprognostic (7.85e-2)" "unprognostic (3.93e-2)" "unprognostic (5.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.76e-1)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" 18.2 21.3 17.7 12.8 20.9 8.8 26.0 16.1 26.4 15.8 20.8 10.8 13.3 8.7 18.5 14.7 17.5 14.7 17.3 32.9 17.1 17.2 16.2 14.8 14.6 9.1 16.1 19.9 19.0 10.1 22.5 16.9 15.2 15.2 15.6 13.4 14.5 9.9 18.8 19.0 11.4 10.6 25.9 13.6 10.5 14.4 6.8 9.4 7.3 16.5 7.7 9.4 17.6 28.7 4.9 3.6 2.3 2.3 4.4 4.1 1.5 17.9 16.5 12.8 13.5 22.9 24.2 14.2 15.0 17.2 10.6 9.5 8.2 18.0 9.3 19.8 26.4 8.7 13.2 13.0 11.0 15.6 11.8 8.8 29.7 15.6 10.4 11.4 19.6 18.8 14.0 12.1 14.4 11.2 16.2 13.0 13.1 33.0 13.7 16.9 10.0 8.5 7.1 16.8 20.3 3.5 10.5 13.5 12.4 8.9 20.4 17.1 42.1 15.8 18.0 15.3 19.0 15.5 14.4 13.7 16.9 14.9 23.2 20.2 11.2 20.4 8.2 16.8 9.6 16.7 2.3 2.0 0.6 3.8 1.7 4.1 4.2 2.4 3.5 2.2 4.9 3.5 3.2 1.9 4.4 2.3 3.6 2.7 1.5 17.7 20.9 16.1 26.4 17.1 17.2 16.1 19.9 15.2 9.4 6.0 10.7 11.2 8.9 13.9 12.3 31.9 17.8 8.1 7.9 17.4 23.6 8.0 3.3 8.2 4.2 11.2 4.1 0.0 11.0 5.7 12.4 14.8 16.2 12.2 6.9 36.5 13.8 10.4 8.9 2.5 16.4 6.9 15.1 10.0 7.6 7.8 11.0 0.0 20.1 5.4 20.2 12.9 20.3 12.9 15.8 11.3 6.3 6.9 6.6 23.8 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "Fanconi anemia complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 62.5" "Cell type enhanced" "Detected in many" 4 "Spermatocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favorable (7.80e-5)" 6.3 29.2 16.0 11.2 22.9 10.6 16.2 7.1 18.1 11.6 9.6 30.7 7.9 9.2 16.6 15.7 8.6 11.7 9.8 10.2 17.0 23.5 7.1 16.7 7.7 10.9 25.0 15.2 21.3 10.8 16.8 62.5 10.0 33.5 11.6 12.4 13.7 14.8 9.1 6.5 14.4 10.1 11.3 23.4 12.0 10.5 14.7 28.2 8.6 14.2 6.9 12.0 10.1 12.7 10.8 7.1 5.6 6.9 8.8 5.5 2.7 18.5 13.5 27.6 13.5 4.9 6.5 14.7 13.6 8.5 13.5 17.6 11.9 23.3 12.8 17.7 4.4 18.6 10.8 15.3 10.3 22.6 30.1 24.2 21.0 19.0 16.1 5.3 20.2 11.6 4.8 4.9 9.9 3.9 12.0 10.6 9.2 19.5 11.7 9.2 9.4 7.1 25.1 29.8 29.7 2.8 13.5 21.0 10.0 11.8 18.3 31.3 15.7 19.4 8.0 12.7 15.5 7.4 13.6 6.2 12.1 18.2 8.8 15.0 12.1 7.6 7.5 25.7 13.7 18.3 2.7 3.7 5.6 4.9 6.9 3.8 10.8 4.1 5.4 7.1 10.0 1.4 3.1 1.1 8.8 4.9 6.5 5.5 2.7 16.0 22.9 7.1 18.1 17.0 23.5 25.0 15.2 33.5 28.2 17.9 18.3 5.8 13.7 9.2 12.4 13.2 5.1 20.1 10.3 8.7 3.9 25.0 10.0 6.9 1.7 10.5 7.3 0.0 3.6 12.2 8.9 6.8 10.4 10.4 9.4 7.9 8.6 10.4 8.5 1.7 10.0 6.9 25.3 9.0 16.3 20.3 4.6 13.1 13.4 4.1 18.8 12.9 8.1 47.7 30.4 5.9 6.2 5.0 13.6 5.9 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Supported "Nuclear speckles,Mitochondria" NA NA Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favorable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 13.8 16.8 18.8 15.7 19.0 6.4 10.2 19.0 26.4 18.0 20.6 13.4 20.3 21.2 12.4 14.6 20.3 16.7 16.8 35.7 17.6 12.9 17.7 25.6 9.5 10.4 12.0 15.0 14.4 20.7 20.2 21.8 18.5 12.0 16.8 10.6 14.0 21.7 17.9 89.5 14.4 25.8 11.3 9.2 14.9 14.8 10.6 10.9 11.2 16.8 28.1 16.9 17.4 11.8 15.4 26.0 19.7 22.3 13.1 19.0 14.5 15.9 18.6 5.9 14.2 22.1 10.0 9.9 12.8 17.4 10.9 13.1 12.8 13.7 3.8 17.5 17.3 20.1 10.3 5.7 15.3 2.9 10.9 10.2 4.6 4.6 10.8 28.1 3.2 10.5 13.0 22.5 12.6 9.3 8.9 12.8 9.5 6.8 8.0 12.6 31.9 7.8 9.2 9.9 19.8 21.8 5.2 7.1 11.8 14.8 10.9 7.1 7.4 16.9 26.2 17.0 5.3 14.1 12.7 10.4 13.9 3.0 13.0 11.3 21.4 13.0 2.4 27.7 7.2 15.9 10.5 22.3 19.7 16.4 21.7 17.1 13.7 17.3 16.9 19.4 15.4 19.0 16.3 4.8 13.1 20.8 26.0 18.7 14.5 18.8 19.0 19.0 26.4 17.6 12.9 12.0 15.0 12.0 10.9 0.0 6.5 32.8 35.2 21.9 39.2 16.5 28.1 2.7 12.5 24.4 23.6 42.5 72.9 43.5 7.1 22.2 63.6 0.0 41.8 23.0 34.8 27.1 39.1 31.6 38.4 35.0 43.1 22.7 26.6 11.6 33.6 25.5 89.4 34.3 42.5 51.0 35.5 39.6 32.2 50.2 48.9 12.9 27.8 47.1 68.2 22.1 50.6 38.4 50.8 26.7 FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.4" "Cell type enhanced" "Detected in many" 13 "Alveolar cells type 2: 181.0;Cholangiocytes: 349.1;Hepatocytes: 122.9" "Cancer enhanced" "Detected in all" "liver cancer: 13.9" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 26.8;RH-30: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054971 Approved "Nucleoplasm,Nuclear bodies" NA NA 110000 "Nucleoplasm, Nuclear bodies" "HPA054971: " "unprognostic (4.15e-1)" "unprognostic (1.87e-1)" "unprognostic (2.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.47e-3)" "unprognostic (1.80e-2)" "unprognostic (4.09e-1)" "unprognostic (2.78e-1)" "unprognostic (2.92e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-3)" "unprognostic (7.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" 4.5 10.3 5.4 6.5 5.7 1.4 4.6 23.2 5.5 4.9 5.1 4.4 10.1 4.9 9.6 26.1 4.5 7.0 8.6 7.6 3.7 5.0 13.0 45.4 7.8 5.2 6.2 3.3 3.8 8.4 9.9 7.4 2.7 4.4 5.7 4.7 6.8 7.6 8.8 26.0 3.7 7.6 6.3 3.0 3.4 3.8 2.9 3.4 4.5 5.4 4.3 6.9 6.2 3.7 8.2 3.6 3.9 4.8 4.7 8.0 3.0 2.8 0.9 6.1 2.5 3.0 10.8 0.5 2.5 4.3 1.5 2.2 0.0 2.2 3.4 8.3 6.8 2.7 1.2 1.0 7.6 3.1 26.8 0.7 2.3 2.0 5.4 8.0 1.3 1.5 15.2 6.4 3.1 5.0 6.4 2.9 3.9 1.6 2.1 9.7 3.3 1.8 2.0 3.8 8.3 3.3 4.0 18.6 1.3 8.1 5.5 4.7 2.0 3.5 2.1 7.3 5.4 1.7 1.4 2.8 2.5 1.9 2.9 1.7 4.9 1.7 2.9 8.3 5.6 2.3 2.6 2.2 2.2 5.4 2.3 5.0 8.2 2.6 6.6 3.6 6.8 4.8 8.0 3.9 4.7 4.8 1.8 4.5 3.0 5.4 5.7 23.2 5.5 3.7 5.0 6.2 3.3 4.4 3.4 50.6 181.0 3.7 19.6 18.5 9.2 20.3 349.1 56.2 27.3 12.2 11.8 7.6 14.9 35.1 12.9 6.3 8.8 0.0 38.7 3.8 4.5 19.5 9.3 122.9 10.8 7.9 2.4 6.7 8.0 8.9 1.7 8.5 33.7 16.2 9.9 11.7 15.0 7.8 2.8 34.0 15.5 0.0 4.4 3.9 7.9 27.6 3.8 2.9 16.3 26.4 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad" P49789 3 59749310-61251459 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 138.8;Proximal tubular cells: 112.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "naive CD4 T-cell: 38.3" "Lineage enriched" "Detected in all" 14 "T-cells: 38.3" "Cell line enhanced" "Detected in many" "RPMI-8226: 12.1;U-266/70: 24.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 6.4 24.0 13.7 8.0 17.5 9.0 12.1 4.7 13.3 7.9 8.0 21.0 12.4 8.2 6.2 9.5 5.1 9.2 13.0 14.9 15.3 13.8 30.9 10.7 5.2 9.3 19.5 9.3 8.9 11.8 16.3 15.2 4.1 14.4 5.8 7.8 14.0 11.4 9.9 11.6 7.0 7.6 9.1 17.1 6.0 8.1 10.5 18.2 3.7 15.6 5.7 6.9 7.3 6.1 1.6 2.4 1.8 1.8 2.6 38.3 4.7 0.0 0.0 1.0 0.0 0.6 0.0 1.7 0.1 0.1 0.0 0.0 1.8 3.1 2.6 0.5 0.1 1.9 0.0 10.1 2.1 0.0 1.4 3.5 2.2 1.3 4.2 2.7 5.7 0.1 6.9 4.2 0.1 5.1 0.2 0.0 2.8 1.7 8.4 0.1 2.5 10.2 4.6 0.8 8.7 0.6 7.6 0.0 12.1 11.3 1.4 2.1 2.9 1.0 7.0 6.6 4.1 0.4 0.1 0.0 1.2 0.4 0.1 1.6 24.7 7.5 0.0 2.7 0.0 1.5 1.8 1.8 0.2 0.9 1.2 0.5 1.6 6.9 0.7 2.2 1.4 38.3 6.7 0.3 2.6 0.4 2.4 7.4 4.7 13.7 17.5 4.7 13.3 15.3 13.8 19.5 9.3 14.4 18.2 6.0 8.8 14.1 16.1 6.8 12.4 9.2 33.1 2.7 3.4 26.2 55.0 33.8 66.3 17.3 41.1 6.2 12.3 0.0 4.1 6.5 4.3 10.2 5.7 20.8 17.6 28.6 7.5 11.6 6.7 138.8 17.8 9.6 11.8 6.4 11.4 17.8 11.6 14.0 9.2 112.3 19.5 0.0 3.1 18.1 6.4 9.8 27.3 7.5 17.2 19.0 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 312.0;ovary: 80.7" "Cell type enhanced" "Detected in many" 9 "Basal glandular cells: 732.1;Extravillous trophoblasts: 503.8;Leydig cells: 525.0;Peritubular cells: 986.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 7.8;T-cells: 4.6" "Cell line enhanced" "Detected in many" "LHCN-M2: 79.9;RPTEC TERT1: 73.7" "Group enriched" "Detected in many" 4 "amygdala: 34.7;basal ganglia: 20.4;cerebral cortex: 51.8;hippocampal formation: 36.9;olfactory region: 18.3" "Low region specificity" "Detected in many" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 8.3 9.8 1.5 5.7 3.6 1.5 8.9 0.8 5.6 16.3 10.5 1.4 5.1 6.0 14.8 12.1 9.2 6.8 16.5 312.0 2.5 0.4 5.5 7.8 2.1 2.7 0.9 3.0 80.7 1.6 0.2 4.1 16.7 1.1 12.8 7.4 18.5 6.2 8.7 9.4 5.6 16.9 11.9 0.8 3.9 12.7 13.4 0.7 3.1 6.6 16.9 5.1 18.1 7.6 1.4 1.3 7.8 0.8 1.5 4.6 2.6 22.5 5.3 3.1 0.1 10.1 12.8 29.6 42.8 11.3 27.5 33.1 9.5 35.3 0.0 3.6 52.1 34.0 7.0 4.6 38.9 31.4 0.9 3.5 15.8 6.5 7.1 40.0 0.0 3.5 26.6 21.4 43.2 28.8 55.2 56.0 2.6 4.1 1.3 79.9 0.8 3.6 0.1 6.5 15.8 16.7 0.0 4.8 0.6 73.7 16.0 0.1 1.0 16.0 7.2 11.1 3.2 9.0 0.5 26.9 20.0 20.3 22.1 34.4 0.4 0.0 0.1 31.9 0.0 20.6 7.8 0.8 1.0 2.2 0.4 1.5 1.1 1.8 3.6 0.7 1.4 1.4 2.9 4.5 1.5 0.3 1.3 4.6 2.6 1.5 3.6 0.8 5.6 2.5 0.4 0.9 3.0 1.1 0.7 8.9 6.1 0.0 732.1 416.1 8.9 221.1 15.3 12.0 54.6 27.9 2.0 150.7 3.3 97.9 3.5 21.5 61.9 0.0 105.2 503.8 71.2 120.1 10.3 9.2 22.4 0.0 55.8 20.9 1.2 4.9 525.0 6.6 21.9 4.6 119.3 1.5 144.0 32.8 986.1 15.3 12.4 213.4 132.8 6.6 21.1 259.6 149.4 5.0 30.8 351.4 FKBP10 "FKBP6, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FK506 binding protein 10" Q96AY3 17 41812680-41823217 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Fibroblasts: 83.0;Leydig cells: 43.4;Peritubular cells: 42.1;Sertoli cells: 58.2;Smooth muscle cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "NK-cell: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 72.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 5500 Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 16.9 16.5 6.6 13.2 7.2 0.2 14.9 3.4 8.4 43.0 11.5 6.0 15.8 3.8 42.7 39.0 14.0 21.4 28.6 19.2 5.6 3.6 10.3 3.2 16.2 17.1 5.3 6.7 35.5 13.5 24.7 22.7 33.8 5.2 21.3 5.7 17.1 6.5 17.0 9.6 8.8 7.6 27.9 5.5 7.9 8.5 15.1 5.7 1.2 16.9 9.5 8.1 24.4 19.2 0.3 0.0 0.0 0.0 2.0 0.9 0.1 0.0 16.2 15.0 49.1 52.8 61.7 13.2 66.9 67.0 25.2 21.8 8.4 0.6 0.0 0.9 72.6 6.4 0.1 8.9 17.8 10.7 4.4 13.5 6.4 18.3 24.0 57.7 0.0 0.0 66.2 0.0 20.6 15.8 48.4 21.4 0.0 0.2 2.3 21.0 21.1 0.0 0.0 11.7 34.3 5.5 1.3 17.7 2.1 4.3 0.0 3.7 13.1 0.1 48.1 22.4 19.8 7.5 0.4 24.2 30.4 15.8 20.2 10.2 0.1 0.0 0.0 41.7 0.0 29.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 6.6 7.2 3.4 5.8 5.6 3.6 5.3 6.7 5.2 5.7 0.0 7.4 0.0 10.9 7.6 0.8 1.6 2.5 0.0 2.3 0.0 0.0 6.3 0.0 8.8 0.5 23.9 0.0 0.0 4.2 23.1 83.0 4.1 0.0 0.0 4.2 14.3 0.0 34.4 0.0 1.9 43.4 2.2 15.1 0.0 1.4 29.2 3.0 0.0 42.1 0.0 1.0 58.2 43.4 0.5 8.3 4.4 10.0 0.0 0.6 1.7 FKBP11 FKBP19 ENSG00000134285 "FK506 binding protein 11" Q9NYL4 12 48921518-48926474 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 175.6;salivary gland: 62.0" "Cell type enhanced" "Detected in all" 7 "Exocrine glandular cells: 145.3;Melanocytes: 258.1;T-cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "MAIT T-cell: 37.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 44.0;Karpas-707: 40.1;OE19: 56.1;RPMI-8226: 40.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 5.6 4.6 1.1 8.2 1.4 3.7 3.7 0.9 2.2 7.5 6.9 0.9 21.6 9.2 4.4 12.9 4.4 4.8 8.1 3.4 1.3 2.4 4.8 38.4 5.8 16.6 1.0 1.3 3.7 175.6 0.2 12.3 3.3 1.6 4.8 6.3 1.9 62.0 20.9 1.4 1.7 7.6 2.9 1.0 18.7 10.0 1.9 0.9 2.2 4.7 4.9 14.5 8.2 4.3 11.1 8.3 1.1 0.3 5.1 37.6 7.3 2.0 2.7 0.5 0.7 12.0 18.2 1.0 15.9 22.8 17.6 20.8 10.2 11.4 30.9 0.5 25.9 0.2 8.5 5.5 7.0 9.1 6.5 1.1 1.1 2.9 0.1 44.0 0.6 0.8 20.3 13.5 13.5 25.1 7.5 9.9 10.5 0.4 40.1 6.4 5.8 4.6 1.1 1.4 56.1 5.1 12.7 0.7 40.1 2.2 0.4 6.5 1.9 5.3 7.9 3.5 0.6 0.4 0.9 7.9 3.4 0.6 0.3 0.3 23.5 19.4 15.7 2.1 0.7 5.6 0.9 0.2 0.6 22.5 0.3 37.6 11.1 15.6 17.7 0.3 4.8 9.4 14.4 1.1 5.1 0.1 8.3 6.4 7.3 1.1 1.4 0.9 2.2 1.3 2.4 1.0 1.3 1.6 0.9 14.9 18.4 30.6 44.0 25.1 4.9 1.7 35.7 28.1 19.4 8.7 37.3 19.0 6.6 17.0 15.1 19.7 11.7 46.7 145.3 59.9 74.1 89.1 12.7 90.3 9.7 1.6 24.1 49.1 14.2 13.2 25.6 9.7 258.1 5.4 84.9 1.5 80.1 7.0 13.1 12.2 15.0 6.5 22.1 8.0 6.8 18.6 35.4 152.0 40.1 37.6 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FK506 binding protein 14" Q9NWM8 7 30010587-30026684 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 8.8 7.4 8.7 9.2 7.3 5.1 8.8 17.6 7.7 14.9 7.8 4.1 6.9 4.2 12.1 14.2 8.0 8.1 8.5 9.8 7.1 5.2 5.4 9.2 7.6 8.1 9.2 5.2 13.0 9.8 8.6 27.8 10.7 7.1 9.8 6.9 8.4 7.6 10.9 3.3 6.4 5.3 18.8 8.1 6.7 7.2 4.2 7.1 2.6 5.6 5.9 7.7 13.4 8.7 1.6 3.3 2.7 1.2 1.0 1.6 0.6 3.4 2.6 7.4 17.2 19.3 24.8 3.4 17.7 16.6 6.2 12.1 2.2 2.2 1.2 8.4 15.5 7.6 7.6 4.1 6.4 12.4 0.6 5.9 2.8 5.0 6.5 9.8 2.0 4.9 15.5 6.7 10.8 12.8 14.6 13.7 1.8 4.5 2.6 11.1 1.4 1.0 2.4 3.9 3.8 4.8 0.0 5.0 4.0 6.1 3.1 1.9 6.5 6.2 14.2 4.3 9.2 3.2 2.6 11.0 6.6 7.7 11.3 7.0 3.9 4.0 2.1 9.4 1.9 20.6 1.9 1.2 1.2 1.3 0.8 1.0 1.1 1.6 1.1 2.2 1.6 1.5 1.3 2.7 1.0 0.5 3.3 1.4 0.6 8.7 7.3 17.6 7.7 7.1 5.2 9.2 5.2 7.1 7.1 17.9 16.5 3.7 19.2 24.4 15.5 13.5 7.6 2.7 10.3 17.4 25.5 9.5 1.7 6.7 0.3 7.4 3.3 0.0 3.2 24.1 26.4 15.0 2.3 6.6 5.3 14.3 1.2 8.6 2.8 0.0 12.0 5.8 10.1 2.8 7.9 31.5 5.3 14.4 19.4 2.9 19.8 6.5 10.5 0.7 3.3 15.9 13.2 4.3 4.8 24.8 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FK506 binding protein 1A" P62942 20 1368978-1393172 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 63.6;granulocytes: 88.4;monocytes: 94.3" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 152.2;TIME: 176.4" "CAB004639, HPA051798" Uncertain NA NA 16000000 "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 106.0 42.4 67.3 55.0 114.8 44.4 63.5 15.8 55.8 33.2 39.7 22.1 33.8 32.7 45.5 45.9 42.7 33.8 32.0 36.4 51.7 30.6 41.9 41.7 59.2 84.1 26.0 36.5 41.7 57.7 20.6 21.7 65.0 22.5 34.4 49.4 21.4 30.8 40.6 38.9 31.5 37.1 56.0 23.3 68.0 33.0 21.1 28.4 47.4 62.2 39.7 48.3 48.1 37.0 13.3 63.6 88.4 94.3 14.5 18.6 84.3 71.4 19.8 15.8 22.8 53.5 67.2 20.8 45.4 30.8 36.4 33.8 19.8 27.8 29.3 14.6 42.3 52.9 32.9 20.4 83.1 47.9 8.4 22.1 30.0 9.3 37.6 32.9 34.8 16.7 39.0 26.5 33.7 34.8 42.5 152.2 33.0 27.4 15.1 42.8 8.9 34.0 48.0 33.9 25.3 38.8 29.2 27.6 35.4 47.0 18.1 26.3 19.9 22.4 45.3 75.2 22.1 17.7 29.7 176.4 135.4 22.7 28.8 33.5 7.5 16.3 30.6 23.3 35.4 29.9 23.9 79.4 88.4 11.5 94.3 10.2 12.8 13.9 13.2 63.6 13.3 14.8 14.2 77.9 14.5 90.3 31.6 18.6 84.3 67.3 114.8 15.8 55.8 51.7 30.6 26.0 36.5 22.5 28.4 80.4 70.6 192.2 178.9 233.8 16.6 52.9 173.3 66.9 58.0 164.0 0.0 249.8 202.2 393.2 31.1 486.6 196.8 23.3 297.3 496.2 197.8 189.6 142.9 99.4 651.5 33.4 317.5 445.0 487.0 41.0 185.2 363.6 229.5 390.5 244.5 40.1 382.3 768.7 153.1 245.7 11.0 135.8 189.1 153.9 133.6 261.7 193.6 124.6 263.1 202.2 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FK506 binding protein 1B" P68106 2 24049701-24063681 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1;intestine: 24.9" "Cell type enhanced" "Detected in many" 4 "Pancreatic endocrine cells: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 5.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 21.9;NTERA-2: 21.3;SH-SY5Y: 15.5;SuSa: 23.9;TIME: 18.6" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 2.9 5.9 25.0 2.8 30.7 1.9 5.9 15.7 23.1 5.1 7.2 1.6 7.4 24.9 3.6 4.2 4.5 4.5 7.1 3.4 31.1 14.0 4.4 4.6 9.0 2.2 13.0 19.7 4.6 4.9 6.4 2.8 5.6 7.9 5.1 4.6 2.4 3.3 9.2 1.1 3.6 6.7 4.0 5.2 1.8 13.3 1.6 4.4 0.6 5.0 1.1 3.2 7.1 3.5 1.5 2.2 4.4 0.8 0.3 5.4 1.1 0.1 0.9 8.5 0.0 5.4 2.1 3.0 2.8 2.9 1.2 1.8 0.5 1.0 0.0 2.1 5.0 7.7 3.3 12.5 9.8 0.8 1.4 8.0 2.9 0.1 21.9 2.0 0.0 7.0 2.0 2.3 2.9 0.6 7.3 7.9 3.3 0.7 0.0 2.8 0.0 0.9 0.0 21.3 0.7 1.5 1.5 0.7 0.0 0.9 0.5 2.1 15.5 0.1 0.0 2.7 23.9 0.5 1.0 18.6 0.0 2.6 0.1 0.6 0.5 0.2 0.0 3.1 0.0 0.6 1.3 0.8 4.4 0.3 0.7 0.0 0.3 0.6 0.5 2.2 1.5 0.0 0.2 0.1 0.3 0.0 0.4 5.4 1.1 25.0 30.7 15.7 23.1 31.1 14.0 13.0 19.7 7.9 4.4 0.0 5.0 0.0 11.5 8.1 1.2 0.4 28.1 1.4 0.0 7.0 0.0 4.5 11.6 24.5 0.4 9.3 9.3 0.0 33.8 22.1 7.8 15.8 1.1 9.8 6.2 1.6 9.1 11.1 3.4 1.8 2.6 9.4 27.0 19.8 7.9 12.1 37.4 28.1 3.9 4.1 2.5 25.8 11.2 1.4 3.0 6.5 4.3 0.0 3.4 14.5 FKBP2 "FKBP-13, PPIase" ENSG00000173486 "FK506 binding protein 2" P26885 11 64241003-64244132 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 119.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" No No 400000 "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 18.2 35.8 28.9 20.2 35.5 12.1 20.2 18.8 27.1 31.3 28.0 20.3 87.8 39.0 24.4 102.7 20.8 25.5 30.3 28.0 29.7 35.7 40.3 89.6 18.8 17.0 39.3 24.8 22.1 107.2 34.0 57.2 59.2 29.0 26.1 21.9 19.4 59.3 116.6 11.8 18.5 30.2 19.7 28.5 20.9 31.1 19.8 20.6 12.4 63.2 18.6 18.8 21.3 23.9 21.3 119.6 29.0 25.4 20.0 30.7 15.5 24.2 32.0 17.3 35.0 37.5 21.4 24.6 29.4 29.9 22.3 20.7 31.5 54.7 18.0 46.9 36.1 30.5 31.8 13.7 24.4 10.6 22.3 11.9 19.9 42.6 32.1 49.3 16.5 28.0 24.9 36.4 29.5 32.6 32.2 17.7 16.3 14.9 53.9 26.4 40.1 18.0 26.1 20.2 41.7 28.9 16.1 17.1 65.5 40.3 24.4 24.2 21.1 20.2 57.2 32.4 12.7 22.0 14.3 16.7 26.8 23.9 42.6 15.7 32.8 10.2 14.6 35.9 17.4 30.3 29.0 24.5 3.4 24.1 25.4 30.7 21.3 19.2 23.3 23.2 20.5 13.0 18.1 9.1 20.0 20.8 119.6 7.1 15.5 28.9 35.5 18.8 27.1 29.7 35.7 39.3 24.8 29.0 20.6 137.0 150.2 102.0 207.7 146.1 76.1 98.2 310.8 108.4 116.0 369.9 21.6 256.2 349.8 239.2 83.7 136.1 585.6 23.3 222.4 308.7 201.1 281.8 142.9 635.0 211.8 30.2 328.9 152.9 95.0 70.2 213.2 169.2 285.1 186.7 264.4 122.7 276.9 273.5 239.7 629.6 65.3 181.1 142.1 273.8 237.0 146.9 518.9 105.4 226.6 265.6 FKBP3 "FKBP-25, PPIase" ENSG00000100442 "FK506 binding protein 3" Q00688 14 45115600-45135319 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 980000 Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 11.7 13.2 28.1 10.2 40.7 9.8 15.5 25.1 32.1 12.0 14.6 11.4 8.3 13.2 9.9 20.4 14.6 8.8 9.1 31.3 26.0 24.4 16.5 20.5 8.0 14.6 23.2 23.8 9.9 10.9 15.0 17.1 14.0 22.9 17.9 15.2 6.6 10.7 12.2 113.3 11.3 13.9 12.8 19.6 9.9 10.6 13.5 22.4 12.7 12.4 24.2 16.5 12.7 9.3 19.5 27.5 13.5 17.4 15.4 19.4 13.0 37.3 41.6 60.6 31.9 27.0 29.4 23.9 23.0 26.4 36.3 40.1 36.3 32.1 19.9 24.3 25.9 20.6 31.1 45.0 29.6 51.9 28.7 26.8 16.4 32.3 46.9 26.6 28.2 17.7 27.7 30.9 21.1 19.7 33.6 47.3 31.7 23.6 15.1 43.1 45.6 45.3 37.9 30.7 41.9 39.5 43.6 44.7 24.2 58.1 43.2 37.0 14.5 36.8 22.9 35.2 47.7 53.6 21.2 30.4 27.8 48.1 14.5 17.6 25.4 45.1 31.0 16.8 19.5 25.9 11.6 14.6 13.5 13.0 17.2 15.7 19.5 17.5 17.6 21.8 13.6 16.8 18.8 2.3 15.4 17.4 27.5 19.4 13.0 28.1 40.7 25.1 32.1 26.0 24.4 23.2 23.8 22.9 22.4 38.7 36.9 49.1 82.5 42.5 68.8 177.9 45.9 77.6 69.4 89.0 9.8 264.9 213.9 116.4 165.9 49.2 61.3 0.0 64.1 95.4 67.9 74.9 51.0 84.7 113.7 38.1 53.9 39.3 36.8 297.6 74.8 68.0 65.8 155.9 63.2 57.4 80.6 52.6 91.9 168.1 44.8 103.5 53.3 145.7 112.4 41.9 138.0 47.9 83.1 70.8 FKBP4 "FKBP52, FKBP59" ENSG00000004478 "FK506 binding protein 4" Q02790 12 2794953-2805423 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "vagina: 209.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006148, CAB017441, HPA062857" Supported Enhanced Nucleoplasm,Cytosol NA NA 110000 Cytosol Nucleoplasm "CAB017441: AB_10618759, HPA006148: AB_1078875, HPA062857: AB_2684883" "unprognostic (1.46e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.12e-5)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-1)" "unprognostic (3.14e-1)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (2.22e-1)" 16.2 21.6 26.0 13.7 30.7 13.3 40.7 50.4 31.9 19.9 22.6 22.8 36.2 13.1 20.1 30.7 34.2 25.7 16.4 20.4 25.0 32.5 31.6 31.3 15.8 11.7 44.7 23.4 23.9 30.3 30.1 19.5 32.0 39.4 30.2 25.3 11.5 30.1 31.6 33.5 25.3 16.1 26.4 25.2 11.5 25.3 36.0 42.1 15.6 47.1 16.5 18.5 17.4 209.6 13.8 6.0 10.9 13.7 8.4 14.0 9.9 15.3 34.2 9.9 16.6 12.3 7.3 47.5 15.1 5.4 25.0 16.9 34.0 18.8 20.5 4.3 9.7 17.4 21.1 61.5 20.5 30.1 37.5 39.4 22.6 25.1 12.0 9.5 17.6 6.2 6.6 18.8 29.5 29.6 14.9 14.5 20.8 20.7 29.3 10.0 44.1 30.9 16.0 84.3 45.3 24.7 18.6 17.4 12.3 21.0 19.6 14.3 20.5 17.5 47.8 7.6 64.7 64.4 12.0 7.7 12.3 38.7 13.8 38.0 7.3 11.2 30.3 10.9 26.4 12.5 10.9 10.8 5.9 12.5 9.8 14.0 13.3 11.1 11.8 6.0 13.8 11.8 13.7 1.5 8.4 13.7 5.3 10.1 9.9 26.0 30.7 50.4 31.9 25.0 32.5 44.7 23.4 39.4 42.1 6.0 8.6 47.9 182.5 127.9 60.2 11.7 40.8 16.0 12.5 50.6 70.7 148.6 131.0 77.3 90.2 33.8 86.8 0.0 22.4 85.7 62.6 189.3 39.1 41.9 54.7 92.2 101.7 12.3 15.0 26.1 32.2 42.7 87.7 52.3 61.6 41.8 62.2 84.2 36.4 112.7 51.3 84.1 88.6 179.1 92.0 116.1 186.7 20.2 77.5 121.3 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FK506 binding protein 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 277.2" "Cell type enhanced" "Detected in many" 7 "Kupffer cells: 325.8;Peritubular cells: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 103.4;ASC TERT1: 64.4;HHSteC: 81.0;HSkMC: 97.8;hTCEpi: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 78.8 20.7 9.5 14.2 15.6 4.9 36.7 2.4 10.9 16.5 29.0 5.1 29.8 2.2 18.6 16.9 29.2 19.4 17.9 26.3 10.6 4.2 44.9 30.7 19.7 55.9 15.7 3.6 27.2 43.7 8.6 33.8 6.0 13.1 18.3 8.2 11.8 30.4 25.1 277.2 20.2 36.7 18.6 18.2 32.3 25.0 14.3 12.4 20.1 24.2 9.8 16.8 22.5 18.4 4.0 30.6 24.9 31.2 11.8 42.3 39.9 5.0 2.2 9.7 14.4 103.4 64.4 0.1 2.7 0.1 1.8 4.1 3.8 0.9 25.0 2.6 0.5 1.5 0.0 5.7 12.1 4.3 9.8 5.5 10.7 1.9 5.3 81.0 6.7 1.1 97.8 49.2 3.1 29.7 1.9 10.5 5.0 11.4 10.2 19.0 3.2 27.9 12.6 2.5 1.1 1.6 12.4 2.5 12.2 8.0 3.0 3.7 2.2 2.2 2.6 0.5 2.2 14.3 7.9 23.2 2.6 2.3 0.3 3.8 4.6 5.3 31.7 0.8 13.2 1.0 13.7 31.2 19.4 20.0 27.0 23.8 3.0 28.2 20.8 30.6 4.0 42.3 30.2 24.9 11.8 12.0 9.2 10.3 39.9 9.5 15.6 2.4 10.9 10.6 4.2 15.7 3.6 13.1 12.4 11.9 9.9 41.7 52.1 15.7 1.7 110.1 79.0 21.4 13.6 5.2 0.0 0.6 19.9 0.5 8.8 66.1 19.7 163.5 6.9 0.9 22.2 38.7 36.0 165.7 28.8 0.0 20.1 130.8 325.8 11.8 149.0 56.5 6.8 91.0 17.5 3.7 3.3 9.3 205.4 16.3 18.2 142.3 28.8 11.6 19.2 18.6 0.3 117.1 19.5 19.5 FKBP6 "FKBP36, PPIase" ENSG00000077800 "FK506 binding protein 6" O75344 7 73328164-73358637 "Disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 33.0" "Cell type enhanced" "Detected in some" 18 "Early spermatids: 62.1;Late spermatids: 61.4;Spermatocytes: 105.5;Spermatogonia: 35.0" "Cancer enriched" "Detected in single" 9 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;Karpas-707: 1.5;SiHa: 2.1;U-266/84: 1.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA061109 Enhanced NA NA "HPA061109: AB_2684430" "unprognostic (5.07e-2)" "unprognostic (3.34e-2)" "unprognostic (1.56e-1)" "unprognostic (1.91e-1)" "unprognostic (1.05e-1)" "unprognostic (3.98e-2)" "unprognostic (8.72e-3)" "unprognostic (4.34e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-1)" "unprognostic (4.29e-2)" "unprognostic (1.48e-1)" "unprognostic (6.20e-2)" "unprognostic (9.15e-2)" "unprognostic (2.47e-1)" "unprognostic (6.86e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 0.5 0.6 0.8 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.3 0.3 2.1 0.0 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.8 0.2 0.7 1.3 0.0 0.4 0.3 0.3 0.5 0.3 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.8 0.4 0.0 20.1 2.3 0.0 0.0 0.0 0.0 0.3 62.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 61.4 2.8 0.0 0.0 0.0 0.0 0.5 0.2 0.0 1.1 0.0 0.3 0.0 0.0 105.5 35.0 0.0 0.1 0.0 0.0 0.1 FKBP7 FKBP23 ENSG00000079150 "FK506 binding protein 7" Q9Y680 2 178463664-178478600 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 116.0;Fibroblasts: 67.2;Leydig cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 52.8;ASC TERT1: 32.8;HSkMC: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.6 4.6 1.5 4.3 4.1 0.7 11.1 3.5 2.3 20.5 6.9 1.0 10.0 1.8 21.4 21.9 8.4 12.4 12.8 12.1 1.5 1.5 5.5 7.4 6.8 5.2 4.0 1.8 34.6 4.3 1.5 11.1 8.2 2.9 19.5 4.2 7.1 4.9 9.7 4.4 4.0 3.9 19.9 3.9 3.0 5.3 8.3 2.2 2.2 8.7 8.0 2.3 15.5 9.9 2.8 5.8 0.2 1.6 1.2 2.8 0.8 0.0 0.6 6.1 9.0 52.8 32.8 0.5 10.9 18.1 2.0 6.4 0.1 0.6 1.7 2.4 19.9 1.8 0.1 2.3 0.9 3.5 1.4 1.3 1.7 2.5 1.7 8.1 1.1 1.3 22.0 0.5 8.0 1.1 14.7 6.5 2.1 0.8 1.1 8.4 0.1 1.9 1.9 1.2 1.1 0.9 2.5 10.7 2.3 2.7 0.2 3.2 10.6 2.3 0.0 1.8 4.5 0.1 2.1 6.0 3.7 2.3 4.3 1.0 2.1 2.2 0.8 6.8 2.7 8.0 0.0 1.1 0.1 2.3 1.6 2.8 2.8 2.0 1.6 5.8 1.7 2.2 2.4 0.2 1.2 0.0 4.5 2.2 0.8 1.5 4.1 3.5 2.3 1.5 1.5 4.0 1.8 2.9 2.2 6.0 2.6 2.2 6.7 6.3 4.6 12.6 2.5 2.7 3.4 7.0 0.0 6.2 1.7 9.1 116.0 18.6 0.1 0.0 7.4 18.5 67.2 3.6 13.9 9.8 5.3 4.8 1.2 13.5 4.3 22.0 59.2 4.8 16.9 1.8 4.8 3.7 4.0 0.0 45.6 3.5 3.3 6.5 39.2 3.7 5.5 5.1 4.2 5.0 2.6 3.4 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FK506 binding protein 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Late spermatids: 972.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 32.5;neutrophil: 31.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 44.3 38.1 75.9 27.5 82.1 82.5 26.5 43.4 113.7 35.2 31.9 41.2 34.6 31.1 31.4 27.2 48.7 39.3 34.5 43.4 69.6 62.1 28.9 42.7 34.3 31.1 55.3 54.3 56.1 60.4 28.8 42.2 36.6 51.2 36.5 12.9 31.9 73.1 46.1 56.7 35.1 31.6 34.6 46.3 36.7 31.9 49.5 26.9 32.1 38.8 24.2 30.7 36.3 45.8 4.3 4.3 32.5 6.9 3.1 6.6 9.1 36.9 26.5 20.8 39.5 21.5 33.8 52.2 29.9 31.9 22.9 31.8 25.1 50.5 21.2 48.7 36.7 15.4 20.1 12.8 41.7 6.5 25.8 60.9 19.8 34.6 30.2 37.0 19.6 43.6 44.1 40.2 20.6 13.1 44.1 23.5 41.3 41.4 50.5 19.9 61.6 35.6 58.7 42.5 33.2 38.5 37.4 17.3 72.4 30.8 24.2 23.1 42.1 21.0 17.3 37.3 16.5 20.4 57.2 27.4 28.7 26.2 55.9 22.7 38.6 22.2 24.6 64.8 31.5 25.4 6.3 5.6 32.5 6.0 5.8 5.5 4.1 6.1 6.6 4.3 4.3 4.7 5.3 31.0 3.1 6.9 4.3 6.0 9.1 75.9 82.1 43.4 113.7 69.6 62.1 55.3 54.3 51.2 26.9 8.9 1.4 107.1 128.1 84.6 57.2 2.0 71.4 2.7 5.7 96.0 13.7 219.4 210.5 151.9 314.6 76.6 289.8 233.6 111.8 173.9 174.8 132.3 54.0 55.9 208.7 93.8 197.7 79.8 159.9 972.7 188.7 127.3 192.3 254.3 108.6 104.6 130.6 224.5 155.6 222.1 41.3 97.0 149.9 203.6 97.7 103.1 261.7 163.0 127.0 126.6 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FK506 binding protein 9" O95302 7 32957404-33006931 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 58.4;fHDF/TERT166: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 35.4 21.1 9.7 12.5 13.6 0.9 43.7 4.5 16.3 33.6 18.3 9.3 16.8 8.8 31.3 30.9 23.7 24.1 28.8 44.4 9.7 11.9 18.2 10.1 30.6 17.5 10.8 9.7 25.9 26.0 12.9 16.0 35.2 13.2 23.7 21.2 30.4 16.0 25.6 17.1 28.0 13.4 37.0 12.8 10.7 17.4 16.3 6.4 2.9 18.9 19.4 11.1 23.7 23.6 0.4 1.4 7.4 4.1 0.3 0.1 0.9 7.1 13.6 5.3 21.9 50.4 58.4 7.1 38.7 40.3 12.8 20.4 5.9 17.0 0.0 15.8 71.8 20.5 14.0 7.8 18.9 14.7 0.0 2.3 1.2 14.6 5.8 21.0 0.0 2.1 37.9 11.5 11.4 11.1 30.5 16.1 0.0 2.7 1.4 26.0 6.9 0.0 3.6 1.1 14.3 7.2 0.0 14.3 0.0 14.3 2.4 5.0 12.1 22.1 11.3 13.7 14.1 7.9 3.5 21.5 21.0 20.2 13.0 8.8 4.6 8.9 0.0 20.5 0.0 41.7 1.5 4.1 0.9 0.1 2.6 0.1 0.4 0.1 0.0 1.4 0.3 0.1 0.1 7.4 0.3 0.7 0.3 0.0 0.9 9.7 13.6 4.5 16.3 9.7 11.9 10.8 9.7 13.2 6.4 11.9 20.0 0.0 12.5 30.5 7.7 38.3 15.3 6.7 7.9 17.4 9.8 17.1 5.0 16.3 0.5 65.3 16.9 0.0 36.7 25.2 46.6 8.5 5.7 10.5 6.7 11.1 11.7 58.9 6.2 0.7 33.9 4.5 57.3 3.6 27.2 34.3 30.2 17.5 51.9 7.4 4.5 45.3 51.9 0.9 0.9 25.0 11.0 1.3 21.4 8.6 FMO1 ENSG00000010932 "Flavin containing monooxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 70.4" "Cell type enriched" "Detected in some" 12 "Proximal tubular cells: 142.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 36 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 36 "B-cells: 3.5" "Cell line enriched" "Detected in some" 7 "HSkMC: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA078132 Approved NA NA "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 3.4 3.6 0.1 0.1 0.3 0.0 5.6 0.1 0.4 5.6 0.8 0.3 0.8 0.0 2.5 3.0 5.0 3.3 1.8 0.9 0.1 0.0 70.4 1.0 0.8 0.1 0.1 0.1 5.9 2.4 0.1 1.1 0.8 0.2 1.1 0.0 4.0 4.2 1.5 0.1 4.0 14.4 1.5 0.1 0.1 0.5 1.6 0.1 1.8 1.7 5.3 10.3 1.4 1.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.4 2.9 0.0 8.7 5.1 0.0 0.0 3.5 0.0 0.2 11.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 10.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 2.5 142.2 0.0 6.5 1.4 0.0 0.0 1.9 0.7 0.0 0.0 0.0 FMO2 ENSG00000094963 "Flavin containing monooxygenase 2" Q99518 1 171185208-171211230 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.0;esophagus: 35.3;lung: 53.0" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 428.8;Club cells: 348.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 57 "ASC diff: 24.6;ASC TERT1: 11.2;HSkMC: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA028261 Approved NA NA "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" 40.0 11.8 1.2 1.7 4.4 0.0 22.5 1.5 0.6 7.6 5.0 0.6 2.9 0.3 1.9 3.5 35.3 6.7 2.0 17.4 1.8 1.2 9.4 1.8 53.0 5.7 3.9 1.2 6.1 2.1 1.8 7.0 0.0 2.4 6.0 0.7 8.3 14.0 1.3 7.6 1.7 1.5 2.5 1.9 0.4 2.4 3.3 1.3 0.4 5.8 6.8 5.5 5.0 10.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 29.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.2 4.4 1.5 0.6 1.8 1.2 3.9 1.2 2.4 1.3 428.8 20.8 0.0 5.3 0.3 0.2 6.9 0.0 62.9 348.1 1.8 0.0 0.0 0.0 0.0 2.7 5.3 0.0 0.0 0.0 0.0 0.6 3.0 3.5 0.0 0.0 0.0 0.0 4.3 0.0 2.3 0.9 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.4 0.2 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 1.1 FMO3 ENSG00000007933 "Flavin containing monooxygenase 3" P31513 1 171090877-171117819 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 170.2" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 378.8" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Region enriched" "Detected in single" 5 "pons and medulla: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 25.4;ASC TERT1: 19.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favorable (3.46e-4)" "prognostic favorable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 9.5 2.0 0.0 0.8 0.2 0.0 1.3 0.1 0.1 0.2 0.8 0.1 0.1 0.3 0.6 1.2 1.7 2.3 0.3 0.8 0.0 0.1 6.4 170.2 3.7 1.5 0.2 0.0 0.9 0.7 0.3 2.7 0.0 1.4 0.2 0.1 3.6 0.9 0.1 1.9 0.8 0.4 0.2 0.1 0.1 0.6 0.5 0.1 0.0 0.8 1.2 2.6 0.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.4 19.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 5.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.0 1.4 0.1 11.9 0.3 0.9 0.3 0.3 0.0 0.3 5.1 32.1 27.3 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.9 0.1 0.0 378.8 0.0 0.0 0.0 4.9 6.9 0.0 0.3 0.0 1.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 6.5 3.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 FMO4 FMO2 ENSG00000076258 "Flavin containing monooxygenase 4" P31512 1 171314208-171342084 "Enzymes, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 33.8;liver: 42.2" "Cell type enhanced" "Detected in many" 10 "Distal tubular cells: 24.9;Hepatocytes: 19.8;Proximal tubular cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 7.9;HSkMC: 9.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" 5.3 3.6 1.4 5.1 4.8 0.9 4.5 0.6 2.7 4.5 6.0 4.8 3.1 4.2 3.0 10.0 4.6 3.8 4.6 6.3 2.3 1.5 33.8 42.2 3.4 2.8 7.5 2.8 4.1 3.2 5.5 5.0 2.3 3.7 3.9 3.7 6.7 2.7 2.0 1.6 2.9 16.1 2.0 7.0 3.8 3.9 2.0 6.2 2.7 4.5 3.3 3.4 2.9 3.7 5.3 2.9 0.9 4.0 3.9 4.9 2.0 0.1 0.0 0.4 0.6 5.5 5.0 0.2 1.1 5.0 1.6 1.7 0.8 7.2 4.4 7.9 0.0 2.6 0.3 0.8 1.3 2.2 2.1 1.1 0.0 0.0 0.1 0.8 0.9 1.0 9.3 3.2 0.6 1.3 0.6 0.3 2.2 0.2 3.3 0.7 1.0 2.1 1.9 0.5 1.3 1.6 0.4 0.5 2.5 3.5 0.0 0.2 0.0 1.5 1.5 3.0 5.7 3.1 1.3 0.1 1.3 0.4 1.4 1.0 4.0 1.3 2.7 2.4 1.5 1.1 0.6 2.6 0.9 2.5 4.0 1.8 3.1 2.4 3.3 2.2 5.3 3.3 2.5 0.5 3.9 2.7 2.9 4.9 2.0 1.4 4.8 0.6 2.7 2.3 1.5 7.5 2.8 3.7 6.2 0.0 1.6 0.5 3.8 2.5 0.0 3.5 2.5 6.7 0.0 8.7 0.0 2.1 24.9 1.6 4.0 0.9 8.6 0.0 1.2 1.2 3.1 1.1 1.1 19.8 3.2 0.0 1.2 1.8 5.7 0.4 1.4 2.3 5.0 1.8 1.9 1.5 0.9 0.0 0.4 33.2 0.0 0.0 1.2 0.2 0.2 1.4 1.6 0.5 1.4 1.7 FMO5 ENSG00000131781 "Flavin containing monooxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 61.1;liver: 119.4;stomach 1: 38.6" "Cell type enhanced" "Detected in many" 17 "Cholangiocytes: 117.2;Hepatocytes: 260.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Group enriched" "Detected in many" 6 "basal ganglia: 5.5;cerebral cortex: 4.5;midbrain: 17.1;pons and medulla: 5.2;thalamus: 6.0" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Hep G2: 29.0;HMC-1: 6.6;THP-1: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 1.1 2.4 1.1 1.9 5.5 0.2 8.6 0.6 4.5 1.3 61.1 1.5 0.8 12.5 1.0 1.3 0.7 1.1 8.5 1.0 1.3 0.5 9.0 119.4 17.0 0.8 17.1 0.5 1.0 11.9 8.8 4.9 0.6 5.2 1.9 8.2 0.5 9.7 0.6 0.4 4.2 53.6 0.9 7.1 1.2 38.6 1.2 6.0 0.2 1.1 1.5 0.5 1.9 0.8 9.2 4.9 6.2 12.1 1.0 2.0 3.6 0.1 0.7 0.5 0.1 1.9 0.5 0.7 0.4 0.4 0.2 0.6 0.4 1.5 0.3 0.5 0.4 0.1 0.3 0.0 0.0 0.0 1.0 0.1 1.2 0.0 29.0 0.6 1.0 6.6 0.9 0.1 0.3 0.0 0.3 0.4 0.2 0.1 0.1 1.1 1.0 0.2 0.5 2.1 3.6 0.5 0.3 0.3 0.2 2.4 0.4 0.4 0.2 0.6 2.0 0.9 1.0 1.4 7.4 0.7 0.0 0.2 0.6 0.0 0.2 0.0 0.2 0.7 0.3 0.2 6.2 12.1 3.5 2.0 5.6 0.3 3.6 0.5 0.6 4.9 9.2 0.3 1.3 1.2 1.0 1.6 2.4 1.4 3.6 1.1 5.5 0.6 4.5 1.3 0.5 17.1 0.5 5.2 6.0 8.9 48.6 8.5 3.5 1.4 2.0 1.4 117.2 21.4 13.6 14.0 0.0 1.2 6.6 4.3 5.9 2.7 52.0 0.0 5.1 0.9 1.3 4.1 5.7 260.8 3.2 3.2 6.4 3.1 10.1 4.1 2.6 2.6 27.0 0.0 25.3 0.3 5.7 28.1 1.4 41.5 1.3 0.0 0.8 1.8 0.7 1.4 1.1 4.3 16.4 6.2 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735575-82751197 "Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 45.2;Distal tubular cells: 76.3;Rod photoreceptor cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 17.8;Hep G2: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 1400000 Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 12.0 29.4 25.7 3.1 32.7 8.9 5.0 24.8 48.1 10.0 11.0 44.8 6.4 19.4 7.8 7.0 4.7 11.9 6.6 38.1 24.7 22.8 41.7 34.7 7.4 2.6 28.9 25.3 14.0 14.9 17.9 11.9 5.2 34.2 10.4 8.8 11.4 24.6 11.9 14.8 5.0 12.4 6.6 30.8 4.4 10.7 4.6 25.3 0.0 8.2 3.5 2.7 5.6 4.5 0.2 0.0 0.0 0.0 0.9 0.4 0.2 0.6 8.2 2.3 12.1 3.7 3.1 1.5 1.5 1.1 2.8 1.4 10.7 1.7 0.1 2.1 1.3 2.4 0.3 17.8 1.3 1.0 0.5 1.2 6.3 6.8 33.0 10.1 0.1 5.3 2.6 4.7 1.1 0.0 3.0 5.5 0.5 11.1 0.3 0.5 0.9 0.1 0.1 1.5 3.8 6.8 1.0 0.2 0.0 6.0 2.3 3.7 11.9 2.7 0.6 7.7 2.1 8.0 2.3 1.2 0.2 0.8 2.9 2.2 0.6 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.2 25.7 32.7 24.8 48.1 24.7 22.8 28.9 25.3 34.2 25.3 3.0 1.3 1.4 2.7 1.3 35.7 5.1 2.5 1.4 2.3 29.6 45.2 9.7 76.3 3.2 0.0 2.1 9.2 0.0 1.0 1.9 4.3 3.2 1.1 4.7 6.5 30.2 5.2 4.9 1.2 0.0 4.9 2.0 11.8 1.0 10.1 26.8 2.2 7.0 2.8 38.4 70.5 0.0 5.1 0.3 3.6 1.6 7.0 1.3 8.6 3.0 FN3KRP "FLJ12171, FN3KL" ENSG00000141560 "Fructosamine 3 kinase related protein" Q9HA64 17 82716683-82730328 "Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Cytotrophoblasts: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056172, HPA065831" Approved Approved Nucleoplasm NA NA 14000 Nucleoplasm "HPA056172: AB_2683055, HPA065831: AB_2685565" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (1.54e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.31e-1)" "unprognostic (1.25e-2)" "unprognostic (8.67e-2)" "unprognostic (1.26e-1)" "unprognostic (1.99e-1)" "unprognostic (8.84e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (3.97e-2)" "unprognostic (3.71e-2)" 17.6 18.3 27.9 10.8 26.3 12.3 15.7 19.5 27.3 15.3 17.4 27.4 10.0 11.8 18.4 16.7 16.4 16.6 13.0 12.7 26.1 20.8 18.8 23.1 12.8 12.9 25.7 23.0 21.9 15.3 10.8 11.4 17.1 22.2 17.1 14.4 13.2 17.2 20.0 7.3 16.1 13.6 20.3 30.7 13.7 12.6 8.8 21.6 8.2 15.1 9.8 17.5 12.1 12.9 16.5 23.2 18.5 15.5 18.5 23.0 17.1 10.9 44.3 12.1 16.0 5.9 11.3 10.0 20.6 11.5 19.9 16.3 23.4 7.7 9.0 13.8 16.6 18.4 12.6 11.0 15.6 18.0 6.0 19.5 15.1 24.8 26.9 10.5 10.5 8.5 10.4 18.5 18.9 10.4 12.2 14.3 12.8 14.5 5.7 25.4 20.8 20.5 15.6 5.5 24.1 19.3 15.4 30.8 14.0 14.1 21.1 10.1 21.5 34.0 15.4 16.6 21.9 25.7 15.3 12.6 38.7 13.3 27.3 30.3 11.7 12.8 22.4 18.0 13.4 17.8 17.0 14.2 18.5 20.4 15.5 20.0 15.7 19.9 19.5 11.7 16.5 23.0 16.7 2.1 18.5 8.4 23.2 18.6 17.1 27.9 26.3 19.5 27.3 26.1 20.8 25.7 23.0 22.2 21.6 11.9 12.0 13.7 25.9 13.4 17.8 5.2 20.4 10.7 12.5 10.4 7.9 80.4 19.9 17.2 1.3 11.7 9.5 23.3 9.9 35.3 15.1 14.6 12.7 9.0 28.7 3.2 7.5 11.6 9.4 2.3 26.2 11.8 21.9 28.9 13.3 29.2 14.9 17.3 29.7 15.8 14.3 12.9 17.6 9.7 22.6 13.4 52.3 14.9 16.9 21.3 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" NA NA "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favorable (7.41e-4)" 16.5 18.9 16.8 42.2 22.7 29.9 16.7 32.4 27.7 18.0 32.5 19.7 18.6 48.2 22.4 18.6 23.7 20.5 26.8 11.4 16.2 13.9 25.0 22.1 22.2 22.4 17.6 19.4 21.1 33.0 19.5 18.9 16.6 17.9 20.3 15.2 16.9 70.8 20.6 26.2 25.6 41.1 15.2 14.3 30.9 39.2 28.6 18.5 23.6 19.7 19.2 22.3 18.9 18.9 4.7 7.1 10.8 19.3 4.0 8.5 6.9 15.9 12.8 7.8 13.3 7.9 6.8 20.2 15.1 9.1 10.4 8.7 16.2 22.8 13.6 10.3 9.1 18.8 13.9 8.1 12.5 4.9 13.8 14.2 15.7 12.9 12.1 14.8 16.0 24.8 9.8 10.8 10.5 5.1 6.6 11.4 16.2 16.9 17.3 7.0 15.4 27.0 41.3 14.0 17.0 23.5 22.4 9.1 12.1 8.4 13.0 13.5 14.7 8.8 11.2 10.5 6.9 18.0 13.8 18.6 14.5 8.5 14.7 20.1 28.0 18.7 15.1 16.4 19.6 13.3 2.6 9.0 10.8 8.5 8.9 7.4 4.7 5.6 5.7 6.0 4.0 3.2 4.7 6.7 4.0 19.3 7.1 5.0 6.9 16.8 22.7 32.4 27.7 16.2 13.9 17.6 19.4 17.9 18.5 23.8 28.6 15.3 12.6 15.0 27.8 9.5 15.3 16.0 22.7 24.4 60.9 16.1 8.3 16.1 102.1 20.4 83.6 0.0 24.3 13.5 15.3 23.7 17.4 25.9 31.3 11.1 28.3 21.5 37.8 102.9 23.3 25.0 15.1 16.2 53.5 15.6 29.1 45.8 17.7 26.4 25.2 19.4 15.3 30.2 26.3 19.4 26.0 27.3 45.3 36.3 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501689-19522145 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Syncytiotrophoblasts: 226.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved Vesicles NA NA Vesicles "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 20.3 18.5 30.6 11.7 34.3 17.5 23.9 13.5 32.2 18.1 31.0 24.5 23.0 22.7 15.0 22.6 19.0 13.4 17.5 40.7 31.1 17.5 21.1 21.3 22.1 13.1 29.2 20.6 9.9 28.3 35.3 13.9 15.5 20.8 21.4 32.5 12.5 20.4 24.9 42.4 18.5 20.8 27.2 25.3 10.1 22.8 14.8 23.8 9.6 17.9 21.7 12.7 22.8 12.4 4.6 7.4 23.9 12.4 3.7 7.4 4.6 14.8 17.9 9.8 11.7 47.6 17.6 14.2 15.4 26.4 12.0 14.9 10.2 26.6 11.1 19.8 22.3 13.2 12.9 13.7 18.1 14.6 12.1 21.2 9.3 17.6 21.9 28.9 12.2 8.7 18.5 29.4 12.8 15.0 22.3 16.1 14.5 5.1 11.6 13.0 26.8 10.7 11.3 11.5 23.3 13.9 15.4 18.1 16.1 29.7 22.8 11.5 10.5 14.9 17.9 14.2 15.9 18.3 14.7 16.9 10.2 9.1 13.4 9.4 10.9 10.2 7.8 15.6 18.2 9.0 23.9 11.8 6.4 5.7 10.5 7.3 4.6 6.8 6.6 7.4 3.7 3.6 5.7 19.8 3.7 12.4 4.6 7.4 4.6 30.6 34.3 13.5 32.2 31.1 17.5 29.2 20.6 20.8 23.8 35.7 72.1 27.9 29.4 20.8 14.8 63.5 35.7 26.8 26.1 8.7 25.5 63.8 19.9 79.5 27.6 16.8 94.2 23.3 143.1 66.0 28.2 77.4 3.5 20.0 53.4 30.2 32.1 17.8 30.7 51.5 26.4 32.5 23.6 22.6 50.6 19.8 66.9 87.7 35.7 39.2 21.5 12.9 25.5 71.0 39.2 25.7 226.1 21.8 61.0 49.4 GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 22.5;intestine: 19.5;lymphoid tissue: 37.5;skin 1: 33.2" "Cell type enhanced" "Detected in some" 16 "Basal keratinocytes: 50.5;Enterocytes: 47.9;Muller glia cells: 24.7" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "AF22: 9.4;NTERA-2: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" 0.4 0.4 6.8 0.6 5.7 0.4 1.0 1.1 4.0 0.3 13.0 8.2 8.3 8.0 0.4 22.5 0.4 0.5 0.5 0.8 7.6 4.0 0.6 0.3 0.4 0.4 4.3 5.6 0.4 0.4 0.3 2.6 0.4 8.4 0.3 3.0 0.2 1.1 0.6 0.6 33.2 19.5 0.4 1.5 37.5 1.6 0.3 4.9 0.0 0.4 0.6 0.3 1.0 0.3 0.4 0.1 1.4 0.2 0.1 0.2 0.0 0.0 0.0 9.4 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 20.2 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 0.4 0.1 0.1 1.4 0.1 0.1 0.1 0.0 0.0 6.8 5.7 1.1 4.0 7.6 4.0 4.3 5.6 8.4 4.9 0.0 0.0 0.0 0.0 50.5 0.1 1.4 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 3.1 0.5 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 24.7 0.1 2.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 10.7 2.7 0.0 1.5 0.1 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24583750-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 54.1;seminal vesicle: 41.7" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 74.5;Alveolar cells type 2: 21.4;Cholangiocytes: 40.8;Ductal cells: 54.8;Enterocytes: 80.7;Hepatocytes: 34.1;Pancreatic endocrine cells: 33.5;Paneth cells: 23.0;Proximal tubular cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 35.6;Karpas-707: 52.5;OE19: 37.9;RPMI-8226: 51.6;RPTEC TERT1: 48.0" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 4600000 Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 1.6 0.5 1.7 1.7 2.2 2.7 8.2 2.3 2.6 7.3 7.9 1.6 23.7 22.3 1.4 19.9 1.2 0.8 12.2 2.0 1.8 1.2 54.1 29.2 14.3 3.2 1.7 1.6 1.3 17.3 0.0 1.6 1.4 2.2 14.7 2.4 1.4 8.7 41.7 0.9 1.1 20.9 1.7 1.9 4.7 6.6 5.0 2.1 2.4 4.8 1.6 5.5 2.1 1.1 3.3 7.5 15.9 14.6 6.6 8.6 6.6 0.2 19.3 0.2 0.0 0.0 0.1 0.5 0.1 0.6 0.2 0.2 2.6 4.2 0.2 4.3 0.0 3.8 2.8 1.4 0.2 0.1 35.6 2.9 0.1 8.6 14.0 1.5 0.3 11.9 0.4 0.2 0.6 0.4 0.3 0.1 5.3 2.0 52.5 0.2 0.4 0.3 14.6 1.4 37.9 0.2 0.2 2.2 51.6 48.0 0.6 0.2 0.3 0.1 9.3 0.2 5.5 9.3 11.1 2.2 3.5 2.3 10.8 0.3 15.8 5.9 0.2 7.4 15.0 0.1 5.2 14.6 0.4 1.4 6.8 5.2 3.3 7.7 3.4 7.5 0.3 1.0 1.9 15.9 6.6 5.5 0.1 8.6 6.6 1.7 2.2 2.3 2.6 1.8 1.2 1.7 1.6 2.2 2.1 74.5 21.4 3.4 0.1 0.7 0.4 0.4 40.8 2.7 7.9 1.8 0.0 0.9 1.7 54.8 1.1 0.1 80.7 0.0 7.2 0.3 1.3 3.0 5.7 34.1 4.7 0.0 1.2 2.5 3.0 4.1 0.0 2.9 1.7 5.4 2.5 2.0 33.5 23.0 0.4 32.7 0.0 0.0 0.2 0.6 0.7 0.4 0.7 3.2 4.2 0.0 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 5.6;salivary gland: 5.5;thyroid gland: 8.4" "Cell type enhanced" "Detected in some" 23 "Alveolar cells type 1: 3.0;Alveolar cells type 2: 7.4;Early spermatids: 3.8;Late spermatids: 14.7" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;HeLa: 4.6;Karpas-707: 2.0;U-2197: 13.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.1 0.2 0.0 1.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.1 2.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.3 1.0 8.4 0.0 0.0 0.0 0.1 0.2 0.4 0.4 0.4 0.5 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.0 0.0 1.0 0.0 1.5 0.0 0.0 0.1 0.5 0.6 13.9 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.3 0.1 0.5 0.0 0.2 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.5 0.3 3.0 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245142 "Enzymes, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 19 "Ito cells: 44.2;Sertoli cells: 181.1;Smooth muscle cells: 82.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.0;eosinophil: 7.5;neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 7.5" "Group enriched" "Detected in some" 4 "ASC diff: 39.5;ASC TERT1: 30.1;HHSteC: 56.4;HSkMC: 65.0;TIME: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 18000000 "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 20.2 14.8 2.0 5.2 3.5 0.0 13.2 0.5 4.2 10.7 4.0 5.7 7.9 3.6 2.1 10.2 12.1 14.0 2.4 3.4 13.1 13.7 5.1 12.4 4.7 3.9 5.0 2.2 6.0 3.2 6.5 3.4 5.4 6.8 2.5 5.3 7.2 10.1 2.7 4.8 5.6 1.2 17.2 5.2 6.3 9.3 0.1 0.4 7.5 0.9 0.8 0.1 0.4 0.0 0.3 0.0 0.0 39.5 30.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.1 5.2 56.4 0.6 1.4 65.0 0.0 0.7 0.7 0.0 10.6 0.1 0.1 0.1 10.1 0.1 0.0 4.9 0.6 0.1 0.0 0.0 0.9 0.1 1.1 0.0 0.0 1.4 0.0 1.7 0.0 5.6 0.2 0.3 25.2 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.1 0.0 4.0 0.9 7.5 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.9 0.8 0.0 0.1 0.0 0.4 3.0 16.5 0.5 3.1 6.3 0.0 4.8 0.0 2.7 11.4 0.0 0.0 0.2 0.0 0.1 0.5 37.5 0.0 0.0 0.2 0.1 8.7 1.3 1.1 0.0 1.6 0.0 0.0 44.2 1.2 2.6 33.6 2.9 3.3 5.4 0.0 0.2 0.3 0.0 22.3 0.0 0.4 181.1 82.1 0.3 0.4 3.9 0.2 0.0 0.0 0.9 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;salivary gland: 52.7" "Cell type enhanced" "Detected in many" 10 "Enterocytes: 136.8;Mucus-secreting cells: 63.3;Paneth cells: 98.2;Undifferentiated cells: 77.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.5" "Group enriched" "Detected in some" 8 "RT4: 30.5;SK-BR-3: 10.4;T-47d: 32.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 33000 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.4 0.3 12.7 0.3 0.0 3.2 0.3 0.4 4.1 24.9 0.4 1.0 17.0 0.9 15.9 25.2 3.0 7.7 0.3 0.3 0.1 18.8 0.6 4.2 0.3 0.3 0.3 1.5 28.6 0.0 1.0 0.4 0.4 5.7 12.7 0.4 52.7 3.7 0.3 25.2 40.4 2.8 0.3 0.3 8.7 0.8 0.3 1.0 0.7 19.6 18.8 16.5 8.2 0.6 0.7 3.5 0.5 0.6 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 30.5 0.1 0.1 0.0 10.4 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.5 0.2 0.4 0.3 0.2 0.3 0.5 0.3 0.1 0.6 0.5 0.4 1.9 0.6 0.5 0.7 0.4 0.0 0.3 0.3 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.3 32.8 5.8 2.2 16.1 3.7 0.0 0.2 17.8 33.5 29.6 22.7 2.0 0.0 18.3 16.4 0.0 0.0 136.8 0.0 33.4 0.0 0.3 3.4 0.0 0.0 0.1 0.0 5.8 0.0 0.0 0.0 0.6 1.3 0.0 3.6 63.3 0.2 14.4 98.2 0.0 32.1 0.2 0.0 1.0 0.0 0.1 18.2 0.0 0.5 77.9 19.7 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872860 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Bipolar cells: 38.6;Horizontal cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 1500000 Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: AB_2668816" "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 6.8 6.7 21.6 6.7 23.7 2.9 8.5 42.6 29.1 9.5 11.5 9.7 14.3 9.8 12.3 19.5 6.4 10.5 11.4 13.8 19.7 17.0 9.9 7.2 9.0 10.3 11.2 32.1 13.4 19.5 20.8 18.3 8.5 19.2 11.4 9.6 6.9 18.8 15.3 31.6 11.1 9.0 9.6 11.0 8.3 12.9 5.0 15.6 4.9 16.3 4.3 8.2 9.3 8.5 6.1 2.6 1.5 3.0 3.2 12.8 1.8 2.2 3.3 17.0 17.4 13.4 12.0 15.1 9.4 9.6 7.8 11.6 17.4 11.1 0.0 11.2 7.3 7.9 1.5 7.3 4.1 5.1 0.7 13.1 6.7 5.9 9.1 12.0 0.3 11.1 17.4 4.7 8.7 4.0 23.3 0.6 8.9 5.0 1.2 5.3 3.8 1.7 3.4 3.9 3.8 1.7 0.0 11.6 10.7 11.3 3.3 9.9 11.6 4.8 7.7 12.1 6.7 5.9 6.1 0.2 26.8 10.7 2.5 5.3 13.1 1.7 0.8 31.5 0.6 9.8 1.5 3.0 1.4 7.4 2.0 2.1 5.6 6.3 2.8 2.6 6.1 12.8 8.9 0.3 3.2 0.7 1.4 4.8 1.8 21.6 23.7 42.6 29.1 19.7 17.0 11.2 32.1 19.2 15.6 3.0 2.4 0.9 17.1 6.5 38.6 1.6 22.9 1.4 3.4 17.4 11.8 18.6 0.0 13.9 2.1 2.1 10.5 0.0 4.9 9.8 11.9 9.2 2.3 10.2 4.0 38.1 10.4 0.6 1.9 0.5 11.5 2.4 10.1 3.6 16.0 9.4 6.7 14.0 7.4 5.1 16.9 6.5 8.6 11.1 10.6 3.8 14.1 4.1 17.8 12.0 GGTLC2 GGTL4 ENSG00000100121 "Gamma-glutamyltransferase light chain 2" Q14390 22 22644475-22647903 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 11.1" "Cell type enhanced" "Detected in some" 18 "Alveolar cells type 1: 20.8;Early spermatids: 22.5;Late spermatids: 5.2;Spermatocytes: 10.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 1.6;RPMI-8226: 4.6;THP-1: 2.8;U-2 OS: 2.4" "HPA045635, HPA047534" Uncertain NA NA "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (2.58e-2)" "unprognostic (2.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.96e-1)" "unprognostic (4.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.06e-3)" "unprognostic (1.48e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.0 0.3 0.9 1.4 1.3 0.8 0.7 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 4.6 1.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.3 2.8 0.0 0.0 2.4 0.0 0.0 0.7 0.5 0.1 0.0 0.2 0.0 0.5 1.3 0.0 0.0 0.5 0.2 0.3 0.7 0.4 0.9 0.0 0.0 0.3 1.4 0.8 0.7 0.0 0.7 0.6 20.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 5.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 10.9 0.1 0.0 0.0 0.0 0.0 0.0 GGTLC3 ENSG00000274252 "Gamma-glutamyltransferase light chain family member 3" B5MD39 22 18516344-18518161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 4.2;salivary gland: 3.0" "Group enriched" "Detected in some" 21 "Alveolar cells type 1: 3.0;Early spermatids: 4.1;Late spermatids: 10.4;Spermatocytes: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.9;SuSa: 5.3;U-2197: 3.6" "HPA045635, HPA047534" Uncertain NA NA "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (1.37e-1)" "unprognostic (2.06e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 1.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.5 1.2 0.0 0.0 1.2 0.3 0.0 0.7 0.6 1.1 0.3 0.0 0.0 5.3 0.0 0.0 0.0 0.3 1.4 3.6 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996608-33097230 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease mutation, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 139.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 1700000 Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 17.3 33.1 9.6 14.9 14.7 9.5 18.4 8.9 19.8 18.3 21.9 12.1 19.8 21.2 18.3 55.0 12.7 15.2 25.8 13.7 9.7 10.0 35.0 33.2 24.3 25.0 9.2 9.7 18.3 25.3 28.4 16.4 26.5 14.0 13.6 23.7 23.5 21.1 17.7 6.1 12.9 28.3 15.6 9.8 21.4 22.7 10.0 8.0 8.3 26.9 7.7 19.5 18.4 13.6 11.1 45.2 22.7 39.2 6.8 20.9 20.9 5.8 10.0 6.5 7.7 39.9 20.7 139.7 9.3 25.2 12.0 15.4 14.2 13.8 2.8 8.3 19.0 8.9 5.6 6.1 11.9 8.9 16.3 5.1 11.2 6.0 7.3 20.5 7.7 11.4 23.9 11.4 10.8 6.4 23.6 18.4 3.9 10.1 10.9 13.1 6.8 4.6 5.1 4.4 12.2 4.4 4.0 4.3 13.2 12.9 8.5 2.0 6.8 12.0 19.4 11.7 12.0 12.9 20.4 10.7 7.7 5.4 10.5 7.9 8.6 13.7 0.9 16.2 11.2 5.8 10.5 39.2 22.7 8.3 34.6 11.8 11.1 10.2 9.1 45.2 10.0 5.4 6.5 15.5 6.8 23.7 9.5 20.9 20.9 9.6 14.7 8.9 19.8 9.7 10.0 9.2 9.7 14.0 8.0 17.9 22.3 15.9 10.2 5.4 11.3 7.1 35.7 14.7 17.0 26.2 5.9 80.5 23.2 42.1 22.3 10.5 31.5 0.0 31.3 47.6 24.4 11.4 26.5 36.5 70.6 4.8 16.3 18.4 38.2 3.1 14.1 38.3 13.5 81.2 22.4 20.0 27.0 39.5 19.8 24.2 15.0 12.9 10.8 1.1 7.2 3.0 41.1 20.0 28.4 8.4 GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236606-219245478 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.0" "Cell type enhanced" "Detected in many" 12 "Spermatocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 18.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043058 Enhanced "Secreted - unknown location" NA NA "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" 6.9 5.4 2.7 2.0 3.7 2.3 5.6 1.6 3.3 4.0 5.8 4.6 4.5 1.6 5.3 7.9 2.5 14.3 8.6 3.4 3.1 3.5 18.5 3.5 4.1 2.5 2.1 2.1 6.1 3.1 11.7 6.7 7.4 5.6 4.5 2.0 13.2 5.8 3.0 1.4 2.5 4.4 3.4 2.3 3.9 2.1 57.0 1.4 3.1 5.0 1.4 2.4 4.0 2.0 1.7 2.8 3.2 8.9 1.4 1.8 2.2 2.4 4.3 6.7 5.4 7.4 9.1 3.4 4.1 8.7 5.2 4.9 1.6 6.9 0.8 3.7 3.6 3.9 1.3 1.9 4.0 4.1 2.2 3.3 2.5 6.2 3.9 18.3 0.9 4.0 10.8 2.5 4.9 3.0 12.3 4.6 3.8 1.5 4.8 4.8 3.5 2.1 2.5 1.1 0.9 1.2 2.2 3.7 3.4 10.5 1.4 4.3 3.9 3.4 4.8 4.0 4.7 7.5 2.2 3.6 4.4 5.3 2.5 2.2 4.6 1.3 1.3 8.1 1.1 11.0 2.0 7.0 0.5 1.1 8.9 0.6 0.6 0.9 1.1 2.8 1.7 1.8 1.3 3.2 1.4 6.7 1.2 0.3 2.2 2.7 3.7 1.6 3.3 3.1 3.5 2.1 2.1 5.6 1.4 3.0 3.2 0.8 2.5 1.5 4.8 1.7 2.5 24.1 7.9 3.5 11.8 2.9 3.3 3.1 21.1 2.5 2.1 0.0 1.6 1.5 4.4 2.7 0.0 1.0 11.7 3.2 4.7 9.8 6.1 17.2 10.0 4.5 8.5 1.0 2.8 3.5 1.7 2.3 6.0 15.3 9.5 6.5 1.2 80.3 5.4 1.5 1.1 2.1 1.7 1.6 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase alpha and beta subunits" Q3T906 12 101745497-101830938 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease mutation, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "granulocytes: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 47000 "Golgi apparatus" "HPA014558: AB_2732409, HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favorable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 15.2 6.5 21.9 11.9 23.0 15.2 12.2 13.9 25.6 14.0 21.3 10.3 5.9 10.3 9.0 6.5 11.7 7.1 11.0 15.9 17.9 13.7 11.0 7.3 19.6 20.3 14.4 13.0 6.6 11.4 29.9 9.0 10.8 10.9 15.6 22.5 11.3 37.6 10.2 10.8 18.1 14.5 11.7 13.1 15.4 15.2 7.4 10.8 24.5 10.5 8.6 12.6 14.7 14.8 3.9 5.8 5.9 3.4 14.2 16.4 2.7 8.2 8.0 3.0 5.1 25.3 12.0 9.3 11.8 24.3 11.7 15.4 6.1 5.8 17.3 8.5 16.1 9.6 10.8 13.8 15.1 18.3 8.1 7.3 7.4 7.4 8.7 4.7 6.7 15.0 9.3 8.4 11.1 6.6 29.2 20.4 13.9 11.5 5.2 10.9 12.5 20.2 9.5 10.3 10.2 5.8 4.8 15.4 23.2 18.8 21.5 6.5 5.3 19.5 14.0 27.7 11.7 14.3 4.4 20.1 11.1 6.0 9.2 6.5 14.2 14.5 9.9 12.6 10.0 6.8 5.9 3.1 3.4 16.4 2.9 5.4 2.4 3.6 8.9 5.8 3.9 4.6 7.1 1.2 14.2 3.4 5.8 2.6 2.7 21.9 23.0 13.9 25.6 17.9 13.7 14.4 13.0 10.9 10.8 56.6 54.2 24.1 31.6 14.9 24.2 36.8 20.4 9.4 29.6 21.0 23.6 20.7 6.6 9.5 0.4 12.7 22.0 0.0 13.2 12.5 11.8 33.9 118.0 8.3 40.7 7.9 17.3 8.0 31.8 2.2 15.8 35.6 40.5 40.5 27.1 29.3 13.7 74.8 12.0 13.3 35.5 0.0 10.3 8.9 30.9 12.5 7.3 61.8 37.4 40.8 GRHL1 "LBP-32, MGR, TFCP2L2" ENSG00000134317 "Grainyhead like transcription factor 1" Q9NZI5 2 9951693-10002277 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.3;skin 1: 34.4" "Cell type enhanced" "Detected in many" 9 "Extravillous trophoblasts: 69.0;Suprabasal keratinocytes: 115.9;Syncytiotrophoblasts: 154.4;Urothelial cells: 97.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 4.8;neutrophil: 1.7" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.8" "Group enriched" "Detected in some" 4 "BEWO: 66.4;SK-BR-3: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA005798, HPA006420" Enhanced Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA005798: AB_1079026, HPA006420: AB_1079025" "unprognostic (2.26e-3)" "unprognostic (5.80e-2)" "unprognostic (8.35e-2)" "unprognostic (7.33e-3)" "unprognostic (2.70e-1)" "unprognostic (2.76e-2)" "unprognostic (4.43e-3)" "unprognostic (6.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-4)" "unprognostic (3.66e-1)" "unprognostic (3.40e-1)" "unprognostic (4.04e-2)" "unprognostic (2.14e-1)" 1.7 0.6 1.5 0.2 2.4 2.8 15.9 2.0 1.6 10.2 0.9 0.2 10.8 0.3 0.9 3.8 40.3 0.7 1.0 1.6 1.9 1.2 2.5 4.9 2.3 0.2 0.7 1.4 0.5 1.5 12.9 2.6 31.0 0.8 6.1 0.2 1.8 17.5 9.7 0.9 34.4 0.7 5.1 0.6 0.6 1.3 1.6 0.4 0.4 2.8 22.3 25.3 6.7 16.9 0.1 0.2 4.8 0.2 0.5 0.6 4.5 3.2 0.0 0.4 0.9 0.1 0.1 66.4 0.3 0.4 0.2 0.3 0.2 2.3 0.4 0.1 0.0 0.4 2.0 4.0 0.4 0.9 0.9 1.8 0.1 0.6 1.2 0.0 0.2 0.3 0.1 1.7 1.9 0.0 0.0 0.3 0.7 0.6 1.2 0.0 4.2 0.6 0.5 0.2 1.0 0.7 0.2 0.3 0.5 0.4 12.6 0.7 0.5 0.6 34.9 0.8 5.7 4.2 0.1 0.3 0.2 0.8 1.0 0.4 0.8 0.5 0.4 0.2 0.5 0.5 0.0 0.2 4.8 0.1 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 1.7 0.5 0.0 0.0 0.6 4.5 1.5 2.4 2.0 1.6 1.9 1.2 0.7 1.4 0.8 0.4 3.0 7.2 0.0 18.6 35.5 20.9 1.2 0.0 6.7 29.6 19.2 58.9 48.9 0.0 2.8 6.0 3.1 0.5 0.0 8.0 69.0 6.1 30.1 10.3 5.7 6.7 11.1 3.4 3.1 1.3 2.1 0.0 2.7 20.3 1.0 0.6 1.7 4.8 0.0 0.4 1.7 11.8 0.0 6.1 5.1 5.3 115.9 154.4 1.3 0.4 97.4 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667155-113737735 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "retina: 51.5" "Group enriched" "Detected in some" 26 "Cone photoreceptor cells: 53.0;Rod photoreceptor cells: 86.9" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced NA NA "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 86.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266410-67286556 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.2" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 2: 26.5;granulocytes: 19.8;Hofbauer cells: 31.0;monocytes: 15.4;Pancreatic endocrine cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 56.3;REH: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA048330" Enhanced Approved Vesicles NA NA Vesicles "CAB005021: AB_562360, CAB037248: AB_1078280, HPA048330: AB_2680361" "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 13.1 10.7 24.5 35.8 17.0 78.2 17.0 32.9 35.3 12.8 17.2 12.2 12.6 17.5 11.4 9.9 20.2 12.6 17.6 13.6 21.9 17.4 13.0 14.1 19.1 42.8 13.4 19.0 9.8 10.4 9.7 12.2 12.7 15.7 17.8 16.2 9.3 17.4 20.8 20.8 23.5 26.3 12.2 12.5 59.6 17.4 6.8 11.1 35.9 10.1 13.6 37.5 17.1 15.5 4.1 6.0 21.0 18.3 3.8 5.3 7.4 7.6 5.4 5.3 8.9 4.3 3.9 5.3 4.6 4.4 6.3 5.2 12.0 12.8 39.5 7.4 4.2 8.4 10.4 7.7 6.2 3.3 48.1 4.8 22.4 6.2 5.4 5.3 47.0 45.0 3.5 7.3 5.0 6.7 4.7 8.0 16.2 8.1 20.3 5.4 14.3 26.1 56.3 6.6 23.1 8.2 74.7 10.5 11.7 6.4 10.1 10.7 5.8 6.8 10.0 16.3 3.4 9.2 51.1 4.4 5.0 6.6 6.3 5.1 12.9 11.9 35.4 6.5 27.9 4.5 6.9 10.3 10.5 5.3 15.9 4.0 3.8 4.0 4.3 6.0 4.1 3.2 3.1 21.0 3.8 18.3 5.3 2.6 7.4 24.5 17.0 32.9 35.3 21.9 17.4 13.4 19.0 15.7 11.1 3.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 7.9 5.2 0.0 7.8 1.7 9.4 0.0 0.0 0.0 0.0 10.9 5.1 0.0 0.0 19.8 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 15.4 0.0 0.0 22.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564849-25729294 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.0" "Cell type enhanced" "Detected in many" 10 "Alveolar cells type 2: 44.1;Club cells: 30.7;Extravillous trophoblasts: 22.7;Hofbauer cells: 25.0;monocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.8;eosinophil: 5.6;intermediate monocyte: 8.0;memory B-cell: 4.9;myeloid DC: 3.7;naive B-cell: 6.2;non-classical monocyte: 7.4;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 20.4;JURKAT: 33.6;SH-SY5Y: 18.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 28.0 6.0 11.9 12.4 10.8 7.0 11.3 7.9 18.9 4.7 4.0 3.1 0.7 3.0 5.7 3.1 2.7 9.1 5.0 4.6 15.7 8.3 3.0 3.4 9.4 14.1 9.7 9.8 4.1 8.4 4.4 8.2 4.5 9.6 8.2 4.3 4.8 3.7 1.9 1.4 4.1 6.1 6.2 4.9 23.2 4.0 14.8 2.7 11.6 4.5 1.3 15.2 6.7 2.5 6.2 3.7 5.6 8.0 0.0 0.4 1.6 0.0 1.9 5.8 1.9 4.1 0.5 8.5 0.6 1.8 1.8 3.2 3.0 3.3 10.6 0.1 0.1 5.2 0.1 5.8 4.3 5.5 20.4 3.8 4.9 0.6 6.7 0.1 15.8 8.3 1.0 3.0 1.3 2.3 0.3 0.3 33.6 0.5 0.0 2.1 2.6 11.3 1.1 4.1 5.7 0.0 5.1 9.3 1.8 0.0 3.1 13.7 18.5 1.0 0.0 4.4 5.6 1.6 6.3 0.1 0.0 12.0 0.1 2.3 1.2 4.2 8.3 7.8 5.6 1.8 0.6 4.8 5.6 0.0 8.0 0.3 4.9 0.0 0.3 3.7 6.2 0.1 0.2 0.3 0.0 7.4 3.2 0.4 1.6 11.9 10.8 7.9 18.9 15.7 8.3 9.7 9.8 9.6 2.7 14.9 44.1 0.0 0.0 0.0 0.0 0.0 0.0 12.0 30.7 0.0 0.0 1.5 1.7 7.0 0.0 0.0 0.0 0.0 1.6 22.7 0.0 0.0 17.4 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 47.7 0.0 0.0 3.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 2.4" "Cell type enriched" "Detected in some" 168 "Cone photoreceptor cells: 310.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 4.1;HeLa: 1.5;U-937: 1.8" "Not detected" "Not detected" "HPA075093, HPA078232" Enhanced Approved Mitochondria NA NA Mitochondria "HPA075093: , HPA078232: " "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.2 0.5 0.3 0.5 0.4 1.5 0.2 0.9 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.3 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.2 0.2 0.6 0.3 0.7 0.2 0.2 0.3 0.0 0.4 0.2 1.6 1.5 0.4 0.0 0.2 0.4 0.1 1.0 0.1 0.3 0.1 0.3 0.7 0.2 2.4 0.4 0.5 0.6 0.1 0.0 0.1 0.1 0.6 0.4 0.0 4.1 0.1 0.0 0.0 0.1 0.2 0.6 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.5 0.5 0.2 1.5 0.2 0.0 0.4 0.3 0.1 1.1 0.0 0.1 0.0 0.0 0.3 0.2 0.2 0.0 0.2 0.2 0.7 0.4 0.2 0.2 0.2 0.1 0.2 0.0 0.5 0.3 0.4 0.2 0.0 0.0 0.2 0.5 0.2 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 1.8 0.2 0.2 0.4 0.3 0.4 0.2 0.6 0.6 0.5 0.3 0.1 0.7 0.5 0.5 2.4 0.5 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.2 0.0 0.0 0.0 0.0 310.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379569-6393981 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 199.3;Late spermatids: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "HPA022793: AB_1857946, HPA028707: AB_2672745, HPA070752: AB_2732163" "unprognostic (1.30e-2)" "unprognostic (6.05e-3)" "unprognostic (2.00e-1)" "prognostic favorable (8.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.99e-2)" "unprognostic (6.45e-3)" "unprognostic (6.96e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.92e-2)" "unprognostic (4.25e-1)" 24.9 26.0 32.5 26.6 33.1 41.1 22.6 60.7 47.3 25.5 24.7 18.8 26.1 35.2 31.7 22.6 30.8 29.9 26.5 22.9 28.9 25.9 24.4 21.7 19.8 34.9 23.9 36.3 59.8 40.7 31.8 33.4 19.9 26.6 24.6 16.3 22.3 33.9 24.4 25.6 21.8 31.9 27.6 26.4 26.7 26.4 39.4 23.1 23.6 36.4 19.7 22.2 26.0 39.8 24.4 21.5 28.4 21.4 19.0 23.8 14.1 38.3 28.3 20.6 32.7 13.9 22.6 16.3 27.0 25.3 33.7 32.2 29.6 15.2 23.4 38.0 17.7 24.2 35.0 19.3 17.1 16.6 35.7 24.6 32.5 21.1 26.3 24.2 37.6 26.4 23.7 22.9 24.0 18.4 28.6 19.8 23.2 39.6 31.8 18.6 26.7 37.3 21.4 37.3 17.8 36.1 34.6 22.8 29.9 18.8 22.0 25.3 34.8 27.9 21.4 29.8 13.0 27.2 30.0 28.0 26.5 22.3 45.7 38.0 56.5 63.4 25.3 33.0 39.5 29.6 7.0 21.4 14.0 20.5 20.6 23.8 24.4 18.4 19.5 16.9 23.3 21.7 18.8 28.4 19.0 19.1 21.5 17.6 14.1 32.5 33.1 60.7 47.3 28.9 25.9 23.9 36.3 26.6 23.1 44.7 44.6 45.7 42.2 21.6 25.9 26.2 20.4 115.1 78.5 24.4 7.9 38.5 18.3 42.3 199.3 33.5 64.5 23.3 44.2 36.6 30.1 27.3 60.3 23.7 51.8 23.8 29.2 52.8 50.9 301.8 41.1 31.9 32.1 62.3 38.4 32.6 42.6 35.9 46.7 29.3 28.8 32.3 43.2 51.5 36.8 18.3 45.2 56.5 40.9 36.7 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694955 "Enzymes, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria No No Nucleoplasm Mitochondria "HPA069369: AB_2686130" "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 6.9 8.5 12.3 6.6 11.6 7.8 11.6 23.8 13.9 10.8 8.0 7.0 5.6 5.3 10.2 9.3 11.4 9.5 7.4 7.8 8.7 8.1 8.7 7.4 8.9 10.9 9.4 11.6 15.0 8.4 16.6 10.1 9.7 8.9 8.9 7.7 7.6 11.3 8.4 11.6 14.5 6.6 8.6 5.6 6.3 8.1 16.9 6.4 11.6 13.3 5.3 9.3 8.8 7.9 2.3 2.1 1.5 1.5 2.1 3.1 0.9 8.5 12.2 15.5 13.3 7.7 9.1 11.2 8.2 10.9 11.7 8.6 14.9 6.4 13.3 5.6 10.7 10.9 19.8 23.7 13.5 13.0 8.0 9.8 11.2 17.6 6.3 7.6 16.5 7.1 7.0 10.3 12.0 15.7 7.1 10.0 8.9 18.2 6.8 8.4 14.0 10.1 7.7 19.7 13.0 11.9 10.0 18.9 11.7 8.6 7.2 21.6 14.6 14.8 15.0 9.1 10.1 20.9 6.8 10.4 19.4 10.9 8.8 12.3 2.8 6.4 14.8 8.2 10.4 11.9 0.1 1.5 1.2 2.5 1.3 2.0 2.3 2.2 3.1 1.2 2.2 2.3 2.4 1.5 2.1 1.2 2.1 2.0 0.9 12.3 11.6 23.8 13.9 8.7 8.1 9.4 11.6 8.9 6.4 17.9 8.6 7.8 6.7 27.2 15.0 11.2 2.5 18.7 6.8 3.5 13.7 6.2 6.6 7.2 4.8 9.0 3.5 0.0 5.4 6.0 11.5 9.1 1.1 7.8 5.4 19.1 12.6 7.4 7.3 2.1 17.5 4.6 3.3 2.8 7.4 11.3 5.8 7.0 18.0 5.6 16.9 0.0 7.6 15.1 12.6 35.0 5.4 6.1 8.0 4.6 HACE1 KIAA1320 ENSG00000085382 "HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1" Q8IYU2 6 104728093-104859919 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 41.9" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 43.2;Rod photoreceptor cells: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046071 Supported "Nuclear bodies,Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "Nuclear bodies" "HPA046071: AB_2679524" "unprognostic (6.32e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (1.12e-2)" "unprognostic (3.75e-2)" "unprognostic (3.75e-3)" "unprognostic (1.22e-3)" "unprognostic (4.63e-2)" "unprognostic (7.41e-2)" "unprognostic (1.24e-1)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.12e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (1.75e-1)" 6.4 5.4 12.7 3.7 16.1 4.3 6.1 15.5 13.1 6.6 4.8 6.8 2.5 3.6 8.5 2.9 8.1 5.4 5.0 5.2 7.5 8.6 9.4 2.9 5.7 3.5 8.8 9.6 6.4 3.8 12.0 7.4 41.9 10.2 6.1 3.3 7.7 6.2 6.9 4.4 4.8 3.6 6.5 9.5 4.1 3.9 14.1 8.9 5.4 7.1 2.7 3.9 6.4 5.8 2.9 2.4 2.2 2.9 2.2 3.9 1.6 3.6 2.5 10.9 13.6 6.5 8.7 12.9 7.3 11.3 4.6 7.0 2.3 2.1 2.1 3.3 5.5 7.9 2.5 2.7 5.0 9.8 8.4 6.9 7.2 2.3 3.1 6.5 6.2 2.4 5.8 4.6 6.0 5.1 6.1 7.6 8.7 6.9 2.3 9.1 2.6 4.6 3.7 4.7 2.7 2.5 7.3 12.4 0.8 3.7 6.2 5.8 8.8 3.9 4.1 2.1 7.3 2.6 8.5 8.0 3.7 3.1 10.0 6.9 3.3 3.7 7.0 3.9 5.9 6.8 0.0 1.9 2.2 3.7 2.9 3.9 2.9 3.7 3.6 1.9 2.7 3.9 3.0 0.4 2.2 1.5 2.4 1.2 1.6 12.7 16.1 15.5 13.1 7.5 8.6 8.8 9.6 10.2 8.9 3.0 0.6 0.0 1.6 4.1 11.4 6.3 2.5 0.0 4.5 5.2 43.2 7.5 1.7 1.7 3.1 6.7 1.3 0.0 1.3 4.6 4.8 2.2 1.1 2.5 4.6 15.9 1.7 4.3 2.2 3.3 5.8 2.4 1.7 4.6 1.4 5.8 1.1 2.9 3.5 4.1 30.6 6.5 6.6 12.5 2.7 4.1 5.3 2.2 2.1 1.8 HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983682 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB037191: AB_477070, HPA036788: AB_10672267" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (8.24e-3)" "unprognostic (2.76e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.71e-2)" "unprognostic (9.08e-3)" "unprognostic (3.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (6.89e-2)" "unprognostic (1.80e-1)" "unprognostic (3.97e-2)" "unprognostic (6.69e-2)" 24.3 23.7 14.3 20.8 21.4 30.9 25.7 18.4 16.7 17.6 18.2 14.0 17.7 11.8 20.7 15.6 21.3 17.7 14.8 26.2 16.7 13.0 27.5 22.1 18.8 26.9 21.2 12.9 21.8 23.0 22.3 32.2 21.1 21.4 20.8 19.3 13.1 25.5 15.6 53.9 18.6 15.8 22.9 20.5 22.5 20.2 15.9 21.5 35.4 26.1 31.8 27.8 22.1 16.9 21.0 16.0 29.9 32.1 25.9 28.1 19.2 34.2 16.4 29.0 26.5 15.4 16.0 20.5 35.8 23.9 39.6 41.4 38.0 23.8 38.5 23.2 21.6 33.6 27.3 31.4 29.3 61.2 21.7 31.1 33.9 27.1 34.3 7.5 42.8 21.3 9.5 17.0 52.2 17.5 12.5 24.9 26.9 35.1 25.3 44.9 23.9 33.5 39.2 24.1 41.8 17.2 26.9 36.6 26.1 23.5 34.6 18.6 15.3 30.0 16.8 30.4 23.4 23.4 43.5 12.6 35.6 27.5 29.9 36.0 11.1 25.6 45.3 24.0 30.7 30.8 23.8 21.1 29.9 20.8 24.5 25.8 21.0 22.1 21.3 16.0 18.4 22.2 24.2 24.0 25.9 32.1 8.2 28.1 19.2 14.3 21.4 18.4 16.7 16.7 13.0 21.2 12.9 21.4 21.5 32.8 31.1 44.9 101.4 65.9 23.1 47.4 17.8 45.5 30.7 26.2 31.4 65.0 69.6 36.4 42.5 37.9 16.0 23.3 40.9 71.6 41.6 50.0 40.3 18.4 45.8 27.0 13.7 28.3 32.7 8.9 28.4 37.8 30.4 19.0 18.1 49.8 25.8 18.2 34.6 35.3 35.7 38.8 59.0 45.9 63.7 46.0 48.7 40.6 27.7 61.2 HDAC3 "HD3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636870 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: AB_2681708" "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favorable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" 15.9 28.8 19.6 12.2 17.6 18.1 18.6 22.6 20.8 15.6 14.1 11.2 13.1 10.6 17.3 17.6 22.8 16.3 14.0 16.8 18.0 8.9 14.5 23.3 24.4 36.4 13.4 14.2 17.3 24.7 20.9 17.3 14.3 18.8 13.6 14.4 13.6 17.5 13.7 24.5 26.7 15.2 17.2 10.8 20.1 15.5 11.9 12.6 18.5 14.4 9.6 23.7 17.5 17.0 22.1 46.7 16.4 22.6 14.1 23.1 16.9 21.3 14.5 27.0 40.9 26.1 20.8 17.5 15.6 34.3 35.4 50.8 31.0 18.3 31.1 20.2 20.2 25.2 18.6 27.1 36.5 43.9 26.5 29.1 24.3 13.3 17.6 18.4 29.2 22.3 17.7 23.5 20.5 26.8 18.4 22.8 28.1 23.7 16.6 22.3 20.2 32.4 25.3 23.8 13.3 11.5 23.5 28.2 22.4 18.9 21.5 22.6 18.3 20.6 21.4 25.7 17.9 22.8 18.5 11.5 22.0 13.8 16.8 25.5 13.5 16.6 29.3 18.5 27.8 18.8 13.2 22.4 16.4 15.9 22.6 20.8 22.1 19.8 19.2 46.7 20.1 21.7 18.0 9.5 14.1 19.0 23.9 23.1 16.9 19.6 17.6 22.6 20.8 18.0 8.9 13.4 14.2 18.8 12.6 8.9 10.4 32.3 23.0 39.3 30.6 12.3 15.3 5.3 11.4 12.2 56.9 47.2 18.3 28.5 7.6 20.2 15.4 0.0 31.4 44.3 29.3 18.8 18.4 14.8 34.9 47.7 17.2 20.9 15.4 3.4 20.8 33.0 30.4 66.7 17.7 27.7 27.2 14.0 20.8 15.7 30.4 25.8 24.0 22.3 24.5 44.9 51.1 31.9 22.7 26.5 HECTD1 KIAA1131 ENSG00000092148 "HECT domain E3 ubiquitin protein ligase 1" Q9ULT8 14 31100112-31207804 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Urothelial cells: 267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002929, HPA054461" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA002929: AB_1850574, HPA054461: AB_2682496" "unprognostic (6.71e-2)" "unprognostic (4.86e-2)" "unprognostic (5.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (6.99e-2)" "unprognostic (1.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.29e-2)" "unprognostic (3.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.51e-1)" "prognostic favorable (1.20e-6)" "unprognostic (6.53e-2)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (9.91e-3)" 22.0 22.3 14.2 21.0 16.8 22.0 18.5 22.3 18.9 19.4 17.9 15.2 20.2 11.5 17.6 15.7 30.4 16.1 15.2 26.2 13.5 14.3 18.0 35.2 15.0 14.1 14.5 14.5 18.2 15.1 34.8 20.5 27.0 18.8 16.8 15.5 16.8 18.9 16.4 88.5 24.3 16.3 15.6 13.7 16.4 18.8 18.9 14.4 16.7 24.8 23.0 18.6 18.6 22.3 10.6 9.3 12.6 8.6 8.9 8.1 3.3 28.8 18.1 15.9 9.9 50.4 26.4 15.2 17.7 17.9 15.8 13.7 13.5 15.7 22.7 18.8 32.3 11.3 19.6 21.2 16.0 24.1 13.9 8.7 23.2 14.9 54.0 23.5 24.1 17.0 23.2 22.1 17.8 28.0 22.0 29.1 13.5 16.6 10.5 24.6 23.7 9.3 10.3 12.1 25.3 16.5 17.3 18.4 9.9 24.7 30.0 11.8 13.9 25.9 18.0 15.7 20.2 18.9 15.6 29.1 18.4 14.4 13.2 15.0 11.5 16.4 25.6 8.7 12.2 15.5 12.6 8.6 11.3 7.1 7.1 8.1 7.2 8.0 6.3 9.3 10.6 6.7 6.6 4.4 8.9 5.3 7.8 8.0 3.3 14.2 16.8 22.3 18.9 13.5 14.3 14.5 14.5 18.8 14.4 44.7 63.3 37.1 68.0 76.9 78.2 103.0 22.9 155.2 84.2 68.0 92.3 53.4 10.0 37.6 2.9 56.2 38.8 23.3 31.4 36.2 49.1 82.9 31.3 79.7 25.8 62.0 46.8 39.9 39.7 6.7 63.9 34.4 32.1 29.7 30.4 36.8 41.9 28.1 70.0 20.0 175.8 45.3 41.2 53.4 107.2 100.5 117.1 37.4 37.3 267.3 HECTD2 FLJ37306 ENSG00000165338 "HECT domain E3 ubiquitin protein ligase 2" Q5U5R9 10 91409280-91514829 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 25.5;Horizontal cells: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 7 "NK-cell: 6.7" "Lineage enriched" "Detected in many" 7 "NK-cells: 6.7" "Cell line enhanced" "Detected in many" "AF22: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037767 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA037767: AB_10671378" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.26e-2)" "unprognostic (3.34e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-2)" "unprognostic (9.37e-4)" "unprognostic (1.42e-1)" "unprognostic (1.59e-1)" "unprognostic (2.31e-1)" "unprognostic (2.54e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.67e-5)" "unprognostic (6.98e-3)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.84e-2)" 8.7 8.8 16.5 6.9 17.9 2.4 10.8 20.3 19.5 14.3 10.1 5.1 9.1 4.6 17.2 16.6 8.3 12.1 11.4 8.1 11.9 8.7 7.3 4.7 8.7 4.7 5.8 11.3 16.8 7.4 14.4 18.6 10.2 6.5 24.8 7.6 7.5 7.7 24.3 7.7 6.8 6.0 18.4 6.8 5.3 7.5 9.7 6.4 2.9 9.8 5.1 3.6 13.7 10.5 0.6 0.4 0.1 0.8 6.7 1.0 0.5 4.1 2.1 21.4 8.8 4.7 5.2 3.8 3.4 4.5 6.9 6.3 0.2 3.9 0.0 2.9 3.4 4.0 0.3 5.8 2.4 8.5 4.4 7.2 2.4 15.0 1.3 2.4 0.4 1.6 5.3 2.2 5.0 4.3 9.7 5.1 5.1 3.1 10.7 10.6 1.9 2.5 1.3 8.9 0.4 2.1 6.4 14.1 2.4 4.8 1.2 5.0 5.4 6.6 1.5 6.7 6.9 9.7 1.4 5.4 6.9 4.8 0.5 6.3 0.7 1.4 5.9 6.1 0.0 4.0 0.0 0.1 0.0 1.0 0.8 0.6 0.2 0.5 0.7 0.4 0.6 0.5 0.6 0.1 6.7 0.2 0.0 0.1 0.5 16.5 17.9 20.3 19.5 11.9 8.7 5.8 11.3 6.5 6.4 0.0 3.2 0.0 7.0 5.5 21.3 6.5 5.1 5.3 5.7 5.2 25.5 0.3 18.3 2.4 1.5 8.3 0.7 0.0 3.0 0.3 11.3 4.2 3.5 0.8 5.3 27.0 8.6 9.2 7.0 1.5 11.2 3.8 6.8 3.6 3.0 12.0 2.5 0.6 13.4 1.3 8.2 12.9 7.6 6.7 8.1 3.9 0.3 1.5 1.3 3.0 HECTD3 FLJ21156 ENSG00000126107 "HECT domain E3 ubiquitin protein ligase 3" Q5T447 1 45002540-45011329 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027467 Approved NA NA 34000 "HPA027467: AB_10600710" "unprognostic (1.86e-1)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.14e-5)" "unprognostic (1.74e-2)" "unprognostic (2.92e-2)" "unprognostic (7.42e-2)" "unprognostic (2.47e-1)" "unprognostic (8.39e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.35e-1)" "prognostic favorable (1.85e-6)" "unprognostic (3.19e-1)" 18.4 16.9 9.6 16.7 11.1 9.2 25.9 12.4 14.8 11.2 38.0 14.8 11.7 34.1 12.4 12.4 16.7 9.1 14.6 8.7 9.9 8.4 16.4 22.9 10.5 11.3 10.9 7.9 14.1 24.1 22.9 8.0 11.8 10.8 10.4 19.5 9.7 27.0 15.4 24.2 20.1 59.3 12.0 9.9 14.0 13.9 11.7 9.7 11.9 13.3 14.8 12.5 13.8 12.0 8.7 9.9 10.4 15.1 5.0 10.9 7.5 11.1 10.1 6.5 10.5 22.9 14.4 12.9 10.7 16.2 11.8 13.4 14.4 3.5 5.2 9.1 17.5 26.5 10.5 15.4 11.1 10.6 9.8 11.9 8.4 14.7 12.6 20.1 6.5 14.2 15.5 19.1 20.1 7.9 12.3 26.3 9.2 18.8 5.9 15.0 9.5 8.2 5.3 8.9 12.6 15.5 9.9 11.8 7.5 17.3 13.2 15.7 6.5 14.4 25.0 12.7 17.2 8.1 6.1 19.6 13.7 11.0 16.9 12.1 7.6 8.9 2.9 21.9 7.1 6.7 9.4 10.4 10.4 10.9 15.1 9.1 8.7 8.9 9.3 9.9 5.1 7.5 8.9 4.0 5.0 8.2 7.5 9.0 7.5 9.6 11.1 12.4 14.8 9.9 8.4 10.9 7.9 10.8 9.7 3.0 8.0 3.0 2.3 3.4 5.3 5.5 7.6 0.0 6.8 5.2 5.9 6.1 1.7 8.5 1.0 4.6 34.5 23.3 13.5 12.8 6.0 2.1 5.8 10.5 12.1 6.4 2.4 5.5 16.5 1.3 13.6 5.4 3.3 8.2 13.7 3.9 11.3 23.0 9.2 5.5 5.9 6.5 4.1 4.5 7.7 5.4 5.0 5.0 11.5 2.0 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112599-43566001 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;kidney: 15.4" "Group enriched" "Detected in some" 4 "Early spermatids: 118.3;Horizontal cells: 42.9;Late spermatids: 44.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 5.5;GAMG: 4.9;U-266/70: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Approved Supported Cytosol NA NA Cytosol "HPA007203: AB_2667776, HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.7 0.5 10.3 0.8 12.1 1.4 0.8 13.6 24.0 0.6 0.8 1.1 0.0 0.4 0.8 1.7 2.6 0.5 4.0 0.4 3.9 4.1 15.4 0.6 0.6 1.3 3.8 15.5 1.0 0.4 1.7 0.4 0.6 10.2 3.2 0.5 0.6 1.0 0.8 1.8 2.1 0.6 0.7 1.4 0.6 1.0 3.7 1.6 0.0 1.5 0.0 0.8 1.2 0.6 2.4 1.6 7.0 1.7 1.6 0.7 0.1 0.1 5.5 0.6 0.8 0.0 0.0 0.0 1.6 2.8 0.1 0.7 0.0 0.0 0.2 3.1 2.7 4.9 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.4 0.2 0.2 1.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 3.0 0.0 0.0 0.0 0.0 2.4 0.1 0.9 0.5 0.0 0.0 0.0 0.1 0.2 0.7 0.5 0.1 0.0 0.3 0.4 0.0 0.0 0.8 1.1 1.3 0.4 15.7 0.5 0.0 3.5 0.4 0.0 6.4 1.7 1.1 0.7 1.0 0.5 1.0 0.7 0.3 0.2 2.4 0.6 0.7 7.0 1.6 0.9 1.6 0.2 0.1 10.3 12.1 13.6 24.0 3.9 4.1 3.8 15.5 10.2 1.6 0.0 0.0 0.0 0.3 0.3 13.6 1.2 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 118.3 0.3 2.0 0.0 0.0 0.1 0.8 0.5 0.0 0.0 0.0 42.9 0.0 0.6 0.0 44.2 0.3 0.4 0.0 0.0 0.0 0.5 0.0 0.6 0.4 15.9 1.8 0.0 0.8 2.1 2.5 0.3 0.0 0.5 0.4 0.3 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593692 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Ito cells: 134.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 7.7;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 9 "granulocytes: 7.7;monocytes: 5.2" "Cell line enhanced" "Detected in many" "HDLM-2: 27.2;HUVEC TERT2: 15.3;SCLC-21H: 17.8;TIME: 20.1;U-138 MG: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034609 Enhanced NA NA "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 8.8 3.3 6.7 2.6 12.6 0.6 4.2 15.7 17.2 4.6 1.2 11.6 0.0 1.1 3.0 1.0 5.5 6.3 4.8 14.0 6.7 4.3 3.4 5.6 16.4 3.5 8.2 9.3 1.3 2.1 14.7 5.9 15.5 9.5 1.5 1.3 1.2 2.2 1.3 2.7 2.7 1.7 3.1 5.8 11.6 2.1 5.8 8.8 0.0 7.9 1.6 4.2 2.4 2.5 0.6 0.7 7.7 5.2 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.7 2.4 0.9 1.5 4.0 1.2 1.5 0.1 0.0 0.7 0.3 7.3 1.9 1.7 0.5 0.1 2.5 27.2 0.9 0.0 1.1 0.1 0.1 0.2 0.2 0.6 0.7 9.1 3.2 2.3 15.3 0.0 0.1 0.0 3.7 1.0 0.0 0.3 1.4 0.1 0.6 0.0 0.3 0.0 0.0 0.0 17.8 1.4 1.1 0.2 0.0 0.2 0.0 0.1 20.1 12.3 0.8 2.6 0.3 0.1 0.0 0.7 3.1 0.0 0.1 0.2 0.5 1.3 0.0 1.9 0.0 0.5 0.1 0.0 0.7 0.6 0.1 0.0 7.7 0.0 5.2 0.0 0.1 0.1 6.7 12.6 15.7 17.2 6.7 4.3 8.2 9.3 9.5 8.8 0.0 8.9 2.7 0.2 1.9 7.8 14.2 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 9.7 18.0 0.0 0.0 0.0 0.2 1.0 0.1 1.1 1.5 0.1 0.0 2.4 134.4 11.6 3.6 0.0 1.1 3.3 1.0 0.0 12.5 0.1 0.0 2.5 0.0 0.9 0.0 2.1 0.5 6.4 1.4 0.1 1.9 0.0 0.4 HELZ2 "KIAA1769, PDIP1, PRIC285" ENSG00000130589 "Helicase with zinc finger 2" Q9BYK8 20 63558086-63574239 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Urothelial cells: 49.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 33.2;GAMG: 19.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA051267 Uncertain NA NA "HPA051267: " "unprognostic (1.86e-1)" "unprognostic (7.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.93e-3)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.36e-2)" "unprognostic (5.06e-2)" "unprognostic (1.52e-1)" "unprognostic (1.73e-2)" "unprognostic (3.61e-2)" "unprognostic (2.19e-3)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (9.76e-2)" "unprognostic (1.16e-1)" 3.2 2.1 0.7 4.6 0.9 13.3 3.1 0.0 0.7 2.4 2.4 3.1 2.3 0.3 4.2 2.9 2.5 2.7 0.3 0.7 3.5 4.6 5.8 3.6 0.7 2.2 3.7 0.7 3.1 1.8 2.4 0.4 10.4 0.7 1.1 2.4 3.4 0.6 0.6 9.5 5.6 0.5 3.5 1.3 2.2 1.9 0.9 0.4 2.7 0.8 0.3 0.8 0.8 5.2 2.0 0.6 2.0 1.2 1.6 3.9 1.9 2.8 33.2 12.9 5.4 6.8 0.1 4.1 0.7 19.2 8.3 0.4 2.0 1.3 2.0 0.9 0.1 2.2 1.8 2.7 0.1 13.0 2.0 1.4 2.4 0.4 0.7 1.5 0.1 0.9 2.2 0.4 5.2 0.6 5.4 1.0 1.4 6.2 1.2 1.1 2.0 0.9 6.1 0.5 1.8 5.9 0.4 13.4 0.4 1.8 1.6 2.4 3.2 4.8 2.6 1.9 2.9 0.3 0.1 3.4 0.9 2.8 0.4 0.8 1.9 0.8 0.6 0.3 0.4 0.5 0.6 0.4 0.9 0.3 0.5 2.7 0.3 0.4 0.0 0.5 0.8 8.9 8.9 1.4 18.9 7.7 1.0 3.7 10.2 1.4 10.3 8.7 0.0 1.6 0.0 7.8 0.0 13.7 16.3 0.0 6.7 11.3 7.8 25.2 0.0 4.0 3.1 0.0 29.6 6.7 2.7 0.0 6.6 11.6 3.3 1.8 13.3 2.8 14.0 10.7 2.1 0.6 2.7 6.5 7.6 0.6 0.2 7.3 1.6 13.8 10.4 49.9 HERC1 "p532, p619" ENSG00000103657 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 1" Q15751 15 63608618-63833942 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049749 Uncertain NA NA "HPA049749: AB_2680866" "unprognostic (9.72e-2)" "unprognostic (7.51e-2)" "unprognostic (3.43e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-1)" "prognostic favorable (4.87e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (2.89e-3)" "prognostic favorable (3.66e-4)" "unprognostic (1.24e-1)" "prognostic favorable (1.36e-6)" "unprognostic (2.87e-1)" "unprognostic (3.36e-2)" "unprognostic (9.04e-3)" "unprognostic (3.94e-1)" 14.4 11.7 20.3 12.9 23.5 28.9 15.5 30.4 29.7 17.4 15.3 14.7 13.8 7.0 15.8 8.9 10.3 10.7 12.1 17.6 19.4 14.3 11.9 11.4 14.9 15.2 12.8 23.7 23.8 11.5 44.8 20.1 12.7 19.1 11.4 11.8 11.0 11.4 14.0 31.7 14.6 13.9 15.7 11.7 17.4 13.5 13.5 15.8 16.6 17.2 11.3 15.3 12.9 11.6 9.8 7.0 17.6 5.7 2.8 6.6 1.4 7.5 9.9 11.1 3.8 19.7 12.7 3.7 6.0 7.7 6.2 7.2 6.1 3.0 11.3 5.5 11.2 5.7 8.3 17.9 5.1 8.5 8.7 6.1 24.5 14.1 4.4 3.2 18.1 14.7 9.0 5.0 8.7 8.6 5.4 13.0 7.7 24.6 5.0 5.3 12.3 6.3 3.6 5.5 5.8 5.1 6.9 12.3 6.6 2.5 18.7 10.0 5.0 10.6 7.2 6.3 14.0 3.6 7.2 14.5 8.1 7.5 6.9 7.8 5.6 9.5 7.9 4.6 13.5 2.8 17.6 3.7 7.4 5.0 3.3 3.8 5.3 5.5 4.4 3.2 9.8 5.6 5.6 12.9 2.8 5.7 7.0 6.6 1.4 20.3 23.5 30.4 29.7 19.4 14.3 12.8 23.7 19.1 15.8 6.0 36.1 26.8 9.3 13.3 57.2 57.0 7.6 18.7 20.5 21.0 62.8 7.2 1.7 8.7 18.5 26.3 11.5 0.0 12.2 9.1 17.5 12.6 48.6 17.9 15.0 81.0 9.8 51.5 39.1 12.5 25.6 22.8 18.6 23.4 12.8 25.1 10.8 13.6 37.4 13.2 54.8 6.5 17.8 45.5 28.9 13.4 7.4 34.8 12.0 9.3 HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322152 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "CAB017188: , HPA048389: AB_2680382, HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favorable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" 2.5 3.3 3.2 2.2 4.5 3.9 3.1 7.0 5.7 3.2 4.6 2.7 4.4 1.7 2.8 4.1 2.1 4.6 3.5 3.6 3.3 1.6 2.5 2.1 3.8 8.5 3.6 9.2 3.5 2.7 3.0 3.0 2.3 3.3 8.2 3.1 3.1 4.1 4.1 2.3 3.4 3.2 5.6 2.4 3.3 2.3 1.0 1.1 0.5 0.4 0.2 1.1 0.4 5.2 10.3 7.2 3.0 6.0 4.5 2.0 3.8 4.5 4.9 4.7 5.3 0.7 5.2 4.6 6.4 7.4 5.3 7.6 3.7 3.6 3.2 4.9 33.3 12.0 1.7 2.3 7.8 2.7 3.7 2.9 5.8 7.3 3.1 6.4 4.4 12.8 2.2 4.6 2.4 1.7 2.6 2.1 4.0 4.5 6.2 10.3 0.4 1.7 11.3 7.9 4.6 9.1 2.6 3.0 3.9 3.0 9.2 9.6 9.1 5.9 3.5 5.6 1.4 2.0 4.9 4.2 3.7 4.8 0.0 0.4 0.5 1.1 0.1 0.6 0.5 0.2 0.5 1.1 1.0 0.9 0.5 0.0 0.2 0.3 0.9 0.4 0.4 20.8 19.7 23.1 13.0 14.5 100.9 54.0 28.1 17.4 25.0 61.1 139.4 22.6 1.7 24.7 11.1 39.4 24.9 0.0 26.5 13.6 21.3 18.7 3.5 30.6 16.6 116.0 27.0 36.8 21.8 10.6 52.0 17.3 65.8 26.2 29.8 46.8 29.3 31.6 49.1 16.6 140.1 64.7 24.7 57.9 59.4 18.3 14.9 30.2 30.9 10.1 HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592423-88708542 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Cone photoreceptor cells: 104.1;Rod photoreceptor cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 27.6;hTERT-HME1: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039170 Approved Approved Cytosol NA NA Cytosol "HPA039170: AB_10673414" "unprognostic (2.21e-2)" "unprognostic (1.65e-2)" "unprognostic (9.28e-3)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.51e-3)" "unprognostic (3.48e-3)" "unprognostic (2.58e-2)" "prognostic favorable (5.65e-7)" "unprognostic (1.83e-1)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" 12.7 13.3 16.9 13.0 27.1 21.0 15.3 37.8 20.1 14.4 12.0 17.9 11.6 11.2 12.0 10.5 16.8 10.7 12.1 22.0 15.2 13.7 15.8 13.0 15.0 15.3 21.9 15.0 12.7 9.7 33.8 16.1 10.0 21.1 22.0 13.4 22.0 14.0 14.0 17.3 19.1 12.8 13.8 16.3 15.7 12.9 3.6 21.5 16.6 15.7 12.6 16.4 13.3 16.7 5.2 7.0 18.2 9.7 3.1 9.0 3.9 7.3 1.1 1.4 2.4 7.9 16.7 4.7 8.3 15.4 8.7 5.8 1.9 8.6 7.8 4.0 27.6 4.0 2.6 2.0 7.6 8.3 3.4 2.3 5.4 3.3 1.2 4.5 13.4 9.8 7.9 9.4 8.3 37.6 4.9 9.6 4.1 3.9 3.4 17.7 2.2 9.2 3.2 0.4 4.8 2.0 10.4 9.7 3.2 5.6 1.4 1.9 1.9 9.6 6.1 3.2 2.4 1.0 6.0 15.0 9.9 5.4 9.3 6.2 6.5 1.6 4.5 6.2 6.1 4.1 5.7 5.7 7.7 4.7 6.2 5.5 5.2 5.5 4.7 7.0 4.9 8.2 5.8 18.2 3.1 9.7 2.4 9.0 3.9 16.9 27.1 37.8 20.1 15.2 13.7 21.9 15.0 21.1 21.5 6.0 5.8 8.8 7.9 31.9 24.1 18.5 7.6 4.0 2.3 8.7 104.1 5.8 1.7 3.6 2.6 9.3 9.2 23.3 7.9 13.2 7.3 12.5 15.1 11.0 8.3 30.2 26.5 8.6 27.9 2.7 7.8 17.3 13.5 2.8 10.1 9.2 7.4 8.6 12.4 5.0 59.1 6.5 11.3 3.0 7.0 44.4 6.2 13.1 5.2 10.4 HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075348 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 55.9;fHDF/TERT166: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045453, HPA070301" Uncertain Supported "Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoli fibrillar center" "HPA045453: AB_10961917, HPA070301: AB_2686247" "unprognostic (3.66e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (4.23e-2)" "unprognostic (3.51e-2)" "unprognostic (1.01e-3)" "unprognostic (3.54e-1)" "unprognostic (8.57e-2)" "unprognostic (4.94e-3)" "unprognostic (2.25e-2)" "prognostic unfavorable (3.86e-5)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.98e-1)" "unprognostic (2.31e-2)" 25.3 29.4 21.9 28.0 28.4 14.6 22.7 30.5 24.9 24.2 20.5 22.2 26.7 20.0 28.1 24.3 22.2 19.2 20.2 20.5 21.9 22.7 20.6 24.5 20.6 30.2 30.9 14.8 24.5 17.1 25.2 35.6 23.8 26.8 19.4 23.9 17.8 17.7 24.1 19.6 20.9 25.8 23.0 28.7 27.0 17.3 22.2 33.6 23.6 19.5 13.8 28.3 24.7 47.9 7.7 10.4 13.5 9.3 9.9 11.5 6.5 22.8 8.2 5.1 8.6 13.4 18.4 4.6 55.9 34.6 21.0 13.6 4.6 10.8 8.0 4.4 62.8 13.1 12.1 5.7 8.3 28.4 5.2 2.8 3.7 13.5 3.5 7.1 4.5 6.6 9.0 9.7 11.2 10.0 26.4 13.0 4.5 3.9 4.1 32.3 9.8 3.2 5.3 3.0 5.3 14.3 4.3 2.1 2.8 9.5 6.5 2.5 2.8 18.2 7.8 7.9 11.1 4.8 5.7 17.7 11.1 6.2 27.2 9.6 2.8 3.3 5.1 20.3 8.7 3.8 13.5 9.3 11.1 8.2 7.9 11.5 7.7 9.1 9.8 10.4 7.5 8.8 9.0 11.7 9.9 7.6 2.7 10.6 6.5 21.9 28.4 30.5 24.9 21.9 22.7 30.9 14.8 26.8 33.6 44.7 27.7 32.0 24.8 44.8 51.3 21.2 12.7 17.4 15.9 17.4 41.2 23.4 6.6 17.2 55.0 28.7 37.8 0.0 10.6 35.6 22.1 32.9 30.0 21.3 20.3 50.9 21.2 31.3 32.9 34.9 24.7 27.8 16.9 16.2 25.6 23.2 28.7 31.6 18.0 18.2 45.2 6.5 25.8 22.4 10.2 53.2 13.0 27.3 17.7 45.1 HIF1AN "DKFZp762F1811, FIH1, FLJ20615, FLJ22027" ENSG00000166135 "Hypoxia inducible factor 1 alpha subunit inhibitor" Q9NWT6 10 100529072-100559998 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048742, HPA065302, CAB069903" Supported Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB069903: AB_10000508, HPA048742: AB_2680507, HPA065302: AB_2685458" "unprognostic (4.07e-2)" "unprognostic (7.75e-2)" "unprognostic (2.35e-2)" "unprognostic (3.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-3)" "unprognostic (1.54e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-2)" "unprognostic (3.09e-2)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (3.24e-2)" 8.8 12.7 11.6 11.9 10.8 7.6 12.9 9.5 14.1 9.2 10.7 11.5 8.8 9.7 11.6 10.4 11.1 9.6 12.5 16.0 10.2 9.4 10.3 8.8 9.3 12.3 13.0 9.5 14.5 14.3 17.1 10.6 10.2 10.8 10.7 9.3 9.2 10.6 12.1 46.8 13.3 10.6 14.9 9.7 11.1 10.0 17.9 10.3 13.5 8.1 14.8 12.3 10.8 10.8 9.7 8.5 16.9 14.0 10.1 11.3 9.3 9.1 9.7 13.1 13.2 20.4 8.5 11.4 9.8 23.7 14.6 17.2 15.0 7.9 9.9 8.9 14.6 10.8 10.7 11.5 8.8 15.9 10.9 7.0 9.4 8.6 11.4 10.6 11.3 12.6 8.3 8.9 14.1 15.5 20.6 8.2 13.3 4.1 5.6 16.3 9.6 12.1 7.4 4.3 7.8 4.7 8.8 16.3 4.8 10.1 12.3 5.0 8.3 8.4 5.2 9.2 11.5 17.8 6.1 6.8 7.5 9.7 7.3 9.8 7.6 7.7 7.6 12.4 9.3 5.5 13.1 8.8 16.9 9.8 12.4 9.6 9.7 10.1 9.0 8.5 7.5 9.8 9.9 9.3 10.1 14.0 3.1 11.3 9.3 11.6 10.8 9.5 14.1 10.2 9.4 13.0 9.5 10.8 10.3 0.0 6.2 14.3 9.8 9.7 16.8 34.6 12.7 4.0 5.7 10.4 15.7 23.3 8.3 15.7 15.4 9.0 14.8 0.0 12.1 15.1 7.1 8.2 5.8 8.7 13.0 23.8 12.7 7.4 17.7 39.0 10.3 10.4 3.3 16.2 11.3 14.3 15.3 14.0 11.3 14.7 21.9 6.5 12.2 39.9 22.2 10.2 27.3 11.7 11.4 8.4 HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929192-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 62.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Nucleoplasm, Cytosol" Centrosome "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" 15.1 16.8 21.2 14.7 23.0 90.1 13.6 38.1 20.4 20.4 14.4 20.7 14.5 10.2 15.5 14.2 18.7 27.3 17.5 27.9 22.9 17.2 14.8 13.8 19.3 14.7 15.0 16.4 18.7 16.8 20.7 23.8 13.8 21.3 14.4 15.2 20.7 13.0 14.9 19.7 18.5 13.4 15.1 18.3 15.9 14.8 33.5 21.3 47.2 23.3 13.1 15.5 17.3 26.7 2.3 6.2 9.8 4.2 4.3 6.0 2.3 8.2 6.7 9.3 7.1 10.9 5.7 6.3 5.7 6.9 8.1 7.8 7.7 3.2 11.1 7.8 9.0 3.0 5.6 12.0 6.6 11.8 8.0 6.0 16.1 8.4 8.1 9.1 12.8 20.0 6.2 9.7 10.4 10.6 7.7 12.0 19.7 11.0 12.0 11.6 62.4 16.8 7.3 9.5 6.2 6.0 10.2 27.3 3.9 7.3 7.1 4.1 5.5 10.4 11.2 7.3 10.8 6.5 18.5 11.6 8.0 10.8 13.0 8.6 7.5 5.8 9.6 9.0 10.4 18.2 3.4 4.2 8.2 5.5 3.7 5.2 1.7 4.9 4.9 3.1 2.3 5.0 6.0 9.8 4.3 2.6 6.2 3.6 2.3 21.2 23.0 38.1 20.4 22.9 17.2 15.0 16.4 21.3 21.3 50.6 37.0 12.9 14.8 54.6 47.6 27.1 22.9 64.3 20.5 26.2 66.8 9.7 5.0 12.5 82.7 29.3 18.8 70.0 18.3 7.9 25.0 26.7 45.1 33.6 19.9 69.9 35.7 23.9 54.6 73.8 20.4 35.5 20.3 15.4 24.2 28.9 17.0 17.3 35.0 13.4 60.3 25.8 37.0 35.4 26.0 70.4 11.9 47.3 22.4 23.0 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.1" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 209.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.8" "Cell line enhanced" "Detected in many" "HDLM-2: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favorable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.6 9.8 58.8 7.4 53.6 14.4 12.6 8.5 39.8 5.5 7.4 54.5 5.2 8.2 4.7 5.2 10.2 9.9 5.5 30.5 60.0 39.9 28.2 17.5 8.6 5.3 66.1 16.4 6.6 12.3 17.2 7.6 10.8 26.4 10.7 5.8 9.4 11.5 7.1 21.6 3.2 6.2 4.8 56.2 7.3 15.4 2.6 38.6 1.7 10.4 2.8 4.9 6.8 7.4 0.6 0.5 17.8 2.9 0.2 1.4 0.5 4.1 18.5 8.6 5.2 21.0 15.1 1.0 2.3 2.3 2.6 2.7 1.3 2.3 0.0 5.3 4.3 16.0 0.2 3.9 6.0 6.5 42.6 1.6 19.0 3.0 6.5 11.8 5.2 5.2 22.9 3.9 11.8 17.8 6.1 6.4 3.6 11.0 5.2 19.8 3.1 6.5 3.7 2.2 2.3 12.7 7.8 4.7 0.5 11.7 0.7 5.2 4.8 5.2 0.1 2.6 1.6 2.9 2.1 21.5 9.1 4.3 10.5 11.3 25.8 15.3 3.7 18.6 2.8 4.9 17.8 1.1 2.7 0.2 0.9 0.3 0.6 0.5 0.1 0.5 0.3 1.4 0.4 1.5 0.2 2.9 0.2 0.0 0.5 58.8 53.6 8.5 25.2 60.0 39.9 66.1 16.4 26.4 38.6 14.9 31.1 34.2 22.5 8.2 100.5 179.2 58.6 29.4 29.6 61.1 143.3 6.0 29.9 26.8 2.4 43.9 23.1 0.0 58.5 1.5 18.6 91.5 42.8 127.8 14.7 209.7 64.5 159.0 115.1 3.1 12.0 28.9 42.2 32.5 35.2 61.0 53.9 17.5 17.7 62.8 59.6 45.3 63.6 0.9 1.7 8.3 8.0 30.2 23.3 40.0 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cardiomyocytes: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 46.3 13.4 12.7 15.9 15.9 12.7 49.2 11.7 13.7 23.6 24.8 11.9 15.9 9.9 28.3 22.8 22.9 24.1 18.8 69.0 13.4 11.8 23.4 21.1 20.2 20.9 15.5 8.2 23.6 15.4 49.7 21.2 20.5 15.2 23.2 12.8 15.6 18.8 18.1 45.9 18.7 25.0 32.9 15.9 20.1 20.5 14.7 14.2 15.2 37.9 26.0 14.4 33.6 34.6 3.1 11.3 17.6 10.1 3.3 4.4 3.7 9.5 9.1 6.9 7.8 32.1 20.3 6.9 10.1 11.8 8.3 7.0 10.0 7.0 10.4 8.6 12.4 4.2 12.3 5.2 11.3 11.7 15.0 8.1 10.4 10.3 7.6 13.3 11.2 6.6 19.0 22.3 3.2 9.3 8.6 10.0 7.6 3.3 20.8 13.3 5.0 9.2 7.8 1.7 8.6 5.5 12.4 24.5 10.3 13.6 15.0 1.0 5.8 13.7 15.8 9.4 7.8 17.8 20.6 12.9 13.0 8.9 14.9 7.2 11.4 17.9 10.9 6.3 11.8 12.1 6.6 10.1 4.8 3.5 7.6 4.4 2.4 3.2 3.7 11.3 3.1 2.9 3.5 17.6 3.3 8.6 1.4 3.2 3.7 12.7 15.9 11.7 13.7 13.4 11.8 15.5 8.2 15.2 14.2 11.9 40.1 19.6 37.7 59.1 15.0 138.1 28.1 60.2 40.9 31.4 17.7 14.6 5.0 10.7 17.4 81.2 34.9 0.0 21.3 10.5 36.9 34.5 13.9 44.7 26.7 30.2 35.6 49.7 100.8 22.3 39.7 52.2 55.6 6.4 26.9 10.8 18.6 21.6 35.3 28.4 23.7 51.8 63.4 10.0 7.6 65.6 12.9 17.3 20.1 42.6 HLTF "HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3" ENSG00000071794 "Helicase like transcription factor" Q14527 3 149030127-149086554 "Enzymes, Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Bipolar cells: 88.3;Spermatocytes: 110.2;Spermatogonia: 89.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015284, HPA049001" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA015284: AB_1857263, HPA049001: AB_2680594" "unprognostic (3.21e-2)" "unprognostic (3.46e-2)" "unprognostic (6.81e-2)" "unprognostic (1.95e-3)" "unprognostic (4.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (3.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.27e-1)" "unprognostic (4.78e-2)" "unprognostic (9.00e-3)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (3.42e-1)" "unprognostic (2.83e-2)" "unprognostic (1.07e-2)" 10.2 22.1 12.6 8.4 17.6 9.0 12.4 29.3 23.8 11.1 11.0 12.4 6.2 4.8 12.4 9.6 7.1 10.8 8.6 16.5 15.8 16.6 15.6 16.3 7.1 9.8 15.7 19.0 17.6 12.0 16.5 25.1 7.3 29.9 14.7 7.0 11.3 9.3 11.1 9.7 5.1 6.6 12.7 19.0 7.5 8.7 37.7 14.0 17.1 19.0 4.8 9.6 10.0 7.8 8.4 9.2 8.8 2.3 5.4 10.4 3.5 24.6 12.0 17.2 13.4 11.5 14.9 1.7 16.7 10.0 12.4 14.5 9.7 17.2 15.9 20.5 7.7 24.3 0.7 23.0 6.6 20.8 8.8 11.2 38.2 9.4 3.9 7.2 10.0 15.9 9.4 3.6 9.2 5.4 19.0 7.1 26.0 13.3 10.4 16.9 12.4 20.5 15.4 12.9 12.5 15.1 23.8 19.3 2.5 10.2 8.0 17.0 10.0 25.4 11.8 23.0 9.5 35.2 9.8 5.0 14.6 8.8 20.5 18.2 15.4 8.6 20.8 14.3 13.7 5.6 8.8 1.3 4.0 5.6 2.1 10.4 8.4 4.9 7.2 3.9 5.4 7.2 7.4 0.2 5.4 2.3 9.2 4.4 3.5 12.6 17.6 29.3 23.8 15.8 16.6 15.7 19.0 29.9 14.0 23.8 14.8 13.8 7.6 4.9 88.3 34.8 17.8 30.8 21.6 29.6 39.3 6.6 29.9 7.9 9.5 10.8 1.3 0.0 7.3 8.2 10.6 11.9 53.2 14.9 7.6 44.5 4.7 15.4 4.0 5.8 31.4 7.5 5.0 3.6 6.2 35.2 6.8 2.8 30.4 15.6 75.2 12.9 14.1 110.2 89.0 3.8 1.4 13.8 6.6 4.3 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873315-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Cholangiocytes: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 10.6;BEWO: 13.0;RH-30: 14.4;SCLC-21H: 11.7;SiHa: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA027295: AB_2672203, HPA027372: AB_2672239" "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 1.7 1.9 2.7 2.9 3.5 0.5 2.1 3.2 6.4 1.1 5.9 0.2 12.6 2.4 9.0 3.4 1.1 3.3 1.0 1.7 3.7 3.2 6.0 1.3 1.7 0.7 1.2 2.1 1.8 15.7 0.2 4.7 7.6 1.4 4.0 6.5 9.1 1.5 11.1 0.6 5.0 4.4 4.1 0.9 0.4 2.1 1.8 0.2 0.4 1.1 2.2 1.0 3.8 7.7 1.0 0.7 1.7 0.5 0.5 0.5 0.1 0.0 3.0 10.6 0.1 0.0 0.0 13.0 1.0 0.0 0.2 0.0 4.2 0.1 0.0 0.4 4.9 0.2 0.1 6.2 0.0 0.0 0.0 3.2 0.0 2.8 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.9 0.2 0.9 8.0 0.0 0.1 0.1 14.4 0.0 1.1 0.0 11.7 7.8 10.3 0.8 0.4 7.7 4.3 1.1 0.0 0.0 7.5 0.0 0.0 0.1 0.0 1.4 0.0 0.0 5.0 0.8 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.3 0.2 1.0 0.5 0.5 1.7 0.5 0.3 0.7 0.4 0.1 2.7 3.5 3.2 6.4 3.7 3.2 1.2 2.1 1.4 0.2 6.0 7.8 0.0 1.8 4.5 4.3 3.2 17.8 1.4 4.5 7.0 2.0 8.1 0.0 3.8 0.0 0.9 2.7 0.0 2.9 11.6 10.6 1.6 0.0 0.9 2.3 3.2 4.7 0.0 0.0 0.0 0.3 0.0 3.3 0.0 3.9 11.4 2.6 2.9 0.0 1.5 1.2 0.0 1.4 0.9 0.7 5.1 5.1 0.0 9.0 0.8 HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase" Q7Z6Z7 X 53532096-53686729 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol NA NA 3400 "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" 24.6 28.2 27.7 23.8 43.3 22.4 28.0 37.0 41.1 31.8 25.9 34.3 26.6 17.1 31.9 52.4 27.4 26.5 23.1 27.1 28.0 31.8 30.3 26.2 20.3 23.1 30.0 30.2 43.3 27.8 59.8 34.2 27.2 34.6 27.3 22.7 25.6 26.4 29.6 59.1 50.1 22.1 33.9 23.9 26.6 25.7 28.4 27.7 32.4 27.6 20.7 28.6 27.0 22.9 5.1 7.2 8.2 7.0 6.9 8.9 3.5 50.2 31.0 20.2 14.2 35.4 21.2 24.9 15.1 19.5 16.0 16.7 23.6 16.2 26.4 10.3 27.5 28.8 24.2 45.6 25.3 21.9 38.0 20.2 21.0 27.8 18.3 32.5 31.4 12.9 20.2 19.0 38.3 44.1 15.8 27.6 20.7 20.9 17.1 20.7 31.0 17.0 17.6 27.6 13.8 22.3 15.7 27.8 16.0 26.5 34.9 16.9 12.2 42.7 19.1 13.6 39.5 27.3 15.3 35.1 14.7 21.1 21.0 19.2 15.0 14.8 23.0 15.7 30.8 21.1 4.0 4.7 8.2 7.2 3.8 8.9 5.1 6.9 7.6 6.7 5.1 4.9 4.9 4.2 6.9 7.0 7.2 5.7 3.5 27.7 43.3 37.0 41.1 28.0 31.8 30.0 30.2 34.6 27.7 47.6 43.2 23.8 25.3 26.8 53.1 98.6 45.9 37.5 36.4 38.4 47.1 26.9 1.7 35.4 22.3 29.2 24.7 0.0 30.4 29.3 24.4 33.4 20.9 43.1 21.9 77.9 45.8 31.3 25.6 21.6 26.2 26.1 25.3 40.5 28.4 20.9 40.0 17.3 36.7 12.2 31.9 12.9 33.0 17.1 43.7 36.4 31.7 37.1 29.2 40.4 HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Distal tubular cells: 24.9;Late spermatids: 27.7;Proximal tubular cells: 33.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 7.1" "Lineage enriched" "Detected in single" 8 "T-cells: 7.1" "Cell line enhanced" "Detected in many" "HEK 293: 17.5;U-266/84: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040706 Approved Approved Vesicles,Aggresome NA NA Vesicles Aggresome "HPA040706: AB_10795528" "unprognostic (9.26e-2)" "unprognostic (1.98e-4)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (2.73e-1)" "unprognostic (5.16e-2)" "unprognostic (6.24e-3)" "unprognostic (6.37e-2)" "unprognostic (3.44e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-3)" "unprognostic (3.90e-2)" 6.3 7.5 6.4 4.8 8.0 1.7 7.7 2.3 6.1 8.2 14.3 2.5 6.8 11.1 6.4 11.0 7.0 6.5 7.5 8.5 4.3 3.5 19.4 10.5 3.6 4.3 3.5 3.6 9.7 15.5 4.0 8.8 1.5 4.3 8.0 6.2 10.1 7.9 10.1 8.9 3.9 21.2 9.4 3.4 1.6 6.8 7.8 2.2 5.7 7.3 3.7 4.1 7.1 5.1 0.4 0.6 0.8 0.2 0.5 7.1 1.2 3.1 5.1 0.5 9.0 2.0 4.4 1.9 1.0 2.1 3.0 3.5 1.7 3.7 2.5 1.1 2.0 5.2 3.6 8.2 2.7 2.8 1.1 17.5 1.1 2.2 4.2 5.1 0.3 1.4 4.0 5.1 1.1 2.3 1.0 2.1 10.7 3.0 6.5 1.7 3.8 2.9 0.5 0.5 7.6 6.5 1.7 9.9 2.0 5.6 3.5 0.9 1.2 2.2 6.7 7.9 1.4 7.6 0.2 0.9 1.9 1.4 3.6 3.3 10.2 17.8 0.1 2.2 0.1 2.7 0.8 0.2 0.5 0.3 0.1 0.4 0.4 2.4 0.4 0.1 0.4 7.1 1.3 0.8 0.5 0.1 0.6 1.0 1.2 6.4 8.0 2.3 6.1 4.3 3.5 3.5 3.6 4.3 2.2 11.9 2.6 0.9 6.2 3.2 2.7 4.4 0.0 4.0 1.2 7.0 2.0 6.0 24.9 1.9 11.0 4.5 2.8 0.0 6.8 3.6 3.6 3.7 0.0 5.0 0.7 0.0 4.1 5.5 0.6 27.7 4.9 0.6 6.8 0.0 3.4 4.8 2.4 3.1 3.5 33.6 1.8 0.0 3.7 3.2 7.5 1.4 2.9 0.0 6.0 3.5 ICK "KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Intestinal cell kinase" Q9UPZ9 6 53001279-53061802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Approved "Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" "HPA000791: AB_2732392, HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 9.8 28.2 10.1 6.5 10.7 2.8 13.4 14.3 12.7 11.5 12.3 20.1 6.6 11.3 10.6 6.8 10.4 9.2 8.3 9.6 10.8 7.7 5.4 9.6 8.2 5.5 13.3 8.1 11.8 8.2 9.0 5.3 44.3 12.3 12.2 13.0 9.7 20.7 12.7 5.9 10.1 14.2 13.7 16.8 6.2 15.0 5.6 12.6 14.8 7.6 7.0 7.9 10.6 9.1 4.5 4.1 6.2 3.1 3.2 5.0 2.1 5.1 1.9 10.1 6.9 6.3 10.0 11.7 4.6 8.5 7.5 8.6 2.7 1.6 3.7 2.8 14.1 2.4 3.4 12.0 4.8 9.9 13.0 4.7 2.8 2.3 14.8 3.2 3.4 3.7 8.8 5.3 3.2 3.7 5.4 6.9 8.2 5.3 15.5 17.0 4.4 3.6 4.2 3.8 18.0 4.2 5.8 4.5 5.0 3.1 3.7 16.3 7.3 4.5 11.2 6.4 10.3 6.5 7.3 5.7 12.0 5.6 4.4 11.4 4.3 3.1 1.5 2.4 3.3 5.8 6.2 3.1 5.6 5.0 2.3 4.8 3.7 3.6 4.1 2.9 4.5 4.2 3.6 1.7 3.2 2.5 4.1 4.8 2.1 10.1 10.7 14.3 12.7 10.8 7.7 13.3 8.1 12.3 12.6 17.9 16.8 7.1 4.3 6.9 30.5 8.7 7.6 17.4 26.1 3.5 35.3 17.7 11.6 8.9 1.8 8.7 9.5 0.0 21.0 27.3 8.2 14.5 19.7 12.3 5.2 25.4 8.6 8.0 10.4 1.1 13.3 6.0 3.3 5.4 25.7 20.1 16.6 2.9 26.9 3.8 41.7 6.5 14.4 6.4 2.7 7.3 48.6 7.5 12.3 8.0 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332653 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.46e-6)" 9.1 10.8 10.9 17.0 16.7 9.3 10.0 26.1 16.9 10.3 10.3 12.4 11.4 4.7 15.3 13.2 17.9 16.4 14.9 7.9 13.1 6.9 12.4 9.9 14.9 12.2 20.3 7.9 9.6 13.3 18.0 13.6 11.2 11.9 14.0 10.9 10.5 11.4 9.7 17.6 22.2 9.8 16.4 10.5 18.7 10.8 8.3 18.6 12.9 14.3 8.4 17.1 18.1 12.8 12.6 14.8 14.1 9.6 11.9 11.2 5.8 3.6 12.9 3.7 6.3 14.3 12.4 4.7 3.2 11.3 9.5 8.4 2.9 6.7 7.1 5.5 8.8 9.0 4.1 5.0 12.7 12.3 6.9 5.7 9.9 6.0 2.3 10.9 1.9 10.4 8.2 9.7 9.1 14.2 18.7 14.0 4.7 8.4 3.5 20.8 4.1 6.9 3.1 3.6 11.8 4.1 7.1 6.3 4.1 10.7 3.3 1.1 2.1 2.0 3.6 5.2 6.9 4.8 8.3 7.2 6.7 3.5 5.2 2.3 2.1 2.1 5.0 7.9 4.7 7.6 14.1 9.6 10.4 10.1 7.6 10.3 9.4 10.5 11.2 8.9 12.6 10.2 10.4 11.4 11.9 9.0 14.8 9.9 5.8 10.9 16.7 26.1 16.9 13.1 6.9 20.3 7.9 11.9 18.6 11.9 24.0 17.7 29.3 21.6 11.3 4.5 15.3 14.7 13.6 15.7 127.6 8.6 1.7 11.4 2.0 27.7 11.8 0.0 11.8 4.6 9.8 23.2 36.9 10.2 15.8 17.5 10.9 15.4 26.9 3.0 15.3 17.7 18.6 13.6 15.1 11.6 13.3 14.4 12.0 4.8 52.3 6.5 6.4 2.6 6.4 25.5 12.7 20.3 13.6 25.7 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 24.8;lymphoid tissue: 19.5" "Cell type enhanced" "Detected in many" 5 "Paneth cells: 20.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 25.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.1 0.9 1.0 17.3 3.4 4.3 1.4 1.1 1.7 2.2 4.8 1.5 1.7 3.9 2.0 3.9 6.1 1.2 3.6 1.1 2.9 1.5 0.6 3.7 13.6 2.1 0.7 1.0 1.5 0.0 0.8 2.5 1.9 1.8 4.3 1.5 8.3 2.9 0.1 8.9 4.2 1.0 2.9 12.8 4.0 0.0 2.4 18.8 2.6 4.4 19.5 4.4 0.4 12.9 4.6 4.2 15.9 10.8 24.8 12.3 9.0 7.1 2.0 0.2 3.6 5.2 2.1 3.6 11.5 5.0 5.6 5.6 14.7 17.9 9.9 7.3 6.0 12.2 0.0 9.3 1.0 2.9 1.7 2.5 4.2 3.9 4.7 15.2 8.1 6.6 1.6 4.1 0.8 5.8 7.2 4.9 1.2 5.5 5.2 1.8 9.7 25.6 2.9 2.1 5.5 5.2 2.1 14.2 5.9 15.4 0.0 0.0 1.6 12.3 2.2 2.6 7.3 10.8 14.0 5.0 3.1 3.6 4.1 1.9 0.9 11.6 9.4 12.8 2.0 4.2 15.9 0.3 10.5 11.2 7.5 12.9 16.7 15.2 4.6 7.4 13.3 13.6 1.1 10.8 6.4 1.5 24.8 12.3 0.0 5.0 8.9 3.6 1.6 0.0 0.8 0.0 2.7 0.0 0.0 0.0 3.5 0.0 10.6 2.7 0.6 10.5 0.0 10.9 3.6 2.4 2.6 4.7 0.8 12.5 0.0 3.5 1.3 11.9 5.2 0.9 5.3 6.8 1.8 6.8 0.0 12.0 20.1 0.7 2.0 0.0 0.0 0.5 0.2 0.5 4.3 1.3 14.4 8.0 9.6 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 130000000 "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 20.9 17.6 11.0 22.3 11.9 7.5 37.0 9.4 14.6 40.2 75.1 14.7 41.9 13.5 75.4 25.2 35.7 33.2 41.1 35.1 11.1 9.2 21.6 15.1 21.9 18.9 11.5 14.0 24.2 22.3 20.4 10.9 22.2 11.5 39.9 24.6 19.3 19.4 89.9 18.5 12.4 22.2 103.5 10.6 20.2 33.2 14.2 11.0 8.2 17.5 14.1 13.6 60.8 25.9 19.5 45.9 76.5 49.4 45.3 25.8 63.7 23.9 18.5 29.2 10.1 45.2 32.1 13.3 35.3 69.8 41.8 51.0 19.3 28.3 9.0 9.4 57.7 41.0 19.3 16.3 29.9 42.0 15.7 14.8 13.0 17.7 15.0 30.3 10.4 14.9 30.8 14.1 28.2 21.6 42.9 39.8 7.8 11.9 10.7 54.5 18.0 9.2 17.8 18.4 20.4 21.8 9.6 15.3 9.6 30.6 19.2 5.1 11.5 16.7 23.1 19.4 29.8 16.1 11.9 46.0 52.5 23.7 21.7 17.1 7.8 4.8 12.7 38.9 15.7 24.4 48.3 49.4 76.5 25.8 47.9 25.1 19.5 23.3 24.4 45.9 17.1 14.7 18.5 31.7 45.3 44.4 18.5 25.7 63.7 11.0 11.9 9.4 14.6 11.1 9.2 11.5 14.0 11.5 11.0 41.7 17.0 28.3 58.4 44.9 13.9 0.3 66.2 18.7 15.9 54.1 7.9 94.6 49.7 120.2 46.5 56.1 64.4 46.7 108.6 153.9 93.0 39.7 29.0 24.9 111.6 7.9 36.5 84.1 50.9 110.9 66.2 80.3 81.0 196.6 43.0 50.2 101.4 57.5 138.6 74.7 29.6 155.2 137.9 31.1 15.7 37.8 92.0 54.3 41.7 41.9 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170401-238203729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA004752: AB_1851753, HPA056099: AB_2797255" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavorable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 17.0 17.1 19.4 31.3 22.2 34.6 24.2 34.1 23.4 18.7 23.4 29.5 22.0 20.5 23.0 22.7 19.4 19.0 21.8 20.9 20.6 19.8 17.8 20.8 27.1 25.7 23.9 21.4 22.1 24.1 17.5 24.7 18.1 22.7 21.5 18.9 20.2 19.0 24.9 32.8 19.4 19.0 26.5 19.8 22.2 18.1 21.2 25.5 23.9 22.6 19.0 24.8 18.1 26.1 18.9 20.7 24.1 18.1 17.4 23.8 16.2 17.9 11.7 17.3 16.9 13.5 9.0 17.7 19.0 12.9 19.3 16.8 10.8 9.6 11.5 4.9 13.7 23.1 15.4 22.3 15.8 19.6 20.5 22.2 29.8 11.6 23.7 20.8 19.0 23.6 9.4 10.9 20.5 20.7 9.5 14.4 15.7 22.9 7.5 16.4 21.6 19.1 25.9 16.1 17.0 11.3 23.4 35.4 10.6 14.2 8.6 25.5 12.6 12.8 13.8 30.4 13.8 10.8 19.8 12.9 18.8 17.2 25.2 20.2 13.4 13.4 20.7 15.4 21.4 15.9 24.1 15.1 19.6 22.5 18.1 20.1 18.9 20.0 21.0 20.7 18.5 23.8 18.6 5.3 17.4 15.1 15.8 22.4 16.2 19.4 22.2 34.1 23.4 20.6 19.8 23.9 21.4 22.7 25.5 11.9 22.4 26.5 25.9 24.0 27.2 20.9 5.1 17.4 13.6 24.4 27.5 31.9 36.5 21.9 7.1 20.3 20.0 23.3 24.8 34.9 21.1 24.0 33.4 14.1 30.1 36.5 18.3 17.2 12.7 9.1 26.2 19.1 28.7 35.1 21.4 23.4 21.2 17.5 27.6 24.2 27.2 32.3 28.0 48.7 60.2 25.1 33.8 27.1 22.5 19.3 IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010500-154019980 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Exocrine glandular cells: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol No No Cytosol Nucleoplasm "CAB004461: AB_2249106, HPA054476: AB_2682501" "unprognostic (4.46e-3)" "unprognostic (9.32e-2)" "unprognostic (1.71e-2)" "unprognostic (5.04e-3)" "unprognostic (7.09e-3)" "unprognostic (4.43e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (7.89e-3)" "unprognostic (3.36e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (2.76e-3)" "unprognostic (2.36e-1)" "unprognostic (2.21e-3)" "unprognostic (3.04e-1)" 22.3 23.7 12.1 25.0 11.4 48.3 38.5 7.7 14.8 11.1 24.8 10.8 13.4 29.9 13.2 12.4 25.5 12.2 23.1 14.1 9.9 12.3 23.7 46.9 18.5 37.5 12.6 7.9 15.1 34.6 8.1 15.2 14.3 11.9 18.0 11.0 10.1 31.9 15.9 32.6 15.9 34.6 11.5 12.7 34.0 19.3 14.3 9.8 17.0 12.6 20.4 26.7 17.2 15.3 10.0 13.0 6.7 10.6 6.3 6.7 3.4 77.0 30.0 4.3 34.6 8.5 6.8 18.5 11.5 10.9 17.8 16.5 23.7 34.2 32.9 64.8 12.3 27.3 21.1 9.8 18.8 6.9 25.8 29.3 12.0 27.0 14.1 19.5 28.3 20.6 9.4 16.5 16.9 18.7 9.2 10.6 6.7 21.1 38.1 12.4 28.4 11.6 25.3 10.5 24.6 59.8 30.2 21.5 55.2 11.8 14.6 23.8 17.2 13.7 15.3 22.7 1.7 5.9 30.2 14.5 21.6 34.2 49.3 71.3 48.0 30.6 60.3 31.5 34.1 22.3 1.3 8.7 6.7 6.7 10.6 5.9 7.5 5.3 5.3 5.4 10.0 3.1 6.1 5.9 6.3 8.1 13.0 2.5 3.4 12.1 11.4 7.7 14.8 9.9 12.3 12.6 7.9 11.9 9.8 0.0 14.1 25.2 11.0 11.8 8.1 8.2 20.4 6.7 19.4 10.4 5.9 9.6 6.6 45.8 0.6 13.7 36.0 0.0 97.4 17.8 12.1 24.0 12.7 32.6 52.7 15.9 19.7 10.4 45.4 1.8 16.7 26.5 13.5 11.8 24.2 14.0 61.0 24.6 20.1 13.3 5.0 0.0 14.5 1.7 6.3 11.4 10.3 14.0 28.8 23.4 IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164865-10243743 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.7" "Cell type enhanced" "Detected in many" 7 "Basal glandular cells: 18.1;Glandular cells: 20.2;Urothelial cells: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 16.2;BJ hTERT+: 16.9;CAPAN-2: 17.1;GAMG: 30.8;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles NA NA Vesicles "CAB013483: , HPA050520: AB_2681154" "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favorable (6.60e-5)" 12.1 5.8 3.6 8.6 5.9 28.7 5.4 4.5 7.0 3.3 4.0 12.2 2.3 3.3 3.5 2.6 8.4 2.4 6.8 2.7 3.6 5.2 4.3 15.4 12.7 5.3 10.4 3.7 1.9 3.2 2.4 1.8 3.5 7.8 6.4 3.1 2.1 4.8 3.4 19.6 6.2 6.7 3.4 6.1 5.9 5.2 1.7 8.6 3.9 4.1 2.7 16.7 14.3 7.2 5.0 1.3 2.5 1.2 8.4 7.9 2.5 1.2 3.7 0.1 0.5 4.0 3.4 16.2 1.3 16.9 2.3 2.2 1.7 17.1 0.0 0.4 2.0 30.8 0.4 0.4 4.3 3.1 1.0 1.2 0.3 0.8 4.7 2.0 0.0 0.5 2.1 0.7 8.5 11.0 6.1 4.7 0.1 0.8 5.2 2.7 0.0 0.0 0.8 0.1 2.0 3.6 0.8 0.0 0.2 5.1 23.4 0.2 0.1 1.6 0.0 0.1 0.4 0.4 0.8 4.8 5.3 0.4 3.2 3.3 1.7 5.1 1.0 11.3 2.2 0.9 0.2 1.2 0.1 7.5 0.7 7.9 5.0 2.2 4.1 1.3 4.5 1.6 3.9 2.5 8.4 0.2 0.1 0.9 2.5 3.6 5.9 4.5 7.0 3.6 5.2 10.4 3.7 7.8 8.6 0.0 5.5 0.9 18.1 7.1 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.1 0.0 8.5 3.3 2.1 1.1 0.0 3.5 0.4 1.0 20.2 0.0 4.7 2.9 0.0 0.0 1.3 2.5 1.1 0.9 4.3 5.0 2.8 0.1 1.7 10.4 0.0 0.0 1.0 0.0 0.0 3.1 0.4 0.4 6.5 0.8 1.5 0.4 22.1 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66188879-66254622 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.0" "Cell type enhanced" "Detected in many" 14 "Ito cells: 36.2;Kupffer cells: 118.3;Macrophages: 66.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 5.6;classical monocyte: 13.1;intermediate monocyte: 13.2;myeloid DC: 6.2;neutrophil: 7.2;non-classical monocyte: 20.6" "Group enriched" "Detected in many" 12 "dendritic cells: 6.2;granulocytes: 7.2;monocytes: 20.6" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 12.4;HEL: 12.8;HL-60: 17.0;NB-4: 13.6;THP-1: 20.6;U-937: 14.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 21.8 3.7 2.1 10.6 3.6 58.0 13.4 1.0 2.4 8.7 6.5 2.3 5.5 1.7 6.2 8.6 4.9 7.0 7.6 16.0 2.9 2.1 3.6 2.9 22.1 25.6 4.6 0.3 5.9 2.7 1.3 17.9 6.1 3.7 7.0 3.0 5.5 6.0 5.5 5.5 3.3 4.9 6.4 5.9 25.3 6.2 5.1 2.8 1.0 4.9 4.5 5.4 9.5 11.4 0.4 6.2 7.2 20.6 0.9 0.3 3.6 0.0 0.0 0.2 0.0 15.0 12.4 0.0 1.6 0.0 0.9 1.3 0.0 1.2 0.0 0.8 3.0 0.0 0.0 1.8 0.0 0.7 0.0 0.0 12.8 0.7 0.0 7.8 17.0 2.4 7.8 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.7 0.0 0.0 0.0 3.7 0.0 0.1 1.9 0.1 0.0 6.7 0.0 0.7 0.0 0.0 20.6 4.7 0.0 0.0 0.0 0.0 0.5 0.1 1.2 0.0 14.9 0.0 5.6 13.1 2.2 0.0 13.2 0.0 0.0 0.0 0.0 6.2 0.4 0.0 0.0 7.2 0.9 20.6 0.0 0.3 3.6 2.1 3.6 1.0 2.4 2.9 2.1 4.6 0.3 3.7 2.8 8.9 20.8 0.8 4.1 1.3 0.3 2.2 0.0 6.7 20.5 3.5 0.0 0.2 0.0 0.6 3.6 29.3 0.0 0.0 1.0 0.1 17.3 1.4 26.5 0.0 8.9 0.0 0.0 36.2 118.3 3.0 6.6 66.9 5.0 2.8 1.0 0.2 2.8 0.0 10.6 0.2 0.0 0.0 7.2 0.7 0.9 1.1 0.2 2.5 0.2 2.2 IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43789543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Approved Nucleoli,Microtubules,Cytosol NA NA Microtubules "Nucleoli, Cytosol" "CAB016685: AB_1618505, CAB022077: " "unprognostic (2.76e-2)" "unprognostic (5.63e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.46e-5)" "unprognostic (6.15e-2)" "unprognostic (3.50e-3)" "unprognostic (1.44e-2)" "unprognostic (8.49e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (4.00e-3)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "prognostic favorable (4.42e-5)" 18.0 9.4 5.1 15.0 10.4 10.3 11.3 3.7 6.0 10.3 12.2 9.1 12.5 10.2 13.0 14.1 15.0 9.4 10.8 7.6 6.7 5.2 13.3 11.8 12.0 24.0 13.2 3.9 9.3 20.1 9.1 16.1 14.0 9.8 10.5 10.0 11.9 11.9 15.1 4.1 15.2 15.0 11.8 13.0 25.0 12.3 7.1 11.7 30.3 17.0 7.7 18.9 11.1 10.7 5.1 5.8 16.9 6.0 8.8 7.7 4.7 5.3 4.0 2.8 3.7 10.2 17.2 4.0 7.6 5.4 6.0 5.5 3.4 5.2 9.2 7.5 6.3 4.0 4.4 3.1 4.9 8.7 13.2 2.9 8.8 3.1 2.1 5.8 12.1 10.8 9.1 7.8 7.6 4.5 10.6 8.9 9.0 8.1 6.9 16.6 2.9 10.5 6.8 1.0 0.0 4.7 7.0 3.4 4.8 4.7 5.1 2.0 2.0 3.7 4.7 3.6 4.0 5.9 10.8 7.9 7.4 1.4 9.1 5.2 8.4 10.9 8.0 7.7 32.7 4.1 16.9 4.6 9.4 7.4 5.4 7.7 4.0 6.1 6.3 4.5 5.1 5.5 5.9 9.3 8.8 6.0 5.8 7.5 4.7 5.1 10.4 3.7 6.0 6.7 5.2 13.2 3.9 9.8 11.7 17.9 17.0 15.7 9.4 9.6 5.7 4.1 22.9 6.7 10.3 31.4 19.6 12.5 18.3 10.9 12.6 12.4 13.8 0.0 15.4 7.3 9.3 8.1 20.9 7.3 15.2 7.9 3.5 12.9 29.8 16.3 11.5 22.9 10.1 18.0 9.3 9.1 12.5 5.8 10.6 11.3 25.0 6.5 8.6 27.0 12.6 10.3 23.3 41.5 7.8 11.2 ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363235-34511393 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles No No Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: AB_1851941, HPA049032: AB_2680607" "unprognostic (2.51e-1)" "unprognostic (6.95e-2)" "unprognostic (1.25e-3)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (3.89e-3)" "unprognostic (1.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (1.30e-1)" "unprognostic (2.24e-1)" "unprognostic (3.23e-2)" "unprognostic (2.21e-1)" 20.7 16.7 18.9 15.4 26.9 20.5 17.5 19.8 26.7 23.9 18.2 37.9 15.2 16.9 18.4 15.1 35.9 14.5 14.5 17.9 20.4 15.9 21.1 46.5 18.5 16.8 29.2 16.5 19.3 17.1 21.6 26.3 26.9 29.0 17.5 20.4 16.7 20.1 18.4 24.0 19.2 20.3 19.8 30.4 17.3 17.3 34.8 32.3 22.3 22.7 13.0 23.6 19.6 21.0 7.3 11.4 19.6 6.2 6.2 11.4 2.7 20.2 13.4 13.7 9.8 15.1 21.6 16.4 16.5 18.9 20.7 20.2 37.6 31.3 9.9 16.0 21.0 28.2 25.7 20.8 33.3 25.2 7.4 6.7 28.8 11.4 22.5 15.8 11.8 13.0 11.0 17.0 17.4 27.4 18.7 15.5 14.4 16.3 17.2 16.1 10.1 17.2 6.2 6.6 12.5 15.9 14.5 28.9 22.9 12.3 35.3 8.4 6.1 30.8 12.1 18.5 14.1 14.5 10.7 15.0 24.7 14.8 16.1 12.2 13.7 14.3 14.5 15.3 7.6 14.4 3.6 5.8 6.1 10.8 6.2 11.4 7.3 3.8 5.7 4.5 6.9 3.3 4.9 19.6 6.2 3.8 11.4 4.8 2.7 18.9 26.9 19.8 26.7 20.4 15.9 29.2 16.5 29.0 32.3 11.9 17.9 13.3 15.9 13.4 19.6 20.1 7.6 28.1 33.0 29.6 23.6 15.1 5.0 11.7 46.0 17.5 21.6 0.0 14.1 17.6 16.0 23.0 18.5 43.1 14.0 14.3 11.5 16.5 22.8 102.3 20.8 21.2 25.3 23.4 15.8 34.3 16.6 21.0 14.5 18.0 26.8 12.9 17.8 25.7 21.5 14.2 39.2 20.6 9.9 38.9 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 71.2;Early spermatids: 45.5;Ito cells: 50.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Cell line enhanced" "Detected in many" "CACO-2: 32.4;HEL: 19.8;OE19: 11.2;SH-SY5Y: 9.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.7 1.4 0.9 1.4 0.6 32.4 2.5 0.1 0.4 3.6 2.2 0.2 0.8 0.0 1.1 0.0 0.3 19.8 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.5 1.6 0.0 4.5 0.1 0.4 2.4 0.0 0.0 2.0 11.2 3.2 1.0 1.6 0.0 0.1 0.3 1.2 9.3 0.4 0.3 0.3 3.6 0.7 0.1 8.2 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 3.0 3.8 0.0 1.4 1.4 71.2 33.4 17.8 8.1 0.0 15.7 5.9 7.3 1.7 4.7 45.5 26.9 30.6 0.0 7.2 0.7 4.8 2.8 3.5 17.4 0.8 0.0 9.2 50.3 2.6 34.6 3.4 0.7 3.3 0.0 12.2 5.4 3.9 20.4 31.1 2.4 2.7 19.4 14.6 1.9 1.7 1.0 11.9 0.7 10.0 1.4 KANSL3 "FLJ10081, KIAA1310, NSL3, Rcd1" ENSG00000114982 "KAT8 regulatory NSL complex subunit 3" Q9P2N6 2 96593170-96642787 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035017, HPA035018" Approved Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA035017: AB_2674414, HPA035018: AB_10601763" "unprognostic (2.19e-1)" "unprognostic (6.94e-2)" "unprognostic (5.62e-2)" "unprognostic (8.72e-3)" "unprognostic (3.28e-1)" "unprognostic (4.35e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (6.34e-2)" "unprognostic (1.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.01e-2)" "unprognostic (2.99e-2)" "unprognostic (2.04e-3)" "unprognostic (3.28e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-3)" "unprognostic (4.99e-3)" 15.3 15.2 8.2 15.4 10.8 15.9 16.9 10.6 13.3 16.6 14.0 13.6 17.8 9.9 21.5 15.3 12.7 17.2 12.1 9.2 7.5 4.8 13.2 9.8 13.7 9.9 10.9 7.3 20.1 17.5 17.0 13.7 12.4 9.6 16.5 9.3 20.2 16.6 19.8 15.7 14.2 15.7 18.0 6.1 15.0 13.4 36.0 8.4 14.8 18.1 10.5 11.0 20.1 14.8 3.6 1.4 4.2 2.6 5.7 5.9 2.8 9.3 5.7 19.1 14.5 8.0 4.3 8.6 7.5 11.9 15.0 16.3 10.6 6.2 13.8 10.9 11.7 11.5 6.1 13.4 7.1 13.0 9.1 10.7 18.9 5.8 11.9 10.7 12.9 7.5 11.0 5.0 10.0 8.5 9.1 8.3 14.8 13.1 9.8 9.3 5.3 23.2 10.3 9.3 4.8 9.7 18.5 13.0 7.5 8.8 9.5 20.4 12.5 8.9 9.8 8.7 11.6 8.5 4.8 12.3 10.4 9.1 7.7 6.7 8.2 5.0 11.6 5.5 14.6 9.6 4.2 2.6 0.8 5.8 2.6 4.3 3.1 3.5 5.9 1.2 3.6 2.6 4.5 0.2 5.7 2.2 1.4 2.5 2.8 8.2 10.8 10.6 13.3 7.5 4.8 10.9 7.3 9.6 8.4 41.7 25.0 4.7 9.1 4.0 14.0 23.7 15.3 12.0 25.0 10.4 41.2 6.6 3.3 8.3 10.9 11.4 10.7 0.0 8.3 3.6 6.6 9.7 17.4 10.6 7.2 14.3 12.6 17.2 8.8 22.8 9.2 8.4 6.8 11.8 16.7 11.4 10.5 5.8 12.0 3.8 29.4 12.9 9.2 23.2 10.5 5.6 9.3 12.5 13.8 9.2 KAT2A "GCN5, GCN5L2, PCAF-b" ENSG00000108773 "Lysine acetyltransferase 2A" Q92830 17 42113108-42121358 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048958 Uncertain NA NA "HPA048958: AB_2680571" "unprognostic (1.71e-1)" "unprognostic (9.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.31e-1)" "unprognostic (3.41e-1)" "unprognostic (9.07e-2)" "unprognostic (1.91e-3)" "unprognostic (3.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "prognostic favorable (3.57e-4)" "unprognostic (2.78e-2)" "prognostic unfavorable (1.41e-8)" "unprognostic (3.97e-2)" "unprognostic (2.90e-1)" "unprognostic (1.89e-1)" "unprognostic (2.29e-3)" 16.9 15.9 30.2 13.6 28.6 8.6 14.0 24.0 42.0 11.2 11.9 10.9 13.1 14.9 13.9 8.9 11.4 14.2 11.8 7.6 27.8 11.5 10.0 11.8 7.2 11.2 27.6 18.0 23.5 16.5 14.8 11.9 10.7 26.0 12.9 9.6 6.0 17.3 14.5 20.1 19.9 13.4 9.7 13.9 15.6 13.0 7.8 29.7 5.3 11.7 6.4 10.4 11.2 21.7 2.0 1.6 0.1 0.4 0.6 2.7 0.8 10.8 21.0 3.1 11.6 4.4 3.6 13.7 7.1 3.8 15.8 7.8 14.2 8.9 21.4 17.9 5.4 11.9 16.3 12.7 11.3 5.6 11.9 26.4 5.3 12.9 12.8 4.6 14.2 14.3 4.3 9.6 8.8 5.6 4.3 6.2 5.4 13.3 4.1 4.2 11.7 33.8 10.4 6.6 27.2 0.0 8.1 6.1 14.1 4.2 11.0 15.0 6.6 7.6 16.7 5.7 2.4 12.3 6.8 4.8 8.0 8.1 11.6 12.6 11.0 10.5 11.9 5.8 12.2 4.4 0.0 0.4 0.0 0.8 0.0 1.7 2.0 1.9 2.4 1.6 1.6 2.7 0.7 0.1 0.6 0.1 0.4 0.3 0.8 30.2 28.6 24.0 42.0 27.8 11.5 27.6 18.0 26.0 29.7 11.9 11.5 13.1 11.2 10.9 14.2 4.7 20.4 4.0 5.7 17.4 9.8 20.4 3.3 7.9 1.0 17.1 3.8 0.0 6.8 15.3 10.1 8.2 11.5 13.7 10.6 9.5 15.1 19.0 8.5 1.3 30.2 7.2 6.8 6.4 8.6 5.8 6.5 5.8 27.3 2.5 7.4 12.9 10.0 4.7 19.6 12.2 9.4 6.4 16.9 7.3 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040023-20154404 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004526: AB_2128417, HPA002470: , HPA055839: AB_2682938, HPA073897: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 10.6 6.6 30.1 9.4 27.5 24.9 6.8 22.0 20.1 10.2 9.4 27.6 7.9 10.9 7.8 5.4 17.3 7.7 8.0 21.9 24.7 18.0 10.8 24.0 10.1 12.7 26.8 15.9 18.2 11.6 38.1 8.7 8.5 24.2 9.5 8.1 10.7 20.9 9.2 33.4 8.9 13.0 8.7 21.4 11.7 9.0 1.8 31.1 8.7 10.0 7.4 12.0 8.7 11.0 2.1 2.7 5.5 1.5 1.1 4.8 0.8 1.5 4.0 2.2 3.6 9.1 8.6 5.2 5.1 7.6 5.4 7.9 1.2 2.6 13.7 2.1 9.6 6.8 1.1 5.5 1.6 4.5 12.4 5.2 12.0 6.3 0.4 4.3 1.8 15.6 3.7 3.0 4.7 3.0 9.5 5.1 3.4 7.7 19.4 7.6 1.9 3.9 3.6 0.9 3.8 3.9 5.1 4.2 2.9 7.3 8.1 1.1 2.4 2.8 4.6 17.3 3.6 4.8 8.1 4.9 9.1 3.7 3.4 5.8 7.4 15.4 3.3 8.3 7.9 19.2 1.3 1.1 2.8 3.6 1.5 3.4 1.0 3.1 2.5 0.9 2.1 1.1 2.1 5.5 1.1 1.1 2.7 4.8 0.8 30.1 27.5 22.0 20.1 24.7 18.0 26.8 15.9 24.2 31.1 29.8 17.3 4.7 10.0 7.6 11.9 56.5 2.5 17.4 14.8 5.2 3.9 5.4 10.0 2.8 2.3 10.5 13.6 23.3 3.8 1.1 9.3 10.0 10.4 26.1 6.5 14.3 11.1 18.4 21.9 1.3 6.1 15.7 16.9 5.4 5.7 12.6 3.7 0.0 4.9 5.3 11.2 6.5 9.9 0.9 0.9 11.3 8.2 13.8 3.1 7.1 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016953 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA016953: AB_1851277" "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favorable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 18.5 19.5 21.2 16.0 27.4 34.3 21.6 29.4 37.1 22.1 24.1 28.2 22.3 16.5 30.1 24.8 21.2 32.9 24.5 21.1 18.3 19.2 22.6 16.1 20.8 18.3 19.0 25.7 29.5 23.2 38.8 22.0 32.7 24.6 21.2 19.4 29.3 23.6 27.5 24.6 27.6 19.2 25.2 20.1 22.0 21.9 30.7 22.8 26.9 26.5 19.1 22.1 24.4 22.0 25.0 24.0 40.4 23.6 24.8 28.6 23.3 19.1 23.4 21.3 16.2 16.9 17.9 22.4 13.9 22.7 23.3 20.3 17.0 22.9 17.6 19.9 24.3 25.7 16.2 26.5 23.3 14.1 22.9 17.0 25.8 19.3 20.1 24.3 28.1 31.0 19.0 26.1 15.3 31.5 18.0 14.6 20.7 26.6 27.6 22.0 34.9 23.8 32.9 18.6 13.7 15.1 19.6 14.1 32.2 21.3 29.1 19.9 21.0 13.2 25.0 26.5 11.6 24.5 18.2 18.7 18.9 16.7 14.9 14.9 21.2 21.8 25.9 16.3 13.8 15.4 23.4 23.6 40.4 25.7 22.3 22.1 21.1 22.5 25.5 24.0 25.0 28.6 23.3 26.1 24.8 23.3 14.5 21.5 23.3 21.2 27.4 29.4 37.1 18.3 19.2 19.0 25.7 24.6 22.8 11.9 13.7 18.8 38.6 18.8 41.0 0.6 17.8 24.1 14.8 27.9 29.5 43.8 29.9 35.7 7.2 16.8 22.2 0.0 44.9 35.8 24.2 20.6 33.4 9.3 32.0 36.5 29.1 16.5 14.9 9.4 25.9 18.3 40.5 53.3 18.0 36.1 31.7 25.9 36.4 25.6 34.3 45.3 33.0 35.4 22.7 18.6 85.7 25.5 24.7 24.6 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051990 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 20.8 10.9 15.3 19.8 20.3 36.8 22.6 29.9 18.7 19.7 14.6 19.4 14.4 10.7 20.6 12.1 16.9 16.5 14.3 13.0 15.5 11.5 12.3 13.6 26.9 28.2 23.2 10.3 27.2 13.1 26.8 22.3 20.9 15.7 14.1 12.0 12.8 15.1 17.0 21.0 25.5 18.0 25.0 22.9 20.4 14.0 14.1 21.7 30.4 17.9 14.3 20.1 16.9 24.2 4.7 1.8 10.9 1.6 3.1 3.9 1.4 13.1 10.8 17.8 11.3 10.0 11.4 6.0 8.8 11.5 10.9 8.5 6.8 6.3 19.5 8.9 8.7 10.6 8.5 13.8 8.4 13.0 10.0 8.1 28.1 6.7 5.1 7.5 14.8 12.9 9.5 9.6 10.1 12.6 8.0 10.5 17.3 23.5 12.4 10.0 5.8 30.0 4.7 6.8 9.9 4.3 24.0 19.9 6.2 5.4 15.1 11.1 9.5 10.3 6.9 7.1 8.4 15.9 6.5 12.2 13.5 9.6 12.0 9.4 10.1 16.4 21.2 7.3 6.7 11.6 3.5 1.6 2.8 3.5 1.2 3.9 2.4 2.6 3.3 1.0 4.7 3.6 2.9 10.9 3.1 1.2 1.8 3.5 1.4 15.3 20.3 29.9 18.7 15.5 11.5 23.2 10.3 15.7 21.7 32.8 30.4 27.2 23.8 44.8 44.6 22.6 25.5 21.4 30.7 12.2 51.1 12.1 3.3 11.8 1.8 50.4 18.7 46.7 10.4 13.1 28.5 21.6 33.6 22.2 14.6 55.6 23.7 43.0 37.4 3.5 26.2 31.3 21.9 8.2 25.7 32.4 13.2 17.5 21.5 9.3 45.4 19.4 33.9 41.9 36.2 53.4 17.6 45.8 18.9 26.1 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74825582-75032622 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favorable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 11.6 9.5 11.1 13.2 11.9 15.1 12.4 19.0 11.6 16.7 12.2 13.3 15.3 7.2 25.1 13.0 12.0 13.2 12.0 10.0 10.6 9.5 9.0 7.3 9.2 9.0 9.0 9.9 24.6 13.3 24.8 31.1 9.4 8.9 13.5 9.6 10.1 17.9 12.0 15.3 10.6 11.3 16.2 9.3 10.4 13.0 12.8 12.1 26.6 13.0 8.9 12.5 14.3 12.7 3.2 1.9 1.6 1.1 5.3 3.7 1.5 3.9 4.1 7.4 6.3 5.9 8.7 3.6 3.5 7.0 3.0 3.4 2.7 4.6 8.5 1.9 6.4 3.2 3.1 3.9 3.1 5.0 3.6 5.7 3.1 3.3 3.9 4.4 7.4 2.1 5.6 5.0 4.2 6.7 9.9 3.5 6.7 3.3 7.3 3.8 4.3 7.1 3.4 4.1 4.3 22.9 11.1 3.8 1.8 2.2 2.0 3.7 6.2 3.6 6.6 3.2 2.8 3.7 2.9 4.2 4.3 5.1 2.8 3.3 5.4 6.3 5.7 4.6 7.8 0.9 0.7 1.1 1.6 3.2 0.9 3.4 2.4 2.4 2.7 1.2 3.2 3.7 3.4 0.9 5.3 0.8 1.9 2.4 1.5 11.1 11.9 19.0 11.6 10.6 9.5 9.0 9.9 8.9 12.1 41.7 50.1 23.2 20.4 17.6 50.8 43.1 10.2 38.8 35.2 8.7 64.8 8.7 8.3 8.6 4.4 18.6 17.3 23.3 15.8 8.8 28.2 22.8 39.4 14.4 9.7 41.3 22.8 13.5 11.0 6.7 39.1 13.9 13.5 4.6 18.3 49.8 10.2 14.4 37.8 8.0 53.6 25.8 24.0 25.6 21.2 15.3 19.0 34.6 15.5 17.1 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788555-49835030 "Enzymes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 15.8 14.3 16.9 16.2 25.9 44.4 17.5 37.0 35.0 19.5 17.3 23.8 17.9 13.1 27.3 18.6 18.8 19.5 14.6 25.3 16.8 21.8 18.7 11.3 13.9 15.3 17.0 23.6 21.9 13.6 44.4 19.8 19.8 21.9 20.4 14.9 20.8 18.9 23.3 31.7 22.7 14.7 21.8 17.9 15.8 15.5 63.7 19.1 25.9 28.6 14.5 20.6 22.7 17.4 13.0 12.7 15.2 11.4 20.6 20.7 14.2 13.0 18.3 17.8 12.4 8.4 11.1 21.5 11.3 13.2 20.4 14.6 28.3 9.3 14.9 18.4 12.0 17.8 11.4 16.9 11.8 24.1 16.2 16.7 17.7 13.3 11.7 12.5 18.1 14.8 10.6 11.9 18.3 22.9 11.8 15.0 16.6 19.6 14.9 19.1 19.8 25.7 13.0 44.1 27.9 16.0 16.2 28.4 12.9 9.5 14.7 19.3 16.4 11.6 6.9 10.6 28.1 25.5 16.0 9.0 25.9 14.0 11.3 14.7 21.8 23.8 17.5 11.7 10.9 16.1 15.2 11.0 15.1 16.9 8.9 20.7 13.0 16.3 17.1 12.7 12.2 20.6 16.2 13.1 20.6 11.4 6.6 14.3 14.2 16.9 25.9 37.0 35.0 16.8 21.8 17.0 23.6 21.9 19.1 23.8 17.6 14.7 9.0 14.9 30.8 23.6 20.4 24.1 20.5 26.2 29.5 18.8 8.3 9.4 17.4 18.6 10.4 0.0 6.5 13.0 11.4 13.2 23.1 9.0 11.5 42.9 24.1 12.3 16.1 11.0 15.5 11.1 13.5 12.6 12.1 15.3 8.2 8.6 17.3 8.7 25.3 38.8 13.9 69.0 33.2 17.6 28.3 20.2 11.4 7.2 KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31115754-31131393 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Late spermatids: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 17.8;neutrophil: 17.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm NA NA Nucleoplasm "HPA066324: AB_2685658" "unprognostic (8.58e-2)" "unprognostic (9.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (3.22e-1)" "prognostic favorable (6.34e-4)" "unprognostic (3.13e-2)" "unprognostic (3.05e-1)" "unprognostic (5.50e-2)" "unprognostic (9.77e-2)" "unprognostic (7.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.29e-1)" "unprognostic (5.00e-1)" "unprognostic (1.41e-1)" 18.4 21.7 22.7 29.4 23.6 26.6 29.7 48.9 30.8 28.0 24.8 18.3 27.5 15.7 29.8 48.3 16.7 35.0 28.2 32.7 23.0 21.2 20.8 18.9 26.3 29.0 20.2 21.0 52.8 31.4 38.0 22.2 31.5 16.8 21.2 17.7 22.1 35.1 26.2 39.8 22.1 19.7 25.9 20.5 27.4 18.6 27.3 18.4 30.2 31.7 22.6 22.2 20.2 26.6 2.1 4.1 17.8 4.6 1.7 2.9 1.9 7.7 12.0 15.0 4.5 17.8 13.4 15.4 6.9 13.3 11.2 12.3 6.0 17.0 18.3 11.0 8.6 10.2 9.3 23.9 11.6 11.1 15.3 16.2 7.9 8.8 19.0 16.0 13.1 14.4 12.6 23.4 8.3 24.2 14.7 10.6 19.4 21.1 15.1 5.7 22.6 20.2 24.8 16.9 18.8 7.3 32.6 12.3 21.5 9.0 4.6 15.8 16.1 4.2 11.7 5.8 9.6 12.7 21.8 6.3 4.7 10.1 5.3 5.0 14.4 14.5 10.4 7.2 17.5 7.1 3.9 4.4 17.8 1.9 2.4 2.4 2.1 2.2 2.6 4.1 1.8 2.9 2.1 17.4 1.7 4.6 1.4 1.3 1.9 22.7 23.6 48.9 30.8 23.0 21.2 20.2 21.0 16.8 18.4 17.9 15.6 17.9 35.9 18.4 17.8 15.2 12.7 4.0 14.8 8.7 13.7 25.5 18.3 19.6 99.8 18.5 18.6 23.3 23.2 17.7 24.7 25.4 27.6 11.1 26.6 30.2 23.6 16.5 29.2 102.1 49.8 22.4 23.6 22.6 19.7 36.9 14.8 17.5 50.9 12.4 23.7 25.8 17.5 30.4 18.8 13.7 38.0 20.0 20.7 22.1 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819148-50823787 "Enzymes, FDA approved drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "pancreas: 742.6;salivary gland: 473.0" "Cell type enhanced" "Detected in many" 19 "Exocrine glandular cells: 663.7;Mucus-secreting cells: 890.7;Pancreatic endocrine cells: 205.3" "Group enriched" "Detected in many" 6 "colorectal cancer: 20.0;pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 10.9;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 14 "B-cells: 10.9" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 29.2" "Secreted to digestive system" NA NA 4300000 "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.2 2.5 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.8 0.1 0.1 0.1 0.1 0.1 0.1 742.6 0.0 0.1 0.1 0.1 0.2 1.9 0.1 473.0 0.1 0.1 1.8 0.6 0.1 0.1 0.3 0.1 0.1 0.1 0.1 1.2 0.2 0.2 0.1 0.1 10.9 0.7 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 0.3 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 10.9 0.0 0.0 0.2 3.8 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.1 17.9 1.4 17.3 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 38.1 2.8 0.4 0.1 46.5 0.0 663.7 0.0 1.6 15.7 9.2 0.0 0.6 0.0 112.7 0.0 0.8 0.0 5.8 2.9 5.0 9.0 890.7 0.0 205.3 113.2 0.0 0.2 0.0 0.0 0.1 0.3 0.7 47.2 0.0 0.0 128.7 3.4 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "prostate: 163.5" "Cell type enriched" "Detected in some" 36 "Glandular cells: 729.8" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 5.0;NB-4: 10.2" HPA000764 Supported "Secreted in male reproductive system" NA NA "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.0 0.1 0.0 0.1 0.0 1.1 0.2 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.5 0.0 0.1 2.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.2 0.0 2.2 1.9 5.7 2.2 1.6 1.3 0.5 1.7 1.1 0.6 1.6 0.0 0.9 5.0 0.5 0.3 0.2 0.2 0.6 0.8 1.8 0.2 0.0 0.8 2.0 0.2 0.0 0.3 1.7 1.1 0.0 1.3 0.4 0.0 0.3 3.1 0.5 0.3 0.3 0.4 0.5 0.0 1.1 1.5 2.0 0.3 1.8 1.2 10.2 1.1 1.7 0.0 0.9 0.0 2.9 0.0 1.7 0.9 1.6 0.3 1.4 1.3 0.2 1.3 0.4 0.8 1.3 1.9 4.9 1.7 1.8 3.2 0.8 1.9 1.7 1.4 0.9 2.2 1.6 1.2 1.0 1.0 1.0 0.8 1.0 0.5 2.2 0.8 1.3 5.7 1.6 0.8 1.9 0.4 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 13.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 729.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 5.0 0.6 0.0 0.0 0.0 9.2 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718256 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved NA NA "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 15.4 12.9 17.6 12.5 17.6 19.4 14.7 38.4 16.9 15.9 13.6 17.4 9.5 10.1 17.7 11.8 12.2 14.6 11.1 11.7 15.1 8.8 11.5 11.1 12.7 12.6 18.2 8.8 23.6 12.2 22.3 21.8 17.2 15.5 16.3 12.5 14.1 13.8 11.9 12.4 12.8 14.7 15.8 13.0 13.5 11.6 10.6 19.6 20.5 12.9 6.5 12.8 14.7 14.7 7.4 4.6 9.5 11.4 4.2 8.9 2.9 6.1 4.9 10.3 14.6 9.8 12.8 7.9 8.2 8.3 8.9 8.9 7.9 5.4 10.0 8.4 11.5 7.0 8.7 13.5 8.8 14.1 9.3 10.8 20.3 6.2 7.1 9.1 19.0 14.8 8.5 14.2 10.1 17.3 9.0 11.0 8.8 24.9 10.3 8.7 7.4 9.8 7.8 6.1 5.7 4.8 9.6 12.4 4.7 8.2 8.8 6.9 11.0 11.6 8.5 6.1 7.2 8.7 16.4 13.6 7.1 11.2 8.4 13.2 8.6 9.5 11.6 6.5 10.7 10.4 9.5 4.2 6.6 8.9 7.7 8.0 5.8 7.0 7.4 4.6 7.4 6.0 7.8 2.9 4.2 11.4 4.1 6.7 2.9 17.6 17.6 38.4 16.9 15.1 8.8 18.2 8.8 15.5 19.6 11.9 17.6 9.0 9.7 14.4 19.3 8.9 17.8 13.4 13.6 7.0 17.7 8.2 1.7 7.3 18.1 13.1 11.6 0.0 5.7 9.8 11.4 13.8 13.9 12.2 9.5 12.7 16.1 20.9 12.6 5.2 12.7 11.0 13.5 5.4 12.3 10.4 8.1 11.5 24.4 5.0 21.0 19.4 10.5 7.1 8.7 15.7 11.0 13.6 11.1 11.2 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973032-21061547 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" NA NA "Centriolar satellite, Cytosol" "HPA039191: AB_2676385, HPA049037: AB_2680609" "unprognostic (2.77e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 22.9 13.0 3.0 8.6 5.7 12.8 33.0 7.9 3.7 16.6 14.0 6.8 9.3 2.9 21.2 12.7 15.1 11.0 20.6 14.1 5.4 2.6 12.4 11.0 19.8 10.9 5.2 2.4 17.4 10.2 5.0 3.5 18.3 6.3 13.7 4.5 16.7 8.0 11.1 23.0 9.3 7.4 34.6 7.5 15.2 10.4 27.8 5.2 1.4 17.2 13.8 7.0 20.3 28.0 0.1 1.5 3.3 1.9 1.3 3.1 0.5 3.4 3.8 8.5 5.1 10.0 13.2 7.8 11.4 11.9 12.0 10.3 10.8 5.2 0.0 5.6 17.4 4.7 5.0 5.0 5.2 17.8 1.9 1.3 6.3 4.8 8.1 15.5 1.7 2.2 19.5 9.6 7.9 5.3 6.0 16.7 1.4 1.1 0.2 15.1 5.9 0.2 5.9 2.0 3.5 1.8 1.5 15.1 0.0 8.5 1.6 0.1 0.0 9.0 6.0 11.9 7.7 5.1 3.2 21.0 12.8 8.5 9.3 7.2 1.5 0.8 0.0 3.0 1.9 9.7 0.4 1.9 1.8 1.6 1.5 3.1 0.1 0.2 0.5 1.5 0.0 0.1 0.3 3.3 1.3 0.6 0.1 0.0 0.5 3.0 5.7 7.9 3.7 5.4 2.6 5.2 2.4 6.3 5.2 38.7 6.9 2.4 13.7 29.2 0.0 20.6 15.3 12.0 11.4 5.2 0.0 18.7 3.3 8.7 94.1 30.9 3.2 0.0 6.4 7.9 22.8 18.0 4.7 14.5 9.0 0.0 0.0 43.0 13.7 6.2 23.6 16.6 16.9 0.0 1.6 4.5 14.9 1.7 32.5 6.4 0.7 6.5 25.9 6.7 13.7 22.1 40.2 4.4 1.0 9.4 LCT ENSG00000115850 Lactase P09848 2 135787840-135837180 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "intestine: 255.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Group enriched" "Detected in some" 4 "JURKAT: 3.6;MOLT-4: 6.9;RPMI-8226: 13.7" "Region enriched" "Detected in single" 16 "hippocampal formation: 17.3" NA NA "unprognostic (2.21e-2)" "unprognostic (1.65e-4)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (8.03e-4)" "unprognostic (3.55e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (1.64e-4)" "unprognostic (4.90e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (1.02e-1)" 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 209.8 0.0 0.0 67.7 0.1 0.0 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 255.5 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.7 0.0 0.0 6.9 1.1 0.0 0.0 0.0 1.6 0.0 13.7 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.1 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.2" "Cell type enhanced" "Detected in many" 6 "B-cells: 22.9;Hofbauer cells: 25.0;Horizontal cells: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 8.8 8.6 31.6 18.2 18.6 6.3 7.4 14.3 44.1 11.5 6.6 7.1 6.6 6.9 7.3 5.3 6.4 6.0 10.8 6.3 26.8 32.9 5.2 2.6 12.5 22.0 33.4 22.2 12.1 8.1 4.0 7.2 8.0 45.2 6.1 4.7 4.8 18.1 9.6 10.9 6.8 7.2 7.6 10.8 18.4 7.8 10.4 6.5 4.3 7.5 3.7 18.1 14.1 7.2 4.6 8.6 3.8 7.7 6.9 2.4 3.1 17.0 13.3 10.2 16.9 13.5 18.3 7.4 10.6 10.2 8.6 9.6 7.7 16.9 10.6 4.8 13.0 28.9 10.3 3.8 6.5 3.3 18.3 6.7 7.8 4.5 8.8 15.5 5.9 28.7 18.1 5.9 6.9 3.6 26.0 12.8 7.7 5.2 3.4 10.7 14.9 5.1 10.7 19.3 6.0 8.4 7.4 15.8 6.6 9.6 3.7 4.0 9.3 6.8 16.4 8.5 11.7 5.2 5.4 15.2 13.7 12.8 35.4 17.0 3.8 4.3 19.4 50.9 4.3 9.3 0.1 6.5 3.8 2.4 7.7 1.8 4.6 0.6 1.5 8.6 2.4 0.2 0.7 0.7 6.9 4.7 0.8 0.4 3.1 31.6 18.6 14.3 44.1 26.8 32.9 33.4 22.2 45.2 6.5 3.0 2.4 22.9 4.6 2.6 5.6 2.7 7.6 2.7 3.4 1.8 2.0 2.2 0.0 6.6 0.6 3.0 0.9 0.0 5.6 5.4 7.5 5.1 5.7 1.1 25.0 33.4 2.4 2.5 10.7 1.5 6.6 14.1 3.3 10.0 2.1 3.1 10.2 2.9 5.6 1.5 3.1 0.0 2.1 1.9 12.4 2.8 3.1 10.1 2.5 6.2 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 14.7;neutrophil: 37.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 37.2" "Cell line enhanced" "Detected in all" "BEWO: 37.6;hTCEpi: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 9.4 6.6 23.5 23.6 26.2 29.4 17.0 9.9 16.8 11.0 20.9 15.6 10.7 13.1 12.9 8.7 33.7 22.1 28.7 6.0 15.4 10.7 15.4 19.9 21.6 18.1 20.8 7.2 11.4 19.9 20.0 12.8 64.3 23.3 17.1 22.1 10.1 25.7 16.2 9.7 36.7 13.3 10.1 28.3 17.4 18.5 16.8 17.9 12.4 25.8 15.6 15.3 13.1 20.0 1.0 1.6 37.2 1.9 2.4 5.6 1.6 7.0 1.1 4.9 2.7 2.1 2.5 37.6 4.6 2.2 4.7 4.0 6.0 3.3 6.9 8.3 7.0 2.2 14.3 5.7 24.5 2.9 5.0 6.2 5.0 5.5 6.5 3.2 9.2 9.2 4.0 69.7 3.8 11.5 32.0 11.9 5.6 2.7 5.0 6.4 5.5 5.6 3.1 4.6 18.2 1.8 7.4 8.3 3.8 5.4 16.7 6.3 5.6 3.5 22.6 9.3 15.9 18.8 3.7 7.2 4.2 6.6 2.3 4.3 2.8 4.1 6.0 2.6 4.3 1.8 2.1 1.9 14.7 1.3 1.3 2.4 0.8 2.3 1.7 0.7 1.0 2.3 1.8 37.2 2.4 0.5 1.6 5.6 1.6 23.5 26.2 9.9 16.8 15.4 10.7 20.8 7.2 23.3 17.9 29.8 17.0 3.0 42.2 31.9 7.0 19.8 12.7 33.5 28.4 5.2 19.6 59.9 3.3 10.9 1.0 19.3 16.9 0.0 38.9 46.0 10.8 19.1 23.1 6.8 15.7 3.2 12.7 12.9 7.9 1.3 4.0 11.8 3.3 2.8 41.8 15.6 22.5 10.5 4.2 8.1 23.2 19.4 4.1 9.8 10.4 34.3 96.6 8.7 49.0 20.7 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 13 "Early spermatids: 34.9;Fibroblasts: 69.8;Peritubular cells: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 105.1;fHDF/TERT166: 160.3;HSkMC: 39.1;hTERT-RPE1: 42.3;U-138 MG: 53.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 290000 "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 33.8 1.8 1.0 7.2 1.2 0.0 37.4 0.9 0.9 16.1 11.7 0.1 4.1 3.8 6.3 20.1 11.1 7.6 12.8 21.4 1.2 1.3 6.5 2.4 20.6 4.3 0.9 1.1 15.7 6.0 0.8 1.5 14.8 1.6 11.2 3.0 3.2 3.4 3.5 12.7 11.3 4.5 9.5 1.5 7.7 4.0 10.6 0.1 0.7 10.8 4.2 2.7 36.9 10.4 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.1 0.0 0.3 0.1 18.3 21.6 0.0 105.1 22.1 8.1 28.7 0.1 0.0 0.0 2.5 160.3 0.4 0.0 0.4 0.2 17.4 0.0 0.3 0.0 2.1 0.8 23.1 0.0 0.0 39.1 0.4 13.5 0.6 42.3 10.1 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.8 0.0 0.4 0.0 0.0 0.5 7.4 0.0 0.7 3.4 0.0 0.0 0.8 53.3 3.6 31.5 1.4 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.0 1.2 0.9 0.9 1.2 1.3 0.9 1.1 1.6 0.1 8.9 0.6 0.0 1.6 6.9 0.6 1.2 0.0 4.0 1.2 0.0 0.0 0.7 0.0 7.1 34.9 3.3 0.0 0.0 0.5 17.3 69.8 1.8 0.0 0.4 1.9 1.6 0.0 14.1 1.5 2.4 13.0 0.3 5.0 1.0 0.0 0.0 1.4 0.0 36.7 0.0 1.1 19.4 8.2 0.5 0.0 9.4 4.0 0.0 0.0 0.7 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23297189-23425328 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 15.5;Extravillous trophoblasts: 20.1;Fibroblasts: 16.6;Ito cells: 23.4;Sertoli cells: 25.8;Smooth muscle cells: 22.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 8 "pons and medulla: 22.7" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 109.9;BJ hTERT+ SV40 Large T+ RasG12V: 63.6;fHDF/TERT166: 71.2;TIME: 59.3;U-87 MG: 110.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 37.8 2.7 1.2 14.5 1.6 0.6 22.4 2.9 1.6 16.9 18.4 1.0 12.2 5.8 11.8 9.1 11.5 4.1 5.4 7.2 1.2 1.3 4.3 4.1 6.2 7.5 1.9 0.7 15.6 4.4 1.3 2.2 38.0 22.7 8.4 3.8 1.6 5.6 9.7 6.2 4.3 10.7 27.3 10.9 8.3 7.7 4.1 0.7 1.6 4.3 8.0 8.6 19.1 6.4 1.9 1.3 3.0 0.7 2.1 2.8 0.7 6.3 17.0 5.1 4.1 14.0 23.1 2.2 109.9 35.6 50.4 63.6 0.1 0.4 1.2 0.8 71.2 23.4 5.3 0.2 9.4 26.7 0.2 0.9 0.0 2.3 0.1 28.3 0.0 0.4 20.4 0.4 18.8 2.5 33.6 42.1 0.2 0.0 0.2 16.6 3.4 0.0 0.1 3.3 0.0 2.6 0.2 4.2 0.0 14.6 0.0 0.1 1.4 13.7 0.7 1.0 16.8 0.1 0.1 59.3 46.9 12.4 19.1 14.4 0.4 0.0 3.3 110.2 0.1 48.8 1.9 0.7 3.0 1.6 0.3 0.8 1.9 0.6 1.3 0.5 0.9 0.8 2.8 1.6 2.1 0.6 1.3 0.2 0.7 1.2 1.6 2.9 1.0 1.2 1.3 1.9 0.7 22.7 0.7 0.0 4.0 0.5 0.4 2.3 1.7 1.7 0.0 1.4 0.0 0.0 0.0 2.0 0.0 1.5 0.5 15.5 0.0 0.0 1.3 20.1 16.6 0.5 0.0 0.0 1.1 1.6 0.0 23.4 0.3 0.0 0.9 0.5 3.3 0.0 0.0 0.8 3.4 0.0 0.4 0.0 3.1 25.8 22.6 0.9 0.9 2.8 0.8 0.0 0.0 0.1 LRRK1 "FLJ23119, KIAA1790, RIPK6, Roco1" ENSG00000154237 "Leucine rich repeat kinase 1" Q38SD2 15 100919215-101078254 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.3" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 30.0;monocytes: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.2;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 23.5;Karpas-707: 17.3;U-266/84: 15.6;U-698: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010537 Uncertain Supported Mitochondria,Cytosol NA NA "Mitochondria, Cytosol" "HPA010537: AB_1079283" "unprognostic (3.74e-2)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-1)" "unprognostic (6.68e-2)" "unprognostic (6.35e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (3.43e-2)" "unprognostic (3.34e-2)" "unprognostic (2.95e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-2)" "unprognostic (3.13e-1)" "unprognostic (5.25e-2)" 6.1 1.9 4.5 26.3 3.9 6.5 5.0 2.1 8.1 6.4 8.0 5.9 2.2 2.9 7.9 6.0 5.4 7.1 4.2 3.4 4.0 1.5 2.7 1.0 4.7 15.0 4.5 4.0 6.3 5.3 2.8 2.3 4.4 2.5 7.1 6.5 2.8 7.7 6.8 1.6 7.3 8.5 5.7 3.7 11.1 3.9 5.1 3.4 1.2 3.5 2.1 17.4 7.5 6.7 2.3 3.3 3.2 1.1 0.0 0.0 0.1 0.8 4.8 0.0 0.0 7.4 7.6 0.0 2.9 2.1 2.7 1.9 0.8 2.1 23.5 1.1 7.8 0.0 4.8 0.7 0.5 1.4 0.4 1.1 7.1 1.1 0.0 0.5 3.8 5.5 6.0 1.0 1.7 1.5 0.7 4.7 0.0 1.2 17.3 0.5 0.0 0.0 2.4 0.2 4.3 2.0 1.7 0.4 6.4 0.0 0.0 0.0 1.7 1.8 2.7 5.4 0.0 0.3 4.6 5.4 0.0 0.8 1.0 0.0 8.8 15.6 15.2 0.3 0.5 4.4 0.0 0.7 3.2 0.0 0.3 0.0 2.3 0.0 0.0 0.9 1.5 0.0 0.0 0.8 0.0 1.1 3.3 0.0 0.1 4.5 3.9 2.1 8.1 4.0 1.5 4.5 4.0 2.5 3.4 14.9 12.8 11.9 6.5 2.9 0.6 2.8 2.5 8.1 7.9 0.0 5.9 8.4 0.0 3.6 3.0 5.7 12.0 0.0 2.7 3.1 3.5 6.3 1.1 0.0 9.5 0.0 13.2 12.3 14.3 2.4 30.0 14.0 3.3 32.5 12.8 0.8 6.7 10.5 20.1 0.3 0.4 6.5 2.1 5.2 1.1 3.0 3.0 0.5 10.8 9.3 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 40.4;lung: 50.4" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 2: 391.0" "Group enriched" "Detected in many" 7 "lung cancer: 5.3;renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Cell line enhanced" "Detected in some" "A549: 9.9;ASC TERT1: 10.2;BJ hTERT+: 5.7;RPTEC TERT1: 10.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 3.7 3.4 2.3 7.0 3.9 8.6 3.0 1.7 5.0 5.1 4.5 1.7 2.6 0.7 5.3 2.9 5.3 3.8 4.5 4.0 1.8 1.4 10.6 4.5 50.4 6.8 2.2 3.6 5.8 3.3 10.9 2.5 1.0 1.9 3.6 1.6 3.3 4.2 2.0 5.6 2.6 3.4 6.7 4.9 8.6 2.7 1.2 2.4 0.5 3.9 2.7 4.9 4.6 6.8 0.9 1.5 40.4 5.8 0.0 0.0 0.8 0.0 9.9 0.1 0.0 3.9 10.2 0.1 2.1 5.7 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.3 0.0 0.3 0.0 0.4 0.0 0.8 0.3 0.2 0.0 0.7 0.5 0.1 2.5 0.7 0.0 0.2 3.8 0.6 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.2 0.0 0.1 0.0 0.0 0.0 10.9 0.0 0.1 0.6 0.0 0.2 2.8 0.3 2.8 2.2 1.4 1.2 1.1 1.2 0.7 0.0 0.0 0.0 2.4 0.0 0.5 0.0 5.8 1.2 0.0 3.1 0.0 0.9 0.0 0.0 1.5 0.9 0.0 0.0 40.4 0.0 3.0 0.2 0.0 0.8 2.3 3.9 1.7 5.0 1.8 1.4 2.2 3.6 1.9 2.4 29.8 391.0 17.5 1.5 2.2 7.5 6.9 5.1 5.3 30.7 26.2 0.0 0.0 1.7 0.8 0.4 4.5 0.0 0.0 2.3 0.1 9.4 0.6 12.8 7.8 4.6 44.5 0.0 9.2 74.8 0.0 17.5 19.9 11.8 10.8 0.0 11.0 1.1 0.0 11.3 15.2 0.9 0.0 3.9 0.2 0.4 2.8 0.3 0.8 0.0 0.5 LRSAM1 "CMT2P, FLJ31641" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451486-127503501 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favorable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favorable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 9.5 13.6 15.6 10.1 17.2 15.3 9.2 24.2 22.6 10.7 18.0 15.3 10.9 10.8 12.6 17.6 12.3 11.0 11.9 18.7 13.3 17.3 11.2 15.6 11.7 11.5 13.5 22.7 16.0 9.6 17.6 11.8 9.2 17.9 13.6 8.6 10.2 11.9 13.7 20.4 28.3 11.1 16.0 18.7 12.6 12.2 6.1 13.9 5.5 11.6 9.6 11.5 17.2 12.9 4.1 5.4 17.4 6.6 1.3 4.8 3.2 5.7 8.8 5.3 10.2 9.0 8.9 8.4 5.4 6.8 8.4 6.2 10.1 5.6 9.9 5.6 7.5 4.3 19.1 6.5 11.4 3.3 10.4 4.9 5.4 11.4 8.8 7.2 5.9 11.4 5.1 9.4 5.7 11.0 10.8 9.0 8.2 4.7 10.3 3.7 14.6 4.1 5.1 5.0 13.4 8.9 6.7 4.8 15.4 9.1 5.0 9.8 8.1 3.5 12.1 7.1 5.3 24.9 3.2 10.5 5.6 5.7 7.0 3.7 11.4 8.5 1.6 9.3 5.5 2.9 14.6 4.9 17.4 4.4 6.6 4.8 4.1 3.0 3.7 5.4 3.1 1.5 2.0 5.7 1.3 5.5 4.6 2.4 3.2 15.6 17.2 24.2 22.6 13.3 17.3 13.5 22.7 17.9 13.9 8.9 4.6 2.7 2.8 1.0 5.6 18.3 5.1 6.7 10.3 0.0 5.9 4.1 5.0 5.4 0.6 3.6 5.6 0.0 1.2 1.7 2.4 3.6 9.2 5.9 5.4 11.1 1.2 4.3 6.6 0.2 2.6 4.5 3.3 10.8 5.2 5.7 4.2 4.3 4.9 5.0 4.8 0.0 4.1 4.6 3.0 2.4 5.8 5.0 4.9 3.0 LRTOMT "CFAP111, COMT2, DFNB63, LRRC51" ENSG00000184154 "Leucine rich transmembrane and O-methyltransferase domain containing" "Q8WZ04, Q96E66" 11 72080331-72110782 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Hearing, Neurotransmitter degradation" "Methyltransferase, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 49.8;testis: 47.8" "Group enriched" "Detected in many" 10 "Early spermatids: 522.5;Late spermatids: 1781.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 27.7" HPA039949 Approved Uncertain Microtubules NA NA Microtubules "HPA039949: AB_10960708" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (1.85e-2)" "prognostic favorable (7.70e-4)" "unprognostic (8.09e-2)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.36e-4)" "unprognostic (6.12e-2)" "unprognostic (8.43e-2)" "unprognostic (2.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" 3.5 3.7 10.6 2.0 11.1 2.1 7.1 3.7 8.9 7.1 4.2 14.0 6.1 3.2 6.0 13.6 3.5 49.8 5.3 2.6 8.8 7.6 9.0 6.2 6.2 2.6 7.7 8.5 8.5 7.0 7.1 8.9 4.4 10.6 7.5 6.2 7.3 4.3 4.7 5.2 4.5 2.5 4.8 7.7 3.2 3.6 47.8 8.9 3.1 9.3 2.4 3.5 3.5 2.6 4.3 4.2 9.2 2.9 10.1 6.2 2.0 2.6 9.8 6.2 5.0 5.4 4.8 1.5 3.1 2.5 2.8 2.5 4.7 14.3 3.4 4.7 5.3 6.9 5.3 4.4 7.4 3.2 6.4 4.3 2.5 4.5 3.3 0.9 2.0 2.7 2.1 3.8 4.3 3.3 4.6 1.0 7.2 2.7 5.3 4.1 9.3 6.0 4.0 3.1 15.4 2.6 7.3 6.3 5.2 11.0 3.2 5.8 4.5 6.1 14.0 7.5 4.5 27.7 2.4 4.6 3.0 4.2 8.0 2.1 5.7 6.2 3.9 2.9 1.7 3.3 2.3 2.9 5.0 3.1 2.8 3.2 4.2 3.3 2.6 1.7 4.3 3.0 3.0 9.2 10.1 1.8 4.2 6.2 2.0 10.6 11.1 3.7 8.9 8.8 7.6 7.7 8.5 10.6 8.9 0.0 1.0 6.1 6.6 2.1 3.7 1.7 5.1 115.1 9.1 3.5 11.8 11.0 10.0 6.1 522.5 4.5 3.1 0.0 2.1 6.7 4.1 11.4 0.0 5.6 2.7 6.4 1.2 3.1 1.0 1781.2 13.8 2.2 1.7 1.8 8.8 12.6 1.8 2.9 9.6 14.6 12.6 6.5 7.1 69.5 22.8 2.0 11.0 2.6 4.3 4.7 MAK "dJ417M14.2, RP62" ENSG00000111837 "Male germ cell associated kinase" P20794 6 10762723-10838555 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 38.1;testis: 19.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 347.5;Early spermatids: 112.5;Rod photoreceptor cells: 298.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 7 "pons and medulla: 10.6" "Cell type enriched" "Detected in single" 13 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 11.7" "Cell line enhanced" "Detected in some" "HDLM-2: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (1.23e-3)" "unprognostic (8.77e-3)" "unprognostic (2.44e-1)" "unprognostic (3.81e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-3)" "unprognostic (1.97e-2)" "unprognostic (2.53e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (6.73e-2)" "unprognostic (6.59e-5)" "unprognostic (1.55e-1)" "unprognostic (8.40e-2)" "unprognostic (7.71e-3)" "unprognostic (4.59e-2)" 0.6 0.3 0.7 0.7 1.5 1.4 0.7 0.4 0.4 0.8 0.2 3.5 0.3 0.2 0.6 2.9 0.3 8.6 1.0 0.3 1.1 1.2 0.3 0.2 1.8 3.7 0.2 0.1 2.2 0.5 9.3 3.6 0.2 10.6 0.5 0.0 38.1 0.5 0.4 0.2 1.1 0.4 0.1 0.7 1.4 0.5 19.3 0.7 0.0 0.6 0.4 0.2 0.2 1.2 0.6 0.4 11.7 0.8 0.3 0.7 0.1 3.0 0.9 1.8 1.8 0.1 0.0 1.7 0.0 0.2 1.0 1.0 1.3 1.7 0.9 0.7 0.0 2.9 0.5 0.6 0.3 0.4 4.7 1.9 0.7 0.7 1.2 0.0 3.2 2.9 0.1 0.0 0.2 0.3 0.6 0.0 0.6 1.6 0.6 0.1 0.4 0.4 1.9 0.8 0.1 0.4 0.6 0.8 0.3 0.1 0.4 1.9 0.9 0.1 0.5 0.1 1.4 1.1 0.3 0.2 0.7 1.1 0.2 1.1 0.5 0.1 0.4 0.5 0.6 1.0 0.5 0.8 0.9 0.4 0.5 0.4 0.2 0.4 0.3 0.4 0.6 0.4 0.7 11.7 0.3 0.8 0.4 0.1 0.1 0.7 1.5 0.4 0.4 1.1 1.2 0.2 0.1 10.6 0.7 0.0 5.4 0.0 2.4 0.3 11.3 0.6 0.0 57.6 7.9 3.5 347.5 0.4 0.0 0.3 112.5 1.1 0.0 0.0 0.2 0.7 0.4 1.2 2.3 0.0 0.2 4.8 0.0 1.3 0.0 27.7 0.6 0.9 1.7 0.0 0.0 15.7 0.1 0.0 0.4 0.0 298.8 0.0 1.0 7.0 6.0 0.4 0.7 0.0 0.0 0.8 MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350541 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 24 "neutrophil: 37.5" "Lineage enriched" "Detected in many" 36 "granulocytes: 37.5" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 27.2;OE19: 28.5;RPTEC TERT1: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 28000000 "Golgi apparatus, Vesicles" "HPA007955: AB_1079306, HPA007956: AB_1079305" "unprognostic (5.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.46e-3)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-2)" "unprognostic (9.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.03e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.15e-2)" "unprognostic (4.46e-2)" "unprognostic (3.65e-1)" "unprognostic (1.03e-2)" 13.1 8.8 9.7 5.1 13.7 4.2 14.7 10.1 18.4 13.5 17.8 7.5 12.9 13.4 15.1 14.1 27.3 11.2 19.3 7.9 9.2 7.6 9.5 7.6 8.4 6.6 6.9 9.0 11.3 26.4 18.5 19.5 11.0 9.0 15.0 18.5 12.8 42.6 15.2 3.6 13.3 13.3 14.4 5.8 8.4 21.3 9.1 6.2 0.0 9.5 16.7 18.2 12.6 12.9 0.2 0.2 37.5 0.5 0.2 1.0 0.1 0.1 3.0 0.9 0.0 3.1 3.0 3.3 2.1 2.5 1.1 1.4 2.5 9.7 0.0 2.3 2.0 1.1 0.4 3.8 1.7 0.8 0.0 3.4 4.3 3.8 2.0 0.5 0.6 1.2 1.9 2.9 0.7 0.5 7.6 27.2 0.1 2.7 0.0 0.3 5.7 0.0 0.3 3.4 28.5 1.6 0.1 0.0 0.0 14.1 9.9 1.3 5.4 1.1 9.1 3.1 1.6 8.2 2.7 10.6 1.5 1.3 0.4 2.8 0.2 0.1 1.4 1.1 0.0 1.1 1.5 0.5 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.2 1.0 0.1 37.5 0.2 0.1 0.0 0.0 0.1 9.7 13.7 10.1 18.4 9.2 7.6 6.9 9.0 9.0 6.2 8.9 20.5 6.9 7.0 3.5 6.8 2.1 28.1 18.7 6.8 22.7 7.9 28.7 1.7 15.0 0.8 20.4 18.1 0.0 33.2 5.4 6.9 10.2 2.3 7.5 6.5 9.5 20.8 30.1 5.9 1.8 12.7 1.4 0.0 1.0 32.2 11.7 15.8 28.1 15.6 1.6 12.6 0.0 4.7 1.7 1.5 4.1 14.2 4.4 25.5 7.2 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386817-66492312 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 62000 "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 28.6 16.9 33.9 19.1 54.1 29.0 23.6 32.5 48.4 12.5 12.1 8.4 10.2 10.0 11.8 16.5 22.0 10.6 14.4 19.1 49.2 26.4 15.3 53.1 16.4 23.3 17.6 31.2 13.5 11.7 23.4 12.0 15.4 17.2 14.4 12.9 9.1 13.2 12.4 39.5 12.3 10.9 16.9 17.4 14.5 10.8 7.8 12.6 12.6 12.3 9.7 27.9 13.6 18.7 4.6 16.2 5.5 8.2 8.4 7.9 2.7 33.6 15.9 31.9 13.3 19.3 14.5 18.5 24.4 20.9 26.5 23.7 23.8 27.7 30.9 30.3 20.1 20.2 30.0 29.8 35.7 31.3 24.9 17.8 9.9 16.6 12.9 15.6 13.0 14.8 11.2 22.1 19.2 28.5 28.3 20.7 15.8 17.5 39.6 38.7 13.0 10.5 17.1 16.3 31.2 13.9 11.9 19.7 27.5 25.7 14.5 19.7 11.0 19.8 15.5 20.5 26.9 14.0 11.2 28.5 34.6 21.2 24.4 36.2 24.5 43.6 19.7 36.5 23.1 16.1 3.2 8.2 5.5 7.4 8.2 6.7 3.0 6.6 6.9 8.3 4.6 7.9 4.9 3.9 8.4 7.3 16.2 4.9 2.7 33.9 54.1 32.5 46.9 49.2 26.4 17.6 31.2 17.2 12.6 26.8 21.9 30.2 40.5 73.6 8.5 16.9 38.2 6.7 13.6 24.4 13.7 40.9 39.7 65.3 10.2 19.0 20.0 46.7 20.4 39.4 31.3 59.4 9.2 116.5 44.9 9.5 20.8 17.2 91.3 18.3 20.8 67.7 50.6 88.4 17.0 33.9 70.1 21.0 20.5 28.5 5.6 6.5 53.6 16.3 44.5 58.8 43.3 40.5 16.8 65.5 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124129 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Late spermatids: 596.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 23.9 33.0 35.6 27.6 36.1 46.7 30.2 31.2 43.4 22.6 38.8 24.6 27.0 70.9 21.8 23.2 32.8 21.7 27.9 41.4 33.1 31.0 22.7 42.0 24.1 44.5 34.4 29.2 30.8 46.0 18.9 29.7 21.3 26.1 25.7 24.3 21.7 41.5 24.0 134.9 27.4 56.7 19.0 25.2 25.9 28.3 42.0 20.9 44.1 26.2 42.2 29.1 20.0 26.9 11.4 10.7 28.3 10.6 11.3 12.1 4.5 36.8 40.7 22.3 31.3 30.9 37.3 22.3 24.3 32.6 33.3 30.2 35.2 20.0 31.6 23.0 27.7 26.8 26.6 17.4 26.0 25.8 26.8 21.2 11.5 22.2 38.9 47.3 21.1 24.3 41.1 25.3 23.4 31.2 44.6 29.4 28.8 22.0 62.4 28.0 46.3 41.8 29.7 25.5 27.2 29.6 32.0 14.7 36.1 29.1 23.7 30.3 30.2 22.3 30.9 75.8 26.9 23.8 36.4 25.9 27.3 23.8 69.8 37.4 62.8 38.0 22.1 42.4 38.2 46.8 15.2 9.1 28.3 11.9 10.6 9.7 8.9 9.7 12.1 10.7 11.4 8.9 11.6 14.4 11.3 8.7 6.0 9.2 4.5 35.6 36.1 31.2 43.4 33.1 31.0 34.4 29.2 26.1 20.9 8.9 38.8 57.0 73.8 31.5 79.0 54.9 17.8 10.7 19.4 38.4 39.3 23.7 124.3 17.7 223.1 33.7 242.0 0.0 38.5 28.5 33.0 88.2 19.6 43.1 46.2 114.4 60.6 34.4 35.6 596.7 33.1 29.7 40.5 12.6 77.6 82.3 41.7 90.9 21.5 75.0 82.4 25.8 32.5 25.9 14.5 55.8 29.7 45.4 69.4 97.8 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.4 21.7 2.9 13.2 17.6 11.3 11.0 33.2 36.1 26.5 24.4 24.1 13.8 19.4 13.6 52.0 22.4 21.3 9.2 29.5 18.9 20.1 16.8 11.2 12.5 21.8 5.5 14.7 23.1 8.7 8.4 36.1 10.9 8.3 11.8 11.4 2.1 9.7 22.1 21.3 7.4 14.0 8.3 38.6 12.5 15.3 18.7 14.3 15.0 22.6 7.9 2.8 12.3 13.3 23.1 30.1 6.6 5.0 10.8 25.2 20.6 26.9 21.4 12.1 6.1 25.0 24.3 12.7 13.0 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 35.7 59.6 38.8 149.8 229.1 5.9 17.0 45.9 29.4 45.5 21.0 3.9 51.1 63.0 81.6 1.1 21.1 72.0 210.2 69.2 75.4 38.0 143.0 94.4 63.8 45.6 17.5 115.4 21.5 64.9 0.7 11.2 56.1 82.7 15.4 50.2 16.4 93.5 56.1 15.6 27.9 6.9 0.0 70.0 0.9 4.4 190.7 56.1 56.1 31.9 222.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SuSa: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: AB_2684197" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 10.6 9.2 12.1 6.2 6.7 8.7 7.7 7.3 9.6 8.3 8.0 5.4 3.7 4.4 5.9 11.3 5.4 7.1 10.5 10.1 12.5 7.8 12.3 4.9 5.4 10.2 7.9 4.7 7.4 7.2 10.0 9.7 10.2 8.6 7.5 6.3 5.2 2.6 10.4 3.9 5.6 4.4 7.0 11.5 4.5 7.0 13.6 3.0 11.4 6.9 2.4 7.2 8.4 4.5 7.0 67.1 5.7 3.4 6.8 4.1 6.3 5.6 8.6 5.1 5.7 3.5 7.7 3.7 5.9 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 8.9 14.2 10.8 26.3 36.9 14.2 21.2 10.2 2.7 21.6 14.0 7.9 10.7 21.6 11.2 6.3 8.7 11.8 0.0 12.4 8.6 12.9 32.3 1.1 16.3 10.2 17.5 11.5 10.4 17.7 5.8 10.9 11.7 11.8 19.0 13.8 10.3 14.7 11.5 12.0 17.7 9.7 12.9 12.0 7.9 8.1 34.4 21.2 9.5 10.6 40.3 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542709-67807123 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 115.1;Late spermatids: 149.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules NA NA "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favorable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 18.6 22.2 20.3 13.8 30.9 14.6 23.7 25.0 25.4 17.0 19.3 17.2 19.9 14.7 17.4 11.3 13.5 16.2 14.4 18.8 17.1 16.4 14.2 15.5 13.5 27.9 12.6 11.5 29.0 21.0 34.1 14.4 17.7 22.2 15.9 14.8 15.6 15.7 18.5 28.5 18.7 15.0 19.4 17.2 13.0 15.4 20.3 16.2 40.2 16.9 9.2 11.9 17.0 17.9 6.6 10.2 10.3 7.3 11.7 11.2 5.5 5.3 14.2 8.5 10.0 12.6 22.2 6.7 5.4 10.9 10.1 11.1 5.7 9.6 8.8 11.4 8.9 11.0 8.1 14.5 8.6 8.4 12.8 14.5 12.0 10.6 6.1 15.9 7.2 7.5 15.2 11.3 7.3 16.6 22.3 13.3 20.5 10.5 14.8 8.3 6.9 11.8 8.6 12.0 6.2 6.9 11.7 9.9 14.7 6.1 9.8 5.4 8.4 6.0 8.9 21.4 15.4 11.2 14.2 11.0 10.5 6.9 7.2 7.2 21.0 24.6 10.3 14.0 16.6 7.5 10.3 7.3 6.6 7.7 5.6 11.2 6.6 7.3 9.0 10.2 6.2 10.4 9.5 1.7 11.7 6.2 3.9 7.4 5.5 20.3 30.9 25.0 25.4 17.1 16.4 12.6 11.5 22.2 16.2 6.0 4.3 4.2 7.5 6.2 10.0 8.0 2.5 1.4 1.2 5.2 9.8 10.3 6.6 7.7 115.1 7.0 8.8 0.0 7.4 9.1 7.1 4.5 2.3 6.8 8.8 4.8 9.1 9.8 9.2 149.4 11.5 5.3 10.1 2.8 8.4 16.0 6.9 10.5 11.0 6.8 7.2 0.0 5.1 10.4 8.2 7.2 8.2 8.7 9.4 2.7 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414698-69553861 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.9;skeletal muscle: 55.6" "Cell type enhanced" "Detected in many" 7 "Intestinal endocrine cells: 43.8;Muller glia cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 9.3;neutrophil: 19.3;plasmacytoid DC: 31.9" "Group enriched" "Detected in all" 9 "dendritic cells: 31.9;granulocytes: 19.3;monocytes: 9.3" "Cell line enhanced" "Detected in many" "A549: 24.4;AN3-CA: 13.3;HUVEC TERT2: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favorable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favorable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 4.5 2.0 3.2 8.6 5.9 10.1 14.0 13.7 7.5 19.8 21.5 6.2 4.7 7.2 4.7 3.1 3.4 3.3 5.1 2.5 3.9 3.5 4.1 8.6 2.6 10.3 5.4 4.1 2.7 8.5 0.0 3.2 1.1 5.3 2.8 22.8 5.3 4.0 4.6 55.6 2.3 7.3 2.3 6.2 5.9 5.4 2.1 5.4 13.7 2.8 4.8 5.1 3.0 2.5 2.3 31.9 19.3 9.3 1.8 2.1 2.6 0.1 24.4 11.0 13.3 4.7 2.6 1.6 0.1 3.6 1.0 1.5 0.7 1.1 0.6 9.0 0.5 0.8 1.2 3.8 0.5 0.3 0.8 2.0 0.1 6.9 6.8 4.7 1.0 1.0 12.1 0.3 0.3 0.0 1.0 17.5 3.3 0.0 1.7 0.0 0.1 12.7 0.5 7.8 0.5 4.5 4.6 1.1 0.3 4.9 3.4 4.9 7.4 1.0 0.9 2.2 6.1 3.4 1.3 3.1 1.3 1.6 1.1 0.4 1.2 1.3 0.3 1.0 1.5 1.0 0.8 9.3 1.6 1.2 1.1 2.1 1.6 1.4 1.5 2.9 2.3 1.6 1.5 19.3 1.8 0.4 31.9 1.9 2.6 3.2 5.9 13.7 7.5 3.9 3.5 5.4 4.1 5.3 5.4 3.0 7.9 4.7 3.2 2.4 4.9 1.4 2.5 6.7 5.7 0.0 2.0 7.5 19.9 1.2 8.5 2.4 17.0 0.0 3.6 5.4 2.8 1.9 1.1 2.0 5.1 3.2 43.8 4.9 8.9 1.9 4.0 7.0 3.3 0.0 22.4 32.9 1.2 8.6 3.5 1.1 3.8 0.0 3.1 0.0 0.2 3.8 0.7 11.5 23.7 2.3 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: AB_2685331" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favorable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favorable (1.56e-4)" 16.3 14.9 13.5 16.4 16.4 23.8 13.6 28.7 21.5 14.3 15.6 23.2 15.1 19.3 19.1 9.9 13.6 13.1 14.3 15.8 14.6 11.9 12.8 15.9 12.5 15.9 17.2 13.9 18.4 22.3 13.9 17.0 16.4 16.2 14.4 7.9 14.2 23.0 13.4 61.6 21.3 18.7 14.1 12.5 19.4 14.8 21.5 16.5 9.8 13.7 17.3 12.8 15.4 15.2 3.0 2.6 4.8 2.7 3.3 2.5 1.0 12.9 7.4 6.4 10.6 5.2 5.0 12.1 8.5 4.2 5.8 6.0 10.7 7.9 15.4 13.8 4.5 5.7 11.9 5.6 6.5 2.3 12.2 27.8 10.8 9.8 7.9 6.7 10.1 13.8 5.8 8.5 4.6 5.2 7.7 5.2 11.3 15.8 20.3 3.3 6.8 14.3 24.5 11.4 6.9 16.7 14.3 7.0 15.6 5.2 10.8 11.9 11.9 5.8 10.2 11.8 4.0 11.0 11.5 7.8 17.7 10.1 12.4 11.5 29.4 13.6 14.5 8.9 14.9 7.1 0.0 2.7 1.9 2.3 2.5 1.5 2.1 1.9 2.0 1.3 3.0 1.7 2.5 4.8 3.3 1.5 2.6 0.7 1.0 13.5 16.4 28.7 21.5 14.6 11.9 17.2 13.9 16.2 16.5 23.8 21.5 21.9 31.0 34.3 50.6 12.6 22.9 9.4 5.7 19.2 72.6 23.2 11.6 19.1 3.8 18.7 26.2 0.0 16.4 25.3 18.1 32.9 10.4 17.4 16.3 54.0 35.1 19.0 12.4 8.6 26.7 15.7 30.4 16.2 23.6 25.8 19.2 21.0 11.7 14.7 70.3 32.3 26.9 14.2 26.4 37.3 41.2 28.0 24.2 25.2 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.5;THP-1: 25.7" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.6 4.0 6.3 4.2 1.0 0.8 10.6 1.3 1.7 4.0 5.6 18.7 5.0 5.9 0.4 1.5 3.4 3.4 5.2 2.3 5.6 2.0 2.3 3.3 1.8 8.8 2.5 5.2 9.2 1.0 2.5 1.2 2.0 1.1 1.7 2.0 2.8 10.7 1.0 2.9 3.6 7.1 2.9 3.4 0.5 5.7 4.4 20.3 7.0 6.9 2.6 27.5 3.9 4.9 11.2 5.8 13.4 25.7 5.0 0.4 3.4 1.5 2.4 7.8 4.0 11.3 0.6 3.1 6.8 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 6.0 9.8 47.7 14.5 46.5 15.2 2.7 50.9 4.0 12.5 34.9 45.2 12.9 6.6 14.2 1.6 13.5 6.6 0.0 12.8 7.7 11.3 11.9 7.0 12.1 26.3 27.0 9.8 17.2 81.7 1.9 4.9 40.3 35.4 45.9 10.1 10.6 13.0 7.0 1.8 20.1 34.7 6.5 5.2 10.0 15.0 47.8 5.6 16.6 8.9 10.0 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191744-40215575 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 13.9;Horizontal cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favorable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favorable (2.13e-4)" 7.7 7.0 29.6 4.7 22.8 3.7 2.2 14.3 32.0 3.3 3.4 5.3 1.8 4.4 4.5 1.8 3.7 3.1 4.0 8.2 28.2 11.2 4.7 2.1 4.2 4.6 11.5 9.4 4.3 8.1 4.7 5.2 3.7 9.0 4.6 2.0 2.4 6.9 4.8 22.9 5.6 5.0 4.0 5.3 6.7 6.2 6.6 7.1 2.3 3.3 2.6 2.4 3.8 5.4 0.8 0.0 0.0 0.2 0.0 0.9 0.0 6.3 7.6 2.4 5.6 2.2 1.3 6.5 4.4 2.2 2.0 2.1 1.7 1.8 5.8 4.6 1.5 5.1 2.1 0.9 2.3 0.3 11.0 7.2 1.5 3.2 1.7 4.2 1.3 3.7 1.2 5.5 2.2 1.5 2.3 1.9 8.2 5.5 9.9 0.6 3.8 4.8 2.3 2.8 2.1 5.0 5.9 2.5 3.4 1.8 4.0 7.9 11.4 5.1 1.9 10.4 1.5 2.5 2.3 3.1 5.4 5.2 7.8 8.5 13.1 7.5 2.6 6.2 2.4 7.8 0.0 0.1 0.0 0.4 0.2 0.0 0.8 0.2 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 29.6 22.8 14.3 28.7 28.2 11.2 11.5 9.4 9.0 7.1 0.0 0.0 2.2 1.5 1.3 13.9 2.4 0.0 0.0 0.0 7.0 7.9 0.6 0.0 2.3 2.6 2.3 2.6 0.0 3.6 0.7 1.9 2.0 0.0 2.6 2.2 22.3 4.1 3.7 2.2 6.5 2.8 1.1 1.7 1.0 1.9 5.2 3.4 1.9 4.6 3.7 7.3 6.5 2.6 2.6 1.7 2.4 1.1 1.9 2.1 1.7 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597755-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 75.8" "Cell type enhanced" "Detected in all" 4 "Enterocytes: 120.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" NA NA "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 23.2 10.8 11.4 23.7 21.2 14.2 27.4 7.9 13.8 8.6 15.8 29.8 6.1 31.9 11.0 8.1 14.7 11.6 12.0 11.6 13.3 8.1 16.1 31.2 21.1 14.4 30.9 8.2 8.4 12.5 8.3 10.3 14.7 16.7 13.4 8.2 15.4 13.5 9.5 11.9 13.7 31.9 8.6 17.7 28.8 16.9 8.6 19.0 8.9 13.6 7.6 12.7 8.9 75.8 2.3 7.6 13.8 12.0 1.8 3.5 5.6 16.7 14.8 8.0 8.5 2.6 3.2 8.2 6.5 4.6 7.8 5.3 14.8 16.3 6.3 24.1 5.1 11.4 14.7 4.8 7.0 2.9 13.9 6.1 17.8 10.1 17.7 7.1 10.2 26.9 5.1 6.8 5.8 5.3 8.3 21.8 7.3 7.7 12.7 4.1 20.8 11.9 19.2 8.8 11.2 19.0 19.8 5.2 12.8 7.4 14.6 7.3 8.2 7.7 22.2 38.1 4.2 17.7 16.6 24.4 12.0 13.0 17.5 11.5 8.1 9.2 5.6 14.0 11.8 27.8 4.3 7.7 9.2 2.4 12.0 2.4 2.0 2.6 3.5 7.6 2.3 2.0 1.5 13.8 1.8 11.7 2.3 1.4 5.6 11.4 21.2 7.9 13.8 13.3 8.1 30.9 8.2 16.7 19.0 20.8 19.7 19.7 21.8 18.7 22.9 9.6 17.8 5.3 6.8 10.4 23.6 21.6 16.6 18.8 9.8 69.5 120.7 23.3 23.8 13.7 11.6 23.2 25.4 45.6 44.4 17.5 40.3 49.7 42.7 44.8 8.9 39.8 20.3 37.9 41.8 14.5 24.8 77.2 6.0 21.1 53.6 32.3 11.2 11.4 13.6 26.2 28.7 21.2 36.5 30.8 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 35.3;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 3.4;monocytes: 1.7;T-cells: 2.8" "Cell line enhanced" "Detected in many" "ASC diff: 26.4;HHSteC: 25.2;HSkMC: 25.1;hTERT-RPE1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA039936: AB_10795239, HPA071996: AB_2686481" "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favorable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavorable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 8.0 8.7 12.3 5.8 16.0 3.0 5.1 40.3 20.6 14.1 6.1 7.0 7.8 3.6 15.1 5.8 4.6 11.5 16.1 4.2 9.4 7.7 4.5 1.4 8.8 4.5 6.4 14.7 13.7 1.8 3.0 12.7 7.3 10.8 5.9 4.6 9.5 2.4 13.5 1.2 4.5 4.1 16.9 5.3 5.3 3.9 6.5 7.4 2.7 4.3 1.4 3.2 11.3 6.4 0.3 0.6 3.4 1.7 0.6 2.8 0.5 0.2 7.0 4.4 6.8 26.4 14.1 0.5 4.7 8.9 5.2 5.3 0.1 0.8 1.5 2.7 5.1 4.2 0.0 2.0 3.1 2.1 2.3 2.4 1.7 3.6 0.0 25.2 0.0 1.7 25.1 2.3 7.1 3.7 33.3 8.1 3.5 0.0 7.5 4.9 3.0 1.7 0.3 1.5 0.0 2.6 2.4 2.9 0.4 2.6 0.0 4.4 6.0 2.5 3.2 6.7 1.0 2.2 4.4 5.9 5.0 5.4 2.3 1.2 3.0 3.4 0.0 8.1 3.0 4.9 0.0 1.7 0.0 1.5 1.3 2.8 0.3 2.1 2.3 0.6 0.0 0.9 1.2 3.4 0.6 0.4 0.3 0.4 0.5 12.3 16.0 40.3 20.6 9.4 7.7 6.4 14.7 10.8 7.4 6.0 13.4 5.6 1.9 0.7 26.7 0.7 10.2 8.1 11.4 1.8 35.3 1.6 8.3 5.4 1.2 3.7 4.6 0.0 1.6 1.8 3.8 2.7 12.7 7.7 3.6 28.6 3.4 7.4 12.7 1.4 7.5 5.9 0.0 7.2 2.5 17.4 4.5 2.6 7.8 7.0 81.9 6.5 4.9 2.3 1.9 0.9 1.8 7.5 3.5 2.0 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489097 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "monocytes: 456.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favorable (1.11e-4)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 9.8 24.8 21.7 8.7 22.2 9.5 15.1 16.4 26.1 12.9 16.9 18.4 10.5 16.8 12.9 42.1 15.2 14.6 13.1 8.1 19.2 18.6 21.9 20.7 15.2 7.4 23.2 17.1 16.5 24.9 20.9 24.5 9.1 21.8 14.5 18.9 18.6 26.2 11.4 3.3 9.8 23.4 12.1 26.4 8.7 16.4 12.9 15.8 4.4 18.6 8.3 10.3 12.5 11.5 23.7 21.5 21.1 13.2 11.5 17.4 7.8 29.1 5.8 11.3 0.3 10.3 12.7 6.7 6.7 4.6 10.9 13.2 11.2 11.0 0.2 23.0 12.2 18.2 16.7 0.3 15.5 19.4 32.5 15.0 0.1 7.9 9.2 11.2 15.3 8.4 11.5 13.6 9.3 11.7 11.3 12.1 0.3 0.3 23.7 9.7 9.1 1.8 7.2 13.0 22.5 13.7 0.2 13.5 16.0 19.2 7.6 18.6 12.4 11.3 17.1 23.2 12.9 25.8 8.6 8.0 9.0 11.7 16.2 14.5 12.1 15.6 9.6 13.2 7.8 14.7 6.4 13.2 5.1 10.3 12.2 15.8 23.7 12.4 12.8 21.5 19.0 17.4 16.8 21.1 11.5 8.6 9.4 4.8 7.8 21.7 22.2 16.4 26.1 19.2 18.6 23.2 17.1 21.8 15.8 50.6 76.2 44.7 172.9 125.7 111.5 22.1 104.4 64.3 84.2 75.0 86.4 120.9 243.7 92.5 109.7 52.6 82.0 0.0 111.2 29.4 48.3 249.1 28.9 83.1 55.4 42.9 102.2 83.4 50.4 168.4 40.0 59.4 81.0 456.3 109.9 93.7 112.0 96.2 50.9 224.8 81.3 45.3 74.0 119.3 28.8 127.2 170.1 31.2 98.7 249.0 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263121-45317040 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "monocytes: 49.5" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 22.4;HDLM-2: 23.0;U-251 MG: 22.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_2732436, HPA027270: AB_2732437" "unprognostic (1.05e-2)" "prognostic favorable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 3.7 3.4 3.0 14.7 4.0 3.4 2.7 4.9 3.6 5.0 7.3 4.5 3.5 6.0 5.5 3.3 6.8 4.2 6.2 4.5 3.0 4.4 5.1 4.9 12.0 3.0 0.6 3.5 5.7 3.5 7.7 1.5 4.6 5.2 3.5 4.3 7.5 4.8 14.5 6.1 9.6 5.2 4.1 8.4 4.0 4.5 4.5 7.1 2.2 6.9 18.0 4.9 2.8 9.5 4.8 7.7 3.6 5.6 5.2 2.3 9.5 22.4 2.3 4.0 1.6 3.8 5.7 2.6 1.8 8.5 5.2 3.4 11.9 4.2 13.6 2.8 8.5 6.8 1.0 3.6 4.4 23.0 1.7 0.9 6.1 1.5 4.1 0.7 4.5 5.9 2.3 4.2 2.2 9.0 1.6 2.0 1.8 18.3 4.3 3.5 4.0 1.5 1.2 5.9 3.1 5.2 6.9 9.6 6.2 1.9 2.4 1.9 4.1 2.7 2.9 3.4 1.7 0.4 3.6 3.9 6.0 3.3 22.5 17.5 6.5 2.2 2.2 2.5 5.2 1.5 3.4 1.6 3.5 3.6 2.0 7.6 2.4 2.5 2.3 9.5 2.6 2.5 7.7 5.6 2.2 4.8 5.2 2.3 3.0 13.8 9.7 13.7 0.0 3.6 2.0 15.3 9.4 4.5 0.0 3.9 0.7 0.0 4.2 3.7 1.6 11.2 0.0 2.3 1.2 1.8 6.5 1.1 8.1 4.4 1.6 12.6 4.9 7.8 4.5 4.4 6.2 0.0 49.5 6.4 2.2 3.3 7.8 1.1 2.5 2.7 0.0 0.6 4.5 2.4 0.0 0.0 5.1 6.7 5.0 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.3;brain: 13.2" "Cell type enhanced" "Detected in some" 12 "Alveolar cells type 2: 1.9;Cardiomyocytes: 2.5;Collecting duct cells: 5.2;Cone photoreceptor cells: 3.9;Distal tubular cells: 3.3" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 6 "pons and medulla: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.2;HAP1: 7.9;HEK 293: 6.7;JURKAT: 3.9;REH: 4.1;SuSa: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.1 17.3 0.5 0.4 0.3 0.5 0.1 2.3 0.1 0.1 0.1 5.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.5 3.6 0.1 0.5 0.0 0.1 0.0 1.3 4.1 0.4 5.7 0.0 13.2 0.1 0.0 4.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 2.6 0.1 2.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.4 0.0 7.9 0.0 0.0 1.3 6.7 2.7 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.5 0.0 0.0 0.2 0.0 2.1 2.0 0.0 0.8 4.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.3 0.1 0.4 0.5 0.1 0.0 13.2 0.0 0.0 1.9 0.0 0.6 0.1 0.6 2.5 0.0 0.0 0.0 5.2 3.9 0.0 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.2 1.2 0.0 0.1 0.0 0.0 0.0 MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298730-127388465 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA021540: AB_2670742" "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (7.19e-2)" "unprognostic (4.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" 18.5 14.5 13.7 20.1 14.5 41.0 22.6 20.1 16.3 16.6 19.6 12.7 18.9 18.8 19.8 18.0 13.4 15.9 18.6 13.3 12.5 10.2 15.5 27.6 20.0 28.5 17.9 13.0 20.3 15.4 23.8 21.2 13.9 12.3 13.6 13.1 12.2 18.1 25.5 24.5 19.4 22.5 18.1 14.9 17.0 18.0 14.9 14.3 25.8 22.5 13.7 16.8 17.1 20.3 3.1 5.1 13.6 2.9 2.3 2.1 1.1 16.4 7.0 5.6 5.7 7.9 10.5 9.4 10.3 11.2 10.2 8.3 8.4 7.3 10.9 17.8 14.7 9.4 14.0 9.0 6.9 11.5 27.3 7.0 10.1 12.8 7.3 9.2 10.1 21.9 9.4 7.6 12.3 15.2 9.0 4.7 8.2 4.7 21.8 10.0 6.0 11.9 7.2 5.8 4.6 9.2 7.8 10.6 8.1 4.1 15.5 11.2 6.0 15.0 9.2 9.3 4.8 6.0 7.8 10.7 20.0 18.8 9.2 13.9 22.7 16.3 11.2 9.6 6.7 8.6 4.0 2.9 2.0 1.7 1.8 2.1 3.1 1.6 1.7 2.4 2.6 1.9 2.0 13.6 2.3 2.2 5.1 1.4 1.1 13.7 14.5 20.1 16.3 12.5 10.2 17.9 13.0 12.3 14.3 77.4 39.5 24.5 32.1 64.0 51.3 27.5 38.2 57.6 46.6 27.9 100.1 16.2 11.6 17.3 3.2 38.8 49.0 23.3 29.5 16.3 51.8 41.5 60.0 61.1 46.1 68.3 43.6 22.1 61.3 3.8 39.1 76.0 54.0 23.4 36.2 25.5 35.7 24.6 48.8 27.2 56.9 19.4 48.6 31.4 55.2 68.6 22.0 30.5 24.4 35.7 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268010 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 96.1" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 1: 35.7;Alveolar cells type 2: 51.9;Cytotrophoblasts: 48.5;Ductal cells: 34.2;Pancreatic endocrine cells: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 13.7" "Group enriched" "Detected in many" 5 "dendritic cells: 13.7;monocytes: 8.0" "Cell line enhanced" "Detected in many" "hTERT-HME1: 44.9;U-138 MG: 48.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA NA Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 21.7 5.0 2.9 7.4 3.3 0.8 9.2 2.8 3.1 25.7 24.8 2.1 10.7 3.1 30.2 15.4 26.2 13.1 14.9 52.5 3.5 3.0 2.4 8.5 7.5 2.5 4.5 3.0 21.7 4.4 22.6 3.1 6.9 4.2 25.6 5.4 11.5 6.7 15.8 96.1 5.8 8.0 68.4 4.7 3.7 15.8 6.6 3.5 2.8 6.7 38.0 4.9 46.7 24.0 2.1 13.7 2.3 8.0 0.4 1.6 2.7 8.9 7.5 5.9 7.8 17.3 25.8 3.7 32.3 25.3 15.1 16.3 5.1 5.9 6.9 8.5 32.3 13.3 6.1 8.8 17.1 34.1 13.4 5.9 11.2 8.5 1.0 6.9 10.0 11.9 20.7 7.4 28.4 44.9 12.6 10.0 7.6 5.0 1.3 9.9 3.8 6.3 5.0 3.3 7.5 4.3 9.3 12.1 0.0 3.7 5.1 3.5 3.4 12.4 3.0 5.3 10.1 3.4 5.4 10.0 48.3 19.8 14.3 7.3 0.0 0.0 1.4 34.7 2.7 5.0 0.1 8.0 0.0 0.9 7.5 0.9 1.5 0.8 1.6 13.7 2.1 0.0 0.8 2.3 0.4 6.6 0.3 0.7 2.7 2.9 3.3 2.8 3.1 3.5 3.0 4.5 3.0 4.2 3.5 35.7 51.9 0.0 0.0 0.0 0.0 0.0 0.0 24.1 13.6 10.4 0.0 48.5 1.7 34.2 0.0 0.0 0.0 0.0 23.2 22.4 0.0 0.0 4.7 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 27.1 0.0 0.0 31.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327768-233385148 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.9" "Cell type enhanced" "Detected in some" 18 "Alveolar cells type 1: 32.8;Alveolar cells type 2: 7.7;Collecting duct cells: 14.0;Ductal cells: 9.7;Exocrine glandular cells: 8.4;Pancreatic endocrine cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.0" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.0" "Cell line enhanced" "Detected in many" "HEK 293: 18.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.6 3.2 2.0 3.4 2.2 1.3 2.2 10.0 3.3 1.5 11.4 0.6 9.1 9.9 0.8 5.2 2.4 3.9 3.9 0.7 1.3 2.1 12.5 13.3 5.6 0.5 0.9 1.7 0.8 28.9 4.4 2.6 1.0 1.2 1.3 6.0 1.0 3.7 2.5 0.4 2.7 17.2 0.3 0.9 0.7 10.1 12.4 0.6 0.5 2.4 0.8 1.3 1.1 1.6 0.5 0.8 0.1 0.3 5.0 0.2 0.1 7.4 12.7 0.2 0.0 0.0 0.0 6.4 0.2 0.0 0.3 0.5 7.0 6.5 0.7 5.2 0.1 2.4 4.0 9.5 3.9 0.8 13.8 18.3 0.1 7.1 0.0 0.5 12.1 2.9 0.1 5.2 0.2 7.4 1.4 0.4 5.8 0.1 2.4 0.0 1.6 3.8 4.3 9.1 8.7 5.6 0.0 0.0 13.3 8.8 3.1 9.4 2.5 4.3 0.2 0.0 1.0 3.7 3.9 0.0 0.0 1.2 0.0 7.4 2.3 2.9 0.0 1.2 3.3 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.8 0.5 0.0 0.0 0.1 5.0 0.0 0.2 0.2 0.1 2.0 2.2 10.0 3.3 1.3 2.1 0.9 1.7 1.2 0.6 32.8 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 14.0 0.0 0.0 3.3 9.7 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 7.8 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696303 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "CAB007764: AB_562314, HPA035410: AB_2674614, HPA035411: AB_2674615" "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 23.9 11.8 10.5 20.5 15.0 24.8 19.1 26.8 14.9 22.2 21.8 15.0 14.0 8.0 24.5 13.2 16.6 18.3 20.6 37.4 11.3 8.4 17.1 12.4 23.1 21.4 14.4 9.6 21.6 11.4 16.9 12.3 21.0 11.9 18.4 8.3 21.7 12.8 18.5 19.6 15.4 14.7 20.4 13.2 30.4 16.4 26.5 12.3 12.9 15.5 12.8 15.4 19.0 26.8 1.9 3.5 18.3 8.5 1.1 2.6 2.3 10.2 7.7 9.8 9.6 18.9 15.2 4.5 10.2 11.2 12.7 10.3 3.5 2.1 11.1 7.2 19.9 9.3 3.8 6.4 7.2 8.1 9.7 14.1 9.0 10.5 5.0 9.9 6.9 9.7 10.9 5.0 15.8 8.3 8.1 30.8 8.2 5.5 14.7 10.1 7.3 12.4 7.3 6.1 2.1 8.3 6.6 25.2 7.2 4.6 4.7 5.0 12.1 6.9 8.3 8.5 12.9 8.3 6.9 27.7 32.5 8.6 17.6 12.3 14.7 14.8 4.1 7.0 5.6 8.4 8.8 8.5 10.4 2.2 8.3 2.3 1.5 2.6 2.1 3.5 1.9 2.5 2.5 18.3 1.1 8.2 1.3 1.9 2.3 10.5 15.0 26.8 14.9 11.3 8.4 14.4 9.6 11.9 12.3 17.9 12.6 8.8 5.9 6.9 13.9 9.9 2.5 4.0 5.7 15.7 13.7 2.7 8.3 3.7 7.1 33.7 2.1 0.0 6.9 2.9 7.4 8.9 3.5 8.3 13.8 17.5 4.1 39.3 38.3 4.4 13.8 15.3 21.9 8.2 3.3 7.5 4.9 0.0 12.4 2.1 15.0 19.4 11.4 18.0 6.1 9.8 1.1 8.7 4.4 3.7 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol NA NA Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 12.0 8.0 13.1 17.7 12.6 9.1 14.6 23.1 14.0 16.4 13.9 9.3 12.2 9.5 22.2 11.9 21.4 14.1 11.4 12.4 11.9 7.8 9.4 8.2 15.9 14.4 12.8 8.9 17.4 12.1 15.8 16.2 12.4 9.2 14.2 9.8 9.4 15.0 15.4 24.4 15.1 13.3 13.9 7.7 10.6 11.1 13.5 12.4 16.2 10.6 13.0 16.8 15.8 23.9 8.8 5.4 17.5 3.8 3.5 8.9 2.2 4.7 5.4 10.3 8.8 6.4 7.5 6.7 5.4 4.8 6.2 6.6 7.7 3.5 9.8 3.9 13.7 8.9 11.9 10.5 10.8 7.6 7.1 8.6 12.8 5.0 7.5 4.9 13.2 6.2 4.7 12.6 6.5 5.9 9.7 8.1 7.4 32.2 11.3 6.6 4.9 8.9 6.7 6.3 3.4 8.3 9.8 9.5 7.8 5.7 3.5 5.9 5.3 10.1 10.8 0.9 9.4 4.4 16.2 7.5 7.6 9.8 7.1 25.5 6.6 5.3 9.0 9.0 13.7 8.0 17.5 3.8 2.3 5.0 3.0 8.9 6.2 7.1 4.5 4.3 8.8 5.0 4.9 0.2 3.5 1.7 5.4 4.8 2.2 13.1 12.6 23.1 14.0 11.9 7.8 12.8 8.9 9.2 12.4 17.9 12.6 14.2 8.2 8.8 15.7 17.9 10.2 8.1 19.4 14.0 21.6 16.7 3.3 8.0 2.6 11.3 5.9 0.0 6.5 9.4 7.8 10.8 3.5 7.3 6.4 22.3 14.8 4.3 7.0 2.5 10.6 9.0 0.0 18.0 9.4 18.9 9.7 7.0 11.7 5.9 28.6 6.5 8.0 13.5 29.6 10.3 27.7 12.1 10.9 12.9 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557047-136792518 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 55.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol NA NA Cytosol "CAB007824: AB_598175, HPA063245: AB_2684969" "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favorable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 7.7 55.6 13.0 7.5 17.6 7.6 5.5 12.9 12.7 4.0 5.4 6.9 3.6 4.6 7.2 5.1 6.4 6.1 4.9 7.3 11.8 6.8 6.8 5.5 7.7 8.8 8.2 6.4 32.4 28.2 1.5 9.9 3.4 7.9 11.6 6.2 5.8 4.2 4.9 3.7 5.0 4.6 4.3 7.5 9.8 8.7 7.3 8.6 2.0 10.0 3.4 9.0 10.8 18.9 2.5 2.5 8.5 3.0 4.1 7.0 1.4 2.9 1.8 0.0 0.0 4.2 11.3 1.0 4.2 22.7 2.2 2.1 0.1 3.0 1.7 6.2 5.8 1.6 4.0 7.2 2.1 5.7 2.3 5.7 15.0 4.0 0.0 20.1 6.9 0.0 14.8 2.8 3.4 9.8 8.4 7.3 2.1 3.7 16.8 15.3 5.6 0.1 5.9 0.7 5.7 2.4 3.9 4.8 6.8 8.8 18.6 5.3 3.5 3.5 3.4 0.9 0.8 0.7 6.2 6.3 3.6 1.1 0.2 3.9 13.7 9.1 0.0 2.8 9.8 3.2 5.7 3.0 3.3 2.7 2.3 4.9 2.0 4.3 3.7 2.5 2.5 0.4 1.4 8.5 4.1 2.1 2.4 7.0 1.4 13.0 17.6 12.9 9.4 11.8 6.8 8.2 6.4 7.9 8.6 6.0 22.4 10.4 17.9 4.4 17.5 21.8 2.5 16.0 34.2 10.4 5.9 0.7 3.3 2.1 4.9 3.8 7.7 0.0 19.7 0.9 5.1 22.3 5.7 9.6 7.1 0.0 33.5 9.8 22.1 2.3 21.9 18.4 0.0 1.0 12.1 42.4 18.9 5.8 13.4 6.8 2.5 12.9 8.0 1.4 15.0 8.8 2.3 6.9 10.0 19.3 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27355184-27366892 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.9" "Cell type enhanced" "Detected in many" 4 "Ito cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 37.5 6.3 7.4 6.9 8.6 1.3 22.1 12.6 8.3 19.9 9.0 2.7 8.9 3.3 13.1 10.3 25.7 12.8 12.4 14.9 6.2 2.6 13.6 5.0 21.7 5.5 11.4 1.9 11.7 8.3 8.2 15.8 7.3 9.8 13.9 5.9 15.7 11.5 9.7 6.3 63.9 6.2 16.0 11.7 8.7 9.0 6.7 7.0 0.6 12.0 16.1 14.3 14.3 18.3 2.7 3.3 5.1 6.9 1.1 7.6 2.4 7.5 7.0 6.3 7.0 8.8 15.4 1.6 9.4 5.4 7.1 5.4 2.1 10.2 0.1 8.4 14.2 2.8 11.9 2.1 6.5 3.6 6.2 5.2 0.5 16.2 3.1 2.7 0.5 0.6 12.4 16.1 7.4 2.6 7.9 4.8 0.5 2.3 4.1 11.3 18.7 0.3 8.6 2.0 7.5 5.8 2.7 4.2 1.7 10.6 7.9 2.3 3.5 9.9 8.7 7.4 2.7 4.6 6.4 9.9 17.9 7.5 19.9 4.9 3.4 4.2 0.1 15.8 6.1 5.2 1.8 1.5 5.1 5.3 3.3 7.6 2.7 5.5 5.9 3.3 2.3 4.4 3.6 2.4 1.1 6.9 0.0 5.6 2.4 7.4 8.6 12.6 8.3 6.2 2.6 11.4 1.9 9.8 7.0 17.9 16.2 4.7 10.4 11.1 0.5 8.9 10.2 1.4 11.4 3.5 0.0 0.9 3.3 2.3 0.4 15.8 1.7 0.0 3.8 1.7 7.7 7.3 2.3 0.8 2.5 4.8 0.0 28.8 12.5 1.1 15.0 5.1 5.0 13.6 4.9 5.2 8.9 0.0 14.2 1.5 0.4 6.5 10.5 8.7 2.1 12.9 0.1 10.2 4.3 14.4 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587045 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 15.5 17.6 19.6 17.3 26.3 10.3 21.6 27.5 27.3 21.1 16.4 15.7 15.8 12.5 23.1 23.6 15.2 15.5 17.6 22.2 20.5 17.5 15.9 15.5 20.0 22.2 22.9 16.4 25.0 13.5 25.8 25.6 23.6 20.7 21.2 15.3 12.4 17.0 23.3 24.3 18.7 14.7 19.4 23.0 23.3 14.7 13.8 21.7 28.2 20.3 10.8 21.9 17.2 18.9 14.2 15.9 19.4 17.7 18.2 22.1 13.6 7.9 7.0 20.5 17.6 15.0 20.1 14.5 16.0 18.5 14.4 18.2 9.0 7.6 17.7 10.2 17.2 12.8 8.5 12.9 12.4 24.6 9.0 13.7 15.8 9.7 11.9 15.8 17.5 12.2 16.6 15.3 14.0 17.2 16.6 13.5 15.6 31.5 14.5 20.6 9.7 8.1 14.8 16.8 12.4 8.9 14.0 36.9 8.6 12.1 8.9 10.4 14.8 11.1 7.7 12.0 16.8 7.7 31.1 12.9 11.7 7.4 10.7 14.8 12.9 11.5 7.7 18.0 19.2 17.2 15.5 12.7 19.4 15.1 17.4 16.8 14.2 14.5 14.4 15.9 10.5 16.5 16.0 12.5 18.2 17.7 9.8 22.1 13.6 19.6 26.3 27.5 27.3 20.5 17.5 22.9 16.4 20.7 21.7 14.9 24.0 20.7 17.4 32.3 22.8 28.8 12.7 16.0 10.3 15.7 25.5 27.6 6.6 16.6 2.6 20.3 9.3 0.0 18.3 26.6 23.5 24.4 12.8 17.9 21.1 27.0 11.6 30.7 26.3 2.2 24.7 25.3 20.3 27.9 15.6 18.9 15.5 7.0 38.5 13.1 21.1 19.4 19.1 24.6 24.0 32.5 40.5 25.5 15.1 23.0 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30433937-30461833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 104.6" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 133.3;Urothelial cells: 168.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol NA NA Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 28.0 7.6 3.6 15.6 4.1 104.6 26.1 1.5 2.6 8.2 8.4 2.7 11.3 3.4 11.5 16.5 13.8 19.5 15.3 20.1 4.3 2.9 6.3 7.6 29.0 33.7 4.3 2.0 9.8 3.6 2.8 4.1 27.5 8.3 7.9 6.8 9.4 6.1 18.4 8.6 15.3 9.6 23.4 9.7 25.6 10.7 6.7 3.6 2.4 7.0 13.2 17.2 13.2 15.6 19.6 13.8 23.7 16.8 12.4 7.8 4.0 8.0 7.2 2.0 4.2 10.5 8.8 9.3 2.0 12.1 4.5 5.4 5.0 18.8 5.3 5.2 4.3 4.4 15.2 4.5 1.9 1.6 12.3 2.3 9.9 12.3 16.0 8.9 3.1 24.4 11.0 1.1 4.5 0.9 4.5 2.0 0.1 4.4 8.0 0.7 4.6 0.1 11.8 0.7 4.3 2.6 0.6 1.6 3.0 4.4 16.4 0.2 0.8 7.2 6.2 0.9 5.7 2.1 6.6 0.1 2.8 2.4 9.9 0.3 12.1 11.3 1.6 4.0 13.4 0.1 17.9 7.0 23.7 7.8 12.0 4.3 9.6 1.7 4.9 6.6 19.6 0.1 3.0 16.7 12.4 16.8 13.8 0.4 4.0 3.6 4.1 1.5 2.6 4.3 2.9 4.3 2.0 8.3 3.6 35.7 41.7 14.7 46.9 103.8 13.9 7.1 5.1 25.4 13.6 3.5 0.0 23.9 1.7 25.2 0.4 36.9 5.2 0.0 9.8 71.1 77.1 32.5 71.4 3.0 109.0 0.0 11.5 14.1 86.6 0.0 7.8 94.5 40.5 78.5 5.3 5.0 17.6 17.5 3.9 2.4 1.1 6.5 75.4 0.0 0.7 74.2 133.3 52.3 5.8 168.4 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" 5 "Horizontal cells: 28.6;Urothelial cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.5 2.2 5.8 2.0 9.2 1.4 2.8 20.1 16.5 2.4 3.1 1.8 0.4 3.0 1.1 3.4 10.1 2.2 1.5 1.2 5.7 7.1 3.1 2.4 3.9 2.6 5.9 5.9 1.4 4.3 6.8 4.7 2.8 12.8 2.0 3.1 3.1 3.2 1.3 1.9 7.8 2.9 0.7 1.6 1.9 3.4 10.1 1.8 0.6 5.3 3.2 6.8 2.0 3.9 2.3 0.5 1.3 0.2 1.1 1.4 0.3 18.1 8.4 1.6 2.0 0.0 0.0 5.6 0.4 0.2 1.7 1.6 6.0 7.0 3.7 2.5 0.1 3.7 8.6 5.3 10.2 1.9 2.4 1.5 0.2 2.9 4.0 0.3 0.4 0.8 0.1 5.6 1.2 10.6 3.1 0.0 3.3 1.3 0.8 0.4 7.3 2.8 0.4 3.5 7.2 3.9 1.0 3.2 0.7 3.9 8.3 11.6 2.5 5.2 6.2 1.0 3.2 5.6 0.6 0.0 0.0 7.4 0.0 2.8 1.9 4.4 1.9 2.8 0.3 1.1 0.5 0.2 0.8 0.6 0.1 0.1 1.0 0.6 1.0 0.0 2.3 1.0 0.7 1.3 1.1 0.2 0.5 1.4 0.3 5.8 9.2 20.1 16.5 5.7 7.1 5.9 5.9 12.8 1.8 6.0 14.9 0.9 10.9 7.7 15.8 1.8 15.3 0.0 10.3 7.0 11.8 2.5 1.7 5.5 13.2 0.7 3.1 0.0 4.0 1.3 0.8 9.0 1.1 4.9 1.0 28.6 8.1 0.6 0.8 15.9 0.6 1.4 3.3 0.0 3.4 3.4 7.4 3.5 0.0 1.9 12.3 0.0 1.0 5.4 8.5 8.0 3.3 2.9 5.0 25.4 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.2;intestine: 16.9;lymphoid tissue: 39.2" "Cell type enhanced" "Detected in many" 14 "B-cells: 29.0;Rod photoreceptor cells: 58.2;T-cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 20.8;HDLM-2: 20.6;Karpas-707: 21.4;REH: 11.4;RPMI-8226: 12.9;U-266/70: 16.9;U-266/84: 16.6;U-698: 26.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 1.6 0.9 1.2 31.4 2.3 6.3 1.1 1.0 1.2 1.0 3.1 1.7 0.1 2.1 0.9 1.4 2.6 1.2 2.9 0.9 1.1 1.4 2.2 1.6 3.9 23.0 2.3 0.7 0.8 1.2 0.2 1.2 1.4 2.1 1.6 1.9 2.0 4.4 0.8 0.5 1.2 16.9 0.7 3.4 34.4 2.3 0.9 1.3 19.1 1.9 1.4 39.2 3.1 1.3 16.2 15.9 1.3 6.2 3.7 14.6 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.1 4.4 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.1 21.4 0.0 0.1 4.9 5.2 0.6 0.1 0.0 11.4 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 4.7 0.0 0.0 0.1 0.0 0.0 16.9 16.6 26.2 0.0 5.9 0.0 1.3 3.2 1.2 13.4 6.2 12.4 16.2 11.2 14.0 15.9 10.7 6.2 8.7 0.3 3.7 3.4 14.0 14.6 7.3 1.2 2.3 1.0 1.2 1.1 1.4 2.3 0.7 2.1 1.3 3.0 8.2 29.0 0.1 2.1 6.1 0.6 0.0 0.0 1.2 0.0 11.8 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.2 1.0 0.3 15.1 0.0 2.5 1.6 0.0 1.3 7.1 0.0 0.0 11.7 3.3 2.8 0.0 6.7 0.0 0.0 0.0 0.2 58.2 0.0 0.4 0.6 4.3 0.9 0.1 33.2 0.2 0.1 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784914-64803241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles NA NA Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 6.9 6.2 9.4 15.2 10.0 19.1 5.8 12.1 15.6 5.2 5.8 10.1 6.9 4.9 6.2 4.0 4.3 4.4 6.3 5.5 9.4 9.2 6.2 3.1 12.0 22.3 8.3 7.3 4.2 7.2 5.2 8.0 12.3 12.5 6.1 4.7 6.7 9.0 8.9 3.4 5.0 9.9 5.6 6.7 22.6 7.1 5.5 6.6 11.5 8.7 3.9 18.8 6.1 5.1 10.8 5.0 8.2 14.8 2.3 9.6 7.1 6.0 5.5 3.6 6.4 3.2 2.0 8.5 4.5 4.3 5.5 3.9 2.4 2.8 10.5 8.4 5.2 9.7 1.8 4.3 4.4 3.3 13.7 2.1 18.5 7.6 5.0 3.9 9.7 7.0 1.9 2.2 4.3 2.7 3.8 13.4 18.4 1.5 1.0 1.6 7.5 5.7 9.7 2.4 3.6 7.4 12.0 0.4 12.1 3.1 3.0 4.3 6.2 3.9 5.1 4.0 4.3 10.3 15.0 10.3 4.6 10.3 4.2 1.9 1.2 2.3 11.4 4.1 14.7 3.4 2.2 4.2 5.6 5.2 12.2 5.3 10.8 7.0 4.7 4.4 7.6 8.6 6.3 8.2 2.3 14.8 5.0 9.6 7.1 9.4 10.0 12.1 15.6 9.4 9.2 8.3 7.3 12.5 6.6 3.0 4.5 18.1 3.3 1.1 19.5 3.6 2.5 1.4 2.3 1.8 23.6 6.4 3.3 1.3 29.3 15.5 1.8 0.0 1.5 10.2 2.8 2.6 1.1 1.8 9.1 11.1 5.8 20.3 8.5 25.2 3.7 8.3 1.7 8.2 2.0 7.0 0.9 11.5 6.7 2.8 13.8 6.5 2.5 1.8 11.1 1.3 4.2 10.0 1.9 1.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437312 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 41.6;RT4: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 19.7 18.9 17.6 15.4 17.6 9.6 17.8 37.1 19.6 19.2 16.9 14.6 9.8 13.7 23.5 14.8 11.1 15.3 18.7 19.5 15.4 12.5 26.2 15.4 15.6 5.8 15.4 13.4 24.6 14.0 25.7 24.6 30.8 14.4 18.6 14.1 17.9 13.3 15.7 33.0 17.8 17.2 18.6 15.3 11.5 26.1 21.0 16.5 9.4 25.9 11.3 7.5 18.8 32.6 0.7 0.5 2.5 1.9 1.0 1.3 0.4 9.9 6.2 41.6 6.6 6.8 13.6 11.4 8.8 11.3 8.8 7.5 5.2 5.0 2.1 10.0 6.0 9.1 5.4 15.6 7.8 13.4 2.4 6.4 3.6 4.4 12.1 17.7 1.6 5.9 12.2 7.8 11.4 12.4 9.3 7.5 2.0 4.6 4.1 11.7 5.4 3.4 2.3 12.5 9.4 9.4 3.8 13.5 1.6 11.6 38.5 7.4 8.5 5.2 8.3 23.0 13.7 5.6 2.2 6.1 6.8 8.1 6.1 4.7 6.2 3.5 0.7 8.4 2.6 7.9 2.5 0.7 0.0 1.2 1.1 0.1 0.1 1.2 0.9 0.1 0.7 1.1 1.3 0.0 1.0 1.9 0.5 0.6 0.4 17.6 17.6 37.1 19.6 15.4 12.5 15.4 13.4 14.4 16.5 3.0 6.7 5.1 15.6 15.7 23.8 32.7 17.8 13.4 15.9 21.0 23.6 9.2 16.6 9.0 38.6 10.3 11.9 0.0 10.7 5.5 15.6 20.0 2.3 16.2 9.1 6.4 9.2 15.4 9.5 80.0 19.2 12.2 5.0 1.8 12.5 15.2 12.8 7.0 16.6 10.9 41.2 19.4 12.7 19.5 20.8 16.8 8.7 4.4 9.3 29.0 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 27.0 5.0 68.3 21.1 56.3 32.1 35.2 14.5 50.4 13.2 7.8 47.5 2.1 5.4 14.6 6.7 18.5 8.6 18.0 22.2 70.5 40.5 6.3 16.8 13.2 25.8 65.3 21.5 12.6 8.3 9.5 4.3 25.1 40.2 7.6 9.6 6.1 7.7 5.7 16.1 8.7 6.5 14.8 81.2 11.7 11.0 20.3 49.1 13.2 8.3 6.6 29.6 13.5 16.3 4.6 6.3 14.4 3.4 1.1 3.7 1.5 19.1 14.6 31.2 14.9 29.6 53.1 39.2 24.4 20.1 21.8 18.0 24.0 25.5 27.9 21.2 36.4 6.4 7.9 9.8 21.5 21.9 37.4 6.7 20.9 11.0 62.8 25.0 9.9 0.9 47.6 9.8 53.8 24.1 21.9 56.7 15.8 13.5 0.0 57.3 10.4 23.1 6.2 15.8 7.3 23.2 28.0 21.3 0.1 14.5 6.7 12.2 20.4 16.8 0.0 18.2 30.1 3.9 18.1 71.2 43.4 18.6 12.5 29.0 0.0 0.0 17.0 28.0 12.7 31.7 6.9 3.3 0.0 2.4 3.4 1.8 3.5 3.3 1.7 1.1 4.6 2.5 2.7 14.4 1.1 3.0 6.3 3.7 1.5 68.3 56.3 14.5 38.9 70.5 40.5 65.3 21.5 40.2 49.1 17.9 22.9 29.6 34.7 26.7 120.4 66.8 25.5 14.7 36.4 17.4 47.1 11.0 0.0 53.8 23.8 54.9 6.3 0.0 45.6 16.9 45.6 49.1 22.1 38.2 32.1 33.4 16.7 59.5 23.4 28.3 50.9 37.5 18.6 87.4 12.9 60.6 85.8 13.1 16.3 4.4 7.3 51.8 51.5 20.6 82.8 21.5 6.5 25.3 12.4 35.8 MAP4K5 "GCKR, KHS, KHS1" ENSG00000012983 "Mitogen-activated protein kinase kinase kinase kinase 5" 14 50418501-50561126 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 26.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 26.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036696, HPA078030" Uncertain Approved "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA036696: AB_10672362, HPA078030: " "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-3)" "unprognostic (4.13e-2)" "unprognostic (6.31e-2)" "unprognostic (2.24e-2)" "unprognostic (1.53e-3)" "unprognostic (7.34e-2)" "unprognostic (1.78e-2)" "unprognostic (3.71e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (2.02e-2)" 17.4 11.8 23.4 12.1 44.4 16.5 19.7 24.6 32.3 25.8 17.1 43.5 13.4 11.3 29.9 12.1 18.7 17.4 19.3 10.3 24.4 14.0 10.9 8.7 15.2 9.9 48.8 17.1 29.9 13.3 16.7 17.5 17.3 26.0 16.6 15.1 9.1 16.9 19.9 10.7 24.8 12.7 22.3 30.7 13.0 14.4 6.8 51.1 8.4 15.3 8.7 11.2 19.3 21.2 5.0 2.7 26.1 1.8 5.4 3.9 1.0 22.9 6.9 17.0 14.6 15.7 16.6 16.6 27.1 24.5 18.5 16.5 8.7 16.1 15.9 16.2 24.8 9.8 16.5 15.8 14.6 28.2 13.1 11.5 9.7 12.2 7.8 13.3 8.7 15.4 12.0 12.0 16.2 17.0 29.6 24.2 14.5 9.2 10.4 27.0 8.7 11.7 8.3 8.3 7.4 13.6 14.2 25.8 6.0 18.3 17.9 5.5 12.5 15.3 10.7 10.5 14.3 11.9 6.6 24.6 24.1 16.8 16.4 12.7 7.6 7.7 10.6 9.0 6.1 17.1 26.1 1.5 13.5 3.9 1.8 2.2 3.2 2.4 3.3 1.6 5.0 2.6 2.7 0.6 5.4 1.1 2.7 0.5 1.0 23.4 44.4 24.6 32.3 24.4 14.0 48.8 17.1 26.0 51.1 38.7 17.3 14.6 29.9 62.2 51.9 7.3 20.4 26.8 27.3 26.2 45.2 9.4 16.6 24.0 2.8 33.1 15.9 23.3 18.3 16.7 46.1 53.8 28.9 7.8 7.5 31.8 22.5 35.6 13.9 2.2 39.4 20.9 21.9 17.2 14.2 18.2 23.1 15.0 48.1 9.9 33.6 12.9 40.4 11.2 13.6 75.3 5.5 21.8 16.2 55.0 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21754500-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069" Approved NA NA 250000 "CAB004229: AB_627547, HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 16.1 21.1 32.9 18.3 80.3 20.2 13.6 31.0 54.5 18.6 18.5 23.2 9.6 13.7 17.4 10.6 25.7 16.9 14.9 22.8 32.4 23.4 21.7 16.4 19.9 16.6 18.4 23.6 16.0 19.8 27.4 10.9 17.2 27.6 16.4 19.9 14.2 15.8 17.8 28.2 17.5 15.1 22.8 20.4 19.8 17.2 24.2 21.5 19.5 23.0 11.1 21.4 17.7 15.3 2.5 3.2 13.5 4.9 7.0 13.7 2.5 19.7 12.5 16.1 9.2 19.1 19.2 6.1 21.8 20.4 19.6 19.0 9.9 10.5 10.9 10.9 29.2 18.0 18.8 18.9 17.4 25.6 44.0 17.7 19.8 11.7 11.6 15.7 27.8 20.6 14.3 14.0 23.7 21.9 15.4 26.7 11.9 81.1 12.5 23.9 8.1 18.0 6.1 6.1 26.8 12.3 19.8 39.7 2.9 11.2 16.2 13.1 7.3 23.6 14.2 12.7 16.7 10.7 9.4 23.3 16.4 21.4 18.8 13.8 12.0 14.6 17.0 15.5 13.6 17.7 1.0 4.0 5.8 13.7 4.6 3.9 2.0 2.9 4.9 3.2 2.5 2.8 5.1 13.5 7.0 4.9 3.2 2.7 2.5 32.9 80.3 31.0 54.5 32.4 23.4 18.4 23.6 27.6 21.5 44.7 30.2 28.0 22.1 53.3 23.8 34.6 63.7 21.4 33.0 48.8 51.1 18.0 16.6 24.0 33.2 31.2 46.6 23.3 33.6 18.2 31.5 37.5 93.2 59.4 47.7 27.0 57.3 57.7 88.6 9.9 30.2 59.7 38.8 15.4 44.2 32.3 39.5 28.8 41.8 37.6 21.0 32.3 32.2 70.0 47.7 54.1 16.0 95.8 30.7 34.8 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.3" "Cell type enhanced" "Detected in many" 16 "Ciliated cells: 92.3;Early spermatids: 179.3;Late spermatids: 303.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "AF22: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved NA NA "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favorable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favorable (5.57e-4)" 17.2 11.9 31.6 3.7 34.5 9.7 6.2 26.1 58.3 11.4 4.0 12.6 8.1 3.2 11.0 14.2 7.4 11.9 10.4 5.1 36.0 28.6 15.0 2.7 6.5 3.9 31.5 36.4 11.3 5.6 10.9 31.5 3.4 37.9 16.6 4.3 5.4 3.4 18.9 2.0 3.5 3.9 11.4 23.1 5.3 4.3 18.2 15.8 0.0 15.3 0.4 3.6 11.1 10.2 3.7 3.0 6.9 1.8 3.3 3.6 2.3 1.1 2.0 60.3 1.9 1.7 1.4 2.3 1.2 1.1 1.0 0.5 1.1 1.8 2.6 2.0 0.7 1.5 3.7 0.6 1.6 1.7 3.8 1.6 2.2 2.4 1.9 1.4 1.0 1.2 1.6 0.8 1.4 1.9 2.1 1.3 1.8 1.9 9.9 0.7 1.6 1.7 1.1 3.5 0.3 1.2 1.9 1.5 0.9 4.3 6.4 3.6 3.3 1.2 4.9 0.8 2.0 3.5 1.3 2.8 2.6 2.7 1.1 1.0 3.2 1.9 1.7 3.8 1.3 1.4 6.9 1.8 3.3 2.3 1.6 2.4 3.7 1.9 2.5 1.6 3.3 2.7 3.6 6.2 3.3 1.5 3.0 2.7 2.3 31.6 34.5 26.1 58.3 36.0 28.6 31.5 36.4 37.9 15.8 20.8 26.0 0.0 12.6 0.7 19.8 0.8 12.7 92.3 15.9 21.0 5.9 0.3 10.0 2.1 179.3 1.1 0.0 0.0 0.0 0.5 1.5 10.1 2.3 0.0 0.2 36.5 2.4 1.8 0.3 303.7 24.5 2.5 1.7 0.0 0.0 16.4 1.7 0.0 51.6 16.2 10.2 6.5 2.0 8.8 2.2 0.9 0.1 0.0 0.0 17.9 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Endothelial cells: 13.2;Ito cells: 14.7;Rod photoreceptor cells: 10.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 20.4 5.7 14.2 7.5 17.3 0.8 8.2 22.0 23.7 6.6 2.7 2.8 1.0 1.9 8.2 6.2 5.3 7.0 8.8 8.8 11.7 9.1 5.0 1.5 8.5 8.5 7.2 19.9 5.3 3.1 6.4 10.9 8.4 6.6 7.2 2.7 4.1 5.7 8.0 5.0 6.4 2.6 9.8 5.5 7.3 4.6 3.1 4.1 0.9 4.5 5.3 6.1 6.0 4.4 1.1 0.0 0.0 0.3 0.0 0.9 0.0 1.7 4.2 4.7 17.6 6.2 9.4 0.1 6.6 4.7 4.4 1.7 1.7 3.2 0.0 5.9 6.1 7.3 4.3 3.1 2.6 0.3 9.1 2.1 6.2 5.6 0.4 7.1 1.5 9.7 13.0 7.8 1.2 0.5 4.9 9.6 6.7 5.0 17.0 4.3 7.5 0.3 5.7 0.4 5.2 4.9 17.0 0.1 6.0 6.6 0.0 4.4 11.8 5.6 2.3 4.6 0.6 7.7 4.9 15.0 13.2 11.0 0.9 2.4 0.7 2.0 7.2 6.7 1.8 11.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.4 0.2 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 14.2 17.3 22.0 23.7 11.7 9.1 7.2 19.9 6.6 4.1 0.0 1.4 1.3 1.1 1.6 2.6 2.8 0.0 0.0 0.0 0.0 5.9 0.0 1.7 0.8 3.7 13.2 0.0 0.0 0.2 0.3 1.7 3.3 0.0 1.0 0.2 0.0 0.0 14.7 2.6 5.7 2.8 0.0 5.0 0.0 0.0 5.6 0.7 0.0 2.1 1.4 10.9 0.0 1.0 1.2 2.1 1.1 0.0 1.0 0.0 0.9 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261825 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 104.2" "Cell type enhanced" "Detected in many" 8 "Ito cells: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31 "NK-cell: 3.0" "Lineage enriched" "Detected in single" 31 "NK-cells: 3.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 35.4" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 3.0 1.6 4.5 2.1 4.5 1.0 1.8 9.0 7.0 2.1 1.4 2.1 1.6 2.0 5.4 5.1 3.3 2.9 2.4 5.1 3.9 3.6 2.5 1.0 2.1 2.0 3.5 5.7 3.0 1.4 1.2 7.0 2.3 2.6 2.9 1.1 2.2 1.4 3.7 104.2 0.9 1.5 4.2 2.6 1.6 1.5 1.6 2.4 0.0 1.3 10.8 1.1 2.4 1.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 10.4 6.4 2.5 7.5 5.7 6.3 3.5 8.0 6.9 13.4 8.5 9.3 3.3 19.6 10.9 8.8 8.0 7.0 11.1 1.6 2.6 5.6 15.6 12.8 19.5 11.5 18.1 12.0 25.4 13.5 2.9 3.0 0.0 7.3 15.2 1.8 11.3 18.2 6.2 5.7 0.0 16.0 7.5 3.5 10.5 18.3 6.7 19.9 7.9 1.4 8.6 2.9 6.2 0.2 9.9 1.9 3.4 14.0 7.9 13.9 12.5 3.0 5.0 4.2 3.2 10.5 3.5 11.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 4.5 4.5 9.0 7.0 3.9 3.6 3.5 5.7 2.6 2.4 0.0 5.6 1.3 0.4 0.7 5.1 7.8 2.5 1.4 0.0 0.0 0.0 0.3 1.7 0.4 0.3 9.5 0.0 0.0 0.0 1.8 2.8 3.0 10.4 1.0 4.9 1.6 1.7 22.1 2.8 1.3 6.1 0.8 0.0 1.0 0.0 5.1 0.6 0.0 3.5 6.5 1.7 6.5 2.4 0.2 9.7 0.5 0.3 1.0 0.2 0.0 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 143.1;Late spermatids: 214.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 16.5;T-cells: 27.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.2;RPMI-8226: 27.9;RT4: 28.9" "Region enhanced" "Detected in some" "cerebellum: 6.5" "Region enriched" "Detected in some" 15 "cerebellum: 59.9" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 6.5 22.0 2.2 5.4 4.0 2.9 6.8 2.8 7.3 6.8 18.9 0.5 36.8 18.8 1.9 10.3 41.1 2.4 12.0 1.2 1.7 1.8 6.5 2.8 9.6 11.2 0.8 3.8 3.9 24.6 18.8 12.4 10.5 2.5 6.8 16.0 2.4 20.7 26.3 0.9 28.6 37.7 2.1 0.8 5.9 12.2 23.7 1.1 5.0 13.8 16.0 18.5 7.3 13.9 16.5 0.1 5.2 0.3 2.8 27.8 6.7 19.6 0.1 0.3 0.2 1.2 5.7 2.7 1.6 0.2 0.2 0.5 16.3 19.4 4.7 1.2 1.5 2.8 15.2 0.0 46.2 0.4 12.0 5.2 0.1 0.5 16.2 2.0 0.1 1.2 4.9 16.4 3.0 0.6 2.3 3.0 0.5 0.3 5.3 0.5 10.3 0.1 1.2 0.1 19.4 0.3 11.6 0.2 27.9 9.0 28.9 19.6 0.3 1.7 0.3 0.1 0.6 22.0 2.5 4.1 1.4 0.2 0.5 0.3 0.3 7.0 1.4 0.0 0.5 0.1 5.2 0.3 4.5 16.2 0.0 10.5 10.8 11.6 13.0 0.1 16.5 10.6 11.9 3.9 2.8 0.0 0.0 27.8 6.7 2.2 4.0 2.8 7.3 1.7 1.8 0.8 3.8 2.5 1.1 26.8 24.1 11.5 34.8 24.3 0.8 1.6 22.9 1.4 22.7 27.9 5.9 41.4 13.3 48.4 89.5 2.3 143.1 0.0 102.6 8.3 3.2 28.0 2.3 1.6 35.8 0.0 63.0 0.6 6.1 214.3 6.6 6.4 16.9 22.6 80.8 1.5 76.0 89.2 9.2 7.9 2.2 0.0 1.0 6.1 1.5 46.5 27.0 20.2 93.7 47.8 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 32.1;neutrophil: 12.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 32.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 7100000 "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 21.5 20.6 11.7 18.4 15.5 49.9 20.7 26.5 18.1 22.0 20.5 12.5 11.9 16.9 38.8 12.1 24.0 18.9 16.0 16.4 9.3 9.5 16.0 29.8 21.5 29.0 12.0 11.3 17.7 18.5 15.0 27.2 27.3 10.2 23.4 18.3 17.0 16.7 16.5 21.2 25.6 22.5 26.0 10.6 35.5 18.2 11.1 10.3 34.1 20.9 17.6 20.8 25.0 30.0 2.3 4.0 32.1 4.9 3.0 2.8 2.1 18.5 10.2 11.0 17.7 25.1 25.0 24.2 19.4 25.3 23.0 24.0 24.9 9.6 15.0 19.3 21.3 11.0 13.3 18.1 16.8 24.1 16.9 14.5 34.7 14.5 20.8 13.8 21.9 21.0 17.6 16.4 16.6 16.5 19.2 26.1 26.0 19.2 18.9 15.7 8.8 22.4 26.3 6.7 11.4 10.2 26.7 17.9 13.9 16.2 25.6 8.3 7.0 17.5 13.1 20.3 14.1 15.4 40.9 18.3 20.7 12.0 13.0 17.7 9.3 21.2 15.1 9.4 43.2 16.9 32.1 4.9 3.0 2.4 3.5 2.8 1.5 2.2 2.6 4.0 2.3 2.5 2.4 12.3 3.0 4.7 1.9 2.6 2.1 11.7 15.5 26.5 18.1 9.3 9.5 12.0 11.3 10.2 10.3 29.8 11.5 18.2 10.6 14.2 19.3 23.5 7.6 16.0 19.4 17.4 29.5 38.2 1.7 12.1 2.6 20.2 25.7 0.0 9.9 14.8 20.9 9.0 20.7 39.4 22.3 11.1 16.1 21.5 58.1 3.7 22.7 30.0 10.1 19.8 22.5 12.2 17.6 20.3 25.1 14.0 24.3 12.9 11.5 6.3 7.7 16.7 20.0 23.5 15.6 8.8 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716259-143722458 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.9;epididymis: 27.6;fallopian tube: 29.5" "Cell type enriched" "Detected in some" 6 "Ciliated cells: 85.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons and medulla: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.2;HaCaT: 5.4;HeLa: 14.3;MCF7: 13.9;T-47d: 12.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 0.6 0.1 3.6 0.3 8.1 0.1 1.1 0.2 2.1 4.5 0.4 8.7 5.2 0.5 2.2 27.6 1.3 29.5 0.4 1.1 5.4 4.6 3.9 0.2 7.4 0.5 0.2 1.5 4.7 2.0 9.1 4.2 0.6 26.9 0.9 0.4 1.6 3.0 2.4 0.2 4.9 0.7 0.5 0.4 0.5 0.9 7.3 2.4 0.1 8.4 0.5 0.4 0.5 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.7 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 7.2 0.0 1.3 0.0 0.0 5.4 0.1 0.2 0.0 1.1 1.6 0.0 14.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.3 2.7 0.0 0.0 13.9 0.0 0.0 2.0 1.2 1.1 0.0 3.0 0.4 0.9 1.3 4.0 4.0 0.0 2.8 0.0 0.2 12.5 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 8.1 0.2 2.1 5.4 4.6 0.2 1.5 26.9 2.4 0.0 8.3 0.0 0.2 0.3 0.0 0.8 0.0 85.6 13.6 0.0 0.0 0.0 0.0 0.6 12.6 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.7 0.3 0.1 0.0 0.1 0.0 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 255.2;Enterocytes: 275.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 25.1;neutrophil: 11.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 25.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 24.9 18.5 63.3 15.3 43.2 15.6 21.1 24.8 52.0 21.3 45.1 30.4 6.3 39.7 24.2 11.4 44.1 28.7 25.6 21.2 37.1 34.0 13.4 8.8 23.3 13.1 33.8 27.4 32.7 13.0 26.1 15.2 27.6 27.6 20.1 36.7 26.2 17.1 18.3 13.9 18.7 49.2 24.0 27.8 15.9 33.7 11.6 19.5 8.4 20.5 18.7 26.0 18.2 22.2 1.4 1.5 25.1 2.7 0.8 3.1 1.4 14.0 7.7 16.4 9.2 41.2 54.6 9.2 10.5 26.0 16.6 19.9 9.1 28.2 14.1 10.4 29.3 19.2 5.2 13.7 12.3 16.3 26.7 15.9 4.3 8.5 15.3 41.4 3.2 12.1 33.7 7.2 19.0 8.6 25.3 42.2 15.5 5.9 18.2 22.0 36.8 14.5 5.0 4.3 28.6 6.7 17.2 9.7 31.7 15.2 8.9 14.5 10.3 6.0 21.1 6.1 13.8 13.8 7.7 29.9 11.0 9.5 12.5 3.6 20.7 9.4 7.2 22.0 6.8 7.7 2.4 2.7 25.1 0.9 1.9 1.4 1.3 2.1 1.6 1.4 1.4 1.5 1.6 11.3 0.8 1.0 1.5 3.1 1.4 63.3 43.2 24.8 52.0 37.1 34.0 33.8 27.4 27.6 19.5 20.8 20.3 9.0 19.0 8.8 28.0 12.7 15.3 20.1 7.9 8.7 21.6 66.6 19.9 31.0 255.2 49.5 275.3 0.0 54.5 107.4 25.7 11.8 2.3 6.4 38.5 7.9 52.6 52.8 25.3 107.0 30.0 18.9 21.9 27.9 135.6 38.1 77.0 98.1 25.8 18.2 32.7 19.4 18.6 10.5 17.5 11.5 28.3 13.1 63.5 18.0 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560078-50731824 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.4;brain: 33.4;parathyroid gland: 43.5" "Cell type enhanced" "Detected in some" 15 "Cardiomyocytes: 20.1;Early spermatids: 20.2;Late spermatids: 42.4;Muller glia cells: 55.0" "Group enriched" "Detected in many" 5 "glioma: 15.2;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.0;HeLa: 4.5;NTERA-2: 3.0;SCLC-21H: 15.7;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" NA NA "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 1.9 26.4 16.9 1.1 33.4 0.9 1.8 15.9 23.9 1.4 2.6 9.5 3.8 1.6 1.8 4.5 3.5 1.5 3.0 16.9 13.0 14.3 4.5 7.0 3.5 0.9 17.1 9.1 4.2 2.5 43.5 8.3 3.7 20.5 5.3 1.8 4.1 1.8 12.4 1.7 1.0 1.9 5.2 11.8 1.1 1.3 3.5 12.4 1.7 7.8 0.0 0.9 2.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.5 1.4 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.9 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 15.7 3.8 0.1 1.1 2.6 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 33.4 15.9 14.5 13.0 14.3 17.1 9.1 20.5 12.4 8.9 0.0 0.0 0.1 0.0 11.0 20.1 2.5 0.0 0.0 0.0 0.0 3.6 5.0 1.0 20.2 0.0 0.0 0.0 0.0 0.3 0.4 0.8 0.0 0.8 0.3 4.8 0.0 0.0 0.0 42.4 0.9 0.0 0.0 0.0 0.0 55.0 0.5 0.0 1.4 0.0 0.6 0.0 1.0 0.6 0.6 0.0 1.5 0.0 0.0 0.0 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067372 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Supported Cytosol NA NA Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868, HPA047825: " "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 11.8 7.4 14.4 10.9 23.2 25.6 13.7 33.0 24.5 16.3 18.7 12.5 9.3 16.3 15.9 13.3 32.3 8.2 17.0 9.1 13.3 15.9 14.4 32.6 12.6 9.4 13.1 16.8 11.5 8.5 12.2 15.3 13.9 23.8 10.5 18.1 9.5 17.9 11.4 27.1 24.0 26.2 17.8 14.2 9.2 15.7 25.7 13.0 11.7 13.4 22.7 12.4 18.9 22.4 4.9 4.2 3.0 4.5 6.5 7.9 3.6 8.7 11.8 23.3 8.9 7.2 11.9 17.1 12.6 12.7 11.6 13.7 14.1 5.3 12.6 8.8 16.1 17.0 12.4 17.9 23.9 15.9 7.7 5.6 18.8 7.0 22.4 17.5 14.0 40.2 12.7 44.0 14.0 36.5 12.4 10.9 8.7 24.3 21.6 14.8 19.8 9.8 11.1 8.3 10.9 5.7 8.6 15.0 20.3 11.1 36.9 11.5 10.8 10.1 8.3 18.3 33.7 7.5 20.9 10.8 13.9 15.0 9.0 16.7 11.2 32.9 15.7 17.2 20.6 17.0 3.0 4.5 1.2 3.8 4.3 4.7 4.9 5.6 4.3 4.2 2.6 5.4 3.8 0.6 6.5 2.8 1.9 7.9 3.6 14.4 23.2 33.0 24.3 13.3 15.9 13.1 16.8 23.8 13.0 26.8 29.8 23.8 84.4 99.5 34.6 20.2 22.9 24.1 29.6 15.7 15.7 14.3 14.9 31.8 133.3 22.8 95.4 0.0 43.1 33.7 40.4 80.6 139.2 47.8 25.7 31.8 29.7 16.5 30.7 167.7 21.0 26.7 28.7 11.8 32.2 25.1 52.1 31.6 22.3 30.5 21.1 19.4 21.7 56.4 75.8 96.7 27.7 17.0 19.8 153.6 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Sertoli cells: 25.8;Spermatocytes: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 24.1;SuSa: 29.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.5 15.0 6.4 7.3 7.6 9.2 11.8 12.5 7.9 13.4 15.3 7.2 6.0 9.2 13.1 14.1 17.3 9.4 11.8 8.2 5.9 4.7 10.8 4.8 9.9 9.2 8.2 5.2 25.4 5.7 7.3 7.5 12.5 6.7 14.0 6.9 10.5 7.8 12.3 7.5 13.1 11.2 13.8 7.1 13.2 8.0 13.3 7.5 4.5 8.6 11.3 10.6 12.7 15.9 2.2 2.6 11.5 7.4 5.5 4.7 3.0 3.6 5.8 4.8 3.7 24.1 10.1 5.6 5.0 4.6 6.9 6.4 6.7 0.6 2.2 4.0 8.6 5.1 4.1 5.6 4.6 4.3 3.8 4.3 1.0 4.1 2.9 10.4 0.9 3.7 10.6 3.2 10.5 3.7 6.0 5.1 4.3 1.9 0.8 6.9 2.4 7.4 3.9 5.5 3.7 3.8 4.0 7.0 1.5 2.3 2.0 2.2 6.4 5.1 0.5 2.5 29.6 3.1 1.2 2.8 7.4 5.5 8.2 3.4 1.4 2.1 0.6 8.6 0.9 4.5 1.0 3.6 11.5 4.7 7.4 2.5 2.2 2.2 4.1 2.6 1.4 2.1 2.6 1.3 5.5 6.5 1.7 1.0 3.0 6.4 7.6 12.5 7.9 5.9 4.7 8.2 5.2 6.7 7.5 6.0 3.5 6.2 5.5 4.8 2.0 1.7 0.0 1.4 2.3 5.2 2.0 4.8 5.0 7.1 6.3 7.1 9.0 0.0 5.3 6.9 8.3 5.5 2.3 1.3 6.7 0.0 10.3 6.7 6.7 5.9 10.6 6.3 3.3 2.8 5.7 14.5 6.2 13.5 11.0 3.0 2.0 25.8 8.6 31.4 10.6 3.8 4.2 4.4 6.1 5.2 MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396" Approved NA NA "CAB004463: AB_675868, CAB069396: AB_1619977" "unprognostic (7.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (8.66e-4)" "unprognostic (4.23e-2)" "unprognostic (5.98e-2)" "unprognostic (4.31e-3)" "unprognostic (2.33e-1)" "unprognostic (6.06e-2)" "prognostic favorable (8.66e-4)" "unprognostic (1.58e-1)" "unprognostic (9.95e-2)" "unprognostic (1.85e-2)" "unprognostic (1.01e-3)" 13.4 11.7 15.3 11.5 18.5 13.3 22.1 33.6 35.2 15.2 13.9 12.9 19.5 16.7 17.1 10.8 16.1 12.4 15.1 11.2 20.0 18.0 20.1 23.6 11.7 12.0 15.9 16.7 18.9 15.3 12.7 23.7 12.2 23.6 13.0 14.3 12.4 17.2 15.9 18.9 10.8 17.7 14.6 13.7 9.6 12.2 23.4 12.2 20.5 22.3 9.0 13.8 11.8 13.0 4.5 4.3 5.2 4.3 4.7 5.7 3.5 16.0 4.3 14.5 8.3 5.6 6.6 11.3 24.2 16.6 14.5 11.9 5.0 16.6 5.8 6.6 13.5 7.6 9.8 5.0 9.3 19.0 34.7 8.3 8.3 5.0 6.8 9.2 14.2 9.8 5.5 10.7 10.8 21.4 8.6 13.3 16.1 13.3 10.7 9.4 4.7 17.3 7.6 9.1 5.8 3.2 11.4 15.0 5.8 8.9 6.2 24.4 19.4 9.4 7.9 10.9 9.8 8.6 6.8 11.4 10.8 26.0 8.2 18.2 3.4 8.3 11.8 7.5 15.1 6.2 0.0 3.3 3.0 4.1 2.8 4.7 4.5 5.7 5.0 3.3 2.9 5.6 3.9 5.2 4.7 4.3 4.3 2.9 3.5 15.3 18.5 33.6 35.2 20.0 18.0 15.9 16.7 23.6 12.2 3.0 11.3 7.8 38.8 39.8 58.6 8.3 22.9 14.7 14.8 7.0 29.5 11.7 10.0 24.2 142.4 17.8 21.0 0.0 22.3 5.8 15.8 35.2 11.5 16.3 8.8 66.7 29.7 8.6 9.9 66.1 13.6 16.2 20.3 31.5 12.5 21.2 25.4 15.0 9.6 19.2 34.4 6.5 25.8 22.7 25.1 32.0 13.2 11.5 11.5 38.7 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "basophil: 13.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.2" "Cell line enhanced" "Detected in all" "HDLM-2: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008910 Enhanced NA NA "CAB008910: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 10.3 12.4 22.9 9.6 31.8 10.3 11.4 48.7 41.4 10.8 12.4 10.6 4.7 10.1 8.7 9.5 8.7 8.8 7.8 14.0 24.3 25.0 12.2 9.7 10.8 10.0 22.0 21.0 8.5 25.9 16.3 8.8 10.9 29.4 11.7 15.3 7.0 9.9 13.1 20.5 6.3 10.4 11.4 16.8 8.6 12.3 9.4 10.3 7.1 15.4 5.1 11.3 9.9 7.3 1.4 1.4 13.2 2.4 1.3 3.1 0.3 17.2 14.3 12.6 15.8 12.5 14.1 27.2 16.6 14.8 14.0 14.1 18.7 12.3 18.5 28.7 17.6 30.8 13.3 13.0 27.9 16.5 69.4 12.5 7.7 15.9 13.3 9.5 15.9 13.5 10.3 12.5 13.6 13.2 14.6 16.6 14.5 8.4 13.4 19.0 22.6 15.8 6.6 8.8 21.4 8.5 15.3 21.5 8.8 10.6 16.5 14.6 10.3 19.5 19.0 13.2 16.4 19.3 13.8 11.9 16.8 16.9 23.6 24.8 9.7 11.4 12.6 17.8 14.9 11.1 13.2 0.6 2.5 2.0 1.3 2.0 1.0 1.5 1.8 1.0 1.4 1.0 1.2 0.9 1.3 2.4 1.4 3.1 0.3 22.9 31.8 48.7 41.4 24.3 25.0 22.0 21.0 29.4 10.3 29.8 11.8 11.5 6.1 9.0 18.3 20.7 10.2 5.3 10.3 8.7 15.7 12.1 5.0 7.1 0.9 15.7 13.5 0.0 13.9 18.8 9.9 10.0 11.5 15.3 10.3 12.7 16.0 13.5 17.2 2.3 9.8 12.8 5.0 10.0 17.1 10.4 10.9 11.5 12.7 9.2 14.2 12.9 7.2 15.9 17.0 9.9 14.9 8.6 14.5 7.3 MAPKAPK2 ENSG00000162889 "Mitogen-activated protein kinase-activated protein kinase 2" P49137 1 206684944-206734283 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in all" 6 "dendritic cells: 18.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome NA NA Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: AB_2679367, HPA063708: AB_2685100, HPA064435: AB_2685263" "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 23.0 25.3 11.6 21.2 15.7 58.6 23.9 11.1 14.5 19.3 25.6 17.2 14.5 25.7 20.0 18.5 23.5 17.3 26.0 89.2 12.3 8.7 33.7 26.7 26.7 21.5 16.7 6.5 23.3 19.1 16.9 22.8 13.6 15.7 20.2 14.4 17.8 19.8 14.4 62.9 18.3 32.9 18.3 14.6 37.7 23.1 21.3 14.6 26.9 24.3 25.2 28.2 22.9 46.1 1.1 18.7 3.2 1.1 2.3 1.6 0.5 21.2 8.4 11.7 13.2 34.6 20.3 14.6 14.8 33.7 22.7 21.4 16.1 10.4 10.2 10.4 29.9 14.2 16.1 8.7 15.8 16.3 11.9 6.6 17.2 10.5 10.3 26.7 25.4 57.6 28.0 20.2 21.8 24.1 18.9 18.5 13.9 19.8 46.7 18.3 26.4 10.2 18.4 13.5 7.5 11.8 26.2 24.6 3.3 17.1 13.1 9.4 12.1 17.5 29.6 20.5 22.8 14.4 24.7 17.6 20.5 17.3 23.7 20.2 60.9 54.0 8.3 23.2 15.5 6.7 1.1 0.7 1.4 1.6 1.1 1.5 1.0 1.2 1.5 0.6 1.1 0.6 1.1 3.2 2.3 1.0 18.7 1.4 0.5 11.6 15.7 11.1 14.5 12.3 8.7 16.7 6.5 15.7 14.6 50.6 53.7 28.9 47.2 75.9 11.3 97.2 40.8 6.7 29.6 29.6 19.6 5.0 13.3 28.0 71.3 26.3 27.4 23.3 50.4 7.0 28.6 55.9 34.6 34.4 22.4 0.0 59.3 21.5 27.7 20.1 21.0 27.9 32.1 12.6 32.0 17.7 50.5 21.2 16.3 21.0 14.8 25.8 48.7 11.8 4.1 63.0 13.8 37.4 24.1 68.1 MAPKAPK3 "3pK, MAPKAP3" ENSG00000114738 "Mitogen-activated protein kinase-activated protein kinase 3" Q16644 3 50611520-50649297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.7;skeletal muscle: 70.1" "Cell type enhanced" "Detected in many" 9 "Cardiomyocytes: 193.9;Hofbauer cells: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 30.2;eosinophil: 23.0;intermediate monocyte: 50.0;myeloid DC: 27.1;neutrophil: 20.5;non-classical monocyte: 61.4;plasmacytoid DC: 16.9" "Group enriched" "Detected in all" 5 "dendritic cells: 27.1;granulocytes: 23.0;monocytes: 61.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 8.9 16.1 5.6 9.3 7.2 30.4 6.3 1.9 6.2 5.5 9.5 7.1 7.5 9.9 5.5 8.6 16.8 5.1 8.5 86.7 4.8 3.7 17.9 11.9 11.0 15.1 7.2 4.1 8.7 24.2 11.2 9.0 9.0 6.0 7.6 6.7 10.9 12.4 9.2 70.1 17.6 12.0 5.2 5.9 12.5 9.0 4.0 5.2 25.9 22.6 40.9 14.3 6.1 7.5 3.0 27.1 23.0 61.4 7.3 6.4 19.5 23.4 7.3 3.0 8.6 4.6 11.7 6.9 5.7 8.2 8.8 7.5 11.3 21.9 9.4 5.8 19.1 21.9 8.4 20.9 22.5 7.9 20.8 5.0 49.5 10.3 10.2 9.3 35.6 26.4 9.3 14.0 20.5 28.0 8.8 7.8 16.8 13.9 6.2 18.5 9.5 15.1 35.9 11.4 8.2 30.0 6.7 7.3 14.2 41.0 13.5 5.7 4.0 5.1 14.5 6.5 5.3 9.1 22.1 5.6 7.0 16.0 36.0 14.1 4.2 7.7 7.8 37.0 56.1 2.8 6.4 30.2 23.0 5.5 50.0 5.4 3.0 6.2 6.4 27.1 1.8 4.9 5.5 20.5 7.3 61.4 16.9 5.2 19.5 5.6 7.2 1.9 6.2 4.8 3.7 7.2 4.1 6.0 5.2 8.9 9.4 7.5 19.5 10.1 0.9 193.9 10.2 6.7 6.8 10.4 0.0 5.0 54.7 35.3 28.4 6.7 23.1 0.0 26.4 5.7 11.0 21.5 35.7 10.9 91.5 0.0 5.8 4.9 48.9 60.2 6.6 40.9 6.8 46.9 13.9 10.8 54.8 8.6 3.2 28.5 2.3 25.8 11.7 3.4 4.3 17.7 4.2 18.7 27.9 30.1 MAPKAPK5 PRAK ENSG00000089022 "Mitogen-activated protein kinase-activated protein kinase 5" Q8IW41 12 111841978-111902238 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 20.7 26.2 21.4 17.5 26.4 24.1 21.7 23.7 28.3 17.3 28.8 26.1 21.9 26.3 25.8 22.8 20.8 17.5 22.7 20.7 17.7 15.2 21.7 21.5 18.9 19.4 22.3 20.4 21.3 24.5 19.8 20.4 21.0 17.3 18.7 32.9 23.6 23.3 20.5 33.2 23.0 28.4 21.1 18.0 18.4 19.8 16.7 22.0 19.3 20.5 15.1 19.3 19.9 16.5 4.9 4.1 3.2 11.4 3.9 6.8 2.5 14.9 19.8 19.2 16.1 13.9 14.1 29.3 15.0 18.1 23.0 16.0 25.6 12.3 22.6 11.1 17.6 13.7 14.9 25.2 15.7 21.6 15.0 13.8 20.1 13.8 20.5 16.8 25.2 14.2 14.8 22.6 22.0 26.2 17.5 16.9 20.6 27.7 8.9 16.8 16.8 25.0 39.9 27.3 36.8 14.0 24.8 14.0 21.7 18.3 21.7 23.7 20.1 17.0 29.0 20.8 18.3 23.5 28.9 14.7 13.1 13.2 13.4 18.7 18.3 22.4 26.7 15.9 18.4 18.5 1.3 4.8 3.2 6.5 3.5 3.5 4.9 4.3 4.7 3.3 4.0 6.8 5.1 2.5 3.9 11.4 4.1 6.6 2.5 21.4 26.4 23.7 28.3 17.7 15.2 22.3 20.4 17.3 22.0 3.0 17.2 13.8 19.4 18.2 45.9 15.7 22.9 9.4 15.9 3.5 39.3 26.2 11.6 25.6 11.1 15.5 36.7 0.0 25.7 28.0 17.4 20.5 2.3 11.1 17.5 22.3 35.2 16.5 15.8 5.6 14.4 16.6 8.5 24.4 39.9 19.2 27.7 28.8 16.6 16.8 34.7 19.4 17.9 18.0 36.8 18.6 25.2 22.3 30.8 24.3 MARCH1 "FLJ20668, MARCH-I, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.4;lymphoid tissue: 32.4" "Cell type enhanced" "Detected in many" 11 "B-cells: 128.6;Cone photoreceptor cells: 184.6;Kupffer cells: 192.5;Macrophages: 105.3;Rod photoreceptor cells: 172.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 95 "classical monocyte: 16.8;eosinophil: 9.9;intermediate monocyte: 17.0;memory B-cell: 18.5;myeloid DC: 18.1;naive B-cell: 15.7;non-classical monocyte: 17.2;plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 9.6;U-266/70: 9.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014600 Uncertain NA NA "HPA014600: AB_1853573" "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 7.7 4.2 11.6 20.5 19.7 3.9 4.0 3.1 14.5 3.7 3.9 8.5 0.1 4.4 3.9 4.6 3.6 4.2 5.9 2.6 12.6 10.1 3.0 4.5 8.3 28.5 17.3 6.3 4.2 4.1 1.5 4.1 10.2 13.5 3.5 5.1 2.4 4.6 1.8 1.6 4.9 9.0 6.5 24.4 32.4 4.1 2.3 17.9 2.6 3.2 1.4 24.6 9.0 4.2 18.5 18.1 9.9 17.2 0.1 0.0 6.6 0.8 0.7 2.9 1.7 0.0 0.0 1.9 1.2 0.1 0.0 0.0 1.6 3.3 9.6 3.6 0.0 0.4 1.4 0.0 0.0 0.0 1.0 1.0 6.8 3.7 0.6 0.0 4.1 2.2 0.0 0.0 0.0 0.2 4.0 0.0 1.9 2.5 5.0 3.3 1.0 2.3 2.6 3.6 0.3 1.3 2.7 0.5 0.7 0.1 1.6 1.5 1.3 0.9 1.5 0.5 2.2 4.0 0.7 3.1 1.1 2.0 0.7 2.3 9.8 3.3 2.7 1.4 2.1 1.5 0.0 16.8 9.9 0.0 17.0 0.0 18.5 0.0 0.0 18.1 15.7 0.0 0.0 0.1 0.1 17.2 6.8 0.0 6.6 11.6 19.7 3.1 12.5 12.6 10.1 17.3 6.3 13.5 17.9 0.0 2.7 128.6 0.0 1.5 24.7 2.4 0.0 1.4 4.5 3.5 184.6 0.3 0.0 0.0 4.6 1.1 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.9 43.0 11.1 0.0 3.1 192.5 1.7 0.0 105.3 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.1 172.3 12.9 0.0 0.6 1.5 0.9 0.7 0.8 0.0 0.0 MARCH10 "FLJ35757, MARCH-X, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 80.2" "Group enriched" "Detected in some" 7 "Early spermatids: 371.3;Late spermatids: 1043.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Cell line enhanced" "Detected in some" "BEWO: 3.9;EFO-21: 7.3;HSkMC: 3.2;SCLC-21H: 12.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" 0.2 0.1 0.7 0.2 1.6 0.0 0.1 0.1 0.3 0.5 0.1 1.9 0.6 0.0 0.3 4.8 0.1 7.9 0.1 0.1 1.0 1.0 0.6 0.1 1.4 0.1 0.2 0.5 1.0 0.1 0.3 4.5 0.1 1.8 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 80.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.0 0.6 3.4 0.3 0.1 0.0 0.2 0.0 0.0 0.2 3.9 1.7 0.2 1.2 0.3 0.0 0.1 0.0 7.3 0.5 0.1 0.0 0.0 0.4 1.4 0.0 0.0 1.3 0.7 0.0 1.5 0.0 0.0 3.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.9 1.5 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.2 1.1 0.0 12.7 0.0 0.0 0.7 0.1 0.5 0.2 0.0 0.0 0.0 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.7 0.3 0.7 0.1 0.6 1.8 0.0 0.6 0.0 0.0 0.7 0.3 0.7 1.6 0.1 0.3 1.0 1.0 0.2 0.5 1.8 0.3 3.0 1.0 0.0 0.0 0.1 0.0 0.3 0.0 105.7 15.9 3.5 0.0 0.1 44.7 0.0 371.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.6 0.0 1043.9 4.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.5 0.0 42.4 10.6 0.0 0.1 0.5 0.0 0.0 MARCH11 "MARCH-XI, RNF226" ENSG00000183654 "Membrane associated ring-CH-type finger 11" A6NNE9 5 16067139-16180762 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 42.1" "Group enriched" "Detected in some" 7 "Early spermatids: 83.9;Spermatocytes: 30.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 44.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (9.91e-3)" "unprognostic (1.08e-1)" "unprognostic (2.98e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (1.52e-1)" "unprognostic (3.55e-2)" 0.4 1.1 1.8 0.3 3.4 0.3 0.4 3.7 3.7 0.3 0.4 0.0 0.0 0.3 0.4 0.3 0.3 0.3 0.3 2.2 2.0 3.2 0.5 0.5 0.4 0.3 1.5 2.0 0.5 1.0 0.3 6.8 0.4 2.1 0.6 0.4 0.6 1.4 0.3 0.3 0.3 0.4 0.3 0.5 0.3 0.4 42.1 0.0 0.0 0.3 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 44.3 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.4 3.7 3.7 2.0 3.2 1.5 2.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 5.9 2.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 2.4 6.5 0.0 30.3 1.4 0.0 0.0 0.0 0.0 0.0 MARCH2 "HSPC240, MARCH-II, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.48e-4)" "prognostic favorable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favorable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favorable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" 37.7 12.4 30.7 13.5 28.3 17.5 23.9 8.6 39.1 9.8 29.8 20.7 9.7 11.2 12.5 39.0 19.3 10.0 11.4 38.9 23.5 21.9 11.0 17.9 18.2 15.0 30.8 19.8 8.2 10.0 10.5 11.3 13.9 20.2 16.0 10.3 12.7 13.4 21.8 46.9 12.7 11.7 28.5 27.8 18.9 13.3 8.6 13.3 8.4 21.3 14.1 10.0 20.4 9.7 3.6 26.5 20.4 14.6 3.7 7.3 10.1 5.6 7.2 3.2 15.1 19.9 6.5 5.5 6.1 7.5 4.9 5.1 3.5 2.6 2.2 18.0 13.1 6.5 4.0 4.2 8.6 3.8 11.1 9.9 17.0 3.3 7.8 10.8 2.5 25.7 7.8 9.9 4.7 4.2 7.1 19.2 9.0 2.4 12.5 3.8 10.7 3.4 8.1 6.8 6.8 17.4 5.4 1.0 5.6 11.3 6.7 1.6 9.1 0.4 6.6 11.5 11.6 5.0 5.4 19.3 6.9 4.2 22.8 5.1 11.2 13.3 2.5 11.2 5.1 5.2 20.4 10.0 15.4 5.7 14.6 5.9 3.6 5.9 4.6 6.7 3.5 4.0 5.4 12.5 3.7 12.8 26.5 7.3 10.1 30.7 28.3 8.6 39.1 23.5 21.9 30.8 19.8 20.2 13.3 3.0 10.9 4.5 0.0 6.6 10.7 38.1 7.6 2.7 3.4 19.2 2.0 6.6 33.2 0.0 8.1 27.0 13.6 23.3 0.0 9.3 10.5 0.0 12.7 24.6 57.4 22.3 11.6 47.9 48.6 36.4 8.6 19.4 23.6 0.0 5.5 17.5 0.0 7.4 11.0 43.4 7.7 12.9 20.6 5.4 8.5 11.3 4.8 18.1 4.6 0.0 MARCH3 "MARCH-III, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030808 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Muller glia cells: 52.5;Spermatocytes: 61.1;Syncytiotrophoblasts: 82.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 8.8;naive B-cell: 13.1" "Lineage enriched" "Detected in many" 5 "B-cells: 13.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 25.1;HUVEC TERT2: 16.7;TIME: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 11.3 6.0 5.6 11.0 9.4 6.6 6.2 5.3 4.8 2.0 10.8 8.2 0.5 2.4 3.7 3.6 3.4 3.2 10.4 15.2 7.8 6.8 2.0 1.9 5.2 5.2 9.5 2.3 4.0 5.0 1.7 10.8 4.0 12.3 2.9 11.8 9.7 11.2 1.1 11.9 11.5 5.2 6.5 16.0 3.7 5.5 14.2 7.6 2.1 3.6 3.4 5.8 6.5 6.7 13.1 0.7 2.5 0.4 1.9 2.6 0.7 0.3 1.2 2.4 1.3 2.1 2.1 0.8 8.5 3.6 6.9 10.2 1.1 0.5 2.3 0.8 1.3 1.5 0.7 3.0 1.5 9.8 0.5 2.7 7.2 2.0 1.1 3.5 2.9 1.8 1.5 0.5 25.1 3.0 1.6 16.7 0.3 3.0 0.4 5.7 0.8 0.3 1.3 2.0 1.8 2.8 0.9 9.6 0.6 0.5 1.2 0.7 0.5 2.0 0.3 1.0 1.2 1.7 3.0 20.3 1.3 1.1 7.9 0.9 1.1 1.3 1.3 5.1 2.3 1.2 0.0 0.2 2.5 0.5 0.4 0.1 8.8 0.6 0.3 0.1 13.1 2.4 0.5 0.8 1.9 0.3 0.7 2.6 0.7 5.6 9.4 5.3 4.8 7.8 6.8 9.5 2.3 12.3 7.6 3.0 3.4 18.2 0.0 5.4 18.3 12.9 17.8 1.4 3.4 0.0 2.0 33.6 0.0 0.0 33.1 6.0 15.5 23.3 0.0 3.1 6.7 0.0 24.3 0.8 7.7 35.0 14.3 11.6 3.5 9.8 0.3 2.0 3.3 0.0 23.4 52.5 0.0 44.4 1.8 0.2 25.6 0.0 0.9 61.1 12.7 7.8 82.5 5.1 21.9 0.0 MARCH4 "KIAA1399, MARCH-IV, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372027 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 16.6;pituitary gland: 13.1" "Cell type enriched" "Detected in some" 6 "Intestinal endocrine cells: 15.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 33.8;fHDF/TERT166: 21.5;TIME: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014348 Approved NA NA "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.7 2.9 7.0 0.7 11.9 0.7 0.6 1.0 16.6 0.6 1.1 0.3 0.0 1.5 0.7 0.7 0.6 2.5 0.6 0.6 5.8 5.6 0.6 0.6 0.8 0.6 2.0 4.8 0.6 1.5 0.6 13.1 3.1 3.4 0.7 1.2 0.1 0.6 0.6 0.6 0.7 1.4 0.6 1.6 0.6 5.1 0.7 1.1 0.0 0.6 0.0 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.6 1.2 0.0 0.0 0.1 0.8 0.0 33.8 11.6 7.3 2.6 0.0 0.5 0.0 5.2 21.5 12.2 0.0 0.0 13.3 7.2 0.0 0.0 2.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.6 10.0 4.7 9.5 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.9 0.0 0.0 0.0 1.1 0.0 0.0 15.9 11.3 11.8 0.0 9.0 0.0 0.0 0.0 2.6 0.0 8.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.0 11.9 1.0 16.6 5.8 5.6 2.0 4.8 3.4 1.1 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MARCH5 "FLJ20445, MARCH-V, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291163-92353964 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 116.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria NA NA Mitochondria "HPA056596: AB_2683181" "unprognostic (4.00e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (5.47e-3)" "unprognostic (2.33e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (9.77e-2)" "unprognostic (5.50e-3)" "unprognostic (4.02e-3)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-1)" "unprognostic (2.85e-2)" 18.2 21.7 17.5 17.7 18.3 20.7 27.1 16.8 25.7 15.5 15.4 12.7 20.7 15.8 19.3 18.8 28.0 14.8 15.4 18.4 15.8 15.1 21.7 27.6 16.5 16.6 16.3 17.9 20.9 16.7 16.3 12.3 16.3 14.8 22.2 14.8 14.5 19.4 19.3 42.6 13.7 16.0 18.1 14.0 12.1 14.4 20.1 13.5 25.0 24.5 21.5 17.3 14.7 21.0 7.3 9.4 16.8 10.2 6.5 8.7 6.6 16.2 8.8 17.5 20.0 11.9 12.4 9.0 14.6 16.1 18.2 18.7 5.9 11.7 9.5 10.1 14.2 8.0 13.4 12.1 12.2 26.2 7.1 14.3 7.6 8.3 13.8 14.5 12.1 7.6 12.7 16.5 12.0 25.2 24.3 16.0 10.2 8.3 11.9 14.5 10.3 10.7 14.0 4.1 10.6 13.3 11.6 17.9 5.6 18.6 10.5 8.1 15.0 12.6 9.4 15.4 8.7 16.4 9.5 15.5 8.6 9.4 9.3 19.9 12.1 9.2 8.4 7.8 16.9 5.7 5.2 8.3 9.0 7.6 10.2 7.6 7.3 8.4 8.0 9.4 6.7 8.7 8.3 16.8 6.5 8.5 6.2 7.8 6.6 17.5 18.3 16.8 25.7 15.8 15.1 16.3 17.9 14.8 13.5 20.8 22.1 26.1 0.0 78.5 12.2 22.9 20.4 9.4 9.1 19.2 7.9 35.2 72.9 0.0 116.8 22.5 30.7 0.0 0.0 36.8 29.4 0.0 28.8 32.6 30.8 9.5 28.6 20.3 24.8 37.2 27.3 19.9 37.1 0.0 22.9 18.6 0.0 23.0 17.3 56.2 10.9 19.4 24.5 37.4 28.3 68.3 54.6 25.5 24.7 0.0 MARCH6 "MARCH-VI, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353703-10440388 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA040841: AB_2677162, HPA063246: AB_2684970" "unprognostic (3.31e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-3)" "unprognostic (4.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.06e-2)" "unprognostic (9.52e-3)" "unprognostic (1.53e-1)" "unprognostic (1.05e-3)" "unprognostic (3.94e-2)" "unprognostic (5.58e-2)" "unprognostic (5.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "unprognostic (8.50e-3)" 22.5 25.6 28.6 21.2 25.5 57.0 62.4 42.0 53.8 21.4 23.0 24.0 18.3 28.6 24.7 24.2 22.8 25.1 22.0 35.5 27.6 23.7 31.9 28.9 35.0 33.2 29.8 39.1 34.0 41.5 56.0 27.4 20.3 33.4 21.4 18.4 20.3 28.0 23.4 49.8 23.9 32.1 27.4 38.6 31.2 26.0 25.6 26.9 18.0 26.8 17.1 20.3 24.6 36.4 13.4 7.3 15.6 12.1 9.9 15.7 9.4 12.6 19.0 31.9 24.7 18.3 14.7 26.1 20.1 18.7 17.3 22.2 18.1 33.9 13.3 30.6 18.7 24.0 17.6 16.9 13.0 23.5 28.2 15.4 17.3 63.2 12.3 12.9 20.5 19.5 17.1 14.4 17.3 19.0 17.9 16.0 14.4 20.7 30.1 15.7 14.4 11.1 15.9 11.6 10.2 13.4 17.3 13.3 19.2 13.5 24.6 13.7 19.9 37.3 20.4 13.1 15.4 17.0 11.1 15.4 21.0 20.5 10.3 14.9 21.1 30.3 19.0 15.5 14.3 14.9 15.6 8.5 13.6 13.5 9.6 15.4 13.4 13.4 13.4 7.3 11.5 15.7 14.6 13.7 9.9 12.1 5.6 11.7 9.4 28.6 25.5 42.0 53.8 27.6 23.7 29.8 39.1 33.4 26.9 50.6 44.3 66.5 0.0 124.9 104.6 89.0 53.5 62.9 56.9 68.0 62.8 47.1 18.3 0.0 9.4 58.6 66.9 93.5 0.0 24.4 54.5 0.0 48.5 71.6 32.5 128.7 95.5 58.9 54.8 10.0 64.5 39.1 89.4 0.0 73.5 52.7 0.0 56.1 72.2 52.5 79.3 77.6 80.4 84.4 67.3 119.4 68.0 58.0 58.3 0.0 MARCH7 "AXOT, MARCH-VII, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 31.6 21.1 18.3 27.4 29.0 22.6 28.9 33.1 23.0 33.4 25.3 17.0 22.0 17.1 32.3 24.1 47.6 22.7 22.4 28.1 16.9 14.4 21.8 30.9 29.5 32.9 21.6 17.8 31.6 15.4 25.3 31.5 41.3 21.5 28.8 22.3 24.8 25.7 22.6 48.0 24.2 25.2 33.8 20.4 28.9 20.0 34.1 21.8 60.4 28.5 25.5 32.9 30.0 35.1 10.0 10.1 46.1 14.5 14.0 14.6 10.5 18.4 12.7 34.2 15.3 24.9 32.9 33.1 31.0 31.3 31.9 29.3 26.2 22.2 26.2 14.1 32.2 18.1 23.3 21.0 28.6 40.9 26.8 15.5 35.6 18.4 19.8 24.2 29.1 27.8 29.2 32.7 38.9 33.8 36.4 38.2 19.2 27.0 25.4 32.2 15.1 18.6 27.9 32.3 20.3 18.2 27.7 25.3 21.7 29.3 38.5 20.4 19.1 25.3 18.6 24.8 38.8 21.6 35.4 34.4 34.2 20.6 20.9 17.5 20.2 21.3 35.8 21.2 17.6 31.8 24.8 10.3 20.6 11.1 10.6 13.3 10.0 12.1 12.6 10.1 9.7 14.6 14.1 46.1 14.0 14.5 7.9 12.5 10.5 18.3 29.0 33.1 23.0 16.9 14.4 21.6 17.8 21.5 21.8 68.5 35.6 53.7 0.0 76.4 37.4 78.7 10.2 57.6 44.3 34.9 25.5 31.0 16.6 0.0 208.1 38.3 17.5 23.3 0.0 29.9 37.4 0.0 53.3 28.0 29.4 46.1 27.6 52.2 38.4 46.0 45.8 42.0 21.9 0.0 24.9 38.9 0.0 17.5 38.5 32.1 34.2 58.2 45.3 77.0 31.7 79.3 37.0 41.5 21.9 0.0 MARCH8 "c-MIR, CMIR, MARCH-VIII, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 20 "Cone photoreceptor cells: 106.0;Early spermatids: 508.4;Late spermatids: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved NA NA "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favorable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favorable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 10.0 17.6 13.5 11.4 16.0 28.8 12.1 37.5 12.2 10.3 14.6 24.5 8.5 9.7 14.3 8.2 7.5 11.1 9.9 14.1 12.7 11.8 11.0 16.7 10.3 13.5 19.0 9.3 14.2 18.2 15.1 18.1 13.2 14.5 8.8 12.9 12.9 11.5 11.4 9.0 8.9 18.8 12.4 18.2 14.3 9.7 43.2 14.9 10.5 11.5 8.5 13.6 11.0 8.0 5.3 1.7 13.6 1.8 7.3 4.7 2.4 9.3 9.4 8.0 7.1 11.7 14.6 6.0 4.3 20.1 7.9 8.7 2.4 9.7 13.4 7.4 12.4 7.2 1.7 8.7 7.3 7.4 20.3 9.6 5.2 4.3 5.6 8.1 6.2 23.0 11.9 9.5 4.0 10.7 7.9 12.9 12.9 14.5 13.2 6.1 3.3 6.3 4.0 2.6 1.3 3.0 7.1 8.0 3.9 6.0 5.4 7.1 9.9 8.4 2.0 8.0 8.2 12.4 2.9 8.8 6.3 8.1 9.1 6.7 23.3 18.6 5.9 12.3 8.7 1.6 9.7 1.1 10.0 3.1 1.8 4.7 3.5 3.4 3.3 1.6 5.3 2.7 3.3 13.6 7.3 0.9 1.7 3.1 2.4 13.5 16.0 37.5 12.2 12.7 11.8 19.0 9.3 14.5 14.9 8.9 7.5 13.4 0.0 3.1 6.6 21.0 10.2 6.7 12.5 10.4 106.0 1.7 5.0 0.0 508.4 8.7 20.2 70.0 0.0 1.1 5.6 0.0 17.3 22.5 5.4 11.1 39.0 12.9 15.9 175.4 7.8 7.0 5.0 0.0 11.9 6.3 0.0 10.4 8.5 9.9 23.0 6.5 2.8 21.5 13.4 3.3 1.4 8.3 11.2 0.0 MARCH9 "FLJ36578, RNF179" ENSG00000139266 "Membrane associated ring-CH-type finger 9" Q86YJ5 12 57755098-57760407 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.9;Cone photoreceptor cells: 119.8;Horizontal cells: 54.0;Muller glia cells: 63.3;Rod photoreceptor cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 12 "RH-30: 110.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.96e-2)" "unprognostic (6.78e-2)" "unprognostic (1.90e-3)" "prognostic favorable (3.07e-4)" "unprognostic (2.16e-1)" "unprognostic (6.85e-2)" "unprognostic (8.15e-3)" "prognostic favorable (1.54e-5)" "unprognostic (7.76e-2)" "prognostic favorable (1.59e-4)" "unprognostic (1.08e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.98e-5)" "unprognostic (2.44e-1)" "unprognostic (2.86e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" 5.9 11.8 11.0 10.7 14.1 6.1 8.8 25.0 16.6 9.5 9.3 7.8 17.5 10.1 6.8 11.9 8.3 9.6 14.3 12.2 10.8 9.9 16.9 5.6 16.5 16.6 7.7 11.0 6.4 14.4 26.3 24.6 10.3 7.4 11.0 9.0 16.8 12.3 17.6 10.5 13.4 12.7 7.0 6.1 19.4 11.6 5.2 6.8 37.6 20.2 6.2 17.8 9.2 7.7 6.8 11.0 2.2 0.7 3.0 6.1 1.3 3.1 1.5 2.4 2.6 0.2 0.0 3.2 0.4 3.3 1.9 1.8 2.0 2.5 7.6 2.6 0.0 3.2 2.8 4.0 3.4 1.2 4.5 4.4 1.0 1.1 1.0 2.3 0.9 1.6 0.4 3.5 0.5 1.9 5.6 0.8 7.7 1.4 7.9 0.5 2.9 4.8 1.1 1.6 2.2 3.4 4.0 110.2 8.2 3.7 2.7 5.6 3.6 0.2 0.2 2.0 1.2 5.6 1.8 0.0 2.4 2.0 1.3 1.5 8.9 4.0 4.7 2.7 0.2 2.4 2.2 0.5 0.1 4.0 0.7 5.9 5.3 6.0 5.2 1.5 6.8 6.1 4.6 0.2 3.0 0.2 11.0 3.6 1.3 11.0 14.1 25.0 16.6 10.8 9.9 7.7 11.0 7.4 6.8 20.8 12.3 17.1 0.0 9.2 72.9 9.4 12.7 1.4 5.7 8.7 119.8 1.6 5.0 0.0 0.3 7.3 5.3 0.0 0.0 0.7 3.1 0.0 2.3 3.9 6.6 54.0 14.6 12.3 1.2 0.8 9.2 3.3 6.8 0.0 8.0 63.3 0.0 2.9 10.6 7.0 188.1 6.5 4.7 2.3 3.4 8.3 0.9 10.1 11.0 0.0 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528183-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 23.6;Cardiomyocytes: 19.9;Cone photoreceptor cells: 29.5;Spermatocytes: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 35.7;SuSa: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favorable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 14.3 5.6 11.4 4.6 13.5 0.9 9.0 15.2 22.7 9.8 6.7 4.7 6.4 2.1 7.8 26.6 9.4 5.9 5.0 19.1 10.0 12.5 4.7 1.5 4.8 2.3 10.3 12.4 3.7 3.0 5.8 12.1 3.9 13.2 7.2 4.1 6.2 5.0 11.3 4.2 3.5 3.4 10.1 7.1 3.2 4.3 16.0 4.6 0.4 8.4 5.3 5.7 8.8 14.9 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 4.5 1.2 0.0 0.0 1.9 1.5 2.2 1.6 2.4 0.0 0.0 0.0 0.0 0.0 3.3 2.3 9.5 6.2 1.1 0.0 7.0 0.0 2.4 0.0 0.0 0.7 0.9 0.7 5.3 0.0 2.9 0.8 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 8.8 4.5 2.2 0.0 7.1 0.0 0.0 35.7 6.6 5.8 0.3 0.3 0.4 11.1 0.7 0.0 0.0 0.0 3.5 4.8 6.2 0.0 0.0 0.0 1.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 13.5 15.2 17.5 10.0 12.5 10.3 12.4 13.2 4.6 0.0 0.3 0.5 2.4 3.1 23.6 19.9 0.0 1.4 2.3 3.5 29.5 1.7 0.0 1.6 5.5 3.0 1.1 0.0 0.0 1.8 3.1 1.7 0.0 0.0 0.2 9.5 8.6 4.3 0.3 3.0 2.0 0.0 0.0 0.0 0.2 15.1 0.1 0.0 6.0 0.0 10.6 0.0 15.1 17.9 5.2 2.9 0.8 0.0 0.4 3.9 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911019 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 9.7 11.6 16.5 16.3 21.4 18.5 13.8 24.7 26.1 15.2 20.5 20.0 11.1 21.3 13.6 7.5 48.4 13.6 14.4 14.7 17.0 10.1 11.9 12.4 15.4 16.3 18.1 13.7 11.0 17.3 21.8 22.4 21.1 15.0 14.9 19.8 10.6 20.7 14.3 15.7 35.8 26.9 13.3 13.3 21.6 16.8 9.8 18.7 22.9 15.9 13.6 23.5 14.8 21.3 2.9 1.9 9.8 1.9 3.3 4.5 1.2 22.7 15.2 12.5 13.1 6.9 9.0 17.3 9.3 8.9 13.4 10.4 16.3 24.1 16.8 16.4 9.7 14.5 29.5 12.0 14.5 11.6 11.6 9.4 18.5 12.0 10.6 7.7 20.1 24.5 4.9 19.8 12.3 10.7 6.3 11.0 15.9 15.7 19.4 8.8 28.0 21.0 14.3 14.2 18.4 11.1 17.4 9.3 18.6 10.0 18.8 17.2 11.6 16.0 41.1 10.7 14.0 29.9 12.0 10.4 14.2 8.9 18.3 10.3 11.8 12.2 16.5 9.7 10.6 11.3 2.7 1.7 4.4 2.9 1.5 4.5 2.3 3.2 3.1 1.9 2.9 2.6 2.4 9.8 3.3 1.9 1.7 1.5 1.2 16.5 21.4 24.7 26.1 17.0 10.1 18.1 13.7 15.0 18.7 6.0 5.0 13.9 16.2 22.3 26.0 10.9 35.7 6.7 6.8 19.2 7.9 19.2 1.7 18.5 0.4 11.9 59.3 0.0 18.5 16.8 10.6 28.8 17.3 12.1 15.7 19.1 28.7 13.5 19.5 0.7 11.8 11.3 3.3 8.2 35.1 19.1 20.0 35.9 10.3 6.9 17.8 19.4 9.2 8.4 21.8 30.1 54.3 23.6 28.2 30.9 MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385392-103503831 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "eosinophil: 42.2" "Lineage enriched" "Detected in many" 23 "granulocytes: 42.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved NA NA "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" 20.8 31.9 24.6 20.9 29.5 62.7 19.7 59.1 30.2 25.3 20.8 33.2 19.9 17.4 28.5 28.4 24.4 23.1 22.2 33.6 24.9 22.4 20.3 20.1 25.9 20.8 29.6 23.3 24.6 30.7 28.1 30.9 20.5 27.4 19.3 20.0 23.6 18.3 23.1 40.9 19.9 19.2 26.8 20.9 26.8 26.9 24.1 30.3 29.1 25.8 23.1 23.0 20.8 29.0 1.2 1.2 42.2 1.1 0.8 1.8 0.4 13.4 16.3 23.7 17.9 28.5 22.3 20.5 23.8 25.2 28.9 27.8 12.8 21.1 16.0 15.1 22.4 12.5 25.3 25.9 25.7 36.9 18.6 11.5 20.7 17.3 16.0 53.8 23.5 13.8 25.9 23.8 23.4 47.9 26.4 26.7 16.0 21.2 37.4 21.6 36.0 16.1 20.9 17.4 22.7 24.6 21.1 24.3 12.8 25.5 28.6 20.9 20.9 25.3 17.4 23.2 28.1 23.6 20.2 23.0 15.5 11.1 28.9 21.2 24.2 30.7 19.2 18.9 19.0 20.9 0.4 1.1 42.2 1.1 0.8 0.9 1.2 1.6 1.8 1.1 0.9 1.8 1.4 3.1 0.8 0.7 1.2 1.6 0.4 24.6 29.5 59.1 30.2 24.9 22.4 29.6 23.3 27.4 30.3 53.6 64.4 40.2 43.5 39.3 70.1 69.8 35.7 25.4 52.4 36.6 153.2 26.8 10.0 40.4 26.7 50.1 30.4 186.9 36.6 26.3 42.6 53.5 47.3 26.8 26.4 55.6 30.0 47.3 26.0 38.0 56.4 44.1 35.4 50.5 28.7 36.1 46.0 29.2 55.5 15.8 90.5 32.3 43.7 40.2 55.6 45.7 41.1 42.6 28.4 99.3 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol NA NA Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 11.8 13.0 19.4 10.3 26.0 8.4 15.2 21.9 28.6 11.4 10.2 9.0 12.9 6.6 14.0 17.5 13.5 12.9 13.4 14.7 22.2 15.7 8.7 13.5 11.7 10.5 14.3 21.6 21.0 16.8 13.7 12.9 12.1 15.0 12.2 6.3 14.1 12.1 14.2 40.7 20.6 7.5 14.1 10.8 12.4 10.3 32.1 12.3 11.2 10.5 11.5 9.4 13.7 17.9 1.0 2.8 3.5 2.9 1.8 4.3 1.2 8.9 3.8 15.1 11.0 10.8 17.2 4.2 6.6 10.4 9.9 9.3 2.3 5.1 4.3 5.7 12.1 8.2 6.1 10.7 9.7 5.6 7.9 8.8 8.6 4.7 8.2 19.9 2.1 7.5 21.4 13.8 8.3 9.6 17.5 13.2 9.6 10.9 10.8 10.7 7.5 7.6 6.7 6.5 7.4 3.3 29.6 4.9 2.8 9.3 7.2 28.4 12.5 9.8 8.7 5.1 15.3 4.1 12.5 10.7 8.9 6.8 6.0 4.3 12.1 9.6 4.9 9.5 4.0 7.1 3.5 2.9 0.7 3.4 2.2 0.7 0.9 1.2 4.3 0.8 1.0 2.3 2.6 2.9 1.8 2.0 2.8 2.4 1.2 19.4 26.0 21.9 22.7 22.2 15.7 14.3 21.6 15.0 12.3 11.9 1.9 3.0 9.5 22.1 20.9 7.3 10.2 0.0 2.3 8.7 23.6 3.3 10.0 7.8 2.1 10.5 3.3 0.0 5.3 1.1 7.5 8.5 2.3 10.9 5.8 112.8 5.8 18.4 8.4 4.1 15.0 6.1 3.3 2.8 6.0 13.2 7.3 3.2 13.1 5.6 14.6 0.0 7.3 0.5 6.1 21.1 9.6 6.9 3.4 14.0 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874951 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 22.6;Cone photoreceptor cells: 41.2;Early spermatids: 13.0;Horizontal cells: 14.3;Rod photoreceptor cells: 18.7" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "MAIT T-cell: 3.6;T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "AN3-CA: 15.0;SCLC-21H: 26.5;SH-SY5Y: 13.2;U-266/70: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 1.2 5.2 20.4 1.7 13.6 1.6 1.5 51.0 40.1 1.1 1.5 1.4 0.0 1.7 1.3 1.2 1.3 1.2 1.6 1.3 16.1 16.3 1.2 1.3 1.2 1.3 8.8 19.5 1.5 1.6 1.2 10.4 1.2 19.9 1.2 1.3 1.6 1.3 1.2 1.2 4.1 1.6 1.3 4.2 1.2 1.5 3.9 2.7 0.0 1.2 0.0 1.3 1.2 0.2 0.4 0.0 0.0 0.2 0.0 3.6 0.1 2.2 1.0 1.0 15.0 0.0 0.0 1.2 0.1 0.1 0.2 0.6 0.5 0.9 3.6 1.7 0.0 2.5 0.0 4.4 0.0 0.0 2.5 2.9 0.3 3.6 1.6 0.0 0.8 0.8 0.3 0.0 0.5 0.5 0.8 0.0 9.8 3.1 1.9 0.0 0.5 1.5 0.4 4.5 0.4 4.6 9.9 3.0 5.1 0.2 0.1 26.5 13.2 0.5 0.9 2.7 0.8 2.4 1.3 0.0 1.8 2.8 2.0 0.5 10.8 8.6 2.1 3.3 2.0 0.1 0.0 0.2 0.0 0.0 0.2 3.6 0.1 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 2.0 0.1 20.4 13.6 51.0 34.3 16.1 16.3 8.8 19.5 19.9 2.7 0.0 3.7 0.0 1.9 0.8 22.6 0.8 0.0 1.4 0.0 0.0 41.2 0.4 0.0 0.1 13.0 1.0 0.7 0.0 0.4 0.4 0.7 0.9 1.1 0.8 0.2 14.3 0.0 0.6 1.2 6.5 0.6 1.0 5.0 0.0 0.0 3.6 0.3 2.9 1.1 0.1 18.7 0.0 0.8 2.8 4.1 1.3 0.2 1.0 0.4 0.6 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036124 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.3" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 43.3;Cone photoreceptor cells: 51.1;Enterocytes: 45.1;Late spermatids: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 8.9 4.3 7.0 9.9 8.1 3.7 7.1 7.1 11.8 13.6 15.2 8.4 6.6 11.2 16.7 7.7 8.8 9.5 9.9 25.5 5.0 7.6 4.8 6.1 5.9 4.4 8.9 7.3 19.8 3.6 9.1 10.5 5.5 10.1 13.9 13.9 7.2 8.3 8.6 83.3 5.5 21.3 14.9 5.8 2.5 9.0 24.8 4.8 3.5 5.7 27.4 7.5 16.3 10.6 0.5 1.9 1.4 4.3 1.4 1.4 0.5 14.9 12.1 12.3 9.4 16.1 23.1 13.6 16.0 11.6 14.8 16.5 13.9 4.9 23.4 7.5 19.5 30.0 7.4 14.8 9.1 15.7 11.2 8.0 10.6 13.7 12.7 14.0 5.6 13.6 17.7 11.8 24.8 19.8 18.6 13.8 6.1 8.1 7.2 17.6 10.2 8.2 5.8 10.1 10.1 13.9 12.2 20.6 4.4 7.7 8.1 17.1 10.1 18.8 24.6 8.0 14.1 11.2 5.6 13.4 28.7 18.5 14.9 15.8 9.7 8.7 8.5 19.1 7.7 11.8 0.0 1.1 1.4 1.4 0.6 1.4 0.2 0.7 1.4 1.9 0.5 0.5 1.0 0.0 1.4 4.3 0.1 0.0 0.5 7.0 8.1 7.1 11.8 5.0 7.6 8.9 7.3 10.1 4.8 0.0 1.3 0.0 4.2 3.8 14.9 43.3 2.5 1.4 7.9 3.5 51.1 4.4 1.7 4.2 27.6 5.3 45.1 0.0 5.4 4.0 6.6 7.8 0.0 5.6 5.5 4.8 11.6 3.1 1.6 44.9 8.3 6.4 6.8 1.0 18.3 3.0 6.7 26.6 9.6 4.2 12.7 6.5 6.1 28.4 11.7 2.4 4.6 1.9 18.1 6.0 MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097793-18151692 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.5" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 21.5;Late spermatids: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favorable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favorable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" 4.6 3.5 20.7 8.3 36.1 12.3 1.8 1.1 72.5 3.8 5.3 19.0 0.2 9.1 3.6 4.9 2.2 4.9 3.1 2.1 19.7 9.3 3.6 6.4 4.6 9.9 13.0 33.6 4.6 14.3 7.1 7.7 2.6 13.0 2.7 4.4 0.7 4.6 4.2 2.6 6.9 8.8 3.0 7.9 11.4 3.9 2.1 12.5 1.8 2.4 0.3 9.4 3.3 2.4 4.4 10.3 23.2 9.7 5.8 8.4 3.1 3.3 5.0 2.3 10.1 6.8 5.5 5.5 3.4 2.2 2.4 3.5 5.0 4.7 8.7 5.2 3.4 2.6 1.8 3.3 1.9 1.7 7.4 4.1 4.0 5.2 7.9 5.8 2.1 13.3 6.3 5.7 3.6 1.4 3.3 1.1 6.0 4.0 5.7 2.7 6.0 4.4 7.0 2.4 7.4 6.2 12.1 2.0 6.4 1.8 1.5 3.8 6.2 4.8 2.8 2.0 1.7 3.2 4.9 4.0 3.1 3.3 13.0 1.4 6.2 8.4 8.0 6.8 11.2 2.8 0.1 4.5 9.4 8.4 5.6 6.2 4.1 4.7 3.3 2.1 4.4 3.7 6.4 23.2 5.8 9.7 10.3 5.0 3.1 20.7 36.1 1.1 72.5 19.7 9.3 13.0 33.6 13.0 12.5 6.0 10.3 7.8 0.7 0.5 3.2 1.1 7.6 0.0 3.4 8.7 2.0 0.5 3.3 2.8 9.1 1.6 20.0 0.0 9.2 1.2 2.2 0.8 2.3 12.5 6.9 0.0 2.4 7.4 21.5 24.6 3.7 7.9 5.0 6.4 6.9 0.8 6.1 8.6 6.3 8.7 0.6 0.0 1.8 0.6 2.8 1.9 0.3 9.6 8.6 0.6 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Basal glandular cells: 428.6;Basal keratinocytes: 327.4;Glandular cells: 324.3;Suprabasal keratinocytes: 348.9;Urothelial cells: 641.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 17.8;HDLM-2: 22.6;HEL: 18.7;RT4: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 16.2 12.9 10.2 6.9 11.8 2.5 12.6 6.2 19.4 13.9 6.9 6.3 6.3 6.3 14.4 8.9 31.2 11.6 9.7 24.5 9.9 8.1 14.2 9.5 13.1 5.0 6.5 9.2 20.2 5.9 35.6 16.7 18.4 11.1 10.1 5.3 5.7 13.7 8.7 12.7 16.9 6.8 11.4 5.6 6.0 8.2 10.7 5.0 37.5 8.1 21.8 20.6 13.6 22.3 3.4 1.1 12.1 0.9 2.4 7.5 1.4 7.6 4.2 2.1 0.1 6.9 6.2 5.0 1.7 2.6 0.6 0.5 3.8 2.1 0.5 3.6 1.4 1.6 6.9 6.4 17.8 0.7 22.6 2.1 18.7 2.4 1.6 0.5 0.0 6.6 10.3 9.8 3.9 7.9 7.3 14.1 1.7 1.8 2.1 4.8 6.6 2.7 0.1 1.4 0.6 3.4 0.6 1.8 0.4 1.7 22.9 3.0 2.4 2.3 0.9 0.1 1.5 1.5 0.1 13.5 1.6 2.3 2.5 2.9 5.5 2.4 0.1 4.3 0.0 1.3 12.1 0.4 0.8 1.2 0.5 2.9 3.4 4.7 1.2 0.4 2.1 5.0 2.1 4.1 2.4 0.9 1.1 7.5 1.4 10.2 11.8 6.2 19.4 9.9 8.1 6.5 9.2 11.1 5.0 29.8 44.7 9.0 428.6 327.4 18.2 114.6 17.8 29.4 59.1 17.4 2.0 33.2 31.5 46.4 104.5 72.0 17.3 0.0 103.5 42.2 34.0 324.3 92.3 37.2 4.6 7.9 30.9 60.2 6.0 92.7 38.3 9.8 45.5 2.8 14.9 56.5 55.6 15.6 30.8 73.9 3.5 38.8 35.8 11.4 8.5 348.9 114.8 15.2 15.0 641.7 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27186924 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 9.1 7.0 3.6 8.9 6.1 21.1 8.3 4.0 7.5 7.4 7.6 3.8 5.7 5.7 6.0 6.7 12.3 5.4 5.3 5.6 6.8 4.5 6.5 7.1 10.2 14.8 5.4 5.7 7.0 12.7 6.7 6.3 14.2 6.7 5.5 7.1 5.6 8.0 4.7 4.0 10.1 10.0 6.1 5.6 8.7 6.2 11.3 2.3 21.1 6.5 4.3 12.3 8.7 7.5 3.9 2.6 5.6 4.9 2.3 4.0 1.8 11.9 9.6 18.4 6.8 2.8 4.2 10.9 17.9 7.5 29.7 36.6 11.6 12.0 9.6 6.8 7.5 14.4 11.6 11.7 7.1 21.1 8.1 11.3 11.3 6.7 6.7 1.6 4.3 8.5 2.5 3.2 17.9 3.5 3.9 6.4 7.8 8.6 21.6 18.0 7.9 14.0 4.7 13.7 6.7 3.9 9.0 30.7 7.9 7.3 4.5 8.2 11.8 11.3 7.6 7.9 12.7 7.6 9.1 5.5 7.4 15.6 18.9 15.7 2.6 4.2 14.1 8.1 13.1 6.1 0.1 4.4 3.8 2.0 4.3 3.0 2.6 2.5 1.8 2.5 3.9 2.5 2.3 5.6 2.3 4.9 2.6 4.0 1.8 3.6 6.1 4.0 7.5 6.8 4.5 5.4 5.7 6.7 2.3 6.0 8.5 7.2 4.0 9.7 1.9 1.6 0.0 4.0 9.1 1.8 0.0 3.3 0.0 3.2 1.7 3.6 3.0 0.0 2.2 20.7 5.8 3.3 12.7 1.7 5.1 3.2 4.1 2.5 12.0 1.5 2.8 5.6 0.0 1.8 3.4 1.5 3.6 1.9 2.5 1.4 0.9 0.0 5.9 11.2 16.4 8.7 5.1 8.7 3.5 5.9 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808176-68850686 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 95.6;U-698: 91.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB000086: AB_563872, CAB016303: AB_627920" "unprognostic (1.16e-1)" "prognostic favorable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favorable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 16.6 15.3 11.1 12.5 10.8 23.1 12.5 12.0 11.3 13.1 16.6 13.6 11.9 5.2 8.8 9.4 14.2 12.6 12.3 9.0 8.8 8.6 11.2 25.7 15.9 13.3 14.2 7.1 11.0 21.4 11.4 10.4 24.5 11.9 12.6 21.5 7.8 10.5 11.1 19.5 9.8 7.2 10.8 10.8 15.3 9.8 6.5 11.5 29.5 13.6 10.8 14.1 13.5 12.6 4.9 4.0 19.3 6.4 3.6 4.4 3.0 3.1 7.5 7.9 3.9 10.2 9.5 40.2 8.9 8.9 4.7 7.6 4.5 1.4 33.3 2.5 5.8 1.3 1.9 5.4 95.6 7.6 8.8 3.7 6.1 6.3 20.2 10.0 5.4 5.6 14.6 8.2 18.7 12.8 4.7 13.2 5.8 6.2 8.1 9.0 5.1 7.1 1.8 6.6 1.6 1.4 25.3 5.4 2.7 2.9 26.6 6.0 3.5 5.6 4.4 1.9 16.7 10.4 3.6 14.1 3.6 6.8 2.9 3.1 12.3 7.8 91.9 5.5 2.1 14.7 5.3 5.4 4.8 4.4 4.0 3.9 4.7 3.7 4.1 2.8 4.9 4.0 3.7 19.3 3.6 6.4 4.0 3.8 3.0 11.1 10.8 12.0 11.3 8.8 8.6 14.2 7.1 11.9 11.5 29.8 48.8 22.9 24.5 13.9 27.9 17.8 25.5 97.7 62.6 24.4 31.4 43.9 11.6 18.1 1.1 20.2 16.6 0.0 20.8 23.6 22.4 34.7 31.3 38.4 16.5 28.6 24.1 22.1 44.9 1.8 17.8 21.8 11.8 31.5 23.5 26.4 19.8 20.1 14.2 15.3 34.5 19.4 21.7 13.9 20.6 19.3 78.8 25.4 19.7 74.5 MED1 "CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2" ENSG00000125686 "Mediator complex subunit 1" Q15648 17 39404285-39451286 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017696, HPA052818" Approved Supported Nucleoplasm NA NA 170000 Nucleoplasm "CAB017696: AB_1128703, HPA052818: AB_2681962" "unprognostic (1.77e-1)" "unprognostic (1.63e-1)" "unprognostic (9.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.50e-1)" "unprognostic (7.86e-2)" "unprognostic (1.95e-3)" "unprognostic (4.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (2.00e-1)" "unprognostic (5.94e-2)" "unprognostic (9.40e-2)" "unprognostic (5.79e-2)" 16.4 13.8 11.8 14.8 13.7 15.5 15.1 19.8 16.5 16.9 14.6 18.8 9.3 10.3 17.9 9.7 15.0 14.3 10.9 12.8 11.6 10.5 13.0 13.3 12.3 17.7 12.0 10.3 22.2 16.2 34.5 21.1 16.5 14.5 12.5 14.2 16.5 13.4 11.6 19.5 16.1 14.1 17.1 14.0 20.4 13.0 15.1 12.1 34.1 13.2 12.1 22.5 16.6 13.4 6.6 4.9 4.4 4.0 5.0 6.1 2.7 8.1 11.0 13.8 9.4 10.1 10.3 11.1 10.0 10.9 13.8 13.5 10.5 8.1 22.0 11.4 12.4 15.8 16.2 16.5 9.9 21.9 21.2 13.8 13.8 10.4 10.5 10.9 24.6 14.6 9.7 10.1 16.9 24.7 8.5 11.7 12.6 17.7 11.9 11.2 4.6 22.9 9.3 8.9 7.9 6.5 17.2 18.6 9.4 8.1 9.5 8.8 10.0 13.2 87.5 11.5 12.3 16.2 14.1 10.4 10.7 13.4 11.9 17.6 10.9 14.6 22.7 10.6 12.1 13.1 3.2 4.0 4.4 5.2 3.9 5.8 6.6 5.5 5.8 4.0 6.4 5.4 6.1 3.3 5.0 2.6 4.9 3.3 2.7 11.8 13.7 19.8 16.5 11.6 10.5 12.0 10.3 14.5 12.1 23.8 11.5 11.9 11.5 24.2 13.6 16.9 10.2 17.4 26.1 8.7 13.7 14.5 3.3 10.8 5.0 19.6 9.5 0.0 10.3 10.6 16.0 13.2 9.2 17.0 12.9 11.1 13.2 17.8 21.9 6.6 13.6 14.7 20.3 10.0 14.1 12.3 11.8 10.5 17.0 7.2 10.5 19.4 13.7 18.4 18.1 28.5 18.5 20.0 16.0 14.0 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.4" "Cell type enhanced" "Detected in many" 15 "Extravillous trophoblasts: 36.8;Spermatocytes: 10.2;Spermatogonia: 19.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA017214 Uncertain NA Yes "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 1.5 1.1 0.3 11.4 0.6 7.7 2.6 0.2 0.8 2.1 5.9 0.3 0.1 4.5 1.2 1.5 12.2 0.4 1.6 1.3 0.5 0.4 1.2 1.3 2.0 8.3 0.4 0.1 0.7 0.8 0.0 0.3 6.3 0.5 0.7 7.8 0.4 2.3 0.1 0.9 2.8 4.6 1.9 1.0 5.2 2.9 11.3 0.4 42.4 0.5 7.2 12.6 1.5 3.3 0.1 0.6 1.0 0.1 0.4 4.8 0.5 35.6 18.4 24.8 14.6 3.4 5.9 14.4 26.5 18.7 37.2 45.9 14.0 14.1 11.9 8.5 13.0 32.5 12.3 21.6 16.6 41.1 32.5 8.6 9.4 21.8 14.0 1.3 14.5 11.9 2.1 3.0 28.6 16.3 4.8 18.7 18.6 11.9 19.1 30.4 11.9 18.0 6.8 19.8 16.1 14.4 16.7 16.7 7.6 11.4 12.0 16.8 12.5 14.1 13.6 8.6 14.4 11.4 6.9 9.2 20.1 25.4 16.9 24.1 3.8 13.6 17.9 12.7 10.8 27.2 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 4.8 0.5 0.3 0.6 0.2 0.8 0.5 0.4 0.4 0.1 0.5 0.4 0.0 0.0 0.0 0.4 4.0 0.0 0.3 0.0 1.4 2.3 0.0 0.0 4.2 0.0 0.8 1.8 0.0 1.2 0.0 1.0 36.8 2.1 0.2 0.0 0.2 8.4 0.0 0.0 1.3 0.6 1.8 1.1 2.3 0.0 5.4 1.3 0.0 1.1 2.9 0.0 0.0 0.0 0.0 0.9 10.2 19.0 1.5 7.4 0.0 3.7 1.4 METTL1 "C12orf1, TRM8, TRMT8" ENSG00000037897 "Methyltransferase like 1" Q9UBP6 12 57768471-57772793 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 53.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 6 "RH-30: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020914, HPA050450" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA020914: AB_1853830, HPA050450: AB_2681130" "unprognostic (5.24e-2)" "unprognostic (2.60e-1)" "unprognostic (9.43e-2)" "unprognostic (3.46e-1)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (4.25e-6)" "unprognostic (5.67e-2)" "unprognostic (6.19e-2)" "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.55e-6)" "unprognostic (7.75e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" 12.2 16.6 6.7 13.8 8.8 8.4 12.3 2.2 6.9 7.6 7.6 4.5 10.8 3.3 9.4 21.2 10.3 9.0 10.7 8.1 5.8 5.0 20.9 15.3 7.7 8.8 7.4 4.6 17.6 34.9 10.9 10.6 8.3 6.5 11.0 10.3 5.3 17.9 17.2 20.4 8.5 5.7 10.5 5.0 8.2 7.3 11.4 5.4 4.5 15.1 15.6 9.8 8.8 7.8 6.1 12.6 0.7 6.7 7.3 18.6 5.1 6.1 11.2 4.7 4.3 6.4 4.4 6.4 6.6 6.0 11.1 6.0 7.8 8.6 7.4 12.3 8.0 6.3 7.3 7.2 10.2 10.8 4.4 8.4 8.6 4.3 9.5 4.5 9.3 4.5 3.9 9.3 12.4 8.7 5.4 5.9 4.8 7.9 7.4 5.6 11.9 6.5 11.1 11.1 8.2 11.3 5.8 78.7 10.9 9.7 7.7 5.0 4.5 6.9 7.6 6.1 4.9 10.0 8.8 4.4 4.5 5.0 7.9 8.7 3.4 2.5 9.0 6.4 6.7 9.3 0.0 4.7 0.0 5.3 6.7 18.6 4.7 6.9 6.5 10.3 6.1 9.5 9.2 0.7 7.3 1.1 12.6 3.3 5.1 6.7 8.8 2.2 6.9 5.8 5.0 7.4 4.6 6.5 5.4 8.9 3.5 8.9 11.4 9.3 2.9 3.6 2.5 1.4 17.0 5.2 0.0 15.0 21.6 15.2 11.3 7.1 1.3 0.0 20.6 19.6 12.0 7.7 12.7 9.0 22.2 3.2 6.3 4.3 1.0 8.6 10.3 9.0 6.8 27.1 5.6 1.6 12.8 0.0 4.6 53.6 5.5 0.0 14.7 4.8 14.7 9.2 8.1 4.3 9.1 10.5 METTL3 "M6A, MT-A70, Spo8" ENSG00000165819 "Methyltransferase like 3" Q86U44 14 21498133-21511375 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, Immunity, Innate immunity, Spermatogenesis" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 132.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.19e-5)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "prognostic favorable (2.78e-4)" "prognostic favorable (2.72e-4)" "unprognostic (4.52e-2)" "unprognostic (4.64e-3)" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (5.36e-2)" "unprognostic (1.22e-1)" 13.1 21.0 15.7 18.3 20.4 6.8 17.4 27.1 16.4 13.5 12.8 16.3 20.4 7.7 17.1 19.8 14.3 20.9 11.2 17.3 16.3 8.6 14.6 14.0 14.2 18.4 21.7 15.2 18.2 14.2 25.8 21.3 16.0 16.3 19.3 13.9 12.2 17.0 19.3 18.8 17.0 11.9 17.6 13.8 17.5 12.9 21.6 20.6 15.4 19.2 13.3 21.8 15.1 14.8 13.0 12.6 7.7 10.3 15.3 14.3 8.1 16.6 24.9 23.7 9.5 18.4 15.2 11.9 15.3 11.3 18.4 21.6 9.4 19.7 17.4 9.9 9.5 24.1 17.7 29.0 15.1 29.2 16.4 17.1 10.8 13.8 37.2 7.5 14.5 12.3 11.4 13.3 11.4 13.4 8.1 24.0 9.0 13.2 10.0 24.3 12.2 12.9 11.6 20.2 28.2 30.8 12.9 18.8 15.4 16.8 11.2 14.7 15.9 16.7 22.0 15.6 19.7 17.4 9.6 15.6 6.5 11.0 12.0 10.4 10.6 13.2 12.1 8.0 11.7 13.8 5.1 8.1 7.7 8.7 10.3 12.7 13.0 10.5 9.6 10.5 10.3 11.0 9.7 0.9 15.3 8.4 12.6 14.3 8.1 15.7 20.4 27.1 16.4 16.3 8.6 21.7 15.2 16.3 20.6 11.9 15.3 14.3 20.7 13.3 23.6 30.5 12.7 16.0 12.5 12.2 13.7 26.1 3.3 12.6 132.7 11.7 4.2 23.3 8.6 12.2 16.4 16.1 8.1 9.5 14.4 20.6 10.4 10.4 7.1 15.9 15.8 12.9 15.1 19.8 7.6 16.2 9.0 3.5 18.7 7.2 18.7 32.3 14.2 32.6 17.9 10.8 21.2 13.8 11.1 17.6 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 155.5" "Cell type enhanced" "Detected in some" 24 "Early spermatids: 50.7;Late spermatids: 90.5;Proximal tubular cells: 18.9" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "neutrophil: 14.1" "Lineage enriched" "Detected in single" 104 "granulocytes: 14.1" "Cell line enhanced" "Detected in some" "A549: 3.7;BJ hTERT+: 3.3;HL-60: 5.5;U-937: 8.7;WM-115: 2.1" "Region enriched" "Detected in single" 12 "olfactory region: 3.1" HPA002270 Enhanced NA NA 68000 "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 0.9 0.2 0.3 0.8 0.2 6.9 0.3 0.2 0.2 0.2 59.4 0.1 7.6 25.2 0.2 36.0 0.2 1.0 0.1 0.3 0.2 0.2 8.7 0.4 2.1 0.1 0.3 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.0 0.1 0.2 3.2 0.2 0.1 155.5 0.1 0.3 8.3 0.7 4.3 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 3.7 0.2 0.1 0.0 0.0 0.5 0.1 3.3 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.4 0.1 0.3 0.0 0.1 0.0 8.7 2.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.1 0.0 4.5 0.0 0.0 0.0 0.0 1.1 0.0 2.7 2.3 12.2 0.0 0.0 1.7 0.0 50.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 90.5 0.6 1.8 0.0 0.0 0.4 0.5 0.2 0.0 0.4 18.9 0.0 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.2 0.2 MGEA5 "MEA5, NCOAT, OGA" ENSG00000198408 "Meningioma expressed antigen 5 (hyaluronidase)" O60502 10 101784443-101818465 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol NA NA Cytosol "HPA036141: AB_10672079, HPA076501: AB_2686802" "unprognostic (4.34e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (4.63e-1)" "unprognostic (2.06e-1)" "unprognostic (2.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-3)" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.90e-1)" "unprognostic (9.23e-3)" 29.5 17.5 51.9 27.4 54.4 49.3 35.5 58.9 51.4 24.5 27.0 29.0 20.9 17.6 29.9 36.8 26.0 23.3 19.1 27.4 46.0 29.8 27.7 28.6 24.0 40.1 30.7 43.6 33.8 20.9 53.3 22.1 25.5 42.6 31.6 26.5 30.7 24.4 26.3 25.4 36.6 28.5 37.4 29.5 35.2 23.9 21.9 35.4 32.9 25.9 11.8 39.5 34.3 26.7 8.1 3.3 14.7 5.6 6.8 7.1 1.4 30.8 15.7 23.0 44.6 14.8 36.0 16.0 21.7 22.0 10.1 17.5 11.5 19.8 20.7 15.9 25.9 17.5 22.3 21.5 27.4 21.6 30.2 14.7 20.6 21.9 9.0 16.0 15.2 11.7 34.7 30.8 17.4 41.5 29.1 18.8 18.9 14.5 38.4 17.2 15.7 16.0 15.9 12.7 6.7 16.0 22.3 25.4 15.1 17.0 28.0 10.0 17.7 19.5 10.5 27.1 22.0 27.8 16.6 28.4 15.7 15.2 22.7 24.8 19.2 30.5 16.5 19.7 26.2 8.5 10.5 2.1 6.8 7.1 2.0 5.6 6.4 4.9 6.1 1.3 8.1 6.8 5.7 14.7 6.8 5.6 3.3 4.5 1.4 51.9 54.4 58.9 51.4 46.0 29.8 30.7 43.6 42.6 35.4 107.2 86.7 52.8 42.9 64.5 144.1 0.0 63.7 61.6 70.5 0.0 265.1 31.5 0.0 0.0 86.9 51.4 61.9 23.3 0.0 23.6 49.2 69.4 73.0 70.0 33.8 74.7 86.1 95.8 62.6 94.2 73.4 62.1 62.4 0.0 53.3 63.6 0.0 48.9 59.4 0.0 132.6 25.8 55.6 20.2 36.6 81.8 42.6 117.6 48.7 51.0 MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467184-129768007 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Hepatocytes: 419.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: AB_2674171, HPA032136: AB_2674172, HPA069497: AB_2732134" "unprognostic (1.10e-1)" "prognostic favorable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" 11.7 11.3 7.4 15.5 7.6 7.1 11.3 3.5 9.1 8.3 12.2 10.0 19.6 10.8 15.3 17.1 9.9 15.2 14.1 10.5 7.1 7.1 12.6 45.6 7.5 11.6 8.6 6.6 12.3 16.5 5.7 5.8 4.5 9.2 11.2 3.4 11.8 14.9 24.5 14.4 9.2 9.6 10.9 8.1 8.6 9.9 11.7 3.9 16.0 10.2 14.9 14.7 12.6 13.0 20.3 17.7 6.5 15.3 18.2 21.2 16.6 0.0 2.5 2.7 13.0 5.7 11.8 10.2 5.7 6.4 4.2 4.1 15.8 16.9 11.8 9.2 7.4 0.0 7.7 1.7 6.1 1.9 0.0 1.0 2.3 5.8 10.1 8.8 0.2 6.8 7.5 0.0 2.4 0.0 0.0 0.0 20.0 0.0 8.3 5.1 21.3 9.3 12.1 0.6 10.9 10.2 10.8 0.0 4.6 7.8 5.8 2.7 6.8 6.9 2.8 0.0 2.2 11.2 9.2 0.0 5.5 2.8 0.0 0.0 0.0 0.0 6.0 0.0 3.8 0.0 2.6 15.3 6.5 19.1 14.8 18.6 20.3 17.5 17.8 15.8 19.9 17.6 18.9 1.8 18.2 13.7 17.7 21.2 16.6 7.4 7.6 3.5 9.1 7.1 7.1 8.6 6.6 9.2 3.9 11.9 14.7 57.0 56.4 45.4 15.7 37.8 86.6 57.6 15.9 97.7 7.9 41.1 107.8 40.8 70.9 48.0 68.8 23.3 51.1 53.2 48.9 49.8 64.5 419.1 76.3 14.3 52.4 98.2 75.3 90.6 62.5 39.9 62.4 45.9 56.4 33.9 74.4 47.0 51.9 227.8 39.0 45.3 55.7 43.1 97.3 37.3 22.4 67.1 59.6 48.8 MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 16.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 16.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Supported "Endoplasmic reticulum,Vesicles" NA NA Vesicles "Endoplasmic reticulum" "HPA007653: AB_1846304, HPA008033: " "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (4.24e-1)" "unprognostic (1.26e-2)" "unprognostic (9.96e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (9.47e-2)" "unprognostic (6.41e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "unprognostic (1.79e-1)" "unprognostic (5.04e-2)" 18.7 23.1 22.9 24.0 24.3 29.7 19.9 43.1 37.6 16.3 16.6 28.7 16.8 28.9 23.7 13.8 14.7 20.9 20.2 20.7 24.3 18.6 15.9 30.4 21.6 22.2 27.9 21.5 21.3 34.9 19.7 21.5 18.8 18.6 19.0 11.6 20.7 23.8 22.9 29.9 13.5 28.6 20.0 17.2 26.2 25.2 11.5 24.5 12.9 19.7 10.4 11.0 18.7 14.2 1.7 4.1 16.6 3.9 1.4 3.3 2.9 5.3 25.4 13.2 13.4 7.9 7.7 17.9 11.4 8.1 9.6 8.2 16.7 12.8 15.7 14.8 13.8 7.2 8.5 10.4 9.4 2.9 21.8 11.6 8.6 17.7 23.0 14.5 12.4 21.4 14.3 6.1 13.4 5.7 6.9 9.2 10.4 12.5 11.5 6.6 23.3 12.9 16.6 19.4 7.5 11.1 23.7 6.9 21.1 8.5 15.6 21.1 17.5 19.0 20.5 11.4 6.6 12.4 12.3 16.2 18.0 10.0 50.5 9.8 18.3 14.2 10.6 7.6 12.5 12.9 4.5 3.5 3.4 2.7 3.9 2.5 1.4 1.5 2.3 2.3 1.7 3.3 2.0 16.6 1.4 2.4 4.1 1.7 2.9 22.9 24.3 43.1 37.6 24.3 18.6 27.9 21.5 18.6 24.5 23.8 30.6 16.0 25.4 8.1 26.6 8.9 20.4 5.3 6.8 17.4 41.2 19.1 5.0 16.7 16.3 14.6 24.5 0.0 19.7 14.0 16.1 20.3 13.9 27.7 25.8 23.8 35.5 14.1 21.9 20.6 24.7 20.4 20.3 31.5 18.9 21.5 25.2 18.6 23.3 11.0 28.4 0.0 13.7 9.6 11.8 14.3 28.6 21.3 18.7 22.0 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" NA NA "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 12.1 9.1 15.3 7.9 20.6 5.9 15.7 16.1 17.4 16.6 10.9 16.3 9.7 6.9 19.1 13.7 11.4 11.5 12.0 9.4 16.3 12.9 15.7 14.1 10.1 9.6 17.4 16.5 17.2 11.7 18.4 11.5 14.9 15.5 14.7 10.1 14.6 12.0 12.6 9.6 12.5 8.4 17.9 13.8 9.4 10.7 11.5 18.1 13.9 19.1 9.8 10.6 13.0 13.8 1.2 1.2 3.5 1.7 2.5 2.0 0.6 8.5 3.4 16.8 11.7 9.0 10.8 4.0 6.9 7.8 5.0 7.3 5.0 3.2 7.3 6.4 9.6 5.4 5.8 9.7 9.4 11.3 9.6 4.5 8.2 4.4 6.9 7.3 16.6 3.5 6.9 10.4 5.8 14.9 7.3 12.4 2.9 11.2 21.7 7.7 4.2 8.0 6.3 4.2 5.3 4.5 52.4 13.9 18.1 8.5 7.6 5.5 13.6 11.9 5.6 6.1 8.9 3.9 10.9 10.6 12.8 6.4 5.3 9.2 11.4 4.0 11.3 5.4 10.6 7.6 3.5 1.7 0.6 1.0 0.9 1.2 1.2 1.5 1.0 0.6 0.6 1.2 0.9 1.5 2.5 0.5 1.2 2.0 0.6 15.3 20.6 16.1 17.4 16.3 12.9 17.4 16.5 15.5 18.1 44.7 17.7 5.9 14.0 19.5 29.4 15.1 20.4 21.4 34.2 15.7 23.6 10.7 3.3 11.3 3.3 22.5 10.5 0.0 11.2 6.2 22.6 33.3 13.9 26.3 10.8 14.3 23.1 21.5 18.7 3.7 19.0 11.5 25.3 5.4 15.4 16.5 16.7 5.8 23.3 14.4 14.7 0.0 23.4 16.7 11.5 21.5 21.2 10.1 9.4 14.4 MIB2 "FLJ39787, skeletrophin, ZZANK1, ZZZ5" ENSG00000197530 "Mindbomb E3 ubiquitin protein ligase 2" Q96AX9 1 1615415-1630610 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 72.5" "Cell type enhanced" "Detected in many" 8 "Basal keratinocytes: 116.3;Late spermatids: 190.0;Suprabasal keratinocytes: 110.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 13.4;SCLC-21H: 14.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068322 Enhanced NA NA "HPA068322: AB_2685973" "unprognostic (3.93e-2)" "unprognostic (6.02e-2)" "unprognostic (2.34e-2)" "unprognostic (6.60e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (6.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.17e-2)" "unprognostic (2.22e-3)" "unprognostic (1.29e-1)" "unprognostic (3.58e-2)" "unprognostic (2.49e-1)" "unprognostic (1.01e-2)" 6.4 3.9 8.7 6.4 10.0 4.5 4.7 8.8 11.5 4.8 6.9 7.1 4.7 5.3 5.1 5.4 11.4 4.1 3.7 6.1 9.1 7.9 5.5 6.2 5.1 3.7 5.3 7.1 5.8 7.0 3.7 9.4 4.0 5.7 4.7 3.7 6.6 5.4 6.5 72.5 9.6 4.6 5.4 3.4 9.0 8.5 5.2 5.8 7.4 5.9 9.7 4.1 4.5 4.1 2.9 9.2 1.9 0.1 7.3 4.7 1.0 6.6 0.9 0.4 1.5 1.8 0.6 9.3 3.1 1.4 1.0 2.3 1.3 1.7 0.7 4.5 0.9 0.4 13.4 0.5 2.1 0.0 3.5 5.7 0.5 1.9 1.3 2.4 0.8 2.2 1.4 1.4 0.6 0.2 0.6 0.5 3.1 2.7 1.2 0.3 1.0 3.6 8.4 1.2 1.7 10.6 6.2 1.9 9.1 0.1 0.8 14.3 5.2 5.3 0.8 5.1 0.3 1.0 3.3 0.6 1.0 2.2 5.2 0.9 6.9 2.0 1.8 2.4 2.7 1.1 0.0 0.1 1.9 4.3 0.1 4.3 2.6 3.3 4.7 0.0 2.9 3.9 2.9 0.5 7.3 0.0 9.2 2.3 1.0 8.7 10.0 8.8 11.5 9.1 7.9 5.3 7.1 5.7 5.8 0.0 9.6 13.2 14.2 116.3 32.0 9.8 12.7 4.0 7.9 22.7 11.8 8.6 8.3 6.8 52.0 10.0 36.6 0.0 1.1 7.0 10.3 10.7 20.7 9.2 5.8 25.4 14.5 13.5 6.2 190.0 19.5 6.4 16.9 3.6 25.0 25.0 5.9 42.1 14.9 18.1 35.7 0.0 16.8 22.9 43.2 110.2 12.6 52.2 28.9 15.9 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Horizontal cells: 65.2;Ito cells: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 57.2;AF22: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002878, HPA003715" Approved Approved "Centriolar satellite" NA NA "Centriolar satellite" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 13.4 3.6 6.5 10.4 8.4 0.3 8.6 16.3 7.1 17.5 21.5 3.8 11.7 7.7 17.9 11.3 12.2 7.7 13.1 13.2 6.2 4.2 7.9 4.9 10.4 4.2 4.5 3.7 12.0 4.8 2.7 6.6 7.8 4.9 14.6 12.8 15.9 7.1 19.1 2.8 3.9 8.7 30.6 2.6 1.3 5.3 6.5 4.1 0.8 6.2 7.1 5.8 17.1 20.5 1.0 0.7 3.3 0.0 0.0 0.1 0.1 12.3 57.2 43.3 6.6 2.5 3.6 5.3 7.7 6.5 8.0 8.2 10.5 3.7 4.2 2.5 7.0 22.4 8.5 3.5 5.4 6.0 0.2 5.2 0.9 8.1 0.2 1.1 0.0 0.2 4.1 2.8 5.2 5.5 7.5 7.6 1.9 0.6 0.7 3.1 2.0 1.6 0.1 13.8 1.6 4.2 1.2 11.0 0.0 5.9 11.4 3.0 1.1 3.3 9.8 3.6 14.6 6.8 0.0 4.8 2.6 0.3 13.4 6.8 0.6 0.3 0.1 5.7 0.0 12.9 0.1 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.1 6.5 8.4 16.3 5.2 6.2 4.2 4.5 3.7 4.9 4.1 32.8 16.5 0.0 25.6 19.1 7.7 4.1 7.6 14.7 21.6 22.7 17.7 7.1 1.7 12.3 1.5 24.5 14.4 0.0 7.5 22.8 11.8 5.9 1.1 5.4 1.4 65.2 11.6 85.3 4.4 4.5 27.9 1.1 3.3 0.0 8.1 44.8 5.7 14.4 38.9 1.4 2.5 6.5 2.3 0.2 1.9 8.8 16.7 0.0 18.0 51.2 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833388-4898061 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved NA NA "HPA056296: AB_2683090" "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favorable (2.77e-4)" "prognostic unfavorable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 12.7 14.8 31.4 18.2 46.8 14.9 14.2 30.8 43.5 15.2 26.0 32.6 8.8 33.1 12.4 7.7 40.0 14.3 15.6 9.0 28.4 12.8 13.8 10.0 23.3 17.1 28.6 27.3 27.5 21.5 16.5 15.4 17.4 29.0 14.3 20.7 14.5 21.1 11.3 8.3 47.3 31.1 11.4 24.8 20.0 22.3 14.5 30.9 9.0 12.7 14.6 16.8 14.9 24.1 2.6 1.2 6.4 1.6 0.3 3.0 2.3 18.8 34.5 8.0 13.1 12.8 9.3 23.2 15.0 13.8 12.0 10.1 13.1 13.1 13.4 17.4 15.8 11.9 38.2 6.0 27.1 5.9 19.3 16.8 9.6 21.9 10.2 8.4 3.5 18.8 9.9 20.3 11.3 10.5 10.2 13.0 4.5 10.3 11.7 8.8 11.2 5.7 8.1 6.3 12.3 11.2 7.2 6.7 8.1 18.4 19.3 8.4 6.7 15.6 13.0 9.8 9.2 11.7 4.9 18.7 12.8 5.8 21.7 14.3 6.7 5.4 2.7 11.5 7.7 8.6 0.0 1.6 6.4 2.7 1.6 3.0 2.6 2.8 2.1 1.2 1.5 2.0 0.8 1.3 0.3 0.8 0.8 2.8 2.3 31.4 46.8 30.8 43.5 28.4 12.8 28.6 27.3 29.0 30.9 0.0 1.3 1.9 12.1 36.5 6.4 1.4 12.7 1.4 3.4 5.2 37.3 15.1 5.0 7.8 2.6 8.8 31.0 0.0 9.0 10.5 7.3 11.7 8.1 8.1 17.6 12.7 18.0 13.5 12.1 5.4 15.0 8.8 15.1 45.1 29.6 6.5 11.9 42.1 13.8 7.5 15.5 12.9 4.4 5.0 9.4 52.9 16.4 6.9 27.3 18.7 MKNK1 MNK1 ENSG00000079277 "MAP kinase interacting serine/threonine kinase 1" Q9BUB5 1 46557408-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.3" "Cell type enhanced" "Detected in all" 6 "Hofbauer cells: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: AB_2686382" "unprognostic (4.05e-3)" "prognostic favorable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 17.6 12.0 10.7 16.2 10.5 16.8 12.1 13.7 12.3 9.2 12.6 11.0 9.6 9.7 11.9 13.3 12.2 11.1 11.4 12.3 10.8 7.0 9.4 10.8 16.1 16.3 9.9 9.8 10.7 72.3 8.6 11.3 15.4 11.0 9.9 13.3 11.9 10.6 7.7 12.8 10.2 12.7 13.3 8.1 25.6 11.7 7.6 8.7 12.5 8.8 15.8 10.9 10.9 14.5 4.9 6.0 33.3 12.1 5.0 22.0 6.1 19.5 13.2 8.8 9.7 7.9 11.7 11.7 9.9 9.9 12.0 16.4 15.3 8.0 12.9 12.2 9.9 13.5 23.7 14.7 16.2 12.9 22.2 13.0 27.3 15.2 13.0 12.3 14.6 22.2 15.4 11.2 15.6 8.6 6.5 14.0 15.9 14.2 9.5 6.5 12.8 10.4 13.0 6.0 11.3 15.7 9.6 18.4 12.9 12.9 20.5 6.2 5.5 19.1 17.3 16.0 18.3 11.7 16.3 11.4 4.4 0.9 13.6 11.0 8.1 13.5 11.0 8.5 18.8 8.0 3.9 12.1 14.3 7.5 11.5 22.0 4.6 6.6 6.8 6.0 4.9 4.8 7.0 33.3 5.0 8.1 4.4 4.4 6.1 10.7 10.5 13.7 12.3 10.8 7.0 9.9 9.8 11.0 8.7 11.9 22.1 17.5 15.7 12.4 17.9 15.5 15.3 10.7 18.2 21.0 2.0 19.4 6.6 16.1 13.0 14.3 23.5 23.3 32.1 29.7 19.5 15.8 11.5 20.2 113.5 17.5 16.1 18.4 71.2 17.5 19.8 58.2 10.1 16.2 11.9 6.5 28.0 14.0 34.3 10.2 4.6 6.5 14.4 16.8 15.5 9.7 15.4 24.9 14.7 19.5 MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAP kinase interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" No No "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: AB_2732157" "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favorable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favorable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" 30.3 15.6 7.6 24.2 8.5 31.9 31.1 16.6 9.7 12.5 22.7 6.5 21.4 13.1 9.3 18.4 42.1 11.0 21.7 33.3 7.5 5.7 10.3 22.0 24.5 16.9 10.3 3.3 13.8 53.1 8.3 13.4 16.7 9.2 18.8 8.4 14.2 35.2 32.5 207.5 19.3 15.1 13.0 7.0 27.8 16.7 9.1 9.1 16.0 32.3 47.1 32.8 21.2 63.6 10.7 5.9 26.9 8.0 6.1 7.5 2.2 13.4 15.1 6.4 14.1 47.8 17.4 14.4 7.9 5.7 5.7 5.8 9.7 23.5 19.0 11.0 16.0 5.9 16.6 8.1 23.2 2.6 25.8 7.5 7.7 12.7 10.3 80.4 15.0 13.8 18.4 56.5 10.8 23.0 13.3 13.5 12.8 13.1 34.0 3.9 7.8 8.9 12.5 16.8 10.2 16.5 17.2 1.8 23.9 10.1 8.7 8.9 10.6 18.7 27.6 34.0 7.5 11.4 18.6 20.2 2.1 8.2 8.4 9.5 55.3 21.4 18.5 16.8 11.3 3.8 2.7 6.1 5.7 5.6 6.3 5.1 10.7 5.8 6.2 4.8 10.2 3.7 4.5 26.9 6.1 8.0 5.9 7.5 2.2 7.6 8.5 16.6 9.7 7.5 5.7 10.3 3.3 9.2 9.1 35.7 53.3 43.1 91.9 73.3 45.8 46.4 30.6 16.0 11.4 34.9 23.6 21.3 8.3 25.3 6.2 35.4 94.0 23.3 48.2 31.0 32.0 121.4 28.8 50.0 30.9 39.7 144.2 58.3 34.6 10.0 18.7 27.4 54.0 19.8 92.4 38.7 46.8 69.1 19.1 18.2 43.0 19.4 34.0 15.5 21.8 102.4 47.3 39.5 64.3 110.6 MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453040-140479569 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000567 Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA000567: AB_1079299" "unprognostic (9.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.41e-1)" "unprognostic (4.87e-3)" "unprognostic (1.24e-2)" "unprognostic (8.02e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-3)" "unprognostic (5.76e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.22e-2)" 16.8 17.6 26.8 20.8 28.8 69.9 20.1 37.2 32.6 20.4 39.6 16.1 19.7 28.4 20.1 18.6 23.3 22.2 22.4 38.5 24.9 29.8 20.6 17.5 23.6 18.3 25.7 23.3 24.9 27.3 28.2 21.5 31.7 29.4 21.0 33.7 19.4 24.8 23.1 38.5 24.4 26.6 26.3 20.5 22.5 21.7 95.4 20.2 21.0 23.6 18.8 22.3 25.3 36.4 13.1 7.5 39.3 10.5 12.8 17.8 6.4 28.4 22.0 17.2 25.5 27.3 23.9 24.3 19.6 25.5 15.5 17.9 9.0 30.0 20.7 30.8 19.1 31.0 13.9 19.3 21.6 19.7 40.9 16.7 21.5 13.2 16.6 22.0 18.4 33.2 23.8 32.6 17.4 16.5 25.6 15.4 14.3 16.9 26.1 14.8 24.5 21.5 32.9 44.2 24.0 16.3 15.6 14.7 31.6 24.8 33.0 23.8 24.6 24.6 33.4 35.1 26.5 16.4 16.0 21.8 10.9 8.7 26.5 17.9 62.3 45.6 18.1 31.2 28.9 22.4 19.4 9.2 39.3 6.7 8.7 8.0 13.1 13.0 10.1 7.5 10.9 17.8 11.3 18.1 12.8 10.5 2.5 14.0 6.4 26.8 28.8 37.2 32.6 24.9 29.8 25.7 23.3 29.4 20.2 47.6 30.4 57.3 58.0 72.9 58.8 51.3 63.7 33.5 43.3 40.1 33.4 63.4 87.9 55.8 227.6 33.8 112.4 256.9 59.7 76.6 47.0 74.5 36.9 38.9 53.2 112.8 93.6 40.5 91.7 263.0 61.5 68.3 65.8 87.4 100.7 52.1 52.9 123.8 58.7 39.1 43.2 45.3 49.5 153.2 47.1 83.4 115.4 66.0 96.2 100.8 MKRN2 "HSPC070, RNF62" ENSG00000075975 "Makorin ring finger protein 2" Q9H000 3 12557014-12583713 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Early spermatids: 562.3;Late spermatids: 587.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037559, HPA037560" Enhanced Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA037559: AB_10672460, HPA037560: AB_10696936" "unprognostic (4.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-2)" "unprognostic (5.99e-2)" "unprognostic (3.89e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (4.38e-1)" "unprognostic (8.49e-2)" "unprognostic (2.86e-1)" "unprognostic (1.42e-1)" "unprognostic (2.56e-3)" "prognostic favorable (6.04e-4)" "unprognostic (3.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.33e-2)" "unprognostic (3.32e-2)" 13.7 10.4 15.1 11.1 18.3 16.4 11.6 29.3 19.5 13.7 12.7 12.4 16.1 12.5 15.2 12.3 16.2 13.1 10.9 26.3 14.0 15.1 13.7 12.5 12.1 12.6 15.2 14.8 20.8 26.6 17.3 11.9 14.4 16.0 11.3 11.5 13.2 12.8 13.1 24.5 12.8 10.9 15.9 16.2 10.1 11.7 46.1 14.7 15.4 18.2 17.0 13.7 13.0 12.6 21.3 19.0 30.0 20.3 25.3 26.2 18.7 10.7 12.5 14.9 11.2 23.3 22.7 28.8 16.7 17.9 21.3 17.9 12.0 10.7 15.3 9.6 18.4 9.8 6.6 19.3 16.4 19.0 17.3 16.3 21.8 14.3 16.1 26.9 21.4 9.9 25.2 15.3 24.8 15.6 19.1 17.4 21.3 20.3 21.7 18.3 15.2 26.2 11.1 9.9 10.5 22.0 25.3 14.4 17.2 14.9 14.3 8.7 14.8 14.5 7.4 14.8 11.0 16.8 19.0 17.6 14.6 14.3 17.3 22.6 16.5 33.7 32.8 15.8 25.7 21.9 18.9 17.2 30.0 21.5 15.6 26.2 21.3 22.1 22.0 19.0 16.4 23.9 22.3 15.0 25.3 20.3 15.1 23.4 18.7 15.1 18.3 29.3 19.2 14.0 15.1 15.2 14.8 16.0 14.7 17.9 8.1 9.3 8.8 8.5 14.5 12.1 2.5 17.4 11.4 5.2 3.9 16.1 16.6 13.6 562.3 11.6 7.3 0.0 14.7 16.7 10.4 6.8 18.5 5.4 13.3 11.1 2.4 6.7 9.8 587.8 19.0 7.9 15.1 24.4 11.9 18.1 12.7 12.9 19.4 8.1 12.4 12.9 14.7 60.0 42.8 8.2 13.5 9.6 11.4 7.9 MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565678-23630075 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell type enhanced" "Detected in some" 19 "Bipolar cells: 12.6;Cone photoreceptor cells: 23.6;Horizontal cells: 6.4;Rod photoreceptor cells: 6.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 4 "T-cells: 5.7" "Cell line enhanced" "Detected in many" "JURKAT: 16.0;K-562: 17.1" "Low region specificity" "Detected in many" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: AB_10603873" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (4.26e-1)" "unprognostic (1.86e-3)" "unprognostic (1.04e-3)" "unprognostic (1.15e-2)" "unprognostic (6.27e-4)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.97e-3)" "unprognostic (2.86e-1)" "unprognostic (1.05e-4)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (8.91e-2)" "unprognostic (9.78e-2)" 1.0 0.7 5.1 1.2 10.4 4.0 1.2 1.0 11.1 0.5 1.1 8.4 0.0 1.3 1.3 3.2 5.6 0.9 0.8 0.8 6.4 3.4 1.1 0.7 1.0 1.9 14.4 3.0 1.2 1.7 0.5 3.8 8.5 5.1 1.2 0.8 3.1 5.2 1.0 1.4 1.2 1.9 0.8 8.2 1.5 0.9 5.7 13.3 5.0 0.9 1.1 1.7 0.7 0.6 1.0 0.9 1.3 0.5 0.4 5.7 0.7 4.6 3.3 3.0 3.1 0.0 0.0 7.0 0.3 0.0 2.8 1.9 8.3 0.0 0.2 0.1 0.0 6.2 8.0 1.3 0.0 0.7 0.0 0.3 6.7 8.9 0.3 0.1 7.8 6.0 0.1 0.0 5.8 0.0 1.2 0.0 16.0 17.1 7.3 0.8 0.0 8.2 3.4 0.0 4.4 10.1 5.9 1.1 4.1 0.0 0.1 0.7 2.4 0.0 3.4 0.0 0.2 2.6 2.3 0.0 7.8 6.6 0.4 5.5 9.2 11.3 5.5 4.5 0.1 0.1 1.3 0.5 0.4 1.8 0.2 1.0 1.0 0.6 1.4 0.2 0.9 2.0 5.7 1.3 0.4 0.3 0.9 0.4 0.7 5.1 10.4 1.0 6.8 6.4 3.4 14.4 3.0 5.1 13.3 0.0 0.0 0.0 1.1 0.5 12.6 0.4 0.0 0.0 0.0 0.0 23.6 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 3.4 0.0 0.0 0.4 0.0 6.4 0.0 1.2 2.4 1.0 0.0 0.5 0.0 0.0 0.4 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 50.4" "Cell type enhanced" "Detected in many" 6 "granulocytes: 27.8;Macrophages: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 18.5 4.7 5.2 15.1 8.9 21.6 13.2 2.9 7.9 6.4 8.0 3.2 5.3 8.5 7.5 3.8 11.5 5.2 9.1 6.8 6.4 3.5 7.4 6.7 17.3 14.8 10.5 1.8 2.8 8.2 1.6 3.0 7.1 8.1 6.3 9.2 6.5 12.6 4.3 2.3 3.6 10.0 6.0 11.2 26.2 8.2 1.9 8.4 4.3 6.5 4.9 10.4 9.2 50.4 4.2 9.2 25.2 17.7 1.7 8.1 7.1 6.5 12.2 0.1 0.1 3.2 6.7 0.1 8.5 7.4 8.0 11.9 7.0 13.2 0.1 9.8 7.2 6.9 10.5 2.2 12.2 3.0 4.1 0.3 9.2 9.1 8.0 2.3 6.0 9.6 4.5 1.2 8.5 3.0 4.7 19.3 10.7 1.3 1.3 6.2 10.9 3.4 12.0 1.1 14.3 15.0 6.7 0.9 11.7 11.4 4.8 0.5 0.4 6.7 4.5 3.7 0.0 3.2 6.3 21.0 4.0 2.4 3.6 5.8 5.7 19.2 1.6 7.3 21.2 1.9 8.3 17.7 21.7 5.8 10.6 7.9 4.2 6.5 6.0 9.2 2.8 3.6 5.5 25.2 1.7 10.2 0.5 8.1 7.1 5.2 8.9 2.9 7.9 6.4 3.5 10.5 1.8 8.1 8.4 3.0 15.4 8.1 4.8 3.1 0.0 1.6 2.5 2.7 7.9 1.8 0.0 0.2 1.7 4.0 2.6 17.9 5.8 0.0 4.6 0.5 3.8 2.0 27.8 0.9 14.2 1.6 1.2 14.7 15.5 3.8 0.9 24.1 6.8 1.0 5.6 0.0 4.1 9.1 0.4 0.3 0.4 0.0 3.3 0.0 0.2 2.5 0.2 10.0 6.4 5.1 MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305200 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "testis: 45.0" "Cell type enhanced" "Detected in many" 13 "Ciliated cells: 214.2;Cone photoreceptor cells: 174.7;Early spermatids: 171.0;Rod photoreceptor cells: 441.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBF TERT88: 28.6;hTEC/SVTERT24-B: 72.8;NB-4: 90.6;U-138 MG: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027292 Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA027292: AB_10600989" "unprognostic (8.16e-2)" "unprognostic (1.82e-1)" "unprognostic (6.68e-2)" "unprognostic (6.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (4.43e-2)" "unprognostic (3.49e-4)" "unprognostic (2.19e-1)" "unprognostic (2.03e-2)" "unprognostic (2.93e-1)" "unprognostic (3.01e-3)" "unprognostic (5.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.48e-1)" 5.9 6.8 12.9 2.7 17.3 3.7 7.8 9.7 15.9 7.6 3.6 8.7 6.2 4.7 7.6 10.2 3.9 26.4 6.4 8.3 13.5 10.2 7.7 3.6 6.1 2.5 6.0 13.7 12.4 8.6 9.4 22.1 3.6 16.6 5.1 3.0 15.2 6.1 5.4 1.9 8.6 4.1 5.9 6.2 3.8 11.7 45.0 6.2 0.4 11.7 2.3 2.2 6.2 3.9 0.7 3.9 0.9 1.1 10.6 2.4 1.3 3.4 3.0 0.4 1.7 0.7 2.5 0.7 7.0 2.0 10.1 12.2 0.2 8.4 2.6 0.5 1.3 2.2 0.7 0.6 3.6 28.6 2.9 2.6 0.6 0.4 2.3 3.1 0.3 3.4 2.1 0.9 72.8 6.7 7.9 0.3 0.5 0.6 0.1 6.6 2.3 0.2 90.6 0.1 1.5 7.4 0.4 0.2 0.0 4.1 0.1 1.1 0.7 1.2 0.4 19.6 0.1 2.1 0.2 0.2 38.5 1.9 1.4 2.2 0.2 0.4 0.2 7.7 0.2 17.4 0.0 1.1 0.0 0.7 0.7 1.2 0.0 0.5 1.9 3.9 0.7 1.1 2.4 0.9 10.6 0.1 0.0 0.0 1.3 12.9 17.3 9.7 15.9 13.5 10.2 6.0 13.7 16.6 6.2 17.9 17.4 0.5 6.5 9.5 36.2 12.2 10.2 214.2 43.3 12.2 174.7 1.0 5.0 7.0 171.0 6.7 3.8 0.0 14.2 2.1 7.6 3.6 3.5 1.7 2.0 15.9 4.6 7.4 1.8 130.3 28.1 4.2 75.9 0.0 2.0 58.0 5.6 0.0 15.2 8.1 441.5 25.8 12.1 81.9 27.2 5.1 1.0 6.7 3.8 3.0 MOS ENSG00000172680 "MOS proto-oncogene, serine/threonine kinase" P00540 8 56112942-56113982 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 3.5" "Cell type enriched" "Detected in single" 8 "Early spermatids: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "unprognostic (3.28e-1)" 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 56.1;Distal tubular cells: 48.0;Exocrine glandular cells: 52.2;Proximal tubular cells: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003634 Approved Approved Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA003634: AB_1851388" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 12.4 23.4 13.9 18.4 14.8 13.7 17.6 18.1 15.7 10.6 15.2 9.8 17.5 13.1 12.5 15.1 19.4 12.5 16.3 31.2 12.2 12.0 25.7 41.7 10.2 15.2 14.3 14.0 10.5 24.2 13.5 9.1 13.9 14.0 13.6 16.3 10.1 17.7 22.5 57.3 16.5 13.4 14.8 12.9 14.6 15.1 7.6 14.0 13.2 14.8 31.2 15.7 14.3 11.6 18.3 28.9 11.2 22.0 20.0 33.5 20.9 26.1 36.9 12.3 14.1 13.3 13.2 17.2 15.5 16.9 32.4 27.6 28.3 16.5 18.2 12.8 15.4 20.0 18.7 25.2 26.7 34.3 9.3 29.9 14.3 17.5 23.5 25.1 29.8 9.8 14.2 12.8 21.5 34.5 11.0 24.6 18.9 23.0 13.3 18.3 32.7 25.7 20.5 9.3 40.8 50.0 13.3 21.9 26.5 23.8 19.4 11.5 22.0 13.4 24.5 30.1 16.5 32.8 24.6 10.4 17.5 19.2 18.4 29.2 13.9 11.0 20.1 20.0 33.4 14.4 11.2 22.0 10.5 17.3 20.7 14.9 18.3 21.1 17.2 28.9 14.8 15.7 17.6 2.0 20.0 17.4 19.4 33.5 20.9 13.9 14.8 18.1 15.7 12.2 12.0 14.3 14.0 14.0 14.0 29.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 38.8 14.8 24.4 0.0 56.1 48.0 41.8 0.0 0.0 0.0 0.0 52.2 30.7 0.0 0.0 1.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 26.2 0.0 0.0 44.8 0.0 0.0 104.5 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.0 0.0 0.0 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054268-10428891 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Cell type enriched" "Detected in many" 6 "Proximal tubular cells: 597.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 78.4" "Cell type enhanced" "Detected in many" "eosinophil: 9.0" "Group enriched" "Detected in many" 4 "dendritic cells: 2.3;granulocytes: 9.0;monocytes: 3.2" "Cell line enhanced" "Detected in many" "HMC-1: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 25000 "Nucleoplasm, Plasma membrane, Cytosol" "Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 7.0 8.1 8.0 5.2 7.5 36.1 5.9 78.4 13.7 3.6 5.9 4.3 2.2 5.9 4.8 3.7 5.5 4.2 4.4 8.5 8.9 5.5 32.4 22.9 5.7 6.8 6.8 9.5 4.2 10.2 2.9 3.4 4.6 8.1 3.4 4.0 3.9 6.0 5.0 4.7 3.8 12.7 4.9 6.7 7.2 4.9 8.5 5.5 3.5 4.4 2.6 3.8 3.9 2.7 1.1 2.3 9.0 3.2 1.1 0.8 0.3 0.1 1.1 1.8 5.4 1.6 1.8 0.6 3.3 0.7 0.5 2.2 0.7 2.7 0.0 0.8 3.0 7.2 2.9 0.5 0.2 1.7 0.4 0.0 0.5 1.7 2.5 5.3 1.0 15.2 0.5 3.9 0.4 0.0 1.8 0.9 0.3 0.5 0.3 5.9 0.2 0.0 0.3 0.8 3.9 1.0 1.8 1.7 2.3 1.3 1.3 3.1 2.0 5.4 0.2 0.7 0.6 2.8 3.3 3.2 2.2 2.6 0.5 1.6 0.2 0.1 0.9 5.9 1.0 4.1 0.8 3.2 9.0 0.7 2.2 0.6 1.1 0.8 0.5 2.3 0.4 0.6 0.5 3.8 1.1 1.6 0.3 0.5 0.3 8.0 7.5 78.4 13.7 8.9 5.5 6.8 9.5 8.1 5.5 0.0 9.0 10.0 24.1 14.5 10.7 18.1 17.8 5.3 4.5 24.4 29.5 5.8 77.9 27.0 64.1 26.4 29.0 0.0 41.4 4.5 11.3 16.9 81.6 82.9 42.3 15.9 9.2 16.5 31.0 107.2 8.6 33.1 28.7 14.4 19.7 13.4 40.7 28.8 9.2 597.4 5.8 12.9 17.6 27.7 18.8 12.3 7.0 15.3 17.4 28.6 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795281-236903981 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cardiomyocytes: 84.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol NA NA Cytosol "HPA044474: AB_10966696, HPA054915: AB_2732589" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (8.10e-2)" 14.5 11.4 9.9 13.2 13.5 7.6 13.6 14.8 14.4 16.9 16.4 16.2 16.0 7.5 18.1 27.3 10.4 18.4 16.3 21.9 9.4 9.8 21.2 9.5 11.7 14.3 12.6 12.8 24.7 20.8 27.4 12.4 17.5 13.0 14.0 8.9 17.7 11.1 17.3 27.0 15.4 11.7 23.3 12.1 13.9 14.9 20.1 12.1 20.8 22.4 11.1 13.2 18.4 14.4 3.3 1.6 3.0 2.0 2.3 5.8 2.1 9.9 6.7 8.3 6.8 15.4 14.2 9.8 8.8 7.8 9.7 10.1 6.4 7.7 22.3 8.1 9.8 5.2 6.9 10.7 7.8 11.6 10.3 9.2 13.1 9.0 11.7 10.3 20.7 8.2 20.2 4.9 12.8 12.3 7.6 12.8 12.1 18.8 10.5 8.1 6.9 10.8 6.7 11.1 8.2 3.6 11.8 14.7 14.3 7.0 11.6 6.8 18.9 9.9 7.2 8.8 6.1 10.3 8.5 16.6 16.0 6.1 12.2 11.3 22.7 7.0 13.0 10.4 13.1 15.8 2.7 1.6 3.0 3.2 2.0 5.8 2.7 4.2 4.5 1.5 3.3 5.0 4.0 0.1 2.3 1.5 1.6 2.9 2.1 9.9 13.5 14.8 14.4 9.4 9.8 12.6 12.8 13.0 12.1 53.6 31.2 20.1 6.8 7.2 0.0 84.0 20.4 20.1 13.6 38.4 0.0 19.3 1.7 11.9 5.3 12.8 6.3 0.0 12.8 7.8 17.5 8.3 29.0 9.6 12.6 0.0 8.1 15.4 16.5 4.2 22.2 10.4 10.1 10.8 7.3 0.0 11.7 10.5 31.1 5.7 0.0 6.5 15.5 14.9 19.7 4.4 18.9 11.7 12.1 4.8 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 2: 57.4;Late spermatids: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 12.2 12.3 11.2 10.5 13.8 5.4 9.7 15.6 14.3 10.8 10.4 24.1 11.5 10.3 17.3 15.9 10.5 11.3 13.3 15.8 14.2 12.9 22.0 23.9 14.9 11.4 18.1 9.6 13.6 13.6 9.4 13.1 11.6 16.6 10.8 11.9 13.6 11.3 7.4 34.6 10.5 11.5 14.2 22.1 9.3 9.2 8.4 12.5 8.1 14.7 9.9 13.5 13.6 8.8 4.6 4.8 4.6 6.8 3.4 11.4 4.2 9.4 8.9 4.7 10.5 18.2 5.9 13.5 14.7 8.7 7.3 8.4 13.4 7.6 15.9 14.1 11.8 14.0 6.1 7.3 7.2 13.9 10.1 8.2 7.6 31.0 7.1 11.1 11.6 3.3 9.5 6.6 12.4 9.1 10.4 4.7 4.1 9.9 12.1 4.3 1.8 7.4 5.9 3.6 14.0 9.9 6.1 5.1 6.7 7.9 7.4 7.4 1.0 25.8 18.8 16.2 9.7 5.8 9.0 7.3 17.1 10.8 13.1 11.5 18.0 5.9 13.1 12.4 25.6 9.1 4.6 5.1 4.1 5.5 6.8 9.5 4.6 9.2 7.9 4.8 4.1 5.4 5.1 0.1 3.4 5.4 2.7 11.4 4.2 11.2 13.8 15.6 14.3 14.2 12.9 18.1 9.6 16.6 12.5 14.9 57.4 8.2 7.5 14.4 0.0 10.1 2.5 9.4 11.4 8.7 0.0 8.3 18.3 8.0 40.0 7.0 8.5 0.0 4.9 7.5 10.2 9.9 10.3 16.6 6.7 0.0 9.2 10.4 12.5 61.7 9.8 8.7 1.7 5.4 9.6 0.0 5.8 7.0 11.0 23.3 0.0 6.5 13.3 16.9 11.9 18.1 9.4 12.9 8.9 7.0 MUL1 "C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218" ENSG00000090432 "Mitochondrial E3 ubiquitin protein ligase 1" Q969V5 1 20499448-20508161 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026827 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Mitochondria, Cytosol" "HPA026827: AB_10601137" "unprognostic (1.39e-1)" "unprognostic (2.73e-2)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (6.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.31e-2)" "unprognostic (5.86e-3)" "unprognostic (4.05e-1)" "unprognostic (9.10e-2)" "prognostic favorable (6.15e-14)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (2.37e-1)" 13.3 15.9 10.3 12.9 12.3 20.6 20.4 9.2 22.2 13.1 15.8 19.0 8.0 11.6 18.2 10.7 17.2 17.0 18.5 26.2 11.7 12.5 20.5 20.1 16.3 12.1 16.8 9.5 17.5 26.8 21.9 13.0 21.6 17.6 13.9 13.3 14.3 15.3 18.1 26.7 17.4 19.5 17.0 11.7 13.6 15.2 14.1 11.6 18.5 15.1 14.6 14.0 16.3 13.6 23.2 26.0 31.9 30.4 25.2 32.1 27.5 17.1 16.6 9.6 19.8 20.8 11.7 10.4 17.0 20.4 21.2 20.5 10.2 28.5 12.9 19.1 24.0 16.1 26.1 17.2 24.6 15.5 12.8 13.6 9.9 11.2 14.8 24.5 13.5 17.0 19.1 32.5 21.7 22.6 12.5 13.8 11.7 12.9 15.8 23.0 8.7 8.1 9.1 9.8 14.3 15.9 8.0 12.1 16.7 25.0 9.6 9.8 14.5 15.3 16.4 20.9 8.1 11.5 13.0 15.6 20.7 11.9 18.0 15.2 18.5 16.1 13.9 16.2 18.4 19.1 26.3 26.5 31.9 30.9 30.4 32.1 23.2 23.6 31.4 26.0 21.5 27.1 26.3 24.0 25.2 25.4 20.1 32.1 27.5 10.3 12.3 9.2 22.2 11.7 12.5 16.8 9.5 17.6 11.6 20.8 9.3 11.7 7.8 4.6 12.5 14.6 12.7 9.4 6.8 17.4 5.9 33.7 10.0 21.4 1.6 9.7 12.0 0.0 20.3 20.8 12.1 8.1 3.5 11.9 19.7 12.7 8.2 10.4 11.4 2.8 12.0 7.7 18.6 21.6 11.8 15.6 19.7 11.5 14.5 8.7 10.5 19.4 8.5 10.6 13.4 6.1 31.5 10.8 10.1 9.0 MYCBP2 "FLJ10106, KIAA0916, PAM" ENSG00000005810 "MYC binding protein 2, E3 ubiquitin protein ligase" O75592 13 77044655-77327050 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 40.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA058807: AB_2732627" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 28.0 13.4 31.0 26.1 28.8 24.1 22.4 31.3 32.7 15.5 10.9 8.1 11.5 8.0 16.2 26.7 18.9 11.7 11.1 13.5 24.1 18.6 12.3 13.2 12.4 29.8 15.3 31.1 22.8 12.6 14.5 17.2 9.6 20.0 17.9 11.5 9.6 12.9 12.4 13.7 57.6 13.6 13.2 14.0 24.1 10.3 14.1 16.2 18.6 11.6 12.6 30.7 13.3 34.0 8.3 4.6 3.3 3.7 4.2 7.3 2.5 7.8 4.0 4.9 5.3 24.5 10.9 2.8 5.0 7.4 4.4 5.7 3.5 4.1 22.5 3.2 9.8 4.3 7.3 8.4 9.2 6.0 8.9 8.3 19.1 8.2 7.3 8.3 40.0 6.8 12.2 7.7 4.0 8.0 4.3 9.9 8.3 4.0 7.1 7.8 4.7 10.9 27.0 2.6 10.5 5.1 12.5 5.0 5.4 7.4 7.8 7.7 3.6 6.0 8.7 4.5 5.2 3.2 30.7 13.0 4.2 3.5 2.7 4.8 7.7 5.3 16.1 8.5 33.0 4.2 2.0 3.5 3.2 5.8 3.7 5.1 7.9 6.5 5.0 3.2 8.3 7.3 5.8 3.3 4.2 2.5 4.6 7.3 2.5 31.0 28.8 31.3 32.7 24.1 18.6 15.3 31.1 20.0 16.2 35.7 43.3 79.8 35.8 73.2 212.4 65.7 30.6 17.4 26.1 33.2 98.2 33.8 1.7 22.3 46.1 82.8 12.8 23.3 28.6 26.5 62.0 42.9 47.3 46.5 37.4 206.6 31.4 39.3 93.9 20.0 60.9 48.5 30.4 37.9 18.1 141.3 26.4 17.5 90.5 11.2 95.1 103.5 74.0 61.5 64.3 131.7 36.7 68.3 24.7 36.1 MYLIP "IDOL, MIR" ENSG00000007944 "Myosin regulatory light chain interacting protein" Q8WY64 6 16129125-16148248 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 84.0" "Cell type enhanced" "Detected in many" 7 "Syncytiotrophoblasts: 294.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 33.8" "Low region specificity" "Detected in all" NA NA "unprognostic (1.54e-1)" "unprognostic (4.84e-3)" "unprognostic (2.79e-1)" "unprognostic (9.65e-3)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.75e-2)" "unprognostic (2.67e-2)" "unprognostic (5.44e-3)" "unprognostic (1.03e-2)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "prognostic favorable (4.11e-5)" 23.4 12.5 7.3 10.3 10.6 44.2 19.5 5.4 11.4 28.5 14.4 18.9 16.4 7.5 31.8 16.1 12.1 22.2 19.1 9.0 8.6 6.1 13.1 3.5 19.0 19.4 12.9 8.8 22.3 10.5 9.8 6.1 84.0 7.4 20.1 9.7 20.2 16.2 20.9 20.6 16.7 15.7 18.0 7.0 23.5 14.8 15.2 12.2 8.8 39.1 10.9 15.7 19.0 33.7 4.9 1.4 14.2 2.3 3.2 8.4 1.5 2.0 4.1 1.7 2.0 17.3 4.6 4.5 1.4 3.4 3.5 7.6 11.5 2.1 9.2 7.4 2.2 2.4 5.1 8.1 2.5 3.0 3.3 8.4 6.2 4.3 2.1 2.5 4.2 6.1 7.4 3.3 1.8 1.4 1.7 8.0 2.0 17.8 10.9 1.3 7.7 0.1 20.8 4.9 4.9 3.7 2.1 7.9 33.8 3.7 24.6 8.6 3.7 1.8 18.8 9.5 14.8 3.5 10.4 2.3 1.6 4.0 1.2 3.6 10.1 4.4 4.9 1.0 12.3 5.5 8.5 2.3 11.1 8.4 2.2 7.3 4.9 5.3 5.9 1.4 4.9 5.9 5.4 14.2 3.2 2.0 0.7 3.2 1.5 7.3 10.6 5.4 11.4 8.6 6.1 12.9 8.8 7.4 12.2 20.8 36.3 30.2 28.3 87.0 7.3 74.2 35.7 21.4 18.2 21.0 0.0 113.9 8.3 14.9 36.7 33.1 32.6 0.0 16.2 65.2 75.2 27.4 35.7 1.0 27.7 11.1 80.9 34.4 42.6 12.5 35.6 21.9 75.9 26.2 35.2 15.3 8.1 32.3 58.0 18.8 6.6 135.8 92.6 59.7 17.5 73.4 294.6 88.3 34.8 26.9 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884331 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 191.1" "Cell type enhanced" "Detected in many" 16 "Peritubular cells: 649.2;Sertoli cells: 271.7;Smooth muscle cells: 829.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "basophil: 3.6;classical monocyte: 1.3;myeloid DC: 2.8;neutrophil: 4.5;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.8;granulocytes: 4.5;monocytes: 1.3" "Cell line enhanced" "Detected in many" "BJ: 36.4;BJ hTERT+: 55.1;fHDF/TERT166: 45.0;HBF TERT88: 29.0;hTERT-RPE1: 38.5;RPTEC TERT1: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 3000000 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 14.9 4.9 4.5 19.8 10.9 0.0 14.4 0.8 5.8 77.1 107.3 22.0 93.2 9.4 111.2 48.3 96.0 56.3 40.6 6.6 4.7 3.2 8.3 5.4 13.2 6.5 25.8 2.8 50.2 1.6 0.5 1.1 8.0 16.0 85.1 27.6 6.0 17.6 158.6 1.6 4.8 33.3 191.1 28.8 7.4 38.7 17.4 13.0 0.2 4.1 2.5 3.4 137.1 21.3 0.2 2.8 4.5 1.3 0.0 0.2 17.3 2.5 7.7 2.0 1.3 2.1 0.4 0.9 36.4 55.1 23.6 16.9 1.6 1.4 0.1 8.2 45.0 11.2 0.9 0.9 0.3 29.0 0.0 0.1 20.3 0.2 5.0 10.9 0.1 1.9 6.8 0.7 4.6 6.9 38.5 1.8 0.2 0.2 0.1 17.4 0.3 0.0 0.5 2.2 0.1 1.0 2.3 1.2 6.6 59.6 1.4 0.3 1.1 3.7 0.4 0.6 5.0 0.2 0.0 6.7 7.2 2.6 1.7 5.9 0.6 0.7 0.0 18.5 0.2 1.8 3.6 1.3 0.3 0.1 0.2 0.0 0.2 0.0 0.0 2.8 0.1 0.2 0.1 4.5 0.0 0.0 2.7 0.1 17.3 4.5 10.9 0.8 5.8 4.7 3.2 25.8 2.8 16.0 13.0 14.9 34.7 2.9 24.1 18.2 2.5 16.5 33.1 5.3 6.8 26.2 117.8 0.6 3.3 4.5 38.5 34.3 13.8 0.0 3.6 0.6 23.4 4.9 2.3 169.4 4.0 3.2 10.9 66.9 9.2 26.0 97.0 8.0 18.6 0.0 3.0 4.8 2.7 24.0 649.2 9.6 18.7 271.7 829.4 3.0 3.3 17.7 2.1 0.5 3.7 1.6 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 176.1" "Cell type enhanced" "Detected in single" 29 "Hofbauer cells: 1.4" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 5.3;RH-30: 13.5;RPMI-8226: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA059704: AB_2684108, HPA059890: AB_2684153" "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favorable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 1.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 176.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.1 18.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.8 0.0 0.0 0.5 0.1 0.0 0.4 0.1 0.3 0.3 0.6 0.4 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.2 0.7 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 1.7 1.0 0.7 0.2 5.3 0.1 0.8 0.7 0.4 0.7 0.0 0.4 0.8 13.5 10.9 0.1 0.1 0.7 0.6 3.4 0.1 0.0 0.1 0.1 0.1 2.7 0.3 1.0 0.6 3.0 0.1 1.0 0.2 0.2 3.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46703369-46790407 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 62.2;skeletal muscle: 20.8;tongue: 31.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 162.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 9.7;HEL: 29.1;K-562: 4.5;SK-BR-3: 6.1" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.8;hippocampal formation: 5.7" "Region enriched" "Detected in single" 5 "hippocampal formation: 5.2" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 0.7 0.0 1.7 0.1 0.0 0.1 0.2 0.2 0.0 3.8 0.0 0.0 0.1 3.4 2.0 0.8 0.1 62.2 1.5 1.4 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.5 0.2 6.6 1.0 0.0 0.0 1.3 0.0 20.8 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.3 0.0 0.1 31.1 1.1 0.1 0.0 1.2 0.9 2.6 0.7 1.2 0.7 0.2 0.0 0.1 0.1 0.1 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.7 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 1.6 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.0 6.1 0.2 2.9 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.7 0.6 0.6 0.4 0.4 0.7 0.5 0.5 0.3 1.2 0.7 0.7 2.6 1.2 0.5 0.9 0.3 0.2 0.7 1.7 0.1 0.2 1.5 1.4 0.1 0.4 6.6 0.3 0.0 3.5 0.0 0.7 0.0 0.5 162.4 0.0 16.0 6.8 0.0 2.0 1.4 0.0 0.0 7.4 0.0 0.0 0.0 0.2 0.4 1.4 0.6 1.1 0.0 0.4 0.0 0.0 0.6 0.0 3.2 0.6 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.9 0.2 0.0 0.2 0.0 0.0 0.2 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750966 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 23.6;tongue: 63.6" "Cell type enhanced" "Detected in some" 6 "Alveolar cells type 1: 3.0;Cholangiocytes: 2.5;Proximal tubular cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 6 "HEL: 12.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 0.5 0.3 0.3 0.3 0.4 0.4 0.8 1.4 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 1.0 0.2 0.3 1.0 0.5 0.5 2.6 0.3 0.5 0.3 0.4 0.3 0.3 1.1 0.7 0.7 0.4 0.4 0.4 0.1 0.4 2.4 0.4 23.6 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.0 63.6 1.5 0.5 0.3 0.1 0.8 0.3 0.3 0.9 1.4 0.1 0.3 0.2 0.6 1.2 1.0 1.2 0.6 0.7 1.6 0.5 0.4 0.5 1.1 1.1 1.6 0.8 0.2 1.9 0.2 0.5 0.7 0.2 0.6 12.7 0.6 0.1 0.3 0.3 0.6 1.5 0.5 0.1 1.2 0.6 0.5 0.2 0.1 0.1 0.3 0.5 0.1 1.4 0.2 0.4 0.0 0.9 0.0 0.0 0.9 0.3 1.0 0.6 0.3 0.2 0.5 1.1 0.4 0.8 0.7 0.5 0.1 0.2 0.4 0.4 0.2 0.1 0.2 0.3 1.3 0.1 0.1 0.1 0.5 0.0 0.3 0.1 0.2 1.4 0.2 0.1 0.6 0.1 0.3 0.9 0.3 0.8 0.1 0.1 0.3 0.4 1.4 0.7 0.5 0.5 0.4 0.3 0.4 0.3 3.0 0.6 0.0 0.1 0.1 0.8 1.2 2.5 0.0 1.2 0.0 0.0 0.3 0.0 0.1 0.4 0.5 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.2 1.6 1.2 0.0 0.3 0.0 0.3 1.0 0.0 1.8 0.0 0.2 0.0 0.0 1.4 2.9 0.2 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.1 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934071-26212536 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 8.1;testis: 12.5" "Cell type enhanced" "Detected in some" 23 "Early spermatids: 127.9;Late spermatids: 34.5;Muller glia cells: 68.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 5.0;cerebral cortex: 1.9;hypothalamus: 1.3;pons and medulla: 5.4" "Cell type enriched" "Detected in single" 12 "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 12 "B-cells: 1.1" "Cell line enhanced" "Detected in some" "AF22: 2.3;CAPAN-2: 2.2;HEK 293: 2.7;SCLC-21H: 2.5;U-2 OS: 4.4;U-698: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.8 0.7 0.4 0.3 5.0 0.5 1.5 0.3 1.9 2.1 0.6 0.1 0.7 0.4 0.3 3.2 0.9 1.1 0.3 0.3 0.5 1.3 0.9 0.2 1.0 0.3 0.2 0.0 0.5 2.1 0.2 8.1 0.2 5.4 0.5 1.1 3.8 0.2 0.6 0.3 2.2 0.6 1.0 0.4 0.3 0.9 12.5 0.8 0.0 1.3 1.4 0.9 0.5 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 1.5 0.0 0.0 1.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.0 0.3 1.9 0.5 1.3 0.2 0.0 5.4 0.8 0.0 0.3 0.0 0.3 1.5 0.9 0.6 0.0 0.0 4.5 0.0 0.0 0.0 1.7 0.5 127.9 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1.7 0.0 0.0 34.5 1.1 0.0 0.0 0.0 0.2 68.5 0.3 0.0 1.1 1.4 3.4 0.0 0.0 20.0 5.8 0.9 0.0 0.0 0.0 0.1 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.0;parathyroid gland: 12.6;retina: 21.6" "Cell type enhanced" "Detected in some" 20 "Cone photoreceptor cells: 80.5;Early spermatids: 23.6;Late spermatids: 18.5;Rod photoreceptor cells: 57.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "gdT-cell: 1.4;naive CD8 T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.4" "Group enriched" "Detected in some" 10 "HDLM-2: 11.3;HEL: 10.4;RT4: 11.7" "Region enriched" "Detected in single" 5 "basal ganglia: 4.7" "Not detected" "Not detected" HPA045483 Approved NA NA "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.2 0.2 0.3 0.0 0.3 0.0 0.2 0.2 0.3 0.6 0.2 0.0 4.6 0.0 0.3 20.0 0.3 0.5 0.0 0.3 0.3 0.5 8.5 0.2 0.3 0.5 0.3 0.3 0.4 2.2 12.6 1.0 0.0 0.3 0.3 0.0 21.6 1.4 1.1 0.2 0.5 0.2 0.5 0.2 0.3 0.2 4.2 0.0 0.0 2.2 0.0 0.8 4.4 0.3 0.1 0.3 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.3 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.3 0.3 0.5 0.3 0.3 0.3 0.0 0.0 0.3 0.0 0.3 0.6 2.9 0.4 0.0 0.0 0.0 3.5 80.5 0.0 11.6 0.3 23.6 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.3 18.5 0.3 0.2 0.0 0.0 0.2 1.6 0.1 0.0 0.4 0.1 57.8 0.0 0.1 0.9 0.2 0.4 0.1 0.0 0.0 0.1 NAGPA "APAA, UCE" ENSG00000103174 "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase" Q9UK23 16 5024844-5034141 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064055 Approved NA NA 3600000 "HPA064055: AB_2685183" "unprognostic (9.93e-2)" "unprognostic (1.61e-2)" "unprognostic (2.08e-2)" "unprognostic (2.21e-2)" "unprognostic (7.12e-3)" "unprognostic (3.30e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.05e-2)" "unprognostic (2.98e-2)" "unprognostic (1.35e-1)" "unprognostic (9.51e-3)" "unprognostic (9.41e-2)" "prognostic unfavorable (2.67e-5)" "unprognostic (1.26e-1)" "unprognostic (6.09e-2)" "unprognostic (7.47e-2)" "unprognostic (1.02e-1)" 8.3 6.3 9.9 9.0 20.1 8.7 4.7 4.7 25.0 6.8 8.5 4.6 5.8 11.4 6.2 4.7 6.1 4.8 5.6 5.0 15.3 5.3 7.2 7.6 7.6 9.1 5.0 9.5 4.2 7.3 7.6 4.9 6.8 6.6 4.9 5.1 4.0 6.0 6.2 6.7 8.5 9.2 5.5 4.4 10.9 12.4 2.7 5.5 4.3 5.1 2.6 5.6 6.0 4.4 9.5 26.5 5.1 20.9 5.1 9.9 9.7 1.5 6.0 1.0 6.5 2.6 3.4 6.8 4.5 8.0 5.9 7.4 5.0 12.5 0.6 5.7 6.1 10.2 4.6 2.7 5.0 1.8 7.3 8.4 2.2 3.9 32.2 8.3 5.3 9.5 5.1 5.2 3.9 1.7 7.4 9.1 5.6 6.9 8.9 3.6 6.8 2.4 14.4 3.2 3.8 6.4 6.5 2.4 11.8 3.8 2.4 2.6 3.5 3.6 8.9 9.1 1.0 6.1 6.6 6.7 6.5 4.7 15.1 3.3 4.9 3.8 1.4 3.0 8.2 5.4 1.2 20.9 5.1 9.9 18.2 7.9 9.5 9.8 8.8 26.5 8.3 8.1 7.4 0.6 5.1 11.7 6.8 8.7 9.7 9.9 20.1 4.7 25.0 15.3 5.3 5.0 9.5 6.6 5.5 0.0 2.4 13.7 4.8 2.6 13.3 1.5 7.6 4.0 3.4 5.2 29.5 11.3 1.7 10.2 0.2 6.7 17.1 0.0 7.5 12.5 3.2 3.7 1.1 7.3 25.0 15.9 1.2 8.6 17.2 0.9 7.5 19.1 3.3 25.2 9.9 5.4 8.5 14.4 6.0 7.4 12.5 0.0 3.1 4.4 8.1 2.0 7.9 13.8 10.6 2.1 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 23.4" "Cell type enhanced" "Detected in many" 7 "Ciliated cells: 34.8;Paneth cells: 25.9" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB017782, HPA043704" Approved NA NA "CAB017782: , HPA043704: AB_2678625" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.7 3.2 1.5 8.5 1.5 1.9 7.9 1.3 1.5 5.4 15.6 1.0 5.1 9.3 4.4 13.0 4.8 3.5 5.9 2.9 1.7 1.0 8.6 14.3 6.2 6.6 2.5 1.0 3.3 4.2 1.1 4.6 6.0 3.1 7.4 10.3 4.5 3.6 5.4 2.0 1.6 23.4 2.6 2.3 9.8 4.8 4.1 0.5 10.8 2.6 4.3 6.2 3.1 3.0 6.3 8.1 12.3 7.1 8.6 8.5 3.9 18.5 2.3 2.1 2.8 5.6 5.6 4.5 6.8 7.1 7.6 8.7 3.1 4.0 9.0 5.4 4.3 7.0 2.9 3.8 4.4 7.7 8.4 2.0 6.1 2.6 2.3 5.4 2.7 8.4 4.6 5.7 5.1 0.4 1.9 6.6 8.0 5.3 2.5 8.3 3.3 8.0 8.6 2.0 14.6 2.9 4.0 2.0 3.8 8.0 10.7 1.1 1.4 0.3 8.0 4.6 4.7 6.5 8.1 6.6 4.5 2.7 6.9 1.1 1.7 3.2 7.8 4.0 6.2 2.0 5.3 6.4 12.3 4.8 7.1 3.5 6.3 5.0 4.8 8.1 5.4 4.8 5.8 11.2 8.6 6.8 4.7 8.5 3.9 1.5 1.5 1.3 1.5 1.7 1.0 2.5 1.0 3.1 0.5 0.0 2.2 3.0 0.6 0.3 0.0 1.1 0.0 34.8 5.7 5.2 0.0 5.2 1.7 5.3 3.9 1.5 12.6 0.0 6.1 6.9 2.1 1.8 2.3 11.9 6.4 0.0 3.5 2.5 8.4 1.6 3.7 4.6 3.3 2.8 8.8 2.4 4.3 25.9 5.3 10.6 0.0 0.0 4.1 1.4 0.5 0.5 9.2 4.9 7.8 1.2 NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391245-18401218 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "intestine: 28.4;liver: 75.5" "Cell type enhanced" "Detected in some" 25 "Enterocytes: 16.0;Hepatocytes: 52.3;Paneth cells: 10.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.8;RT4: 4.2;SCLC-21H: 5.8;SK-BR-3: 3.6" HPA043704 Uncertain NA NA "HPA043704: AB_2678625" "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" 0.2 0.1 0.2 2.3 0.3 0.0 0.3 0.1 0.2 0.3 14.0 0.1 0.1 13.0 0.4 0.4 0.1 0.2 0.3 0.4 0.1 0.1 0.6 75.5 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.3 5.1 0.1 0.1 0.1 0.1 0.1 28.4 0.4 0.2 0.6 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.3 0.0 1.8 0.0 0.2 0.0 1.4 0.0 0.0 0.3 0.3 0.1 0.5 0.1 0.5 0.1 0.7 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.9 0.0 0.0 0.9 0.0 2.8 4.2 5.8 0.1 0.1 3.6 0.0 0.5 1.0 0.6 1.5 1.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.1 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 5.0 0.0 0.1 0.0 16.0 0.0 0.0 0.8 0.0 0.1 0.0 52.3 0.2 0.0 0.0 0.6 0.6 0.0 0.6 0.0 0.0 0.0 7.5 0.0 0.1 10.1 2.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 4.2 0.0 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 41.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 9.8 10.0 15.3 7.3 18.0 8.9 10.5 15.9 17.1 13.7 8.9 13.5 4.9 12.5 13.0 11.5 10.8 10.0 8.3 8.8 20.8 12.2 11.9 8.8 9.4 8.2 10.8 9.9 17.2 10.3 23.9 16.0 10.1 14.2 9.6 10.1 19.9 10.6 13.0 42.5 9.3 10.9 11.6 9.7 9.6 7.6 11.4 10.7 8.5 7.0 12.2 9.3 9.7 10.8 2.5 5.5 14.2 3.5 3.4 4.1 1.8 6.7 5.0 8.9 4.6 9.8 9.0 13.6 3.6 7.3 4.6 4.1 4.7 2.9 4.9 1.5 6.6 8.8 1.6 5.3 3.1 5.0 23.3 7.7 17.6 2.0 1.9 6.2 8.0 14.7 14.3 4.7 4.4 3.6 5.7 4.6 6.4 10.7 8.2 6.9 4.5 7.1 2.9 4.2 4.0 3.4 5.7 41.0 2.5 5.0 9.2 8.1 6.4 8.4 5.1 3.7 4.9 6.1 4.1 5.0 7.7 6.1 5.2 3.6 9.5 8.2 8.6 4.4 5.1 3.8 11.0 3.5 6.9 3.8 2.7 4.1 1.8 3.4 4.1 2.6 2.5 3.3 4.0 14.2 3.4 2.8 5.5 3.7 1.8 15.3 18.0 15.9 17.1 20.8 12.2 10.8 9.9 14.2 10.7 35.7 29.8 13.6 10.7 27.1 97.2 33.1 15.3 20.1 31.8 14.0 49.1 11.2 6.6 12.0 13.1 29.2 24.6 23.3 23.0 14.9 31.2 14.1 18.6 20.3 15.3 58.8 24.2 33.2 25.2 3.8 43.7 26.2 18.6 10.0 22.7 63.8 17.7 35.1 40.7 11.4 67.4 38.8 35.4 32.1 36.8 27.0 4.5 25.4 23.0 14.6 NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109762-70403805 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Nucleoplasm, Nuclear bodies" "HPA060243: AB_2684229" "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favorable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" 13.6 13.2 16.9 13.1 14.0 22.5 14.9 19.2 14.0 13.9 17.3 10.1 49.7 12.4 16.6 33.6 20.0 12.5 12.6 15.8 13.9 13.0 16.4 25.5 15.5 16.9 10.8 11.4 18.5 9.7 23.4 17.1 16.2 10.0 14.8 11.8 15.3 14.8 21.7 13.2 14.9 28.8 19.2 9.6 14.5 11.7 15.5 12.9 15.3 13.4 10.3 13.8 18.9 17.2 3.8 2.5 9.4 7.8 2.1 3.8 1.6 8.8 11.0 12.2 6.9 11.1 11.4 12.5 5.1 5.1 3.9 3.8 5.6 10.3 10.5 2.1 9.3 6.5 5.2 14.9 7.0 4.4 24.8 11.8 18.3 5.6 8.9 5.8 3.7 4.9 9.9 7.9 5.3 7.6 6.2 2.7 7.7 5.8 16.0 4.5 8.8 9.1 3.7 6.4 10.1 5.2 9.0 5.1 6.5 6.3 14.7 9.3 6.8 8.8 4.7 7.2 8.9 11.1 6.8 3.5 5.7 7.3 7.2 2.7 21.1 10.8 10.2 5.8 4.9 8.3 4.5 2.5 3.5 3.8 3.9 2.8 2.2 2.3 3.3 2.5 3.8 2.8 2.7 9.4 2.1 7.8 1.1 3.2 1.6 16.9 14.0 19.2 13.5 13.9 13.0 10.8 11.4 10.0 12.9 11.9 24.3 16.7 7.9 14.3 23.6 31.3 33.1 9.4 34.2 24.4 49.1 16.2 10.0 6.0 4.0 14.5 20.6 23.3 10.7 10.2 16.2 17.2 21.9 57.7 14.7 69.9 24.2 22.7 43.2 5.7 18.4 19.9 20.3 4.6 17.5 14.7 10.9 11.5 20.8 15.7 29.6 25.8 15.6 11.2 15.4 18.7 26.5 25.4 16.0 12.2 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501902-47656877 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 38.1;MCF7: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 20.1 8.9 6.6 34.0 7.4 11.1 15.7 11.9 9.9 12.3 10.1 8.1 9.0 6.7 15.5 8.8 16.7 12.0 8.6 11.5 6.7 4.8 9.1 9.3 17.4 25.8 7.9 4.7 13.3 10.7 13.5 13.5 54.7 7.9 9.7 9.0 10.8 13.5 10.0 32.5 15.0 17.1 11.3 9.5 30.8 11.4 9.2 7.2 17.6 13.5 10.5 33.3 15.1 17.7 13.0 6.7 6.0 7.3 2.7 4.0 3.5 5.9 19.2 5.4 7.3 12.8 15.0 38.1 5.7 8.6 9.8 5.2 9.2 6.5 20.5 3.8 9.8 13.8 14.4 4.2 7.0 7.5 10.8 2.2 2.8 5.4 12.7 7.6 2.2 15.3 6.8 20.2 9.3 10.8 7.9 6.9 3.4 6.3 4.8 5.4 63.9 3.2 3.8 1.9 4.5 7.4 6.1 3.8 8.8 5.4 13.8 1.0 1.9 14.4 17.9 6.1 6.5 8.3 5.6 12.0 5.8 5.1 7.0 2.5 13.2 12.0 21.1 6.8 2.2 3.9 3.4 5.2 4.0 3.5 7.3 3.2 13.0 3.2 3.1 6.7 10.0 3.7 4.0 6.0 2.7 7.0 5.5 4.0 3.5 6.6 7.4 11.9 9.9 6.7 4.8 7.9 4.7 7.9 7.2 11.9 21.3 77.0 14.2 30.7 16.1 22.0 20.4 22.7 17.0 14.0 7.9 56.2 5.0 11.0 9.0 39.0 7.8 0.0 16.8 23.2 22.6 21.3 8.1 18.4 20.1 12.7 14.3 66.9 49.4 3.6 23.0 45.5 32.1 22.6 11.4 9.7 15.9 14.0 25.8 5.1 22.4 19.4 26.8 22.7 17.8 45.2 74.6 22.4 11.7 56.9 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825649 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA004198: AB_1078228, HPA050211: AB_2681052" "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favorable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 13.7 13.4 14.7 12.8 23.0 15.8 17.7 31.9 17.3 14.9 16.9 28.5 17.5 16.4 16.7 16.3 17.1 14.9 14.2 11.8 16.2 11.7 13.6 10.8 13.2 10.8 18.7 12.6 15.5 15.8 35.1 17.7 18.1 14.4 13.1 18.8 14.4 16.4 18.4 17.6 18.4 21.2 19.8 21.8 11.2 14.6 22.6 22.6 16.9 17.7 9.7 13.2 16.6 14.6 2.7 3.1 6.5 2.1 2.1 2.7 1.3 14.3 8.6 19.5 11.7 10.7 12.0 12.7 7.0 9.0 12.7 10.2 21.9 10.1 10.2 7.8 12.5 15.5 17.6 17.3 11.8 14.5 5.1 7.8 23.9 9.5 12.9 11.8 13.3 17.7 9.0 21.9 11.9 14.8 8.8 11.9 11.8 12.1 14.1 10.4 9.3 21.2 8.4 4.0 12.1 12.5 14.2 23.5 9.1 9.3 9.6 16.3 11.1 12.8 31.2 12.0 9.4 13.1 10.8 11.6 20.6 12.6 15.2 11.6 16.2 13.5 11.8 13.6 7.9 9.1 3.0 1.7 6.5 2.7 1.6 2.6 2.7 2.5 2.3 3.1 2.1 2.3 1.5 4.4 2.1 2.1 2.8 1.4 1.3 14.7 23.0 31.9 17.3 16.2 11.7 18.7 12.6 14.4 22.6 23.8 13.6 9.7 8.2 15.0 26.7 16.7 22.9 16.0 9.1 15.7 27.5 9.8 5.0 11.3 21.4 11.1 16.8 23.3 10.7 10.0 11.1 13.7 5.8 11.4 9.4 31.8 10.4 13.5 12.9 13.4 16.7 10.1 10.1 9.0 18.4 10.0 12.8 8.6 12.7 8.1 27.6 25.8 13.2 22.1 23.7 18.2 13.3 11.7 16.2 13.9 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370" "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favorable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 19.6 21.2 25.4 24.0 30.8 27.0 25.0 41.8 31.5 24.0 30.6 19.6 18.6 33.2 29.0 19.5 25.0 20.5 21.9 17.8 22.4 17.8 25.6 33.8 20.1 19.5 25.1 19.1 25.9 24.3 39.9 39.8 19.8 21.6 20.8 29.7 17.1 20.9 29.1 43.0 23.8 36.9 29.7 26.4 23.7 29.8 22.1 26.4 38.8 25.3 15.7 23.8 29.6 27.0 43.4 29.9 78.2 24.8 30.4 35.5 19.7 20.4 34.2 24.4 20.3 20.1 15.3 12.2 15.1 17.1 16.6 15.1 18.3 9.4 21.5 10.7 26.3 12.4 15.6 30.0 18.3 24.7 28.6 22.2 21.4 29.6 21.4 19.7 13.4 25.6 15.7 19.2 25.7 30.1 14.2 23.0 30.4 18.6 8.9 16.3 13.3 23.6 8.6 12.1 36.0 9.3 23.6 24.8 10.0 17.2 23.2 8.3 13.9 24.9 10.9 11.8 65.5 10.5 15.3 20.0 17.1 10.1 12.5 20.8 6.1 7.1 12.5 16.3 16.0 14.6 78.2 24.8 52.2 31.3 19.5 25.9 40.7 35.5 34.1 17.5 43.4 34.7 34.8 48.5 30.4 24.0 29.9 31.7 19.7 25.4 30.8 41.8 31.5 22.4 17.8 25.1 19.1 21.6 26.4 74.5 98.7 86.4 91.4 60.2 144.1 78.9 66.2 61.6 72.8 50.6 149.2 79.2 29.9 80.2 53.7 68.9 164.0 93.5 85.1 85.7 74.0 70.9 83.3 105.0 67.5 122.3 84.4 59.5 70.8 35.4 94.0 84.8 35.4 184.0 101.0 81.4 89.5 133.5 114.2 37.3 152.7 90.5 89.5 82.3 75.1 59.6 73.2 110.7 125.6 110.0 NCOR2 "CTG26, SMRT, SMRTE, TNRC14, TRAC-1" ENSG00000196498 "Nuclear receptor corepressor 2" Q9Y618 12 124324415-124567589 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001928 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA001928: AB_1079454" "unprognostic (9.51e-3)" "unprognostic (7.37e-3)" "unprognostic (4.66e-2)" "unprognostic (2.55e-3)" "unprognostic (2.14e-1)" "unprognostic (7.37e-2)" "unprognostic (3.19e-2)" "unprognostic (8.86e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-3)" "unprognostic (6.42e-3)" "unprognostic (1.96e-1)" "unprognostic (9.86e-2)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (7.56e-2)" "unprognostic (8.90e-2)" 24.0 22.0 21.3 21.3 19.0 16.8 18.3 33.8 33.5 24.5 17.2 24.3 17.7 16.4 21.3 19.0 15.7 16.3 21.5 18.2 22.0 14.8 16.0 11.2 23.4 11.9 19.0 15.6 28.6 30.0 13.8 39.5 13.2 28.3 21.3 7.6 32.7 29.2 24.5 62.4 22.8 22.2 17.4 12.2 17.4 24.0 10.8 22.0 9.3 16.7 25.0 7.6 16.3 14.7 0.6 1.7 8.1 4.0 0.2 1.9 0.4 19.7 37.2 10.6 10.1 6.2 8.4 31.8 20.5 10.2 12.0 5.3 19.7 14.6 20.0 15.2 16.7 10.7 18.8 4.2 21.8 4.9 21.1 8.2 16.1 35.1 12.0 12.4 12.1 20.5 13.5 8.2 14.9 8.9 18.4 11.4 9.2 20.6 6.0 10.7 17.0 43.4 14.0 14.8 7.5 36.2 14.1 17.7 10.1 5.7 23.1 28.1 20.5 25.2 21.3 12.9 8.3 17.3 15.3 54.6 27.9 48.3 27.5 43.4 11.5 11.5 12.2 15.9 9.0 26.1 8.1 0.7 1.6 1.9 0.4 0.5 0.6 0.5 1.5 0.3 0.4 0.6 0.5 1.6 0.2 4.0 1.7 0.0 0.4 21.3 19.0 33.8 28.4 22.0 14.8 19.0 15.6 28.3 22.0 107.2 54.1 4.5 21.5 29.7 63.3 27.7 20.4 18.7 56.9 17.4 37.3 6.7 3.3 19.2 1.6 21.0 23.6 0.0 24.0 33.5 32.5 20.3 39.5 16.3 25.4 114.4 18.0 14.7 40.3 4.8 57.5 32.4 15.1 18.0 18.7 30.6 26.9 17.3 61.2 7.0 57.9 6.5 30.6 1.7 10.3 21.3 10.5 13.1 20.4 17.9 NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase" P46934 15 55826922-55993746 "Enzymes, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.7" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 86.4;Alveolar cells type 2: 87.7;Ciliated cells: 135.1;Club cells: 79.6;granulocytes: 67.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, CAB072833" Approved Approved Cytosol NA NA Cytosol "CAB001991: , CAB072833: , HPA039883: AB_10795683" "unprognostic (1.18e-1)" "unprognostic (2.10e-2)" "unprognostic (5.66e-3)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.18e-3)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (6.38e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-2)" 14.1 4.1 2.5 3.1 3.3 4.5 8.7 1.5 2.7 9.9 9.4 2.8 3.4 3.4 10.1 4.1 8.2 3.8 4.5 4.1 2.9 2.4 8.6 21.5 7.2 2.1 3.5 1.3 6.6 2.8 6.5 6.7 20.1 3.5 8.4 3.4 5.4 4.0 6.4 57.7 7.1 15.2 10.9 6.0 5.9 4.4 2.6 3.1 9.4 5.7 9.0 3.3 11.9 8.9 0.1 1.6 1.2 2.8 1.2 2.9 0.9 7.3 11.5 3.1 3.0 4.1 6.8 5.1 14.1 22.3 10.5 10.5 5.1 2.2 1.8 3.7 5.4 25.5 12.2 3.4 9.3 17.2 4.1 2.1 9.1 2.7 2.6 21.9 4.0 0.9 11.6 23.1 12.5 21.1 5.1 8.6 5.4 3.9 0.0 30.6 3.8 5.3 0.0 0.8 3.9 1.7 3.9 24.8 1.0 4.3 14.6 0.3 2.0 6.3 4.5 5.6 5.9 5.6 3.0 29.6 23.3 7.7 4.9 22.9 1.2 2.7 4.8 15.7 8.6 5.5 0.6 1.0 0.0 1.3 2.8 2.9 0.1 1.5 1.2 0.8 0.0 1.4 1.6 1.2 1.2 1.9 1.6 1.3 0.9 2.5 3.3 1.5 2.7 2.9 2.4 3.5 1.3 3.5 3.1 86.4 87.7 2.0 3.3 10.8 0.3 4.8 7.6 135.1 79.6 0.0 21.6 16.5 1.7 3.2 1.3 16.8 6.9 0.0 4.8 6.4 6.3 3.4 67.4 17.9 4.0 0.0 0.0 15.4 1.8 1.0 5.2 3.8 1.7 0.0 4.2 8.4 3.3 0.0 6.7 10.8 6.0 0.0 8.2 1.2 5.9 9.2 11.6 2.2 2.9 1.6 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase" Q96PU5 18 58044367-58401540 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Alveolar cells type 1: 235.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 4 "granulocytes: 4.7;T-cells: 8.1" "Cell line enhanced" "Detected in many" "Hep G2: 51.3;SK-MEL-30: 40.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved NA NA "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 5.9 6.8 9.1 5.4 38.8 13.2 15.8 21.4 24.7 5.0 22.6 3.2 18.2 11.1 3.6 6.1 7.0 6.0 7.6 12.7 9.8 7.1 29.9 10.1 26.9 2.5 7.2 14.9 3.0 33.2 9.2 16.5 13.0 4.1 30.6 25.2 12.2 16.5 23.2 38.3 5.9 26.8 8.2 3.2 3.1 26.0 4.6 8.8 0.8 9.1 5.5 5.1 14.9 9.3 1.4 0.4 4.7 0.7 0.9 8.1 0.5 18.8 6.8 4.0 6.0 1.4 0.5 13.9 5.4 24.2 13.7 21.0 7.9 10.2 4.0 16.4 2.1 14.4 13.7 5.3 23.6 28.4 9.4 4.7 2.8 4.2 51.3 0.7 0.1 1.7 3.6 15.4 18.5 22.4 10.8 1.0 3.6 4.9 1.8 5.6 4.6 0.2 0.2 3.4 7.0 10.4 3.9 5.4 4.6 13.6 24.7 5.0 1.4 4.4 1.4 40.0 8.1 8.0 1.6 8.1 37.0 11.2 2.1 22.8 2.3 4.0 2.5 7.5 2.9 3.0 4.7 0.6 1.7 0.4 0.7 1.0 1.4 1.3 0.3 0.3 0.6 0.8 0.6 0.3 0.9 0.1 0.4 8.1 0.5 9.1 38.8 21.4 24.7 9.8 7.1 7.2 14.9 4.1 8.8 235.2 122.6 2.7 142.5 100.2 4.9 50.9 56.0 92.3 166.1 59.3 163.0 7.6 41.4 32.0 18.9 9.0 128.1 116.8 42.3 4.2 11.0 173.0 3.5 32.7 6.3 58.8 43.5 9.8 5.4 5.6 3.1 11.5 13.5 8.2 189.6 31.3 41.1 77.0 16.6 59.9 7.5 0.0 5.3 0.2 3.0 46.3 66.9 4.6 64.4 150.4 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392857-169612629 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Ciliated cells: 85.6;Early spermatids: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 9.6 10.5 13.5 9.2 15.8 6.0 8.7 20.7 14.5 13.6 8.4 12.5 7.1 5.4 12.4 9.1 7.9 15.7 10.2 11.4 13.7 13.2 10.2 6.9 7.7 8.0 15.9 11.3 16.3 6.6 15.3 16.5 7.2 16.0 11.6 7.7 8.9 6.4 10.6 7.1 4.7 5.7 11.1 18.2 8.0 8.1 18.3 14.8 14.7 13.3 6.4 7.4 10.0 8.2 4.5 3.3 6.7 3.3 2.2 5.3 1.3 4.2 1.8 7.8 8.4 12.1 13.5 2.5 8.9 8.0 7.2 6.8 2.4 5.0 11.3 1.7 7.8 6.9 1.4 7.3 7.6 8.2 12.4 5.0 7.6 7.7 2.9 7.1 7.6 6.1 10.8 4.3 7.3 12.8 14.7 7.0 10.9 13.4 21.5 9.2 2.7 9.8 3.4 2.5 2.7 4.5 6.1 5.1 3.6 7.6 5.0 8.5 9.7 6.5 3.2 6.0 6.2 4.0 3.4 8.4 4.6 4.2 4.7 6.0 8.7 13.3 8.6 7.6 3.8 8.0 6.7 2.1 1.8 4.4 3.3 4.8 4.4 3.4 2.7 1.5 4.5 5.1 5.3 1.1 2.2 1.6 3.3 3.2 1.3 13.5 15.8 20.7 12.9 13.7 13.2 15.9 11.3 16.0 14.8 11.9 13.1 13.3 12.5 8.5 20.5 31.9 0.0 85.6 22.7 17.4 27.5 17.5 14.9 8.5 83.6 9.0 5.4 23.3 5.5 6.7 16.2 7.0 17.4 6.6 9.1 17.5 6.9 8.6 6.9 39.7 21.9 8.9 5.0 2.8 5.0 23.4 6.9 4.2 29.7 8.1 24.4 12.9 18.6 59.1 27.4 5.5 24.7 8.6 6.8 9.5 NEK11 FLJ23495 ENSG00000114670 "NIMA related kinase 11" Q8NG66 3 131026850-131350465 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.9" "Cell type enhanced" "Detected in many" 14 "Ciliated cells: 148.5;Early spermatids: 122.2;Late spermatids: 80.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016908 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA016908: AB_1854364" "unprognostic (9.15e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (4.85e-3)" "unprognostic (2.48e-5)" "unprognostic (5.38e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "prognostic favorable (5.92e-6)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" 3.9 5.8 9.3 2.7 11.1 0.5 8.7 2.7 7.6 7.3 2.8 11.2 8.4 2.0 6.5 16.0 3.2 26.9 6.0 2.9 9.1 10.0 8.2 1.1 5.5 1.7 7.8 5.4 8.7 2.8 5.0 9.3 4.6 17.3 4.0 3.3 3.0 3.8 6.7 1.7 2.8 2.6 4.3 7.3 1.8 2.3 17.8 5.5 0.2 12.3 2.5 1.7 4.2 3.0 0.9 1.0 1.1 1.3 0.3 2.9 0.3 5.9 2.4 1.8 5.2 7.0 10.5 1.0 2.9 5.5 4.5 3.4 2.2 8.3 0.3 2.1 5.2 4.3 3.3 0.5 5.1 6.3 0.6 0.7 0.8 0.4 1.0 2.3 0.6 1.5 4.4 8.5 4.8 2.2 4.8 0.9 2.6 0.2 0.9 7.5 4.2 0.1 0.5 0.5 0.9 2.3 0.0 0.2 0.1 10.3 2.3 2.2 2.5 1.4 0.1 2.0 0.8 4.9 0.1 0.9 4.7 2.3 3.6 1.4 1.4 2.3 0.1 3.2 0.2 0.8 0.0 0.3 1.1 0.6 1.3 1.2 0.9 2.9 2.6 0.5 0.6 1.0 0.8 0.9 0.3 0.9 1.0 1.5 0.3 9.3 11.1 2.7 7.6 9.1 10.0 7.8 5.4 17.3 5.5 14.9 2.7 0.0 3.4 3.8 2.7 1.1 2.5 148.5 29.6 1.8 5.9 0.5 5.0 4.7 122.2 2.4 1.7 0.0 2.2 1.0 5.4 1.4 0.0 0.0 1.8 0.0 2.4 2.5 0.0 80.8 6.4 1.4 0.0 1.0 2.7 5.7 2.9 3.7 5.6 8.4 6.9 6.5 2.2 30.5 4.9 1.8 1.4 0.0 1.7 1.8 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0;testis: 41.0" "Cell type enhanced" "Detected in many" 22 "Early spermatids: 44.4;Erythroid cells: 93.5;Spermatocytes: 191.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.2" "Not detected" "Not detected" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 1.1 0.7 0.6 6.7 0.5 7.4 1.3 0.3 0.9 0.9 2.5 0.3 0.3 3.4 0.3 1.2 4.2 0.7 1.4 0.9 1.0 0.3 0.6 0.6 1.0 3.9 0.3 0.3 0.6 0.3 0.0 0.3 1.2 0.4 0.9 3.6 0.4 1.0 0.3 0.3 1.8 3.0 0.6 0.6 1.6 1.1 41.0 0.4 14.0 0.3 1.5 4.8 0.6 1.6 1.8 0.9 2.7 0.5 3.9 4.3 0.9 30.7 22.2 17.0 12.2 1.0 1.7 18.8 11.9 11.2 21.0 18.1 11.8 30.3 16.4 5.7 9.2 13.3 16.5 14.8 8.9 26.5 25.0 12.3 7.8 19.4 15.9 0.1 15.4 10.7 0.5 1.1 16.1 17.4 5.1 13.5 16.7 21.4 28.8 21.0 8.6 16.8 10.4 16.1 19.9 11.4 16.6 26.1 24.9 7.3 8.8 15.4 17.1 17.2 19.2 14.9 15.2 29.6 9.2 7.0 10.5 20.8 20.6 31.9 11.9 22.0 21.7 9.1 11.9 17.4 2.7 0.5 0.4 0.5 0.3 0.2 1.5 0.6 0.3 0.1 1.8 1.1 0.7 2.4 3.9 0.4 0.9 4.3 0.9 0.6 0.5 0.3 0.9 1.0 0.3 0.3 0.3 0.4 0.4 0.0 0.3 0.8 0.5 2.6 0.7 0.4 0.0 2.7 3.4 0.0 0.0 0.9 0.0 0.1 44.4 0.1 1.1 93.5 0.2 11.4 0.2 0.3 0.0 0.0 4.7 3.2 0.0 2.5 2.8 28.5 2.3 1.1 0.0 0.0 1.2 0.8 0.0 0.8 0.7 0.0 1.9 6.5 0.0 191.1 25.4 1.5 1.1 0.7 2.3 0.9 NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatocytes: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved Microtubules NA NA Microtubules "HPA019062: AB_2670037, HPA043230: AB_2678374" "unprognostic (8.97e-2)" "unprognostic (2.54e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (4.30e-3)" "unprognostic (1.16e-3)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (4.15e-2)" "unprognostic (5.34e-2)" 7.7 2.8 7.1 5.4 12.9 7.1 7.3 3.2 7.1 7.0 13.8 20.4 3.1 7.8 9.1 5.8 3.9 6.0 6.4 5.0 8.7 5.2 6.1 5.7 7.2 4.2 14.0 9.5 7.9 6.4 2.2 3.7 14.8 11.3 5.4 15.0 6.8 5.2 5.0 4.1 5.4 11.7 7.3 9.6 3.9 4.6 14.7 13.3 2.4 5.0 2.7 4.3 6.5 6.0 4.4 7.8 5.9 7.7 2.0 3.5 1.6 0.2 1.4 13.2 7.5 4.2 6.6 0.2 4.2 4.3 5.1 5.7 5.1 7.3 0.0 0.2 5.3 4.2 0.9 0.2 3.2 3.1 8.7 6.9 1.0 1.4 13.7 5.4 12.7 6.8 4.8 5.9 2.6 12.2 3.7 7.8 0.6 1.8 4.4 5.2 3.6 0.6 15.3 12.9 2.7 0.3 0.3 1.1 4.8 7.3 1.3 1.3 9.1 1.9 4.0 8.9 13.0 1.7 16.3 6.7 0.7 4.3 4.0 4.5 4.7 1.6 8.8 1.1 5.0 7.2 5.9 7.7 5.3 2.1 6.6 1.3 4.4 2.5 1.3 7.8 2.5 1.7 0.6 0.5 2.0 1.5 6.9 3.5 1.6 7.1 12.9 3.2 7.1 8.7 5.2 14.0 9.5 11.3 13.3 6.0 6.2 1.9 3.8 2.5 2.2 6.1 7.6 8.1 7.9 7.0 0.0 10.1 11.6 5.4 6.3 21.2 18.6 0.0 15.1 12.1 7.0 4.2 9.3 6.2 15.3 3.2 5.8 20.9 9.9 2.7 6.6 7.9 11.8 34.3 14.6 3.7 11.3 14.0 6.3 5.0 5.8 0.0 7.6 40.9 27.9 3.0 4.0 1.3 17.2 4.8 NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708449-52770949 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.7" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol NA NA Cytosol "HPA015750: AB_1854367, HPA058543: AB_2732623" "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.69e-5)" "unprognostic (9.65e-3)" "unprognostic (3.42e-1)" "unprognostic (6.64e-2)" "unprognostic (8.75e-3)" "unprognostic (2.27e-1)" "unprognostic (7.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-3)" "unprognostic (5.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" 7.2 10.7 15.5 9.1 15.7 7.3 11.0 20.2 16.1 10.6 8.4 10.6 9.6 7.6 10.3 10.7 8.1 15.8 7.5 7.4 12.5 14.2 11.6 12.4 7.7 8.8 12.7 8.6 15.8 10.2 13.4 17.6 8.7 11.9 9.4 9.7 9.1 8.5 11.3 10.8 5.3 6.6 9.5 10.7 7.9 11.0 47.7 12.4 11.1 15.5 5.0 10.4 9.3 10.7 5.1 6.4 12.4 11.8 4.6 5.2 5.5 12.9 10.1 13.9 10.9 12.7 9.2 15.1 9.2 12.5 17.3 17.5 8.8 9.7 13.3 4.3 9.0 19.1 6.1 16.9 10.9 23.2 13.3 7.1 10.4 12.3 11.2 7.9 25.4 10.5 5.6 10.1 22.1 14.8 9.2 6.4 11.7 12.9 10.9 10.9 11.1 13.7 9.3 12.0 13.7 10.0 12.0 12.1 9.8 9.8 18.7 10.3 6.1 19.4 11.9 9.1 11.2 11.1 15.3 5.9 11.6 11.8 18.5 17.0 12.2 17.7 13.1 13.3 12.0 12.5 12.4 11.8 5.8 4.6 7.3 5.2 3.6 4.0 4.8 6.4 5.1 4.9 4.2 1.8 4.6 4.8 3.2 3.1 5.5 15.5 15.7 20.2 16.1 12.5 14.2 12.7 8.6 11.9 12.4 11.9 5.1 9.5 4.6 3.7 12.7 3.5 0.0 21.4 15.9 5.2 11.8 6.1 8.3 6.4 16.2 5.3 5.1 0.0 8.4 6.8 4.6 6.5 7.0 13.4 7.2 6.4 4.6 4.9 14.9 16.1 13.6 7.0 1.7 5.4 9.6 16.2 7.8 0.0 11.7 14.6 17.4 6.5 5.9 58.3 31.9 3.6 5.6 5.3 8.2 4.1 NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129078 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 11.8;fallopian tube: 12.7;testis: 15.7" "Cell type enriched" "Detected in many" 4 "Ciliated cells: 172.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "JURKAT: 3.5;OE19: 6.4;T-47d: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035565, HPA041399" Enhanced NA NA "HPA035565: AB_10672095, HPA041399: AB_2677453" "unprognostic (4.14e-2)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-2)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (6.50e-2)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (2.06e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (1.19e-3)" "unprognostic (9.44e-3)" 0.6 0.3 3.2 1.4 3.2 0.7 0.9 0.4 2.6 0.9 0.4 5.4 0.3 0.5 2.5 3.0 0.4 12.7 0.5 1.3 3.2 1.6 0.9 0.3 4.9 0.5 0.7 1.3 2.8 0.5 0.9 5.3 0.8 11.8 1.5 0.4 0.3 0.5 0.3 0.6 0.5 0.4 0.5 0.9 0.4 0.3 15.7 2.1 0.0 0.7 0.0 0.3 0.4 0.4 0.9 1.1 2.5 0.5 0.6 0.4 0.0 0.4 0.5 0.3 1.7 0.2 1.1 2.2 0.0 0.0 0.0 0.2 0.1 1.1 0.5 0.2 0.0 0.1 0.4 0.2 0.4 0.0 0.1 0.3 0.6 0.6 0.4 0.3 1.1 1.3 0.3 0.8 0.1 0.6 0.4 0.2 3.5 1.2 0.8 0.0 1.3 0.6 0.8 0.5 6.4 0.6 0.2 0.1 0.0 1.9 0.5 0.6 0.8 0.4 0.0 1.0 1.0 3.3 1.3 0.4 0.2 0.2 0.2 0.2 0.3 0.2 0.3 0.1 0.2 0.3 2.5 0.5 0.1 0.3 0.3 0.4 0.5 0.2 0.2 0.1 0.9 0.3 0.3 0.9 0.6 0.1 1.1 0.2 0.0 3.2 3.2 0.4 2.6 3.2 1.6 0.7 1.3 11.8 2.1 0.0 1.3 2.2 1.7 0.0 8.0 1.6 2.5 172.6 21.6 7.0 13.7 2.2 1.7 1.1 43.0 1.7 0.8 0.0 2.6 1.5 1.1 3.2 2.3 0.9 1.0 12.7 1.7 0.6 0.0 24.4 2.0 0.8 0.0 1.0 0.3 2.4 0.7 0.0 2.1 1.0 11.4 6.5 0.3 21.1 12.0 0.1 1.6 0.0 1.0 0.8 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Extravillous trophoblasts: 103.8;Hofbauer cells: 99.7;monocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 14.8 5.3 26.1 22.2 29.1 12.8 18.8 7.2 21.2 20.5 15.6 13.4 4.3 12.5 9.2 7.5 6.8 8.5 18.4 7.0 17.1 16.6 12.9 51.9 17.0 18.1 19.4 13.3 11.2 20.5 1.6 6.4 21.4 14.7 14.8 16.6 18.5 16.9 13.2 5.5 5.1 18.2 23.4 13.0 11.3 19.0 5.8 12.9 4.0 6.3 1.9 22.0 17.7 10.1 21.9 11.5 29.0 18.8 8.3 3.8 7.6 7.4 12.3 11.9 4.6 22.5 29.4 14.8 9.4 15.1 14.6 12.2 11.6 14.0 9.1 15.1 18.1 33.4 1.4 6.1 27.3 9.9 10.0 5.4 24.9 10.4 20.4 26.9 4.5 62.6 39.1 4.4 13.8 14.3 38.4 15.9 4.3 4.4 0.4 26.0 7.8 0.2 4.9 3.0 39.4 11.2 9.6 8.9 4.6 15.6 2.7 5.3 1.8 3.0 5.8 13.3 12.6 12.7 18.4 31.0 10.7 10.8 7.3 6.4 2.0 2.5 5.2 13.4 10.2 14.1 10.2 18.8 29.0 3.8 12.3 2.4 21.9 2.3 3.2 11.5 9.0 0.4 1.6 23.4 8.3 14.7 10.6 2.8 7.6 26.1 29.1 7.2 21.2 17.1 16.6 19.4 13.3 14.7 12.9 8.9 6.6 9.8 11.0 2.2 0.7 2.5 17.8 1.4 4.5 3.5 0.0 33.9 1.7 35.3 14.7 5.5 12.9 23.3 20.0 103.8 9.9 17.8 21.9 33.3 99.7 0.0 5.8 4.3 10.7 12.3 4.6 30.4 6.8 90.2 15.5 28.1 24.3 15.2 3.5 29.9 1.8 0.0 5.3 1.2 10.6 1.0 30.2 0.0 18.6 8.9 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156963-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Cardiomyocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 85.5;fHDF/TERT166: 115.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Yes No Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 31.7 31.4 24.9 15.2 23.0 5.6 23.7 7.8 15.6 19.3 20.6 25.5 13.7 11.3 24.5 11.4 18.7 12.8 15.1 74.7 23.9 20.4 16.1 16.0 22.3 14.9 26.8 13.4 17.2 11.1 14.6 17.6 40.5 18.0 20.0 13.2 11.8 13.5 21.3 29.9 10.6 15.8 30.9 34.9 16.4 11.7 9.5 22.6 18.0 14.9 12.8 12.5 27.4 20.7 1.6 2.1 6.1 2.2 3.8 14.7 1.4 7.1 1.9 2.3 0.9 6.0 6.9 2.7 85.5 35.8 34.8 16.5 3.5 7.1 2.6 6.2 115.4 2.0 4.4 3.5 4.6 35.2 8.1 5.0 3.5 8.2 1.4 7.2 5.9 7.3 4.3 4.0 22.9 6.9 13.0 6.6 21.6 2.7 6.4 15.9 2.2 5.1 3.5 1.2 5.7 1.4 2.7 5.7 4.5 5.9 3.7 1.4 2.7 14.2 8.2 9.5 3.4 6.0 5.4 14.5 9.8 8.3 28.0 8.9 4.5 4.1 1.7 4.2 5.4 7.5 1.9 2.2 3.0 3.2 1.9 14.7 1.3 3.6 4.6 2.1 1.6 2.9 3.6 6.1 3.8 1.7 1.4 6.0 1.4 24.9 23.0 7.8 15.6 23.9 20.4 26.8 13.4 18.0 22.6 26.8 24.2 12.3 15.3 45.6 9.4 150.0 10.2 25.4 21.6 17.4 13.7 11.6 10.0 8.8 2.1 26.3 19.8 46.7 16.9 13.3 24.9 20.4 8.1 19.2 15.2 3.2 19.0 35.0 42.5 1.7 27.0 23.7 28.7 16.2 19.6 10.0 34.6 17.3 36.0 11.6 25.0 19.4 44.2 7.5 5.7 43.0 53.8 20.1 14.9 22.4 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 14.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved NA NA "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 3.5 4.6 2.9 11.9 4.5 2.0 4.3 1.7 4.9 5.3 4.0 4.7 1.4 4.2 2.1 5.0 4.8 5.9 4.4 1.6 2.9 1.9 10.4 6.9 5.7 7.8 2.3 2.1 4.4 6.4 8.5 9.7 8.7 5.6 5.6 3.2 5.2 5.3 4.1 0.9 4.4 6.5 1.7 3.0 8.4 4.9 4.9 1.4 4.8 10.7 3.5 15.6 4.5 3.0 4.7 14.7 3.2 1.0 1.3 1.1 0.8 2.2 3.5 3.8 3.0 2.1 2.3 11.6 1.0 2.2 1.4 1.8 5.6 5.2 13.5 3.8 2.9 2.6 3.9 5.5 5.0 1.4 3.5 6.8 3.0 5.7 10.2 3.6 1.9 4.0 5.2 1.9 2.6 6.2 2.0 1.0 2.0 4.4 1.4 1.5 4.8 1.8 3.5 3.5 3.8 1.1 4.9 2.4 6.0 7.5 5.9 6.8 1.6 3.2 6.6 1.6 5.2 9.9 2.5 0.9 1.3 2.5 1.7 1.0 1.6 1.8 9.1 2.2 1.7 3.2 3.2 0.9 1.2 0.8 0.4 0.9 3.0 0.7 0.7 0.1 4.7 0.8 1.1 0.5 1.3 1.0 14.7 0.5 0.8 2.9 4.5 1.7 4.9 2.9 1.9 2.3 2.1 5.6 1.4 8.9 17.1 11.5 7.4 2.5 2.6 1.6 5.1 10.7 13.6 24.4 7.9 14.3 6.6 4.7 7.6 2.1 10.7 0.0 5.3 8.0 4.1 6.9 25.5 4.9 3.3 1.6 9.9 4.3 3.3 1.5 3.1 4.0 3.3 3.6 10.2 1.7 3.7 13.3 2.5 3.0 1.6 0.0 1.2 4.8 5.1 1.4 9.3 4.6 12.4 3.4 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved Approved Mitochondria NA NA 190000 Mitochondria "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 17.0 20.4 12.7 17.7 17.4 7.3 15.1 15.4 13.3 18.6 18.7 18.3 23.5 14.0 25.0 13.8 15.6 20.0 15.9 23.5 11.4 8.7 14.0 13.3 12.9 16.2 20.2 10.6 25.6 15.7 24.7 23.6 14.3 13.0 15.3 8.1 15.4 12.4 18.9 36.2 10.6 15.3 24.7 14.5 14.7 14.8 16.6 18.2 21.5 17.0 14.1 14.4 23.6 18.7 6.0 6.4 7.5 5.4 5.5 6.2 3.1 10.1 12.0 15.2 17.0 19.6 26.9 17.4 16.5 11.7 8.1 7.9 10.1 8.9 17.5 0.1 11.3 6.7 14.0 11.6 6.4 9.0 14.2 6.7 8.5 12.0 7.3 12.8 5.1 11.4 18.3 7.6 8.4 6.4 21.5 10.1 12.1 9.6 11.3 9.7 1.1 10.8 5.2 9.0 12.9 6.1 17.5 19.4 9.0 6.1 12.5 7.4 18.7 13.3 6.4 12.8 16.7 15.9 14.8 15.3 12.3 5.2 14.3 6.4 18.3 19.5 17.6 9.0 8.7 8.3 7.5 5.4 5.8 4.2 5.0 5.9 2.8 4.8 3.9 6.4 6.0 6.2 5.9 5.5 5.5 3.5 1.8 2.6 3.1 12.7 17.4 15.4 13.3 11.4 8.7 20.2 10.6 13.0 18.2 11.9 33.3 10.4 7.4 7.8 16.5 47.6 5.1 14.7 19.4 10.4 33.4 13.4 6.6 5.0 9.2 14.3 10.6 0.0 4.3 13.7 11.8 6.1 15.1 28.4 12.0 12.7 5.2 17.8 18.7 6.4 23.0 12.6 3.3 6.4 10.5 12.1 5.0 9.0 24.8 7.8 22.6 0.0 12.3 23.8 12.8 8.9 11.7 10.0 10.6 4.8 NEURL1 "h-neu, neu-1, NEURL, RNF67" ENSG00000107954 "Neuralized E3 ubiquitin protein ligase 1" O76050 10 103493979-103592552 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Translation regulation, Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 37.1;skeletal muscle: 83.5" "Cell type enhanced" "Detected in many" 15 "Early spermatids: 105.4;Late spermatids: 383.1;Paneth cells: 157.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "intermediate monocyte: 16.0;non-classical monocyte: 37.1" "Lineage enriched" "Detected in many" 17 "monocytes: 37.1" "Cell line enhanced" "Detected in some" "BEWO: 13.0;HeLa: 7.7;HMC-1: 6.6;JURKAT: 6.9;SCLC-21H: 16.4;SiHa: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044204 Enhanced NA NA "HPA044204: AB_10959383" "unprognostic (1.21e-2)" "unprognostic (8.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.58e-4)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (5.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (4.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (8.61e-3)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.91e-4)" "unprognostic (3.23e-1)" 1.1 3.9 18.5 3.0 17.5 2.0 1.0 28.2 27.2 6.1 8.6 0.6 1.2 7.7 13.2 11.0 3.6 2.1 2.0 1.1 12.0 7.6 1.3 1.1 1.3 1.3 4.5 18.9 2.1 12.8 2.9 6.5 13.3 6.1 2.8 7.3 7.8 1.5 1.7 83.5 1.9 11.7 11.7 1.2 2.0 4.4 7.5 2.1 0.0 1.2 8.5 1.1 9.2 1.7 0.4 2.1 1.0 37.1 0.2 0.4 1.2 0.8 0.2 1.3 0.0 0.4 0.1 13.0 0.5 0.8 0.2 0.1 0.3 0.3 0.4 0.7 0.1 0.9 0.7 0.4 0.2 0.1 0.3 0.7 0.2 7.7 0.6 0.0 0.3 6.6 0.2 0.5 0.1 0.6 0.2 0.0 6.9 2.1 0.4 0.2 1.1 1.3 0.8 0.0 0.5 3.9 0.2 0.6 1.4 0.0 0.5 16.4 5.6 8.2 0.0 0.4 2.5 0.7 1.5 0.0 0.1 0.9 0.2 0.2 0.9 0.2 0.3 0.5 0.0 0.3 0.2 1.0 0.2 0.3 16.0 0.4 0.4 0.4 0.4 2.1 0.3 0.4 0.3 1.0 0.2 37.1 1.7 0.1 1.2 18.5 17.5 28.2 27.2 12.0 7.6 4.5 18.9 6.1 2.1 0.0 1.1 1.4 1.3 0.5 42.1 1.2 0.0 0.0 0.0 0.0 88.4 3.4 0.0 9.1 105.4 1.0 6.9 0.0 0.6 10.0 1.9 0.5 0.0 0.0 4.2 3.2 75.1 0.0 4.1 383.1 5.2 2.0 0.0 0.0 92.0 6.4 0.9 157.0 4.9 0.0 83.3 6.5 0.6 47.6 28.8 1.6 94.9 3.9 7.8 0.5 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641266-172691540 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Endothelial cells: 32.6;Enterocytes: 45.0;Ito cells: 36.2;Leydig cells: 50.6;Paneth cells: 33.1;Smooth muscle cells: 30.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 27.6;T-47d: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 26.6 11.8 7.5 10.3 3.2 1.5 23.9 0.6 7.0 21.4 17.5 5.6 31.2 5.7 26.7 24.7 14.0 15.8 23.0 19.2 10.7 4.2 7.6 4.4 10.5 7.8 3.1 3.2 20.9 4.8 4.1 6.0 5.1 2.7 20.7 11.6 6.1 4.9 28.4 12.3 14.7 12.1 29.1 1.5 0.6 5.9 6.6 2.8 3.6 7.2 13.9 5.4 16.0 30.8 0.0 0.6 0.0 0.2 0.0 0.2 0.0 4.5 2.4 1.3 5.8 0.4 0.2 0.1 5.1 2.3 2.7 4.0 8.7 2.1 0.0 1.4 3.3 3.3 1.3 0.5 2.3 1.8 8.3 0.3 6.2 8.3 0.0 0.4 0.0 1.9 0.0 9.9 0.6 2.7 0.8 0.4 0.9 0.0 2.0 5.8 5.0 1.4 0.1 0.8 2.0 0.2 27.6 6.1 0.9 0.1 1.0 1.0 5.9 4.9 7.8 0.2 2.4 13.0 0.9 0.8 2.0 12.2 1.4 3.2 0.8 0.2 0.0 5.9 0.1 1.8 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.5 3.2 0.6 7.0 10.7 4.2 3.1 3.2 2.7 2.8 0.0 3.4 0.0 0.6 4.2 0.1 7.8 0.0 8.1 4.5 0.0 0.0 0.2 0.0 0.3 1.9 32.6 45.0 0.0 0.6 0.2 3.5 1.8 0.0 0.5 0.2 0.0 13.4 36.2 2.4 4.1 50.6 1.8 6.8 1.0 12.5 0.7 3.5 33.1 11.7 0.8 0.3 25.8 30.8 2.1 1.5 4.6 0.1 0.0 15.7 0.9 NGLY1 "FLJ11005, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 518.0;Late spermatids: 684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" NA NA "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" 10.7 14.4 11.4 19.6 11.4 12.9 15.0 17.1 15.0 9.5 12.4 6.9 11.7 10.5 10.2 13.8 13.2 8.4 10.5 14.3 12.0 9.0 12.8 18.1 13.9 17.4 9.5 12.5 10.6 20.7 9.0 11.3 8.7 11.0 10.9 15.2 7.8 12.4 18.0 46.6 9.0 11.2 8.7 10.1 14.6 11.9 42.0 9.0 18.0 10.3 10.9 18.1 11.5 10.6 26.1 39.7 19.9 10.8 22.6 14.7 10.3 12.5 10.7 6.0 12.7 11.6 10.7 8.6 10.8 9.1 13.6 12.3 6.6 9.6 31.9 12.3 9.1 14.1 5.7 20.2 5.7 18.5 15.0 8.6 23.7 8.2 10.7 13.0 21.8 13.0 9.5 7.6 14.9 14.0 14.8 14.5 15.7 22.4 23.0 13.8 5.5 25.9 12.9 8.1 14.7 19.5 26.5 7.9 22.7 12.5 15.4 3.7 4.5 15.6 15.1 10.0 12.0 14.3 18.3 9.8 10.7 11.1 12.9 13.9 28.3 24.4 22.2 12.9 23.7 8.4 19.9 10.8 18.9 13.7 10.1 14.7 26.1 13.8 12.6 16.3 21.7 14.0 13.6 12.8 22.6 8.4 39.7 10.4 10.3 11.4 11.4 17.1 15.0 12.0 9.0 9.5 12.5 11.0 9.0 17.9 12.9 39.7 20.7 11.2 21.6 22.4 22.9 28.1 15.9 5.2 11.8 36.2 29.9 26.6 518.0 20.1 20.2 0.0 38.1 28.0 19.8 22.0 19.7 22.7 21.1 11.1 6.9 15.4 16.4 684.0 13.8 24.8 23.6 20.8 27.3 19.8 25.0 24.6 14.9 29.8 20.4 0.0 14.6 73.4 43.7 12.0 47.4 33.3 28.9 19.0 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122687 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" 5 "Exocrine glandular cells: 3.2;Intestinal endocrine cells: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 9.2;K-562: 7.8;SCLC-21H: 8.2" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 2.5 3.6 5.0 1.8 6.5 2.1 4.6 2.6 8.5 1.9 3.3 7.1 1.7 3.2 2.0 6.1 2.4 3.5 2.7 3.9 5.0 5.1 1.9 9.0 5.1 4.7 5.4 3.9 3.5 12.2 2.4 2.8 1.0 5.2 3.4 3.0 3.3 5.1 2.8 5.2 8.5 4.3 1.8 5.4 2.4 3.0 2.1 3.8 2.4 3.6 0.9 1.8 2.5 1.8 3.3 7.2 0.6 7.2 2.2 2.5 2.6 3.3 2.0 0.8 0.1 1.8 1.7 0.0 3.5 1.1 1.3 0.7 0.1 2.8 0.1 9.2 2.5 0.2 4.0 0.0 2.2 1.0 0.1 1.2 0.5 1.1 0.2 2.8 0.0 2.2 2.9 3.4 1.3 1.2 0.8 2.8 0.0 7.8 0.1 2.8 3.6 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.1 1.9 3.6 8.2 0.1 6.9 5.8 2.0 0.8 4.2 2.2 0.5 0.2 1.8 2.4 0.0 0.1 0.0 0.1 0.1 0.0 3.5 0.5 6.6 0.6 1.1 7.2 1.2 3.3 1.7 0.8 7.2 2.3 2.5 1.6 0.5 2.2 3.2 0.9 1.8 2.6 5.0 6.5 2.6 8.5 5.0 5.1 5.4 3.9 5.2 3.8 0.0 2.1 0.0 1.0 1.6 0.1 0.4 0.0 0.0 2.3 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.3 0.0 3.2 0.0 0.2 0.1 1.1 1.0 1.1 0.0 3.4 0.0 0.6 0.0 0.6 0.9 1.7 0.0 0.0 0.5 1.7 0.0 0.0 1.1 1.1 0.0 0.4 0.2 0.0 1.6 0.3 0.0 0.4 0.3 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600614-42648741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: AB_2681540" "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favorable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.01e-4)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.05e-5)" 12.9 14.4 9.8 18.8 22.2 16.3 15.9 42.0 12.3 18.8 10.4 18.5 15.4 11.8 27.2 17.4 11.0 12.0 13.1 11.2 10.9 10.5 9.5 9.7 14.6 15.5 14.5 11.3 22.7 18.4 19.2 26.9 11.1 14.1 12.9 11.1 20.4 13.2 19.5 12.0 20.0 13.3 19.4 15.0 18.5 10.1 17.8 13.8 20.6 14.9 10.9 19.4 12.9 13.9 9.3 8.5 11.7 10.0 11.1 10.2 3.6 8.9 5.2 17.2 7.0 10.3 12.6 9.7 14.6 3.7 6.1 8.3 9.0 7.2 14.2 7.0 4.4 6.0 7.9 10.1 3.7 12.5 7.1 8.5 18.2 16.3 14.6 4.4 14.0 12.0 5.1 7.2 12.0 4.6 11.1 10.7 3.4 18.3 11.0 11.5 3.7 9.5 13.7 14.8 4.8 7.6 10.1 7.7 5.8 8.5 6.9 6.1 3.6 15.7 6.5 2.4 8.0 9.6 10.2 17.1 10.9 8.0 11.9 14.0 9.5 13.3 9.9 5.8 17.2 6.7 9.2 6.2 11.7 10.2 7.7 9.4 8.9 9.8 8.5 4.7 9.3 10.0 8.7 9.1 11.1 10.0 8.5 8.3 3.6 9.8 22.2 42.0 12.3 10.9 10.5 14.5 11.3 14.1 13.8 101.3 122.0 67.1 53.1 52.4 190.3 63.1 50.9 45.5 75.1 83.7 231.7 56.8 14.9 39.7 13.6 120.9 75.7 23.3 34.0 42.2 62.5 58.7 92.6 44.7 39.4 125.5 69.0 103.2 49.9 13.7 155.3 72.2 49.0 62.3 51.5 160.2 38.7 44.6 126.2 9.7 283.7 90.5 58.5 210.1 183.7 50.1 26.2 126.8 54.0 42.1 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Bipolar cells: 93.3;Cone photoreceptor cells: 145.3;Early spermatids: 243.8;Late spermatids: 250.1;Rod photoreceptor cells: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 32 "basophil: 17.6" "Lineage enriched" "Detected in single" 32 "granulocytes: 17.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: AB_2683160" "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 6.4 30.5 19.4 10.9 14.1 7.4 7.5 7.5 38.2 6.2 6.7 8.3 14.4 8.3 5.7 8.8 4.5 5.1 8.2 8.5 18.2 12.0 13.0 8.2 7.1 11.7 15.2 23.6 4.6 11.5 20.8 9.4 9.1 7.0 6.7 7.1 12.7 5.8 17.4 4.9 4.5 8.3 4.6 15.3 10.1 7.0 17.4 7.5 10.9 13.2 3.7 11.0 7.2 4.4 0.5 0.3 17.6 0.3 0.1 0.5 0.2 4.6 5.4 13.0 4.5 2.8 3.6 5.8 4.7 4.8 7.8 6.0 27.1 4.2 6.3 7.1 3.8 9.9 4.4 9.2 8.5 9.0 14.6 5.8 24.8 5.0 4.6 4.7 5.2 25.6 4.7 5.3 5.1 6.2 7.6 9.1 18.0 9.5 7.7 7.1 5.5 13.4 6.0 5.0 9.1 2.7 11.2 8.4 4.6 14.2 5.7 9.5 3.6 7.1 6.8 29.1 16.4 10.6 8.3 9.3 5.6 7.6 4.6 9.4 9.0 8.6 6.1 5.5 5.7 6.1 17.6 0.2 0.2 0.3 0.3 0.1 0.5 0.4 0.4 0.2 0.3 0.2 0.5 0.1 0.1 0.3 0.3 0.4 0.2 19.4 14.1 7.5 38.2 18.2 12.0 15.2 23.6 7.0 7.5 20.8 5.9 4.7 3.5 4.7 93.3 23.0 10.2 6.7 4.5 31.4 145.3 2.5 1.7 3.3 243.8 10.6 5.9 0.0 5.5 3.0 3.7 5.4 24.2 8.9 7.2 35.0 27.1 10.4 14.2 250.1 5.2 5.0 15.1 4.6 9.4 9.4 5.7 7.0 2.5 6.3 92.4 12.9 3.9 25.8 9.5 4.3 5.4 5.1 8.3 5.8 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722196-65871725 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.7;intermediate monocyte: 5.9;myeloid DC: 4.1;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;monocytes: 5.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 53000 Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 4.5 2.4 7.6 4.7 10.5 2.9 7.3 2.8 11.9 4.1 6.8 5.8 1.0 2.4 5.8 5.0 5.2 3.3 2.7 5.1 7.2 7.6 7.5 18.9 3.4 5.1 8.7 8.5 4.0 11.0 3.6 2.4 4.9 9.8 5.4 6.5 2.0 4.3 2.6 15.0 5.7 5.3 5.5 10.9 5.8 7.5 2.4 6.2 1.8 5.5 7.9 4.0 4.3 3.3 0.9 4.1 0.6 5.9 0.9 0.7 1.8 9.2 8.9 5.3 8.7 6.7 11.5 10.6 9.4 4.0 5.5 6.0 5.1 5.5 13.2 11.9 11.2 11.1 7.4 6.8 14.4 9.7 3.9 4.6 3.6 6.7 12.8 5.8 8.3 2.2 8.7 7.9 7.6 9.1 4.7 15.5 5.9 7.8 2.8 11.9 7.1 5.7 7.5 16.1 4.7 2.6 6.7 11.2 20.9 9.1 4.1 16.4 8.5 7.6 7.8 7.7 14.9 9.3 9.9 8.9 3.7 4.4 5.4 7.0 2.4 4.8 5.8 5.7 16.4 5.5 0.2 4.7 0.2 0.2 5.9 0.3 0.9 0.4 0.3 4.1 0.9 0.7 0.5 0.6 0.9 4.1 0.2 0.1 1.8 7.6 10.5 2.8 11.9 7.2 7.6 8.7 8.5 9.8 6.2 6.0 3.2 1.5 5.1 5.0 0.6 13.2 10.2 2.7 11.4 12.2 3.9 5.2 5.0 15.3 0.2 5.0 20.6 0.0 12.3 12.1 5.2 8.8 15.0 26.4 24.7 4.8 1.7 5.5 23.4 0.0 4.0 8.4 1.7 2.8 7.1 13.2 23.5 10.7 2.1 17.4 3.5 0.0 3.1 1.4 4.3 4.5 2.4 0.9 7.1 5.5 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 45051610-45109016 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Hepatocytes: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.8 32.6 44.9 28.2 37.3 12.0 26.1 34.5 64.3 23.7 24.4 17.2 22.9 23.4 27.3 29.3 26.6 30.9 17.3 26.8 37.7 29.6 28.8 36.6 26.7 27.2 27.7 43.6 29.3 21.8 41.6 23.7 32.7 38.1 23.7 23.1 18.1 34.9 30.1 75.5 28.8 24.8 30.1 36.6 28.2 23.4 26.1 34.0 20.7 29.4 18.6 30.9 25.1 43.3 10.2 18.2 7.6 9.3 7.4 10.0 3.3 17.0 22.6 19.5 17.2 35.3 22.8 20.5 19.0 25.2 37.1 30.6 25.2 14.7 20.5 27.6 26.1 26.6 16.1 33.5 26.6 34.4 52.1 23.4 20.4 15.1 24.8 23.2 26.3 24.6 28.7 24.2 27.5 21.9 19.9 24.8 21.0 32.3 10.4 20.6 14.6 31.9 17.9 18.2 31.4 23.6 21.9 29.1 15.6 29.3 15.8 16.3 14.7 12.0 11.0 17.2 34.8 23.7 20.9 19.9 22.7 17.4 18.2 25.3 16.2 23.0 20.5 24.3 14.8 23.9 6.5 8.1 7.6 7.9 9.3 7.2 10.2 7.8 9.3 6.6 7.6 10.0 7.6 5.3 7.4 6.9 18.2 7.5 3.3 44.9 37.3 34.5 64.3 37.7 29.6 27.7 43.6 38.1 34.0 35.7 35.1 55.6 14.2 12.4 85.1 38.9 94.3 16.0 27.3 66.3 110.0 63.6 66.3 62.0 17.1 41.3 50.2 116.8 61.6 49.6 39.9 11.1 22.0 304.8 40.7 122.3 48.9 77.3 77.9 6.8 50.9 41.1 10.1 108.2 32.8 38.5 58.3 45.6 48.1 45.3 119.2 58.2 14.4 60.6 32.8 12.3 68.4 41.5 52.5 15.0 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "granulocytes: 89.2;Hepatocytes: 122.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 8.7;eosinophil: 7.9;gdT-cell: 7.2;MAIT T-cell: 12.9;memory CD4 T-cell: 11.5;memory CD8 T-cell: 8.3;naive CD4 T-cell: 14.7;naive CD8 T-cell: 9.3;NK-cell: 12.9;T-reg: 17.5" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;NK-cells: 12.9;T-cells: 17.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 33.8;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 29.3 5.4 18.9 6.5 17.3 3.8 19.2 35.6 25.3 12.0 9.9 6.0 4.7 7.4 14.5 5.0 8.2 8.9 8.1 9.6 12.8 9.2 10.8 18.5 7.2 9.0 8.8 15.0 18.2 7.1 28.5 7.9 5.1 10.3 10.7 10.7 8.3 5.8 9.4 18.8 11.5 11.9 12.5 10.3 10.1 8.8 14.5 9.9 23.7 6.9 4.5 8.9 10.1 20.1 1.9 0.3 8.7 0.5 12.9 17.5 3.9 2.8 3.6 4.2 3.1 11.5 12.4 0.8 6.2 5.0 5.7 7.8 3.5 12.7 0.1 4.3 33.8 15.7 3.5 3.7 3.5 9.6 3.7 4.8 7.6 1.8 4.8 7.7 0.5 28.3 11.0 3.6 8.1 2.4 20.9 22.0 5.3 3.6 0.5 21.2 3.5 5.8 1.4 3.1 3.2 3.5 4.3 6.2 0.5 4.2 0.6 1.2 4.8 7.5 1.2 2.0 3.7 3.8 2.3 49.0 5.7 8.4 25.0 4.4 4.3 4.5 0.3 7.0 2.0 4.1 8.7 0.3 7.9 7.2 0.4 12.9 1.4 11.5 8.3 0.3 1.9 14.7 9.3 1.2 12.9 0.5 0.2 17.5 3.9 18.9 17.3 35.6 25.3 12.8 9.2 8.8 15.0 10.3 9.9 8.9 9.1 18.2 17.3 14.7 21.8 11.1 76.5 5.3 14.8 26.2 3.9 0.8 8.3 23.8 6.4 20.4 30.1 46.7 16.8 2.1 11.6 13.9 89.2 122.4 2.4 19.1 17.2 24.5 6.9 9.6 20.1 6.5 11.8 13.6 9.9 12.0 21.3 12.2 19.4 44.1 14.9 0.0 15.3 7.4 50.5 12.9 2.2 38.3 16.9 13.4 NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554535 "Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036347 Supported "Nucleoli,Intermediate filaments" NA NA Nucleoli "Intermediate filaments" "HPA036347: AB_2675076" "unprognostic (3.03e-1)" "unprognostic (4.93e-2)" "unprognostic (4.99e-2)" "unprognostic (3.14e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (2.48e-1)" "unprognostic (1.31e-1)" "unprognostic (8.90e-2)" "unprognostic (1.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.80e-2)" "unprognostic (3.32e-2)" "unprognostic (3.40e-1)" "unprognostic (3.54e-2)" "unprognostic (4.65e-2)" 12.7 11.3 10.4 10.3 15.1 19.3 11.0 16.4 19.3 14.7 11.2 14.1 6.8 7.7 13.3 11.6 12.1 11.4 8.8 8.3 10.8 9.7 9.6 15.2 9.4 14.4 8.6 9.6 16.8 14.7 15.5 10.5 9.8 12.0 13.0 10.0 9.4 9.1 10.3 17.9 18.0 11.4 12.4 7.2 22.0 11.0 9.4 9.2 20.9 9.4 8.9 14.9 11.0 9.3 6.9 5.8 5.0 4.8 2.8 8.4 1.9 5.1 7.4 4.2 12.6 5.6 3.4 4.5 5.1 3.3 5.3 5.6 10.1 7.0 14.3 6.1 5.7 4.6 6.8 8.4 6.9 9.2 5.8 4.5 9.7 11.4 7.9 5.6 8.2 5.4 4.9 2.1 11.3 9.9 3.1 6.2 6.4 11.4 6.0 5.4 8.9 8.0 7.4 5.7 4.0 7.2 10.2 9.8 6.7 4.2 4.8 8.1 3.7 7.9 10.0 6.2 4.5 6.5 3.8 8.1 8.5 6.9 6.0 8.5 5.1 4.8 26.1 7.9 9.2 4.0 5.0 3.5 2.6 5.7 3.2 5.7 5.1 8.1 5.2 2.3 6.9 8.4 7.0 2.2 2.8 4.8 5.8 5.1 1.9 10.4 15.1 16.4 19.3 10.8 9.7 8.6 9.6 12.0 9.2 17.9 17.9 11.5 5.7 13.7 15.8 12.1 10.2 9.4 7.9 7.0 13.7 13.0 13.3 8.4 4.6 11.3 5.8 0.0 7.4 11.0 11.7 4.8 4.7 11.6 7.8 9.5 6.4 17.2 11.4 13.3 8.9 6.5 1.7 10.0 11.7 7.2 7.8 7.0 12.0 7.8 17.0 0.0 11.1 10.8 19.7 12.9 10.6 15.7 11.8 5.3 NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726951 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 142.1" "Cell type enhanced" "Detected in many" 8 "Cholangiocytes: 203.8;Ciliated cells: 259.6;monocytes: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 149.4;OE19: 264.4;SiHa: 169.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Supported Cytosol NA NA 310000 Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" 31.3 24.2 12.8 6.4 20.7 0.6 77.1 2.7 9.1 7.6 23.2 7.8 5.7 29.5 3.9 8.6 36.3 8.2 77.2 9.3 9.9 7.5 44.7 1.2 17.2 6.9 11.3 6.0 3.7 2.5 7.0 3.7 3.5 25.5 9.8 20.8 20.2 10.5 7.6 7.6 2.3 17.7 22.7 10.4 6.0 142.1 3.8 4.9 0.1 25.7 69.7 16.2 21.2 18.9 5.2 3.2 0.9 3.2 15.1 12.3 4.4 13.1 149.4 12.5 55.9 31.2 45.3 4.7 22.3 40.0 23.0 35.6 18.1 85.3 0.4 26.5 115.2 40.2 13.8 4.8 25.1 11.8 5.3 0.2 0.6 37.0 131.8 41.5 3.1 10.7 10.6 15.9 39.9 4.6 34.6 57.0 1.0 5.4 0.9 122.9 42.6 0.6 5.7 6.6 264.4 14.5 1.0 2.6 6.1 45.9 47.9 4.5 1.0 169.7 24.1 99.3 14.9 39.0 10.5 38.6 23.2 9.6 8.7 17.5 0.7 2.9 0.6 29.7 1.7 114.7 0.6 3.2 0.2 5.7 0.3 2.9 5.2 6.6 7.2 3.2 2.1 2.1 4.7 0.9 15.1 0.3 1.2 12.3 4.4 12.8 20.7 2.7 9.1 9.9 7.5 11.3 6.0 25.5 4.9 23.8 13.4 1.4 19.5 4.6 4.0 4.5 203.8 259.6 28.4 40.1 3.9 2.1 124.3 22.1 0.3 55.5 72.0 0.0 134.0 3.1 13.1 25.1 19.6 3.2 12.5 3.2 19.5 31.9 3.3 0.9 23.3 8.2 16.9 222.8 60.8 7.6 63.7 49.1 11.3 24.5 10.7 6.5 17.6 0.2 1.5 4.0 1.6 4.4 33.4 25.4 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3028869 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 14 "monocytes: 212.8;Proximal tubular cells: 716.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 62.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol NA NA 6500000 Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavorable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 24.7 45.6 18.2 11.0 17.6 27.2 21.9 44.3 28.1 12.9 11.5 8.9 8.8 15.6 10.4 15.4 12.1 11.2 12.8 38.2 16.0 13.3 82.9 47.0 11.7 17.5 17.0 23.5 13.5 18.4 12.1 9.3 12.1 24.5 12.7 9.0 18.0 24.5 13.5 41.3 20.2 15.5 10.7 11.8 15.3 12.8 7.7 12.5 7.0 11.9 13.9 7.9 10.4 11.0 3.2 16.6 62.1 25.2 7.3 9.3 13.1 12.7 21.6 13.2 29.0 23.3 13.8 14.2 12.4 15.9 11.5 12.9 22.7 4.9 11.2 45.3 21.3 26.9 9.8 13.5 8.6 9.0 26.1 11.5 6.9 26.5 22.7 19.0 6.9 22.1 8.5 10.3 13.9 13.0 16.5 11.1 14.6 39.2 6.7 9.5 28.4 7.9 12.8 17.9 26.9 18.0 14.7 15.7 32.7 17.3 6.8 2.8 5.1 18.8 8.0 39.4 24.7 11.0 4.8 19.1 10.8 4.2 14.4 5.4 14.6 33.1 3.4 12.7 21.0 21.3 5.6 25.2 13.5 9.2 15.7 6.6 3.2 8.3 8.3 16.6 2.1 5.0 5.7 62.1 7.3 13.9 1.7 9.3 13.1 18.2 17.6 44.3 28.1 16.0 13.3 17.0 23.5 24.5 12.5 8.9 17.3 8.1 35.0 31.3 32.4 60.5 50.9 22.7 10.3 24.4 9.8 36.3 137.6 19.8 39.2 32.9 25.6 23.3 55.3 41.3 45.4 32.3 12.8 167.7 66.5 39.7 4.6 20.3 34.6 38.3 33.1 71.3 64.1 212.8 19.0 47.3 40.8 17.3 38.5 716.7 18.8 25.8 46.2 7.0 10.1 36.0 26.1 17.3 20.9 42.3 NR1D1 "ear-1, hRev, Rev-ErbAalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092787-40100725 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Basal keratinocytes: 57.4;Bipolar cells: 62.8;Suprabasal keratinocytes: 70.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "MAIT T-cell: 16.3" "Group enriched" "Detected in many" 6 "monocytes: 4.2;T-cells: 16.3" "Cell line enhanced" "Detected in many" "Karpas-707: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 19.4 15.1 12.2 7.6 14.7 6.0 30.5 30.7 32.5 45.9 13.9 6.4 17.3 15.2 16.5 6.1 16.8 10.7 8.2 43.7 8.8 5.2 9.8 14.8 12.7 8.8 4.7 11.7 33.3 8.3 4.8 10.9 7.3 6.1 15.5 5.5 28.0 53.0 18.6 51.2 79.3 8.8 27.3 6.0 7.8 7.9 7.3 6.8 1.8 13.9 11.7 10.6 28.0 25.4 1.8 1.1 0.1 4.2 0.8 16.3 1.5 2.8 4.2 0.9 3.4 5.0 3.4 1.2 6.4 10.5 2.1 2.7 2.7 10.5 3.5 3.9 7.3 7.1 8.3 2.2 9.6 1.6 3.0 2.3 2.5 4.2 7.1 8.1 3.8 3.8 7.5 7.0 7.2 15.5 7.0 2.6 4.2 3.7 32.9 2.0 2.0 5.6 3.3 1.6 5.8 6.7 4.0 1.3 10.8 2.9 2.6 2.8 1.6 4.0 5.3 6.5 1.6 2.5 3.2 2.6 9.5 9.4 7.7 5.0 11.9 18.1 1.4 12.9 2.2 7.3 0.0 0.4 0.0 3.9 1.6 16.3 1.5 4.9 5.7 0.9 1.8 4.5 3.2 0.1 0.8 4.2 1.1 6.5 1.5 12.2 14.7 30.7 32.5 8.8 5.2 4.7 11.7 6.1 6.8 3.0 1.3 2.4 32.1 57.4 62.8 5.2 5.1 0.0 6.8 1.8 3.9 2.2 6.6 11.9 1.6 10.5 24.4 0.0 10.1 1.0 6.6 19.6 2.3 25.4 2.2 39.7 7.9 4.3 1.8 0.4 20.1 4.6 18.6 0.0 4.3 27.8 19.9 6.6 36.4 6.9 29.2 6.5 18.6 0.5 7.5 70.9 1.9 6.1 3.6 21.3 NRF1 "ALPHA-PAL, EWG" ENSG00000106459 "Nuclear respiratory factor 1" Q16656 7 129611714-129757082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029329 Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA029329: AB_10601240" "unprognostic (2.80e-2)" "unprognostic (2.20e-3)" "unprognostic (4.51e-1)" "unprognostic (4.04e-2)" "unprognostic (2.01e-1)" "unprognostic (4.20e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.09e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (1.83e-2)" "unprognostic (2.06e-1)" "unprognostic (6.52e-2)" "unprognostic (4.20e-1)" "unprognostic (2.06e-3)" 14.8 7.3 10.9 18.9 13.0 20.3 18.2 22.2 11.1 15.4 10.3 12.6 16.0 9.0 15.7 10.4 10.1 18.7 10.0 12.3 11.5 11.1 10.0 7.8 11.2 18.7 12.1 7.7 24.4 15.2 13.5 10.9 12.5 11.5 11.5 9.9 11.7 13.8 13.9 19.3 12.2 10.7 14.0 9.6 14.2 8.7 17.2 15.2 29.2 13.8 11.4 16.1 12.8 19.2 8.8 7.0 13.1 7.0 5.8 13.3 6.2 11.8 9.7 14.1 12.4 8.5 6.8 11.2 8.3 8.6 12.7 9.9 11.7 7.9 13.6 6.1 9.3 8.0 9.1 15.1 8.4 13.0 13.0 10.8 11.3 8.2 7.9 6.2 13.8 11.3 5.8 7.9 12.5 12.1 7.3 9.3 13.3 13.6 10.5 7.7 10.8 27.0 13.0 13.1 10.9 8.7 17.2 11.4 12.1 7.2 8.7 12.2 13.3 12.5 13.0 8.4 12.0 8.1 13.2 7.2 7.2 10.0 8.4 15.2 11.5 11.4 24.2 7.6 12.8 13.9 6.1 5.5 13.1 11.4 6.9 13.3 7.7 8.7 10.5 7.0 8.8 9.6 8.2 11.4 5.8 7.0 4.7 9.1 6.2 10.9 13.0 22.2 11.1 11.5 11.1 12.1 7.7 11.5 15.2 3.0 6.2 3.7 2.8 6.0 10.2 5.1 5.1 13.4 5.7 3.5 9.8 2.1 0.0 2.1 0.3 6.7 3.2 0.0 3.1 3.5 3.7 4.4 4.7 4.7 2.6 9.5 6.4 8.0 5.6 1.4 4.9 5.8 5.0 2.8 5.0 5.6 2.4 5.8 4.2 2.2 10.4 6.5 3.6 6.7 6.0 6.8 2.9 9.2 3.9 2.6 NUAK1 "ARK5, KIAA0537, NuaK1" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063340-106140033 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;parathyroid gland: 18.6" "Cell type enhanced" "Detected in many" 12 "Cardiomyocytes: 46.0;Endothelial cells: 46.6;Ito cells: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "AF22: 23.1;EFO-21: 23.1;RH-30: 33.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" Yes No "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: AB_2683349" "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavorable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 8.2 1.8 4.2 2.0 13.0 0.0 5.5 9.9 20.1 4.6 1.7 24.3 1.1 1.0 5.8 1.6 1.9 3.6 2.7 11.3 5.1 3.3 2.5 2.4 4.9 1.5 8.7 8.4 3.2 1.2 18.6 1.9 2.5 7.6 3.6 2.2 2.3 1.8 3.7 9.4 11.6 1.5 6.3 5.5 1.1 1.5 1.3 9.3 1.1 1.8 1.1 1.4 3.4 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 5.0 3.4 23.1 0.2 9.3 1.0 10.7 5.7 3.9 4.4 3.3 1.7 0.8 0.0 23.1 10.4 1.9 4.8 4.8 4.6 2.1 0.0 1.3 0.0 3.7 1.8 1.9 0.0 0.0 4.8 3.1 2.5 0.8 7.6 8.4 0.0 0.0 16.8 3.1 0.5 0.1 0.2 4.5 0.0 1.4 0.0 33.2 4.0 2.5 5.9 2.7 0.1 2.6 0.8 0.2 15.9 1.2 0.1 6.2 3.8 12.9 1.4 6.8 0.0 0.0 0.3 1.1 0.0 3.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.0 9.9 17.5 5.1 3.3 8.7 8.4 7.6 9.3 0.0 3.7 0.0 32.0 11.9 30.8 46.0 2.5 0.0 5.7 7.0 0.0 0.4 3.3 5.0 0.3 46.6 0.0 23.3 8.3 4.1 9.2 4.4 0.0 10.5 6.1 38.1 0.0 119.1 9.7 1.7 3.7 1.3 10.1 1.0 2.0 1.7 11.7 0.0 2.8 1.4 2.6 0.0 14.4 0.7 5.5 13.9 0.2 0.9 0.9 3.7 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302059-205321791 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.4" "Cell type enhanced" "Detected in many" 6 "Collecting duct cells: 31.4;Ductal cells: 40.9;monocytes: 48.7;Mucus-secreting cells: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 42.4" "Group enriched" "Detected in all" 4 "B-cells: 15.3;granulocytes: 42.4;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BEWO: 22.8;RPMI-8226: 17.6;RPTEC TERT1: 20.9;SuSa: 24.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 1.4 2.8 0.8 12.5 2.4 8.3 0.9 9.2 1.5 18.9 10.4 3.9 2.4 13.6 2.7 3.8 31.3 3.4 1.3 1.1 1.7 1.0 14.5 3.6 16.2 20.3 5.5 1.5 3.3 13.2 0.1 2.3 7.2 2.0 1.5 7.5 9.8 9.7 2.0 0.7 12.9 15.4 0.9 2.7 10.4 2.0 5.6 2.4 5.5 14.5 20.1 31.7 2.8 24.6 15.3 3.6 42.4 5.6 5.7 10.7 5.4 2.1 11.6 7.1 0.3 0.1 0.3 22.8 2.8 2.9 7.6 3.1 12.2 0.4 3.4 1.7 0.7 12.5 4.2 1.6 4.2 3.3 0.0 0.2 0.0 0.7 2.1 4.9 0.0 0.0 1.3 3.1 4.4 2.6 1.7 0.3 0.0 0.4 0.9 1.4 0.5 0.0 0.0 4.5 1.5 0.3 0.0 0.5 17.6 20.9 0.0 1.1 0.1 0.8 3.3 0.3 24.7 3.3 0.0 0.8 2.7 1.3 0.3 4.3 6.2 0.9 2.1 0.4 0.0 1.0 3.4 5.6 13.2 3.9 4.2 2.8 14.2 4.8 4.6 3.6 15.3 10.7 8.1 42.4 5.7 4.1 1.4 2.8 5.4 0.8 2.4 9.2 1.5 1.7 1.0 5.5 1.5 2.0 2.4 6.0 5.0 9.1 0.8 1.0 0.8 1.4 20.4 2.7 0.0 31.4 0.0 6.5 5.0 40.9 1.7 2.2 20.3 0.0 1.5 27.7 4.0 1.8 0.0 2.9 4.6 0.0 10.4 1.3 11.7 1.2 0.0 6.5 6.8 48.7 40.0 1.7 7.2 2.9 0.0 15.0 0.5 6.5 2.5 0.5 0.9 4.6 3.4 4.5 18.7 0.2 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 28.8;seminal vesicle: 36.3;testis: 27.2" "Group enriched" "Detected in some" 5 "Ito cells: 54.6;Peritubular cells: 27.3" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 6.2;HAP1: 11.6;HEK 293: 8.6;NTERA-2: 21.3;SH-SY5Y: 4.6;SuSa: 4.4;U-2 OS: 10.7" "HPA047027, HPA057684" Approved Approved Cytosol NA NA Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 1.0 2.3 9.3 1.4 10.7 1.8 1.4 6.0 13.1 4.4 2.0 0.9 28.8 1.1 5.5 18.3 1.7 3.4 2.0 0.9 4.9 13.6 3.1 1.9 0.7 0.9 5.3 8.0 19.2 0.6 0.5 4.5 0.5 6.2 17.9 1.3 0.8 1.0 36.3 0.5 1.0 1.2 4.9 1.9 3.1 1.1 27.2 1.2 0.0 0.8 0.0 0.9 2.8 2.9 0.8 0.1 0.0 0.7 2.1 1.0 0.3 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 11.6 0.5 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 21.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.0 0.8 1.0 0.0 0.1 0.3 0.0 0.6 0.0 2.1 0.5 0.0 0.0 0.3 9.3 10.7 6.0 11.7 4.9 13.6 5.3 8.0 6.2 1.2 0.0 2.2 0.0 4.6 0.9 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.4 0.4 2.1 0.0 0.0 0.2 0.0 0.0 54.6 3.4 4.0 5.5 0.0 1.7 0.0 0.0 1.8 0.0 0.0 27.3 0.0 0.4 0.0 1.9 2.4 7.9 0.1 0.3 0.0 0.0 0.0 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496596 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;testis: 35.5" "Cell type enhanced" "Detected in many" 7 "Basal keratinocytes: 13.6;Peritubular cells: 19.4;Smooth muscle cells: 12.7;Spermatocytes: 13.4;Spermatogonia: 11.9" "Cancer enhanced" "Detected in many" "testis cancer: 17.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 3.7;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD8 T-cell: 3.1;NK-cell: 1.9" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 3.7" "Cell line enhanced" "Detected in many" "HAP1: 33.6;NTERA-2: 21.0" "HPA047027, HPA057684" Approved Approved Cytosol NA NA Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.2 5.4 11.2 1.4 21.9 1.6 2.8 7.4 26.1 3.8 2.6 0.8 4.4 1.7 5.9 4.3 1.9 1.6 2.2 0.8 7.0 17.9 0.9 0.6 0.8 1.1 5.3 12.7 10.0 3.8 0.5 2.8 0.6 5.3 10.1 1.4 0.5 1.3 11.9 0.6 1.7 1.5 5.0 1.8 0.9 0.9 35.5 1.1 3.6 1.0 0.2 1.1 1.7 1.6 0.5 0.4 0.0 0.2 1.9 3.7 1.0 0.0 0.5 10.1 0.0 8.8 11.2 0.0 4.7 1.3 0.2 0.2 0.0 0.0 0.0 0.2 5.7 5.6 0.7 33.6 11.5 0.1 0.0 2.2 0.0 0.0 0.0 4.1 0.0 2.2 6.8 4.6 3.0 11.1 1.9 7.9 10.4 0.0 0.0 9.5 0.2 12.7 0.0 21.0 0.0 8.5 0.0 7.1 0.0 2.1 0.0 0.0 6.6 2.0 0.0 1.8 5.2 0.0 0.0 4.6 2.4 11.1 0.7 0.0 4.4 2.0 7.2 1.5 0.0 0.9 0.0 0.0 0.0 3.7 0.0 1.4 0.5 1.2 1.9 0.4 0.3 0.2 3.1 0.0 1.9 0.2 0.2 0.0 1.0 11.2 21.9 7.4 14.9 7.0 17.9 5.3 12.7 5.3 1.1 0.0 0.0 0.0 4.8 13.6 1.5 0.4 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.2 9.4 0.0 0.0 0.0 1.3 0.9 4.1 9.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 10.2 8.1 0.6 5.0 0.0 0.0 0.9 2.2 0.0 19.4 0.0 0.1 0.0 12.7 13.4 11.9 8.0 0.2 0.0 0.0 1.1 NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343713 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "CAB004684: AB_425306, HPA044903: AB_2679139, HPA058623: AB_2683780, HPA067639: AB_2685877" "unprognostic (2.74e-3)" "unprognostic (2.58e-2)" "unprognostic (3.37e-1)" "unprognostic (2.05e-3)" "unprognostic (3.08e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (6.55e-2)" "unprognostic (7.06e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-2)" "unprognostic (2.80e-1)" "unprognostic (2.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" 12.0 18.0 21.6 9.6 21.9 10.2 20.6 14.0 25.5 14.9 14.9 26.0 15.4 12.8 15.7 30.2 14.5 20.5 12.3 16.0 17.3 18.6 10.7 17.5 11.2 12.2 19.5 19.0 28.3 20.9 12.0 19.0 14.1 20.5 16.5 15.3 15.7 16.1 13.0 30.8 13.9 10.1 14.7 20.7 11.3 13.0 8.6 19.1 18.6 3.8 13.2 13.8 14.4 12.1 16.6 15.8 14.3 12.2 14.3 22.2 11.2 23.8 9.8 12.8 4.5 8.8 16.3 9.2 11.5 26.1 13.3 14.0 6.7 11.3 6.6 9.6 14.3 5.1 10.5 11.5 28.4 13.6 24.8 10.3 14.3 18.5 12.6 25.6 11.0 5.9 16.5 18.4 17.2 32.4 18.2 27.5 23.2 4.0 27.1 19.5 14.8 11.4 10.3 7.9 10.6 28.3 14.8 8.0 16.7 13.1 7.8 2.6 10.4 18.7 7.1 10.8 12.0 5.7 11.9 17.7 11.5 10.4 7.5 11.9 6.1 9.9 11.7 14.4 10.6 14.3 14.3 12.2 9.7 11.7 10.3 16.7 16.6 19.2 15.2 15.8 15.0 22.2 19.6 4.5 14.3 10.7 14.7 19.7 11.2 21.6 21.9 14.0 25.5 17.3 18.6 19.5 19.0 20.5 19.1 3.0 5.5 15.9 17.8 25.0 13.1 18.6 43.3 17.4 11.4 15.7 5.9 33.9 74.6 22.6 9.7 21.5 18.6 0.0 34.7 35.6 23.1 17.1 12.7 31.0 32.5 7.9 21.4 30.1 38.4 21.8 25.3 23.9 21.9 32.5 29.1 16.2 26.1 26.9 18.0 39.6 12.8 25.8 23.6 35.8 17.5 27.6 15.8 25.3 31.4 15.7 NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392674 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol NA NA 110000 Cytosol "HPA047027: AB_2679907, HPA055953: AB_2682984" "unprognostic (2.42e-1)" "prognostic favorable (5.29e-4)" "unprognostic (9.63e-3)" "unprognostic (4.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-3)" "unprognostic (4.21e-2)" "unprognostic (4.93e-3)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" "unprognostic (4.63e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.24e-2)" 10.5 11.4 38.8 9.3 28.6 8.8 12.6 33.4 40.0 15.4 11.4 16.8 10.3 7.7 11.4 25.9 10.8 15.2 8.5 16.9 33.8 30.0 15.3 10.1 11.2 10.5 29.4 25.6 17.4 9.1 27.9 9.3 8.9 26.1 11.4 9.7 11.2 9.4 15.6 50.7 11.2 8.0 11.2 20.3 13.0 8.4 7.3 21.3 5.4 21.3 8.7 12.1 8.6 9.9 4.5 6.4 12.4 5.9 2.1 3.9 2.6 5.4 4.0 10.8 21.1 7.2 12.2 4.7 4.0 6.7 4.1 3.0 4.8 3.8 19.6 5.4 7.1 2.7 4.6 6.1 10.8 7.7 7.3 7.8 21.6 5.6 10.4 7.2 20.3 11.3 11.0 10.0 5.0 9.4 5.3 11.8 10.2 21.4 7.1 6.6 5.7 14.0 23.8 6.9 16.1 4.0 12.3 8.9 20.4 9.4 11.4 15.2 17.0 8.8 12.5 15.9 3.4 12.5 14.6 12.9 8.3 3.0 7.2 8.6 6.1 14.1 14.4 5.0 20.8 12.9 1.9 5.8 12.4 3.4 5.9 3.9 3.4 3.4 3.2 6.4 4.5 3.2 3.7 4.1 2.1 5.8 3.2 2.4 2.6 38.8 28.6 33.4 40.0 33.8 30.0 29.4 25.6 26.1 21.3 14.9 22.4 43.5 59.4 53.1 115.6 43.3 63.7 46.8 14.8 40.1 111.9 28.0 11.6 15.4 3.0 55.9 18.4 0.0 24.5 26.3 42.3 39.4 12.8 52.1 67.2 160.5 47.2 84.7 91.0 4.0 34.8 58.5 50.6 22.6 24.7 115.6 20.8 19.8 59.4 19.2 125.0 58.2 46.4 44.7 78.0 52.7 16.4 20.1 25.2 59.3 NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.7" "Cell type enhanced" "Detected in all" 5 "Muller glia cells: 411.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol NA NA Cytosol "HPA017593: AB_1854703, HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (1.44e-2)" "unprognostic (2.15e-1)" "unprognostic (4.40e-3)" "unprognostic (4.25e-1)" "unprognostic (3.08e-3)" "unprognostic (1.42e-1)" "unprognostic (8.12e-2)" "unprognostic (9.09e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (5.01e-1)" "unprognostic (8.32e-3)" 17.2 29.7 14.1 14.7 9.5 37.4 20.4 7.0 29.0 15.2 14.7 6.7 17.5 6.5 13.6 24.8 13.7 12.8 40.0 140.7 12.4 12.4 47.9 11.2 11.3 10.9 9.4 13.7 41.9 21.1 16.1 11.9 19.2 13.9 27.1 16.9 25.1 65.2 14.8 40.3 8.1 12.7 13.8 12.6 9.2 13.1 10.6 6.3 14.6 25.5 22.4 8.9 19.6 32.9 6.0 4.1 13.6 3.6 7.6 6.6 2.5 5.8 5.0 9.1 10.2 34.0 14.1 11.5 16.3 13.0 9.4 6.9 46.9 14.6 8.2 3.6 13.0 6.1 7.4 25.5 8.2 14.4 12.5 5.4 30.7 4.4 23.9 32.7 15.9 7.4 30.5 27.5 9.6 21.6 47.1 53.1 14.8 31.1 11.5 10.7 6.0 14.8 15.2 14.4 14.4 12.0 12.4 8.2 8.8 11.2 42.3 7.4 9.5 13.2 25.9 36.5 15.3 18.8 20.8 20.1 8.0 4.7 12.0 10.3 6.5 8.1 12.1 4.2 12.6 24.4 8.2 2.8 13.6 3.9 3.6 6.6 6.0 5.8 3.9 2.6 4.7 6.2 5.8 2.4 7.6 2.9 4.1 5.2 2.5 14.1 9.5 7.0 29.0 12.4 12.4 9.4 13.7 13.9 6.3 17.9 42.6 40.8 110.6 103.7 39.3 226.3 94.3 91.0 31.8 59.3 58.9 156.3 306.7 20.9 78.9 50.0 102.5 327.1 14.7 23.0 86.0 142.6 25.3 48.9 37.7 39.7 146.0 28.8 34.5 17.0 36.2 31.8 101.3 12.6 83.5 411.5 37.2 85.6 43.9 43.1 40.3 71.1 166.9 28.7 7.7 84.6 137.0 29.9 64.3 133.5 OBSL1 KIAA0657 ENSG00000124006 "Obscurin like 1" O75147 2 219550729-219571859 "Disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 82.2" "Group enriched" "Detected in many" 4 "Early spermatids: 829.2;Late spermatids: 1255.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.8;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 10 "dendritic cells: 2.7;granulocytes: 6.8" "Cell line enhanced" "Detected in many" "BEWO: 45.0;SK-BR-3: 43.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome NA NA Centrosome "HPA036404: AB_10670437, HPA036405: AB_2675104" "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (3.86e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.27e-3)" "unprognostic (2.89e-2)" "unprognostic (9.89e-2)" "unprognostic (4.22e-3)" "unprognostic (1.25e-1)" "unprognostic (4.21e-3)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (3.62e-2)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.16e-1)" 10.7 26.9 13.4 7.0 11.5 1.2 11.7 18.0 16.2 17.6 8.7 10.3 10.5 3.8 18.2 23.3 7.3 19.9 14.5 30.7 12.8 8.2 19.6 14.5 9.3 3.4 5.5 10.9 82.2 35.6 23.5 16.6 19.3 11.5 15.1 2.3 19.1 25.5 19.1 21.0 14.8 4.8 10.5 8.8 8.2 10.3 15.5 11.5 0.8 34.1 12.4 2.6 10.1 12.1 0.1 2.7 6.8 0.4 0.1 0.2 0.0 9.5 6.4 11.9 24.7 8.2 6.1 45.0 7.2 10.6 9.2 8.5 5.6 14.9 0.0 15.3 9.8 8.9 9.8 9.2 5.4 1.9 0.0 16.1 20.7 6.2 28.3 6.2 0.5 0.1 16.5 4.5 2.1 3.5 16.4 1.0 0.0 8.5 0.2 6.5 23.6 0.0 5.9 28.2 2.7 6.6 10.6 10.4 0.0 16.6 9.0 5.2 17.8 8.2 43.7 16.4 31.4 4.0 17.9 2.4 9.8 10.6 3.0 2.8 0.0 0.0 0.0 5.7 0.0 9.7 6.8 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.8 0.1 0.4 2.7 0.0 0.0 13.4 11.5 18.0 16.2 12.8 8.2 5.5 10.9 11.5 11.5 8.9 14.8 0.0 19.2 7.4 33.3 45.9 25.5 8.1 10.3 50.6 2.0 55.5 44.7 13.5 829.2 12.0 2.0 0.0 10.7 57.4 14.5 10.9 4.6 13.9 6.6 39.7 19.7 10.4 1.0 1255.6 71.4 3.2 13.5 1.0 3.1 79.6 9.7 2.5 69.6 15.4 9.5 12.9 17.5 239.3 51.1 5.8 72.3 0.0 2.3 7.8 OTUD5 "DKFZp761A052, DUBA" ENSG00000068308 "OTU deubiquitinase 5" Q96G74 X 48922028-48958386 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "U-266/70: 187.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017375 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoplasm, Nucleoli fibrillar center" "HPA017375: AB_1854844" "unprognostic (9.73e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.67e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (6.65e-2)" "unprognostic (2.33e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "prognostic favorable (8.20e-4)" "unprognostic (1.32e-1)" "unprognostic (3.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-2)" "unprognostic (5.05e-3)" 23.5 27.5 32.4 26.8 40.9 38.4 21.9 35.0 52.4 21.3 22.9 28.2 23.4 30.5 25.5 26.8 20.5 25.1 20.9 16.6 29.8 31.3 22.6 24.5 25.2 30.8 25.4 29.8 30.0 25.4 29.6 26.8 23.1 29.4 24.0 17.8 20.4 26.9 27.4 24.4 24.5 29.1 27.1 21.4 34.5 22.3 12.7 24.0 34.8 24.5 14.4 27.2 22.1 22.7 7.8 6.3 8.6 5.1 18.6 7.5 3.5 6.2 9.5 4.4 11.0 7.5 6.8 5.2 5.5 6.5 7.0 7.6 4.7 7.0 7.0 3.6 6.9 6.1 7.7 6.7 5.6 6.5 8.2 8.1 5.3 9.6 5.4 6.4 5.0 5.9 7.5 5.2 7.2 4.9 7.7 5.5 5.8 6.7 11.1 4.9 6.3 7.9 10.9 8.0 2.3 7.5 6.3 6.5 9.1 4.9 5.6 4.3 7.6 7.3 4.7 7.3 10.8 6.3 4.6 7.8 4.6 5.8 12.0 4.5 187.1 46.7 6.7 7.0 7.1 3.1 5.2 3.4 7.0 7.0 5.1 5.8 7.8 5.5 6.0 4.8 6.0 5.2 7.5 8.6 18.6 4.7 6.3 7.0 3.5 32.4 40.9 35.0 52.4 29.8 31.3 25.4 29.8 29.4 24.0 8.9 21.1 23.0 19.4 19.7 31.7 8.5 10.2 17.4 17.0 26.2 25.5 11.3 8.3 13.0 1.5 18.5 26.4 0.0 15.9 12.0 16.5 23.0 6.9 22.9 14.5 27.0 46.2 18.4 24.7 1.5 19.2 19.5 25.3 21.6 26.6 16.0 17.8 15.8 22.3 20.3 25.0 12.9 13.3 5.9 10.9 22.3 25.7 30.9 17.4 22.8 OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive 1" O95747 3 38165089-38255488 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Urothelial cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Enhanced Cytosol NA NA 21000000 Cytosol "CAB017181: , HPA008237: AB_1079540" "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (1.79e-2)" "unprognostic (4.55e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (3.53e-3)" "unprognostic (4.05e-2)" "unprognostic (4.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.95e-3)" "unprognostic (1.88e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-1)" "unprognostic (6.99e-3)" 17.6 16.8 9.4 18.3 13.4 24.2 15.9 17.4 14.9 16.8 15.4 9.2 35.7 12.4 14.9 14.7 31.6 11.6 18.9 15.5 11.9 9.0 18.3 17.6 14.6 13.9 13.6 9.3 16.7 12.3 23.7 15.3 21.4 12.3 16.5 16.8 13.0 15.1 23.9 32.6 17.4 21.4 17.0 12.9 15.8 14.0 11.2 13.2 26.2 14.2 24.1 19.6 23.5 19.2 2.3 4.4 10.1 4.8 5.0 4.7 1.6 17.7 8.1 16.3 11.3 11.4 13.2 18.5 15.7 21.6 22.8 24.8 10.5 11.6 19.7 8.0 18.8 9.8 11.1 21.8 16.2 30.1 20.8 8.9 21.5 17.3 11.4 13.6 13.3 13.2 10.4 19.1 21.0 34.1 21.5 14.2 25.5 16.3 11.4 39.0 5.0 25.6 9.6 17.1 11.5 9.7 8.9 13.6 15.2 14.0 13.5 8.5 13.1 17.2 43.6 10.7 18.7 14.3 8.7 12.9 14.3 14.2 21.7 23.2 8.7 10.3 14.5 19.7 16.6 28.5 10.1 2.8 6.1 3.3 4.8 3.5 1.9 4.0 3.1 4.4 2.3 3.0 3.7 5.5 5.0 4.1 2.5 4.7 1.6 9.4 13.4 17.4 14.9 11.9 9.0 13.6 9.3 12.3 13.2 11.9 26.3 13.3 24.0 39.2 11.8 26.6 2.5 12.0 27.3 26.2 19.6 9.4 16.6 25.2 3.1 17.1 28.7 0.0 12.5 15.6 14.9 44.7 15.1 17.8 13.4 20.6 23.2 12.3 32.9 1.4 8.9 28.2 6.8 33.3 18.0 7.6 33.8 24.6 12.0 19.4 5.5 12.9 26.7 12.7 15.0 45.4 27.6 17.5 15.3 110.3 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860694 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 383.4;pancreas: 677.5" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 1160.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" No No 140000000 "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 18.0 34.7 6.3 15.4 8.4 35.0 16.1 6.1 6.5 22.1 40.5 9.0 45.0 42.6 14.7 29.1 40.3 12.8 42.3 20.7 6.3 5.9 27.2 383.4 20.9 29.1 7.9 4.5 14.3 677.5 6.4 23.4 58.5 7.2 22.5 8.5 12.3 251.9 42.5 31.0 24.3 112.8 11.0 5.2 36.7 31.6 9.1 7.2 10.5 29.7 50.7 46.4 16.5 20.5 21.6 71.3 45.8 60.8 38.8 55.9 70.8 58.4 50.9 18.9 60.8 51.0 60.1 44.7 114.3 73.7 49.8 67.5 37.4 51.3 23.6 50.3 73.4 30.1 41.5 20.7 44.7 28.9 15.2 35.1 35.3 53.6 152.0 67.1 111.5 58.5 45.3 30.4 39.9 42.3 64.5 82.1 16.9 25.0 102.0 35.5 53.4 31.9 88.6 14.8 62.0 46.4 26.1 33.8 46.8 38.7 70.7 22.7 25.1 57.0 164.5 59.3 32.6 74.4 131.4 63.7 93.6 46.9 53.1 55.7 73.4 53.1 22.3 123.0 43.0 71.3 45.8 60.8 38.3 53.5 38.7 55.9 21.6 36.4 42.8 43.4 18.7 21.2 31.5 20.0 38.8 27.6 71.3 25.7 70.8 6.3 8.4 6.1 6.5 6.3 5.9 7.9 4.5 7.2 7.2 95.3 135.6 82.0 139.4 106.7 53.8 19.6 234.4 58.9 83.0 106.4 31.4 682.3 34.9 562.2 31.8 104.1 635.2 0.0 930.3 1160.9 218.5 265.2 99.1 768.8 403.4 58.8 191.7 211.1 166.1 51.9 130.9 120.0 129.9 349.9 361.7 113.5 636.3 443.3 105.4 92.7 40.7 155.2 103.8 85.8 107.3 126.5 837.3 139.5 385.8 170.2 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77321707-77474635 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 70.0;brain: 71.4" "Cell type enhanced" "Detected in many" 4 "granulocytes: 126.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 29.3;eosinophil: 45.0;intermediate monocyte: 28.7;myeloid DC: 42.3;neutrophil: 70.0;non-classical monocyte: 30.4" "Group enriched" "Detected in all" 11 "dendritic cells: 42.3;granulocytes: 70.0;monocytes: 30.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 200000 "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 5.4 6.0 30.5 13.8 39.5 22.9 7.8 49.1 71.4 9.8 18.2 8.4 2.3 18.2 9.1 13.3 9.9 9.8 13.2 5.3 19.0 16.9 11.3 6.0 6.9 7.5 12.8 40.6 10.4 9.2 11.8 10.8 11.9 39.2 12.2 20.2 5.4 10.4 8.8 34.0 6.7 18.9 11.6 7.8 11.7 17.1 11.1 6.6 7.6 17.7 3.9 9.4 10.5 10.4 2.7 42.3 70.0 30.4 4.3 2.4 12.2 11.4 7.7 16.8 7.6 6.8 11.5 13.4 13.1 9.4 12.4 14.7 11.0 15.3 10.2 4.8 11.3 16.2 5.9 11.7 13.8 19.7 11.8 9.4 10.8 5.2 0.7 4.5 18.2 16.0 8.5 8.4 14.6 21.7 11.0 2.9 12.0 7.1 18.0 22.6 0.8 11.6 8.4 24.7 47.4 6.6 17.8 21.7 0.4 3.1 9.5 7.2 7.1 7.0 3.0 5.5 17.3 13.4 8.3 0.2 8.3 14.4 44.3 10.9 49.6 25.5 6.8 6.9 12.2 8.9 0.3 29.3 45.0 1.9 28.7 1.5 2.7 1.4 1.8 42.3 1.9 1.3 2.4 70.0 4.3 30.4 3.6 1.1 12.2 30.5 39.5 49.1 71.4 19.0 16.9 12.8 40.6 39.2 6.6 3.0 21.5 16.1 27.9 10.5 48.2 3.1 33.1 41.5 33.0 24.4 7.9 23.0 38.1 26.3 31.5 3.0 46.3 0.0 49.4 46.4 13.1 25.6 126.2 10.9 45.2 1.6 36.2 3.1 43.9 20.0 13.3 71.3 28.7 94.6 47.0 14.0 41.8 55.2 12.4 28.6 6.7 12.9 18.2 25.6 42.1 9.2 79.4 12.2 47.1 27.2 PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007794 Approved Approved Nucleoplasm,Vesicles NA NA 590000 "Nucleoplasm, Vesicles" "CAB007794: AB_562363" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.85e-2)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.36e-4)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.30e-3)" "unprognostic (4.57e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-2)" "unprognostic (3.39e-1)" 28.7 18.9 22.4 27.6 23.5 21.4 56.5 17.4 20.7 19.5 23.0 27.8 17.4 19.0 22.6 19.2 23.4 17.9 20.7 29.0 22.6 22.0 19.5 34.3 35.7 50.2 26.8 13.5 19.9 16.6 30.5 13.0 27.6 22.8 17.7 23.0 12.9 19.6 21.2 34.2 16.3 25.2 23.0 32.1 34.6 18.4 15.9 24.8 44.9 16.9 19.1 31.9 24.1 32.7 6.6 13.7 25.9 12.6 6.6 10.8 7.0 36.0 12.9 18.1 13.3 12.9 17.1 27.0 18.3 15.1 19.9 18.1 30.6 18.5 23.1 52.3 18.4 20.3 18.5 19.2 17.4 30.8 10.4 9.3 34.2 14.9 24.0 26.2 33.2 32.9 13.6 14.3 17.8 37.9 21.1 19.6 25.7 16.4 28.8 19.3 38.0 31.6 17.2 10.8 19.4 19.5 28.9 10.3 20.9 17.4 25.3 10.6 12.1 24.5 17.3 13.8 14.6 60.5 24.1 20.2 16.5 9.2 17.3 26.9 19.6 34.6 56.9 13.7 33.3 15.7 16.5 10.3 24.5 6.3 12.6 8.5 6.4 7.3 7.1 13.7 6.6 5.4 6.3 25.9 6.6 10.8 5.1 10.8 7.0 22.4 23.5 17.4 20.7 22.6 22.0 26.8 13.5 22.8 24.8 74.5 44.7 76.2 49.3 86.5 39.1 56.5 63.7 88.3 47.8 78.5 49.1 41.1 28.2 62.3 49.4 78.8 52.5 0.0 51.3 82.8 47.0 116.6 143.4 125.4 90.3 52.4 43.1 63.3 144.6 51.0 56.4 118.7 32.1 120.0 42.8 58.0 77.2 48.4 42.8 60.3 40.6 38.8 52.3 24.2 41.4 75.4 29.2 71.3 38.3 112.3 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.2;pancreas: 46.5;pituitary gland: 37.2" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 81.5;Leydig cells: 31.7;Peritubular cells: 76.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 4.3" "Lineage enriched" "Detected in single" 7 "T-cells: 4.3" "Cell line enhanced" "Detected in some" "EFO-21: 9.8;HAP1: 8.8;HDLM-2: 11.0;NTERA-2: 8.6;SCLC-21H: 11.2;SH-SY5Y: 7.0;U-2197: 6.8;U-251 MG: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA Vesicles "HPA044791: , HPA060219: AB_2684223" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 2.0 6.8 17.6 2.5 17.5 1.0 6.4 1.8 24.6 3.7 1.6 0.9 9.1 1.0 6.8 7.6 1.7 3.7 2.6 1.2 26.2 20.8 1.6 1.1 1.8 2.5 7.9 21.9 7.9 46.5 0.9 37.2 1.6 12.9 4.8 1.7 1.4 3.0 7.1 2.4 2.0 1.4 6.1 5.8 2.9 3.0 3.6 1.9 0.0 7.7 0.0 1.7 2.0 1.5 0.1 0.1 0.6 0.1 0.2 4.3 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 9.8 1.0 1.4 0.0 8.8 0.5 1.2 11.0 0.3 0.0 1.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 2.0 5.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 8.6 0.0 1.9 0.1 4.0 0.0 0.8 0.0 11.2 7.0 0.0 0.4 0.0 6.2 0.0 0.0 0.0 0.6 4.3 6.8 11.7 0.0 0.1 0.1 1.2 0.0 0.1 0.6 0.1 0.1 0.1 0.0 4.3 0.0 0.7 0.4 0.0 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.3 0.0 17.6 17.5 1.8 18.5 26.2 20.8 7.9 21.9 12.9 1.9 3.0 1.4 0.0 14.1 0.2 81.5 0.8 12.7 0.0 1.2 0.0 0.0 0.3 0.0 3.0 3.4 2.4 0.0 0.0 11.6 0.3 5.8 1.3 1.1 0.0 0.2 6.4 3.5 0.6 0.3 4.7 31.7 2.0 0.0 1.0 0.0 19.0 7.3 0.0 76.4 0.5 5.5 0.0 0.4 1.1 0.6 1.0 5.6 2.2 0.0 0.9 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 45.4;MCF7: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 6.8 11.1 11.0 12.7 12.3 4.8 11.9 13.7 12.4 17.3 19.6 13.7 19.9 26.0 12.2 17.3 20.1 15.3 16.5 8.1 10.9 8.1 19.4 17.0 18.7 5.4 13.7 7.7 13.8 29.6 11.2 17.0 23.0 10.3 29.6 8.1 19.7 40.9 18.5 10.3 18.6 25.1 9.0 8.3 7.9 18.6 22.3 12.5 8.8 15.2 10.1 14.7 11.5 15.0 2.8 3.4 4.2 2.5 3.6 4.5 1.9 17.9 45.4 6.8 10.3 2.1 2.3 20.5 8.6 3.5 5.8 5.9 29.7 15.3 4.1 13.1 5.4 7.6 6.6 3.7 6.8 2.2 10.9 10.4 4.8 8.3 14.4 3.4 4.9 7.1 2.7 3.0 5.4 3.9 3.8 7.5 6.3 9.7 3.2 3.4 50.0 5.2 5.4 12.3 15.9 10.9 5.3 5.3 3.1 5.6 19.8 21.7 15.0 8.7 39.0 9.7 3.7 17.3 8.2 12.5 9.9 17.0 11.3 15.3 3.7 3.5 3.4 12.1 2.9 11.8 1.0 2.5 4.2 2.6 1.4 3.6 2.2 2.9 4.5 3.4 2.8 2.2 2.2 2.1 3.6 2.1 2.9 3.0 1.9 11.0 12.3 13.7 12.4 10.9 8.1 13.7 7.7 10.3 12.5 0.0 1.0 0.5 15.0 12.8 14.8 1.2 20.4 6.7 0.0 17.4 23.6 35.6 26.6 18.7 2.7 15.8 35.5 0.0 17.2 46.7 10.8 17.8 5.7 10.5 8.3 20.6 43.0 12.3 5.6 4.9 10.9 2.5 6.8 14.4 30.6 14.1 16.5 40.3 9.9 10.6 13.1 0.0 7.2 5.7 17.7 16.4 54.7 8.7 29.9 20.6 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537389-9839041 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 30.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "SCLC-21H: 10.2;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.5 5.2 5.7 0.6 11.7 0.5 1.6 30.3 19.6 0.8 0.6 0.8 0.0 0.7 1.0 2.2 1.0 0.7 3.4 0.6 4.0 3.3 1.0 2.3 0.7 0.6 1.6 8.8 0.6 3.5 0.5 2.0 0.6 5.3 1.6 0.6 0.6 1.2 1.6 0.6 1.6 0.6 0.6 1.2 0.6 1.2 1.0 1.7 0.0 0.6 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 3.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 5.7 11.7 30.3 13.6 4.0 3.3 1.6 8.8 5.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40238759-40277487 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 22.2" "Cell type enhanced" "Detected in many" 11 "Cytotrophoblasts: 38.8;Suprabasal keratinocytes: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 14.8;HaCaT: 23.0;hTCEpi: 14.1;SK-BR-3: 7.8" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.3 5.3 14.7 0.8 18.4 0.8 2.3 11.3 20.1 3.0 1.3 1.6 2.5 1.4 1.0 1.1 15.8 4.3 1.4 7.9 11.6 5.2 3.4 0.4 2.6 1.0 3.0 10.9 0.6 7.4 12.9 6.4 8.1 2.1 3.6 1.2 0.3 3.4 7.5 3.5 22.2 1.4 0.8 1.2 1.0 3.6 12.8 2.2 0.0 7.4 8.5 5.1 3.0 5.1 1.4 0.7 2.9 0.7 2.0 5.5 1.2 2.7 0.0 0.2 0.1 0.0 0.0 4.4 0.0 0.1 0.6 0.4 14.8 2.0 0.1 2.4 0.0 0.9 23.0 3.3 4.9 0.2 0.1 0.7 0.0 1.9 0.1 0.0 0.1 0.3 0.0 14.1 0.2 3.3 0.2 0.0 3.9 1.1 0.2 0.0 3.2 0.0 0.3 0.4 2.7 2.0 0.2 0.1 1.8 1.1 6.0 5.4 1.3 1.9 7.8 0.2 1.3 0.9 7.2 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.5 0.4 0.1 2.1 0.7 2.9 5.5 0.3 2.1 1.4 0.5 4.2 0.7 0.5 0.3 1.2 1.3 2.0 0.2 0.5 0.1 1.2 14.7 18.4 11.3 20.1 11.6 5.2 3.0 10.9 2.1 2.2 0.0 3.4 0.0 6.8 8.8 3.9 0.0 7.6 4.0 4.5 5.2 0.0 38.8 11.6 4.0 5.9 0.0 0.0 0.0 3.7 1.2 0.6 4.0 0.0 0.0 3.5 0.0 4.7 0.0 0.3 4.5 1.7 0.3 1.7 0.0 0.8 1.4 2.7 0.0 1.8 0.0 0.0 0.0 0.1 1.6 1.5 16.7 7.6 1.3 1.9 6.8 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 304.2" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 852.6;Intestinal endocrine cells: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 75.3;fHDF/TERT166: 96.5;hTERT-RPE1: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA 59000000 "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 16.5 24.5 8.2 6.5 16.4 0.8 17.3 6.6 16.5 74.9 14.0 5.4 9.5 5.8 21.3 83.8 11.7 10.6 11.5 304.2 8.8 23.5 13.7 2.1 13.2 5.8 10.0 7.6 17.0 16.4 49.5 18.3 26.3 15.5 13.4 9.5 8.7 53.8 29.4 22.0 8.5 8.5 18.5 4.8 8.9 17.2 7.2 4.6 1.8 21.7 13.2 7.3 15.8 15.3 0.5 2.0 10.1 5.3 16.2 14.1 6.3 14.7 2.2 27.1 12.0 75.3 45.1 10.8 41.8 62.6 12.4 37.8 7.1 19.5 0.0 9.0 96.5 17.5 5.0 1.5 18.4 34.3 1.8 6.1 3.0 8.8 2.3 11.4 0.9 3.3 24.6 7.9 9.1 6.9 78.8 25.5 1.2 0.1 2.0 35.1 3.0 0.0 0.4 4.8 2.6 8.1 1.1 15.1 8.1 47.8 1.7 12.8 8.9 17.8 1.1 10.9 16.6 4.6 0.9 19.6 39.4 10.2 18.4 12.4 4.6 1.1 0.0 45.2 4.1 33.9 1.9 5.3 0.1 14.1 0.9 10.0 0.5 8.5 10.4 2.0 0.3 2.9 4.8 10.1 16.2 1.9 1.1 12.1 6.3 8.2 16.4 6.6 16.5 8.8 23.5 10.0 7.6 15.5 4.6 50.6 28.7 3.7 10.4 25.0 10.9 852.6 0.0 10.7 27.3 57.6 2.0 0.7 6.6 11.6 5.0 54.1 6.8 0.0 18.6 37.1 102.7 20.4 9.2 2.4 5.5 7.9 308.8 70.0 12.0 4.7 55.8 6.7 35.4 5.4 12.6 13.0 34.7 2.9 55.2 41.6 2.8 19.4 47.4 1.6 2.1 20.7 5.6 15.3 6.6 13.1 PAN2 "hPAN2, KIAA0710, USP52" ENSG00000135473 "PAN2 poly(A) specific ribonuclease subunit" Q504Q3 12 56316223-56334053 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (9.10e-3)" "unprognostic (1.03e-1)" "unprognostic (7.28e-2)" "unprognostic (7.35e-3)" "unprognostic (3.80e-1)" "unprognostic (1.74e-3)" "unprognostic (4.23e-3)" "prognostic unfavorable (2.77e-4)" "unprognostic (4.19e-1)" "unprognostic (3.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" 8.1 13.4 12.8 7.1 17.7 7.4 9.9 21.7 17.6 9.6 9.5 16.1 16.4 11.0 11.2 17.6 7.4 11.3 7.8 9.8 13.9 5.1 9.7 17.6 8.7 9.0 19.7 7.0 17.8 12.9 24.3 30.7 9.2 14.6 9.1 9.6 12.6 10.0 14.1 9.1 9.4 10.7 8.8 16.4 10.6 10.5 18.2 19.4 15.3 20.2 4.8 11.0 11.0 9.2 3.1 7.6 3.9 8.1 3.8 5.2 3.4 2.8 4.4 10.8 3.5 9.5 10.8 7.1 2.2 3.0 5.0 2.3 2.6 5.7 7.9 8.6 4.3 2.7 6.0 12.7 8.4 2.8 3.5 6.2 10.1 4.2 2.5 8.4 2.2 5.4 10.1 11.4 5.3 15.5 13.2 3.7 16.8 6.8 19.9 2.9 6.2 7.5 5.6 3.6 4.8 2.9 6.5 7.7 14.2 4.9 2.3 8.6 7.7 4.2 5.5 5.4 12.6 7.1 4.4 1.6 5.2 5.1 2.3 2.0 16.8 6.6 5.2 6.1 4.7 4.2 3.9 5.8 2.3 2.4 8.1 3.7 3.1 1.9 3.5 7.6 2.7 4.1 5.2 0.4 3.8 3.8 2.9 3.0 3.4 12.8 17.7 21.7 17.6 13.9 5.1 19.7 7.0 14.6 19.4 8.9 17.1 4.7 4.8 4.5 25.5 9.0 5.1 16.0 10.3 5.2 25.5 6.5 1.7 2.4 1.2 6.0 5.5 0.0 1.8 4.1 5.6 3.7 5.8 15.3 4.7 14.3 13.8 12.9 5.4 2.1 10.3 6.3 1.7 2.8 9.6 7.2 3.3 8.2 6.0 2.8 16.3 6.5 3.1 19.1 6.1 3.3 4.2 5.7 8.5 2.7 PARP1 "ADPRT, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360691-226408079 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Cytotrophoblasts: 400.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm,Nucleoli NA NA 39000 Nucleoplasm Nucleoli "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: AB_2665732, CAB075727: AB_2665733, HPA045168: AB_2679240" "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" 17.3 16.6 31.2 35.7 31.2 14.3 15.3 21.1 29.2 14.3 21.8 37.4 10.3 15.0 18.2 13.0 18.1 15.0 10.8 24.2 27.8 21.9 13.4 24.8 14.1 56.3 40.7 21.8 14.6 28.1 62.6 22.9 28.7 30.4 22.0 19.2 16.3 17.0 24.7 47.3 11.7 19.6 25.5 49.1 32.7 15.9 22.5 34.8 29.5 14.5 16.5 70.2 19.9 13.7 53.0 16.5 9.0 17.5 11.1 21.8 11.5 28.9 15.5 43.2 30.6 11.3 9.4 24.6 19.2 17.1 26.1 21.5 24.7 14.2 84.4 28.7 11.6 11.5 21.8 59.4 18.8 23.1 35.4 82.9 32.6 20.7 16.1 6.8 54.2 15.8 9.2 7.5 21.0 14.9 7.3 20.3 19.6 51.9 43.1 13.5 13.8 17.3 19.6 79.5 40.9 30.8 52.5 74.0 78.0 12.2 20.7 43.5 38.1 25.0 28.0 15.7 31.8 23.5 34.0 15.4 13.9 23.0 18.7 35.9 17.6 29.4 72.5 11.6 18.3 31.1 9.0 6.7 6.9 18.3 11.3 21.6 46.8 19.4 18.0 14.3 53.0 15.2 16.4 1.0 11.1 17.5 16.5 21.8 11.5 31.2 31.2 21.1 28.4 27.8 21.9 40.7 21.8 30.4 34.8 50.6 68.3 130.2 75.6 64.2 94.4 106.4 43.3 75.0 97.8 54.1 133.5 400.4 61.3 77.0 28.3 54.0 16.8 23.3 91.9 75.6 55.5 70.8 116.9 65.7 117.1 85.8 72.1 31.9 42.2 16.3 37.2 45.7 59.1 93.8 46.5 78.6 54.3 24.6 32.9 36.1 102.8 45.3 47.4 92.8 211.4 42.0 115.1 74.0 57.9 42.9 PARP10 FLJ14464 ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 16.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA028122, HPA052427" Approved Supported "Nucleoli rim,Golgi apparatus,Cytosol" No No "Nucleoli rim" "Golgi apparatus, Cytosol" "HPA028122: AB_10601979, HPA052427: AB_2681828" "unprognostic (9.80e-3)" "unprognostic (5.89e-2)" "unprognostic (2.63e-3)" "unprognostic (9.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (4.69e-3)" "unprognostic (1.09e-3)" "unprognostic (4.17e-2)" "unprognostic (8.69e-2)" "unprognostic (5.30e-3)" 14.2 18.8 8.8 27.4 9.5 15.7 18.6 5.3 8.7 14.4 16.5 9.3 20.7 20.5 20.3 18.3 15.8 18.0 21.8 6.4 8.9 4.1 20.5 19.1 21.4 23.6 10.4 6.8 22.4 15.3 9.3 14.2 10.4 9.2 17.7 3.8 12.7 27.7 14.9 12.5 14.3 21.8 9.6 8.9 31.1 13.1 15.8 9.8 27.8 15.4 10.4 21.6 8.8 12.9 2.4 16.4 3.2 2.8 1.9 4.6 2.4 8.4 0.8 0.6 1.5 4.2 3.8 4.6 1.4 1.8 9.5 10.7 0.4 14.8 10.5 20.1 4.5 10.9 3.2 0.2 5.0 0.4 23.6 0.0 11.6 4.9 5.3 4.1 4.5 14.0 2.4 5.0 4.7 1.9 1.0 1.4 15.1 0.2 8.4 1.8 10.3 15.7 7.9 0.5 0.1 6.8 14.7 1.7 14.1 3.9 10.7 0.5 0.5 9.8 1.0 18.6 0.2 11.0 6.8 6.5 4.9 7.4 8.2 5.2 14.3 8.4 2.4 7.1 15.3 2.6 0.0 1.9 3.2 4.6 2.8 3.0 1.2 2.2 3.7 2.3 2.4 1.6 2.3 1.1 1.9 2.7 16.4 1.6 2.4 8.8 9.5 5.3 8.7 8.9 4.1 10.4 6.8 9.2 9.8 3.0 6.9 15.7 7.9 6.8 5.9 2.0 7.6 1.4 1.2 8.7 13.7 1.9 1.7 7.6 4.3 7.1 15.1 0.0 4.9 3.0 6.7 4.0 19.5 19.5 10.9 0.0 18.4 11.1 13.9 5.9 14.7 9.2 6.8 30.7 13.6 11.1 6.5 11.2 10.6 20.3 20.2 6.5 8.9 10.0 1.3 4.1 1.1 20.8 12.7 3.3 PARP11 C12orf6 ENSG00000111224 "Poly(ADP-ribose) polymerase family member 11" Q9NR21 12 3791047-3873448 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA transport, Protein transport, Spermatogenesis, Translocation, Transport" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026895 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026895: AB_1854980" "unprognostic (9.58e-2)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.53e-1)" "unprognostic (2.61e-1)" "unprognostic (3.58e-2)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (2.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.81e-2)" "unprognostic (2.87e-2)" 7.1 14.5 11.2 8.6 9.2 3.7 8.3 11.0 9.1 6.4 5.4 5.6 4.8 4.9 10.2 7.5 5.0 6.3 5.6 5.1 6.1 5.7 5.7 5.7 6.3 12.8 5.0 5.7 13.1 6.6 10.0 10.4 4.1 7.6 12.0 5.7 7.2 6.6 6.0 4.1 3.9 6.5 7.2 6.1 9.2 4.2 12.8 5.6 16.9 12.3 2.7 12.1 8.3 5.8 10.7 10.2 18.3 10.2 8.2 12.5 7.1 2.3 1.9 12.8 2.0 4.1 6.5 3.6 2.8 4.8 5.0 5.0 7.3 1.8 7.0 1.8 6.2 6.3 2.0 4.2 4.2 8.1 14.1 4.2 10.0 0.0 5.4 4.6 6.7 3.8 5.2 3.3 3.9 11.1 0.0 3.7 13.7 2.6 5.7 7.0 3.3 3.5 2.6 4.7 2.4 0.3 7.1 8.7 1.6 2.3 5.3 0.8 2.9 2.8 2.4 3.6 14.6 0.4 6.1 7.2 4.3 4.3 6.6 3.8 2.7 5.9 9.8 4.1 3.7 1.1 18.3 10.2 10.2 9.2 8.5 12.5 10.7 10.2 6.7 10.2 10.1 11.7 9.4 10.2 8.2 6.4 8.9 4.3 7.1 11.2 9.2 11.0 9.1 6.1 5.7 5.0 5.7 7.6 5.6 8.9 7.4 11.8 4.3 1.6 11.1 3.2 2.5 6.7 2.3 1.8 2.0 3.0 0.0 3.1 60.8 4.5 2.1 0.0 2.6 1.5 4.6 8.0 14.9 3.4 6.2 3.2 3.5 8.0 9.1 25.5 9.8 6.9 1.7 3.6 3.7 6.2 2.9 4.2 8.1 3.3 6.9 6.5 5.1 7.5 8.7 1.6 2.2 10.2 4.3 3.4 PARP12 "FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023744-140063721 "Enzymes, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003584, HPA063872" Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA003584: AB_1079568, HPA063872: AB_2685139" "unprognostic (1.46e-3)" "unprognostic (2.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "unprognostic (6.74e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (2.30e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (7.51e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (4.12e-7)" "unprognostic (3.31e-2)" "unprognostic (2.76e-1)" "unprognostic (1.75e-2)" "unprognostic (6.01e-2)" 3.1 1.8 1.0 3.7 0.9 6.1 2.5 0.1 0.7 2.1 2.2 4.2 2.8 4.2 2.1 2.5 3.1 1.7 1.0 1.0 3.1 3.0 5.2 3.8 1.0 3.2 2.7 2.5 3.3 3.4 2.8 3.9 4.3 1.4 0.9 8.6 4.4 1.5 1.3 6.0 2.3 5.7 3.2 2.7 1.9 3.1 1.0 1.3 3.4 2.0 2.3 3.3 2.4 3.7 2.3 0.0 0.4 1.1 0.5 3.9 0.6 0.5 4.7 8.0 2.7 3.5 1.7 2.8 1.1 4.8 3.8 1.5 4.4 1.3 4.7 4.7 1.4 1.4 1.8 2.1 0.4 1.4 1.6 2.6 2.0 4.3 3.3 5.0 2.7 4.1 2.3 0.0 2.9 4.5 12.1 0.2 1.8 7.0 2.0 0.0 0.0 2.1 2.3 1.4 0.0 2.4 1.1 3.5 0.6 0.6 0.9 9.6 1.5 2.2 0.5 3.5 0.1 0.1 0.4 0.9 6.0 0.8 0.7 2.0 2.2 2.9 1.7 1.1 0.3 1.9 2.9 1.3 1.0 0.6 1.9 3.4 2.3 1.9 0.7 3.3 2.4 6.0 11.7 6.0 6.5 5.8 3.0 4.2 10.2 5.3 5.7 10.4 2.0 4.5 1.7 10.9 0.6 11.7 32.5 0.0 22.8 16.4 5.3 10.8 19.6 9.6 21.5 0.0 23.1 6.2 10.2 0.4 6.6 13.9 6.8 12.6 13.2 2.6 27.2 25.9 6.7 5.6 2.2 0.0 5.9 28.7 11.9 8.7 1.7 8.7 8.0 9.2 PARP14 "KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680618-122730840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 229.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 29.6;BJ hTERT+ SV40 Large T+ RasG12V: 45.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol NA NA Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 21.6 10.3 5.6 15.8 7.2 11.7 9.3 2.3 6.0 11.6 13.3 5.9 6.4 11.4 10.6 12.7 11.7 7.2 10.0 6.5 5.2 4.8 13.7 21.5 26.0 16.7 7.3 5.2 10.0 6.7 7.2 6.8 17.5 6.3 12.3 6.7 7.5 8.5 5.5 5.2 5.7 22.3 11.9 6.8 29.7 7.6 4.6 4.9 18.7 20.4 6.4 18.9 12.8 12.4 15.9 4.2 20.8 10.5 7.4 7.0 2.8 5.9 5.0 3.2 3.4 4.5 10.7 0.0 2.3 15.6 29.6 45.6 2.6 11.9 0.0 9.8 5.2 16.6 4.6 4.6 4.8 6.0 9.1 0.5 5.5 2.3 4.0 10.9 2.4 2.7 6.4 2.4 5.1 2.0 7.2 12.8 4.9 2.6 8.9 1.0 3.1 9.1 1.6 0.4 0.9 4.3 12.8 3.2 1.6 7.2 6.2 0.2 0.0 6.0 1.3 6.7 0.4 2.2 4.3 8.6 1.6 3.9 0.9 2.1 3.5 0.6 1.0 4.8 5.7 2.8 8.3 8.2 4.0 6.9 10.5 6.0 10.2 3.8 4.5 4.2 15.9 3.2 3.4 20.8 7.4 9.3 0.6 7.0 2.8 5.6 7.2 2.3 6.0 5.2 4.8 7.3 5.2 6.3 4.9 229.3 87.3 41.0 15.2 14.9 1.1 10.1 30.6 52.2 84.2 24.4 3.9 12.0 3.3 28.1 0.3 61.9 21.0 0.0 35.6 24.3 19.7 23.9 30.2 29.6 32.4 0.0 10.3 67.5 50.6 0.2 25.9 50.6 15.1 94.6 14.3 18.7 33.8 17.5 16.3 7.0 0.8 12.9 18.4 1.6 1.1 9.3 4.0 27.4 11.0 21.3 PARP15 "FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577602-122639047 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.9;lymphoid tissue: 40.4" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 17.9;Alveolar cells type 2: 12.8;B-cells: 22.9;Ciliated cells: 18.7;granulocytes: 18.5;Hofbauer cells: 6.6;monocytes: 6.4;T-cells: 12.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 9.3;MAIT T-cell: 6.5;memory B-cell: 11.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 6.4;naive B-cell: 11.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 5.9;NK-cell: 5.2;T-reg: 4.5" "Group enriched" "Detected in many" 6 "B-cells: 11.9;NK-cells: 5.2;T-cells: 9.3" "Cell line enhanced" "Detected in some" "HEL: 10.6;JURKAT: 6.6;REH: 4.9;THP-1: 5.1;TIME: 12.6" "Not detected" "Not detected" HPA035757 Approved Mitochondria "Intracellular and membrane" NA NA Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 2.4 0.9 0.5 24.5 0.4 9.8 1.3 0.3 0.8 1.2 2.8 1.2 0.5 1.0 1.5 2.3 1.9 1.4 2.8 1.5 0.6 0.5 1.5 1.9 5.6 20.3 0.6 0.6 1.1 2.7 0.0 1.0 1.0 0.6 1.3 2.1 1.8 5.5 0.2 2.6 0.7 22.9 0.9 0.9 40.4 1.7 1.7 0.4 9.4 1.9 1.7 34.8 3.6 1.2 11.9 1.2 1.3 0.6 5.2 9.3 2.7 0.6 0.2 0.5 0.5 0.2 0.3 0.6 0.3 0.2 0.1 0.1 0.3 1.0 0.8 0.6 0.2 0.3 0.6 0.1 0.0 0.0 1.9 0.2 10.6 0.8 0.5 0.2 0.7 0.5 2.2 0.1 0.4 0.2 0.4 2.4 6.6 0.3 2.1 0.0 0.5 3.2 0.7 0.7 0.2 0.3 4.9 0.4 0.6 0.0 1.0 0.8 0.5 0.3 0.2 0.3 0.6 0.8 5.1 12.6 0.4 1.1 0.5 0.4 1.0 0.7 2.4 0.7 0.3 0.2 1.3 0.2 0.1 9.3 0.5 6.5 11.2 5.0 6.4 0.9 11.9 4.3 5.9 0.7 5.2 0.6 1.2 4.5 2.7 0.5 0.4 0.3 0.8 0.6 0.5 0.6 0.6 0.6 0.4 17.9 12.8 22.9 0.0 0.5 0.0 0.4 0.0 18.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 18.5 0.5 6.6 0.0 0.0 2.5 3.5 0.0 0.0 3.2 1.7 6.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.2 12.9 0.0 0.0 PARP16 "C15orf30, FLJ20509, FLJ25281, pART15" ENSG00000138617 "Poly(ADP-ribose) polymerase family member 16" Q8N5Y8 15 65234460-65300618 "Enzymes, Predicted membrane proteins" "Unfolded protein response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Rod photoreceptor cells: 31.3;Spermatogonia: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017081 Approved NA NA "HPA017081: AB_10963218" "unprognostic (1.17e-2)" "unprognostic (6.51e-3)" "unprognostic (2.82e-2)" "unprognostic (6.37e-2)" "unprognostic (7.38e-2)" "unprognostic (2.88e-2)" "unprognostic (3.05e-2)" "unprognostic (6.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.78e-1)" "unprognostic (3.41e-3)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (9.61e-2)" 8.9 14.2 12.0 13.1 11.6 8.0 20.4 32.2 17.7 18.6 12.8 5.6 11.9 9.3 13.1 8.5 10.5 12.0 8.7 7.2 9.7 5.3 9.0 18.1 11.5 14.0 11.5 6.2 17.6 11.3 12.7 8.5 9.2 9.1 11.5 10.4 7.5 10.3 21.4 5.4 10.8 9.7 17.7 8.0 9.3 11.0 7.6 12.0 15.1 9.5 6.3 12.4 14.0 25.6 10.1 4.4 14.1 5.3 10.3 14.2 6.0 3.7 3.8 4.2 6.6 3.5 3.6 1.9 1.7 4.6 4.8 5.0 3.1 3.4 12.1 4.8 2.1 10.3 6.1 19.6 2.4 3.6 4.4 7.8 2.0 4.1 4.3 6.5 5.5 3.8 4.2 4.0 1.2 4.9 7.1 4.4 11.6 5.0 4.6 4.1 4.5 11.4 5.9 2.0 19.3 5.2 21.1 7.7 9.1 3.4 3.4 7.3 4.9 5.3 5.1 4.3 3.5 6.0 5.0 1.8 5.7 4.3 3.2 2.6 8.6 10.1 15.8 4.7 8.2 2.6 14.1 3.3 10.0 11.6 5.3 12.9 7.8 11.2 11.8 4.4 10.1 14.2 10.5 13.0 10.3 5.2 3.9 9.2 6.0 12.0 11.6 32.2 17.7 9.7 5.3 11.5 6.2 9.1 12.0 3.0 1.9 6.6 4.9 4.6 10.8 3.9 7.6 4.0 3.4 3.5 0.0 10.7 0.0 5.2 0.7 3.5 4.0 0.0 7.9 4.2 5.6 2.6 0.0 5.1 3.4 3.2 1.7 1.3 1.8 1.8 9.2 1.8 3.3 4.6 5.2 6.2 3.7 3.4 7.4 3.3 31.3 6.5 4.7 1.6 26.2 3.8 4.6 5.7 6.0 2.4 PARP2 ADPRTL2 ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343582-20357905 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052003 Approved Supported Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA052003: AB_2681689" "unprognostic (3.93e-1)" "unprognostic (7.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (3.37e-3)" "unprognostic (2.83e-1)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-2)" 11.5 16.6 23.6 8.9 28.5 20.9 15.2 36.7 31.3 12.0 11.7 16.8 9.3 11.2 18.8 16.8 10.7 14.7 8.9 14.0 19.2 17.8 14.0 15.0 12.0 11.8 16.6 30.8 20.2 11.8 11.6 14.6 11.3 22.1 11.3 12.9 10.8 10.5 12.9 25.9 15.1 10.8 14.6 13.9 11.4 11.6 20.4 17.4 6.0 11.7 13.9 15.2 9.3 10.4 6.7 5.6 1.8 5.0 6.9 12.3 4.9 20.3 14.9 23.0 17.2 7.6 7.3 16.7 22.7 12.4 28.9 35.8 14.1 19.5 15.1 10.3 7.1 25.8 19.2 30.6 10.4 34.2 12.1 14.9 13.8 18.1 23.5 6.8 28.6 7.9 5.0 8.9 18.0 19.9 8.0 14.8 18.5 14.6 20.7 19.8 12.6 14.6 12.3 12.6 23.2 23.3 18.3 31.3 9.8 11.5 10.6 16.0 11.0 25.3 14.1 6.6 15.3 13.0 9.7 10.1 17.6 26.7 12.1 18.4 19.4 24.7 20.1 7.3 12.7 19.5 1.8 5.0 0.5 9.5 4.5 12.3 6.7 8.9 8.3 5.4 4.6 9.6 9.3 0.1 6.9 2.5 5.6 5.2 4.9 23.6 28.5 36.7 31.3 19.2 17.8 16.6 30.8 22.1 17.4 23.8 6.2 10.4 9.3 5.8 26.8 12.3 5.1 36.1 21.6 7.0 11.8 19.1 6.6 10.5 7.3 10.0 3.4 23.3 7.7 17.9 8.4 3.7 8.1 9.6 10.2 28.6 4.6 6.2 4.9 7.3 10.6 6.4 8.5 4.6 4.2 21.9 8.0 5.5 15.9 5.6 21.7 6.5 9.5 17.7 33.3 4.3 12.5 4.4 5.2 4.6 PARP3 "ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: AB_2685881" "prognostic favorable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favorable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" 15.2 29.2 11.2 14.6 17.1 2.8 13.6 5.7 18.8 7.5 17.3 10.6 14.3 26.9 10.3 14.1 10.8 12.1 16.2 12.4 11.6 12.3 17.3 22.3 13.3 9.7 12.0 14.2 8.2 3.9 34.2 9.8 6.2 12.2 12.1 10.7 13.2 14.0 18.1 14.6 6.1 26.3 18.9 8.7 12.8 15.8 4.5 10.2 2.9 17.0 9.6 10.3 15.1 8.9 9.0 2.9 1.7 4.1 6.6 4.9 2.3 5.9 3.3 0.9 9.0 8.7 16.5 2.5 9.8 15.8 12.1 13.6 1.9 15.8 8.1 2.6 16.1 7.0 0.9 2.5 8.8 5.9 19.9 0.6 4.1 6.7 6.3 9.4 2.5 5.7 13.0 5.5 7.7 5.2 18.6 6.0 5.1 1.7 7.7 9.3 1.5 2.2 6.3 1.2 2.0 9.5 3.5 1.5 7.0 7.4 6.5 1.0 3.4 9.9 2.8 5.2 0.7 3.4 2.8 13.6 24.4 5.1 3.6 5.9 11.8 14.3 3.5 15.7 7.4 7.6 0.0 2.6 1.7 3.6 4.1 3.4 9.0 4.2 2.8 2.9 4.3 4.9 4.9 0.1 6.6 2.0 1.2 4.3 2.3 11.2 17.1 5.7 18.8 11.6 12.3 12.0 14.2 12.2 10.2 6.0 10.6 10.1 10.0 2.4 1.7 5.9 12.7 9.4 7.9 0.0 0.0 0.4 6.6 8.8 5.9 3.0 15.8 0.0 5.7 0.3 4.5 3.4 4.6 8.5 3.4 0.0 2.9 1.8 2.2 8.4 4.4 2.9 6.8 6.4 11.0 4.0 7.9 3.5 1.4 16.1 2.1 6.5 6.2 3.2 1.8 1.3 0.5 5.3 11.2 6.4 PARP4 "ADPRTL1, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420926-24512810 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Ciliated cells: 83.0;granulocytes: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011739 Approved Supported Cytosol Yes No Cytosol "HPA011739: AB_1854986" "unprognostic (1.61e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-2)" "unprognostic (4.35e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (4.12e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.21e-5)" "unprognostic (3.23e-2)" "unprognostic (1.71e-1)" "unprognostic (3.80e-2)" "unprognostic (2.84e-3)" 25.3 24.7 6.6 16.7 12.9 11.6 14.6 2.3 7.0 17.8 39.4 16.7 21.6 22.9 19.1 11.2 22.2 14.9 23.8 11.3 7.9 5.6 28.8 17.3 17.8 16.5 14.6 4.4 15.9 15.5 11.2 12.6 14.8 12.5 16.1 24.1 14.0 17.7 30.9 6.5 10.2 49.9 15.5 20.5 28.4 20.4 7.0 12.1 28.8 18.2 11.3 26.2 23.3 13.2 9.0 16.4 26.1 18.6 11.8 12.9 10.6 14.6 13.1 6.4 11.6 17.8 25.4 5.4 17.1 22.4 15.0 13.4 5.3 38.2 11.0 17.1 15.5 16.6 17.1 9.6 17.3 12.3 25.1 6.7 15.7 12.2 12.3 10.2 20.1 15.6 14.6 5.8 12.4 6.6 29.4 24.6 8.6 4.4 4.9 17.7 6.8 12.6 9.7 7.3 34.7 16.2 12.0 12.1 15.4 27.9 30.2 5.9 7.5 12.5 5.0 11.8 8.8 2.5 16.6 34.8 6.8 7.1 8.7 17.4 5.6 6.4 14.5 12.4 10.6 14.8 25.2 12.4 26.1 12.9 15.3 12.9 9.0 10.8 12.8 16.4 5.1 8.1 9.6 14.3 11.8 18.6 6.2 12.7 10.6 6.6 12.9 2.3 7.0 7.9 5.6 14.6 4.4 12.5 12.1 47.6 43.8 12.3 5.6 2.5 6.0 15.5 20.4 83.0 64.8 24.4 2.0 4.6 5.0 20.5 3.5 18.8 54.7 0.0 19.4 7.7 6.9 8.6 92.8 12.9 15.7 1.6 4.7 36.2 23.1 3.1 10.9 25.1 8.5 31.5 26.9 7.0 25.8 48.9 7.8 15.6 6.9 6.5 6.2 2.8 7.2 3.3 1.6 15.2 26.0 14.8 PARP6 pART17 ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Late spermatids: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" Yes No "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favorable (3.17e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavorable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 13.7 16.6 28.0 12.8 32.4 25.1 26.5 46.6 41.2 15.5 16.2 16.9 18.2 14.1 23.3 23.8 14.0 17.0 20.2 18.4 26.1 22.4 14.3 9.0 15.7 16.8 19.9 21.8 26.3 20.9 20.6 30.8 17.0 19.4 19.3 14.3 14.5 21.3 18.8 23.9 20.3 14.4 19.6 14.2 18.2 18.2 25.1 15.8 9.6 21.7 12.5 15.8 16.3 15.8 4.1 4.0 12.1 5.3 4.3 4.3 2.9 7.3 13.2 13.9 18.1 15.0 12.5 11.3 6.3 9.5 10.4 15.4 8.7 13.3 10.0 3.9 9.5 15.3 9.6 15.3 8.5 6.0 11.9 13.8 14.6 23.1 0.1 12.5 7.5 14.0 16.0 21.0 9.7 26.8 16.4 6.9 16.8 7.4 11.6 8.3 13.3 6.4 13.2 6.4 6.1 0.0 11.9 9.9 7.9 9.6 14.5 39.4 20.9 10.5 8.6 17.1 19.3 10.9 8.7 6.5 13.1 12.0 17.0 9.5 13.1 12.0 10.9 9.4 14.7 9.0 1.7 5.3 12.1 3.8 4.4 2.7 3.3 2.7 4.0 4.0 4.1 4.3 3.2 5.7 4.3 4.9 3.1 4.2 2.9 28.0 32.4 46.6 41.2 26.1 22.4 19.9 21.8 19.4 15.8 20.8 20.5 4.7 8.4 12.8 14.0 14.6 0.0 2.7 15.9 8.7 19.6 5.9 6.6 7.3 49.1 9.8 9.2 0.0 11.2 4.3 9.3 7.6 15.1 4.2 8.1 17.5 16.7 7.4 12.4 137.7 11.5 8.2 15.1 6.4 5.3 7.4 8.1 5.8 9.2 10.3 15.1 6.5 9.5 39.0 8.3 13.8 5.4 7.5 5.6 8.3 PARP8 "FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846522 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "T-cells: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No Nucleoplasm "Midbody ring, Cytosol" "HPA049183: AB_2680667" "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favorable (1.12e-4)" 6.2 7.8 8.8 17.1 9.5 33.5 5.3 2.4 18.7 5.6 5.5 3.3 0.6 6.8 5.2 5.4 5.2 7.4 12.3 3.6 12.8 8.0 5.8 4.2 10.9 18.2 4.9 11.0 5.9 7.1 9.8 14.4 5.6 5.4 6.1 4.3 4.1 7.6 4.2 1.7 4.2 14.2 5.4 7.0 20.1 10.2 6.4 2.8 9.9 21.9 1.1 12.3 8.8 7.0 7.1 3.9 13.1 5.9 15.5 32.0 9.5 11.6 0.0 5.4 8.6 1.5 2.6 8.6 1.9 7.0 1.9 5.5 0.3 15.4 6.9 8.2 0.2 19.8 5.8 0.9 5.8 4.5 9.7 7.4 5.1 4.7 0.4 2.8 11.9 0.1 3.3 4.9 3.8 2.7 11.6 0.1 10.9 0.7 4.2 2.6 3.8 14.2 15.0 5.8 0.2 2.8 7.2 11.4 7.9 3.5 5.8 6.0 9.3 6.2 10.2 1.6 8.3 0.4 42.0 0.0 0.4 7.3 0.5 5.7 3.1 0.1 13.4 6.5 3.3 7.9 10.3 5.9 13.1 20.6 1.6 32.0 6.0 16.1 23.0 3.9 7.1 10.0 16.7 12.3 15.5 1.1 1.8 9.5 9.5 8.8 9.5 2.4 18.7 12.8 8.0 4.9 11.0 5.4 2.8 29.8 22.6 12.3 4.8 7.1 13.4 4.5 12.7 21.4 21.6 21.0 0.0 17.5 6.6 11.2 19.7 4.5 6.9 0.0 8.8 5.9 9.1 8.6 13.9 3.6 12.9 6.4 14.5 8.6 28.5 11.4 1.1 17.1 8.5 13.6 3.6 0.5 14.3 7.6 2.8 3.7 2.1 6.5 6.9 5.1 5.5 3.4 20.7 90.6 6.5 13.5 PARP9 "BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 35.1;BJ hTERT+ SV40 Large T+ RasG12V: 41.9;SK-MEL-30: 32.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Cytosol" Mitochondria "HPA066708: AB_2685707" "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 27.1 20.2 8.7 17.2 12.4 9.1 13.8 2.9 13.9 13.1 13.1 9.9 7.4 10.4 23.3 10.1 15.6 12.3 14.9 8.5 7.4 6.0 17.8 38.6 18.9 17.5 8.5 6.0 12.1 14.4 16.0 20.3 11.9 10.3 15.1 10.1 11.5 19.1 6.6 8.6 5.7 21.2 14.8 16.3 27.3 11.1 5.4 10.3 21.8 17.5 9.0 19.1 13.7 9.8 7.3 11.9 38.2 18.0 13.0 10.6 9.1 8.0 2.7 1.0 0.7 6.3 13.0 0.9 2.7 14.7 35.1 41.9 4.2 8.9 1.8 6.0 5.4 22.1 8.9 2.3 4.8 7.3 14.0 1.6 8.7 2.8 2.2 6.7 2.8 5.8 10.6 4.7 5.0 1.2 7.0 7.5 5.6 0.8 7.5 1.4 3.5 8.9 3.5 0.4 1.6 7.6 9.5 9.9 0.6 13.4 4.6 0.6 2.4 7.2 1.2 32.4 0.5 3.8 3.1 4.5 1.5 4.4 0.3 1.6 4.7 2.4 3.3 5.2 3.1 2.7 14.4 12.7 15.3 9.2 17.7 8.6 7.3 9.8 10.3 11.9 5.0 7.5 9.1 38.2 13.0 18.0 1.4 10.6 9.1 8.7 12.4 2.9 13.9 7.4 6.0 8.5 6.0 10.3 10.3 38.7 36.9 16.7 9.4 6.4 0.8 5.2 10.2 61.6 44.3 19.2 0.0 4.3 1.7 24.9 1.3 19.0 15.3 0.0 34.9 16.2 11.4 10.4 9.3 43.1 36.1 0.0 10.3 21.5 31.3 2.6 17.0 29.4 6.8 32.5 9.7 14.7 28.4 7.2 22.6 18.9 0.8 19.4 9.6 1.0 0.9 5.8 1.4 12.7 6.6 15.5 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Cell type enhanced" "Detected in many" 6 "Ito cells: 27.0;Peritubular cells: 23.0;Rod photoreceptor cells: 17.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol NA NA Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 5.0 6.8 9.2 11.6 0.8 1.4 12.3 4.8 1.5 4.5 6.3 5.5 5.1 2.6 1.0 1.1 10.0 12.6 10.4 4.2 3.3 10.6 9.9 7.2 12.6 9.7 0.5 9.8 11.3 0.7 3.3 4.6 1.3 1.9 3.2 11.2 9.3 3.6 3.1 5.7 11.6 10.3 10.2 5.9 4.1 18.5 9.3 3.2 1.7 11.4 16.3 4.9 2.9 5.6 2.1 5.1 4.7 7.1 4.2 6.1 5.6 7.8 6.4 4.8 4.9 12.4 3.8 7.4 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 3.0 9.3 10.6 1.0 2.4 2.3 2.8 2.5 6.7 1.2 3.5 3.9 0.8 0.0 1.2 7.7 2.4 1.8 0.0 1.8 1.5 0.9 2.5 3.5 1.0 1.6 1.6 0.0 27.0 5.3 2.2 5.5 1.9 11.8 1.0 2.9 1.6 0.6 0.0 23.0 1.0 17.7 0.0 0.3 14.7 12.7 1.3 0.2 13.1 2.7 0.7 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809620-27838095 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 19.4;testis: 67.9" "Group enriched" "Detected in many" 4 "Early spermatids: 218.2;Spermatocytes: 187.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 1.6" "Group enriched" "Detected in many" 10 "NK-cells: 2.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "A-431: 61.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 0.6 0.8 0.2 7.7 0.3 3.3 1.3 0.3 0.4 1.1 3.8 0.3 0.2 3.7 0.4 0.6 6.2 0.3 0.8 3.3 0.3 0.2 0.7 0.9 1.2 5.4 0.3 0.2 0.4 0.4 0.0 0.2 2.2 0.3 0.4 4.6 0.2 1.1 0.2 0.4 1.9 3.6 0.9 0.6 1.7 1.7 67.9 0.2 19.4 0.3 4.7 5.3 0.7 1.9 0.1 0.0 0.0 0.0 2.1 1.6 0.5 61.3 20.0 19.7 12.5 1.9 3.5 8.3 28.2 13.4 29.0 24.5 6.9 11.4 32.7 10.0 10.8 32.3 16.3 18.9 9.5 31.9 8.0 10.2 7.8 14.2 10.1 0.1 5.1 11.7 0.9 7.8 13.4 7.2 5.2 14.6 16.2 11.5 22.0 34.2 6.9 19.3 6.0 3.5 16.6 17.4 12.1 27.4 8.8 10.9 9.5 7.8 12.2 10.5 12.4 15.8 5.7 13.0 7.8 8.5 19.1 46.0 24.2 29.9 3.1 8.7 15.1 11.6 9.0 41.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 1.6 0.5 0.2 0.3 0.3 0.4 0.3 0.2 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.9 7.9 0.0 0.3 5.1 0.0 2.3 0.0 0.0 3.1 0.0 0.5 218.2 0.0 1.3 46.7 0.0 40.6 2.9 0.7 0.0 1.0 4.2 0.0 0.0 7.4 1.9 37.5 7.8 0.6 0.0 0.0 4.3 0.0 0.2 0.0 2.8 0.0 0.0 6.5 0.5 187.0 31.0 2.0 5.6 0.0 5.3 0.7 PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749443-149811420 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 9 "Early spermatids: 968.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol No No 8200000 Cytosol "HPA003239: AB_1079580" "prognostic unfavorable (4.02e-7)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.88e-4)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavorable (6.38e-4)" 19.1 18.4 35.7 13.0 43.0 28.5 19.3 33.5 58.3 20.2 16.9 19.2 12.4 14.7 16.0 22.2 17.9 15.8 11.0 43.9 35.0 38.8 21.3 29.5 15.1 14.6 35.1 46.0 16.2 14.6 16.4 15.5 17.2 57.4 22.1 18.1 11.6 17.2 21.4 69.5 14.7 13.6 19.6 28.6 12.0 12.7 29.1 19.2 18.1 19.3 15.9 17.9 14.4 13.7 31.6 53.0 51.2 58.0 30.0 37.4 51.6 21.8 17.3 17.7 22.1 38.1 31.5 19.7 35.9 20.5 28.5 36.1 50.2 16.7 27.6 30.5 30.3 33.9 27.2 30.4 35.8 41.2 19.2 44.0 42.2 32.5 49.0 25.5 50.2 51.9 15.7 26.5 32.5 35.2 20.6 26.9 23.4 60.3 27.1 34.0 65.0 24.3 38.3 14.4 21.5 19.4 20.2 23.0 19.9 27.7 16.1 33.8 13.0 27.2 43.5 23.3 22.7 26.3 35.8 20.0 16.8 21.4 31.9 38.9 17.1 26.6 28.2 26.5 33.6 33.4 40.0 58.0 51.2 30.2 53.6 30.1 31.6 30.6 32.7 53.0 24.2 28.5 32.5 30.8 30.0 52.2 23.9 37.4 51.6 35.7 43.0 33.5 58.3 35.0 38.8 35.1 46.0 57.4 19.2 50.6 33.8 61.0 64.4 155.6 73.9 150.1 58.6 62.9 33.0 75.0 35.3 145.0 66.3 107.5 968.1 68.2 50.9 46.7 96.6 180.3 97.5 60.4 104.1 112.2 107.3 62.0 53.0 50.3 78.3 318.9 66.4 94.5 131.6 139.7 62.0 111.0 87.2 56.9 69.3 69.4 50.7 109.9 107.2 205.7 85.4 137.8 124.0 71.9 52.4 51.7 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 73.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 24.8 22.2 15.3 19.9 18.7 25.8 18.0 14.2 17.8 13.6 25.3 23.0 21.1 41.1 18.2 18.7 25.2 15.0 19.8 36.0 14.8 13.8 20.2 17.8 18.7 15.6 16.6 14.1 15.6 13.9 16.0 12.1 14.2 20.5 13.3 16.5 14.4 17.1 19.2 45.8 32.8 37.2 19.5 18.3 23.4 18.1 19.4 18.6 13.2 14.8 28.0 19.0 17.6 16.7 7.8 8.7 20.5 9.8 7.9 13.5 4.6 28.7 11.6 8.1 11.9 16.7 18.6 12.3 22.0 15.7 18.9 16.7 28.3 10.5 7.4 73.8 25.2 19.9 22.5 12.9 16.9 16.2 13.4 9.0 21.2 12.2 12.0 15.0 10.2 18.2 15.7 13.0 18.3 13.1 12.2 20.2 6.9 11.8 16.5 18.8 24.3 6.4 5.4 7.0 18.1 17.3 10.6 10.4 11.9 11.6 16.2 8.0 5.9 14.9 25.7 14.3 11.8 37.7 12.8 30.2 15.1 8.4 20.5 29.7 15.3 29.1 13.6 23.1 14.3 18.9 7.5 8.7 9.2 9.6 9.2 8.0 7.8 7.2 10.2 8.7 5.7 4.6 6.8 20.5 7.9 9.8 5.6 13.5 4.6 15.3 18.7 14.2 17.8 14.8 13.8 16.6 14.1 20.5 18.6 14.9 18.8 17.9 8.2 12.9 14.3 58.5 17.8 33.5 15.9 14.0 23.6 10.4 11.6 21.4 63.4 19.5 43.0 0.0 19.9 14.2 13.7 9.7 19.7 31.7 32.6 7.9 21.2 25.2 28.9 52.1 18.4 30.0 18.6 33.3 20.4 11.8 20.8 14.8 26.5 19.4 12.4 25.8 13.7 30.0 10.6 18.7 15.6 22.7 20.5 11.0 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 15.6" "Group enriched" "Detected in some" 6 "Early spermatids: 21.7;Late spermatids: 58.8;Muller glia cells: 30.2" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 2.7;neutrophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "AF22: 8.3;CACO-2: 17.8;HEL: 21.9;Hep G2: 9.1;NTERA-2: 9.4;SCLC-21H: 6.5;SuSa: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain NA NA "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.8 1.1 12.0 1.1 11.4 2.0 1.0 3.1 23.9 1.6 1.1 13.7 2.3 1.3 3.2 1.7 2.8 5.7 1.7 4.2 10.0 6.0 1.0 0.6 2.1 0.6 7.8 10.5 4.0 3.1 0.7 1.4 3.6 10.7 2.3 1.3 2.1 1.0 6.4 0.7 0.7 1.1 6.1 10.3 1.0 0.9 15.6 8.7 0.0 0.6 0.0 0.7 0.9 0.4 0.4 0.5 2.7 0.5 0.6 0.2 1.4 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 17.8 0.0 0.0 4.7 0.0 0.0 0.9 3.9 0.0 0.0 0.0 0.1 21.9 0.0 9.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.2 0.5 9.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 6.5 5.2 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.3 0.6 0.2 2.7 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.2 0.2 2.2 0.6 0.5 0.5 0.2 1.4 12.0 11.4 3.1 11.3 10.0 6.0 7.8 10.5 10.7 8.7 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 6.7 1.2 0.0 0.0 0.1 0.0 0.7 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.0 1.7 0.0 0.0 58.8 0.3 0.0 0.0 0.0 0.0 30.2 0.3 0.0 2.5 0.0 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.0 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900965-81911464 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 70.8" "Group enriched" "Detected in many" 11 "Early spermatids: 615.4;Late spermatids: 2143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Approved Nucleoplasm,Cytosol NA NA 7000 Cytosol Nucleoplasm "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 13.6 5.5 13.3 5.7 12.7 5.3 10.4 12.2 17.0 6.5 16.2 13.4 6.4 30.7 5.8 8.6 7.6 12.2 8.0 17.7 14.0 11.8 21.7 46.5 7.2 6.3 13.4 16.0 7.8 11.5 8.2 4.6 6.0 15.9 10.1 8.5 5.8 10.8 6.6 13.5 4.5 26.5 5.0 14.3 4.1 11.5 70.8 11.0 5.6 6.7 6.8 5.8 7.5 4.4 7.3 6.6 2.1 3.5 4.7 8.4 4.0 11.8 6.8 5.5 15.5 27.6 14.5 8.1 8.5 18.4 12.0 14.3 26.7 12.4 4.1 4.7 8.9 22.3 9.8 8.3 15.9 7.0 1.2 6.8 9.0 9.4 61.2 29.5 9.0 7.6 11.9 9.2 10.8 8.4 4.3 11.1 12.7 16.7 8.6 8.9 10.0 10.7 11.1 4.4 41.7 7.3 7.1 5.9 14.7 14.4 22.5 7.0 6.4 6.4 35.5 8.3 11.3 9.8 21.4 7.4 8.9 5.8 6.6 7.0 5.6 2.3 4.0 9.2 12.1 8.7 2.1 3.5 1.2 7.1 3.4 4.6 6.0 8.4 7.2 6.6 7.3 7.0 7.2 1.0 4.7 3.0 6.5 5.0 4.0 13.3 12.7 12.2 17.0 14.0 11.8 13.4 16.0 15.9 11.0 0.0 15.9 13.0 6.8 4.7 11.8 14.9 56.0 10.7 4.5 24.4 0.0 67.4 101.2 15.9 615.4 7.1 65.6 23.3 16.0 30.7 6.8 9.0 9.2 125.6 20.2 15.9 13.4 20.3 10.0 2143.8 25.6 9.3 32.1 21.6 22.6 19.8 17.5 17.3 24.4 119.0 7.1 25.8 11.4 131.3 17.2 5.0 42.4 12.5 30.7 4.5 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69328621-69330595 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Cell type enhanced" "Detected in single" 21 "Alveolar cells type 1: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No Mitochondria Nucleoplasm "HPA063409: AB_2685007" "unprognostic (4.28e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favorable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 6.6 7.9 4.8 7.8 4.5 5.3 4.8 3.1 6.9 3.6 7.6 3.8 3.3 7.1 5.3 5.6 8.4 4.4 6.5 3.8 4.6 3.3 14.9 30.2 3.7 7.0 3.0 5.2 5.0 14.2 8.2 3.9 4.9 4.4 5.3 4.1 4.3 12.8 4.6 10.4 6.0 5.2 3.4 2.3 5.0 8.3 3.7 2.0 10.2 7.3 9.2 6.2 3.7 4.0 10.3 3.2 2.5 2.8 1.7 6.9 1.5 9.0 6.1 1.2 2.9 1.8 1.4 10.7 7.6 2.0 5.4 4.7 15.0 6.4 16.7 10.1 2.6 2.5 13.0 3.7 4.0 2.2 4.0 31.0 8.5 5.8 21.4 3.7 11.8 6.8 2.8 7.1 4.8 2.3 0.9 3.1 8.6 20.3 1.9 2.9 11.6 9.2 12.4 7.8 3.3 11.2 21.7 1.9 15.5 4.3 5.7 10.4 8.3 13.1 2.3 6.4 0.5 12.9 3.8 4.7 4.7 8.8 5.4 8.7 15.8 10.5 19.7 3.1 8.8 6.0 0.0 2.8 2.5 1.2 1.6 3.1 4.3 3.9 3.9 3.0 10.3 6.9 2.5 0.0 1.7 1.5 3.2 3.0 1.5 4.8 4.5 3.1 6.9 4.6 3.3 3.0 5.2 4.4 2.0 3.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283152-287215 "Enzymes, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "pancreas: 286.5" "Cell type enriched" "Detected in some" 6 "Exocrine glandular cells: 253.2" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Region enhanced" "Detected in many" "cerebellum: 15.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.2;HEK 293: 11.6;Hep G2: 8.6;Karpas-707: 4.0;MCF7: 6.1;SH-SY5Y: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" NA NA "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" 0.3 0.3 2.1 0.2 1.5 0.3 0.2 15.3 3.0 0.2 0.7 4.3 0.2 2.9 0.2 0.3 0.2 0.2 0.8 0.4 2.8 3.0 0.2 0.2 0.2 0.2 4.0 0.5 0.4 286.5 0.2 0.2 0.5 2.2 0.2 0.2 0.2 0.3 0.2 0.2 0.2 1.0 0.2 5.4 0.2 10.2 0.3 2.8 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.1 0.1 0.1 5.2 0.2 0.7 0.1 11.6 0.0 0.3 8.6 1.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.2 0.0 0.4 4.0 0.2 6.1 0.2 0.6 0.4 2.1 0.0 0.1 0.0 1.1 0.0 0.0 2.2 5.0 0.0 0.1 0.0 0.7 1.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.5 15.3 3.0 2.8 3.0 4.0 0.5 2.2 2.8 0.0 0.3 0.0 0.0 0.5 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 253.2 0.6 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.0 0.2 39.2 0.3 0.4 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.9 0.0 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746392-43773279 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Syncytiotrophoblasts: 877.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 390000000 "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 16.9 21.2 10.0 20.5 13.5 20.8 31.1 12.7 9.2 24.7 19.4 12.3 33.9 22.2 19.7 42.4 21.7 18.4 25.1 20.6 10.2 12.7 27.3 112.5 20.0 34.6 12.4 10.3 22.4 46.8 21.1 21.7 44.0 13.3 24.6 21.2 13.7 43.4 36.9 8.7 17.9 28.8 15.8 11.4 25.2 20.5 17.1 14.3 15.6 74.0 16.4 19.8 14.7 28.3 7.7 18.3 13.5 10.8 11.7 14.1 14.5 12.3 4.6 9.8 21.9 19.9 21.4 30.1 24.7 24.5 18.4 22.9 12.9 12.7 14.1 16.1 28.2 12.3 19.7 12.4 24.0 16.1 10.2 18.4 19.1 7.4 11.9 32.8 10.7 13.9 13.7 19.9 13.9 23.5 21.7 32.0 4.5 11.0 6.9 17.9 4.2 3.6 12.2 9.9 19.0 18.7 7.1 15.4 10.6 15.7 10.1 9.9 11.0 20.6 19.8 7.8 10.4 13.8 11.0 21.6 15.3 8.1 12.3 12.0 3.2 3.6 14.8 19.6 17.0 11.5 10.0 10.3 13.5 13.4 10.5 14.1 6.5 8.5 10.8 9.6 7.7 7.2 8.4 2.9 11.7 10.8 18.3 6.7 14.5 10.0 13.5 12.7 9.2 10.2 12.7 12.4 10.3 13.3 14.3 178.6 134.5 154.1 249.6 170.7 50.3 49.5 142.7 231.6 287.8 158.7 39.3 559.5 59.7 337.0 18.9 151.7 227.1 23.3 345.2 636.6 296.9 292.3 254.2 280.2 396.2 66.7 178.5 269.5 152.1 20.5 234.7 267.6 231.2 285.9 259.4 139.7 260.6 167.0 260.3 106.7 46.2 122.9 160.2 185.1 135.1 129.7 877.1 174.3 233.4 256.5 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028641 "Enzymes, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 164.3" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 542.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 12000000 "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavorable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 17.6 13.0 7.7 25.6 11.9 7.4 27.4 5.1 7.9 25.5 20.9 12.1 28.8 18.2 19.4 46.3 15.2 20.8 28.1 16.9 7.3 8.0 27.7 164.3 19.1 29.1 11.6 6.2 19.4 76.3 7.0 19.1 24.7 12.0 18.0 21.9 7.8 36.4 26.5 5.8 10.1 21.3 17.8 13.9 27.9 23.7 11.5 11.3 19.2 89.8 11.9 24.3 17.4 22.6 26.6 63.3 16.2 21.2 21.5 35.9 34.5 32.4 30.9 33.6 93.9 30.7 21.9 48.7 45.7 30.6 26.2 42.8 25.6 87.8 23.4 102.6 37.5 72.2 21.3 22.6 43.3 23.1 16.6 13.3 11.2 8.9 56.1 41.2 25.5 31.7 21.5 19.4 28.7 23.1 34.2 53.2 12.0 18.3 63.8 23.0 35.5 24.3 29.1 50.1 66.4 18.0 16.0 26.1 56.6 30.6 25.5 10.7 28.2 41.5 29.9 15.9 41.9 17.0 19.7 29.0 20.7 11.7 50.1 32.1 48.6 21.8 16.4 48.3 30.2 70.3 16.2 20.1 12.1 34.3 21.2 35.9 26.6 22.6 26.7 19.4 15.1 21.5 22.7 2.7 21.5 21.0 63.3 16.6 34.5 7.7 11.9 5.1 7.9 7.3 8.0 11.6 6.2 12.0 11.3 26.8 33.4 29.0 71.4 30.8 3.3 20.4 96.8 65.6 44.3 40.1 3.9 152.3 13.3 102.2 2.7 35.1 89.5 46.7 79.9 277.0 90.5 103.6 57.6 542.5 131.4 0.0 59.1 95.8 80.7 3.2 54.7 53.4 82.7 48.7 104.5 19.3 96.2 87.1 40.3 54.4 6.1 32.3 34.2 53.4 71.9 25.0 192.7 54.6 97.0 59.2 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067062-123225227 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 66.0" "Cell type enhanced" "Detected in many" 8 "Extravillous trophoblasts: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 2900000 "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 11.6 17.1 2.6 11.2 3.1 6.3 9.3 1.0 4.0 10.0 11.0 2.4 10.9 5.6 12.2 17.1 6.7 9.1 22.2 7.2 2.5 1.2 11.0 66.0 14.4 7.1 2.2 1.8 11.4 18.3 5.2 12.1 29.1 1.9 14.3 10.8 12.7 10.8 7.6 8.1 6.1 8.2 9.5 2.3 8.6 17.6 18.0 2.5 3.2 18.2 5.5 7.9 7.8 6.9 3.2 12.8 0.3 9.0 0.5 2.4 2.3 8.2 5.1 6.4 7.7 29.4 26.7 34.1 15.8 26.5 8.8 24.4 16.3 7.6 0.0 20.6 24.4 5.7 4.4 2.8 9.6 9.4 0.2 3.1 3.6 1.5 19.4 12.2 9.1 0.6 22.8 14.5 6.0 12.6 9.5 29.8 3.5 4.6 21.6 6.0 10.1 2.4 10.6 4.7 18.9 5.3 2.3 4.6 22.8 7.4 4.8 6.9 4.2 7.7 8.6 13.5 10.9 7.5 11.1 16.6 2.3 7.3 10.6 4.2 6.4 1.7 3.7 7.3 7.2 7.7 0.0 9.0 0.3 1.4 2.2 2.4 3.2 1.0 0.9 5.4 0.8 0.6 0.6 0.2 0.5 0.4 12.8 0.0 2.3 2.6 3.1 1.0 4.0 2.5 1.2 2.2 1.8 1.9 2.5 17.9 27.8 1.5 3.6 4.4 9.3 2.0 25.5 8.1 13.6 5.2 37.3 39.8 0.0 28.0 1.1 21.8 3.3 0.0 25.3 119.9 23.6 13.9 3.5 42.3 10.8 0.0 8.1 37.4 8.4 1.5 22.5 4.5 8.5 1.8 26.1 2.0 13.8 3.5 20.8 4.9 29.6 12.9 7.3 1.2 1.5 3.6 42.0 2.2 16.3 4.3 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Extravillous trophoblasts: 955.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 53000000 "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 26.9 32.7 16.7 25.0 29.9 19.9 28.7 11.3 16.8 33.4 26.1 13.9 53.7 20.4 30.4 76.1 27.1 25.5 22.4 32.7 14.2 13.9 42.1 118.4 30.4 36.3 17.8 12.7 26.5 141.6 24.9 23.3 39.5 19.0 22.6 30.1 14.6 53.4 45.0 15.7 16.1 28.4 26.5 14.3 35.1 30.9 12.4 19.5 18.1 97.9 20.1 29.7 21.9 30.6 45.2 61.0 52.0 46.2 51.5 52.2 59.7 33.2 36.1 51.7 81.1 66.6 57.6 92.0 80.9 75.1 42.5 57.3 51.2 65.7 54.0 57.0 79.1 82.6 27.3 38.8 67.7 45.7 42.3 30.6 43.8 28.3 83.1 72.1 44.8 32.9 41.5 52.1 41.1 74.2 78.8 95.7 20.5 37.6 116.5 41.9 39.4 17.2 46.5 43.2 108.3 28.6 41.4 52.7 97.8 60.5 40.2 33.2 66.5 31.9 46.8 45.4 70.0 16.5 76.1 47.0 39.9 51.0 35.9 46.7 110.0 67.8 35.0 53.9 56.4 55.8 52.0 44.4 20.5 47.5 46.2 52.2 45.2 37.7 44.7 48.6 33.1 18.4 31.0 8.1 51.5 33.9 61.0 37.7 59.7 16.7 29.9 11.3 16.8 14.2 13.9 17.8 12.7 19.0 19.5 53.6 94.6 111.7 205.7 91.5 66.3 27.4 152.8 108.4 161.5 186.7 27.5 420.2 36.5 263.9 6.1 114.4 100.2 23.3 210.7 955.4 173.7 256.1 129.2 285.4 369.6 39.7 151.3 244.9 137.9 12.1 112.2 137.1 189.0 126.2 149.4 95.2 191.3 100.8 126.9 98.3 45.7 84.1 115.4 95.8 139.7 89.6 463.4 112.4 196.3 240.5 PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 96.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 5.9;granulocytes: 16.0;T-cells: 15.8" "Cell line enhanced" "Detected in many" "U-266/70: 32.0;U-87 MG: 32.7" "Low region specificity" "Detected in all" "CAB017554, HPA027376" Approved NA NA 22000 "CAB017554: AB_2161138, HPA027376: AB_1855139" "unprognostic (2.14e-1)" "prognostic unfavorable (7.30e-5)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (6.47e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-3)" "unprognostic (6.44e-2)" "unprognostic (5.44e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.10e-8)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (5.34e-2)" 9.9 16.2 6.8 11.0 10.5 13.4 16.7 7.1 15.6 7.3 15.3 3.3 2.9 15.5 5.4 8.0 11.2 4.4 5.8 27.6 6.9 5.2 6.8 14.2 6.1 21.4 7.2 5.2 19.5 7.2 3.4 7.5 7.9 7.2 6.5 13.1 7.6 14.1 7.6 9.6 24.7 8.4 5.2 10.7 14.2 12.5 11.0 6.7 10.3 5.1 5.0 20.8 18.0 9.8 5.9 2.3 16.0 2.2 1.4 15.8 6.2 14.4 0.6 3.7 9.3 1.5 2.3 5.3 12.7 10.3 6.4 13.7 3.7 3.1 13.7 7.0 3.9 5.3 6.3 2.5 7.9 20.5 2.7 5.1 16.7 3.4 4.3 2.7 8.3 6.2 3.0 2.9 4.4 7.5 8.9 3.4 7.3 3.5 9.5 8.4 1.5 5.2 10.4 9.1 2.9 4.0 5.5 6.1 22.1 3.3 4.6 7.0 8.0 3.3 3.9 4.8 3.3 2.5 3.4 3.9 10.2 3.3 5.3 3.4 32.0 18.5 11.3 32.7 6.0 2.0 12.2 2.2 16.0 2.5 1.5 3.0 4.7 4.2 2.8 2.3 5.9 15.8 9.6 8.5 1.4 1.9 0.4 8.0 6.2 6.8 10.5 7.1 15.6 6.9 5.2 7.2 5.2 7.2 6.7 3.0 5.3 32.2 5.4 44.5 26.8 32.3 5.1 1.4 2.3 3.5 45.2 9.1 5.0 7.7 96.0 8.9 6.0 0.0 3.3 9.6 8.4 5.5 5.7 11.9 8.7 52.4 7.5 23.9 12.9 34.3 3.1 8.8 28.7 5.4 5.2 7.6 9.0 14.0 3.5 1.5 18.9 6.5 12.3 6.3 7.7 37.9 3.4 12.5 6.0 2.1 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.0" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favorable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 20.6 26.1 17.2 5.2 27.5 3.2 10.8 53.7 34.4 10.1 16.1 16.1 10.1 15.5 13.1 69.8 12.5 14.4 11.5 51.7 18.2 13.0 33.7 27.8 9.0 5.7 14.6 20.9 27.7 24.1 16.9 7.5 8.6 14.2 12.7 12.4 19.5 14.0 16.5 101.0 10.6 16.5 15.1 9.9 7.8 13.6 7.2 11.4 6.2 15.6 31.4 7.4 13.8 9.4 11.3 20.1 8.9 12.9 16.5 17.4 12.2 6.4 9.2 11.1 10.0 11.8 8.9 1.2 7.0 10.4 10.5 10.2 0.8 7.0 8.1 11.7 19.5 7.1 3.1 7.4 2.8 10.3 16.3 10.3 7.2 9.1 6.8 6.3 0.0 7.8 18.7 10.8 6.8 0.5 18.5 9.1 10.4 2.9 8.1 5.9 8.2 6.0 0.0 2.4 19.5 9.0 9.1 24.9 10.9 5.7 5.5 7.4 11.2 9.9 3.1 4.7 14.2 18.3 7.2 4.7 12.3 10.1 8.4 5.1 16.0 15.1 4.4 18.0 2.6 7.9 8.9 12.9 6.8 14.0 9.8 11.1 11.1 12.5 14.8 14.2 11.3 14.6 15.0 2.2 16.5 10.5 20.1 17.4 12.2 17.2 27.5 53.7 34.4 18.2 13.0 14.6 20.9 14.2 11.4 8.9 9.3 13.6 13.9 13.5 20.8 5.0 10.2 1.4 11.4 19.2 5.9 15.1 49.7 8.0 7.3 8.3 46.6 0.0 7.9 3.4 19.5 7.6 1.1 39.8 16.7 41.3 13.3 13.5 13.7 15.0 22.5 7.9 23.6 15.4 45.3 33.6 7.9 43.6 49.5 118.5 9.2 19.4 12.1 3.3 4.4 16.4 6.6 15.8 37.1 8.4 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465221-24539837 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria NA NA Mitochondria Nucleoli "HPA046583: AB_2679707, HPA072492: AB_2686526" "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 9.6 5.6 5.7 9.8 17.3 16.3 12.8 3.3 23.6 8.0 14.7 5.5 5.6 13.6 7.3 15.7 9.5 13.2 7.0 16.9 12.5 6.8 13.7 11.1 11.2 13.4 6.2 13.7 11.0 7.3 12.8 14.1 7.7 14.9 8.3 10.1 9.9 19.3 5.2 3.9 14.2 15.6 8.6 6.1 17.9 12.7 23.1 4.8 12.5 6.2 4.1 14.9 10.3 9.2 4.5 7.2 36.4 10.9 7.1 11.0 6.7 9.0 4.6 3.9 6.6 0.1 0.0 4.1 2.7 2.4 3.7 6.5 0.4 11.1 9.2 1.9 0.7 10.5 2.1 11.3 6.9 10.0 7.8 5.4 4.9 5.3 2.6 1.3 4.2 4.8 0.7 3.1 0.9 0.9 0.4 5.5 9.6 0.9 14.0 0.5 17.0 7.8 5.4 7.0 9.7 5.4 4.0 7.0 13.5 3.2 17.7 2.5 3.2 14.7 6.0 4.6 6.2 8.3 1.6 0.2 2.6 3.8 4.8 3.2 9.0 6.9 11.0 7.1 6.4 5.4 9.4 8.9 21.3 7.6 10.9 11.0 4.5 6.2 6.2 7.2 4.1 4.9 5.7 36.4 7.1 10.4 2.3 5.1 6.7 5.7 17.3 3.3 23.6 12.5 6.8 6.2 13.7 14.9 4.8 3.0 1.3 2.9 8.6 4.0 3.4 6.3 0.0 1.4 2.3 1.8 0.0 4.0 3.3 3.6 53.4 2.8 4.5 0.0 4.5 26.4 3.2 5.2 5.7 4.2 13.2 7.9 4.1 4.3 18.9 22.4 3.4 9.6 15.1 8.2 2.4 3.2 2.8 0.0 5.3 11.3 3.9 0.0 9.2 6.4 6.3 3.9 14.9 14.9 3.3 7.1 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596491 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 351.0;skeletal muscle: 497.0" "Cell type enhanced" "Detected in many" 11 "Cardiomyocytes: 766.1;Collecting duct cells: 359.4;Kupffer cells: 351.0" "Cancer enhanced" "Detected in all" "renal cancer: 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 14.2;eosinophil: 15.6;intermediate monocyte: 26.1;myeloid DC: 7.1;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 11 "dendritic cells: 7.1;granulocytes: 15.6;monocytes: 26.1" "Cell line enriched" "Detected in some" 7 "ASC diff: 107.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056731 Approved NA NA "HPA056731: AB_2683218" "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 90.7 41.9 6.9 5.9 14.6 0.4 49.1 2.5 9.1 12.3 30.9 9.0 150.6 13.6 10.7 13.7 29.0 14.7 15.6 351.0 9.2 3.7 27.7 39.5 14.1 6.1 18.2 2.4 46.6 102.9 0.8 8.1 19.4 26.1 29.3 8.4 4.4 8.4 150.6 497.0 10.2 46.2 20.7 13.9 19.0 21.2 10.8 17.4 1.0 13.4 12.3 2.5 23.8 46.4 0.7 7.1 15.6 26.1 1.4 0.0 4.7 0.0 8.0 0.3 2.0 107.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 1.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.7 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.1 0.5 0.1 0.6 0.0 0.6 1.6 0.5 0.2 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 14.2 15.6 0.0 26.1 0.0 0.1 0.0 0.0 7.1 0.7 0.0 0.0 1.0 1.4 15.6 0.2 0.0 4.7 6.9 14.6 2.5 9.1 9.2 3.7 18.2 2.4 26.1 17.4 29.8 13.6 12.6 245.0 9.3 0.0 766.1 28.1 96.4 52.4 359.4 0.0 2.7 11.6 4.3 10.2 89.9 112.9 0.0 4.7 0.7 44.7 113.9 4.7 93.7 42.3 0.0 53.1 160.8 351.0 2.5 124.3 29.1 86.0 1.8 47.0 11.6 8.2 42.1 42.1 35.5 0.3 161.7 181.3 0.2 0.5 8.2 9.2 5.7 27.3 131.1 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926066 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.2" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 71.4;Early spermatids: 99.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 38.9;cerebral cortex: 62.2;olfactory region: 32.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 39.5;hTERT-RPE1: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 5.1 32.3 11.0 4.6 38.9 5.9 7.9 7.5 62.2 7.5 4.3 4.7 1.6 3.3 7.7 8.6 8.0 6.1 9.6 22.9 10.1 8.0 6.3 2.2 6.0 5.6 5.1 32.5 9.7 9.3 20.6 4.2 6.6 4.4 5.2 6.2 4.4 6.6 4.7 31.8 3.2 5.5 5.5 3.4 5.8 5.5 12.9 4.8 4.1 9.3 7.0 5.8 7.7 5.1 11.0 12.7 7.8 21.5 2.8 19.5 8.8 7.9 3.9 8.6 3.6 7.1 13.1 2.8 6.3 7.0 7.4 8.7 4.1 29.6 4.4 21.2 10.0 39.5 17.7 3.6 5.3 11.0 0.4 1.8 2.1 4.9 1.4 8.2 1.0 3.0 8.4 10.5 12.6 20.2 39.3 16.7 4.0 0.7 7.3 9.0 1.9 6.2 3.2 3.9 8.6 5.1 1.5 5.1 0.8 5.1 5.5 0.8 3.7 4.1 0.4 19.3 7.3 1.3 1.2 29.6 9.0 5.8 21.0 7.4 4.1 1.7 3.7 11.5 3.7 7.9 3.1 15.4 7.8 5.6 14.3 5.3 9.3 9.1 7.2 12.7 11.0 5.5 4.8 1.8 2.8 21.5 2.1 19.5 8.8 11.0 38.9 7.5 62.2 10.1 8.0 5.1 32.5 4.4 4.8 11.9 5.6 13.4 11.2 11.6 34.7 71.4 22.9 22.7 17.0 15.7 7.9 3.5 5.0 24.3 99.2 14.7 6.0 0.0 11.9 3.2 11.6 13.3 5.8 2.5 5.7 9.5 9.8 14.1 20.8 22.0 10.6 16.2 10.1 2.8 5.2 19.0 22.2 7.0 12.7 8.6 10.6 6.5 12.7 7.2 9.7 9.5 3.7 10.1 8.9 17.0 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA Mitochondria "HPA019950: AB_1855156, HPA062059: AB_2684671" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favorable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 10.7 7.2 7.4 3.7 10.5 3.2 8.7 11.5 16.5 4.9 7.5 10.1 5.7 10.4 7.9 7.2 8.9 7.2 6.0 4.8 7.4 7.1 18.1 16.5 8.6 5.0 9.0 9.4 14.9 13.8 12.0 7.0 7.7 16.0 7.8 8.4 8.5 7.1 6.9 6.3 4.7 6.2 4.6 6.3 4.0 6.7 8.6 8.9 4.6 18.0 4.0 5.9 6.3 5.5 3.3 1.3 1.8 0.4 6.1 6.3 2.0 7.2 8.9 5.5 10.8 14.9 7.7 6.9 3.8 14.8 8.9 13.4 18.1 5.2 10.2 5.5 5.3 8.5 9.3 16.0 8.6 8.6 2.4 8.1 5.1 4.5 11.8 8.1 6.5 9.0 5.8 6.5 12.6 13.1 9.7 3.8 11.5 9.8 7.3 7.9 4.8 12.6 4.7 6.5 4.9 11.3 12.5 7.7 16.0 4.7 7.8 11.1 6.3 12.3 5.0 4.6 4.5 6.7 3.2 3.5 5.4 7.4 3.3 5.6 13.0 12.0 10.1 7.5 5.2 5.4 1.3 0.4 1.8 6.3 0.3 5.2 1.8 3.1 5.1 1.3 3.3 4.5 5.0 1.3 6.1 0.2 0.8 0.9 2.0 7.4 10.5 11.5 16.5 7.4 7.1 9.0 9.4 16.0 8.9 8.9 18.5 5.9 4.3 4.6 7.9 4.5 7.6 1.4 4.5 8.7 13.7 9.1 6.6 2.7 0.1 1.8 5.1 0.0 2.5 1.6 4.2 6.7 5.8 11.5 2.1 4.8 3.5 6.7 0.6 1.9 2.8 0.8 3.3 0.0 4.0 8.4 2.8 5.8 4.2 8.1 6.3 0.0 3.1 4.4 1.3 2.0 3.0 1.9 5.8 7.0 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537964-2603188 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199" Supported Supported Cytosol NA NA Cytosol "CAB004272: AB_626657, HPA035199: AB_2674514" "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.1 14.9 21.0 11.6 31.9 14.2 14.2 29.6 26.4 10.5 15.6 14.5 10.4 17.2 13.0 14.0 13.8 15.3 10.8 14.8 17.2 13.5 17.6 12.6 13.4 13.5 11.3 20.6 14.8 28.2 34.5 13.9 17.1 16.7 13.6 15.3 12.8 16.5 13.2 18.2 14.1 19.1 12.9 10.9 13.7 13.4 14.2 10.1 14.1 16.1 10.6 13.9 12.3 13.3 5.1 9.1 14.7 9.4 5.4 6.0 4.5 8.5 11.0 13.8 9.1 14.2 11.9 14.6 14.3 9.2 12.8 10.8 11.0 10.3 14.1 9.8 13.8 10.9 13.6 16.4 10.3 12.2 25.1 11.1 7.5 14.5 18.2 12.4 12.3 19.7 10.8 19.0 13.8 9.2 12.4 11.7 12.9 13.9 11.5 15.0 18.1 12.4 8.7 8.7 16.0 9.8 25.4 13.7 12.8 12.4 7.7 21.7 11.2 18.5 21.3 7.7 9.2 19.7 15.5 14.3 14.0 13.9 13.6 12.3 15.3 14.6 22.1 6.7 8.6 12.1 3.9 7.9 9.0 5.1 9.3 4.8 5.1 4.7 6.0 6.7 4.5 5.3 4.9 14.7 5.4 9.4 9.1 2.3 4.5 21.0 31.9 29.6 26.4 17.2 13.5 11.3 20.6 16.7 10.1 14.9 18.4 17.1 18.3 23.7 56.0 28.1 43.3 21.4 14.8 10.4 51.1 38.1 11.6 20.5 12.0 15.5 32.9 0.0 20.5 24.1 22.4 24.3 7.0 38.5 22.9 69.9 20.7 23.9 46.7 21.8 29.4 21.5 20.3 30.7 31.7 39.4 25.3 17.5 41.8 34.2 41.5 45.3 18.6 36.7 40.5 29.7 87.5 17.5 27.9 19.6 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA Mitochondria "CAB068215: AB_2665674, HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 12.2 16.5 11.7 14.3 14.0 12.5 18.6 14.6 22.1 8.4 13.9 8.3 9.9 13.6 10.4 9.9 22.0 11.5 13.4 22.6 14.2 12.1 13.9 26.3 8.5 17.6 9.9 11.8 11.9 30.2 8.1 9.6 10.3 10.4 10.1 10.4 8.5 16.0 11.4 27.4 15.2 12.0 10.2 7.5 13.0 11.7 13.6 5.1 17.6 16.3 17.4 14.5 11.6 12.9 4.0 6.7 7.7 3.1 3.3 3.7 1.4 19.2 37.1 7.9 22.3 5.6 4.5 18.6 9.9 6.2 16.7 9.4 46.2 11.2 24.9 18.4 8.6 8.6 16.9 37.2 18.7 6.9 12.2 29.3 29.9 17.4 24.1 12.7 28.3 17.5 5.6 13.8 19.5 21.1 5.5 12.2 20.4 37.4 10.3 6.5 34.9 38.3 28.3 30.1 16.9 26.3 29.4 8.8 19.9 10.8 26.8 29.1 16.4 17.2 24.2 10.7 6.6 30.6 15.7 10.5 8.5 18.6 17.1 24.1 21.6 31.7 35.8 11.1 23.2 14.2 7.7 2.4 0.7 2.5 2.5 3.7 3.6 2.9 2.8 2.0 4.0 2.9 3.6 2.0 3.3 3.1 6.7 2.0 1.4 11.7 14.0 14.6 22.1 14.2 12.1 9.9 11.8 10.4 5.1 3.0 6.7 6.7 10.3 10.2 9.2 12.6 20.4 4.0 0.0 5.2 13.7 5.6 5.0 4.0 12.9 5.3 6.3 0.0 6.7 12.5 3.3 9.0 0.0 21.9 6.4 6.4 12.6 4.3 6.9 15.9 5.5 4.8 3.3 2.8 8.9 3.9 6.9 5.8 6.3 9.0 12.2 6.5 5.5 9.8 9.4 15.2 5.1 4.4 14.0 11.6 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023065 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 73.7;bone marrow: 130.1" "Cell type enhanced" "Detected in single" 35 "Alveolar cells type 2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 190 "eosinophil: 63.0;neutrophil: 73.7" "Lineage enriched" "Detected in single" 205 "granulocytes: 73.7" "Cell line enhanced" "Detected in some" "A549: 7.3;HEK 293: 4.1;HeLa: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 47000000 Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 0.7 0.1 0.2 0.5 0.4 130.1 0.2 0.4 0.2 0.1 0.3 0.3 0.0 0.2 0.1 0.1 0.2 0.4 0.1 10.9 0.2 0.2 0.2 1.5 10.9 1.0 0.2 0.0 0.7 0.2 0.1 1.4 4.1 0.1 0.1 0.1 0.5 0.7 0.1 1.3 0.3 0.2 0.1 0.1 26.9 0.2 0.9 0.0 7.5 1.3 0.0 0.5 0.1 5.5 0.0 0.0 73.7 0.3 0.0 0.0 0.4 0.6 7.3 1.2 0.8 0.0 0.0 2.0 0.6 0.0 0.0 0.0 1.2 0.6 2.0 0.2 0.0 0.6 2.7 0.0 0.0 0.0 1.9 4.1 0.8 3.5 0.3 0.0 0.4 2.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.7 0.6 0.0 0.5 0.4 2.2 0.4 0.0 2.7 1.6 0.2 0.2 0.0 2.6 0.8 0.2 0.5 0.1 0.0 0.6 0.3 0.1 0.0 0.1 0.3 0.7 1.1 1.6 1.3 0.8 1.1 1.7 0.1 0.0 0.0 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.0 0.3 0.0 0.0 0.4 0.2 0.4 0.4 0.2 0.2 0.2 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 95.8" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 136.1" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.6;monocytes: 7.1;T-cells: 3.7" "Group enriched" "Detected in some" 6 "MCF7: 10.9;T-47d: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 160000000000 "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 3.6 7.1 0.6 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.9 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 10.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.6 0.7 0.3 2.6 2.4 2.5 0.3 1.6 1.3 0.2 0.0 3.6 3.7 2.5 0.6 7.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 136.1 0.3 0.0 0.0 3.1 1.3 2.5 0.3 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 2.9 0.0 0.0 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 21.3;skin 1: 39.1;vagina: 10.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.5" "Cell type enriched" "Detected in single" 11 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Group enriched" "Detected in some" 15 "HaCaT: 8.8;HDLM-2: 3.5;hTCEpi: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 6.8 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 39.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 10.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 3.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348840 "Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix, uterine: 8.1;skin 1: 19.5;tongue: 13.7;vagina: 8.5" "Cell type enhanced" "Detected in some" 15 "Basal keratinocytes: 1.8;Early spermatids: 1.6;Melanocytes: 1.7;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in some" 9 "cervical cancer: 2.7;head and neck cancer: 7.8;lung cancer: 1.9;melanoma: 1.6;urothelial cancer: 2.0" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "HaCaT: 8.2;HDLM-2: 5.3;hTCEpi: 1.7;Karpas-707: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 8.1 0.0 0.0 0.0 0.1 2.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.2 0.2 0.0 1.5 0.0 0.1 19.5 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 13.7 6.5 0.0 8.5 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 5.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.1 PHKA1 PHKA ENSG00000067177 "Phosphorylase kinase regulatory subunit alpha 1" P46020 X 72578814-72714319 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Muscle protein" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.4" "Cell type enhanced" "Detected in many" 4 "Collecting duct cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14 "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Cell line enhanced" "Detected in many" "HDLM-2: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001081, HPA075355" Enhanced Approved Vesicles,Cytosol NA NA "Vesicles, Cytosol" "HPA001081: AB_1079607, HPA075355: " "unprognostic (3.68e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (6.84e-4)" "unprognostic (3.52e-1)" "unprognostic (5.48e-2)" "unprognostic (1.23e-2)" "unprognostic (9.64e-2)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (2.18e-1)" "unprognostic (4.76e-1)" "unprognostic (9.45e-3)" "unprognostic (9.94e-2)" "unprognostic (2.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" 2.7 10.3 3.8 1.9 7.2 0.7 3.4 3.2 3.5 2.2 2.1 2.0 7.8 1.0 2.7 4.7 4.8 2.8 2.6 5.5 3.0 3.0 2.1 1.8 1.6 1.0 4.2 1.6 5.8 4.2 16.9 14.2 1.8 4.7 4.3 2.5 6.5 6.8 5.1 57.4 2.5 1.3 3.4 3.1 2.3 3.7 3.5 2.7 0.8 6.5 12.6 2.8 3.1 3.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 8.6 12.2 0.7 7.3 4.3 4.1 7.6 1.6 1.5 0.3 0.1 3.5 7.7 0.0 4.9 0.2 8.9 3.4 14.4 5.9 0.4 22.1 14.7 4.0 9.9 3.2 4.5 0.0 0.0 5.5 6.0 1.4 9.9 7.4 8.4 7.3 6.1 0.0 7.9 6.2 6.2 0.4 9.6 14.3 16.3 0.0 0.0 0.0 2.2 4.1 7.6 9.0 7.7 10.1 0.1 9.5 3.6 0.3 4.3 0.0 3.7 1.5 4.2 10.1 9.4 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.2 3.2 2.9 3.0 3.0 4.2 1.6 4.7 2.7 0.0 3.0 0.0 4.0 2.2 1.8 5.6 2.5 6.7 2.3 10.4 7.9 0.8 0.0 1.5 0.3 3.5 0.5 0.0 2.2 0.9 0.5 8.7 5.8 1.5 1.3 3.2 2.4 6.2 6.0 0.0 2.8 0.2 1.7 0.0 2.0 1.3 4.4 0.0 8.1 1.1 2.9 0.0 1.3 0.0 0.7 3.0 0.5 0.0 2.4 7.0 PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892300-18984598 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Hepatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favorable (2.96e-5)" 9.5 8.6 4.0 9.8 8.3 10.8 7.9 10.9 5.9 8.7 7.7 7.8 4.5 10.1 8.5 5.4 5.8 8.3 10.9 8.6 4.2 3.7 6.2 29.4 5.4 14.1 7.1 3.6 14.5 13.1 8.8 16.9 11.6 6.9 8.3 5.2 9.5 7.4 12.4 6.0 6.9 10.1 4.9 6.6 8.5 6.9 12.4 5.4 29.6 9.2 3.4 9.1 7.2 10.4 3.0 3.2 9.9 5.6 4.2 3.4 2.6 8.4 7.9 4.6 7.7 6.3 5.9 13.0 3.7 3.1 5.4 6.0 8.3 5.5 9.8 2.8 4.7 8.6 7.8 8.3 9.5 5.9 4.9 8.7 11.8 12.3 10.0 4.5 11.0 15.2 9.8 6.4 6.6 9.6 9.0 5.6 10.4 3.9 6.1 3.7 8.6 11.5 18.4 5.7 3.8 8.7 9.2 9.6 10.9 3.5 3.7 4.0 6.2 11.3 11.5 5.0 16.2 14.4 6.4 9.9 7.4 4.3 7.9 5.7 6.0 5.0 7.5 4.2 6.0 4.0 5.1 4.6 9.9 3.2 5.6 3.4 2.5 2.6 2.3 3.2 3.0 3.2 3.0 8.2 4.2 3.6 1.7 3.2 2.6 4.0 8.3 10.9 5.9 4.2 3.7 7.1 3.6 6.9 5.4 8.9 14.6 6.2 5.3 5.8 9.7 19.0 15.3 1.4 4.5 8.7 9.8 14.3 0.0 5.1 4.3 5.8 7.7 23.3 4.4 14.6 5.1 5.9 1.1 44.0 6.8 4.8 4.1 19.0 17.6 4.7 6.9 6.4 5.0 1.0 6.5 23.5 6.5 9.5 7.4 3.9 12.4 0.0 3.4 5.4 7.2 4.1 8.8 4.6 11.9 3.3 PHKB ENSG00000102893 "Phosphorylase kinase regulatory subunit beta" Q93100 16 47461123-47701523 "Disease related genes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073380 Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA073380: AB_2686598" "unprognostic (2.87e-3)" "unprognostic (2.41e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.98e-2)" "unprognostic (3.98e-2)" "unprognostic (1.28e-2)" "unprognostic (6.73e-2)" "unprognostic (2.99e-2)" "unprognostic (2.35e-3)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (3.01e-2)" "prognostic favorable (3.89e-9)" "unprognostic (3.56e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (3.24e-4)" "unprognostic (2.53e-2)" 16.9 31.7 11.1 18.1 16.0 11.6 20.6 13.3 16.6 17.2 19.5 16.8 19.5 17.3 22.8 17.6 20.5 12.3 17.0 22.6 11.5 12.4 22.8 16.6 17.0 11.5 14.3 13.0 14.6 21.8 30.0 25.7 17.1 19.9 18.1 19.9 16.1 25.3 21.1 65.6 9.8 24.2 27.0 14.0 17.6 18.5 16.1 10.2 25.2 25.6 23.4 16.3 15.6 15.3 23.1 14.6 12.6 15.6 12.4 11.8 8.7 13.9 20.6 23.7 15.6 16.6 15.8 29.7 16.6 16.1 12.0 6.0 11.2 24.2 16.9 25.1 24.0 9.4 19.8 22.2 25.8 16.9 5.2 11.7 16.0 18.5 37.5 14.8 17.3 19.1 14.1 13.2 8.0 15.1 25.8 23.2 20.8 22.0 10.8 17.2 9.9 16.7 17.1 10.0 23.3 15.8 28.8 29.0 28.5 23.9 12.0 12.5 14.3 27.3 36.6 4.5 27.2 14.0 14.4 25.6 21.8 10.3 11.0 8.7 12.3 9.0 21.9 13.8 11.8 9.0 7.1 15.0 12.6 9.0 13.4 11.8 23.1 9.5 7.3 14.6 23.1 9.5 9.1 7.8 12.4 15.6 10.0 11.0 8.7 11.1 16.0 13.3 16.6 11.5 12.4 14.3 13.0 19.9 10.2 17.9 33.1 36.9 14.7 7.9 32.4 53.8 35.7 20.1 43.3 40.1 94.2 38.8 19.9 17.4 51.2 33.8 39.9 0.0 13.7 21.6 20.6 31.2 17.4 28.1 24.9 22.3 29.3 38.6 50.7 63.4 23.6 27.8 8.5 62.3 34.8 34.7 23.3 20.1 33.6 32.3 71.2 25.8 13.7 50.7 13.0 6.4 28.3 20.3 33.7 23.8 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 105.6;tongue: 32.9" "Cell type enhanced" "Detected in many" 5 "Cholangiocytes: 50.9" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced NA NA "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 2.0 1.5 4.9 0.8 6.1 1.1 1.5 6.0 5.8 0.7 2.6 6.5 0.0 1.0 0.9 1.5 3.2 0.9 1.1 11.8 4.1 2.9 0.6 0.7 0.9 0.8 3.5 3.9 1.0 0.8 1.2 0.6 0.6 6.8 1.4 0.8 0.0 1.6 0.8 105.6 1.6 0.9 1.1 3.6 0.8 0.8 0.7 4.8 0.0 0.6 32.9 1.2 1.8 0.3 1.3 0.6 3.3 0.7 0.3 1.9 0.2 2.9 2.1 0.5 1.8 3.2 5.4 1.4 0.4 0.6 1.0 0.8 0.7 1.3 0.8 0.5 1.0 1.2 1.6 1.2 0.2 0.8 0.8 2.1 0.8 3.0 0.7 0.8 1.5 3.3 3.4 2.3 1.6 0.7 0.8 0.3 2.1 2.2 4.0 0.1 1.3 2.2 5.6 1.0 0.9 1.3 1.2 0.3 1.0 0.6 1.9 1.5 1.6 0.3 2.2 0.1 0.5 1.2 1.9 0.8 0.5 1.7 4.5 1.1 1.8 0.7 2.2 1.2 1.4 1.0 0.4 0.5 0.0 0.8 0.2 1.9 0.3 1.2 0.3 0.2 1.3 0.6 0.6 3.3 0.3 0.7 0.6 0.5 0.2 4.9 6.1 6.0 5.8 4.1 2.9 3.5 3.9 6.8 4.8 11.9 3.4 25.1 6.4 1.1 4.0 1.4 50.9 4.0 6.8 26.2 0.0 6.6 1.7 13.2 2.2 1.4 11.4 23.3 10.9 11.6 6.1 9.6 8.1 41.4 11.0 11.1 16.0 20.9 30.5 5.6 16.7 6.0 1.7 8.2 10.9 4.8 12.7 10.5 15.2 9.0 4.3 12.9 1.0 7.6 9.4 0.9 6.1 8.7 14.4 7.0 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748270-30761176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 44.5;testis: 95.4" "Group enriched" "Detected in many" 6 "Early spermatids: 304.4;Late spermatids: 1171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favorable (7.90e-4)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favorable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favorable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 4.3 8.3 8.7 6.9 8.0 15.9 5.8 9.1 12.0 4.7 7.9 7.3 9.0 6.8 5.6 7.8 5.3 6.8 7.2 6.4 9.0 9.3 8.2 11.0 5.8 6.8 8.6 9.2 4.7 5.1 17.3 8.5 6.3 11.8 7.7 7.6 6.4 7.0 9.9 6.4 8.4 7.3 6.3 5.8 6.9 7.2 95.4 7.3 5.5 8.6 5.5 7.7 5.2 4.7 8.8 21.2 44.5 22.7 23.5 16.8 17.6 13.7 9.0 7.6 9.3 7.1 5.8 17.1 9.6 14.4 13.2 15.1 7.8 6.9 11.9 11.4 9.9 6.7 13.2 7.9 12.2 10.6 6.4 21.9 6.5 15.0 21.8 11.0 10.0 9.3 7.8 6.6 12.6 5.9 6.3 13.4 8.5 8.8 6.9 9.5 31.5 11.8 14.8 10.5 9.9 10.5 16.0 11.9 15.8 15.1 15.5 10.2 7.0 7.8 21.8 9.2 7.2 17.1 8.7 7.9 8.1 9.0 10.1 8.8 13.9 7.5 8.1 16.1 19.6 6.5 14.0 22.7 44.5 16.2 22.4 13.3 8.8 11.6 16.4 21.2 8.5 10.4 12.1 18.2 23.5 15.9 18.2 16.8 17.6 8.7 8.0 9.1 12.0 9.0 9.3 8.6 9.2 11.8 7.3 11.9 23.7 12.6 12.5 18.7 8.9 10.6 2.5 25.4 29.6 17.4 9.8 26.7 23.2 11.4 304.4 9.9 23.2 0.0 21.4 32.3 12.9 24.0 12.7 19.5 25.4 19.1 15.6 9.2 22.4 1171.9 16.1 24.0 11.8 42.3 15.6 9.8 16.8 15.0 21.9 32.7 8.4 0.0 12.5 127.4 23.3 20.1 63.2 26.2 19.6 12.4 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715450-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.0" "Cell type enhanced" "Detected in many" 8 "Muller glia cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 7.7;T-reg: 2.4" "Group enriched" "Detected in many" 7 "granulocytes: 7.7;T-cells: 2.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Uncertain "Intracellular and membrane" NA NA "HPA020200: AB_2670383" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favorable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.8 10.6 22.1 2.3 34.1 7.4 7.4 8.3 29.6 4.3 6.0 48.0 0.9 6.2 4.4 2.5 6.1 4.0 4.9 3.0 22.4 12.3 4.0 18.5 3.4 3.0 44.4 13.8 5.5 8.0 9.6 5.6 6.3 20.6 5.0 6.7 4.4 11.2 4.5 3.9 9.1 5.5 4.0 18.6 2.0 5.6 11.5 44.8 2.3 5.6 1.6 4.1 5.6 3.2 0.6 0.7 7.7 0.2 0.6 2.4 0.1 9.0 3.4 14.0 4.6 2.4 2.0 10.9 2.7 2.5 5.4 5.6 7.4 5.5 6.1 1.7 4.1 2.1 11.1 7.2 4.3 7.0 18.8 6.0 2.0 3.7 13.7 3.4 3.1 1.0 2.1 2.9 5.8 5.3 4.4 3.8 3.3 5.2 12.3 5.2 2.0 2.3 2.7 5.6 1.8 3.3 21.7 7.9 7.3 3.1 11.8 6.5 2.6 3.0 6.8 5.6 8.5 3.0 8.9 4.8 4.5 2.1 2.6 6.3 1.4 0.7 7.2 2.6 3.6 3.4 0.0 0.2 0.1 0.7 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.4 0.1 7.7 0.6 0.2 0.3 2.4 0.1 22.1 34.1 8.3 21.1 22.4 12.3 44.4 13.8 20.6 44.8 3.0 1.0 0.0 3.7 14.9 14.8 3.3 15.3 8.1 5.7 0.0 27.5 10.8 1.7 2.5 26.9 5.8 5.6 0.0 3.6 4.7 6.0 6.4 2.3 16.3 2.1 25.4 11.6 6.2 2.8 24.6 5.5 4.6 23.6 3.6 7.9 82.5 3.7 5.8 3.5 1.8 16.7 0.0 4.4 5.0 16.9 16.3 21.9 0.0 11.5 7.4 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 29.9" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 98.2;Enterocytes: 51.9;Rod photoreceptor cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" NA No Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 6.4 4.7 12.5 7.0 10.9 8.1 8.4 17.4 14.9 4.4 16.6 4.6 4.3 15.8 5.8 4.9 2.7 4.7 4.1 4.6 11.7 9.0 5.4 4.9 4.8 5.0 6.2 14.9 7.2 4.9 10.2 7.3 4.3 12.6 4.7 17.8 13.2 2.9 5.7 5.3 3.0 29.9 7.0 7.6 3.9 4.2 10.8 4.7 1.0 9.9 1.1 4.9 4.7 9.8 2.4 2.2 1.2 0.7 3.5 1.5 0.4 4.9 6.5 7.1 7.9 5.7 6.9 4.1 7.4 6.7 10.7 8.8 5.9 1.6 9.8 2.9 12.2 7.7 10.5 10.2 3.8 13.9 3.4 5.5 2.7 5.6 3.9 4.5 2.3 4.3 5.1 2.2 15.2 5.0 4.5 4.0 3.4 2.4 2.7 7.4 10.4 3.2 1.8 5.5 1.5 1.7 5.1 6.2 3.2 5.1 3.8 6.2 3.3 15.9 4.4 2.6 5.7 5.4 1.4 5.5 10.8 7.8 4.5 6.1 6.1 4.3 10.1 6.7 1.9 2.4 0.8 0.5 0.2 1.0 0.7 0.9 2.4 0.8 1.5 0.6 1.6 1.1 0.9 1.2 3.5 0.7 2.2 1.3 0.4 12.5 10.9 17.4 14.9 11.7 9.0 6.2 14.9 12.6 4.7 8.9 2.1 5.2 4.7 8.2 18.7 2.3 0.0 2.7 4.5 3.5 98.2 3.8 0.0 2.4 9.7 3.7 51.9 0.0 2.0 0.3 7.2 5.0 10.3 3.9 1.3 22.3 5.8 3.1 5.4 3.6 4.9 2.2 13.5 2.8 6.7 6.3 2.8 31.6 4.9 4.3 60.3 6.5 5.6 29.1 18.3 8.0 1.1 3.5 7.2 2.1 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208497-178232791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Lyase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 190000 Mitochondria "HPA036461: AB_10670717, HPA063608: AB_2685059" "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavorable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 18.7 13.1 10.5 25.0 10.8 9.8 15.5 8.3 10.9 13.9 24.3 13.4 14.4 15.1 13.5 14.9 10.7 13.6 17.5 15.5 8.9 4.9 18.1 44.4 14.7 16.8 13.7 9.3 13.2 18.0 11.9 11.9 11.8 10.2 12.4 23.9 12.1 12.3 13.7 20.2 7.6 29.8 14.1 10.7 20.2 15.3 16.4 11.7 16.3 16.6 10.5 17.4 14.0 11.8 13.9 32.8 16.7 21.7 10.7 14.0 14.3 5.8 2.4 5.8 2.3 14.7 11.7 8.8 3.7 4.1 4.9 7.9 6.2 7.5 7.6 11.2 11.2 6.2 3.8 5.0 9.4 5.7 15.6 5.0 9.7 9.8 4.4 23.9 5.5 6.3 13.3 9.9 6.2 15.1 10.1 16.3 11.4 7.1 17.7 7.4 8.5 7.7 2.9 1.2 7.3 8.0 5.1 2.8 15.3 8.9 5.3 3.6 3.3 5.8 3.4 6.1 7.1 3.7 4.5 6.6 5.1 4.6 3.3 3.9 11.3 3.1 4.6 1.5 5.9 3.4 6.3 19.5 16.7 10.0 21.7 10.1 13.9 11.3 11.4 25.2 12.6 14.0 11.3 4.4 10.7 21.3 32.8 12.9 14.3 10.5 10.8 8.3 10.9 8.9 4.9 13.7 9.3 10.2 11.7 17.9 14.7 36.2 35.3 9.5 20.4 15.7 33.1 12.0 9.1 22.7 23.6 14.0 16.6 17.9 16.8 22.4 97.5 0.0 16.2 15.1 23.7 24.7 12.7 27.6 27.2 14.3 18.5 22.7 23.8 45.2 39.4 30.7 23.6 63.1 33.9 26.4 14.7 54.6 23.7 31.0 26.5 12.9 16.5 28.6 23.7 9.2 18.4 34.6 33.9 31.3 PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678935-130746829 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved Vesicles,Microtubules NA NA Vesicles Microtubules "HPA036032: AB_10610281, HPA036033: AB_2674911" "unprognostic (7.50e-2)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (4.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.02e-3)" "unprognostic (7.26e-2)" "prognostic favorable (4.40e-6)" "unprognostic (8.25e-2)" "unprognostic (3.72e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" 15.5 16.2 11.6 11.6 15.9 10.6 14.9 14.7 17.2 16.5 13.1 14.9 9.5 10.3 18.8 12.0 12.9 15.6 12.0 12.2 9.7 10.0 14.9 28.2 13.7 12.4 12.0 11.4 17.8 12.0 40.7 20.6 14.4 17.3 14.1 11.6 14.1 14.0 15.4 14.8 16.0 13.4 14.6 12.1 18.5 13.3 14.9 11.8 29.7 18.1 10.2 13.6 16.5 13.9 8.4 9.6 12.0 8.5 11.5 13.7 7.0 14.3 9.1 13.4 9.7 19.9 15.9 9.3 10.7 12.9 14.8 17.2 11.8 12.2 16.9 13.5 10.8 11.8 20.6 22.0 16.6 23.3 10.2 8.2 13.8 10.5 8.2 9.1 20.9 6.9 10.9 12.0 15.8 10.0 9.3 13.7 9.9 16.0 8.6 13.0 12.6 17.1 6.4 16.9 13.0 9.0 12.0 15.6 15.2 9.7 11.8 12.4 9.1 15.4 9.7 10.8 16.5 13.4 9.2 10.8 11.4 9.9 12.8 8.5 10.1 9.1 22.3 12.5 8.0 10.5 12.0 7.2 9.2 9.4 8.4 13.7 8.4 8.6 6.9 9.6 5.7 10.1 9.0 6.0 11.5 8.5 3.4 9.3 7.0 11.6 15.9 14.7 17.2 9.7 10.0 12.0 11.4 17.3 11.8 6.0 5.4 0.0 3.4 3.4 8.2 7.5 15.3 14.7 11.4 10.4 13.7 4.6 1.7 4.1 3.4 6.7 5.3 0.0 5.1 3.1 3.5 3.7 9.2 15.6 5.1 4.8 2.9 8.0 6.7 2.7 8.9 3.8 5.0 5.4 6.2 8.0 5.3 5.8 11.0 4.9 12.0 6.5 3.2 10.8 12.7 3.9 3.5 4.6 5.8 2.5 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170203-37175426 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Suprabasal keratinocytes: 199.7;Urothelial cells: 399.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 64.6" "Group enriched" "Detected in all" 5 "granulocytes: 64.6;T-cells: 19.0" "Cell line enhanced" "Detected in many" "HEL: 35.7;HMC-1: 66.4;K-562: 30.6;U-698: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoli,Cytosol NA NA Cytosol Nucleoli "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 39.3 5.4 7.4 18.5 8.9 80.9 20.1 8.1 9.9 23.0 17.9 4.7 4.2 17.9 15.4 9.8 56.3 21.6 24.7 20.8 8.2 3.7 7.5 24.5 14.5 35.7 7.4 2.2 20.0 9.6 2.0 5.6 28.7 12.7 15.6 8.8 6.9 12.8 4.5 26.5 31.3 26.1 31.6 10.7 21.4 12.1 6.8 7.6 15.0 7.2 20.1 28.8 32.6 31.2 1.7 1.4 64.6 1.7 8.4 19.0 8.5 3.0 1.3 2.0 1.1 4.7 2.5 24.0 1.1 3.4 2.3 3.6 4.6 4.3 6.2 1.7 1.3 5.1 3.6 2.1 3.3 2.1 28.1 1.4 35.7 1.3 5.9 4.8 0.6 66.4 8.5 4.1 2.1 1.4 2.5 0.6 1.5 30.6 10.0 0.3 0.8 1.9 3.2 3.8 5.7 2.0 4.8 3.7 7.3 0.6 18.8 10.0 2.0 2.4 0.3 0.6 4.9 0.5 1.0 1.2 1.3 4.0 6.0 1.3 4.7 2.5 119.4 0.5 9.0 1.3 64.6 1.7 24.4 14.7 1.6 19.0 1.7 13.1 12.9 1.4 1.3 11.9 9.0 14.1 8.4 0.9 0.4 9.4 8.5 7.4 8.9 8.1 9.9 8.2 3.7 7.4 2.2 12.7 7.6 20.8 23.1 27.2 134.9 113.6 4.2 17.3 12.7 4.0 22.7 8.7 0.0 27.3 5.0 30.7 3.8 14.3 33.2 46.7 15.5 92.9 73.9 69.5 46.4 27.1 44.8 14.3 35.6 9.2 40.0 10.4 7.5 45.8 42.2 101.0 11.9 4.3 37.7 17.5 2.8 13.0 0.9 0.0 57.5 3.3 34.5 199.7 67.5 126.4 6.6 399.5 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 63.4;lymphoid tissue: 71.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 48.0;B-cells: 109.2;Melanocytes: 89.4;monocytes: 163.3;T-cells: 70.8" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HDLM-2: 60.3;Karpas-707: 74.7;RPMI-8226: 73.6;U-266/70: 136.0;U-266/84: 120.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favorable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 3.6 3.4 4.3 37.2 7.2 30.4 3.4 7.1 7.9 4.5 13.4 2.1 2.2 29.5 2.8 4.3 10.0 5.6 8.3 3.1 5.6 6.7 5.2 5.4 10.6 59.7 3.8 4.6 5.4 3.0 1.0 4.9 2.4 6.7 3.6 17.7 6.1 16.9 4.9 1.5 3.0 19.2 2.2 3.1 71.2 14.7 5.7 1.3 39.4 4.8 3.6 47.9 24.6 3.3 26.0 2.9 46.9 3.0 17.0 63.4 13.2 1.8 1.6 0.8 1.7 0.3 0.2 1.3 1.1 1.4 1.6 1.4 1.4 1.4 8.0 0.5 0.5 0.6 1.1 2.7 1.0 1.5 60.3 2.1 9.7 1.6 1.4 0.7 2.3 6.5 0.6 0.9 1.7 1.0 1.3 0.6 1.0 10.2 74.7 0.9 1.3 0.8 4.8 18.2 0.6 2.5 1.0 0.6 73.6 1.6 0.2 0.6 0.8 1.2 0.8 0.8 4.3 2.1 3.1 0.3 0.4 0.2 0.3 1.1 136.0 120.2 15.3 1.5 2.0 0.4 46.9 1.5 14.3 12.5 1.9 21.2 26.0 34.4 17.6 2.5 15.9 36.9 23.0 38.3 17.0 3.0 2.9 63.4 13.2 4.3 7.2 7.1 7.9 5.6 6.7 3.8 4.6 6.7 1.3 11.9 48.0 109.2 9.5 18.0 2.3 2.0 0.0 14.7 12.5 3.5 2.0 5.3 3.3 2.8 1.4 4.3 4.0 0.0 3.1 5.0 7.5 4.0 22.0 5.4 6.3 11.1 12.6 3.1 9.1 1.4 1.7 18.6 89.4 163.3 6.6 2.3 1.6 3.5 3.9 5.4 2.2 0.0 8.1 2.1 1.5 12.0 2.1 70.8 8.1 3.9 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Syncytiotrophoblasts: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 46.5;SK-BR-3: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.3 4.9 3.3 6.2 2.6 1.9 18.9 4.6 7.5 5.6 4.0 8.1 6.3 13.2 5.9 1.2 11.3 6.3 6.3 3.5 2.0 9.9 26.2 5.4 11.7 9.8 12.2 11.7 10.5 3.7 11.7 3.4 5.8 3.0 18.0 9.0 7.4 46.5 1.6 16.5 5.9 20.9 6.9 7.7 7.9 27.7 5.5 15.6 2.9 5.6 11.8 8.2 9.0 41.3 28.9 3.2 5.4 15.6 4.7 3.5 15.0 5.7 7.5 23.9 15.2 11.2 8.7 6.6 9.4 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 59.6 91.3 64.7 240.2 201.8 30.4 27.9 68.8 20.1 45.5 76.8 2.0 51.0 71.3 44.7 2.1 87.2 56.5 0.0 46.7 226.7 51.4 225.9 70.2 37.5 64.3 58.8 93.7 59.5 30.8 4.1 30.0 74.6 102.9 46.9 56.5 11.1 57.1 46.3 10.6 48.8 15.3 25.8 117.4 19.9 37.3 178.9 326.1 26.6 49.6 261.0 PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849682 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 88.2" "Cell type enhanced" "Detected in all" 7 "Late spermatids: 571.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 30000 Nucleoplasm Cytosol "CAB004528: AB_628132, CAB009326: AB_2237080, HPA068650: AB_2686014, HPA070887: " "unprognostic (2.54e-1)" "unprognostic (6.14e-3)" "unprognostic (6.50e-2)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (6.50e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (2.67e-1)" "unprognostic (7.23e-3)" "prognostic favorable (3.25e-4)" "unprognostic (9.43e-2)" "prognostic favorable (7.80e-5)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.21e-2)" 24.5 36.3 40.0 18.7 38.8 25.6 9.3 27.4 66.0 9.2 15.8 18.1 8.5 22.9 14.0 8.3 11.3 16.4 10.1 25.9 38.0 35.2 17.4 14.5 13.2 14.8 38.7 37.2 13.9 21.1 9.5 13.6 13.3 57.3 23.2 6.5 14.1 21.3 15.7 50.2 10.2 21.7 11.1 19.6 15.4 19.6 24.8 15.0 19.7 9.9 8.1 9.3 11.1 9.7 36.4 72.8 88.2 44.9 40.7 53.8 46.2 26.2 24.1 18.0 16.7 6.3 5.6 10.6 19.7 8.5 14.7 14.2 22.3 8.4 16.3 31.4 7.3 15.3 13.5 12.4 11.9 4.7 34.7 52.6 42.4 29.6 19.2 10.3 19.7 24.9 7.7 8.0 9.5 4.5 11.0 11.9 29.3 19.1 24.8 8.8 18.4 29.9 77.2 17.2 11.0 37.1 27.4 18.7 27.3 10.5 12.9 22.7 26.7 19.0 9.5 22.0 7.7 12.2 23.7 20.1 20.4 16.3 31.5 31.5 32.1 30.1 21.9 21.7 25.3 25.0 52.2 43.4 88.2 42.0 44.9 39.2 35.6 41.5 42.1 39.7 36.4 33.1 37.2 26.8 40.7 41.7 72.8 53.8 46.2 40.0 38.8 27.4 66.0 38.0 35.2 38.7 37.2 57.3 15.0 26.8 21.5 49.1 53.7 42.8 68.5 65.3 43.3 56.2 14.8 59.3 11.8 107.3 139.3 95.7 197.0 54.9 69.5 46.7 95.4 80.4 81.4 55.2 63.4 41.4 123.0 57.2 95.8 47.3 50.0 571.0 83.4 67.4 118.1 174.1 57.9 60.8 85.6 73.7 122.0 109.4 50.6 64.7 97.1 136.8 72.0 57.6 46.0 94.4 62.6 47.8 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 68.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: AB_2682503, HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favorable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favorable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favorable (2.66e-4)" 14.4 11.3 15.0 8.0 14.7 6.1 18.8 10.7 16.2 9.7 9.7 8.4 6.7 9.5 11.6 19.3 8.9 8.7 30.7 11.2 15.2 12.2 15.6 23.2 7.9 7.9 12.9 11.0 12.7 8.1 8.0 9.2 9.8 10.0 10.4 11.1 6.6 30.7 37.1 68.7 7.3 9.6 9.2 12.4 16.7 9.3 4.7 6.9 9.7 12.9 40.1 9.1 7.8 9.2 28.9 26.8 23.4 23.6 22.4 33.4 22.7 15.4 18.1 19.0 12.9 13.0 10.9 10.1 10.6 12.2 13.0 13.4 9.1 11.5 4.6 31.0 10.9 17.6 11.0 16.8 18.6 16.1 11.7 37.8 7.9 21.6 23.9 7.2 12.5 6.7 7.3 10.3 14.2 4.9 14.7 13.2 14.2 13.3 20.6 9.7 18.7 10.9 21.1 13.5 17.6 16.4 10.9 15.1 13.7 16.5 10.8 12.2 21.7 12.4 5.8 10.9 14.6 9.0 11.5 13.2 5.9 9.1 16.2 7.7 7.1 7.6 7.7 17.0 12.6 6.4 21.9 23.3 23.4 26.8 23.6 26.4 28.9 28.3 25.5 22.8 26.4 29.3 29.4 9.7 22.4 21.8 26.8 33.4 22.7 15.0 14.7 10.7 16.2 15.2 12.2 12.9 11.0 10.0 6.9 62.5 35.0 52.8 54.1 38.4 26.9 74.7 81.5 84.3 51.2 113.4 7.9 137.4 154.2 102.6 10.6 70.5 117.6 23.3 102.2 92.0 70.9 50.1 55.5 238.7 95.4 27.0 88.9 80.4 73.2 6.2 69.0 61.7 57.3 68.5 76.9 55.6 124.5 101.7 76.4 218.0 33.7 84.1 78.3 14.4 39.1 40.9 100.9 62.3 82.1 54.0 PINK1 PARK6 ENSG00000158828 "PTEN induced putative kinase 1" Q9BXM7 1 20633455-20651511 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.7" "Group enriched" "Detected in many" 4 "granulocytes: 10.7;monocytes: 4.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Enhanced NA NA "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 17.9 35.9 38.9 6.7 38.0 6.0 10.1 16.8 45.0 9.8 13.0 17.8 10.0 15.2 9.3 9.8 20.7 10.7 11.4 51.4 31.0 28.7 20.2 26.1 10.0 5.1 39.5 27.1 11.6 24.3 16.3 7.1 13.9 31.0 12.4 7.7 10.6 23.9 15.4 142.0 10.8 12.7 10.8 30.2 8.3 10.5 27.2 16.8 3.3 16.0 21.5 4.6 12.7 9.5 1.2 1.4 10.7 4.4 0.7 1.7 0.8 17.7 8.1 3.8 11.0 13.3 12.6 4.0 25.1 25.2 12.2 21.3 2.8 14.5 4.2 19.9 25.5 28.4 8.2 5.5 13.3 6.1 5.0 21.0 2.1 22.7 4.3 10.3 2.2 6.7 11.8 14.4 15.2 5.3 13.7 7.9 3.9 5.1 5.4 8.7 7.5 3.2 5.0 1.7 4.6 26.8 2.8 6.7 3.3 7.6 4.2 14.2 5.5 27.3 9.0 7.6 4.8 3.0 7.8 11.9 11.0 5.7 18.4 3.5 6.3 1.2 1.9 23.9 6.4 5.1 4.8 2.2 4.7 1.1 1.4 1.4 0.3 1.0 1.5 0.7 1.2 0.8 1.1 10.7 0.7 4.4 1.4 1.7 0.8 38.9 38.0 16.8 45.0 31.0 28.7 39.5 27.1 31.0 16.8 20.8 16.3 7.5 31.9 14.0 40.7 0.8 28.1 1.4 6.8 41.8 35.3 21.6 68.0 22.2 58.2 29.5 63.2 23.3 24.0 29.3 21.6 60.4 0.0 92.6 20.3 27.0 19.3 46.6 19.9 102.1 32.8 20.6 20.3 4.6 26.4 52.6 41.8 45.6 53.4 91.3 57.1 84.1 37.3 110.5 24.5 21.0 28.6 13.1 18.0 30.8 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 98.7" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 12.6 9.9 21.6 5.5 35.7 2.6 7.9 13.4 23.7 12.2 5.8 8.9 19.3 4.7 9.2 98.7 5.7 10.2 7.1 7.5 18.4 23.4 7.5 4.4 7.4 5.9 14.9 16.7 16.2 6.0 27.1 12.5 10.7 11.7 9.9 5.3 7.2 6.4 20.3 4.7 7.1 4.4 9.8 12.0 5.9 6.5 13.7 9.5 3.0 13.8 2.9 7.4 7.8 7.9 11.2 4.3 2.7 4.5 14.8 17.8 9.0 10.4 8.0 25.1 17.6 8.8 9.3 7.6 7.0 8.4 6.6 8.9 6.5 9.9 1.6 10.9 11.1 15.6 9.1 38.6 13.7 8.3 7.8 13.7 3.1 6.6 4.3 11.0 1.8 6.0 9.7 9.1 11.3 6.7 6.4 7.4 5.3 2.9 1.1 6.7 5.6 0.8 3.6 17.1 8.9 13.2 7.5 11.2 2.5 10.6 8.8 18.7 12.1 11.2 1.9 8.5 20.9 3.1 2.6 6.7 5.7 9.2 16.9 3.2 0.0 0.1 3.8 6.2 5.1 7.6 2.7 3.3 1.0 15.5 4.5 17.8 8.7 13.7 14.2 3.6 11.2 14.4 16.6 1.1 14.8 2.9 4.3 8.3 9.0 21.6 35.7 13.4 23.7 18.4 23.4 14.9 16.7 11.7 9.5 14.9 4.5 5.1 14.7 36.5 16.4 6.3 5.1 2.7 11.4 3.5 7.9 30.0 13.3 20.5 77.4 5.1 0.7 0.0 10.2 12.8 18.9 7.8 4.6 1.7 6.7 4.8 5.2 5.5 3.8 22.6 25.0 4.1 5.0 1.8 2.8 28.6 13.9 1.4 18.4 4.4 5.9 6.5 17.0 0.9 1.0 25.7 17.4 7.9 2.3 17.6 PJA2 "KIAA0438, Neurodap1, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334709-109409994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040347, HPA057636" Supported Enhanced "Intermediate filaments" No No "Intermediate filaments" "HPA040347: AB_10795631, HPA057636: AB_2683485" "unprognostic (5.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.48e-3)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (7.83e-2)" "unprognostic (2.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.84e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (4.46e-2)" "unprognostic (6.03e-2)" "unprognostic (5.64e-3)" "unprognostic (1.47e-3)" "unprognostic (5.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.00e-2)" 21.6 27.0 40.1 15.9 49.9 29.0 22.1 41.6 63.0 29.0 23.8 19.7 16.8 12.5 29.2 25.0 20.7 20.3 18.6 24.4 44.3 46.2 24.1 29.2 19.4 14.3 36.8 44.0 35.4 14.8 42.8 30.3 21.8 53.2 31.7 20.6 12.5 17.3 37.7 17.1 13.6 15.9 39.2 37.6 19.5 15.8 17.0 27.4 16.7 35.9 9.7 16.3 35.5 21.4 10.3 11.7 29.9 15.5 10.7 12.2 10.6 11.8 8.2 33.3 25.6 33.1 36.3 18.1 19.6 29.6 15.5 25.5 7.6 16.2 15.3 27.2 37.6 25.0 6.9 19.4 24.1 28.5 13.0 7.3 17.7 16.9 10.3 23.5 13.2 26.3 25.0 20.2 20.7 29.9 27.9 24.7 13.8 12.1 28.9 25.0 7.2 15.8 12.2 6.6 7.3 5.5 10.3 29.3 25.5 24.1 10.7 6.4 16.4 20.2 7.4 23.6 23.3 16.7 19.6 28.4 22.1 10.8 20.3 9.1 19.5 16.6 18.2 23.4 18.4 14.5 17.3 11.6 17.3 9.5 12.2 9.4 10.3 9.4 8.7 11.7 7.4 12.1 8.9 29.9 10.7 15.5 4.9 12.2 10.6 40.1 49.9 41.6 63.0 44.3 46.2 36.8 44.0 53.2 27.4 62.5 47.1 47.1 45.8 56.3 93.5 116.8 50.9 41.5 45.5 54.1 58.9 19.9 41.4 32.7 16.4 64.5 53.5 0.0 28.7 23.4 57.5 66.5 46.2 90.1 46.6 73.1 64.9 65.1 78.4 15.1 78.9 53.7 57.3 31.5 47.8 99.2 29.4 20.1 87.0 45.1 78.2 77.6 80.4 73.2 30.2 50.8 22.0 50.7 29.6 32.0 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980539 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.5;lymphoid tissue: 42.8;testis: 61.4" "Group enriched" "Detected in many" 6 "Extravillous trophoblasts: 39.8;Spermatocytes: 108.0;Spermatogonia: 40.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 4.4" "Lineage enriched" "Detected in single" 5 "T-cells: 4.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 0.9 0.7 0.7 9.4 0.6 19.5 1.3 2.6 0.8 1.3 2.9 0.3 0.5 1.9 0.8 1.5 7.2 0.2 1.5 1.4 0.7 0.7 0.8 1.0 1.3 6.2 0.8 0.2 0.3 1.3 0.0 0.7 4.3 0.4 0.6 0.8 0.3 1.3 0.2 1.6 3.4 3.2 0.6 1.0 4.4 2.7 61.4 0.2 42.8 0.3 9.2 12.7 0.7 2.0 0.8 0.4 0.3 0.5 0.4 4.4 1.0 24.9 17.5 6.8 9.8 0.1 0.3 18.6 19.4 4.6 12.3 11.8 13.6 14.8 15.6 8.7 2.1 7.3 32.1 4.8 6.2 2.2 20.0 15.7 7.9 15.8 11.9 0.0 8.8 22.5 0.2 0.5 7.3 2.0 1.5 2.5 17.3 22.7 27.7 4.0 37.4 24.6 24.5 11.2 11.7 9.3 26.9 15.3 30.2 2.3 5.5 13.0 13.8 9.4 24.5 7.3 3.9 14.0 17.6 2.3 16.6 21.0 24.2 20.3 21.0 15.6 26.8 6.3 11.8 19.2 0.0 0.4 0.3 0.3 0.3 0.0 0.8 0.5 0.5 0.4 0.0 0.0 0.0 0.1 0.4 0.5 0.1 4.4 1.0 0.7 0.6 2.6 0.8 0.7 0.7 0.8 0.2 0.4 0.2 0.0 1.4 0.0 0.8 2.3 0.1 0.4 2.5 0.0 2.3 1.8 5.9 3.0 0.0 1.1 11.2 0.3 0.2 0.0 0.5 39.8 0.4 0.5 0.0 0.2 10.2 0.0 1.7 0.0 1.3 7.5 0.3 1.3 0.0 1.0 1.2 0.3 0.3 0.0 0.4 0.0 6.7 0.0 0.0 108.0 40.5 0.5 6.2 0.7 3.5 0.4 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Focal adhesion sites,Cytokinetic bridge" NA NA "Plasma membrane" "Focal adhesion sites, Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 28.8 19.5 19.1 27.6 26.7 39.6 25.3 21.9 19.2 19.2 26.0 20.9 16.5 10.0 25.4 19.7 16.6 22.2 22.5 38.3 17.1 17.6 17.9 16.3 27.9 42.2 19.5 16.3 21.7 32.3 15.8 18.7 22.7 19.2 22.6 6.9 21.5 22.6 22.7 43.2 7.6 16.9 22.5 19.4 39.7 24.2 21.5 18.9 39.2 17.8 13.8 24.0 22.1 30.5 11.5 17.0 24.1 30.6 13.5 20.7 15.2 37.7 22.5 8.4 17.4 13.6 16.1 13.8 13.6 16.3 14.4 13.8 8.8 21.7 36.1 35.2 23.3 18.0 8.8 13.4 6.0 5.6 29.2 17.4 43.2 14.4 18.6 45.1 17.0 27.1 11.5 4.4 8.7 13.7 16.4 33.4 19.2 19.1 25.1 10.6 15.5 25.5 15.7 15.2 13.7 25.8 34.3 11.5 25.9 7.1 6.2 30.6 43.4 8.4 10.8 22.0 4.2 9.7 29.6 49.9 28.6 12.3 34.6 20.6 33.0 30.0 19.7 18.8 34.1 22.4 15.4 17.3 24.1 20.7 24.2 15.7 10.7 14.0 14.2 17.0 11.5 13.1 14.3 21.3 13.5 30.6 11.1 15.9 15.2 19.1 26.7 21.9 17.3 17.1 17.6 19.5 16.3 19.2 18.9 3.0 2.1 24.5 5.5 3.3 36.7 3.5 25.5 1.4 1.2 33.2 15.7 1.9 1.7 23.7 4.1 29.5 2.6 0.0 25.6 12.9 16.0 10.2 2.3 9.6 49.5 46.1 38.6 51.0 56.2 6.7 18.4 27.1 16.9 29.7 12.0 47.4 49.8 9.5 21.5 12.7 25.3 25.8 16.5 6.3 26.6 2.4 3.1 48.4 6.6 3.2 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 35.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 35.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 21.9 20.7 12.2 21.2 13.7 33.5 27.6 25.6 16.6 28.6 39.3 12.6 15.1 22.9 20.0 20.2 28.2 17.1 13.3 16.2 10.3 8.9 15.9 15.9 26.0 16.4 13.7 8.7 27.2 18.9 24.6 29.7 20.8 13.3 19.6 23.6 14.1 19.5 25.1 15.9 17.5 49.0 17.5 12.5 18.0 15.9 12.4 16.2 29.1 20.3 14.4 13.1 21.9 22.0 4.0 3.7 35.7 4.5 1.4 3.0 1.0 23.7 9.3 18.5 11.1 12.4 14.1 12.0 14.1 13.0 15.8 16.5 9.9 17.1 9.4 16.8 13.4 19.5 18.8 18.0 10.7 21.7 3.3 13.1 6.9 19.4 8.4 10.9 6.8 2.1 11.6 11.1 12.4 15.0 12.6 18.0 7.5 11.5 6.9 17.0 4.8 7.8 5.9 9.3 9.0 10.9 7.5 28.2 3.8 14.0 46.8 9.0 5.9 21.1 12.2 18.1 14.6 9.1 6.2 16.8 13.5 12.1 17.2 14.7 3.8 3.2 6.4 5.6 6.7 5.0 4.9 4.5 6.8 2.6 2.5 2.3 3.3 2.3 2.4 2.1 4.0 3.0 2.6 35.7 1.4 3.2 3.7 1.8 1.0 12.2 13.7 25.6 16.6 10.3 8.9 13.7 8.7 13.3 16.2 38.7 52.6 24.5 42.6 42.9 83.6 41.1 40.8 45.5 39.8 66.3 84.4 37.5 10.0 51.4 2.1 51.2 79.8 70.0 52.5 29.4 35.1 52.3 15.1 32.6 20.4 62.0 42.5 51.0 34.3 2.9 50.3 29.0 30.4 41.5 55.9 64.3 62.0 87.7 45.3 22.4 151.6 38.8 29.8 35.8 18.8 45.8 31.2 21.0 50.9 118.4 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702523-128720918 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Endothelial cells: 13.4;Extravillous trophoblasts: 5.1;Ito cells: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 33.4;REH: 20.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 11.4 1.8 1.5 6.8 3.8 3.7 10.5 10.1 3.9 4.3 5.8 3.7 4.8 7.7 9.7 2.2 7.1 5.3 10.9 7.3 2.3 1.7 5.0 6.4 8.9 9.1 3.9 1.2 4.0 4.2 3.3 1.4 5.6 4.5 4.2 1.6 4.1 12.9 3.7 7.4 6.7 5.4 4.9 4.4 7.8 7.4 4.3 1.7 9.3 8.1 6.1 5.9 4.4 5.0 0.4 1.0 2.3 0.7 1.0 1.8 0.3 1.4 6.9 5.6 8.5 0.0 0.1 13.9 4.3 1.3 6.3 6.5 0.0 5.0 0.0 4.2 2.3 1.3 9.3 6.8 1.0 1.4 4.3 12.8 8.2 33.4 9.7 1.0 1.0 1.5 0.3 0.3 3.4 0.9 1.3 12.4 2.5 18.6 0.9 1.1 12.8 1.2 4.4 5.2 6.3 2.0 20.3 10.6 1.8 2.6 0.8 0.9 4.2 3.2 1.7 3.2 3.2 6.1 6.6 10.7 0.0 5.3 9.9 3.2 3.1 1.3 2.7 0.8 1.0 3.9 0.0 0.1 1.4 0.9 0.7 1.8 0.2 0.6 0.8 1.0 0.4 0.8 0.1 2.3 1.0 0.2 0.2 1.0 0.3 1.5 3.8 10.1 3.9 2.3 1.7 3.9 1.2 4.5 1.7 0.0 1.3 0.0 1.4 0.9 0.0 1.5 0.0 0.0 2.3 0.0 0.0 1.2 0.0 1.6 0.3 13.4 1.1 0.0 2.3 5.1 0.9 0.9 0.0 0.2 1.5 0.0 0.0 6.2 0.3 0.4 1.4 0.2 0.0 1.8 1.0 0.5 2.6 0.8 0.7 0.3 0.2 0.0 0.8 1.0 3.4 0.9 1.1 1.0 1.4 1.6 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 83.9;testis: 32.4" "Cell type enhanced" "Detected in many" 18 "Early spermatids: 86.9;Erythroid cells: 23.3;Extravillous trophoblasts: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "T-reg: 9.0" "Lineage enriched" "Detected in many" 5 "T-cells: 9.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA051638, HPA053229" Approved NA Yes "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 2.9 1.1 1.1 14.2 1.5 15.9 1.7 2.1 1.1 1.5 7.1 0.7 0.5 6.0 1.1 0.9 10.4 0.7 1.5 1.0 1.0 0.8 1.3 1.2 2.6 15.2 0.8 0.6 1.2 0.7 0.0 0.8 6.8 0.7 0.9 5.9 0.5 1.7 0.8 0.8 2.9 5.9 2.0 0.7 8.3 3.6 32.4 0.5 83.9 0.6 6.6 20.4 2.1 2.6 1.9 0.5 0.7 0.1 1.3 9.0 2.3 43.5 45.5 37.6 20.4 1.1 2.6 21.1 24.9 16.5 39.1 29.1 39.7 28.8 21.8 13.0 16.8 20.6 25.1 51.2 20.5 47.1 31.0 28.9 27.7 35.9 54.2 0.3 31.9 30.4 1.0 1.1 27.7 28.6 4.9 28.5 28.6 43.0 30.1 30.1 39.8 30.1 31.9 42.9 17.9 23.2 46.9 25.5 34.6 11.1 9.5 21.2 14.7 28.5 20.0 12.9 22.4 25.4 19.7 14.4 18.6 23.8 18.2 42.5 21.5 33.3 37.8 15.8 27.8 30.4 0.0 0.1 0.0 0.0 0.0 0.0 1.9 1.4 0.5 0.5 0.0 0.0 0.0 0.7 1.3 0.0 0.0 9.0 2.3 1.1 1.5 2.1 1.1 1.0 0.8 0.8 0.6 0.7 0.5 3.0 0.0 0.8 1.0 1.1 1.3 0.6 0.0 0.0 0.0 0.0 3.9 4.5 0.0 0.6 86.9 0.5 1.5 23.3 0.7 48.0 0.7 1.0 1.1 0.9 17.0 0.0 0.0 3.1 3.7 4.8 1.1 2.6 0.0 0.0 2.9 1.1 0.8 0.0 0.7 0.0 1.1 0.0 0.3 3.2 5.0 1.6 3.2 1.3 3.9 1.8 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460260 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 180.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 147.8;T-47d: 51.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 11.4 3.7 19.6 4.0 40.2 4.4 23.4 1.3 39.4 20.6 5.7 3.7 5.0 5.1 19.2 7.1 17.7 9.5 18.2 28.1 18.8 5.1 6.9 17.6 17.7 3.8 4.2 20.6 11.8 12.6 3.8 3.3 25.9 8.7 8.7 8.7 12.6 22.1 6.2 8.7 20.9 6.1 15.4 2.7 54.7 4.7 19.8 7.4 1.0 8.9 16.6 7.5 14.2 15.5 1.2 2.9 3.0 1.6 10.4 1.2 0.6 16.4 14.9 5.2 0.4 2.7 4.5 2.0 3.5 5.9 11.7 6.8 1.1 14.6 0.0 23.2 12.6 28.5 20.7 0.2 8.1 10.7 0.0 0.4 0.0 6.7 1.2 14.8 0.0 0.4 2.6 11.3 4.5 12.7 147.8 23.5 0.0 0.0 0.5 23.1 6.0 0.0 0.0 0.9 1.6 2.4 0.8 14.3 0.0 30.8 3.3 0.3 0.7 10.8 2.1 9.5 9.7 51.9 0.2 30.0 3.2 8.7 1.4 28.1 0.0 0.0 0.0 2.5 0.0 14.4 3.0 0.7 2.3 0.1 1.6 0.0 1.2 0.7 0.0 2.9 0.9 1.2 0.6 1.9 10.4 0.6 2.0 0.5 0.6 19.6 40.2 1.3 39.4 18.8 5.1 4.2 20.6 8.7 7.4 17.9 18.6 2.7 128.0 125.8 2.8 105.2 22.9 18.7 68.2 17.4 3.9 55.6 8.3 96.4 5.7 109.7 37.3 0.0 69.2 180.6 32.4 45.1 9.2 6.0 13.5 0.0 80.9 51.5 8.9 2.3 11.8 11.2 23.6 5.4 25.3 3.5 71.6 40.7 10.3 2.5 2.7 0.0 79.3 72.4 10.4 90.5 108.6 6.4 24.3 54.0 PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800225-44805990 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced NA NA "HPA060318: AB_2684252" "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" "unprognostic (3.69e-2)" "unprognostic (3.51e-3)" "unprognostic (3.09e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (5.12e-3)" "unprognostic (6.78e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" 14.8 7.6 4.4 16.3 18.8 8.6 10.0 2.4 6.4 8.6 5.3 13.9 3.2 4.0 9.9 5.8 23.9 8.5 21.6 6.8 10.5 6.0 6.7 9.0 14.9 10.0 9.9 2.5 7.8 10.7 15.6 9.0 29.6 14.8 6.4 4.0 7.6 8.2 6.8 7.0 16.6 7.0 6.0 15.2 9.1 6.1 4.5 5.6 4.6 8.4 25.0 18.2 9.9 9.5 1.3 4.2 2.8 5.1 0.6 11.0 3.5 4.1 2.7 4.2 1.9 3.1 10.1 7.8 9.7 13.7 3.7 3.7 1.6 5.8 5.0 4.1 7.9 12.0 3.7 2.3 13.2 2.1 8.1 0.7 5.6 1.5 3.6 15.2 1.8 7.2 7.9 8.0 11.0 10.8 12.9 11.6 1.8 2.8 2.1 8.3 2.7 3.7 1.6 2.8 2.5 3.3 4.4 2.8 7.3 13.2 1.5 3.2 2.0 2.6 4.5 10.7 6.7 0.4 1.7 14.8 2.3 5.7 4.5 5.7 5.8 2.7 1.3 4.9 2.9 4.5 0.0 2.9 0.8 1.7 5.0 2.1 1.3 9.9 4.2 4.2 1.1 11.0 4.9 2.8 0.6 5.1 1.8 10.5 3.5 4.4 18.8 2.4 6.4 10.5 6.0 9.9 2.5 14.8 5.6 11.9 41.5 19.3 51.6 39.2 5.3 2.2 12.7 9.4 12.5 5.2 2.0 13.1 0.0 17.7 0.6 29.7 73.5 0.0 11.3 19.2 25.9 18.8 78.3 5.4 35.4 6.4 50.8 24.5 18.9 0.4 9.2 52.8 11.8 10.8 21.9 5.4 18.2 66.6 4.9 2.3 9.6 25.8 26.8 1.7 4.9 29.4 49.5 24.5 28.1 55.0 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880861-127899195 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5;lymphoid tissue: 21.7;testis: 21.7" "Cell type enhanced" "Detected in many" 14 "Early spermatids: 48.9;Erythroid cells: 23.3;Late spermatids: 60.1;Spermatocytes: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.4 1.3 1.5 4.7 2.4 16.5 2.2 0.5 2.2 2.0 3.2 0.3 0.6 2.3 1.3 1.3 5.4 1.1 1.2 2.0 1.2 1.3 1.5 0.9 1.5 5.9 1.2 1.4 1.5 0.9 0.3 0.6 5.0 2.6 1.4 3.7 0.8 1.7 0.7 0.4 2.7 3.2 1.9 1.8 2.7 1.6 21.7 1.0 21.7 1.0 2.1 6.0 1.5 2.2 0.7 0.7 1.5 0.8 1.4 4.0 0.8 11.8 5.6 21.1 10.8 0.7 2.1 9.6 11.6 8.2 15.5 16.0 7.8 12.2 16.0 4.3 6.4 12.6 7.8 14.8 9.3 23.9 12.4 6.1 14.5 9.0 7.3 0.2 20.4 17.1 0.6 0.9 14.1 6.5 2.8 11.9 12.3 16.8 21.4 13.0 8.2 31.4 9.1 9.8 12.1 6.4 16.4 14.7 5.5 5.1 7.6 11.6 9.6 7.3 6.7 3.5 9.3 5.4 8.8 5.1 12.2 11.8 8.3 14.4 11.0 12.1 22.8 6.2 15.5 13.5 0.0 0.4 1.5 1.6 0.8 1.1 0.3 1.8 1.7 0.7 0.7 0.6 2.3 0.0 1.4 0.3 0.4 4.0 0.8 1.5 2.4 0.5 2.2 1.2 1.3 1.2 1.4 2.6 1.0 0.0 1.1 0.8 0.6 1.4 2.1 0.5 0.0 2.7 0.0 1.8 0.0 3.6 0.0 0.6 48.9 0.4 0.0 23.3 0.3 10.4 0.7 0.4 1.1 0.2 3.1 0.0 2.4 0.6 1.0 60.1 2.6 1.6 0.0 1.8 1.9 1.1 0.1 0.0 0.4 0.3 0.7 0.0 0.3 27.0 12.1 0.6 3.2 1.8 2.1 0.9 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Extravillous trophoblasts: 215.9;Sertoli cells: 103.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2700000 Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 29.0 19.5 14.9 16.8 24.0 7.1 32.1 12.1 17.6 35.8 21.7 17.0 17.7 19.1 34.2 21.1 16.5 24.7 21.3 31.2 17.6 14.8 27.5 51.3 22.2 19.7 24.5 9.9 31.8 30.3 18.2 16.3 41.5 20.8 21.1 12.0 25.1 39.3 22.0 18.3 13.3 20.8 39.0 13.2 21.1 18.6 10.0 22.4 1.7 34.8 11.1 8.2 19.5 69.7 1.6 16.3 17.7 19.4 2.6 9.1 9.3 16.9 14.5 8.0 37.4 54.7 30.6 6.4 50.4 67.0 26.6 45.3 16.5 11.1 9.8 53.4 55.7 19.8 14.3 11.6 17.6 18.3 10.2 12.4 5.3 23.3 20.9 33.9 3.3 25.8 37.1 9.3 32.1 12.9 90.3 47.1 2.2 14.8 4.8 27.7 11.0 0.8 8.9 3.5 17.3 21.6 3.9 16.3 21.3 15.3 3.8 3.0 12.7 22.0 15.1 25.4 13.1 7.6 8.5 46.5 30.4 22.8 38.0 24.7 11.3 18.3 5.8 67.4 11.6 49.6 0.0 19.4 0.9 9.1 17.2 1.6 1.0 1.6 4.4 16.3 1.6 0.6 3.4 17.7 2.6 15.0 2.4 1.0 9.3 14.9 24.0 12.1 17.6 17.6 14.8 24.5 9.9 20.8 22.4 0.0 9.3 3.7 7.6 6.3 4.2 16.2 10.2 4.0 5.7 10.4 2.0 34.8 3.3 30.5 1.1 20.4 18.7 0.0 8.4 215.9 28.4 9.2 0.0 29.9 41.8 6.4 8.1 46.6 21.6 1.7 41.1 15.6 10.1 18.0 9.8 10.1 24.0 12.9 23.0 13.7 2.7 103.5 26.2 0.5 3.6 4.4 28.1 4.4 11.0 3.8 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease mutation, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.1" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 109.4;Pancreatic endocrine cells: 83.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "HBF TERT88: 82.6;hTERT-RPE1: 93.9;U-87 MG: 73.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 36.7 14.1 11.2 18.0 12.1 0.7 28.5 7.9 13.5 8.8 25.2 5.1 8.3 21.6 14.8 7.5 12.0 8.0 22.3 16.6 12.5 8.2 16.4 73.1 9.3 3.0 10.7 4.8 17.7 14.4 13.9 7.8 41.0 13.0 11.1 16.1 7.2 7.7 11.3 4.8 3.2 24.7 24.2 19.4 3.2 13.6 6.3 10.9 6.1 47.6 3.5 3.0 21.8 28.7 0.0 0.0 1.5 0.3 0.0 0.0 1.9 16.4 11.8 3.7 1.2 13.5 14.5 9.4 58.5 17.9 31.9 60.2 0.9 1.7 0.0 11.4 9.9 14.6 3.5 4.3 50.3 82.6 0.0 6.8 4.1 11.5 8.2 34.7 0.0 0.0 25.4 7.2 27.6 13.5 93.9 44.0 0.0 5.4 0.2 56.3 6.0 0.0 0.0 2.3 0.0 5.1 0.0 2.4 0.0 13.4 0.8 1.8 0.0 46.6 5.0 4.9 18.1 13.6 0.5 55.2 39.5 12.0 12.5 34.9 17.9 2.5 0.0 73.6 0.0 7.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.9 11.2 12.1 7.9 13.5 12.5 8.2 10.7 4.8 13.0 10.9 14.9 10.7 0.5 5.9 6.3 14.5 10.6 61.1 12.0 13.6 26.2 33.4 6.8 8.3 62.8 0.4 21.2 46.1 0.0 45.9 109.4 34.5 8.1 0.0 50.8 4.7 0.0 19.0 18.4 1.5 1.3 12.0 2.7 13.5 1.0 18.3 65.1 83.0 31.5 4.6 6.9 22.4 19.4 38.1 8.0 16.3 4.8 15.7 0.7 21.3 5.4 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 13.4;monocytes: 14.3;T-cells: 9.2" "Cell line enhanced" "Detected in many" "Karpas-707: 105.8;WM-115: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted - unknown location" NA NA 370000 "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 23.9 16.1 11.9 19.5 24.0 14.6 35.4 7.2 19.2 17.8 20.0 31.2 16.6 22.7 22.9 15.1 11.0 17.4 16.7 22.1 14.8 11.6 20.2 54.1 21.0 18.2 36.3 8.9 16.1 23.2 18.5 16.5 33.1 22.4 14.4 14.2 11.1 11.3 19.6 8.8 14.0 23.2 23.2 29.0 20.4 16.7 10.1 30.6 5.1 16.8 6.0 6.9 17.3 42.6 2.6 13.4 2.8 14.3 2.5 9.2 5.3 10.1 9.2 3.8 25.8 18.4 13.3 7.9 18.7 21.0 19.2 13.9 14.8 13.2 0.8 21.1 32.3 14.8 12.4 7.7 11.0 4.9 5.5 3.5 1.0 11.1 14.4 25.4 4.6 8.7 14.3 10.5 11.2 8.9 18.2 17.0 0.7 9.8 105.8 12.9 29.0 0.4 10.9 8.1 17.5 14.0 3.2 5.2 15.7 6.5 3.0 2.9 17.5 11.6 17.0 41.7 10.7 3.2 15.9 14.8 29.1 14.2 35.2 22.9 5.9 10.8 0.6 17.2 11.1 102.0 0.0 10.8 2.8 9.2 14.3 8.1 2.6 6.8 6.1 10.4 1.8 3.2 3.4 1.0 2.5 14.3 13.4 4.3 5.3 11.9 24.0 7.2 19.2 14.8 11.6 36.3 8.9 22.4 30.6 20.8 8.3 9.0 8.8 7.9 5.1 12.3 17.8 12.0 7.9 24.4 13.7 16.7 1.7 35.7 0.4 23.6 35.9 0.0 27.6 62.3 31.0 7.5 19.6 16.6 45.4 7.9 15.5 27.0 21.6 1.5 24.2 16.4 59.1 20.8 16.2 10.8 29.4 28.1 13.8 10.5 5.9 19.4 17.6 7.2 12.6 4.3 15.8 8.6 21.1 4.2 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669730-153689010 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;seminal vesicle: 38.5" "Cell type enhanced" "Detected in some" 13 "Bipolar cells: 16.5;Cone photoreceptor cells: 21.6;Extravillous trophoblasts: 44.0;Rod photoreceptor cells: 19.4;Syncytiotrophoblasts: 41.4" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AN3-CA: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.8 21.4 2.2 35.4 0.6 0.9 3.7 24.9 0.9 21.9 0.9 6.9 3.8 4.2 3.1 14.5 2.9 2.9 3.8 19.5 17.0 1.0 0.5 0.7 0.6 6.1 15.5 0.7 0.5 1.4 0.3 2.4 3.8 12.6 4.2 0.4 0.7 38.5 2.2 1.4 5.2 15.3 2.6 0.7 5.5 4.7 1.7 0.0 0.5 0.0 0.7 10.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.4 27.1 0.0 0.0 2.9 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.3 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.3 0.2 0.1 0.5 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.2 0.0 0.1 2.2 0.8 0.3 0.3 0.0 0.2 1.1 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.4 3.7 23.2 19.5 17.0 6.1 15.5 3.8 1.7 0.0 0.0 0.0 0.4 0.6 16.5 2.8 0.0 0.0 0.0 0.0 21.6 8.3 0.0 0.2 0.2 0.3 2.0 0.0 0.3 44.0 0.2 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.4 2.7 4.8 0.0 0.4 0.1 19.4 0.0 0.4 0.5 0.6 0.5 41.4 0.0 0.0 0.9 PNKP PNK ENSG00000039650 "Polynucleotide kinase 3'-phosphatase" Q96T60 19 49859882-49878351 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease mutation, Epilepsy, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006782 Supported Supported Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA006782: AB_1855496" "prognostic favorable (9.18e-4)" "unprognostic (1.87e-1)" "unprognostic (4.31e-2)" "unprognostic (4.23e-1)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (4.55e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.24e-2)" "unprognostic (3.68e-3)" 13.1 32.4 11.2 22.0 11.8 24.3 15.0 18.0 13.8 14.0 17.4 17.0 26.4 15.6 16.7 25.3 13.6 18.1 18.2 16.8 12.3 9.5 20.1 16.8 15.9 21.0 13.9 14.2 17.1 22.5 19.7 26.8 17.1 12.9 18.7 15.0 19.6 20.3 22.4 12.8 15.3 15.7 13.2 10.1 30.7 17.9 17.2 13.9 22.3 23.0 17.0 20.6 14.6 12.4 7.9 7.5 19.3 12.7 2.7 7.7 3.8 13.0 8.8 8.9 14.0 8.5 6.6 14.5 21.1 10.8 9.8 8.6 7.0 17.2 8.5 6.7 6.4 5.7 10.7 3.2 11.9 5.8 10.9 13.5 14.4 16.6 6.1 6.4 13.6 19.3 6.2 6.3 8.9 5.8 8.7 12.8 10.7 7.0 17.1 12.7 8.3 13.7 10.8 8.3 13.5 18.0 11.7 8.2 17.1 10.0 27.9 10.6 17.1 9.2 27.8 4.7 8.1 4.8 8.4 18.1 19.1 11.7 4.6 17.4 18.9 7.6 6.9 17.3 6.1 15.2 1.4 8.8 12.2 7.7 8.5 6.4 6.5 6.6 5.8 7.5 7.9 4.9 4.4 19.3 2.7 12.7 4.3 6.8 3.8 11.2 11.8 18.0 13.8 12.3 9.5 13.9 14.2 12.9 13.9 14.9 23.4 40.2 28.5 11.8 40.7 8.9 15.3 24.1 9.1 19.2 76.6 37.9 19.9 36.3 12.0 20.2 24.9 0.0 34.6 29.2 14.8 28.4 27.8 18.7 34.1 31.8 29.3 31.9 22.4 20.0 55.0 24.9 13.5 42.3 23.1 20.6 38.1 20.1 42.1 26.9 76.0 19.4 14.4 18.2 29.6 11.4 41.2 42.4 27.4 25.2 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.4" "Cell type enhanced" "Detected in many" 9 "Hepatocytes: 443.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 12.8 48.2 7.4 7.5 10.8 3.6 15.0 5.3 16.4 11.0 20.8 9.6 32.1 24.9 9.0 8.2 13.4 12.8 9.9 8.4 7.1 7.2 12.0 78.4 13.7 9.9 5.2 10.1 14.4 12.8 12.1 18.5 18.6 7.1 9.3 5.3 10.8 7.8 58.7 13.1 10.0 24.3 7.0 5.2 11.7 9.8 22.4 5.0 8.2 33.3 9.9 8.6 9.8 10.2 5.7 20.6 26.7 18.4 11.2 9.9 13.9 12.8 28.2 12.9 24.0 48.9 18.6 21.6 5.4 17.7 10.2 14.3 21.1 57.3 12.3 5.0 11.7 34.8 6.3 16.9 8.5 4.4 10.5 12.5 5.7 8.3 39.0 34.0 5.7 10.2 38.1 10.7 13.4 9.8 8.2 9.4 6.1 17.0 5.3 9.1 18.9 6.1 10.2 16.1 20.2 16.0 8.8 8.5 13.2 11.5 15.6 13.5 12.9 14.5 74.1 19.5 7.6 21.2 9.6 8.5 9.6 10.6 14.4 10.6 5.2 8.0 8.4 13.6 8.7 12.3 26.7 18.4 25.3 9.9 17.7 8.3 5.4 8.4 9.2 20.6 5.7 8.4 7.1 24.3 11.2 13.0 5.8 8.7 13.9 7.4 10.8 5.3 16.4 7.1 7.2 5.2 10.1 7.1 5.0 35.7 31.2 12.6 24.7 15.1 30.1 9.3 56.0 78.9 37.5 69.8 11.8 88.1 1.7 55.5 13.2 25.3 144.8 0.0 25.7 71.6 24.8 20.8 24.3 443.8 58.9 14.3 19.0 27.6 38.6 6.1 70.2 40.5 11.8 16.2 29.0 33.2 24.3 119.3 105.7 27.5 21.8 64.7 30.9 14.7 32.6 12.8 161.6 20.0 36.8 40.7 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Erythroid cells: 93.5;Hepatocytes: 134.7;Rod photoreceptor cells: 152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 12.1;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 5 "dendritic cells: 3.8;granulocytes: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 5.7 6.6 5.8 6.0 6.2 4.2 6.9 2.6 4.5 3.8 11.8 5.9 9.9 13.9 4.8 6.6 6.3 3.9 9.1 19.6 5.1 4.1 17.8 30.9 3.8 3.4 6.1 4.9 9.1 13.4 6.6 3.5 3.1 7.8 6.2 7.1 13.5 8.1 8.2 17.1 5.8 19.7 5.0 4.7 3.5 5.7 2.7 7.1 1.3 5.4 10.4 4.8 7.3 12.3 1.5 3.8 12.1 1.4 0.9 1.5 0.3 6.9 1.7 2.2 7.7 12.4 8.0 4.9 6.1 12.1 6.6 6.8 3.4 3.4 2.5 3.1 14.1 6.0 3.1 6.5 8.0 5.9 7.2 8.3 7.7 4.4 7.1 7.7 5.3 13.3 6.3 6.4 4.8 11.1 5.6 1.4 5.7 2.8 5.8 6.1 1.8 6.0 1.9 0.3 5.8 1.7 7.1 8.0 3.2 4.5 4.1 2.2 6.6 2.3 2.2 7.7 3.2 2.5 4.1 2.3 6.8 7.4 6.2 2.6 5.9 3.4 1.0 10.7 6.0 2.1 1.7 1.0 12.1 1.4 1.4 1.2 1.0 0.7 0.7 0.7 1.5 0.8 0.6 0.8 0.9 0.8 3.8 1.5 0.3 5.8 6.2 2.6 4.5 5.1 4.1 6.1 4.9 7.8 7.1 3.0 9.9 5.2 13.1 20.7 14.7 84.0 25.5 2.7 7.9 7.0 58.9 6.8 8.3 7.2 0.4 16.1 66.1 93.5 14.3 5.4 13.0 13.9 4.7 134.7 7.4 4.8 19.1 20.9 22.5 0.4 18.1 9.6 3.3 11.8 34.6 15.2 11.6 24.6 28.3 36.9 152.6 6.5 14.4 0.7 1.7 29.9 2.5 7.5 31.6 17.9 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;testis: 20.2" "Group enriched" "Detected in some" 11 "Early spermatids: 51.1;Late spermatids: 94.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 3.6;HAP1: 1.3;HeLa: 5.3;SH-SY5Y: 2.9;SK-MEL-30: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.5 3.1 0.2 6.4 1.4 3.9 0.2 10.6 0.2 0.2 0.1 0.0 0.1 0.3 0.9 0.2 0.2 0.3 0.3 1.9 1.0 0.3 0.1 0.4 0.3 1.7 6.9 0.2 0.2 0.1 0.7 1.0 0.2 0.5 0.1 0.0 0.3 0.6 0.1 0.7 0.1 0.2 10.5 0.3 0.1 20.2 0.0 0.1 0.4 0.0 0.3 0.4 0.1 0.2 1.3 0.0 0.9 0.0 0.0 0.2 0.0 3.6 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 1.2 0.0 5.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.1 6.4 0.2 10.6 1.9 1.0 1.7 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 51.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.4 0.0 0.0 0.0 94.3 0.6 0.0 3.3 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 PPEF2 PPP7CB ENSG00000156194 "Protein phosphatase with EF-hand domain 2" O14830 4 75859864-75902571 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "retina: 75.7" "Group enriched" "Detected in some" 22 "Cone photoreceptor cells: 157.1;Rod photoreceptor cells: 518.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (3.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (1.53e-1)" "unprognostic (9.02e-2)" "unprognostic (3.32e-4)" "unprognostic (2.74e-2)" "unprognostic (4.54e-8)" "unprognostic (2.89e-1)" "unprognostic (5.98e-2)" "unprognostic (5.16e-1)" "unprognostic (3.66e-3)" 0.1 0.0 0.0 0.2 0.4 0.2 0.3 3.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 75.7 0.0 0.0 0.3 0.4 0.1 0.1 0.1 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 3.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.3 0.0 0.0 0.0 0.0 157.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.2 518.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" NA NA 420000000 "CAB004655: AB_425607, HPA058345: AB_2683685" "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" 92.0 90.3 147.0 80.4 124.3 105.9 169.0 88.9 148.0 111.3 143.5 81.6 52.9 73.9 74.8 125.1 176.5 76.3 80.4 60.2 132.0 121.9 149.2 214.3 95.4 137.1 123.2 88.3 74.2 103.2 93.1 58.3 96.2 142.5 83.0 149.1 68.1 84.7 102.3 68.4 114.7 105.1 113.9 120.8 137.0 73.1 62.4 59.8 228.2 130.2 123.4 191.2 94.3 93.1 129.8 158.5 35.0 83.1 76.0 117.7 180.3 85.4 114.8 145.8 105.8 122.2 185.9 48.1 125.3 196.9 240.8 236.3 127.3 131.1 193.3 64.6 159.6 265.6 116.9 187.4 240.0 222.2 110.5 136.7 78.1 132.3 121.2 99.2 158.2 81.5 136.0 164.8 170.6 187.5 123.7 244.4 134.0 160.4 156.3 247.6 121.7 173.3 280.1 166.4 289.1 158.3 124.5 88.3 245.9 326.5 120.9 109.2 90.5 105.6 303.0 82.3 181.0 162.4 216.0 108.6 124.1 119.7 83.0 164.2 114.1 225.3 326.2 108.2 180.1 187.2 23.4 74.5 35.0 94.9 83.1 102.0 129.8 97.0 97.1 134.8 103.9 80.3 88.2 9.2 76.0 77.7 158.5 117.7 180.3 147.0 124.3 88.9 148.0 132.0 121.9 123.2 88.3 142.5 59.8 738.4 649.6 630.7 788.0 769.8 81.7 43.6 573.3 655.8 728.0 572.3 17.7 772.4 1198.7 1053.9 61.2 614.7 668.4 210.2 1054.9 1359.4 612.8 450.0 590.8 641.5 1374.9 104.9 508.7 685.7 1073.8 53.8 539.0 844.5 656.3 1506.8 976.8 169.9 1130.2 533.1 576.3 1183.4 66.5 388.1 545.9 364.4 288.3 865.6 509.5 657.9 1124.8 784.3 PPIAL4A "COAS2, PPIAL4, PPIAL4B" ENSG00000263353 "Peptidylprolyl isomerase A like 4A" Q9Y536 1 120889746-120890405 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 3.5;intestine: 1.6" "Cell type enriched" "Detected in single" 10 "Distal tubular cells: 1.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 3.8;NB-4: 4.6;SK-BR-3: 4.7" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (3.49e-3)" "unprognostic (2.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-2)" "unprognostic (1.74e-1)" 0.3 0.8 1.0 1.4 0.2 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 3.0 3.2 0.6 1.6 2.2 2.4 3.5 0.9 0.0 0.1 1.4 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 1.0 0.7 0.2 0.0 0.3 1.8 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.2 3.8 0.3 0.6 1.7 4.6 2.5 0.0 0.0 0.8 1.5 1.9 0.0 0.0 1.0 0.3 0.3 4.7 0.4 0.1 3.1 2.5 0.7 3.0 1.2 2.9 1.7 1.4 0.9 2.5 2.6 1.6 3.2 0.2 1.6 0.6 1.4 1.2 1.4 3.0 2.3 2.4 3.1 2.2 1.5 2.4 0.0 2.2 1.2 3.2 2.4 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4C ENSG00000263464 "Peptidylprolyl isomerase A like 4C" A0A0B4J2A2 1 149583865-149584464 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 10.9;intestine: 5.5" "Cell type enriched" "Detected in single" 16 "Cardiomyocytes: 1.6" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 14.4;THP-1: 16.9" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (3.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (6.61e-2)" "unprognostic (2.25e-1)" 0.0 3.3 2.7 0.1 0.0 1.5 0.0 0.8 5.5 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 2.9 0.2 0.0 0.9 0.7 0.3 0.0 0.0 0.0 0.2 0.5 2.9 0.0 1.4 0.9 0.0 0.0 0.3 0.0 9.1 9.7 1.9 6.0 4.6 7.8 10.9 3.6 0.3 0.4 3.1 0.1 0.3 2.0 0.6 0.4 1.0 0.7 0.0 4.8 1.3 2.1 0.0 2.5 3.9 0.0 0.2 0.6 3.5 0.0 0.5 0.0 0.0 0.1 2.0 1.9 0.1 0.5 0.6 0.3 0.0 0.0 0.5 0.9 5.4 0.7 0.4 5.3 14.4 6.2 1.0 0.1 5.3 0.0 9.0 0.2 0.0 4.0 5.5 1.1 11.3 6.2 0.3 5.3 16.9 1.3 3.6 5.6 3.3 8.2 4.2 5.6 9.2 3.9 4.6 7.8 0.9 4.3 1.9 5.4 6.0 6.0 9.1 6.1 5.7 9.4 7.2 5.0 5.9 0.0 4.6 5.3 9.7 7.8 10.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4E ENSG00000271567 "Peptidylprolyl isomerase A like 4E" A0A075B759 1 144372875-144373659 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "blood: 3.4;bone marrow: 2.7;skeletal muscle: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;HL-60: 1.2;hTERT-RPE1: 1.9;NB-4: 1.4;SK-BR-3: 2.0;TIME: 1.9" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (6.97e-2)" "unprognostic (5.22e-2)" "unprognostic (2.28e-1)" 0.0 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 1.9 2.0 3.4 2.9 0.6 0.6 0.5 0.4 0.1 0.0 0.0 0.4 0.2 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.3 1.0 0.0 0.0 1.9 0.1 0.5 0.3 0.0 0.6 0.4 0.2 0.0 0.2 0.0 0.0 2.0 1.0 2.9 0.5 1.9 1.3 1.6 1.3 0.5 1.7 0.5 0.5 1.9 3.4 1.5 0.6 0.8 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPIAL4G ENSG00000236334 "Peptidylprolyl isomerase A like 4G" P0DN37 1 148479824-148483679 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "brain: 6.9;skeletal muscle: 6.8" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 6.1;Suprabasal keratinocytes: 10.9;T-cells: 6.7" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA058345 Uncertain NA NA "HPA058345: AB_2683685" "unprognostic (2.17e-3)" "unprognostic (3.63e-1)" "unprognostic (4.83e-1)" "unprognostic (2.26e-1)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (3.95e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" 0.2 0.1 1.3 0.7 1.8 1.3 0.3 6.9 1.2 0.1 0.2 0.5 0.4 1.0 0.3 0.1 0.3 0.2 0.9 1.1 0.1 0.2 0.2 1.1 0.5 0.4 0.0 0.1 0.3 0.1 0.2 0.3 0.4 0.0 6.8 0.8 0.7 0.0 0.4 2.7 0.5 0.5 0.4 0.3 0.0 0.0 2.2 0.6 2.4 0.8 2.4 3.2 0.2 0.8 1.1 0.5 1.7 0.2 0.3 1.3 0.3 0.3 0.1 0.1 1.3 0.9 1.2 0.8 0.3 0.2 1.0 0.1 0.2 0.2 0.5 0.7 1.2 2.4 1.0 0.1 1.5 1.2 0.2 1.8 0.1 0.3 0.3 0.2 1.0 0.7 1.8 0.0 0.9 0.8 2.5 1.1 0.1 0.3 0.6 0.3 0.8 0.3 1.3 0.7 1.0 1.0 0.7 0.4 0.9 1.2 1.4 0.8 0.9 0.9 1.4 0.7 1.4 1.2 1.0 0.7 1.0 0.9 2.2 0.4 1.0 3.2 0.4 2.4 0.9 1.5 1.7 0.3 2.2 1.6 2.8 2.4 2.4 0.8 0.6 0.5 0.2 0.0 1.1 0.0 0.4 6.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 1.1 0.4 0.2 1.6 0.0 0.6 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 10.9 0.1 6.7 0.0 0.1 PPIB "CYPB, OI9" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155812-64163205 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Isomerase, Rotamase" "Disease mutation, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" No No 120000000 "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 56.9 64.3 23.9 49.3 26.9 54.9 48.1 15.1 32.1 75.3 44.1 35.4 102.8 42.0 64.2 106.9 48.0 54.8 58.1 44.5 23.8 27.3 89.5 285.9 57.2 63.8 29.7 19.6 67.5 193.7 26.7 71.8 120.2 27.5 51.0 47.7 36.2 123.3 95.4 19.5 33.1 57.5 54.3 30.7 78.0 47.7 27.2 29.5 53.7 154.3 45.7 69.1 49.2 51.7 63.5 191.6 41.0 51.1 44.9 71.6 87.1 39.7 50.0 45.2 102.6 158.3 91.9 39.8 94.9 124.7 75.2 89.4 71.9 73.8 38.0 77.2 147.0 76.4 64.9 82.5 63.8 38.8 24.1 31.1 53.6 55.2 94.1 166.0 53.4 48.5 84.6 68.8 43.8 106.9 93.2 90.8 18.2 37.3 132.4 56.9 63.5 16.3 82.0 39.4 110.7 32.2 31.2 48.0 193.7 78.0 62.0 25.6 40.3 43.5 74.8 69.1 69.6 44.7 163.5 55.8 75.2 62.3 42.0 64.0 71.9 69.6 39.9 70.2 86.1 75.0 41.0 51.1 33.9 71.6 39.2 71.5 63.5 50.5 58.1 67.4 38.0 33.0 44.2 25.5 44.9 25.2 191.6 40.1 87.1 23.9 26.9 15.1 32.1 23.8 27.3 29.7 19.6 27.5 29.5 116.1 168.3 153.4 361.8 142.3 26.7 0.7 280.2 128.5 194.5 258.2 29.5 546.5 76.3 534.3 16.2 209.5 301.3 70.0 495.6 1107.3 581.4 486.2 176.7 431.7 566.9 42.9 284.9 371.4 213.7 20.8 422.5 284.2 266.6 285.9 313.7 126.6 471.5 326.7 369.5 231.9 33.9 226.4 234.9 37.1 72.8 126.6 935.7 261.7 353.5 357.9 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036741 "Enzymes, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Fibroblasts: 273.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 58.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 5700000 "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 22.5 13.7 3.3 10.8 3.6 0.0 29.9 1.6 4.2 24.3 30.0 3.6 26.6 15.7 20.4 32.7 35.5 9.0 25.8 43.7 4.0 2.7 27.4 24.0 16.3 9.0 3.7 2.1 13.3 24.3 8.7 5.8 28.3 10.0 17.8 22.0 5.3 25.9 18.0 18.4 12.0 35.2 37.9 5.4 8.9 13.5 8.0 3.2 2.5 42.7 29.6 12.9 31.5 21.5 0.0 1.1 0.0 0.1 0.0 0.3 0.0 4.7 4.1 1.6 33.9 58.9 27.1 6.7 13.4 10.5 7.0 14.4 6.8 31.8 0.0 23.8 35.9 21.0 5.3 4.6 16.8 5.6 0.0 8.2 6.7 15.4 7.8 15.1 0.0 3.7 16.9 12.9 8.1 8.6 12.6 14.4 0.0 1.8 0.0 5.0 27.9 0.0 0.0 2.9 29.2 7.2 0.0 3.6 0.0 22.0 16.3 2.1 3.7 26.2 12.7 2.8 20.5 17.9 15.0 15.9 13.4 8.4 4.6 5.7 0.0 0.0 0.0 11.6 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 3.3 3.6 1.6 4.2 4.0 2.7 3.7 2.1 10.0 3.2 29.8 13.9 0.9 43.9 42.1 13.9 38.9 53.5 25.4 14.8 69.8 3.9 50.1 24.9 171.5 1.0 100.3 130.1 0.0 111.8 45.8 273.0 38.3 1.1 48.9 36.5 0.0 12.2 66.9 4.8 3.5 104.2 7.7 30.4 5.4 148.2 1.8 98.5 178.9 94.0 64.2 3.8 38.8 61.4 26.6 14.1 43.2 20.9 2.2 72.5 66.5 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709134-158723396 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 16.8 25.8 20.1 15.5 21.4 14.9 22.3 26.7 26.8 12.6 16.8 14.4 18.2 33.4 14.6 13.6 16.5 15.4 13.0 28.8 19.4 22.1 21.5 45.3 11.0 17.4 22.6 18.9 14.6 17.5 11.3 30.3 14.5 26.0 16.1 14.2 9.1 15.4 13.7 53.3 24.0 29.2 13.1 22.7 16.5 15.5 16.9 23.4 22.7 21.7 16.0 16.8 15.4 55.0 15.6 17.2 33.4 22.2 23.9 24.4 17.1 15.5 14.5 14.6 20.0 21.7 16.3 22.1 15.4 8.4 14.2 10.8 18.8 10.7 16.5 6.9 14.3 22.3 12.0 44.2 17.7 17.3 54.5 15.4 29.5 13.1 25.8 16.8 18.4 22.2 10.3 14.4 12.1 18.2 18.4 15.4 28.2 36.7 29.4 15.8 14.9 26.4 16.7 20.1 25.5 19.4 12.0 7.2 14.1 15.6 7.8 24.7 16.6 11.5 24.0 21.9 22.1 11.0 17.7 14.9 14.2 16.0 15.6 20.3 16.9 35.0 21.0 18.1 20.0 14.2 33.4 15.3 33.2 21.2 22.2 24.4 14.6 20.7 19.6 16.7 15.6 21.5 22.0 20.9 23.9 22.0 17.2 22.4 17.1 20.1 21.4 26.7 26.8 19.4 22.1 22.6 18.9 26.0 23.4 6.0 12.0 18.8 25.3 9.0 24.6 50.0 28.1 76.3 33.0 26.2 21.6 33.4 31.5 34.8 23.6 25.6 19.0 0.0 20.1 39.2 21.3 25.8 31.2 16.1 36.7 71.5 18.8 18.4 11.0 15.7 19.0 21.8 13.5 63.1 22.9 21.7 26.7 21.6 21.2 24.9 25.3 6.5 30.2 78.8 76.3 10.3 39.8 27.4 24.2 17.2 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 19.3 23.8 23.7 24.3 22.5 18.6 25.7 25.9 36.1 25.5 28.1 35.6 22.2 19.7 30.6 26.5 26.0 34.7 21.1 27.1 22.3 22.1 25.2 29.8 20.6 25.9 26.3 20.5 35.5 42.1 27.4 23.6 21.9 24.9 26.1 22.7 26.9 30.7 28.9 29.6 21.7 23.2 34.2 25.6 25.7 23.9 38.8 20.2 22.8 33.7 21.9 33.9 31.5 22.6 43.3 31.6 14.1 27.2 49.0 46.9 44.2 9.8 17.1 15.7 12.6 17.5 15.6 8.3 17.0 17.1 26.0 24.5 21.3 29.2 28.0 24.1 19.0 16.7 15.1 21.5 25.2 24.8 18.1 23.2 30.9 19.8 6.4 24.0 27.8 16.9 14.1 23.1 24.4 9.0 18.9 23.3 25.0 31.3 19.6 18.9 17.7 12.8 22.6 18.8 23.3 19.1 19.0 11.8 15.9 19.6 18.4 22.4 17.9 17.8 14.5 12.3 19.4 18.2 73.1 15.1 16.3 18.1 20.2 26.0 26.9 26.9 19.4 11.3 35.9 25.6 11.6 27.1 14.1 38.3 27.0 37.0 43.3 39.7 38.2 31.6 39.8 46.9 38.9 2.2 49.0 27.2 28.5 40.0 44.2 23.7 22.5 25.9 36.1 22.3 22.1 26.3 20.5 24.9 20.2 29.8 27.1 41.2 35.7 22.0 24.9 29.6 17.8 64.3 56.9 31.4 13.7 54.2 56.3 49.6 25.8 24.5 23.9 0.0 42.1 51.6 34.0 28.9 54.3 27.6 48.7 22.3 27.6 25.8 36.1 47.7 27.6 34.0 37.1 53.3 28.0 35.4 38.6 28.1 42.5 54.9 25.9 58.2 41.0 62.7 44.8 23.1 29.1 40.6 33.0 29.5 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 32.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 27000000 Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 16.5 76.2 12.1 15.7 18.8 52.0 16.9 7.1 21.3 8.3 18.1 27.1 13.2 13.3 5.2 7.6 21.0 8.8 10.0 36.5 13.0 14.5 21.0 73.1 9.4 19.4 23.3 16.6 7.2 42.0 12.0 6.2 11.3 25.2 6.6 19.9 7.5 12.7 21.9 44.4 22.5 11.1 9.9 28.0 19.6 34.0 20.8 18.0 8.8 10.0 73.9 19.8 12.5 11.0 8.0 18.6 32.8 14.9 3.6 5.0 6.5 35.6 15.2 10.7 21.0 10.0 13.0 13.7 20.8 27.3 45.8 43.4 35.5 17.3 37.1 11.6 14.6 32.6 21.4 33.1 19.4 71.5 11.7 31.2 58.1 14.9 62.4 17.0 40.0 13.8 30.4 13.9 45.4 45.5 14.9 8.0 14.6 56.5 45.8 15.5 18.3 10.3 33.5 9.0 16.4 84.5 17.8 16.5 19.0 17.8 33.3 21.3 15.8 10.7 43.3 16.0 7.3 18.9 30.9 7.2 20.1 18.3 23.6 40.0 21.3 21.6 30.0 19.9 52.1 5.4 5.1 14.9 7.3 4.7 11.4 5.0 8.0 4.2 4.3 18.6 3.9 3.8 3.7 32.8 3.6 4.1 2.3 4.2 6.5 12.1 18.8 7.1 21.3 13.0 14.5 23.3 16.6 25.2 18.0 6.0 5.0 34.4 26.4 37.8 4.4 106.2 15.3 12.0 9.1 12.2 5.9 70.1 77.9 37.7 11.0 13.8 22.2 46.7 24.2 113.4 24.0 17.4 13.8 70.1 83.0 7.9 20.7 8.6 32.4 11.1 5.8 60.2 33.7 33.3 62.3 9.9 40.0 17.5 5.6 31.1 4.9 19.4 24.1 7.0 22.2 33.0 119.0 17.5 63.7 28.5 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584340-169641406 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.2 25.3 28.5 23.8 45.3 39.2 26.7 45.0 40.7 33.1 27.1 14.6 26.0 25.3 27.1 28.1 29.4 24.3 21.2 24.2 30.0 20.3 26.0 41.1 25.5 30.4 27.7 35.9 29.5 22.8 39.4 56.7 26.0 38.0 29.3 23.9 13.8 28.6 28.8 27.8 24.5 30.8 31.9 39.7 29.7 24.1 19.8 33.7 24.1 28.4 22.6 29.9 37.4 27.6 36.4 23.7 41.7 24.7 18.7 29.6 13.3 19.5 9.3 26.3 14.4 14.6 17.9 24.8 22.4 16.8 16.5 17.1 25.4 22.6 33.7 20.6 16.1 20.7 18.8 20.6 18.3 24.5 23.4 16.6 50.7 13.9 30.9 14.1 47.7 22.6 15.0 20.7 22.4 25.2 15.7 18.1 20.6 48.9 28.2 18.8 15.8 35.2 29.3 37.7 15.9 9.5 32.4 26.3 32.9 20.4 29.4 23.0 15.2 24.0 17.9 24.3 21.1 16.7 27.6 20.8 21.6 16.5 14.4 18.3 16.4 23.6 47.1 15.9 25.6 19.7 20.7 20.0 29.9 20.3 20.1 23.2 27.6 27.0 23.8 14.9 36.4 29.6 23.7 41.7 18.7 24.7 23.7 22.9 13.3 28.5 45.3 45.0 40.7 30.0 20.3 27.7 35.9 38.0 33.7 205.4 160.5 152.0 169.4 134.5 178.8 130.1 61.1 132.5 155.8 89.0 51.1 146.0 68.0 90.9 6.8 121.2 97.1 70.0 90.5 147.9 117.4 133.0 172.3 157.2 134.3 208.2 100.6 106.2 118.2 8.4 131.5 135.1 104.6 124.4 115.6 123.1 82.2 108.7 137.9 99.6 103.2 161.7 154.6 225.0 148.0 150.9 171.9 152.4 132.6 136.1 PPIH "CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP" ENSG00000171960 "Peptidylprolyl isomerase H" O43447 1 42658425-42676758 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059019 Approved NA NA "HPA059019: AB_2683885" "unprognostic (7.93e-3)" "unprognostic (5.49e-3)" "unprognostic (2.53e-2)" "unprognostic (6.42e-2)" "unprognostic (3.79e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (2.84e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.78e-9)" "unprognostic (6.59e-3)" "unprognostic (4.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" 17.5 19.7 20.4 35.7 19.6 40.7 21.4 23.9 23.3 19.5 24.0 20.9 14.7 18.0 29.8 24.2 29.6 19.2 14.4 21.2 18.0 16.1 17.5 13.6 17.8 31.0 15.8 19.9 22.0 17.7 7.0 15.2 24.6 17.2 17.1 26.5 19.2 24.4 18.8 18.4 20.9 20.7 20.8 15.0 27.2 18.0 21.1 18.6 39.7 26.9 28.1 36.8 15.3 20.3 20.0 14.9 16.8 12.3 18.5 26.3 14.0 19.3 12.5 15.8 22.1 5.2 9.9 21.3 13.2 9.3 24.7 22.6 19.7 22.1 32.0 16.6 9.7 12.0 15.7 28.7 20.2 26.0 26.9 23.2 30.4 23.0 18.2 4.5 58.2 17.8 6.4 10.7 23.0 18.0 9.6 11.5 31.0 37.6 18.2 12.1 16.2 45.1 82.0 38.8 18.6 15.0 25.3 29.4 28.4 11.8 12.6 12.4 22.5 11.6 19.3 14.5 20.5 10.6 85.3 9.5 10.9 27.9 14.9 31.5 11.8 27.5 58.2 12.2 54.5 17.8 12.6 8.8 16.8 21.0 12.3 19.8 20.0 21.7 23.9 11.7 19.2 22.3 26.3 1.8 18.5 11.2 14.9 20.2 14.0 20.4 19.6 23.9 23.3 18.0 16.1 15.8 19.9 17.2 18.6 17.9 20.2 42.4 37.9 25.6 8.9 12.2 15.3 16.0 14.8 21.0 3.9 53.8 38.1 23.6 19.6 18.3 12.3 0.0 23.0 87.1 17.1 22.2 30.1 9.6 45.9 4.8 20.6 18.4 15.3 7.6 27.0 26.9 15.1 27.9 25.8 14.3 22.0 17.5 20.1 25.0 11.8 19.4 16.9 16.3 29.6 18.7 31.7 41.5 31.9 30.1 PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36875024 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Extravillous trophoblasts: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA Nucleoli "HPA062916: AB_2684904" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-3)" "unprognostic (1.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (2.01e-1)" "unprognostic (3.37e-2)" "prognostic favorable (4.90e-4)" "unprognostic (6.58e-2)" "unprognostic (5.49e-2)" "unprognostic (8.99e-2)" "unprognostic (1.30e-1)" "unprognostic (2.30e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-2)" 9.0 17.2 15.9 11.1 23.1 7.3 12.3 16.6 18.7 11.1 10.2 13.0 5.7 8.7 13.7 11.7 13.1 17.5 7.5 29.7 13.2 19.8 17.6 34.3 7.5 13.4 15.0 15.5 13.2 36.7 10.6 19.4 16.0 15.3 11.2 13.2 11.0 12.0 12.5 11.7 5.6 8.2 17.4 15.8 10.3 8.5 14.0 11.0 10.2 23.5 13.4 17.4 12.2 8.1 7.7 6.6 1.1 4.4 5.0 15.0 6.9 14.3 11.3 29.9 19.9 4.0 8.5 16.2 14.5 9.7 22.0 18.3 19.8 9.5 22.0 18.4 10.2 29.0 11.6 35.3 24.2 25.2 18.3 29.5 26.0 7.4 26.1 13.4 22.2 10.9 6.3 11.5 16.9 31.6 8.1 19.6 21.3 48.8 10.7 15.8 13.6 26.4 10.2 19.8 27.5 15.3 21.3 26.2 19.7 13.0 10.1 31.8 16.8 9.7 10.4 19.1 23.0 15.2 18.9 11.9 17.0 15.7 12.9 24.2 11.8 30.6 40.1 5.4 41.2 32.3 1.1 3.2 0.8 11.2 4.4 15.0 7.7 9.3 10.7 6.6 6.2 10.5 12.3 0.9 5.0 2.1 5.6 6.8 6.9 15.9 23.1 16.6 18.7 13.2 19.8 15.0 15.5 15.3 11.0 6.0 6.9 6.7 16.2 2.7 14.1 40.3 7.6 20.1 7.9 5.2 3.9 50.9 19.9 22.9 21.9 9.2 2.6 0.0 17.8 54.4 8.4 9.5 10.4 6.8 25.9 15.9 3.5 3.7 2.8 8.5 6.4 9.5 6.8 11.8 8.5 25.1 18.1 7.0 11.7 10.2 10.5 6.5 8.9 14.4 49.0 4.0 21.2 7.5 10.3 8.6 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666009-21700015 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 71.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "HPA035344: AB_10672863, HPA055637: AB_2682869" "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 15.0 21.5 19.4 20.9 24.6 16.6 13.5 24.1 30.9 17.7 17.4 25.3 19.1 18.6 21.8 17.0 22.3 15.7 16.5 20.0 17.2 17.1 21.2 20.3 14.6 23.7 15.6 20.9 16.6 31.4 23.6 30.2 31.4 19.0 19.5 17.6 23.6 22.0 16.5 25.5 17.5 19.1 15.2 15.0 21.3 19.5 18.4 17.6 32.8 27.0 13.6 33.5 17.4 16.2 8.7 11.7 4.8 17.3 12.8 13.2 9.1 6.6 6.9 8.1 8.5 8.3 7.1 7.3 8.7 6.2 10.7 9.2 7.0 4.4 11.5 5.3 9.7 5.4 9.8 10.8 7.5 6.4 7.1 11.1 10.7 6.9 8.3 6.0 16.9 10.1 7.7 6.8 7.6 5.8 6.5 9.2 7.3 71.2 8.3 7.6 10.4 7.6 4.6 7.8 12.4 4.3 9.8 12.0 2.3 5.4 6.7 12.7 6.9 7.9 12.7 2.9 5.0 9.1 5.7 11.1 6.7 11.0 7.9 5.5 9.6 7.0 8.7 7.6 6.4 8.1 1.0 8.6 4.7 9.5 13.9 11.4 7.0 11.1 12.0 11.7 8.7 9.8 8.9 4.8 12.8 17.3 11.1 13.2 9.1 19.4 24.6 24.1 30.9 17.2 17.1 15.6 20.9 19.0 17.6 8.9 25.6 20.6 7.3 2.9 22.7 4.0 30.6 6.7 17.0 14.0 31.4 13.2 11.6 10.6 57.9 5.4 16.9 0.0 14.6 12.4 5.7 12.9 16.2 16.6 13.2 17.5 10.9 11.1 24.4 67.5 11.2 14.4 1.7 10.0 20.5 12.3 15.0 17.3 12.7 7.0 29.8 0.0 4.4 18.6 16.3 5.0 18.5 15.9 18.4 10.3 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 35000 Nucleoplasm Nucleoli "HPA040765: AB_2677125, HPA062187: AB_2684706" "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favorable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 12.4 17.9 18.1 15.5 19.2 24.2 21.1 20.1 20.2 19.4 16.4 18.4 21.1 12.7 17.2 24.3 25.4 19.1 15.9 17.6 17.5 21.8 15.9 19.4 15.9 23.7 20.0 11.8 31.4 16.7 11.9 17.4 15.5 23.0 19.5 16.6 16.3 13.8 15.8 13.4 14.7 15.7 16.8 23.2 20.2 15.7 18.2 13.0 26.3 23.7 19.4 25.5 28.6 13.6 23.4 21.7 18.7 14.1 20.6 20.6 10.7 8.0 7.1 22.1 9.6 17.3 37.2 7.2 12.8 13.9 14.8 15.0 5.2 15.2 7.7 13.6 13.8 17.4 10.6 7.7 15.6 13.3 16.3 18.5 32.5 19.9 35.1 8.9 31.1 16.5 13.5 15.3 12.1 19.1 25.0 9.8 15.3 25.7 18.9 18.8 12.8 23.9 24.8 13.5 8.1 11.5 9.1 12.4 12.1 19.4 12.4 9.2 8.5 12.9 12.3 20.6 27.1 10.2 14.2 13.4 21.3 12.1 12.6 10.5 20.7 19.6 36.3 16.3 13.9 13.5 18.7 12.7 12.7 12.7 10.8 18.5 23.4 15.6 13.7 21.7 18.9 19.1 20.6 3.0 20.6 14.1 17.9 20.1 10.7 18.1 19.2 20.1 20.2 17.5 21.8 20.0 11.8 23.0 13.0 0.0 11.5 24.3 38.6 28.2 12.5 17.8 17.8 21.4 11.4 15.7 9.8 45.1 48.0 20.2 14.8 15.7 12.9 0.0 14.0 44.2 34.2 17.7 25.4 15.7 41.6 3.2 9.1 16.0 41.1 2.7 33.9 45.8 27.0 23.4 25.0 17.1 18.9 24.6 26.5 45.3 10.5 19.4 29.4 36.5 22.3 40.5 25.7 32.6 29.2 23.7 PPIL4 ENSG00000131013 "Peptidylprolyl isomerase like 4" Q8WUA2 6 149504733-149546038 "Enzymes, Predicted intracellular proteins" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031599, HPA031600" Approved Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA031599: AB_2673950, HPA031600: AB_10600928" "unprognostic (6.12e-2)" "unprognostic (4.90e-2)" "unprognostic (3.85e-2)" "unprognostic (8.42e-2)" "unprognostic (7.53e-2)" "unprognostic (6.36e-3)" "unprognostic (2.91e-3)" "unprognostic (2.22e-1)" "unprognostic (4.22e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-1)" "unprognostic (4.62e-2)" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (8.50e-2)" "unprognostic (7.94e-2)" 20.0 20.1 20.6 15.0 35.5 30.6 21.2 35.1 27.8 24.0 15.3 19.7 10.1 14.1 21.1 27.2 15.7 18.0 19.8 18.3 21.3 15.6 18.8 23.0 17.9 15.7 20.9 18.0 32.9 16.0 20.8 36.6 22.6 23.9 20.5 16.8 15.7 18.2 16.7 14.8 15.4 16.0 20.0 22.7 17.6 16.0 15.9 19.4 27.0 26.8 8.2 16.8 22.0 19.2 21.4 16.6 24.9 17.8 28.7 24.6 14.8 11.1 6.0 21.0 17.3 12.5 16.4 19.6 22.0 21.0 24.1 25.7 12.6 11.4 11.8 15.2 16.9 14.4 10.1 16.0 8.4 38.3 17.1 15.1 13.0 13.2 21.6 19.7 23.6 11.1 12.8 14.4 24.6 20.6 13.5 13.1 8.6 28.3 7.1 18.7 11.9 13.4 20.3 16.6 11.2 9.5 18.2 19.4 5.9 18.3 8.5 12.4 9.5 26.2 11.5 15.0 15.2 13.5 17.2 15.3 16.0 12.5 28.3 20.9 9.4 4.8 18.5 13.5 19.0 23.0 24.9 16.1 18.1 14.7 17.8 20.4 21.4 19.5 16.9 16.6 16.6 24.6 18.7 13.4 28.7 16.1 16.2 20.7 14.8 20.6 35.5 35.1 27.8 21.3 15.6 20.9 18.0 23.9 19.4 62.5 64.3 22.6 54.3 43.4 44.2 33.3 17.8 80.3 61.4 43.6 7.9 43.1 36.5 34.7 17.2 37.3 15.2 0.0 23.1 37.9 55.5 27.1 73.0 18.7 31.8 27.0 22.3 30.7 21.3 9.6 57.2 29.9 38.8 47.7 19.7 40.0 26.4 22.9 52.6 27.5 35.5 51.8 68.4 58.2 53.4 39.5 54.6 41.5 20.0 32.7 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.5" "Group enriched" "Detected in many" 4 "Ciliated cells: 187.4;Early spermatids: 262.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 6.5;ASC diff: 10.4;ASC TERT1: 12.9;hTERT-RPE1: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.5 1.4 5.5 1.1 8.6 0.7 3.6 5.0 4.8 4.6 1.7 7.2 7.4 1.9 3.8 12.7 2.0 36.5 1.7 2.6 6.0 5.4 4.9 1.2 8.9 1.1 3.4 3.2 6.3 4.3 6.6 7.6 1.6 18.3 1.8 1.6 2.6 2.8 5.0 3.9 1.7 1.1 5.4 3.2 1.3 2.3 20.4 5.3 0.0 17.2 1.4 1.1 2.9 2.0 5.1 1.7 2.0 1.3 1.7 1.3 1.1 1.8 1.0 1.2 6.5 10.4 12.9 1.1 0.0 2.3 0.5 0.2 0.1 1.8 0.0 0.5 0.6 0.9 1.2 1.0 0.0 0.3 0.5 0.9 0.5 0.1 0.0 5.2 0.6 0.3 2.7 6.2 0.2 3.9 9.3 0.8 1.4 0.9 0.3 0.4 0.6 0.1 0.6 0.2 4.2 1.3 0.8 0.0 0.6 5.0 0.1 1.5 2.5 0.2 0.3 4.3 0.3 0.5 1.0 0.4 0.1 0.2 1.1 0.2 0.3 0.1 0.1 2.1 0.1 0.4 2.0 1.2 1.2 0.9 1.3 0.9 5.1 1.2 1.1 1.7 3.2 1.1 1.0 1.6 1.7 1.1 1.7 1.3 1.1 5.5 8.6 5.0 4.8 6.0 5.4 3.4 3.2 18.3 5.3 6.0 5.8 0.0 3.5 1.9 2.1 3.3 5.1 187.4 22.7 3.5 2.0 0.5 21.6 1.6 262.5 1.5 0.7 0.0 1.0 0.7 1.7 2.9 0.0 0.0 0.3 1.6 2.9 0.6 0.0 40.8 4.9 0.5 3.3 1.0 1.8 4.9 0.7 0.0 4.9 8.0 11.5 0.0 1.2 52.6 22.0 2.6 0.6 0.5 1.7 1.1 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 362.9;Late spermatids: 423.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" NA NA 850000 Cytosol "Plasma membrane" "HPA029209: AB_2672951" "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 16.2 11.7 13.8 15.0 18.3 64.0 15.1 20.5 28.6 15.5 32.4 13.3 9.4 19.1 17.4 12.7 15.2 10.7 10.8 37.1 13.5 16.1 22.8 26.7 14.6 11.8 15.6 19.1 12.1 13.3 18.2 12.2 15.8 24.3 16.5 19.4 12.3 18.7 13.5 56.1 16.7 25.2 15.0 13.8 11.6 14.9 29.7 12.7 23.4 13.3 11.6 13.4 15.2 16.5 4.0 2.7 8.0 2.1 4.7 4.5 1.9 48.6 11.0 9.6 8.1 14.7 13.6 12.2 13.4 15.7 10.0 9.5 6.2 14.4 29.3 12.8 15.1 7.4 10.8 9.9 13.8 17.5 26.3 5.6 18.0 7.8 9.6 12.3 20.4 12.9 11.5 16.6 11.7 16.0 11.7 9.7 15.0 9.9 23.3 12.1 21.3 26.5 4.8 9.0 9.7 9.3 9.5 22.2 9.4 12.0 23.4 16.3 12.2 13.9 16.3 11.3 9.1 16.4 8.9 13.4 20.8 20.8 9.1 9.5 18.2 10.3 34.3 9.5 8.1 10.5 6.7 1.8 5.1 3.5 1.8 3.8 1.7 2.8 3.1 2.7 4.0 2.2 2.1 8.0 4.7 2.1 1.6 4.5 1.9 13.8 18.3 20.5 28.6 13.5 16.1 15.6 19.1 24.3 12.7 14.9 23.5 24.8 36.4 68.7 40.5 85.1 38.2 9.4 15.9 36.6 60.9 27.7 28.2 22.7 362.9 29.7 97.1 70.0 21.2 20.1 41.4 73.1 26.5 65.2 24.8 55.6 58.3 21.5 27.7 423.8 39.1 33.5 57.3 16.2 52.8 37.7 29.2 66.2 49.1 73.2 62.7 38.8 44.2 46.9 24.8 72.0 61.4 35.5 36.5 38.6 PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol NA NA "Nucleoli, Cytosol" "HPA016745: AB_1855622" "unprognostic (5.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.96e-3)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.25e-1)" "unprognostic (6.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-2)" 23.7 13.8 31.2 12.2 33.8 24.7 15.2 32.6 25.2 16.3 18.2 26.0 13.6 13.2 15.7 20.4 14.9 12.7 14.3 21.1 29.6 24.6 19.4 27.7 13.4 16.6 34.6 22.4 15.8 20.9 34.6 17.9 12.1 22.9 20.7 19.0 24.3 16.4 16.4 72.0 12.5 14.3 21.1 27.3 16.1 14.8 13.3 34.1 19.1 15.0 13.1 16.8 18.2 15.9 6.5 5.5 11.1 5.0 4.7 9.5 1.6 17.0 15.3 20.4 14.8 25.4 11.9 23.1 13.2 15.3 13.8 12.2 20.5 11.1 18.8 20.8 15.3 11.2 9.3 22.7 8.7 20.4 18.9 8.8 19.8 9.1 14.1 20.6 17.7 16.6 11.4 15.2 10.9 18.6 10.8 11.2 8.8 14.4 20.0 12.3 14.2 17.5 28.5 25.1 15.8 5.2 18.6 22.7 12.6 32.1 17.3 16.4 20.7 11.9 17.9 15.3 31.7 9.7 12.4 10.2 12.1 17.4 10.0 12.7 17.5 11.4 17.6 6.4 29.5 8.7 8.3 3.3 11.1 7.2 4.5 6.2 5.8 6.9 6.1 5.5 6.5 9.5 6.4 9.2 4.7 5.0 5.3 6.2 1.6 31.2 33.8 32.6 24.9 29.6 24.6 34.6 22.4 22.9 34.1 17.9 17.3 29.6 37.1 53.8 47.2 45.6 28.1 5.3 20.5 38.4 60.9 27.6 39.7 35.0 59.2 17.3 39.4 0.0 41.1 24.4 27.3 58.6 26.5 49.9 23.3 101.7 38.6 16.5 48.5 32.9 33.1 41.2 54.0 37.9 27.4 54.4 35.2 40.3 31.8 30.8 128.5 25.8 38.7 33.8 26.0 54.5 54.0 54.2 32.8 45.7 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA022277: AB_1858839, HPA061848: " "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favorable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 12.2 7.0 6.1 5.7 9.2 13.6 11.9 30.8 6.6 11.1 10.0 10.6 7.8 7.6 12.0 8.3 8.6 11.1 8.3 5.8 7.7 4.4 7.4 7.4 9.2 7.9 10.3 4.6 17.3 12.3 8.1 8.9 18.5 8.8 9.3 9.4 8.2 8.1 6.8 9.7 8.1 8.1 8.2 7.3 9.2 7.3 16.2 12.5 15.5 8.7 6.9 7.0 7.8 11.3 7.3 13.1 20.5 13.2 6.8 8.3 6.8 2.7 5.5 6.2 5.3 4.2 2.6 8.0 4.3 2.9 2.8 4.0 5.6 1.6 7.9 3.6 3.0 1.1 3.0 4.0 1.8 3.8 1.4 8.8 5.7 5.4 6.5 3.5 2.3 4.4 2.3 2.9 4.2 2.5 2.3 6.4 3.4 4.1 3.3 3.0 26.9 6.2 3.4 2.7 2.6 4.3 7.6 7.9 4.7 2.5 3.4 8.5 6.2 5.7 1.9 1.3 6.9 2.3 3.1 4.7 3.7 10.1 2.8 2.3 5.4 5.7 6.0 1.5 2.3 2.8 8.2 13.2 14.1 6.7 10.2 5.9 7.3 5.6 6.1 13.1 5.9 6.1 6.2 20.5 6.8 6.1 5.8 8.3 6.8 6.1 9.2 30.8 6.6 7.7 4.4 10.3 4.6 8.8 12.5 29.8 7.7 13.7 4.0 18.7 12.0 5.6 5.1 2.7 4.5 5.2 3.9 13.6 3.3 6.0 51.4 15.8 10.1 0.0 6.0 5.1 11.2 6.9 1.1 2.8 7.5 3.2 13.8 20.3 23.0 8.1 12.7 9.8 3.3 6.4 9.0 6.4 5.1 8.6 7.1 4.2 10.1 0.0 12.0 24.5 13.9 15.7 32.3 7.5 10.5 5.5 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755869-58985176 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 10.7;brain: 36.5;testis: 13.1" "Cell type enhanced" "Detected in some" 19 "Bipolar cells: 16.0;Cone photoreceptor cells: 29.5;Early spermatids: 22.1;Horizontal cells: 73.1" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 25 "basophil: 2.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Cell line enhanced" "Detected in many" "AF22: 10.2;HAP1: 16.5;MOLT-4: 7.8;SCLC-21H: 7.6;SH-SY5Y: 15.8;THP-1: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Yes No Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.7 10.7 15.0 0.8 7.5 0.7 0.7 11.9 23.3 1.0 0.7 3.6 0.0 0.8 1.1 2.2 0.7 3.3 0.8 2.3 36.5 5.4 1.9 2.4 1.0 0.9 3.2 9.2 1.0 1.7 0.8 3.4 0.6 10.5 3.2 0.7 3.5 0.8 0.7 0.6 0.7 1.0 1.3 2.7 0.8 1.4 13.1 2.0 0.0 0.8 0.0 1.0 0.6 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.5 0.0 0.0 0.8 0.0 0.0 0.8 1.2 0.0 0.0 6.5 0.1 0.1 2.3 0.0 16.5 0.0 0.4 0.1 4.9 0.0 0.1 0.0 1.2 0.5 2.1 0.3 1.3 0.1 0.0 0.5 0.0 4.1 1.6 0.0 0.0 2.9 7.8 0.0 2.9 0.0 0.8 0.0 1.3 0.0 0.0 0.0 7.6 15.8 0.2 0.0 1.0 0.1 0.0 7.0 0.0 0.0 1.9 0.0 2.4 0.0 0.1 4.4 0.3 0.0 2.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 7.5 11.9 14.0 36.5 5.4 3.2 9.2 10.5 2.0 0.0 0.0 0.0 0.0 0.0 16.0 1.6 0.0 0.0 3.4 0.0 29.5 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.1 73.1 2.9 0.0 0.3 14.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.4 0.0 11.7 0.0 0.0 9.3 2.5 0.0 0.0 0.0 0.0 0.0 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919420-21952837 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Ito cells: 61.4;Kupffer cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.7" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 17.7;monocytes: 13.9" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 36.5;K-562: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 780000 Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 25.0 15.6 14.0 21.8 14.3 24.3 18.4 16.9 16.3 18.1 13.2 7.6 12.5 9.6 17.6 9.7 23.6 12.3 13.1 17.0 13.9 14.9 13.2 8.5 21.6 15.1 11.6 10.1 14.4 10.7 8.3 7.7 28.1 14.5 15.6 4.9 11.2 11.2 16.5 15.8 15.5 11.1 15.4 15.5 31.4 10.5 6.7 10.9 6.2 10.9 15.1 10.2 15.8 37.6 0.7 5.5 17.7 13.9 1.7 1.4 2.8 9.2 9.9 6.4 6.2 3.5 6.3 8.1 10.6 6.3 9.4 6.5 4.5 3.7 5.6 13.3 7.4 4.0 11.2 2.8 6.6 3.3 8.0 9.0 21.7 4.6 4.3 5.9 8.0 5.9 5.9 2.0 9.1 4.3 6.7 36.5 5.6 55.2 2.4 12.0 8.6 4.7 6.2 2.7 2.9 10.9 7.1 16.5 1.6 3.2 3.9 2.6 10.0 10.0 3.3 8.6 2.6 4.1 5.6 30.7 11.3 11.5 10.3 10.1 4.7 3.7 6.2 11.4 15.3 21.6 0.0 7.7 3.3 1.0 12.9 0.7 0.7 0.7 0.6 5.5 0.6 0.7 0.8 17.7 1.7 13.9 1.4 1.4 2.8 14.0 14.3 16.9 16.3 13.9 14.9 11.6 10.1 14.5 10.9 6.0 5.9 5.1 4.4 7.2 7.0 13.1 15.3 4.0 3.4 1.8 2.0 13.3 3.3 4.9 1.1 31.9 2.0 0.0 4.3 7.2 7.7 3.9 3.5 5.5 17.5 7.9 5.8 61.4 32.9 1.1 6.6 18.0 6.8 8.2 3.9 3.8 5.6 0.0 6.3 3.4 6.5 6.5 5.7 7.4 10.5 5.0 2.5 5.7 3.8 5.4 PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381194-27409687 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.3" "Cell type enhanced" "Detected in all" 17 "Early spermatids: 1236.5;Late spermatids: 2467.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "HPA035530: AB_10670021, HPA035531: AB_10610283" "unprognostic (7.50e-2)" "unprognostic (8.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (4.15e-2)" "prognostic unfavorable (3.14e-7)" "unprognostic (9.36e-3)" "unprognostic (7.73e-2)" "prognostic favorable (6.08e-5)" "unprognostic (3.74e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-3)" "unprognostic (1.06e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (7.83e-2)" 12.7 17.0 9.9 19.9 9.2 19.4 30.2 10.9 19.3 17.9 14.6 9.1 16.9 12.1 26.8 12.5 19.4 19.2 17.7 13.6 8.8 7.6 12.6 18.6 14.7 20.2 9.4 8.0 13.4 18.6 13.8 13.2 11.4 8.7 10.2 16.4 9.1 16.4 18.7 24.1 10.9 12.2 14.9 6.7 14.7 14.1 93.3 8.4 25.8 14.1 19.1 22.5 25.2 17.3 20.2 40.3 24.5 29.1 22.7 38.3 19.0 50.9 42.1 30.9 23.7 19.7 16.1 28.5 31.8 20.9 38.2 30.7 64.8 27.0 60.2 23.4 22.5 32.5 27.9 51.9 35.7 34.4 25.1 42.2 58.6 30.7 68.4 17.8 57.8 24.8 17.4 20.7 38.9 31.4 18.2 36.5 29.9 49.0 18.7 28.9 45.6 42.9 62.8 44.9 35.4 30.4 44.4 64.8 31.6 25.8 35.6 41.6 47.1 28.5 31.6 22.8 25.6 17.5 19.0 29.3 28.6 34.6 25.0 48.2 40.8 45.7 95.2 22.4 47.4 21.4 22.1 17.8 24.5 26.9 22.3 26.5 20.2 28.7 27.9 28.5 18.0 21.7 22.4 9.1 22.7 29.1 40.3 38.3 19.0 9.9 9.2 10.9 19.3 8.8 7.6 9.4 8.0 8.7 8.4 59.6 43.5 61.1 65.0 72.0 42.0 33.6 50.9 61.6 66.0 66.3 27.5 71.4 28.2 97.8 1236.5 66.3 54.6 23.3 120.2 139.9 42.7 66.0 58.8 37.8 76.1 46.1 77.4 35.6 49.4 2467.5 65.0 65.1 23.6 147.9 59.6 64.9 122.3 42.1 66.8 48.3 34.6 45.3 45.8 594.3 323.3 70.4 44.4 79.7 83.2 121.2 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 59.1" "Cell type enhanced" "Detected in all" 12 "Cardiomyocytes: 417.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 27.5;Karpas-707: 24.0;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria No No Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 3.6 6.1 19.2 8.8 17.2 5.9 9.3 21.1 26.8 12.9 3.8 12.5 2.5 3.0 21.8 5.5 7.6 14.1 6.0 59.1 23.1 14.6 11.8 5.1 6.5 14.5 21.6 15.9 22.0 7.3 10.4 8.4 6.4 17.0 11.1 4.3 4.7 7.1 5.3 8.3 1.9 6.7 18.2 15.0 10.9 5.4 12.3 19.4 7.3 5.4 1.9 15.8 6.5 8.1 31.8 38.8 5.5 3.4 7.9 16.1 7.1 2.2 0.7 2.8 5.0 4.3 5.6 1.1 3.5 6.4 11.8 14.0 5.7 0.5 27.5 3.9 2.2 5.7 0.2 8.4 2.7 4.7 21.2 3.5 4.9 2.2 5.1 3.3 6.7 2.6 3.7 1.3 7.2 6.3 2.4 1.9 11.9 7.3 24.0 3.4 3.1 8.8 3.7 1.7 1.6 1.1 5.0 4.7 10.5 4.1 0.9 2.2 1.9 2.2 0.2 2.6 4.9 11.4 1.9 0.4 4.1 2.1 1.3 2.0 7.6 6.9 23.0 4.5 5.5 6.8 5.5 2.9 2.3 12.4 3.4 16.1 30.4 11.8 12.4 5.5 31.8 11.7 14.1 0.9 7.9 0.9 38.8 13.3 7.1 19.2 17.2 21.1 26.8 23.1 14.6 21.6 15.9 17.0 19.4 44.7 11.3 104.3 16.5 8.8 97.4 417.4 7.6 24.1 17.0 47.1 17.7 9.4 132.6 5.9 6.1 17.6 2.0 46.7 5.4 2.6 28.3 31.2 18.5 22.1 23.1 81.0 9.2 20.3 11.1 6.2 22.2 13.9 20.3 111.0 15.6 19.2 6.3 4.9 29.7 39.1 14.1 25.8 38.7 35.6 21.3 4.6 2.4 54.8 2.9 5.7 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245793-52250597 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 38.2;Kupffer cells: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 26.2" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" NA NA "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: AB_2684740" "unprognostic (4.26e-3)" "prognostic favorable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favorable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 14.3 7.2 13.9 22.7 14.8 16.5 26.3 3.6 9.2 16.9 12.5 4.6 7.8 4.4 13.6 12.0 10.8 11.7 19.4 14.5 8.7 8.5 8.7 4.9 30.1 38.0 5.4 12.3 14.9 5.9 6.9 7.5 8.6 4.9 15.1 6.7 11.0 10.8 12.4 3.1 7.5 8.8 18.1 6.8 22.5 8.3 6.2 5.9 20.5 11.3 9.9 20.5 11.3 13.5 5.0 9.6 19.6 18.6 7.4 15.0 10.1 0.4 2.5 1.5 3.7 22.8 22.8 2.4 5.8 12.5 8.2 6.4 1.4 2.0 4.2 1.7 15.1 4.6 0.7 5.1 1.1 3.3 5.0 1.2 9.6 6.7 1.5 16.7 1.4 9.1 18.8 2.5 9.2 5.8 13.3 10.6 19.5 1.6 7.0 9.6 1.0 6.2 0.4 2.0 1.9 7.0 1.4 0.7 9.2 3.5 1.1 1.1 4.5 4.2 1.0 5.2 3.4 3.6 3.7 7.3 3.1 5.3 1.8 0.7 26.2 4.8 4.5 6.2 2.5 3.8 1.2 15.7 8.5 15.0 12.4 11.7 5.0 11.8 13.8 9.6 3.8 11.1 13.8 19.6 7.4 18.6 5.8 13.2 10.1 13.9 14.8 3.6 9.2 8.7 8.5 5.4 12.3 4.9 5.9 0.0 4.8 11.5 3.9 4.5 1.0 2.0 5.1 1.4 3.4 1.8 0.0 3.0 3.3 1.7 9.9 6.9 0.7 0.0 1.0 5.3 8.2 2.7 5.7 2.4 38.2 1.6 1.2 10.4 40.0 14.2 11.8 24.5 5.0 10.0 0.2 5.1 1.6 1.9 9.2 2.2 0.4 19.4 6.1 0.4 3.6 3.3 1.6 22.0 0.7 1.8 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398183-67421183 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 177.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 8100000 "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" 28.4 35.4 24.2 42.0 32.3 42.1 25.1 19.6 33.4 23.9 39.6 22.1 29.9 33.9 19.6 25.8 59.7 22.8 28.6 33.0 21.8 17.1 43.7 55.0 27.6 49.3 19.9 19.9 20.1 53.3 23.1 21.6 44.0 19.3 27.2 33.2 23.2 49.7 31.1 39.0 34.4 47.3 20.5 21.3 53.7 35.1 15.7 19.4 77.7 38.5 40.5 63.9 25.5 25.7 78.8 76.6 126.2 118.0 68.2 113.9 177.2 45.3 52.4 31.1 45.8 15.5 19.0 31.7 22.5 26.4 45.4 34.5 74.9 54.8 39.1 38.4 34.1 33.8 39.8 35.9 46.8 27.9 41.1 24.4 37.5 24.7 39.2 33.9 47.6 48.5 21.4 31.0 38.6 22.8 21.6 45.5 38.3 34.8 32.4 36.7 103.5 60.3 93.6 51.6 86.5 41.5 42.9 43.0 33.8 44.6 37.6 24.3 40.4 26.1 46.9 69.4 24.3 56.1 33.0 32.4 35.1 35.9 41.3 29.1 32.5 30.1 44.4 42.0 32.7 36.9 81.4 80.1 126.2 88.6 100.5 69.3 78.8 79.8 90.5 76.6 77.0 49.1 69.2 93.3 68.2 118.0 54.4 113.9 177.2 24.2 32.3 19.6 33.4 21.8 17.1 19.9 19.9 19.3 19.4 71.5 93.0 166.0 108.0 88.8 35.0 7.9 117.2 41.5 46.6 82.0 9.8 320.7 180.8 238.7 1.8 77.3 292.4 23.3 272.4 398.0 69.2 127.9 107.3 102.4 338.5 41.3 93.0 87.2 194.1 5.3 45.5 157.2 129.9 390.5 160.1 42.9 250.4 210.5 26.9 236.5 23.6 97.0 60.9 13.0 106.5 106.3 357.3 222.6 164.6 168.4 PPP1CB "PP-1B, PP1B, PP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7700000 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022558: , CAB069426: , HPA065425: AB_2685489" "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 28.5 22.6 30.0 20.5 37.6 29.5 32.4 19.1 29.8 51.1 39.3 21.1 30.7 24.4 58.0 31.8 86.0 37.0 33.3 67.1 27.8 27.9 32.0 20.0 35.3 22.3 27.4 24.4 39.7 21.9 48.9 28.7 42.3 22.0 46.4 27.7 25.2 36.5 38.6 99.6 25.1 30.0 100.8 27.5 25.2 31.4 25.5 21.4 28.1 27.5 32.9 25.3 82.1 50.5 15.6 25.4 41.5 42.7 23.5 28.3 17.9 37.1 23.4 81.7 25.2 28.0 26.1 47.6 20.0 22.8 19.5 19.3 20.7 22.0 29.7 25.1 20.6 21.6 23.0 23.2 26.7 23.2 47.1 12.0 22.5 28.8 22.4 61.0 25.4 10.6 20.0 38.0 21.0 44.0 20.5 23.5 15.8 20.4 29.5 25.5 18.6 26.9 22.0 26.8 28.6 18.6 26.4 72.4 22.6 63.3 44.9 22.4 27.7 31.0 34.6 27.1 24.4 16.7 14.2 28.1 26.1 28.7 18.6 24.0 21.1 33.1 60.9 27.7 27.4 19.3 22.5 24.8 32.1 16.8 37.8 21.3 15.6 25.5 19.6 25.4 13.4 22.7 25.5 41.5 23.5 42.7 19.6 28.3 17.9 30.0 37.6 19.1 29.8 27.8 27.9 27.4 24.4 22.0 21.4 86.4 80.7 105.5 134.5 437.2 53.8 298.4 104.4 129.8 72.8 294.8 25.5 104.9 207.2 242.7 375.6 106.2 128.9 163.5 183.3 167.5 182.4 291.0 146.3 81.8 104.3 154.1 271.6 108.6 144.9 304.1 182.1 233.4 318.9 92.8 133.9 100.9 238.2 181.4 283.9 113.6 53.2 620.9 265.8 57.5 61.8 400.4 328.6 110.8 99.3 394.6 PPP1CC "PP1C, PP1gamma" ENSG00000186298 "Protein phosphatase 1 catalytic subunit gamma" P36873 12 110719680-110742939 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 486.0;Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022645 Uncertain NA NA 7600000 "CAB022645: " "unprognostic (1.51e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.29e-2)" "unprognostic (7.26e-2)" "prognostic unfavorable (2.75e-6)" "unprognostic (6.55e-2)" "unprognostic (4.11e-2)" "unprognostic (6.91e-2)" "unprognostic (4.96e-3)" "unprognostic (5.72e-2)" "unprognostic (2.92e-3)" "unprognostic (1.66e-2)" "unprognostic (1.71e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" 23.3 29.4 27.4 23.4 29.8 28.8 24.1 31.9 32.3 25.2 63.3 22.2 15.4 63.0 25.9 19.8 31.3 22.9 21.5 66.5 29.4 21.0 19.8 20.6 19.6 41.4 32.0 21.9 31.7 38.8 19.6 25.8 17.0 25.9 26.1 36.4 28.7 26.9 19.4 63.4 24.0 73.3 46.3 25.9 27.1 25.2 43.7 28.3 42.3 25.9 18.3 41.3 37.9 23.2 17.8 19.1 30.8 19.1 8.5 14.9 12.5 45.8 27.7 47.4 34.6 28.8 39.8 36.3 26.5 39.5 44.1 35.3 47.3 23.4 71.8 20.1 28.4 27.6 26.2 63.5 34.8 61.7 41.7 42.8 46.4 20.8 48.2 23.5 59.0 40.4 25.1 28.5 33.3 29.8 46.9 50.9 40.8 46.2 19.5 40.3 19.1 47.7 66.2 74.6 30.3 41.0 47.0 32.7 45.4 28.2 34.9 38.3 30.8 29.2 35.2 51.0 43.6 55.1 46.2 22.6 22.5 37.3 30.3 33.2 30.7 31.9 61.5 21.2 43.0 34.2 18.7 19.1 30.8 8.2 14.9 8.0 17.8 14.9 11.7 19.1 15.4 12.4 10.2 16.3 8.5 18.8 7.4 13.7 12.5 27.4 29.8 31.9 32.3 29.4 21.0 32.0 21.9 25.9 28.3 32.8 25.1 131.3 108.1 185.8 159.6 121.9 61.1 12.0 21.6 34.9 64.8 118.3 79.6 59.1 486.0 77.6 126.9 70.0 109.1 164.3 97.7 101.2 58.7 34.2 118.8 96.9 81.6 50.3 154.1 696.0 83.1 84.6 121.4 49.5 90.9 76.2 74.1 147.3 130.4 66.8 93.8 109.9 130.8 168.8 41.4 183.6 110.5 92.7 142.6 110.4 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.0;skeletal muscle: 227.2" "Cell type enriched" "Detected in many" 5 "Distal tubular cells: 1142.3" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10 "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Group enriched" "Detected in some" 4 "ASC diff: 6.5;NTERA-2: 21.2;RPTEC TERT1: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB007811, HPA041542" Approved NA NA "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 67.0 2.1 9.9 1.6 33.2 1.3 51.8 2.2 8.2 1.6 4.0 2.9 0.5 2.2 1.7 1.8 4.3 1.6 1.9 34.6 6.6 3.7 35.4 27.5 1.3 1.4 6.4 4.8 3.3 5.6 3.9 0.1 1.2 4.8 2.9 1.8 0.1 3.1 2.3 227.2 1.3 2.4 2.3 2.7 1.3 4.7 1.7 7.8 0.0 1.4 16.6 1.4 1.4 4.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.9 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 21.2 0.0 0.0 0.0 0.0 0.1 23.4 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 33.2 2.2 8.2 6.6 3.7 6.4 4.8 4.8 7.8 0.0 0.0 1.9 0.0 0.1 0.7 215.5 2.5 0.0 0.0 17.4 0.0 0.0 1142.3 2.9 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 215.6 0.7 106.5 2.4 6.2 3.8 1.3 1.1 0.0 0.0 0.0 0.3 1.4 4.1 0.0 1.1 55.9 2.9 0.0 9.8 0.0 1.7 0.3 0.0 0.0 0.5 0.1 PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 173.9;salivary gland: 105.3" "Cell type enhanced" "Detected in many" 12 "Melanocytes: 128.2;Mucus-secreting cells: 299.8;Undifferentiated cells: 342.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "basal ganglia: 173.9" "Cell type enriched" "Detected in single" 37 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.6" "Cell line enhanced" "Detected in some" "ASC diff: 5.5;CAPAN-2: 8.7;HSkMC: 23.1;OE19: 10.7;SCLC-21H: 19.3" "Region enriched" "Detected in many" 8 "basal ganglia: 1113.7" "Region enriched" "Detected in all" 20 "basal ganglia: 1698.9" "CAB004026, HPA048630, HPA061142" Approved Approved NA NA "CAB004026: AB_2169007, HPA048630: AB_2680468, HPA061142: AB_2684438" "unprognostic (2.71e-1)" "unprognostic (4.09e-2)" "unprognostic (6.91e-3)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (7.69e-2)" "unprognostic (6.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.75e-2)" "unprognostic (6.13e-2)" "unprognostic (6.07e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.52e-3)" "unprognostic (1.55e-1)" 26.2 10.0 25.6 5.8 173.9 0.6 23.3 14.6 24.1 7.4 64.1 16.2 39.4 25.7 1.8 2.2 1.9 9.4 4.6 0.7 17.3 11.2 2.0 0.5 5.1 0.5 21.9 22.2 2.6 19.1 0.6 1.7 0.5 17.9 19.9 63.3 6.9 105.3 49.6 0.5 5.7 20.9 4.1 12.4 0.5 13.6 4.6 40.0 0.0 0.5 0.3 0.8 3.6 1.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 3.3 0.1 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.6 10.7 0.6 0.0 0.0 0.4 0.0 0.0 19.3 0.4 0.0 1.0 0.0 1.8 0.4 0.7 0.0 0.0 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 173.9 14.6 24.1 17.3 11.2 21.9 22.2 17.9 40.0 0.0 26.7 0.0 99.4 1.1 0.3 1.1 0.0 0.0 0.0 1.8 0.0 0.0 102.8 13.3 0.7 0.1 36.6 0.0 3.1 0.0 1.3 59.5 4.6 0.0 0.2 0.0 92.9 3.1 0.0 2.2 31.9 1.0 128.2 0.0 299.8 28.7 1.0 94.7 5.3 0.4 0.9 0.0 0.6 0.5 3.2 0.4 0.0 0.0 342.5 101.6 PPP1R2 "IPP2, PPP1R2A" ENSG00000184203 "Protein phosphatase 1 regulatory inhibitor subunit 2" P41236 3 195514425-195543386 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Early spermatids: 363.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 67.5" "HPA043729, HPA059420" Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA043729: AB_2678639, HPA059420: AB_2684009" "unprognostic (1.85e-2)" "unprognostic (3.71e-3)" "unprognostic (6.26e-2)" "unprognostic (3.58e-1)" "unprognostic (5.66e-2)" "unprognostic (1.44e-1)" "unprognostic (4.17e-2)" "unprognostic (3.92e-1)" "unprognostic (4.20e-2)" "unprognostic (2.00e-1)" "unprognostic (6.73e-2)" "unprognostic (8.32e-2)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (3.74e-1)" "unprognostic (2.71e-1)" "unprognostic (2.13e-1)" 16.4 12.7 19.9 17.7 26.0 45.2 18.3 16.2 22.9 16.1 21.2 11.4 17.4 19.5 18.9 20.7 25.6 15.3 15.8 23.3 18.6 21.7 16.7 13.0 21.7 30.4 16.5 15.4 17.1 12.0 9.5 17.6 16.1 21.2 17.0 16.0 13.7 15.0 19.0 57.1 14.1 22.6 17.7 15.4 24.2 13.9 21.8 7.0 38.1 19.1 25.2 23.5 26.5 15.5 26.0 26.6 63.2 16.9 22.8 50.2 30.1 11.6 2.5 4.3 4.9 7.3 7.8 7.9 7.3 10.6 7.8 6.7 39.5 5.3 4.6 29.2 8.9 8.4 5.2 4.5 7.4 9.6 9.1 8.5 5.3 4.2 13.2 11.3 5.5 5.5 9.5 5.7 5.8 11.8 6.2 6.7 4.9 4.0 9.9 6.8 8.1 9.8 6.2 4.5 14.0 11.8 4.6 7.5 13.7 9.3 8.9 10.2 5.6 8.8 9.7 13.1 8.3 15.3 5.6 7.4 5.0 5.8 8.2 9.9 67.5 29.3 22.1 7.0 10.1 9.7 26.3 16.7 63.2 19.6 16.9 26.9 26.0 41.2 27.0 17.6 23.6 50.2 34.0 39.4 22.8 16.4 26.6 41.7 30.1 19.9 26.0 16.2 22.9 18.6 21.7 16.5 15.4 21.2 7.0 20.8 39.2 125.0 121.2 83.7 47.5 46.2 25.5 66.9 38.7 21.0 55.0 57.7 106.1 61.4 363.0 65.1 53.1 46.7 57.9 34.5 51.3 104.3 109.6 24.6 55.6 49.3 55.0 39.3 59.0 190.1 47.8 82.0 92.8 141.5 44.1 50.2 58.5 55.2 59.8 82.6 79.3 25.8 64.1 239.4 84.1 67.9 86.3 140.6 44.9 143.1 PPP1R3A "GM, PPP1R3" ENSG00000154415 "Protein phosphatase 1 regulatory subunit 3A" Q16821 7 113876777-114075920 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "heart muscle: 24.1;skeletal muscle: 69.4;tongue: 75.4" "Cell type enriched" "Detected in some" 13 "Cardiomyocytes: 136.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 64 "THP-1: 18.1" "Region enriched" "Detected in single" 19 "thalamus: 1.2" "Not detected" "Not detected" "HPA070440, HPA073138" Enhanced NA NA "HPA070440: , HPA073138: " "unprognostic (8.96e-3)" 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.7 0.0 0.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 1.4 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 75.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 PPP1R3C "PPP1R5, PTG" ENSG00000119938 "Protein phosphatase 1 regulatory subunit 3C" Q9UQK1 10 91628442-91633054 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 259.9" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 213.5;Hepatocytes: 61.4;Muller glia cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 16.4;HHSteC: 20.8;hTERT-RPE1: 33.7;LHCN-M2: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027041 Uncertain NA NA "HPA027041: AB_1855649" "unprognostic (2.11e-1)" "unprognostic (1.86e-3)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.15e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.38e-2)" "unprognostic (1.85e-2)" "unprognostic (1.75e-3)" "unprognostic (5.63e-3)" "unprognostic (1.59e-2)" "unprognostic (5.48e-3)" "unprognostic (8.44e-3)" "unprognostic (4.86e-2)" "unprognostic (2.49e-1)" "unprognostic (4.61e-3)" 4.0 5.4 10.4 2.8 18.9 1.5 3.5 1.1 15.8 24.9 4.1 8.0 8.3 2.7 7.1 6.5 26.5 4.5 6.0 53.3 13.1 5.7 5.4 39.5 5.4 1.8 6.1 8.1 6.6 5.6 2.8 1.7 6.3 12.2 11.0 2.8 4.5 10.0 13.4 259.9 4.4 2.2 14.8 9.1 2.2 5.2 2.2 6.1 0.0 2.4 28.2 7.7 11.4 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.7 10.4 4.7 2.2 0.0 11.4 8.9 4.7 5.1 0.0 0.8 0.0 0.4 10.7 1.9 0.6 0.2 1.2 8.7 0.0 0.0 0.1 16.4 1.8 20.8 0.0 0.0 7.6 2.0 3.0 0.1 33.7 1.1 0.0 5.3 0.0 39.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.4 10.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 1.7 7.8 2.1 2.1 2.7 1.6 0.0 0.2 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 18.9 1.1 15.8 13.1 5.7 6.1 8.1 12.2 6.1 0.0 0.0 0.0 10.2 4.0 8.9 213.5 0.0 0.0 0.0 3.5 0.0 0.1 6.6 1.7 0.0 3.5 0.0 0.0 10.2 0.2 6.6 3.2 0.0 61.4 1.1 17.5 9.7 1.8 2.4 0.0 2.6 0.0 11.8 0.0 0.0 120.0 6.4 0.0 7.1 1.6 12.5 0.0 21.7 0.2 1.4 3.4 0.2 0.0 0.0 0.9 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194334-134226142 "Enzymes, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved NA NA "CAB003848: AB_562203, HPA043236: AB_2678379" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 26.0 30.5 37.6 22.0 41.0 57.9 26.0 54.2 56.6 23.0 27.3 29.6 15.6 24.8 29.8 20.4 39.6 21.9 24.7 47.9 39.8 38.1 31.7 33.2 22.7 29.1 35.0 35.8 23.4 23.9 44.5 20.6 44.0 47.5 22.3 26.4 18.4 23.6 23.7 43.1 32.6 26.5 31.6 32.8 30.4 21.8 18.8 24.1 45.6 33.2 30.5 39.9 26.9 24.5 29.2 41.1 39.0 33.4 38.9 37.5 43.8 37.9 32.0 45.7 24.6 23.9 25.7 32.1 35.9 30.8 54.7 55.3 61.3 29.8 33.3 33.8 33.1 62.0 19.8 43.9 51.8 64.1 30.1 25.1 23.6 37.4 38.1 35.4 23.3 21.4 23.8 35.9 42.8 42.7 27.3 38.3 33.7 23.2 25.0 41.4 27.3 36.9 22.7 25.0 30.2 19.3 33.1 45.5 32.3 32.9 42.8 36.5 25.4 37.0 13.8 40.2 47.8 28.2 27.6 26.9 31.6 17.8 25.3 50.5 22.5 40.2 52.6 21.3 30.9 32.6 20.3 33.4 39.0 26.7 33.0 34.1 29.2 30.7 35.6 41.1 28.6 35.7 32.7 38.7 38.9 33.3 22.0 37.5 43.8 37.6 41.0 54.2 56.6 39.8 38.1 35.0 35.8 47.5 24.1 47.6 47.1 62.7 174.1 212.2 43.8 101.7 71.4 50.9 51.2 54.1 21.6 139.8 91.2 89.5 23.5 75.5 59.4 70.0 77.0 143.4 86.8 121.4 62.2 58.2 98.2 47.7 83.5 49.7 91.0 21.8 35.6 80.0 99.5 125.4 51.7 61.5 82.5 50.1 42.8 83.6 24.4 19.4 109.5 69.9 85.0 204.9 259.0 79.8 56.2 157.9 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Peritubular cells: 248.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB018600: AB_675841, HPA043236: AB_2678379" "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favorable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 26.7 21.0 61.3 11.9 54.9 2.6 28.7 32.0 46.2 28.8 24.1 30.7 19.4 21.7 34.5 37.5 29.7 28.2 23.1 27.2 57.3 43.7 41.0 35.7 27.7 8.4 52.6 39.8 48.0 22.9 33.7 14.8 27.4 47.7 23.7 24.5 12.5 19.5 29.1 27.4 18.0 31.2 39.0 49.7 15.0 18.9 18.8 48.2 6.3 44.5 14.0 14.0 17.7 34.3 5.8 7.9 5.1 6.5 7.3 4.8 1.7 22.1 19.4 33.9 12.9 33.9 30.9 18.9 29.7 27.8 30.8 32.3 20.3 16.3 10.8 29.2 39.5 29.5 13.4 20.2 34.1 41.6 6.7 10.6 14.4 13.2 20.4 38.9 6.4 8.2 27.2 39.0 26.0 29.2 31.3 36.9 18.1 22.3 11.5 51.9 10.9 17.5 8.2 24.7 33.5 11.2 12.3 13.6 8.0 41.2 18.0 32.6 13.5 13.7 14.6 28.6 39.5 8.0 11.0 38.7 26.6 20.0 8.7 24.5 5.9 7.7 12.8 22.8 6.0 34.0 4.8 5.0 3.3 4.2 6.5 4.8 5.8 3.8 4.2 3.5 2.7 3.8 4.6 5.1 7.3 3.0 7.9 2.8 1.7 61.3 54.9 32.0 46.2 57.3 43.7 52.6 39.8 47.7 48.2 65.5 53.8 13.8 81.2 92.5 34.5 71.2 40.8 34.8 50.0 82.0 29.5 36.8 39.7 34.2 13.3 49.6 112.3 0.0 42.0 43.1 62.0 108.1 17.3 81.5 48.8 44.5 31.0 101.3 52.3 13.4 67.9 30.8 38.8 16.2 51.0 105.4 64.5 41.8 248.2 63.4 21.1 45.3 59.7 30.2 35.8 83.6 59.0 14.0 32.4 132.7 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190039-52229533 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 3400000 Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 25.3 57.3 60.7 20.5 71.0 18.0 21.4 47.5 82.1 29.6 31.2 26.6 21.5 33.4 26.4 37.9 37.7 47.0 39.9 74.7 70.2 44.8 31.0 29.3 20.0 27.5 44.0 50.9 45.8 24.3 37.8 29.5 24.6 51.0 31.0 29.8 31.0 24.3 35.6 50.6 33.5 25.3 34.5 25.2 20.5 19.8 21.7 18.1 29.0 28.9 35.9 30.6 27.3 23.1 52.8 62.8 51.9 67.2 69.8 56.3 67.8 30.9 52.6 42.0 37.3 34.2 35.8 22.1 26.1 34.2 34.9 30.6 26.4 24.5 27.1 18.8 41.5 19.2 22.4 45.0 39.4 20.3 20.0 121.9 19.9 29.0 29.7 31.3 21.5 19.0 48.0 32.6 32.7 30.1 32.8 33.1 18.2 23.1 19.1 38.7 35.8 30.0 41.0 41.5 31.2 46.5 29.5 24.4 30.3 56.1 51.0 31.7 33.9 32.0 32.0 19.5 28.6 28.9 38.0 31.4 27.7 25.1 13.5 29.8 19.8 29.0 31.8 29.8 21.8 34.9 45.0 55.3 51.9 50.4 67.2 45.8 48.4 45.1 47.1 62.8 52.8 37.7 43.0 33.7 69.8 59.8 39.0 56.3 67.8 60.7 71.0 47.5 82.1 70.2 44.8 44.0 50.9 51.0 18.1 41.7 30.7 69.2 78.9 62.5 111.3 81.8 68.8 52.2 36.4 113.4 23.6 183.6 99.5 195.0 3.8 51.7 133.3 0.0 136.1 214.1 70.0 78.9 68.0 44.8 127.2 136.7 102.6 66.9 55.1 6.8 67.0 47.0 50.6 131.7 108.9 97.9 137.7 175.6 80.2 103.3 48.5 77.6 81.4 14.8 54.1 55.3 152.2 70.3 147.4 93.1 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.9" "Group enriched" "Detected in all" 5 "Early spermatids: 249.6;Hepatocytes: 68.4;Late spermatids: 93.2;Spermatocytes: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 31.6 7.2 7.1 7.6 9.8 7.7 13.5 14.8 7.1 7.9 8.2 13.6 5.7 7.7 6.3 5.6 7.9 5.0 7.8 4.6 7.4 5.0 10.3 94.9 5.4 6.2 12.6 3.4 8.7 18.5 5.4 19.4 6.7 9.8 4.6 8.5 6.6 8.8 4.0 6.2 6.7 9.4 5.9 8.7 4.2 11.9 28.6 13.9 10.1 6.1 7.2 9.4 6.0 5.1 11.5 14.7 9.9 11.9 14.1 14.3 12.0 13.0 8.8 12.7 8.6 12.8 6.9 12.8 13.0 9.1 9.7 8.9 29.7 13.8 16.6 9.8 8.4 9.2 12.4 18.8 10.7 12.4 11.5 5.8 16.2 5.2 12.9 6.3 18.9 12.9 7.8 6.5 10.9 8.0 6.8 11.9 17.4 19.6 22.1 10.6 4.2 20.4 7.7 15.6 14.2 9.6 15.7 8.4 20.3 14.4 14.5 4.1 11.3 11.6 10.7 2.1 14.3 12.4 7.1 12.8 11.3 13.7 5.6 8.2 2.3 5.8 60.8 4.0 22.1 14.3 5.4 10.0 9.9 13.7 11.9 13.4 10.4 13.9 12.7 14.7 11.5 12.3 13.1 2.5 14.1 10.7 6.3 14.3 12.0 7.1 9.8 14.8 7.1 7.4 5.0 12.6 3.4 9.8 13.9 17.9 8.0 12.6 9.8 12.7 4.9 3.0 10.2 16.0 6.8 12.2 7.9 11.5 11.6 16.5 249.6 12.3 16.1 23.3 20.0 14.9 9.4 9.7 8.1 68.4 8.4 1.6 15.0 8.6 7.8 93.2 6.1 5.6 8.5 11.8 11.5 9.1 21.0 7.0 7.1 15.9 10.5 12.9 9.5 71.5 18.5 12.8 14.8 7.5 11.5 13.6 PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291491-26372680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol NA NA Cytosol "CAB079289: AB_659890, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (1.17e-1)" "unprognostic (2.68e-2)" "unprognostic (4.29e-3)" "unprognostic (5.34e-2)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "unprognostic (4.64e-3)" "unprognostic (3.65e-1)" "unprognostic (2.48e-1)" "unprognostic (3.87e-2)" "unprognostic (2.71e-2)" "unprognostic (8.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-1)" "unprognostic (3.44e-2)" "unprognostic (1.16e-1)" 26.1 14.8 25.1 19.1 30.3 21.2 41.7 23.7 28.0 25.2 18.2 27.9 16.0 23.4 20.5 16.0 50.3 19.1 16.8 24.6 21.2 16.2 21.5 32.0 21.7 17.6 28.9 22.3 22.5 13.3 19.3 18.3 39.4 24.8 20.6 18.4 11.3 24.3 18.3 41.6 31.7 16.2 21.1 22.6 15.9 15.3 19.2 32.1 18.3 21.6 29.1 30.4 21.8 29.9 8.0 4.8 6.5 4.8 7.9 10.1 3.6 18.9 18.4 23.8 17.0 14.9 21.3 25.4 29.6 19.0 27.8 26.7 22.6 14.1 26.2 9.0 15.8 18.3 22.8 28.7 24.0 38.1 11.5 15.1 19.8 18.4 11.9 23.5 11.4 15.4 16.9 34.0 24.0 33.4 18.2 43.2 14.8 27.0 25.5 25.3 12.1 25.9 12.7 31.4 45.1 13.0 18.6 17.8 21.8 17.4 28.7 10.0 13.1 14.2 14.3 23.1 22.9 15.1 10.3 23.2 17.4 21.6 17.7 20.7 9.3 12.1 33.9 20.7 20.8 29.3 3.1 2.3 6.1 4.3 4.4 5.4 8.0 6.0 7.6 4.3 6.8 6.1 7.9 6.5 7.9 4.8 4.8 10.1 3.6 25.1 30.3 23.7 28.0 21.2 16.2 28.9 22.3 24.8 32.1 68.5 57.4 46.7 211.9 121.3 52.2 30.0 30.6 123.1 100.1 14.0 45.2 66.8 41.4 40.1 32.5 64.2 45.3 70.0 28.2 56.0 37.8 125.3 54.3 29.2 32.0 35.0 73.7 52.2 31.3 86.3 43.4 50.2 57.3 42.3 32.7 48.8 45.2 26.2 68.9 36.8 37.6 51.8 57.7 28.9 62.2 125.0 56.0 43.7 33.3 178.5 PPP2R2B "B55beta, PR52B, PR55-BETA, SCA12" ENSG00000156475 "Protein phosphatase 2 regulatory subunit Bbeta" Q00005 5 146581146-147084784 "Disease related genes, Predicted intracellular proteins" Apoptosis "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 73.2" "Cell type enhanced" "Detected in many" 20 "Cone photoreceptor cells: 141.4;Early spermatids: 312.5;Late spermatids: 670.1;Rod photoreceptor cells: 261.9" "Cancer enriched" "Detected in some" 8 "glioma: 7.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 15.1;MAIT T-cell: 13.8;memory CD4 T-cell: 7.1;memory CD8 T-cell: 16.1;naive CD8 T-cell: 12.0;NK-cell: 9.5;T-reg: 8.0" "Group enriched" "Detected in many" 33 "NK-cells: 9.5;T-cells: 16.1" "Cell line enriched" "Detected in some" 4 "HDLM-2: 47.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038118, HPA042122, HPA042770" Approved Uncertain Cytosol NA NA Cytosol "HPA038118: AB_10697238, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (4.54e-5)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (2.80e-4)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.76e-1)" "unprognostic (1.84e-2)" "unprognostic (2.68e-1)" "unprognostic (3.20e-2)" "unprognostic (9.73e-4)" "unprognostic (4.51e-2)" "unprognostic (1.49e-8)" "unprognostic (2.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.48e-5)" "unprognostic (1.14e-4)" 2.0 9.7 30.8 2.5 35.2 2.9 1.8 10.2 73.2 1.6 2.7 26.0 0.0 3.0 1.7 1.8 2.9 14.5 2.9 2.9 26.4 20.9 4.7 2.4 2.5 4.3 25.5 22.4 1.6 2.9 16.0 6.4 2.6 27.5 2.7 2.8 4.6 2.0 2.9 1.5 4.9 2.3 3.5 18.6 2.9 2.2 15.7 29.3 0.0 4.2 0.0 2.4 6.8 1.1 0.0 0.0 0.3 0.0 9.5 16.1 4.1 0.4 0.4 2.4 1.0 0.1 0.1 0.2 0.5 0.2 1.1 1.6 1.3 4.8 0.2 0.1 0.0 0.0 10.2 0.8 1.0 1.1 47.5 0.2 0.6 2.8 0.5 0.2 0.0 0.2 0.1 0.7 0.0 0.2 0.7 0.1 0.4 0.6 0.5 0.7 0.3 0.0 0.0 6.3 0.0 1.1 0.7 0.1 0.1 4.2 10.9 1.9 0.2 0.3 0.0 0.2 1.7 0.4 0.1 0.3 0.2 0.7 2.5 0.4 0.4 0.2 0.0 1.7 4.3 1.4 0.2 0.0 0.0 15.1 0.0 13.8 0.0 7.1 16.1 0.0 0.0 1.3 12.0 0.3 9.5 0.0 0.0 8.0 4.1 30.8 35.2 10.2 34.1 26.4 20.9 25.5 22.4 27.5 29.3 3.0 2.6 0.0 1.1 1.8 83.2 1.2 12.7 0.0 1.2 8.7 141.4 14.1 18.3 1.3 312.5 2.1 0.0 0.0 0.0 0.2 1.1 0.2 0.0 0.0 0.8 44.5 12.5 0.0 1.2 670.1 3.1 1.7 5.0 0.0 0.0 31.8 0.8 0.0 2.1 4.0 261.9 0.0 8.6 3.7 1.6 1.3 4.5 16.7 0.0 0.7 PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4" "Group enriched" "Detected in some" 5 "Early spermatids: 52.2;Late spermatids: 144.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 14.2;A549: 21.0;CAPAN-2: 14.0;GAMG: 34.1;MCF7: 17.3;PC-3: 19.9;SCLC-21H: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA Cytosol "HPA042122: AB_2677859, HPA042770: AB_2678155, HPA060473: AB_2684291" "unprognostic (9.39e-2)" "unprognostic (7.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "unprognostic (2.70e-4)" "prognostic unfavorable (4.94e-4)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (1.36e-13)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.66e-3)" "unprognostic (9.90e-3)" 1.5 6.6 28.2 1.6 33.9 1.1 2.4 17.0 78.4 11.8 1.5 13.8 0.5 1.7 25.3 7.0 25.2 10.5 1.4 1.9 25.8 19.5 1.2 1.1 1.1 1.3 25.6 19.3 1.3 1.7 1.1 5.9 1.1 19.1 5.5 1.4 0.4 1.4 14.4 1.7 28.8 2.0 11.8 32.0 1.3 1.9 4.7 13.5 0.0 1.1 3.9 3.6 1.5 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.2 21.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 9.2 0.0 34.1 6.6 10.3 0.3 0.0 0.0 1.2 0.0 1.4 1.6 0.3 0.0 0.0 3.0 5.5 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.8 17.3 0.0 0.0 1.0 0.3 19.9 0.0 0.0 0.6 0.0 0.0 19.3 3.6 0.6 0.0 0.0 0.6 8.9 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 33.9 17.0 40.2 25.8 19.5 25.6 19.3 19.1 13.5 0.0 0.0 0.0 0.5 13.1 10.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.2 0.1 0.0 0.0 0.2 0.0 0.2 1.2 0.0 0.0 0.1 3.2 0.0 0.0 0.0 144.3 6.4 0.0 0.0 0.0 0.0 4.1 1.3 0.0 4.2 0.0 2.4 0.0 1.4 1.0 0.9 19.3 0.0 0.0 0.0 0.1 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965673-136147891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.6" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 102.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 19.2;BJ hTERT+: 18.8;RPTEC TERT1: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: AB_2685475" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favorable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.91e-4)" 6.3 3.3 3.4 1.9 6.4 0.7 4.3 1.5 4.9 5.5 6.7 5.2 5.8 1.7 6.8 5.1 5.0 3.0 3.3 27.4 3.9 2.8 31.7 1.2 2.6 0.9 7.0 4.4 3.7 3.8 7.5 3.7 9.0 5.3 3.8 3.5 1.6 7.7 7.8 85.6 10.4 2.5 11.4 6.1 1.2 5.2 4.2 6.5 0.0 2.3 31.6 1.2 6.5 3.9 1.5 1.8 1.7 1.4 1.8 1.5 0.6 19.2 1.1 5.5 2.6 4.5 5.7 6.4 15.1 18.8 7.1 8.9 1.2 1.2 0.0 5.8 15.4 5.1 2.5 2.3 5.3 15.5 0.0 0.7 0.8 0.6 0.0 3.2 0.0 0.8 5.1 4.6 9.1 4.3 7.2 6.8 0.5 0.5 0.0 10.2 3.2 0.1 0.1 3.8 0.2 3.7 0.0 8.1 0.0 25.0 0.7 0.4 3.1 2.4 3.0 5.8 5.2 4.8 0.2 4.4 7.5 4.1 10.1 6.6 0.2 0.5 0.0 5.5 0.4 2.6 1.1 1.2 1.5 0.9 1.4 0.5 0.7 1.0 0.8 1.1 1.5 1.5 1.2 1.7 1.8 1.2 1.8 0.7 0.6 3.4 6.4 1.5 4.9 3.9 2.8 7.0 4.4 5.3 6.5 26.8 22.2 2.7 15.3 23.5 4.1 102.3 0.0 9.4 11.4 52.4 0.0 7.6 18.3 18.1 6.1 8.7 15.8 0.0 8.5 13.2 12.8 12.5 3.5 2.4 2.2 3.2 12.5 5.5 2.1 9.5 22.7 4.6 27.0 14.4 7.9 9.5 12.6 9.9 17.3 37.2 2.2 6.5 11.9 6.6 19.6 29.1 8.7 3.8 7.3 15.3 PPP2R3B "PPP2R3L, PPP2R3LY, PR48, PR70" ENSG00000167393 "Protein phosphatase 2 regulatory subunit B''beta" Q9Y5P8 X 333963-386955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 43.5" "Cell type enhanced" "Detected in many" 11 "Cardiomyocytes: 62.0;Cone photoreceptor cells: 25.5;Spermatogonia: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 15.5;U-698: 24.3" "Low region specificity" "Detected in all" HPA026606 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA026606: " "unprognostic (1.25e-1)" "unprognostic (4.35e-3)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (6.03e-2)" "unprognostic (2.46e-3)" "unprognostic (1.56e-2)" "unprognostic (2.73e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-2)" "prognostic favorable (2.92e-5)" "unprognostic (4.65e-2)" "unprognostic (2.29e-8)" "unprognostic (1.15e-1)" "unprognostic (4.97e-2)" "unprognostic (3.17e-1)" "prognostic favorable (1.90e-5)" 1.8 1.3 8.8 1.1 11.7 3.8 4.8 9.1 8.7 7.6 1.2 0.0 0.0 1.4 6.6 0.7 2.4 2.3 1.4 17.7 12.2 2.9 4.1 1.1 1.5 1.7 15.4 6.2 6.9 2.9 1.5 11.0 8.9 13.0 2.4 0.7 0.0 1.6 1.2 43.5 3.9 1.3 1.6 8.3 1.8 1.8 4.1 15.0 0.0 1.0 0.0 0.9 2.9 2.6 0.1 0.6 2.3 0.1 0.0 1.3 0.1 0.5 5.3 0.7 2.2 0.1 0.2 7.1 5.9 1.5 5.3 6.3 5.3 0.0 0.0 3.2 4.5 0.6 0.0 0.2 0.0 1.4 3.7 4.3 1.2 1.8 0.2 0.0 1.9 2.2 0.1 0.1 0.0 3.2 0.2 0.1 3.2 1.0 0.3 1.2 2.6 9.0 7.8 2.3 0.1 15.5 4.1 3.4 0.3 1.4 1.5 0.0 9.2 0.0 0.9 4.2 4.2 0.0 2.3 0.3 3.1 2.9 0.0 2.0 0.0 0.0 24.3 0.1 2.7 3.9 0.0 0.0 2.3 0.1 0.1 1.3 0.1 0.1 0.0 0.6 0.1 0.3 0.3 0.1 0.0 0.1 0.5 0.0 0.1 8.8 11.7 9.1 8.7 12.2 2.9 15.4 6.2 13.0 15.0 0.0 1.7 0.9 7.8 6.1 11.5 62.0 2.5 2.7 1.2 0.0 25.5 5.6 0.0 2.8 0.5 3.5 1.4 0.0 3.5 5.6 3.0 2.2 0.0 1.0 3.2 6.4 4.6 4.3 2.1 1.5 3.7 5.3 5.0 3.6 3.8 11.2 2.6 0.0 2.8 1.3 19.8 0.0 3.8 12.9 25.5 6.6 3.3 1.9 3.1 3.9 PPP3CA "CALN, CALNA, CNA1, PPP2B" ENSG00000138814 "Protein phosphatase 3 catalytic subunit alpha" Q08209 4 101023409-101348278 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Craniosynostosis, Disease mutation, Dwarfism, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "prostate cancer: 98.1" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012778, CAB018581" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 35000 Nucleoplasm Cytosol "CAB018581: AB_2168324, HPA012778: AB_1855660" "unprognostic (6.66e-2)" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.56e-1)" "unprognostic (7.81e-2)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "unprognostic (7.87e-2)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (5.12e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-2)" "unprognostic (5.74e-2)" 12.2 9.2 22.7 7.4 71.8 7.7 10.6 42.1 52.4 9.4 9.5 4.8 9.8 5.8 6.2 6.9 7.4 7.2 6.8 4.3 36.0 13.5 5.8 8.4 10.0 6.7 10.1 22.1 9.6 4.7 7.0 4.2 6.6 11.9 34.6 8.4 2.6 10.4 21.1 23.7 11.4 6.4 7.9 7.5 6.9 11.0 5.3 13.0 3.8 6.8 6.8 8.9 8.4 6.8 27.7 18.3 44.3 14.9 22.3 15.5 6.6 19.4 13.8 3.8 7.5 21.6 16.4 7.4 21.5 19.8 8.7 9.2 8.0 24.4 9.3 9.0 19.4 10.8 9.8 13.9 28.6 14.8 22.7 6.4 14.7 19.8 10.2 15.9 23.6 7.5 17.0 15.0 19.0 21.8 16.6 16.3 6.0 5.7 25.6 13.9 23.4 4.9 17.7 6.4 22.5 9.0 9.0 35.0 10.7 8.4 15.4 30.4 11.5 17.7 15.2 10.3 5.5 13.6 13.5 19.0 20.6 23.5 18.8 14.2 12.0 12.2 16.4 11.4 13.4 5.5 24.6 11.8 24.8 13.6 11.4 15.5 27.7 12.9 13.1 9.9 23.4 6.2 12.3 44.3 22.3 14.9 18.3 8.6 6.6 22.7 71.8 42.1 51.5 36.0 13.5 10.1 22.1 11.9 13.0 71.5 48.8 59.1 33.3 149.9 74.7 24.1 33.1 32.1 20.5 29.6 37.3 28.9 28.2 18.2 1.8 105.6 33.9 0.0 27.3 76.5 53.9 157.6 33.6 37.0 32.1 17.5 122.2 43.6 52.2 4.7 60.1 49.5 87.7 44.1 39.6 19.3 41.1 107.8 57.3 31.7 81.9 12.9 39.4 7.2 22.1 150.4 23.0 55.4 39.9 32.0 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436428-73496024 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 133.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria NA NA Mitochondria "HPA008233: AB_1855661, HPA008823: AB_2668148" "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavorable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 17.3 16.1 40.0 11.7 36.3 7.6 22.5 44.5 42.7 13.4 16.1 7.9 9.5 10.1 17.0 15.0 14.0 12.3 12.0 16.7 39.7 20.5 11.9 9.1 9.8 13.1 18.2 40.7 17.2 10.5 19.3 16.8 10.6 21.1 16.8 12.8 9.5 10.4 17.6 133.0 10.9 9.4 23.0 18.1 10.0 10.7 11.6 11.9 8.4 10.1 10.0 14.3 14.1 14.4 4.2 5.7 4.8 3.8 4.5 10.6 2.7 19.1 10.6 19.0 19.6 27.3 37.9 9.1 17.6 24.2 17.3 17.2 6.7 9.8 17.0 5.7 25.4 8.2 10.3 15.3 13.5 24.4 23.8 12.5 7.2 9.6 12.7 16.3 16.0 15.1 26.8 16.3 16.3 21.9 31.9 11.9 14.9 9.0 20.0 34.8 6.0 14.3 14.8 7.7 8.4 31.0 9.6 10.3 8.0 16.8 9.3 10.2 11.8 10.3 25.8 12.9 16.5 19.4 15.5 13.0 13.8 12.7 11.0 23.8 13.4 36.5 11.9 17.1 23.1 7.8 3.2 2.9 4.8 6.2 3.8 7.3 4.2 6.7 6.6 3.0 3.0 5.3 7.9 1.7 4.5 2.3 5.7 10.6 2.7 40.0 36.3 44.5 42.7 39.7 20.5 18.2 40.7 21.1 11.9 3.0 11.0 18.2 26.7 22.8 52.0 42.6 10.2 13.4 11.4 17.4 19.6 17.9 53.0 15.6 5.9 18.3 10.2 0.0 16.6 13.6 21.4 23.8 20.7 12.3 17.9 36.5 40.9 17.2 30.2 7.6 31.1 18.8 25.3 27.1 12.3 32.9 15.6 14.4 27.3 25.6 28.0 6.5 37.1 38.5 44.0 27.6 18.5 15.7 14.4 19.3 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles NA NA Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favorable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 18.0 8.3 6.9 13.7 8.1 15.2 21.1 11.9 12.0 10.3 10.2 10.9 3.7 6.1 13.4 7.8 11.6 9.0 10.7 27.5 7.6 7.3 8.9 8.2 16.5 22.3 7.7 4.9 10.1 9.9 13.7 15.1 12.7 9.9 11.1 7.1 20.7 15.5 6.0 52.4 9.1 9.8 13.5 7.9 14.1 9.5 41.6 6.9 6.8 11.5 13.2 20.0 14.7 11.0 15.5 4.0 6.6 2.9 11.9 16.0 3.9 5.5 4.1 3.6 4.4 9.7 12.1 5.3 7.7 13.6 11.5 12.8 2.3 3.5 21.0 9.5 11.9 19.2 3.9 8.4 7.7 14.7 12.0 4.5 4.5 4.7 6.7 13.1 3.2 7.4 7.3 10.7 7.7 7.9 12.3 9.9 10.3 8.8 28.0 12.8 2.6 7.5 5.3 2.6 5.7 5.6 24.7 8.6 6.9 10.7 5.2 2.6 6.1 5.8 3.4 7.9 7.2 2.3 5.4 10.6 17.9 3.8 27.1 5.9 14.0 16.9 22.0 9.5 4.3 11.8 3.4 1.6 6.6 11.4 2.0 8.7 15.5 12.9 16.0 3.2 13.9 12.4 10.1 0.4 11.9 2.9 4.0 10.1 3.9 6.9 8.1 11.9 12.0 7.6 7.3 7.7 4.9 9.9 6.9 6.0 3.2 39.8 18.1 14.7 9.7 7.0 12.7 2.7 3.4 7.0 45.2 15.0 6.6 12.0 88.7 24.7 7.2 0.0 18.7 19.5 22.6 23.7 3.5 6.8 11.9 3.2 9.9 23.9 11.3 9.4 20.8 18.5 27.0 43.3 3.1 12.3 15.5 9.9 20.1 10.4 50.5 32.3 26.2 71.2 27.9 9.9 11.8 43.6 6.0 23.0 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.2" "Cell type enhanced" "Detected in all" 5 "Rod photoreceptor cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 6.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Approved "Plasma membrane,Cytosol" NA NA 43000 "Plasma membrane, Cytosol" "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 25.8 20.1 43.3 15.9 66.2 32.3 25.7 47.9 78.2 14.8 14.0 7.7 6.9 13.1 16.6 14.2 15.7 10.5 14.7 10.2 56.2 28.7 11.3 29.6 15.5 18.8 23.7 45.1 13.6 9.8 9.4 8.9 18.5 25.4 14.3 14.8 6.8 12.1 16.6 41.7 17.1 12.0 18.5 21.6 16.5 12.6 10.4 16.5 12.7 12.6 7.7 20.1 14.4 13.3 1.0 1.8 6.4 1.4 0.9 1.4 0.9 17.8 15.2 20.6 14.1 14.2 16.5 21.0 25.9 22.1 29.3 25.9 21.9 16.2 24.9 8.9 17.5 20.9 12.1 21.7 18.7 35.8 17.5 15.5 80.8 12.4 20.1 28.1 31.7 27.3 16.6 17.0 22.7 23.3 16.6 19.6 21.1 19.5 28.5 21.3 15.4 26.8 27.9 24.2 15.0 13.0 19.6 27.2 39.6 18.1 19.0 27.2 19.2 14.9 21.2 18.6 14.0 10.0 14.8 20.5 25.3 23.2 19.1 22.3 16.1 17.7 36.9 18.4 33.4 15.8 3.2 1.2 2.9 0.7 0.8 1.4 0.5 0.8 0.5 1.3 1.0 0.9 1.4 6.4 0.9 1.4 1.8 0.9 0.9 43.3 66.2 47.9 78.2 56.2 28.7 23.7 45.1 25.4 16.5 8.9 16.7 16.6 10.6 66.4 21.5 16.1 10.2 2.7 6.8 15.7 49.1 9.8 10.0 5.9 11.6 21.5 14.4 23.3 7.5 14.8 14.0 14.4 19.6 18.5 21.1 11.1 14.6 15.4 42.9 6.5 9.2 22.7 33.7 4.6 14.0 20.4 10.5 10.1 8.1 12.9 86.2 12.9 17.3 2.6 5.3 61.6 10.1 20.3 12.0 16.8 PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591615-101595021 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 90 "testis: 81.9" "Group enriched" "Detected in some" 25 "Early spermatids: 271.7;Late spermatids: 141.7;Spermatocytes: 319.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.3" "Low region specificity" "Detected in single" HPA047157 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA047157: AB_2679960" "unprognostic (8.81e-2)" "unprognostic (2.65e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 271.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 141.7 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 6.5 0.0 319.9 3.0 0.0 0.0 0.0 0.0 0.0 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085377 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 24.7 26.6 13.5 26.1 14.1 26.7 18.6 16.0 15.9 19.2 28.4 14.5 20.5 22.5 19.2 28.4 39.1 17.7 31.9 28.5 12.6 12.1 28.9 52.3 27.4 25.3 12.5 12.8 22.5 26.3 23.9 16.2 51.6 11.9 18.3 17.4 18.8 22.0 14.9 26.0 26.1 38.8 15.9 11.9 36.2 22.6 39.0 9.5 59.7 27.1 26.5 37.9 22.2 21.1 19.5 30.3 57.3 28.2 12.4 23.6 12.0 30.8 34.6 23.1 32.2 21.9 18.5 36.0 27.5 30.7 36.2 40.2 30.4 40.3 24.0 35.4 32.4 23.6 25.2 28.6 34.1 21.4 30.1 51.2 16.3 21.5 67.2 33.3 22.9 30.9 26.8 30.2 33.0 21.0 21.7 42.0 31.3 31.8 22.0 27.6 88.9 39.9 41.8 44.0 24.5 18.4 44.7 24.0 41.8 34.2 31.8 22.5 33.3 13.5 40.8 23.5 20.2 37.6 39.0 26.7 21.2 22.3 17.1 21.1 37.8 41.5 28.1 30.2 29.6 25.6 21.4 26.9 57.3 18.3 28.2 13.1 17.0 19.2 20.6 30.3 19.5 17.2 15.2 56.9 12.4 24.5 23.5 23.6 12.0 13.5 14.1 16.0 15.9 12.6 12.1 12.5 12.8 11.9 9.5 47.6 33.1 81.7 96.8 130.7 20.0 9.3 89.2 54.9 23.9 73.3 27.5 268.8 134.3 208.0 127.6 84.2 174.4 0.0 169.7 278.1 71.4 111.6 69.1 85.6 210.3 33.4 120.5 58.9 91.3 98.3 58.1 124.3 75.9 252.5 114.3 41.8 254.7 168.4 49.1 156.3 25.7 71.1 65.1 231.9 141.6 150.8 352.1 111.4 129.3 192.9 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46346994-46392981 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol NA NA 47000 "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: AB_2683278" "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 18.9 24.7 23.0 18.1 28.8 13.4 15.9 25.2 50.8 20.4 21.1 19.4 15.2 18.0 23.0 15.2 20.1 27.8 20.5 48.2 20.8 23.9 22.6 22.1 17.4 19.3 21.9 29.8 16.7 21.5 26.3 23.9 17.3 34.5 19.5 17.5 19.7 21.0 21.4 40.8 16.4 15.3 23.5 16.2 21.7 20.6 19.0 15.3 15.6 18.1 20.5 16.1 17.1 18.1 10.6 11.1 1.9 14.1 14.0 19.8 8.9 19.5 36.8 22.0 16.6 16.6 17.8 10.2 24.4 19.8 29.6 26.7 26.4 15.6 30.1 13.3 17.7 16.2 16.1 28.9 28.8 8.9 20.8 39.3 25.0 27.0 18.7 18.6 33.8 17.5 16.2 13.6 20.8 15.5 11.4 25.4 25.7 24.0 15.5 16.8 21.2 18.9 63.4 16.6 35.1 20.1 28.2 19.0 24.1 17.7 26.8 31.3 23.0 20.4 26.0 8.7 10.4 16.3 21.6 21.1 13.0 21.6 9.6 25.5 12.5 28.7 36.0 13.9 28.4 21.6 0.0 6.8 1.9 19.8 12.1 12.7 10.6 9.2 15.3 11.1 8.7 8.9 12.0 0.1 14.0 14.1 7.9 9.3 8.9 23.0 28.8 25.2 50.8 20.8 23.9 21.9 29.8 34.5 15.3 6.0 12.2 13.4 14.5 8.4 19.1 4.7 50.9 9.4 10.3 15.7 15.7 20.7 28.2 26.1 1.0 13.4 17.7 0.0 16.8 30.9 14.6 11.3 4.6 22.8 19.0 15.9 14.3 30.7 10.8 1.7 16.1 7.6 15.1 14.4 15.1 19.1 22.4 11.5 17.3 17.3 16.9 38.8 20.6 14.6 39.2 11.5 21.5 17.0 21.3 8.4 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain NA NA "HPA050940: AB_2681283" "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 21.7 20.1 20.1 15.7 24.5 24.8 21.2 20.8 26.2 17.0 19.1 25.9 15.1 13.9 15.6 17.2 21.2 14.0 12.9 15.3 19.8 16.6 22.8 17.8 16.3 21.5 20.1 16.1 17.5 27.7 21.3 17.3 17.6 17.8 14.5 21.8 16.8 26.9 14.6 50.5 19.3 17.3 16.3 22.6 19.4 16.5 22.8 23.7 34.1 22.2 20.5 24.0 13.8 15.6 17.3 14.8 32.2 19.5 13.9 23.3 13.8 14.1 10.3 18.8 17.8 20.2 16.9 19.0 15.0 16.3 22.2 18.6 16.5 15.0 20.4 11.7 20.1 18.9 28.9 25.4 16.3 25.8 18.2 12.3 16.7 16.2 14.6 16.6 29.1 23.2 13.9 22.4 18.2 17.4 17.1 20.7 23.4 19.5 23.7 23.9 21.0 27.4 18.4 17.5 39.6 19.2 22.4 28.5 27.2 18.8 14.3 19.5 19.3 26.8 21.6 17.4 16.7 33.4 18.4 20.0 13.7 13.1 26.5 19.9 26.2 47.2 27.0 18.4 19.1 22.2 27.2 13.2 21.4 14.7 17.4 18.0 17.3 18.9 16.6 14.8 13.3 18.9 17.5 32.2 13.9 19.5 10.7 23.3 13.8 20.1 24.5 20.8 26.2 19.8 16.6 20.1 16.1 17.8 23.7 38.7 27.8 41.7 45.6 68.7 15.2 30.8 35.7 21.4 23.9 26.2 7.9 40.2 48.0 40.6 102.7 41.4 34.6 23.3 47.6 45.3 30.1 41.0 43.9 36.1 46.7 14.3 46.0 46.6 52.3 56.7 27.6 48.9 42.2 46.9 41.6 28.7 41.6 38.6 33.9 54.9 12.9 51.8 44.8 93.3 43.0 76.5 72.9 49.0 37.9 48.2 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40071461-40097727 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease mutation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Hofbauer cells: 247.2;Kupffer cells: 246.8;Macrophages: 282.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 88.0;THP-1: 163.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 130000 "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 33.3 27.1 37.6 31.0 41.5 33.3 39.7 35.2 41.0 30.3 21.0 31.5 17.2 12.9 31.3 19.4 18.5 20.7 23.2 18.1 32.7 35.8 29.4 18.4 47.3 48.5 35.3 29.1 24.7 17.4 30.4 21.2 25.9 34.6 28.0 26.0 26.3 22.1 23.6 8.3 13.8 16.6 36.5 33.6 61.3 17.9 13.8 29.1 19.8 18.7 14.4 30.0 23.0 19.8 9.3 77.4 59.9 90.0 7.2 19.1 91.6 10.3 7.0 11.3 6.3 13.6 11.6 22.1 5.8 10.4 13.9 17.2 40.1 17.3 11.8 11.3 6.0 11.5 18.1 17.5 10.3 19.1 14.8 18.0 6.2 17.2 19.8 15.4 13.8 14.9 10.9 11.3 11.1 10.3 7.8 18.7 10.1 14.3 17.1 7.8 20.6 7.9 10.3 21.2 15.8 10.8 8.9 15.2 20.5 9.7 18.4 9.0 9.6 11.3 88.0 35.0 11.1 12.7 163.5 6.6 6.8 14.6 6.3 17.1 15.4 32.3 11.3 8.7 33.8 12.3 6.2 90.0 48.2 9.9 77.6 11.8 9.3 14.7 11.5 77.4 9.2 19.1 14.7 59.9 7.2 58.3 7.6 16.8 91.6 37.6 41.5 35.2 41.0 32.7 35.8 35.3 29.1 34.6 29.1 26.8 50.8 34.5 72.3 35.1 45.4 13.0 38.2 38.8 47.8 36.6 15.7 48.8 5.0 52.1 40.9 45.0 3.0 23.3 36.9 52.5 46.0 47.6 82.1 8.3 247.2 23.8 19.1 48.5 246.8 54.3 29.1 282.7 64.1 155.1 8.2 108.8 23.0 7.0 37.1 15.4 24.1 19.4 53.3 13.7 37.9 23.8 34.4 40.8 10.3 29.4 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163680 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 15.7;Syncytiotrophoblasts: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.0;EFO-21: 11.8;HEK 293: 20.4;MCF7: 8.7;RPTEC TERT1: 10.1;SK-MEL-30: 13.3;SuSa: 10.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 8.5 13.1 10.4 9.3 10.6 3.0 9.6 21.9 11.8 16.1 10.5 13.1 11.7 15.8 13.8 14.9 13.7 14.2 10.6 12.3 10.7 7.5 17.8 13.1 14.3 6.6 12.2 7.7 25.1 7.0 3.1 7.7 14.3 9.8 10.5 9.6 16.1 7.2 11.4 19.1 30.9 6.9 10.4 7.1 11.8 15.2 6.4 11.5 11.5 7.4 13.2 8.1 13.9 12.0 0.2 0.0 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 16.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.8 0.0 4.8 1.6 2.6 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.1 0.0 1.2 1.3 0.0 7.4 0.0 0.4 1.0 8.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.1 7.0 0.2 13.3 10.4 0.0 0.4 0.0 0.0 6.0 0.0 0.0 0.5 7.1 0.9 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.4 0.0 10.4 10.6 21.9 11.8 10.7 7.5 12.2 7.7 9.8 11.5 0.0 0.3 0.0 2.7 3.0 12.0 5.8 2.5 0.0 3.4 3.5 15.7 11.6 1.7 1.4 0.2 4.6 1.3 0.0 2.6 7.8 4.8 1.0 0.0 3.9 2.4 3.2 4.7 4.9 1.5 1.0 3.7 1.4 6.8 0.0 2.9 7.5 1.3 3.4 2.8 2.3 5.2 0.0 4.7 3.1 4.5 1.9 19.5 1.3 2.8 1.3 PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Early spermatids: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" NA NA "Nuclear bodies" "HPA019353: AB_1855668, HPA019360: AB_1855669" "unprognostic (3.31e-2)" "unprognostic (2.07e-2)" "unprognostic (6.78e-2)" "unprognostic (2.85e-1)" "unprognostic (9.61e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.37e-1)" "unprognostic (4.97e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-3)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.72e-4)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" 17.5 15.8 24.3 23.5 26.1 26.0 18.9 28.3 29.7 21.3 16.5 17.9 16.8 15.0 22.0 20.9 17.3 20.4 17.1 14.9 20.0 12.6 14.2 17.3 16.3 28.7 20.9 18.3 26.0 18.6 22.7 26.9 20.9 20.9 18.7 21.5 13.1 16.6 17.7 18.0 23.7 21.2 16.9 19.3 28.9 17.8 19.1 21.1 32.4 19.5 15.2 26.7 16.7 23.7 15.6 13.5 18.1 12.3 15.4 23.3 14.5 19.5 12.9 19.4 18.8 17.1 21.2 20.7 19.0 13.6 20.5 25.7 19.5 19.4 22.2 15.1 13.6 26.9 17.4 21.0 19.5 27.9 18.5 18.3 13.7 20.3 17.1 14.9 12.7 14.5 16.8 8.0 19.7 14.0 14.2 17.6 17.0 18.7 15.6 16.2 19.7 19.6 16.1 13.6 7.6 7.7 18.3 25.9 18.7 12.0 16.5 9.9 7.9 18.7 8.1 16.9 15.7 11.9 16.8 13.4 11.3 15.8 12.1 27.8 8.9 13.3 23.2 12.4 18.8 12.0 18.1 10.1 16.7 17.2 11.1 20.7 15.6 18.9 18.7 13.5 12.3 23.3 20.4 8.2 15.4 12.3 7.8 20.7 14.5 24.3 26.1 28.3 29.7 20.0 12.6 20.9 18.3 20.9 21.1 26.8 15.3 15.7 13.4 11.0 15.8 15.9 2.5 20.1 27.3 10.4 7.9 23.5 8.3 7.4 68.1 14.3 6.6 23.3 6.6 11.2 13.4 6.0 10.5 4.2 10.2 6.4 9.2 16.5 14.2 27.5 18.7 10.8 13.5 19.0 14.2 14.9 7.6 14.0 17.7 6.5 20.4 6.5 11.0 20.2 31.1 10.3 21.1 20.0 10.3 7.2 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105277565-105403084 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1400000 Cytosol "CAB025414: , HPA031388: AB_2673855, HPA031389: AB_2673856, HPA031390: AB_2673857" "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 13.0 14.2 10.1 22.2 10.1 10.4 36.2 10.9 24.9 11.9 27.2 5.2 11.2 20.2 13.2 10.9 16.4 10.5 15.0 19.0 8.8 7.1 8.9 14.6 23.9 31.4 8.3 15.4 13.6 18.8 16.1 11.1 15.4 9.7 9.4 33.0 8.9 14.9 11.5 58.0 24.2 19.0 15.3 8.5 11.9 14.0 20.1 8.8 17.4 10.2 18.5 13.3 18.2 21.0 8.3 15.3 7.1 18.7 16.6 16.3 11.2 11.0 13.5 14.5 16.2 34.3 20.3 14.3 14.9 14.0 19.7 20.9 17.2 7.0 14.2 14.7 17.5 18.2 17.2 21.3 43.6 22.4 21.4 20.8 19.0 11.4 19.6 13.2 19.2 13.9 18.8 26.6 14.1 36.5 14.9 18.3 25.1 32.4 25.4 23.8 18.0 12.8 19.5 14.0 21.4 13.6 19.8 24.9 9.2 14.7 26.4 19.0 27.1 13.1 21.9 10.4 19.2 9.4 30.8 18.4 9.0 12.6 11.3 18.3 7.4 4.9 18.6 16.0 20.9 28.1 4.8 13.6 7.1 16.0 15.4 15.6 8.3 13.7 16.3 15.3 6.8 12.9 15.2 0.7 16.6 18.7 6.5 12.0 11.2 10.1 10.1 10.9 24.9 8.8 7.1 8.3 15.4 9.7 8.8 3.0 7.0 6.1 5.7 9.6 5.3 13.2 5.1 1.4 7.9 7.0 13.7 16.0 5.0 9.1 0.9 9.0 15.7 0.0 10.2 27.4 9.0 4.3 13.8 13.9 13.4 12.7 18.6 9.2 15.8 2.4 10.0 10.0 5.0 18.0 33.1 3.3 12.9 17.3 8.5 6.7 9.5 0.0 12.3 2.1 17.9 7.4 56.8 11.3 34.9 7.6 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 230.0;Late spermatids: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB005050: AB_562037, HPA035409: AB_2674613, HPA064946: AB_2685390" "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.4 11.9 9.6 12.7 23.7 24.8 9.1 19.6 20.0 14.7 13.2 11.2 14.9 6.7 9.1 20.0 19.2 9.3 8.8 17.8 27.7 19.8 8.0 13.4 27.6 8.9 19.6 12.7 14.2 22.8 8.7 19.6 20.3 16.3 21.6 8.7 6.3 19.6 21.9 5.5 11.8 10.0 4.2 11.7 14.4 9.9 20.5 9.9 22.5 19.5 8.3 8.4 34.3 22.8 11.6 5.4 12.0 10.6 23.1 26.5 14.3 15.2 15.9 7.8 6.1 8.1 16.6 27.7 14.1 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 38.7 27.4 25.1 20.8 21.4 19.2 15.3 43.3 22.7 28.4 45.4 33.4 10.9 6.6 24.4 230.0 32.8 33.8 0.0 39.5 11.7 23.6 34.6 17.4 73.6 17.7 14.3 20.3 36.2 21.5 337.0 28.1 24.1 33.7 36.1 27.4 15.4 29.5 31.7 24.4 26.4 25.7 0.0 33.0 20.4 16.8 28.5 15.6 28.8 30.2 28.0 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell type enhanced" "Detected in many" 16 "Cardiomyocytes: 309.5;Rod photoreceptor cells: 106.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" NA NA "Nuclear speckles" "Golgi apparatus" "HPA044540: AB_2678977" "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favorable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.4 4.2 3.7 4.7 0.0 0.6 0.6 7.4 0.0 7.7 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 5.7 0.8 1.9 0.0 0.0 1.0 0.1 0.0 0.0 5.5 0.0 5.4 0.0 0.0 0.0 13.9 1.2 2.0 5.4 5.7 0.1 0.0 6.2 3.2 0.0 0.0 1.5 2.3 2.7 6.2 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 8.9 3.7 0.0 5.9 0.8 39.3 309.5 22.9 10.7 15.9 47.1 47.1 0.8 46.4 9.1 2.3 11.7 1.0 0.0 4.1 0.3 3.5 15.6 2.3 6.4 0.1 25.4 13.8 3.7 0.0 1.9 6.4 0.9 5.0 0.0 7.7 16.8 6.7 0.0 27.6 74.2 106.6 6.5 21.2 7.2 2.8 0.4 0.3 0.0 5.2 11.2 PRKAB2 ENSG00000131791 "Protein kinase AMP-activated non-catalytic subunit beta 2" O43741 1 147155106-147172550 "Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 52.1" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044342 Enhanced Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA044342: AB_10966508" "prognostic unfavorable (4.55e-4)" "unprognostic (2.03e-2)" "unprognostic (1.84e-1)" "unprognostic (4.03e-2)" "unprognostic (9.59e-3)" "prognostic unfavorable (7.32e-4)" "unprognostic (6.30e-2)" "unprognostic (1.23e-1)" "unprognostic (3.06e-2)" "unprognostic (6.78e-2)" "unprognostic (4.65e-2)" "unprognostic (1.98e-1)" "unprognostic (5.34e-2)" "unprognostic (1.31e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (6.78e-7)" "unprognostic (4.78e-2)" 7.7 7.6 5.6 4.6 7.1 4.7 7.6 13.3 10.9 9.3 24.6 8.9 8.9 19.1 13.0 8.1 10.0 7.4 6.5 15.2 5.6 5.2 6.2 32.6 6.3 3.8 5.9 9.3 8.1 21.0 18.4 6.2 7.5 7.8 10.9 6.9 6.3 5.7 12.6 52.1 9.4 19.1 20.5 8.4 5.7 11.1 6.9 5.5 2.6 5.8 19.9 4.7 19.0 10.3 1.2 1.7 2.9 1.6 5.1 2.5 0.8 3.9 2.2 5.9 4.5 14.0 12.1 21.3 7.5 4.1 5.0 5.5 8.8 7.9 7.2 3.8 5.9 2.9 10.6 6.8 8.4 4.9 2.8 4.7 3.2 7.0 14.2 9.6 3.7 1.4 9.5 16.9 5.2 24.7 7.5 4.9 5.6 4.4 2.9 4.3 4.0 2.7 2.1 12.3 6.8 9.8 4.3 7.9 3.5 3.6 3.2 3.8 7.1 5.6 6.4 26.7 22.0 6.0 4.6 5.6 5.7 12.6 5.2 12.1 4.7 5.1 3.7 5.9 3.3 7.4 2.9 1.2 1.9 1.5 1.2 2.5 1.2 1.6 0.9 1.7 1.1 1.7 1.1 0.3 5.1 1.6 0.8 0.7 0.8 5.6 7.1 13.3 10.9 5.6 5.2 5.9 9.3 7.8 5.5 3.0 1.3 5.0 9.8 14.7 13.2 57.1 25.5 4.0 2.3 17.4 13.7 15.9 1.7 5.0 0.4 6.7 25.7 0.0 6.0 30.8 10.6 4.3 1.1 35.0 5.1 11.1 10.9 6.7 7.3 1.1 8.9 4.1 15.1 9.0 10.7 6.6 7.4 10.1 15.2 4.7 18.6 19.4 21.1 12.4 9.4 12.3 17.2 7.5 8.8 3.9 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cardiomyocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" NA NA 1300000 Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 25.6 43.4 19.6 17.8 22.7 9.1 34.1 29.1 39.6 20.6 17.5 16.0 16.2 13.4 19.8 15.6 20.9 18.8 16.4 91.6 20.7 29.4 14.7 34.5 16.5 28.2 21.6 27.5 47.0 15.6 20.8 24.6 15.4 26.9 16.6 16.2 18.4 15.5 24.9 92.4 13.4 14.4 29.0 16.2 28.1 13.9 24.4 11.1 15.2 15.7 26.2 14.8 21.1 17.3 1.7 2.4 8.6 5.3 0.7 1.7 1.2 26.2 15.3 34.7 41.3 30.7 32.7 6.3 28.0 25.9 39.8 36.5 18.6 9.4 11.4 22.7 44.3 19.4 17.2 24.4 26.5 37.8 20.7 12.3 20.9 28.9 18.0 26.3 12.9 22.2 31.1 12.8 31.6 11.0 24.6 33.5 18.7 19.6 29.8 40.6 38.9 29.0 9.7 12.4 26.6 34.1 26.2 32.0 26.3 19.4 16.7 27.4 17.5 25.3 15.5 11.5 17.5 22.1 12.5 25.9 47.0 13.1 62.9 26.1 20.6 21.1 16.8 31.5 19.6 17.6 0.3 3.4 0.4 1.7 5.3 0.8 1.7 0.9 1.1 2.4 1.3 1.2 1.7 8.6 0.7 4.6 1.6 0.8 1.2 19.6 22.7 29.1 39.6 20.7 29.4 21.6 27.5 26.9 11.1 6.0 4.3 11.5 6.1 7.8 40.4 110.4 28.1 4.0 2.3 14.0 25.5 5.8 6.6 10.7 25.7 21.6 16.0 0.0 16.2 4.8 14.3 7.3 0.0 30.1 29.0 3.2 16.8 31.9 44.8 12.8 45.5 32.4 13.5 7.2 14.3 24.1 13.5 7.0 48.8 9.6 23.0 19.4 17.3 25.7 6.4 9.8 6.8 7.2 11.4 6.4 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 85.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" NA NA 1500000 Cytosol "Cytokinetic bridge" "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: AB_2686356" "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favorable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 7.0 21.5 40.0 10.5 57.0 6.2 8.0 54.7 85.5 9.4 23.6 16.9 3.9 4.8 8.7 17.6 8.1 5.2 11.5 10.1 43.1 52.1 10.6 9.0 6.9 16.2 38.3 33.5 8.3 11.9 12.2 18.3 5.1 35.5 13.8 22.6 4.9 32.9 12.7 3.2 2.6 6.3 12.6 47.7 14.6 14.2 3.6 25.9 25.5 11.1 1.8 15.3 13.5 4.6 13.5 7.1 17.1 5.4 25.9 27.6 22.0 3.1 6.3 10.1 12.1 11.7 10.3 4.7 15.6 11.9 8.0 7.5 0.1 2.8 16.6 10.8 12.2 14.6 2.2 4.7 5.1 8.5 16.1 2.6 36.5 8.6 1.2 11.5 14.4 0.8 6.1 2.3 7.7 4.3 11.6 36.6 6.2 1.1 9.6 12.9 0.6 18.7 7.6 9.9 0.0 4.4 14.5 15.7 10.0 19.4 11.2 3.3 12.9 8.6 3.3 9.5 7.9 3.0 3.0 32.4 11.1 8.6 11.2 11.8 7.1 8.5 16.7 5.3 15.4 13.8 17.1 2.7 5.8 23.3 3.6 18.7 13.5 17.3 20.6 7.1 10.2 26.4 27.6 1.5 25.9 5.4 4.1 15.9 22.0 40.0 57.0 54.7 58.2 43.1 52.1 38.3 33.5 35.5 25.9 0.0 1.0 20.3 6.7 4.5 44.0 38.9 15.3 4.0 5.7 14.0 33.4 1.4 28.2 6.9 2.4 8.4 61.7 0.0 10.3 1.0 11.0 15.2 57.7 14.8 23.2 44.5 20.8 26.4 52.7 2.6 13.8 32.7 15.1 1.0 61.1 36.9 13.3 28.8 20.5 15.6 30.0 12.9 13.7 5.9 6.9 2.5 0.6 69.2 52.4 6.5 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012529-69014113 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 27.4" "Group enriched" "Detected in some" 8 "Early spermatids: 55.1;Late spermatids: 73.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 1.3" "CAB004530, HPA071185" Supported Uncertain "Cytokinetic bridge,Cytosol" NA NA Cytosol "Cytokinetic bridge" "CAB004530: AB_628137, HPA071185: AB_2686356" "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 1.5 0.0 0.0 0.0 0.0 0.0 PRKAG2 "AAKG, AAKG2, CMH6, H91620p, WPWS" ENSG00000106617 "Protein kinase AMP-activated non-catalytic subunit gamma 2" Q9UGJ0 7 151556111-151877125 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Cardiomyopathy, Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 77.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 58.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004246, CAB018641" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "CAB018641: AB_2170355, HPA004246: AB_1078151" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.46e-2)" "unprognostic (9.29e-2)" "unprognostic (1.76e-1)" "unprognostic (4.33e-3)" "unprognostic (7.13e-2)" "unprognostic (8.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.80e-1)" "unprognostic (3.61e-2)" "unprognostic (4.52e-1)" 12.8 5.5 15.3 8.7 28.8 6.3 9.7 31.1 19.2 8.8 11.5 7.5 9.4 16.7 10.4 10.9 10.8 8.6 12.0 77.2 15.1 13.5 15.4 18.5 8.6 7.7 12.3 14.3 6.8 6.2 6.7 5.1 20.0 18.3 17.5 13.5 7.8 11.9 14.8 21.5 6.9 17.8 32.8 8.5 12.8 13.8 9.7 9.5 2.3 12.6 5.2 7.1 22.4 12.4 7.9 7.8 18.4 6.0 3.1 6.1 3.5 15.5 4.5 3.0 3.6 13.9 11.8 5.4 7.1 6.4 7.7 7.6 2.9 19.9 0.0 11.8 9.5 58.6 5.0 1.9 8.3 12.5 3.7 2.1 4.1 0.5 0.3 20.7 3.1 4.0 5.7 17.8 7.7 8.2 12.8 13.2 4.7 1.4 1.9 23.3 5.8 1.6 2.2 3.1 6.8 13.2 1.5 2.2 3.2 14.7 3.7 13.7 2.1 4.2 7.8 3.1 8.3 2.5 4.1 17.6 1.8 1.5 0.9 4.5 1.4 1.6 0.0 21.9 9.6 17.3 18.4 6.0 10.5 5.1 5.4 3.7 7.9 4.5 4.5 4.3 3.8 4.2 6.1 13.6 3.1 5.4 7.8 2.4 3.5 15.3 28.8 31.1 19.2 15.1 13.5 12.3 14.3 18.3 9.5 6.0 17.5 17.5 32.5 9.4 15.4 84.3 7.6 14.7 13.6 43.6 7.9 2.9 54.7 13.4 39.3 19.4 29.8 0.0 19.9 19.0 16.6 41.6 21.9 55.7 17.5 3.2 12.6 19.6 50.9 26.6 6.9 39.9 15.1 42.3 27.6 18.6 19.6 17.5 7.4 14.7 4.4 12.9 29.1 3.5 19.8 9.5 42.3 26.1 25.4 38.3 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Cardiomyocytes: 608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 11000000 Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 47.1 48.0 41.7 34.5 54.8 14.6 38.7 40.4 57.4 48.2 23.8 44.9 31.4 15.1 43.6 37.7 29.6 43.2 37.4 122.7 42.5 52.3 49.2 43.4 47.3 29.5 50.1 43.6 62.5 19.1 107.8 41.9 47.3 57.7 35.6 24.2 32.2 47.5 43.6 99.8 22.8 19.3 39.4 52.8 35.3 25.1 36.9 40.1 28.2 51.8 23.6 29.2 33.8 33.4 11.3 26.9 52.6 28.7 18.5 13.0 22.9 16.6 32.1 41.2 24.6 55.0 62.5 6.2 22.5 46.5 35.2 31.2 12.5 22.5 16.9 15.5 49.1 36.1 13.8 30.4 36.5 50.6 11.4 10.9 26.2 27.9 40.8 39.9 20.0 29.4 44.6 38.0 40.6 34.3 39.6 58.4 14.5 11.8 26.7 42.6 31.6 22.0 10.7 15.2 17.2 21.9 15.4 68.2 18.7 53.4 36.3 15.0 20.3 20.6 37.7 86.7 40.0 29.5 28.3 41.4 49.7 23.7 22.4 20.9 22.3 15.8 25.2 30.1 19.1 30.9 31.1 26.1 46.3 13.0 25.5 13.0 11.3 9.8 11.6 26.9 8.5 8.9 9.8 52.6 18.5 28.7 8.8 12.3 22.9 41.7 54.8 40.4 57.4 42.5 52.3 50.1 43.6 57.7 40.1 137.0 210.8 75.1 77.8 126.8 93.4 608.0 89.2 258.3 168.4 239.0 62.8 66.4 150.9 74.2 287.1 138.4 34.9 23.3 45.5 74.3 135.4 82.7 180.2 101.7 123.8 131.9 131.3 160.2 157.1 53.4 123.7 102.2 182.2 93.8 51.5 115.8 62.1 52.9 179.3 150.9 56.6 84.1 208.1 100.7 40.5 115.2 69.0 106.6 36.6 95.0 PRKAR1B ENSG00000188191 "Protein kinase cAMP-dependent type I regulatory subunit beta" P31321 7 549197-727650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 83.6" "Cell type enhanced" "Detected in many" 10 "Early spermatids: 48.9;Horizontal cells: 50.9;Late spermatids: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 41.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026719 Approved NA NA "HPA026719: AB_1855419" "unprognostic (4.90e-2)" "unprognostic (4.92e-2)" "unprognostic (2.69e-1)" "unprognostic (4.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.02e-3)" "unprognostic (3.28e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-1)" "unprognostic (1.41e-2)" "unprognostic (2.01e-3)" "unprognostic (1.95e-1)" "unprognostic (3.38e-3)" "unprognostic (5.18e-2)" "unprognostic (2.64e-1)" "unprognostic (9.23e-2)" "unprognostic (2.00e-1)" 5.0 6.8 33.6 4.3 30.4 4.5 4.0 24.0 83.6 4.8 5.7 3.4 1.6 7.2 7.2 2.7 4.2 6.2 4.6 7.7 35.5 42.8 5.4 3.8 5.5 5.2 22.5 29.2 12.9 4.1 5.6 7.0 3.5 29.7 6.0 4.2 2.5 3.9 5.5 3.8 3.0 7.6 5.3 9.1 8.2 3.8 4.8 3.7 2.5 2.9 1.4 3.3 3.5 2.6 7.0 5.5 1.5 2.6 3.5 12.8 10.3 25.3 17.5 2.6 6.4 1.7 1.5 7.4 5.1 2.4 3.3 1.9 31.3 5.6 19.2 3.5 2.3 10.9 18.7 8.7 9.7 1.4 4.0 6.3 1.3 11.3 20.6 3.2 12.1 3.1 4.3 3.0 2.1 6.2 3.6 3.5 5.1 18.4 3.9 2.9 24.3 14.7 8.0 41.0 7.0 6.9 9.5 0.5 8.5 8.2 6.7 34.4 25.9 13.0 12.8 10.0 1.1 6.6 4.6 4.2 1.5 3.2 1.9 10.3 2.4 6.9 12.5 2.7 9.4 19.1 1.5 2.0 0.0 4.6 2.6 6.9 6.2 7.9 7.1 2.4 7.0 12.8 11.7 0.8 3.5 0.9 5.5 5.2 10.3 33.6 30.4 24.0 68.6 35.5 42.8 22.5 29.2 29.7 3.7 3.0 4.1 8.2 6.8 3.4 9.4 11.5 0.0 0.0 5.7 5.2 3.9 3.1 21.6 4.0 48.9 11.3 13.8 0.0 3.0 5.1 4.7 4.5 6.9 7.4 9.0 50.9 4.1 16.0 3.3 101.7 10.9 2.3 6.8 1.0 10.6 5.1 6.7 12.9 14.5 15.3 4.4 0.0 5.0 9.5 8.5 4.1 2.9 8.7 13.8 4.1 PRKAR2A PRKAR2 ENSG00000114302 "Protein kinase cAMP-dependent type II regulatory subunit alpha" P13861 3 48744597-48847846 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Group enriched" "Detected in many" 8 "Early spermatids: 709.6;Late spermatids: 1080.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005023, HPA038268" Uncertain NA NA 350000 "CAB005023: AB_562330, HPA038268: AB_2675921" "unprognostic (2.81e-2)" "unprognostic (3.59e-1)" "prognostic favorable (4.27e-5)" "unprognostic (1.60e-1)" "unprognostic (4.01e-2)" "unprognostic (6.17e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (4.77e-2)" "unprognostic (2.65e-1)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (9.18e-2)" "prognostic favorable (2.07e-4)" "unprognostic (3.59e-2)" "unprognostic (3.54e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-2)" 14.4 14.0 7.7 8.2 7.9 10.0 8.7 8.3 9.1 11.0 13.9 9.7 12.7 7.9 10.5 9.6 13.7 11.2 10.6 16.8 6.5 8.4 13.2 20.1 8.1 7.2 7.7 7.9 13.2 9.2 11.6 6.9 7.0 7.9 10.6 12.4 11.3 14.3 13.5 47.7 9.5 12.6 10.6 6.9 8.3 9.7 58.4 6.1 3.2 11.0 14.2 10.6 13.3 13.9 8.1 8.7 13.3 14.6 9.7 10.1 6.7 17.2 11.6 9.7 7.5 14.7 14.9 11.0 19.8 9.9 17.4 11.1 15.3 7.8 15.2 13.9 20.5 11.3 7.9 27.7 17.4 23.6 12.4 10.3 20.2 21.2 11.3 10.8 21.1 13.1 12.4 13.7 22.4 16.5 6.5 18.3 5.2 22.7 9.8 16.4 6.7 0.1 6.9 6.9 12.7 13.0 6.4 12.4 19.2 11.2 19.0 9.7 10.0 19.5 23.4 13.1 11.0 15.7 16.5 23.1 15.4 12.3 24.9 27.2 16.7 32.0 14.7 20.7 23.5 11.6 10.9 9.1 10.5 10.1 8.1 9.7 8.1 8.5 8.6 8.7 7.6 6.1 6.0 13.3 9.7 14.6 5.4 7.4 6.7 7.7 7.9 8.3 9.1 6.5 8.4 7.7 7.9 7.9 6.1 17.9 57.6 32.6 21.1 37.3 43.0 58.5 48.4 37.5 29.6 43.6 64.8 20.5 18.3 35.9 709.6 35.8 55.1 0.0 52.6 28.9 32.5 32.7 12.7 106.1 42.1 58.8 40.4 56.4 50.0 1080.4 50.9 37.1 28.7 25.2 39.0 26.1 51.6 31.6 52.3 35.6 43.2 51.8 53.8 64.4 59.7 54.8 19.7 27.4 66.4 22.6 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044649-107161811 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "adipose tissue: 80.2;breast: 114.1" "Cell type enhanced" "Detected in many" 7 "Peritubular cells: 49.8;Smooth muscle cells: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "myeloid DC: 3.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 20.1;Daudi: 27.6;K-562: 16.6;U-698: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria NA NA 1600000 Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" 80.2 21.5 9.4 6.0 17.2 8.4 114.1 4.5 17.0 3.9 9.1 1.9 2.4 3.1 5.1 3.9 8.4 3.4 4.7 9.0 8.8 8.6 4.5 2.4 3.2 3.0 8.4 12.1 19.5 6.5 5.6 8.1 10.7 3.0 6.4 5.5 2.6 6.8 3.9 2.2 1.6 4.7 7.4 3.4 11.1 4.1 14.5 4.6 0.8 1.6 2.8 3.3 8.4 11.8 0.2 3.1 1.3 1.5 0.5 0.1 2.5 0.0 0.4 2.6 20.1 10.8 0.0 0.0 1.0 3.2 0.8 0.8 0.0 0.0 27.6 0.2 0.6 2.5 0.0 2.0 0.0 1.6 0.7 2.2 9.2 0.0 0.0 3.0 0.1 1.3 0.1 0.0 0.0 0.0 0.9 12.1 1.5 16.6 0.8 0.0 2.0 3.7 0.1 4.9 0.0 0.8 1.1 0.0 0.0 0.0 0.0 3.3 4.8 1.5 0.3 1.0 6.9 0.6 1.9 6.8 1.0 2.6 0.0 1.9 0.6 0.0 71.0 0.7 4.8 9.6 1.3 1.5 0.0 0.0 1.4 0.1 0.2 0.0 0.0 3.1 0.0 0.1 0.1 0.7 0.5 0.7 1.1 0.0 2.5 9.4 17.2 4.5 17.0 8.8 8.6 8.4 12.1 3.0 4.6 3.0 1.0 0.8 1.4 2.2 29.0 26.0 10.2 6.7 1.2 7.0 9.8 0.0 0.0 1.7 6.2 15.5 0.0 0.0 0.0 0.4 5.1 5.9 4.6 0.0 1.5 4.8 0.0 14.1 14.0 4.7 27.6 10.4 16.9 13.6 0.5 5.5 0.2 2.6 49.8 0.6 9.1 19.4 35.8 1.6 4.5 2.0 0.0 2.9 1.9 3.9 PRKCA PKCA ENSG00000154229 "Protein kinase C alpha" P17252 17 66302636-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Rod photoreceptor cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "dendritic cells: 1.4;monocytes: 2.7;T-cells: 4.0" "Cell line enhanced" "Detected in many" "U-87 MG: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" NA NA 1900000 Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 4.0 19.6 26.5 9.0 22.8 2.5 3.0 10.8 33.9 7.0 13.8 19.0 3.5 14.6 14.8 6.7 4.7 6.1 10.8 5.8 31.6 15.6 16.7 6.5 6.0 8.4 18.7 15.6 20.4 5.5 1.7 6.0 6.5 17.6 17.2 11.2 7.0 3.1 22.3 6.6 3.8 12.7 13.7 15.0 7.9 7.9 3.7 14.4 0.4 4.5 1.3 5.9 9.5 9.5 0.0 1.4 0.1 2.7 0.1 4.0 1.0 2.3 12.5 2.6 2.6 6.3 16.1 0.3 13.4 8.8 9.7 8.3 1.4 1.5 3.1 3.6 21.7 16.3 0.3 1.3 1.6 21.2 5.2 3.0 0.0 7.4 6.5 8.6 3.9 21.1 7.0 0.6 12.1 10.4 14.2 8.3 15.1 8.1 0.0 15.0 0.7 7.8 2.4 1.0 6.1 6.7 1.4 19.1 0.0 3.4 2.1 1.5 8.6 4.4 2.6 0.1 2.8 0.3 5.5 24.8 16.9 9.8 10.5 8.4 0.0 0.0 0.3 53.7 0.0 8.3 0.1 0.6 0.0 0.5 0.8 1.5 0.0 2.5 1.2 1.1 0.0 4.0 2.3 0.0 0.1 2.7 1.4 0.5 1.0 26.5 22.8 10.8 28.2 31.6 15.6 18.7 15.6 17.6 14.4 0.0 9.6 3.9 15.4 9.4 33.9 7.9 40.8 5.3 4.5 38.4 2.0 3.3 6.6 11.3 2.5 3.0 24.2 0.0 5.9 2.8 11.0 12.4 20.7 11.9 19.7 9.5 8.1 36.8 8.2 1.3 49.5 7.7 10.1 1.8 32.8 43.1 7.2 20.1 45.6 16.8 77.1 25.8 17.0 1.1 1.7 9.2 12.7 24.1 21.3 12.3 PRKCB "PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835946-24220611 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.2;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" 11 "B-cells: 149.8;Bipolar cells: 172.0;Horizontal cells: 74.7;Kupffer cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 41.7;HMC-1: 41.8;K-562: 59.4;THP-1: 18.8;U-937: 16.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 3400000 Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.0 1.9 13.9 20.8 55.6 20.4 1.8 14.1 57.2 4.1 4.7 4.4 0.6 4.9 3.5 1.2 3.2 2.6 3.9 1.5 23.4 7.8 1.8 3.7 5.4 31.0 11.0 20.4 1.2 1.4 0.9 1.4 2.5 8.3 6.2 4.4 3.5 1.9 8.4 1.2 4.6 9.1 5.8 7.3 31.2 3.8 6.4 6.4 24.1 3.9 0.0 27.7 7.6 1.7 23.6 18.5 21.8 14.6 20.1 19.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 41.7 2.0 0.0 0.0 6.0 41.8 0.0 0.2 0.0 0.0 0.0 0.0 7.2 59.4 0.1 0.0 0.0 13.1 13.2 0.4 0.0 0.0 12.5 0.1 2.4 0.1 3.6 7.3 0.0 0.0 0.0 0.6 0.2 0.0 18.8 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 16.8 0.0 17.5 7.6 14.4 14.5 10.7 6.7 23.6 9.5 17.2 6.2 22.1 7.8 19.0 21.8 20.1 14.6 18.5 6.7 7.5 13.9 55.6 14.1 57.2 23.4 7.8 11.0 20.4 8.3 6.4 3.0 8.2 149.8 3.5 5.4 172.0 1.7 5.1 2.7 1.2 1.8 2.0 0.1 0.0 0.0 16.3 1.4 1.7 0.0 0.2 0.2 1.3 0.7 69.4 1.6 41.0 74.7 0.0 16.5 192.8 10.0 0.0 22.7 3.3 6.4 0.7 9.9 0.0 9.5 0.4 0.1 7.3 0.0 2.2 3.6 3.7 12.5 0.7 57.5 1.2 4.3 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Cell line enhanced" "Detected in all" "SK-BR-3: 64.7;THP-1: 46.1" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.9 3.0 1.2 2.1 9.2 5.3 11.4 4.8 6.1 5.9 5.8 7.4 7.8 20.4 2.1 10.4 10.3 3.6 8.1 11.8 4.9 17.8 6.1 11.3 4.2 7.9 5.9 14.9 25.7 4.1 8.6 6.1 5.6 5.3 5.1 2.2 2.2 2.9 8.5 19.5 1.6 25.5 3.2 11.9 5.6 1.7 3.1 4.9 6.4 17.0 2.0 1.4 3.6 64.7 9.9 6.3 5.4 46.1 7.4 2.9 3.6 3.8 4.5 4.5 6.9 10.5 6.8 25.8 5.5 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 3.0 19.7 17.6 21.2 26.0 0.0 4.5 12.7 16.0 17.0 14.0 0.0 2.5 3.3 7.6 26.7 1.8 56.8 0.0 9.6 13.5 8.7 14.8 5.7 1.7 38.4 1.6 25.5 3.7 43.0 59.4 8.3 35.2 10.1 21.6 29.0 1.8 10.3 49.1 6.3 10.9 0.0 6.5 9.4 5.2 1.9 24.3 7.3 7.5 20.6 28.8 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Group enriched" "Detected in many" 5 "Early spermatids: 209.3;Late spermatids: 297.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 19.4;TIME: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 5.5 7.4 15.3 7.2 14.2 9.3 8.1 28.8 36.5 6.6 5.5 3.8 5.9 3.6 5.6 4.6 4.7 7.6 4.7 7.7 22.5 10.0 12.8 15.5 17.5 6.9 6.0 15.0 4.1 4.2 16.3 6.0 10.4 9.1 3.6 4.7 3.7 3.6 8.6 7.2 3.0 3.7 6.2 4.4 4.9 4.4 7.2 3.7 1.5 6.5 1.2 5.4 5.0 6.5 5.5 2.2 1.7 1.4 0.9 1.3 0.6 5.4 2.0 2.9 2.9 4.4 5.2 2.3 3.8 7.0 3.2 3.5 0.5 5.4 8.2 3.6 4.0 4.6 1.3 1.8 2.0 4.6 4.9 3.5 0.0 1.4 1.1 5.0 0.6 2.9 4.6 2.3 4.8 3.5 2.7 11.8 1.8 1.1 2.0 3.7 2.8 2.6 0.3 1.0 3.0 1.0 19.4 13.8 8.8 2.9 3.7 2.0 4.4 1.7 5.8 12.5 1.1 4.7 1.9 19.5 6.3 6.6 4.6 3.8 0.0 0.0 6.9 5.2 4.6 6.3 0.0 1.2 1.7 1.0 0.4 1.1 3.6 0.7 0.7 2.2 5.5 1.3 0.4 0.4 0.9 1.4 0.9 0.0 0.6 15.3 14.2 28.8 33.2 22.5 10.0 6.0 15.0 9.1 3.7 6.0 8.6 20.1 6.3 4.4 47.5 9.3 12.7 22.7 27.3 10.4 13.7 0.3 3.3 3.0 209.3 9.9 4.5 0.0 3.3 6.9 8.0 5.7 6.9 7.3 2.6 11.1 7.5 12.3 17.0 297.3 4.9 11.1 13.5 7.2 5.3 7.0 3.0 3.5 5.6 21.3 6.7 12.9 6.6 2.7 2.2 4.3 2.4 4.3 6.2 7.1 PRKCG "MGC57564, PKCC, PKCG, SCA14" ENSG00000126583 "Protein kinase C gamma" P05129 19 53879190-53907652 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 49.9" "Cell type enhanced" "Detected in some" 15 "Early spermatids: 3.7;Horizontal cells: 4.8;Spermatocytes: 2.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.8;OE19: 8.5;SH-SY5Y: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054560 Enhanced NA NA "HPA054560: AB_2682523" "unprognostic (7.14e-2)" "unprognostic (5.42e-2)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.09e-1)" "unprognostic (2.64e-2)" "unprognostic (7.48e-3)" "unprognostic (2.68e-1)" "unprognostic (2.22e-7)" "unprognostic (2.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" 1.0 0.9 28.0 1.1 49.9 2.2 0.9 12.1 39.2 0.9 1.3 1.6 0.0 1.5 1.0 0.9 1.0 1.4 1.0 0.9 49.7 4.4 0.9 0.9 1.0 0.9 2.9 20.8 0.9 3.5 2.1 0.2 0.9 0.7 0.9 1.2 0.0 0.9 1.0 1.0 0.9 1.3 1.1 1.4 0.9 1.8 4.4 2.1 1.3 0.9 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 4.8 1.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 1.2 1.3 0.2 1.4 0.0 0.5 0.4 2.3 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.5 0.0 0.9 0.0 1.2 0.0 0.1 0.0 0.5 0.4 0.1 0.8 8.5 0.4 0.8 0.5 0.0 0.9 0.0 0.0 3.3 1.3 0.1 0.0 1.7 1.6 0.0 0.8 0.0 1.6 0.0 0.0 1.4 0.3 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 49.9 12.1 28.5 49.7 4.4 2.9 20.8 0.7 2.1 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.0 0.0 0.0 0.0 0.2 0.1 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Endothelial cells: 56.0;Erythroid cells: 70.0;Ito cells: 55.9;T-cells: 137.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "gdT-cell: 30.0;MAIT T-cell: 23.9;memory CD4 T-cell: 23.0;memory CD8 T-cell: 35.3;naive CD4 T-cell: 28.5;naive CD8 T-cell: 27.6;NK-cell: 27.3;T-reg: 18.6" "Group enriched" "Detected in many" 14 "NK-cells: 27.3;T-cells: 35.3" "Cell line enhanced" "Detected in many" "BEWO: 30.4;HUVEC TERT2: 39.9;MOLT-4: 26.5;RT4: 16.8;TIME: 26.1" "Group enriched" "Detected in many" 6 "basal ganglia: 25.0;thalamus: 19.5" "Low region specificity" "Detected in many" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 17.5 5.4 5.0 21.6 22.0 11.2 14.7 2.8 6.1 13.6 10.3 6.2 6.9 5.1 19.1 7.0 20.1 8.6 12.7 10.1 6.8 4.4 8.1 5.5 24.1 27.6 5.9 2.5 7.1 5.9 8.8 15.5 22.7 7.2 9.8 5.0 9.1 24.7 10.8 9.1 15.9 16.0 10.5 5.7 25.9 6.0 4.3 6.4 54.6 15.1 10.6 34.6 13.2 14.4 0.4 2.2 1.5 0.7 27.3 35.3 17.9 6.4 2.2 0.3 1.7 1.0 0.2 30.4 0.1 0.5 0.3 0.3 0.7 3.8 0.1 4.6 0.0 0.6 4.4 0.2 4.9 0.5 0.8 2.9 0.0 0.7 0.2 0.4 0.0 0.9 0.8 5.1 0.2 3.5 0.4 39.9 12.9 0.0 0.1 2.3 11.7 26.5 0.2 0.5 4.6 3.1 2.2 1.1 0.0 0.0 16.8 1.1 1.9 0.7 5.9 3.6 5.6 5.8 0.5 26.1 0.7 5.2 0.8 0.3 0.5 0.1 0.2 1.1 0.4 1.3 0.1 0.7 0.5 30.0 0.4 23.9 0.4 23.0 35.3 2.2 0.3 28.5 27.6 1.5 27.3 0.2 0.7 18.6 17.9 5.0 22.0 2.8 6.1 6.8 4.4 5.9 2.5 7.2 6.4 6.0 10.7 4.6 15.8 16.7 0.2 3.9 10.2 10.7 18.2 0.0 0.0 23.4 3.3 4.6 25.5 56.0 1.7 70.0 5.9 16.9 3.7 13.1 1.1 1.0 5.6 0.0 11.3 55.9 11.1 3.6 1.7 9.0 15.1 5.4 2.6 9.3 4.4 2.9 6.3 0.8 0.3 0.0 4.1 0.0 2.1 23.3 40.4 137.1 0.7 24.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222365-170305981 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: AB_2676124" "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favorable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 10.3 7.5 11.4 5.9 15.5 2.1 9.5 14.8 16.6 12.5 11.1 7.0 6.0 10.4 13.1 8.4 20.6 15.1 10.5 10.1 9.5 7.7 13.0 6.7 14.8 3.9 5.6 9.4 15.2 7.7 12.4 14.7 9.8 11.0 16.3 12.2 7.3 25.8 12.6 12.7 11.0 11.6 12.5 6.8 6.1 30.2 15.0 5.3 12.6 23.1 8.4 9.9 16.3 13.0 1.9 1.8 1.0 1.3 5.8 4.8 1.4 34.3 8.7 8.8 9.4 7.8 10.9 14.2 8.8 13.0 11.7 12.7 12.7 16.8 10.5 29.1 12.3 16.1 16.1 16.5 17.3 20.1 7.6 10.2 9.7 11.0 7.0 12.4 8.7 4.4 9.8 12.1 10.0 15.7 19.0 9.1 5.8 10.7 8.7 11.7 11.8 12.6 3.4 18.4 36.7 9.7 9.2 13.5 17.3 18.4 10.5 14.0 11.4 19.0 25.0 8.6 13.6 27.5 6.0 9.6 12.2 9.4 11.4 14.5 15.0 14.4 15.0 8.8 6.9 4.7 0.1 1.3 1.0 2.6 1.2 4.0 1.8 3.6 4.8 1.8 1.9 3.9 2.2 0.7 5.8 1.1 1.8 2.3 1.4 11.4 15.5 14.8 16.6 9.5 7.7 5.6 9.4 11.0 5.3 68.5 56.0 2.2 46.0 50.7 15.9 14.9 25.5 22.7 46.6 47.1 13.7 23.8 21.6 13.9 5.5 18.0 21.2 0.0 19.5 22.1 25.6 78.7 8.1 17.8 8.9 14.3 28.2 16.5 20.8 3.6 21.6 10.0 16.9 6.4 28.1 8.1 36.5 17.5 26.9 15.1 9.3 19.4 11.4 12.9 15.1 55.7 17.3 5.7 27.7 69.1 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 19.7;lymphoid tissue: 32.1;skeletal muscle: 63.4" "Cell type enhanced" "Detected in many" 19 "Alveolar cells type 2: 6.5;Distal tubular cells: 6.6;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 12.7;MAIT T-cell: 9.8;memory CD4 T-cell: 13.5;memory CD8 T-cell: 13.2;naive CD4 T-cell: 10.7;naive CD8 T-cell: 10.0;NK-cell: 6.5;T-reg: 19.7" "Group enriched" "Detected in many" 11 "NK-cells: 6.5;T-cells: 19.7" "Cell line enhanced" "Detected in some" "HEL: 29.8;JURKAT: 21.2;MOLT-4: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA 200000 "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.9 0.7 3.6 9.4 4.3 3.1 0.8 0.9 5.2 1.3 1.1 7.4 0.1 1.2 1.8 5.4 1.6 2.6 1.3 0.5 4.4 4.0 4.6 0.9 3.3 6.6 4.0 2.2 1.1 7.7 0.3 1.0 0.4 2.7 1.4 1.3 5.4 2.8 1.0 63.4 0.6 2.5 0.8 3.6 3.4 1.4 0.9 4.5 32.1 9.1 7.5 6.8 1.9 0.8 0.0 0.1 1.1 0.2 6.5 19.7 5.2 0.0 2.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.2 1.8 0.2 0.0 0.0 0.0 0.0 1.8 3.1 0.0 0.0 2.0 29.8 0.0 0.2 0.3 1.4 0.3 0.1 1.9 0.1 0.1 0.0 0.2 21.2 6.5 0.0 0.0 0.0 22.3 4.2 3.1 0.2 0.0 4.3 0.7 0.0 6.3 1.5 0.2 1.1 0.0 0.0 0.0 1.9 0.0 3.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 1.1 0.1 0.1 12.7 0.2 9.8 0.0 13.5 13.2 0.1 0.0 10.7 10.0 0.8 6.5 0.0 0.0 19.7 5.2 3.6 4.3 0.9 5.2 4.4 4.0 4.0 2.2 2.7 4.5 3.0 6.5 0.0 0.1 0.0 1.6 0.3 0.0 1.4 1.2 1.8 0.0 0.0 6.6 0.2 1.8 0.0 0.0 0.0 0.7 0.1 0.3 0.0 1.1 0.0 0.4 0.0 1.7 1.3 1.5 4.5 0.0 0.5 0.0 0.0 0.3 1.5 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.9 2.0 0.0 0.0 25.4 0.3 0.1 PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435288-11450968 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 62000000 "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: AB_2677758, HPA043560: AB_2678553" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" 46.9 37.4 26.9 32.5 28.5 50.9 45.0 37.8 39.4 46.8 42.6 36.3 50.1 43.6 50.1 48.4 41.2 50.2 50.2 31.5 27.7 27.3 41.2 85.6 39.9 53.2 29.6 32.1 72.6 77.7 52.9 40.3 72.7 27.0 48.8 38.4 43.9 58.8 53.1 31.3 43.8 41.8 40.1 38.6 42.5 37.9 42.8 29.8 51.6 60.1 32.7 41.9 44.6 44.9 26.2 44.1 32.8 29.8 19.5 28.5 19.4 48.4 34.0 37.8 63.3 64.8 84.0 39.3 52.2 71.3 61.2 57.8 49.6 54.6 31.2 84.6 71.8 30.6 48.2 38.9 56.8 49.6 33.4 25.0 27.1 42.7 43.0 48.5 42.2 39.8 76.7 42.5 57.5 45.4 75.7 41.9 35.1 31.3 70.7 52.9 71.5 32.9 48.8 79.5 23.1 44.0 35.2 34.5 79.3 42.6 42.5 24.0 47.3 45.6 47.5 42.7 36.1 48.8 46.8 42.2 74.4 35.1 70.5 61.1 87.0 103.5 21.7 56.9 44.4 50.7 15.9 29.8 23.8 24.9 22.2 28.5 23.9 21.0 23.8 22.6 26.2 20.3 21.3 32.8 19.5 24.4 44.1 22.0 19.4 26.9 28.5 37.8 39.4 27.7 27.3 29.6 32.1 27.0 29.8 11.9 16.3 75.4 50.7 37.2 17.1 7.8 66.2 16.0 11.4 61.1 31.4 147.4 28.2 75.5 15.3 39.1 147.7 0.0 111.1 158.0 54.4 53.8 41.5 78.4 82.6 9.5 56.6 52.2 73.7 39.6 72.8 59.1 50.6 87.4 103.8 61.8 88.9 99.5 68.2 54.0 21.2 38.8 46.2 36.5 51.7 33.1 120.0 55.4 107.3 50.1 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050470-2185395 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;placenta: 93.0" "Group enriched" "Detected in many" 4 "Late spermatids: 539.8;Syncytiotrophoblasts: 926.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "eosinophil: 15.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Cell line enhanced" "Detected in many" "BEWO: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.2 7.8 15.9 3.0 31.8 1.4 3.9 39.8 43.6 3.2 8.6 17.1 2.3 20.0 1.7 5.5 10.1 6.5 3.1 6.4 15.5 6.4 11.3 6.8 22.3 5.0 12.2 23.6 1.9 8.5 9.8 12.0 93.0 27.3 5.8 7.5 2.6 7.0 3.0 0.4 8.8 18.4 1.2 8.4 6.9 6.1 17.5 13.5 0.6 14.1 0.9 5.0 4.0 4.6 0.4 0.3 15.0 0.3 0.8 2.6 0.3 7.3 4.7 1.7 8.7 0.0 0.0 23.0 0.5 0.2 5.5 0.3 11.9 16.0 0.0 14.6 1.8 4.8 12.9 9.9 12.3 3.9 0.5 11.0 0.0 7.6 15.8 1.6 0.0 5.7 0.3 7.4 0.0 4.2 0.0 0.0 1.9 3.2 0.1 0.1 9.0 0.4 0.0 3.3 20.2 11.4 0.0 0.0 2.5 9.4 7.8 12.0 9.7 6.0 13.4 2.5 14.9 9.4 2.0 0.0 0.0 6.9 0.0 0.0 3.5 0.6 0.1 0.6 0.1 8.3 0.3 0.0 15.0 0.6 0.3 2.6 0.3 1.0 0.6 0.0 0.4 0.8 0.4 1.2 0.8 0.0 0.3 0.8 0.3 15.9 31.8 39.8 43.6 15.5 6.4 12.2 23.6 27.3 13.5 113.2 71.1 0.8 10.2 11.6 22.8 1.2 2.5 21.4 26.1 7.0 3.9 84.1 6.6 10.9 181.6 6.0 56.7 0.0 9.3 48.8 3.1 16.4 8.1 12.5 12.7 58.8 9.8 6.7 1.0 539.8 8.9 3.3 6.8 5.4 22.1 15.6 12.2 31.6 8.1 19.0 21.6 0.0 2.2 15.8 26.8 11.7 926.6 7.7 25.3 11.9 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Distal tubular cells: 24.9;Early spermatids: 31.1;Erythroid cells: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 18.2;fHDF/TERT166: 19.3;HSkMC: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 7.4 10.6 8.0 5.3 9.7 0.7 19.0 4.9 8.9 5.1 8.7 5.1 24.1 3.1 8.3 9.0 3.5 6.8 9.0 6.3 9.8 5.9 15.1 2.3 14.9 1.6 5.6 6.6 15.7 7.3 35.7 9.2 4.5 10.8 20.1 3.5 4.9 3.5 24.4 3.1 2.7 3.5 19.7 16.4 2.4 4.8 16.1 8.6 0.5 8.2 2.9 1.8 14.1 12.2 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.6 4.1 18.2 17.0 0.1 12.3 9.5 12.6 6.8 0.0 0.5 0.0 1.2 19.3 4.3 0.1 6.0 1.4 6.9 0.0 4.2 0.0 0.1 0.4 9.2 0.0 0.1 18.0 0.6 0.9 1.5 6.5 2.5 0.0 1.2 0.4 11.8 1.4 0.0 0.0 2.5 0.0 6.4 0.0 7.1 3.2 13.5 5.7 3.6 7.2 2.1 0.0 4.7 4.9 0.0 0.1 6.4 12.0 4.9 1.0 3.5 0.0 0.0 0.0 3.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 8.0 9.7 4.9 8.9 9.8 5.9 5.6 6.6 10.8 8.6 0.0 6.1 0.0 3.8 0.5 1.2 1.4 7.6 0.0 0.0 12.2 5.9 0.0 24.9 1.5 31.1 4.5 0.0 23.3 3.6 0.1 3.8 16.3 0.0 1.5 0.2 1.6 2.9 12.3 2.6 12.4 6.9 0.3 6.8 0.0 0.2 16.1 3.2 0.0 12.0 3.7 2.8 0.0 4.7 3.4 4.9 0.6 0.2 0.0 0.0 0.9 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 58.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 17.1 7.6 7.0 25.8 6.5 18.1 18.0 2.5 6.8 16.8 13.7 5.8 18.7 13.7 14.8 16.5 23.4 15.6 17.4 7.4 6.3 3.1 13.2 9.1 21.3 24.8 7.5 2.7 17.0 12.5 10.3 17.2 20.1 6.6 14.8 7.7 11.9 15.6 21.5 7.5 26.8 19.8 11.7 6.8 34.8 15.2 6.6 7.2 41.5 18.7 10.5 33.0 17.4 37.5 6.6 0.4 7.3 1.0 2.9 6.1 1.9 8.8 13.7 5.4 6.6 4.5 3.6 7.0 4.6 7.3 9.6 10.6 7.6 8.6 10.3 8.1 6.1 5.2 13.2 4.8 12.3 3.0 8.7 7.1 10.8 4.2 3.9 6.0 7.9 16.1 4.4 6.0 5.5 4.7 7.2 16.9 9.7 6.9 14.9 3.9 9.3 15.1 25.6 4.6 12.8 7.0 9.9 2.6 16.7 5.9 13.2 3.5 11.0 8.6 7.2 1.8 5.9 5.7 3.1 8.0 4.1 8.2 3.4 3.7 14.6 58.2 5.1 4.3 6.5 4.3 0.9 1.0 3.4 5.6 0.9 4.9 6.1 5.7 6.1 0.4 6.6 5.1 4.9 7.3 2.9 0.7 0.0 4.0 1.9 7.0 6.5 2.5 6.8 6.3 3.1 7.5 2.7 6.6 7.2 8.9 13.5 45.5 26.8 19.6 5.8 11.5 17.8 4.0 10.3 8.7 0.0 11.1 6.6 16.0 0.9 29.2 30.9 23.3 24.3 11.4 10.0 21.5 13.9 7.3 7.7 1.6 20.7 36.2 12.7 2.4 10.9 7.2 11.8 5.4 17.7 6.1 22.1 24.6 6.3 7.1 4.5 12.9 5.9 2.8 15.8 23.3 24.8 23.0 11.2 24.6 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324808 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favorable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 16.1 22.1 9.5 20.7 10.7 5.3 35.1 4.8 9.2 17.2 18.0 7.2 7.2 6.0 19.2 16.0 9.8 11.3 10.0 11.6 12.7 6.1 9.9 8.4 20.4 22.3 11.4 3.7 15.0 7.6 12.9 20.7 11.1 10.3 14.4 8.3 27.8 11.1 13.3 19.1 11.5 12.1 16.5 15.4 22.0 10.5 16.8 10.8 16.2 11.8 9.3 21.2 12.4 17.7 16.4 8.2 5.7 8.3 6.3 11.5 3.4 12.8 5.4 14.5 11.9 11.1 18.6 10.6 8.3 15.5 9.4 9.6 8.7 4.5 18.8 7.0 12.4 14.1 5.1 9.8 10.2 12.7 24.3 14.4 12.4 8.4 5.8 4.5 8.8 7.6 8.8 5.2 14.9 9.8 8.7 16.7 6.3 10.4 23.2 10.9 2.1 3.8 6.9 15.3 0.1 5.3 13.0 22.9 16.1 6.2 14.4 10.9 28.3 8.0 4.6 48.8 7.8 4.9 8.1 16.1 27.0 14.0 10.7 9.3 26.5 49.1 22.0 9.4 3.7 16.2 5.7 8.3 5.5 10.5 6.6 9.1 12.4 8.8 8.4 7.8 16.4 10.4 11.5 1.5 6.3 3.3 8.2 4.1 3.4 9.5 10.7 4.8 9.2 12.7 6.1 11.4 3.7 10.3 10.8 38.7 16.2 38.3 20.7 33.7 29.6 7.1 15.3 5.3 13.6 17.4 64.8 9.1 3.3 10.9 42.2 44.7 5.4 0.0 9.0 28.2 34.8 27.0 77.1 11.3 11.1 41.3 18.1 38.1 28.4 78.9 31.1 24.5 47.2 12.6 6.1 16.0 12.3 3.5 29.0 7.1 110.0 25.8 26.9 56.0 44.5 20.8 8.1 27.4 11.0 32.3 PRKDC "DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic polypeptide" P78527 8 47773108-47960183 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm NA NA 1100000 Nucleoplasm "CAB005167: AB_2172845, HPA035174: AB_2674504" "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 21.3 20.5 16.0 22.3 22.0 27.4 30.2 16.5 23.1 19.6 20.6 17.3 18.1 12.0 26.2 14.5 27.4 24.4 13.0 21.1 20.8 15.2 16.7 18.4 17.0 33.6 16.6 18.2 24.6 23.8 33.4 29.4 20.5 17.3 17.9 20.3 17.8 17.9 17.8 34.0 23.9 18.4 27.0 20.3 24.4 19.1 20.5 15.9 44.4 20.8 15.9 27.9 21.3 19.1 17.0 13.9 7.1 11.5 11.5 11.3 2.3 32.9 28.2 27.5 26.1 17.1 18.2 11.6 14.0 13.8 19.8 19.5 18.4 10.9 31.5 12.2 17.2 14.7 18.8 36.3 19.2 31.0 6.9 22.5 61.8 25.4 22.5 7.4 23.5 12.9 13.1 6.3 31.1 32.7 7.6 20.3 21.9 41.1 13.3 21.8 15.5 33.1 19.4 30.2 23.1 8.6 16.2 21.6 11.1 9.9 28.4 13.8 17.5 43.3 14.1 13.6 17.7 20.2 16.2 23.5 25.9 22.0 20.4 28.1 11.6 14.8 45.3 14.6 26.7 20.9 6.7 8.1 3.5 8.7 6.3 10.9 12.6 10.8 8.8 5.9 17.0 11.3 10.3 7.1 11.5 11.5 13.9 7.4 2.3 16.0 22.0 16.5 23.1 20.8 15.2 16.6 18.2 17.3 15.9 35.7 26.0 39.5 30.4 34.1 100.6 65.8 25.5 52.2 39.8 40.1 117.8 48.3 14.9 34.6 26.1 40.5 10.5 0.0 30.9 53.5 37.0 37.2 43.9 39.8 32.1 98.5 24.8 33.7 41.6 10.8 52.6 32.7 18.6 29.7 26.8 69.1 30.3 14.0 65.4 18.7 102.0 51.8 28.8 106.0 117.5 35.5 27.6 38.3 45.0 27.8 PRKG1 "PGK, PKG, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase, cGMP-dependent, type I" Q13976 10 50990891-52298350 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 43.8;Late spermatids: 40.9;Peritubular cells: 37.1;Sertoli cells: 38.8;Smooth muscle cells: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "basophil: 8.0" "Lineage enriched" "Detected in single" 24 "granulocytes: 8.0" "Cell line enhanced" "Detected in many" "AN3-CA: 11.6;BJ hTERT+: 15.9;fHDF/TERT166: 13.1;U-138 MG: 9.7;U-87 MG: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA 33000 "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 8.0 10.9 5.2 6.6 7.3 0.8 6.9 2.8 5.4 19.2 14.4 2.1 6.8 2.9 22.8 10.7 6.0 9.9 12.6 14.8 7.0 4.9 4.4 2.1 19.5 2.6 3.1 4.8 8.9 2.6 13.7 8.4 11.0 4.6 9.5 6.2 6.2 6.4 9.4 24.9 2.8 5.3 28.2 2.7 2.7 5.9 5.0 3.1 0.2 9.2 12.7 1.2 13.4 15.8 0.1 0.1 8.0 0.1 0.3 0.0 0.1 0.0 0.1 1.5 11.6 5.6 5.3 0.0 5.0 15.9 1.6 2.4 0.1 0.8 0.2 0.0 13.1 1.7 0.1 0.0 0.0 1.5 0.0 4.3 0.8 0.3 0.0 4.8 0.0 0.0 6.8 0.0 4.2 0.1 0.4 0.0 0.0 0.0 0.1 4.4 0.1 0.0 0.0 3.3 0.0 2.0 0.0 3.1 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.1 1.6 0.1 0.0 0.0 9.7 1.7 4.9 2.9 1.2 0.6 0.0 8.6 0.0 2.0 8.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.1 5.2 7.3 2.8 5.4 7.0 4.9 3.1 4.8 4.6 3.1 14.9 9.6 0.0 1.4 0.8 6.8 29.7 0.0 1.4 0.0 3.5 0.0 0.8 0.0 1.8 43.8 3.7 2.6 0.0 3.3 0.9 13.0 0.4 4.6 0.0 0.3 0.0 0.0 4.3 0.0 40.9 30.2 0.3 3.3 0.0 4.3 23.0 3.5 11.4 37.1 0.0 1.3 38.8 47.0 0.7 0.6 0.5 1.8 0.0 3.2 0.7 PRKG2 "cGKII, PRKGR2" ENSG00000138669 "Protein kinase, cGMP-dependent, type II" Q13237 4 81087370-81215117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.3" "Cell type enhanced" "Detected in some" 22 "Alveolar cells type 1: 32.8;Enterocytes: 13.8;Paneth cells: 8.6" "Cancer enhanced" "Detected in some" "melanoma: 4.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.0;MAIT T-cell: 2.2" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "ASC diff: 5.2;ASC TERT1: 4.0;HEL: 20.8;hTCEpi: 4.1;SCLC-21H: 6.4" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" 4.7 0.4 5.2 0.4 2.9 0.6 2.2 0.8 5.3 1.4 7.7 1.2 0.7 12.2 0.6 0.6 3.8 0.6 0.4 6.3 2.9 3.3 0.7 0.3 4.3 0.3 2.5 1.9 0.3 1.8 0.0 12.1 0.2 9.3 12.7 3.8 1.4 0.8 4.6 0.3 2.1 34.3 0.7 1.3 0.3 1.3 1.7 2.4 0.0 1.3 0.0 0.6 1.2 1.3 0.4 0.0 2.0 0.0 0.4 2.2 0.4 0.1 0.3 0.1 0.0 5.2 4.0 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.0 0.2 0.9 0.0 0.1 0.3 1.6 0.0 0.4 0.0 20.8 0.6 0.0 0.0 0.0 0.0 0.6 4.1 0.0 0.0 1.1 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.1 0.0 0.9 6.4 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 2.2 0.2 0.5 0.3 0.0 0.4 0.8 0.9 0.0 0.4 0.0 0.0 0.0 0.4 5.2 2.9 0.8 5.3 2.9 3.3 2.5 1.9 9.3 2.4 32.8 1.6 0.0 0.6 0.0 0.0 2.6 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.1 5.3 0.0 13.8 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.6 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.2 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347420-162727771 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.8" "Cell type enhanced" "Detected in some" 16 "Alveolar cells type 1: 8.9;Alveolar cells type 2: 7.4;Distal tubular cells: 16.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 3.7;HEL: 9.2;Karpas-707: 5.9;RPMI-8226: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: AB_2732471" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favorable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 6.8 7.1 7.9 2.3 12.2 1.5 4.2 7.2 13.4 5.3 4.3 6.3 4.6 2.8 7.8 4.4 6.1 3.4 4.3 17.7 9.2 6.2 17.4 3.6 2.6 3.0 5.8 5.2 6.4 3.0 5.6 8.6 2.0 5.5 4.0 2.4 8.3 3.5 4.8 41.8 4.0 3.3 6.6 5.9 2.7 3.5 10.3 6.8 0.6 3.8 4.7 2.7 4.9 2.1 4.6 1.2 4.2 0.8 1.8 4.6 1.3 0.1 0.3 1.3 3.7 0.9 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 0.9 0.0 0.2 0.2 0.0 0.4 0.6 9.2 0.2 0.0 0.9 0.2 0.1 3.2 0.1 0.0 0.5 0.6 0.0 0.4 0.4 5.9 1.0 0.5 0.1 0.1 0.2 0.6 0.9 0.0 0.0 5.9 0.7 0.1 1.0 2.5 0.0 0.0 0.3 1.2 0.0 0.6 0.0 0.1 0.3 0.1 0.3 0.8 0.1 0.0 0.1 0.2 2.2 2.8 0.8 4.2 2.1 0.5 3.5 1.5 2.0 2.2 1.2 4.6 4.4 4.6 1.5 1.8 0.4 0.3 0.2 1.3 7.9 12.2 7.2 11.7 9.2 6.2 5.8 5.2 5.5 6.8 8.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.4 1.8 0.0 0.4 16.6 0.8 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 2.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 PRKX PKX1 ENSG00000183943 "Protein kinase, X-linked" P51817 X 3604370-3713608 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "granulocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 38.8" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm No No Nucleoplasm "HPA015324: AB_1855715" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.45e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (4.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-3)" "unprognostic (2.15e-2)" "unprognostic (9.91e-2)" "unprognostic (2.52e-1)" "unprognostic (1.70e-2)" 4.3 1.3 12.3 7.5 15.8 5.4 11.2 4.4 12.3 6.9 5.2 5.4 11.5 4.1 7.3 8.4 13.6 16.5 3.9 4.0 14.0 7.4 14.2 2.0 8.4 9.5 27.9 5.6 4.8 4.1 3.2 2.3 6.6 22.7 3.7 5.2 3.1 6.5 5.3 1.6 9.9 6.0 3.0 17.6 10.0 3.1 6.1 22.7 6.1 28.8 3.2 8.0 3.7 11.2 2.5 2.8 12.2 4.1 3.3 3.8 1.7 4.5 4.2 11.6 8.6 2.2 3.0 10.6 2.7 1.0 1.3 1.8 6.2 3.1 0.4 2.7 2.1 2.8 3.1 10.7 8.1 2.3 5.0 7.5 5.0 3.2 0.1 2.3 6.4 38.8 2.0 8.7 1.4 5.3 3.7 13.1 6.3 5.8 6.5 4.4 3.9 7.3 5.7 7.7 3.5 4.8 13.7 11.1 8.5 10.7 3.8 7.8 5.0 2.8 1.8 2.7 19.0 1.4 5.1 7.1 1.2 2.0 1.9 1.8 0.1 0.3 5.8 0.7 5.8 3.0 12.2 3.1 1.8 3.5 3.3 3.8 2.5 3.7 3.3 2.3 2.4 3.1 3.3 0.8 3.3 4.1 2.8 2.5 1.7 12.3 15.8 4.4 12.3 14.0 7.4 27.9 5.6 22.7 22.7 3.0 13.1 6.5 16.9 19.1 0.6 1.4 25.5 17.4 9.1 5.2 0.0 17.4 11.6 10.4 7.2 17.0 7.7 0.0 2.7 3.8 9.7 9.1 85.2 1.7 15.1 1.6 4.6 11.1 19.0 34.3 18.4 20.8 5.0 6.4 11.4 2.1 4.7 10.5 20.5 5.1 0.7 32.3 22.0 1.6 21.7 23.5 6.5 25.5 22.2 16.5 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favorable (6.82e-5)" 23.2 21.6 19.6 24.0 20.5 8.5 21.4 35.6 26.8 18.3 19.3 6.0 14.7 12.0 22.2 14.2 23.6 14.7 13.6 16.3 16.5 11.7 15.0 14.5 13.0 15.4 14.5 14.1 19.1 14.4 20.9 30.9 17.1 21.0 14.9 15.7 5.3 22.7 20.4 45.7 16.3 16.4 14.9 23.7 19.0 13.6 11.6 20.2 21.8 21.1 11.3 17.4 21.4 22.2 9.7 13.6 7.5 11.9 11.8 9.1 3.9 14.7 12.8 20.2 13.8 11.5 10.7 9.8 14.3 15.7 15.6 15.8 12.2 7.5 24.1 18.0 16.1 12.8 13.2 25.4 12.4 22.5 11.3 18.6 27.1 14.7 10.9 8.8 29.9 14.8 9.7 8.2 11.1 6.9 7.6 15.5 11.8 37.1 8.9 15.3 8.6 21.9 10.0 12.1 12.9 11.9 24.9 19.5 23.4 10.0 16.6 15.7 10.3 16.6 10.4 12.6 16.8 16.2 15.0 16.6 15.4 8.9 10.1 13.8 10.1 15.8 28.1 8.4 13.7 18.7 7.5 11.9 3.6 7.6 9.9 9.1 9.7 8.6 9.0 10.2 9.3 8.0 8.0 6.1 11.8 8.7 13.6 6.3 3.9 19.6 20.5 35.6 26.8 16.5 11.7 14.5 14.1 21.0 20.2 101.3 91.8 89.2 53.8 74.1 81.8 69.0 61.1 89.7 101.2 92.5 84.4 51.4 61.3 56.7 8.7 82.4 58.2 46.7 49.5 40.6 50.2 53.8 86.8 76.7 36.1 100.1 72.3 68.2 59.0 11.9 91.5 57.7 33.7 71.3 57.5 80.9 52.5 57.5 83.8 50.1 181.0 58.2 43.9 67.7 79.4 79.8 53.2 69.3 57.5 63.7 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease mutation, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.7" "Cell type enhanced" "Detected in many" 12 "Bipolar cells: 79.8;Cone photoreceptor cells: 29.5;Leydig cells: 33.4;Peritubular cells: 37.8;Rod photoreceptor cells: 40.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11 "NK-cell: 7.3" "Lineage enriched" "Detected in single" 11 "NK-cells: 7.3" "Cell line enhanced" "Detected in many" "AF22: 19.8;hTERT-RPE1: 12.2;REH: 15.1;U-138 MG: 13.7" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 3.7 7.2 27.2 2.8 40.5 0.8 2.1 86.7 53.6 10.1 6.0 6.0 3.1 6.2 20.7 8.3 4.4 10.2 10.3 5.3 18.9 13.0 2.1 0.9 5.7 3.5 5.5 33.2 35.7 2.4 8.6 17.6 7.1 18.0 16.2 2.6 5.2 4.6 14.4 4.3 3.1 6.8 10.3 7.4 1.8 7.3 9.9 10.2 0.0 2.8 0.3 1.6 5.1 10.7 0.2 0.0 0.5 0.2 7.3 0.6 0.3 0.3 1.2 19.8 7.4 1.0 3.7 0.5 2.4 4.0 0.8 0.9 1.1 2.3 0.2 0.4 3.2 0.6 2.0 2.7 0.4 0.3 5.2 1.6 1.3 8.8 0.8 0.2 0.0 0.3 3.4 0.1 1.4 0.1 12.2 1.0 0.6 0.2 1.6 0.6 3.3 0.5 0.6 5.7 0.0 1.0 15.1 1.1 0.4 0.1 0.7 4.3 4.5 0.2 2.9 0.4 3.2 7.3 0.1 1.1 13.7 4.8 0.8 1.3 3.4 0.4 0.1 5.4 0.1 0.5 0.5 0.0 0.1 0.2 0.1 0.3 0.1 0.6 0.4 0.0 0.2 0.4 0.2 0.2 7.3 0.2 0.0 0.1 0.3 27.2 40.5 86.7 53.6 18.9 13.0 5.5 33.2 18.0 10.2 3.0 0.0 0.0 1.3 1.0 79.8 0.8 0.0 6.7 1.2 0.0 29.5 1.5 1.7 1.1 1.7 2.0 9.6 0.0 1.4 0.6 9.3 1.4 0.0 0.0 0.3 19.1 5.8 2.5 0.0 6.3 33.4 0.0 0.0 1.0 2.0 6.5 2.3 10.5 37.8 0.2 40.1 6.5 13.2 2.4 3.2 0.4 2.2 0.0 1.7 1.0 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893272-67929678 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "HPA053927: AB_2682312, HPA062763: " "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favorable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.3 13.6 14.0 16.6 4.8 15.1 13.3 13.3 11.0 14.7 17.7 24.0 14.0 19.2 14.6 17.7 20.2 19.3 17.8 12.2 8.4 18.8 15.1 13.1 10.4 16.2 12.7 21.2 35.3 33.2 13.0 9.8 16.1 14.3 11.4 16.2 19.0 14.8 19.9 14.0 15.2 16.3 11.3 12.8 19.1 31.7 15.0 12.5 14.9 12.9 8.6 14.8 18.7 4.0 5.2 4.5 5.8 5.2 5.6 3.5 7.4 13.3 15.2 16.7 23.6 12.0 9.8 9.0 13.7 9.6 8.5 10.0 10.8 7.0 13.7 15.1 7.6 11.3 8.7 9.2 3.2 2.7 9.8 8.0 9.9 12.7 16.2 7.6 4.8 22.0 16.1 11.3 11.9 12.9 13.9 13.3 12.2 3.0 9.9 16.6 10.3 4.9 14.5 8.1 8.3 15.9 5.8 14.5 11.2 9.3 13.2 15.7 27.9 7.6 9.1 6.3 14.0 13.9 12.2 10.8 3.8 9.0 4.5 9.2 4.9 15.2 13.0 5.1 11.8 0.0 4.3 4.5 5.6 5.8 3.8 4.0 3.9 5.3 5.2 3.5 3.4 4.3 2.7 5.2 3.6 3.8 2.3 3.5 13.6 16.6 13.3 13.3 12.2 8.4 16.2 12.7 16.1 15.0 0.0 2.2 5.1 2.5 1.0 10.7 1.7 7.6 4.0 2.3 5.2 5.9 5.2 10.0 5.5 10.8 2.9 8.1 0.0 6.5 4.0 3.9 3.5 5.8 7.7 4.1 6.4 10.4 4.3 5.6 16.9 4.4 1.2 5.0 3.6 6.3 8.2 6.9 3.5 7.4 6.3 6.7 12.9 4.7 3.5 5.7 1.4 4.9 3.1 6.3 1.4 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86048373-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;placenta: 1.2;testis: 2.0" "Cell type enhanced" "Detected in single" 35 "Rod photoreceptor cells: 1.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "HEL: 14.3" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase, mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Late spermatids: 522.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 24.0 24.5 22.3 13.1 23.2 19.8 23.3 16.5 25.2 15.7 14.8 18.5 17.5 14.6 14.7 21.4 14.3 16.9 17.9 17.1 18.5 21.9 20.1 21.8 25.1 16.7 23.1 16.2 15.7 39.3 18.3 18.7 21.8 14.4 15.8 11.5 20.1 26.4 19.5 23.4 11.2 13.1 12.7 17.6 14.7 16.9 44.6 10.3 10.8 19.9 15.7 15.0 11.0 11.5 20.4 40.8 22.1 24.4 15.4 17.5 16.8 22.2 12.6 1.5 10.1 11.7 9.0 4.3 13.1 12.4 13.1 12.5 20.9 11.9 16.0 14.5 9.8 12.2 19.1 10.4 13.6 14.0 19.5 31.3 7.4 25.8 26.3 17.2 14.3 9.8 8.9 15.5 6.1 18.8 10.1 9.3 15.9 18.8 12.3 9.6 42.0 12.2 18.5 9.4 3.8 23.4 22.4 8.5 13.7 15.8 14.3 9.4 11.5 19.9 7.3 11.8 6.6 33.8 15.4 10.0 9.7 15.0 15.7 19.7 18.7 12.5 10.9 7.6 12.4 5.9 6.0 24.4 22.1 16.0 20.9 15.4 20.4 15.2 17.3 27.7 18.0 15.2 14.4 1.9 15.4 19.4 40.8 17.5 16.8 22.3 23.2 16.5 25.2 18.5 21.9 23.1 16.2 14.4 10.3 20.8 25.4 25.3 13.5 15.9 13.5 5.3 48.4 41.5 22.7 38.4 3.9 63.4 61.3 87.9 188.7 19.1 21.4 0.0 74.6 54.2 24.4 20.5 16.2 36.5 56.1 4.8 30.1 30.1 29.8 522.3 43.1 32.4 43.9 60.5 41.0 48.4 92.6 28.1 43.9 62.0 11.6 19.4 21.2 109.7 21.3 15.2 64.2 24.9 61.2 18.6 PTRH1 "C9orf115, PTH1" ENSG00000187024 "Peptidyl-tRNA hydrolase 1 homolog" Q86Y79 9 127690348-127724873 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021223 Uncertain NA NA "HPA021223: AB_1845798" "unprognostic (6.58e-2)" "unprognostic (7.01e-3)" "unprognostic (3.46e-3)" "unprognostic (2.53e-2)" "unprognostic (7.05e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (3.90e-2)" "unprognostic (1.74e-1)" "unprognostic (6.58e-3)" "unprognostic (8.67e-2)" "unprognostic (4.08e-2)" "unprognostic (5.98e-3)" "unprognostic (5.74e-4)" "unprognostic (1.38e-2)" "unprognostic (1.91e-1)" "unprognostic (1.72e-2)" 14.9 15.0 12.5 8.3 11.9 7.1 9.1 3.9 13.7 9.4 7.8 10.7 12.9 7.7 7.8 16.1 7.8 9.9 12.6 13.1 10.7 9.4 14.5 19.3 7.5 14.7 11.6 8.5 6.2 24.7 8.8 11.0 7.2 8.9 9.9 4.0 8.3 9.3 9.9 13.0 15.1 5.8 6.4 6.2 9.4 12.4 16.1 6.2 7.1 18.8 9.1 5.7 9.4 5.6 8.7 11.4 5.6 14.4 10.5 29.4 12.8 15.9 7.1 1.6 4.4 2.3 3.0 12.5 10.6 2.9 4.1 2.2 3.7 6.0 6.0 14.3 4.4 5.5 17.6 1.3 7.7 1.2 8.7 2.4 2.6 8.9 7.1 6.9 3.9 7.2 2.5 8.0 4.9 5.1 2.2 8.1 8.4 6.8 4.8 4.6 14.7 7.0 5.8 2.2 14.6 32.3 6.1 3.5 13.6 7.4 3.5 7.1 6.5 11.4 13.7 8.0 1.5 12.3 2.5 9.6 5.9 8.2 20.9 6.6 14.4 7.7 3.9 7.9 3.0 7.1 2.5 13.2 5.6 29.3 14.4 29.3 8.7 15.1 29.4 11.4 7.2 11.1 25.5 1.7 10.5 7.5 10.4 14.2 12.8 12.5 11.9 3.9 13.7 10.7 9.4 11.6 8.5 8.9 6.2 3.0 7.8 12.4 33.6 15.0 22.3 0.3 25.5 46.8 6.8 45.4 43.2 11.0 56.3 56.3 53.7 19.7 8.1 0.0 29.3 19.6 18.8 39.9 17.3 25.2 41.1 15.9 28.9 19.0 9.1 11.4 20.4 13.7 15.1 17.2 19.3 20.7 39.4 10.4 88.4 101.3 60.3 0.0 21.5 27.4 7.9 18.4 15.7 20.3 16.6 30.8 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 15.9 22.9 17.1 12.4 17.1 9.9 20.7 12.5 22.1 15.6 17.2 11.8 16.3 11.6 14.3 36.7 16.4 13.8 13.1 12.6 19.3 17.8 14.8 34.7 12.1 12.5 16.7 15.2 14.2 19.9 10.3 18.3 13.6 21.0 15.9 20.7 8.1 13.7 18.7 23.3 11.4 11.0 16.8 17.1 15.5 14.3 15.7 18.1 9.0 11.8 13.5 16.9 13.0 10.5 15.6 21.6 12.6 29.3 13.1 15.5 13.0 18.9 36.2 11.7 10.6 22.2 19.1 12.5 18.3 16.1 15.7 23.0 23.4 14.9 13.8 27.8 15.3 26.9 18.9 25.1 23.6 22.9 26.5 34.1 24.6 18.8 42.8 34.3 21.7 14.0 21.5 30.7 24.3 28.3 11.2 26.1 9.7 27.4 15.4 23.3 45.8 18.5 17.7 10.0 49.3 28.7 10.1 19.6 20.1 26.1 27.3 15.1 19.6 9.4 10.3 22.4 14.0 24.1 15.5 17.1 20.5 20.7 12.2 19.8 20.0 22.2 20.4 13.5 13.6 15.6 1.9 25.8 1.1 9.2 24.4 12.4 15.6 10.8 10.4 18.5 13.1 15.5 11.1 12.6 13.1 29.3 21.6 12.3 13.0 17.1 17.1 12.5 22.1 19.3 17.8 16.7 15.2 21.0 18.1 14.9 12.8 13.4 31.9 32.5 3.3 14.8 7.6 30.8 50.0 10.4 3.9 22.1 10.0 25.9 17.7 18.3 9.1 0.0 22.0 20.6 19.7 23.3 22.0 27.3 15.2 7.9 6.4 11.6 7.3 7.9 16.1 18.7 13.5 10.0 9.7 6.6 25.9 13.9 9.2 13.2 3.2 12.9 21.7 16.7 11.4 31.1 26.5 8.3 13.2 31.5 PUS1 ENSG00000177192 "Pseudouridylate synthase 1" Q9Y606 12 131929200-131945896 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Isomerase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051636, HPA057593" Approved Supported Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA051636: AB_2681560, HPA057593: AB_2683479" "unprognostic (2.72e-1)" "unprognostic (9.13e-2)" "unprognostic (1.81e-1)" "unprognostic (2.69e-2)" "unprognostic (8.12e-3)" "unprognostic (8.07e-2)" "unprognostic (4.57e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (2.06e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (3.49e-8)" "unprognostic (1.80e-3)" "unprognostic (8.06e-2)" "unprognostic (8.59e-2)" "unprognostic (1.56e-2)" 12.7 15.8 18.8 19.5 23.3 26.2 11.2 8.8 16.9 8.7 11.9 9.4 11.0 12.4 13.6 18.7 16.5 12.9 25.1 8.6 15.6 8.3 10.7 22.8 11.0 21.4 11.7 15.8 10.1 19.8 7.2 9.5 8.3 11.7 11.7 10.5 7.6 11.4 15.7 13.5 15.4 13.9 9.7 6.2 17.4 13.6 11.9 16.4 11.6 10.3 11.6 15.8 10.8 12.8 5.9 4.6 1.9 2.0 9.1 4.0 1.3 15.4 20.2 4.8 8.5 4.6 7.9 29.5 11.9 5.0 9.1 5.9 22.3 10.1 18.4 13.8 6.5 7.1 19.6 15.8 11.3 5.9 8.1 31.9 18.5 9.8 19.4 12.5 31.7 17.1 8.0 9.2 10.4 8.9 4.4 8.9 12.9 22.9 5.7 5.2 26.8 20.8 28.5 25.3 12.6 30.8 19.9 6.8 19.1 7.4 21.5 13.4 7.5 10.0 13.7 11.0 4.9 15.0 34.3 7.7 7.3 15.6 15.4 17.2 15.6 11.7 21.9 7.5 25.4 10.0 1.2 2.0 0.4 3.2 1.4 2.2 5.9 2.7 3.3 1.6 5.5 4.0 2.1 1.9 9.1 1.3 4.6 2.4 1.3 18.8 23.3 8.8 16.9 15.6 8.3 11.7 15.8 11.7 16.4 0.0 6.7 10.0 16.1 26.3 5.2 4.5 12.7 4.0 3.4 5.2 21.6 12.0 5.0 9.3 0.6 9.0 4.5 0.0 8.2 14.4 9.6 13.4 16.1 11.3 13.6 0.0 13.8 8.0 7.3 2.0 7.2 8.9 6.8 8.2 17.2 4.6 12.7 7.0 8.9 10.4 9.6 6.5 11.8 16.5 22.1 19.8 7.2 7.5 15.5 13.7 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37344574-37373322 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 77.6;blood: 137.6" "Group enriched" "Detected in many" 6 "Intestinal endocrine cells: 208.4;Melanocytes: 501.0" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "neutrophil: 137.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 137.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.9;SCLC-21H: 24.3;SK-MEL-30: 81.6;U-266/84: 63.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 3.2 77.6 4.3 5.4 5.8 17.0 6.4 1.2 11.6 9.2 11.3 2.2 1.5 2.2 6.2 43.7 2.4 1.9 5.5 2.9 6.7 17.9 12.4 1.3 6.1 7.4 3.9 5.0 1.4 5.5 9.6 31.6 7.8 5.9 3.5 4.2 21.2 14.7 2.8 4.0 14.2 2.3 3.4 3.0 8.5 3.4 2.6 0.5 2.3 1.8 4.4 4.8 7.0 2.9 0.2 10.7 137.6 29.7 0.0 0.0 12.1 0.1 8.0 0.0 0.0 1.1 2.7 0.0 1.1 17.9 1.3 2.1 0.5 1.4 0.0 0.6 6.0 15.2 0.0 0.5 0.0 2.1 0.1 15.6 3.6 0.0 1.5 0.1 0.5 0.0 1.5 0.0 9.9 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 8.8 2.2 24.3 0.0 1.3 0.0 81.6 1.6 0.1 0.6 3.8 0.0 0.0 0.0 0.1 3.1 63.8 0.0 5.5 0.0 0.0 0.6 29.7 0.2 0.0 3.4 0.0 0.2 0.0 0.0 10.7 0.1 0.0 0.0 137.6 0.0 0.3 0.2 0.0 12.1 4.3 5.8 1.2 11.6 6.7 17.9 3.9 5.0 5.9 0.5 3.0 2.9 8.2 9.7 34.7 10.9 1.1 2.5 1.4 0.0 21.0 2.0 0.5 1.7 45.4 0.4 7.3 2.0 0.0 2.1 4.3 11.0 9.5 55.3 0.2 21.3 41.3 208.4 22.7 29.2 2.2 2.8 35.6 501.0 10.8 5.8 1.2 25.4 1.9 22.3 4.7 2.9 12.9 15.5 2.1 0.6 12.7 3.9 1.9 6.9 5.5 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Mucus-secreting cells: 232.5;Paneth cells: 244.4;Undifferentiated cells: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA Mitochondria "HPA042695: AB_2678119, HPA048651: AB_2680477, HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favorable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favorable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favorable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavorable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 14.0 18.4 20.6 13.4 29.1 14.2 11.5 18.0 21.3 11.3 14.5 13.3 19.4 12.8 15.3 11.6 14.6 15.8 13.5 19.5 19.7 13.1 11.8 18.9 8.4 13.5 22.9 19.3 22.1 33.9 5.8 12.0 9.8 19.9 13.7 6.6 10.5 26.6 12.7 20.5 12.6 14.2 13.3 12.7 11.5 12.5 5.0 22.2 5.3 19.0 11.9 10.3 12.0 10.3 19.6 19.1 0.9 14.4 18.5 18.8 10.4 17.2 13.9 6.6 19.3 7.0 8.4 8.7 8.8 7.9 10.3 10.2 11.1 6.6 19.5 21.7 5.0 6.2 11.6 6.0 10.6 3.4 11.5 8.4 12.8 5.6 23.3 12.1 19.0 11.3 12.4 9.1 6.7 9.9 4.7 10.5 10.8 14.1 22.4 5.1 26.9 16.3 23.7 17.5 10.8 21.5 17.2 8.8 30.1 8.4 11.1 21.5 9.3 13.5 14.8 11.5 2.9 9.5 8.0 8.1 15.9 8.9 25.4 20.5 24.7 19.0 9.5 8.6 23.1 19.2 0.9 8.3 0.2 15.1 14.4 18.8 19.6 16.3 13.1 16.4 19.0 17.5 13.9 0.6 18.5 7.3 19.1 17.7 10.4 20.6 29.1 18.0 21.3 19.7 13.1 22.9 19.3 19.9 22.2 0.0 5.0 26.7 54.7 56.6 36.4 5.6 28.1 12.0 5.7 54.1 47.1 41.0 54.7 20.6 1.3 27.0 191.9 70.0 23.8 30.6 33.2 38.0 16.1 26.7 26.1 85.8 185.1 16.5 20.2 1.1 46.9 9.6 47.2 7.2 232.5 24.4 15.1 244.4 35.3 58.5 54.3 19.4 30.3 12.1 28.9 36.6 23.5 26.2 247.9 33.9 QTRT2 "FLJ12960, QTRTD1" ENSG00000151576 "Queuine tRNA-ribosyltransferase accessory subunit 2" Q9H974 3 114005833-114088422 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 1: 17.9;Alveolar cells type 2: 16.9;Club cells: 19.4;granulocytes: 14.0;monocytes: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036827, HPA036828" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA Nucleoplasm "Intermediate filaments" "HPA036827: AB_2675336, HPA036828: AB_10696788" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (6.71e-3)" "unprognostic (1.01e-3)" "unprognostic (8.57e-2)" "unprognostic (4.41e-1)" "unprognostic (5.82e-3)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" "unprognostic (6.94e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.95e-4)" "unprognostic (1.44e-1)" "unprognostic (8.74e-2)" "unprognostic (2.65e-2)" "unprognostic (1.98e-1)" "unprognostic (1.18e-3)" 17.1 13.9 8.7 12.4 10.4 13.3 14.1 6.4 10.3 11.0 11.2 14.9 7.9 10.4 16.1 9.2 13.7 13.1 13.6 7.5 6.7 6.7 15.8 15.7 12.2 14.9 11.0 7.6 12.6 15.3 10.7 16.9 11.6 9.4 11.2 12.5 17.7 11.8 9.8 7.5 12.4 12.9 10.8 11.3 19.9 10.7 14.1 10.0 17.3 13.2 10.9 21.6 11.6 10.9 13.9 15.8 5.3 12.9 6.4 6.6 5.0 13.4 14.0 11.7 12.9 5.2 6.4 11.1 7.1 4.5 12.1 11.2 13.3 9.8 25.1 10.4 6.5 14.5 13.5 22.7 10.7 16.0 4.7 10.2 11.3 8.4 9.4 7.4 20.4 10.6 5.0 9.7 11.0 15.7 4.9 12.5 11.7 11.8 9.0 6.8 10.7 17.1 8.0 22.4 19.2 15.4 15.5 8.2 13.5 9.5 9.3 16.0 7.6 10.3 10.2 13.0 10.2 11.3 10.4 8.2 10.6 11.6 4.1 13.7 6.4 9.2 35.1 9.3 15.2 21.3 0.3 12.4 2.9 5.6 12.9 5.3 13.9 4.8 5.5 15.8 9.5 6.6 5.3 5.3 6.4 9.1 6.6 5.9 5.0 8.7 10.4 6.4 10.3 6.7 6.7 11.0 7.6 9.4 10.0 17.9 16.9 0.0 0.0 0.0 0.0 0.0 0.0 8.1 19.4 3.5 0.0 9.4 1.7 13.8 0.0 0.0 0.0 0.0 10.8 8.6 0.0 0.0 14.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 14.4 0.0 0.0 12.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 RAD18 RNF73 ENSG00000070950 "RAD18, E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Nucleoplasm, Nuclear bodies" "HPA006716: AB_2667650, HPA006724: AB_2667655, HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.73e-4)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 6.2 5.7 7.4 5.6 12.7 7.9 9.5 16.4 11.4 5.5 6.6 3.9 5.4 17.7 6.5 3.7 7.6 4.9 5.6 4.4 4.7 3.3 4.3 5.7 5.9 7.6 8.4 6.9 7.1 4.2 3.4 6.9 6.9 5.7 7.4 9.0 3.5 7.5 3.5 3.7 8.5 10.5 6.0 7.8 8.5 5.1 9.5 9.8 16.6 6.7 4.7 7.5 6.1 6.8 3.7 6.3 8.7 3.0 4.3 5.5 1.5 9.9 9.4 7.9 4.7 2.0 4.2 9.7 15.8 5.4 15.2 10.5 8.6 6.4 12.3 3.0 8.9 8.9 3.5 8.3 8.2 15.6 7.6 10.5 10.4 9.5 5.1 1.2 13.7 9.0 1.6 3.0 15.0 10.2 4.1 4.9 10.5 11.1 12.2 13.3 11.5 13.9 9.8 11.0 7.9 17.4 11.1 8.8 9.7 4.4 7.7 3.3 7.5 7.0 6.8 5.1 6.5 7.0 6.1 4.0 12.7 6.9 10.7 13.5 6.2 9.4 26.7 9.3 15.3 9.3 7.4 2.7 8.7 3.0 3.0 5.5 3.7 4.0 5.2 3.4 3.7 4.3 3.2 1.2 4.3 1.8 6.3 5.0 1.5 7.4 12.7 16.4 11.4 4.7 3.3 8.4 6.9 5.7 9.8 14.9 9.8 8.2 5.8 9.8 5.1 2.0 5.1 4.0 9.1 3.5 2.0 6.6 1.7 6.5 3.3 4.2 3.8 0.0 7.1 10.7 4.3 7.0 12.8 2.9 5.9 3.2 1.7 4.9 3.7 2.1 3.7 4.6 3.3 7.2 5.0 2.8 7.9 5.8 2.5 2.4 2.2 6.5 4.7 15.5 13.6 10.3 5.6 4.6 5.2 2.7 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664226 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 53.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002640, CAB019291" Approved Approved "Nuclear speckles" NA NA "Nuclear speckles" "CAB019291: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 19.5 15.6 15.1 14.7 17.1 32.2 17.5 35.2 18.9 19.9 20.3 21.1 19.6 18.4 24.9 15.7 24.6 18.6 20.2 39.3 15.3 11.0 21.7 36.2 19.7 15.7 16.0 13.4 24.9 31.3 30.7 16.9 24.8 14.3 18.8 19.2 25.0 18.3 18.4 79.7 23.9 29.6 23.7 13.8 22.1 23.7 16.7 17.8 27.7 26.9 27.9 26.1 20.5 20.4 6.6 9.3 53.9 9.9 8.5 8.6 7.7 15.4 17.8 27.1 21.0 23.6 19.1 54.6 23.6 40.0 31.3 35.5 13.9 12.8 16.2 11.3 36.5 16.9 9.9 28.5 20.9 32.6 28.3 22.4 21.8 21.4 12.9 23.9 21.2 20.7 17.6 21.2 32.2 26.1 21.6 22.4 24.9 15.8 42.6 30.1 26.4 27.2 15.7 27.6 19.3 24.2 22.0 23.8 20.4 18.7 23.4 8.5 17.8 19.3 18.7 12.5 22.0 31.0 28.1 16.0 21.5 20.5 18.0 26.2 33.2 52.9 34.9 18.5 24.8 22.8 11.3 9.7 18.4 7.4 9.9 7.5 6.6 7.3 7.2 9.3 6.3 7.5 7.6 53.9 8.5 9.6 4.2 8.6 7.7 15.1 17.1 35.2 18.9 15.3 11.0 16.0 13.4 14.3 17.8 20.8 36.5 39.7 31.1 30.6 51.6 25.8 28.1 25.4 21.6 26.2 62.8 34.3 11.6 22.9 7.1 29.1 32.5 0.0 32.0 39.8 32.9 38.2 33.5 36.5 25.2 41.3 28.2 31.3 36.8 3.4 36.2 34.2 25.3 29.7 29.6 32.1 28.8 34.8 38.9 15.7 84.2 32.3 33.0 17.7 27.4 38.0 52.1 38.3 29.5 36.9 RAG1 "MGC43321, RNF74" ENSG00000166349 "Recombination activating 1" P15918 11 36510709-36593156 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA recombination, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Multifunctional enzyme, Nuclease, Transferase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "lymphoid tissue: 462.4" "Cell type enhanced" "Detected in some" 12 "Distal tubular cells: 3.3;Ito cells: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "MOLT-4: 67.2;REH: 64.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA043939 Supported Nucleoplasm NA NA Nucleoplasm "HPA043939: AB_2732512" "unprognostic (7.35e-2)" "unprognostic (1.57e-3)" "unprognostic (8.75e-2)" "unprognostic (3.44e-1)" "unprognostic (2.14e-1)" "unprognostic (1.46e-2)" "unprognostic (2.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.43e-1)" "unprognostic (1.54e-2)" "unprognostic (5.98e-3)" "unprognostic (1.28e-1)" "unprognostic (1.16e-9)" "unprognostic (2.16e-2)" "unprognostic (1.04e-1)" "unprognostic (2.53e-4)" "unprognostic (1.53e-1)" 0.7 2.3 0.5 0.5 0.5 7.4 0.7 0.5 0.5 0.5 0.6 0.5 0.5 1.2 0.5 1.3 0.5 0.6 0.5 0.6 0.5 0.2 2.4 1.2 0.8 0.5 0.5 0.5 0.6 1.1 1.9 0.5 0.8 0.5 0.5 0.4 0.5 1.5 0.5 0.5 0.2 1.5 0.5 0.5 4.4 0.8 0.9 0.5 462.4 4.5 0.5 0.8 0.7 0.5 0.2 0.3 0.0 0.0 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 13.4 0.0 0.0 0.1 0.0 67.2 0.0 0.5 0.0 0.0 64.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.5 0.5 0.5 0.5 0.2 0.5 0.5 0.5 0.5 0.0 0.0 0.0 1.0 0.1 1.2 0.8 0.0 0.0 0.0 1.8 0.0 0.2 3.3 0.4 1.7 1.5 1.4 0.0 0.4 0.1 0.2 0.3 0.0 1.7 0.3 0.0 0.0 9.2 1.6 1.3 0.0 0.0 0.0 1.8 0.6 0.1 0.7 0.0 0.0 2.1 0.8 0.0 0.4 1.2 0.7 0.4 0.3 0.0 0.4 0.5 RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA replication, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" NA NA "Nuclear speckles" "CAB032866: AB_2177791, HPA041725: AB_2677639, HPA043544: AB_2678543" "unprognostic (1.04e-1)" "unprognostic (5.08e-2)" "unprognostic (3.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (6.60e-2)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" 15.1 17.6 17.2 14.0 16.4 81.4 17.9 33.0 15.7 17.8 18.8 16.3 19.8 10.2 23.2 18.7 15.3 21.2 17.6 14.7 15.0 13.2 13.1 15.8 15.7 18.1 18.7 12.2 27.2 14.4 20.7 23.1 73.9 15.4 18.2 14.4 18.4 13.7 14.7 19.2 19.2 16.4 18.4 19.2 18.6 16.4 25.1 18.7 24.3 18.6 11.8 15.5 17.9 17.9 3.8 6.9 8.5 3.7 6.5 4.2 1.0 17.7 9.3 21.9 22.8 16.8 17.6 23.8 14.4 13.3 13.2 14.3 10.3 14.4 24.7 10.9 12.2 15.1 17.2 23.5 12.5 21.9 13.5 18.2 21.3 26.7 29.3 13.1 28.2 12.7 15.2 17.5 17.2 20.3 14.9 18.9 21.7 26.7 22.6 15.2 18.3 22.7 25.5 25.2 12.0 8.8 31.4 22.3 21.7 12.7 15.9 17.6 15.4 20.3 18.2 25.5 25.5 14.2 25.1 16.3 16.4 12.1 14.1 15.4 20.1 20.0 31.2 13.2 18.8 13.5 8.5 2.3 3.7 4.0 3.7 4.2 3.8 4.1 2.8 1.6 3.8 3.5 4.0 5.0 6.5 2.1 6.9 3.1 1.0 17.2 16.4 33.0 15.7 15.0 13.2 18.7 12.2 15.4 18.7 80.4 103.7 61.9 93.7 89.4 65.1 127.0 28.1 61.6 67.1 26.2 94.2 37.6 21.6 42.4 225.8 76.4 57.3 46.7 41.4 46.4 91.5 72.4 49.7 50.4 33.6 58.8 78.7 66.3 46.7 20.2 67.0 54.3 59.1 55.1 59.4 50.8 43.9 28.1 55.2 17.7 56.2 51.8 113.1 66.6 47.7 89.0 84.9 56.5 56.8 89.7 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favorable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favorable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favorable (7.89e-5)" 8.8 12.1 15.7 9.9 20.1 15.6 17.8 20.7 16.8 10.2 12.7 9.8 8.7 9.0 11.0 7.5 8.4 12.9 7.2 17.6 14.1 16.2 17.1 12.5 10.4 12.2 15.9 15.7 16.2 10.6 14.9 13.0 10.5 17.1 12.0 14.2 7.7 12.3 11.3 29.7 5.9 9.2 12.4 16.7 12.2 10.3 13.4 15.4 14.9 20.3 8.0 12.7 9.7 12.1 4.4 7.4 18.9 8.8 4.6 7.4 4.3 6.1 3.2 9.5 8.9 10.0 8.8 5.4 4.1 9.7 8.6 10.2 8.7 7.6 10.2 7.9 5.9 8.5 3.7 24.1 7.3 13.1 8.3 7.9 13.2 6.0 11.1 8.6 17.8 7.3 8.1 9.2 9.9 9.3 10.4 17.3 13.3 12.2 10.4 20.0 9.9 16.3 7.2 15.8 16.8 5.6 8.8 22.4 8.7 13.4 10.5 14.7 8.1 6.8 16.0 17.7 10.9 9.0 8.1 6.8 5.7 5.6 5.0 6.9 11.1 7.9 14.5 6.9 12.7 8.9 18.9 8.8 8.5 4.3 5.2 7.4 4.4 5.3 5.0 7.4 2.2 3.9 5.5 3.7 4.6 4.7 3.8 5.2 4.3 15.7 20.1 20.7 16.8 14.1 16.2 15.9 15.7 17.1 15.4 17.9 6.4 18.7 28.1 36.1 36.0 49.4 12.7 6.7 7.9 22.7 19.6 28.8 58.0 26.3 26.2 18.6 15.4 0.0 19.8 19.5 23.5 31.2 4.7 21.3 16.6 22.3 13.3 23.9 33.0 39.2 20.8 22.4 27.0 14.4 23.7 22.1 21.3 24.6 23.7 44.0 19.0 32.3 22.7 60.0 42.9 27.0 28.3 34.8 27.1 23.7 RCL1 "RNAC, RPCL1" ENSG00000120158 "RNA terminal phosphate cyclase like 1" Q9Y2P8 9 4792869-4885917 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "liver: 108.1;pancreas: 37.5" "Cell type enhanced" "Detected in many" 9 "Hepatocytes: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HDLM-2: 35.1;HEL: 90.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071308 Approved Nucleoplasm NA NA Nucleoplasm "HPA071308: AB_2686384" "prognostic favorable (5.48e-4)" "unprognostic (7.60e-3)" "unprognostic (7.55e-2)" "unprognostic (4.19e-2)" "unprognostic (1.07e-2)" "unprognostic (3.29e-1)" "prognostic favorable (8.02e-4)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.59e-2)" "prognostic favorable (2.40e-7)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-1)" "unprognostic (3.66e-2)" 15.9 6.8 4.2 6.7 5.9 17.2 12.9 5.5 6.3 5.6 3.8 6.2 6.3 2.4 5.5 5.4 5.5 5.6 3.8 3.7 4.1 3.6 5.7 108.1 6.9 9.1 5.8 4.2 9.0 37.5 3.8 5.1 6.8 5.6 3.6 4.2 4.5 4.8 9.1 10.9 10.5 4.1 5.2 7.1 5.0 5.2 6.8 5.6 5.7 4.5 8.1 7.2 5.3 6.8 10.4 6.8 12.9 2.3 10.8 9.1 3.5 5.6 6.7 2.6 4.1 3.9 2.6 6.8 2.6 2.9 5.0 4.2 3.4 3.3 10.9 1.9 2.4 5.6 3.6 11.9 8.0 5.8 35.1 6.1 90.1 8.1 6.7 5.6 8.1 7.3 5.8 4.6 4.8 7.4 2.7 4.9 8.0 9.2 7.1 3.0 7.3 6.6 14.0 8.9 6.8 2.7 8.2 3.4 5.7 6.1 6.4 7.4 6.1 3.4 5.0 3.9 5.3 4.7 9.6 3.4 3.0 3.3 4.1 8.2 2.9 8.2 11.7 5.4 5.0 1.9 12.9 1.5 3.8 5.6 2.3 6.8 8.0 6.6 7.6 4.0 10.4 8.9 9.1 0.6 10.8 1.2 6.8 5.5 3.5 4.2 5.9 5.5 6.3 4.1 3.6 5.8 4.2 5.6 5.6 6.0 5.0 10.0 14.8 22.7 4.8 10.1 5.1 16.0 6.8 3.5 0.0 33.2 21.6 11.0 59.1 7.7 2.2 0.0 9.9 10.9 10.3 6.4 13.9 135.7 15.5 4.8 2.9 16.0 8.8 39.4 21.3 5.8 3.3 15.4 6.4 7.8 9.2 2.9 35.3 12.1 6.5 12.9 14.6 17.7 19.5 18.4 29.6 10.1 7.2 12.6 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621394-74666881 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol No No Nucleoplasm Cytosol "HPA048258: AB_2680332, HPA075649: AB_2686761" "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 7.3 5.2 4.2 12.2 6.1 33.9 7.8 7.8 5.6 7.4 6.7 8.4 8.4 5.5 9.7 10.0 12.8 6.3 5.5 5.4 3.9 3.7 6.5 5.6 6.5 12.0 6.1 4.8 7.7 9.6 8.5 7.5 11.5 5.3 6.5 8.1 7.2 8.0 8.4 4.5 11.6 7.8 5.6 4.8 9.7 6.2 35.1 7.2 40.5 7.0 7.5 18.0 7.2 8.6 9.3 7.1 13.8 10.9 9.1 11.7 6.5 14.1 18.2 13.8 10.0 2.9 4.0 15.5 12.8 9.9 20.5 17.9 23.7 14.9 19.8 10.5 10.0 10.3 17.1 22.4 13.3 25.2 6.2 13.4 17.5 14.8 13.3 2.5 17.6 18.3 2.8 4.2 25.8 16.0 5.3 8.7 16.9 26.4 8.9 15.4 22.6 25.6 16.1 27.1 8.3 8.8 39.9 9.3 17.4 7.3 15.1 10.2 10.9 20.6 7.3 9.1 13.0 13.4 15.0 8.4 15.0 14.4 8.4 16.1 12.1 22.4 59.4 10.7 13.6 18.2 13.8 6.8 9.9 9.3 6.3 10.2 7.8 7.7 8.6 7.1 9.3 11.7 8.1 7.7 9.1 10.9 5.5 10.9 6.5 4.2 6.1 7.8 5.6 3.9 3.7 6.1 4.8 5.3 7.2 0.0 5.1 11.2 5.0 9.6 5.8 2.4 2.5 2.7 5.7 1.8 9.8 9.1 10.0 5.6 4.2 5.2 4.2 23.3 6.6 6.6 4.8 9.2 4.6 6.4 7.6 3.2 9.1 10.4 13.7 5.4 3.4 6.1 15.1 3.6 8.3 3.5 8.2 0.0 3.9 3.4 6.8 6.5 5.6 46.5 30.6 8.2 6.3 7.5 7.3 12.0 RING1 RNF1 ENSG00000204227 "Ring finger protein 1" Q06587 6 33208495-33212722 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008701 Supported Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA008701: AB_1079814" "unprognostic (2.12e-3)" "unprognostic (7.98e-2)" "unprognostic (3.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.91e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-1)" "unprognostic (4.75e-2)" "unprognostic (7.76e-2)" "unprognostic (1.26e-2)" "unprognostic (3.70e-2)" "unprognostic (1.62e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.55e-1)" "unprognostic (2.13e-1)" "unprognostic (9.88e-2)" 26.7 22.6 17.8 15.9 21.3 12.0 14.6 27.6 24.2 22.2 17.6 22.0 21.0 18.2 31.9 17.3 14.5 18.8 21.4 14.4 17.3 18.2 19.3 21.6 16.8 14.5 24.0 15.4 25.0 18.3 24.0 34.0 14.9 17.0 21.8 7.6 20.0 19.0 20.5 18.0 21.7 19.5 22.9 18.5 23.2 24.1 16.9 20.8 25.5 29.3 13.1 14.3 13.9 17.1 1.2 2.2 0.8 1.5 0.2 2.2 0.2 4.2 3.6 4.2 4.1 4.3 1.4 9.8 11.2 6.8 4.6 4.7 3.8 3.2 7.0 4.7 4.5 5.8 7.7 3.6 3.4 3.2 8.6 2.9 8.4 5.9 7.2 9.7 4.8 6.9 0.0 3.4 4.1 7.6 3.6 1.7 3.8 12.1 5.4 4.8 0.0 0.3 3.7 1.9 3.1 4.6 4.5 7.0 7.7 5.0 3.7 8.4 5.2 4.0 4.3 11.6 1.1 5.0 8.4 2.3 5.1 3.8 0.0 9.2 6.1 6.2 6.7 3.8 4.4 3.1 0.0 1.5 0.8 2.2 0.4 0.4 1.1 0.7 1.0 0.7 1.2 1.7 0.9 0.3 0.2 0.5 2.2 0.4 0.2 17.8 21.3 27.6 24.2 17.3 18.2 24.0 15.4 17.0 20.8 0.0 22.7 20.1 35.5 24.5 30.5 21.4 17.8 17.4 14.8 21.0 15.7 36.0 13.3 28.6 21.1 23.2 23.3 0.0 30.3 27.6 28.0 27.3 19.6 30.5 26.3 23.8 29.4 30.7 29.6 13.2 37.2 20.0 16.9 20.8 19.8 38.3 26.5 21.0 28.0 26.9 18.0 25.8 22.7 32.9 18.8 26.7 52.7 25.4 21.0 24.7 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389496-7418037 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Supported Cytosol NA NA Cytosol "HPA017866: AB_2669670, HPA051446: AB_2681488" "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 13.8 10.6 7.7 13.2 13.0 17.5 13.1 12.2 13.5 12.7 11.6 7.3 4.0 7.3 15.4 6.0 15.6 12.3 8.5 11.8 8.0 8.1 8.7 11.7 10.1 14.2 11.6 9.4 13.8 15.3 7.7 17.8 13.9 13.3 10.7 9.6 7.2 10.2 10.3 18.8 12.5 9.9 15.5 9.4 14.4 10.3 21.3 9.2 19.2 10.1 14.7 16.8 10.9 12.6 15.4 14.9 7.7 11.1 18.6 15.0 8.2 7.6 4.4 7.2 16.8 11.2 9.2 11.0 9.6 6.5 9.0 7.4 12.9 3.9 19.9 17.1 7.8 7.8 7.8 18.1 7.7 11.5 13.1 19.5 10.6 7.1 13.8 9.5 30.5 13.9 6.8 10.7 9.7 20.0 4.3 7.9 15.0 27.0 4.7 8.4 10.0 20.7 14.5 15.4 14.2 10.5 15.9 9.4 21.6 5.0 7.4 24.0 11.8 8.1 4.9 14.0 19.4 7.4 10.1 7.9 9.8 7.4 6.5 14.5 6.4 12.2 29.6 3.0 15.7 15.0 7.7 8.5 5.9 11.5 11.1 13.8 15.2 11.9 12.1 14.9 15.4 13.7 15.0 1.7 18.6 9.7 12.4 11.3 8.2 7.7 13.0 12.2 13.5 8.0 8.1 11.6 9.4 13.3 9.2 6.0 26.6 22.4 26.7 46.9 9.2 20.4 2.5 25.4 45.5 7.0 9.8 29.8 3.3 13.2 34.2 23.9 5.8 0.0 10.2 28.8 22.0 11.9 32.4 8.9 20.4 4.8 6.9 17.2 6.5 6.5 18.4 16.7 16.9 11.8 10.4 5.5 10.9 5.8 18.7 9.0 10.4 19.4 26.4 55.6 78.8 56.7 23.3 22.0 15.3 20.6 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 22.2 20.1 14.8 17.1 17.5 24.4 19.7 26.3 18.6 19.1 17.0 8.9 14.0 17.3 17.5 17.1 17.0 15.0 10.7 19.6 15.7 13.4 21.0 23.6 13.3 17.6 20.0 11.1 20.7 21.5 15.1 37.5 15.8 19.7 19.5 17.3 10.3 18.7 16.6 24.9 13.3 20.2 16.3 20.7 22.5 16.4 14.8 18.6 25.8 21.7 20.7 17.4 20.7 21.0 15.2 17.8 9.4 18.7 17.8 24.1 13.5 8.8 10.4 9.7 18.8 12.8 14.0 15.5 22.3 13.8 15.8 21.0 14.2 15.6 19.6 25.4 10.0 24.9 10.5 16.5 13.0 21.7 13.8 9.1 9.8 20.1 19.8 11.5 18.6 13.8 9.2 10.2 19.3 19.6 12.1 12.8 14.6 14.8 12.7 18.1 14.8 21.8 22.3 11.5 5.3 11.2 24.5 18.9 28.8 12.4 8.1 12.1 9.0 13.5 14.1 15.4 15.1 14.7 17.8 13.7 20.3 14.1 16.1 24.3 12.5 16.2 44.0 12.1 19.1 18.5 7.0 16.0 9.4 16.3 18.7 22.3 15.2 20.7 17.8 17.8 11.0 22.5 24.1 3.2 17.8 13.4 17.8 18.5 13.5 14.8 17.5 26.3 18.6 15.7 13.4 20.0 11.1 19.7 18.6 8.9 10.9 13.0 14.3 23.5 16.4 15.9 12.7 10.7 11.4 7.0 11.8 16.7 14.9 14.2 1.1 14.0 7.0 0.0 13.1 19.4 15.8 9.9 27.6 7.8 15.9 12.7 9.2 6.2 11.0 1.8 12.4 11.5 5.0 13.6 11.2 12.3 10.5 10.5 15.2 12.2 17.2 6.5 21.7 20.7 20.2 16.6 14.5 14.4 12.1 11.4 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23452823-23486603 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.10e-4)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 10.1 8.7 6.9 11.7 7.7 52.4 10.9 8.9 10.1 14.7 21.4 8.5 5.9 15.6 8.8 9.3 41.0 7.8 10.7 11.5 6.1 5.5 10.5 19.9 10.1 10.7 9.1 6.2 7.6 10.7 7.5 11.6 21.4 11.6 6.8 14.7 6.0 14.9 7.0 40.0 13.3 36.5 15.2 10.5 8.9 12.9 22.7 7.6 11.1 7.3 16.0 16.5 13.7 21.5 11.7 11.0 21.7 21.5 8.3 11.2 10.0 14.8 5.8 6.1 7.9 11.1 12.4 11.0 14.9 11.0 10.6 10.2 6.7 16.1 10.3 19.6 16.6 10.8 19.5 10.3 17.0 16.4 10.2 4.3 9.6 10.9 8.4 27.8 27.0 8.4 14.8 32.4 18.8 26.0 12.1 14.7 6.5 13.9 13.0 15.9 7.9 9.3 4.4 5.6 21.7 11.7 10.5 12.7 12.5 12.1 19.5 14.2 10.2 19.1 8.7 10.9 15.9 7.7 14.6 23.1 17.5 4.4 7.7 9.6 23.5 19.7 15.3 10.3 12.5 13.1 21.7 13.5 8.0 9.1 19.6 6.9 8.2 7.6 7.9 11.0 11.7 6.1 6.9 9.3 8.3 21.5 5.1 11.2 10.0 6.9 7.7 8.9 10.1 6.1 5.5 9.1 6.2 11.6 7.6 74.5 51.9 21.7 78.2 107.0 43.0 61.7 43.3 56.2 67.1 24.4 53.0 38.5 21.6 40.3 191.3 39.6 193.3 116.8 45.8 56.7 46.6 92.4 61.2 72.5 37.1 27.0 60.3 33.7 55.0 227.3 20.8 49.5 40.5 47.7 85.9 17.1 98.8 75.8 28.3 40.3 43.8 6.5 38.7 23.6 9.5 125.6 73.9 34.1 42.3 194.9 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063991-3115187 "Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Supported "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favorable (6.71e-4)" 24.5 12.0 6.9 15.7 12.4 10.5 28.0 11.9 11.0 16.4 18.9 9.6 22.9 14.5 16.8 17.7 17.1 13.5 17.9 12.3 7.5 6.8 18.5 36.7 16.7 19.8 11.8 6.6 13.2 19.9 14.4 17.9 24.4 10.2 17.8 16.6 10.9 21.1 18.7 11.4 18.9 24.8 21.3 6.9 19.4 15.8 9.0 9.4 18.6 18.5 15.2 19.2 15.0 20.4 4.1 3.2 6.6 3.9 6.6 7.6 2.1 9.5 6.8 10.3 10.6 22.0 14.1 5.7 15.0 20.4 15.9 18.3 9.2 6.6 8.9 14.5 21.5 16.7 11.0 12.8 12.3 17.4 18.4 6.9 11.5 4.5 6.7 12.4 9.9 14.7 19.0 11.0 14.7 10.7 13.0 13.7 5.5 12.9 5.1 15.3 12.3 6.8 10.8 6.5 11.5 8.5 8.3 7.6 10.0 14.2 19.1 8.9 8.8 9.9 6.2 16.6 21.9 11.4 7.1 16.6 17.4 9.3 6.6 11.1 7.9 10.2 9.5 7.3 5.5 19.2 1.1 3.0 6.4 6.1 3.7 4.9 2.0 4.9 7.6 3.2 4.1 4.1 5.4 6.6 6.6 3.9 2.9 5.7 2.1 6.9 12.4 11.9 11.0 7.5 6.8 11.8 6.6 10.2 9.4 6.0 8.1 8.8 8.6 9.7 3.4 6.9 12.7 21.4 20.5 8.7 11.8 7.3 5.0 8.1 1.6 15.8 13.6 0.0 11.3 5.6 9.8 8.2 10.4 12.3 10.1 4.8 6.3 11.6 5.1 0.4 6.4 11.1 3.3 17.2 15.4 7.2 10.3 10.1 5.6 8.2 21.0 19.4 15.1 0.9 2.5 8.7 10.0 12.5 9.3 12.2 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757747-89791063 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol NA NA Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavorable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favorable (8.05e-4)" 12.0 5.5 9.3 11.2 7.9 13.6 10.0 3.0 9.3 9.7 7.9 10.6 5.2 3.5 10.9 7.8 8.3 7.0 17.3 11.6 9.2 8.6 7.7 10.4 18.7 10.9 11.8 5.8 8.9 13.2 14.7 7.3 20.8 9.1 10.7 5.6 4.6 10.2 5.8 3.1 10.4 6.9 10.4 16.5 14.2 8.3 5.6 11.5 5.1 8.5 4.9 11.8 15.0 7.6 7.5 6.9 19.4 11.2 3.8 5.5 4.3 10.3 3.6 1.8 2.6 4.5 6.3 3.4 11.5 19.6 6.1 7.9 3.1 5.4 8.0 17.9 6.4 4.9 2.5 4.9 3.8 11.3 5.7 4.9 6.7 1.7 3.1 12.7 2.4 3.3 5.0 3.1 8.7 28.1 6.5 6.4 0.0 3.2 2.6 5.6 2.1 0.0 5.1 1.0 4.7 8.5 1.7 2.6 3.9 14.3 4.6 0.3 2.0 2.7 7.2 5.4 2.5 7.0 3.0 5.7 3.7 3.5 6.3 5.3 5.3 2.4 4.8 9.1 0.2 2.4 8.8 5.7 19.4 3.6 10.6 4.1 7.5 5.5 4.7 6.9 4.3 5.2 5.5 4.5 3.8 11.2 2.3 1.2 4.3 9.3 7.9 3.0 7.4 9.2 8.6 11.8 5.8 9.1 11.5 32.8 17.8 13.4 31.1 51.2 2.4 2.8 5.1 10.7 22.7 3.5 0.0 10.6 5.0 66.4 5.0 9.5 2.3 0.0 53.1 35.2 38.5 46.3 42.7 2.6 39.0 3.2 0.0 5.5 25.3 1.6 7.2 48.6 18.6 50.5 5.2 10.0 41.2 0.0 5.6 6.7 0.1 12.9 22.7 8.1 10.9 42.2 70.0 12.7 6.6 40.4 RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336021-24340045 "Enzymes, Predicted intracellular proteins" "Apoptosis, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.8" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 20.6;Exocrine glandular cells: 30.8;Paneth cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.6;HDLM-2: 4.3;OE19: 11.3;SK-BR-3: 12.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" 7.6 1.3 1.8 9.7 2.4 4.3 6.0 0.9 1.6 4.5 13.6 1.8 1.4 10.6 3.7 3.8 9.2 3.2 12.7 2.6 2.7 0.6 3.8 1.3 6.4 7.2 3.9 0.8 1.7 8.4 0.5 0.9 3.7 2.3 3.7 11.8 3.6 7.5 1.7 2.1 5.9 25.8 2.1 3.8 15.1 9.2 1.6 3.6 7.2 8.7 6.1 13.3 4.6 5.6 3.5 5.2 6.3 8.8 3.9 9.1 4.3 0.0 0.0 0.0 0.0 2.9 3.2 0.0 0.7 3.9 0.0 0.0 0.1 7.6 0.1 2.0 0.3 0.0 1.9 0.0 0.1 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 0.0 0.5 0.0 11.3 0.0 0.0 0.0 1.3 1.4 0.0 0.0 0.0 0.0 12.5 0.0 0.0 2.2 3.3 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 2.6 5.1 6.3 6.3 7.7 6.4 3.5 5.4 6.2 5.2 3.5 2.9 4.0 2.6 3.9 8.8 2.6 9.1 4.3 1.8 2.4 0.9 1.6 2.7 0.6 3.9 0.8 2.3 3.6 3.0 10.8 1.9 1.6 1.3 0.0 0.4 2.5 1.4 1.2 3.5 0.0 0.3 3.3 6.3 0.1 2.9 20.6 0.0 30.8 0.2 1.8 0.6 11.6 0.0 11.0 0.0 5.8 0.0 10.0 0.0 0.0 6.3 3.3 10.8 9.2 0.0 15.3 17.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 1.3 0.2 8.7 6.5 2.3 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767106 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "naive CD4 T-cell: 1.5;neutrophil: 2.2" "Group enriched" "Detected in many" 17 "granulocytes: 2.2;T-cells: 1.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 15.9;GAMG: 20.8;HaCaT: 23.5;hTCEpi: 15.8;RPTEC TERT1: 14.2;RT4: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030942 Enhanced NA NA "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.0 0.2 0.2 0.8 0.2 0.1 3.3 0.2 0.2 6.7 9.4 0.3 12.0 6.8 1.7 6.5 42.1 4.2 17.1 1.1 0.4 0.2 10.8 17.3 5.4 0.4 0.2 0.1 1.8 14.4 4.7 6.8 2.8 1.1 10.6 1.3 4.8 10.2 14.8 0.2 11.7 11.6 2.0 0.3 0.2 11.2 2.7 0.0 8.1 13.6 12.3 26.6 5.2 11.0 0.0 0.0 2.2 0.1 0.0 1.5 0.2 6.8 4.4 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.1 11.4 15.9 0.0 6.7 1.4 20.8 23.5 0.3 9.5 0.0 0.0 4.7 0.0 3.3 4.2 0.0 0.0 0.0 0.0 15.8 0.1 2.1 0.0 0.0 7.1 0.0 0.0 0.0 5.0 0.9 0.0 0.4 4.5 13.1 0.0 0.0 1.1 14.2 15.1 2.3 0.1 7.7 7.8 7.1 0.7 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.1 1.1 0.0 26.8 10.8 0.0 26.1 14.1 0.0 1.0 12.7 17.4 14.8 3.5 0.0 7.0 8.3 10.8 0.4 0.0 17.3 0.0 9.0 4.7 0.7 20.1 2.3 16.1 0.9 0.0 21.8 0.0 1.6 1.1 0.0 0.6 6.8 0.0 13.4 0.0 14.2 8.7 0.0 10.0 0.9 0.0 0.3 1.1 0.6 13.2 2.1 0.0 9.8 19.5 RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603393-86623866 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 9.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved NA NA "HPA057922: AB_2683555" "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favorable (6.77e-5)" 13.2 13.5 18.0 9.8 20.6 9.8 18.5 38.3 24.6 15.8 28.1 16.9 9.6 15.6 18.8 39.7 11.7 12.7 23.3 29.5 16.7 15.9 13.1 43.8 8.6 8.5 17.8 10.6 13.2 20.2 23.8 12.2 16.2 14.7 20.5 14.2 14.5 13.8 16.1 17.7 10.4 27.2 17.9 21.8 8.1 18.7 13.7 16.5 11.9 9.0 8.8 8.3 13.4 11.5 1.4 1.6 9.9 0.9 3.0 3.4 0.9 5.6 7.7 3.9 6.0 18.0 11.7 6.4 8.1 12.5 4.2 5.7 4.4 9.7 9.4 9.9 12.2 15.3 6.9 5.2 6.4 6.4 7.8 7.1 5.3 3.5 9.8 17.1 1.8 8.0 17.0 13.5 6.2 7.8 15.1 12.6 4.5 1.9 5.7 11.5 6.9 4.0 4.7 1.8 11.2 5.5 2.5 16.9 5.5 15.4 8.9 6.2 6.4 9.6 21.5 8.0 5.2 8.2 4.4 14.2 8.2 3.9 8.2 4.8 19.9 6.6 6.3 6.5 3.0 3.9 6.5 0.7 9.9 1.1 0.9 1.5 1.4 1.6 2.4 1.6 1.4 1.9 1.3 1.5 3.0 0.6 1.0 3.4 0.9 18.0 20.6 38.3 24.6 16.7 15.9 17.8 10.6 14.7 16.5 8.9 12.6 8.5 27.7 42.8 14.8 30.8 22.9 17.4 15.9 19.2 3.9 10.6 1.7 14.0 14.5 16.6 43.9 23.3 24.9 6.3 29.6 44.0 18.4 58.4 8.3 17.5 30.5 23.4 11.8 7.0 23.6 10.6 10.1 2.8 35.6 17.5 25.0 38.6 21.5 12.8 8.8 6.5 25.8 21.5 13.0 38.6 34.2 6.4 20.1 37.4 RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824077 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria NA NA "Nucleoli, Mitochondria" "HPA019130: AB_1859220" "unprognostic (3.44e-2)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (2.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" "unprognostic (3.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" 7.2 5.2 6.8 4.8 6.8 6.4 7.7 16.2 7.0 6.3 3.4 4.6 5.7 3.5 8.9 5.0 5.8 4.3 4.8 23.5 5.8 5.6 5.1 3.9 5.6 4.7 6.2 4.7 4.5 5.8 5.9 3.5 5.2 6.5 3.8 7.3 3.6 5.6 27.6 3.8 3.1 10.9 4.5 4.2 3.8 3.4 4.5 6.0 5.0 5.4 4.5 4.1 6.3 2.7 2.4 9.0 2.2 3.2 3.2 1.4 11.3 4.7 5.8 4.3 10.7 14.0 4.7 8.6 16.0 6.4 7.8 5.1 4.1 8.0 9.8 12.2 6.3 8.0 6.4 5.9 6.9 8.0 4.2 6.4 6.1 4.7 6.7 9.9 14.8 8.1 5.2 6.4 7.8 7.3 8.1 6.3 6.3 13.1 11.5 8.6 7.2 6.3 7.3 7.2 10.0 7.0 5.8 6.6 12.4 3.8 5.9 8.1 7.0 8.6 6.4 7.5 9.5 9.5 10.0 9.3 7.3 5.6 9.1 11.0 10.4 8.4 4.7 6.7 5.9 9.0 2.2 3.2 3.2 1.5 2.7 2.7 2.2 3.2 1.8 2.4 2.3 3.1 1.7 3.2 1.6 2.4 2.0 1.4 14.9 29.8 29.4 28.9 18.3 96.0 134.9 25.5 24.1 26.1 17.4 108.0 23.1 28.2 34.8 52.4 66.1 14.0 23.3 69.3 24.5 48.2 51.0 31.1 28.7 32.3 77.9 26.0 66.3 32.6 18.4 36.5 29.9 37.1 88.4 19.7 66.7 49.7 20.9 76.0 37.2 104.3 58.2 49.2 78.7 54.1 15.7 16.6 66.0 23.8 32.8 RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689499-49721529 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Supported Approved Cytosol NA NA Cytosol "HPA065983: AB_2685592, HPA071879: AB_2686468" "unprognostic (2.68e-1)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (9.51e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (5.03e-3)" "prognostic favorable (1.33e-8)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-2)" "unprognostic (3.83e-1)" 5.3 8.0 7.7 8.0 10.4 17.5 5.0 13.8 13.6 5.2 6.8 6.2 7.8 12.7 6.4 8.0 7.5 6.4 7.0 12.9 8.5 6.8 8.4 21.8 5.7 6.1 7.3 6.6 5.1 7.7 8.9 8.4 7.3 6.6 7.3 4.8 7.6 6.9 6.7 81.2 7.7 12.5 6.2 6.7 7.6 6.9 8.8 7.8 8.3 6.2 12.0 9.1 6.6 4.8 11.3 12.7 11.8 10.9 7.7 11.4 5.3 6.7 9.6 11.4 11.8 17.4 10.8 12.3 8.8 11.7 11.3 12.6 10.2 11.7 16.5 8.1 12.6 10.0 8.5 8.6 13.3 7.9 10.9 11.8 13.4 18.9 22.3 17.4 13.0 14.6 13.6 13.1 10.6 12.3 11.2 11.6 16.8 14.1 14.3 9.5 10.1 13.7 21.1 6.3 8.5 15.5 6.5 7.0 17.0 15.4 11.5 7.8 15.7 12.2 10.8 13.4 6.7 11.1 23.4 12.0 9.9 12.1 8.9 10.9 19.5 19.1 6.6 14.1 16.5 14.9 11.8 10.9 7.9 11.4 9.5 6.8 9.8 7.2 6.8 8.6 11.3 8.7 8.2 6.3 7.7 9.7 12.7 5.5 5.3 7.7 10.4 13.8 13.6 8.5 6.8 7.3 6.6 6.6 7.8 8.9 4.0 4.4 2.4 2.1 8.6 1.0 20.4 1.4 4.5 3.5 3.9 5.6 5.0 4.9 10.6 3.6 13.1 0.0 4.8 3.6 4.9 4.4 6.9 23.8 4.8 6.4 6.4 9.8 9.9 12.6 6.9 3.2 3.3 4.6 5.9 3.5 6.0 7.0 5.3 8.5 8.2 0.0 4.9 8.7 9.1 2.6 7.1 2.9 6.3 3.7 RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018372-32073213 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 67.5;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "HMC-1: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Golgi apparatus" Nucleoli "HPA041514: AB_10795596" "unprognostic (2.13e-2)" "unprognostic (2.05e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-1)" "unprognostic (5.03e-1)" "unprognostic (4.50e-2)" "unprognostic (2.30e-3)" "unprognostic (6.15e-2)" "unprognostic (4.21e-2)" "unprognostic (3.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (2.99e-1)" "unprognostic (4.12e-1)" "unprognostic (1.82e-1)" "unprognostic (7.07e-3)" 21.9 2.3 4.1 9.1 5.7 18.2 20.4 1.2 6.6 5.0 8.9 12.2 3.3 12.3 7.2 5.5 3.9 4.3 6.0 5.4 6.1 4.1 2.1 14.1 10.3 13.5 7.7 3.1 2.4 4.2 2.5 1.3 4.4 7.0 3.1 7.8 1.6 5.0 1.9 4.4 6.0 26.0 4.1 12.0 7.4 4.2 3.3 8.3 14.8 3.2 2.9 7.2 4.5 6.2 2.1 3.4 9.0 3.8 11.7 12.5 5.1 0.7 0.1 0.1 0.2 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 0.2 0.5 0.9 0.8 0.1 4.0 1.6 0.2 0.2 0.2 0.1 5.2 32.5 1.0 1.5 0.0 1.8 0.2 0.3 1.6 0.1 1.2 0.0 1.2 1.3 4.9 2.6 5.3 0.9 5.5 0.4 0.1 0.3 0.3 0.5 0.2 0.1 0.1 8.0 1.1 0.8 2.5 0.1 0.1 0.5 0.1 0.0 3.8 0.1 0.1 0.4 7.0 4.2 9.0 3.8 3.3 12.5 2.0 8.2 2.0 10.1 10.5 3.4 2.1 8.2 10.6 1.5 11.7 1.9 3.4 10.0 5.1 4.1 5.7 1.2 6.6 6.1 4.1 7.7 3.1 7.0 8.3 3.0 8.0 9.9 2.9 8.8 0.4 1.4 2.5 2.7 5.7 12.2 0.0 0.3 1.7 0.8 67.5 23.2 25.5 0.0 1.6 0.1 1.9 2.4 17.4 15.5 8.9 0.0 1.2 6.7 14.8 11.5 2.6 13.9 1.7 1.0 8.2 1.2 1.3 0.0 0.0 1.1 0.6 0.0 1.9 0.5 0.7 5.9 0.7 66.0 13.6 2.1 RNF126 FLJ20552 ENSG00000070423 "Ring finger protein 126" Q9BV68 19 647526-663277 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043050 Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA043050: AB_10794768" "unprognostic (2.24e-1)" "unprognostic (1.64e-1)" "unprognostic (1.97e-1)" "unprognostic (2.48e-3)" "unprognostic (1.90e-1)" "unprognostic (2.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (9.96e-3)" "unprognostic (7.04e-3)" "unprognostic (3.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" 14.2 14.2 13.4 17.0 13.7 18.7 14.5 12.2 24.7 9.8 16.0 14.8 7.4 24.3 10.4 9.2 19.8 9.5 13.1 14.2 13.1 10.2 11.6 27.9 10.4 19.9 11.4 11.6 12.1 22.4 5.9 10.0 14.1 12.3 10.0 6.3 10.1 13.2 9.3 50.3 21.9 20.3 9.9 10.0 18.6 21.0 33.6 9.3 16.1 8.6 19.5 18.6 13.1 11.2 15.9 13.6 7.5 13.8 17.1 17.3 9.2 25.9 8.6 7.3 10.3 1.7 2.4 12.5 13.6 5.2 7.9 7.5 17.4 9.1 21.5 8.9 5.7 3.1 17.4 4.4 10.2 2.2 14.2 31.8 10.9 9.0 14.4 6.6 21.6 16.1 4.1 8.1 6.5 5.1 3.2 7.2 17.7 21.9 21.7 4.1 20.9 22.1 10.1 19.5 5.5 17.0 16.1 6.3 33.8 6.0 14.5 17.4 13.6 10.3 13.6 13.9 2.6 8.7 17.0 9.4 14.4 10.4 21.1 23.3 38.3 19.0 25.2 18.3 12.7 14.8 0.6 9.8 7.5 17.3 11.5 14.2 15.9 15.7 16.7 12.4 15.6 12.2 11.4 2.2 17.1 13.8 13.6 16.8 9.2 13.4 13.7 12.2 24.7 13.1 10.2 11.4 11.6 12.3 9.3 11.9 6.1 54.8 41.2 122.5 31.3 24.2 15.3 12.0 10.3 8.7 15.7 58.6 46.4 55.4 113.7 26.1 51.9 0.0 66.1 118.3 35.3 49.3 14.9 20.2 38.3 30.2 20.8 20.3 27.6 18.2 19.8 38.3 40.5 56.9 34.2 27.0 95.1 54.9 18.4 25.6 22.0 58.2 45.0 118.2 66.8 126.6 73.7 55.3 49.7 76.9 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128, E3 ubiquitin protein ligase" Q8TEB7 X 106693794-106796993 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.6;liver: 48.4;thyroid gland: 38.4" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 1: 62.5;Cholangiocytes: 61.1;Enterocytes: 52.7;Hepatocytes: 73.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 16.5;CAPAN-2: 13.6;Hep G2: 11.6;OE19: 36.6;RPTEC TERT1: 12.0;RT4: 34.2;WM-115: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "HPA019675: AB_2670225" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 1.4 20.6 2.4 2.2 7.2 0.0 3.0 0.7 4.2 0.5 24.4 0.9 0.4 24.2 0.2 2.2 4.0 0.3 27.2 0.6 2.8 5.1 24.4 48.4 6.7 0.0 2.4 2.1 0.7 14.5 0.0 11.0 10.5 4.0 3.4 7.8 0.0 25.4 0.8 3.0 3.6 54.6 0.9 1.1 0.2 17.9 0.3 1.0 1.1 38.4 2.3 2.7 10.2 3.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 4.1 0.0 0.0 0.0 1.4 0.7 16.5 0.0 0.1 0.0 0.0 7.2 13.6 0.0 0.0 0.2 0.1 5.1 0.0 0.0 0.0 0.0 8.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 36.6 0.1 0.0 0.0 0.0 12.0 34.2 0.0 0.0 0.0 0.9 0.8 0.1 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 7.2 0.7 4.2 2.8 5.1 2.4 2.1 4.0 1.0 62.5 15.8 0.0 5.7 6.1 0.0 0.5 61.1 9.4 20.5 31.4 0.0 18.2 0.0 9.8 0.0 0.1 52.7 0.0 13.5 2.1 0.4 1.8 0.0 73.1 1.6 0.0 23.8 0.6 3.8 0.0 0.0 0.2 3.3 0.0 36.5 0.0 21.8 22.4 0.0 21.1 0.0 0.0 0.2 0.0 2.2 4.5 13.8 0.0 23.4 7.4 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812708-149962139 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 72.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 24.0 21.3 30.6 19.0 39.4 9.8 28.5 19.9 30.4 19.0 17.7 39.9 16.2 14.3 16.8 33.7 16.8 15.9 20.4 16.4 40.5 29.7 35.8 39.2 31.7 19.6 60.9 26.8 18.1 19.6 23.5 14.9 32.4 40.7 25.5 20.3 19.5 36.1 20.9 18.0 18.4 16.3 20.4 102.2 25.5 17.0 12.5 51.2 13.3 32.1 18.8 15.9 21.4 16.5 8.8 15.7 72.4 31.5 7.8 8.5 14.6 19.7 12.3 8.3 9.5 32.8 20.1 13.9 10.9 28.2 10.6 15.8 10.8 28.4 8.2 16.0 13.4 19.5 18.8 11.1 14.0 14.9 10.0 8.1 9.9 5.7 10.5 21.8 10.6 14.1 21.2 26.6 8.9 24.2 12.8 11.7 7.9 3.1 16.7 9.4 11.1 7.6 7.0 5.5 19.1 9.6 5.5 8.9 34.8 20.5 9.2 4.4 12.7 9.0 13.6 35.2 6.8 25.9 11.2 12.2 14.4 5.8 15.2 7.0 28.4 18.7 16.9 12.1 9.9 7.7 12.9 20.3 16.6 6.8 25.2 8.5 8.8 7.6 7.6 15.7 8.3 7.3 7.5 72.4 7.8 31.5 11.2 8.3 14.6 30.6 39.4 19.9 29.2 40.5 29.7 60.9 26.8 40.7 51.2 101.3 59.5 39.3 61.2 65.4 43.7 25.6 38.2 34.8 61.4 45.4 27.5 86.4 36.5 54.3 2.2 62.6 27.6 0.0 62.0 65.2 68.3 63.5 58.9 46.6 172.6 20.6 19.4 77.3 168.9 4.7 70.5 155.4 97.8 42.3 26.4 85.9 48.5 29.6 82.7 59.8 32.2 90.5 50.9 19.7 29.6 63.2 43.8 51.0 24.3 45.5 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072118 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Hofbauer cells: 270.4;Kupffer cells: 303.4;Macrophages: 212.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 17.0;classical monocyte: 38.1;eosinophil: 24.6;intermediate monocyte: 27.5;myeloid DC: 31.1;neutrophil: 68.1;non-classical monocyte: 23.8;plasmacytoid DC: 22.9" "Group enriched" "Detected in all" 11 "dendritic cells: 31.1;granulocytes: 68.1;monocytes: 38.1" "Cell line enhanced" "Detected in many" "HMC-1: 41.5" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favorable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 36.3 16.3 23.5 16.3 32.5 29.5 24.0 19.0 25.3 26.0 16.7 56.0 19.0 10.6 18.5 12.0 10.6 19.5 21.9 17.0 27.8 21.1 20.7 64.4 25.5 19.1 50.2 20.3 21.7 28.6 11.0 16.7 19.8 30.3 16.3 16.1 15.8 30.6 28.3 17.3 7.9 12.1 22.2 58.2 20.4 20.5 7.3 38.8 2.5 14.3 6.3 10.3 20.7 13.3 1.2 31.1 68.1 38.1 4.0 2.0 20.3 8.0 5.9 29.0 21.2 28.3 15.4 5.5 6.3 7.9 6.9 7.5 1.9 6.9 0.0 19.5 11.0 12.3 0.8 20.1 12.8 7.6 0.1 17.9 15.9 3.2 4.1 7.2 3.8 41.5 14.5 6.8 0.5 3.9 17.4 11.2 16.4 3.2 0.1 6.9 12.2 7.2 12.3 7.9 1.5 9.0 16.2 6.7 0.0 8.7 1.4 17.6 7.9 11.7 6.4 24.3 12.3 9.2 9.1 8.7 11.7 4.7 8.2 6.7 0.0 6.2 1.6 1.5 30.5 9.1 17.0 38.1 24.6 2.0 27.5 1.9 1.2 0.9 1.0 31.1 1.2 1.0 1.2 68.1 4.0 23.8 22.9 0.1 20.3 23.5 32.5 19.0 25.3 27.8 21.1 50.2 20.3 30.3 38.8 17.9 25.0 20.3 17.8 12.6 26.9 27.4 73.9 65.6 22.7 40.1 49.1 10.0 19.9 43.4 9.6 42.9 21.0 0.0 67.5 13.5 39.8 43.3 79.8 129.2 270.4 6.4 15.6 43.0 303.4 14.4 33.9 212.8 30.4 45.1 37.0 18.1 46.5 35.1 45.3 34.2 17.7 45.3 40.1 8.6 27.9 11.3 7.3 17.3 61.0 17.1 RNF133 ENSG00000188050 "Ring finger protein 133" Q8WVZ7 7 122697712-122699156 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 28.3" "Group enriched" "Detected in some" 104 "Early spermatids: 461.8;Late spermatids: 540.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 4.1;MCF7: 1.5;NTERA-2: 1.2;PC-3: 1.1;U-266/70: 1.1" "Not detected" "Not detected" NA NA "unprognostic (2.82e-1)" "unprognostic (2.52e-2)" "unprognostic (1.77e-1)" "unprognostic (3.04e-2)" "unprognostic (2.45e-3)" "unprognostic (1.67e-1)" "unprognostic (8.87e-3)" "unprognostic (3.56e-2)" "unprognostic (3.72e-1)" "unprognostic (3.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.02e-2)" "unprognostic (7.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.39e-1)" "unprognostic (2.37e-2)" "unprognostic (7.61e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.3 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 4.1 0.0 1.5 0.0 0.0 1.2 0.5 1.1 0.0 0.0 0.8 0.0 0.4 0.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 461.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 540.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 4.8 1.5 0.0 0.0 0.0 0.0 0.0 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091855-32131561 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 43.8;bone marrow: 40.4;lymphoid tissue: 28.3;testis: 73.4" "Group enriched" "Detected in many" 16 "Early spermatids: 845.1;Late spermatids: 2984.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria NA NA Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 8.2 5.0 6.5 11.0 7.4 40.4 7.7 9.9 7.1 6.5 11.0 9.0 5.8 8.0 7.5 6.3 7.4 9.7 7.1 5.0 6.8 6.4 5.9 10.1 7.6 17.9 10.6 6.3 9.0 7.8 5.6 8.7 7.2 6.7 6.5 10.0 4.5 6.9 4.9 5.1 5.6 11.2 5.6 9.1 14.3 6.6 73.4 8.1 28.3 7.0 5.7 9.9 6.1 6.8 14.4 24.3 25.7 24.9 16.4 43.8 24.2 9.1 5.4 22.4 11.1 2.9 6.1 12.7 9.3 5.3 11.7 13.6 6.4 6.4 22.0 11.7 6.1 7.6 9.5 11.7 10.5 16.0 12.2 19.6 17.3 7.0 7.8 11.5 47.6 15.4 5.9 10.6 12.9 18.4 6.8 11.9 19.7 23.8 9.0 7.5 8.7 32.1 21.3 25.0 15.8 7.5 33.2 14.1 12.6 10.7 6.8 25.4 12.7 12.5 7.2 9.7 10.7 4.7 20.1 9.1 14.1 10.3 3.4 10.4 15.0 19.9 38.1 7.7 26.6 13.8 8.0 24.9 24.0 10.5 18.6 13.4 14.0 22.9 14.8 24.3 14.4 43.8 27.9 25.7 16.4 15.3 10.5 16.7 24.2 6.5 7.4 9.9 7.1 6.8 6.4 10.6 6.3 6.7 8.1 14.9 22.4 13.8 29.1 61.6 6.1 6.7 25.5 16.0 18.2 15.7 0.0 25.9 14.9 15.3 845.1 21.2 16.7 0.0 16.0 16.6 21.4 26.1 22.0 14.7 21.1 7.9 28.7 20.3 27.6 2984.7 27.3 30.7 25.3 10.8 21.0 8.0 10.5 20.1 20.8 10.7 4.8 32.3 25.9 118.9 102.4 45.7 7.4 27.7 27.0 31.8 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474738-124487914 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Early spermatids: 763.4;Late spermatids: 690.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved NA NA "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 15.1 17.3 10.4 9.5 12.2 54.5 13.4 12.0 17.1 14.2 10.9 14.0 9.4 6.2 15.3 10.0 12.2 14.2 11.0 11.4 10.4 10.8 11.4 17.7 11.3 14.2 12.4 11.5 17.1 10.3 7.6 10.6 18.4 9.9 12.8 10.4 10.2 10.3 10.5 15.2 12.6 11.3 14.2 12.2 11.8 11.2 60.3 13.3 16.8 11.2 9.6 10.4 14.8 10.7 9.2 9.4 11.8 11.7 8.6 13.9 8.0 13.2 8.9 10.7 10.5 23.6 18.8 8.8 11.9 22.7 10.0 13.0 5.7 11.1 13.7 14.0 15.4 7.2 9.8 9.1 14.6 15.0 19.0 11.5 20.4 5.9 11.8 18.0 9.6 11.8 16.1 21.2 10.6 28.8 13.7 13.4 12.7 14.3 21.1 11.8 35.9 16.2 6.9 7.5 26.6 12.6 6.5 7.9 13.7 18.8 17.0 4.5 11.7 15.5 39.0 16.8 8.4 18.7 10.5 10.5 6.7 15.5 11.3 13.3 17.1 18.2 12.4 10.5 16.3 6.7 3.3 7.4 11.8 11.6 4.7 13.9 9.2 10.8 13.2 9.4 8.5 10.8 11.3 10.8 8.6 11.7 5.1 13.2 8.0 10.4 12.2 12.0 17.1 10.4 10.8 12.4 11.5 9.9 13.3 3.0 6.7 27.4 55.8 58.7 13.6 14.1 33.1 5.3 5.7 21.0 5.9 34.4 10.0 17.2 763.4 21.8 13.6 0.0 15.7 43.0 28.5 26.2 20.7 28.2 22.9 15.9 20.8 16.0 27.6 690.0 27.3 26.6 33.7 19.0 17.2 19.8 18.3 7.0 25.5 12.9 22.3 19.4 53.6 37.9 24.2 61.6 63.2 26.2 16.8 48.5 RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990291 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Early spermatids: 162.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008716, HPA064746" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA008716: AB_1856337, HPA064746: " "unprognostic (7.45e-3)" "unprognostic (1.38e-1)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.22e-2)" "unprognostic (7.42e-2)" "unprognostic (7.92e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.71e-4)" "unprognostic (6.89e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.06e-2)" 21.2 29.5 23.7 11.2 33.9 7.8 22.0 22.5 40.2 18.4 18.7 26.2 16.0 15.3 21.0 21.5 15.6 14.3 15.4 32.9 23.6 24.7 31.3 31.3 13.8 13.3 28.9 17.3 15.9 17.1 26.3 28.8 23.6 47.7 21.6 19.8 20.9 18.1 20.1 27.7 11.9 20.9 20.5 26.3 13.8 15.7 33.7 15.0 16.2 26.3 13.3 14.9 16.7 14.0 12.3 17.1 32.6 18.8 16.8 17.0 12.2 12.7 21.4 15.0 29.5 27.1 28.4 10.1 26.3 14.7 18.5 20.5 17.7 14.9 22.6 30.8 26.9 27.9 7.0 19.1 25.8 16.6 17.0 16.5 14.4 11.2 8.0 29.8 15.7 12.9 21.3 22.8 24.6 30.9 16.1 22.9 15.8 17.4 31.6 37.8 15.2 15.2 5.0 6.3 15.6 24.4 10.1 16.7 24.5 25.4 22.2 16.6 13.5 23.0 42.2 44.6 17.6 29.3 12.3 23.6 24.6 7.9 11.6 24.9 19.9 23.2 20.7 21.1 19.3 30.3 32.6 13.4 13.0 17.0 15.8 16.5 12.3 15.0 16.9 16.2 10.6 11.5 16.7 3.3 16.8 18.8 17.1 16.7 12.2 23.7 33.9 22.5 40.2 23.6 24.7 28.9 17.3 47.7 15.0 8.9 22.9 9.0 14.0 9.5 20.9 36.8 7.6 13.4 13.6 21.0 15.7 24.8 58.0 23.0 162.7 16.9 20.2 23.3 21.8 21.4 16.2 17.2 21.9 29.6 21.4 22.3 14.5 17.8 25.5 22.0 17.8 19.3 30.4 10.8 14.1 20.6 22.7 11.5 31.5 34.8 14.6 38.8 25.8 42.6 27.1 9.3 50.6 17.5 13.3 12.7 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917392-7068286 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" 9 "Cone photoreceptor cells: 70.7;Rod photoreceptor cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Group enriched" "Detected in many" 7 "granulocytes: 8.7;T-cells: 4.1" "Cell line enhanced" "Detected in many" "HEL: 15.2;HMC-1: 51.6;SH-SY5Y: 15.7;SK-MEL-30: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA Vesicles "HPA049939: AB_2680960" "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavorable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favorable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 12.9 28.8 13.3 4.2 21.2 12.1 11.1 45.5 20.7 17.3 5.2 28.7 9.0 3.0 26.0 8.3 4.7 8.4 7.5 8.0 15.6 11.6 7.5 1.8 5.7 7.9 26.5 12.2 20.0 29.7 21.5 12.5 6.2 13.2 8.7 5.7 5.9 4.0 7.4 8.7 5.7 4.1 12.2 21.8 21.1 2.8 5.0 27.1 3.4 3.2 1.2 5.8 5.8 6.5 0.1 0.2 8.7 0.1 0.8 4.1 0.6 0.3 2.2 12.0 2.4 2.7 5.6 9.2 0.0 0.0 0.4 1.1 0.0 0.2 1.1 1.3 0.1 3.5 0.2 3.9 0.0 0.0 0.6 1.0 15.2 0.1 4.5 0.1 0.3 51.6 8.9 0.0 0.8 0.0 0.0 0.0 3.9 6.5 0.2 0.0 1.9 7.8 0.6 4.4 0.3 5.4 6.1 8.7 1.0 0.4 3.9 3.9 15.7 0.2 1.6 15.4 1.6 0.7 1.0 0.0 1.6 4.1 4.2 1.7 4.1 1.3 0.0 6.0 3.4 5.6 1.5 0.1 8.7 2.1 0.0 3.0 0.1 2.1 1.5 0.2 0.1 4.1 2.8 0.4 0.8 0.0 0.0 0.8 0.6 13.3 21.2 45.5 20.3 15.6 11.6 26.5 12.2 13.2 27.1 3.0 3.4 0.5 0.7 2.2 3.6 10.6 2.5 2.7 3.4 0.0 70.7 1.7 1.7 2.7 5.7 7.0 4.2 23.3 5.0 2.7 5.3 3.5 9.2 0.8 3.8 9.5 24.5 28.3 1.0 10.4 4.0 1.0 23.6 1.0 2.5 7.2 4.5 9.1 9.9 0.0 42.2 0.0 3.8 1.6 6.0 1.4 0.9 6.4 2.9 0.2 RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468874 "Enzymes, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Basal keratinocytes: 563.5;Suprabasal keratinocytes: 1312.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 28.8" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;granulocytes: 15.6;monocytes: 28.8" "Cell line enhanced" "Detected in many" "Daudi: 55.9;EFO-21: 15.4;hTCEpi: 17.8;HUVEC TERT2: 16.5;TIME: 16.5;U-698: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria NA NA Nucleoli Mitochondria "CAB046013: AB_11126028, HPA054127: AB_2682391, HPA072469: " "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (4.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.48e-3)" "unprognostic (5.89e-2)" "unprognostic (1.18e-2)" "unprognostic (6.55e-2)" "unprognostic (2.87e-3)" "unprognostic (2.44e-2)" "unprognostic (2.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" 16.3 2.0 4.6 11.1 6.8 15.7 21.1 5.1 7.5 8.0 4.2 2.8 4.6 1.5 6.8 7.5 9.4 9.0 6.8 8.7 5.3 4.3 13.8 11.4 39.0 11.1 8.3 2.3 4.2 3.7 3.0 2.3 11.1 8.8 12.8 2.3 8.3 16.9 6.2 36.8 19.2 3.7 4.9 9.2 37.1 4.3 3.3 6.9 5.8 32.9 11.4 12.2 7.3 6.6 2.0 7.9 15.6 28.8 0.2 0.7 2.6 1.3 0.2 0.1 0.0 0.0 0.6 2.9 1.5 1.7 3.3 3.6 0.0 0.1 55.9 15.4 0.6 0.2 4.8 0.0 4.7 4.7 0.2 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.8 17.8 1.3 4.0 1.5 16.5 1.2 0.0 0.0 0.8 0.5 0.4 0.0 0.5 0.1 0.3 0.2 0.5 3.3 10.0 3.1 0.5 0.0 0.3 7.1 5.3 0.4 8.4 0.1 16.5 2.6 0.5 0.2 0.3 0.0 0.0 47.0 0.3 0.1 0.2 0.1 9.1 5.1 0.2 16.4 0.7 2.0 0.3 0.3 5.6 1.6 0.7 0.4 15.6 0.2 28.8 7.9 0.2 2.6 4.6 6.8 5.1 7.5 5.3 4.3 8.3 2.3 8.8 6.9 41.7 12.9 4.2 36.0 563.5 0.9 10.4 10.2 21.4 36.4 36.6 2.0 9.7 16.6 8.2 1.6 32.1 1.0 0.0 7.7 2.9 12.4 85.1 3.5 17.4 13.8 0.0 1.2 28.8 98.2 1.6 1.1 68.0 57.3 44.1 1.3 16.0 6.0 2.9 2.8 16.3 1.0 0.0 10.1 1.7 2.6 1312.2 1.3 3.2 2.4 20.3 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266610-127288567 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favorable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favorable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 27.3 20.9 28.5 16.6 29.1 5.1 23.9 63.7 34.5 22.7 18.6 29.2 10.5 11.8 32.0 35.2 14.2 17.9 21.3 25.2 26.3 21.7 20.9 16.8 21.0 17.3 30.0 27.7 28.5 12.6 26.5 27.4 27.8 31.3 18.6 17.6 17.5 16.7 20.3 55.9 16.0 15.2 26.1 28.7 24.6 15.5 16.3 27.7 9.2 26.7 15.5 17.6 19.2 18.7 11.7 14.2 22.8 22.8 11.5 10.3 9.1 5.5 7.0 26.7 23.5 24.8 24.9 9.7 18.9 30.3 10.1 14.6 9.1 8.4 10.0 13.4 15.4 15.9 7.1 7.9 8.9 14.8 11.5 6.9 12.7 8.4 12.7 24.6 7.5 9.1 21.7 18.7 11.4 22.8 23.4 17.7 10.0 13.7 9.9 22.3 10.6 7.4 13.6 9.7 3.4 7.3 9.4 6.9 5.0 14.4 6.1 16.0 16.2 7.4 10.5 11.6 16.5 7.1 26.1 20.8 17.9 5.9 18.5 13.3 14.3 8.8 6.6 13.7 13.2 16.8 16.8 18.9 16.1 9.3 20.0 9.7 11.1 8.0 10.3 14.2 11.7 7.3 10.2 22.8 11.5 22.8 7.1 8.6 9.1 28.5 29.1 63.7 34.5 26.3 21.7 30.0 27.7 31.3 27.7 32.8 24.8 20.8 11.4 15.8 34.0 33.0 38.2 20.1 7.9 8.7 3.9 25.1 34.9 24.3 40.1 34.9 12.8 0.0 14.1 22.7 38.1 21.4 21.9 25.2 22.8 28.6 19.7 28.3 67.8 33.7 64.5 25.0 43.9 24.4 11.5 36.1 15.1 13.9 62.6 42.1 18.1 32.3 33.5 44.7 12.2 17.6 32.2 28.7 10.9 14.1 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 123.7" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 255.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 123.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 123.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" 20.3 13.4 7.9 29.0 10.9 32.9 13.5 7.9 10.8 12.5 16.6 10.8 11.4 12.3 11.3 12.8 28.9 14.3 14.5 12.1 9.5 9.4 15.1 19.6 24.5 47.4 13.7 6.2 14.3 21.1 14.3 10.6 19.4 11.2 11.1 12.0 12.8 15.8 8.1 8.8 20.2 16.8 9.6 13.9 65.0 13.8 15.2 9.7 17.0 12.7 13.1 24.4 14.9 17.2 2.1 9.3 123.7 21.3 2.3 9.0 9.9 9.7 5.8 4.4 5.5 16.5 16.6 25.7 12.1 15.9 16.4 18.5 14.5 25.8 2.9 14.7 11.9 21.7 19.9 6.2 12.3 15.3 8.4 8.5 6.0 5.1 24.5 22.1 6.5 9.8 15.1 20.3 19.4 12.9 12.6 29.8 6.4 5.3 9.1 16.4 8.3 8.7 6.5 3.0 13.2 10.5 5.7 7.3 11.2 19.3 23.9 5.8 4.3 7.3 18.1 17.5 5.0 4.9 8.8 19.7 8.3 4.7 12.4 2.6 18.4 10.8 0.1 2.7 9.1 6.1 5.8 13.0 14.8 8.2 20.4 7.4 2.1 7.3 8.1 4.8 1.5 5.1 5.3 123.7 2.3 21.3 9.3 9.0 9.9 7.9 10.9 7.9 10.8 9.5 9.4 13.7 6.2 11.2 9.7 44.7 56.9 34.7 63.4 68.3 20.3 10.6 48.4 24.1 23.9 52.4 53.0 48.5 1.7 48.9 61.2 33.8 33.9 0.0 36.5 60.6 44.7 62.7 37.1 38.9 76.7 7.9 8.2 28.8 255.2 27.7 28.4 171.2 38.8 16.2 35.9 11.9 49.2 36.6 18.4 25.1 19.7 58.2 44.3 31.2 36.2 80.0 107.1 69.8 31.9 137.0 RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808063-61894247 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 53.7" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 71.0;Proximal tubular cells: 104.4;Sertoli cells: 64.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 16.3;HBEC3-KT: 8.7;SH-SY5Y: 10.1;TIME: 10.1;U-138 MG: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favorable (1.13e-8)" "prognostic unfavorable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" 8.3 3.9 2.4 2.3 6.8 1.5 8.8 19.1 3.8 8.5 7.4 4.0 6.2 2.2 8.6 10.4 4.5 3.9 8.0 6.5 2.5 3.1 53.7 28.3 7.8 1.2 4.1 1.4 3.8 3.1 4.7 2.6 6.6 7.7 4.7 6.7 3.4 11.8 6.8 4.6 9.6 9.8 4.6 4.2 1.3 5.7 3.9 4.5 0.0 5.1 4.9 2.0 5.0 11.6 0.5 0.4 1.7 0.4 0.6 0.4 0.2 0.0 0.0 3.5 0.8 3.4 0.5 0.0 2.3 7.1 0.5 0.4 0.0 0.1 0.1 0.7 3.6 0.1 16.3 4.4 8.7 1.0 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 0.5 6.0 2.8 1.7 1.6 6.5 0.0 0.0 0.0 1.0 0.7 0.6 0.0 0.2 0.5 0.0 0.2 2.3 0.0 0.3 2.6 3.0 10.1 0.0 6.4 1.1 3.2 3.9 0.0 10.1 16.5 1.7 0.0 0.3 0.0 0.0 0.0 0.5 0.0 5.5 1.7 0.3 0.4 0.2 0.3 0.3 0.3 0.3 0.3 0.2 0.5 0.4 0.4 1.5 0.6 0.4 0.4 0.3 0.2 2.4 6.8 19.1 3.8 2.5 3.1 4.1 1.4 7.7 4.5 0.0 0.0 0.0 21.4 37.5 13.4 2.5 12.7 0.0 2.3 19.2 0.0 0.4 39.7 2.0 0.2 16.3 37.1 0.0 2.4 0.1 8.3 7.3 0.0 71.0 0.1 20.6 15.5 5.5 2.2 0.0 8.1 2.2 27.0 0.0 4.9 3.7 1.1 31.6 17.3 104.4 3.6 64.7 48.4 0.1 0.1 28.4 0.2 0.0 11.8 18.8 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" NA NA "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 30.5 45.9 45.8 32.1 47.0 40.7 38.3 37.9 67.9 44.3 43.5 54.6 49.2 42.7 43.1 55.8 51.6 44.0 47.4 40.1 43.1 39.9 44.1 84.1 35.6 38.7 43.7 43.6 42.6 52.4 52.8 40.7 49.0 41.2 43.6 46.7 38.5 49.1 51.7 56.5 51.6 51.1 42.4 46.4 47.1 42.7 42.0 33.1 53.9 55.1 47.3 47.6 48.1 40.7 25.6 18.2 54.4 26.7 27.6 53.0 37.9 24.2 35.2 15.3 18.8 37.8 18.9 22.9 15.0 21.0 31.7 25.1 24.5 11.2 17.9 29.2 24.8 15.8 37.3 26.6 29.2 23.7 17.3 42.8 30.6 44.4 24.1 28.6 14.4 64.6 22.1 46.1 33.0 31.4 19.9 20.4 26.7 11.9 61.3 25.3 17.3 22.7 17.9 18.3 25.7 22.6 15.7 15.3 22.3 36.5 20.4 12.1 15.0 13.8 23.7 20.0 22.4 22.6 14.7 12.5 19.0 12.6 17.0 28.5 20.4 20.6 5.9 26.1 20.8 19.8 22.4 21.4 54.4 53.0 22.6 41.1 25.6 40.6 52.7 18.2 24.0 28.5 42.3 52.1 27.6 26.7 18.0 37.7 37.9 45.8 47.0 37.9 67.9 43.1 39.9 43.7 43.6 41.2 33.1 0.0 3.8 37.8 33.1 60.9 40.7 13.4 66.2 2.7 2.3 47.1 19.6 101.9 48.0 68.5 41.4 35.8 73.2 46.7 58.4 102.1 39.8 31.4 13.9 83.9 52.2 17.5 30.5 38.1 36.1 68.6 45.1 42.0 37.1 57.7 40.4 45.0 52.7 40.3 50.5 53.1 25.5 38.8 27.8 111.1 83.5 72.8 104.7 90.0 54.4 39.3 RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165844-64372869 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 54.0" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 31.9;Muller glia cells: 32.9;Sertoli cells: 38.8" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "RPMI-8226: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol NA NA Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favorable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" 8.1 8.1 9.9 3.1 12.8 1.6 6.3 6.0 13.0 10.1 7.1 5.5 20.1 3.4 12.7 11.8 6.9 8.1 7.3 10.4 7.4 10.6 12.4 7.2 6.1 3.4 9.4 9.3 12.0 6.6 54.0 16.1 2.0 10.7 11.5 3.0 11.3 7.3 16.4 4.4 6.6 3.2 15.0 11.0 5.1 5.0 8.1 7.1 0.0 20.6 2.5 2.4 10.9 7.9 2.4 1.0 4.2 1.8 2.0 4.2 0.3 0.0 0.1 1.3 0.0 0.0 0.0 0.3 1.1 0.5 1.1 0.6 0.0 0.1 0.0 0.1 0.8 0.6 0.2 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.2 0.1 2.7 0.0 0.1 5.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.5 0.0 1.3 0.1 3.3 25.4 1.9 0.3 0.3 0.1 0.0 0.3 0.0 1.7 1.3 0.1 0.1 0.0 3.2 0.1 2.9 0.0 0.0 0.0 0.5 0.0 3.6 3.0 1.8 4.2 1.9 0.6 2.5 1.4 3.0 3.2 0.6 2.4 4.2 3.9 2.6 2.0 0.8 1.0 1.8 0.3 9.9 12.8 6.0 11.7 7.4 10.6 9.4 9.3 10.7 7.1 14.9 10.5 0.0 6.5 4.0 16.5 9.6 12.7 2.7 7.9 15.7 13.7 0.0 6.6 4.5 3.7 5.6 0.0 0.0 2.3 0.1 2.5 5.0 0.0 5.4 0.1 11.1 1.2 12.3 1.2 5.5 31.9 0.2 5.0 0.0 1.6 32.9 2.8 0.6 23.7 14.3 17.3 38.8 17.9 15.4 9.7 6.5 0.0 0.0 0.1 3.8 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980302 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.9;brain: 17.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 16.5;Horizontal cells: 14.3;Muller glia cells: 15.3;Sertoli cells: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 37.0;RPTEC TERT1: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.2 0.7 7.6 0.6 6.2 12.9 1.2 16.6 17.6 1.2 0.7 7.5 2.0 0.8 1.6 2.5 1.0 2.7 0.9 1.0 11.0 7.3 2.6 0.5 5.7 0.8 6.8 8.5 1.1 3.6 0.5 2.0 2.9 14.3 0.9 0.6 2.2 1.9 4.7 0.9 0.8 1.1 1.0 5.1 0.5 0.6 7.0 2.9 0.0 3.0 0.0 0.4 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.8 5.3 0.0 1.8 2.3 0.3 2.7 3.7 7.5 7.3 0.1 0.0 0.0 0.0 2.9 8.2 0.0 6.2 0.0 13.8 0.0 2.0 0.1 37.0 0.0 0.0 0.0 0.0 1.2 0.0 11.6 0.1 8.7 0.1 1.5 0.2 0.0 5.2 0.0 0.0 0.9 3.0 0.0 10.3 1.5 1.3 0.4 29.7 0.0 6.4 6.1 0.2 0.0 10.4 2.0 0.0 1.0 2.8 9.2 2.0 0.1 6.1 0.0 0.0 0.0 6.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 6.2 16.6 12.1 11.0 7.3 6.8 8.5 14.3 2.9 0.0 0.0 0.0 0.0 0.2 16.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 14.3 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 15.3 0.1 0.0 0.0 0.5 1.2 6.5 0.8 3.0 1.9 0.0 0.2 0.0 0.0 0.0 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160183-31207019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 18.3 16.1 15.2 11.6 20.3 6.8 18.4 16.7 23.4 19.4 17.0 24.3 14.4 15.6 21.8 20.2 20.5 18.3 13.6 15.6 14.7 15.6 27.6 39.7 14.4 11.1 15.9 14.6 21.2 23.5 32.5 24.3 19.8 20.9 30.5 17.3 24.1 27.0 23.5 18.0 22.9 24.4 22.8 16.4 14.4 18.0 11.8 15.1 12.6 39.9 14.4 18.0 19.4 18.5 10.3 12.6 21.5 15.1 15.4 14.0 13.0 9.6 5.7 11.1 12.5 22.5 15.1 10.6 11.5 22.3 15.8 21.5 6.3 4.6 9.2 6.5 20.3 14.0 6.1 10.5 11.9 16.4 9.1 11.4 4.0 5.5 7.7 31.6 9.6 6.2 16.1 42.9 11.1 25.8 14.5 13.2 9.8 4.6 11.0 18.9 6.8 8.3 5.5 4.9 20.0 6.3 8.6 11.0 10.7 11.4 8.4 4.9 9.9 8.4 11.2 16.8 11.9 7.7 6.4 9.2 11.3 8.1 13.0 5.6 15.4 12.5 11.7 14.8 6.2 9.0 15.0 14.6 8.0 12.4 15.1 14.0 10.3 12.7 13.8 12.6 9.0 12.9 11.8 21.5 15.4 12.2 4.7 13.6 13.0 15.2 20.3 16.7 23.4 14.7 15.6 15.9 14.6 20.9 15.1 20.8 9.3 8.3 9.7 8.0 10.1 5.1 12.7 12.0 10.3 17.4 7.9 10.4 18.3 13.4 16.1 8.7 13.4 0.0 12.9 17.5 8.9 12.2 5.7 24.3 12.1 7.9 16.1 27.0 8.1 14.3 6.9 8.8 8.5 11.8 12.0 10.9 13.9 12.7 14.9 18.7 6.7 6.5 8.2 7.0 9.1 9.4 31.1 6.9 7.7 7.4 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487061-228495766 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 42.3;U-266/70: 76.8" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 15.7 30.3 25.6 12.5 28.1 12.3 10.3 33.2 54.7 11.4 10.7 15.5 12.5 14.7 12.9 12.2 18.0 14.2 14.5 17.7 25.2 24.9 16.2 20.4 11.5 9.8 20.2 29.3 20.2 19.4 22.3 16.4 8.8 22.7 15.0 6.6 12.3 30.3 12.6 55.5 15.5 13.2 8.6 16.3 19.0 14.2 9.5 11.4 11.1 27.9 19.4 11.2 10.0 13.1 2.0 1.7 8.7 2.1 1.0 2.3 0.6 9.4 7.1 5.0 10.5 5.5 3.6 9.7 7.9 4.9 5.0 3.8 3.6 6.6 21.6 16.6 9.0 4.1 7.6 6.3 6.7 1.9 9.8 8.1 6.5 5.3 4.7 15.0 7.4 12.8 6.3 12.1 3.8 5.2 6.1 4.4 16.5 10.4 42.3 3.6 5.3 11.8 6.6 11.2 6.7 7.3 10.1 4.6 20.3 3.6 6.0 11.1 11.2 8.1 16.8 21.4 1.7 11.8 17.8 10.1 6.2 6.4 6.7 7.5 76.8 23.0 11.8 16.7 7.8 10.4 0.0 1.1 8.7 1.3 2.1 1.5 1.2 1.5 2.3 1.4 2.0 1.4 1.2 0.3 1.0 1.4 1.7 1.3 0.6 25.6 28.1 33.2 47.3 25.2 24.9 20.2 29.3 22.7 11.4 23.8 13.3 36.1 41.5 32.2 84.0 56.1 38.2 8.1 18.2 38.4 17.7 14.3 96.2 13.8 0.5 22.6 33.3 0.0 20.8 20.1 31.6 30.3 44.9 56.2 24.8 52.4 38.4 29.4 29.7 2.5 22.7 23.8 37.1 6.4 26.7 103.2 20.8 20.4 24.4 99.3 37.8 19.4 38.1 4.4 22.0 48.3 14.8 41.5 27.6 24.7 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Late spermatids: 203.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 60.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved NA NA "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favorable (3.28e-5)" 28.2 13.8 30.2 21.8 20.8 34.9 26.7 16.3 29.5 40.6 22.8 26.4 11.4 17.0 29.4 19.0 17.6 24.7 30.8 20.1 28.7 16.1 23.0 33.9 28.4 35.2 19.7 25.2 24.8 20.3 14.5 15.7 18.6 23.6 20.7 19.2 11.5 19.8 14.2 23.0 26.6 38.5 32.7 30.1 22.7 21.5 35.4 27.7 25.1 17.0 14.7 29.5 33.9 23.7 13.5 11.4 17.6 10.5 4.8 14.4 4.5 8.6 5.6 4.9 5.6 9.3 8.1 6.4 7.8 7.4 7.4 6.8 3.0 5.8 5.1 14.3 7.9 3.4 6.1 3.8 5.7 10.1 21.5 3.1 8.6 25.8 4.3 7.8 1.7 5.5 8.0 8.8 5.9 11.2 9.0 11.3 5.7 4.7 60.1 7.2 4.3 7.8 2.8 1.7 5.8 5.2 3.2 3.4 10.0 20.2 13.6 3.9 8.4 8.1 4.9 7.5 10.7 4.3 6.7 11.2 8.6 6.8 6.3 4.7 29.2 18.7 3.5 5.6 5.7 5.1 17.6 7.5 6.5 14.4 5.6 9.0 13.5 11.8 10.8 4.6 12.7 6.1 8.8 16.6 4.8 10.5 11.4 12.0 4.5 30.2 20.8 16.3 29.5 28.7 16.1 19.7 25.2 23.6 27.7 47.6 39.3 23.5 84.9 35.6 27.9 35.0 84.1 108.4 101.2 41.8 56.9 8.1 6.6 52.3 151.8 52.5 38.7 46.7 35.2 12.6 44.8 62.3 40.6 34.1 19.7 55.6 20.0 30.7 27.9 203.2 54.1 30.2 20.3 9.0 22.2 41.1 43.0 24.6 64.7 42.5 45.0 19.4 28.3 63.0 44.7 52.8 6.9 48.4 18.2 101.9 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964685 "Enzymes, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 16.1" "Cell line enhanced" "Detected in all" "Daudi: 39.3;Karpas-707: 47.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA Cytosol "HPA049587: AB_2680826, HPA063640: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favorable (3.39e-4)" "prognostic unfavorable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 8.6 11.3 8.0 13.1 10.5 36.4 12.0 14.1 14.1 9.9 13.2 10.1 4.8 14.1 10.8 6.9 23.3 7.9 10.1 8.5 6.0 7.2 12.0 6.5 13.8 12.9 9.6 9.3 7.1 7.0 6.4 5.7 9.4 10.2 7.4 15.3 9.0 10.8 5.7 10.2 13.6 15.5 10.6 8.0 9.0 7.4 54.7 8.3 6.8 8.2 11.1 16.7 11.3 12.8 1.3 1.3 16.1 2.0 0.8 1.6 0.7 6.7 5.2 4.5 4.1 2.7 3.9 30.0 3.1 3.8 5.7 6.1 6.1 20.3 39.3 5.5 4.1 7.0 9.7 5.5 7.5 5.2 14.4 3.6 3.4 4.1 6.1 8.8 5.2 7.2 3.1 14.0 12.5 15.4 6.6 11.9 3.9 4.2 47.3 5.5 2.2 3.4 6.4 7.2 7.7 5.9 4.6 6.4 4.0 4.4 9.8 7.1 3.6 10.0 3.4 22.4 11.5 2.9 7.6 13.0 3.1 4.3 7.8 5.4 11.3 5.7 13.9 4.5 5.3 4.6 5.3 2.0 3.5 1.6 1.8 1.2 1.2 1.4 0.8 1.3 1.3 0.4 0.6 16.1 0.8 1.5 0.6 1.5 0.7 8.0 10.5 14.1 14.1 6.0 7.2 9.6 9.3 10.2 8.3 11.9 4.1 1.9 20.3 41.0 4.4 12.0 15.3 6.7 2.3 7.0 2.0 11.0 1.7 9.3 30.1 8.7 34.3 0.0 9.9 5.4 7.1 22.8 4.6 3.4 12.6 3.2 10.9 3.7 20.2 18.4 2.0 28.7 5.0 43.3 16.5 2.0 19.2 17.5 3.5 7.1 7.4 0.0 5.4 29.3 12.6 28.4 6.2 3.2 10.5 35.3 RNF2 "BAP-1, BAP1, DING, HIPI3, RING1B, RING2" ENSG00000121481 "Ring finger protein 2" Q99496 1 185045364-185102608 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatogonia: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026803 Uncertain Enhanced "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA026803: AB_10602086" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-1)" "unprognostic (1.35e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (5.85e-2)" "unprognostic (3.56e-3)" "unprognostic (1.62e-2)" "unprognostic (2.01e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (1.94e-7)" "unprognostic (2.08e-1)" "unprognostic (5.51e-2)" "unprognostic (9.89e-3)" "unprognostic (2.52e-1)" 17.8 15.0 14.3 13.9 12.4 15.3 29.7 15.6 23.6 16.6 12.0 7.8 20.7 10.4 16.2 12.6 15.2 11.5 13.1 12.0 16.0 13.1 13.7 11.1 16.7 20.7 9.4 10.4 19.9 15.0 12.3 26.5 28.4 11.4 13.2 13.5 10.1 17.3 20.6 13.1 12.5 9.8 14.8 11.2 16.2 12.2 27.8 9.4 17.2 15.1 11.5 16.1 17.6 16.9 14.7 19.9 20.6 22.1 17.4 19.4 12.0 13.8 7.6 28.2 11.2 8.0 13.7 26.8 9.8 12.4 15.5 12.5 12.1 23.1 4.1 12.3 12.0 10.5 4.9 19.3 14.2 18.9 12.1 10.1 22.3 4.7 10.6 11.8 22.8 12.6 12.9 8.7 12.7 16.3 12.6 15.6 14.4 17.6 9.9 11.2 8.6 19.7 6.7 37.8 11.7 4.2 22.6 17.5 3.9 11.7 9.8 8.3 14.3 6.8 4.1 19.9 32.0 8.7 12.2 11.0 11.2 14.5 10.6 12.4 16.4 10.6 15.4 7.0 10.8 12.5 19.3 17.0 20.6 13.5 21.1 19.4 14.6 12.5 12.6 19.9 14.7 12.8 12.6 7.9 17.4 22.1 10.0 13.2 12.0 14.3 12.4 15.6 23.6 16.0 13.1 9.4 10.4 11.4 9.4 3.0 5.4 10.8 18.7 20.6 9.2 5.9 7.6 5.3 3.4 8.7 3.9 22.5 19.9 10.5 4.8 17.9 4.0 0.0 11.1 42.7 21.1 12.7 12.7 7.3 17.9 6.4 28.4 21.5 20.3 5.2 8.9 21.4 20.3 28.9 10.4 8.5 10.4 11.5 11.0 10.6 5.9 0.0 12.1 29.9 78.0 17.8 23.8 15.0 11.5 33.6 RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533851-101563344 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA051773" Supported Enhanced Nucleoplasm NA NA Nucleoplasm "CAB012478: , HPA051773: AB_2681604" "unprognostic (7.02e-2)" "unprognostic (2.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.01e-1)" "unprognostic (5.47e-2)" "unprognostic (7.27e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.64e-6)" "unprognostic (2.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-1)" "unprognostic (9.54e-3)" 16.4 17.1 24.6 17.0 24.9 12.1 17.7 24.4 26.3 18.6 16.4 27.7 15.9 10.1 18.3 18.7 20.4 19.1 13.2 24.1 22.3 22.1 20.5 14.4 14.9 15.5 25.2 20.7 21.1 19.5 31.5 23.1 15.1 30.0 21.6 16.1 16.8 16.2 17.7 32.0 16.3 12.5 23.6 28.8 17.0 13.9 28.2 25.8 21.2 22.0 15.3 18.6 21.1 19.0 13.0 12.5 21.0 23.5 13.8 18.6 10.4 9.7 24.8 14.3 15.7 17.7 14.0 12.2 17.0 13.7 17.1 15.0 15.0 10.4 21.6 9.2 13.1 14.3 24.8 16.6 14.5 17.6 22.5 7.7 11.5 22.7 15.0 13.0 19.8 13.9 13.7 15.6 15.1 19.6 12.9 10.0 8.0 10.9 12.8 18.5 12.7 15.4 5.3 31.6 22.0 12.6 14.9 49.6 10.7 7.0 9.4 15.3 19.3 24.1 12.9 14.0 15.0 11.6 9.4 14.1 15.9 16.0 11.3 14.3 13.9 42.7 11.8 14.0 7.5 19.2 21.0 12.7 19.1 18.6 17.5 14.0 13.0 15.4 13.9 12.5 11.2 16.2 14.9 13.9 13.8 23.5 7.9 11.9 10.4 24.6 24.9 24.4 26.3 22.3 22.1 25.2 20.7 30.0 25.8 23.8 24.5 7.5 8.1 5.7 29.1 42.4 10.2 33.5 26.1 21.0 5.9 13.6 5.0 14.3 26.2 11.3 12.2 0.0 12.1 9.6 11.5 7.2 20.9 16.8 14.4 41.3 23.6 7.4 23.8 15.2 16.7 20.0 10.1 27.9 10.7 27.6 10.2 15.3 22.3 9.1 23.0 32.3 14.4 24.7 15.8 5.1 6.4 16.0 12.0 5.4 RNF216 "TRIAD3, UBCE7IP1, ZIN" ENSG00000011275 "Ring finger protein 216" Q9NWF9 7 5620047-5781739 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 118.7;Late spermatids: 171.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018955, HPA021123" Supported Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA018955: AB_1858500, HPA021123: AB_1858501" "unprognostic (3.31e-2)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (1.58e-2)" "unprognostic (1.81e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.40e-2)" "prognostic favorable (6.24e-5)" "unprognostic (2.88e-2)" "unprognostic (9.01e-2)" "unprognostic (3.49e-1)" "unprognostic (1.73e-2)" "unprognostic (1.06e-2)" "unprognostic (3.69e-3)" 16.9 14.9 22.0 18.8 24.8 22.2 18.4 33.5 27.8 17.8 26.9 22.0 13.4 11.5 26.9 13.3 18.7 19.6 14.2 29.1 20.5 17.4 12.7 11.8 14.9 23.8 23.8 14.8 25.6 21.3 23.2 24.9 14.6 20.4 17.7 11.8 18.9 16.2 21.5 22.5 15.1 20.1 25.0 18.7 23.3 18.3 34.3 26.3 18.5 19.8 9.6 24.1 17.7 30.7 8.8 6.7 24.5 8.4 10.0 9.7 6.5 14.3 15.4 12.7 21.6 15.2 13.1 8.7 15.3 16.1 15.9 14.8 11.1 8.2 12.5 7.9 17.1 27.6 10.3 13.1 10.8 13.0 7.8 11.4 9.7 9.3 11.2 18.1 15.8 16.6 13.5 13.8 12.2 14.9 13.2 12.6 12.2 19.3 8.8 17.6 22.0 5.9 25.2 17.4 8.1 12.9 15.1 17.9 7.0 9.5 12.1 9.7 15.4 9.7 24.3 8.7 14.9 9.6 16.2 13.6 16.1 29.1 16.4 13.8 7.2 5.3 10.2 12.1 14.7 25.6 1.3 7.7 24.5 9.0 8.4 9.0 7.3 7.9 6.7 6.7 8.8 9.7 9.1 13.1 10.0 7.7 5.4 7.0 6.5 22.0 24.8 33.5 27.8 20.5 17.4 23.8 14.8 20.4 26.3 6.0 19.2 11.0 16.6 14.7 36.2 25.7 5.1 13.4 14.8 12.2 49.1 11.9 21.6 15.1 118.7 24.8 10.2 0.0 12.0 11.1 20.5 16.4 18.5 13.4 19.2 27.0 5.8 23.9 19.0 171.4 34.5 23.8 11.8 33.3 12.5 35.8 13.1 3.5 28.3 10.6 49.0 25.8 22.7 96.9 99.0 14.2 12.7 23.0 10.8 13.1 RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962545-125092633 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 63.3" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 1.9;myeloid DC: 1.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain NA NA "HPA029598: AB_10602297" "unprognostic (2.96e-2)" "unprognostic (2.34e-3)" "unprognostic (8.07e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (4.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.47e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (4.60e-5)" "unprognostic (8.29e-4)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" "prognostic unfavorable (1.92e-4)" 9.6 3.5 3.3 4.2 4.7 10.5 14.6 3.8 3.5 8.0 7.7 5.7 6.4 2.3 5.9 5.6 6.2 7.5 12.1 6.5 3.8 1.7 2.5 6.3 7.3 3.7 4.3 2.9 11.5 3.8 63.3 4.0 12.0 3.4 6.4 2.3 6.0 6.0 6.9 10.1 10.9 3.1 13.0 2.3 2.6 4.5 7.4 5.7 0.1 7.4 3.6 1.6 8.7 13.6 0.0 1.2 0.6 1.9 0.3 0.2 0.3 4.1 4.3 1.5 0.5 5.4 2.1 8.6 5.7 7.7 3.9 5.1 0.0 3.9 0.0 8.0 5.4 8.9 6.0 0.9 5.1 5.5 0.0 4.8 2.3 6.4 1.3 5.2 0.0 0.2 5.9 4.8 2.9 8.6 4.6 4.4 0.0 11.6 0.0 6.8 0.0 0.0 0.0 1.3 0.0 1.1 0.1 6.0 0.0 4.0 1.9 0.7 0.0 2.5 0.6 2.2 4.4 4.2 0.7 6.9 3.2 10.4 0.0 12.2 0.0 0.0 0.0 2.4 0.0 3.8 0.6 1.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.3 3.3 4.7 3.8 3.5 3.8 1.7 4.3 2.9 3.4 5.7 20.8 16.0 0.0 12.7 42.7 6.2 12.5 2.5 5.3 10.3 5.2 15.7 15.2 0.0 6.8 92.0 15.0 1.7 0.0 8.3 23.6 21.6 10.4 1.1 24.6 8.5 20.6 2.9 14.1 12.9 49.9 23.9 13.3 18.6 2.8 3.0 4.0 10.7 0.0 19.8 1.9 5.0 6.5 12.3 1.4 2.6 41.0 15.0 0.5 2.7 9.7 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663864-218672411 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA Cytosol "Nucleoplasm, Actin filaments" "HPA036420: AB_2675114, HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 13.4 12.7 13.9 11.1 16.1 6.2 13.7 13.4 27.6 17.3 13.3 17.1 9.8 4.3 16.6 16.2 12.2 16.8 11.8 17.2 13.1 16.5 13.7 15.6 11.9 12.1 12.1 11.6 17.8 13.0 19.3 14.8 17.7 15.4 14.7 9.0 15.3 13.6 17.9 16.9 15.7 10.3 16.0 10.0 12.9 11.8 18.4 9.1 15.3 16.8 12.7 16.8 14.0 11.8 13.3 8.2 23.3 11.2 14.8 15.0 13.9 5.9 7.6 6.9 8.0 10.6 6.5 7.5 6.8 17.1 23.4 21.8 12.7 4.0 4.0 5.4 14.3 12.9 5.4 8.0 13.3 10.2 4.3 10.9 5.4 5.6 12.0 13.0 4.8 5.9 14.3 12.4 21.2 14.3 6.5 12.7 15.4 9.1 6.2 15.0 17.0 5.4 5.9 11.0 4.9 8.7 7.6 4.4 5.8 14.3 6.4 7.0 7.9 5.2 5.9 10.1 5.0 7.0 8.8 7.3 13.3 6.3 5.2 9.6 5.4 4.2 6.7 11.2 6.0 8.0 23.3 10.6 14.9 13.9 10.3 12.6 11.9 13.7 13.6 8.2 13.3 15.0 11.7 8.9 14.8 11.2 7.4 11.5 13.9 13.9 16.1 13.4 27.6 13.1 16.5 12.1 11.6 15.4 9.1 0.0 0.3 4.7 4.6 5.6 7.4 3.1 5.1 5.3 2.3 1.8 7.9 11.1 13.3 10.5 10.3 5.9 6.4 0.0 11.4 8.1 7.2 3.0 6.9 6.4 11.3 4.8 1.2 9.2 5.9 3.4 6.6 4.6 8.5 10.0 4.9 7.0 10.2 8.6 12.0 11.5 4.5 25.8 6.1 14.4 11.9 5.9 8.4 10.1 4.8 3.9 RNF31 "FLJ10111, FLJ23501, HOIP, Paul, ZIBRA" ENSG00000092098 "Ring finger protein 31" Q96EP0 14 24146683-24160661 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 5.8;Club cells: 5.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009063, HPA048745" Approved Approved Cytosol NA NA Cytosol "CAB009063: AB_2127706, HPA048745: AB_2680509" "unprognostic (3.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (9.05e-2)" "unprognostic (2.52e-1)" "unprognostic (6.24e-2)" "unprognostic (9.09e-3)" "unprognostic (1.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (6.21e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-1)" 14.4 18.5 11.7 21.5 17.4 20.0 15.1 20.0 26.4 17.7 17.3 18.4 19.9 13.4 22.4 22.3 15.4 17.4 17.2 14.5 10.7 9.8 17.2 14.8 15.3 19.3 11.0 18.0 20.6 23.6 20.0 19.2 18.7 13.4 16.4 14.1 16.9 19.6 23.1 39.5 29.1 16.1 19.7 9.1 27.3 16.5 21.8 11.0 33.6 17.4 13.1 24.9 16.3 13.5 2.4 4.6 3.8 3.7 2.5 4.8 1.3 4.5 10.6 9.9 12.2 6.7 7.0 20.1 7.9 11.7 15.6 12.5 9.6 11.5 9.0 5.0 11.3 9.2 7.8 5.6 11.3 9.3 9.4 4.2 8.4 10.8 21.0 11.1 14.1 15.0 12.8 9.7 7.1 11.1 9.7 9.9 7.5 4.9 11.9 6.9 14.1 13.3 8.3 5.3 7.9 11.6 8.9 7.3 5.7 7.9 18.8 8.8 11.0 7.3 19.3 9.6 9.0 6.8 10.4 9.7 11.0 8.4 8.0 7.4 16.0 14.1 8.8 4.1 5.6 10.2 0.0 2.1 1.5 1.9 3.7 4.8 2.4 1.9 2.1 1.8 1.1 2.3 1.3 3.8 2.5 2.1 4.6 3.0 1.3 11.7 17.4 20.0 26.4 10.7 9.8 11.0 18.0 13.4 11.0 0.0 5.8 0.5 0.2 0.6 0.7 0.2 0.0 1.4 5.7 0.0 0.0 0.4 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.3 0.4 0.2 0.0 0.6 0.3 0.0 0.0 0.6 0.8 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.7 0.0 0.1 0.7 0.4 0.6 0.5 0.8 0.0 0.3 RNF40 "BRE1B, KIAA0661, RBP95, STARING" ENSG00000103549 "Ring finger protein 40" O75150 16 30761745-30776307 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Distal tubular cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041330, HPA054227" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA041330: AB_10793872, HPA054227: AB_2682422" "unprognostic (1.61e-1)" "unprognostic (1.74e-2)" "unprognostic (3.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.21e-1)" "unprognostic (4.01e-1)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-2)" "unprognostic (1.91e-2)" "prognostic favorable (8.11e-8)" "unprognostic (9.96e-2)" "unprognostic (1.36e-1)" "unprognostic (6.55e-3)" "unprognostic (6.60e-3)" 21.0 25.2 26.4 21.3 26.5 40.8 20.9 36.8 28.2 25.8 21.0 22.0 18.0 20.1 28.4 17.0 25.6 24.4 21.3 22.8 22.2 17.1 20.0 21.2 20.2 21.9 20.9 18.9 30.5 24.4 44.0 21.6 25.3 19.6 21.4 15.1 20.0 27.3 21.1 20.0 25.5 20.3 18.3 18.6 20.0 19.6 43.1 22.8 23.5 26.8 15.4 20.6 22.5 21.4 7.6 12.0 15.0 14.9 9.9 13.3 12.9 20.3 31.9 19.4 18.4 14.8 15.5 21.2 20.8 16.1 24.1 18.8 25.8 19.0 16.2 30.6 17.8 16.5 22.1 35.3 18.5 18.9 23.2 41.4 15.9 35.0 26.7 19.8 27.4 18.6 14.4 15.5 30.2 17.1 16.1 20.2 14.4 34.8 15.5 14.6 34.0 26.1 25.8 20.2 16.3 19.3 51.9 21.4 31.2 10.6 18.1 32.4 23.8 16.3 20.9 15.1 10.7 32.0 31.2 21.8 27.1 13.8 19.1 23.7 23.2 28.5 32.2 22.5 24.4 27.6 6.2 11.5 14.7 12.9 13.4 13.3 7.6 7.2 9.9 12.0 6.5 5.4 8.3 15.0 9.9 14.9 6.2 6.2 12.9 26.4 26.5 36.8 28.2 22.2 17.1 20.9 18.9 19.6 22.8 11.9 26.4 10.4 10.9 12.4 14.5 2.0 30.6 9.4 11.4 21.0 3.9 13.3 74.6 12.9 18.8 10.9 22.6 0.0 11.6 13.8 11.8 14.0 4.6 18.7 18.7 4.8 13.4 9.8 24.6 16.8 16.7 13.0 16.9 9.0 20.9 16.6 13.6 14.0 16.6 19.9 13.3 12.9 11.2 19.7 9.4 17.2 19.0 13.6 23.6 10.0 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202175-56221933 "Enzymes, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" NA NA "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 22.2 17.6 18.6 11.8 30.2 12.0 14.3 30.9 47.1 16.2 15.0 16.9 12.3 8.5 16.4 9.7 16.5 17.7 18.0 22.6 17.3 22.4 14.1 10.5 16.5 14.8 15.3 18.2 17.0 16.0 17.9 16.7 14.6 25.3 25.2 13.6 14.6 10.5 15.6 21.2 10.1 10.8 20.3 11.8 13.5 12.2 10.1 12.1 11.3 20.5 10.1 17.0 16.2 11.5 24.6 13.1 41.1 11.5 13.4 12.5 12.3 7.5 11.6 12.6 20.0 26.5 19.3 9.4 25.3 25.1 22.8 18.6 14.2 9.9 14.6 13.5 21.4 7.6 8.7 17.0 12.2 16.6 15.3 9.3 19.6 8.3 8.1 55.6 21.4 21.4 24.6 28.7 19.0 33.6 30.1 22.1 12.4 13.9 15.0 12.6 12.2 12.2 9.6 15.2 7.6 13.6 13.3 9.1 8.8 12.1 11.1 23.1 14.0 22.1 12.7 20.0 13.2 17.8 25.2 13.3 11.5 12.3 14.8 9.8 10.8 12.4 13.3 13.7 12.9 13.7 21.0 11.5 41.1 12.5 11.4 11.2 22.7 10.6 10.9 13.1 24.6 11.0 11.2 15.8 13.4 11.2 10.2 12.1 12.3 18.6 30.2 30.9 47.1 17.3 22.4 15.3 18.2 25.3 12.1 41.7 26.4 27.0 18.8 10.6 26.2 20.1 25.5 24.1 25.0 15.7 21.6 13.2 14.9 14.3 78.7 16.4 9.3 23.3 18.6 14.4 14.9 30.9 24.4 14.9 17.6 27.0 19.5 22.1 29.2 38.0 21.3 21.9 6.8 21.6 13.2 23.9 17.8 16.1 24.4 15.8 16.9 25.8 21.4 9.9 12.2 14.4 14.1 15.0 13.6 16.9 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178354-32180793 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Proximal tubular cells: 293.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 9.8 20.6 19.3 9.0 20.6 10.3 14.0 13.6 16.8 11.3 25.7 17.4 14.7 18.1 12.3 14.6 15.9 16.9 13.9 19.2 16.9 12.0 32.7 38.1 14.7 11.6 16.3 14.2 19.0 19.3 7.2 5.8 23.4 12.3 13.1 19.1 12.2 25.3 15.3 24.5 13.4 36.7 13.7 19.7 10.2 14.2 9.6 9.6 10.8 18.0 14.2 12.5 13.2 9.9 6.7 26.9 7.2 6.4 7.5 7.0 6.5 5.3 6.9 4.7 18.1 5.2 3.6 3.7 2.1 2.7 4.7 5.4 9.2 4.5 6.9 7.8 5.2 6.7 4.4 8.8 4.9 5.0 4.3 11.9 5.5 7.8 19.0 6.1 0.0 11.3 3.5 6.6 7.9 6.0 8.6 9.5 12.4 14.1 7.5 6.8 7.5 6.7 15.9 0.0 7.5 2.9 4.6 5.3 9.7 13.3 3.4 4.9 10.2 4.2 4.5 4.7 4.4 9.4 19.4 4.2 5.2 5.1 0.0 8.2 4.1 6.2 8.2 3.6 12.3 3.0 5.1 4.6 7.2 7.0 6.4 6.1 6.7 5.7 6.2 6.6 6.0 6.4 6.3 2.4 7.5 4.5 26.9 5.7 6.5 19.3 20.6 13.6 16.8 16.9 12.0 16.3 14.2 12.3 9.6 17.9 31.3 63.3 54.1 85.1 21.8 54.9 81.5 48.2 43.3 87.2 0.0 66.6 240.4 91.9 15.7 46.6 171.7 70.0 79.3 85.9 60.9 53.6 54.4 112.5 61.3 31.8 70.3 41.7 42.8 15.3 55.0 53.8 81.0 88.4 77.1 59.7 70.4 152.6 68.2 293.3 20.3 64.7 69.2 57.6 36.2 73.8 70.4 52.4 93.3 42.3 RNF8 KIAA0646 ENSG00000112130 "Ring finger protein 8" O76064 6 37353972-37394738 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Host-virus interaction, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 40.7" "Low region specificity" "Detected in all" "HPA050731, HPA064925" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA050731: AB_2681222, HPA064925: AB_2685385" "unprognostic (1.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.39e-2)" "unprognostic (8.20e-2)" "unprognostic (5.17e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (3.33e-5)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (2.26e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (3.41e-2)" "unprognostic (3.66e-3)" "unprognostic (1.09e-1)" 8.0 11.7 13.1 8.2 17.8 8.9 11.5 25.7 18.7 9.2 9.5 10.6 6.8 6.9 13.5 5.7 18.3 12.0 8.8 17.6 13.4 14.8 11.8 7.5 10.8 8.3 12.0 16.0 13.2 6.5 11.9 16.4 10.2 13.7 8.6 8.2 8.0 10.2 11.9 15.2 9.9 8.4 10.7 9.6 7.7 7.6 19.8 13.8 6.6 8.0 9.4 13.3 12.9 15.2 8.8 8.3 2.6 8.1 7.6 10.8 5.5 6.6 4.0 9.7 11.5 7.8 11.3 2.8 6.9 8.6 13.2 14.5 6.0 3.7 8.3 4.2 6.7 11.4 6.3 13.5 8.8 13.8 8.7 13.1 14.2 7.0 8.9 4.5 7.6 10.5 5.6 8.5 7.8 9.1 8.1 12.6 9.8 9.6 2.9 7.5 4.4 9.1 9.4 6.7 3.4 5.3 7.2 8.9 5.7 6.7 4.7 19.1 6.4 5.2 5.9 9.5 6.6 5.3 7.4 5.7 8.7 7.7 8.2 10.2 8.6 11.3 40.7 4.2 10.8 10.0 1.0 4.6 2.6 10.8 6.0 10.0 8.8 8.1 10.2 8.3 6.0 7.1 9.4 0.6 7.6 8.1 3.6 9.3 5.5 13.1 17.8 25.7 18.7 13.4 14.8 12.0 16.0 13.7 13.8 17.9 23.4 13.0 21.7 16.3 26.0 28.3 10.2 28.1 15.9 24.4 37.3 20.9 13.3 20.8 35.2 15.8 8.6 0.0 16.6 21.6 23.9 20.0 27.7 14.7 15.4 47.7 21.4 22.1 14.2 20.2 24.7 13.8 10.1 20.8 16.1 21.5 23.6 15.6 29.0 16.8 29.6 12.9 16.4 43.0 33.1 19.3 4.9 15.8 16.2 17.0 RNGTT "hCAP, HCE, HCE1" ENSG00000111880 "RNA guanylyltransferase and 5'-phosphatase" O60942 6 88610272-88963721 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA capping, mRNA processing" "Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Protein phosphatase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003750 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA003750: AB_1856383" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (2.82e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.48e-3)" "unprognostic (1.28e-1)" "unprognostic (4.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-3)" "unprognostic (9.83e-2)" "unprognostic (6.55e-2)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" 9.1 12.1 10.2 19.6 12.2 14.2 9.9 18.5 13.1 10.0 8.1 8.7 7.0 7.4 11.1 7.2 12.5 8.7 7.2 9.6 10.5 16.0 9.4 11.8 9.4 26.3 9.8 6.4 10.4 6.6 12.1 23.1 11.6 11.1 9.8 9.8 9.4 8.4 11.6 10.5 9.0 10.7 10.7 10.7 14.3 7.5 15.0 10.4 28.0 10.0 7.8 28.2 10.9 13.8 18.6 4.4 5.7 4.6 8.0 8.4 4.3 5.7 8.8 13.7 17.5 8.1 8.5 8.2 13.2 8.6 10.7 13.6 10.0 4.4 14.9 10.8 9.4 14.2 7.2 16.0 10.6 19.7 20.2 12.5 19.3 7.9 8.0 6.6 20.7 11.0 5.4 9.3 11.1 10.8 9.2 9.4 8.2 19.1 12.0 15.8 7.6 9.1 14.8 8.2 9.5 7.7 18.0 21.2 8.4 9.6 8.9 8.1 11.6 10.9 6.6 7.2 13.6 7.1 20.8 7.5 8.7 8.0 9.8 17.7 10.9 19.0 8.4 12.8 15.5 15.8 3.5 3.0 5.7 6.4 4.6 6.4 18.6 7.2 7.9 4.4 16.8 8.2 8.4 2.5 8.0 3.9 3.1 6.7 4.3 10.2 12.2 18.5 13.1 10.5 16.0 9.8 6.4 11.1 10.4 0.0 18.1 34.7 7.8 7.3 19.8 9.2 2.5 13.4 18.2 12.2 37.3 8.7 0.0 5.7 4.9 4.7 5.9 0.0 4.3 8.0 7.1 6.8 8.1 8.6 6.7 14.3 8.7 6.2 7.5 3.6 5.5 9.8 3.3 6.4 5.7 8.7 5.6 3.5 7.4 5.8 43.3 6.5 7.5 19.9 21.7 7.5 9.8 13.8 6.3 5.8 RNMT RG7MT1 ENSG00000101654 "RNA guanine-7 methyltransferase" O43148 18 13726660-13764558 "Enzymes, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039409 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA Nucleoplasm "Nucleoli fibrillar center" "HPA039409: AB_10795289" "unprognostic (3.02e-1)" "unprognostic (1.07e-2)" "unprognostic (3.48e-1)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (3.04e-1)" "unprognostic (6.17e-3)" "unprognostic (1.43e-1)" "unprognostic (3.76e-2)" "unprognostic (1.42e-3)" "unprognostic (9.45e-2)" "unprognostic (9.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.77e-2)" "unprognostic (1.78e-1)" 18.9 10.1 13.3 12.7 20.4 40.1 16.6 19.7 27.3 14.0 11.5 10.3 12.1 9.1 15.4 13.1 12.6 12.2 9.9 21.2 14.9 18.2 12.9 12.0 12.4 14.6 14.5 21.8 19.6 13.3 16.6 21.2 16.1 28.5 14.7 11.6 10.8 12.8 12.2 29.1 14.3 11.3 15.1 16.1 12.3 11.4 17.1 12.6 12.2 19.2 15.8 15.8 26.5 11.4 20.1 20.8 21.6 13.1 9.4 15.7 4.1 11.5 6.8 13.3 10.0 9.9 12.6 9.3 9.5 11.8 9.9 13.5 8.1 5.6 12.9 11.7 9.7 15.4 4.7 15.7 13.6 16.7 7.1 8.4 9.7 7.0 7.6 10.9 25.3 8.3 9.6 14.8 10.4 29.4 13.0 7.6 14.8 14.5 13.0 11.2 7.2 16.1 9.1 10.1 23.4 5.3 10.5 14.1 17.5 9.1 9.1 10.3 15.5 10.7 7.9 18.2 14.2 6.8 10.6 7.8 19.9 28.0 16.1 10.1 26.2 28.5 26.8 14.6 9.7 9.9 21.6 13.1 8.5 12.5 10.3 10.1 16.2 11.9 10.3 8.1 20.1 15.7 12.2 7.1 9.4 11.4 20.8 12.8 4.1 13.3 20.4 19.7 27.3 14.9 18.2 14.5 21.8 28.5 12.6 68.5 25.1 34.8 48.8 62.5 108.1 45.4 17.8 33.5 27.3 43.6 115.8 54.2 58.0 42.6 22.7 38.6 37.3 0.0 41.9 49.2 49.0 53.0 34.6 31.8 35.7 100.1 71.9 33.2 58.5 8.0 67.3 52.8 47.2 39.7 36.5 38.3 46.4 37.6 57.3 53.0 142.0 38.8 52.5 78.5 106.7 59.7 105.7 61.8 39.2 36.6 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111851 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 335.7;Late spermatids: 390.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved NA NA 240000 "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: AB_2679401" "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavorable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 19.3 9.7 9.7 16.3 9.7 40.0 15.1 18.3 11.0 13.9 12.6 7.1 14.4 10.1 16.0 14.9 13.3 14.4 11.7 11.9 10.3 5.6 10.5 9.2 17.0 20.5 10.1 6.0 13.7 9.5 11.2 12.2 11.5 10.3 14.2 9.4 9.5 9.4 9.8 7.9 8.5 11.6 27.7 10.7 17.3 12.0 6.6 12.4 24.8 10.9 9.6 11.2 17.9 21.0 5.4 5.3 17.9 5.0 2.6 5.1 2.0 6.4 4.0 4.0 3.9 7.6 8.2 6.6 9.0 4.4 4.0 4.4 6.7 2.8 8.0 6.5 10.6 2.2 5.3 3.6 5.2 8.2 11.3 4.2 6.4 7.4 2.9 3.9 17.6 10.0 5.9 4.8 6.0 4.9 3.3 6.1 3.2 3.6 8.3 4.7 4.1 8.3 3.8 3.4 4.3 6.8 11.8 4.7 3.1 3.9 6.0 4.7 3.7 7.2 4.9 3.6 3.8 4.8 6.7 10.1 8.2 6.8 7.3 7.3 11.4 5.1 9.2 6.1 7.6 5.0 2.8 5.0 6.3 5.1 3.1 4.1 3.7 3.8 3.9 4.0 5.4 3.7 3.6 17.9 2.6 3.6 5.3 3.2 2.0 9.7 9.7 18.3 11.0 10.3 5.6 10.1 6.0 10.3 12.4 89.3 78.4 61.5 52.6 41.1 96.1 123.9 25.5 57.6 86.4 31.4 123.7 47.6 13.3 52.8 335.7 72.9 30.7 0.0 33.3 52.8 65.1 50.5 69.5 41.2 54.5 57.2 95.0 46.1 128.2 390.9 90.3 132.9 62.4 85.6 37.7 47.5 51.9 60.4 130.4 14.9 135.4 168.1 157.5 68.9 76.9 32.0 35.9 96.4 35.1 57.6 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179761-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 3700000 Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 26.9 7.8 14.6 9.5 21.9 4.4 21.4 26.1 26.4 16.6 16.5 5.6 8.6 12.3 22.4 11.0 12.4 13.2 11.9 12.3 13.4 7.6 11.4 12.3 16.7 6.8 7.2 16.7 15.1 8.6 12.9 14.8 18.4 10.3 14.4 20.3 5.6 10.3 14.4 28.0 8.7 13.8 42.9 7.1 12.6 10.7 5.8 9.6 5.9 10.5 5.1 6.2 22.1 20.8 2.5 3.0 3.6 2.2 3.5 3.3 0.9 6.6 16.2 13.4 13.1 24.3 17.1 8.6 15.8 14.8 10.3 10.9 15.3 14.6 8.4 9.4 24.9 12.5 7.4 9.7 9.1 16.3 11.9 5.8 16.7 27.9 30.5 8.7 9.3 4.8 13.3 5.8 12.7 9.1 8.4 16.4 4.6 14.5 3.4 15.3 5.6 6.8 4.8 7.4 14.1 10.0 8.2 29.5 2.7 5.6 18.9 6.3 6.8 31.0 10.8 10.8 10.6 4.4 5.2 22.3 21.3 15.4 8.4 13.8 2.7 3.3 7.5 9.2 11.0 29.6 3.6 1.8 1.7 2.7 2.2 3.3 1.6 2.2 1.8 1.3 2.5 1.9 2.1 3.0 3.5 1.7 3.0 1.8 0.9 14.6 21.9 26.1 26.4 13.4 7.6 7.2 16.7 10.3 9.6 107.2 64.4 9.3 35.3 35.4 33.2 94.7 35.7 41.5 86.4 21.0 55.0 22.5 1.7 25.4 6.5 88.7 62.6 0.0 34.0 15.9 43.2 45.6 26.7 37.6 16.5 76.3 20.4 58.9 19.8 3.5 40.6 24.0 21.9 8.2 82.3 34.2 30.5 38.6 73.9 13.6 42.5 129.4 101.5 21.4 17.7 24.3 26.3 11.4 40.0 38.2 RORA "NR1F1, ROR1, ROR2, ROR3, RZRA" ENSG00000069667 "RAR related orphan receptor A" P35398 15 60488284-61229319 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 64.8" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 428.0;Suprabasal keratinocytes: 370.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Lineage enriched" "Detected in many" 4 "T-cells: 16.9" "Cell line enhanced" "Detected in many" "Karpas-707: 35.1;U-266/70: 20.1;U-266/84: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009861 Approved NA NA "CAB009861: AB_2180141" "unprognostic (1.57e-1)" "unprognostic (4.76e-2)" "unprognostic (2.22e-1)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (2.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (9.93e-2)" "unprognostic (1.34e-1)" "prognostic favorable (5.42e-6)" "unprognostic (6.94e-2)" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.62e-2)" 8.6 32.4 8.1 6.0 9.8 12.2 12.0 29.8 17.0 7.6 6.1 4.8 11.9 2.7 7.5 6.7 14.8 5.4 8.1 6.7 8.7 4.2 11.2 23.1 10.0 5.9 7.8 7.0 8.9 11.8 11.8 10.3 4.1 10.0 5.4 3.5 9.1 7.8 12.0 34.6 64.8 6.2 7.8 11.0 7.7 5.5 11.2 9.3 1.5 11.1 9.9 8.8 8.9 10.3 0.8 0.4 0.3 0.0 3.7 16.9 2.6 0.0 0.4 1.3 0.0 1.7 0.8 0.4 0.6 0.7 0.5 0.7 0.8 0.2 0.0 0.3 1.6 1.7 0.2 2.9 1.2 1.0 1.3 2.4 0.0 0.1 1.3 0.6 0.0 0.1 3.8 0.3 1.6 0.0 0.5 5.5 5.3 0.1 35.1 2.4 0.1 0.3 0.0 1.0 0.8 0.5 0.0 1.1 0.5 1.1 0.2 0.9 2.1 0.1 0.3 0.0 3.7 0.0 0.0 0.1 4.9 2.2 2.0 0.0 20.1 27.8 0.1 8.3 0.0 0.5 0.1 0.0 0.0 14.7 0.0 16.9 0.8 11.1 9.9 0.0 0.1 3.5 7.4 0.3 3.7 0.0 0.4 9.3 2.6 8.1 9.8 29.8 17.0 8.7 4.2 7.8 7.0 10.0 9.3 38.7 31.4 12.3 26.8 164.5 162.1 20.4 28.1 16.0 22.7 55.8 428.0 0.5 11.6 15.3 133.0 32.2 1.0 23.3 10.8 1.0 44.1 23.1 2.3 75.9 0.7 119.2 17.7 31.9 6.6 58.8 43.1 8.9 57.3 1.0 2.0 48.1 11.9 0.0 82.0 34.9 155.0 38.8 31.6 1.4 2.4 370.0 3.9 142.8 1.5 50.2 RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92298965-92402056 "Enzymes, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Cone photoreceptor cells: 104.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046443 Approved Supported Nucleoli,Cytosol No No "Nucleoli, Cytosol" "HPA046443: AB_2679669" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.71e-2)" "unprognostic (4.12e-2)" "unprognostic (4.96e-3)" "unprognostic (5.73e-2)" "unprognostic (1.23e-3)" "unprognostic (3.29e-2)" "unprognostic (8.01e-3)" "unprognostic (4.09e-2)" "unprognostic (2.59e-1)" "unprognostic (6.09e-2)" "unprognostic (7.02e-4)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.62e-3)" "unprognostic (4.10e-2)" 6.8 7.0 7.8 7.3 10.5 12.0 7.6 27.2 11.6 8.4 6.3 7.1 7.2 6.6 11.1 11.5 5.6 6.3 5.5 5.9 8.1 8.6 8.1 10.6 5.2 8.2 7.7 6.7 8.2 8.6 9.4 16.1 6.7 11.7 7.6 5.8 6.4 7.2 7.1 10.5 10.7 6.3 7.4 9.9 7.6 6.4 6.7 8.7 12.8 9.4 6.5 6.3 6.6 7.6 4.4 3.5 4.9 2.4 4.0 4.8 1.2 6.3 3.9 6.8 6.3 5.6 7.2 5.8 5.0 3.5 3.3 2.7 2.8 2.9 9.5 8.7 3.7 4.5 4.4 5.6 3.2 5.1 6.5 4.0 5.8 7.0 3.7 3.3 10.0 5.8 3.7 4.0 4.2 4.1 4.9 3.5 5.9 5.9 6.4 5.0 3.3 8.4 6.3 5.3 3.6 4.4 6.3 9.0 4.1 4.3 5.7 6.4 4.7 8.1 7.5 4.0 5.3 3.9 7.7 6.1 5.0 6.4 5.7 7.1 6.2 7.1 5.0 3.5 6.3 3.4 4.8 2.4 1.9 4.1 1.7 4.8 3.4 3.2 3.5 1.8 4.4 3.5 3.8 4.9 4.0 1.9 3.5 2.8 1.2 7.8 10.5 27.2 11.6 8.1 8.6 7.7 6.7 11.7 8.7 59.6 66.2 8.2 15.1 8.1 55.5 21.2 5.1 75.0 68.2 7.0 104.1 17.6 10.0 16.4 39.3 17.1 7.7 23.3 11.9 12.3 13.6 12.8 59.1 7.4 8.5 33.4 12.1 8.0 10.8 4.7 17.5 8.8 1.7 15.4 11.9 39.3 12.8 10.7 20.1 13.0 87.8 25.8 12.0 18.9 18.8 8.5 19.8 24.2 11.1 9.8 RPS6KA1 "HU-1, p90Rsk, RSK, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 45.2" "Cell type enhanced" "Detected in many" 6 "Enterocytes: 85.8;monocytes: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.9;U-937: 32.2" "Region enriched" "Detected in all" 5 "cerebellum: 60.4" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favorable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.84e-4)" "prognostic favorable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favorable (8.33e-4)" 11.0 8.2 6.3 24.2 9.7 15.8 5.0 14.4 6.3 4.9 23.2 11.1 4.4 24.5 2.1 3.6 8.9 6.0 8.0 3.4 5.3 5.1 13.6 5.4 26.1 32.7 10.3 3.5 2.1 10.1 10.0 7.4 3.3 8.6 8.6 15.8 3.6 19.0 5.5 1.1 9.0 45.2 2.8 7.9 27.0 9.7 2.7 9.0 15.9 13.9 4.9 17.3 6.2 4.5 5.0 22.0 40.1 18.0 7.9 8.3 17.1 9.9 3.5 2.8 3.7 0.1 0.0 3.8 0.8 1.6 4.2 4.1 4.0 8.2 18.5 4.6 0.5 5.1 11.7 6.4 22.9 3.0 15.3 4.1 20.3 8.6 7.1 1.3 23.9 29.9 0.7 8.4 3.9 7.0 1.9 1.8 7.4 3.4 6.7 0.2 5.5 0.8 23.6 7.3 19.3 11.1 12.8 3.6 8.1 12.1 2.7 4.1 1.6 7.0 6.6 3.2 3.1 4.2 20.6 1.2 0.2 5.4 0.7 3.3 4.2 4.9 10.1 2.5 32.2 4.1 9.6 18.0 40.1 8.3 16.4 6.9 4.9 6.1 7.3 22.0 5.0 3.9 5.5 34.5 7.9 17.3 8.6 6.0 17.1 6.3 9.7 14.4 6.3 5.3 5.1 10.3 3.5 8.6 9.0 14.9 23.5 13.7 7.4 16.6 1.3 1.2 10.2 10.7 5.7 8.7 3.9 1.2 6.6 15.5 1.8 4.2 85.8 0.0 16.3 14.5 1.9 13.9 32.2 3.8 43.9 0.0 15.6 12.3 57.1 0.5 0.0 36.8 1.7 68.5 34.3 0.4 21.8 41.9 0.0 13.6 1.7 6.5 2.1 1.1 2.7 10.2 3.4 41.5 32.9 6.8 RPS6KA2 "HU-2, RSK, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "eosinophil: 17.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.5" "Cell line enhanced" "Detected in many" "ASC diff: 48.4;ASC TERT1: 35.5;HHSteC: 35.9;HSkMC: 31.9;hTERT-HME1: 38.6;hTERT-RPE1: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 15.4 6.5 26.8 5.3 35.5 6.9 12.7 12.1 21.5 13.5 7.1 20.3 11.5 4.3 18.3 5.2 14.0 11.9 12.5 40.9 25.0 18.3 9.9 3.3 24.6 10.6 22.4 18.4 20.9 30.2 32.6 18.0 12.1 22.7 10.6 7.4 11.1 9.0 10.5 14.4 7.5 7.2 15.8 37.2 16.5 10.4 5.1 25.7 0.8 24.8 3.5 4.9 15.5 10.2 0.4 3.9 17.5 1.6 3.3 0.6 0.2 1.9 0.0 3.9 5.7 48.4 35.5 0.0 4.1 8.1 2.3 3.2 0.0 1.2 0.2 1.3 14.6 1.8 1.7 2.0 9.0 2.1 0.8 0.5 0.0 8.5 0.1 35.9 0.1 1.6 31.9 6.5 12.5 38.6 70.4 12.6 4.1 0.0 0.0 9.5 0.4 0.1 0.4 1.0 1.9 2.3 0.6 2.0 5.7 2.4 2.1 2.1 15.2 1.4 3.9 5.3 1.0 0.1 3.0 4.6 8.3 0.8 22.8 1.2 1.1 1.7 0.5 5.5 0.2 7.8 0.1 0.5 17.5 0.5 0.7 0.2 0.3 0.5 0.2 0.7 0.4 0.6 0.3 0.4 3.3 1.6 3.9 0.4 0.2 26.8 35.5 12.1 21.5 25.0 18.3 22.4 18.4 22.7 25.7 20.8 34.5 0.0 4.1 4.1 34.9 54.9 22.9 2.7 13.6 34.9 7.9 0.1 10.0 12.8 12.0 47.2 0.5 0.0 20.9 0.2 8.0 9.4 2.3 11.6 7.2 271.7 5.2 38.6 5.0 48.4 4.9 4.7 18.6 3.6 5.5 8.3 22.7 1.4 4.2 4.4 15.4 12.9 6.9 3.2 1.1 3.0 0.2 1.3 1.2 5.8 RPS6KA3 "CLS, HU-3, MRX19, RSK, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 19.7 12.5 9.9 23.0 12.5 8.2 16.5 15.2 12.1 11.4 23.2 4.4 22.1 13.7 12.4 10.1 13.6 12.7 15.7 21.3 9.7 8.8 14.1 25.8 21.6 34.0 9.9 10.0 12.7 14.0 36.6 9.8 11.0 10.2 14.5 18.8 7.7 14.3 11.3 45.2 11.7 23.7 16.1 11.7 25.8 11.8 4.8 9.7 29.4 13.5 15.0 18.2 20.3 19.0 4.2 8.6 12.5 6.9 8.3 11.3 2.7 12.9 22.7 8.6 4.4 8.4 14.8 2.6 11.2 17.1 8.4 11.6 25.7 16.7 8.5 3.9 11.8 12.3 9.2 9.8 9.5 15.7 7.1 7.8 10.0 14.3 69.0 8.6 19.5 10.4 9.4 7.6 13.2 16.7 7.4 30.4 9.0 6.6 24.4 8.8 6.1 12.6 6.0 6.2 16.9 13.7 6.7 18.2 9.8 7.3 10.9 4.0 3.9 15.1 4.6 16.4 11.2 0.0 5.8 16.9 9.2 6.4 29.1 6.3 19.5 11.9 9.5 17.4 9.7 21.7 12.5 4.7 9.5 6.3 6.9 11.3 2.9 7.3 6.9 7.0 4.2 5.0 6.0 7.5 8.3 6.9 8.6 3.5 2.7 9.9 12.5 15.2 12.1 9.7 8.8 9.9 10.0 10.2 9.7 41.7 68.2 18.2 31.8 48.3 33.6 19.4 38.2 21.4 51.2 15.7 21.6 3.3 3.3 23.3 0.1 48.1 43.4 0.0 26.0 5.7 28.8 47.0 42.8 61.1 20.6 12.7 24.0 29.4 46.1 1.1 12.0 60.4 35.4 20.8 53.4 26.6 30.0 46.0 19.8 23.7 8.7 19.4 35.0 3.3 7.7 48.6 3.0 56.7 46.1 54.2 RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cytotrophoblasts: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 12.6" "Lineage enriched" "Detected in many" 4 "dendritic cells: 12.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol No No Nucleoplasm Cytosol "CAB008649: AB_1619460, HPA023225: AB_1854144" "unprognostic (2.30e-1)" "unprognostic (7.05e-2)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.47e-2)" "prognostic unfavorable (8.17e-4)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.45e-1)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-3)" "unprognostic (1.98e-2)" "unprognostic (3.93e-3)" "unprognostic (5.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" 14.9 9.1 13.3 15.7 17.1 13.2 7.6 37.6 22.7 7.7 12.4 13.1 5.8 14.0 11.0 6.9 18.5 8.1 10.5 7.8 10.9 10.1 8.7 9.6 10.9 15.0 16.7 9.9 6.5 9.2 5.7 4.7 16.6 9.8 8.3 8.4 10.0 10.9 8.9 16.3 17.3 15.4 9.8 11.5 22.2 18.3 3.3 13.5 7.6 6.7 16.7 16.4 9.7 8.8 0.5 12.6 1.4 3.0 0.3 1.0 2.1 28.1 15.8 2.3 5.7 5.1 4.8 32.6 15.0 7.9 11.8 5.8 15.6 14.8 2.9 17.5 8.6 15.0 26.1 2.7 12.2 5.8 8.9 5.3 6.6 13.5 7.9 5.1 6.7 12.4 4.7 11.5 10.0 8.2 4.2 7.1 5.4 2.7 4.1 5.9 25.8 6.0 10.5 2.5 10.9 33.3 11.8 9.4 9.4 8.1 13.0 3.4 2.7 15.5 9.5 13.0 3.4 11.1 8.3 14.1 16.1 20.2 29.0 13.3 4.9 3.8 2.9 10.6 7.7 8.1 1.1 3.0 1.4 0.9 2.4 1.0 0.5 0.7 0.7 2.7 0.4 0.4 0.4 0.2 0.3 1.4 12.6 0.6 2.1 13.3 17.1 37.6 22.7 10.9 10.1 16.7 9.9 9.8 13.5 3.0 4.0 5.7 4.6 10.8 6.3 11.8 5.1 0.0 1.2 3.5 3.9 60.8 5.0 13.7 0.2 7.4 17.0 0.0 21.8 31.5 9.1 7.1 19.5 6.4 26.9 7.9 8.1 11.6 29.2 0.7 10.3 15.3 8.5 12.6 11.6 3.1 40.7 10.7 6.3 7.3 2.0 0.0 9.2 0.7 7.2 9.4 39.0 8.7 13.9 8.5 RPS6KA5 "MSK1, RLPK" ENSG00000100784 "Ribosomal protein S6 kinase A5" O75582 14 90847862-91060636 "Enzymes, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "granulocytes: 86.9;Syncytiotrophoblasts: 93.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 30.1;SK-BR-3: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001274, HPA001780, CAB025458" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "CAB025458: , HPA001274: AB_1079417, HPA001780: AB_2666432" "unprognostic (3.05e-2)" "unprognostic (2.19e-3)" "unprognostic (4.27e-4)" "unprognostic (1.98e-3)" "unprognostic (4.79e-2)" "unprognostic (4.20e-4)" "unprognostic (3.70e-2)" "unprognostic (5.80e-4)" "unprognostic (6.70e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-4)" "unprognostic (5.73e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.75e-1)" 4.9 2.4 8.3 13.0 21.6 5.8 16.3 32.9 12.2 7.0 11.0 12.0 4.2 9.3 11.8 2.6 11.9 8.9 6.7 6.1 9.0 7.9 4.5 4.1 6.1 7.3 12.8 9.7 10.2 4.9 12.0 6.9 14.9 11.0 8.0 11.7 2.8 8.7 9.9 14.3 6.6 9.8 19.4 17.1 7.4 9.8 5.2 13.7 4.8 8.6 7.8 7.7 11.6 7.3 5.8 2.5 20.0 3.2 8.4 7.1 2.2 1.2 1.7 2.0 1.3 0.0 0.4 8.7 0.7 1.1 2.3 3.4 0.9 2.3 5.9 2.5 2.2 1.6 3.8 1.7 1.7 4.8 0.9 3.1 5.9 1.7 0.2 0.0 5.8 30.1 0.5 3.6 1.4 1.1 0.5 2.5 4.1 0.6 6.7 2.3 2.5 1.8 2.9 0.6 3.7 2.7 3.2 9.6 3.0 2.5 2.2 10.1 3.2 2.5 15.1 8.5 1.8 2.9 1.9 0.5 0.7 1.3 0.6 2.9 2.9 2.8 5.1 1.4 4.3 9.5 10.5 2.7 7.8 3.6 2.1 5.9 4.4 4.8 3.5 2.5 5.8 5.6 3.0 20.0 8.4 3.2 1.0 7.1 2.2 8.3 21.6 32.9 12.2 9.0 7.9 12.8 9.7 11.0 13.7 17.9 27.4 40.7 37.9 35.8 29.4 14.1 12.7 37.5 29.6 7.0 15.7 31.0 0.0 8.9 5.5 19.6 27.6 0.0 4.6 4.7 13.2 25.2 86.9 6.8 6.4 25.4 15.6 14.1 16.1 2.1 13.0 16.9 18.6 2.8 17.9 12.9 3.0 11.5 11.0 2.8 29.2 12.9 27.6 13.1 23.7 40.5 93.5 39.5 18.8 42.3 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84187907 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 20.7" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 19.9;Collecting duct cells: 17.4;Cone photoreceptor cells: 23.6;Intestinal endocrine cells: 24.0;Rod photoreceptor cells: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 11.0;PC-3: 11.9;RH-30: 14.6;SH-SY5Y: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.7 2.9 5.9 1.0 12.2 0.0 2.3 4.7 5.1 3.1 4.5 1.1 20.7 1.7 2.7 4.0 1.5 4.0 1.9 1.2 5.1 2.9 9.2 0.9 0.8 0.2 1.5 3.3 4.9 3.4 13.5 9.1 0.5 4.4 4.3 3.7 1.5 3.0 15.0 1.4 2.3 2.0 1.7 1.0 0.6 2.4 2.6 2.7 0.8 14.5 0.9 0.6 3.3 2.3 1.2 0.8 2.4 0.5 0.7 2.8 0.1 0.0 3.7 3.6 0.0 3.4 3.4 0.0 7.7 4.1 3.4 2.9 2.8 3.0 0.0 0.0 4.1 0.0 0.1 9.1 6.1 8.1 0.0 4.6 0.0 0.1 0.0 3.1 0.0 0.0 1.9 0.0 0.0 3.8 3.8 0.8 0.0 0.0 0.2 2.7 0.0 1.3 0.1 11.0 0.0 11.9 0.0 14.6 0.0 0.6 8.5 0.0 11.7 0.0 4.2 0.0 5.2 2.0 0.0 0.0 0.1 4.4 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 2.4 0.4 0.5 0.5 0.3 0.4 1.2 0.4 0.7 0.8 0.6 0.4 0.4 1.1 0.7 0.5 0.4 2.8 0.1 5.9 12.2 4.7 5.1 5.1 2.9 1.5 3.3 4.4 2.7 8.9 2.4 2.0 4.4 0.2 19.9 2.0 12.7 6.7 3.4 17.4 23.6 2.1 1.7 0.4 0.4 0.6 3.4 0.0 1.1 0.6 0.3 7.4 0.0 1.5 0.2 1.6 24.0 1.3 0.0 0.0 4.0 0.0 0.0 0.0 5.0 2.8 1.3 2.9 5.6 3.3 18.2 0.0 0.6 3.7 6.3 0.4 1.9 0.0 5.3 4.2 RPS6KB1 "p70(S6K)-alpha, PS6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "MCF7: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB003838: AB_562325, CAB018346: AB_632156, HPA039442: AB_2676510" "unprognostic (2.25e-1)" "unprognostic (4.52e-2)" "unprognostic (1.91e-3)" "unprognostic (1.35e-2)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.70e-1)" "unprognostic (5.86e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.09e-7)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" "unprognostic (1.52e-3)" 18.4 18.3 16.6 23.2 19.5 20.5 18.4 25.7 24.2 18.1 18.2 13.1 18.4 13.1 19.6 16.5 25.4 14.5 14.9 14.2 15.7 12.6 13.5 20.0 14.8 17.3 20.3 17.5 21.6 22.3 24.5 18.9 20.3 17.6 16.7 15.0 10.1 17.3 21.5 50.3 15.8 14.1 19.3 19.8 17.6 17.5 10.7 20.0 17.8 16.8 18.4 22.0 18.5 20.8 8.9 12.8 25.9 11.1 9.4 13.5 8.3 10.9 10.6 9.1 8.6 6.3 9.2 6.9 10.1 9.4 8.9 10.0 8.7 5.5 13.2 12.6 8.4 10.7 5.7 12.0 9.1 14.4 7.3 13.4 9.0 6.9 9.9 9.3 13.9 9.1 9.4 7.0 10.3 7.6 7.4 11.6 8.5 11.9 8.5 6.6 76.1 16.5 5.9 6.1 9.6 8.2 9.8 15.4 12.3 7.4 8.1 6.6 8.0 8.5 5.0 5.4 11.0 9.8 7.7 10.0 8.7 14.5 7.0 13.4 15.4 13.0 14.9 6.6 8.6 6.9 25.9 10.1 9.0 11.4 10.2 13.5 8.9 10.5 13.0 12.8 8.6 12.3 12.9 10.0 9.4 11.1 8.0 9.5 8.3 16.6 19.5 25.7 24.2 15.7 12.6 20.3 17.5 17.6 20.0 20.8 32.2 20.1 17.7 29.3 16.3 13.7 17.8 25.4 38.7 3.5 17.7 20.8 3.3 10.9 2.6 18.8 10.1 0.0 14.1 15.1 21.8 21.4 22.0 12.4 10.6 17.5 12.7 11.1 14.8 2.1 14.7 18.0 10.1 16.2 16.1 11.9 13.7 10.5 17.0 7.2 18.5 25.8 22.8 11.1 13.1 28.0 25.5 20.3 13.4 24.3 RPS6KB2 "KLS, P70-BETA, p70S6Kb, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435408 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol NA NA Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" 8.7 14.1 8.5 12.8 9.2 18.0 11.2 12.9 11.5 13.1 13.0 12.5 12.3 19.8 10.2 10.1 36.1 11.0 10.7 10.7 8.8 4.2 11.3 27.8 10.7 12.0 11.4 8.7 9.5 18.7 9.6 11.7 13.8 8.7 17.2 9.9 11.7 18.1 15.8 25.0 41.4 17.7 8.8 7.6 18.6 17.1 7.5 8.8 21.8 11.4 28.6 21.8 10.1 15.6 15.7 27.1 16.4 28.3 17.8 20.7 20.2 21.3 16.2 8.9 15.0 4.1 8.0 11.7 10.3 13.0 19.4 13.5 25.3 14.4 7.9 18.0 10.1 12.1 16.0 10.0 15.8 7.8 13.6 26.6 12.7 20.7 20.6 14.0 16.1 15.7 10.1 16.6 10.2 10.5 4.9 14.4 21.0 20.4 21.2 9.7 32.8 24.7 25.3 9.5 31.4 20.9 18.3 12.3 37.5 9.0 12.3 13.4 14.4 10.7 29.7 22.1 5.4 34.9 13.4 6.0 10.1 10.8 24.5 11.5 19.0 15.6 12.7 16.6 10.1 12.7 9.7 22.6 16.4 15.7 25.2 15.9 15.7 14.9 15.3 27.1 14.3 10.9 11.9 15.1 17.8 28.3 18.7 20.7 20.2 8.5 9.2 12.9 11.5 8.8 4.2 11.4 8.7 8.7 8.8 8.9 18.6 37.3 23.0 44.3 24.7 1.1 40.8 4.0 9.1 7.0 9.8 63.1 36.5 40.3 10.4 15.8 75.3 23.3 56.9 74.1 22.2 38.7 27.6 48.6 53.5 31.8 44.4 16.0 37.6 22.0 18.7 27.9 18.6 55.1 53.9 19.0 40.6 63.3 16.3 27.7 26.0 19.4 22.7 13.1 13.8 55.7 86.6 44.9 49.3 30.7 RPS6KC1 humS6PKh1 ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274773 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Supported Endosomes,Lysosomes NA NA "Endosomes, Lysosomes" "HPA026531: AB_10601497, HPA031565: AB_2673935" "unprognostic (3.90e-2)" "unprognostic (5.90e-2)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (9.81e-2)" "unprognostic (1.32e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (8.10e-2)" "unprognostic (5.48e-2)" "unprognostic (2.98e-2)" "unprognostic (4.44e-2)" 12.0 14.1 15.6 10.0 19.4 6.4 17.1 13.5 19.4 14.1 13.1 12.6 8.8 9.2 15.9 8.4 10.3 11.8 11.6 9.4 17.3 15.6 9.8 10.8 13.6 7.5 17.8 16.8 14.4 13.5 19.9 16.7 12.3 15.3 17.6 10.1 7.3 8.9 17.7 14.1 6.7 8.7 18.5 22.3 11.0 12.5 26.5 13.2 6.8 10.4 6.1 7.8 14.6 16.0 2.5 8.7 13.7 6.8 4.0 3.3 2.2 7.3 6.4 10.5 11.3 10.5 15.6 9.2 9.7 14.3 15.1 17.4 5.2 8.2 4.7 6.6 14.6 9.9 6.1 12.7 7.9 11.5 9.8 4.7 12.6 7.5 7.1 9.7 7.9 15.0 10.2 6.9 13.2 7.2 12.7 12.5 4.6 16.2 7.3 15.4 4.0 3.3 2.6 15.2 6.6 7.2 3.9 9.9 4.5 6.9 7.4 6.1 15.9 10.5 8.3 13.9 18.7 11.9 3.3 11.6 10.3 9.5 11.8 6.3 4.3 8.2 3.6 4.4 3.1 10.5 13.7 4.6 3.3 2.8 6.8 2.3 2.5 2.3 2.4 8.7 1.9 1.5 3.3 0.5 4.0 6.3 1.0 1.6 2.2 15.6 19.4 13.5 19.0 17.3 15.6 17.8 16.8 15.3 13.2 8.9 4.3 1.4 2.2 2.6 17.1 8.9 7.6 4.0 4.5 0.0 13.7 2.6 0.0 4.4 25.9 6.5 4.0 0.0 6.8 3.3 6.9 4.5 7.0 8.1 6.1 19.1 3.5 10.4 8.6 33.0 10.3 9.8 6.8 6.4 3.2 6.6 5.4 2.8 7.1 4.6 18.9 12.9 5.1 13.4 17.2 3.9 3.2 5.1 3.7 2.6 RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266207-100292769 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm NA NA 8700 Nucleoplasm "HPA027982: AB_10601769, HPA027990: AB_2672452, HPA028151: AB_10602099, HPA028331: " "unprognostic (4.79e-2)" "unprognostic (1.17e-2)" "unprognostic (3.97e-2)" "unprognostic (3.82e-2)" "unprognostic (6.76e-2)" "unprognostic (4.12e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (9.55e-3)" "unprognostic (3.64e-2)" "unprognostic (1.12e-2)" "unprognostic (2.46e-1)" "unprognostic (8.09e-3)" "unprognostic (3.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.94e-2)" 20.9 25.0 19.4 17.8 24.9 25.5 20.0 22.6 31.7 14.7 22.9 20.3 19.9 31.7 14.2 26.0 27.0 13.4 19.9 25.5 20.0 21.0 31.7 23.0 16.1 21.8 21.5 20.7 13.3 27.7 21.1 17.2 21.2 33.1 20.9 22.2 14.1 18.5 17.4 35.4 14.6 37.8 15.4 20.5 24.2 21.8 12.2 12.4 25.0 18.3 20.2 20.8 18.7 17.5 9.6 8.0 8.2 19.6 11.0 20.1 7.7 22.0 11.4 11.3 15.2 14.3 23.3 30.9 26.2 12.8 17.1 14.8 18.6 11.1 22.6 19.9 16.6 21.1 11.2 13.8 12.4 20.7 22.6 11.5 14.9 13.0 23.4 22.1 27.1 23.6 18.9 19.6 22.3 29.9 17.0 21.2 16.5 25.6 34.5 25.8 7.3 13.9 21.1 17.3 15.7 22.1 10.0 20.2 9.9 21.0 18.1 9.1 11.4 16.9 24.5 35.8 18.5 5.3 34.8 18.4 16.2 11.3 25.2 31.4 20.0 20.1 18.1 34.0 23.6 9.6 8.2 9.1 7.5 10.8 11.3 13.8 9.6 10.0 12.8 8.0 7.1 9.3 10.5 4.4 11.0 19.6 7.6 20.1 7.7 19.4 24.9 22.6 31.7 20.0 21.0 21.5 20.7 33.1 12.4 6.0 14.4 26.1 13.0 12.0 22.2 49.6 7.6 13.4 10.3 17.4 11.8 48.9 21.6 37.0 11.5 17.5 35.4 0.0 30.2 65.3 13.9 14.2 12.7 15.3 69.5 20.6 18.5 22.7 41.9 6.4 17.8 28.9 15.1 50.5 26.6 20.6 46.7 37.1 12.0 49.6 26.8 6.5 12.3 27.2 14.7 12.8 38.8 32.0 29.7 15.7 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Hepatocytes: 186.8;Kupffer cells: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 14.9;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 8 "granulocytes: 14.9;monocytes: 12.3" "Cell line enhanced" "Detected in many" "BEWO: 24.3;HaCaT: 27.4;RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 18.5 10.1 9.9 10.4 6.7 19.6 36.8 4.6 9.8 11.0 9.3 4.9 8.1 14.0 10.1 6.1 24.2 9.3 12.9 14.2 9.0 3.7 11.7 49.3 12.8 10.4 6.0 7.0 11.7 20.6 8.0 10.7 9.6 9.4 9.7 2.0 9.5 9.3 9.7 45.8 19.0 15.2 10.6 9.5 11.5 8.8 5.9 8.1 1.5 13.6 18.3 5.9 16.0 23.7 0.1 1.7 14.9 12.3 1.3 1.1 1.8 5.6 15.8 2.0 5.0 3.6 3.3 24.3 3.0 3.5 4.4 2.5 8.8 8.8 0.0 8.3 4.4 3.8 27.4 0.7 10.7 0.2 8.0 2.0 0.0 19.3 13.3 4.6 6.6 2.4 5.4 4.6 5.5 2.6 0.6 3.7 0.9 10.9 0.5 1.0 15.1 0.5 1.4 3.8 4.1 5.5 2.9 7.5 10.9 0.2 24.4 4.5 2.0 9.6 9.2 2.4 0.1 12.8 9.0 4.8 5.4 6.5 5.7 2.7 0.7 0.0 0.1 4.1 6.7 3.5 1.1 5.2 2.8 1.1 9.3 0.0 0.1 0.7 0.7 1.7 0.0 0.2 0.9 14.9 1.3 12.3 0.1 0.9 1.8 9.9 6.7 4.6 9.8 9.0 3.7 6.0 7.0 9.4 8.1 29.8 22.2 2.2 14.1 30.7 3.8 30.8 79.0 8.1 21.6 8.7 23.6 24.3 1.7 11.9 4.5 17.5 46.7 23.3 12.2 27.0 17.3 15.8 1.1 186.8 29.1 31.8 9.2 72.4 115.8 14.1 30.0 27.5 11.8 5.4 24.8 42.2 14.1 34.5 19.8 16.2 21.2 19.4 17.9 0.7 12.3 40.9 20.0 13.1 23.9 26.0 SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported Enhanced Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA041906: AB_2677735, HPA043552: AB_2678548" "unprognostic (9.69e-3)" "unprognostic (1.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.49e-8)" "unprognostic (9.86e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.15e-5)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.27e-1)" 20.1 17.8 26.7 22.8 30.5 24.0 18.6 21.9 45.9 23.6 50.1 17.6 21.6 14.0 30.2 13.1 27.5 21.3 17.1 22.5 21.2 23.9 14.6 16.0 19.2 30.6 20.4 34.6 19.0 14.4 28.0 13.9 26.8 24.3 20.2 27.3 20.9 15.7 28.6 24.1 19.0 20.1 38.5 15.9 25.8 30.5 60.2 16.2 32.7 37.5 17.2 37.5 33.0 25.8 19.1 22.3 22.8 19.0 35.2 41.3 29.4 36.2 39.8 62.5 29.8 21.5 25.3 21.2 44.9 39.2 50.7 62.0 34.2 24.2 43.7 17.7 36.0 26.9 17.3 64.0 28.3 55.2 36.6 46.5 42.5 26.9 39.0 23.7 47.0 26.5 18.8 14.6 27.7 29.9 20.0 48.5 31.5 50.5 22.1 47.8 29.1 30.8 129.8 31.2 39.3 21.3 48.5 41.9 17.9 22.7 43.0 24.7 27.2 46.0 31.7 27.1 35.8 25.9 28.7 25.2 26.7 30.7 17.5 48.2 27.6 80.2 62.1 18.8 39.1 39.0 22.8 19.0 10.4 23.0 16.9 24.8 19.1 29.0 23.2 22.3 15.7 41.3 31.3 7.9 35.2 11.3 15.0 33.5 29.4 26.7 30.5 21.9 45.9 21.2 23.9 20.4 34.6 24.3 16.2 8.9 16.0 34.0 28.7 22.8 17.8 18.6 7.6 4.0 10.3 12.2 5.9 57.7 10.0 35.8 11.1 31.4 10.5 23.3 30.4 80.2 33.8 28.6 15.0 17.4 48.9 19.1 18.5 20.3 19.0 12.8 14.4 20.0 43.9 71.3 22.5 18.0 30.8 14.4 17.7 11.5 15.0 51.8 35.6 95.2 109.0 21.5 48.1 33.2 28.3 25.8 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.3" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 54.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.3 8.7 8.9 10.4 11.3 18.0 7.8 12.2 14.1 9.7 9.3 13.8 6.6 8.2 11.7 9.5 9.9 9.4 8.2 8.0 9.6 8.5 6.8 7.8 7.9 9.1 9.7 9.0 11.6 8.4 16.3 13.8 10.4 9.6 9.1 9.8 8.8 11.3 8.5 10.5 11.6 8.9 10.3 8.9 8.3 9.0 50.3 9.9 17.1 8.8 6.9 11.9 9.9 9.5 5.8 6.8 15.6 8.5 3.5 6.2 3.5 20.5 11.4 21.5 17.3 14.3 9.9 23.6 13.2 12.9 20.5 16.2 27.0 8.6 17.3 11.9 14.8 10.7 14.5 23.7 13.6 21.3 9.6 15.2 17.1 10.3 21.0 17.2 14.8 13.6 9.3 10.2 27.0 17.0 10.8 16.3 14.6 20.7 12.8 17.1 23.0 20.5 11.7 22.2 12.2 12.8 14.2 17.7 11.5 10.9 18.3 11.4 13.7 13.9 13.2 8.2 14.2 9.9 10.2 13.9 19.8 21.6 18.4 13.9 18.0 17.7 20.6 16.3 10.1 12.7 2.4 4.2 4.8 6.2 3.0 4.8 2.4 4.4 4.0 3.7 5.8 3.2 3.5 15.6 3.5 8.5 6.8 3.0 3.5 8.9 11.3 12.2 14.1 9.6 8.5 9.7 9.0 9.6 9.9 0.0 10.4 3.2 1.9 7.0 4.2 11.9 5.1 4.0 1.2 1.8 7.9 9.4 0.0 3.7 54.0 5.3 6.6 0.0 4.1 10.7 4.7 4.4 1.1 5.1 6.6 7.9 6.4 7.4 11.0 34.3 7.8 5.7 5.0 1.0 6.5 4.1 4.3 7.0 7.8 2.9 5.8 6.5 5.0 17.9 16.6 9.2 16.1 5.0 6.6 3.0 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28292519-28323849 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 31.1;lymphoid tissue: 22.1;skeletal muscle: 39.6" "Cell type enriched" "Detected in many" 8 "Cone photoreceptor cells: 76.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.3;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.4;naive CD8 T-cell: 3.0;NK-cell: 1.4;T-reg: 1.4" "Group enriched" "Detected in many" 10 "NK-cells: 1.4;T-cells: 4.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;AN3-CA: 11.0;NTERA-2: 15.8;REH: 16.7;SCLC-21H: 24.3;SH-SY5Y: 22.9" "Region enriched" "Detected in all" 5 "cerebellum: 306.7" NA NA "unprognostic (5.15e-2)" "prognostic favorable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.9 2.0 8.0 1.8 7.3 2.0 1.7 31.1 17.5 1.7 1.2 1.5 0.0 1.1 1.9 1.3 1.5 1.6 1.0 1.8 9.9 5.6 1.6 0.9 1.8 2.7 6.0 4.0 1.1 2.7 4.2 4.1 0.8 8.3 2.6 1.2 1.4 3.8 1.0 39.6 1.4 1.1 0.9 3.1 2.8 1.6 2.3 3.1 22.1 2.6 0.0 1.7 1.2 0.3 0.2 0.2 0.2 0.1 1.4 4.3 0.4 0.1 0.2 15.3 11.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.7 0.3 0.1 0.0 0.3 0.3 4.6 0.1 0.0 1.5 0.5 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.1 5.8 0.0 1.0 0.0 1.8 7.0 0.1 15.8 1.0 0.1 16.7 0.8 0.1 0.1 0.9 24.3 22.9 0.4 1.4 0.2 1.9 1.7 0.0 0.4 0.0 2.4 0.2 0.1 0.2 0.0 0.2 0.1 0.2 0.9 0.2 0.1 0.1 4.3 0.0 1.4 0.0 1.2 2.4 0.0 0.2 1.4 3.0 0.1 1.4 0.1 0.2 1.4 0.4 8.0 7.3 31.1 17.5 9.9 5.6 6.0 4.0 8.3 3.1 3.0 0.3 0.0 0.8 0.6 9.4 3.1 2.5 2.7 3.4 0.0 76.6 0.0 1.7 6.1 1.0 0.0 0.0 0.0 4.8 0.0 0.4 1.5 0.0 0.2 0.1 0.0 5.8 0.0 0.0 3.1 0.6 0.0 0.0 0.0 0.3 4.2 4.7 0.0 0.0 0.5 2.7 0.0 0.3 1.4 2.3 0.1 0.1 2.5 0.8 0.3 SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060889-238099413 "Enzymes, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 12 "Early spermatids: 82.6;Late spermatids: 106.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020190, HPA055760" Uncertain Enhanced "Golgi apparatus" NA NA 110000 "Golgi apparatus" "HPA020190: , HPA055760: AB_2682910" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (8.65e-5)" "unprognostic (8.96e-2)" "unprognostic (9.85e-3)" "unprognostic (1.14e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-2)" "unprognostic (8.38e-2)" "unprognostic (3.98e-3)" "unprognostic (1.03e-2)" "unprognostic (1.02e-3)" "unprognostic (3.73e-1)" "unprognostic (4.37e-2)" "unprognostic (2.50e-3)" "unprognostic (1.98e-1)" 4.1 3.8 6.0 6.3 7.4 5.3 3.6 10.2 7.4 4.3 6.3 11.1 5.7 9.8 8.4 8.3 4.5 4.6 5.4 6.5 7.3 6.8 9.9 24.1 4.0 6.5 9.6 4.7 6.3 22.7 5.2 5.1 2.6 6.6 5.0 4.3 6.4 4.5 5.6 5.1 2.8 9.6 5.1 9.4 5.6 3.9 15.3 6.1 8.9 8.1 6.3 5.3 4.6 4.0 5.0 5.7 6.9 5.6 4.2 8.1 4.3 5.7 9.7 6.2 16.6 5.0 3.4 12.6 5.8 2.9 6.2 7.6 6.4 4.7 9.6 1.7 3.3 19.9 8.4 24.3 12.4 5.9 10.9 21.8 11.1 13.0 22.0 9.4 9.2 9.6 3.8 6.1 11.6 13.3 2.6 11.5 13.3 19.3 2.7 6.3 8.6 9.1 16.9 20.1 8.0 8.1 10.7 12.0 9.5 5.9 2.0 7.1 15.1 6.4 10.3 10.4 4.8 3.2 13.6 4.9 9.4 6.1 12.4 12.4 6.8 6.2 4.8 5.8 18.7 7.4 2.0 5.3 6.9 4.7 4.3 3.7 5.0 5.7 8.1 5.7 3.5 4.3 4.2 0.9 4.2 5.6 1.2 5.3 4.3 6.0 7.4 10.2 7.4 7.3 6.8 9.6 4.7 6.6 6.1 0.0 0.0 3.7 1.9 1.4 5.3 2.4 0.0 1.4 0.0 0.0 7.9 1.1 3.3 4.4 82.6 2.7 2.1 0.0 3.2 1.4 1.9 1.0 0.0 2.4 3.4 6.4 2.4 1.3 0.0 106.4 2.8 2.0 1.7 2.8 2.6 2.3 2.7 5.8 0.0 1.7 6.1 0.0 1.7 6.0 4.8 1.4 0.6 2.2 2.8 1.4 SETD5 FLJ10707 ENSG00000168137 "SET domain containing 5" Q9C0A6 3 9397615-9479240 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Autism, Autism spectrum disorder, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017093, HPA035574" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "CAB017093: , HPA035574: AB_2674681" "unprognostic (6.46e-2)" "unprognostic (1.64e-1)" "unprognostic (3.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.22e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.21e-4)" "unprognostic (5.52e-2)" "unprognostic (2.29e-1)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (4.04e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (6.65e-2)" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (5.15e-3)" 18.9 21.9 33.1 18.2 29.1 13.2 40.9 58.0 38.9 21.7 20.7 15.4 22.1 14.0 24.0 27.0 20.7 22.0 18.4 18.3 29.6 13.8 15.4 22.1 26.5 29.8 23.0 30.1 29.7 22.7 25.6 31.4 23.0 25.1 20.6 20.4 16.7 22.3 22.7 16.6 29.0 19.8 24.1 22.8 22.5 18.7 21.3 26.6 21.0 25.9 14.8 24.2 20.4 37.5 3.7 4.0 4.7 2.0 4.3 4.1 1.0 9.9 12.0 24.7 11.2 14.6 15.2 59.0 9.8 13.3 14.3 16.5 11.9 12.4 21.7 5.9 14.3 12.6 8.3 23.0 13.0 15.8 15.3 11.4 21.2 20.2 11.0 14.9 16.2 14.1 14.7 21.2 21.6 25.7 14.8 15.1 15.4 20.8 14.3 12.2 14.6 14.3 13.5 18.7 7.6 9.7 16.6 19.5 9.6 11.2 16.1 9.9 15.4 14.3 11.8 8.9 23.0 15.8 11.9 17.9 15.1 17.3 8.1 11.7 10.4 13.0 36.2 10.8 11.7 14.1 2.3 2.0 1.7 3.8 1.2 2.5 3.4 2.5 4.1 1.3 3.7 2.4 2.2 4.7 4.3 1.4 4.0 1.0 1.0 33.1 29.1 58.0 38.9 29.6 13.8 23.0 30.1 25.1 26.6 38.7 45.3 34.4 46.5 83.5 109.6 20.7 48.4 56.2 59.1 40.1 108.0 31.2 3.3 31.7 6.2 57.1 35.1 0.0 29.5 33.8 55.5 67.5 46.2 41.4 21.1 52.4 60.0 57.1 28.8 7.5 61.9 31.1 42.2 30.7 47.0 38.4 36.6 45.6 50.5 9.8 62.8 12.9 58.0 37.5 39.3 79.9 47.9 50.7 42.2 63.9 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 141.3" "Cell type enhanced" "Detected in many" 5 "Ito cells: 455.4;Syncytiotrophoblasts: 484.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;eosinophil: 45.9;neutrophil: 26.2" "Group enriched" "Detected in many" 7 "granulocytes: 45.9;monocytes: 11.7" "Cell line enhanced" "Detected in many" "HHSteC: 51.2;RPTEC TERT1: 78.5;SK-MEL-30: 50.9;TIME: 61.1;U-266/84: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" NA NA "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: AB_2681407" "unprognostic (2.05e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 45.6 35.5 16.8 12.8 43.2 15.8 22.9 10.6 25.0 18.4 62.3 51.7 10.8 14.2 14.9 11.2 30.0 16.1 47.8 12.5 22.9 9.6 37.5 51.1 31.2 8.4 48.8 16.6 47.2 47.8 141.3 4.7 19.2 28.3 18.3 11.3 45.8 26.2 18.4 12.4 25.8 131.8 13.6 40.3 7.6 31.1 12.2 50.1 6.2 22.3 24.8 20.4 26.1 31.7 0.6 4.0 45.9 11.7 0.9 0.7 3.1 0.6 1.1 0.7 0.0 8.8 2.2 1.0 12.6 26.3 16.5 13.5 1.9 1.7 2.1 1.9 13.0 8.1 0.4 1.1 2.0 12.2 0.0 0.5 0.1 31.4 1.4 51.2 0.1 1.1 13.2 12.6 16.2 21.0 6.6 27.6 0.3 4.0 32.0 5.9 0.1 0.1 0.4 0.8 3.2 1.3 0.4 1.5 0.2 78.5 0.2 0.3 3.1 39.6 0.1 50.9 7.6 0.1 0.3 61.1 4.8 2.1 29.5 2.7 6.0 56.0 6.5 4.5 1.9 6.5 0.6 11.7 45.9 0.2 6.8 0.5 0.6 0.4 0.2 4.0 0.4 0.5 0.6 26.2 0.9 3.7 0.2 0.7 3.1 16.8 43.2 10.6 25.0 22.9 9.6 48.8 16.6 28.3 50.1 35.7 233.2 40.3 98.2 162.8 10.8 19.4 96.8 24.1 99.0 64.6 33.4 39.9 18.3 60.3 7.2 107.9 230.9 0.0 151.5 27.8 58.7 45.7 257.3 17.5 283.4 0.0 10.2 455.4 148.5 5.6 14.1 322.4 254.8 6.4 46.9 4.3 52.7 129.6 14.9 92.1 28.6 12.9 39.1 48.4 7.5 101.6 484.9 9.6 6.4 68.4 SGK2 ENSG00000101049 "SGK2, serine/threonine kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.1;kidney: 39.1;liver: 32.9" "Cell type enhanced" "Detected in many" 15 "Distal tubular cells: 64.6;Enterocytes: 26.9;Hepatocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 10.3;CAPAN-2: 8.0;Hep G2: 10.4;OE19: 34.0;RPTEC TERT1: 14.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 11.4 0.7 2.8 4.3 9.9 0.2 3.1 1.0 10.2 1.4 21.3 33.1 0.9 17.8 1.0 19.7 0.7 1.6 7.9 0.7 4.3 2.5 39.1 32.9 0.6 0.5 6.9 5.1 3.2 14.1 0.5 1.7 0.5 13.7 1.4 23.4 0.0 0.9 1.8 0.4 3.2 20.7 1.0 14.2 0.7 11.9 1.0 6.0 0.0 1.0 0.2 0.2 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.5 8.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 10.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 34.0 0.0 0.0 0.0 0.0 14.7 1.7 0.1 0.4 0.0 0.7 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 9.9 1.0 10.2 4.3 2.5 6.9 5.1 13.7 6.0 0.0 0.0 0.0 0.1 0.1 0.8 2.2 12.7 0.0 0.0 10.4 0.0 3.4 64.6 3.9 0.1 0.1 26.9 0.0 5.4 1.0 0.2 0.1 0.0 26.9 0.6 6.4 1.7 1.3 1.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 2.6 8.4 0.4 15.7 0.8 0.0 0.0 0.0 0.2 0.1 14.3 0.0 5.9 0.1 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66667596-66862022 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006699, HPA027146" Supported Supported Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 6.5 5.9 13.9 8.7 20.9 7.7 23.9 9.8 14.8 12.0 10.0 24.0 8.7 8.6 8.0 10.3 7.6 7.8 7.8 5.4 16.1 10.2 14.9 13.6 9.9 8.5 28.8 9.3 9.8 15.6 29.2 14.8 5.9 14.6 7.8 10.7 17.2 7.0 7.7 6.1 12.4 10.8 6.0 32.8 8.2 7.2 8.9 21.9 8.3 17.3 4.3 6.8 6.1 8.0 5.8 13.8 21.4 15.7 6.9 13.3 8.0 11.6 3.0 0.5 1.9 3.5 7.0 6.5 7.4 7.1 4.1 4.3 5.3 7.8 8.8 1.8 8.1 11.0 3.8 6.1 4.3 5.1 4.9 10.3 7.9 2.2 5.2 3.5 7.1 9.4 3.3 3.9 1.9 6.8 3.8 6.5 7.0 1.5 4.2 7.7 1.8 5.6 4.4 1.7 6.7 4.1 9.8 4.4 5.9 5.4 2.6 2.5 2.0 3.3 5.0 11.2 5.2 23.5 14.2 7.7 3.9 3.4 3.3 2.8 5.2 10.1 10.1 4.5 12.0 4.0 21.4 15.7 6.2 8.1 9.3 13.3 3.7 8.4 8.5 13.8 5.8 9.0 6.9 2.5 6.9 4.4 7.7 5.3 8.0 13.9 20.9 9.8 14.8 16.1 10.2 28.8 9.3 14.6 21.9 6.0 22.6 7.8 5.6 11.7 1.7 5.6 7.6 16.0 11.4 10.4 17.7 7.0 13.3 5.8 0.6 9.8 10.5 0.0 15.8 1.2 4.5 8.9 14.0 18.3 21.3 0.0 15.5 17.2 34.8 1.1 3.7 32.9 8.5 45.1 7.0 3.5 12.1 9.7 7.4 30.7 1.6 0.0 3.1 4.1 11.3 13.8 4.0 15.8 8.2 4.7 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094256-169271105 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 5.9;myeloid DC: 3.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 13 "dendritic cells: 3.4;monocytes: 8.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No Vesicles "Intermediate filaments" "HPA074783: AB_2732268" "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favorable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 15.2 4.8 13.8 7.2 11.8 3.7 11.1 2.5 12.7 7.5 17.2 15.9 10.8 15.7 6.8 7.2 7.1 6.9 19.7 7.8 17.8 9.3 14.6 9.6 11.3 3.7 13.0 10.9 11.9 12.0 5.2 7.8 8.6 10.3 17.2 16.0 10.7 20.9 10.7 16.2 6.8 17.2 8.8 11.7 4.5 27.6 7.0 11.3 0.9 23.1 7.6 5.5 9.4 6.3 0.4 3.4 0.0 8.5 0.3 0.0 0.7 7.3 6.1 5.6 16.1 6.0 7.6 7.2 20.5 9.9 15.2 7.1 6.1 8.9 0.0 1.0 21.2 4.1 4.9 4.5 8.0 16.9 0.0 2.6 4.3 14.0 3.2 13.7 1.5 0.1 4.5 4.4 13.0 10.4 19.4 9.4 1.6 0.0 0.0 14.1 3.0 1.5 1.4 2.8 9.5 5.3 2.2 1.8 0.3 7.0 5.8 4.2 5.1 5.1 8.0 2.0 2.5 2.6 0.6 8.4 7.2 5.6 12.0 7.2 0.5 0.0 0.0 8.2 1.5 8.6 0.0 1.4 0.0 0.0 5.9 0.0 0.4 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.3 8.5 0.2 0.0 0.7 13.8 11.8 2.5 12.7 17.8 9.3 13.0 10.9 10.3 11.3 59.6 33.6 6.2 32.4 30.5 2.1 5.2 45.9 34.8 45.5 26.2 0.0 9.8 10.0 35.2 4.4 11.2 52.9 0.0 55.1 19.0 14.9 71.6 10.3 7.6 6.5 0.0 30.1 8.6 6.5 3.1 11.2 7.5 3.3 1.8 26.8 11.3 54.5 27.9 11.3 13.3 0.9 64.7 42.1 2.3 7.5 11.0 11.0 0.0 28.8 55.9 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936579-146081791 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 40.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 7204.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basal ganglia: 11.5;cerebral cortex: 2.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.4;T-cells: 1.6" "Cell line enhanced" "Detected in many" "CACO-2: 34.6;GAMG: 15.3;hTERT-RPE1: 17.2" "Region enriched" "Detected in single" 14 "basal ganglia: 23.9" "Region enhanced" "Detected in some" "basal ganglia: 14.5" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm NA Yes Nucleoplasm "HPA035903: AB_10696515, HPA058119: AB_2683611" "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 2.6 0.6 1.2 6.2 11.5 0.0 2.9 0.2 2.9 6.4 19.1 0.4 0.4 9.2 2.9 2.2 22.2 3.6 40.8 23.5 0.8 0.3 0.8 4.6 1.9 0.0 0.3 1.1 1.0 14.3 0.0 3.3 0.3 0.1 2.2 8.5 0.9 16.9 1.0 21.7 33.1 21.4 1.2 0.5 0.2 11.9 6.4 0.6 0.6 3.8 19.6 16.1 0.9 10.0 0.0 1.4 0.3 0.1 0.0 1.6 0.3 10.2 2.8 0.1 0.6 0.0 0.0 0.0 0.1 0.8 2.1 0.8 34.6 9.5 0.0 5.4 0.4 15.3 9.5 0.0 11.2 2.0 0.1 0.1 0.0 4.1 4.6 0.6 0.0 0.0 0.1 6.0 3.2 7.6 17.2 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.8 8.5 0.7 0.0 0.1 0.0 4.4 1.0 0.0 0.0 0.6 0.2 0.2 0.5 3.3 0.0 4.9 0.4 8.9 0.7 3.3 0.0 0.0 0.0 5.5 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 1.6 0.7 1.4 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.8 0.3 1.2 11.5 0.2 2.9 0.8 0.3 0.3 1.1 0.1 0.6 14.9 2.9 0.0 4.5 48.9 0.6 414.9 2.5 2.7 2.3 1.8 0.0 0.0 0.0 6.5 1412.5 1.5 27.7 0.0 7.6 0.0 0.5 1.3 1.1 8.3 0.2 0.0 1.2 0.6 0.0 7204.3 23.9 0.0 8.5 1.0 12.2 1.9 13.6 17.5 32.5 0.6 0.0 12.9 1.4 32.0 16.2 43.7 0.0 0.0 27.1 6.4 SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129348-109504632 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 9.0;Horizontal cells: 9.5;Ito cells: 9.2;Sertoli cells: 12.9;Smooth muscle cells: 10.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HHSteC: 14.1;RPMI-8226: 13.4;TIME: 15.6;U-266/84: 18.2" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" 17.4 5.6 2.7 3.4 4.4 0.6 18.3 1.7 5.4 5.3 3.6 3.3 2.5 1.0 5.5 2.2 3.4 4.8 5.6 6.4 3.0 2.1 2.5 0.8 6.0 2.9 4.3 1.5 3.0 1.8 0.6 2.6 6.5 3.8 3.4 1.6 4.6 2.4 5.9 6.4 2.9 2.3 4.6 2.8 2.0 2.7 4.3 2.9 1.5 3.4 3.6 4.0 4.6 3.4 0.4 0.4 1.8 0.2 0.0 0.6 0.3 0.0 0.0 0.1 1.5 6.4 4.9 0.0 2.8 8.3 2.2 0.8 0.7 0.0 0.0 2.2 2.0 0.5 0.0 0.1 1.2 0.9 0.0 2.8 0.0 0.1 0.0 14.1 0.0 0.0 8.5 2.0 9.7 4.4 1.2 7.8 1.5 0.0 8.0 4.9 0.0 0.0 4.3 0.7 0.0 8.1 1.7 0.0 13.4 0.0 0.0 0.5 1.7 0.0 0.0 0.3 0.1 0.1 0.0 15.6 2.8 8.3 7.9 3.6 2.7 18.2 0.0 0.0 4.2 3.8 0.0 0.2 0.7 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.4 0.6 0.6 1.8 0.0 0.0 0.4 0.0 0.3 2.7 4.4 1.7 3.3 3.0 2.1 4.3 1.5 3.8 2.9 0.0 0.0 0.0 0.2 1.6 0.1 9.0 0.0 2.7 1.2 0.0 0.0 0.0 0.0 0.5 2.0 3.8 0.0 0.0 0.2 0.1 4.1 0.2 0.0 0.0 3.6 9.5 1.7 9.2 3.7 3.6 2.0 0.5 5.0 0.0 0.2 0.8 0.1 0.0 2.8 0.8 0.0 12.9 10.8 0.7 6.6 0.6 0.1 0.0 0.0 0.0 SHPRH "bA545I5.2, FLJ90837, KIAA2023" ENSG00000146414 "SNF2 histone linker PHD RING helicase" Q149N8 6 145864245-145964423 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Helicase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 198.3;Rod photoreceptor cells: 175.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034854, HPA044852" Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Nucleoplasm, Nuclear membrane, Cytosol" "HPA034854: AB_10964488, HPA044852: " "unprognostic (3.10e-2)" "unprognostic (4.46e-2)" "unprognostic (5.61e-3)" "unprognostic (1.53e-2)" "unprognostic (7.40e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (5.03e-1)" "unprognostic (7.90e-2)" "unprognostic (6.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (3.01e-1)" 10.9 7.3 8.3 11.0 10.0 5.5 10.4 38.0 11.5 10.6 8.0 4.5 10.8 6.0 14.1 9.2 8.5 9.8 6.7 7.2 7.2 4.2 8.4 6.5 7.1 9.0 7.6 5.9 18.8 8.7 11.4 19.7 6.6 8.5 8.3 7.4 7.3 10.2 13.7 11.4 13.9 8.2 11.0 10.3 8.8 8.5 10.7 8.7 8.4 12.5 7.2 8.0 10.7 11.5 6.7 4.8 4.4 2.4 3.4 4.3 1.2 3.0 2.3 11.7 6.8 5.4 5.8 5.6 3.6 2.9 4.5 5.8 5.3 2.1 10.6 4.5 2.7 3.5 5.2 7.1 5.1 5.9 4.7 8.1 10.7 5.3 4.4 4.0 22.4 6.7 4.0 5.9 4.2 6.2 4.4 4.8 7.6 14.8 6.0 3.8 2.7 14.4 8.3 7.8 5.0 4.1 10.4 18.1 3.6 6.1 3.0 9.6 6.7 6.4 5.9 4.0 8.4 3.1 10.8 5.3 2.9 5.4 5.6 4.2 4.9 7.0 12.7 3.0 9.6 4.4 1.6 2.3 4.4 4.3 2.4 3.7 3.9 3.6 2.9 2.7 6.7 4.1 3.3 0.1 3.4 2.4 4.8 3.3 1.2 8.3 10.0 38.0 11.5 7.2 4.2 7.6 5.9 8.5 8.7 26.8 18.9 20.8 15.3 18.8 113.2 15.9 17.8 12.0 23.9 21.0 198.3 12.7 6.6 15.4 8.3 19.7 10.0 0.0 11.1 5.8 14.4 13.4 12.7 14.8 10.2 89.0 18.5 14.1 21.8 5.1 46.9 15.5 13.5 15.4 14.3 57.4 13.0 10.5 32.2 4.5 175.4 71.1 21.7 76.9 67.5 17.2 5.5 20.3 15.0 9.6 SI ENSG00000090402 Sucrase-isomaltase P14410 3 164978898-165078495 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 123 "intestine: 181.4" "Group enriched" "Detected in some" 7 "Enterocytes: 48.7;Mucus-secreting cells: 79.9;Paneth cells: 46.3;Undifferentiated cells: 29.8" "Cancer enhanced" "Detected in some" "stomach cancer: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.9;CACO-2: 4.1;HeLa: 3.2;NB-4: 3.4;RPMI-8226: 4.9;SH-SY5Y: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011897 Enhanced NA NA "HPA011897: AB_1856840" "unprognostic (2.71e-2)" "unprognostic (1.62e-2)" "unprognostic (2.68e-1)" "unprognostic (2.05e-1)" "unprognostic (4.41e-2)" 0.1 0.1 0.1 1.4 0.1 0.0 0.1 0.1 0.1 0.1 93.3 0.0 0.0 94.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 5.4 0.0 0.1 0.0 0.1 0.1 181.4 0.0 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 79.9 0.0 0.0 46.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 29.8 0.0 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 56.7;Enterocytes: 65.0;Paneth cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 31.6;ASC TERT1: 32.9;HSkMC: 35.2;OE19: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 1800000 "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 9.0 12.3 9.0 6.7 13.4 1.9 8.2 8.2 16.8 7.0 46.7 15.7 7.3 16.8 5.9 17.8 10.2 9.9 8.4 23.0 10.3 17.6 42.5 28.3 10.7 2.8 18.2 8.1 5.1 11.2 32.4 13.1 7.8 31.4 10.7 51.7 9.9 15.9 8.3 17.3 6.7 25.5 5.4 19.9 7.9 9.3 5.6 8.1 1.9 46.1 11.1 7.0 9.8 4.7 2.7 4.1 8.6 5.8 1.2 4.3 3.2 3.0 4.7 2.8 12.1 31.6 32.9 7.4 5.8 8.2 1.5 0.9 3.6 21.0 1.9 8.5 7.2 3.3 5.9 4.4 6.4 1.5 8.7 1.3 2.9 1.5 3.8 14.9 0.5 2.7 35.2 8.7 3.9 6.0 20.6 10.5 3.8 2.4 13.1 5.0 5.5 0.2 1.3 1.8 32.8 9.8 1.1 0.1 3.2 18.0 4.3 1.0 1.8 15.8 6.5 2.7 8.8 12.7 2.8 11.6 8.4 1.6 9.3 1.4 3.5 2.6 0.4 3.0 1.6 3.4 8.6 5.6 0.3 1.9 4.2 2.2 2.4 3.1 2.0 4.1 2.7 4.3 3.4 1.2 1.2 5.8 2.5 2.2 3.2 9.0 13.4 8.2 16.8 10.3 17.6 18.2 8.1 31.4 8.1 17.9 47.6 2.2 5.0 2.9 6.2 56.7 17.8 12.0 9.1 34.9 0.0 6.7 8.3 9.3 7.8 5.8 65.0 0.0 3.4 7.5 3.3 9.8 1.1 26.0 4.0 4.8 13.9 10.4 3.2 9.8 2.8 2.8 3.3 4.6 27.5 2.3 6.8 57.5 1.1 21.4 1.6 0.0 6.6 12.8 9.1 4.5 5.6 1.0 46.6 6.5 SIAH1 hSIAH1 ENSG00000196470 "Siah E3 ubiquitin protein ligase 1" Q8IUQ4 16 48356364-48448402 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 102.6" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 161.7;Syncytiotrophoblasts: 624.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018724 Enhanced Uncertain Nucleoplasm,Mitochondria NA NA Mitochondria Nucleoplasm "CAB018724: AB_2188865" "unprognostic (7.08e-2)" "unprognostic (1.16e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-3)" "unprognostic (1.25e-2)" "unprognostic (7.93e-3)" "unprognostic (1.12e-2)" "unprognostic (9.22e-3)" "unprognostic (3.26e-1)" "unprognostic (8.02e-2)" "unprognostic (7.84e-3)" "unprognostic (7.67e-3)" "unprognostic (4.38e-2)" "unprognostic (4.00e-1)" "unprognostic (9.55e-2)" "unprognostic (1.26e-2)" 20.6 11.4 11.9 11.0 13.5 19.2 25.5 15.5 16.6 14.6 13.1 15.0 6.5 12.8 16.8 13.4 12.7 12.9 12.9 11.4 12.6 11.6 12.1 17.5 13.9 10.0 12.8 11.6 16.7 11.4 13.1 9.1 102.6 14.1 14.2 12.2 32.1 13.2 12.1 17.0 16.6 16.0 18.6 12.7 11.3 12.5 17.9 13.0 17.5 14.5 9.3 11.5 15.9 14.8 12.6 8.3 21.9 5.2 5.3 6.1 3.5 8.6 7.8 16.9 15.1 14.6 12.8 17.3 8.1 11.0 12.1 5.9 5.9 11.3 11.2 9.0 10.2 8.4 10.1 11.6 11.8 14.9 4.5 9.4 6.0 6.1 15.4 20.4 5.9 9.3 15.3 21.3 7.0 16.4 13.5 10.1 10.5 9.7 10.7 9.8 5.9 15.9 12.1 20.6 9.6 12.1 18.6 25.4 11.8 11.2 10.9 19.3 17.1 24.0 12.0 20.7 15.2 7.6 13.7 10.7 12.9 11.7 7.0 8.6 14.0 5.8 20.6 9.6 7.4 11.6 6.9 5.2 21.9 2.7 2.2 3.0 12.6 3.0 4.2 8.3 12.1 6.1 4.5 2.9 5.3 1.3 7.9 1.6 3.5 11.9 13.5 15.5 16.6 12.6 11.6 12.8 11.6 14.1 13.0 11.9 11.9 16.4 51.3 76.1 18.3 12.0 10.2 9.4 10.3 15.7 7.9 161.7 26.6 21.4 60.8 27.0 18.8 0.0 19.9 25.3 52.6 43.7 4.6 19.5 29.5 33.4 21.7 28.8 18.3 53.9 21.0 23.2 47.2 38.7 18.3 30.7 19.2 14.4 18.4 21.1 16.5 19.4 37.1 68.6 47.5 66.1 624.0 13.4 16.7 38.7 SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741127-150763477 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Syncytiotrophoblasts: 325.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB069930: AB_1217916, HPA061293: AB_2684470" "prognostic favorable (1.17e-4)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (9.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (6.26e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-2)" "unprognostic (5.56e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-2)" 9.6 48.0 7.6 11.8 10.3 22.7 23.5 10.9 17.2 30.0 10.5 8.4 20.3 7.9 23.5 13.9 28.8 14.9 11.0 10.7 7.2 7.3 8.4 35.5 11.8 19.1 9.9 7.5 19.0 14.6 6.4 8.1 31.4 7.9 18.8 9.2 8.3 11.2 21.7 8.3 19.3 9.5 17.4 9.4 16.9 12.0 8.7 8.6 23.6 11.4 10.6 25.1 22.7 25.6 3.0 3.1 10.0 2.7 1.6 3.6 1.1 16.9 4.2 3.3 6.6 11.3 8.5 13.3 7.1 8.2 8.6 10.4 8.6 7.6 9.4 10.4 7.3 7.2 10.5 8.8 6.3 8.1 7.9 6.3 18.5 5.1 28.4 16.2 10.2 5.5 7.7 14.7 5.1 11.7 6.8 6.6 18.6 4.6 37.4 5.3 20.3 18.6 5.2 10.7 15.8 8.4 13.7 7.1 33.9 5.4 5.9 12.7 6.0 5.3 5.0 12.5 7.8 33.4 15.4 4.6 5.9 5.3 12.8 9.5 44.5 16.9 13.2 5.6 14.7 3.0 9.5 2.7 10.0 2.1 1.5 3.2 2.5 3.6 3.2 2.4 3.0 1.9 1.9 5.9 1.6 1.5 3.1 2.0 1.1 7.6 10.3 10.9 17.2 7.2 7.3 9.9 7.5 7.9 8.6 6.0 3.7 47.8 71.4 130.4 40.0 14.9 15.3 17.4 7.9 21.0 35.3 144.9 11.6 5.6 2.0 9.2 26.2 46.7 5.7 18.3 47.9 44.4 10.3 47.4 28.4 33.4 36.8 16.5 64.5 1.5 40.9 27.9 42.2 16.2 31.8 33.5 8.9 10.5 29.0 13.0 2.2 12.9 39.1 0.5 6.6 124.5 325.6 52.4 29.9 65.9 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 62.8;Rod photoreceptor cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.9 4.0 7.0 7.5 34.8 10.3 4.1 5.2 7.5 4.0 4.6 13.4 6.4 4.7 7.3 6.1 4.7 8.4 5.4 3.9 5.2 3.5 2.3 5.1 3.5 6.6 7.5 4.9 3.3 10.0 5.8 5.8 7.6 8.0 4.7 4.7 4.7 6.9 6.2 2.8 5.1 4.5 2.4 5.0 3.9 6.9 7.4 5.6 8.9 5.4 3.3 7.7 7.7 3.1 3.1 6.6 7.7 4.0 6.5 8.8 5.3 5.6 7.1 2.0 1.5 9.9 2.8 7.0 5.9 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 17.9 32.3 9.1 6.7 13.1 14.4 16.6 22.9 13.4 11.4 15.7 62.8 3.5 5.0 7.1 12.4 18.0 9.5 46.7 6.7 4.1 14.4 5.8 9.2 34.2 4.8 30.2 17.3 9.8 12.4 9.7 10.6 8.6 18.6 2.8 10.2 13.3 9.2 8.6 13.8 20.7 60.3 0.0 13.7 3.2 5.9 10.5 4.3 7.4 9.9 6.5 SIK3 "FLJ12240, KIAA0999, L19, QSK" ENSG00000160584 "SIK family kinase 3" 11 116843402-117098437 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 106.0;Late spermatids: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045245, HPA048161" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "HPA045245: AB_2679270, HPA048161: AB_2680293" "unprognostic (3.19e-2)" "unprognostic (3.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.21e-2)" "unprognostic (1.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-2)" "unprognostic (1.28e-3)" "unprognostic (1.89e-1)" "prognostic favorable (1.12e-5)" "unprognostic (1.82e-1)" "unprognostic (6.85e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" 13.0 12.2 24.7 13.8 36.9 14.3 13.5 24.0 34.4 13.5 16.6 40.5 10.4 10.9 18.6 9.9 13.7 16.6 12.8 16.0 23.7 16.2 13.9 17.6 13.7 11.9 25.8 24.4 22.4 19.5 29.4 18.4 16.3 23.9 11.4 11.7 10.6 11.7 15.6 16.9 11.3 14.0 18.4 17.2 14.2 14.5 26.0 38.0 10.4 22.1 6.9 12.9 14.5 12.9 2.4 1.7 3.9 3.7 1.6 1.8 0.7 7.9 6.1 9.7 10.2 8.4 9.1 15.6 6.0 10.9 4.8 5.4 14.8 9.2 9.4 9.9 11.1 10.6 12.5 8.0 8.7 6.7 25.8 5.1 21.1 6.7 9.1 7.8 7.5 8.3 10.0 5.1 10.2 16.5 6.1 6.4 6.3 10.1 7.0 6.5 2.7 6.7 8.1 5.4 5.4 4.5 8.7 5.6 7.4 6.6 1.5 9.5 7.6 16.3 7.2 3.2 7.8 4.7 8.0 7.3 5.9 7.5 9.8 6.0 5.0 3.6 12.0 5.5 12.4 7.9 3.9 1.1 0.0 1.0 1.5 1.8 0.4 0.9 0.4 1.7 2.4 0.3 0.1 2.6 1.6 3.7 0.1 0.1 0.7 24.7 36.9 24.0 32.2 23.7 16.2 25.8 24.4 23.9 38.0 8.9 26.1 22.2 23.4 23.6 42.8 19.3 12.7 18.7 15.9 5.2 106.0 7.4 5.0 6.7 76.2 16.5 9.7 0.0 6.4 2.6 20.8 17.6 17.3 18.4 6.8 44.5 16.6 14.1 21.4 130.5 9.5 18.7 15.1 4.6 12.0 47.3 7.9 8.6 13.4 5.6 64.0 0.0 20.6 20.4 11.3 21.2 24.8 25.9 10.3 24.3 SIN3A "DKFZP434K2235, KIAA0700" ENSG00000169375 "SIN3 transcription regulator family member A" Q96ST3 15 75369379-75455842 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004506, HPA047213, HPA062123" Enhanced Enhanced Nucleoplasm NA NA Nucleoplasm "CAB004506: AB_2187766, HPA047213: AB_2679984, HPA062123: AB_2684689" "unprognostic (1.94e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-1)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (8.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (3.52e-1)" 21.0 15.4 14.0 19.4 18.5 31.6 20.4 26.3 15.5 26.3 20.2 19.9 15.3 11.8 26.6 16.8 17.7 22.1 15.9 13.4 14.2 11.8 13.6 13.9 17.4 20.7 13.0 14.2 27.6 19.8 23.4 16.8 17.2 13.0 22.9 14.3 23.0 17.6 20.5 18.2 23.5 17.9 24.5 12.8 20.3 16.8 28.5 15.1 48.7 24.0 12.8 26.9 26.0 19.0 9.8 6.5 9.3 8.3 9.7 12.7 6.3 12.9 26.9 24.1 15.8 12.0 12.7 13.9 9.7 15.2 14.4 15.5 14.8 17.7 28.3 10.2 14.4 19.7 23.3 34.9 14.7 15.8 22.8 18.1 26.7 20.5 11.6 9.1 25.3 22.9 15.4 11.4 16.7 17.5 14.9 12.9 20.3 21.0 31.6 11.6 15.1 24.8 16.3 23.4 17.3 11.3 25.1 31.9 17.4 10.3 23.9 19.1 19.0 24.1 10.8 13.5 24.2 16.4 20.1 11.2 17.9 24.2 11.8 14.4 21.8 34.0 30.1 10.6 25.9 9.9 3.3 4.8 6.9 8.5 4.8 12.7 9.3 10.8 10.7 6.5 9.8 11.1 9.5 9.3 9.7 8.3 4.4 9.5 6.3 14.0 18.5 26.3 15.5 14.2 11.8 13.0 14.2 13.0 15.1 32.8 26.7 28.9 21.6 34.9 19.3 12.6 17.8 29.4 31.8 26.2 29.5 18.2 5.0 13.3 6.8 23.9 11.8 0.0 11.0 9.1 23.6 23.5 29.9 14.3 11.4 19.1 16.6 26.4 23.0 3.1 21.3 20.0 10.1 12.6 17.1 17.2 12.3 15.0 19.1 8.4 31.7 12.9 17.6 37.7 41.7 46.4 18.3 22.3 15.9 16.6 SIN3B KIAA0700 ENSG00000127511 "SIN3 transcription regulator family member B" O75182 19 16829400-16880353 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Peritubular cells: 62.6;Syncytiotrophoblasts: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050329 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA050329: AB_2681089" "unprognostic (2.71e-3)" "unprognostic (8.89e-2)" "unprognostic (1.32e-3)" "unprognostic (6.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.05e-2)" "unprognostic (5.44e-2)" "unprognostic (9.89e-2)" "unprognostic (5.42e-3)" "unprognostic (2.77e-1)" "prognostic favorable (4.37e-4)" "prognostic unfavorable (3.58e-4)" "unprognostic (1.18e-3)" "unprognostic (8.45e-2)" "unprognostic (1.49e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" 19.1 17.9 22.2 17.2 28.1 9.8 21.5 25.1 38.6 24.4 16.0 20.8 50.0 12.8 37.5 21.5 14.5 23.3 17.3 15.7 24.2 20.8 15.9 9.8 21.7 20.8 16.5 30.4 32.5 16.2 60.8 17.7 53.2 24.8 22.7 11.0 15.5 20.2 54.7 17.1 22.7 17.7 26.5 14.8 25.1 13.7 30.2 13.4 9.3 22.5 9.6 15.8 17.2 22.2 4.8 2.6 6.1 6.7 1.9 2.0 2.3 14.7 7.9 13.4 17.2 11.1 10.2 42.4 12.6 10.4 17.5 15.6 19.4 13.9 13.3 14.1 14.5 14.8 12.7 11.1 11.3 16.2 13.8 20.0 14.2 17.3 8.8 14.6 8.3 11.5 16.8 14.9 11.7 10.1 13.9 15.8 10.7 11.5 8.2 12.2 17.7 11.2 13.4 16.6 7.7 25.4 14.9 12.3 8.7 9.9 12.6 9.9 12.4 15.9 12.3 9.9 18.8 8.6 7.8 20.7 17.0 10.4 24.5 14.0 11.8 8.6 13.3 11.8 10.9 12.6 0.1 6.7 6.1 1.8 6.0 1.2 4.8 1.7 2.0 2.1 3.8 2.0 1.4 3.3 1.9 5.3 2.6 0.5 2.3 22.2 28.1 25.1 38.6 24.2 20.8 16.5 30.4 24.8 13.4 20.8 14.8 10.7 8.6 7.0 18.1 6.9 2.5 5.3 7.9 3.5 13.7 17.1 3.3 9.2 7.9 11.7 4.7 0.0 7.4 24.5 8.6 10.0 4.7 5.6 15.1 9.5 4.7 8.0 13.0 18.2 46.9 6.6 5.0 10.0 7.9 8.7 12.5 3.5 62.6 4.5 15.7 6.5 6.6 9.3 10.4 7.0 104.5 6.4 5.8 11.2 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967201-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Urothelial cells: 181.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" NA NA 17000 "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favorable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 15.2 11.2 13.7 11.0 36.7 14.6 16.1 16.7 13.1 16.6 19.0 9.9 10.9 9.1 17.0 12.1 40.2 12.1 13.6 17.2 10.6 7.1 14.9 12.2 17.1 10.1 11.2 13.4 17.2 12.5 22.6 13.1 17.4 12.8 19.3 13.6 11.4 19.8 12.7 19.3 16.6 15.5 29.8 13.0 12.1 15.7 10.2 12.8 12.0 15.8 21.6 12.5 24.9 23.6 1.4 2.2 6.5 1.4 1.3 3.6 0.7 21.6 12.7 15.1 10.8 16.4 22.9 6.4 13.5 18.0 10.1 9.5 8.0 23.3 11.5 8.5 13.9 8.6 23.6 8.0 17.1 14.8 9.2 11.0 11.7 10.4 6.7 12.3 13.9 10.1 11.7 22.5 13.6 39.9 14.1 18.1 7.5 14.6 8.0 13.2 7.5 9.7 7.7 3.7 14.0 8.1 9.5 18.6 6.0 13.2 25.0 3.5 6.2 11.7 11.4 11.2 8.0 5.9 10.1 27.3 7.4 7.8 13.6 15.8 9.7 11.8 7.3 11.0 18.8 4.7 1.2 1.4 3.3 3.6 1.2 3.6 1.1 2.2 2.2 1.2 1.4 1.5 2.5 6.5 1.3 1.0 2.2 1.4 0.7 13.7 36.7 16.7 13.1 10.6 7.1 11.2 13.4 12.8 12.8 166.7 108.1 23.8 57.3 50.6 27.3 89.7 28.1 66.9 138.8 41.8 23.6 27.8 3.3 28.4 6.3 53.4 45.3 23.3 46.5 11.5 39.3 60.5 32.5 21.7 17.3 23.8 17.7 41.7 24.0 11.0 43.1 31.1 8.5 37.9 31.8 23.4 61.5 54.9 59.4 11.3 24.1 6.5 34.9 42.3 39.1 59.8 43.8 21.8 29.4 181.1 SMARCD3 "BAF60C, CRACD3, Rsc6p" ENSG00000082014 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" Q6STE5 7 151238764-151277896 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.2" "Cell type enhanced" "Detected in many" 7 "Cardiomyocytes: 59.6;Peritubular cells: 83.1;Sertoli cells: 64.7;Smooth muscle cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 3.1;monocytes: 8.8" "Cell line enhanced" "Detected in many" "AN3-CA: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063955, HPA065517" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA063955: AB_2685159, HPA065517: AB_2685500" "unprognostic (1.23e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.38e-3)" "unprognostic (4.67e-1)" "unprognostic (1.41e-3)" "unprognostic (2.24e-2)" "unprognostic (3.52e-2)" "unprognostic (1.63e-1)" "unprognostic (3.50e-1)" "unprognostic (2.08e-3)" "unprognostic (9.18e-2)" "unprognostic (1.02e-1)" "unprognostic (2.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.35e-3)" "unprognostic (1.29e-1)" 9.7 16.0 34.2 4.0 40.3 4.9 9.8 25.4 36.8 12.9 5.6 7.8 7.9 2.9 8.6 11.4 6.7 14.5 10.7 38.5 22.2 24.7 4.9 2.0 8.3 4.0 18.7 18.8 19.2 7.5 6.8 14.7 4.6 13.3 10.8 3.6 7.6 6.6 18.1 75.2 5.7 3.4 10.0 14.1 4.3 4.8 9.0 11.6 0.0 7.4 9.5 2.5 10.1 4.8 0.2 2.6 3.1 8.8 0.0 0.8 2.1 0.3 2.8 9.4 33.3 15.0 6.7 0.7 6.1 6.2 3.6 2.1 2.1 1.9 3.6 2.2 9.6 1.4 0.6 7.5 0.6 1.4 1.1 4.6 0.0 1.9 0.6 12.9 0.1 6.1 15.9 0.8 1.2 0.1 15.7 0.7 9.3 7.2 1.2 19.0 3.8 0.6 4.7 2.9 0.9 1.2 0.2 14.8 0.1 3.2 0.0 5.4 11.0 5.8 1.0 4.4 1.5 0.8 9.3 1.1 2.3 3.7 7.1 2.0 7.9 0.0 3.0 6.6 8.2 10.3 0.6 8.8 0.0 0.2 1.9 0.1 0.2 0.8 0.0 2.6 0.0 0.5 0.8 3.1 0.0 0.4 0.0 0.7 2.1 34.2 40.3 25.4 27.9 22.2 24.7 18.7 18.8 13.3 11.6 6.0 20.8 0.0 31.9 9.5 12.7 59.6 17.8 6.7 5.7 10.4 3.9 0.4 26.6 14.9 1.8 4.7 0.0 0.0 2.1 0.2 19.3 7.3 2.3 0.4 3.4 11.1 3.4 2.5 17.1 8.9 46.9 6.4 6.8 1.0 0.0 23.4 4.3 0.0 83.1 1.7 4.6 64.7 51.5 1.7 9.5 4.1 0.9 0.9 0.0 8.1 SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1, nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804853-18926454 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006870, HPA031623, HPA073972" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA006870: AB_1079725, HPA031623: AB_2673962, HPA073972: AB_2686648" "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (5.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (8.32e-3)" "unprognostic (7.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" 4.7 3.0 2.1 4.5 3.5 11.7 6.2 13.2 3.0 4.4 4.5 3.1 5.4 5.1 5.5 4.0 3.0 4.5 2.3 2.2 4.6 5.4 4.1 6.2 2.3 6.3 4.5 7.2 3.9 3.1 4.2 5.0 4.7 3.3 21.1 14.4 5.0 3.9 3.4 4.5 4.3 4.0 6.0 5.8 5.2 4.9 7.1 4.6 19.1 5.6 2.3 6.1 1.0 23.5 15.8 14.9 10.5 17.1 18.1 11.1 11.0 10.9 12.0 13.5 13.9 8.7 32.5 15.9 15.3 12.7 13.4 17.1 9.6 19.2 20.9 10.7 14.8 13.9 17.7 13.9 19.9 11.7 10.6 16.3 24.9 30.0 11.9 16.8 17.7 22.7 18.1 13.2 12.6 13.7 11.9 15.9 8.6 9.1 15.9 20.1 11.1 10.4 18.5 13.5 10.4 17.1 11.6 12.1 12.8 9.3 12.7 21.2 18.1 12.1 11.1 16.3 9.3 12.0 21.4 12.0 15.5 10.8 19.1 2.5 3.4 6.1 2.8 2.9 3.7 4.0 4.3 2.5 7.1 5.4 4.7 7.6 2.3 5.6 4.6 3.7 1.0 71.5 85.2 53.9 67.9 171.7 51.1 42.5 20.4 48.2 92.1 26.2 70.7 16.8 3.3 19.5 15.5 65.3 48.7 23.3 20.4 15.0 55.9 71.2 38.1 39.9 21.0 39.7 37.7 36.8 38.1 15.4 27.6 61.1 37.1 36.1 38.6 20.1 26.6 57.5 24.8 12.2 43.3 45.3 56.7 45.2 29.8 178.7 25.1 60.7 35.2 83.0 SMURF1 KIAA1625 ENSG00000198742 "SMAD specific E3 ubiquitin protein ligase 1" Q9HCE7 7 99027438-99144100 "Enzymes, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Urothelial cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019671, HPA055245" Approved Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA019671: , HPA055245: AB_2682757" "unprognostic (2.21e-1)" "unprognostic (6.15e-2)" "unprognostic (8.88e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (3.92e-3)" "unprognostic (2.58e-1)" "unprognostic (1.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.81e-1)" "unprognostic (4.62e-2)" 15.0 11.1 8.7 10.5 15.0 23.8 12.4 12.1 16.5 11.8 10.9 20.9 6.9 9.5 11.6 5.7 19.3 10.2 12.5 7.9 9.3 8.4 10.3 10.1 16.0 8.1 15.4 9.4 19.6 22.5 9.0 15.1 15.4 14.9 11.7 10.6 14.3 13.4 9.6 10.7 17.3 10.3 9.8 10.6 9.1 19.5 26.0 11.8 6.6 7.8 6.6 12.7 11.5 13.3 1.2 1.2 2.4 1.9 1.0 2.1 0.6 13.7 7.9 6.4 4.5 5.1 5.4 9.6 7.7 7.4 6.3 5.9 3.9 11.4 4.3 8.4 7.2 13.9 7.5 3.5 10.0 6.5 3.2 3.0 2.3 4.6 3.8 4.8 2.6 5.7 4.8 6.9 9.9 11.5 9.6 5.9 4.2 6.9 7.6 5.8 11.2 4.5 5.4 7.5 7.6 8.5 4.3 6.0 2.6 6.9 11.4 2.8 6.4 7.4 9.8 6.8 11.8 3.1 5.0 8.7 10.0 10.3 17.8 15.4 6.8 4.6 4.5 5.0 5.2 15.4 2.0 1.4 2.3 1.3 1.5 1.6 0.9 2.1 1.3 1.1 1.2 1.2 1.0 2.4 1.0 1.9 1.2 2.0 0.6 8.7 15.0 12.1 16.5 9.3 8.4 15.4 9.4 14.9 11.8 17.9 28.0 5.2 20.4 23.0 25.8 3.9 20.4 20.1 20.5 12.2 7.9 6.1 1.7 13.9 3.7 10.8 7.8 0.0 13.9 8.0 10.1 31.9 2.3 6.7 5.7 25.4 10.9 7.4 3.1 5.3 5.8 8.5 8.5 4.6 8.7 3.7 25.0 10.5 13.1 4.4 6.9 6.5 15.5 41.5 1.0 19.3 17.6 2.5 7.8 65.2 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542295-64662068 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 55.2;HBF TERT88: 42.4;LHCN-M2: 42.4;TIME: 48.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA071508: AB_2686406" "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 12.3 9.2 10.5 9.0 15.0 11.5 10.2 16.7 10.0 9.2 9.1 11.5 8.1 9.3 7.9 6.9 7.6 7.8 10.5 8.2 12.6 4.6 9.4 5.7 19.0 8.6 9.5 4.8 8.5 9.0 8.2 10.7 15.3 10.1 10.6 8.2 9.6 9.9 7.6 7.5 11.0 13.7 8.9 6.6 9.9 9.8 21.6 10.6 8.9 11.4 4.1 9.6 9.4 11.7 3.0 3.0 4.8 2.2 7.3 3.5 1.7 15.9 4.4 3.8 2.8 2.6 10.2 1.8 55.2 25.1 21.6 18.8 2.4 12.2 2.1 3.5 9.4 8.5 3.5 3.6 9.5 42.4 1.1 2.4 2.2 2.7 2.9 2.4 2.9 1.4 2.7 3.7 29.9 11.5 13.1 24.9 2.7 3.3 2.1 42.4 3.5 6.8 1.3 2.2 2.5 5.8 1.6 9.2 1.4 5.9 2.8 3.6 3.2 3.4 1.7 2.5 7.3 2.9 2.4 48.9 24.5 13.3 9.4 36.6 2.4 2.9 3.8 6.0 1.7 7.4 2.8 2.2 4.8 3.3 2.0 2.8 2.0 2.4 3.5 3.0 3.0 2.3 2.6 4.4 7.3 1.0 2.6 1.1 1.7 10.5 15.0 16.7 10.0 12.6 4.6 9.5 4.8 10.1 10.6 29.8 21.3 9.5 27.8 38.9 26.4 9.1 7.6 13.4 19.4 8.7 41.2 10.4 8.3 13.5 18.7 24.0 18.8 0.0 8.4 2.7 21.3 22.7 12.7 4.5 12.6 25.4 17.1 43.6 16.7 7.8 11.5 14.0 20.3 4.6 10.3 20.6 18.4 17.3 11.3 7.4 46.8 0.0 20.3 31.2 24.5 34.8 6.1 20.8 11.5 21.8 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Ito cells: 86.5;Sertoli cells: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 51.9;TIME: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 31.5 8.8 9.8 13.1 14.4 41.0 22.6 34.5 21.1 17.6 14.4 7.9 5.9 12.8 20.9 10.5 16.2 11.5 16.4 13.9 11.0 11.0 16.8 20.3 24.7 19.8 11.4 10.6 15.1 18.0 18.4 16.2 26.2 22.5 12.1 9.9 14.7 10.7 9.4 12.5 24.5 17.0 18.7 9.8 25.4 11.2 13.9 7.2 48.4 24.8 13.5 14.4 15.8 19.3 3.2 3.0 20.9 5.5 8.1 10.7 6.5 3.3 2.0 3.8 3.6 11.3 4.0 3.6 3.6 6.1 3.9 3.8 2.8 4.8 5.3 2.8 4.5 2.6 2.1 4.4 7.7 4.1 6.0 3.6 6.0 3.8 3.2 5.9 6.7 6.7 4.5 5.3 4.4 7.5 4.0 51.9 6.1 2.6 6.1 3.5 1.7 6.8 5.9 4.2 1.8 9.3 4.7 2.8 5.5 10.1 5.7 2.7 5.6 3.1 3.3 4.3 3.4 2.3 8.6 30.2 3.4 3.5 3.9 4.1 9.9 7.1 4.5 2.4 8.1 4.9 4.8 2.8 5.4 7.6 5.5 10.7 2.8 6.7 7.6 3.0 3.2 10.1 10.1 20.9 8.1 5.0 0.9 7.1 6.5 9.8 14.4 34.5 21.1 11.0 11.0 11.4 10.6 22.5 7.2 29.8 30.3 12.9 9.7 46.9 49.8 14.5 22.9 16.0 18.2 15.7 15.7 6.3 10.0 9.2 40.0 52.3 28.4 0.0 7.8 2.7 11.8 9.9 13.9 21.3 11.3 28.6 10.4 86.5 27.6 4.9 11.5 16.6 21.9 4.6 8.9 15.6 8.4 8.2 11.0 10.4 17.2 122.9 26.4 10.7 15.7 44.8 6.9 41.7 8.5 15.4 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023104-45077185 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 66.3;liver: 98.4;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" 17 "Hepatocytes: 654.8;Proximal tubular cells: 226.9" "Cancer enhanced" "Detected in all" "prostate cancer: 72.5" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "eosinophil: 36.4" "Lineage enriched" "Detected in many" 13 "granulocytes: 36.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 430000 Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 1.4 10.2 3.0 1.5 3.2 1.0 7.1 3.1 3.8 66.3 5.5 6.2 39.2 2.6 2.6 3.2 6.7 3.5 3.9 3.4 3.0 3.0 20.9 98.4 1.6 2.2 4.2 2.3 1.6 7.3 1.2 1.8 0.5 5.0 48.5 3.8 2.3 7.6 46.7 1.4 8.0 8.7 2.0 5.0 2.4 5.6 2.5 3.9 3.1 116.3 3.8 3.5 4.2 4.4 1.6 2.4 36.4 2.7 0.4 1.0 1.3 15.6 13.8 3.5 11.3 3.0 5.3 3.7 4.3 3.0 9.9 8.4 11.5 8.6 2.0 9.8 5.3 10.7 23.6 18.1 16.4 7.9 34.0 11.2 15.7 18.1 25.3 2.3 27.3 26.4 6.8 12.5 5.7 9.1 4.8 9.3 24.2 17.6 5.6 9.3 6.3 16.5 14.8 13.5 26.5 14.7 0.0 22.8 7.6 7.2 15.3 24.8 13.0 8.9 14.0 6.6 3.9 20.2 11.2 8.3 7.9 7.0 17.6 10.4 1.0 6.9 2.0 12.8 24.1 20.6 5.0 2.7 36.4 0.6 2.5 1.0 1.2 0.6 0.8 2.4 1.6 0.5 0.6 1.4 0.4 2.5 1.3 0.6 1.3 3.0 3.2 3.1 3.8 3.0 3.0 4.2 2.3 5.0 3.9 0.0 1.9 16.8 20.6 6.9 9.5 2.8 38.2 28.1 28.4 31.4 0.0 1.0 24.9 52.5 26.1 3.8 9.1 0.0 118.4 3.9 5.8 134.4 8.1 654.8 14.4 3.2 81.4 20.9 21.2 17.1 3.4 8.2 15.1 8.2 29.3 6.8 90.9 13.3 5.6 226.9 3.6 0.0 9.2 6.5 2.5 17.8 0.8 6.4 32.6 87.8 SPEG "APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta" ENSG00000072195 "SPEG complex locus" Q15772 2 219434846-219498287 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 88.7" "Cell type enhanced" "Detected in many" 9 "Cardiomyocytes: 55.0;Late spermatids: 30.8;Sertoli cells: 45.3;Smooth muscle cells: 36.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 27.9;U-87 MG: 14.6" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 7.7 7.1 10.1 9.1 7.7 1.2 4.2 10.4 9.8 19.2 45.1 4.1 10.5 5.7 31.6 14.1 13.5 19.0 17.4 17.8 8.7 5.3 2.0 1.4 3.0 1.7 4.0 8.0 7.0 2.9 4.7 10.5 4.8 5.5 16.7 4.5 6.7 7.8 23.0 88.7 2.2 9.2 45.2 9.1 1.9 16.1 3.0 3.9 0.0 2.0 16.8 1.6 22.5 12.6 0.0 0.3 0.0 0.0 0.0 0.5 0.7 3.6 0.3 1.8 3.1 0.9 2.9 1.2 7.7 5.2 5.2 3.9 2.8 1.3 0.0 2.8 5.6 2.9 4.5 1.5 1.8 2.0 0.4 1.2 0.4 3.3 0.1 1.3 0.0 0.6 8.2 2.7 4.7 1.1 27.9 0.0 2.0 2.7 0.0 3.7 1.0 0.0 11.0 3.9 0.1 1.4 1.8 4.2 0.6 5.0 0.0 2.1 9.6 0.5 0.0 0.1 9.2 0.3 0.1 0.1 13.0 13.2 1.5 12.1 0.4 0.0 0.1 14.6 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.7 10.1 7.7 10.4 9.8 8.7 5.3 4.0 8.0 5.5 3.9 0.0 2.1 0.0 5.6 2.9 1.1 55.0 5.1 0.0 0.0 1.8 2.0 0.8 0.0 1.2 17.7 1.4 5.9 0.0 1.0 0.7 8.5 2.7 0.0 2.4 1.0 4.8 6.4 3.7 6.6 30.8 9.8 1.7 3.3 1.8 3.3 6.5 0.3 2.9 17.7 2.3 0.8 45.3 36.2 1.1 2.6 1.3 1.1 0.0 2.4 3.5 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 8 "Early spermatids: 311.7;Late spermatids: 401.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 13.5 7.1 8.1 15.4 11.7 32.1 11.7 22.5 17.8 12.8 23.8 7.8 10.8 20.3 15.2 7.9 24.9 8.9 10.8 8.7 8.9 7.8 17.8 18.9 14.9 14.6 8.0 8.3 9.5 26.0 11.7 17.7 27.9 9.6 10.5 28.7 12.4 17.6 9.4 19.9 26.2 25.7 11.3 7.9 19.0 13.9 32.7 7.6 21.0 8.5 17.0 19.8 15.2 15.7 4.3 2.8 24.6 3.4 5.0 6.7 2.9 29.9 11.4 16.8 25.0 9.4 12.3 21.2 18.4 17.8 17.2 18.3 32.0 10.1 40.0 15.6 11.3 20.0 15.4 32.8 21.9 31.0 27.3 23.6 21.0 13.4 27.7 8.3 31.1 10.4 7.9 12.0 19.8 26.0 13.7 21.6 22.9 44.5 17.0 14.4 10.6 32.0 24.2 13.7 18.3 12.5 22.5 20.1 24.7 17.3 50.4 35.8 13.1 18.9 18.0 12.7 17.8 10.1 20.7 15.6 16.2 12.7 11.0 23.1 10.0 22.1 37.6 6.4 36.1 14.4 24.5 2.1 13.7 4.3 2.5 6.1 4.3 5.7 5.7 2.8 3.3 4.8 5.2 24.6 5.0 3.4 1.6 6.7 2.9 8.1 11.7 22.5 17.8 8.9 7.8 8.0 8.3 9.6 7.6 8.9 26.3 24.4 65.1 37.5 33.6 21.8 12.7 32.1 38.7 21.0 35.3 43.2 24.9 50.7 311.7 24.1 38.6 23.3 58.8 43.3 21.3 68.6 7.0 40.0 19.1 9.5 44.4 11.1 17.1 401.7 20.4 16.9 15.1 36.1 44.8 13.4 78.7 42.1 23.3 44.4 84.4 6.5 23.1 154.9 90.6 36.5 33.2 34.8 87.4 132.9 SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.3" "Group enriched" "Detected in many" 6 "Early spermatids: 1076.1;Late spermatids: 1865.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 58.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015522, HPA020876" Enhanced Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA015522: AB_1857479, HPA020876: AB_1857480" "unprognostic (9.75e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (4.64e-2)" "unprognostic (3.54e-1)" "unprognostic (1.30e-1)" "unprognostic (5.14e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (7.95e-2)" "unprognostic (4.72e-2)" "unprognostic (2.87e-2)" "unprognostic (3.44e-1)" 9.9 12.1 24.8 10.1 27.6 7.1 13.3 28.4 47.1 12.7 9.4 21.0 7.8 8.2 13.2 11.9 11.9 10.9 11.6 10.4 26.4 28.6 10.3 10.1 9.2 11.5 27.2 30.2 13.0 10.5 11.9 15.3 12.0 27.3 14.0 10.9 7.9 10.1 11.1 7.9 16.9 8.2 13.3 23.1 12.0 11.3 69.3 32.3 22.1 11.3 4.7 14.0 13.6 9.7 12.2 7.3 58.2 8.1 10.0 11.9 6.0 13.3 8.9 14.2 28.1 15.2 17.2 7.9 13.1 15.3 13.1 15.3 6.9 11.4 8.5 16.7 16.9 14.7 8.0 14.3 13.8 16.8 14.7 12.7 12.0 8.4 6.0 17.6 11.4 18.0 11.9 25.7 11.1 20.9 12.7 22.5 20.3 11.8 34.8 14.5 25.2 42.2 8.7 11.7 7.6 9.7 13.7 15.6 18.4 18.9 20.7 20.8 14.4 14.8 22.3 13.8 19.6 8.3 8.0 14.7 24.2 17.6 23.0 12.2 38.2 37.6 20.9 9.5 11.8 18.0 11.2 8.1 26.0 11.9 5.5 7.1 12.2 9.0 8.9 7.3 11.6 8.5 9.7 58.2 10.0 6.2 6.4 10.1 6.0 24.8 27.6 28.4 38.7 26.4 28.6 27.2 30.2 27.3 32.3 26.8 28.5 33.3 51.2 189.1 70.3 20.1 33.1 48.2 27.3 22.7 47.1 40.1 23.2 44.1 1076.1 52.5 12.9 0.0 40.5 30.6 44.1 65.7 40.4 25.1 41.0 117.6 27.6 43.0 45.7 1865.0 71.1 31.8 55.6 40.5 32.1 65.3 32.7 21.0 90.2 21.7 65.2 45.3 45.3 237.2 50.3 90.3 53.9 56.8 23.6 46.7 SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 73.4" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 23.8;Cone photoreceptor cells: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RH-30: 31.4;U-266/70: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" 1.6 1.8 1.3 0.9 1.8 0.8 0.3 7.7 1.5 0.9 4.5 1.1 0.2 1.3 2.5 3.3 2.6 0.7 1.7 16.7 2.0 1.8 0.2 0.2 0.4 0.8 2.0 0.7 0.7 0.7 1.0 5.8 0.3 1.1 2.8 0.8 0.9 2.9 0.5 73.4 2.3 1.3 4.0 2.0 0.8 1.3 0.5 0.9 0.3 0.6 18.3 1.6 2.0 0.8 0.4 2.6 0.9 0.3 0.1 0.6 0.3 3.2 4.4 0.8 2.2 0.0 0.1 1.0 0.4 0.0 0.2 0.0 3.7 0.6 3.3 0.4 0.4 0.3 0.9 0.0 0.1 0.0 2.8 3.1 1.7 2.7 0.6 0.0 0.8 5.1 2.8 0.0 0.0 0.0 0.2 0.0 4.7 2.2 3.9 0.9 7.0 0.6 4.8 0.8 0.2 1.2 1.5 31.4 0.9 0.0 1.5 5.3 2.5 0.0 2.3 1.0 0.3 2.9 3.8 0.1 1.2 2.8 2.3 0.4 13.0 2.1 2.2 0.6 6.2 1.6 0.8 0.3 0.2 0.5 0.1 0.6 0.2 0.1 0.1 0.0 0.4 0.1 0.1 0.9 0.1 0.0 2.6 0.0 0.3 1.3 1.8 7.7 1.5 2.0 1.8 2.0 0.7 1.1 0.9 0.0 0.0 0.0 1.0 0.6 2.2 23.8 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.7 0.0 0.0 2.8 0.0 0.2 0.0 2.7 0.0 0.1 0.4 0.0 0.0 0.2 0.3 SSH1 KIAA1298 ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778192-108857590 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 7.3 7.8 8.5 7.4 8.1 10.6 9.3 20.3 8.8 7.4 8.5 6.8 13.1 4.4 9.8 7.9 7.6 8.2 8.3 10.1 8.0 6.9 5.8 7.4 10.1 8.7 7.7 5.2 7.9 8.0 9.7 6.8 7.8 8.4 6.5 6.5 15.0 5.9 8.0 21.4 7.1 6.5 10.4 8.1 8.6 7.1 5.2 6.6 2.0 7.0 7.9 6.6 10.0 13.3 1.8 2.0 5.7 4.0 2.1 2.9 1.2 5.1 6.8 4.5 3.5 8.5 7.3 4.0 6.6 14.2 6.1 5.4 3.4 2.5 2.4 4.7 15.5 10.4 5.1 2.7 11.2 5.0 5.0 2.6 5.7 3.1 2.1 4.6 2.9 15.2 10.0 3.8 5.5 12.3 15.1 5.6 3.0 1.3 2.0 15.9 2.9 3.3 4.2 3.1 2.0 5.5 2.4 5.3 3.2 2.4 9.2 3.3 4.5 5.8 1.6 12.8 6.5 2.1 2.6 4.4 10.9 4.7 6.5 3.8 3.9 3.5 3.0 5.7 2.4 34.4 4.2 2.4 4.8 2.9 4.0 2.7 1.6 1.5 2.5 1.6 1.8 1.4 1.6 5.7 2.1 3.2 2.0 1.7 1.2 8.5 8.1 20.3 8.8 8.0 6.9 7.7 5.2 8.4 6.6 8.9 17.3 4.7 15.4 8.4 10.6 21.2 12.7 8.1 14.8 14.0 15.7 4.7 5.0 7.7 1.6 37.5 3.5 0.0 7.0 3.7 10.3 7.2 19.7 13.4 11.2 11.1 5.2 25.8 24.7 2.6 6.1 17.8 11.8 43.3 6.6 8.8 10.1 0.0 12.0 4.9 20.7 6.5 17.6 1.1 6.6 7.9 1.9 15.4 5.7 12.2 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" 4 "Kupffer cells: 119.4;Late spermatids: 117.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain NA NA "CAB017189: , HPA057099: AB_2683336" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 12.3 7.7 15.8 19.0 16.0 43.1 7.9 23.9 18.0 6.8 10.6 17.5 8.8 7.4 6.1 8.5 9.4 6.5 7.9 12.0 12.9 8.4 10.8 9.8 15.1 20.9 13.6 12.4 3.7 11.8 6.4 6.5 8.8 10.6 5.1 10.0 7.9 8.6 11.6 59.6 10.5 14.5 6.9 12.6 21.3 10.3 26.1 15.2 22.7 10.7 9.5 19.9 7.8 6.5 7.9 4.0 37.8 4.5 1.4 5.9 1.8 12.0 9.8 6.3 5.4 17.4 11.9 3.7 6.0 6.8 9.9 10.5 5.3 4.5 10.0 9.6 7.1 6.6 14.0 7.7 8.7 11.5 3.5 13.7 6.9 10.0 7.7 8.2 7.4 15.0 14.0 5.8 10.5 7.0 4.9 22.6 17.8 4.9 7.8 6.9 3.4 34.8 7.5 4.7 4.6 5.1 16.7 15.9 17.5 17.1 9.4 10.6 11.8 8.7 9.7 17.3 8.9 6.4 7.8 12.4 6.7 13.8 11.8 7.2 11.9 7.8 25.0 8.0 5.9 6.2 11.0 3.8 37.8 3.5 4.5 2.9 7.5 4.4 3.5 4.0 7.9 4.1 3.0 9.6 1.4 3.8 2.6 5.9 1.8 15.8 16.0 23.9 18.0 12.9 8.4 13.6 12.4 10.6 15.2 8.9 36.3 54.0 11.9 35.1 12.4 22.6 10.2 12.0 13.6 15.7 25.5 18.7 21.6 14.9 77.6 21.9 36.6 0.0 30.8 18.1 14.6 14.0 11.6 24.1 20.1 19.1 34.0 22.1 119.4 117.3 11.2 43.4 33.7 19.0 31.7 6.8 31.7 27.4 7.8 39.3 20.1 6.5 14.4 41.9 16.4 31.7 15.2 40.3 22.3 20.4 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303448-67312607 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 10.8;eosinophil: 10.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.8" "Cell line enhanced" "Detected in many" "HaCaT: 23.8;RT4: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 8.6 5.5 5.6 6.8 9.7 8.1 13.5 17.8 9.4 14.6 15.9 15.4 19.5 12.4 10.1 10.6 27.0 15.2 20.5 7.7 6.0 6.1 10.3 7.5 9.0 3.5 13.6 5.4 17.1 12.0 11.3 7.4 20.0 8.5 19.8 9.2 11.9 19.1 30.5 5.2 18.2 13.6 13.1 9.3 6.9 13.9 4.2 9.7 0.8 12.8 14.0 13.2 33.3 18.6 0.3 1.6 10.8 2.3 1.5 2.2 1.0 6.2 6.7 0.1 0.2 4.8 4.9 7.4 4.1 5.4 2.1 2.0 7.3 16.5 0.3 12.6 3.7 4.5 23.8 2.2 17.2 1.2 1.3 2.5 1.6 10.9 2.9 3.3 0.3 6.1 4.3 15.9 3.1 3.3 5.0 2.4 0.1 0.0 0.6 2.5 21.0 0.2 3.0 1.5 17.0 5.4 7.7 0.2 1.1 7.0 36.0 1.4 2.2 9.5 14.1 4.4 2.6 19.8 5.2 3.9 1.7 3.7 4.8 1.1 0.7 0.3 0.2 4.9 2.7 1.6 10.8 1.4 10.5 2.2 2.3 1.7 0.3 2.1 1.8 1.6 0.2 0.8 0.9 4.5 1.5 1.1 1.1 1.8 1.0 5.6 9.7 17.8 9.4 6.0 6.1 13.6 5.4 8.5 9.7 3.0 5.4 0.0 20.7 6.3 1.1 3.4 15.3 8.1 10.3 15.7 0.0 12.6 3.3 16.4 0.0 3.9 17.2 0.0 19.0 20.2 6.2 13.1 3.5 4.3 6.8 1.6 3.5 4.3 8.6 0.0 12.0 2.9 8.5 12.6 14.7 4.6 16.4 17.5 11.3 6.3 0.4 0.0 8.3 0.3 0.0 9.2 13.2 4.3 18.5 22.9 SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574869 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 520.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol No No "Nucleoplasm, Cytosol" "HPA069290: AB_2686108, HPA070604: AB_2686285" "unprognostic (3.33e-2)" "unprognostic (2.79e-2)" "unprognostic (6.37e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "unprognostic (9.84e-2)" "unprognostic (2.40e-3)" "unprognostic (2.43e-2)" "unprognostic (3.23e-1)" "unprognostic (3.23e-1)" "unprognostic (6.75e-2)" "unprognostic (1.36e-1)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.77e-1)" "unprognostic (1.06e-1)" 44.1 32.5 48.0 33.6 51.5 29.3 73.9 42.3 51.5 37.2 40.1 25.4 39.3 41.3 32.6 51.8 45.7 46.2 35.3 44.4 40.7 42.5 38.0 50.9 37.5 49.0 39.4 39.0 38.0 61.8 33.9 39.9 35.8 36.9 33.9 35.9 34.1 54.2 35.8 107.1 36.9 40.8 35.4 35.0 41.7 38.5 28.0 28.4 37.0 50.9 45.3 36.3 30.8 42.2 35.5 30.1 62.0 28.8 20.7 46.5 28.1 41.4 26.6 19.2 29.6 33.1 32.0 19.7 36.1 28.2 31.5 32.9 24.9 48.2 42.2 19.8 28.4 30.8 32.4 31.0 29.7 30.8 35.1 36.6 26.5 23.3 39.3 37.5 33.5 23.2 28.5 25.1 33.7 32.2 26.5 29.4 25.7 45.8 32.7 24.9 36.9 38.3 53.8 33.6 40.9 40.4 30.5 31.0 59.0 34.5 12.8 35.6 24.4 24.4 62.7 106.5 34.0 32.7 29.2 22.4 30.4 19.3 34.2 30.9 39.9 47.9 52.7 31.8 53.4 14.7 37.1 28.3 53.6 25.9 28.8 31.9 35.5 34.4 30.7 30.1 33.1 42.2 34.1 62.0 20.7 25.4 19.0 46.5 28.1 48.0 51.5 42.3 51.5 40.7 42.5 39.4 39.0 36.9 28.4 26.8 71.4 136.9 121.9 165.4 98.0 80.5 117.2 36.1 37.5 96.0 19.6 178.0 247.1 62.6 202.0 95.1 177.2 0.0 92.6 189.0 93.0 151.4 60.0 123.8 125.1 106.5 136.4 90.9 152.3 520.2 97.0 118.3 158.6 91.0 137.9 96.8 78.9 168.6 80.6 258.7 57.5 58.2 97.3 81.2 147.4 192.6 205.2 116.7 134.0 129.8 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 162.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 11000 Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: AB_2732470" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 12.9 12.8 22.1 13.9 23.0 10.5 17.8 20.1 21.8 18.1 18.4 35.0 13.6 17.8 23.1 15.4 22.7 16.5 14.7 19.0 23.3 21.2 19.6 16.9 13.4 15.3 33.0 14.3 16.3 15.1 20.9 17.8 20.6 26.3 20.2 20.7 14.6 18.3 15.7 30.1 14.4 25.2 19.0 54.7 13.8 15.6 13.3 22.3 18.4 20.1 15.9 19.0 16.8 16.4 17.6 16.9 27.8 17.8 16.7 20.7 12.3 5.4 6.3 5.0 4.6 4.7 5.7 5.8 3.3 4.6 6.2 6.0 10.5 5.2 4.6 5.3 2.8 8.3 4.3 5.3 11.8 7.1 8.0 6.0 6.1 4.4 8.2 6.5 5.0 7.4 4.5 8.5 7.3 10.6 7.9 3.6 6.3 6.6 7.0 162.7 6.6 7.7 4.5 8.0 7.8 3.4 5.4 13.2 6.5 6.6 6.2 9.2 6.8 4.1 5.0 7.1 5.6 4.7 3.0 3.1 5.6 6.7 3.3 5.9 6.6 6.4 3.5 6.9 5.4 6.5 22.6 16.2 27.8 14.4 17.8 15.4 17.6 16.7 14.0 16.9 16.2 17.5 13.2 24.1 16.7 15.7 16.4 20.7 12.3 22.1 23.0 20.1 21.2 23.3 21.2 33.0 14.3 26.3 22.3 17.9 15.3 14.1 25.1 14.4 19.9 35.5 35.7 25.4 27.3 24.4 11.8 35.2 41.4 32.4 59.2 21.7 40.9 46.7 31.9 28.3 22.6 34.8 51.9 34.7 29.0 25.4 9.9 20.3 24.7 104.7 30.2 29.2 6.8 36.9 31.9 21.5 36.9 38.6 32.5 47.1 19.2 38.8 20.6 32.3 49.5 18.9 37.2 19.5 31.2 23.0 STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 18.6" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 37.8;Spermatocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040202 Uncertain Approved "Plasma membrane" NA NA "Plasma membrane" "HPA040202: AB_10805708" "unprognostic (2.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-2)" "unprognostic (4.67e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (4.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (4.40e-3)" 3.9 15.9 3.7 6.8 5.1 2.8 2.1 12.4 8.9 2.0 5.8 3.4 1.5 4.5 2.7 1.5 2.7 1.2 2.9 4.8 3.3 3.4 1.5 1.7 2.9 11.3 2.6 14.8 8.5 1.8 2.2 6.6 1.5 4.1 1.9 8.0 1.5 1.5 1.5 1.5 3.4 6.1 1.8 3.1 6.0 3.1 18.6 3.2 1.5 1.5 1.5 9.5 3.9 2.7 10.5 15.2 4.3 0.6 13.1 14.7 4.5 6.8 8.1 0.5 0.3 8.1 15.6 0.0 14.4 14.2 9.3 8.3 0.3 13.1 8.4 1.0 7.8 6.2 3.4 2.0 2.9 9.4 7.4 5.1 2.1 5.8 0.4 5.5 9.2 3.0 5.5 0.7 15.5 4.9 10.6 0.2 10.1 0.0 3.8 24.9 1.4 15.3 10.9 3.0 6.5 6.3 1.5 6.1 1.8 3.5 2.6 4.7 5.6 1.8 0.6 16.4 2.0 1.0 1.9 2.1 8.3 6.0 9.9 9.0 8.9 8.4 7.8 9.1 9.4 7.8 4.3 0.6 4.2 6.3 0.6 8.2 10.5 9.2 7.9 0.9 7.0 9.9 5.9 0.9 13.1 0.3 15.2 14.7 4.5 3.7 5.1 12.4 8.9 3.3 3.4 2.6 14.8 4.1 3.2 0.0 5.0 9.3 4.1 8.5 3.7 5.0 0.0 8.1 0.0 5.2 0.0 0.1 0.0 0.8 37.8 2.2 7.4 0.0 1.6 0.1 5.1 1.5 4.7 1.9 3.0 6.4 8.7 1.8 1.0 13.9 6.6 3.5 0.0 1.0 8.1 10.6 1.2 0.0 1.4 0.5 0.2 0.0 6.7 27.6 2.4 9.9 0.1 14.9 13.3 1.6 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042073-172188386 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" 7 "Kupffer cells: 78.5;T-cells: 70.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 27.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 24000 "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 15.0 4.7 2.6 25.8 4.4 38.3 13.5 27.5 3.0 3.6 5.0 4.8 3.4 4.7 4.4 4.4 3.6 4.2 11.0 9.0 2.4 2.5 5.3 4.5 15.4 40.9 5.4 1.9 3.5 4.1 2.5 3.7 16.2 4.5 4.3 4.0 5.6 7.8 2.5 3.1 9.0 12.2 5.7 4.6 33.0 6.2 13.1 3.5 20.6 4.6 3.1 23.7 9.5 11.3 5.0 10.3 22.3 30.8 7.4 18.0 15.6 7.8 7.3 4.5 6.8 5.3 6.6 11.6 10.2 8.5 7.4 6.9 3.8 10.4 9.5 5.4 12.6 15.7 9.2 2.0 12.5 4.8 12.3 3.4 11.4 3.0 2.1 7.6 11.5 13.5 6.5 2.7 10.1 8.4 2.7 6.4 3.7 1.0 13.3 5.2 12.6 8.2 25.8 1.8 3.9 5.8 13.6 3.6 6.2 3.0 9.9 3.1 3.8 5.9 8.3 28.0 5.9 2.9 24.4 8.9 8.3 4.2 5.8 5.5 11.2 16.5 6.0 10.9 17.7 52.3 7.1 10.8 10.0 18.0 21.4 13.3 5.0 9.4 12.8 10.3 4.4 5.6 9.6 22.3 7.4 30.8 3.2 12.2 15.6 2.6 4.4 27.5 3.0 2.4 2.5 5.4 1.9 4.5 3.5 3.0 12.8 25.0 7.9 6.0 3.8 3.6 2.5 5.3 5.7 1.8 5.9 2.8 1.7 4.4 1.7 17.8 8.4 0.0 5.3 25.1 7.4 6.7 26.7 2.1 30.8 44.5 11.5 20.3 78.5 2.7 2.6 39.2 8.5 9.0 15.0 3.1 7.9 7.0 1.4 1.5 2.2 12.9 8.2 5.7 6.8 3.6 4.2 70.5 4.7 9.5 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 124.0;Late spermatids: 234.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.2 10.3 7.8 14.8 7.4 6.7 16.5 10.4 10.9 9.8 10.4 8.4 14.9 13.9 11.5 10.8 4.4 13.8 7.7 16.0 3.0 26.0 18.8 14.2 0.6 10.5 16.0 14.3 23.9 12.2 11.7 7.5 11.2 8.9 9.8 11.1 26.6 19.2 5.5 15.9 13.7 14.5 15.0 7.3 12.7 21.8 8.4 15.6 8.8 15.6 18.1 13.1 0.0 7.7 11.2 4.7 12.1 23.5 13.2 10.1 11.5 19.8 16.5 37.8 15.9 10.4 10.1 19.1 10.4 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 6.0 13.6 11.1 6.4 14.8 23.6 11.8 17.8 2.7 6.8 22.7 17.7 6.7 6.6 8.1 124.0 14.7 29.5 0.0 11.9 4.5 10.4 14.2 2.3 25.2 12.9 17.5 14.5 16.0 22.2 234.7 22.7 10.4 15.1 17.2 29.2 19.3 13.0 25.9 19.4 8.6 19.8 12.9 20.8 49.9 19.4 13.6 7.3 8.6 33.0 10.9 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 10.2 19.0 15.7 12.8 20.3 13.3 14.6 8.8 21.0 11.5 16.2 15.2 20.5 17.2 11.4 22.1 16.0 18.3 15.5 13.0 14.5 11.9 19.5 30.1 11.4 24.6 14.2 13.2 13.2 24.5 16.5 15.1 14.0 13.3 14.3 13.7 12.8 19.0 16.3 9.9 12.2 14.2 11.5 12.3 15.9 16.8 18.9 12.7 27.2 19.8 12.8 17.0 12.9 10.3 7.9 7.8 5.8 7.6 14.5 11.2 9.7 7.4 9.8 8.6 7.3 21.5 21.0 9.9 9.6 13.3 8.2 8.2 11.4 16.6 4.3 13.5 16.0 13.1 7.7 10.0 16.0 4.4 10.5 11.5 9.7 8.9 9.8 19.5 9.2 11.4 22.4 25.7 11.3 29.9 16.2 9.9 10.1 12.1 11.8 14.0 13.7 10.0 20.1 8.0 13.5 6.0 9.5 9.7 12.6 17.1 8.6 6.9 8.8 3.4 13.7 19.7 6.5 14.3 19.5 7.6 11.2 7.9 9.1 9.2 14.6 6.2 10.3 12.4 9.8 9.8 2.0 7.6 5.8 6.0 4.2 6.8 7.8 7.5 11.2 7.8 7.9 7.8 10.0 5.2 14.5 3.6 6.7 8.4 9.7 15.7 20.3 8.8 21.0 14.5 11.9 14.2 13.2 13.3 12.7 6.0 6.4 22.9 15.0 8.8 7.4 7.8 28.1 5.3 5.7 7.0 15.7 20.2 58.0 33.5 69.7 11.7 27.6 0.0 51.6 21.3 17.4 15.1 8.1 39.4 25.1 12.7 24.8 11.6 19.1 56.4 14.1 15.7 20.3 43.3 36.3 18.3 30.3 42.9 12.7 72.1 18.4 0.0 12.2 38.1 6.9 9.8 10.8 30.5 35.9 14.0 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43626786 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.3" "Cell type enhanced" "Detected in many" 10 "Basal glandular cells: 549.3;Urothelial cells: 279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 7.1 10.1 6.1 43.3 8.2 20.2 8.4 7.9 7.2 4.8 9.3 3.7 2.0 6.1 5.3 4.2 10.1 4.7 8.6 17.7 5.7 5.6 6.7 8.1 15.2 36.6 6.6 2.6 7.3 14.3 1.5 6.3 37.2 5.7 6.2 5.3 3.6 8.6 3.4 10.7 4.8 12.3 5.8 5.3 27.8 11.0 9.0 2.8 30.1 7.3 6.8 37.7 10.3 8.1 10.8 1.4 11.5 0.9 12.7 11.4 2.9 4.4 5.5 5.0 3.4 6.3 8.3 2.1 15.9 17.3 8.7 8.9 4.8 3.2 7.1 25.1 13.3 17.8 9.1 3.8 21.2 12.2 17.5 4.3 6.3 4.1 5.9 4.7 10.8 4.2 6.8 25.0 11.5 10.6 34.5 16.3 7.7 7.4 24.4 10.0 2.0 17.6 5.0 7.7 2.6 18.1 6.1 3.2 14.0 15.2 3.3 2.7 6.1 7.2 3.3 4.6 10.7 3.8 5.5 16.3 19.0 7.2 11.2 17.8 14.8 7.3 10.2 19.3 9.6 30.2 0.7 0.4 11.5 5.8 0.2 5.8 10.8 6.1 9.7 0.3 10.1 11.4 10.2 6.4 12.7 0.9 1.4 3.2 2.9 6.1 8.2 7.9 5.9 5.7 5.6 6.6 2.6 5.7 2.8 113.2 27.8 121.1 549.3 161.6 3.0 25.4 5.1 52.2 81.9 19.2 9.8 44.4 28.2 110.3 36.3 19.4 29.1 0.0 82.8 19.7 31.9 134.1 39.1 7.7 15.8 0.0 6.9 16.5 16.2 8.8 5.5 19.9 33.7 55.1 27.8 8.1 75.9 56.1 2.5 9.7 25.2 6.5 55.6 45.1 29.6 118.9 55.8 186.8 10.0 279.4 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133566-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;bone marrow: 103.4;lymphoid tissue: 72.2" "Cell type enhanced" "Detected in many" 5 "B-cells: 158.6;granulocytes: 189.5;Kupffer cells: 142.8;Macrophages: 145.8;T-cells: 178.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 36.3;HMC-1: 36.8;Karpas-707: 34.1;U-698: 39.5" "Region enriched" "Detected in many" 6 "cerebellum: 71.1" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 21.0 4.1 3.2 42.8 3.8 103.4 10.1 3.2 3.3 8.2 18.8 1.1 3.8 8.5 3.4 3.9 8.9 6.3 8.6 5.7 3.3 2.2 7.2 2.9 26.2 53.7 2.3 1.8 3.1 5.0 0.7 3.8 6.5 1.7 6.8 5.7 3.5 16.7 6.1 3.4 10.9 31.8 5.3 2.7 59.3 6.0 4.6 1.4 72.2 7.5 7.0 56.2 11.3 6.0 16.9 13.6 62.0 27.0 10.3 28.4 19.0 3.2 2.2 3.4 1.2 15.0 5.7 3.8 7.7 11.6 8.5 8.9 6.8 1.1 36.3 7.1 4.4 2.2 2.2 1.4 3.3 10.4 6.4 3.8 3.4 2.9 0.6 4.5 13.7 36.8 7.2 3.3 10.5 5.5 12.1 3.5 8.6 2.6 34.1 21.1 1.7 17.8 31.0 1.9 5.9 5.2 2.9 20.7 11.0 5.0 7.6 1.3 1.3 1.9 1.9 1.6 5.5 1.3 7.2 4.2 8.3 4.1 5.9 4.3 14.0 22.6 39.5 6.2 4.7 3.6 35.9 19.7 40.2 12.0 20.7 15.3 13.3 21.5 14.5 13.6 16.9 28.4 23.1 62.0 10.3 27.0 9.7 18.5 19.0 3.2 3.8 3.2 3.3 3.3 2.2 2.3 1.8 1.7 1.4 83.4 80.3 158.6 22.9 53.1 0.3 2.2 10.2 34.8 52.4 10.4 0.0 5.9 3.3 5.2 4.6 11.6 59.1 46.7 2.5 20.9 21.2 28.7 189.5 2.4 23.5 0.0 2.9 7.4 142.8 2.0 5.2 145.8 55.6 40.5 11.0 0.9 7.9 38.6 4.2 1.4 0.2 6.5 20.5 28.6 24.9 55.5 4.2 178.5 10.5 39.9 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 4.9;HEL: 3.6;HL-60: 3.8;REH: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031510, HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA031510: AB_10603119, HPA031511: AB_2673915, HPA068559: AB_2686004" "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 6.4 8.2 3.8 4.3 6.5 2.9 4.0 9.9 6.3 5.7 6.6 5.5 4.2 2.2 6.0 5.5 5.3 3.5 5.3 3.6 5.0 3.5 3.9 6.6 4.1 2.5 4.3 7.5 5.7 12.4 4.7 4.6 6.3 4.0 6.2 2.7 5.6 2.9 6.7 6.1 6.8 2.6 5.9 3.7 7.0 6.3 7.9 4.2 2.6 4.7 4.1 3.8 4.4 4.2 2.1 2.7 0.4 3.8 0.9 1.1 0.5 0.0 0.3 0.0 1.1 3.0 1.7 0.0 2.4 0.3 0.5 1.1 0.0 2.0 1.5 0.6 1.2 0.0 2.1 0.0 0.6 0.9 4.9 0.9 3.6 1.0 0.2 1.5 3.8 0.0 1.6 0.1 0.9 0.3 1.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.6 0.1 0.0 4.5 2.5 1.2 0.0 0.0 1.0 0.9 0.3 0.6 0.2 0.0 1.7 0.0 0.0 0.0 1.1 1.1 0.0 0.1 2.3 0.1 1.9 0.6 0.1 0.0 3.8 0.1 0.6 1.4 0.7 2.1 0.9 0.1 2.7 1.0 1.1 0.5 0.4 0.9 1.4 1.5 0.1 0.5 3.8 6.5 9.9 6.3 5.0 3.5 4.3 7.5 4.0 4.2 8.9 19.2 8.6 14.6 11.6 11.5 7.5 10.2 33.5 22.7 21.0 19.6 30.1 33.2 22.2 63.7 15.8 13.1 0.0 24.4 16.5 21.1 11.5 9.2 19.6 16.6 9.5 18.6 13.5 11.9 51.4 18.7 8.9 16.9 8.2 15.4 23.5 20.7 14.4 17.3 132.6 19.7 32.3 16.9 29.9 17.8 15.8 41.5 21.8 11.2 9.8 STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol No No 2800000 "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavorable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favorable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" 28.6 14.2 15.0 29.7 16.9 19.1 34.8 12.2 21.0 36.3 37.4 12.1 23.0 31.9 24.6 26.5 68.4 20.4 41.3 30.0 14.7 12.8 30.5 14.2 23.9 31.2 10.6 10.1 20.0 20.6 12.4 13.9 38.4 14.7 28.3 28.8 36.8 30.8 21.6 18.8 60.6 67.9 34.8 9.2 31.7 30.2 22.1 7.6 38.2 28.2 41.6 48.5 39.2 45.4 8.1 11.2 11.4 13.4 1.5 13.7 6.7 36.0 11.3 20.0 18.5 30.8 18.5 28.5 16.9 23.8 23.7 23.2 33.0 49.1 25.7 8.6 21.1 14.9 32.7 18.5 37.3 22.7 64.1 9.5 27.5 14.4 18.9 43.6 27.6 19.5 11.9 59.6 18.6 54.9 25.1 20.4 20.3 9.9 17.8 15.5 15.7 20.6 11.4 17.9 49.1 8.5 26.1 12.3 13.9 22.9 32.6 11.7 16.8 10.7 17.3 22.8 31.9 20.8 26.9 27.4 15.1 11.0 12.3 19.4 17.4 9.1 9.6 23.5 16.7 24.8 5.8 13.4 6.1 6.1 10.6 7.2 6.6 11.4 8.7 11.2 8.1 7.8 6.1 11.4 1.5 12.7 7.5 13.7 6.7 15.0 16.9 12.2 21.0 14.7 12.8 10.6 10.1 14.7 7.6 11.9 24.3 29.0 62.3 63.0 20.3 2.8 68.8 34.8 44.3 64.6 53.0 35.6 21.6 29.9 2.5 26.3 110.9 0.0 47.8 36.3 36.7 53.4 18.4 22.9 24.7 9.5 40.9 27.0 68.7 3.4 24.7 40.1 54.0 16.2 70.9 22.1 67.8 59.4 28.7 31.9 11.4 38.8 29.0 1.8 3.6 71.8 16.7 21.8 51.8 117.9 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492674-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 164.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain NA NA "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 17.8 13.6 22.3 14.2 26.0 16.3 12.9 22.3 35.3 16.4 17.1 17.0 13.0 14.6 17.7 15.9 19.3 15.4 16.7 19.0 19.4 20.0 17.3 13.5 13.4 13.5 16.3 20.4 17.5 19.2 18.9 17.1 15.6 16.4 15.1 12.9 13.5 14.2 17.6 164.2 15.3 14.2 17.3 12.6 15.8 16.1 16.8 14.4 15.2 20.0 24.6 12.6 14.6 16.6 15.0 13.6 13.7 16.4 21.5 19.9 10.6 18.7 11.9 23.9 29.6 29.4 20.6 36.7 31.3 21.1 23.9 27.4 13.3 16.6 7.1 8.8 41.7 21.7 16.0 33.6 34.1 29.1 26.7 35.3 20.0 25.3 34.3 26.7 12.1 15.5 29.5 24.5 23.1 18.6 29.4 53.9 26.4 30.8 6.4 43.7 19.7 18.0 18.9 33.3 17.5 17.2 30.3 30.4 10.7 21.0 15.9 40.2 18.4 15.2 11.5 19.6 28.3 9.2 21.6 62.8 18.1 22.1 20.7 22.2 13.2 2.9 12.1 17.5 10.0 20.5 13.7 14.8 11.5 16.9 13.4 15.5 14.5 15.5 17.5 13.6 15.0 12.0 11.6 5.5 21.5 16.4 10.7 19.9 10.6 22.3 26.0 22.3 35.3 19.4 20.0 16.3 20.4 16.4 14.4 20.8 36.6 14.1 25.2 22.7 49.3 31.3 33.1 16.0 19.4 24.4 25.5 71.0 23.2 38.2 10.6 44.7 31.6 46.7 29.7 65.7 31.3 25.3 25.3 21.2 39.2 30.2 34.0 44.8 29.8 9.6 30.2 21.3 18.6 65.9 34.9 46.4 36.1 52.6 37.4 37.8 36.1 45.3 29.9 72.8 32.6 26.6 43.8 25.4 41.9 24.5 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023265-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 44.8;Syncytiotrophoblasts: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 41.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 5.4 1.4 1.1 13.5 5.1 25.9 3.3 3.8 1.1 18.0 6.4 0.3 34.8 3.7 42.3 29.6 11.7 6.0 5.2 1.9 1.2 2.3 3.5 3.2 6.7 12.8 1.2 0.3 4.7 4.0 10.2 5.8 50.7 1.2 11.5 4.8 2.2 6.3 22.4 1.2 5.1 6.1 19.1 1.5 8.5 4.7 5.2 0.8 44.7 2.3 6.8 10.2 18.0 6.6 8.4 6.2 26.4 11.6 22.0 13.3 10.2 9.1 3.2 0.4 0.0 1.5 1.4 21.0 0.3 1.1 0.1 0.1 8.4 8.3 12.5 5.7 2.0 6.5 10.4 23.4 14.7 0.0 10.8 19.1 18.0 7.9 7.9 1.4 37.6 1.5 2.0 8.8 0.0 9.9 4.4 4.1 17.2 8.0 11.8 3.5 8.1 38.7 35.0 18.8 6.2 1.2 28.0 11.6 16.1 9.5 14.8 7.8 8.6 5.5 5.0 0.2 17.0 6.4 9.9 0.1 3.8 4.0 11.4 13.5 9.1 14.2 13.9 3.4 41.0 1.9 26.4 5.1 16.6 13.3 6.7 13.0 8.4 9.1 11.3 6.2 7.3 11.8 12.2 10.0 22.0 11.6 2.3 4.0 10.2 1.1 5.1 3.8 1.1 1.2 2.3 1.2 0.3 1.2 0.8 20.8 14.1 8.6 27.8 0.0 0.0 1.1 5.1 12.0 14.8 10.4 0.0 44.8 3.3 4.4 0.4 0.4 0.9 0.0 6.3 28.5 4.9 17.5 10.5 3.0 10.7 0.0 1.2 0.6 10.1 0.0 3.1 7.2 0.0 9.0 6.4 0.0 8.6 3.5 2.1 1.2 0.0 6.5 2.9 1.1 2.3 0.0 49.4 17.5 6.3 15.3 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98401403-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.3;granulocytes: 9.0;monocytes: 8.7" "Cell line enhanced" "Detected in many" "A-431: 37.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" NA NA "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavorable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 16.5 16.6 6.5 8.1 12.4 2.5 20.5 2.6 10.6 17.2 13.1 10.5 14.2 4.6 22.2 13.1 9.0 16.0 12.6 10.0 7.4 4.1 14.7 12.0 16.2 10.8 12.8 3.6 22.8 10.7 15.1 18.9 53.1 9.9 15.0 6.0 8.2 10.8 16.4 11.6 10.0 10.8 23.5 12.9 8.2 9.5 10.1 11.4 3.4 10.6 7.9 5.9 16.4 24.3 1.9 8.3 9.0 8.7 1.8 1.8 2.9 37.3 7.0 7.5 9.8 24.2 12.1 7.5 13.0 11.7 12.2 10.6 5.2 15.9 0.0 11.4 12.9 6.4 15.1 5.2 11.2 19.7 9.0 6.6 10.0 3.5 3.5 8.3 3.3 8.7 8.0 19.4 6.2 17.0 8.0 5.2 5.9 4.2 5.4 8.8 4.7 8.3 4.0 2.2 25.8 2.7 7.4 6.4 3.2 13.8 4.7 1.9 4.3 8.3 9.6 8.0 10.0 7.9 5.4 3.9 8.2 5.2 12.4 7.2 4.3 6.5 2.7 7.4 4.2 13.0 2.1 8.6 4.5 1.3 8.7 1.4 1.9 0.8 1.8 8.3 1.3 1.1 0.7 9.0 1.8 5.4 3.4 0.1 2.9 6.5 12.4 2.6 10.6 7.4 4.1 12.8 3.6 9.9 11.4 35.7 32.0 4.7 38.6 38.8 6.0 15.1 22.9 33.5 42.1 27.9 13.7 36.5 19.9 17.3 118.9 30.2 17.6 0.0 16.5 49.2 41.3 37.6 16.2 18.4 16.1 9.5 8.7 22.1 14.6 63.7 84.3 20.2 23.6 7.2 7.6 15.1 19.7 9.5 69.6 20.3 14.2 38.8 39.6 17.0 11.9 35.4 54.1 8.2 9.3 31.1 STK31 "SgK396, TDRD8" ENSG00000196335 "Serine/threonine kinase 31" Q9BXU1 7 23710167-23832513 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 56.0" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 163.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "CACO-2: 20.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023194 Enhanced NA NA "HPA023194: AB_1857590" "unprognostic (4.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.50e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.42e-3)" "unprognostic (2.92e-1)" "unprognostic (1.29e-6)" "unprognostic (7.83e-2)" "unprognostic (9.21e-3)" "unprognostic (1.46e-1)" "unprognostic (3.65e-1)" 0.1 0.0 0.1 0.1 0.7 0.0 0.1 0.8 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 56.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 20.1 2.5 0.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.1 0.2 0.0 0.1 0.1 0.1 0.1 3.0 1.4 0.0 0.2 0.1 1.7 0.4 2.5 6.7 4.5 0.0 0.0 0.5 0.0 0.2 16.5 0.0 0.3 0.0 0.6 0.1 0.0 0.3 0.0 0.8 0.2 0.0 1.2 0.0 0.0 12.3 3.1 0.0 0.0 0.0 0.2 1.3 0.4 0.8 2.8 0.0 1.2 0.0 0.0 163.1 32.6 0.1 0.5 0.0 0.4 0.4 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387852 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.7;brain: 21.1;retina: 31.9" "Cell type enhanced" "Detected in some" 14 "Early spermatids: 5.0;Melanocytes: 15.1;Muller glia cells: 4.6" "Cancer enhanced" "Detected in many" "melanoma: 11.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.2" "Group enriched" "Detected in some" 5 "RT4: 9.8;SK-MEL-30: 34.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 2.1 19.7 4.8 1.3 7.1 0.4 2.3 21.1 7.7 1.2 1.8 6.2 0.6 1.2 1.6 5.6 1.0 1.3 4.3 1.6 4.9 12.6 6.3 0.6 2.1 0.5 12.1 2.2 5.1 4.2 0.4 8.5 0.7 20.7 2.1 1.1 31.9 1.2 1.8 0.6 2.9 1.1 1.4 12.4 0.8 1.4 2.1 6.9 0.0 15.7 0.5 0.5 4.1 2.1 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 3.8 9.8 0.9 0.4 0.0 0.1 34.7 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.4 1.1 0.2 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 4.8 7.1 21.1 2.3 4.9 12.6 12.1 2.2 20.7 6.9 0.0 1.6 0.0 0.2 1.3 1.2 0.4 0.0 0.0 1.2 1.8 0.0 0.0 1.7 1.2 5.0 0.0 0.0 0.0 2.4 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.9 0.0 15.1 0.0 0.0 4.6 4.1 0.0 3.9 3.0 0.9 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.6 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051442-5500998 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.6;lymphoid tissue: 33.6" "Cell type enhanced" "Detected in some" 25 "Distal tubular cells: 14.9;Early spermatids: 83.1;Late spermatids: 31.4;Proximal tubular cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive B-cell: 1.3;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.3;dendritic cells: 3.5" "Cell line enhanced" "Detected in some" "GAMG: 11.9;HUVEC TERT2: 11.7;REH: 10.3;U-2197: 18.7;WM-115: 47.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: AB_1858913" "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 5.2 0.8 6.0 2.1 4.8 2.3 7.3 1.0 5.8 6.0 2.1 5.2 1.6 1.2 5.7 1.6 2.3 2.5 4.7 0.9 4.5 7.6 23.6 0.5 1.3 2.8 5.3 2.2 1.2 4.9 0.8 0.8 5.1 4.2 2.3 2.2 3.0 2.9 1.9 2.1 3.6 1.6 7.0 3.9 0.6 9.5 7.1 2.9 33.6 2.8 2.1 1.9 4.2 6.1 1.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 5.8 0.3 0.0 0.2 0.4 0.0 4.0 0.5 2.7 0.1 0.0 0.0 0.0 0.9 8.2 11.9 0.0 0.6 0.0 1.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.1 11.7 0.6 0.0 0.0 1.4 0.0 0.0 0.8 1.7 0.0 0.0 10.3 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 3.5 0.3 0.0 0.0 3.0 0.0 1.2 18.7 0.0 0.4 0.0 0.0 0.0 0.0 47.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.0 4.8 1.0 5.8 4.5 7.6 5.3 2.2 4.2 2.9 0.0 0.6 0.0 0.1 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.8 83.1 1.6 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 31.4 1.4 0.9 5.0 0.0 0.0 0.0 0.3 0.0 1.1 13.3 0.0 0.0 0.3 0.9 3.0 0.9 0.0 0.0 0.0 0.0 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017894 Uncertain NA NA "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 6.8 8.2 23.5 6.4 23.5 6.1 7.1 8.3 31.6 4.1 4.9 6.3 6.0 5.0 4.6 15.5 3.4 9.4 7.8 7.0 17.9 12.8 6.3 4.2 7.3 8.5 9.2 16.1 5.8 7.0 6.2 6.7 4.8 7.7 4.6 4.7 3.2 5.6 5.5 11.3 7.1 4.7 4.9 7.7 10.7 4.8 26.1 8.1 8.7 4.9 3.0 6.1 4.6 3.6 5.5 14.5 25.0 11.2 3.2 4.9 3.6 32.1 21.1 6.5 16.3 9.1 11.6 1.3 6.8 5.3 8.6 11.1 4.7 22.5 7.1 5.1 7.8 10.9 7.4 9.4 2.7 8.4 4.2 15.1 4.1 21.6 22.3 11.5 3.7 15.5 8.7 10.3 7.8 8.9 11.0 7.5 12.1 7.2 5.0 9.2 9.7 4.7 14.2 4.2 5.9 15.4 5.7 4.1 2.2 11.2 5.6 17.0 13.3 4.8 4.5 9.5 4.0 5.2 9.0 5.0 7.1 7.1 8.9 5.3 9.3 1.7 17.7 15.5 3.6 3.4 25.0 10.7 9.2 3.5 11.2 4.5 3.6 2.9 4.0 14.5 5.5 3.6 2.9 1.4 3.2 9.5 8.3 4.9 3.6 23.5 23.5 8.3 31.6 17.9 12.8 9.2 16.1 7.7 8.1 0.0 11.1 5.2 5.5 4.6 8.8 2.9 2.5 14.7 5.7 12.2 11.8 2.8 16.6 5.0 222.3 8.3 2.6 0.0 7.5 2.0 7.3 7.5 15.1 4.9 13.1 35.0 18.4 11.1 20.5 53.0 8.3 18.4 11.8 6.4 5.5 7.3 6.0 4.0 6.3 9.7 14.6 6.5 5.3 31.4 17.2 4.4 1.3 9.2 7.9 6.2 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.4" "Cell type enhanced" "Detected in many" 12 "Ciliated cells: 245.0;Late spermatids: 113.1;Rod photoreceptor cells: 83.4;Spermatocytes: 126.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 7.1;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 7.1" "Cell line enhanced" "Detected in many" "Daudi: 14.0;hTERT-RPE1: 14.2;Karpas-707: 13.1;SCLC-21H: 14.7;U-251 MG: 14.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: AB_2683257" "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favorable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 0.9 6.1 4.7 1.6 7.5 1.1 0.6 6.1 4.4 5.4 5.3 6.8 7.7 2.6 9.6 15.3 2.3 30.7 4.5 11.4 6.6 6.1 7.7 0.4 5.3 2.3 4.9 2.7 10.3 4.6 20.4 29.9 0.3 17.7 5.3 1.3 14.8 1.6 8.9 2.6 0.3 2.5 7.0 6.7 1.2 4.4 34.4 4.6 4.5 14.6 1.5 1.8 3.7 1.4 7.1 0.7 0.0 0.0 0.2 1.4 0.3 0.0 2.0 9.7 0.0 0.0 0.0 0.0 1.7 1.9 4.2 3.9 1.1 0.0 14.0 7.3 0.3 5.5 0.0 4.3 1.3 3.7 0.0 11.9 0.0 2.6 3.3 1.6 7.8 0.0 0.4 0.0 0.1 0.0 14.2 0.3 6.9 0.0 13.1 0.1 0.0 0.2 0.0 6.9 0.0 0.0 5.2 1.3 8.8 3.8 0.0 14.7 3.9 0.0 0.0 0.1 2.7 0.0 0.8 0.0 0.0 6.6 0.1 14.8 3.1 12.4 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.1 0.0 1.4 0.0 4.4 0.0 1.1 0.0 0.2 0.0 0.7 0.2 0.3 4.7 7.5 6.1 4.4 6.6 6.1 4.9 2.7 17.7 4.6 17.9 12.6 5.4 1.1 0.0 19.2 34.4 10.2 245.0 47.8 19.2 66.8 0.1 3.3 7.5 72.9 1.3 0.0 0.0 4.4 2.7 0.3 0.2 1.1 0.0 0.2 1.6 8.7 0.0 0.0 113.1 4.0 0.4 0.0 0.0 1.3 30.6 4.5 0.0 15.9 11.9 83.4 0.0 0.2 126.9 25.1 0.0 0.0 0.0 2.9 0.0 STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101611-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 27.8;testis: 37.6" "Cell type enhanced" "Detected in many" 18 "Early spermatids: 169.1;Horizontal cells: 278.1;Late spermatids: 665.5;Muller glia cells: 155.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Nucleoplasm, Nuclear bodies" "HPA026452: AB_2671861, HPA051673: AB_2681569" "unprognostic (2.25e-2)" "unprognostic (2.97e-1)" "unprognostic (2.87e-2)" "unprognostic (1.30e-2)" "unprognostic (3.25e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (9.46e-6)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (4.39e-2)" "unprognostic (1.74e-1)" "unprognostic (4.67e-1)" "unprognostic (1.40e-1)" "unprognostic (4.99e-2)" 5.3 6.0 10.3 3.6 14.3 4.3 5.1 6.1 13.7 3.7 4.3 3.1 2.5 4.2 4.5 3.5 8.0 5.1 4.3 5.2 5.9 4.8 4.4 5.7 4.2 3.3 4.4 7.6 3.9 5.9 5.3 6.5 3.5 4.0 3.8 5.2 27.8 6.1 4.0 3.5 6.3 4.6 4.9 4.5 4.1 4.1 37.6 4.4 1.7 5.4 6.1 4.5 4.1 3.7 1.8 2.0 3.2 1.4 0.8 2.7 1.2 15.1 12.9 10.0 17.2 4.6 6.4 12.2 6.2 7.7 8.3 8.6 16.9 11.8 10.4 5.1 7.7 13.0 22.9 11.8 14.3 9.5 4.1 5.6 9.9 4.5 18.3 5.9 8.9 4.6 5.5 12.6 13.3 11.5 7.7 7.9 10.1 9.5 8.6 5.4 6.7 11.1 12.6 18.6 12.1 8.7 9.7 9.0 6.6 7.5 15.2 16.7 8.1 11.1 19.9 9.9 12.2 9.8 8.9 6.6 14.3 9.8 7.1 9.8 7.6 9.8 7.3 7.6 9.7 6.2 0.0 1.2 0.7 1.9 1.0 2.5 1.7 2.7 1.3 2.0 1.8 2.6 2.2 3.2 0.8 1.4 1.7 1.3 1.2 10.3 14.3 6.1 13.7 5.9 4.8 4.4 7.6 4.0 4.4 11.9 9.8 1.9 4.0 10.3 110.1 11.0 0.0 0.0 6.8 3.5 141.4 6.0 1.7 5.5 169.1 7.7 8.1 0.0 5.9 9.9 6.4 5.1 9.2 7.8 5.0 278.1 5.8 4.3 6.0 665.5 6.4 3.9 6.8 1.8 7.6 155.8 8.1 11.5 5.6 3.1 88.5 0.0 4.6 14.9 11.5 10.3 4.8 6.4 9.9 5.1 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672026-218702716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.2" "Cell type enhanced" "Detected in many" 8 "Ciliated cells: 20.1;Cone photoreceptor cells: 35.3;Spermatocytes: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 4.8 10.0 7.5 4.7 11.4 2.0 6.4 7.9 11.1 9.1 7.4 7.0 11.9 4.1 14.4 13.3 5.0 13.9 9.8 3.3 6.3 3.5 10.1 4.4 6.9 3.9 2.3 6.6 13.6 9.7 12.3 23.2 3.9 7.6 9.5 6.3 9.3 7.3 8.3 3.3 4.6 5.8 7.8 5.5 4.9 7.9 63.2 4.2 3.5 11.4 3.7 5.0 9.3 7.1 1.8 1.6 3.2 1.9 2.2 1.6 1.7 2.5 5.8 12.8 10.9 14.0 10.9 7.9 7.0 5.6 8.9 8.4 7.6 4.2 3.4 9.8 7.3 6.0 5.2 8.8 7.3 7.9 1.4 7.3 3.3 17.6 10.5 6.8 4.6 5.6 11.7 5.5 8.7 6.2 23.8 6.7 4.5 7.6 4.3 7.4 5.9 2.7 5.8 7.7 3.2 3.7 5.1 5.5 3.4 10.9 12.9 10.4 8.9 5.4 8.9 3.6 13.9 9.0 3.8 6.3 12.4 4.6 4.7 4.7 5.5 4.2 1.8 7.7 2.2 5.1 0.0 1.9 3.2 1.5 1.2 0.9 1.8 1.1 1.3 1.6 0.6 1.1 1.6 0.2 2.2 1.4 1.3 1.0 1.7 7.5 11.4 7.9 11.1 6.3 3.5 2.3 6.6 7.6 4.2 8.9 4.6 1.7 1.0 1.0 7.7 2.8 5.1 20.1 1.2 3.5 35.3 1.4 0.0 2.9 11.3 2.1 2.0 0.0 2.2 1.3 1.8 1.3 1.1 4.9 2.3 1.6 2.4 4.3 2.8 4.1 5.5 1.2 0.0 1.0 4.4 5.6 1.9 3.7 4.6 3.3 9.8 6.5 2.1 26.8 8.2 0.9 0.7 1.5 3.8 0.4 STK38 NDR ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547470 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol NA NA Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 19.1 8.4 12.4 39.8 10.0 19.4 32.8 18.8 12.7 16.0 26.3 7.8 14.9 17.0 18.8 16.4 28.1 14.6 18.3 15.3 12.1 7.0 15.0 17.3 21.7 45.9 11.9 6.4 12.3 9.5 7.8 11.0 15.4 9.0 17.0 27.1 11.3 24.8 18.7 14.9 21.8 29.1 28.1 13.1 25.1 16.4 24.4 11.0 34.3 10.6 13.4 28.5 22.4 19.8 10.6 13.1 33.2 30.5 25.8 27.6 22.4 17.8 13.2 14.0 15.1 28.3 21.6 12.2 20.0 16.2 20.8 21.0 10.1 12.3 24.1 15.5 29.7 17.3 19.2 11.6 8.3 24.6 9.8 9.9 17.2 17.2 9.1 14.0 6.5 9.5 14.2 21.9 16.1 10.4 24.0 13.0 12.3 14.0 14.1 29.6 10.7 10.5 17.0 5.8 21.3 11.8 40.8 17.0 6.4 19.7 22.5 16.4 7.8 24.3 11.2 14.0 16.4 12.0 17.2 12.5 16.9 15.0 13.5 12.9 11.8 21.0 17.0 3.8 25.4 16.3 33.2 19.8 15.0 27.6 22.6 21.5 10.6 22.9 24.1 13.1 8.1 20.5 22.3 27.1 25.8 30.5 6.6 21.4 22.4 12.4 10.0 18.8 12.7 12.1 7.0 11.9 6.4 9.0 11.0 17.9 16.5 10.8 8.5 11.9 2.5 15.1 22.9 37.5 50.0 7.0 0.0 11.8 1.7 16.1 5.8 12.4 32.4 0.0 11.2 15.4 19.9 11.5 12.7 13.6 11.7 4.8 13.8 11.1 28.5 4.1 25.0 31.7 16.9 9.0 22.9 6.1 19.6 25.9 28.3 13.6 8.5 12.9 13.7 23.6 9.6 18.4 12.8 23.6 22.1 22.5 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.3;granulocytes: 32.2;monocytes: 13.0" "Cell line enhanced" "Detected in all" "HDLM-2: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol NA NA Cytosol "HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 21.2 8.4 11.0 14.6 10.9 10.9 27.2 9.6 14.6 13.0 26.3 5.7 9.7 8.4 23.9 18.2 16.8 14.8 18.2 30.2 10.9 7.8 8.9 8.5 10.8 7.8 11.1 11.8 9.6 8.9 30.2 15.2 10.6 11.9 15.3 15.0 6.8 14.0 10.9 9.1 10.8 14.6 52.3 17.0 7.6 15.6 7.5 10.1 10.0 8.8 10.5 9.8 21.9 22.7 4.5 19.3 32.2 13.0 4.0 4.0 5.3 4.2 5.8 15.1 6.7 6.9 4.7 11.2 2.7 4.0 1.7 2.5 7.3 3.2 9.9 6.5 2.4 5.2 7.9 6.8 4.7 2.7 57.8 5.6 6.1 7.0 3.6 5.8 15.0 7.1 5.7 4.9 6.4 8.2 11.2 13.9 12.8 7.4 7.8 3.5 3.0 9.8 16.3 17.9 11.2 8.8 3.7 17.6 7.6 2.5 8.1 2.4 8.1 12.2 7.5 4.7 15.4 3.7 5.1 5.4 6.0 5.3 8.6 7.4 2.8 2.8 10.4 3.0 7.0 2.4 6.0 13.0 22.9 4.0 11.1 2.8 4.5 3.1 3.9 19.3 3.4 3.8 3.1 32.2 4.0 8.1 8.2 4.0 5.3 11.0 10.9 9.6 14.6 10.9 7.8 11.1 11.8 11.9 10.1 17.9 14.4 9.8 27.4 31.5 11.3 44.5 10.2 9.4 20.5 8.7 2.0 10.0 8.3 41.2 13.6 21.5 19.7 0.0 35.8 7.9 16.0 21.3 16.3 13.0 27.6 9.5 18.5 18.4 33.1 2.3 6.1 48.1 20.3 45.1 27.7 7.5 51.1 31.7 11.3 10.5 6.4 19.4 50.7 6.5 12.1 28.0 23.2 12.5 20.5 39.1 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168248141 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" 5 "Glandular cells: 65.7;Urothelial cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 6.2 2.1 8.4 4.6 11.0 1.3 3.5 9.3 14.1 4.3 9.1 8.3 1.7 10.5 2.3 4.7 14.1 1.9 5.9 7.6 9.8 7.4 2.9 0.8 2.4 7.3 12.3 9.7 3.2 9.9 5.0 8.2 1.2 14.2 9.9 11.7 7.1 22.8 3.8 2.2 3.4 6.1 4.3 19.0 2.5 11.2 35.5 5.5 7.2 2.2 1.8 8.0 5.6 5.3 0.7 1.0 0.0 0.7 1.9 3.4 0.5 6.7 4.1 15.5 4.9 9.5 14.1 1.5 17.0 12.5 11.4 10.6 0.0 22.0 18.7 4.7 11.0 9.9 17.7 9.9 12.4 14.3 5.9 6.1 7.7 4.5 13.8 17.8 10.4 0.8 9.7 17.7 13.5 14.1 13.8 7.7 14.7 0.1 0.0 23.9 3.9 18.1 3.7 10.7 14.0 8.6 25.8 6.1 1.5 8.6 16.8 22.9 9.7 5.9 0.9 6.9 7.7 3.1 7.6 7.3 13.8 4.3 9.7 11.1 0.0 0.0 15.0 10.5 9.3 9.3 0.0 0.7 0.0 2.5 0.4 1.3 0.7 1.9 3.4 1.0 0.7 0.4 2.0 0.0 1.9 0.3 0.3 3.3 0.5 8.4 11.0 9.3 14.1 9.8 7.4 12.3 9.7 14.2 5.5 3.0 12.3 0.8 21.2 3.4 13.8 25.8 22.9 6.7 7.9 5.2 15.7 0.1 18.3 9.7 21.3 3.5 23.2 0.0 19.9 0.0 7.3 65.7 0.0 0.0 3.5 19.1 21.9 3.1 5.1 13.5 9.5 5.2 16.9 1.0 13.9 26.9 26.4 17.3 10.6 3.8 25.3 6.5 7.2 19.9 7.7 3.9 0.2 15.2 20.4 55.5 STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966474-45079959 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "monocytes: 469.7;T-cells: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: AB_2144632, HPA015270: AB_1854150" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (8.83e-2)" "unprognostic (8.49e-3)" "unprognostic (2.95e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (1.18e-2)" 9.5 8.8 10.4 24.5 11.5 39.5 8.1 7.5 13.4 7.8 8.6 10.3 5.4 8.1 9.3 6.5 8.9 7.3 9.4 6.1 9.3 8.8 6.3 7.4 18.8 30.6 10.5 9.1 8.3 6.4 5.9 9.3 8.2 7.7 7.5 10.6 7.4 9.3 8.7 4.2 11.4 16.1 8.2 12.0 29.1 9.6 7.4 9.6 32.3 8.0 4.9 36.6 11.5 8.7 10.8 6.9 40.6 13.3 10.3 14.5 7.9 11.8 8.0 10.3 7.3 6.3 7.9 7.1 10.5 16.0 17.7 16.1 22.7 6.5 28.9 9.1 7.4 14.9 12.6 10.8 14.0 22.8 12.9 5.7 21.1 11.7 16.0 11.1 27.1 30.0 6.4 11.6 16.6 18.2 8.9 6.5 19.6 9.7 16.7 8.9 9.3 20.2 18.3 6.2 7.7 5.5 13.1 11.3 13.4 6.5 8.1 4.9 6.0 15.5 9.0 11.8 8.2 8.2 17.1 8.3 13.4 13.0 15.4 12.0 21.8 17.1 32.3 13.1 13.0 9.8 24.4 7.6 20.5 14.5 7.7 14.4 10.3 13.8 13.3 6.9 10.8 14.3 11.9 40.6 10.3 13.3 3.9 13.3 7.9 10.4 11.5 7.5 13.4 9.3 8.8 10.5 9.1 7.7 9.6 14.9 24.0 181.6 40.4 49.5 24.2 7.0 15.3 16.0 18.2 40.1 49.1 20.3 8.3 14.1 4.8 32.3 20.5 0.0 15.3 21.4 24.3 25.1 129.5 19.1 53.0 41.3 24.6 22.7 103.3 3.6 21.0 108.8 126.5 469.7 17.4 20.3 16.0 25.9 15.9 10.9 64.0 12.9 30.2 36.4 43.8 46.3 16.2 231.2 17.4 36.3 STUB1 "CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1" ENSG00000103266 "STIP1 homology and U-box containing protein 1" Q9UNE7 16 680224-682870 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037202, CAB037209, HPA041222, HPA043531" Enhanced Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB037202: AB_1840759, CAB037209: AB_1840757, HPA041222: AB_2677368, HPA043531: AB_2678533" "unprognostic (5.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.90e-1)" "unprognostic (3.89e-1)" "unprognostic (9.00e-2)" "unprognostic (3.06e-1)" "unprognostic (4.09e-3)" "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (8.31e-2)" "unprognostic (5.78e-2)" "unprognostic (6.77e-2)" "prognostic favorable (6.49e-9)" "unprognostic (9.67e-2)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-1)" 29.4 43.7 52.2 20.1 43.2 19.3 40.5 39.1 53.3 25.1 24.8 18.1 27.6 24.1 19.7 34.9 35.2 31.1 25.5 45.2 43.2 38.6 24.0 25.9 23.6 28.1 42.0 42.5 29.4 43.4 39.8 27.2 12.1 35.0 23.4 17.7 18.6 37.7 29.7 92.5 33.7 20.9 24.5 34.5 19.7 22.8 13.8 25.4 13.1 29.1 30.2 19.4 22.3 35.9 18.0 21.0 19.4 14.5 10.3 16.9 6.9 18.0 24.5 16.6 28.0 37.9 34.7 9.5 24.6 29.0 29.3 26.1 30.4 23.1 18.3 17.5 41.3 18.9 15.4 20.4 37.1 12.2 20.1 67.6 11.4 35.3 25.4 54.6 19.1 22.7 41.3 39.8 34.3 21.7 23.1 29.6 17.9 18.3 30.6 45.3 71.5 20.7 18.8 18.5 29.0 26.8 32.1 10.9 45.0 39.1 18.0 28.9 23.5 19.8 43.5 30.9 11.0 27.7 36.7 23.4 26.9 23.6 22.2 29.6 30.3 31.3 29.5 21.2 17.3 30.3 11.9 14.5 19.4 16.9 11.9 15.4 18.0 14.6 14.7 11.7 17.3 13.6 12.9 14.0 10.3 12.4 21.0 12.2 6.9 52.2 43.2 39.1 53.3 43.2 38.6 42.0 42.5 35.0 25.4 35.7 24.7 77.5 88.5 102.0 92.7 1.1 101.9 28.1 22.7 123.9 49.1 67.7 242.1 127.5 6.6 66.9 130.5 23.3 147.7 75.3 72.2 130.8 20.7 112.4 99.1 79.4 72.9 61.4 56.4 11.8 100.9 74.8 111.3 200.2 92.2 123.1 150.1 93.1 105.4 269.6 58.7 71.1 101.9 23.5 69.3 105.3 84.2 61.0 87.3 99.9 STYXL1 "DUSP24, MK-STYX" ENSG00000127952 "Serine/threonine/tyrosine interacting like 1" Q9Y6J8 7 75996338-76048004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050261 Uncertain NA No "HPA050261: AB_2681066" "unprognostic (6.24e-2)" "unprognostic (1.12e-1)" "unprognostic (7.21e-2)" "unprognostic (1.81e-2)" "unprognostic (2.88e-3)" "unprognostic (9.33e-2)" "unprognostic (1.50e-3)" "unprognostic (4.77e-2)" "unprognostic (8.01e-2)" "unprognostic (4.02e-2)" "unprognostic (4.47e-3)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (3.17e-2)" "unprognostic (2.28e-1)" "prognostic favorable (8.22e-4)" 9.4 19.2 16.0 10.2 23.1 12.7 17.5 12.8 19.8 15.7 15.1 19.6 13.9 10.5 10.3 21.0 21.1 28.2 9.4 13.2 16.6 12.1 14.8 20.1 11.3 13.7 20.9 13.5 15.4 30.0 15.9 19.9 24.6 16.8 16.6 20.1 12.2 16.0 13.9 12.4 19.3 10.3 14.0 17.0 17.4 14.0 25.0 19.7 20.8 19.9 12.1 19.5 14.8 14.6 19.7 23.0 30.8 29.3 24.7 22.1 17.4 19.8 10.6 8.4 11.2 13.3 14.5 8.7 9.0 12.8 14.6 14.5 12.3 18.1 4.6 4.5 11.8 23.1 8.8 13.5 17.9 21.2 14.8 6.0 5.6 5.0 11.0 18.9 7.8 10.3 14.0 21.1 17.4 43.9 18.8 14.1 7.0 18.1 14.0 13.0 16.0 3.1 33.5 7.1 19.2 25.7 11.9 7.0 12.2 18.5 13.0 11.0 11.4 8.4 19.2 22.4 21.9 21.1 15.1 7.0 12.6 5.3 13.8 12.7 15.2 9.6 15.7 11.1 15.0 19.5 30.8 29.3 25.8 13.7 25.3 15.2 19.7 13.2 15.2 23.0 15.6 11.7 13.2 24.6 24.7 23.7 15.1 22.1 17.4 16.0 23.1 12.8 19.8 16.6 12.1 20.9 13.5 16.8 19.7 20.8 10.4 12.3 13.2 6.5 5.6 15.4 10.2 54.9 30.7 10.4 0.0 25.9 33.2 13.9 68.8 7.8 14.4 0.0 22.7 20.3 7.6 16.5 10.4 15.5 26.7 3.2 19.4 12.9 23.8 50.5 10.6 18.9 3.3 32.5 24.6 18.8 19.6 40.3 9.6 16.3 8.9 6.5 6.1 22.2 12.6 8.7 37.6 9.6 17.7 15.9 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134533 "Enzymes, Predicted membrane proteins" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Hepatocytes: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favorable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 13.8 20.8 11.0 33.0 15.3 13.8 14.9 13.3 19.3 15.1 14.2 21.0 20.2 13.2 16.0 21.1 14.4 16.1 15.3 12.9 11.3 10.0 16.4 78.0 14.2 28.9 18.2 8.7 17.1 68.1 24.4 21.0 20.9 14.4 15.0 15.4 13.3 48.9 22.6 16.7 14.4 19.6 13.6 12.8 27.1 18.3 14.4 14.9 10.3 23.5 8.0 42.2 13.3 12.6 17.5 13.0 11.6 5.4 2.2 5.5 3.8 8.6 11.1 6.7 9.0 17.1 9.8 6.7 9.0 9.3 11.5 8.2 6.0 15.2 49.0 12.3 11.5 15.2 13.5 7.3 9.1 9.5 7.6 5.5 7.7 12.9 13.4 20.8 11.5 14.0 12.4 16.5 10.1 23.0 10.3 7.4 5.2 9.6 25.1 6.7 12.9 5.0 8.3 7.2 9.1 7.7 8.5 5.7 19.7 7.2 8.6 4.4 9.0 8.3 20.7 14.5 6.2 15.4 7.6 7.1 8.0 5.3 14.3 6.0 50.2 34.7 56.6 10.8 5.9 8.9 11.6 5.4 9.3 5.5 3.3 5.0 15.4 3.9 5.1 3.1 17.5 2.9 3.0 5.2 2.2 3.2 13.0 3.6 3.8 11.0 15.3 13.3 19.3 11.3 10.0 18.2 8.7 14.4 14.9 14.9 21.3 22.2 6.0 15.7 10.2 3.4 33.1 9.4 20.5 10.4 31.4 11.5 1.7 10.5 4.3 8.3 15.8 23.3 16.3 12.6 12.1 13.4 1.1 60.4 13.6 12.7 8.1 14.1 14.8 3.5 19.0 11.6 11.8 6.4 25.0 10.8 17.1 12.4 12.4 7.2 17.1 12.9 7.5 21.0 10.9 14.1 35.8 10.2 14.5 11.6 TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366239-71532374 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dystonia, Mental retardation, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 76.6;Erythroid cells: 70.0;Rod photoreceptor cells: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA001075, CAB016283" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB016283: AB_671202, HPA001075: AB_1080179" "unprognostic (2.95e-2)" "unprognostic (1.77e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "prognostic favorable (6.54e-4)" "unprognostic (2.68e-2)" "unprognostic (3.43e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (1.14e-2)" "unprognostic (1.41e-1)" "unprognostic (1.82e-2)" "unprognostic (2.56e-2)" 20.1 16.2 15.0 17.1 19.8 16.3 17.7 20.7 18.0 20.7 15.5 23.8 17.1 10.0 25.4 17.1 14.4 19.1 16.1 12.9 15.4 12.0 11.9 12.9 13.8 17.8 18.5 16.5 23.9 17.5 25.5 19.3 15.4 17.3 16.9 15.4 20.8 14.5 16.1 19.6 16.8 17.1 18.3 17.2 21.3 15.8 12.2 21.3 19.4 20.1 12.0 18.7 18.4 15.8 5.0 4.7 5.2 4.8 4.2 4.9 1.8 11.4 10.0 11.4 7.7 9.1 15.9 7.1 8.6 8.0 9.0 7.5 7.5 6.9 10.7 7.3 9.5 8.0 10.9 15.9 6.8 11.6 7.1 13.9 12.8 13.1 7.3 6.6 24.2 12.3 9.2 6.9 9.7 18.4 8.1 9.4 8.3 17.3 26.0 9.1 8.1 13.4 10.7 13.1 12.8 13.1 12.3 23.2 13.1 6.1 14.9 6.1 9.4 23.9 8.4 10.5 9.4 6.1 12.9 11.8 10.7 9.0 8.6 5.9 11.2 10.3 13.8 5.9 19.5 7.9 4.4 4.1 1.1 4.4 2.8 3.8 3.0 4.6 4.5 4.7 5.0 4.4 4.9 5.2 4.2 4.8 3.5 3.1 1.8 15.0 19.8 20.7 18.0 15.4 12.0 18.5 16.5 17.3 21.3 29.8 25.3 10.9 8.1 10.5 33.8 14.8 5.1 13.4 34.2 3.5 76.6 6.7 1.7 5.1 2.0 23.9 8.4 70.0 6.0 4.9 10.4 8.4 22.0 12.1 7.7 15.9 10.9 19.0 15.4 1.8 20.4 17.0 5.0 6.4 15.4 18.7 6.4 14.0 20.8 3.6 71.6 0.0 14.2 6.0 8.9 15.2 4.8 13.8 14.6 7.6 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390464-29551904 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Uncertain Vesicles NA NA 13000 Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 17.2 11.5 19.1 11.9 25.0 12.7 13.3 20.1 24.4 15.8 11.9 22.2 7.9 7.1 14.9 10.8 12.7 11.0 11.6 15.3 18.7 15.5 13.6 10.6 13.2 11.1 30.0 17.6 13.5 9.3 31.7 13.7 14.3 21.8 12.0 10.7 10.9 11.1 13.3 15.0 13.8 9.8 17.7 21.0 13.0 10.8 14.3 23.5 11.7 17.7 6.0 11.2 14.5 17.1 2.4 4.8 5.5 2.1 1.4 3.0 0.9 13.7 24.5 19.3 8.2 14.4 18.3 8.1 13.0 13.9 11.9 12.6 13.2 4.8 8.5 12.7 21.1 12.8 10.8 17.6 9.0 21.6 17.8 13.0 13.6 14.1 7.0 10.5 15.0 12.6 12.0 11.6 17.6 18.1 12.6 16.3 8.7 13.9 7.8 15.6 9.2 11.8 5.6 8.2 7.6 6.3 10.9 27.2 5.9 11.3 19.9 10.7 13.1 22.3 20.9 13.4 20.4 15.1 13.9 23.6 18.3 14.9 16.0 18.2 7.2 15.4 9.9 13.4 9.4 16.5 1.7 1.9 1.5 2.0 2.1 1.6 1.6 2.0 2.4 1.7 2.4 3.0 2.2 5.5 1.4 1.9 4.8 1.2 0.9 19.1 25.0 20.1 22.7 18.7 15.5 30.0 17.6 21.8 23.5 44.7 47.4 18.4 23.0 39.5 53.4 78.7 30.6 24.1 38.7 43.6 92.3 15.2 13.3 23.9 10.7 41.3 21.4 0.0 20.9 13.5 47.9 34.5 27.7 23.6 25.9 49.3 36.1 51.5 65.2 12.5 36.8 44.8 38.8 23.4 20.1 35.6 30.2 21.2 50.9 15.9 48.3 25.8 36.8 55.4 33.6 40.1 31.5 19.8 18.0 38.2 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973641-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Ito cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favorable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 27.8 24.1 26.2 15.1 26.7 12.3 17.7 29.2 30.6 13.5 13.6 21.5 11.8 18.5 16.8 13.0 12.4 14.1 15.1 17.6 25.0 18.2 13.9 10.4 23.0 14.4 22.1 22.7 15.8 16.3 26.2 18.7 22.5 20.7 13.6 9.6 15.0 17.1 15.9 22.8 20.0 19.3 14.8 14.9 26.3 16.0 21.2 20.2 14.0 15.9 9.8 11.5 12.8 18.0 2.6 3.3 4.8 2.8 2.0 3.2 2.0 11.2 21.5 11.8 18.6 13.9 9.3 18.1 20.7 11.1 14.0 13.1 17.2 15.1 12.2 17.6 14.9 9.4 17.6 10.7 10.4 7.6 18.9 22.7 13.1 21.7 17.2 10.1 12.9 25.3 10.9 9.1 14.9 6.0 9.8 23.4 11.7 11.8 12.4 13.3 20.8 15.0 18.3 11.4 8.4 14.5 27.7 17.1 11.3 8.8 10.6 13.9 11.2 11.8 15.8 6.2 7.9 19.8 14.6 32.6 24.2 11.2 17.1 11.9 18.1 11.6 11.5 14.8 14.8 17.6 1.3 2.8 1.5 2.9 2.7 3.1 2.0 2.9 2.6 1.8 2.6 1.6 1.4 4.8 2.0 1.4 3.3 3.2 2.0 26.2 26.7 29.2 30.6 25.0 18.2 22.1 22.7 20.7 20.2 8.9 11.5 2.2 4.2 9.5 13.3 8.1 5.1 4.0 7.9 8.7 37.3 6.7 1.7 7.6 3.1 27.6 23.3 0.0 10.2 4.8 9.3 5.8 3.5 9.7 8.4 9.5 12.6 44.2 12.4 2.1 11.5 5.5 6.8 4.6 14.9 8.7 12.7 14.2 12.0 6.4 19.2 6.5 7.6 21.1 17.2 8.4 10.1 9.2 13.3 5.7 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372945 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Rod photoreceptor cells: 324.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria NA NA Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 14.6 16.2 31.9 24.1 31.0 30.8 14.6 44.3 33.5 11.6 21.2 17.2 10.3 23.1 15.2 11.4 16.0 9.8 16.9 15.1 27.8 31.7 14.0 15.3 19.4 26.3 25.7 20.8 17.5 10.9 20.2 23.6 11.9 20.7 25.6 21.3 12.0 13.6 14.6 18.5 17.0 31.6 15.3 23.7 24.2 20.9 8.9 28.6 28.3 18.1 9.9 26.9 18.5 18.3 20.9 22.4 38.2 37.8 36.4 27.8 17.1 8.3 5.8 4.3 3.8 10.7 13.1 4.9 8.8 10.0 5.1 6.7 2.9 13.0 25.6 2.9 11.7 7.4 7.6 3.7 7.8 8.0 9.2 3.2 30.2 2.9 3.8 12.5 30.9 42.6 8.8 9.4 16.1 23.7 10.8 16.3 15.3 17.5 3.0 9.3 5.9 16.3 20.3 1.7 3.9 3.1 9.5 5.9 2.7 4.8 14.5 0.8 4.3 8.1 3.7 11.2 2.0 7.6 23.2 25.3 8.8 1.5 8.2 7.5 2.9 2.8 20.3 12.5 21.4 11.8 38.2 17.0 37.6 27.8 23.3 26.2 20.9 21.2 24.1 22.4 19.3 18.8 24.5 37.7 36.4 37.8 20.9 19.3 17.1 31.9 31.0 44.3 33.5 27.8 31.7 25.7 20.8 20.7 28.6 32.8 78.2 81.8 42.2 31.3 72.1 47.4 63.7 6.7 30.7 43.6 200.3 29.7 59.7 35.4 11.4 29.2 94.6 23.3 52.0 83.1 34.9 47.7 159.8 52.0 71.7 38.1 24.1 26.4 84.7 8.2 35.9 117.0 33.7 141.5 60.6 40.4 64.9 98.2 44.9 27.2 324.3 45.3 40.5 20.5 22.8 27.5 36.6 86.3 58.2 47.4 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64451880-64502108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease mutation, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA045797: AB_2679457, HPA060211: AB_2684222" "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 19.1 23.3 13.7 16.8 17.1 32.3 19.1 17.8 20.5 14.9 18.3 10.0 14.1 18.0 17.0 15.1 15.3 13.8 15.6 11.7 14.7 15.6 15.4 20.8 17.8 18.3 20.2 13.6 15.6 11.1 13.1 27.2 40.6 21.1 16.3 12.9 10.1 15.0 18.3 24.8 12.1 21.4 17.2 18.8 24.6 14.5 27.9 16.9 3.4 13.3 12.6 16.7 18.4 19.6 9.7 8.2 22.5 11.9 16.3 11.8 5.9 13.4 15.4 8.8 12.8 15.8 16.0 19.4 14.7 21.5 13.9 13.2 8.7 8.2 18.8 12.8 15.9 20.1 12.7 11.3 12.4 16.4 17.3 10.8 20.2 11.2 12.0 17.3 20.6 25.2 12.0 11.3 13.9 13.4 24.1 18.5 7.2 15.4 27.4 17.9 16.4 0.6 16.1 17.6 12.3 9.0 9.6 9.8 18.1 15.1 24.4 7.4 10.7 19.4 20.0 14.3 15.3 20.4 15.0 17.1 12.5 12.1 10.0 14.4 17.4 30.2 18.3 15.8 11.4 16.1 22.5 7.3 16.6 11.0 11.9 11.8 9.7 8.0 11.0 8.2 7.6 2.8 7.1 15.1 16.3 10.6 1.9 9.5 5.9 13.7 17.1 17.8 20.5 14.7 15.6 20.2 13.6 21.1 16.9 17.9 15.6 14.7 23.9 9.7 18.4 10.0 7.6 18.7 19.4 21.0 9.8 24.9 10.0 17.0 24.8 24.1 10.7 0.0 20.6 24.3 13.6 35.1 41.6 14.3 18.1 17.5 16.6 16.5 19.0 20.1 17.8 26.2 13.5 27.9 8.0 13.0 14.3 10.2 19.4 11.6 15.8 25.8 17.8 49.9 12.9 13.0 77.5 25.8 9.3 32.4 TBL1X "EBI, TBL1" ENSG00000101849 "Transducin beta like 1 X-linked" O60907 X 9463295-9741037 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Congenital hypothyroidism, Deafness, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cytotrophoblasts: 65.3;Hepatocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 17.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.3" "Low cell line specificity" "Detected in many" "CAB005363, HPA067703" Approved Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "CAB005363: AB_2240272, HPA067703: AB_2685892" "prognostic unfavorable (8.50e-4)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (2.89e-2)" "unprognostic (2.44e-1)" "unprognostic (1.40e-2)" "unprognostic (2.21e-3)" "unprognostic (3.09e-1)" "unprognostic (2.70e-1)" "unprognostic (3.27e-1)" "prognostic favorable (1.32e-4)" "unprognostic (2.66e-1)" "prognostic favorable (4.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.38e-2)" "unprognostic (3.40e-3)" "unprognostic (1.53e-1)" 6.5 7.1 10.1 6.0 12.3 4.5 8.1 3.3 8.1 21.4 7.9 13.2 18.0 2.1 33.0 26.4 8.3 12.4 6.7 5.2 8.6 9.0 12.5 11.0 5.2 9.5 7.6 6.0 13.8 11.3 21.0 24.3 14.5 7.5 24.7 4.1 9.8 5.5 33.0 4.9 5.8 4.2 22.4 9.0 5.7 7.0 9.9 8.5 14.7 9.4 3.4 7.1 15.3 24.5 3.2 3.1 17.3 4.2 0.3 3.1 1.7 0.0 13.5 8.6 22.9 8.0 8.4 8.5 5.2 11.6 10.0 10.5 10.1 9.3 14.3 0.3 10.3 4.3 3.1 18.8 4.0 14.6 5.9 9.2 9.0 16.5 11.8 11.3 3.2 32.3 7.4 4.7 10.4 5.5 5.4 9.2 7.9 15.7 25.0 5.7 11.4 7.8 12.1 17.1 6.4 14.5 17.6 6.8 17.6 13.5 7.6 11.0 5.0 12.5 3.1 7.4 23.6 6.1 7.0 13.3 3.5 8.7 0.3 2.0 15.3 11.8 11.4 12.9 7.8 3.3 4.4 4.2 4.9 2.1 2.6 1.7 2.0 1.6 1.9 3.1 3.2 3.1 2.8 17.3 0.3 1.7 0.3 2.5 1.7 10.1 12.3 3.3 8.1 8.6 9.0 7.6 6.0 7.5 8.5 0.0 5.0 15.2 9.4 5.8 11.5 9.5 22.9 12.0 6.8 29.6 21.6 65.3 11.6 9.9 0.8 9.4 2.6 0.0 6.7 2.4 10.0 18.9 10.5 59.7 10.0 6.4 21.9 11.6 32.3 1.7 13.3 19.9 5.0 10.8 4.8 38.8 8.5 3.5 26.9 17.0 22.7 0.0 25.9 1.4 17.9 10.8 37.6 10.7 4.7 22.3 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "Transducin beta like 1 X-linked receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 71.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm NA NA Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favorable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 20.7 26.0 27.4 24.3 26.8 27.3 20.3 27.5 28.1 28.9 29.9 22.6 15.4 24.0 23.9 20.5 23.8 21.9 22.7 30.3 26.2 20.7 19.9 21.8 30.8 27.8 21.4 25.9 26.5 19.9 30.6 11.3 24.0 19.7 24.4 23.2 24.7 21.3 17.7 21.1 17.8 24.3 21.9 19.6 24.7 21.3 17.4 22.3 28.4 45.6 14.9 32.1 29.1 25.5 7.4 13.3 12.9 4.6 6.8 8.3 4.1 23.9 12.3 16.0 9.0 13.6 14.8 9.6 7.6 11.8 6.6 9.1 14.1 19.9 24.6 35.9 10.9 17.5 14.8 11.9 15.8 13.3 25.8 3.7 13.8 21.0 8.4 11.7 21.9 8.2 21.8 8.2 9.7 24.1 13.0 10.3 17.3 10.3 43.6 8.5 8.6 20.4 3.0 10.1 15.4 8.3 11.7 20.4 26.2 5.9 34.0 5.8 9.2 10.2 8.0 9.5 10.5 29.3 16.8 15.7 10.8 9.1 6.0 16.4 23.8 30.5 71.1 7.3 16.4 12.3 11.4 3.0 3.8 5.8 4.6 5.1 7.3 5.7 6.6 4.0 7.4 5.0 6.4 12.9 6.8 3.9 13.3 8.3 4.1 27.4 26.8 27.5 28.1 26.2 20.7 21.4 25.9 19.7 22.3 68.5 47.1 43.4 46.9 81.4 116.0 84.2 48.4 61.6 62.6 99.5 117.8 22.3 24.9 43.8 5.7 62.9 42.8 23.3 37.3 28.5 65.8 123.0 24.3 58.7 32.8 109.7 81.9 55.9 85.4 5.2 59.2 54.6 62.4 31.5 74.5 41.8 53.4 23.0 68.6 46.2 81.2 45.3 41.5 8.4 53.9 97.7 23.0 49.8 75.7 61.8 TESK1 ENSG00000107140 "Testis-specific kinase 1" Q15569 9 35605305-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 30.9 19.4 13.5 10.8 20.5 5.6 25.4 13.4 26.4 14.3 15.2 15.0 9.7 13.7 15.3 13.4 11.0 12.0 13.0 12.8 13.7 13.1 10.5 10.0 11.5 10.7 14.1 10.3 17.0 16.0 13.1 15.7 12.3 12.6 15.1 8.8 14.2 14.6 21.0 47.2 13.7 12.7 16.9 7.3 11.0 12.9 28.4 12.9 9.2 13.0 12.3 9.0 16.6 20.9 1.0 2.3 0.3 1.8 2.1 4.9 1.5 9.5 8.9 6.1 10.2 24.6 10.3 7.0 10.9 9.8 10.2 6.5 5.2 2.7 17.4 6.2 10.9 27.1 3.3 3.9 7.9 1.9 11.2 5.2 2.5 8.5 4.5 14.4 2.1 8.4 10.0 12.5 7.9 10.9 10.9 7.1 8.6 2.9 6.3 10.1 10.5 4.8 10.6 3.8 8.8 10.5 7.5 3.7 4.1 7.5 4.4 5.0 6.1 6.2 7.6 4.6 4.4 9.0 3.2 6.2 22.6 9.7 16.2 6.5 3.8 5.4 6.5 16.4 2.5 5.1 0.0 1.8 0.3 3.4 0.4 3.0 0.8 1.4 4.9 2.1 1.0 1.5 1.6 0.0 2.1 0.8 2.3 0.3 1.5 13.5 20.5 13.4 26.4 13.7 13.1 14.1 10.3 12.6 12.9 6.0 7.7 5.9 5.6 12.8 10.4 1.9 5.1 4.0 3.4 7.0 7.9 3.2 1.7 5.6 33.3 8.7 14.2 0.0 9.0 7.2 8.9 13.5 1.1 9.3 13.1 12.7 9.1 4.9 4.1 27.1 11.2 8.4 13.5 2.8 12.4 11.3 8.3 8.2 13.4 6.1 12.2 6.5 7.8 13.0 5.9 12.2 2.7 6.9 6.1 6.8 TESK2 ENSG00000070759 "Testis-specific kinase 2" Q96S53 1 45343883-45491166 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 13.1;RT4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 5.5 3.3 6.1 5.9 17.4 12.6 9.6 7.8 12.6 7.7 8.4 25.7 4.0 11.9 4.7 5.7 9.1 4.1 3.9 5.8 9.6 5.1 3.5 9.7 5.5 6.0 19.2 4.7 14.4 4.6 6.7 4.1 8.3 13.2 22.1 10.1 7.6 11.2 5.7 10.1 17.1 14.8 4.4 18.7 6.3 5.6 11.7 14.8 4.2 5.1 3.2 7.2 8.2 9.7 7.5 2.0 15.9 5.9 1.1 3.7 2.6 1.6 0.0 0.8 0.0 3.2 1.7 13.1 0.6 4.3 1.9 3.2 3.6 1.5 5.3 0.6 1.6 4.9 2.0 3.4 2.7 1.5 3.7 4.3 3.6 1.8 2.7 1.7 1.2 9.9 1.8 2.9 2.1 3.0 2.9 1.5 7.1 0.6 10.9 1.3 0.6 3.0 2.4 3.4 1.5 1.5 4.4 0.1 1.4 1.7 12.8 0.3 1.4 3.4 6.4 12.2 8.1 10.0 1.5 0.0 0.2 2.0 1.6 1.1 7.2 4.2 1.0 1.0 0.0 0.8 9.4 3.8 10.6 2.4 2.8 1.7 7.5 2.2 1.6 2.0 5.7 3.7 2.1 15.9 1.1 5.9 1.1 1.5 2.6 6.1 17.4 7.8 12.6 9.6 5.1 19.2 4.7 13.2 14.8 0.0 3.2 2.4 6.5 6.9 2.3 1.1 5.1 1.4 3.4 0.0 13.7 6.5 0.0 1.0 18.1 2.9 12.4 0.0 2.3 2.5 2.2 12.9 6.9 5.5 5.9 0.0 4.1 1.3 4.6 5.2 2.6 4.5 3.3 2.8 5.3 1.1 1.0 7.4 1.8 0.6 2.8 6.5 4.7 26.8 5.7 7.4 12.4 4.4 4.9 7.3 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 114.1;Late spermatids: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 11.1 6.9 10.3 11.5 14.6 20.0 15.4 12.6 11.3 14.4 20.0 11.0 5.5 7.4 18.8 8.0 13.2 10.9 14.9 9.7 7.8 7.5 16.0 9.8 19.2 18.9 15.8 4.3 13.3 8.8 6.5 13.5 50.9 14.1 12.3 9.2 10.4 10.2 12.2 8.4 6.6 11.0 28.6 17.9 13.9 25.5 11.4 12.4 10.8 7.7 8.1 11.5 13.0 10.2 1.6 2.0 13.1 2.4 4.0 8.3 1.9 3.4 5.2 31.4 9.7 7.3 5.4 4.7 11.7 12.9 11.0 12.3 5.2 2.5 7.6 3.6 9.1 8.7 8.1 10.6 9.1 14.8 19.9 3.3 11.4 5.7 4.6 12.1 7.0 27.9 11.2 9.8 17.1 8.1 6.9 1.9 2.9 15.8 3.2 15.0 5.3 1.0 8.0 6.7 3.2 3.1 2.8 68.5 3.2 2.7 0.8 8.5 9.9 9.1 40.7 12.2 13.5 7.5 9.6 3.6 8.2 7.1 35.0 7.1 3.3 3.3 5.2 17.2 12.1 7.0 13.1 2.4 9.1 8.3 1.6 7.2 1.6 3.6 6.1 2.0 1.3 3.5 6.7 4.9 4.0 1.9 1.4 2.2 1.9 10.3 14.6 12.6 11.3 7.8 7.5 15.8 4.3 14.1 12.4 6.0 9.1 9.3 6.5 20.9 7.2 6.3 5.1 1.4 10.3 57.6 0.0 17.0 0.0 14.1 114.1 14.5 3.3 23.3 27.1 5.9 46.2 13.4 29.9 11.5 43.1 0.0 9.2 8.0 20.9 74.1 8.9 36.3 33.7 19.0 6.6 2.9 25.9 3.5 12.7 12.2 1.6 32.3 22.2 8.0 10.5 14.2 16.2 11.5 7.2 8.4 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606502-30694142 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 14 "Endothelial cells: 188.8;Ito cells: 564.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;ASC TERT1: 82.2;HSkMC: 70.9;LHCN-M2: 67.2;TIME: 61.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 560000 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 91.8 24.6 6.7 24.6 10.3 7.3 88.3 3.6 7.3 36.5 42.6 9.8 18.6 13.2 42.6 23.3 36.2 28.4 42.6 73.5 6.9 5.2 32.6 21.9 52.6 75.7 12.6 3.7 22.2 26.0 17.4 10.3 24.2 9.9 35.2 17.5 27.9 22.5 19.5 34.9 17.0 31.3 37.2 12.0 68.7 26.8 15.4 8.2 19.3 40.9 16.8 26.9 48.0 82.0 5.3 6.8 20.0 6.6 1.4 19.7 3.9 2.5 14.7 0.9 0.0 54.5 82.2 2.5 12.8 18.0 4.4 4.4 3.3 13.6 0.3 46.2 17.1 5.2 5.1 0.6 18.7 7.3 1.0 1.3 1.4 1.7 16.5 23.3 2.3 12.1 70.9 16.6 19.0 18.4 20.2 47.6 1.7 0.3 0.0 67.2 0.2 2.3 1.7 0.4 12.8 5.9 2.1 5.9 0.3 23.6 6.0 0.0 0.9 3.8 1.0 3.6 1.2 0.0 2.5 61.6 21.7 5.4 9.8 4.8 0.5 0.0 2.0 13.0 2.5 8.7 6.9 2.9 20.0 3.5 3.0 3.2 4.0 5.4 4.2 2.6 5.3 19.7 9.1 12.6 1.4 6.6 6.8 1.2 3.9 6.7 10.3 3.6 7.3 6.9 5.2 12.6 3.7 9.9 8.2 134.0 83.8 41.5 14.2 33.2 1.9 64.1 48.4 12.0 53.4 26.2 0.0 5.3 3.3 11.4 2.0 188.8 9.7 0.0 13.8 4.3 48.1 7.3 28.9 45.3 27.1 0.0 8.1 564.1 139.2 2.0 30.5 46.1 28.7 1.8 11.9 0.2 25.3 10.8 44.6 5.6 0.9 32.3 36.0 0.3 1.1 26.7 3.1 39.4 13.0 9.0 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease mutation, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 106.0;lymphoid tissue: 70.0;tongue: 86.8" "Cell type enhanced" "Detected in some" 17 "Alveolar cells type 1: 11.9;Club cells: 6.8;Distal tubular cells: 24.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 78.3" "Region enriched" "Detected in single" 11 "cerebellum: 3.0" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 13.1;HaCaT: 18.0;HeLa: 11.8;MCF7: 12.9;SK-BR-3: 16.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB015159, HPA040171" Enhanced Approved "Vesicles,Plasma membrane" NA NA 430000 "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869" "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 2.9 0.2 0.2 0.4 0.2 0.2 0.7 3.0 0.3 10.1 1.0 0.2 0.2 0.3 0.5 2.0 106.0 1.3 0.2 0.6 0.2 0.0 0.6 0.3 0.9 0.4 0.2 0.2 0.7 1.3 0.2 0.2 0.9 0.2 0.5 0.3 0.4 12.8 1.4 0.7 9.3 0.3 0.2 0.2 0.4 0.2 0.4 0.2 0.5 0.4 86.8 70.0 0.4 17.2 0.4 0.5 0.0 0.5 0.0 1.1 0.2 0.8 1.5 0.8 0.7 0.0 0.6 13.1 0.3 0.2 0.7 1.3 0.9 1.3 0.8 1.7 1.0 0.2 18.0 2.1 1.5 0.5 1.4 2.5 1.0 11.8 4.1 0.6 0.6 1.1 1.1 7.1 0.4 1.5 0.4 0.5 2.5 0.7 0.8 0.5 12.9 0.5 1.4 0.2 0.8 1.6 0.8 0.1 0.8 0.5 1.5 0.9 1.2 0.2 16.0 0.0 1.1 1.1 0.8 0.6 0.8 3.8 1.5 0.6 1.1 1.2 0.2 0.3 1.5 0.9 0.0 0.5 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.2 0.2 3.0 0.2 0.2 0.0 0.2 0.2 0.2 0.2 11.9 1.4 0.0 4.2 0.2 0.8 0.8 0.0 0.0 6.8 0.0 0.0 1.1 24.9 1.9 0.1 0.0 0.0 0.0 0.8 0.6 0.6 3.1 4.6 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.4 0.1 0.6 0.0 0.3 0.0 0.8 1.6 1.0 0.0 0.0 4.6 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127387-38166578 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 187.6;placenta: 212.7" "Cell type enhanced" "Detected in many" 7 "Cytotrophoblasts: 276.1;Ito cells: 326.6;Pancreatic endocrine cells: 240.4;Syncytiotrophoblasts: 312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "intermediate monocyte: 2.5;memory B-cell: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 23 "B-cells: 1.9;dendritic cells: 2.4;monocytes: 2.5" "Group enriched" "Detected in many" 4 "CAPAN-2: 155.5;EFO-21: 52.3;hTERT-RPE1: 102.6;HUVEC TERT2: 70.7;TIME: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" Yes No 1700000 Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 33.3 9.5 6.0 18.3 8.1 1.0 7.7 4.3 7.5 94.3 12.6 4.0 4.7 8.4 54.6 21.7 15.8 58.7 62.8 77.1 7.5 3.4 25.3 187.6 61.2 16.4 6.9 3.0 18.7 5.0 5.2 25.6 212.7 8.5 33.6 6.3 57.4 1.9 17.1 19.3 0.7 12.8 43.9 5.7 20.4 13.6 7.4 6.4 0.8 17.0 3.4 3.1 38.2 21.6 1.9 2.4 0.0 2.5 0.0 0.0 0.2 6.3 4.7 0.0 0.1 4.9 0.5 2.4 9.6 4.6 0.0 0.1 7.8 155.5 0.0 52.3 0.1 11.1 0.1 0.0 22.5 0.3 0.0 0.0 1.0 0.2 3.4 20.3 0.0 0.0 0.5 0.0 4.1 0.0 102.6 70.7 0.0 2.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.9 0.0 0.0 0.1 22.6 0.0 0.8 3.3 0.2 0.0 92.1 0.1 5.9 0.7 4.5 0.0 0.0 0.0 6.3 0.0 1.8 0.0 0.2 0.0 0.0 2.5 0.0 1.9 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 8.1 4.3 7.5 7.5 3.4 6.9 3.0 8.5 6.4 8.9 28.9 15.2 9.8 0.5 0.0 156.9 48.4 16.0 27.3 14.0 2.0 276.1 3.3 184.1 2.3 166.8 4.2 93.5 124.7 21.8 45.8 45.4 2.3 137.1 49.2 0.0 0.0 326.6 22.9 3.5 1.1 11.4 0.0 10.8 0.0 0.4 240.4 0.0 5.6 19.0 0.5 0.0 65.7 0.5 4.9 0.0 312.9 1.3 0.4 12.3 TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341078 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 195.0;lymphoid tissue: 152.6;tongue: 206.5" "Cell type enriched" "Detected in some" 6 "Intestinal endocrine cells: 44.4" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 205 "neutrophil: 20.4" "Lineage enriched" "Detected in single" 205 "granulocytes: 20.4" "Cell line enriched" "Detected in some" 6 "EFO-21: 11.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA004728 Enhanced NA NA 14000000 "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.1 0.1 195.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 24.5 0.0 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 206.5 152.6 0.0 2.8 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.4 0.0 0.3 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 44.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 7.2 0.0 0.0 0.0 0.0 TGM4 TGP ENSG00000163810 "Transglutaminase 4" P49221 3 44874608-44914990 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "prostate: 107.8" "Cell type enriched" "Detected in some" 37 "Glandular cells: 201.3" "Cancer enriched" "Detected in single" 312 "prostate cancer: 75.4" "Region enriched" "Detected in single" 254 "cerebral cortex: 25.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.7;hTERT-HME1: 2.6;NB-4: 5.2;RPMI-8226: 3.7;SH-SY5Y: 2.9" "Not detected" "Not detected" "CAB033571, HPA073290" Enhanced NA NA "CAB033571: AB_2287329, HPA073290: " "unprognostic (4.40e-2)" "unprognostic (4.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.17e-3)" "unprognostic (2.84e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.41e-2)" "unprognostic (1.65e-1)" "unprognostic (8.56e-3)" "unprognostic (5.08e-2)" "unprognostic (1.44e-8)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.68e-1)" "unprognostic (6.41e-2)" 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 25.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.1 2.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.0 0.7 0.7 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.5 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.2 0.2 201.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.8 0.0 0.0 2.6 TGM5 TGX ENSG00000104055 "Transglutaminase 5" O43548 15 43232595-43266857 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 9.7;lymphoid tissue: 10.4;skin 1: 24.3;tongue: 13.1" "Cell type enhanced" "Detected in some" 21 "Early spermatids: 3.1;Late spermatids: 2.6;Suprabasal keratinocytes: 5.8;Urothelial cells: 12.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEL: 20.2" "Region enriched" "Detected in single" 11 "cerebellum: 2.9" "Not detected" "Not detected" NA NA "unprognostic (3.17e-2)" "unprognostic (1.03e-2)" "unprognostic (5.92e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-15)" "unprognostic (1.94e-1)" "unprognostic (3.14e-1)" "unprognostic (7.22e-3)" "unprognostic (5.71e-2)" 0.3 0.0 0.1 0.1 0.1 0.2 2.1 0.1 0.1 2.6 0.1 0.1 0.1 0.0 0.7 0.1 9.7 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.6 0.0 0.1 2.8 3.4 0.1 24.3 0.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 13.1 10.4 0.8 4.7 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.4 0.0 0.7 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 2.3 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.8 1.6 0.0 0.0 12.6 TGM6 "dJ734P14.3, SCA35, TGM3L, TGY" ENSG00000166948 "Transglutaminase 6" O95932 20 2380908-2432753 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "lymphoid tissue: 5.7;skin 1: 3.3;tongue: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "SCLC-21H: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 1.8" HPA059196 Uncertain NA NA "HPA059196: AB_2683943" "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.2 5.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276280-43302255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.9;testis: 2.9" "Cell type enriched" "Detected in some" 5 "Early spermatids: 60.4" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 78 "EFO-21: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 5.9 0.0 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 2.8 TGS1 "NCOA6IP, PIMT" ENSG00000137574 "Trimethylguanosine synthase 1" Q96RS0 8 55773142-55825448 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025024, HPA029824" Supported Supported Cytosol NA NA Cytosol "HPA025024: AB_1854330, HPA029824: AB_2673212" "unprognostic (4.13e-2)" "unprognostic (7.46e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.94e-2)" "unprognostic (9.32e-2)" "unprognostic (3.15e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (8.62e-2)" "unprognostic (7.23e-2)" "unprognostic (3.42e-1)" "unprognostic (2.85e-2)" 12.1 10.0 7.2 18.2 9.1 13.3 12.6 18.1 10.2 11.6 14.1 7.2 18.2 7.6 14.3 16.0 13.5 14.1 9.4 8.5 8.8 6.7 12.6 8.8 10.7 18.8 5.3 6.9 14.8 9.6 12.3 13.8 10.2 7.4 11.9 10.1 7.1 11.6 20.0 19.6 14.1 16.8 11.5 6.3 17.7 10.5 10.8 8.0 29.7 11.6 13.2 18.3 14.5 14.5 10.4 10.1 10.0 7.6 6.3 13.1 4.8 9.3 7.0 8.4 9.3 7.3 7.3 8.7 8.8 9.0 9.4 9.6 6.5 9.1 21.1 6.1 5.8 7.1 9.0 17.6 11.2 11.9 11.7 6.7 22.6 7.8 3.6 10.4 12.6 7.8 7.2 7.6 9.0 18.4 4.3 7.2 12.4 18.4 8.3 7.6 7.1 28.3 8.2 30.5 13.9 2.8 20.2 6.0 6.7 8.6 9.4 8.5 11.7 11.2 6.8 10.0 9.4 9.3 7.7 7.0 6.9 8.8 8.2 7.9 7.3 4.8 26.7 6.8 9.9 8.8 10.0 5.5 8.8 11.6 6.3 13.1 9.8 11.6 11.2 5.5 10.4 11.9 12.4 6.3 6.3 7.6 10.1 9.2 4.8 7.2 9.1 18.1 10.2 8.8 6.7 5.3 6.9 7.4 8.0 44.7 29.1 31.2 30.3 32.7 29.5 10.9 17.8 33.5 53.4 48.8 21.6 24.4 3.3 15.9 2.8 25.1 8.9 23.3 21.8 24.3 18.5 18.5 48.5 13.4 17.7 20.6 10.3 20.9 16.7 3.1 27.3 18.6 6.8 17.2 20.3 28.3 19.2 10.5 21.5 14.2 27.6 25.8 18.1 52.9 61.5 22.8 18.8 30.5 18.9 23.8 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785460-2815807 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Enterocytes: 167.6;Paneth cells: 149.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol NA NA 1400000 Cytosol "CAB025497: , HPA035262: AB_2674541" "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 8.2 9.4 19.1 12.3 19.8 18.4 6.2 21.7 26.1 5.2 11.8 14.1 5.8 24.6 7.5 8.4 11.0 8.4 6.7 11.6 18.5 15.4 7.1 30.4 6.2 11.9 14.1 15.2 11.1 7.8 7.0 12.7 22.3 13.1 18.1 8.2 11.9 13.7 6.8 29.1 11.9 20.0 7.1 10.7 9.8 7.8 27.3 10.9 17.0 7.5 11.5 11.3 5.8 6.8 7.5 9.8 8.0 7.5 3.9 9.5 3.2 29.4 21.9 8.6 18.3 4.4 4.3 30.5 18.4 6.8 18.3 14.8 25.7 9.4 26.6 9.0 7.1 12.8 24.0 12.7 15.1 7.7 0.1 26.6 9.4 24.1 30.4 4.7 18.1 14.7 4.8 5.4 15.2 6.8 5.2 10.4 18.0 21.8 13.0 7.7 22.8 20.1 34.0 25.2 8.8 30.2 16.7 11.4 25.1 7.6 17.1 23.3 18.5 16.1 14.5 8.9 4.6 14.0 17.6 11.7 14.1 12.1 30.0 31.1 22.8 19.1 17.9 15.7 30.4 16.7 8.0 3.5 1.6 5.5 3.9 4.5 5.6 4.0 7.4 4.9 7.5 5.1 4.3 1.7 3.9 7.5 9.8 9.5 3.2 19.1 19.8 21.7 26.1 18.5 15.4 14.1 15.2 13.1 10.9 3.0 11.7 12.3 8.7 6.1 20.3 7.3 10.2 5.3 7.9 10.4 33.4 20.9 8.3 17.0 11.4 5.7 167.6 0.0 12.9 46.8 8.4 12.6 5.7 79.1 19.9 6.4 39.2 6.2 9.5 18.4 10.6 7.0 3.3 11.8 46.9 12.9 15.9 149.7 5.6 9.1 29.7 12.9 9.2 47.9 19.4 5.1 28.3 6.5 38.5 6.4 TIPARP "DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Basal keratinocytes: 174.1;Early spermatids: 204.3;Urothelial cells: 186.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "basophil: 24.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules NA NA Microtubules "HPA036796: AB_10672268" "prognostic favorable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 31.6 29.8 10.9 11.1 24.7 31.8 19.9 7.1 16.3 16.2 12.7 14.2 18.8 6.8 18.3 20.7 27.2 27.8 18.8 26.5 16.0 9.4 14.2 21.3 20.2 15.2 16.2 6.2 37.0 14.5 73.8 11.4 6.1 30.9 13.6 7.5 10.0 8.2 36.0 17.4 26.2 22.1 21.6 37.4 8.4 11.3 23.1 12.5 8.4 10.8 19.1 13.8 18.7 16.7 3.7 3.3 24.1 5.4 7.0 6.0 2.2 12.5 8.8 3.0 2.5 11.1 8.2 2.4 21.0 17.0 10.7 14.9 5.0 26.2 3.7 6.8 23.8 14.3 13.1 7.6 50.4 15.9 7.9 5.6 6.3 9.2 3.4 4.7 2.1 11.7 6.6 31.6 10.9 26.3 29.0 9.7 2.8 4.9 15.1 37.1 2.4 1.8 2.8 3.4 15.8 7.4 3.1 6.8 12.9 11.3 6.0 9.2 2.3 16.5 5.1 3.5 7.2 7.9 3.7 21.0 4.6 1.5 8.7 7.5 16.9 3.0 3.3 7.9 3.3 15.5 24.1 3.5 4.7 4.2 2.2 6.0 1.9 4.2 5.6 2.3 3.7 2.6 3.5 10.7 7.0 5.4 3.3 4.7 2.2 10.9 24.7 7.1 16.3 16.0 9.4 16.2 6.2 30.9 12.5 80.4 77.0 6.1 84.9 174.1 4.4 21.3 30.6 46.8 81.9 7.0 37.3 3.3 18.3 29.3 204.3 26.0 33.2 0.0 20.7 6.8 35.1 72.6 116.2 17.0 17.1 20.6 52.3 13.5 16.1 11.0 18.1 36.2 35.4 20.8 21.8 7.8 28.1 28.1 18.0 8.2 9.4 12.9 57.7 61.8 20.2 106.1 6.3 34.5 12.3 186.7 TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA016043: AB_1858027" "unprognostic (2.13e-2)" "unprognostic (3.87e-1)" "unprognostic (7.36e-2)" "unprognostic (6.00e-3)" "unprognostic (2.00e-1)" "unprognostic (6.78e-2)" "unprognostic (2.47e-2)" "unprognostic (7.60e-2)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.53e-1)" 13.8 20.1 22.0 32.9 21.0 14.4 26.2 18.3 23.2 19.6 20.2 8.4 22.3 13.7 16.1 16.1 14.1 14.4 16.2 12.7 20.6 19.3 19.5 21.4 22.1 33.7 21.7 20.8 21.5 19.8 37.8 21.0 36.0 18.3 18.0 18.2 10.8 16.4 30.3 18.6 15.4 18.9 20.5 18.7 26.0 19.9 24.2 12.2 28.0 25.7 11.1 21.7 21.9 19.1 10.5 5.3 11.3 5.5 9.5 12.3 6.6 8.6 8.5 12.3 9.6 8.8 8.8 13.6 12.1 17.6 12.2 10.2 11.7 14.2 18.0 9.9 18.1 13.2 7.4 15.6 13.5 13.4 21.4 7.8 20.8 10.6 15.1 9.5 26.3 10.5 9.6 13.8 24.2 16.0 13.0 13.3 11.6 21.3 15.4 7.3 10.8 22.1 8.4 11.3 8.4 4.8 16.7 14.9 18.6 10.0 16.7 14.0 10.9 13.1 9.3 8.9 8.7 7.6 9.2 18.1 10.9 13.4 7.1 9.4 12.9 21.7 32.7 13.5 10.9 10.9 11.3 3.9 6.5 6.6 3.0 9.1 10.5 10.7 7.2 3.5 10.5 12.3 8.1 5.0 9.5 5.5 5.3 10.0 6.6 22.0 21.0 18.3 23.2 20.6 19.3 21.7 20.8 18.3 12.2 47.6 23.8 55.6 30.2 36.7 31.7 26.5 28.1 33.5 29.6 48.8 56.9 70.8 74.6 24.8 57.8 27.4 38.0 23.3 28.2 44.9 25.5 42.8 26.5 30.0 23.9 42.9 23.0 12.3 25.7 21.5 40.0 26.9 35.4 15.4 31.6 25.5 28.4 34.8 42.1 38.3 72.6 0.0 28.8 29.9 22.6 34.3 146.2 48.0 28.0 31.4 TLK2 "MGC44450, PKU-ALPHA" ENSG00000146872 "Tousled like kinase 2" Q86UE8 17 62458658-62615481 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.9" "Cell type enhanced" "Detected in all" 5 "Late spermatids: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" "unprognostic (7.06e-2)" "unprognostic (1.48e-2)" "unprognostic (9.53e-3)" "unprognostic (6.57e-2)" "prognostic unfavorable (9.40e-4)" "unprognostic (4.53e-2)" "unprognostic (5.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.82e-2)" "unprognostic (4.78e-2)" "unprognostic (5.32e-2)" "unprognostic (9.79e-2)" "unprognostic (4.32e-2)" "unprognostic (4.88e-1)" "unprognostic (7.30e-2)" 7.4 6.4 8.3 7.3 7.2 12.0 12.5 7.8 14.0 5.8 7.8 4.0 3.1 7.4 9.0 3.1 9.0 6.2 9.9 17.8 7.7 7.4 5.7 5.0 6.9 8.7 7.7 7.3 8.5 8.9 5.6 6.9 9.0 10.4 6.6 5.3 7.5 8.6 8.7 11.7 8.7 10.1 6.5 8.6 8.9 6.7 47.9 5.7 4.1 11.7 3.1 10.0 8.5 7.2 4.6 3.6 8.6 2.8 6.6 4.9 1.5 15.8 14.6 25.2 26.6 8.2 10.7 14.7 17.5 13.6 20.7 19.0 15.1 14.2 31.0 9.0 11.4 18.3 10.8 17.7 7.5 19.8 16.4 14.1 21.1 13.7 15.2 14.7 22.2 13.4 9.2 10.2 13.9 16.9 12.7 10.2 17.7 20.8 14.1 11.1 34.5 31.6 7.9 16.0 9.3 12.2 21.7 33.2 9.8 9.8 15.9 27.2 36.7 14.9 10.2 22.4 22.1 17.3 20.0 13.8 29.1 27.7 13.1 19.7 16.4 20.4 28.4 12.0 11.4 15.2 3.7 2.8 8.6 2.5 2.2 2.6 4.5 4.4 3.1 2.5 4.6 3.5 4.6 5.5 6.6 2.4 3.6 4.9 1.5 8.3 7.2 7.8 14.0 7.7 7.4 7.7 7.3 10.4 5.7 29.8 22.4 16.6 13.3 20.1 58.1 26.4 12.7 38.8 12.5 14.0 78.5 9.5 10.0 8.7 90.3 13.1 14.6 23.3 8.6 9.8 15.0 18.6 19.7 8.3 10.8 27.0 17.2 11.1 14.2 128.6 19.5 18.0 16.9 10.0 14.2 23.8 12.6 23.0 16.6 6.3 82.2 6.5 16.0 73.9 28.9 19.2 12.7 14.1 15.1 20.0 TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33096801 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 5 "Alveolar cells type 2: 2.2;Rod photoreceptor cells: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 5.5" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "BEWO: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Nucleoplasm, Mitochondria" "HPA027019: AB_1848942" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (5.03e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-3)" "unprognostic (8.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-3)" "unprognostic (9.58e-2)" "unprognostic (1.60e-7)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.13e-1)" "unprognostic (4.33e-2)" 6.3 5.4 3.7 6.8 5.2 20.3 6.8 5.3 7.4 4.5 6.9 4.1 7.4 6.4 6.5 12.0 7.0 5.4 9.9 4.4 3.6 3.7 13.9 13.1 9.3 9.6 3.5 3.0 5.7 9.7 12.1 5.2 8.4 4.9 4.6 6.5 9.0 7.7 6.5 3.8 10.3 11.0 4.6 3.8 7.2 6.8 3.2 2.3 2.4 9.5 2.2 7.2 5.3 5.0 0.8 2.2 4.2 5.5 0.1 1.4 0.9 1.3 1.7 1.0 1.6 1.2 1.0 25.5 0.6 0.9 1.5 0.9 2.5 3.5 0.7 1.1 1.6 0.8 1.4 1.6 1.4 2.5 3.8 0.6 3.1 1.7 1.9 0.8 2.6 4.5 1.1 1.2 1.9 1.3 0.7 1.8 1.6 2.3 2.7 1.1 1.2 1.1 1.2 1.0 0.3 1.0 1.3 0.5 1.7 1.4 1.7 0.2 0.6 0.8 2.4 0.6 1.3 1.3 3.8 2.5 2.3 2.9 1.2 2.4 2.2 1.4 0.4 2.9 2.0 1.5 0.0 2.3 0.7 0.4 5.5 1.4 0.8 0.5 0.1 2.2 0.3 0.0 0.0 4.2 0.1 2.3 0.4 0.5 0.9 3.7 5.2 5.3 7.4 3.6 3.7 3.5 3.0 4.9 2.3 0.0 2.2 0.0 0.0 0.7 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.1 1.3 0.0 0.7 1.2 0.3 0.2 0.0 0.2 0.8 1.6 0.0 0.6 1.2 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.4 0.9 0.4 0.3 2.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.6 0.1 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715298 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.8 16.8 14.7 22.8 31.3 12.2 20.5 28.0 34.2 16.4 15.4 14.0 16.0 17.8 22.1 21.7 16.9 18.3 16.8 20.2 17.1 18.2 19.2 19.9 23.3 25.6 14.2 18.7 16.0 16.3 20.4 19.3 19.6 26.8 18.7 16.9 18.2 14.6 16.3 14.1 16.5 21.1 21.1 16.7 26.3 15.2 11.1 11.1 29.6 19.2 13.4 22.1 19.9 14.8 4.9 9.6 3.4 6.9 7.6 8.7 4.1 3.4 5.5 10.7 8.3 22.1 23.7 7.9 27.2 29.1 19.8 22.2 2.6 10.2 9.8 5.4 39.5 8.4 13.0 7.0 13.6 30.5 9.3 6.3 9.0 8.7 4.5 23.5 19.0 14.9 18.8 8.8 21.4 19.4 20.3 25.1 8.6 5.7 13.7 23.5 2.1 10.2 6.0 4.5 2.8 9.0 9.5 21.2 11.9 16.8 7.5 10.3 8.0 13.2 8.6 10.0 11.1 5.6 16.3 24.0 35.5 9.7 7.9 19.8 9.2 9.2 9.2 21.5 15.8 25.9 2.6 4.3 3.4 6.1 6.9 8.7 4.9 6.3 5.6 6.9 3.6 7.1 6.9 1.1 7.6 4.7 9.6 6.4 4.1 14.7 31.3 28.0 34.2 17.1 18.2 14.2 18.7 26.8 11.1 26.8 23.8 18.0 14.7 18.0 26.7 19.3 15.3 33.5 17.0 15.7 17.7 12.5 1.7 13.7 2.1 24.0 10.8 0.0 8.8 17.9 26.7 15.3 19.7 22.1 16.4 25.4 17.2 30.1 22.9 2.3 22.5 24.0 23.6 7.2 13.0 24.1 13.2 11.9 15.6 5.7 31.8 38.8 20.6 18.2 26.0 21.2 10.4 19.3 7.6 14.0 TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171061339-171460408 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell type enhanced" "Detected in many" 7 "granulocytes: 79.9;Muller glia cells: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 23 "basophil: 4.4;eosinophil: 10.5;gdT-cell: 4.2;MAIT T-cell: 5.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.7;naive CD4 T-cell: 6.7;naive CD8 T-cell: 3.8;NK-cell: 2.7;T-reg: 5.3" "Group enriched" "Detected in many" 29 "granulocytes: 10.5;NK-cells: 2.7;T-cells: 6.7" "Cell line enhanced" "Detected in many" "AF22: 19.9;HEL: 27.0;HMC-1: 30.8;WM-115: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol NA NA 9100 Nucleoplasm Cytosol "HPA012128: AB_1858226, HPA012297: AB_1858225" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (5.90e-2)" "unprognostic (5.25e-2)" "unprognostic (9.23e-2)" "unprognostic (4.91e-2)" "unprognostic (2.41e-3)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (5.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.34e-3)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (3.97e-2)" 2.2 5.4 29.0 7.4 30.9 4.9 3.6 21.1 26.1 1.9 10.9 12.2 4.1 25.8 4.3 2.1 5.6 4.3 7.1 11.2 30.9 14.8 5.6 4.6 11.3 7.9 11.4 18.3 2.6 5.2 0.7 9.0 3.1 13.6 5.6 9.5 3.5 2.9 7.3 23.2 1.6 25.6 6.0 14.5 5.8 9.2 10.7 21.1 3.7 7.1 2.2 6.9 6.4 2.6 0.2 0.0 10.5 0.1 2.7 6.7 1.1 0.3 0.5 19.9 2.1 0.3 0.0 4.7 4.1 1.2 3.3 2.2 17.8 7.4 0.0 1.5 3.8 3.0 6.1 2.8 1.1 3.6 0.1 4.4 27.0 1.5 0.0 9.5 5.3 30.8 2.9 3.0 1.9 0.4 7.7 19.8 4.5 9.7 0.0 0.5 0.4 1.7 6.8 8.2 14.2 7.7 0.0 5.1 7.1 6.4 0.0 0.9 1.0 2.5 0.2 4.4 2.2 9.0 1.3 0.2 0.0 3.5 9.0 3.0 0.0 0.0 0.0 0.9 6.0 23.0 4.4 0.1 10.5 4.2 0.0 5.2 0.0 5.0 3.7 0.0 0.2 6.7 3.8 0.1 2.7 0.1 0.0 5.3 1.1 29.0 30.9 21.1 22.2 30.9 14.8 11.4 18.3 13.6 21.1 6.0 37.9 0.5 1.4 2.3 9.3 25.7 25.5 2.7 12.5 8.7 13.7 4.7 5.0 9.2 29.5 1.6 26.2 0.0 6.8 1.8 4.4 0.6 79.9 6.8 2.5 0.0 12.7 1.3 5.6 33.0 2.3 3.3 1.7 0.0 9.4 79.4 4.8 16.5 6.0 14.9 27.7 0.0 7.6 2.8 1.0 1.4 2.1 31.2 15.3 2.4 TNKS "PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555914-9782346 "Enzymes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 9.1 13.4 17.8 8.7 19.6 14.6 14.0 26.5 22.3 18.1 8.9 17.0 12.5 8.5 14.9 25.3 7.7 11.9 8.9 9.5 18.6 17.9 9.0 9.1 10.3 12.9 28.7 17.2 19.2 10.2 23.9 20.0 11.0 20.1 11.5 10.0 10.9 9.4 11.7 22.1 15.6 9.8 11.0 21.0 8.7 10.1 26.3 21.8 15.6 13.7 4.4 11.7 10.8 13.6 6.8 3.6 7.4 2.8 2.9 4.8 1.2 6.1 8.1 20.8 12.5 13.2 17.7 7.7 9.5 10.8 7.7 8.8 4.8 4.9 13.2 3.9 9.3 10.4 6.5 11.8 8.9 11.2 3.4 6.1 9.2 7.4 10.8 11.9 4.7 5.7 12.5 10.8 8.0 15.8 12.6 10.4 10.3 8.6 14.1 14.2 4.0 11.9 7.2 13.6 6.7 4.7 9.6 12.9 3.8 9.3 12.5 21.2 15.6 7.4 7.1 13.4 13.2 4.7 7.1 13.9 12.7 7.8 8.6 7.0 4.9 7.9 9.4 13.7 6.7 12.2 4.8 2.3 1.8 4.4 2.2 2.4 4.2 3.5 4.2 2.8 6.8 4.2 4.8 7.4 2.9 2.8 3.6 1.7 1.2 17.8 19.6 26.5 22.3 18.6 17.9 28.7 17.2 20.1 21.8 14.9 9.4 11.0 11.2 10.2 32.0 14.3 17.8 26.8 9.1 8.7 13.7 9.0 1.7 9.8 118.1 10.9 9.0 0.0 7.4 7.7 14.9 11.9 9.3 15.8 6.2 39.7 13.3 20.9 9.4 58.4 15.5 7.3 11.8 1.8 13.5 18.4 11.2 13.1 17.0 6.0 36.2 0.0 9.9 30.7 13.5 13.6 10.3 11.5 11.7 10.2 TNKS2 "PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL" ENSG00000107854 "Tankyrase 2" Q9H2K2 10 91798312-91865276 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036606 Approved Microtubules NA NA Microtubules "HPA036606: AB_10673470" "unprognostic (1.12e-1)" "unprognostic (2.66e-1)" "unprognostic (4.16e-1)" "unprognostic (1.61e-2)" "unprognostic (3.07e-2)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (2.93e-1)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (2.26e-2)" "unprognostic (1.00e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (7.97e-2)" "unprognostic (2.53e-1)" 17.6 16.3 16.7 23.0 18.6 26.9 18.4 27.9 20.0 18.8 13.9 18.3 18.3 11.9 18.9 18.8 24.7 16.7 17.2 12.2 16.6 14.9 14.6 16.8 17.0 22.9 20.3 14.9 26.0 19.3 20.8 26.7 47.5 16.1 16.7 14.3 16.1 21.4 16.0 39.7 23.9 16.5 18.9 18.0 22.8 15.8 9.5 17.9 42.9 24.5 21.0 23.8 18.6 18.9 3.6 5.2 3.8 2.5 3.3 3.5 1.4 14.2 12.1 25.0 21.2 17.7 16.2 27.9 15.3 28.0 18.7 23.0 10.7 11.6 13.4 7.4 19.9 12.6 15.4 15.6 11.8 26.6 13.5 15.1 11.1 11.6 11.9 17.2 21.3 16.6 16.4 15.7 18.9 33.8 28.3 17.5 12.1 8.1 14.9 19.4 7.6 18.3 14.6 12.5 6.5 8.1 17.2 15.6 10.1 12.8 15.4 6.5 11.8 15.4 6.8 19.0 21.0 16.5 14.9 18.9 10.1 8.6 13.3 14.5 18.8 15.4 17.5 13.4 16.1 9.0 1.0 2.5 3.8 3.5 2.3 3.0 3.5 3.3 3.2 3.4 3.6 2.8 2.4 2.5 3.3 2.2 5.2 1.7 1.4 16.7 18.6 27.9 20.0 16.6 14.9 20.3 14.9 16.1 17.9 38.7 18.2 20.6 28.6 66.2 37.6 18.2 10.2 37.5 27.3 41.8 45.2 36.2 6.6 14.8 4.0 33.7 12.9 0.0 21.2 46.2 23.5 36.2 2.3 30.5 23.0 39.7 31.8 35.6 54.0 5.9 28.7 29.3 32.1 17.2 20.1 33.3 24.0 11.5 33.2 14.5 30.9 45.3 29.7 16.3 19.4 95.4 84.4 29.7 13.4 52.2 TOPORS "LUN, RP31, TP53BPL" ENSG00000197579 "TOP1 binding arginine/serine rich protein" Q9NS56 9 32540544-32552553 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 33.4" "Cell line enhanced" "Detected in all" "HEL: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060640, HPA065661" Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA060640: AB_2684334, HPA065661: AB_2685527" "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-2)" "unprognostic (9.94e-2)" "prognostic favorable (7.07e-4)" "unprognostic (2.70e-1)" "unprognostic (3.61e-1)" "prognostic favorable (6.64e-6)" "unprognostic (1.22e-1)" "unprognostic (5.95e-2)" "unprognostic (3.13e-1)" "unprognostic (2.92e-1)" 16.0 12.5 12.7 8.5 16.0 22.9 13.7 18.6 15.1 14.0 12.2 9.6 9.5 8.8 12.9 11.4 13.1 10.5 11.7 9.3 15.9 9.6 14.6 17.4 10.6 10.0 20.1 5.2 17.5 13.2 19.6 19.5 17.9 14.8 13.1 10.3 9.2 11.0 10.8 10.9 10.2 16.8 12.3 17.8 12.4 10.7 18.9 15.0 15.5 15.6 9.8 10.5 16.3 16.0 5.2 4.9 33.4 5.9 7.1 7.4 3.4 8.2 7.6 10.5 9.2 12.9 11.7 6.7 10.5 9.9 8.7 10.2 4.7 4.2 13.4 6.1 10.5 7.7 5.5 12.4 11.9 12.3 11.1 6.8 45.2 13.3 5.9 8.0 12.8 12.5 9.4 13.4 12.6 8.9 10.9 10.6 10.2 7.8 7.0 14.2 4.4 11.4 23.6 14.0 6.1 7.8 11.8 9.4 6.0 11.7 8.7 5.2 8.4 10.5 5.7 6.8 12.4 5.8 7.3 11.1 9.6 9.8 5.0 7.7 4.9 7.8 14.5 8.9 7.4 4.3 14.6 4.9 10.0 5.0 4.6 5.4 4.6 5.4 5.8 4.9 5.2 7.4 7.2 33.4 7.1 5.9 4.0 6.3 3.4 12.7 16.0 18.6 15.1 15.9 9.6 20.1 5.2 14.8 15.0 50.6 20.6 26.5 37.9 41.9 48.4 16.8 28.1 18.7 38.7 24.4 35.3 25.9 16.6 21.0 148.7 37.9 22.0 0.0 16.2 14.5 27.8 32.6 40.5 20.2 15.7 52.4 44.0 22.1 16.6 13.0 30.8 27.2 18.6 27.9 18.4 48.5 18.7 22.9 30.8 19.1 38.4 19.4 37.1 51.9 49.7 41.7 42.4 34.1 19.0 41.6 TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689779 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 70.6" "Low region specificity" "Detected in all" "CAB004688, HPA015837" Approved NA NA "CAB004688: AB_426116, HPA015837: AB_1855776" "unprognostic (9.45e-2)" "unprognostic (3.73e-1)" "unprognostic (9.76e-2)" "prognostic unfavorable (6.70e-5)" "unprognostic (4.41e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.16e-3)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.72e-2)" "unprognostic (1.25e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.74e-2)" 11.2 14.5 12.7 12.6 15.3 9.6 16.8 8.1 20.3 14.1 11.7 13.7 5.3 8.8 14.8 8.9 16.9 12.2 12.6 9.9 12.1 11.3 12.7 13.6 10.6 18.2 13.1 12.8 15.3 10.1 11.8 15.7 14.9 12.1 15.5 11.4 12.6 13.8 12.2 12.4 16.8 11.2 12.7 10.6 13.2 13.3 26.4 11.8 21.9 16.6 13.1 21.1 14.3 12.7 14.7 19.1 21.7 12.4 16.2 18.5 12.2 4.0 2.8 5.9 5.2 6.3 5.2 5.4 5.7 5.3 7.5 5.5 7.9 2.6 9.7 8.6 4.7 6.8 6.3 7.5 6.5 6.6 2.4 3.8 9.8 2.8 7.0 8.3 6.3 70.6 6.9 8.0 5.2 5.2 3.5 4.9 4.1 6.6 4.3 6.4 6.0 9.5 10.5 4.8 5.8 9.4 5.6 5.3 5.7 5.0 4.4 7.1 3.7 6.9 13.9 27.6 3.2 5.0 7.0 5.0 8.8 5.1 5.7 6.3 4.7 5.8 7.7 5.1 4.8 4.1 21.7 12.4 20.6 13.7 11.5 15.8 14.7 14.8 15.6 12.6 14.2 16.4 14.0 2.0 16.2 10.2 19.1 18.5 12.2 12.7 15.3 8.1 20.3 12.1 11.3 13.1 12.8 12.1 11.8 8.9 12.5 16.4 45.5 45.1 8.7 5.7 12.7 5.3 10.3 8.7 11.8 36.5 23.2 24.6 176.8 13.1 10.9 0.0 20.7 62.1 26.2 45.0 23.0 12.1 23.0 14.3 12.6 12.3 13.1 26.3 20.4 12.4 35.4 20.8 14.8 8.0 29.4 3.5 15.2 25.4 9.8 6.5 23.7 35.2 15.3 54.1 74.1 17.5 12.3 49.2 TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155074 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 48.2" "Cell type enhanced" "Detected in many" 8 "Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019851, HPA062364" Enhanced NA NA "HPA019851: AB_1858213, HPA062364: " "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favorable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" 5.3 13.2 11.5 6.6 10.2 4.9 5.6 13.1 14.3 4.6 18.2 4.1 6.2 18.4 6.5 10.1 8.9 4.1 7.6 6.5 9.0 8.0 40.2 36.2 6.5 6.2 9.3 7.5 3.8 9.4 12.9 11.6 3.3 8.5 6.2 19.4 6.9 12.9 7.2 7.0 5.7 29.4 6.2 7.2 9.4 6.6 4.1 7.5 5.4 48.2 6.3 5.3 6.4 5.6 1.6 16.9 3.7 23.8 5.4 8.3 8.3 11.9 3.6 4.1 10.0 6.7 13.1 10.0 13.9 15.5 11.9 18.6 8.4 3.0 1.5 10.4 18.3 9.2 6.0 5.7 10.0 19.9 7.9 8.2 9.9 6.2 12.3 7.4 4.5 8.9 7.5 10.8 13.3 8.5 7.8 16.5 6.8 19.5 2.9 8.6 5.5 4.6 6.2 6.7 16.6 10.5 5.8 10.0 6.7 13.8 12.3 6.6 5.1 9.1 16.2 17.8 10.6 11.7 4.5 7.0 27.4 5.3 14.3 19.7 4.1 18.5 3.9 9.8 6.2 27.4 3.4 12.0 3.7 6.5 23.8 8.3 1.5 5.3 6.2 16.9 1.6 4.8 6.5 1.2 5.4 19.6 3.7 8.2 8.3 11.5 10.2 13.1 14.3 9.0 8.0 9.3 7.5 8.5 7.5 14.9 13.3 18.0 32.1 37.9 15.1 15.4 22.9 4.0 6.8 33.2 21.6 17.3 97.8 34.1 1.2 11.7 80.0 0.0 32.7 21.7 11.7 34.2 23.0 79.7 40.7 6.4 23.1 12.3 34.5 1.5 3.7 56.7 23.6 19.8 31.8 22.9 51.4 78.6 9.6 230.3 16.8 0.0 14.7 0.4 8.1 30.2 14.6 23.5 36.6 71.2 TPP1 "CLN2, SCAR7" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612763-6619485 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease mutation, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Hofbauer cells: 223.6;Kupffer cells: 312.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 13000000 "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 37.4 64.6 32.2 28.8 36.2 43.0 23.1 15.1 33.3 24.0 26.8 41.7 13.2 28.0 32.0 22.3 20.3 18.0 26.9 25.6 24.5 25.1 36.0 45.1 35.9 42.3 31.0 29.3 22.0 14.8 35.1 30.0 56.4 25.4 19.4 28.2 43.4 18.4 29.1 15.4 15.5 31.4 42.4 32.8 69.0 19.8 17.9 24.7 21.7 24.0 9.1 26.9 25.6 29.4 9.4 43.5 12.8 38.9 7.0 15.3 26.2 4.8 9.8 4.9 9.3 57.7 31.9 3.8 9.5 45.1 7.4 12.9 4.0 20.7 6.9 6.3 24.0 45.7 14.5 9.7 13.3 11.2 6.9 5.6 5.6 5.1 10.9 43.6 8.1 34.2 47.8 21.7 8.6 19.2 49.8 31.5 6.5 10.7 21.0 21.6 6.0 2.5 10.0 3.5 11.4 11.8 6.3 4.1 13.6 13.1 7.6 0.6 3.8 10.2 7.6 17.8 16.9 5.0 15.5 36.0 21.4 6.1 19.2 3.4 17.8 17.4 2.4 27.1 19.0 11.2 12.8 37.7 8.9 10.7 38.9 8.7 9.4 8.5 11.0 43.5 8.5 5.8 7.6 6.9 7.0 26.4 24.2 15.3 26.2 32.2 36.2 15.1 33.3 24.5 25.1 31.0 29.3 25.4 24.7 23.8 31.2 61.7 25.6 21.1 22.8 35.0 58.6 10.7 23.9 15.7 11.8 31.4 5.0 32.3 10.2 39.0 51.3 23.3 11.7 36.7 29.8 25.6 62.2 63.8 223.6 14.3 16.0 90.9 312.0 7.8 25.0 115.7 86.0 64.1 29.1 42.4 18.5 39.0 24.8 46.1 22.8 6.5 22.7 0.5 1.1 17.6 73.6 44.8 28.0 23.0 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240696-1242554 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 24 "granulocytes: 5492.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 308 "basophil: 30.8" "Lineage enriched" "Detected in single" 308 "granulocytes: 30.8" "Cell line enriched" "Detected in some" 173 "HMC-1: 301.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 22.4 0.2 1.6 5.8 1.6 0.0 10.6 1.6 1.6 13.9 17.1 1.6 1.6 17.7 18.7 10.4 15.2 6.1 33.1 4.7 1.6 0.0 4.4 2.8 29.2 16.8 1.6 1.6 2.9 4.5 0.0 1.6 1.9 1.6 24.1 10.0 5.1 14.6 6.3 3.6 29.9 31.0 15.0 1.6 1.6 24.5 5.1 1.6 3.1 3.7 3.8 6.9 21.6 16.0 0.0 0.0 30.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 301.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.6 1.6 1.6 1.6 0.0 1.6 1.6 1.6 1.6 23.8 231.9 0.0 1.4 16.6 0.0 0.2 0.0 9.4 14.8 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 17.1 2.5 5492.7 0.0 5.5 0.0 0.0 0.0 0.3 0.0 0.0 9.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.1 8.7 0.2 1.0 0.0 5.6 TPSB2 ENSG00000197253 "Tryptase beta 2 (gene/pseudogene)" P20231 16 1227272-1230184 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.2" "Cell type enriched" "Detected in some" 18 "granulocytes: 8345.3" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 84 "basophil: 8.4" "Lineage enriched" "Detected in single" 84 "granulocytes: 8.4" "Cell line enriched" "Detected in some" 8 "HMC-1: 83.3" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 7500000 "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 1.8 0.0 0.9 1.9 0.9 0.0 4.1 0.9 0.9 8.8 5.3 0.9 0.9 4.9 2.9 0.9 7.7 0.1 16.2 0.9 0.9 0.9 0.9 12.3 2.4 0.9 0.9 0.9 1.3 0.0 0.9 0.9 0.9 2.7 2.3 0.9 6.2 1.2 0.9 3.4 9.7 4.4 0.9 0.9 13.6 0.9 0.9 0.9 0.9 0.9 0.9 4.2 0.9 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.1 83.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.7 468.0 0.0 1.9 0.0 0.0 1.3 0.0 6.7 30.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.9 8345.3 0.0 4.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 4.6 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1258998 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 17 "granulocytes: 189.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "basophil: 6.4" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.4" "Group enriched" "Detected in some" 48 "HEL: 18.7;HMC-1: 28.6" "CAB002215, CAB032871, HPA040182, HPA049554" Supported "Intracellular and membrane" NA NA "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: AB_2676875, HPA049554: AB_2680815" "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 6.6 0.1 0.6 3.8 0.6 0.8 3.7 0.6 0.8 3.2 5.6 0.6 0.6 2.7 7.5 3.3 7.6 2.3 13.0 2.0 0.6 0.0 1.3 2.3 17.0 13.7 0.6 0.6 0.6 0.9 0.1 0.6 0.9 0.6 4.3 0.4 3.1 3.6 0.7 1.6 7.8 9.3 4.7 0.6 0.6 15.7 3.5 0.6 1.6 1.1 2.8 2.6 8.9 6.6 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.1 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.8 0.6 0.0 0.6 0.6 0.6 0.6 3.0 11.4 0.0 0.0 0.3 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 189.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 16.0 18.2 18.3 22.3 20.6 28.5 39.1 28.7 25.6 22.1 29.4 9.1 21.1 37.3 20.4 18.3 32.9 21.9 36.9 21.0 18.3 14.8 21.3 47.3 18.3 40.9 13.4 14.7 19.3 41.6 17.7 20.3 19.5 12.8 16.2 16.9 13.0 24.4 23.1 25.5 32.2 37.8 28.8 14.1 21.4 25.1 13.2 10.6 26.1 20.3 30.9 21.9 21.9 28.9 6.7 12.3 7.7 13.9 3.0 7.1 5.2 20.7 26.6 15.2 27.2 15.8 29.8 17.9 16.0 20.2 18.9 17.1 32.3 26.8 13.3 19.0 20.4 12.1 24.4 14.2 28.4 7.2 21.0 18.2 19.0 35.4 24.7 20.9 20.2 27.6 29.5 23.8 18.2 23.9 15.6 36.5 26.4 20.3 18.0 18.0 47.5 20.7 23.5 29.9 28.7 13.0 38.7 25.3 26.7 15.2 11.2 30.7 25.5 13.4 25.8 17.5 8.3 29.3 24.9 27.5 23.0 32.4 21.4 17.4 26.1 19.3 17.6 13.1 13.1 17.8 3.7 10.0 7.7 5.4 13.9 5.0 6.7 5.3 5.7 12.3 4.9 3.8 4.5 6.9 3.0 9.4 6.0 7.1 5.2 18.3 20.6 28.7 25.6 18.3 14.8 13.4 14.7 12.8 10.6 0.0 8.6 11.9 15.5 25.5 14.6 3.4 17.8 4.0 4.5 14.0 5.9 20.5 14.9 35.4 3.8 23.9 60.0 0.0 51.6 30.1 20.0 27.8 9.2 26.1 37.6 35.0 32.6 23.4 38.3 9.1 23.0 18.8 10.1 35.1 35.9 10.5 45.1 40.3 20.8 18.9 8.9 6.5 16.0 4.8 21.5 28.4 22.3 12.9 33.8 29.6 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670757 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.3;pancreas: 19.4" "Group enriched" "Detected in some" 4 "Early spermatids: 30.7;Late spermatids: 47.8;Leydig cells: 27.3;Peritubular cells: 12.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Region enhanced" "Detected in many" "cerebellum: 30.3" "Cell type enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BJ: 20.8;BJ hTERT+: 20.2;EFO-21: 10.9;HBF TERT88: 7.4;hTERT-RPE1: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 6200000 "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 6.2 2.2 2.9 1.0 4.7 1.0 7.6 30.3 12.3 10.2 2.4 0.1 2.5 4.8 2.7 1.7 0.9 2.5 2.5 2.2 7.3 2.8 9.9 1.5 3.0 0.6 1.2 5.5 6.5 19.4 0.4 1.6 0.7 1.5 5.5 1.5 1.0 2.4 5.8 0.7 0.8 4.2 1.2 0.9 4.8 1.1 1.7 0.5 0.0 0.5 0.4 1.0 2.8 7.6 0.2 0.0 1.0 0.3 0.3 0.0 0.0 2.4 0.0 0.4 0.0 1.1 0.0 6.7 20.8 20.2 2.0 1.4 0.0 0.0 0.0 10.9 3.0 2.1 0.2 3.8 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.0 0.0 0.0 0.0 6.9 4.6 2.0 0.0 0.0 0.0 0.0 0.4 0.0 4.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 2.9 4.7 30.3 12.3 7.3 2.8 1.2 5.5 1.5 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.0 1.4 0.0 1.8 0.0 0.0 3.3 0.0 30.7 0.0 6.9 0.0 2.2 0.3 0.5 0.2 0.0 1.3 0.2 0.0 0.0 0.0 0.0 47.8 27.3 0.3 0.0 0.0 1.5 0.3 2.1 2.9 12.7 7.4 0.6 0.0 0.4 0.1 0.7 0.0 0.1 0.0 0.7 0.1 TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406840 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA028541: AB_10600833, HPA043879: AB_2678711" "unprognostic (1.73e-1)" "unprognostic (9.73e-3)" "unprognostic (5.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.27e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (7.42e-5)" "unprognostic (1.08e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.89e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" 8.8 9.2 8.9 13.8 16.5 33.2 23.8 45.2 11.5 8.7 11.2 6.4 15.1 10.1 8.7 10.6 13.3 9.4 13.9 6.9 9.2 8.5 7.7 7.1 27.5 18.6 9.0 8.0 9.0 11.9 8.5 7.2 9.4 7.1 10.5 9.7 6.0 14.4 18.2 5.0 12.5 11.8 8.6 6.0 16.5 12.6 9.5 7.8 20.0 9.0 9.7 13.1 9.5 24.3 6.4 6.9 10.0 11.4 9.4 11.8 5.4 13.9 13.2 7.1 9.7 5.4 4.4 33.6 9.1 6.1 10.6 8.5 16.1 12.2 10.5 10.2 6.1 7.0 22.7 8.6 8.8 4.5 11.6 20.6 8.7 12.2 8.6 14.6 10.9 13.2 6.0 14.0 11.0 5.5 5.4 5.2 17.2 19.7 13.5 5.4 9.0 13.2 17.2 18.1 11.8 11.7 13.0 6.4 12.6 6.9 17.1 11.9 21.8 7.6 21.6 12.0 3.0 15.3 18.3 5.8 6.8 9.5 15.7 18.8 13.9 9.2 9.2 8.4 8.8 10.6 6.1 6.9 8.3 9.6 8.2 10.2 5.8 10.7 11.8 6.9 6.4 6.3 8.4 10.0 9.4 11.4 5.5 9.8 5.4 8.9 16.5 45.2 11.5 9.2 8.5 9.0 8.0 7.1 7.8 3.0 7.2 3.9 12.3 14.1 12.6 2.8 7.6 4.0 7.9 1.8 2.0 13.8 14.9 13.0 105.9 8.3 22.7 0.0 9.7 12.0 7.0 15.1 5.7 4.9 10.0 4.8 13.8 6.7 10.0 12.4 8.9 9.7 5.0 25.2 16.1 8.1 14.3 17.3 7.1 6.3 1.7 6.5 9.7 5.5 11.8 16.9 47.9 24.9 13.4 22.9 TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687302-116701300 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease mutation, Limb-girdle muscular dystrophy, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050060 Approved Approved "Intermediate filaments" No No "Intermediate filaments" "HPA050060: AB_2681000" "unprognostic (2.47e-2)" "unprognostic (7.06e-3)" "unprognostic (5.50e-2)" "unprognostic (3.63e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (4.53e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (2.41e-3)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-2)" "unprognostic (5.63e-2)" "unprognostic (6.03e-2)" "unprognostic (7.06e-2)" "unprognostic (2.73e-1)" "unprognostic (6.64e-3)" "unprognostic (9.77e-2)" 9.5 9.1 6.6 5.8 11.5 0.8 8.0 23.2 17.1 12.8 7.9 7.2 6.2 6.7 17.0 8.0 8.8 15.9 8.2 8.9 5.7 7.3 6.2 5.0 6.3 8.4 5.7 9.8 12.6 12.5 12.2 7.7 7.0 9.1 10.3 7.4 10.4 10.9 9.2 23.9 6.6 8.9 12.9 5.3 6.9 6.8 6.5 2.2 9.4 8.4 6.2 8.3 11.1 8.8 6.1 3.5 0.2 2.6 5.6 16.0 4.7 6.5 15.0 8.9 9.8 18.1 13.0 6.7 12.2 13.4 13.9 11.7 10.0 7.2 6.8 5.4 18.7 10.4 14.0 10.8 13.7 12.7 5.9 5.2 3.6 9.7 6.1 9.4 2.4 12.0 11.2 12.4 13.1 7.8 15.4 9.0 7.6 5.0 5.8 16.3 8.4 6.4 0.0 8.1 15.8 9.1 7.6 24.0 4.4 5.7 15.3 8.9 4.5 9.6 6.7 6.9 9.4 18.5 2.4 11.1 13.0 10.4 9.5 9.1 9.5 2.5 10.6 10.8 1.6 12.7 0.0 1.3 0.0 9.3 2.6 7.2 6.1 8.2 7.4 1.8 4.4 8.3 8.4 0.2 5.6 2.1 3.5 16.0 4.7 6.6 11.5 23.2 17.1 5.7 7.3 5.7 9.8 9.1 2.2 6.0 1.1 3.0 5.1 3.8 11.5 6.1 7.6 6.7 5.7 8.7 0.0 6.0 1.7 7.8 2.8 2.4 2.4 0.0 7.0 3.6 6.5 2.8 2.3 3.9 5.8 1.6 4.1 2.5 2.7 1.3 4.9 1.4 1.7 1.0 5.2 4.1 4.9 3.5 11.3 2.2 4.5 0.0 3.6 9.8 11.1 3.1 6.2 4.6 4.9 3.4 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392777-114511160 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Early spermatids: 155.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favorable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 15.2 12.8 16.9 18.4 19.9 27.1 17.1 38.3 21.8 16.9 14.3 11.0 21.9 10.9 19.8 38.3 16.4 15.0 15.6 10.8 18.1 12.5 17.3 15.0 14.3 15.2 12.1 18.0 19.8 15.7 21.8 22.4 27.2 15.2 16.5 13.0 10.7 16.4 19.1 14.3 19.5 14.8 20.2 12.9 14.9 14.1 29.0 16.3 20.5 17.9 9.8 16.6 17.9 28.7 3.4 4.0 12.2 2.8 4.7 4.4 1.0 13.1 7.1 13.4 10.0 5.7 6.0 22.9 6.7 7.2 9.4 10.0 8.0 5.6 14.1 7.0 7.8 6.1 7.6 12.2 7.8 13.0 10.6 7.2 13.6 9.4 9.3 6.3 17.1 11.3 5.7 5.8 11.1 11.4 7.2 7.8 12.0 16.9 10.0 8.9 49.4 17.2 7.3 18.1 5.0 7.2 14.9 20.5 4.6 6.7 20.7 9.3 9.8 12.7 15.4 12.1 9.0 7.0 9.4 8.8 6.5 10.6 15.1 9.4 7.0 6.5 14.7 9.2 10.0 18.5 12.2 1.6 7.4 3.5 1.8 3.1 3.4 3.7 3.7 2.0 2.2 2.9 4.4 4.8 4.7 2.8 4.0 2.0 1.0 16.9 19.9 38.3 21.8 18.1 12.5 12.1 18.0 15.2 16.3 17.9 29.5 19.1 25.9 46.9 71.6 22.0 25.5 10.7 25.0 52.4 92.3 49.7 1.7 18.3 155.1 31.1 23.6 23.3 20.5 27.8 32.1 38.2 36.9 40.5 26.3 25.4 50.1 37.4 44.7 78.9 45.5 39.2 18.6 17.2 31.4 33.5 25.3 32.6 34.6 12.6 58.2 32.3 23.7 54.0 29.6 48.4 73.3 35.5 28.9 48.8 TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663557-5938619 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol NA NA Cytosol "CAB013497: , HPA023420: AB_1856378, HPA023422: AB_1856379" "unprognostic (2.60e-1)" "unprognostic (9.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.48e-3)" "unprognostic (5.82e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (8.54e-3)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (6.12e-2)" 12.5 15.0 3.7 11.6 6.7 3.0 10.7 2.4 5.1 14.2 8.5 4.8 20.1 8.4 16.1 19.9 12.0 11.9 9.9 7.8 5.6 2.9 15.1 16.2 15.2 9.2 6.5 2.9 15.3 24.8 6.1 9.2 12.2 8.8 11.8 8.3 11.8 22.0 12.4 3.0 6.5 13.2 12.0 9.0 19.8 9.5 7.7 6.5 24.9 20.5 7.9 13.3 14.8 12.3 3.9 11.7 13.8 9.8 5.9 5.4 4.6 4.7 7.3 12.5 8.7 13.9 12.8 3.7 10.1 18.8 20.6 27.9 7.4 9.4 3.0 7.9 9.9 16.6 7.8 10.1 14.7 9.3 6.5 2.8 9.1 5.0 5.9 12.3 6.7 9.8 9.7 13.2 6.8 18.1 12.8 31.7 6.6 9.5 6.2 17.3 2.2 5.5 3.1 5.7 7.0 5.1 8.6 2.7 0.8 14.3 9.0 0.3 0.7 7.1 10.3 4.4 12.7 5.3 3.9 23.9 9.7 12.9 1.8 2.4 5.5 3.9 1.2 9.0 4.5 10.0 10.2 9.8 12.9 5.4 9.8 5.3 3.9 4.1 4.3 11.7 3.9 3.4 4.9 13.8 5.9 9.2 9.7 3.3 4.6 3.7 6.7 2.4 5.1 5.6 2.9 6.5 2.9 8.8 6.5 6.0 9.4 12.9 8.1 4.6 0.1 4.8 2.5 2.7 13.6 10.4 0.0 6.5 5.0 10.5 3.2 11.6 5.9 0.0 7.7 8.4 8.9 11.0 0.0 11.1 5.7 0.0 1.2 13.5 11.5 2.3 7.2 7.7 3.3 1.8 8.6 5.7 9.0 3.5 7.1 5.7 0.0 19.4 6.8 5.8 3.6 4.6 6.5 5.7 5.6 8.2 TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051304-26068436 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 271.4" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 236.2" "Cancer enriched" "Detected in some" 10 "melanoma: 31.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "ASC diff: 10.7;SK-MEL-30: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "unprognostic (1.10e-1)" "unprognostic (4.80e-4)" "unprognostic (1.45e-2)" "unprognostic (7.52e-3)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.58e-2)" 3.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 1.2 1.7 0.0 0.6 38.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.5 0.0 3.6 1.0 0.0 271.4 0.6 0.1 0.9 0.1 0.0 0.1 0.1 0.0 0.0 1.7 12.7 0.8 1.2 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.8 0.0 236.2 10.2 0.0 0.0 1.8 0.0 0.4 1.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 9.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.2 0.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.3 4.4 10.7 5.1 23.0 30.2 12.3 11.5 13.7 9.2 10.6 2.8 4.9 2.8 8.6 15.5 22.5 3.8 1.8 5.4 19.1 7.9 2.5 1.5 12.0 3.5 11.9 3.8 4.3 14.1 5.7 32.5 10.4 8.7 8.1 1.9 0.3 1.9 22.3 2.3 0.0 2.6 2.7 1.3 4.0 2.8 6.5 9.5 9.0 5.6 4.9 19.7 9.7 2.5 5.1 14.1 1.5 0.6 18.8 17.8 11.3 12.9 13.5 0.0 0.6 3.6 63.2 2.5 4.2 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 17.9 23.4 9.0 13.2 14.5 29.9 15.7 10.2 16.0 22.7 10.4 13.7 7.6 0.0 18.3 1.9 24.8 13.6 0.0 12.1 17.8 12.4 32.5 17.3 15.3 13.2 27.0 17.3 11.1 12.3 2.4 72.8 16.8 5.0 6.4 21.7 7.1 29.1 16.1 40.3 2.9 3.0 6.5 11.5 2.8 6.4 12.0 6.9 4.6 17.1 20.1 TRIP12 KIAA0045 ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763838-229923239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA036835: AB_2675340, HPA045893: AB_2679486" "unprognostic (1.22e-1)" "unprognostic (4.87e-2)" "unprognostic (2.61e-1)" "unprognostic (3.33e-2)" "unprognostic (6.81e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.37e-3)" "unprognostic (3.49e-3)" "unprognostic (4.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (8.80e-2)" "unprognostic (2.01e-2)" 29.6 28.1 23.6 25.4 26.9 26.9 23.1 20.5 26.2 24.0 23.1 26.2 24.3 14.3 25.3 26.3 30.6 19.9 20.7 35.9 19.0 19.3 26.2 24.9 26.2 26.5 23.1 20.5 24.3 18.8 32.4 33.1 27.2 24.8 25.8 21.3 22.3 25.5 22.0 62.7 23.6 22.0 26.2 23.3 32.5 23.4 77.1 24.0 42.2 28.0 21.5 31.5 26.5 27.4 7.0 9.1 25.8 12.0 9.1 12.7 6.1 24.1 27.3 25.1 21.0 23.9 29.1 23.3 37.4 25.3 27.1 30.2 21.9 19.4 9.4 27.4 33.3 34.8 18.9 36.5 26.6 39.7 38.7 13.3 65.8 22.9 19.3 20.7 49.4 43.0 25.2 20.5 45.0 28.9 21.1 35.3 23.8 48.6 10.2 30.9 18.4 27.6 17.1 19.6 12.3 12.5 25.1 49.5 8.3 20.1 41.6 25.5 18.2 0.5 12.5 25.7 22.8 12.7 30.3 49.0 35.2 25.0 22.8 28.8 17.7 20.2 30.9 26.8 19.5 29.4 18.8 9.9 15.7 9.5 11.3 9.7 7.0 8.8 9.2 9.1 6.8 7.3 7.0 25.8 9.1 12.0 9.0 12.7 6.1 23.6 26.9 20.5 26.2 19.0 19.3 23.1 20.5 24.8 24.0 83.4 49.3 17.2 24.2 27.5 29.6 80.3 38.2 65.6 51.2 29.6 49.1 23.6 13.3 31.9 89.6 47.2 37.6 0.0 38.7 20.9 28.2 43.4 37.1 48.3 30.9 39.7 17.9 58.3 81.5 79.5 32.2 36.5 25.3 26.2 30.2 28.2 45.3 32.3 42.8 26.2 32.5 19.4 30.1 113.9 53.0 31.7 35.5 27.7 25.5 54.5 TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39841022-39883511 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Disease mutation, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024174, HPA027330" Approved Supported Mitochondria NA NA Mitochondria "HPA024174: AB_1858346, HPA027330: " "unprognostic (4.61e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-3)" "prognostic unfavorable (8.80e-4)" "unprognostic (4.00e-2)" "unprognostic (8.55e-2)" "prognostic unfavorable (5.34e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-3)" "unprognostic (3.18e-2)" "unprognostic (3.54e-1)" "unprognostic (6.68e-3)" "prognostic unfavorable (7.08e-8)" "unprognostic (6.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (6.90e-2)" 9.5 10.3 12.9 10.4 19.1 8.0 19.8 25.8 18.4 15.1 13.4 15.9 22.7 11.4 19.3 21.3 19.8 18.4 9.1 15.9 12.5 12.0 14.6 13.2 11.9 14.8 13.9 10.4 16.7 27.7 14.1 26.7 17.6 14.4 21.4 15.8 13.5 15.1 23.9 10.1 22.9 11.7 18.0 9.8 14.0 12.9 17.3 17.9 15.4 19.2 9.4 14.7 17.2 17.5 3.9 13.4 0.9 6.6 2.4 5.2 2.8 14.7 6.8 14.8 15.1 7.4 11.2 22.4 9.8 13.2 15.8 17.8 13.1 19.5 8.6 13.0 8.4 9.5 15.1 21.3 16.9 22.2 10.4 10.8 18.3 15.8 8.1 17.1 17.7 10.0 9.4 15.3 19.8 19.6 16.2 12.7 18.9 24.7 10.3 9.9 7.2 13.5 19.1 19.9 11.2 6.2 14.4 18.6 19.6 15.0 19.0 16.8 11.2 14.1 9.6 10.8 16.4 10.7 30.4 9.1 10.6 13.0 18.2 16.2 14.0 11.0 17.3 13.4 18.1 9.1 0.0 6.6 0.9 2.7 4.9 5.2 3.9 2.6 2.9 13.4 3.2 3.4 3.5 0.1 2.4 5.8 11.6 2.7 2.8 12.9 19.1 25.8 18.4 12.5 12.0 13.9 10.4 14.4 17.9 20.8 5.6 4.4 14.1 13.2 3.1 8.9 7.6 20.1 10.3 7.0 2.0 27.7 6.6 9.5 3.6 5.1 3.2 0.0 8.1 30.0 8.3 6.6 2.3 5.8 7.2 14.3 9.8 8.6 6.2 2.0 8.9 6.8 5.0 7.2 8.2 5.2 9.2 7.0 10.6 7.0 7.3 0.0 5.2 18.6 16.7 14.9 13.8 3.5 8.9 9.0 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Enzymes, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavorable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 15.5 15.0 19.1 19.8 23.5 23.1 16.6 19.5 22.6 15.0 16.3 17.3 15.5 14.9 19.2 19.0 17.6 19.6 19.4 13.2 15.7 13.4 14.4 17.3 13.5 26.8 22.1 14.7 29.1 23.8 16.3 14.4 14.4 21.9 18.1 14.5 10.9 14.9 15.6 21.4 22.1 16.1 16.5 12.4 25.0 16.3 16.8 20.1 12.2 15.6 12.1 19.6 17.3 18.8 11.2 14.9 3.1 15.7 4.3 10.2 8.5 15.4 10.4 11.3 19.2 11.5 14.8 16.2 17.4 8.7 19.2 16.7 11.1 12.7 19.4 22.8 9.3 10.0 14.3 18.9 15.3 8.9 12.6 26.4 15.4 26.8 18.7 20.9 30.8 18.2 20.9 20.6 19.9 18.8 12.3 14.1 14.5 33.3 6.2 11.9 17.1 12.5 33.3 26.8 9.8 24.5 21.1 14.6 26.7 11.9 15.7 26.9 12.2 10.8 22.6 18.1 8.6 8.8 17.3 15.6 27.7 10.8 16.7 30.4 10.8 20.8 17.9 12.9 32.7 14.4 1.2 15.7 0.5 8.1 11.9 7.7 10.4 8.6 7.7 14.9 11.2 10.2 7.7 3.1 4.3 7.5 8.8 5.6 8.5 19.1 23.5 19.5 22.6 15.7 13.4 22.1 14.7 21.9 20.1 11.9 16.2 35.0 22.3 21.3 8.0 6.4 12.7 10.7 4.5 12.2 2.0 19.4 5.0 14.1 16.4 17.5 6.3 0.0 12.8 18.8 13.9 10.4 28.9 8.6 41.5 7.9 6.9 7.4 88.1 36.5 13.0 39.6 16.9 23.4 9.6 5.8 12.2 5.8 12.0 11.2 11.1 12.9 16.5 21.7 18.3 18.1 12.9 18.7 17.4 18.4 TRMT11 "C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1" ENSG00000066651 "TRNA methyltransferase 11 homolog" Q7Z4G4 6 125986430-126039276 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 68.7;Rod photoreceptor cells: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030473 Approved "Nuclear bodies" Yes No "Nuclear bodies" "HPA030473: AB_2673493" "unprognostic (2.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.44e-1)" "unprognostic (1.13e-2)" "unprognostic (7.62e-2)" "unprognostic (9.69e-2)" "unprognostic (2.12e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-2)" "unprognostic (5.73e-2)" "unprognostic (7.35e-2)" "unprognostic (1.06e-2)" "unprognostic (4.74e-3)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" 10.0 12.6 14.3 12.5 17.7 3.6 15.5 33.9 19.4 17.9 12.6 9.4 11.2 16.1 25.9 15.1 13.2 12.8 12.9 16.1 15.0 12.6 18.8 28.0 10.1 12.4 12.7 16.4 19.2 10.4 15.9 38.1 13.3 15.4 12.8 15.0 14.8 11.7 13.8 10.6 7.4 20.6 15.7 15.2 9.6 12.9 9.8 11.1 8.0 18.0 9.8 13.7 11.5 12.5 8.0 4.7 1.3 2.0 7.5 11.7 4.0 8.6 6.5 13.2 2.8 6.9 7.5 7.8 7.4 11.3 8.1 12.0 19.9 9.1 12.2 13.6 4.8 17.0 12.0 14.3 7.5 12.4 9.8 20.5 9.5 12.9 24.8 11.9 15.6 2.6 7.5 7.2 9.5 15.6 12.8 3.6 5.2 21.6 2.4 8.4 13.2 7.2 8.2 9.3 8.6 8.3 4.9 10.0 7.3 9.5 5.4 16.6 7.8 9.1 8.3 16.1 9.8 6.5 12.6 3.6 5.4 4.1 12.4 12.9 6.7 0.7 3.3 11.0 12.1 9.4 1.3 2.0 0.0 6.8 1.5 11.7 8.0 9.1 7.5 4.1 6.7 11.4 10.4 0.3 7.5 0.7 4.7 6.8 4.0 14.3 17.7 33.9 19.4 15.0 12.6 12.7 16.4 15.4 11.1 6.0 22.4 12.3 23.6 11.8 57.1 11.4 20.4 25.4 25.0 7.0 68.7 16.7 16.6 15.9 7.7 10.5 8.0 0.0 14.1 12.2 17.6 11.7 18.4 21.5 6.4 19.1 8.7 4.9 6.5 3.0 23.9 6.9 3.3 14.4 9.6 20.7 12.4 14.0 23.0 23.3 75.1 6.5 12.1 9.5 7.0 8.8 12.5 5.7 12.8 16.0 TRMT1L C1orf25 ENSG00000121486 "TRNA methyltransferase 1 like" Q7Z2T5 1 185118098-185157072 "Predicted intracellular proteins" "Behavior, tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Spermatocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026728 Uncertain Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA026728: AB_1845641" "unprognostic (1.07e-2)" "unprognostic (1.31e-1)" "unprognostic (8.55e-3)" "unprognostic (2.96e-1)" "unprognostic (1.46e-2)" "unprognostic (8.95e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-2)" "unprognostic (2.32e-1)" "unprognostic (2.46e-3)" "unprognostic (1.32e-1)" "unprognostic (8.75e-2)" "unprognostic (1.16e-2)" "unprognostic (7.44e-2)" "unprognostic (9.45e-2)" "unprognostic (7.87e-2)" "unprognostic (2.26e-1)" 7.6 12.9 9.4 10.1 12.8 5.9 8.9 14.2 11.3 10.5 10.0 9.6 9.6 9.6 9.3 11.3 10.5 12.6 8.2 13.2 10.3 10.6 15.3 16.0 10.3 11.1 11.2 9.1 13.7 8.3 18.0 26.9 9.7 11.9 11.7 8.5 5.2 7.6 10.0 27.4 5.5 8.7 8.5 12.4 12.8 8.4 29.4 12.8 16.5 12.4 7.6 13.0 11.8 12.2 16.2 12.1 19.0 15.8 11.0 12.7 8.1 7.8 14.5 10.0 7.5 14.8 13.6 14.2 7.6 6.9 10.4 11.0 13.1 15.2 8.6 19.1 5.2 16.0 10.2 16.8 10.0 10.3 10.2 7.3 8.2 11.0 13.3 10.3 12.1 13.7 6.5 13.6 10.6 10.8 11.1 11.4 11.7 21.6 11.9 12.4 6.6 9.2 7.1 16.5 16.2 3.0 10.9 14.4 13.7 10.0 8.8 8.9 7.9 14.8 14.5 10.3 23.9 14.8 6.8 11.0 9.6 7.7 6.6 10.2 19.1 25.6 13.7 6.3 10.8 9.2 16.8 9.8 19.0 7.4 13.4 7.9 11.7 9.7 8.9 12.1 16.2 12.2 9.5 11.1 11.0 15.8 5.1 12.7 8.1 9.4 12.8 14.2 11.3 10.3 10.6 11.2 9.1 11.9 12.8 11.9 10.4 9.8 7.8 2.4 8.7 25.8 10.2 45.5 15.9 15.7 7.9 13.5 23.2 9.3 32.0 7.0 7.9 0.0 5.3 9.1 7.4 5.4 8.1 20.2 11.2 3.2 5.8 8.6 13.7 15.5 11.5 12.8 1.7 18.0 7.9 9.5 6.6 10.5 11.3 18.8 8.2 0.0 5.2 83.9 26.0 2.0 9.5 7.5 7.1 4.7 TRMU "FLJ10140, MTO2, TRMT" ENSG00000100416 "TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA Mitochondria "HPA000824: AB_2732393, HPA035273: AB_10602901, HPA043300: AB_2678415" "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favorable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavorable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 8.5 16.1 11.5 9.9 16.0 6.4 7.5 17.8 16.0 9.7 8.7 11.5 10.2 10.9 12.1 18.0 10.9 6.2 7.3 16.8 11.3 11.9 20.5 18.8 7.1 10.2 15.7 11.8 8.0 22.7 20.0 13.6 9.7 11.2 8.7 10.2 9.0 12.5 15.5 17.8 9.8 7.6 9.4 11.4 8.7 9.2 8.3 13.9 6.5 9.6 8.3 9.8 7.1 9.1 6.2 7.6 3.9 9.6 7.5 11.3 6.3 10.8 10.0 4.3 9.7 8.1 5.7 10.8 11.3 8.0 16.1 12.6 14.1 2.8 7.1 8.1 10.1 7.0 9.7 18.2 10.1 13.8 4.6 24.5 8.5 15.3 16.6 6.9 16.2 5.8 5.4 11.4 16.7 5.3 6.7 10.3 3.7 11.7 1.7 9.8 11.4 6.3 13.2 16.1 6.6 17.6 7.4 9.2 13.2 8.0 7.6 10.2 12.3 10.0 11.8 19.0 5.6 6.7 6.7 7.5 7.2 12.9 10.2 12.6 4.2 4.5 7.6 10.2 11.8 14.5 0.0 6.8 3.9 11.1 9.4 9.4 5.7 9.4 10.0 7.6 6.2 8.6 8.0 1.4 7.5 9.6 6.0 11.3 6.3 11.5 16.0 17.8 16.0 11.3 11.9 15.7 11.8 11.2 13.9 8.9 6.7 12.6 9.5 5.6 25.1 12.4 5.1 9.4 5.7 10.4 15.7 20.8 23.2 18.2 0.8 11.9 11.4 23.3 16.7 17.5 10.3 9.9 9.2 16.6 13.8 12.7 12.0 15.4 11.8 1.7 14.1 8.3 8.5 17.2 9.8 11.0 16.7 10.5 15.9 22.8 26.2 6.5 11.7 18.2 13.2 8.4 12.8 10.1 15.3 8.2 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.1;intestine: 19.5" "Group enriched" "Detected in many" 4 "Enterocytes: 28.8;Paneth cells: 10.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 16.1;neutrophil: 6.6" "Lineage enriched" "Detected in single" 30 "granulocytes: 16.1" "Cell line enhanced" "Detected in some" "BEWO: 7.7;HeLa: 4.5;Karpas-707: 2.6;RT4: 7.4;U-266/70: 2.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 2.9 0.0 1.3 0.5 1.2 2.5 1.1 1.3 1.2 0.8 13.3 0.2 1.0 7.2 0.4 0.2 0.6 0.4 1.0 0.5 1.9 1.2 3.1 0.2 1.5 0.2 2.6 0.0 0.4 0.2 3.8 4.9 0.2 1.6 1.7 17.5 0.4 1.1 0.0 1.6 0.8 19.5 0.7 5.0 3.9 0.2 1.7 0.5 1.6 0.3 1.1 2.1 0.5 0.6 0.3 0.3 16.1 0.1 0.5 0.1 0.0 0.1 1.7 0.2 0.2 0.0 0.0 7.7 0.1 0.0 0.0 0.1 2.1 0.2 0.6 0.0 0.1 0.3 0.3 0.5 0.5 0.0 0.1 0.2 0.2 4.5 0.3 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.1 0.2 0.3 0.0 2.6 0.1 0.9 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.3 0.0 7.4 0.3 0.0 0.0 0.1 0.1 0.4 0.3 0.0 0.0 0.2 1.1 0.2 0.0 2.8 0.0 0.2 0.1 0.1 0.3 16.1 0.1 1.9 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 6.6 0.5 0.1 0.3 0.0 0.0 1.3 1.2 1.3 1.2 1.9 1.2 2.6 0.0 1.6 0.5 0.0 1.7 0.0 1.7 0.1 0.2 0.6 0.0 1.4 2.3 3.5 0.0 0.2 0.0 0.0 2.5 0.7 28.8 0.0 0.0 0.1 0.3 1.1 0.0 0.0 0.0 0.0 3.5 4.9 0.3 0.4 0.0 0.2 0.0 0.0 3.3 0.1 0.0 10.5 0.4 0.0 2.3 0.0 0.3 1.5 2.3 0.9 0.1 0.0 2.6 0.9 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686815 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 91.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 13.3 10.8 6.6 14.7 9.0 12.8 12.1 19.5 9.3 11.8 11.7 8.1 9.7 9.9 16.5 10.7 9.4 11.0 8.2 19.1 5.5 4.9 16.0 20.0 10.8 10.6 12.4 5.2 16.6 11.6 91.8 14.6 14.3 10.2 9.7 10.3 28.6 11.5 13.5 10.8 11.7 12.8 12.8 9.8 11.1 10.3 6.9 10.0 14.5 12.6 6.9 12.6 12.9 12.3 7.0 4.7 4.4 3.4 5.7 7.6 2.0 8.5 8.5 7.1 7.9 20.6 15.5 8.7 10.8 15.0 6.9 9.1 11.7 4.7 18.6 5.3 12.4 17.8 14.4 9.5 7.9 9.9 10.3 5.7 14.8 13.1 6.1 18.8 15.3 11.5 14.4 9.4 7.8 14.7 10.1 5.5 11.8 16.7 14.3 12.5 13.4 9.8 7.5 5.4 11.8 5.3 10.8 9.9 9.1 9.6 20.2 5.9 7.5 7.4 11.9 14.5 13.1 7.4 16.7 8.4 11.0 5.2 50.9 12.4 9.7 21.5 17.9 11.9 31.3 10.2 3.8 3.4 3.9 6.6 3.2 7.6 5.6 4.8 4.4 3.7 7.0 4.4 5.2 4.4 5.7 3.2 4.7 4.8 2.0 6.6 9.0 19.5 9.3 5.5 4.9 12.4 5.2 10.2 10.0 17.9 25.3 18.2 14.9 28.0 22.9 21.4 28.1 24.1 7.9 12.2 11.8 18.5 3.3 9.7 25.2 18.5 16.9 23.3 11.1 8.0 17.0 21.2 16.3 35.0 12.7 20.6 17.7 15.4 18.6 17.9 24.5 17.0 18.6 14.4 17.3 9.1 12.8 12.9 19.1 9.6 21.5 12.9 13.7 13.6 19.4 21.1 13.6 17.5 16.3 9.0 TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432554-113435031 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "testis: 59.9" "Group enriched" "Detected in some" 101 "Early spermatids: 408.3;Late spermatids: 766.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.3;EFO-21: 2.1;RT4: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA027827 Enhanced NA NA "HPA027827: AB_10603138" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.2 0.0 1.3 0.2 2.1 0.0 0.4 0.4 0.2 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.6 0.1 0.0 0.1 0.1 0.3 0.0 0.4 0.0 0.5 0.2 0.2 0.3 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 408.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 766.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 5.8 3.2 0.0 0.0 0.0 0.0 0.0 TSSK2 "FLJ38613, SPOGA2, STK22B" ENSG00000206203 "Testis specific serine kinase 2" Q96PF2 22 19130808-19132623 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "testis: 95.7" "Group enriched" "Detected in some" 70 "Early spermatids: 1437.9;Late spermatids: 2322.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 1.6;HL-60: 1.8;SCLC-21H: 3.5;THP-1: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 95.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.0 1.6 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.8 0.0 0.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.7 3.3 0.8 1.4 0.5 0.0 0.2 0.1 0.9 0.3 0.0 0.3 1.2 0.0 0.0 1.0 0.4 0.0 0.0 0.5 0.1 0.8 0.3 0.7 0.2 0.5 0.2 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1437.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2322.2 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 6.5 0.0 26.9 11.5 0.0 0.0 0.0 0.0 0.0 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.1" "Group enriched" "Detected in some" 52 "Early spermatids: 242.3;Late spermatids: 839.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: AB_2675517" "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 1.1 2.0 0.8 1.7 0.8 8.2 1.1 3.9 0.8 1.3 0.9 0.8 1.4 2.5 1.8 2.9 0.8 1.3 1.0 0.9 0.8 0.0 0.9 1.3 1.4 2.4 0.8 0.8 2.0 1.2 0.0 0.8 0.8 1.0 1.0 0.0 0.8 1.4 0.8 1.7 3.4 2.9 0.8 0.8 3.4 1.2 68.1 0.8 0.8 1.3 0.8 0.8 0.9 1.1 0.6 0.1 0.1 0.7 0.3 2.3 0.1 2.3 2.3 6.0 3.5 0.0 1.2 5.4 0.7 1.1 0.0 0.0 0.5 1.2 1.2 0.9 0.0 1.0 3.7 0.0 0.0 0.0 3.5 7.2 2.7 9.8 3.7 4.4 1.1 3.4 0.1 0.9 0.0 1.3 6.3 0.0 4.6 3.1 5.8 0.0 0.6 1.4 1.5 1.5 0.4 1.2 1.9 1.7 4.4 0.0 1.9 1.8 3.8 0.8 2.8 4.1 4.4 1.9 2.7 2.9 2.1 3.4 3.0 2.4 8.5 2.8 1.8 3.7 3.9 0.5 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.2 0.0 0.1 0.6 2.3 0.9 0.1 0.3 0.5 0.0 0.0 0.1 0.8 0.8 3.9 0.8 0.8 0.0 0.8 0.8 1.0 0.8 0.0 0.3 0.0 0.4 0.1 0.1 0.3 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.2 242.3 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 839.4 8.6 0.0 0.0 0.0 0.3 0.9 0.2 0.0 8.9 0.6 1.4 6.5 0.0 10.3 3.8 0.0 0.2 0.0 0.2 0.2 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205697-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 46.1" "Cell type enriched" "Detected in some" 15 "Early spermatids: 178.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" NA NA "Cell Junctions" "HPA060660: AB_2684339, HPA077103: AB_2732332" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 0.6 0.9 0.6 1.7 0.6 3.1 0.6 1.5 1.8 0.6 0.6 0.6 0.6 1.5 0.8 0.9 1.4 0.8 1.7 0.6 0.6 0.4 0.6 0.6 0.8 2.8 0.6 0.6 0.8 0.9 0.0 0.6 0.6 0.6 0.6 0.0 0.6 1.4 0.6 1.0 4.7 1.6 0.6 0.6 1.5 0.6 46.1 0.6 0.6 1.4 0.6 0.6 1.0 0.6 2.1 1.7 2.0 1.0 1.8 2.0 0.7 1.0 4.1 4.0 1.5 0.1 0.0 4.3 1.6 0.1 0.0 0.0 2.1 3.7 3.1 0.9 0.1 0.8 3.8 0.0 0.1 0.0 1.6 3.1 3.5 4.8 3.0 0.0 1.5 3.8 0.0 0.0 0.0 0.6 3.6 0.1 3.7 1.3 2.0 0.0 3.8 3.6 1.7 0.7 0.9 3.2 3.0 1.6 2.7 0.0 5.3 2.2 2.1 2.7 2.5 0.8 1.8 1.6 1.8 1.4 2.9 1.8 3.8 1.3 4.3 4.8 4.8 1.0 2.8 0.9 0.0 1.0 2.0 2.0 1.0 0.7 2.0 1.6 1.6 0.6 2.1 1.6 1.7 2.0 1.8 0.9 1.7 0.7 0.7 0.6 0.6 1.5 0.6 0.6 0.4 0.6 0.6 0.6 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 178.8 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.1 0.0 0.0 0.0 TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515685 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "testis: 50.8" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5597.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (2.12e-1)" "unprognostic (7.89e-2)" "unprognostic (7.26e-2)" "unprognostic (6.64e-2)" "unprognostic (3.39e-1)" "unprognostic (7.20e-5)" "unprognostic (3.38e-1)" "unprognostic (5.51e-3)" "unprognostic (5.17e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-4)" "unprognostic (2.28e-2)" "unprognostic (5.34e-3)" "unprognostic (2.74e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-3)" "unprognostic (9.89e-2)" 0.9 1.2 1.0 1.2 1.5 1.3 1.0 0.9 1.9 0.9 1.1 2.2 1.6 2.1 0.9 3.7 1.1 1.1 1.0 0.7 1.2 0.8 1.8 2.2 0.7 1.2 2.5 1.0 0.9 3.3 1.1 1.0 0.6 1.3 1.4 0.6 0.9 1.3 1.0 1.0 2.7 1.9 1.2 1.9 2.1 1.7 50.8 1.7 3.1 2.0 0.1 1.7 1.1 1.0 3.1 1.0 2.2 0.7 0.4 3.8 0.8 1.6 2.7 0.1 1.1 0.4 1.0 8.0 1.1 0.5 0.6 0.3 4.2 1.3 1.4 2.0 0.0 0.5 1.4 0.5 1.1 0.2 1.0 1.9 0.7 1.7 0.9 1.2 0.9 3.2 0.6 1.0 0.6 1.9 0.6 0.3 5.4 1.9 0.8 0.0 0.5 3.4 2.0 3.7 0.8 4.4 2.7 0.7 1.2 0.1 0.5 0.6 2.9 1.6 0.4 1.4 0.4 2.6 0.7 0.3 2.0 0.6 3.9 1.7 3.5 1.4 0.8 2.2 1.2 1.9 0.0 0.6 2.2 0.8 0.2 1.1 3.1 1.7 2.0 0.3 1.9 3.8 2.1 1.1 0.4 0.7 1.0 1.0 0.8 1.0 1.5 0.9 1.9 1.2 0.8 2.5 1.0 1.3 1.7 0.0 0.0 0.0 0.2 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1053.4 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.3 0.6 5597.9 44.3 0.0 1.7 0.0 0.0 0.0 0.1 0.0 53.7 0.1 0.0 19.4 0.6 51.3 21.7 0.1 0.1 0.0 0.0 0.0 TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Nucleoplasm, Nucleoli" Cytosol "HPA016810: AB_1858434, HPA023964: AB_1858435, HPA036304: AB_2675049" "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (8.52e-2)" "unprognostic (9.29e-2)" "unprognostic (8.71e-2)" "unprognostic (1.61e-1)" "unprognostic (2.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (6.74e-2)" 22.9 22.1 34.0 18.7 36.5 12.0 23.4 39.2 40.0 34.9 20.6 15.9 26.7 13.0 21.6 33.3 15.3 19.5 19.0 21.5 29.1 16.5 21.4 17.0 15.4 14.3 17.7 27.5 34.5 25.8 27.4 50.4 15.2 34.7 28.9 19.9 16.1 24.5 25.4 21.6 16.1 16.8 21.6 21.7 13.6 21.3 19.5 19.9 19.7 35.4 11.1 15.1 23.3 18.9 10.6 12.8 4.8 5.7 9.1 18.6 3.8 21.7 7.8 36.3 6.8 35.0 51.1 12.6 24.0 29.9 10.8 14.7 10.2 11.0 18.8 8.4 40.2 10.1 7.2 10.9 14.8 15.3 19.9 7.8 38.0 11.6 13.4 12.8 21.2 12.3 26.4 9.1 11.0 9.8 21.8 16.0 16.7 22.8 22.1 20.3 16.8 20.6 5.5 10.3 14.5 13.2 27.6 17.4 9.9 12.6 16.9 27.7 21.1 29.8 17.1 15.4 8.7 19.4 8.3 20.9 15.5 6.2 19.0 9.0 22.2 15.9 18.8 25.6 21.2 11.7 2.9 4.4 4.8 9.1 4.8 13.6 9.5 10.6 12.3 7.9 10.6 18.6 11.3 0.7 9.1 5.7 12.8 7.2 3.8 34.0 36.5 39.2 40.0 29.1 16.5 17.7 27.5 34.7 19.9 116.1 118.5 109.7 81.2 58.5 344.6 127.3 56.0 75.0 101.2 71.5 214.0 39.6 140.9 74.9 160.4 67.6 60.1 0.0 65.5 79.7 132.8 164.9 62.4 80.5 56.3 311.4 182.6 102.5 80.0 149.3 194.5 74.4 200.8 61.3 133.8 187.6 72.0 84.2 245.4 81.7 228.9 51.8 103.8 264.1 280.4 54.8 44.1 76.7 118.3 90.4 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.3;testis: 31.7" "Cell type enhanced" "Detected in many" 15 "Early spermatids: 19.9;Erythroid cells: 23.3;Spermatocytes: 63.4;Spermatogonia: 28.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol NA Yes "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 1.1 1.4 0.3 3.2 0.4 13.9 1.0 0.3 0.4 1.0 2.7 0.2 0.2 2.2 0.5 1.0 6.5 0.3 0.4 1.5 0.4 0.3 0.9 0.6 1.2 4.6 0.4 0.2 0.4 0.5 0.0 0.3 3.0 0.6 0.6 3.6 0.3 1.2 0.6 0.3 2.0 2.8 0.7 0.8 2.1 1.8 31.7 0.2 58.3 0.5 2.6 5.4 0.8 1.8 1.7 0.0 1.1 0.0 1.1 4.0 0.8 13.3 8.0 24.0 19.6 1.1 3.5 13.6 15.5 9.5 22.7 27.8 10.9 10.2 19.8 12.1 6.6 23.8 17.3 21.1 9.5 31.6 18.0 17.0 18.3 10.6 8.9 0.0 21.5 11.9 0.4 1.0 15.8 10.1 3.3 12.8 27.9 19.9 20.4 19.2 9.9 12.2 15.5 14.1 12.0 9.7 11.0 43.8 8.2 5.7 8.6 16.5 9.7 9.1 9.9 5.6 13.5 9.3 16.3 5.3 10.2 10.2 6.6 24.7 4.6 15.5 11.0 3.6 20.0 8.7 0.0 0.0 1.1 0.6 0.0 0.6 0.9 1.0 1.6 0.0 1.7 0.3 0.5 0.3 1.1 0.0 0.0 4.0 0.8 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.2 0.6 0.2 3.0 0.6 0.0 0.5 1.1 0.0 0.7 0.0 4.0 3.4 0.0 2.0 4.1 3.3 0.4 19.9 0.1 0.2 23.3 0.2 13.1 0.8 0.2 1.1 0.0 5.2 0.0 1.7 0.0 2.4 12.8 0.9 1.2 0.0 9.0 1.0 0.3 0.4 0.0 0.7 0.0 1.2 6.5 0.2 63.4 28.5 0.3 3.1 0.0 1.2 0.7 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482154-112541739 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Erythroid cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA066819: AB_2685728" "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 4.4 4.0 9.9 4.2 11.9 7.1 11.3 5.0 12.5 3.3 4.1 9.2 2.5 3.1 4.6 4.2 5.2 3.2 4.9 10.3 9.4 6.5 3.9 3.3 5.9 4.4 8.1 5.3 3.2 3.8 4.1 2.4 5.3 5.9 3.2 3.9 2.6 3.0 3.7 13.1 6.0 3.2 5.8 5.4 4.0 3.2 3.0 6.5 5.1 4.2 5.2 3.8 4.8 2.9 1.8 1.2 2.7 1.3 1.0 1.3 0.5 3.7 2.9 3.7 8.2 4.4 6.3 1.4 6.4 5.3 6.9 5.9 3.5 1.4 3.5 3.6 5.5 4.5 2.6 6.4 3.3 8.3 2.4 3.6 2.9 4.1 4.4 2.0 4.1 1.5 2.8 2.3 10.0 5.3 3.1 5.8 2.4 4.8 2.8 5.4 1.9 3.6 2.3 3.2 1.1 5.8 3.9 4.1 1.9 2.1 2.9 7.8 5.4 5.0 1.7 8.9 2.5 1.7 2.4 5.8 8.2 6.0 6.4 4.8 1.6 3.1 2.9 9.0 3.1 3.5 2.7 1.3 1.0 1.3 0.8 1.1 0.8 1.0 1.0 0.4 1.8 0.9 1.1 2.4 1.0 1.1 1.2 0.8 0.5 9.9 11.9 5.0 12.5 9.4 6.5 8.1 5.3 5.9 6.5 11.9 8.3 3.7 4.2 18.0 16.4 32.0 5.1 2.7 7.9 12.2 11.8 2.6 0.0 6.0 6.1 13.0 5.0 46.7 8.3 2.1 9.4 5.0 0.0 9.4 10.2 7.9 10.9 20.9 24.8 3.6 2.8 15.5 6.8 10.8 5.5 9.1 8.6 5.8 5.3 4.9 21.2 6.5 9.0 1.9 4.3 15.7 1.0 6.1 5.2 3.7 TTLL10 "FLJ36119, TTLL5" ENSG00000162571 "Tubulin tyrosine ligase like 10" Q6ZVT0 1 1173884-1197935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 48.2" "Group enriched" "Detected in many" 8 "Early spermatids: 234.3;Late spermatids: 619.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "pons and medulla: 2.2" "Cell type enriched" "Detected in single" 29 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 29 "NK-cells: 2.9" "Cell line enriched" "Detected in single" 24 "SCLC-21H: 23.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA042712 Uncertain NA NA "HPA042712: AB_10797019" "unprognostic (1.74e-1)" "unprognostic (7.95e-2)" "unprognostic (2.66e-3)" "prognostic favorable (1.61e-5)" "unprognostic (5.33e-2)" "unprognostic (2.68e-3)" "unprognostic (4.93e-3)" "unprognostic (2.14e-3)" "unprognostic (4.50e-1)" "unprognostic (3.69e-2)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "unprognostic (6.00e-4)" "unprognostic (8.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.12e-1)" "unprognostic (4.39e-2)" 1.2 0.0 0.1 0.1 0.5 0.0 0.6 0.1 0.2 1.7 0.1 1.0 0.1 0.0 0.2 1.1 0.1 10.9 0.1 0.1 0.3 0.3 0.1 0.1 3.1 0.1 0.1 0.3 0.7 0.1 0.0 1.3 1.5 2.2 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.5 48.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.2 0.3 0.3 0.1 0.3 2.2 0.3 0.0 0.3 0.0 0.5 1.5 0.0 0.6 2.5 54.9 2.3 0.0 2.0 0.0 0.0 0.2 234.3 0.5 0.0 0.0 1.2 0.7 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 619.5 4.9 0.0 0.0 0.0 3.1 0.2 0.9 0.0 4.2 0.0 0.0 6.5 0.0 2.8 2.1 1.8 0.1 0.0 4.1 1.0 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 136.5;skeletal muscle: 713.8;tongue: 227.0" "Cell type enriched" "Detected in many" 134 "Cardiomyocytes: 19161.7" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 4.9" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 25000000 "CAB022682: , HPA007042: AB_1080292, HPA030048: AB_2732451" "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 23.7 0.3 0.2 0.3 0.3 0.9 0.3 0.2 0.4 0.2 0.2 0.0 0.0 0.2 0.2 21.3 8.3 0.2 0.3 136.5 0.2 0.2 0.2 0.2 0.4 0.4 0.2 0.0 0.3 0.4 0.2 0.3 0.3 0.0 0.7 0.2 0.0 11.6 0.2 713.8 0.3 0.2 0.2 0.3 0.3 0.2 0.4 0.0 0.0 5.6 227.0 15.8 0.3 0.2 7.0 0.3 1.9 0.3 5.0 7.3 0.1 0.7 0.3 1.9 1.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 1.8 0.3 2.4 0.6 0.0 1.8 1.8 0.0 0.0 0.0 2.4 2.0 3.7 2.7 1.1 0.0 0.3 0.8 2.4 0.0 0.0 0.0 1.7 1.4 1.8 2.2 1.2 0.4 0.4 1.6 2.5 0.4 0.2 1.8 1.3 4.9 1.3 0.0 0.6 1.1 1.7 0.4 1.3 0.0 1.7 0.8 2.4 1.6 0.0 0.0 0.9 0.4 3.6 0.4 3.5 0.1 1.1 0.9 1.9 0.3 0.7 0.5 0.2 0.2 6.9 1.2 0.9 0.2 7.0 2.7 3.5 1.3 5.0 0.2 0.3 7.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 14.9 142.6 2.2 0.2 0.8 28.9 19161.7 17.8 5.3 11.4 0.0 19.6 0.4 1.7 7.7 35.3 0.7 0.0 0.0 23.6 0.2 0.5 0.1 9.3 0.5 0.2 15.9 4.1 2.5 0.0 4.3 1.1 0.4 0.0 0.0 0.0 10.3 0.9 0.0 4.2 0.0 26.3 0.0 1.4 5.7 0.2 0.1 0.3 4.9 0.0 0.0 UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease mutation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm NA NA 16000000 Nucleoplasm "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" 45.6 63.0 56.0 47.2 50.6 42.0 38.3 58.1 75.7 48.0 39.3 55.9 44.9 36.3 52.9 34.1 59.4 56.0 39.9 48.7 49.5 39.9 51.1 60.0 42.0 48.2 47.7 62.3 57.6 34.9 78.8 55.5 39.1 47.6 40.2 35.5 41.0 47.5 45.7 77.7 56.1 37.9 59.4 35.5 53.4 38.7 36.0 48.6 52.7 65.0 43.9 54.0 39.2 52.7 28.9 30.6 32.6 36.0 25.6 29.0 24.1 46.0 47.9 54.8 83.2 37.5 34.2 24.2 30.7 32.7 44.2 36.0 38.0 35.2 34.4 20.4 61.4 65.4 44.6 68.7 65.3 32.4 28.5 69.8 21.5 53.1 30.5 26.4 36.2 46.5 32.1 34.2 64.2 50.1 31.6 57.8 41.4 23.3 30.9 43.8 58.4 34.1 32.0 58.4 27.9 74.9 39.8 38.3 58.5 35.3 49.7 35.5 26.7 91.4 44.5 20.4 61.4 61.8 22.6 42.2 33.2 38.5 47.7 28.6 21.2 22.0 49.1 34.1 25.9 39.6 17.4 27.0 27.4 29.0 36.0 25.4 28.9 24.0 25.9 30.6 22.0 19.1 23.4 32.6 25.6 32.8 20.8 28.2 24.1 56.0 50.6 58.1 75.7 49.5 39.9 47.7 62.3 47.6 48.6 47.6 32.5 35.6 30.6 29.9 25.4 44.0 71.4 29.4 29.6 78.5 15.7 42.1 29.9 67.7 29.3 28.1 83.5 23.3 78.8 52.0 36.1 52.8 17.4 40.8 53.6 11.1 55.2 46.1 45.1 41.8 39.1 34.8 18.6 66.7 64.2 20.0 108.7 57.9 61.9 49.5 24.4 38.8 40.3 8.8 19.6 36.8 59.5 26.6 52.5 48.1 UBA2 "ARX, FLJ13058, HRIHFB2115, SAE2" ENSG00000126261 "Ubiquitin like modifier activating enzyme 2" Q9UBT2 19 34428352-34471251 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Sertoli cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041436 Supported Supported Nucleoplasm NA NA 9400000 Nucleoplasm "HPA041436: AB_2677479" "unprognostic (2.37e-1)" "unprognostic (3.17e-1)" "unprognostic (2.13e-2)" "unprognostic (1.36e-3)" "unprognostic (6.39e-3)" "unprognostic (8.72e-3)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.96e-2)" "unprognostic (2.14e-2)" "unprognostic (1.21e-1)" "unprognostic (2.58e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (2.11e-2)" "unprognostic (2.00e-1)" "unprognostic (1.88e-1)" 49.2 23.5 25.1 29.5 28.4 30.6 70.9 44.3 30.4 26.5 25.4 20.7 24.0 17.8 32.3 24.2 27.4 25.1 23.7 31.0 25.6 27.7 22.8 25.5 24.5 37.8 26.9 23.2 30.3 29.4 28.8 26.8 39.1 25.1 25.1 23.9 20.7 20.9 31.5 56.3 29.2 20.4 28.8 27.4 28.6 20.9 56.7 19.9 55.9 25.9 27.1 34.4 29.2 38.9 8.6 10.8 7.7 6.2 8.5 13.0 3.6 28.9 42.4 43.5 18.0 23.6 19.3 17.8 22.6 19.5 29.3 32.8 36.3 17.7 54.2 35.0 18.4 18.2 11.8 46.0 17.6 41.4 38.8 31.1 57.5 21.7 36.2 30.5 45.6 25.0 13.9 22.5 20.7 36.5 19.7 22.9 23.4 56.9 30.8 25.7 28.9 35.1 25.3 32.6 45.3 14.7 28.0 30.0 24.1 20.6 30.3 37.0 36.3 20.6 19.0 30.4 29.6 13.6 56.0 14.8 33.0 23.0 21.0 40.5 32.5 46.1 52.5 20.9 34.9 29.0 5.9 4.8 7.7 8.4 5.0 11.2 8.5 10.5 12.1 6.0 8.6 13.0 10.4 0.6 8.5 6.2 10.8 8.0 3.6 25.1 28.4 44.3 30.4 25.6 27.7 26.9 23.2 25.1 19.9 23.8 33.6 45.4 55.0 77.3 59.3 31.9 22.9 29.4 30.7 17.4 39.3 60.6 28.2 38.5 10.7 46.7 15.5 23.3 36.4 83.5 49.3 42.2 38.1 23.6 41.7 44.5 44.2 20.3 31.3 18.0 40.3 35.2 72.6 45.1 28.5 45.3 35.2 21.0 49.8 28.3 35.0 265.1 176.3 193.3 196.1 81.2 77.6 35.2 44.9 68.2 UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA 9600 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: AB_10670578, HPA034874: AB_2674368, HPA065335: AB_2685473" "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (5.56e-3)" "unprognostic (9.26e-2)" "unprognostic (9.35e-3)" "unprognostic (5.53e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.08e-1)" "unprognostic (6.18e-2)" "unprognostic (1.60e-3)" "unprognostic (9.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-3)" "unprognostic (2.61e-3)" "unprognostic (9.24e-2)" "unprognostic (7.80e-3)" "unprognostic (2.52e-1)" 19.1 25.3 29.7 22.2 31.0 53.7 26.8 30.9 31.4 20.3 19.7 31.3 15.9 16.1 22.8 25.4 25.4 19.5 18.4 38.2 23.8 22.7 24.7 17.6 19.3 28.7 37.5 21.2 20.4 15.1 17.9 28.0 27.8 40.8 22.6 22.6 21.8 28.0 20.4 25.0 27.6 21.9 24.0 30.2 27.8 17.3 13.5 31.9 28.4 18.2 17.2 31.0 22.9 20.4 18.9 22.3 35.6 27.8 20.2 22.2 26.0 26.8 11.4 28.1 17.1 26.3 34.9 21.7 24.1 27.3 26.3 26.5 14.1 19.0 20.5 7.0 25.9 26.5 15.5 21.6 27.6 30.0 37.3 13.7 27.7 21.5 14.2 20.3 27.1 23.3 27.4 18.5 24.8 20.8 32.4 33.8 16.9 11.4 17.6 34.6 9.6 17.8 18.3 24.9 34.1 9.8 13.9 20.8 18.8 41.9 34.4 12.1 16.9 25.4 18.5 20.6 31.6 12.6 26.7 25.6 20.0 17.6 25.9 33.4 20.2 32.3 24.4 20.5 30.2 25.4 34.7 25.4 35.6 14.3 27.8 16.1 18.9 18.9 17.6 22.3 16.0 17.9 18.0 24.4 20.2 27.7 11.4 22.2 26.0 29.7 31.0 30.9 31.4 23.8 22.7 37.5 21.2 40.8 31.9 32.8 28.9 17.1 23.8 30.0 21.0 57.2 20.4 37.5 23.9 33.2 37.3 64.4 16.6 30.4 10.9 27.1 14.3 0.0 20.5 47.2 31.1 21.5 40.5 16.2 30.1 31.8 17.9 20.3 43.2 7.9 37.4 39.1 28.7 53.3 15.3 27.7 25.3 8.6 35.7 26.4 44.9 25.8 29.3 32.3 33.0 37.4 47.5 33.8 16.6 28.2 UBA6 "FLJ10808, UBE1L2" ENSG00000033178 "Ubiquitin like modifier activating enzyme 6" A0AVT1 4 67612652-67701179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Urothelial cells: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037001 Approved Enhanced Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA037001: AB_10672787" "unprognostic (2.52e-1)" "unprognostic (4.89e-2)" "unprognostic (3.97e-3)" "unprognostic (2.81e-1)" "unprognostic (3.67e-2)" "unprognostic (4.92e-2)" "unprognostic (3.55e-3)" "unprognostic (6.06e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-2)" "unprognostic (3.38e-2)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.01e-5)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.05e-3)" 16.8 12.6 14.1 14.1 16.6 22.7 13.0 18.0 16.0 17.0 10.5 14.6 7.0 12.2 16.7 10.0 20.5 9.9 12.4 9.5 12.0 12.0 10.2 16.4 14.5 17.3 18.7 11.2 14.3 10.9 17.4 44.8 18.5 17.7 12.7 13.2 7.5 13.7 10.4 10.1 12.6 15.3 13.4 20.7 16.9 13.9 14.6 18.6 27.1 12.3 13.3 19.9 15.7 19.5 5.6 5.1 9.3 4.0 9.7 5.8 1.9 15.1 8.5 14.1 11.0 7.0 8.2 9.5 31.4 12.3 14.4 16.9 8.9 20.5 19.2 11.2 12.9 14.7 9.0 14.5 15.6 21.8 22.1 4.0 12.3 15.0 8.3 6.0 21.6 9.5 5.9 5.0 18.6 11.3 9.9 12.7 9.9 29.2 11.4 17.0 5.7 22.4 4.9 8.3 10.8 10.3 13.3 28.9 7.1 11.8 17.2 6.9 8.7 17.7 12.6 5.9 12.3 8.4 5.8 18.3 13.4 15.1 10.8 13.7 8.2 6.4 19.4 23.8 6.0 12.8 9.3 3.0 4.6 4.4 3.9 4.8 5.6 5.1 5.8 3.7 5.2 3.9 4.5 2.2 9.7 4.0 5.1 4.2 1.9 14.1 16.6 18.0 16.0 12.0 12.0 18.7 11.2 17.7 18.6 23.8 20.8 33.8 52.9 62.3 46.2 14.4 12.7 25.4 20.5 15.7 51.1 22.4 3.3 21.4 1.4 34.4 21.2 0.0 14.8 12.9 28.2 64.5 30.1 17.3 20.5 31.8 31.0 17.8 27.9 4.0 19.8 35.3 23.6 33.3 24.7 19.8 36.7 21.0 18.7 10.2 42.3 19.4 23.0 37.9 35.1 40.4 49.2 29.9 19.6 126.8 UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805207-49813946 "Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "granulocytes: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 22.7;HEL: 21.2;HMC-1: 41.2;HSkMC: 19.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 1400000 "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: AB_2683631" "prognostic favorable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.48e-4)" 11.3 12.1 6.8 22.0 7.5 16.0 11.5 2.0 6.7 10.8 12.7 14.4 25.4 19.6 17.2 31.6 17.7 12.9 33.1 9.1 6.7 3.9 15.9 11.9 18.8 28.2 6.0 6.2 19.1 9.5 1.4 8.4 8.9 9.4 18.5 12.1 14.2 24.5 34.2 3.3 9.0 25.5 11.3 7.7 35.9 13.2 3.4 5.9 20.4 17.8 18.4 23.5 12.6 13.1 12.4 14.3 24.8 21.7 11.1 11.8 13.0 4.3 0.0 0.3 0.1 12.2 12.9 1.4 2.3 10.6 16.9 22.7 0.0 9.3 0.1 1.9 8.6 7.3 2.4 0.0 4.2 1.5 11.3 0.0 21.2 0.2 1.3 9.0 2.0 41.2 19.8 0.2 6.6 0.4 11.8 8.5 0.7 0.0 1.3 3.9 0.1 4.3 5.1 0.0 0.0 0.4 5.5 0.4 0.7 3.5 8.6 0.0 0.3 2.8 4.2 1.4 0.2 0.4 14.1 3.7 3.3 0.4 1.4 0.9 0.0 0.0 0.1 9.2 7.5 0.7 13.9 14.7 24.8 11.8 21.7 10.3 12.3 10.8 10.5 14.3 12.4 9.9 8.9 4.6 11.1 17.2 5.2 10.6 13.0 6.8 7.5 2.0 6.7 6.7 3.9 6.0 6.2 9.4 5.9 29.8 23.6 22.9 5.9 3.4 0.1 6.9 15.3 2.7 13.6 12.2 0.0 4.5 0.0 7.6 4.5 14.3 35.5 0.0 6.9 2.2 8.9 5.1 80.8 6.7 18.2 0.0 9.1 17.8 21.9 24.1 10.3 10.6 0.0 10.8 19.5 2.9 5.1 12.9 10.6 4.1 1.1 6.5 7.1 0.9 0.4 4.1 2.4 27.4 15.3 5.0 UBE2A "HHR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574467-119591083 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Syncytiotrophoblasts: 425.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 24.8 20.6 26.7 23.1 24.6 16.8 32.5 20.2 24.2 23.7 32.8 23.9 20.2 21.7 23.8 26.7 37.2 20.3 21.2 42.2 23.6 22.1 32.2 26.6 22.8 26.3 26.8 19.7 18.7 17.2 24.3 18.2 112.4 24.7 20.4 30.2 20.0 21.0 22.6 46.8 23.6 29.2 27.9 29.1 25.1 20.4 17.0 19.5 36.3 23.2 32.8 31.5 26.7 24.0 21.0 29.0 34.1 36.3 12.8 21.2 17.4 31.1 26.3 16.6 14.0 29.0 35.8 15.5 32.4 28.9 38.5 36.6 13.6 21.5 24.7 32.9 35.6 64.7 22.5 23.6 17.1 37.2 34.2 14.0 10.9 21.0 12.1 26.6 27.2 18.8 24.4 24.5 37.0 16.1 27.2 26.7 22.1 13.4 22.1 43.6 33.0 42.0 25.8 27.6 32.9 29.8 21.5 17.6 23.0 31.1 20.5 12.7 13.1 43.0 19.8 23.5 21.6 17.3 23.9 26.0 24.8 11.1 48.9 36.5 21.4 34.8 24.3 26.4 34.6 19.3 16.5 22.7 34.1 18.1 35.4 14.3 21.0 15.7 15.8 29.0 18.8 10.0 14.3 30.1 12.8 36.3 23.0 21.2 17.4 26.7 24.6 20.2 24.2 23.6 22.1 26.8 19.7 24.7 19.5 95.3 39.2 51.3 71.2 110.8 14.0 62.9 48.4 83.0 53.4 38.4 29.5 150.4 86.2 88.0 32.0 62.8 76.2 46.7 89.2 129.6 86.9 77.3 55.4 31.6 116.0 7.9 43.7 44.2 59.6 10.6 34.2 89.3 79.2 168.7 43.9 37.6 102.2 80.7 38.2 92.2 34.3 45.3 103.2 39.1 30.0 111.8 425.3 58.0 43.9 88.5 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371179-134391992 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 83.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 83.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 17.7 27.7 20.4 17.0 16.6 25.9 22.8 16.2 28.3 13.8 18.0 7.9 11.6 14.4 19.4 17.0 25.6 13.6 18.3 59.2 20.3 16.4 17.8 19.8 21.8 18.7 13.8 18.7 16.7 26.4 7.8 16.2 27.8 17.6 15.4 15.1 10.2 16.1 18.5 106.5 15.9 16.2 21.6 15.1 16.6 14.1 21.7 12.7 13.2 18.2 34.0 16.3 19.2 22.8 9.6 8.8 83.3 14.1 9.6 14.6 10.5 35.5 9.3 19.6 18.6 17.1 18.5 31.6 26.7 14.1 17.2 20.5 28.3 23.9 19.4 32.3 17.0 47.0 14.2 14.8 19.7 18.8 30.7 16.0 10.6 25.9 30.3 20.0 12.6 21.9 15.9 27.0 15.6 13.2 23.2 14.7 16.2 19.5 35.3 15.5 20.7 20.0 33.4 8.4 10.6 8.9 20.2 21.6 27.0 15.4 27.5 26.5 20.6 21.0 9.9 46.4 22.2 21.3 34.8 29.1 20.0 14.0 26.9 29.2 29.5 40.3 27.4 22.6 23.9 19.9 34.7 11.5 31.2 9.4 12.5 8.6 9.6 12.0 9.5 7.9 9.6 14.6 12.3 83.3 9.6 14.1 8.8 14.1 10.5 20.4 16.6 16.2 28.3 20.3 16.4 13.8 18.7 17.6 12.7 68.5 53.6 80.6 311.1 324.0 73.3 287.9 109.5 50.9 37.5 71.5 76.6 127.7 145.9 138.0 194.0 119.9 104.0 210.2 148.2 103.0 162.4 304.2 116.3 90.1 106.8 82.6 126.4 82.3 121.3 244.2 143.5 139.6 215.9 189.4 109.5 124.2 180.7 129.8 106.4 130.7 89.5 148.8 178.2 201.6 171.6 323.2 605.1 89.5 82.7 405.3 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 130.8" "Group enriched" "Detected in many" 5 "Erythroid cells: 397.1;Extravillous trophoblasts: 368.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Supported "Plasma membrane,Cytosol" Yes Yes "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 3.1 2.3 0.4 24.0 0.9 25.1 4.3 0.4 0.7 3.8 9.5 0.4 0.8 7.8 2.0 2.6 25.6 0.6 3.2 2.8 0.5 0.4 2.1 2.1 4.6 15.6 0.6 0.5 1.2 1.3 0.0 0.6 12.6 0.9 1.3 11.7 0.7 3.7 0.6 1.0 8.3 10.0 3.5 1.2 11.6 7.0 15.3 0.5 130.8 0.8 17.6 26.3 2.8 7.8 1.2 0.9 2.7 0.6 2.4 10.0 4.2 39.3 28.9 52.2 25.0 1.4 3.2 30.0 31.3 15.9 51.6 37.1 94.9 45.6 41.8 30.7 14.9 64.3 38.9 0.2 33.5 52.7 17.8 27.5 12.9 22.2 24.9 0.4 18.4 32.3 1.0 3.6 34.9 34.2 7.8 25.1 26.7 0.2 35.6 42.4 64.9 30.3 5.2 31.3 44.8 69.3 32.2 47.3 0.2 17.4 13.7 30.1 25.1 49.3 36.1 19.8 27.4 36.5 27.1 9.1 46.3 40.5 31.4 60.5 11.3 0.3 46.5 28.1 13.1 43.8 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.2 2.3 0.9 0.2 0.2 0.1 2.7 2.4 0.6 0.5 10.0 4.2 0.4 0.9 0.4 0.7 0.5 0.4 0.6 0.5 0.9 0.5 0.0 5.9 29.5 3.6 15.3 0.0 0.0 2.5 0.0 7.9 0.0 0.0 15.5 0.0 0.8 5.8 0.2 5.5 397.1 0.4 368.9 5.1 2.7 5.7 3.9 75.1 0.0 1.2 22.7 19.9 5.4 0.9 9.3 0.0 1.8 12.8 0.0 1.0 6.2 0.0 0.0 0.0 0.0 1.9 6.1 18.0 10.2 26.1 10.1 15.1 8.2 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334975-58370753 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 74.9" "Cell type enhanced" "Detected in many" 4 "Basal keratinocytes: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 41.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 8.2 10.6 8.1 10.0 7.9 17.1 7.5 7.7 9.0 6.3 7.3 5.5 4.8 4.7 8.5 5.5 8.2 5.5 6.4 25.6 7.6 7.2 5.5 5.4 7.0 13.7 8.1 6.7 5.9 4.8 5.3 7.4 6.8 7.4 6.5 7.9 3.5 6.4 5.0 74.9 4.6 5.8 8.8 8.4 11.0 5.6 3.2 8.4 5.5 6.0 25.1 7.1 9.5 10.0 3.7 7.2 41.0 13.7 2.8 3.5 7.1 10.7 5.8 10.9 14.0 22.4 18.1 7.1 7.1 12.1 8.1 12.0 11.8 9.3 0.0 11.2 10.6 6.0 9.8 21.1 10.3 11.5 11.1 12.4 2.8 2.1 6.7 14.7 8.5 6.9 20.9 11.6 8.5 15.8 11.0 16.2 7.5 5.5 4.5 11.0 3.4 9.1 9.5 13.4 6.5 9.2 7.7 9.9 5.9 12.2 6.3 8.3 11.1 13.9 23.5 11.3 17.5 8.6 5.7 13.1 3.1 10.9 10.6 7.8 11.6 9.0 9.5 9.9 17.7 3.5 2.8 13.7 6.2 2.4 9.5 2.8 3.3 2.9 3.0 7.2 3.7 3.0 2.3 41.0 2.8 7.9 3.0 3.5 7.1 8.1 7.9 7.7 9.0 7.6 7.2 8.1 6.7 7.4 8.4 11.9 9.1 36.6 70.2 172.6 16.8 82.7 20.4 12.0 15.9 26.2 17.7 26.7 64.6 55.7 3.4 26.3 20.4 0.0 37.1 42.2 48.3 73.3 23.0 12.3 68.9 15.9 39.9 20.3 88.9 2.2 30.8 81.6 50.6 49.5 35.6 15.8 57.2 16.4 30.4 41.3 13.7 6.5 58.7 28.6 16.0 166.2 124.6 28.7 24.7 105.6 UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628433 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.14e-1)" "unprognostic (2.75e-3)" "prognostic favorable (5.09e-5)" "prognostic favorable (5.90e-4)" "unprognostic (2.33e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (9.63e-7)" "unprognostic (7.41e-3)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (1.41e-3)" "prognostic unfavorable (2.09e-5)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.20e-1)" "unprognostic (1.07e-1)" 35.6 25.0 41.2 31.5 39.9 44.2 35.9 31.9 49.6 43.9 50.4 35.5 31.5 22.2 35.5 52.2 44.8 47.6 27.1 34.8 39.5 40.5 37.2 39.5 34.8 55.6 40.5 36.1 35.3 41.7 23.8 35.3 33.6 35.9 30.8 46.4 30.7 30.5 37.9 80.6 33.2 37.4 39.3 41.9 41.3 29.1 68.0 29.3 71.0 34.4 31.2 64.5 42.2 36.1 34.3 39.3 40.8 23.0 22.5 41.7 19.5 34.1 22.8 40.0 27.9 27.0 34.7 25.6 36.1 33.8 42.6 49.9 58.6 32.5 48.8 47.6 37.2 52.7 21.7 39.2 60.9 57.1 31.5 22.9 27.7 25.2 33.7 52.9 27.0 24.7 27.2 31.5 42.3 63.3 36.9 45.4 32.3 24.0 41.8 39.5 34.3 41.6 38.5 22.0 12.0 24.8 31.8 41.6 35.3 44.8 40.4 36.5 24.1 31.5 40.6 57.4 89.9 25.4 24.0 29.7 32.6 18.1 27.0 44.1 30.1 48.9 68.5 23.3 44.6 25.9 14.8 20.9 40.8 22.6 18.8 24.7 34.1 32.7 31.7 23.4 34.3 41.7 35.2 34.5 22.5 23.0 39.3 40.0 19.5 41.2 39.9 31.9 49.6 39.5 40.5 40.5 36.1 35.9 29.3 29.8 71.1 173.0 150.9 152.6 68.0 80.9 79.0 36.1 43.3 64.6 76.6 160.4 182.4 173.6 500.3 117.4 113.7 70.0 156.3 191.8 125.8 164.5 136.2 71.0 157.1 89.0 118.5 93.9 121.3 409.1 96.7 157.7 145.1 191.2 112.3 128.4 182.8 103.7 88.1 147.6 99.0 116.4 156.8 337.7 125.2 178.2 208.7 191.8 148.1 221.1 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 67.2 70.6 39.1 52.7 44.6 132.7 70.4 36.9 50.9 45.5 51.8 37.5 38.4 49.3 46.3 39.1 63.2 45.7 47.5 72.5 37.3 39.5 63.0 91.9 67.5 68.1 43.4 36.9 60.6 53.4 42.8 49.1 66.5 45.2 49.6 48.5 38.4 46.7 43.3 91.1 53.2 58.9 48.4 44.4 68.2 49.5 40.0 42.2 88.8 66.3 55.4 61.4 74.6 81.4 24.7 31.2 118.0 36.2 29.7 33.2 50.9 53.5 30.7 51.2 41.3 54.7 79.0 44.0 54.5 72.7 48.7 46.0 46.0 76.5 57.4 35.7 55.3 63.2 30.7 54.6 73.2 67.1 53.2 27.5 52.2 31.6 37.5 57.4 73.4 45.0 59.9 46.4 53.7 75.3 63.0 63.1 47.3 65.6 58.7 64.8 43.2 107.7 41.8 37.1 61.3 30.7 56.8 50.3 41.4 49.1 51.2 51.8 43.6 33.5 86.1 61.5 63.1 35.7 43.4 57.9 51.0 43.6 33.3 49.5 52.0 67.0 87.8 54.3 40.9 54.7 71.1 35.9 54.6 25.1 36.1 33.2 24.7 31.8 29.6 31.2 20.1 32.6 29.7 118.0 29.7 36.2 21.5 32.6 50.9 39.1 44.6 36.9 50.9 37.3 39.5 43.4 36.9 45.2 42.2 154.9 181.2 227.9 605.7 749.7 127.0 210.7 150.3 190.1 129.7 132.6 117.8 279.1 464.2 286.3 668.3 228.0 265.9 93.5 333.2 474.9 260.0 477.5 219.4 203.4 354.6 116.0 231.0 159.0 357.1 423.2 152.5 359.3 339.1 356.1 198.5 111.8 351.4 245.4 140.0 328.0 157.1 103.5 376.3 128.5 151.0 711.0 533.9 297.5 192.3 680.6 UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926438-43956136 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 48.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 25.3" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (9.95e-3)" "unprognostic (6.76e-2)" "unprognostic (6.87e-2)" "unprognostic (8.94e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.58e-3)" "unprognostic (4.74e-2)" "unprognostic (5.04e-2)" "prognostic favorable (4.86e-4)" "prognostic favorable (5.77e-4)" "prognostic favorable (6.51e-4)" "unprognostic (1.11e-1)" "unprognostic (8.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.34e-1)" 10.1 13.1 14.7 5.0 13.3 4.5 9.1 13.8 17.4 8.8 7.6 11.4 7.9 5.3 7.5 11.2 8.0 9.0 7.2 23.8 14.2 10.0 12.7 15.3 8.4 5.3 12.1 9.4 7.9 17.4 8.7 6.9 5.9 11.9 8.7 6.2 8.1 10.6 9.1 48.6 9.4 5.3 10.3 12.8 7.3 6.5 5.1 6.1 2.7 9.6 16.1 5.7 7.7 6.5 10.7 11.8 12.9 20.5 7.7 14.0 6.7 3.8 3.2 2.0 9.1 9.4 3.8 1.5 1.9 4.7 2.4 3.2 1.7 4.6 3.7 5.3 5.0 6.8 4.4 2.5 2.1 3.7 8.3 4.2 4.0 5.0 4.4 3.5 8.7 8.2 2.9 4.4 2.7 4.2 3.5 3.0 4.6 4.4 7.8 3.3 2.5 5.1 5.0 4.4 4.7 4.2 3.2 2.8 5.8 5.1 4.7 7.4 25.3 4.0 8.1 3.0 3.8 4.0 2.6 2.6 1.6 5.1 3.4 5.5 11.2 8.4 1.8 4.8 11.4 8.9 6.3 11.7 12.9 9.3 18.4 9.5 10.3 11.6 10.5 11.8 10.7 14.0 11.5 1.1 7.7 20.5 10.2 9.4 6.7 14.7 13.3 13.8 17.4 14.2 10.0 12.1 9.4 11.9 6.1 0.0 6.2 8.8 8.1 5.6 8.3 21.8 5.1 2.7 6.8 15.7 2.0 9.7 46.4 15.9 5.0 11.9 8.4 0.0 24.7 17.3 10.8 9.8 4.6 22.2 24.7 11.1 18.0 9.2 7.3 8.0 11.2 12.9 15.1 24.4 7.1 9.1 14.6 5.8 20.5 38.0 10.4 6.5 12.0 15.1 8.3 9.8 6.4 6.9 7.9 9.3 UBE2E1 UbcH6 ENSG00000170142 "Ubiquitin conjugating enzyme E2 E1" P51965 3 23805903-23891316 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030445, CAB073413" Approved Approved Nucleoplasm NA NA Nucleoplasm "CAB073413: , HPA030445: AB_10669599" "unprognostic (7.50e-2)" "unprognostic (2.78e-2)" "unprognostic (7.91e-3)" "unprognostic (7.13e-2)" "unprognostic (6.74e-3)" "unprognostic (1.74e-1)" "prognostic unfavorable (9.97e-7)" "unprognostic (3.69e-2)" "unprognostic (3.53e-2)" "unprognostic (1.34e-2)" "unprognostic (5.36e-3)" "unprognostic (2.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.94e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" 32.0 28.1 50.8 34.7 44.4 56.1 52.6 38.7 43.4 41.9 40.6 32.4 27.5 23.9 35.3 35.6 57.9 29.5 29.9 58.5 47.3 43.2 33.6 34.0 34.9 44.9 52.0 36.9 36.5 32.0 41.6 22.5 44.5 38.1 38.5 37.8 23.2 30.3 36.4 52.2 33.3 25.8 44.1 55.6 36.3 29.9 24.3 43.3 33.8 41.4 38.0 47.3 52.2 46.3 6.7 7.6 6.8 9.1 7.0 7.2 4.1 33.9 21.4 33.7 16.8 20.6 30.1 29.5 25.7 40.0 28.9 38.8 16.1 37.6 30.1 21.8 24.8 24.6 11.0 39.8 31.8 37.9 36.3 44.5 41.5 16.1 19.6 29.7 40.9 22.1 28.4 30.0 36.8 49.5 34.0 45.9 21.1 29.0 33.5 23.1 17.5 28.7 44.5 49.5 18.7 54.9 32.0 14.8 86.5 45.0 24.3 9.8 35.1 23.0 21.4 37.0 35.2 24.0 54.1 29.8 21.2 26.3 15.7 19.1 28.0 16.5 59.5 22.9 39.3 16.4 2.4 8.4 6.8 4.5 9.1 6.5 6.5 5.4 3.8 7.3 6.7 7.2 4.3 3.3 7.0 5.8 7.6 3.9 4.1 50.8 44.4 38.7 43.4 47.3 43.2 52.0 36.9 38.1 43.3 41.7 28.2 30.6 52.3 64.2 26.4 54.9 28.1 46.8 28.4 17.4 3.9 83.0 48.0 80.0 20.6 53.7 35.4 0.0 68.5 82.1 57.3 58.6 40.3 19.1 88.2 19.1 44.5 42.4 63.6 39.3 37.7 75.5 92.8 111.0 36.1 49.9 62.2 59.6 45.6 32.6 20.9 51.8 80.2 36.3 62.2 78.9 60.3 35.4 44.6 59.6 UBE2E2 "FLJ25157, UbcH8" ENSG00000182247 "Ubiquitin conjugating enzyme E2 E2" Q96LR5 3 23203020-23591793 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.2;intermediate monocyte: 17.8;memory B-cell: 12.3;myeloid DC: 20.9;naive B-cell: 14.8;non-classical monocyte: 18.3;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 6 "B-cells: 14.8;dendritic cells: 27.1;monocytes: 18.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA028872, HPA030445, CAB073417" Approved Approved Nucleoplasm No No Nucleoplasm "CAB073417: , HPA003303: AB_1858521, HPA028872: AB_10966277, HPA030445: AB_10669599" "unprognostic (2.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-2)" "unprognostic (3.68e-3)" "unprognostic (3.74e-2)" "unprognostic (1.70e-1)" "unprognostic (9.19e-3)" "unprognostic (3.11e-3)" "unprognostic (1.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.20e-1)" "unprognostic (4.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.44e-2)" "unprognostic (2.68e-2)" "unprognostic (3.11e-2)" "unprognostic (6.11e-3)" 22.7 11.4 19.2 12.0 23.3 7.6 15.9 18.8 32.7 22.4 14.5 20.8 7.5 5.9 17.7 31.9 19.7 12.0 18.5 23.4 21.3 21.8 19.1 15.8 16.7 17.7 14.1 19.7 19.0 9.8 15.5 14.4 9.0 20.9 18.2 6.4 8.4 11.2 17.0 32.0 14.8 7.2 22.4 17.6 15.9 11.1 17.8 13.3 14.8 16.8 11.1 14.5 17.0 16.2 14.8 27.1 0.4 18.3 0.8 3.6 5.2 17.1 6.2 16.3 0.3 14.5 16.2 14.8 10.8 18.5 10.2 14.4 1.7 14.1 14.9 7.5 9.5 14.1 1.7 11.8 16.9 13.2 0.1 11.9 0.0 7.3 2.0 10.4 0.0 12.0 12.8 17.8 14.7 24.8 10.5 9.8 11.8 0.8 15.9 9.2 2.7 7.8 3.3 11.6 9.8 9.0 16.4 6.3 17.1 10.0 0.4 4.2 8.7 11.9 7.0 0.2 12.3 15.0 9.9 8.5 10.1 14.3 6.7 12.2 15.3 5.0 22.0 9.5 6.7 2.8 0.0 15.2 0.0 0.2 17.8 0.3 12.3 0.5 0.2 20.9 14.8 3.6 1.3 0.4 0.8 18.3 27.1 0.2 5.2 19.2 23.3 18.8 32.7 21.3 21.8 14.1 19.7 20.9 13.3 20.8 9.8 36.3 10.5 22.8 22.7 32.7 20.4 5.3 4.5 29.6 15.7 28.0 58.0 12.3 17.6 20.4 0.0 0.0 25.6 33.5 29.3 47.2 0.0 38.4 44.7 30.2 1.7 14.7 43.5 12.0 36.5 55.4 74.2 35.1 0.7 10.9 13.5 0.3 49.8 98.2 2.9 32.3 50.9 33.5 99.2 36.9 32.3 2.5 0.5 5.1 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 115.4" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved NA NA "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.08e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 29.1 23.9 35.6 21.1 33.0 20.1 49.7 37.4 62.9 30.4 25.2 18.6 19.8 23.0 26.6 29.2 23.1 29.7 35.9 37.8 43.9 32.5 36.0 29.6 28.5 37.6 31.5 31.9 27.7 29.9 42.9 21.6 23.9 30.5 20.9 27.8 24.6 26.3 22.7 76.8 28.1 26.2 24.1 41.3 20.4 28.3 28.1 21.5 30.9 37.4 27.8 23.0 31.8 23.0 7.7 29.7 25.6 16.9 8.5 12.0 9.6 17.6 8.1 115.4 4.0 34.3 44.3 18.4 23.7 30.0 20.0 25.0 8.7 21.5 8.7 20.8 32.3 16.8 7.6 69.6 24.3 36.0 21.2 21.0 30.1 10.9 24.1 16.5 13.9 14.4 17.4 22.7 17.5 16.9 20.4 26.3 18.3 15.3 16.3 49.0 9.7 25.3 13.1 22.0 12.1 38.2 24.8 11.8 20.7 34.0 15.6 20.1 22.5 10.3 11.0 9.7 33.0 5.9 20.7 24.2 39.0 25.7 22.8 27.5 14.3 9.1 24.5 38.4 5.5 21.6 13.0 14.0 25.6 9.3 12.3 11.1 7.7 7.3 12.0 9.2 4.9 7.8 8.5 13.2 8.5 16.9 29.7 2.8 9.6 35.6 33.0 37.4 62.9 43.9 32.5 31.5 31.9 30.5 21.5 8.9 21.6 43.9 66.6 91.4 128.2 30.3 89.2 34.8 33.0 52.4 27.5 34.3 193.9 78.5 28.7 62.5 41.0 70.0 89.6 68.0 102.0 68.5 23.1 44.5 72.1 71.5 57.4 65.7 57.3 50.1 58.1 56.9 123.2 35.1 42.3 53.3 82.5 28.1 33.9 136.3 56.9 25.8 51.2 91.9 204.0 107.0 30.1 59.0 46.5 88.8 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Extravillous trophoblasts: 231.1;monocytes: 312.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037444 Approved Approved Cytosol NA NA Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 14.5 18.4 21.3 13.6 17.6 19.9 17.2 12.2 19.8 16.7 15.8 17.7 12.3 13.6 14.7 32.2 25.0 11.0 16.3 34.6 20.2 21.6 14.6 24.1 12.9 26.4 23.4 10.1 10.4 62.8 16.3 13.2 22.2 24.2 14.9 19.6 11.4 15.3 18.2 32.1 10.3 17.9 20.2 20.2 14.6 15.1 13.9 16.8 15.8 32.9 17.4 17.7 18.7 16.4 10.9 23.1 35.6 30.0 39.9 29.1 24.6 13.5 7.7 17.8 18.2 23.2 28.3 25.2 12.7 18.3 14.4 14.8 8.4 8.7 7.0 4.6 28.5 31.4 11.5 20.1 27.7 22.6 10.6 7.8 9.6 9.8 27.4 29.2 4.0 22.7 16.2 45.8 19.0 29.0 13.4 25.5 33.0 29.3 4.5 26.0 20.3 10.9 17.7 19.6 19.5 11.8 13.3 11.8 12.4 21.7 5.7 11.9 17.8 14.9 11.3 23.6 31.2 10.2 16.8 15.8 15.9 14.0 18.0 13.6 5.6 4.3 13.7 18.8 12.2 11.7 35.6 21.0 25.2 29.1 27.6 11.5 10.9 19.9 17.6 18.6 10.1 18.6 18.8 15.6 39.9 30.0 23.1 20.5 24.6 21.3 17.6 12.2 19.8 20.2 21.6 23.4 10.1 24.2 16.8 6.0 20.2 41.4 18.8 28.8 21.7 44.5 28.1 24.1 5.7 26.2 7.9 72.4 48.0 42.5 17.3 25.5 37.0 70.0 68.9 231.1 37.6 41.8 20.8 40.0 129.2 25.4 40.1 23.9 54.8 47.2 23.9 61.5 33.7 312.0 46.7 15.8 69.1 29.2 29.0 52.2 19.3 38.8 35.6 90.0 52.7 35.3 54.9 47.3 30.7 31.1 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.6" "Cell type enhanced" "Detected in many" 6 "Basal keratinocytes: 254.1;Suprabasal keratinocytes: 209.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA045681: AB_2679417, HPA050551: AB_2681171" "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 10.8 11.1 12.6 17.8 13.5 14.3 11.2 11.6 15.3 13.0 19.4 17.8 8.9 11.9 13.3 8.5 27.4 9.2 9.7 26.9 13.5 11.2 14.6 17.7 8.9 18.7 15.2 9.7 9.1 17.1 12.0 6.0 11.4 14.5 14.0 13.3 8.8 11.9 12.0 95.6 14.1 16.6 14.6 19.4 15.0 11.9 11.8 13.6 21.3 12.5 20.7 23.3 17.7 16.5 23.7 13.1 24.4 11.5 20.5 20.6 13.1 21.2 23.1 21.6 15.8 17.7 18.7 30.8 20.8 16.7 19.8 17.5 15.9 10.9 33.4 21.8 20.4 16.2 23.1 26.8 19.3 32.0 17.5 21.8 12.5 12.3 18.1 17.4 18.1 23.7 15.9 28.9 18.8 27.4 14.0 26.5 22.5 21.8 36.2 16.3 9.5 23.0 16.6 23.8 15.8 12.0 29.9 11.4 30.5 23.1 14.0 9.3 17.4 19.6 17.1 16.1 33.3 16.7 11.9 19.8 19.9 15.2 23.3 23.2 14.1 16.5 47.2 15.3 17.0 15.3 8.1 10.3 24.4 15.4 10.8 20.6 23.7 20.1 20.1 13.1 15.5 20.2 20.5 18.6 20.5 11.5 9.6 18.3 13.1 12.6 13.5 11.6 15.3 13.5 11.2 15.2 9.7 14.5 13.6 20.8 11.8 63.6 34.1 254.1 16.5 62.6 30.6 13.4 13.6 24.4 5.9 36.7 69.6 27.6 105.5 28.7 35.4 0.0 23.2 45.9 34.4 47.3 20.7 52.9 41.3 14.3 36.9 32.5 36.1 173.0 18.1 34.1 64.1 33.3 32.7 23.0 32.9 27.5 19.8 61.3 13.9 6.5 47.9 63.9 47.7 209.5 55.8 43.3 26.8 53.3 UBE2G2 UBC7 ENSG00000184787 "Ubiquitin conjugating enzyme E2 G2" P60604 21 44768580-44802019 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003332 Approved NA NA "HPA003332: AB_1858525" "unprognostic (7.58e-2)" "unprognostic (5.41e-2)" "unprognostic (1.58e-2)" "unprognostic (4.45e-2)" "unprognostic (6.30e-2)" "unprognostic (4.67e-2)" "unprognostic (5.99e-2)" "unprognostic (3.79e-3)" "unprognostic (6.93e-3)" "unprognostic (7.02e-2)" "unprognostic (1.40e-2)" "unprognostic (6.98e-3)" "prognostic unfavorable (7.02e-5)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.55e-2)" 30.9 20.7 18.9 22.8 20.9 25.8 21.1 21.0 21.6 18.9 22.7 20.5 19.8 14.9 22.2 18.4 19.3 20.5 18.0 37.1 18.3 17.1 26.2 27.3 19.7 19.7 19.0 17.0 18.1 30.2 22.1 26.0 17.0 18.9 18.3 16.5 18.6 15.4 28.3 50.8 15.6 16.9 28.5 17.8 23.8 20.2 14.0 18.8 18.4 20.6 18.7 21.6 20.9 18.9 11.9 17.5 5.9 13.0 14.0 17.3 12.1 15.8 3.3 10.9 14.1 15.0 6.5 10.0 11.2 8.7 9.8 10.7 12.6 2.1 20.5 10.8 11.1 12.8 6.4 16.0 13.5 8.9 19.2 16.5 33.4 2.3 10.1 11.9 24.6 5.7 10.6 16.0 13.1 12.8 4.3 15.4 23.2 31.0 14.3 13.5 7.1 27.2 2.9 28.4 11.0 14.2 22.3 10.1 18.4 12.8 8.5 12.7 22.7 15.8 5.1 16.1 10.5 5.0 21.4 10.9 9.5 6.8 8.8 18.1 22.5 44.3 20.3 9.5 29.1 11.2 2.3 11.6 5.9 16.0 11.8 17.3 11.8 14.7 16.2 12.5 11.9 15.7 16.6 3.6 14.0 13.0 17.5 14.6 12.1 18.9 20.9 21.0 19.3 18.3 17.1 19.0 17.0 18.9 18.8 53.6 111.1 38.9 31.3 42.4 53.2 62.9 33.1 54.9 61.4 50.6 62.8 35.1 21.6 28.3 52.3 44.9 23.7 0.0 34.6 19.9 31.7 31.1 41.7 58.7 31.0 30.2 28.8 38.1 32.5 135.1 38.3 37.1 27.0 32.5 25.2 36.8 34.2 17.3 47.4 29.6 96.5 25.8 32.3 26.1 49.0 48.9 30.0 30.5 38.7 35.8 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952949 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 29.0 49.9 31.1 16.6 31.0 22.5 24.5 36.1 30.2 31.1 27.3 33.2 26.6 15.2 35.5 25.3 32.1 29.4 26.6 61.0 26.4 25.4 27.6 28.1 26.3 17.5 28.1 23.4 27.6 52.3 41.8 29.5 37.9 33.3 24.1 16.8 22.9 28.5 28.8 46.3 21.3 16.5 31.5 26.2 19.1 22.7 24.7 29.5 24.7 37.7 23.6 29.5 25.5 34.3 6.1 3.7 7.8 2.2 1.3 6.5 1.9 22.1 12.0 14.3 14.5 35.4 30.5 24.7 20.5 26.5 12.6 14.1 6.4 23.8 9.2 25.7 20.2 32.6 16.9 12.2 21.8 16.5 11.3 6.5 3.2 17.7 7.7 27.9 6.3 10.1 41.0 29.0 17.0 27.3 28.0 24.5 9.8 7.5 26.7 19.4 7.9 8.4 6.9 22.4 15.1 14.3 6.6 7.3 19.6 26.3 29.1 5.4 16.5 18.8 42.1 11.0 44.9 4.4 6.2 24.8 13.7 6.9 19.3 20.4 24.4 17.5 15.2 27.3 7.6 13.3 3.5 2.2 5.1 4.7 1.7 6.4 3.8 4.7 4.2 2.0 6.1 6.0 6.4 7.8 1.3 2.1 3.7 6.5 1.9 31.1 31.0 36.1 30.2 26.4 25.4 28.1 23.4 33.3 29.5 38.7 38.0 39.2 140.7 129.5 52.7 101.3 53.5 54.9 53.4 68.0 56.9 93.6 34.9 51.9 67.1 55.4 27.8 116.8 62.1 57.4 57.8 206.4 14.9 63.8 35.3 41.3 56.6 44.8 35.5 35.6 40.9 28.3 45.5 12.6 27.9 82.0 95.7 31.7 73.9 39.7 32.0 12.9 55.1 22.7 17.7 134.4 167.6 24.9 23.0 232.4 UBE2I UBC9 ENSG00000103275 "Ubiquitin conjugating enzyme E2 I" P63279 16 1308880-1327018 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003909, CAB009021" Approved NA NA 120000 "CAB009021: AB_2210610, HPA003909: AB_1858529" "unprognostic (2.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.55e-2)" "unprognostic (3.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.88e-3)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (7.60e-3)" "unprognostic (3.56e-1)" "unprognostic (7.28e-2)" "unprognostic (9.30e-2)" "unprognostic (1.57e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.15e-3)" 34.3 43.1 28.8 36.3 36.9 48.4 45.2 45.6 48.5 38.1 32.0 28.6 28.1 28.9 55.4 32.9 43.4 35.6 30.3 41.8 27.4 28.4 29.4 26.6 29.1 44.2 22.7 32.9 62.5 35.5 33.4 36.2 47.2 21.4 40.7 31.0 34.1 37.8 32.2 31.6 35.8 32.2 40.0 23.2 43.7 29.4 43.6 21.6 78.0 42.5 31.8 53.9 38.7 38.8 82.2 58.0 85.4 67.4 50.9 57.8 60.0 25.5 35.2 59.5 35.0 25.5 30.9 25.7 36.8 26.6 34.3 34.2 41.7 42.0 44.5 30.6 31.7 31.2 31.1 42.5 34.6 44.2 31.9 30.0 27.8 32.6 40.2 40.4 41.2 33.2 28.6 22.4 33.6 40.1 33.3 37.0 37.0 39.8 28.0 32.3 54.4 72.7 41.5 48.4 28.9 26.1 92.4 37.7 50.5 31.9 23.5 33.7 35.6 32.3 36.7 36.6 35.5 37.3 50.0 30.5 34.0 39.0 29.8 33.2 29.6 35.0 90.7 19.1 30.6 36.0 63.9 59.3 85.4 48.0 67.4 57.8 82.2 49.0 48.7 58.0 61.8 44.1 44.2 41.3 50.9 62.3 50.1 50.9 60.0 28.8 36.9 45.6 48.5 27.4 28.4 22.7 32.9 21.4 21.6 47.6 65.0 161.9 150.2 158.7 57.7 79.1 79.0 46.8 86.4 59.3 47.1 272.2 89.5 194.9 43.7 106.6 69.9 46.7 129.2 244.2 135.3 169.8 105.3 33.7 188.2 44.5 98.2 78.5 89.4 24.8 120.3 128.8 121.4 250.7 90.2 79.4 176.3 97.7 101.1 89.7 59.4 77.6 104.9 123.1 163.1 180.8 349.7 134.6 123.3 223.4 UBE2J1 "CGI-76, HSPC153, NCUBE1, UBC6" ENSG00000198833 "Ubiquitin conjugating enzyme E2 J1" Q9Y385 6 89326625-89352848 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 501.0;Late spermatids: 1092.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 63.8;Karpas-707: 55.2;U-266/70: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003509, CAB073419" Enhanced NA NA "CAB073419: , HPA003509: AB_1858531" "unprognostic (1.82e-1)" "unprognostic (3.20e-2)" "unprognostic (1.55e-3)" "prognostic favorable (2.87e-4)" "unprognostic (3.41e-1)" "unprognostic (7.93e-3)" "prognostic unfavorable (6.90e-5)" "unprognostic (1.19e-1)" "unprognostic (9.36e-2)" "prognostic favorable (7.43e-4)" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.11e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (9.38e-2)" 18.7 17.3 14.6 47.1 15.4 52.7 28.2 19.1 13.6 18.8 25.9 11.3 24.4 28.0 19.5 18.4 19.2 18.0 19.9 17.1 14.4 14.7 18.7 33.5 20.4 52.0 17.0 9.5 17.2 46.1 11.5 13.6 27.5 13.0 22.9 26.3 10.7 42.1 33.2 12.5 11.3 36.3 17.9 18.9 45.8 24.4 17.7 14.4 42.5 17.6 16.4 47.7 21.7 21.4 20.7 23.7 15.9 17.8 6.4 6.4 6.1 8.3 2.9 8.1 10.3 8.5 11.1 0.0 13.3 11.8 8.2 9.1 4.7 5.2 63.8 7.4 13.7 6.9 3.4 5.3 7.7 13.5 8.9 8.2 11.6 3.8 7.7 22.6 14.5 7.6 8.4 7.7 6.9 11.8 11.1 18.4 7.6 9.3 55.2 9.6 5.1 6.0 11.2 2.8 5.9 4.2 23.9 10.5 30.5 10.3 5.9 4.1 8.3 5.6 12.4 12.3 12.3 4.9 32.3 12.3 4.6 4.4 8.1 10.2 62.1 30.8 17.5 9.1 10.5 7.6 10.3 6.6 12.3 3.4 11.1 4.0 20.7 4.6 4.2 6.5 13.4 4.3 3.9 15.9 6.4 17.8 23.7 6.4 6.1 14.6 15.4 19.1 13.6 14.4 14.7 17.0 9.5 13.0 14.4 14.9 33.4 95.3 52.5 22.0 31.9 8.1 30.6 22.7 18.2 19.2 27.5 69.3 43.1 55.4 501.0 59.9 55.1 0.0 88.1 72.0 50.7 96.3 24.3 37.6 70.2 22.3 74.2 98.8 102.2 1092.2 50.6 55.8 69.2 46.9 54.1 14.7 86.7 70.2 44.9 36.1 13.7 32.3 55.6 20.7 19.6 30.4 108.2 36.2 57.4 100.2 UBE2J2 "NCUBE2, Ubc6p" ENSG00000160087 "Ubiquitin conjugating enzyme E2 J2" Q8N2K1 1 1253909-1273885 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 350.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.25e-1)" "unprognostic (3.04e-2)" "unprognostic (1.88e-2)" "unprognostic (4.46e-2)" "unprognostic (1.67e-3)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (9.57e-2)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (2.09e-2)" "unprognostic (6.19e-2)" "unprognostic (1.87e-1)" "unprognostic (3.46e-2)" 24.4 22.2 17.5 21.6 17.1 19.4 33.0 23.8 24.9 17.8 22.0 17.9 19.9 22.0 22.9 21.4 25.2 21.8 20.7 21.2 17.5 17.1 21.6 27.3 17.4 27.4 15.9 15.4 19.4 36.3 14.4 22.8 22.6 15.9 16.9 16.2 18.7 24.2 20.2 29.8 23.2 23.6 19.3 13.1 25.2 22.2 68.3 12.8 26.1 22.8 21.7 23.8 18.3 19.3 24.5 22.3 39.6 23.0 22.0 25.3 17.7 25.7 10.7 15.3 14.6 12.4 12.8 11.9 19.9 15.8 27.2 19.9 19.0 18.8 13.9 21.3 18.4 15.0 18.8 15.5 19.8 21.7 23.5 27.8 20.9 21.0 17.1 24.1 19.1 20.1 12.0 11.1 21.3 15.9 14.9 19.1 19.0 28.8 13.8 15.7 12.8 27.7 21.5 16.5 17.0 26.9 25.8 14.2 22.9 14.1 8.7 56.4 27.9 13.7 29.6 31.4 14.5 15.2 21.8 15.6 16.5 15.8 19.1 20.3 30.4 29.5 38.8 21.2 30.4 13.0 38.2 23.0 39.6 22.0 22.2 20.1 24.5 23.4 22.8 22.3 21.7 21.2 20.9 32.6 22.0 21.3 20.8 25.3 17.7 17.5 17.1 23.8 24.9 17.5 17.1 15.9 15.4 15.9 12.8 8.9 15.9 25.3 40.7 37.9 27.4 16.7 33.1 6.7 21.6 27.9 7.9 59.9 48.0 58.6 187.2 33.6 39.3 0.0 81.4 63.5 40.5 45.1 16.1 24.1 46.5 22.3 16.8 23.9 23.0 350.9 34.8 33.1 38.8 45.1 36.5 29.9 79.3 31.6 35.3 57.4 25.4 32.3 40.3 121.4 83.7 38.1 73.0 44.7 38.2 51.2 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698044-39782792 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Approved "Plasma membrane,Cytosol" NA NA 150000 Cytosol "Plasma membrane" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 27.2 21.8 27.0 21.2 27.6 17.3 21.6 38.6 40.7 17.0 33.2 11.8 14.1 29.1 19.9 18.5 29.9 14.9 18.5 28.1 27.7 26.8 26.6 44.5 17.1 17.9 24.1 26.4 16.9 15.8 18.9 26.9 29.8 25.2 19.7 24.0 13.4 18.4 17.3 31.8 22.0 24.6 18.8 19.2 16.9 29.3 16.0 15.9 21.3 23.6 19.7 18.8 22.8 20.4 17.6 23.7 20.6 19.9 10.9 14.1 8.9 24.2 24.9 13.4 12.7 8.4 7.9 22.8 33.4 7.1 9.0 9.4 37.6 25.0 30.3 29.4 9.4 22.1 10.2 25.8 14.6 14.4 20.3 18.5 39.2 25.2 32.5 10.6 42.1 22.2 7.4 16.5 12.6 13.6 9.4 11.7 13.3 39.8 10.9 9.2 23.5 29.3 23.4 17.8 14.0 19.0 17.3 40.3 11.3 12.5 33.8 27.9 12.3 25.0 9.5 14.9 15.5 12.2 14.1 32.0 14.0 29.7 16.6 30.7 15.4 45.0 33.3 7.3 27.0 16.4 13.9 16.6 20.6 13.5 14.3 12.7 17.6 14.1 12.6 16.6 12.5 10.7 12.0 13.3 10.9 19.9 23.7 13.7 8.9 27.0 27.6 38.6 37.7 27.7 26.8 24.1 26.4 25.2 15.9 53.6 50.8 35.6 49.5 109.2 60.1 57.3 45.9 71.0 67.1 47.1 27.5 74.8 56.3 76.3 97.5 58.3 92.6 70.0 77.7 144.5 61.6 76.6 33.5 101.0 71.4 98.5 57.3 61.4 71.5 150.7 60.4 73.4 54.0 103.6 63.5 70.2 109.4 73.0 53.0 81.7 38.2 38.8 67.9 71.4 46.9 120.6 123.3 48.4 65.5 98.3 UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 110.3" "HPA045609, HPA062415" Approved Approved Nucleoplasm,Cytosol NA NA 8800000 "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: AB_2684756" "unprognostic (4.90e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.99e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "prognostic favorable (3.82e-6)" "unprognostic (3.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.18e-2)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.77e-1)" "unprognostic (3.15e-3)" 27.8 34.9 34.8 23.5 29.6 31.3 24.9 25.5 36.9 25.9 27.7 38.4 22.8 26.4 25.6 29.2 38.0 26.9 23.0 33.0 30.7 30.8 27.4 36.0 23.5 32.5 34.3 33.1 24.3 23.9 24.3 21.7 30.1 36.9 27.5 31.7 29.3 30.6 26.7 43.5 23.9 34.4 33.1 36.2 28.5 25.1 35.7 22.6 25.3 25.0 32.4 33.9 28.4 22.2 34.7 49.9 46.1 45.8 34.6 46.9 54.9 24.9 14.4 21.1 16.5 23.1 20.7 12.2 21.1 24.1 27.1 25.8 16.4 12.1 23.6 10.6 27.9 20.5 21.4 28.1 22.9 27.1 23.5 30.4 27.3 14.1 19.5 15.4 39.0 19.7 18.2 20.0 19.7 14.3 19.6 30.4 14.7 110.3 12.7 29.3 18.4 20.2 28.2 15.5 28.0 15.2 16.6 31.8 6.4 25.4 20.1 19.0 14.1 16.8 21.2 19.4 20.3 13.2 21.6 21.8 19.3 24.8 16.2 21.4 12.4 20.0 21.6 26.1 18.1 18.2 30.8 40.4 46.1 41.4 45.8 38.8 34.7 39.6 44.2 49.9 31.2 34.5 41.6 34.2 34.6 37.6 48.4 46.9 54.9 34.8 29.6 25.5 36.9 30.7 30.8 34.3 33.1 36.9 22.6 101.3 71.0 116.9 138.6 111.5 51.2 50.6 107.0 125.8 95.5 68.0 15.7 283.0 167.5 270.4 53.8 105.0 174.1 140.2 335.7 335.1 102.8 131.4 126.9 137.0 262.0 65.2 120.8 104.3 125.9 41.0 80.8 163.0 119.8 326.4 95.3 76.6 339.4 136.8 97.6 204.5 41.2 103.5 83.5 134.5 117.6 113.3 311.1 142.4 115.8 190.0 UBE2L6 UBCH8 ENSG00000156587 "Ubiquitin conjugating enzyme E2 L6" O14933 11 57551656-57568284 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Hofbauer cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003328, CAB073407" Enhanced Approved Cytosol NA NA 34000 Cytosol "CAB073407: , HPA003328: AB_1858539" "prognostic favorable (6.75e-4)" "unprognostic (2.10e-2)" "unprognostic (1.09e-2)" "unprognostic (2.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (3.13e-2)" "unprognostic (4.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.88e-4)" "unprognostic (3.07e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" "unprognostic (6.42e-2)" 31.1 31.0 32.0 34.1 28.6 30.4 40.4 18.2 25.6 23.3 19.1 17.0 17.1 19.0 21.9 30.0 19.9 28.6 27.4 18.4 23.5 27.4 28.3 55.1 50.5 45.0 28.9 20.4 27.1 21.8 17.9 18.5 21.7 25.8 26.0 18.8 18.7 42.8 22.2 10.1 15.9 23.5 28.3 23.6 47.9 21.4 7.7 23.6 44.0 33.6 15.1 34.4 33.0 49.0 49.2 53.6 113.6 83.4 61.2 66.4 112.6 8.7 4.4 15.0 4.7 31.7 39.5 1.6 5.1 30.5 45.2 58.9 1.6 22.8 28.1 18.1 15.5 39.1 7.0 6.4 16.8 9.6 25.5 0.2 27.6 0.0 6.3 58.7 6.3 9.2 42.2 3.9 21.2 5.8 16.8 14.2 29.7 1.2 19.5 8.1 11.1 42.6 15.3 3.9 0.0 5.6 37.7 9.1 19.2 12.1 9.8 0.3 7.8 10.2 0.8 22.4 2.7 11.2 3.2 5.2 9.4 3.3 7.1 1.6 26.6 26.8 0.5 26.4 16.0 2.0 56.7 71.6 62.5 51.2 83.4 56.4 49.2 53.4 53.4 53.6 39.7 46.5 48.8 113.6 61.2 68.3 34.0 66.4 112.6 32.0 28.6 18.2 25.6 23.5 27.4 28.9 20.4 25.8 23.6 26.8 17.4 54.4 23.2 20.7 10.2 5.2 28.1 24.1 27.3 12.2 3.9 3.0 54.7 68.9 3.6 46.7 22.7 23.3 57.3 31.0 37.7 34.1 53.1 27.3 148.0 12.7 23.0 41.1 54.9 9.6 44.5 69.1 8.5 44.1 29.8 31.5 45.0 31.7 31.5 19.8 3.9 25.8 41.2 1.9 6.0 24.2 2.9 74.7 21.7 24.6 UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558960 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 134.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: AB_436983, HPA054551: AB_2682520, HPA057800: AB_2683531" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-3)" "unprognostic (3.90e-3)" "unprognostic (4.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (8.63e-3)" "unprognostic (1.76e-1)" "unprognostic (5.85e-2)" "unprognostic (8.42e-3)" 18.1 26.0 51.8 16.3 38.9 32.1 13.6 28.4 52.4 15.2 20.4 17.0 20.5 17.8 17.3 19.6 24.9 19.3 17.4 43.2 35.1 33.9 19.6 19.1 16.5 18.1 32.1 30.5 19.4 20.2 25.9 22.8 32.0 26.4 18.4 16.7 15.0 20.9 22.6 61.9 19.2 15.9 19.2 19.8 18.5 17.9 31.8 16.1 32.7 22.2 21.2 19.9 18.2 23.5 3.8 7.6 10.9 4.3 1.8 3.8 2.1 21.5 39.3 19.9 18.9 10.6 12.7 14.5 22.5 19.8 16.3 14.1 23.7 16.8 22.7 17.0 15.9 32.7 14.1 22.1 22.2 12.3 25.8 134.3 33.0 25.3 15.4 26.0 29.8 26.2 13.6 17.4 24.8 29.5 17.9 19.6 21.5 16.0 28.7 21.6 22.1 23.8 27.1 12.6 25.2 34.4 22.2 16.6 29.2 18.8 27.2 35.1 28.7 19.5 23.9 21.0 7.6 14.3 27.4 14.6 51.1 10.4 16.0 39.8 34.8 52.5 24.3 32.5 26.5 33.3 6.8 4.3 4.1 3.5 2.8 2.7 3.4 3.8 3.7 3.1 3.8 3.7 2.5 10.9 1.8 2.7 7.6 3.1 2.1 51.8 38.9 28.4 52.4 35.1 33.9 32.1 30.5 26.4 16.1 6.0 15.4 10.4 28.7 35.8 101.5 34.7 17.8 12.0 6.8 17.4 19.6 18.8 6.6 15.3 18.8 19.0 45.1 23.3 26.0 17.2 20.9 42.6 19.6 28.7 30.5 103.3 39.5 20.3 27.6 27.8 16.1 18.1 33.7 11.8 28.6 85.9 31.9 25.4 13.1 25.9 58.3 25.8 25.5 26.4 7.9 49.7 43.8 15.2 31.9 47.5 UBE2N "MGC8489, UBC13, UbcH-ben" ENSG00000177889 "Ubiquitin conjugating enzyme E2 N" P61088 12 93405673-93442262 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 15 "Early spermatids: 2177.0;Late spermatids: 6552.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044976 Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 4600000 Nucleoplasm "Nucleoli fibrillar center" "HPA044976: AB_2679163" "unprognostic (1.74e-2)" "unprognostic (5.53e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (8.09e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (8.49e-3)" "unprognostic (2.72e-1)" "unprognostic (4.28e-3)" "unprognostic (1.07e-1)" "unprognostic (9.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (1.30e-3)" 24.7 25.0 29.0 28.7 39.1 29.0 21.2 29.2 44.3 18.4 26.6 15.6 15.1 20.7 23.2 20.0 30.4 19.7 17.0 27.7 31.0 33.7 25.4 22.3 19.3 36.1 27.6 34.5 17.4 17.6 13.9 18.2 24.2 34.9 23.4 22.6 13.7 18.0 18.5 35.7 19.1 20.4 21.3 24.6 21.5 19.3 83.7 17.4 32.2 15.5 16.8 35.1 22.7 18.8 53.8 35.5 29.9 39.2 29.5 57.3 51.9 36.5 26.5 44.7 28.6 17.3 17.2 31.2 51.1 27.3 41.1 34.5 47.1 15.9 74.4 11.6 29.9 27.2 29.1 49.3 37.5 39.2 61.9 25.6 50.0 14.6 41.5 22.2 59.7 33.4 18.0 15.5 24.5 30.6 29.2 31.6 29.2 55.6 11.6 42.6 30.0 59.0 55.6 58.2 32.3 37.1 45.9 36.3 36.4 34.2 55.3 43.8 39.9 27.0 31.8 25.0 25.2 41.6 36.8 32.6 27.9 23.3 25.0 36.8 20.0 54.3 63.2 10.9 31.9 33.9 29.9 27.1 28.9 31.7 35.4 36.9 53.8 40.2 39.2 35.5 38.6 36.0 34.4 8.2 29.5 39.2 26.7 57.3 51.9 29.0 39.1 29.2 44.3 31.0 33.7 27.6 34.5 34.9 17.4 35.7 44.5 137.9 175.3 286.2 65.4 70.5 33.1 62.9 66.0 85.5 25.5 212.3 162.5 138.2 2177.0 83.9 61.7 70.0 87.1 187.9 124.3 118.3 92.3 44.8 144.3 82.6 71.7 46.1 58.9 6552.8 86.9 108.4 140.0 201.0 50.2 87.6 106.5 77.7 80.9 127.4 40.9 45.3 165.8 246.5 216.4 281.9 238.1 122.0 65.5 190.8 UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389451-76453206 "Enzymes, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Bipolar cells: 42.3;Horizontal cells: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" No No 1600000 Nucleoplasm "Nuclear bodies" "HPA023605: AB_2671257" "unprognostic (8.75e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (8.68e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (6.84e-8)" "unprognostic (3.54e-1)" "unprognostic (2.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.34e-9)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" 8.5 8.5 13.8 10.2 22.6 19.2 7.3 25.2 38.1 9.4 7.2 12.2 7.4 9.9 9.9 8.2 11.7 10.8 7.1 15.4 12.7 15.2 6.5 7.6 6.6 12.8 11.7 14.6 13.9 14.4 16.4 14.3 9.8 30.6 9.4 6.0 10.5 13.4 10.4 23.0 15.2 8.2 8.0 8.0 10.8 10.8 18.1 12.2 10.9 15.8 6.9 9.2 8.6 9.1 4.9 4.1 2.7 1.7 1.5 4.0 1.9 13.1 15.1 15.5 19.0 9.7 6.2 13.4 6.2 6.7 10.1 9.9 13.1 6.7 18.7 4.4 7.7 15.9 13.4 18.0 10.7 7.2 5.3 22.2 18.9 9.9 21.9 8.0 11.4 11.5 6.3 8.7 9.6 8.3 8.8 13.6 10.4 15.7 16.7 5.1 10.8 22.5 13.2 14.3 7.9 20.3 22.3 20.0 20.6 4.5 11.3 23.0 20.7 9.0 23.6 12.4 14.8 13.5 8.2 8.0 11.9 11.2 10.0 10.2 13.8 4.5 15.8 13.0 9.6 7.7 0.0 1.7 2.7 4.0 0.8 2.2 2.6 2.6 2.0 1.0 4.9 2.1 3.0 0.4 1.5 1.0 4.1 2.3 1.9 13.8 22.6 25.2 38.1 12.7 15.2 11.7 14.6 30.6 12.2 3.0 7.7 17.1 5.1 7.7 42.3 23.4 7.6 4.0 6.8 7.0 39.3 5.0 0.0 5.2 1.1 7.5 4.7 0.0 8.0 6.4 7.7 7.2 6.9 5.0 7.0 42.9 22.4 8.6 7.9 1.1 8.9 3.9 5.0 9.0 8.7 8.2 6.5 7.0 7.4 3.1 23.7 6.5 10.0 16.6 18.4 10.8 4.3 6.4 7.9 4.8 UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063368 Approved Approved Nucleoplasm,Centrosome No No Nucleoplasm Centrosome "HPA063368: AB_2684996" "unprognostic (3.88e-1)" "unprognostic (2.13e-1)" "unprognostic (4.44e-3)" "unprognostic (3.64e-3)" "unprognostic (5.32e-3)" "unprognostic (6.10e-3)" "prognostic unfavorable (8.74e-4)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (9.92e-3)" "unprognostic (3.79e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.84e-7)" "unprognostic (2.20e-1)" "unprognostic (4.46e-1)" "prognostic favorable (1.86e-5)" "unprognostic (1.04e-2)" 17.3 18.7 26.5 16.2 29.4 24.2 19.4 26.4 29.0 20.0 21.2 18.7 8.2 16.2 18.3 25.4 20.9 21.8 18.2 17.6 24.5 25.8 25.7 27.4 23.0 26.3 22.8 21.0 21.7 27.2 21.4 29.3 24.5 27.2 21.4 25.7 18.5 19.0 19.8 19.1 21.6 21.4 21.9 19.1 26.0 20.5 30.0 22.0 25.1 21.0 14.0 29.9 19.3 18.5 3.2 5.1 8.1 3.1 4.7 6.2 1.6 17.2 14.9 21.1 16.1 21.7 22.4 18.3 17.1 26.0 22.0 17.8 16.7 18.4 21.2 24.6 23.8 18.4 15.0 24.8 19.8 19.0 21.3 15.7 16.8 13.3 16.1 27.4 27.3 27.1 21.5 26.3 17.8 20.7 24.0 28.2 19.7 14.1 26.3 28.1 26.7 16.6 20.1 28.8 41.3 25.4 19.2 14.7 22.3 24.2 18.3 21.5 30.1 17.3 32.6 27.9 37.7 19.9 41.7 19.6 14.3 15.9 16.9 18.2 32.2 23.8 28.1 16.0 19.4 21.5 8.1 2.8 5.6 4.8 3.1 4.3 3.0 4.5 5.9 2.5 3.2 5.0 5.7 4.4 4.7 2.6 5.1 6.2 1.6 26.5 29.4 26.4 29.0 24.5 25.8 22.8 21.0 27.2 22.0 29.8 21.6 22.7 16.5 14.3 38.7 26.9 25.5 34.8 20.5 15.7 3.9 15.3 10.0 13.0 2.7 27.8 23.7 0.0 18.0 14.1 15.8 22.6 10.4 34.2 23.2 57.2 32.3 32.5 41.4 4.3 16.4 19.3 13.5 15.4 30.4 45.6 21.9 11.5 18.0 15.1 19.3 12.9 13.2 30.7 24.4 16.7 16.4 20.8 20.4 22.9 UBE2Q2 DKFZp762C143 ENSG00000140367 "Ubiquitin conjugating enzyme E2 Q2" Q8WVN8 15 75843285-75901078 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Rod photoreceptor cells: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "unprognostic (1.28e-1)" "unprognostic (1.66e-2)" "unprognostic (2.45e-2)" "unprognostic (4.28e-2)" "unprognostic (8.82e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-3)" "unprognostic (1.32e-1)" "unprognostic (6.38e-2)" "prognostic favorable (5.73e-4)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (1.47e-3)" "unprognostic (1.01e-3)" "unprognostic (1.92e-1)" "unprognostic (1.69e-2)" "unprognostic (5.92e-2)" 17.8 19.8 15.6 18.8 10.9 22.2 41.1 11.6 14.4 20.0 25.2 12.4 12.9 6.0 17.6 15.5 24.7 11.8 22.7 25.1 15.0 16.0 16.5 6.3 21.0 25.9 19.8 10.3 17.2 13.8 7.7 12.6 34.8 12.0 22.3 13.5 13.0 20.1 15.0 26.4 11.0 11.1 42.9 23.1 15.1 14.7 13.5 11.6 27.6 21.4 22.3 11.2 40.2 35.7 6.1 4.2 18.0 6.9 10.6 9.6 4.8 9.6 14.8 13.8 9.8 19.3 25.5 20.7 21.4 24.2 14.2 16.2 7.7 13.3 9.6 15.9 30.7 12.7 7.9 24.7 14.1 17.5 9.8 10.0 12.0 9.0 10.4 21.3 12.5 7.0 17.7 16.4 10.0 14.8 21.2 19.6 17.4 4.5 14.5 30.1 7.4 10.2 11.6 9.7 1.5 10.7 12.2 21.6 3.8 22.6 15.4 12.0 9.4 18.4 17.3 23.3 20.6 11.1 17.2 25.9 17.7 16.2 11.8 7.5 15.8 27.7 7.6 7.1 19.3 10.7 18.0 4.7 15.5 7.2 5.3 9.0 6.1 9.6 7.6 4.2 4.8 7.7 6.4 0.7 10.6 6.9 1.5 6.1 4.8 15.6 10.9 11.6 14.4 15.0 16.0 19.8 10.3 12.0 11.6 3.0 9.2 13.9 24.8 44.8 18.2 27.1 17.8 2.7 17.0 22.7 127.6 47.1 19.9 22.6 48.2 37.3 1.6 23.3 14.7 102.2 32.0 46.6 19.7 3.8 22.3 6.4 17.9 28.3 25.4 26.7 22.5 34.8 35.4 26.2 21.3 14.6 20.4 10.5 27.3 24.5 151.5 25.8 46.7 48.6 74.1 40.7 92.0 27.7 17.9 30.6 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448623-6494909 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 28.1;heart muscle: 11.3;retina: 8.2;seminal vesicle: 8.6;skeletal muscle: 21.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 23.6;Cardiomyocytes: 25.0;Horizontal cells: 42.9;Rod photoreceptor cells: 49.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "eosinophil: 1.2" "Lineage enhanced" "Detected in single" "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "Karpas-707: 18.2;PC-3: 15.2;SCLC-21H: 14.2;U-266/70: 34.1;U-266/84: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 0.6 2.3 8.6 0.8 4.2 0.3 0.9 20.7 28.1 1.0 1.8 1.0 0.5 0.7 1.4 1.8 1.0 0.5 0.8 11.3 12.6 8.2 2.6 1.1 0.4 0.7 5.2 4.6 3.6 0.8 0.3 1.3 0.3 8.7 3.1 0.8 8.2 1.0 8.6 21.3 2.4 1.0 1.3 1.4 0.4 2.2 0.9 0.0 0.0 1.9 2.0 0.5 0.5 0.9 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.2 0.0 3.1 0.0 0.0 0.2 0.0 15.2 0.1 0.0 6.7 0.0 0.0 14.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 34.1 30.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 4.2 20.7 19.4 12.6 8.2 5.2 4.6 8.7 0.0 0.0 0.0 0.0 0.6 1.1 23.6 25.0 0.0 0.0 0.0 0.0 5.9 0.0 5.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.5 0.7 0.0 0.8 0.1 42.9 5.2 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.0 8.4 0.2 0.0 6.3 0.0 49.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817567-33920404 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Early spermatids: 295.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 21.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061000, HPA074334" Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Nucleoli" Cytosol "HPA061000: AB_2684408, HPA074334: " "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (7.08e-2)" "unprognostic (1.53e-1)" "unprognostic (6.55e-2)" "unprognostic (5.15e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.82e-3)" "unprognostic (4.61e-3)" "unprognostic (3.05e-3)" "unprognostic (2.22e-2)" "unprognostic (4.19e-1)" "unprognostic (2.01e-2)" "unprognostic (4.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.43e-1)" 26.1 19.7 29.4 19.7 26.8 13.9 39.3 23.7 32.3 25.6 24.1 27.9 16.3 28.0 26.1 18.4 25.3 22.3 21.8 29.2 25.5 20.3 22.1 34.5 23.0 27.1 30.5 23.2 29.8 44.5 15.7 13.9 24.6 21.6 21.0 21.4 19.3 18.7 20.8 56.1 28.1 25.7 28.5 24.2 21.6 20.8 34.5 29.6 36.7 19.5 22.5 25.7 35.8 30.5 3.3 4.2 21.9 11.6 5.0 2.1 2.4 16.5 18.1 35.0 15.2 19.3 31.5 10.8 14.7 20.5 17.3 17.3 14.5 12.4 14.1 6.0 20.5 12.6 7.4 18.3 16.8 19.0 23.2 9.7 12.2 20.0 18.4 27.5 14.4 13.3 26.7 25.0 14.1 26.8 27.7 29.0 17.0 11.4 15.2 17.1 9.6 27.1 38.0 19.9 14.2 15.1 25.3 10.6 7.3 18.3 12.5 16.4 19.7 17.2 15.4 11.0 23.2 13.5 17.6 21.7 16.7 15.2 11.5 13.6 9.7 9.1 19.8 15.9 8.4 35.9 12.4 7.5 4.1 2.0 7.5 1.3 3.1 1.9 1.6 4.2 3.3 1.9 1.7 21.9 5.0 11.6 2.6 2.1 2.4 29.4 26.8 23.7 32.3 25.5 20.3 30.5 23.2 21.6 29.6 20.8 30.7 29.5 39.6 93.8 61.0 106.8 56.0 22.7 25.0 21.0 13.7 52.6 13.3 43.8 295.7 77.1 60.6 23.3 59.7 65.2 54.0 68.4 12.7 72.1 68.5 57.2 69.2 77.3 105.2 195.4 62.2 81.9 33.7 49.5 57.3 87.1 69.4 38.6 71.5 49.6 30.1 58.2 41.9 90.2 66.2 105.3 69.2 30.5 49.0 79.7 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407777 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0;lymphoid tissue: 60.2;testis: 69.4" "Cell type enhanced" "Detected in many" 4 "Extravillous trophoblasts: 226.9;Spermatocytes: 216.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: AB_2683351" "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 10.2 9.2 18.0 19.5 15.9 68.0 4.7 11.4 21.6 6.1 12.0 9.1 4.5 8.4 7.1 7.2 17.1 6.0 9.7 18.0 18.7 18.1 5.9 5.6 6.3 22.9 13.7 14.4 6.4 6.0 3.7 12.9 9.8 12.9 7.0 7.1 6.2 4.9 5.3 7.3 6.2 7.3 10.7 15.3 11.0 10.6 69.4 8.2 60.2 5.9 14.3 21.1 10.0 7.1 4.5 3.1 6.0 1.9 0.6 2.6 0.3 60.3 32.7 28.8 22.9 1.8 2.6 5.1 49.2 14.9 30.4 27.7 22.1 21.6 58.8 20.4 12.3 36.6 17.8 28.8 12.8 13.5 46.0 95.7 35.1 18.8 7.1 5.5 42.0 34.2 2.9 3.6 22.3 21.6 6.6 11.9 32.1 34.9 41.2 19.0 16.0 56.8 21.8 72.2 16.9 55.5 50.1 22.2 21.1 8.1 12.9 73.1 39.6 62.7 15.6 27.9 9.1 11.1 22.8 18.2 18.3 52.1 15.6 116.9 33.2 79.7 69.0 19.2 29.7 66.3 1.1 1.9 2.9 1.8 1.5 1.2 4.5 2.6 2.6 1.5 1.6 2.5 1.5 6.0 0.6 0.9 3.1 1.0 0.3 18.0 15.9 11.4 21.6 18.7 18.1 13.7 14.4 12.9 8.2 0.0 4.3 37.3 136.4 144.5 56.5 2.4 7.6 0.0 0.0 19.2 51.1 34.3 13.3 44.4 86.7 31.2 25.8 70.0 26.4 226.9 94.9 63.2 18.4 9.6 55.5 30.2 88.9 22.7 24.7 27.7 16.1 39.9 70.9 55.1 28.4 76.7 57.6 28.1 11.7 14.8 59.0 12.9 96.6 216.2 140.8 101.4 50.0 44.7 30.4 121.0 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease mutation, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.8" "Cell type enhanced" "Detected in many" 12 "Erythroid cells: 186.9;Extravillous trophoblasts: 82.9;Spermatocytes: 115.5;Spermatogonia: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favorable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 1.9 4.2 9.6 8.5 12.2 20.8 3.9 4.4 13.5 3.5 11.2 0.7 17.2 7.5 4.3 4.1 10.3 2.9 3.0 8.8 8.8 11.2 4.5 2.8 3.1 15.2 8.7 8.2 1.3 0.9 2.4 3.1 8.7 8.2 2.2 13.9 1.9 2.8 7.0 13.1 4.5 6.9 8.1 3.4 6.7 4.0 16.0 1.8 46.8 2.6 12.8 15.3 6.3 4.5 9.0 3.6 1.7 8.6 1.1 11.1 2.9 30.4 29.1 43.3 20.4 4.0 7.4 24.8 33.3 18.6 38.1 26.9 20.7 37.4 35.5 13.2 12.1 28.4 24.9 40.0 19.5 34.4 32.2 22.9 21.7 15.8 23.6 1.8 25.9 26.4 2.6 4.7 29.9 12.5 9.1 22.1 40.1 27.3 29.3 29.8 28.3 46.4 33.1 16.8 31.7 14.8 36.0 46.1 30.8 14.6 14.6 34.1 34.8 23.3 28.7 11.1 13.5 30.2 16.4 10.8 17.2 27.5 30.0 39.5 14.9 29.1 45.2 17.0 27.0 35.6 0.0 0.8 1.7 3.7 2.4 2.8 9.0 5.0 3.9 1.7 6.3 7.3 8.0 0.0 1.1 8.6 3.6 11.1 2.9 9.6 12.2 4.4 13.5 8.8 11.2 8.7 8.2 8.2 1.8 0.0 2.1 10.4 11.0 12.7 5.2 12.2 0.0 6.7 7.9 5.2 0.0 33.9 5.0 11.2 13.0 1.9 2.7 186.9 6.6 82.9 4.8 2.2 8.1 1.7 23.5 9.5 1.2 4.3 1.8 6.6 2.8 5.2 3.3 3.6 9.0 1.3 7.8 0.0 3.9 7.9 0.9 6.5 1.9 115.5 96.9 9.5 18.8 9.5 19.6 4.1 UBE2U MGC35130 ENSG00000177414 "Ubiquitin conjugating enzyme E2 U (putative)" Q5VVX9 1 64203627-64267368 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 31.8" "Group enriched" "Detected in some" 12 "Early spermatids: 118.4;Late spermatids: 169.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.4;U-266/84: 1.3" "Region enhanced" "Detected in many" "midbrain: 19.5" NA NA "unprognostic (9.44e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-1)" "unprognostic (4.01e-2)" "unprognostic (3.63e-1)" "unprognostic (7.69e-2)" 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.7 118.4 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 169.4 1.7 0.0 0.0 1.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.0 11.9 1.8 0.0 0.2 0.0 0.0 0.0 UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli NA NA Nucleoli "HPA045161: AB_10960706, HPA073181: AB_2686578" "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-3)" "unprognostic (3.17e-1)" "unprognostic (9.74e-2)" "unprognostic (3.09e-2)" "unprognostic (6.93e-3)" "unprognostic (1.83e-1)" "unprognostic (3.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" "unprognostic (5.01e-2)" "unprognostic (4.38e-2)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" 15.2 14.2 13.5 13.3 21.8 17.5 13.4 18.9 24.4 12.0 9.8 11.3 11.0 7.9 13.4 10.5 16.6 9.4 15.2 14.8 19.0 12.3 21.9 23.4 13.6 11.6 11.6 13.0 11.8 12.7 18.4 20.9 13.6 18.4 12.0 11.5 9.5 12.2 10.6 16.4 10.6 8.5 12.8 12.6 13.6 10.0 16.4 12.3 14.7 17.1 4.8 12.9 16.8 12.8 5.0 8.1 23.0 9.4 4.7 4.3 4.8 8.6 5.7 7.0 7.5 12.2 12.5 6.1 9.5 10.5 9.2 9.6 4.7 9.7 4.0 7.9 9.9 14.0 8.8 10.2 9.7 15.3 6.5 6.2 8.1 5.9 7.2 8.2 4.5 11.6 9.8 10.9 10.7 19.2 8.3 11.1 4.5 4.0 8.6 13.9 6.9 9.7 4.8 5.3 12.3 11.2 2.9 7.1 3.4 17.0 9.5 5.2 5.7 7.6 24.7 11.4 7.9 11.5 8.0 9.9 11.1 8.4 8.4 6.9 7.3 7.5 3.0 9.7 7.1 9.5 12.9 9.4 11.5 3.5 8.8 4.3 5.0 3.6 2.6 6.3 4.3 3.2 3.8 23.0 4.7 9.4 8.1 4.0 4.8 13.5 21.8 18.9 24.4 19.0 12.3 11.6 13.0 18.4 12.3 14.9 12.3 22.7 24.3 49.1 33.4 20.4 20.4 9.4 11.4 50.6 15.7 15.8 43.1 21.3 107.9 29.2 13.4 116.8 15.1 16.5 23.4 29.3 20.7 25.1 35.4 39.7 22.3 20.3 43.6 45.7 19.0 46.1 40.5 76.7 12.2 23.6 17.3 14.0 17.7 41.3 27.1 19.4 60.9 31.4 29.8 56.3 46.1 34.9 12.5 36.9 UBE2Z "FLJ13855, USE1" ENSG00000159202 "Ubiquitin conjugating enzyme E2 Z" Q9H832 17 48908369-48929056 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007922 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA007922: AB_1858551" "unprognostic (6.85e-2)" "unprognostic (5.72e-3)" "prognostic favorable (4.62e-4)" "unprognostic (9.11e-2)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.32e-2)" "unprognostic (5.26e-2)" "unprognostic (8.66e-2)" "unprognostic (9.17e-3)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (2.63e-2)" "unprognostic (2.11e-2)" "unprognostic (1.91e-2)" "unprognostic (1.52e-1)" 27.1 40.6 29.2 27.7 37.0 22.2 28.8 34.4 50.2 33.7 28.9 59.9 45.1 26.6 36.2 49.5 37.2 36.0 28.0 28.7 30.5 29.2 32.1 25.6 29.2 30.9 46.6 28.0 32.5 29.5 36.6 28.0 35.0 39.7 32.9 32.5 28.4 33.3 43.2 24.1 35.9 30.5 39.1 32.7 36.6 29.4 22.4 43.4 29.4 39.8 22.2 44.2 28.8 32.2 12.8 10.1 11.0 14.5 7.4 13.1 8.6 24.9 30.9 11.6 11.0 29.6 28.8 15.9 27.3 33.5 32.8 31.6 38.5 21.6 20.3 39.2 33.5 41.2 16.2 14.6 25.5 41.9 67.1 15.8 18.4 20.5 23.9 34.2 13.0 19.8 24.5 28.3 26.7 34.6 35.1 24.0 9.7 13.4 26.5 35.1 39.8 14.0 12.9 10.8 30.5 27.1 11.3 29.6 11.5 25.6 24.6 12.0 18.2 18.5 10.0 18.6 27.4 27.6 10.3 28.1 49.0 23.7 16.0 22.2 20.2 19.2 12.0 24.0 9.6 21.2 6.5 11.0 8.1 13.1 14.5 10.7 9.4 11.4 13.0 8.0 12.8 11.1 12.0 11.0 7.4 13.0 10.1 11.5 8.6 29.2 37.0 34.4 50.2 30.5 29.2 46.6 28.0 39.7 43.4 23.8 16.3 32.1 40.1 46.9 52.1 29.9 30.6 18.7 10.3 34.9 39.3 29.1 18.3 38.9 1.4 40.2 31.5 0.0 46.7 25.9 26.8 61.1 5.8 22.9 22.6 41.3 46.7 39.9 23.9 2.9 25.9 27.7 28.7 52.3 35.4 30.6 59.6 28.1 27.3 20.7 33.6 32.3 35.3 21.4 22.7 49.8 35.8 22.3 24.7 60.4 UBE3A "ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A" ENSG00000114062 "Ubiquitin protein ligase E3A" Q05086 15 25333728-25439056 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009723, HPA039410, HPA040380" Approved Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB009723: AB_639982, HPA039410: AB_10671997, HPA040380: AB_2676952" "unprognostic (7.95e-2)" "unprognostic (2.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.99e-1)" "unprognostic (1.13e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-1)" "unprognostic (3.05e-1)" "unprognostic (5.07e-2)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (4.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (8.17e-2)" 19.3 19.4 20.3 23.1 25.0 17.8 20.2 30.0 25.1 21.7 19.9 14.3 19.8 14.1 21.0 22.1 19.8 18.5 17.2 24.0 22.2 20.8 20.2 24.6 19.7 23.1 19.1 19.5 23.0 17.2 26.1 24.6 20.1 20.9 20.6 17.9 13.3 19.3 21.5 70.2 18.4 18.8 21.2 19.9 18.8 16.9 26.4 16.4 36.4 25.0 26.6 19.5 19.9 26.6 15.6 11.9 11.6 14.8 21.1 16.0 5.7 19.6 11.1 28.1 16.7 16.4 19.5 13.8 30.3 19.0 21.5 19.6 25.7 9.8 35.4 23.0 22.6 21.2 18.2 35.5 21.4 26.3 18.2 11.9 29.3 18.8 15.2 24.7 35.3 21.7 23.1 20.1 20.3 26.0 22.4 16.9 31.1 29.5 25.3 33.7 10.7 29.3 10.3 18.2 21.5 16.2 30.0 42.0 15.6 19.5 31.0 28.9 21.8 24.6 26.7 34.9 19.0 21.8 20.0 21.6 37.7 31.2 18.1 22.1 28.9 34.1 47.7 21.6 19.3 19.6 8.6 8.7 11.6 13.3 7.6 15.2 12.0 14.0 15.9 11.9 15.6 16.0 14.2 2.0 21.1 14.8 11.1 10.1 5.7 20.3 25.0 30.0 25.1 22.2 20.8 19.1 19.5 20.9 16.4 89.3 73.3 52.7 60.3 63.2 78.1 154.5 43.3 71.0 67.1 36.6 53.0 43.4 16.6 42.2 101.1 45.8 39.4 0.0 43.1 41.8 44.5 85.9 62.2 52.0 41.5 76.3 65.9 47.3 56.6 43.8 52.6 44.6 50.6 37.9 48.7 54.8 47.5 42.1 60.8 44.0 56.4 77.6 54.5 143.0 88.7 79.3 61.9 44.9 47.9 87.8 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 14.5 19.3 17.2 12.9 21.2 9.2 15.3 19.7 27.8 14.4 17.3 23.3 14.0 14.6 17.4 16.2 20.1 19.3 13.9 28.6 14.6 11.6 19.8 16.4 15.5 13.1 18.6 13.9 18.4 20.3 25.5 15.1 16.8 15.8 17.5 21.2 20.7 15.7 17.4 34.0 21.6 16.3 18.6 15.2 17.0 17.3 24.5 18.3 18.2 21.1 17.6 15.9 19.5 19.6 15.9 14.5 22.4 16.7 14.3 18.2 11.4 10.4 16.5 13.0 9.4 22.2 17.9 11.4 13.8 15.8 16.8 11.3 17.3 10.7 6.5 10.3 22.6 14.3 13.5 13.1 17.7 16.2 14.3 9.3 12.4 10.8 15.6 14.2 10.1 10.4 20.3 16.5 16.2 19.5 25.4 18.1 15.5 13.6 6.2 19.1 16.3 6.9 14.8 13.3 11.7 19.9 11.5 12.2 12.7 14.4 18.8 12.1 22.4 16.1 21.9 10.7 15.9 22.4 10.8 16.5 20.8 6.0 10.6 9.8 13.9 11.5 11.5 20.7 8.5 17.2 22.4 15.3 14.3 15.9 16.7 15.7 15.9 15.3 11.2 14.5 12.9 12.9 17.1 19.5 14.3 13.6 13.5 18.2 11.4 17.2 21.2 19.7 27.8 14.6 11.6 18.6 13.9 15.8 18.3 11.9 10.8 6.7 10.0 4.5 20.4 32.1 10.2 14.7 14.8 15.7 31.4 15.7 10.0 16.0 11.8 13.5 15.1 23.3 13.2 9.3 8.4 15.1 9.2 16.0 11.1 20.6 8.6 12.9 17.1 24.6 11.5 11.0 10.1 14.4 15.8 16.7 18.8 10.5 9.2 17.7 25.0 6.5 8.5 9.6 12.7 6.4 19.8 10.9 13.8 12.2 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138913-157269372 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favorable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 24.7 21.0 14.0 17.9 23.1 12.4 19.8 25.5 29.9 21.3 23.4 17.2 15.3 17.4 28.8 16.8 26.8 18.8 24.8 31.8 14.4 13.8 21.2 30.5 16.7 16.7 14.5 15.1 20.7 22.1 29.6 20.3 21.3 22.3 19.0 21.0 20.2 31.7 21.5 51.2 21.2 23.9 25.7 16.1 20.5 21.8 35.9 11.1 20.3 15.6 24.5 24.4 23.1 19.1 2.5 4.0 2.1 4.6 3.7 6.6 2.9 22.8 18.2 11.7 23.3 21.0 22.1 12.9 25.3 21.9 21.4 21.7 16.3 19.1 12.4 22.5 27.9 27.9 14.5 18.1 23.3 25.4 22.5 16.6 12.6 12.7 11.7 20.9 18.8 18.5 19.5 21.6 23.7 19.7 16.3 24.9 10.4 18.3 13.8 30.2 20.0 18.4 11.9 18.5 20.5 21.9 10.6 13.1 25.4 22.1 25.2 18.7 19.3 24.9 21.5 18.5 13.6 11.1 13.2 22.3 27.0 5.8 66.1 31.3 13.9 13.9 12.5 31.0 28.1 30.8 0.5 3.5 2.1 4.8 4.6 6.6 2.5 5.2 5.2 4.0 2.5 4.9 5.9 1.3 3.7 4.5 3.6 5.2 2.9 14.0 23.1 25.5 29.9 14.4 13.8 14.5 15.1 22.3 11.1 20.8 19.5 9.7 13.9 24.5 31.4 31.5 28.1 16.0 9.1 24.4 62.8 12.2 8.3 17.0 8.4 19.9 22.1 0.0 15.2 14.4 14.7 19.9 9.2 39.2 13.9 30.2 23.5 24.5 21.2 8.5 14.4 15.0 5.0 12.6 20.6 10.9 22.5 10.5 24.1 16.5 42.8 0.0 17.6 20.4 27.4 29.1 12.6 13.8 22.4 27.3 UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359585-118399211 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055035, HPA064010" Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA055035: AB_2682679, HPA064010: AB_2685174" "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" 19.3 18.5 17.7 20.5 30.1 16.6 19.7 49.4 36.6 19.0 18.5 33.0 16.1 20.3 23.2 21.2 21.2 19.8 17.0 20.3 17.7 18.8 20.3 29.5 18.4 22.2 25.7 25.7 24.2 26.7 31.1 24.2 18.6 35.5 21.5 23.1 21.2 20.3 17.2 32.5 25.6 23.7 19.9 25.5 24.0 25.5 21.8 27.5 22.1 22.1 15.1 22.6 21.6 20.4 5.7 11.0 14.6 13.2 7.1 9.0 5.2 9.3 9.1 11.7 11.6 20.3 18.8 11.6 13.9 14.5 10.3 12.6 25.1 23.0 19.7 26.8 17.4 13.9 20.7 16.4 13.1 17.2 11.1 7.6 32.3 8.1 12.8 17.5 18.2 24.8 18.9 9.5 21.1 20.7 13.8 17.1 17.4 18.3 18.6 14.8 17.6 15.5 18.2 10.8 18.9 11.7 9.9 16.9 20.1 11.3 21.9 10.6 11.1 20.0 17.4 6.1 13.3 23.2 8.3 17.6 15.3 10.1 13.0 11.5 5.5 6.7 18.8 8.5 21.1 15.7 14.6 10.9 10.5 9.0 12.0 6.9 5.7 6.9 6.4 11.0 4.3 7.4 6.6 11.0 7.1 13.2 6.5 7.7 5.2 17.7 30.1 49.4 36.6 17.7 18.8 25.7 25.7 35.5 27.5 11.9 26.4 13.7 19.3 23.8 18.0 14.9 15.3 37.5 22.7 14.0 17.7 16.7 5.0 16.7 12.4 18.0 17.7 23.3 24.6 14.8 17.7 22.8 10.4 40.3 19.1 15.9 17.9 20.3 28.8 11.0 15.8 24.1 23.6 16.2 19.6 21.4 21.8 17.5 20.1 10.2 16.0 19.4 18.4 31.7 19.8 34.4 20.7 21.8 19.8 23.0 UBE4B "E4, KIAA0684, UBOX3, UFD2" ENSG00000130939 "Ubiquitination factor E4B" O95155 1 10032832-10181239 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019219 Approved NA NA "HPA019219: AB_1858554" "unprognostic (5.32e-2)" "unprognostic (1.56e-1)" "unprognostic (3.74e-2)" "unprognostic (5.46e-2)" "unprognostic (7.19e-2)" "unprognostic (4.39e-2)" "prognostic unfavorable (3.69e-5)" "unprognostic (2.53e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-1)" "unprognostic (4.26e-1)" "unprognostic (3.10e-1)" "unprognostic (1.86e-3)" "unprognostic (2.99e-1)" "unprognostic (3.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-3)" 11.8 18.6 16.4 11.5 20.2 16.5 12.7 27.1 24.2 17.5 19.3 26.5 12.6 15.1 16.7 12.8 20.4 14.1 11.3 22.5 18.9 17.3 13.0 13.9 10.5 11.3 18.5 15.0 22.8 20.4 24.3 15.3 18.3 23.6 14.5 12.8 18.2 12.0 12.7 43.5 24.3 14.5 16.6 16.3 13.0 15.1 8.6 21.4 15.7 19.7 11.2 13.6 16.8 12.0 6.0 6.7 9.4 7.9 2.9 9.8 5.3 21.7 13.9 17.1 18.9 22.8 30.1 13.5 14.3 18.1 14.0 14.5 15.0 25.4 18.7 17.4 25.4 11.1 16.1 21.5 16.5 16.7 19.1 12.0 20.2 24.3 17.6 17.3 21.0 14.4 24.7 15.0 18.9 16.1 26.6 20.7 13.7 34.5 24.9 13.0 11.3 13.5 10.3 22.9 14.1 11.6 13.3 17.0 20.1 14.2 9.9 21.0 16.1 22.5 16.1 29.7 19.1 12.3 15.5 17.8 12.6 19.5 15.5 11.7 11.4 15.4 21.7 18.5 24.4 15.9 4.2 7.9 3.6 5.3 6.0 8.8 6.0 8.8 8.5 6.7 5.6 8.0 6.5 9.4 2.9 4.4 3.2 9.8 5.3 16.4 20.2 27.1 24.2 18.9 17.3 18.5 15.0 23.6 21.4 20.8 20.0 17.1 11.5 15.7 13.3 33.5 15.3 13.4 11.4 8.7 23.6 28.0 8.3 10.9 2.4 13.5 13.1 23.3 12.7 11.4 17.5 19.5 5.8 15.3 14.9 15.9 15.6 16.5 22.1 3.1 10.3 14.2 5.0 9.0 16.9 11.3 18.3 13.9 8.1 8.6 34.6 19.4 11.2 6.6 12.4 19.6 17.2 13.1 17.9 12.2 UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263081-159286040 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039615 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA039615: AB_10674425" "unprognostic (1.25e-1)" "unprognostic (3.10e-1)" "unprognostic (6.04e-3)" "unprognostic (3.45e-2)" "unprognostic (7.08e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (4.46e-5)" "unprognostic (4.01e-1)" "unprognostic (2.14e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (2.51e-2)" 17.1 16.0 16.7 18.4 19.7 16.7 16.3 20.2 33.0 18.5 12.5 12.2 11.4 9.8 22.5 13.1 22.2 14.7 14.5 13.1 20.9 19.1 17.5 14.4 17.8 24.1 19.7 22.7 16.8 12.6 18.0 23.9 19.6 36.7 14.7 14.7 10.9 15.4 17.6 15.3 14.2 13.8 19.5 20.4 22.2 13.3 24.2 15.4 26.8 14.4 16.1 30.1 18.8 16.8 11.9 10.8 21.9 13.9 25.5 19.2 8.2 14.6 10.7 22.2 24.1 23.1 21.4 13.1 16.0 24.5 16.5 22.0 8.7 10.2 13.1 17.7 20.0 23.7 11.2 13.7 30.8 28.8 26.2 13.5 10.1 9.4 7.9 29.2 22.8 15.9 18.9 28.9 14.9 29.9 13.2 15.6 13.9 13.8 17.8 22.9 4.7 12.3 6.9 15.4 7.3 6.5 15.7 21.8 15.3 16.3 11.3 11.8 15.7 16.2 10.8 37.7 14.0 11.4 15.2 16.7 17.0 14.2 8.8 20.2 14.3 14.3 20.0 18.0 15.8 25.1 21.9 6.5 16.1 16.6 13.5 18.6 11.9 15.8 17.3 8.5 10.9 18.5 19.2 19.4 25.5 13.9 10.8 16.9 8.2 16.7 19.7 20.2 33.0 20.9 19.1 19.7 22.7 36.7 15.4 11.9 38.2 22.7 8.2 14.2 9.9 12.2 10.2 34.8 30.7 14.0 3.9 27.7 29.9 18.9 3.4 20.0 9.5 46.7 21.7 14.9 21.7 11.4 43.9 14.0 33.1 19.1 10.3 30.7 42.1 2.2 19.0 27.8 16.9 25.2 14.0 17.9 18.8 8.6 23.3 23.8 13.4 19.4 14.4 70.2 48.5 18.1 14.9 21.7 13.9 7.9 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038838, HPA038839" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA Vesicles "Nucleoplasm, Cytosol" "HPA038838: AB_10673120, HPA038839: " "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 16.7 13.2 13.7 18.3 16.7 28.4 18.8 21.8 18.1 18.2 16.2 14.8 10.5 11.3 21.0 12.9 10.8 15.9 14.2 19.7 10.0 15.4 14.4 10.6 16.6 14.9 11.8 10.5 16.3 16.4 26.3 25.6 16.2 18.9 15.3 12.9 12.5 11.8 16.8 23.6 11.0 14.4 18.2 12.1 14.7 13.8 13.7 14.7 23.2 18.8 9.7 14.3 17.3 19.7 4.6 5.0 5.5 4.2 6.2 7.2 1.8 5.0 7.3 8.4 6.9 13.4 10.4 8.0 12.4 13.6 10.9 14.1 9.3 3.9 5.9 7.3 12.6 13.7 8.8 12.2 10.8 13.0 12.1 5.9 23.3 14.7 4.5 9.3 16.4 11.2 11.2 6.1 13.4 10.9 10.7 12.3 12.0 13.3 9.0 13.5 2.8 8.8 4.9 4.8 13.4 7.6 11.7 11.6 5.1 11.0 11.9 8.6 7.6 16.2 8.6 5.7 10.2 8.3 8.6 16.8 13.5 8.3 12.0 12.5 10.6 18.0 17.1 9.2 10.4 12.1 4.4 3.0 5.2 5.7 4.2 6.5 4.1 5.9 6.9 2.9 4.6 5.9 7.2 5.5 6.2 3.4 5.0 4.1 1.8 13.7 16.7 21.8 18.1 10.0 15.4 11.8 10.5 18.9 14.7 44.7 27.8 14.6 10.3 9.4 26.8 24.5 17.8 17.4 25.0 8.7 25.5 10.4 0.0 8.8 11.6 17.9 10.8 0.0 12.5 6.2 15.0 9.4 27.7 8.5 7.3 30.2 13.8 14.7 16.2 13.2 15.0 10.5 8.5 10.0 10.0 15.6 8.9 9.1 19.4 6.7 39.2 12.9 19.1 25.3 14.9 6.4 30.9 20.8 10.0 7.4 UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564062-42693504 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Erythroid cells: 93.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 25.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 25.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" 19.8 18.8 14.4 21.8 16.7 22.1 18.6 26.6 20.4 17.2 19.3 17.8 17.8 20.1 29.5 16.8 16.2 15.6 16.2 16.8 13.8 13.2 17.8 24.0 19.3 18.0 16.7 12.9 20.8 24.6 28.0 26.3 16.3 17.2 16.5 20.1 15.8 18.3 15.6 33.5 18.0 24.6 19.9 15.9 21.3 18.2 9.2 17.2 26.1 20.1 14.9 17.7 18.9 29.8 3.6 3.5 25.2 5.7 3.9 4.4 1.9 14.4 7.3 8.5 13.3 17.5 16.9 11.5 11.1 12.0 9.9 10.3 10.5 6.0 9.9 8.9 12.0 11.5 14.6 12.2 9.5 12.6 13.3 8.6 15.7 10.8 13.6 14.2 15.1 10.8 11.9 10.4 9.8 10.8 12.2 11.1 14.4 18.3 12.6 9.4 11.6 11.8 13.4 7.7 28.5 7.1 10.6 12.7 14.8 11.3 12.6 10.1 8.0 11.2 10.8 10.9 13.5 10.6 14.7 16.0 9.0 7.1 11.0 8.0 11.7 10.3 15.3 4.7 11.4 5.4 10.4 4.6 9.2 4.4 4.8 3.7 3.4 2.9 3.4 3.5 3.6 3.0 3.3 25.2 3.9 5.7 2.6 3.3 1.9 14.4 16.7 26.6 20.4 13.8 13.2 16.7 12.9 17.2 17.2 14.9 21.1 12.8 17.4 14.7 41.6 32.9 22.9 25.4 22.7 19.2 56.9 14.8 14.9 14.7 4.6 21.1 31.4 93.5 13.2 11.0 18.8 19.9 19.7 28.1 12.0 60.4 12.1 18.4 28.9 3.9 23.6 24.6 18.6 17.2 19.6 23.5 14.1 22.9 22.6 9.6 50.0 38.8 23.4 9.2 8.1 14.2 14.4 32.0 18.0 18.7 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3 (putative)" Q6ZT12 2 169827458-170084131 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.3" "Cell type enhanced" "Detected in all" 4 "Cardiomyocytes: 97.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 11.9 15.5 10.9 6.1 18.3 5.4 9.6 15.5 18.9 9.9 10.0 9.8 9.1 6.7 11.5 7.1 10.7 8.1 7.8 23.1 10.3 7.2 12.9 16.9 9.2 5.6 11.9 14.0 8.9 9.8 20.9 14.9 7.2 14.7 11.2 7.3 8.0 11.1 9.2 76.3 11.5 8.4 9.6 10.2 6.9 9.2 7.9 11.4 6.3 14.9 10.9 6.0 12.8 8.7 2.0 2.8 1.9 2.1 2.4 4.3 1.2 8.9 7.6 8.1 10.7 16.2 12.9 6.8 16.2 9.4 9.4 7.6 11.7 5.7 10.2 14.1 12.6 7.6 11.9 9.7 8.2 11.7 10.5 8.3 37.1 8.1 12.3 8.1 12.2 12.0 7.7 7.7 12.3 8.2 7.5 9.2 5.1 19.3 11.1 16.0 8.4 7.9 6.0 6.3 9.1 6.4 7.6 13.3 10.8 6.8 12.7 16.0 8.7 11.4 10.5 6.5 6.8 6.9 6.9 11.7 14.2 5.7 11.1 10.2 9.0 7.0 9.4 11.7 7.2 7.8 0.0 2.1 1.7 3.2 1.8 4.2 2.0 1.9 2.7 2.8 1.2 3.3 4.3 1.9 2.4 1.6 2.4 3.1 1.2 10.9 18.3 15.5 18.6 10.3 7.2 11.9 14.0 14.7 11.4 41.7 21.1 7.5 11.4 23.0 40.4 97.6 15.3 9.4 19.4 12.2 76.6 14.8 3.3 8.0 6.6 23.7 13.4 23.3 9.5 6.8 18.3 22.3 16.1 32.7 8.9 60.4 16.0 31.9 21.5 7.4 23.9 16.8 15.1 4.6 12.5 63.3 9.4 14.0 18.0 10.2 53.7 25.8 26.4 13.0 7.6 25.3 19.2 13.1 9.9 12.3 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074506-19210276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Basal keratinocytes: 240.8;Suprabasal keratinocytes: 220.9;Urothelial cells: 215.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 24.4 25.4 22.4 29.0 25.4 58.3 23.7 28.5 32.5 22.4 28.5 26.3 31.5 18.2 34.0 32.5 22.7 20.3 27.3 20.5 23.3 15.9 25.5 29.7 31.2 20.3 21.0 20.9 35.5 21.0 40.9 31.4 28.4 25.0 30.7 20.5 30.6 24.7 27.1 55.9 69.0 25.5 39.3 20.2 26.5 30.2 41.1 21.6 37.7 26.1 17.3 25.9 43.4 29.0 4.6 9.1 18.3 18.5 2.7 3.4 4.6 22.2 22.5 20.4 15.0 38.1 19.7 17.6 17.3 18.4 18.9 17.3 35.9 19.2 13.4 16.3 22.9 16.6 15.3 15.9 17.3 17.7 11.1 14.1 30.7 21.7 23.3 26.9 18.8 20.4 17.6 22.2 38.5 37.2 18.5 20.7 23.9 21.0 12.5 17.9 15.9 8.9 22.9 16.5 45.7 12.7 12.4 15.9 11.2 17.1 13.1 14.4 14.3 20.5 11.8 14.8 19.5 8.2 14.8 32.0 22.2 13.9 26.2 19.4 14.9 9.0 15.6 15.2 29.1 18.8 18.3 18.5 2.9 3.4 3.8 2.9 4.6 3.0 1.9 9.1 2.9 2.7 2.5 9.8 2.7 1.3 4.3 2.1 4.6 22.4 25.4 28.5 32.5 23.3 15.9 21.0 20.9 25.0 21.6 32.8 42.3 16.3 79.1 240.8 54.0 15.6 40.8 30.8 26.1 29.6 143.3 19.2 11.6 31.4 14.7 21.1 36.4 23.3 35.5 14.1 29.1 39.1 18.5 77.9 54.8 74.7 16.8 28.8 47.4 19.9 28.4 42.8 47.2 36.1 30.4 30.7 51.2 14.0 33.6 88.2 48.0 19.4 26.8 37.4 17.9 220.9 28.4 21.0 19.5 215.5 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102253012-102412841 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA053688: AB_2682230" "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 27.0 16.7 27.1 29.5 31.7 30.3 29.2 40.8 32.8 24.9 25.0 19.1 21.1 14.4 26.8 24.0 23.8 22.0 17.6 22.7 25.5 15.3 17.9 17.0 24.2 29.6 21.9 20.6 29.7 22.2 32.4 25.5 25.0 23.6 20.2 17.1 19.7 22.9 21.8 39.9 29.7 22.4 29.3 17.5 21.9 21.1 39.7 28.3 37.9 20.3 15.9 27.0 27.5 28.6 5.0 4.0 6.3 5.5 2.4 7.1 2.1 23.6 10.6 20.5 10.4 20.2 20.6 18.9 17.9 15.8 14.0 12.3 10.6 15.9 47.1 15.5 16.7 9.2 14.4 17.5 15.5 19.7 20.4 8.6 39.3 14.5 19.0 18.0 12.2 21.7 23.6 15.5 14.4 25.2 16.0 16.8 13.5 18.9 26.8 13.7 21.4 31.0 14.6 15.4 22.9 12.0 18.1 12.1 22.3 12.8 23.2 15.1 12.6 12.5 12.1 12.4 18.6 19.6 13.0 16.8 15.0 17.5 13.4 12.4 14.4 13.8 48.5 14.8 19.1 12.1 3.1 3.4 5.0 5.6 3.4 5.6 5.0 6.0 5.9 4.0 3.9 4.8 7.1 6.3 2.4 5.5 3.6 7.1 2.1 27.1 31.7 40.8 32.8 25.5 15.3 21.9 20.6 23.6 28.3 23.8 27.7 29.8 38.5 46.4 48.4 35.8 5.1 40.2 63.7 29.6 64.8 19.1 8.3 15.1 25.0 38.3 17.3 0.0 13.1 14.9 48.2 37.7 28.9 15.8 15.4 54.0 32.0 23.4 29.4 20.2 36.8 28.9 42.2 27.1 17.9 31.5 16.2 17.3 34.3 6.7 44.0 12.9 38.7 64.7 30.4 53.3 58.2 30.5 17.7 46.9 UBR7 C14orf130 ENSG00000012963 "Ubiquitin protein ligase E3 component n-recognin 7 (putative)" Q8N806 14 93207056-93229215 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 246.4;Late spermatids: 271.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000861 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA000861: AB_1078321" "unprognostic (9.60e-2)" "unprognostic (5.12e-3)" "unprognostic (1.11e-1)" "unprognostic (9.20e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (8.12e-5)" "unprognostic (1.14e-1)" "unprognostic (9.83e-2)" "unprognostic (1.04e-2)" "unprognostic (4.30e-2)" "unprognostic (5.94e-2)" "prognostic favorable (9.76e-5)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" 14.1 12.3 16.4 12.5 22.9 17.0 17.5 20.0 25.8 17.1 15.7 17.7 11.3 11.1 14.9 13.4 14.8 13.7 11.9 19.0 14.2 12.8 15.3 13.2 11.9 18.0 14.0 17.1 17.0 20.4 28.2 11.5 11.4 13.3 13.9 17.1 13.6 13.7 14.9 19.9 15.2 12.7 14.1 16.9 13.8 14.1 21.1 14.3 31.9 15.4 12.9 23.3 13.4 13.3 18.1 10.7 15.8 9.5 11.5 16.5 8.2 6.5 8.7 13.5 11.2 6.3 6.8 4.8 13.8 9.8 15.4 11.7 6.3 7.4 15.5 11.6 7.0 6.7 7.9 14.4 7.7 15.8 12.0 7.8 11.2 9.4 6.0 2.9 16.4 12.6 4.1 5.4 8.5 5.4 5.7 8.6 14.9 10.4 15.6 14.7 19.1 26.6 9.0 6.2 17.2 15.9 20.5 24.1 8.5 5.2 10.7 16.9 12.1 9.9 8.3 4.1 8.3 15.0 11.3 6.5 11.3 6.1 9.7 14.2 18.1 27.7 16.0 9.9 12.7 9.6 15.8 7.3 11.8 12.7 9.1 13.3 18.1 11.4 11.7 7.8 14.8 10.0 10.6 11.5 11.5 9.5 10.7 16.5 8.2 16.4 22.9 20.0 25.8 14.2 12.8 14.0 17.1 13.3 14.3 14.9 5.4 14.3 6.6 17.6 5.8 15.3 10.2 2.7 10.3 10.4 9.8 7.8 10.0 8.8 246.4 8.2 9.2 23.3 11.2 13.2 10.2 4.3 4.7 10.4 11.8 3.2 5.2 14.1 10.1 271.2 8.6 8.5 13.5 7.2 7.6 12.6 8.2 5.8 11.7 7.0 13.4 6.5 10.7 34.9 27.7 11.8 5.5 10.7 10.7 3.3 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760248-233773299 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 48.6;liver: 120.3" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 83.9" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "neutrophil: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 8.1;OE19: 35.4;RT4: 19.3" "Not detected" "Not detected" NA NA "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.2 35.6 0.1 0.1 48.6 0.1 0.1 4.3 0.0 0.3 0.1 0.1 0.0 4.5 120.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.4 0.1 0.7 0.1 0.1 0.9 48.2 0.5 0.1 0.1 1.3 0.2 0.1 0.1 0.2 0.1 0.1 5.2 0.8 1.0 0.4 4.7 0.4 1.1 0.5 0.2 0.2 0.6 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 3.1 0.2 0.1 1.4 0.0 0.0 8.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.8 0.0 0.3 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.4 0.0 0.2 0.3 35.4 3.6 0.0 0.1 0.3 0.0 19.3 0.1 0.2 1.4 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.4 0.2 0.1 2.1 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.3 0.1 1.0 0.4 0.5 4.7 1.1 0.4 0.4 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.7 6.8 1.8 0.0 0.0 0.0 0.2 2.8 0.0 3.5 0.0 0.0 0.0 0.0 0.9 0.0 83.9 0.0 0.0 0.0 1.3 3.3 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.5 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 6.2 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 9.4;gallbladder: 8.4;intestine: 31.1;stomach 1: 12.4" "Cell type enhanced" "Detected in some" 22 "Club cells: 1.2;Enterocytes: 2.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 142 "RT4: 109.0" "Intracellular and membrane" NA NA "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.3 0.0 0.3 2.6 0.3 0.0 0.3 0.3 0.3 0.3 19.2 0.3 0.3 31.1 0.3 0.3 9.4 0.1 8.4 0.3 0.3 0.0 0.3 1.4 0.6 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 14.3 0.3 0.9 0.3 0.3 0.3 20.2 0.5 0.3 0.3 12.4 1.0 0.3 0.3 0.3 0.3 1.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 109.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.3 0.3 0.0 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 UGT1A3 UGT1C ENSG00000243135 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729108-233773299 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 40.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 16.7" NA NA "unprognostic (5.15e-2)" "unprognostic (9.93e-2)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" "unprognostic (1.04e-4)" "unprognostic (8.22e-2)" "unprognostic (2.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718778-233773299 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "liver: 99.4" "Group enriched" "Detected in some" 8 "Club cells: 4.5;Hepatocytes: 10.5" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.6;HL-60: 1.4;RH-30: 2.2" NA NA "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A5 UGT1E ENSG00000240224 "UDP glucuronosyltransferase family 1 member A5" P35504 2 233712992-233773299 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 3.7;intestine: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;RT4: 1.6" NA NA "unprognostic (2.18e-3)" "unprognostic (1.36e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 11.2 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 9.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 111.7;liver: 50.1;urinary bladder: 32.7" "Group enriched" "Detected in some" 5 "Early spermatids: 37.7;Late spermatids: 19.3" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 40.4;OE19: 160.5" "CAB009819, HPA054065" Enhanced NA NA "CAB009819: AB_2241481, HPA054065: AB_2682367" "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.8 0.5 0.2 0.5 2.0 0.3 0.9 13.0 0.0 1.1 0.1 0.1 0.0 111.7 50.1 1.9 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.3 0.1 3.3 0.4 0.1 1.3 1.2 0.1 3.8 1.2 2.3 0.1 0.1 8.1 0.2 0.1 0.5 0.2 5.6 8.7 32.7 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.2 0.0 11.3 0.0 0.1 40.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 160.5 0.0 0.0 0.0 0.0 0.4 20.4 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.8 0.0 0.3 0.0 0.0 4.5 1.8 0.0 0.0 0.0 0.0 37.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.0 0.6 0.0 19.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.0 1.0 0.0 0.0 0.0 2.1 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "esophagus: 54.4;lymphoid tissue: 40.2;tongue: 23.6" "Cell type enriched" "Detected in some" 5 "Urothelial cells: 8.4" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 14 "SiHa: 50.6" NA NA "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.1 0.0 0.0 0.1 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 40.2 0.2 2.8 0.2 0.1 1.6 0.2 0.6 0.1 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 50.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.6 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 8.4 UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617645-233773310 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 13.0;urinary bladder: 15.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 58 "RT4: 52.5" NA NA "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (9.71e-12)" "unprognostic (9.26e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 7.3 0.0 0.0 0.0 0.0 0.0 3.3 5.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 52.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671853-233773300 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 169.8" "Cell type enhanced" "Detected in some" 29 "Club cells: 1.2;Hepatocytes: 5.9;Proximal tubular cells: 3.3" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "A549: 4.9;RT4: 4.0" NA NA "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.8 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" Q9Y4X1 4 69588417-69653249 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 10.6;liver: 14.5;pituitary gland: 21.2" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 32.3" "Cancer enhanced" "Detected in some" "liver cancer: 0.7" "Region enriched" "Detected in single" 17 "pons and medulla: 1.7" "Cell type enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 3.2;HUVEC TERT2: 1.9;U-266/70: 3.6" "HPA017261, HPA045108" Uncertain NA NA "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 14.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.7 0.0 0.0 1.5 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 2.0 0.5 0.9 0.4 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.2 1.7 0.5 0.4 0.2 0.2 0.1 0.1 0.4 0.2 0.1 0.3 0.2 0.1 2.0 0.9 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.5 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951791 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 150.5;kidney: 43.2" "Cell type enhanced" "Detected in some" 11 "Cholangiocytes: 94.3;Enterocytes: 115.5;Hepatocytes: 49.3;Paneth cells: 52.6;Proximal tubular cells: 125.8;Undifferentiated cells: 72.7" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10 "eosinophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" "Cell line enriched" "Detected in some" 9 "Hep G2: 21.0" HPA045108 Supported NA NA "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" 0.1 0.1 0.1 4.3 0.1 0.0 0.7 0.1 0.1 0.1 63.8 0.1 0.1 31.9 0.1 1.7 0.1 0.1 14.6 0.3 0.1 0.1 43.2 9.6 0.1 0.1 0.1 0.1 0.1 12.0 0.0 0.1 0.1 0.1 0.1 8.6 0.1 0.1 0.1 0.1 0.1 150.5 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 94.3 0.0 0.0 3.5 0.0 0.0 10.0 21.3 0.0 0.0 115.5 0.0 2.3 0.0 0.0 0.0 0.0 49.3 0.0 0.0 11.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 28.2 0.0 6.0 52.6 0.0 125.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.7 0.0 UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815993-68831196 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 277 "liver: 120.4" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 221.7" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 39 "Hep G2: 16.1" HPA045108 Uncertain NA NA "HPA045108: AB_2679218" "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 120.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.7 0.0 0.0 0.0 1.3 4.7 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214731 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "breast: 77.4" "Cell type enriched" "Detected in some" 7 "Cholangiocytes: 12.7" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "basophil: 6.8;eosinophil: 5.6" "Lineage enriched" "Detected in single" 68 "granulocytes: 6.8" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;HL-60: 3.1;NB-4: 2.5;RPTEC TERT1: 3.7;U-2197: 1.5" HPA045108 Uncertain NA NA "HPA045108: AB_2679218" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" 0.1 0.0 0.1 0.1 0.1 0.0 77.4 0.1 0.1 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.0 3.3 0.1 0.1 0.0 1.2 7.3 0.1 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 7.0 0.1 0.1 1.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.9 0.1 0.1 0.1 0.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.1 0.0 3.7 0.2 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.6 0.0 0.0 6.8 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646630-68670628 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 22.4;intestine: 50.7;liver: 65.4" "Group enriched" "Detected in some" 6 "Cholangiocytes: 168.2;Hepatocytes: 134.4" "Cancer enriched" "Detected in many" 10 "liver cancer: 120.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "naive B-cell: 2.7" "Lineage enhanced" "Detected in single" "B-cells: 2.7" "Cell line enhanced" "Detected in some" "A549: 3.2;HL-60: 2.2;RH-30: 1.2;RPMI-8226: 1.1" HPA045108 Approved NA NA "HPA045108: AB_2679218" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.94e-1)" "prognostic favorable (9.82e-4)" "unprognostic (6.73e-2)" "unprognostic (3.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.81e-3)" "unprognostic (2.39e-2)" "unprognostic (5.38e-2)" "prognostic favorable (4.50e-4)" 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.1 48.0 0.1 0.1 5.4 0.1 0.1 0.2 0.0 22.4 0.1 0.1 0.0 0.1 65.4 0.1 0.1 0.1 0.1 0.1 5.3 0.0 0.1 0.1 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.0 50.7 0.1 0.1 0.1 5.7 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 2.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 1.2 1.1 0.0 0.2 0.1 0.6 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.4 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 168.2 0.0 0.0 0.0 0.0 0.0 0.0 14.9 1.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 134.4 0.0 0.0 0.0 1.8 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.5 UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537184-68568527 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 68.1;liver: 21.6" "Cell type enhanced" "Detected in some" 11 "Alveolar cells type 2: 2.2;Cholangiocytes: 2.5;Ciliated cells: 1.4;Club cells: 1.2;Hepatocytes: 1.3;Intestinal endocrine cells: 1.7;Melanocytes: 3.3" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "memory B-cell: 3.3;naive B-cell: 11.9" "Lineage enriched" "Detected in single" 59 "B-cells: 11.9" "Group enriched" "Detected in some" 7 "BEWO: 3.1;NB-4: 3.6;RPMI-8226: 5.2;SH-SY5Y: 2.3;U-2197: 2.1" HPA045108 Supported NA NA "HPA045108: AB_2679218" "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" 0.4 0.1 0.4 4.7 0.4 0.0 0.4 0.4 0.4 0.4 55.6 0.4 0.4 54.1 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.1 0.4 21.6 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 20.7 0.4 0.4 0.4 0.4 0.1 68.1 1.1 0.4 0.4 0.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 11.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.2 0.0 0.0 0.0 5.2 0.2 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.4 0.0 2.2 0.0 0.0 0.0 0.0 0.0 2.5 1.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 1.7 0.6 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280499-69295050 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 71.7;salivary gland: 25.6" "Cell type enriched" "Detected in single" 178 "Cholangiocytes: 17.8" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "basophil: 2.5;eosinophil: 4.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 4.0" "Group enriched" "Detected in some" 10 "Daudi: 7.1;NB-4: 6.5" HPA045108 Uncertain "Intracellular and membrane" NA NA "HPA045108: AB_2679218" "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 71.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 25.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.2 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 105 "liver: 175.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 831.9" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "RH-30: 10.4" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.1 175.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 34.2 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.0 0.0 0.0 0.0 0.0 0.0 831.9 0.1 0.0 0.0 14.7 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 125.4;liver: 156.0" "Group enriched" "Detected in many" 6 "Hepatocytes: 539.4;Proximal tubular cells: 775.7" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 21.0;RPTEC TERT1: 83.6" HPA045108 Uncertain NA NA "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" 0.1 0.1 0.1 0.2 0.1 0.0 0.4 0.1 0.1 3.1 7.9 0.1 2.5 6.4 0.6 4.7 0.1 4.7 1.5 0.1 0.1 0.1 125.4 156.0 0.2 0.1 0.1 0.1 0.6 14.7 0.0 0.1 0.2 0.1 0.3 0.4 0.2 1.0 2.7 0.3 0.2 27.7 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 83.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 3.9 0.6 0.1 0.0 0.0 58.6 0.0 0.0 118.7 0.0 0.0 82.9 5.6 0.2 0.0 6.7 0.0 9.1 0.0 0.0 0.4 0.0 539.4 0.1 0.0 3.4 6.2 10.7 0.0 1.7 0.0 3.3 0.0 20.1 0.0 11.8 11.9 0.0 775.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 2.0 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951010-36001028 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 44.0;liver: 47.7" "Group enriched" "Detected in some" 5 "Collecting duct cells: 47.1;Early spermatids: 91.4;Hepatocytes: 63.1;Proximal tubular cells: 58.6" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 42 "RH-30: 25.3" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Vesicles, Cytosol" "HPA047697: AB_2680122, HPA056290: AB_2683088" "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 5.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 44.0 47.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.0 3.2 0.1 6.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.4 0.2 0.2 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.4 0.0 0.0 0.0 47.1 0.0 0.0 3.3 0.0 91.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.1 0.1 0.0 0.0 2.5 2.2 12.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 58.6 0.3 6.5 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.0 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035017-36071358 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 37.0;skin 1: 14.4;testis: 13.2" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.5;Early spermatids: 3.6;Late spermatids: 5.7;Proximal tubular cells: 3.3" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Region enhanced" "Detected in single" "pons and medulla: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.2;MOLT-4: 9.3;REH: 21.8;SuSa: 9.8;T-47d: 5.7;THP-1: 12.8" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.1 1.1 0.1 0.0 0.2 6.4 1.6 0.1 0.6 0.1 0.1 0.5 0.4 0.0 0.1 0.8 0.1 0.1 0.2 0.2 0.1 0.6 5.6 0.8 0.1 0.0 0.5 0.0 0.2 0.0 0.0 1.7 0.2 2.0 0.6 0.0 2.9 0.1 0.0 0.1 14.4 0.1 0.0 0.3 1.4 0.1 13.2 0.0 37.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 1.0 0.0 0.4 5.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 9.3 0.0 3.9 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 5.7 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.6 0.1 0.6 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529629 "Enzymes, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071190 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes No "Nucleoplasm, Golgi apparatus" Midbody "HPA071190: AB_2686358" "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 21.6 22.0 23.5 18.9 26.2 30.1 23.5 10.8 30.5 14.3 16.3 17.2 30.8 16.3 11.5 12.9 16.0 12.9 12.1 11.4 27.0 31.8 27.9 32.4 16.9 24.3 30.6 20.3 12.1 11.8 25.0 12.5 16.5 33.4 14.7 17.4 14.1 15.9 22.9 30.6 11.5 21.8 9.6 20.5 21.3 16.8 10.4 14.1 23.0 17.1 11.7 24.1 16.1 12.8 5.7 4.3 4.5 9.2 5.9 8.5 4.0 21.1 9.9 5.2 12.7 14.9 11.8 11.7 28.0 15.3 23.0 16.6 6.4 13.3 17.3 24.5 20.9 11.2 12.3 9.9 15.5 37.1 23.7 7.2 17.1 12.3 5.8 11.5 24.9 20.0 12.1 16.4 22.6 21.7 16.1 13.2 12.0 14.9 24.1 39.4 8.9 13.2 6.6 6.9 15.9 13.4 8.5 23.3 14.4 15.3 21.9 9.5 8.8 24.7 23.0 18.0 7.5 19.9 28.0 20.5 26.3 14.9 18.1 39.0 25.0 34.7 20.5 21.9 12.2 23.8 4.5 3.3 3.7 8.2 8.6 8.5 5.4 6.2 6.8 3.6 5.7 6.3 7.1 2.0 5.9 9.2 4.3 4.9 4.0 23.5 26.2 10.8 30.5 27.0 31.8 30.6 20.3 33.4 14.1 17.9 32.1 50.1 25.7 26.2 21.7 29.4 56.0 41.5 50.0 50.6 11.8 22.6 48.0 23.2 35.7 30.8 40.7 0.0 20.2 32.6 19.3 44.8 45.0 71.0 27.6 22.3 32.1 35.0 64.6 34.6 19.8 51.7 27.0 44.1 35.0 13.6 28.8 34.8 18.4 49.4 21.6 0.0 27.3 23.4 22.0 21.5 18.8 52.2 31.1 52.1 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 75.6" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 5.8;Hofbauer cells: 7.5;Spermatogonia: 6.9" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 8.2" "Group enriched" "Detected in many" 4 "dendritic cells: 8.2;T-cells: 4.2" "Cell line enhanced" "Detected in many" "MOLT-4: 63.9;REH: 145.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 8.2 3.7 16.5 0.7 0.3 4.2 0.3 1.5 1.6 0.0 2.1 0.3 0.2 2.0 0.0 1.0 0.9 1.2 0.1 0.1 0.3 10.0 4.3 0.7 0.3 0.6 0.0 0.0 1.0 1.4 0.0 1.4 0.0 0.0 0.0 0.3 1.9 2.2 0.8 0.7 2.2 1.9 3.1 4.0 75.6 0.0 4.0 6.6 1.1 0.0 0.4 8.2 1.5 0.4 0.9 4.2 0.9 15.9 11.6 17.5 12.4 0.5 2.0 2.8 13.0 6.2 13.6 13.2 13.8 8.1 9.1 3.2 5.7 4.9 8.0 12.0 7.0 9.6 14.7 13.7 7.8 10.8 14.7 0.2 19.3 11.9 1.0 0.5 7.3 1.9 2.1 4.0 14.4 11.2 10.5 8.1 12.5 63.9 11.8 7.8 5.8 12.5 145.0 39.1 6.6 3.7 11.7 13.0 10.3 10.2 5.6 1.8 2.9 10.1 18.4 5.0 14.4 11.7 18.6 15.7 4.5 4.6 26.8 8.3 18.8 18.3 0.6 0.4 0.2 1.1 0.1 0.1 0.3 1.5 1.9 2.2 0.4 0.4 1.5 1.5 0.9 0.3 8.2 4.2 0.9 0.0 0.0 1.5 0.6 0.0 2.6 1.6 2.5 1.4 1.2 0.0 0.0 1.7 0.0 1.7 2.5 0.0 0.9 0.0 0.3 5.8 0.5 0.5 0.0 0.6 7.5 3.2 0.0 0.0 2.1 0.9 0.6 0.7 0.0 2.8 1.5 0.5 2.6 1.9 0.4 0.0 0.8 0.0 1.5 4.2 6.9 0.0 1.1 0.0 4.7 0.7 UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm NA NA Nucleoplasm "HPA026633: AB_2732431, HPA026697: AB_2732432" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" 14.1 12.9 10.6 25.4 12.2 49.1 19.0 24.8 11.8 18.6 15.6 12.7 17.6 7.9 17.5 15.1 13.3 12.0 11.9 11.3 10.2 10.6 10.1 9.8 13.5 19.3 12.3 10.5 18.9 14.5 12.7 12.7 14.6 11.4 19.3 12.0 10.7 13.0 16.4 15.7 11.0 12.0 17.1 12.2 14.1 11.6 10.6 14.8 40.3 15.2 10.2 19.8 18.7 18.2 5.1 2.5 7.5 1.4 1.2 3.6 1.2 6.7 7.7 11.1 4.7 9.1 13.2 8.1 15.6 9.6 9.8 17.2 4.9 4.9 10.3 3.4 7.7 9.1 4.4 10.2 9.1 15.0 18.7 4.7 18.0 15.0 7.8 7.5 8.4 6.1 5.9 5.9 7.6 18.8 18.8 38.2 10.6 1.7 10.1 23.1 2.3 14.1 32.7 4.3 9.9 5.7 16.0 5.1 3.6 7.3 4.6 10.0 3.9 6.7 4.5 9.7 14.1 5.6 16.9 32.2 10.5 3.8 4.3 13.0 2.7 8.0 12.1 5.1 7.4 4.1 7.5 1.1 4.3 2.3 0.9 1.7 3.5 3.6 1.8 0.7 5.1 2.3 3.0 1.3 1.2 1.4 2.5 3.5 1.2 10.6 12.2 24.8 11.8 10.2 10.6 12.3 10.5 11.4 14.8 6.0 11.8 25.0 9.7 19.2 22.6 42.0 5.1 5.3 9.1 12.2 29.5 10.8 1.7 5.1 16.0 20.4 8.1 23.3 3.4 8.5 12.4 13.9 17.3 11.3 9.2 27.0 6.8 15.4 11.7 5.9 17.8 11.0 20.3 6.4 12.4 6.7 6.0 12.9 13.8 5.1 34.9 12.9 13.7 37.2 17.2 16.7 4.9 13.8 11.3 7.1 ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894651-131923167 "Enzymes, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Horizontal cells: 50.9;Rod photoreceptor cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9;plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol NA NA Cytosol "HPA063990: AB_2685167" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (2.52e-3)" "unprognostic (2.21e-3)" "unprognostic (8.01e-3)" "unprognostic (5.48e-2)" "unprognostic (2.74e-2)" "unprognostic (5.04e-3)" "unprognostic (3.94e-3)" "unprognostic (2.03e-2)" "unprognostic (9.09e-3)" "unprognostic (8.19e-2)" "unprognostic (6.25e-2)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.82e-2)" "unprognostic (3.16e-1)" 10.9 18.6 14.6 9.2 49.6 33.2 8.9 24.0 24.4 14.4 11.8 6.9 13.3 11.7 16.5 10.7 9.8 10.6 16.2 17.4 11.5 8.3 9.0 15.8 9.0 8.3 7.9 12.0 18.2 59.6 13.8 23.8 17.2 11.6 13.4 4.0 13.9 18.1 13.4 33.4 24.3 11.5 10.2 5.4 16.5 11.4 11.4 11.4 13.8 10.7 9.6 6.5 12.1 10.9 0.6 6.4 6.9 1.7 0.2 0.8 0.6 5.2 16.9 7.8 9.7 3.5 2.9 10.7 8.3 6.0 3.6 2.9 3.6 5.4 1.4 8.8 5.8 7.2 5.2 1.7 3.3 1.0 5.6 10.2 3.5 13.8 4.9 6.6 2.5 7.8 5.3 9.1 3.9 1.6 9.9 4.4 10.8 4.6 4.2 2.3 11.9 15.6 14.7 8.6 2.4 16.2 11.8 2.8 6.9 2.1 6.5 19.9 11.0 8.9 9.2 4.6 8.3 13.9 17.1 8.3 8.5 5.1 14.8 3.8 18.6 6.7 1.9 14.4 4.4 9.8 0.2 1.7 2.3 0.8 0.7 0.2 0.1 0.7 0.7 0.3 0.6 0.5 0.5 6.9 0.2 0.7 6.4 0.5 0.6 14.6 49.6 24.0 24.4 11.5 8.3 7.9 12.0 11.6 11.4 14.9 16.7 11.8 5.7 12.8 23.0 18.0 17.8 4.0 11.4 7.0 37.3 4.0 1.7 8.0 0.7 12.0 5.2 0.0 10.9 2.6 9.3 12.0 3.5 23.1 4.8 50.9 18.4 6.2 11.9 1.9 11.5 5.4 5.0 3.6 15.4 12.6 18.3 7.0 14.9 2.4 87.3 12.9 10.3 3.9 5.9 16.9 14.4 8.3 8.3 6.9 ULK2 "ATG1B, KIAA0623, Unc51.2" ENSG00000083290 "Unc-51 like autophagy activating kinase 2" Q8IYT8 17 19770829-19867936 "Enzymes, Predicted intracellular proteins" "Autophagy, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 51.2;Spermatocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9;non-classical monocyte: 5.8" "Lineage enriched" "Detected in many" 4 "monocytes: 6.9" "Cell line enhanced" "Detected in many" "SuSa: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037021 Approved NA NA "CAB037021: AB_1841237" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.11e-3)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-1)" "unprognostic (1.38e-2)" 10.3 7.1 15.5 4.4 19.1 2.8 7.6 15.5 21.8 9.3 7.2 28.3 6.7 3.1 9.5 8.4 6.8 11.5 7.7 8.3 15.0 10.9 7.0 3.7 8.8 4.6 15.8 12.0 12.4 7.5 14.2 4.2 8.5 15.9 9.0 4.8 8.5 5.3 11.0 13.5 7.8 3.6 9.9 28.3 7.1 5.5 33.0 14.6 2.0 7.0 1.4 3.8 7.7 6.3 0.1 1.4 0.5 6.9 0.4 1.6 0.6 7.5 7.8 11.2 1.5 6.6 12.4 0.0 6.3 7.8 6.6 6.2 0.1 1.6 0.0 3.3 8.1 7.5 3.6 0.0 1.3 6.3 6.2 8.1 0.2 3.3 0.0 8.6 0.0 3.8 8.0 9.8 3.3 2.8 5.8 4.6 0.0 0.0 0.0 5.5 2.1 0.0 0.3 1.6 0.1 2.0 0.4 0.0 0.0 4.8 3.3 2.8 11.7 9.9 1.3 3.5 29.0 7.7 2.9 7.3 0.0 1.0 2.4 3.8 0.0 0.0 0.0 1.0 0.0 2.3 0.0 1.5 0.3 0.6 6.9 0.2 0.1 1.0 1.0 1.4 0.1 1.6 1.0 0.5 0.4 5.8 0.1 0.2 0.6 15.5 19.1 15.5 21.8 15.0 10.9 15.8 12.0 15.9 14.6 17.9 10.2 0.0 4.2 6.5 15.9 9.5 7.6 8.1 7.9 7.0 7.9 6.4 3.3 3.0 27.9 2.9 0.7 0.0 2.9 2.6 9.0 6.0 0.0 1.7 7.1 14.3 2.4 3.7 16.1 51.2 13.0 5.1 8.5 4.6 3.2 5.6 2.3 3.2 11.7 4.5 10.6 12.9 11.3 38.8 20.5 8.4 2.4 3.8 2.1 3.4 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836116-74843346 "Enzymes, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 75.1;Horizontal cells: 84.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved NA NA "HPA040474: AB_2677003" "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favorable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.0 11.7 11.8 8.4 15.4 2.9 7.4 21.3 20.4 7.9 13.8 9.0 9.0 7.9 5.3 9.5 33.9 6.7 9.6 14.1 11.8 8.9 13.4 9.3 6.4 7.9 11.2 15.3 4.9 14.7 12.1 12.3 5.7 21.1 8.2 14.4 10.4 10.4 7.4 19.1 24.6 20.3 7.2 5.8 9.9 11.1 6.0 7.6 4.2 6.1 10.9 13.7 8.6 10.6 3.8 4.2 3.8 7.8 5.8 12.6 4.9 3.9 10.7 5.6 9.7 6.4 4.2 3.7 3.1 4.5 6.5 7.1 4.2 8.9 8.5 6.0 3.5 7.5 4.0 15.6 4.3 2.7 16.2 15.4 25.2 13.6 5.1 9.3 6.0 16.2 5.5 8.6 5.7 5.4 2.4 9.8 11.8 6.9 9.2 5.3 5.8 4.4 6.2 6.2 9.3 5.5 13.0 6.8 16.1 4.2 5.0 10.4 13.2 6.1 5.8 19.3 5.9 8.4 15.1 5.5 8.7 5.6 8.6 6.7 12.8 11.6 6.2 4.9 17.7 7.5 3.8 3.6 1.4 12.6 7.8 10.1 3.8 7.4 10.3 4.0 3.5 8.1 5.5 0.9 5.8 6.2 4.2 9.7 4.9 11.8 15.4 21.3 20.4 11.8 8.9 11.2 15.3 21.1 7.6 8.9 11.7 3.7 6.8 9.0 75.1 15.1 7.6 2.7 2.3 12.2 15.7 7.1 16.6 9.2 0.8 8.4 42.8 0.0 10.2 2.5 7.3 8.4 20.7 11.0 13.7 84.2 10.9 13.5 6.3 1.5 12.0 6.5 5.0 19.0 17.8 18.4 10.1 16.4 11.0 13.3 54.3 0.0 7.6 9.4 19.8 19.1 4.8 17.0 20.4 7.2 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 279.5;Late spermatids: 329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 4.3 4.8 5.1 4.7 8.3 10.3 4.2 4.3 5.4 11.9 2.8 5.9 6.0 2.1 10.7 10.9 2.8 12.3 3.1 13.1 5.2 3.0 5.4 3.4 5.5 4.2 3.1 4.2 4.5 3.6 13.5 19.7 9.0 5.8 4.4 2.8 6.7 4.2 4.5 1.4 3.5 3.3 5.1 5.7 4.4 3.4 27.5 3.4 6.3 7.1 1.7 8.4 4.0 6.0 6.4 5.1 10.7 6.3 2.6 10.3 5.2 7.3 1.7 2.7 3.0 1.1 1.7 4.6 2.5 2.6 3.1 2.6 0.9 2.2 8.6 1.4 5.8 3.0 3.7 3.2 1.9 2.8 1.1 0.9 1.6 5.4 2.9 3.9 5.6 1.7 1.6 2.2 15.0 3.1 3.9 2.1 5.9 1.9 7.2 2.2 5.9 7.0 4.5 3.3 1.8 3.1 1.6 8.5 3.7 6.5 7.1 1.4 9.9 2.6 1.2 2.1 1.8 3.0 1.8 6.2 2.0 2.2 13.2 2.1 4.3 8.0 3.6 11.0 5.9 2.4 5.7 5.8 5.8 8.0 6.3 6.5 5.6 8.6 7.2 5.1 6.4 6.5 9.2 10.7 2.6 3.2 4.6 10.3 5.2 5.1 8.3 4.3 5.4 5.2 3.0 3.1 4.2 5.8 3.4 8.9 5.8 1.9 2.8 1.8 5.4 12.8 5.1 53.5 4.5 3.5 51.1 2.8 0.0 2.3 279.5 4.4 1.1 0.0 2.1 3.9 3.3 1.2 1.1 5.9 6.5 11.1 1.7 1.8 4.1 329.6 6.1 5.6 0.0 6.4 1.1 11.2 2.8 0.0 3.9 5.0 25.1 6.5 3.3 29.9 8.7 3.1 3.5 4.4 1.7 0.8 USP1 ENSG00000162607 "Ubiquitin specific peptidase 1" O94782 1 62436297-62451804 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.6" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 281.4;Spermatogonia: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028387, HPA028440" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA028387: AB_2672578, HPA028440: AB_10603000" "unprognostic (1.22e-1)" "unprognostic (5.36e-2)" "unprognostic (1.78e-3)" "unprognostic (4.05e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (6.72e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (3.33e-3)" "unprognostic (3.99e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-3)" "unprognostic (5.70e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" 11.6 9.0 11.3 17.2 10.7 29.3 15.9 20.6 14.2 19.2 13.3 7.8 8.0 10.8 15.1 12.0 15.6 13.8 8.9 9.0 11.5 9.6 11.8 9.3 11.7 19.2 14.2 9.6 26.7 12.7 14.8 18.4 13.6 10.9 14.8 13.9 7.6 12.7 13.5 11.7 12.3 13.3 15.8 15.5 18.1 11.6 31.6 11.8 70.6 15.0 13.3 20.1 16.5 16.5 14.7 11.8 23.4 12.4 15.5 16.3 9.2 22.3 6.6 27.8 15.0 6.2 7.5 15.4 21.5 14.7 26.8 29.3 11.1 10.9 40.4 15.6 12.0 24.0 13.0 22.7 14.8 37.5 20.2 16.4 33.2 22.9 11.6 6.8 35.5 16.8 4.0 9.7 24.2 18.3 7.3 12.6 27.5 24.0 35.3 18.8 10.0 36.3 13.7 24.4 13.4 13.7 34.5 47.1 25.0 10.0 16.7 28.7 16.1 24.3 19.9 23.5 19.4 11.4 21.7 8.7 20.7 22.5 30.2 30.1 14.0 19.5 46.4 14.0 28.4 18.5 17.4 9.5 23.4 12.6 9.6 16.3 14.7 15.0 12.7 11.4 10.7 14.3 11.9 16.9 15.5 12.4 11.8 13.6 9.2 11.3 10.7 20.6 14.2 11.5 9.6 14.2 9.6 10.9 11.8 44.7 25.6 45.4 30.6 55.3 44.0 29.7 20.4 56.2 43.3 15.7 21.6 30.6 16.6 26.4 117.0 37.9 12.9 0.0 29.7 56.2 38.1 45.1 26.6 15.8 26.9 33.4 8.1 23.4 28.2 52.6 46.3 31.1 25.3 53.3 29.2 47.5 22.4 7.0 38.5 13.5 78.0 51.8 47.7 281.4 214.8 56.2 27.6 46.5 30.4 28.8 USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699978-84779922 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 105.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "neutrophil: 105.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 105.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favorable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" 13.9 18.8 16.0 24.2 19.0 13.4 14.4 24.4 20.4 15.9 18.1 15.6 8.4 16.1 20.2 10.4 19.7 18.2 12.0 16.4 19.3 15.1 16.4 20.7 13.7 18.8 19.7 17.4 18.5 17.1 35.8 15.0 23.5 16.2 15.0 15.6 17.9 15.3 17.8 47.0 17.0 17.5 20.2 16.3 16.0 15.0 15.5 16.2 20.4 17.6 15.7 20.9 19.7 15.8 7.2 10.4 105.5 8.6 7.7 17.3 10.0 13.9 19.3 18.8 23.3 6.9 11.8 25.4 13.8 14.6 23.4 12.9 27.2 12.2 24.2 16.0 14.4 11.7 16.0 26.1 21.9 31.2 9.8 13.7 13.9 9.1 18.0 9.2 20.6 8.4 7.4 17.0 24.4 28.3 13.9 17.9 16.2 37.9 5.3 16.2 29.2 21.3 10.0 22.6 15.6 13.1 27.8 10.3 11.5 14.7 11.4 17.6 10.4 33.0 10.7 9.3 17.2 24.7 13.2 13.1 16.3 13.0 8.2 13.1 8.9 12.3 61.4 10.5 13.3 16.6 2.5 8.6 1.6 5.7 7.0 6.8 7.2 17.3 6.3 10.4 6.7 9.9 6.0 105.5 7.7 6.3 3.5 6.1 10.0 16.0 19.0 24.4 20.4 19.3 15.1 19.7 17.4 16.2 16.2 50.6 41.3 27.5 36.9 45.7 24.1 56.0 25.5 124.5 62.6 26.2 27.5 85.2 26.6 26.4 61.2 28.2 27.5 23.3 21.5 65.0 33.0 35.8 53.5 33.4 27.3 19.1 27.7 27.0 34.9 79.4 21.9 31.0 23.6 27.9 26.5 20.1 22.1 17.5 21.2 35.6 48.5 25.8 38.2 32.5 29.0 43.3 50.9 25.4 33.2 36.5 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232690-47248328 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 74.0" "Cell type enhanced" "Detected in all" 6 "Bipolar cells: 178.6;Horizontal cells: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA Nucleoplasm Cytosol "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favorable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 11.5 17.3 32.9 11.5 55.0 4.9 9.4 35.7 74.0 17.5 9.1 19.9 5.8 6.0 22.6 12.7 9.7 26.6 12.8 20.6 27.0 44.0 13.6 6.7 12.5 13.8 23.1 47.4 38.2 13.8 28.4 32.3 12.6 27.8 15.7 7.6 17.9 9.3 21.3 13.7 7.8 7.3 19.1 17.0 13.5 9.1 19.2 14.6 19.0 27.2 4.3 14.3 11.0 9.8 21.0 20.6 22.8 8.7 19.8 31.7 16.4 14.4 22.8 39.3 26.7 14.9 10.0 10.9 11.1 17.5 22.1 24.7 21.7 11.9 9.6 8.8 20.0 23.6 17.3 31.8 7.8 19.7 14.8 24.1 11.2 18.1 19.2 17.3 12.6 23.4 14.3 3.3 23.3 10.0 12.4 8.8 22.5 8.3 1.3 17.2 22.0 24.3 13.4 29.2 7.9 20.3 27.4 38.5 8.0 10.8 20.0 22.3 38.1 20.3 4.1 12.0 26.2 8.6 7.2 9.2 18.6 19.7 26.2 12.6 17.8 11.2 16.7 11.6 15.7 16.6 22.8 3.5 7.4 22.6 7.4 19.9 20.1 10.2 22.1 4.6 21.0 15.4 31.7 2.2 19.8 8.7 20.6 12.7 16.4 32.9 55.0 35.7 74.0 27.0 44.0 23.1 47.4 27.8 14.6 20.8 15.3 34.1 35.1 12.0 178.6 20.7 12.7 41.5 29.6 31.4 53.0 16.9 43.1 13.8 20.4 19.6 7.8 23.3 9.0 11.2 33.9 14.4 45.0 6.6 12.0 131.9 34.0 23.4 8.8 28.3 27.3 12.9 27.0 26.2 7.9 89.6 11.0 7.0 39.6 12.5 53.1 25.8 33.0 11.7 38.3 5.6 13.6 30.6 8.0 25.7 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066142-27171896 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 15.7 10.4 18.3 23.3 17.8 46.0 15.6 16.6 18.3 12.1 30.6 16.1 8.8 13.0 15.3 11.6 23.5 9.5 14.5 11.3 19.3 15.9 18.3 27.9 19.9 19.6 20.5 7.5 12.0 13.4 10.7 16.2 14.8 12.4 17.5 19.1 10.1 8.9 9.5 9.8 17.3 33.0 43.8 18.5 16.5 14.7 11.0 13.1 8.4 12.0 6.6 18.5 42.8 24.2 4.6 3.0 5.3 2.1 2.3 3.6 1.2 12.1 7.6 14.6 7.6 9.8 12.6 5.2 17.1 12.1 9.5 7.1 13.8 19.1 17.3 8.6 13.5 23.1 7.5 9.5 9.9 20.4 27.9 8.2 26.7 9.9 9.7 12.4 15.4 18.8 7.8 14.6 10.7 12.4 12.1 21.9 12.0 8.9 8.4 19.7 7.1 9.4 20.6 10.5 15.6 13.5 10.8 18.7 4.1 18.8 8.6 16.2 9.8 14.7 12.4 13.8 19.1 5.8 15.0 25.8 10.0 9.6 21.3 15.5 6.5 7.2 12.3 16.8 9.2 11.1 0.0 1.2 5.3 1.5 1.3 2.5 3.2 2.4 2.0 1.6 4.6 1.6 1.7 1.2 2.3 2.1 3.0 3.6 1.2 18.3 17.8 16.6 15.5 19.3 15.9 20.5 7.5 12.4 13.1 26.8 25.1 15.1 22.9 81.5 21.6 22.6 10.2 16.0 10.3 22.7 37.3 12.2 24.9 11.8 16.7 31.9 32.8 46.7 14.0 5.6 31.0 29.2 12.7 22.2 12.6 27.0 20.1 17.2 15.8 8.2 7.2 23.3 37.1 44.1 23.6 10.9 19.7 25.8 6.0 15.7 29.9 32.3 45.3 2.5 8.9 69.1 9.2 13.8 20.4 30.3 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179652755-179789401 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.8;skeletal muscle: 90.3" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 182.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "MAIT T-cell: 15.4" "Lineage enriched" "Detected in many" 8 "T-cells: 15.4" "Cell line enhanced" "Detected in many" "HDLM-2: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.06e-4)" 6.4 7.5 2.0 2.3 2.8 0.8 3.5 2.9 4.1 2.7 2.1 4.6 1.5 0.7 3.2 3.8 2.6 2.5 2.5 34.8 2.0 2.3 2.3 3.4 6.0 2.5 2.1 2.1 7.2 3.0 3.3 9.8 1.9 3.0 3.0 1.8 3.1 3.3 2.1 90.3 1.8 1.7 3.7 2.5 1.6 1.6 5.6 1.3 1.7 5.5 17.1 3.2 2.6 1.9 2.0 1.9 0.0 0.4 0.0 15.4 0.7 12.5 5.4 10.2 7.8 4.6 6.4 4.9 7.4 8.5 10.9 9.2 7.9 4.4 15.5 8.3 8.9 12.3 0.9 11.4 4.5 13.0 36.6 4.9 4.1 8.1 7.4 3.3 11.4 0.0 6.9 1.6 8.5 10.8 5.3 8.7 6.1 2.0 20.0 9.0 8.2 6.9 2.1 7.9 1.1 4.9 11.9 10.1 12.7 7.4 3.5 5.8 7.5 7.1 9.5 4.3 3.0 16.4 8.2 9.4 13.2 10.5 11.3 28.4 9.7 8.1 31.7 6.1 7.7 12.2 0.0 0.2 0.0 1.3 0.4 15.4 2.0 1.3 2.9 1.5 0.6 1.0 1.0 0.0 0.0 0.4 1.9 0.6 0.7 2.0 2.8 2.9 4.1 2.0 2.3 2.1 2.1 3.0 1.3 8.9 31.0 4.3 1.7 2.3 12.7 182.3 5.1 2.7 9.1 1.8 5.9 8.7 13.3 1.0 2.1 9.7 0.3 0.0 3.7 1.6 7.1 3.4 2.3 6.8 3.7 15.9 9.2 27.6 3.1 2.0 8.6 4.7 13.5 0.0 1.6 6.3 1.6 5.8 8.9 2.7 9.7 12.9 5.3 5.1 2.1 1.4 4.2 3.2 3.8 1.6 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 1400000 "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 24.8 24.2 25.9 20.7 32.1 19.4 21.7 21.7 28.4 16.5 17.1 17.9 19.1 13.4 19.4 24.3 25.3 14.7 14.4 23.3 22.1 27.6 23.2 24.4 15.8 21.9 22.6 28.8 16.2 16.2 22.3 18.0 25.1 29.2 29.9 19.4 14.5 16.7 20.5 53.3 15.7 12.9 23.9 22.1 15.4 15.6 17.2 16.5 19.5 20.1 25.4 28.6 17.8 17.8 13.1 15.2 7.7 15.2 23.0 21.2 11.0 27.1 22.3 19.0 19.3 18.8 18.8 34.0 35.7 19.5 36.3 34.0 29.0 14.5 40.3 27.3 29.2 34.9 15.3 37.4 27.2 41.4 11.4 18.5 22.7 15.0 22.7 18.9 55.7 21.8 15.0 21.1 37.1 21.3 16.8 27.9 19.9 31.2 29.9 35.8 22.0 31.1 15.2 18.5 16.3 26.2 25.9 24.9 29.3 26.8 23.6 22.2 18.6 37.0 17.9 15.2 21.6 17.5 15.1 31.5 42.7 32.3 39.2 50.5 19.8 35.9 40.0 24.6 23.3 26.5 5.0 10.7 7.7 17.8 15.2 21.2 13.1 17.7 18.4 15.2 10.1 17.5 16.9 0.8 23.0 11.4 11.1 16.7 11.0 25.9 32.1 21.7 27.1 22.1 27.6 22.6 28.8 29.2 16.5 20.8 33.1 28.2 36.7 52.1 52.7 40.0 22.9 42.8 51.2 41.8 29.5 80.1 38.1 58.5 41.3 39.3 15.4 23.3 46.8 58.4 42.1 56.1 33.5 39.4 45.0 109.7 21.2 28.3 30.4 14.7 29.4 39.1 33.7 54.1 19.4 35.6 58.1 19.5 43.2 43.1 50.1 0.0 45.7 26.2 61.2 45.8 113.4 38.8 27.3 39.1 USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 68.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Plasma membrane,Cytosol" NA NA 280000 Cytosol "Plasma membrane" "HPA006237: AB_1080502, HPA006428: AB_2667588, HPA071014: AB_2686333" "unprognostic (8.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.63e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (6.59e-2)" "unprognostic (7.70e-3)" "unprognostic (2.19e-1)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (9.28e-2)" "unprognostic (5.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.26e-1)" 23.1 16.8 11.5 22.5 11.9 88.9 17.8 21.1 15.7 14.5 14.5 5.2 11.9 11.4 12.7 12.4 16.1 14.1 11.2 15.2 9.6 6.2 13.8 20.4 23.8 26.2 11.6 9.4 22.5 15.8 18.9 22.5 31.0 14.9 12.4 13.8 7.6 16.2 10.7 28.5 23.0 19.7 16.3 16.2 35.6 14.3 20.0 11.0 33.1 14.1 15.4 18.9 18.4 17.9 5.7 6.0 68.5 14.2 3.3 12.1 4.8 9.4 8.9 8.9 7.8 14.1 16.5 16.0 15.4 13.7 13.6 12.2 8.9 9.5 10.1 8.8 13.2 5.8 10.4 11.9 13.4 16.0 11.2 7.3 13.9 7.6 6.8 13.6 22.0 33.8 12.0 14.0 16.1 14.3 12.8 16.2 10.3 45.0 19.6 12.6 10.5 13.1 11.1 13.0 8.6 13.2 8.4 9.4 16.3 12.7 10.9 11.3 5.4 17.8 11.3 8.7 9.7 15.0 13.2 19.3 10.6 10.6 16.5 9.5 9.3 10.4 11.6 12.2 17.9 12.0 27.2 14.2 13.8 3.4 7.3 3.5 5.7 4.6 3.2 4.9 4.7 5.9 3.5 68.5 3.3 5.8 6.0 12.1 4.8 11.5 11.9 21.1 15.7 9.6 6.2 11.6 9.4 14.9 11.0 35.7 31.3 91.0 32.3 52.2 54.5 62.7 17.8 42.8 59.1 22.7 104.1 25.1 10.0 31.3 139.8 44.6 32.3 93.5 36.2 36.1 49.5 31.6 85.6 42.0 41.1 39.7 40.4 22.1 108.1 130.5 57.2 94.6 50.6 36.1 22.9 24.4 41.2 45.6 27.6 19.4 146.4 38.8 56.5 62.9 41.8 67.2 55.0 65.0 23.3 54.9 USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Early spermatids: 399.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021140 Supported Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA021140: AB_1858668" "unprognostic (6.06e-2)" "unprognostic (3.14e-1)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (5.92e-2)" "unprognostic (5.79e-3)" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (5.78e-2)" "unprognostic (7.40e-2)" "unprognostic (8.73e-2)" "unprognostic (8.65e-2)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-1)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" 25.4 21.7 24.4 27.4 24.2 20.4 22.8 32.4 23.1 24.2 24.3 13.5 23.6 20.4 22.6 28.2 27.1 19.4 17.0 23.8 23.8 22.6 28.4 34.0 16.8 20.7 25.8 19.5 27.3 23.6 31.6 41.6 45.9 25.3 26.0 22.3 13.3 20.6 28.8 35.8 16.1 33.2 26.2 28.6 29.1 20.8 20.1 25.3 37.6 28.4 25.6 25.5 30.8 17.1 30.9 23.5 21.2 20.5 19.9 26.2 10.1 22.0 8.8 14.1 12.6 10.0 16.5 13.3 21.6 14.4 15.0 14.3 11.0 14.4 22.5 6.5 20.7 22.9 10.1 17.4 15.7 19.6 21.6 18.5 30.1 10.7 12.2 14.9 29.5 16.7 14.1 16.6 19.5 18.1 11.1 14.3 12.9 24.7 39.9 17.3 10.1 18.1 10.8 15.0 18.0 11.5 12.2 34.8 25.8 12.3 16.0 15.3 16.3 14.0 22.4 18.9 10.0 15.4 20.2 14.4 17.6 21.8 16.1 22.1 34.1 46.8 23.7 18.3 21.4 17.4 21.2 16.2 20.9 25.4 16.1 19.8 26.4 23.9 22.8 14.9 30.9 26.2 24.8 15.5 19.9 20.5 23.5 24.5 10.1 24.4 24.2 32.4 23.1 23.8 22.6 25.8 19.5 25.3 25.3 80.4 84.0 98.9 106.9 50.8 161.8 74.6 53.5 112.4 87.6 50.6 84.4 70.3 112.7 61.8 399.0 40.7 72.4 23.3 103.3 66.4 62.2 82.7 136.5 77.6 53.4 68.3 79.3 46.1 54.6 89.6 81.1 59.7 59.1 95.6 64.7 103.3 77.6 75.8 81.7 60.8 186.0 58.2 71.0 80.0 64.3 56.2 135.5 69.2 70.2 111.6 USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17-like family member 2" Q6R6M4 8 12137168-12139077 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEK 293: 1.3" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" "unprognostic (2.01e-1)" 0.1 0.4 0.1 0.1 0.5 0.0 0.2 0.8 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 1.0 1.1 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.2 0.0 0.5 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L22 ENSG00000248933 "Ubiquitin specific peptidase 17-like family member 22" D6RA61 4 9267619-9269570 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.0" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L24 ENSG00000232264 "Ubiquitin specific peptidase 17-like family member 24" Q0WX57 4 9325165-9327116 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L25 ENSG00000230430 "Ubiquitin specific peptidase 17-like family member 25" Q0WX57 4 9329911-9331862 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L26 ENSG00000229579 "Ubiquitin specific peptidase 17-like family member 26" Q0WX57 4 9334658-9336609 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L27 ENSG00000235780 "Ubiquitin specific peptidase 17-like family member 27" Q0WX57 4 9344148-9345740 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L28 ENSG00000231051 "Ubiquitin specific peptidase 17-like family member 28" Q0WX57 4 9348893-9350485 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L29 ENSG00000231637 "Ubiquitin specific peptidase 17-like family member 29" Q0WX57 4 9353638-9355230 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L30 ENSG00000228856 "Ubiquitin specific peptidase 17-like family member 30" Q0WX57 4 9363129-9364721 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L5 ENSG00000227140 "Ubiquitin specific peptidase 17-like family member 5" A8MUK1 4 9339403-9340995 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18149899-18177397 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Distal tubular cells: 39.7;Extravillous trophoblasts: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 48.9;BJ hTERT+ SV40 Large T+ RasG12V: 53.2" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA Cytosol Vesicles "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 20.4 6.4 4.8 13.0 4.8 6.3 15.4 1.9 5.5 5.3 6.3 5.6 3.2 5.2 6.1 9.5 6.0 6.5 7.1 5.4 4.4 4.6 8.8 20.9 14.0 15.9 4.3 4.8 4.9 4.2 3.8 7.8 7.6 4.7 4.8 3.9 5.7 11.7 2.3 9.7 4.2 15.5 4.5 4.1 10.6 6.4 10.6 4.0 22.4 10.6 2.9 7.7 4.3 6.9 4.1 2.9 6.6 8.8 11.0 11.0 4.8 3.7 3.8 1.1 4.9 5.0 3.7 5.0 1.9 4.6 48.9 53.2 0.6 5.3 0.0 3.0 1.0 15.6 1.3 5.7 1.7 1.6 16.7 7.9 7.3 0.5 6.9 0.6 1.7 7.0 1.6 0.6 3.4 0.0 0.2 10.8 5.5 0.3 0.4 0.4 6.4 8.5 4.3 3.4 4.0 2.9 3.4 7.6 0.0 0.9 3.2 4.1 3.2 2.3 4.0 18.2 4.6 2.7 1.7 17.7 0.3 1.0 1.1 1.9 0.9 11.4 0.0 4.4 4.4 2.8 2.7 3.2 6.6 7.8 8.8 10.0 4.1 6.7 10.1 1.6 2.7 7.9 8.8 0.5 11.0 6.6 2.9 11.0 4.8 4.8 4.8 1.9 4.0 4.4 4.6 4.3 4.8 4.7 4.0 8.9 3.7 0.5 3.7 1.4 0.2 0.4 5.1 8.1 6.8 0.0 0.0 4.5 39.7 5.1 1.2 6.0 4.3 0.0 9.9 27.4 3.1 3.8 0.0 4.3 7.7 0.0 2.9 9.2 4.5 1.4 3.4 1.8 3.3 0.0 2.2 3.9 9.2 2.9 6.7 5.7 0.2 6.5 1.2 6.2 0.4 0.9 1.3 1.5 2.8 2.5 USP19 "KIAA0891, ZMYND9" ENSG00000172046 "Ubiquitin specific peptidase 19" O94966 3 49108046-49120938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (3.23e-2)" "unprognostic (2.12e-1)" "unprognostic (5.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.00e-3)" "unprognostic (2.69e-1)" "unprognostic (3.65e-2)" "unprognostic (2.31e-2)" "unprognostic (1.26e-1)" "prognostic favorable (7.05e-9)" "unprognostic (2.99e-1)" "unprognostic (2.11e-1)" "unprognostic (1.72e-3)" "unprognostic (7.54e-2)" 13.9 19.5 10.3 14.6 12.2 16.2 14.9 19.4 37.1 17.0 16.3 12.5 19.6 14.6 18.7 17.9 14.3 17.2 19.9 17.9 10.3 9.4 14.8 16.5 14.7 13.8 11.9 9.5 17.2 15.2 22.4 13.2 17.6 11.4 14.2 10.9 14.9 24.7 26.0 57.3 18.4 16.1 13.9 8.5 17.5 15.1 14.9 11.7 23.0 17.7 15.2 12.6 17.4 14.1 5.1 6.7 12.3 5.7 4.3 8.4 5.3 8.3 12.0 14.4 20.3 17.7 12.2 18.4 9.4 12.6 17.6 13.3 12.0 12.8 18.0 9.6 11.8 17.5 11.1 18.2 13.6 7.3 14.1 14.0 17.5 24.1 11.0 18.4 19.8 18.5 17.3 10.6 16.6 12.1 12.3 11.5 16.1 13.7 13.6 8.8 10.8 18.7 20.5 27.3 12.5 17.6 9.1 10.7 20.8 10.9 15.9 7.9 22.7 13.9 18.2 16.3 12.5 12.3 26.4 9.1 11.7 14.3 17.3 14.2 34.4 33.3 15.9 15.1 15.7 14.5 12.3 4.9 7.5 7.2 5.3 6.8 4.6 5.8 8.4 6.7 5.1 5.7 6.2 8.8 4.3 5.7 3.0 4.1 5.3 10.3 12.2 19.4 37.1 10.3 9.4 11.9 9.5 11.4 11.7 11.9 9.7 2.9 4.0 5.6 11.4 9.6 2.5 10.7 10.3 7.0 17.7 8.5 5.0 6.6 2.7 7.1 13.1 0.0 6.7 4.4 5.8 4.6 2.3 12.1 7.8 12.7 8.7 7.4 6.1 4.1 12.0 8.4 3.3 1.8 11.3 7.7 9.8 11.8 11.7 6.3 11.2 12.9 5.2 10.5 10.0 4.6 11.3 6.4 10.9 2.6 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381726 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 79.9" "Group enriched" "Detected in many" 5 "Early spermatids: 399.1;Late spermatids: 802.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "naive CD4 T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enriched" "Detected in many" 4 "U-266/70: 35.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 3.1 4.8 6.9 1.4 12.2 1.5 1.6 12.6 16.1 2.5 5.9 10.0 0.0 7.9 2.6 6.4 5.9 7.0 2.2 26.8 5.7 3.1 29.7 10.6 2.2 0.7 5.7 6.2 2.9 10.1 18.4 7.6 1.3 6.7 2.3 3.9 19.1 3.2 2.4 79.9 4.6 11.7 4.2 3.8 0.8 2.7 36.1 8.8 0.0 2.2 25.2 1.0 1.9 2.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 3.5 0.3 0.5 2.0 0.1 0.1 0.8 0.4 0.2 0.0 0.4 3.6 0.5 6.1 1.1 0.6 0.9 0.6 4.8 1.8 0.1 4.2 0.6 1.7 2.6 7.5 1.7 0.0 1.7 0.6 0.3 0.4 1.2 0.8 0.3 4.6 8.4 0.5 1.0 2.4 0.0 0.4 0.9 1.2 0.8 0.0 1.3 0.9 2.8 0.2 7.4 2.2 2.1 1.6 0.4 1.1 5.4 3.7 0.0 0.0 0.9 0.5 0.6 35.2 7.7 0.1 0.0 1.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.0 0.3 0.3 6.9 12.2 12.6 16.1 5.7 3.1 5.7 6.2 6.7 8.8 3.0 2.4 0.0 4.5 2.2 73.3 74.6 5.1 42.8 9.1 5.2 90.3 0.3 96.2 2.6 399.1 2.2 31.5 0.0 1.4 0.5 4.6 1.0 0.0 19.8 13.2 9.5 0.0 1.3 1.5 802.9 6.1 1.3 0.0 0.0 1.6 37.9 1.5 10.5 6.7 24.9 128.7 19.4 18.6 19.9 14.9 3.4 1.1 1.5 2.2 2.0 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881838 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 42.3;K-562: 25.9;MOLT-4: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (2.48e-4)" "prognostic favorable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favorable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favorable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 7.8 13.2 10.5 15.2 14.6 24.4 8.5 23.0 19.6 13.2 12.1 12.7 10.2 9.7 13.3 6.2 9.3 11.6 12.5 8.8 10.5 13.7 8.0 7.3 9.1 19.6 9.6 16.1 16.8 12.9 11.5 19.0 8.0 11.9 14.9 6.1 10.8 13.7 17.2 10.2 14.0 11.8 20.0 8.8 14.6 10.2 14.0 8.8 51.5 19.3 4.2 15.3 15.6 10.0 3.8 2.4 4.8 1.7 9.0 10.7 5.4 2.5 2.5 4.4 6.0 5.8 5.0 6.3 4.1 3.5 3.2 2.2 2.1 2.8 3.5 3.6 4.0 3.6 6.5 2.6 3.0 1.3 19.0 3.5 6.5 6.8 1.4 4.1 6.1 4.8 4.4 4.4 4.2 3.1 5.6 3.4 42.3 25.9 4.4 1.9 6.8 23.8 14.5 3.5 5.4 6.0 4.0 5.0 5.9 2.5 2.8 1.0 4.9 4.8 6.2 3.9 2.7 6.4 8.5 5.0 3.5 1.6 4.7 2.7 4.3 6.3 2.4 7.0 8.0 3.3 1.0 1.7 4.8 8.6 1.4 9.3 3.7 8.8 8.3 2.4 3.8 10.4 8.9 2.8 9.0 1.3 2.1 10.7 5.4 10.5 14.6 23.0 19.6 10.5 13.7 9.6 16.1 11.9 8.8 8.9 8.6 3.2 2.3 2.5 7.9 5.9 2.5 4.0 2.3 1.8 3.9 5.1 3.3 2.2 1.1 2.4 4.0 0.0 3.4 2.1 3.8 3.0 1.1 5.6 3.0 9.5 8.1 7.4 2.1 2.8 5.8 3.1 3.3 3.6 4.6 5.8 2.3 3.7 4.6 2.2 5.9 0.0 6.2 12.2 4.4 1.8 5.1 11.3 5.1 1.4 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favorable (3.35e-5)" 11.8 16.4 22.1 12.8 21.2 15.3 19.1 23.6 24.8 18.1 16.1 25.5 14.0 15.5 19.7 14.6 18.3 33.3 14.1 13.7 20.9 12.1 15.4 10.6 14.0 16.7 26.4 14.1 28.3 19.0 24.4 17.2 15.2 20.5 18.1 13.1 17.1 19.0 25.3 19.4 23.5 15.4 15.1 17.0 18.7 16.0 17.0 22.9 16.0 24.5 9.6 15.6 17.9 19.2 14.1 12.0 18.3 11.1 13.4 17.2 10.7 7.4 12.9 16.9 16.3 13.5 11.3 10.4 5.5 9.0 15.2 11.9 11.8 14.7 9.8 9.5 6.8 9.5 12.9 10.9 10.7 8.4 18.6 18.4 11.6 18.6 9.2 9.8 10.3 8.7 9.5 14.4 10.4 15.1 17.2 10.7 21.7 17.2 13.6 9.7 13.7 18.2 16.2 15.8 14.6 16.4 17.3 5.6 16.4 8.9 8.9 15.4 19.9 10.3 10.9 8.3 13.2 23.9 16.7 6.3 10.9 9.8 7.6 9.4 27.6 21.3 14.5 10.0 8.9 9.8 13.0 11.1 18.3 14.9 7.1 17.2 12.8 13.8 15.4 12.0 14.1 16.0 14.6 9.6 13.4 7.7 12.0 13.3 10.7 22.1 21.2 23.6 24.8 20.9 12.1 26.4 14.1 20.5 22.9 0.0 3.0 1.7 1.5 1.3 3.9 2.2 10.2 10.7 3.4 1.8 5.9 3.6 1.7 1.4 0.6 2.8 2.0 0.0 2.0 2.1 2.4 2.0 2.3 1.7 1.9 0.0 5.2 6.2 7.6 0.4 4.6 1.7 1.7 0.0 4.1 3.0 1.7 2.9 3.9 1.8 4.4 6.5 1.9 3.6 2.7 1.3 2.6 2.5 3.7 1.4 USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999593-21043760 "Enzymes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA044980: AB_10794503" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (7.67e-2)" "unprognostic (6.19e-2)" "unprognostic (4.72e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.17e-2)" "unprognostic (7.81e-2)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (5.68e-2)" "prognostic favorable (1.53e-7)" "unprognostic (8.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-2)" 22.5 33.0 40.7 21.5 49.5 25.9 24.6 66.1 66.4 26.8 23.6 31.9 25.1 18.9 36.7 29.3 21.9 33.9 23.0 44.1 38.7 47.6 27.7 22.9 26.1 25.1 31.0 40.7 45.6 24.5 47.4 32.2 22.4 35.1 27.5 20.5 28.7 20.0 29.5 47.6 22.1 21.1 31.2 24.8 23.7 22.7 20.2 23.7 41.2 32.8 24.8 27.3 25.1 23.2 13.7 12.1 13.4 13.3 8.9 15.5 6.9 19.6 35.6 34.6 29.7 20.2 21.0 16.5 22.6 17.4 20.4 17.4 41.0 8.9 26.9 21.8 34.7 13.8 21.1 33.5 27.0 30.6 12.8 23.2 22.3 23.7 19.9 24.0 24.5 19.5 23.1 16.2 23.1 24.3 23.3 25.4 17.7 25.3 9.8 28.8 20.2 34.3 11.7 17.8 23.3 11.7 38.0 54.8 18.3 18.8 28.9 16.7 34.4 29.2 12.1 23.7 99.0 20.3 14.5 32.2 20.9 27.8 21.4 30.5 10.5 14.1 89.5 21.2 13.1 32.2 6.8 13.3 12.6 11.0 9.8 11.1 10.9 11.7 10.9 12.1 13.7 15.5 14.6 13.4 8.9 12.2 10.2 7.8 6.9 40.7 49.5 66.1 66.4 38.7 47.6 31.0 40.7 35.1 23.7 38.7 45.6 40.4 39.5 29.3 90.6 20.9 58.6 29.4 35.2 57.6 88.4 42.1 19.9 47.1 31.0 40.9 35.1 0.0 50.6 33.9 44.7 49.2 29.0 55.2 34.1 111.2 84.7 78.0 53.0 39.2 47.2 23.7 33.7 24.4 42.7 58.7 59.0 38.6 67.5 45.1 54.5 12.9 38.8 14.2 16.6 25.5 55.0 23.0 46.6 38.9 USP24 KIAA1057 ENSG00000162402 "Ubiquitin specific peptidase 24" Q9UPU5 1 55066359-55215113 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.0" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026723, HPA028428, HPA067124" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA026723: AB_10599851, HPA028428: AB_10600991, HPA067124: AB_2685785" "unprognostic (2.28e-1)" "unprognostic (9.81e-3)" "unprognostic (4.70e-3)" "unprognostic (4.86e-3)" "unprognostic (9.31e-3)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.34e-7)" "unprognostic (2.04e-1)" "unprognostic (6.93e-2)" "unprognostic (2.98e-1)" "unprognostic (5.08e-2)" "unprognostic (1.86e-1)" "unprognostic (8.12e-2)" "unprognostic (1.79e-1)" "unprognostic (6.42e-2)" "unprognostic (4.12e-2)" "unprognostic (1.64e-1)" 12.3 7.6 7.5 12.1 8.8 30.1 10.6 20.1 8.5 7.8 10.2 6.8 10.6 5.0 10.1 7.0 7.7 6.9 7.0 14.7 7.9 6.4 10.4 9.3 7.6 12.7 8.0 5.6 10.9 7.3 15.5 16.9 5.8 6.9 7.6 8.5 5.1 9.7 10.7 46.0 8.9 8.7 7.3 6.2 10.9 7.8 4.9 8.7 16.4 7.4 11.5 12.7 9.7 13.7 6.0 10.5 5.9 2.2 3.8 4.5 1.1 17.7 9.8 12.3 6.6 16.0 14.1 14.2 7.9 9.9 11.4 11.9 13.9 6.3 14.3 8.7 14.6 23.4 14.4 16.3 13.3 17.9 14.9 9.8 28.6 21.4 16.3 9.5 19.7 22.2 12.3 11.8 17.2 19.6 11.0 10.3 14.6 26.3 6.0 15.1 4.2 11.8 10.5 18.0 8.6 11.9 12.3 15.7 6.2 19.8 12.0 10.8 7.6 13.4 9.6 11.7 19.5 6.7 9.8 13.9 10.4 10.1 12.5 12.5 7.6 5.6 18.8 9.9 16.4 9.3 5.9 2.0 2.5 4.5 1.8 2.8 4.8 3.5 3.5 1.8 6.0 3.2 4.2 2.3 3.8 2.2 10.5 1.9 1.1 7.5 8.8 20.1 8.5 7.9 6.4 8.0 5.6 6.9 8.7 14.9 18.3 14.2 7.0 13.3 12.9 28.1 10.2 8.1 15.9 12.2 68.7 3.6 0.0 8.8 0.4 13.1 6.8 0.0 8.7 6.5 9.6 9.6 12.7 10.9 8.4 36.5 16.6 10.4 17.5 1.3 10.9 12.2 10.1 12.6 16.4 7.1 9.9 11.5 7.4 4.5 16.7 6.5 10.5 8.6 5.8 15.1 1.3 17.1 14.9 8.6 USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15730025-15880069 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 124.6;Late spermatids: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol NA NA Cytosol "HPA018297: AB_1858672, HPA024142: AB_1858673" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (6.90e-2)" "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "unprognostic (1.40e-1)" "unprognostic (8.24e-3)" "unprognostic (2.34e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-2)" 14.9 8.5 11.0 14.2 15.5 12.4 28.7 11.3 11.1 17.5 11.8 6.6 17.8 6.5 20.7 14.5 12.6 10.6 10.1 17.8 9.9 5.8 12.9 10.4 22.1 14.8 7.6 7.1 14.5 8.2 8.1 8.4 17.7 7.7 12.9 8.6 7.8 11.4 13.6 56.3 8.3 12.3 19.2 7.3 11.6 9.0 26.1 7.5 16.5 10.5 14.6 9.6 13.8 18.1 3.1 2.8 5.8 2.9 2.3 7.2 1.6 13.2 10.0 9.5 1.4 17.6 26.3 11.2 9.5 9.5 7.1 9.0 8.8 7.6 14.3 14.1 15.0 10.8 7.1 7.3 12.6 9.9 14.2 8.4 11.7 10.6 6.7 29.2 15.4 5.4 17.0 15.4 11.4 33.2 18.7 24.9 13.1 15.0 27.1 12.8 5.5 17.6 2.9 11.7 5.3 8.9 13.5 8.8 10.8 19.3 3.6 2.1 5.7 13.6 11.5 8.8 12.1 6.1 9.1 23.6 11.1 7.2 11.6 5.3 7.9 4.8 11.4 7.2 6.9 8.1 0.0 2.9 3.6 4.0 2.8 4.4 3.1 3.4 7.2 2.5 2.2 3.2 4.8 5.8 2.3 2.5 2.8 4.4 1.6 11.0 15.5 11.3 11.1 9.9 5.8 7.6 7.1 7.7 7.5 53.6 22.7 11.5 16.1 15.1 5.7 52.1 10.2 25.4 31.8 21.0 3.9 27.3 5.0 7.8 124.6 19.1 12.8 0.0 11.4 6.8 16.0 19.0 5.8 17.3 11.9 4.8 9.2 17.2 23.7 145.9 17.5 18.8 15.1 6.4 11.9 4.2 10.4 7.0 12.0 12.2 6.0 19.4 15.5 9.8 5.3 16.8 27.7 17.5 10.2 20.5 USP26 ENSG00000134588 "Ubiquitin specific peptidase 26" Q9BXU7 X 133024631-133097109 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 3.8" "Cell type enriched" "Detected in single" 14 "Spermatogonia: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "HPA000424, HPA027310" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA000424: , HPA027310: " "unprognostic (7.92e-4)" "unprognostic (3.59e-2)" "unprognostic (1.99e-2)" "unprognostic (2.08e-1)" 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.1 0.1 3.8 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.0 0.0 0.5 0.4 0.5 0.4 0.1 0.1 0.2 0.2 0.7 0.1 0.2 0.1 0.7 0.1 0.1 0.0 0.1 0.7 0.1 0.2 0.3 1.0 0.3 1.0 0.3 0.1 0.1 0.0 1.5 0.6 0.4 0.1 0.3 0.1 0.4 0.4 0.4 0.2 0.2 0.1 0.8 0.4 0.2 0.3 0.4 0.1 0.0 0.9 0.5 0.5 0.2 0.1 0.1 0.2 1.0 0.1 0.7 0.3 0.9 0.1 0.3 0.4 0.9 0.3 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.7 0.0 0.0 0.0 0.0 0.0 USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27, X-linked" A6NNY8 X 49879948-49882565 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 17.9;Ciliated cells: 24.1;Cytotrophoblasts: 34.3;Syncytiotrophoblasts: 21.9" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA077264: AB_2686831" "unprognostic (4.12e-2)" "unprognostic (9.58e-3)" "unprognostic (2.29e-1)" "unprognostic (4.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.14e-4)" "unprognostic (3.10e-3)" "unprognostic (3.91e-2)" "unprognostic (1.31e-2)" "prognostic favorable (9.31e-4)" "unprognostic (5.37e-2)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-1)" 1.8 3.3 1.8 5.9 2.9 0.3 7.7 1.7 7.4 3.9 5.9 4.8 2.2 1.1 12.7 4.1 3.1 4.7 3.8 3.9 2.2 3.5 3.5 6.1 1.9 1.3 3.2 8.8 3.2 4.1 0.8 15.5 2.8 4.1 1.7 4.1 5.2 3.9 7.5 2.6 4.7 3.9 1.3 2.0 1.9 3.8 1.9 2.8 3.2 3.6 2.2 3.7 3.1 1.7 1.0 0.7 0.7 0.3 1.3 0.4 1.8 4.7 5.5 6.3 5.2 4.3 4.6 2.1 3.4 2.4 2.0 8.5 2.1 1.2 2.0 5.4 7.9 3.0 7.8 5.2 3.5 2.4 3.7 2.0 1.4 7.7 3.5 0.6 4.3 6.0 3.6 3.4 3.4 5.9 3.3 5.5 3.9 2.0 3.8 4.5 2.9 1.7 6.0 3.5 3.3 3.1 4.8 0.4 3.9 1.8 1.4 4.1 4.0 3.8 4.9 17.9 4.4 1.4 2.5 2.8 5.4 4.8 0.8 1.9 0.5 0.8 3.2 1.7 3.0 0.7 0.4 0.1 0.6 0.4 0.8 0.6 0.5 0.3 1.0 1.7 0.8 0.6 0.7 0.3 0.7 0.4 1.3 0.4 17.9 13.3 0.0 4.1 2.6 9.7 2.3 0.0 24.1 13.6 0.0 0.0 34.3 5.0 1.1 0.0 3.1 0.7 0.0 0.6 2.0 1.8 2.5 2.3 1.7 3.4 4.8 4.1 3.1 0.3 0.0 2.0 1.1 0.0 1.0 1.2 10.2 1.2 0.0 3.2 2.6 2.0 6.5 1.7 0.0 1.4 1.9 21.9 1.3 1.7 1.7 USP28 KIAA1515 ENSG00000048028 "Ubiquitin specific peptidase 28" Q96RU2 11 113797874-113875570 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 40.1;skeletal muscle: 50.2" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006778, HPA006779" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA006778: AB_1080520, HPA006779: AB_1080517" "unprognostic (2.54e-1)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" "unprognostic (3.72e-2)" "unprognostic (5.51e-2)" "unprognostic (2.30e-1)" "unprognostic (9.73e-3)" "unprognostic (3.00e-1)" "unprognostic (2.04e-3)" "unprognostic (1.82e-3)" "unprognostic (3.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.11e-2)" "unprognostic (2.06e-2)" "unprognostic (9.03e-2)" "unprognostic (1.35e-3)" "unprognostic (5.03e-2)" 3.9 3.4 4.8 8.6 5.7 2.4 5.7 26.4 8.6 11.6 5.1 4.9 14.0 4.7 6.0 6.0 5.7 5.0 4.0 40.1 5.0 4.8 5.1 5.6 5.1 7.2 6.8 4.5 7.5 4.1 10.6 9.7 3.9 4.8 8.9 6.0 5.7 5.7 12.2 50.2 3.5 5.1 11.6 6.4 6.9 4.4 5.5 3.8 3.6 5.1 10.1 7.7 7.1 4.6 10.3 4.1 2.1 3.7 17.9 16.2 6.0 8.6 9.7 13.1 17.3 10.8 10.7 9.3 6.4 8.8 8.6 14.8 14.4 12.5 11.5 14.6 8.6 19.9 17.0 18.5 12.0 12.0 12.8 8.4 6.1 6.8 7.7 6.6 7.8 6.1 6.4 9.1 10.0 11.9 12.6 15.5 5.7 10.5 7.5 9.0 4.4 5.9 12.8 15.7 16.0 7.0 14.7 18.3 13.9 9.5 8.5 5.7 6.2 15.2 5.2 4.9 42.9 12.6 2.7 8.2 9.6 14.4 8.7 6.5 5.1 7.3 9.7 0.9 15.3 6.2 0.1 3.2 2.1 16.2 2.4 8.4 10.3 4.1 11.4 4.1 8.4 2.7 9.4 0.9 17.9 3.7 1.2 5.6 6.0 4.8 5.7 26.4 8.6 5.0 4.8 6.8 4.5 4.8 3.8 8.9 9.1 10.0 6.9 1.4 16.1 130.6 5.1 14.7 10.3 5.2 17.7 3.5 5.0 5.7 1.4 4.3 5.1 0.0 3.4 3.7 4.7 6.2 1.1 6.7 3.9 4.8 4.7 6.2 4.1 1.4 6.4 6.5 1.7 5.4 10.3 10.1 4.4 3.5 13.1 6.3 20.2 6.5 5.2 10.8 10.0 1.8 0.9 24.5 9.2 4.9 USP29 ENSG00000131864 "Ubiquitin specific peptidase 29" Q9HBJ7 19 57119138-57131926 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "blood: 4.1;bone marrow: 2.7;pancreas: 2.1;skin 1: 2.3;testis: 8.4" "Group enriched" "Detected in some" 9 "Collecting duct cells: 1.8;Early spermatids: 1.7;Spermatocytes: 4.8;Spermatogonia: 1.5" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.2" "Not detected" "Not detected" HPA076515 Enhanced NA NA "HPA076515: " "unprognostic (1.32e-1)" 0.1 0.1 0.2 0.0 0.2 2.7 0.1 0.1 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.2 0.1 0.1 0.1 0.3 0.1 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.2 2.3 0.1 0.0 0.1 0.1 0.4 8.4 0.4 0.0 0.7 0.1 1.1 1.9 4.1 1.1 1.2 0.8 0.6 0.1 0.7 0.8 0.3 0.0 0.0 3.3 0.0 0.0 0.1 0.1 1.7 0.0 0.9 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.0 3.2 0.8 0.0 0.0 1.1 0.0 2.0 0.9 1.0 1.4 0.0 0.0 0.0 1.0 0.3 0.9 0.0 0.7 0.0 1.2 0.0 0.5 1.0 0.9 0.0 1.0 0.0 2.1 2.1 0.7 0.6 0.4 0.3 1.2 0.8 1.3 1.5 1.3 0.5 0.0 0.0 1.6 0.5 1.5 0.5 0.8 0.0 3.1 1.1 1.1 0.8 0.7 0.6 0.5 0.7 0.3 0.3 1.1 0.7 0.7 4.1 1.2 0.4 1.9 0.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.5 0.0 0.0 0.0 0.0 0.1 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 33.4" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" No No Nucleoplasm "Midbody ring" "HPA053275: AB_2682096, HPA060513: AB_2684299, HPA077975: AB_2732365" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.38e-4)" 16.0 9.0 5.9 20.4 6.5 38.6 21.3 33.4 6.6 12.7 19.1 6.0 16.8 16.2 18.1 13.3 13.6 10.4 14.2 7.6 6.6 4.4 12.9 10.8 17.5 28.2 8.1 3.9 19.5 27.1 7.1 8.2 10.2 7.9 12.4 11.5 8.2 18.5 14.8 12.4 15.9 19.0 16.1 8.0 23.6 14.7 10.3 7.8 22.7 12.5 11.4 22.5 21.3 17.9 11.4 20.6 52.6 28.1 7.2 12.9 13.4 9.2 30.2 15.6 9.8 7.7 12.6 13.8 7.9 9.9 7.7 9.5 11.8 17.3 9.4 12.6 7.9 5.1 11.7 14.6 12.3 7.5 15.3 7.9 10.6 10.8 12.7 6.6 6.3 12.8 9.0 16.3 9.3 16.2 7.8 16.7 16.9 14.1 12.0 4.9 14.3 13.1 10.2 19.7 18.9 13.1 19.2 9.4 16.6 9.2 31.7 13.7 10.6 4.9 16.2 9.7 8.9 9.7 12.3 15.8 8.9 18.6 5.2 10.5 10.8 19.9 20.8 8.6 17.5 7.4 28.8 28.1 3.5 8.4 22.6 9.3 10.3 11.9 8.6 20.6 11.4 12.9 9.3 52.6 7.2 18.7 4.1 9.1 13.4 5.9 6.5 33.4 6.6 6.6 4.4 8.1 3.9 7.9 7.8 35.7 60.4 35.8 31.2 46.8 31.1 9.1 20.4 36.1 43.3 15.7 11.8 17.3 34.9 36.4 19.7 20.3 33.9 0.0 32.3 46.8 16.4 35.8 25.5 20.8 22.8 12.7 42.1 11.1 75.5 53.6 14.7 64.4 40.5 27.1 32.5 24.6 35.0 31.7 17.3 19.9 17.8 12.9 25.2 10.2 41.8 51.6 28.5 37.4 34.7 33.1 USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088026 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved NA NA "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favorable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" 11.7 18.9 12.7 9.0 17.6 12.2 10.4 11.9 21.0 10.3 13.2 29.2 13.6 14.9 12.4 8.5 9.2 11.1 8.4 9.0 10.3 10.6 12.4 21.7 8.9 10.4 16.6 7.8 17.5 12.4 14.7 13.0 6.7 16.0 9.4 11.3 16.4 10.1 12.4 16.4 13.6 14.1 8.6 14.3 9.8 8.5 21.3 16.3 8.7 11.1 5.3 7.1 10.8 8.1 14.2 12.2 12.7 11.0 18.3 17.4 6.0 4.6 3.6 9.5 8.2 6.7 7.7 5.3 5.2 6.8 6.1 5.4 4.2 3.6 11.7 4.4 5.1 5.6 5.2 8.3 5.4 7.0 13.5 10.4 3.8 3.2 6.0 7.2 7.4 4.2 9.2 6.6 5.4 5.3 15.8 7.0 12.1 5.6 5.7 5.1 5.4 11.7 4.2 3.0 5.6 10.1 12.7 6.8 7.0 4.9 5.6 8.7 7.7 7.0 5.3 5.5 7.3 13.1 5.8 5.0 5.6 3.1 5.4 3.4 14.3 11.9 17.5 6.0 4.5 6.2 9.5 7.1 12.7 15.4 11.0 17.4 14.2 12.9 14.3 4.6 14.2 13.7 12.6 4.2 18.3 8.8 12.2 11.2 6.0 12.7 17.6 11.9 21.0 10.3 10.6 16.6 7.8 16.0 16.3 0.0 2.9 0.8 2.3 1.8 7.7 6.4 10.2 4.0 5.7 5.2 7.9 4.9 0.0 3.9 22.7 2.9 9.7 0.0 4.9 3.5 3.3 2.0 0.0 13.9 4.9 6.4 6.4 1.8 4.6 37.3 3.4 1.4 1.7 1.0 10.2 6.5 4.6 3.5 3.5 5.1 14.1 12.9 2.1 16.9 5.3 2.9 6.1 1.9 10.4 2.6 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Basal glandular cells: 55.8;Basal keratinocytes: 59.3;Spermatogonia: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol NA NA Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 6.3 5.3 11.2 4.0 16.6 7.1 8.7 12.7 16.5 10.9 4.9 19.7 2.6 3.7 15.3 7.7 9.3 6.5 4.1 11.0 9.0 6.3 6.2 7.7 7.3 3.6 24.6 8.1 3.7 6.3 20.6 10.4 7.4 17.4 9.6 4.9 2.8 6.0 8.5 10.9 15.9 3.4 14.2 14.8 2.8 3.5 20.7 19.3 1.7 4.2 2.4 4.9 13.4 9.5 0.5 0.8 0.6 1.3 0.1 2.1 0.2 9.5 10.1 2.9 4.0 5.3 4.2 2.7 3.3 3.0 4.3 5.2 6.4 5.8 3.2 3.6 4.2 7.0 12.6 7.2 13.1 7.1 2.3 2.9 1.3 5.8 13.4 6.7 3.3 3.6 3.5 11.3 8.0 18.5 1.6 7.6 3.2 3.9 10.0 5.8 6.5 1.6 2.8 5.8 3.2 3.1 7.9 8.2 6.4 6.4 14.3 7.8 5.1 5.2 10.3 2.9 3.4 4.1 7.4 4.5 8.8 6.5 4.4 9.0 3.3 5.4 3.4 6.3 4.5 3.5 0.1 0.7 0.6 0.8 0.3 2.1 0.1 0.7 1.5 0.8 0.5 0.8 0.8 0.1 0.1 1.3 0.2 1.3 0.2 11.2 16.6 12.7 16.5 9.0 6.3 24.6 8.1 17.4 19.3 6.0 3.0 6.1 55.8 59.3 12.6 9.2 10.2 8.1 7.9 5.2 2.0 11.1 0.0 6.1 3.6 14.6 1.4 0.0 7.2 6.2 5.4 14.2 1.1 25.0 4.2 0.0 4.6 7.4 3.1 8.9 7.2 2.9 6.8 1.0 3.5 4.8 7.6 0.0 4.2 9.1 7.4 19.4 7.1 23.8 60.3 23.2 6.3 1.3 5.2 19.5 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60179094-60422470 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 58.4" "Cell type enhanced" "Detected in all" 11 "Cone photoreceptor cells: 227.8;Rod photoreceptor cells: 128.6;Spermatocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 28.4" "Group enriched" "Detected in many" 10 "dendritic cells: 28.4;granulocytes: 13.5" "Cell line enhanced" "Detected in all" "MCF7: 61.6" HPA044365 Approved Approved "Golgi apparatus,Cytosol" NA NA "Golgi apparatus" Cytosol "HPA044365: AB_2678914" "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 9.5 13.9 17.3 10.8 19.5 20.6 10.9 14.6 20.3 8.0 8.5 18.9 7.9 7.2 8.2 5.4 13.1 7.4 9.1 11.1 14.7 12.2 15.5 19.7 12.5 8.6 18.8 14.3 7.4 8.5 17.3 11.4 9.8 19.2 8.7 8.9 11.6 8.2 9.0 23.0 12.2 7.2 9.8 16.5 12.1 8.1 58.4 18.1 7.3 15.6 7.9 8.5 8.8 8.5 1.4 28.4 13.5 2.1 0.6 1.1 0.9 11.1 12.7 6.8 10.8 17.2 16.2 6.4 9.1 13.8 12.0 15.4 6.6 7.3 6.9 7.7 16.8 19.3 5.9 11.5 12.6 21.2 5.2 5.1 13.8 10.1 7.2 17.1 10.9 12.6 15.1 9.3 16.1 14.9 12.4 13.1 8.3 13.9 5.7 14.8 61.6 11.0 7.7 7.9 10.7 6.1 5.3 17.9 4.1 12.6 8.1 4.8 7.2 7.6 2.2 11.7 12.3 9.4 15.2 11.0 18.2 19.0 11.4 8.5 5.9 11.2 6.5 9.1 8.6 11.8 4.3 2.1 7.2 1.0 1.8 0.7 1.4 0.7 0.8 4.1 1.1 0.5 1.0 13.5 0.6 2.0 28.4 1.1 0.9 17.3 19.5 14.6 20.3 14.7 12.2 18.8 14.3 19.2 18.1 6.0 13.1 7.7 11.6 23.9 16.9 7.6 5.1 6.7 13.6 5.2 227.8 4.3 3.3 9.0 69.1 8.4 6.8 23.3 6.3 5.3 10.4 9.3 11.5 10.6 16.5 12.7 7.9 9.2 33.2 25.6 12.0 27.7 5.0 14.4 4.2 10.3 8.4 9.1 5.3 3.7 128.6 25.8 9.5 100.3 9.1 19.2 4.1 12.9 4.4 7.1 USP33 "KIAA1097, VDU1" ENSG00000077254 "Ubiquitin specific peptidase 33" Q8TEY7 1 77695987-77759852 "Enzymes, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005719 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Nucleoplasm, Golgi apparatus" "HPA005719: AB_10601708" "unprognostic (2.31e-3)" "unprognostic (2.73e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (9.19e-3)" "unprognostic (1.88e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.59e-1)" "unprognostic (5.36e-3)" "unprognostic (4.89e-2)" "unprognostic (5.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" 30.8 27.1 28.1 18.8 32.1 24.6 28.6 55.3 37.5 21.6 20.4 20.6 18.5 20.2 23.3 23.0 17.8 19.2 21.7 17.0 30.7 30.6 26.0 20.3 21.0 20.7 26.0 25.4 25.3 17.0 28.8 23.4 34.6 38.7 24.6 21.0 21.4 19.5 19.8 16.3 19.4 23.8 19.8 21.4 22.3 19.5 19.9 21.6 27.8 25.1 12.9 20.3 21.0 20.0 15.7 12.2 33.2 18.4 12.3 17.8 10.6 16.1 7.4 25.6 17.7 36.9 32.3 22.0 17.7 16.9 21.6 24.3 9.8 14.0 12.1 16.8 17.2 35.5 12.8 18.6 12.1 26.6 11.1 14.5 42.7 18.1 8.5 23.0 14.5 10.8 23.7 9.5 20.9 15.4 20.9 19.2 11.1 16.6 10.6 16.2 6.2 13.1 14.5 24.7 12.6 14.7 12.6 27.0 8.5 20.4 16.6 21.5 16.6 12.4 16.5 24.7 22.8 9.2 15.8 16.1 20.0 14.2 20.1 16.7 8.7 11.0 11.8 15.1 17.2 10.1 33.2 15.4 20.0 15.1 15.0 15.3 13.4 14.7 15.2 11.5 15.7 17.8 15.6 20.9 12.3 18.4 12.2 13.2 10.6 28.1 32.1 55.3 37.5 30.7 30.6 26.0 25.4 38.7 21.6 41.7 36.3 21.6 16.5 15.2 50.9 31.5 20.4 36.1 25.0 33.2 55.0 21.0 8.3 16.9 2.8 26.4 26.8 0.0 13.4 15.9 21.2 23.9 22.0 18.1 16.5 58.8 34.1 28.8 33.6 3.6 33.1 22.3 21.9 19.8 26.0 34.5 15.7 28.6 30.1 19.2 40.3 19.4 17.5 36.1 26.3 14.3 10.0 27.5 22.9 20.0 USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61470769 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025815, HPA070764" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA025815: AB_1858681, HPA070764: AB_2686308" "unprognostic (4.04e-2)" "unprognostic (8.21e-3)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (8.91e-2)" "unprognostic (4.62e-2)" "unprognostic (9.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (7.01e-2)" 17.2 19.6 31.8 37.2 25.6 24.8 28.3 77.1 35.5 22.5 22.7 14.4 31.1 11.4 22.2 44.5 18.6 17.5 20.0 16.9 30.5 24.0 20.5 21.5 29.7 34.2 22.0 21.2 24.7 17.2 33.5 40.3 13.4 22.0 22.7 21.5 21.2 16.9 45.2 27.0 31.6 21.0 22.7 20.8 24.8 19.3 26.4 25.3 21.7 23.2 13.9 33.5 19.1 16.7 6.0 5.8 3.4 4.6 5.2 7.5 2.3 16.8 12.1 15.7 16.3 29.9 20.1 13.2 10.4 14.7 9.3 8.9 16.9 6.5 40.0 11.1 22.4 9.9 9.3 12.4 13.7 17.4 14.3 9.8 24.2 11.7 27.2 25.2 17.9 15.4 21.9 17.8 17.0 25.4 22.8 19.6 11.4 16.5 13.0 20.7 15.8 11.8 26.1 10.6 17.2 9.6 12.7 19.2 10.7 27.5 20.7 13.0 13.9 16.4 12.2 17.9 21.0 6.4 13.0 17.5 14.8 19.7 8.7 13.6 15.1 7.4 42.0 13.9 16.7 12.6 3.4 2.0 2.8 7.5 2.2 6.7 5.1 5.1 5.5 1.8 6.0 5.8 7.5 3.4 5.2 4.6 5.8 4.5 2.3 31.8 25.6 77.1 35.5 30.5 24.0 22.0 21.2 22.0 25.3 59.6 60.6 35.3 50.1 54.3 132.9 41.8 56.0 33.5 59.1 31.4 235.6 26.6 8.3 35.4 108.3 51.2 38.6 0.0 29.1 19.8 45.2 63.1 31.2 36.3 19.7 101.7 46.7 23.4 40.3 105.2 52.6 41.4 38.8 30.7 32.2 62.5 38.7 38.4 62.9 18.3 185.3 25.8 46.7 97.9 106.7 53.6 44.6 40.8 31.2 57.6 USP35 KIAA1372 ENSG00000118369 "Ubiquitin specific peptidase 35" Q9P2H5 11 78188812-78214711 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 32.4" "Group enriched" "Detected in many" 4 "Early spermatids: 20.7;Late spermatids: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "eosinophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055213, HPA058592" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" Nucleoplasm "HPA055213: AB_2682740, HPA058592: AB_2683766" "unprognostic (6.69e-2)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.57e-2)" "unprognostic (3.84e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (1.29e-3)" "unprognostic (2.93e-1)" "unprognostic (1.31e-1)" "unprognostic (4.38e-2)" "unprognostic (1.49e-2)" 4.9 17.1 5.1 5.4 9.3 3.8 5.2 10.4 15.0 6.4 5.8 8.0 6.3 5.5 6.8 5.4 5.6 5.4 5.6 8.7 6.1 6.7 5.0 13.8 5.6 4.8 6.7 8.8 6.6 6.4 32.4 12.0 7.1 15.0 5.0 3.4 7.7 4.0 5.6 5.6 3.2 5.3 7.8 4.5 4.6 3.9 5.3 4.0 1.9 7.7 2.9 4.1 5.2 6.6 0.0 0.1 3.4 0.6 0.1 0.3 0.2 2.1 3.3 5.7 6.0 9.7 9.0 3.9 4.9 5.8 5.8 4.1 8.3 4.6 1.7 5.1 9.2 6.2 5.7 3.8 7.6 3.4 12.2 2.0 2.8 8.6 4.8 7.6 1.8 8.3 7.6 5.1 12.1 3.5 11.5 7.1 6.2 3.9 4.2 4.5 1.9 4.6 7.2 1.7 6.0 5.3 2.8 5.3 2.0 4.6 3.9 2.8 5.4 3.8 5.0 1.8 8.5 4.2 1.5 8.6 10.7 6.1 12.6 2.6 5.7 1.8 2.6 3.2 1.9 6.2 0.0 0.2 3.4 0.1 0.6 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.2 5.1 9.3 10.4 15.0 6.1 6.7 6.7 8.8 15.0 4.0 0.0 2.6 0.0 0.1 0.7 0.7 1.8 0.0 0.0 0.0 0.0 5.9 0.6 0.0 0.8 20.7 1.5 0.8 0.0 1.7 1.3 2.0 0.2 0.0 3.0 1.3 0.0 0.0 2.5 0.8 31.6 1.4 0.9 1.7 3.6 0.6 0.5 1.8 0.0 2.8 0.8 0.5 6.5 0.9 0.9 1.6 0.9 0.2 3.9 0.7 0.1 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: AB_2681974" "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 26.3 23.4 12.9 21.3 16.0 36.5 28.1 28.3 17.4 17.2 16.4 25.4 19.2 12.3 25.1 22.2 14.6 18.0 21.9 17.4 10.4 11.2 15.9 16.4 20.0 17.2 17.5 16.0 41.3 33.6 19.6 30.0 23.4 14.6 21.0 15.1 20.4 21.8 45.5 19.5 29.3 15.1 25.2 14.5 18.2 17.3 20.8 13.7 12.8 19.3 11.2 22.2 24.6 18.1 6.7 12.4 8.9 5.3 5.6 8.8 2.5 16.0 19.4 5.7 10.6 12.3 13.7 11.0 13.2 13.4 12.7 8.6 18.8 8.1 20.5 6.7 11.7 13.8 11.8 13.4 9.8 22.8 4.9 20.3 18.7 28.3 19.6 12.7 20.5 10.3 11.9 16.3 18.1 40.6 9.8 11.0 9.3 14.9 21.7 10.4 12.3 18.6 20.8 8.8 12.0 15.6 14.4 12.6 13.8 8.0 17.0 16.9 10.3 9.5 44.3 24.0 13.0 11.4 13.1 9.3 30.1 14.0 17.5 23.3 16.1 6.3 25.3 11.8 16.0 9.4 8.9 3.9 3.1 7.6 5.3 8.8 6.4 7.2 6.4 2.3 6.7 8.0 7.7 5.7 5.6 3.3 12.4 4.8 2.5 12.9 16.0 28.3 17.4 10.4 11.2 17.5 16.0 14.6 13.7 11.9 41.5 16.3 21.0 45.9 31.4 13.5 15.3 12.0 26.1 14.0 31.4 6.9 5.0 8.7 12.1 20.4 6.8 0.0 8.3 8.9 25.9 22.8 19.7 12.4 34.2 25.4 17.7 12.3 20.6 6.1 10.9 34.8 28.7 10.8 13.6 17.3 10.7 8.6 11.7 4.1 32.5 6.5 22.7 14.2 10.6 37.9 10.8 30.5 14.0 20.4 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 117.3;Late spermatids: 116.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli NA NA "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 10.4 8.4 9.2 9.7 10.5 19.2 9.0 16.2 10.0 8.3 6.6 10.4 8.0 5.8 9.6 15.8 8.2 7.8 7.0 6.9 7.4 5.5 6.1 7.4 8.1 10.5 8.7 7.8 15.3 6.9 10.7 17.1 8.5 8.7 7.3 7.0 7.4 9.7 9.6 11.1 9.9 7.2 8.1 10.2 7.0 6.6 22.2 10.5 13.4 9.8 5.4 9.4 10.5 9.1 7.4 6.1 7.4 4.8 5.9 9.0 2.5 7.4 5.4 11.5 8.8 3.0 3.7 9.8 5.7 4.1 9.9 11.2 10.2 5.9 6.8 6.2 4.4 7.6 7.1 12.5 6.3 10.9 9.2 6.6 18.3 11.0 6.7 3.4 11.9 9.2 2.0 3.8 10.4 7.5 3.6 4.2 11.9 13.2 13.1 6.2 5.5 15.3 8.2 9.8 4.8 4.7 12.4 17.2 6.2 3.4 8.8 12.6 6.8 9.1 4.5 5.7 11.5 5.2 8.4 5.4 11.2 9.8 6.2 7.4 8.9 7.9 13.9 6.0 8.8 7.6 6.5 4.2 7.4 7.0 4.8 7.3 5.4 5.8 5.9 4.4 7.4 9.0 5.7 3.5 5.9 4.4 6.1 7.3 2.5 9.2 10.5 16.2 10.0 7.4 5.5 8.7 7.8 8.7 10.5 0.0 8.3 11.5 5.5 17.3 16.4 3.3 2.5 10.7 10.3 7.0 25.5 6.1 0.0 4.6 117.3 9.0 5.1 0.0 2.0 5.4 9.3 10.2 4.7 10.2 6.5 14.3 9.9 11.6 8.1 116.2 9.2 13.7 20.3 5.4 8.1 9.9 4.6 6.8 9.2 3.6 21.1 6.5 10.3 40.0 12.8 18.1 6.1 17.9 7.0 5.8 USP38 "HP43.8KD, KIAA1891" ENSG00000170185 "Ubiquitin specific peptidase 38" Q8NB14 4 143184917-143223830 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 45.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036990, HPA047948" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA Nucleoplasm "Centrosome, Cytosol" "HPA036990: AB_2675419, HPA047948: AB_2680220" "unprognostic (5.01e-2)" "unprognostic (2.45e-1)" "unprognostic (2.04e-3)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.49e-2)" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (8.03e-2)" "unprognostic (7.72e-3)" "prognostic favorable (1.20e-4)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.29e-1)" "unprognostic (1.02e-1)" 7.7 7.8 6.6 6.6 6.5 19.1 8.3 7.4 7.8 7.9 12.1 8.6 8.8 8.8 8.3 7.1 8.6 7.1 7.6 12.5 6.6 5.3 9.3 15.2 12.7 11.1 10.3 5.1 6.3 8.8 10.0 6.2 11.4 5.9 6.6 6.6 7.1 7.2 7.0 45.3 8.9 13.2 6.5 10.8 10.6 7.4 7.5 8.2 22.6 8.6 10.2 8.4 7.8 8.8 6.3 8.1 12.5 5.7 12.3 9.9 5.0 4.8 4.5 4.0 6.9 5.3 5.3 3.0 7.7 7.5 7.2 6.1 13.1 7.2 6.0 5.5 6.5 4.6 3.8 9.5 7.7 5.9 14.6 6.1 5.5 5.4 2.8 7.3 11.1 5.5 6.4 7.1 7.3 5.9 5.1 7.1 6.9 11.9 18.9 4.7 7.7 14.5 2.1 3.6 9.8 8.9 9.5 6.0 5.7 4.6 5.6 8.2 7.4 6.0 10.5 6.7 3.1 6.4 4.2 8.4 6.6 5.4 5.7 8.0 21.1 35.7 10.9 6.7 8.5 5.5 12.5 5.4 11.7 7.5 5.7 9.6 6.3 6.6 6.5 8.1 5.7 6.7 5.7 5.4 12.3 5.7 3.5 9.9 5.0 6.6 6.5 7.4 7.7 6.6 5.3 10.3 5.1 5.9 8.2 20.8 13.7 10.5 16.5 47.6 7.5 15.1 7.6 13.4 14.8 0.0 11.8 10.9 1.7 7.5 27.8 12.0 18.4 0.0 6.6 5.8 9.7 16.1 3.5 32.7 9.2 7.9 29.4 17.8 14.5 15.4 6.4 12.2 11.8 1.8 19.9 13.6 8.5 11.5 8.9 14.2 8.2 12.9 15.1 9.5 5.1 51.7 22.3 13.4 14.5 38.1 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277831-49340712 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 100.2;Late spermatids: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favorable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favorable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 22.1 18.4 21.4 22.4 29.3 41.4 23.1 30.3 32.5 20.7 20.1 26.8 16.9 16.1 23.6 20.9 23.5 19.3 17.5 22.8 22.2 18.0 20.2 18.5 25.7 25.5 20.2 17.5 23.6 17.1 23.6 19.7 22.1 24.3 20.9 21.9 23.6 19.1 21.3 25.7 27.6 19.4 25.9 20.4 30.6 17.7 25.0 19.7 36.8 21.2 14.1 42.4 22.1 22.0 17.0 24.1 59.4 27.3 21.5 18.6 22.2 6.4 7.4 10.2 13.6 19.0 20.4 6.9 17.5 15.6 22.7 20.5 7.8 16.2 12.4 7.0 25.5 13.1 8.7 13.6 24.8 21.2 19.1 4.0 27.5 14.7 8.7 27.9 14.5 15.9 20.9 10.9 24.9 20.5 16.5 26.2 14.1 9.6 19.7 21.0 10.9 17.1 24.6 8.7 8.0 12.9 7.1 6.4 10.8 17.8 13.3 8.5 11.4 12.7 9.0 6.5 10.7 6.2 23.3 23.2 15.3 8.3 19.1 10.2 15.8 7.6 18.1 13.7 23.0 17.5 18.0 27.3 30.0 16.9 22.1 18.6 17.0 17.6 16.9 24.1 14.1 17.1 15.0 59.4 21.5 24.4 9.6 18.6 22.2 21.4 29.3 30.3 32.5 22.2 18.0 20.2 17.5 24.3 19.7 38.7 21.4 18.1 15.0 16.7 16.6 15.3 15.3 33.5 25.0 19.2 19.6 18.9 18.3 14.2 100.2 17.9 11.6 0.0 11.9 12.1 12.3 13.1 32.4 12.1 21.7 11.1 10.3 16.0 38.8 90.2 14.4 25.3 15.1 30.7 11.4 12.0 14.6 5.8 18.0 10.5 21.5 12.9 14.7 18.5 13.6 16.2 20.3 24.9 11.9 11.8 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA Vesicles "Focal adhesion sites" "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 12.5 20.5 11.0 8.2 17.7 3.5 16.1 8.2 13.5 12.4 12.1 26.1 22.5 11.6 16.2 28.1 13.9 13.4 13.2 10.8 11.3 8.5 16.9 15.7 13.9 7.6 22.1 10.1 19.6 17.2 22.8 24.3 16.3 16.5 16.1 11.2 16.4 13.9 19.7 13.6 21.7 15.2 17.1 20.1 11.4 16.3 23.3 18.9 9.8 21.2 9.4 12.0 18.0 11.8 1.9 5.0 0.4 2.8 1.4 2.2 1.4 9.5 11.1 10.2 6.9 15.0 14.1 9.0 9.4 7.3 8.8 9.6 7.9 11.4 0.2 2.8 15.1 22.6 17.0 7.8 16.7 12.6 0.0 5.1 7.5 9.2 13.3 13.1 3.1 5.1 13.4 12.1 12.9 18.2 15.4 10.1 4.6 12.1 1.8 12.3 7.7 3.4 4.7 4.5 9.9 9.0 0.0 21.2 4.4 10.4 15.4 5.6 6.1 7.5 7.8 9.7 8.0 8.8 7.1 9.9 12.2 7.6 5.1 11.4 3.4 2.6 0.4 15.9 5.7 10.6 0.0 2.7 0.0 1.3 2.8 0.6 1.3 1.5 1.3 4.0 1.9 1.9 2.2 0.4 1.4 2.3 5.0 2.0 1.4 11.0 17.7 8.2 13.5 11.3 8.5 22.1 10.1 16.5 18.9 29.8 31.5 3.7 9.6 6.5 18.6 8.9 10.2 24.1 23.9 15.7 23.6 17.1 6.6 7.9 6.7 7.1 10.9 0.0 10.6 8.8 7.4 11.3 9.2 20.9 7.0 22.3 14.5 12.3 10.4 7.8 6.4 6.7 3.3 5.4 9.1 13.0 9.7 8.6 7.8 11.6 20.8 12.9 8.2 31.2 14.9 9.3 13.2 4.4 11.2 7.1 USP41 ENSG00000161133 "Ubiquitin specific peptidase 41" Q3LFD5 22 20350578-20390758 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 1.6;RH-30: 4.2;RT4: 1.7;SCLC-21H: 4.9;SK-BR-3: 1.8;U-937: 1.5" NA NA "unprognostic (4.01e-6)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (4.63e-3)" "unprognostic (7.44e-2)" "unprognostic (1.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (9.91e-5)" "unprognostic (3.43e-2)" "unprognostic (3.51e-2)" "unprognostic (2.54e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.63e-1)" 0.7 0.3 0.4 0.0 0.6 1.0 0.6 0.0 1.8 0.3 0.3 1.6 0.2 0.0 0.2 0.2 0.0 0.1 0.4 0.4 0.1 0.9 1.3 0.1 0.2 0.1 0.2 0.0 0.4 0.1 0.4 0.2 0.5 0.0 0.7 0.1 0.3 0.0 0.3 0.3 2.0 0.3 0.4 0.3 0.3 0.1 0.4 1.2 0.3 0.4 0.4 0.5 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.9 0.0 1.6 0.0 0.4 0.0 4.2 0.0 0.0 1.7 4.9 0.2 0.0 1.8 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.8 1.2 1.5 0.3 0.0 0.0 0.3 0.2 0.2 0.4 0.4 0.1 0.5 0.1 0.2 0.0 0.2 0.0 0.4 0.4 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP42 FLJ12697 ENSG00000106346 "Ubiquitin specific peptidase 42" Q9H9J4 7 6104884-6161564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 70.7;Spermatocytes: 67.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064800 Approved Nucleoplasm NA NA Nucleoplasm "HPA064800: AB_2685355" "unprognostic (1.48e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (2.82e-1)" "unprognostic (6.21e-3)" "unprognostic (2.47e-2)" "unprognostic (3.17e-3)" "unprognostic (3.14e-2)" "unprognostic (3.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.66e-1)" 6.7 5.6 5.7 5.7 9.5 19.8 7.2 14.1 10.6 8.5 7.4 10.4 5.5 8.1 14.1 7.0 6.9 8.1 6.5 5.4 5.8 6.0 7.4 7.1 7.3 6.5 6.7 4.9 10.6 11.7 10.5 10.9 8.2 6.2 7.4 6.5 8.9 6.6 6.3 7.4 9.2 9.2 8.7 9.9 7.8 6.7 25.2 8.1 14.3 7.7 6.2 8.3 7.6 6.9 1.9 2.2 3.3 2.4 1.9 4.3 0.8 8.4 6.3 11.4 11.1 6.6 5.0 7.8 4.6 5.9 5.4 5.4 4.4 4.5 10.1 3.0 5.7 8.0 7.9 9.5 5.0 5.9 2.4 7.4 4.6 5.4 4.5 5.6 10.8 5.3 5.9 6.0 5.8 7.5 5.0 6.6 8.5 17.8 6.8 3.6 7.5 6.5 12.1 12.9 4.4 4.8 12.4 8.9 6.9 5.1 4.5 8.8 15.5 5.8 12.2 3.6 10.9 5.6 5.6 5.5 4.9 18.1 6.1 5.4 6.1 5.1 8.8 4.1 6.6 9.5 2.3 1.1 3.3 2.1 2.4 3.0 1.9 2.6 1.3 1.1 1.1 1.7 4.3 1.4 1.9 1.2 2.2 1.8 0.8 5.7 9.5 14.1 10.6 5.8 6.0 6.7 4.9 6.2 8.1 11.9 6.5 11.5 16.3 35.9 18.1 6.9 0.0 10.7 6.8 1.8 21.6 7.3 0.0 9.4 70.7 12.2 12.5 0.0 8.9 6.5 8.5 16.7 9.2 7.8 7.2 20.6 10.3 14.7 7.0 32.5 13.3 11.5 10.1 6.4 14.6 11.3 10.2 7.0 12.0 4.2 17.9 12.9 11.3 67.4 32.6 36.3 22.4 12.1 11.3 13.5 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729691 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell type enhanced" "Detected in many" 11 "Syncytiotrophoblasts: 61.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 12.4;SK-BR-3: 8.6;T-47d: 10.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762" Uncertain NA NA "HPA023389: AB_1858691, HPA027762: AB_10603001" "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.2 0.2 4.2 1.2 3.4 0.9 3.0 0.7 6.0 4.9 10.0 0.6 15.7 6.2 2.9 1.7 6.7 6.3 5.1 0.2 4.1 3.8 3.7 8.7 3.4 0.2 1.7 3.1 1.0 7.7 1.7 3.7 61.6 0.7 10.8 5.0 0.3 11.3 12.4 0.2 2.4 12.5 0.3 1.0 0.2 2.6 2.9 0.2 0.4 1.7 4.2 2.7 1.3 2.1 0.0 0.5 0.0 0.0 1.1 0.1 0.1 5.7 1.5 0.0 0.6 0.0 0.0 12.4 0.1 0.2 0.7 1.7 2.8 4.7 0.0 1.9 0.2 2.7 7.0 0.6 5.5 0.7 3.6 1.9 0.3 3.0 1.0 0.1 0.5 0.0 0.0 7.2 0.3 3.0 0.3 0.0 0.8 0.0 0.0 0.0 2.7 0.9 4.7 0.7 4.9 0.3 3.7 0.0 0.8 4.4 3.1 0.8 0.0 2.5 8.6 1.0 4.1 10.4 1.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 4.2 3.4 0.7 6.0 4.1 3.8 1.7 3.1 0.7 0.2 3.0 1.9 0.0 7.2 4.1 0.0 0.5 7.6 21.4 7.9 10.4 5.9 16.6 1.7 3.9 1.1 0.0 9.0 0.0 4.0 19.6 0.6 9.5 0.0 12.4 2.4 0.0 2.4 0.0 1.6 0.8 0.0 0.0 5.0 0.0 7.8 8.1 8.5 2.9 0.0 1.3 1.3 0.0 0.3 1.1 0.2 2.9 61.2 0.0 9.0 10.0 USP44 FLJ14528 ENSG00000136014 "Ubiquitin specific peptidase 44" Q9H0E7 12 95516560-95551490 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.8" "Cell type enriched" "Detected in many" 4 "Early spermatids: 343.6" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Region enriched" "Detected in many" 5 "cerebellum: 10.9" "Cell type enhanced" "Detected in many" "naive CD4 T-cell: 8.6" "Group enriched" "Detected in many" 39 "B-cells: 5.6;T-cells: 8.6" "Cell line enhanced" "Detected in some" "HEL: 10.0;JURKAT: 22.6;NTERA-2: 54.2" "Low region specificity" "Detected in some" HPA026543 Approved "Nucleoli fibrillar center,Microtubules" NA NA "Nucleoli fibrillar center, Microtubules" "HPA026543: AB_1858692" "unprognostic (2.12e-2)" "unprognostic (1.14e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (1.83e-4)" "unprognostic (7.18e-4)" "unprognostic (5.55e-2)" "unprognostic (1.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.73e-2)" "unprognostic (6.88e-2)" "unprognostic (2.97e-2)" "unprognostic (8.12e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.41e-2)" "unprognostic (7.07e-2)" 1.3 1.0 0.7 1.2 1.3 0.5 1.4 10.9 2.1 1.7 1.7 1.7 1.4 0.5 3.0 1.0 0.9 1.6 1.1 1.0 0.7 0.6 1.9 0.2 4.7 1.9 1.3 1.2 1.6 3.6 4.8 4.0 0.3 1.8 1.7 0.6 2.3 1.8 2.6 0.4 0.6 1.3 1.2 0.6 1.9 1.0 26.8 1.2 0.8 1.7 0.0 1.6 1.1 2.3 5.6 0.1 0.1 0.0 0.1 8.6 1.3 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.4 1.3 0.5 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.2 10.0 0.0 0.0 2.3 4.0 0.2 0.0 0.0 0.3 0.0 0.2 0.2 22.6 1.5 0.0 0.0 0.0 5.1 0.0 54.2 0.0 0.0 0.0 0.0 0.0 0.9 0.3 3.5 2.3 0.0 0.0 0.0 5.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 3.4 5.6 2.3 2.0 0.0 4.4 8.6 5.5 0.1 0.1 0.0 0.1 0.3 1.3 0.7 1.3 10.9 2.1 0.7 0.6 1.3 1.2 1.8 1.2 11.9 19.9 0.0 2.9 0.9 6.2 1.2 0.0 0.0 6.8 7.0 5.9 2.1 0.0 3.9 343.6 2.3 0.0 0.0 2.7 0.3 1.0 2.7 0.0 0.0 0.1 0.0 0.0 1.3 0.3 78.5 5.2 0.4 3.3 1.0 0.0 3.4 1.3 0.0 3.2 1.1 8.6 6.5 3.1 10.0 5.2 0.6 0.9 1.7 0.0 1.6 USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432379-99521728 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604" Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA029602: AB_10600418, HPA029604: AB_10602283" "unprognostic (7.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (2.95e-3)" "unprognostic (1.10e-1)" "unprognostic (3.43e-3)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.43e-1)" "unprognostic (6.91e-2)" 9.8 9.1 8.5 10.2 12.2 7.2 9.0 28.4 11.6 9.0 9.7 8.6 8.9 13.7 15.7 9.6 10.0 8.1 11.9 11.5 7.7 8.5 12.2 9.0 7.1 12.7 9.8 8.0 10.7 9.6 10.2 21.7 9.6 15.0 9.9 13.1 7.9 9.8 8.4 14.6 11.8 12.4 10.8 10.6 9.9 8.9 5.7 9.4 7.1 10.7 10.4 9.5 8.8 15.0 8.6 5.1 3.7 2.5 2.6 6.2 1.4 4.2 3.0 6.0 8.5 11.2 10.6 6.4 7.4 8.3 7.7 11.1 6.3 4.8 11.3 5.5 7.4 9.1 5.8 9.2 7.3 10.7 8.9 8.8 11.0 6.0 4.9 8.6 10.2 6.3 11.3 5.9 6.9 11.9 8.2 11.4 10.3 26.5 11.3 7.3 3.9 3.2 9.8 9.7 6.6 6.5 4.8 4.5 6.3 10.8 5.0 8.5 7.0 5.3 6.9 5.4 7.9 3.7 5.0 11.5 4.2 5.4 6.2 11.2 4.8 4.4 20.7 7.3 9.7 7.5 3.7 2.0 0.6 4.9 1.3 6.2 7.4 4.2 5.6 3.5 8.6 3.0 2.9 0.5 2.6 2.5 5.1 3.5 1.4 8.5 12.2 28.4 11.6 7.7 8.5 9.8 8.0 15.0 9.4 3.0 4.3 4.4 6.8 2.1 7.9 7.1 7.6 12.0 3.4 3.5 17.7 5.3 5.0 3.9 10.8 5.3 5.8 0.0 2.3 5.9 3.8 5.6 2.3 3.8 3.5 9.5 2.4 8.0 4.1 5.9 12.0 3.9 3.3 13.6 2.3 5.6 4.3 2.9 8.1 13.4 7.6 0.0 6.2 1.8 5.5 2.5 6.2 5.1 6.0 6.5 USP46 FLJ12552 ENSG00000109189 "Ubiquitin specific peptidase 46" P62068 4 52590972-52659335 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Behavior, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Bipolar cells: 123.5;Early spermatids: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007288, CAB076369, CAB076370" Uncertain Approved "Nucleoli,Nucleoli rim" NA NA "Nucleoli, Nucleoli rim" "CAB076369: AB_2665642, CAB076370: AB_2665643, HPA007288: AB_1080531" "unprognostic (1.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (1.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-3)" "unprognostic (1.59e-1)" "unprognostic (2.45e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (3.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" 4.7 9.5 26.0 3.5 20.9 2.8 7.0 23.7 29.4 8.9 4.2 12.8 5.2 4.8 7.2 6.2 12.4 7.8 5.8 28.9 21.9 19.0 10.8 3.1 4.4 3.7 19.1 13.9 12.3 5.6 12.2 5.3 10.6 12.7 7.7 4.6 5.3 8.0 7.8 13.7 8.0 4.5 5.5 18.9 3.5 6.3 12.2 15.0 1.0 10.0 4.3 5.8 7.3 5.7 1.4 4.4 2.0 1.4 1.2 3.9 1.0 5.4 3.8 12.5 9.2 13.6 17.1 13.8 8.9 7.2 6.6 5.6 7.7 4.2 3.6 10.5 8.8 9.3 3.2 21.7 10.3 12.1 3.1 7.6 5.6 3.7 8.6 13.6 7.3 6.5 14.5 9.7 6.8 6.4 12.9 9.8 5.1 5.5 5.1 13.9 4.9 3.1 3.9 9.2 6.0 4.7 8.0 9.1 0.7 14.2 10.0 7.5 9.0 4.3 14.9 8.5 12.5 5.4 5.5 9.0 6.5 14.2 7.6 13.3 5.2 2.4 2.9 10.0 4.5 8.0 2.0 1.4 0.3 2.3 1.2 1.7 1.4 3.9 2.0 2.8 1.2 0.9 0.8 0.3 1.2 0.9 4.4 1.2 1.0 26.0 20.9 23.7 24.3 21.9 19.0 19.1 13.9 12.7 15.0 6.0 4.5 1.9 9.8 4.7 123.5 42.3 12.7 24.1 11.4 14.0 3.9 10.5 18.3 10.3 151.7 8.4 3.8 0.0 10.5 10.9 10.3 17.3 0.0 5.7 5.0 33.4 4.1 7.4 7.6 24.3 26.7 4.4 8.5 14.4 5.6 21.3 9.7 7.6 33.9 12.6 7.9 6.5 8.3 3.0 11.5 7.2 6.4 4.4 6.0 15.9 USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11959323 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported Approved "Vesicles,Intermediate filaments" NA NA "Intermediate filaments" Vesicles "HPA029286: AB_10599852, HPA029289: AB_10601675" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.27e-2)" "unprognostic (7.39e-2)" "unprognostic (1.54e-2)" "unprognostic (7.05e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (9.96e-3)" "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" 16.6 17.0 17.9 18.5 20.9 20.3 16.9 25.7 19.0 16.4 18.1 16.2 21.3 11.6 18.0 15.0 18.7 13.7 13.5 25.5 18.1 13.4 14.6 25.1 16.6 13.4 21.9 12.9 16.9 19.6 38.8 31.8 23.7 19.3 18.0 14.2 10.2 15.1 19.2 58.1 18.4 15.1 21.3 19.5 13.3 18.1 16.8 23.9 27.9 16.8 12.4 15.2 21.3 19.4 9.7 10.1 14.0 13.2 22.8 19.3 9.7 21.4 13.1 23.5 11.1 17.0 18.8 10.8 24.7 18.7 16.3 18.5 12.9 19.1 24.3 11.8 22.9 19.4 14.7 18.1 12.4 25.2 23.6 15.3 14.6 24.2 9.0 15.1 18.9 20.5 17.4 17.1 10.7 23.8 18.6 18.1 17.2 29.1 21.0 19.9 8.5 17.0 8.4 6.3 21.3 10.6 17.6 24.8 7.5 17.6 24.9 8.2 16.7 22.1 15.4 13.7 15.1 12.3 13.9 20.0 23.1 14.1 19.6 15.0 6.6 15.2 23.0 15.9 11.7 16.6 13.3 7.7 14.0 15.2 9.5 19.3 9.7 13.8 14.7 10.1 8.6 17.9 15.3 3.6 22.8 13.2 6.1 9.9 9.7 17.9 20.9 25.7 19.0 18.1 13.4 21.9 12.9 19.3 23.9 65.5 50.8 26.5 58.2 63.1 66.5 188.1 30.6 62.9 67.1 22.7 45.2 55.8 21.6 33.6 26.3 35.8 25.1 23.3 33.7 29.2 48.3 58.2 51.0 50.0 24.2 60.4 56.9 30.1 18.5 22.9 40.9 32.0 23.6 27.9 30.5 80.7 36.7 31.6 47.0 17.9 50.6 51.8 47.2 72.0 59.0 76.9 105.2 47.3 32.2 47.7 USP48 "FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31" ENSG00000090686 "Ubiquitin specific peptidase 48" Q86UV5 1 21678298-21783606 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030045, HPA030046" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA Nucleoplasm "Mitochondria, Cytosol" "HPA030045: AB_10670833, HPA030046: AB_10603325" "unprognostic (1.35e-1)" "unprognostic (3.72e-1)" "unprognostic (5.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (6.09e-8)" "unprognostic (1.04e-2)" "unprognostic (3.01e-3)" "unprognostic (9.30e-2)" "unprognostic (7.54e-2)" "unprognostic (4.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.80e-2)" 20.1 38.8 18.6 28.9 30.9 30.9 22.1 48.2 27.5 19.9 18.4 25.6 15.4 17.6 21.3 17.6 19.0 17.4 20.5 17.8 16.9 15.8 15.5 18.3 18.3 26.2 26.6 22.5 27.0 19.8 24.6 35.4 23.1 26.8 21.6 22.0 22.1 24.5 16.3 17.0 23.9 22.2 22.2 19.7 29.1 26.2 15.8 23.6 25.8 23.9 14.0 29.0 19.8 21.0 13.7 10.5 33.7 9.6 5.6 11.2 5.6 14.9 7.1 16.8 12.1 14.6 18.0 16.6 18.8 12.8 12.7 16.8 6.5 15.3 16.8 12.7 17.0 9.9 13.8 20.6 15.2 19.3 16.3 14.1 35.9 26.5 11.8 13.0 18.0 19.2 14.6 13.1 12.8 14.3 17.4 37.2 12.8 28.2 47.5 15.5 7.4 14.9 23.4 10.5 15.3 12.8 21.0 16.9 19.6 14.5 12.6 20.5 12.8 17.7 16.3 42.5 23.5 8.3 21.8 26.4 13.7 11.2 16.7 10.9 38.2 27.1 16.7 13.2 22.3 20.0 33.7 9.6 16.7 6.4 4.6 7.6 13.7 9.5 9.5 10.5 12.8 11.2 7.0 8.9 5.6 5.0 7.7 10.1 5.6 18.6 30.9 48.2 27.5 16.9 15.8 26.6 22.5 26.8 23.6 50.6 38.5 34.3 22.6 19.7 74.8 58.2 22.9 32.1 20.5 19.2 58.9 51.8 21.6 25.0 51.8 24.5 18.7 70.0 17.5 50.1 30.9 20.6 47.5 21.2 26.0 47.7 20.8 28.3 22.2 33.0 32.2 24.7 55.6 47.7 26.9 29.1 20.0 17.5 48.4 16.5 69.2 32.3 25.0 42.9 48.2 22.5 27.2 35.5 30.2 17.1 USP49 MGC20741 ENSG00000164663 "Ubiquitin specific peptidase 49" Q70CQ1 6 41789896-41895361 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Bipolar cells: 21.6;Cone photoreceptor cells: 41.2;Erythroid cells: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Cell line enhanced" "Detected in many" "REH: 23.7;U-698: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030254, HPA030255" Uncertain NA NA "HPA030254: AB_10600198, HPA030255: AB_10601218" "unprognostic (1.71e-1)" "unprognostic (4.86e-3)" "unprognostic (1.93e-1)" "unprognostic (2.57e-4)" "unprognostic (4.46e-2)" "unprognostic (2.84e-4)" "unprognostic (7.17e-3)" "unprognostic (5.06e-2)" "unprognostic (1.19e-2)" "unprognostic (3.22e-1)" "unprognostic (5.59e-3)" "unprognostic (8.28e-2)" "unprognostic (1.26e-5)" "unprognostic (5.39e-2)" "unprognostic (4.58e-2)" "unprognostic (4.37e-3)" "unprognostic (3.24e-3)" 2.4 2.4 7.6 3.5 6.0 7.3 2.7 12.7 9.3 2.3 1.9 2.0 4.3 2.2 4.0 2.3 1.8 2.2 2.1 3.5 7.6 4.2 1.6 1.7 2.4 3.7 3.0 5.8 4.0 3.2 2.6 4.8 1.8 4.2 2.4 2.1 3.7 2.7 2.4 3.8 4.1 2.2 3.2 3.2 3.5 2.2 7.4 3.2 7.3 7.7 0.6 3.4 2.8 2.0 1.2 0.7 8.5 1.8 0.8 0.9 0.4 3.0 0.9 12.5 6.1 1.5 1.7 5.1 1.2 1.1 1.8 2.3 3.9 0.7 12.5 1.3 1.5 2.6 1.3 7.7 1.2 2.8 3.1 5.7 4.5 4.7 1.3 1.1 3.5 2.7 1.7 0.9 2.6 1.7 1.7 1.1 13.0 9.3 3.5 1.4 1.8 13.3 5.3 3.4 3.2 1.2 23.7 6.0 2.7 0.7 2.1 8.4 3.4 1.6 0.6 0.7 3.1 1.9 3.2 3.2 4.3 4.3 1.4 1.6 6.5 5.6 33.7 0.5 3.6 0.8 8.5 1.3 1.4 0.8 1.5 0.4 1.2 0.4 0.8 0.5 0.9 0.9 0.7 2.4 0.8 1.8 0.7 0.4 0.4 7.6 6.0 12.7 9.3 7.6 4.2 3.0 5.8 4.2 3.2 0.0 11.9 1.5 2.8 4.4 21.6 3.4 5.1 1.4 6.8 5.2 41.2 2.3 1.7 1.5 6.4 2.4 1.6 23.3 1.7 1.3 3.6 3.3 1.1 1.5 1.8 14.3 0.0 1.3 4.1 6.3 3.4 3.6 3.3 1.0 1.4 3.1 1.8 1.7 5.6 1.0 11.9 6.5 2.5 8.9 15.8 5.5 4.8 2.2 1.7 3.9 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852128-6866632 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol NA NA 820000 "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 18.6 28.7 23.1 17.8 32.6 13.6 12.9 24.6 50.9 15.9 21.5 26.8 13.8 17.6 22.3 12.8 27.7 19.1 14.7 22.4 23.9 28.6 14.9 24.8 14.4 18.6 23.6 33.2 14.4 13.2 29.7 19.6 21.7 36.8 19.5 16.1 11.6 14.1 22.7 41.2 33.5 18.1 25.3 23.6 14.1 15.9 30.9 18.7 22.8 19.2 20.4 19.9 21.3 16.0 10.8 18.6 5.3 16.6 10.8 17.1 16.6 25.6 40.1 27.0 30.5 18.4 17.0 34.5 27.9 21.4 33.4 24.4 37.9 25.5 31.0 14.7 29.0 26.5 22.7 29.6 27.7 21.4 58.2 25.1 28.4 32.3 20.6 14.3 25.6 30.0 17.1 16.1 28.9 20.0 22.4 28.5 12.5 24.4 12.5 27.5 28.1 38.5 12.8 52.6 26.2 17.0 30.3 35.2 21.5 19.1 25.0 14.9 30.1 19.0 29.0 12.1 35.1 11.6 21.1 27.6 28.3 34.3 21.5 34.7 15.0 34.6 47.3 31.5 16.4 27.5 2.3 12.3 5.3 17.1 16.6 16.1 10.8 15.2 14.4 18.6 10.0 14.6 14.8 0.9 10.8 14.7 13.6 12.9 16.6 23.1 32.6 24.6 50.9 23.9 28.6 23.6 33.2 36.8 18.7 8.9 12.5 13.0 9.5 10.3 18.1 8.1 17.8 4.0 5.7 21.0 56.9 38.0 10.0 25.9 8.7 7.9 17.7 0.0 17.8 24.3 16.4 7.4 14.9 19.7 24.7 38.1 16.0 9.2 12.1 15.5 21.3 9.6 15.1 47.7 14.7 13.8 16.9 17.8 31.8 14.7 14.5 32.3 9.7 24.5 23.8 13.6 44.2 14.1 22.7 5.6 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 34.1" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 24.4;Ciliated cells: 17.4;Muller glia cells: 29.9" "Low cancer specificity" "Detected in many" "Cell type enhanced" "Detected in some" "eosinophil: 2.4;naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 10.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favorable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favorable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 0.6 2.7 2.0 0.3 2.9 0.1 0.9 2.3 1.8 1.4 0.6 0.0 1.8 34.1 0.2 3.4 0.3 1.0 1.8 3.7 2.2 0.5 0.7 0.4 1.6 4.1 0.8 3.6 1.8 1.3 1.3 0.3 0.3 1.5 0.0 0.5 0.5 1.1 1.4 0.9 0.3 1.3 3.2 0.5 0.7 0.5 0.9 0.0 2.4 0.0 0.6 2.4 0.1 0.0 0.8 5.4 1.6 2.7 1.4 0.0 0.9 0.4 1.0 1.3 1.7 0.7 0.0 6.4 1.2 1.1 0.3 1.4 0.6 1.6 1.7 0.1 1.4 0.3 0.0 1.1 3.3 0.3 5.5 0.1 0.6 0.0 0.4 0.3 4.1 4.1 4.1 0.9 3.5 3.2 1.7 6.7 0.0 0.3 4.6 1.0 2.1 1.3 0.2 0.0 1.1 1.5 0.2 5.0 10.2 1.3 1.7 0.2 2.1 2.9 0.5 0.1 6.5 2.6 1.3 1.4 1.8 1.4 0.0 0.0 2.4 0.3 0.0 0.0 0.6 0.6 0.0 0.0 0.9 2.4 0.2 0.0 0.6 0.0 0.0 0.0 0.1 3.0 5.6 0.0 1.7 0.8 24.4 5.0 0.0 17.4 3.4 3.5 5.9 3.4 8.3 1.0 0.3 5.8 0.0 0.0 0.0 2.1 4.3 1.1 1.1 0.8 6.1 6.4 3.5 4.9 3.9 0.8 3.7 2.5 5.0 0.0 0.3 29.9 0.3 0.0 7.8 12.2 15.2 0.0 3.9 3.6 6.7 0.4 2.3 1.7 0.2 0.4 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116438-5175034 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "skeletal muscle: 18.2;testis: 29.0" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 19.3;Erythroid cells: 23.3;Spermatocytes: 19.2" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046969 Uncertain Vesicles NA NA Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.3 0.3 0.3 0.3 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.3 1.2 0.0 0.6 0.6 0.3 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.3 0.3 2.6 0.3 0.0 0.4 0.4 0.3 0.4 0.1 0.3 0.3 0.3 18.2 0.6 0.7 0.9 0.3 0.3 0.0 29.0 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.9 1.2 1.9 1.0 0.2 0.4 0.1 2.2 0.9 2.2 1.6 0.4 0.2 2.3 1.9 0.1 0.6 0.4 0.8 1.0 2.2 1.6 1.2 1.9 1.0 0.7 0.8 0.5 1.5 1.3 1.7 1.3 0.9 1.2 0.5 2.8 1.1 0.5 0.1 0.2 2.5 0.3 1.8 0.5 0.3 0.5 2.5 1.8 0.7 1.5 0.7 0.1 1.4 1.9 0.2 0.5 0.7 0.9 2.1 1.0 0.1 3.3 3.7 2.1 2.2 1.2 0.9 3.2 2.0 1.4 2.0 1.6 1.5 0.0 0.1 2.6 0.1 0.4 0.9 0.4 0.3 0.2 0.6 0.3 0.3 0.3 0.9 0.3 0.4 1.9 0.2 1.0 1.2 0.1 0.1 0.3 0.6 0.5 0.3 0.3 0.1 0.3 0.3 0.3 0.3 6.0 9.6 0.5 0.9 9.6 7.9 1.6 7.6 5.3 5.7 3.5 11.8 0.5 3.3 0.0 19.3 2.9 0.0 23.3 0.0 0.8 1.5 2.4 0.0 2.6 2.3 1.6 0.0 4.9 4.9 9.4 1.7 5.7 3.3 0.0 0.0 4.7 0.1 0.0 2.5 2.8 9.8 6.5 0.6 19.2 5.5 9.2 0.6 0.7 0.0 0.9 USP7 HAUSP ENSG00000187555 "Ubiquitin specific peptidase 7" Q93009 16 8892094-8964514 "Enzymes, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" "Developmental protein, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Early spermatids: 217.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008108, HPA015641, CAB079904" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "CAB008108: AB_2233500, CAB079904: AB_2552261, HPA015641: AB_1858700" "unprognostic (6.73e-2)" "unprognostic (1.59e-1)" "unprognostic (3.36e-3)" "unprognostic (1.94e-2)" "unprognostic (9.64e-2)" "unprognostic (8.09e-2)" "unprognostic (4.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.81e-1)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (9.93e-2)" "prognostic favorable (8.56e-5)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (7.31e-2)" "unprognostic (2.69e-1)" 17.8 16.8 23.9 25.8 22.9 37.6 21.3 28.7 24.5 21.2 26.3 16.2 18.4 17.7 23.5 16.4 24.4 20.3 18.7 23.7 22.8 20.8 16.5 21.3 21.0 30.5 19.6 22.6 22.5 24.0 44.4 19.7 19.3 16.2 18.5 27.4 16.0 18.4 20.3 42.2 25.2 21.5 22.7 15.3 22.9 22.6 43.3 16.5 68.8 19.5 22.3 35.1 23.9 31.7 7.5 9.8 5.5 7.8 3.9 8.7 1.8 12.4 23.3 20.6 15.4 11.7 15.0 14.2 17.2 14.8 16.1 13.7 20.8 15.3 30.1 11.0 19.9 9.2 15.6 31.5 20.6 27.0 19.7 12.5 25.0 15.7 42.9 16.9 27.5 16.2 12.9 13.1 17.5 20.7 12.4 22.8 45.5 24.1 33.4 16.4 23.8 40.3 5.3 14.4 15.8 13.5 35.9 23.1 27.5 11.3 24.5 19.5 12.0 19.3 18.2 9.5 22.0 18.1 12.3 19.5 17.5 17.9 26.8 12.9 16.2 39.6 46.0 16.3 16.0 14.0 5.5 3.3 3.8 7.1 3.2 8.7 5.9 6.6 8.2 3.3 7.5 8.0 6.8 5.2 3.9 7.8 9.8 7.0 1.8 23.9 22.9 28.7 24.5 22.8 20.8 19.6 22.6 16.2 16.5 32.8 46.2 23.4 19.2 41.3 47.4 61.8 20.4 46.8 46.6 27.9 23.6 18.4 5.0 21.1 217.0 25.9 29.6 46.7 28.3 12.6 24.0 27.0 25.5 34.2 17.5 41.3 40.6 25.2 28.0 84.4 23.6 28.5 18.6 16.2 46.7 25.0 27.8 28.8 32.5 11.8 41.6 6.5 29.2 29.9 31.9 43.7 17.6 26.6 47.0 32.7 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514419 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" NA NA "Golgi apparatus" Cytosol "HPA050215: AB_2681054" "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 19.4 21.9 21.0 20.6 20.6 21.6 18.1 27.3 21.6 21.4 23.9 13.8 19.5 20.2 22.1 17.4 22.3 17.4 15.5 17.4 19.7 18.2 28.2 26.4 17.0 25.4 21.8 15.2 21.9 16.7 42.6 43.2 29.1 29.7 16.7 18.9 10.7 19.9 17.9 24.3 17.8 32.1 19.2 29.3 30.3 17.7 27.5 26.1 28.9 24.1 12.7 20.9 22.3 18.4 16.7 10.6 38.1 15.1 9.5 11.9 6.9 11.2 16.2 9.1 16.0 16.6 18.7 12.6 16.2 19.2 15.8 18.7 10.8 7.5 11.9 12.5 18.5 17.8 21.8 12.4 12.1 18.7 10.4 8.2 21.9 15.1 11.0 17.1 14.7 14.9 14.4 14.6 13.9 23.6 14.7 15.3 8.5 12.5 14.5 14.8 23.1 9.4 5.8 10.4 12.9 7.5 8.5 16.9 17.8 15.0 26.5 11.6 10.6 17.0 25.5 21.2 20.1 14.0 18.0 17.3 16.4 9.2 50.5 21.3 11.3 23.4 13.1 13.1 29.7 15.8 38.1 13.3 22.4 11.1 12.4 10.7 16.5 11.4 11.1 10.6 16.7 11.9 10.7 22.7 9.5 15.1 9.9 8.5 6.9 21.0 20.6 27.3 21.6 19.7 18.2 21.8 15.2 29.7 26.1 89.3 104.5 61.4 35.4 25.6 51.6 61.8 48.4 147.2 88.7 45.4 64.8 49.9 21.6 44.4 53.0 44.9 70.6 23.3 44.6 38.3 35.3 38.8 83.3 45.5 40.2 31.8 51.2 53.4 59.1 12.4 49.8 49.2 38.8 52.3 54.2 53.3 45.7 54.3 58.0 40.7 75.6 45.3 42.6 86.1 47.1 36.3 88.0 47.9 55.0 52.6 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9, X-linked" Q93008 X 41085635-41236579 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles NA NA Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 18.0 21.8 17.7 14.0 15.9 15.5 16.8 16.6 16.7 18.4 20.6 11.4 25.4 13.2 19.6 19.0 17.3 17.0 17.1 20.9 14.2 14.2 18.5 34.2 16.7 23.1 15.2 15.4 15.7 16.5 45.8 17.0 41.1 12.9 13.4 14.4 13.9 14.2 25.2 42.8 14.8 22.0 17.3 14.0 16.7 16.9 16.9 14.0 21.1 20.3 17.6 16.5 20.3 19.9 6.4 5.5 13.0 5.0 4.9 7.8 3.1 18.2 21.6 19.2 19.6 16.1 16.9 4.4 10.5 14.1 12.0 13.9 9.9 8.5 12.3 5.9 23.9 35.9 12.4 32.9 19.1 20.1 15.4 23.6 14.2 20.9 8.9 13.6 12.3 10.4 14.6 8.6 28.7 27.2 17.2 18.5 8.3 17.2 10.0 18.5 13.3 8.8 4.9 20.3 6.5 11.9 9.7 26.2 7.9 11.4 15.1 10.9 10.2 44.2 12.2 12.0 36.0 11.8 6.9 19.7 18.3 14.2 17.3 11.3 9.2 10.7 15.7 13.1 5.5 9.1 3.3 4.7 6.0 5.6 4.2 7.8 6.4 6.6 6.2 5.5 4.7 6.7 6.0 13.0 4.9 5.0 4.2 5.6 3.1 17.7 15.9 16.6 16.7 14.2 14.2 15.2 15.4 12.9 14.0 38.7 32.0 23.8 26.8 42.8 35.0 73.6 43.3 30.8 36.4 26.2 35.3 31.0 6.6 26.8 13.0 39.8 39.2 70.0 22.8 21.8 35.1 30.2 24.4 55.5 29.3 35.0 25.8 52.8 43.4 13.1 30.8 38.0 32.1 33.3 42.5 32.0 27.0 35.7 46.3 20.3 29.3 32.3 39.6 31.4 69.2 48.3 39.0 26.1 36.7 34.3 USP9Y DFFRY ENSG00000114374 "Ubiquitin specific peptidase 9, Y-linked" O00507 Y 12701231-12860839 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 60.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.4;dendritic cells: 2.0;T-cells: 2.7" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 16.2;RT4: 8.7" "Not detected" "Not detected" HPA057687 Uncertain Vesicles NA NA Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 1.2 2.2 1.4 0.9 3.1 1.7 1.1 9.6 4.0 0.0 1.6 1.4 0.0 8.6 4.4 0.0 3.8 2.4 1.8 3.4 2.9 2.2 2.2 1.4 2.1 0.0 2.7 0.0 4.8 1.7 9.3 4.8 2.3 7.6 2.8 2.0 1.8 0.0 1.5 2.2 1.5 2.9 2.8 4.5 3.2 0.0 2.4 2.0 0.1 0.2 0.5 2.7 0.2 0.0 2.3 0.0 0.0 0.0 0.0 2.5 7.2 7.2 3.6 3.9 0.0 0.0 4.1 0.0 6.0 0.0 0.0 0.0 0.0 3.3 2.3 0.0 2.6 0.0 7.1 4.0 0.0 0.0 6.0 5.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 6.5 0.0 4.0 0.0 1.5 0.0 0.0 0.0 2.0 0.9 16.2 8.7 2.8 0.0 0.0 0.0 2.1 5.4 0.0 0.0 5.5 4.4 0.0 0.0 3.2 0.0 3.8 7.1 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.2 2.7 1.2 2.2 1.5 0.3 2.4 2.2 1.3 0.1 0.5 0.0 2.0 1.6 0.2 23.8 19.7 0.8 7.4 10.4 22.1 24.6 2.5 21.4 15.9 19.2 60.9 4.3 1.7 4.1 0.4 5.8 0.0 0.0 0.0 1.1 9.3 11.2 2.3 0.2 2.5 25.4 0.0 5.5 6.9 0.0 11.5 7.3 3.3 2.8 0.3 8.1 3.7 0.0 14.5 5.4 24.9 0.0 7.6 3.2 1.7 10.2 2.9 10.0 0.0 9.9 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.3" "Cell type enhanced" "Detected in all" 8 "Hepatocytes: 682.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 98.9" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 21.3 23.0 9.3 11.5 11.0 12.9 28.1 9.4 14.5 24.3 19.3 17.1 16.5 12.6 24.0 27.4 18.5 17.8 22.6 20.1 9.8 10.2 29.9 173.3 16.4 17.5 13.7 9.1 25.5 55.5 14.0 25.0 22.5 13.3 22.3 12.6 20.8 34.8 21.4 11.4 15.9 26.8 27.7 12.5 15.4 17.5 18.2 10.6 15.8 25.6 13.8 14.6 28.4 18.7 32.3 49.9 59.6 40.6 24.7 43.7 33.6 10.5 27.1 8.9 25.5 98.9 58.9 9.9 39.1 34.0 19.3 32.8 11.2 12.1 8.3 21.2 48.9 13.6 9.8 12.3 15.3 22.0 11.7 29.9 7.5 37.5 53.9 15.6 14.6 11.3 34.0 8.2 26.6 22.9 52.3 20.8 11.8 9.8 19.8 37.6 38.2 10.7 30.0 16.1 14.6 26.1 19.4 23.7 41.2 19.0 9.2 18.2 22.1 17.1 12.5 19.0 15.0 20.6 17.8 18.1 25.9 9.3 23.7 14.7 12.0 11.1 7.3 67.4 25.3 13.3 21.5 40.6 59.6 40.3 28.1 39.7 29.9 40.5 40.7 39.6 32.3 36.4 35.4 34.2 24.7 28.3 49.9 43.7 33.6 9.3 11.0 9.4 14.5 9.8 10.2 13.7 9.1 13.3 10.6 53.6 38.2 37.9 58.4 75.2 11.2 20.0 119.8 32.1 40.9 102.9 7.9 64.0 53.0 183.3 4.8 87.9 36.0 46.7 112.2 211.1 138.5 58.9 55.3 682.4 166.1 9.5 64.4 119.7 79.0 8.3 146.4 85.1 109.6 129.8 41.2 64.7 107.2 24.6 161.9 160.1 16.9 58.2 95.7 23.7 24.7 97.9 33.1 47.3 51.3 46.5 VNN3 HSA238982 ENSG00000093134 "Vanin 3" Q9NY84 6 132722787-132734765 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "blood: 39.5;bone marrow: 29.8;liver: 29.4" "Group enriched" "Detected in some" 5 "Ciliated cells: 69.6;Club cells: 19.4" "Cancer enhanced" "Detected in some" "liver cancer: 3.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "neutrophil: 39.5" "Lineage enriched" "Detected in single" 40 "granulocytes: 39.5" "Cell line enhanced" "Detected in some" "Daudi: 2.5;EFO-21: 3.7;GAMG: 1.6;hTCEpi: 2.3" "Secreted to blood" NA NA 150000000 "unprognostic (3.20e-2)" "unprognostic (2.70e-1)" "unprognostic (7.92e-3)" "unprognostic (1.71e-2)" "unprognostic (3.05e-3)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (5.84e-8)" "unprognostic (1.25e-2)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" 1.1 0.1 0.4 3.3 0.4 29.8 0.2 0.2 0.6 2.4 1.2 0.2 0.2 0.0 0.2 0.8 0.9 2.4 1.3 1.0 0.4 0.0 0.3 29.4 6.1 1.2 0.4 0.2 1.2 0.2 0.0 0.2 5.8 0.3 0.5 0.0 0.4 1.1 0.2 0.2 0.1 0.2 0.2 0.2 7.6 0.4 0.3 0.2 0.2 0.3 2.4 0.7 0.6 0.3 0.0 0.0 39.5 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 2.5 3.7 0.0 1.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 6.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.6 0.4 0.0 0.4 0.2 0.3 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 69.6 19.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 9.7 0.1 0.0 0.0 0.6 9.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 VRK1 ENSG00000100749 "Vaccinia related kinase 1" Q99986 14 96797304-96931722 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 93.5;Spermatocytes: 141.1;Spermatogonia: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 6.0 4.4 7.1 9.8 17.1 39.0 8.7 8.6 10.2 6.1 7.8 4.4 4.1 5.2 5.9 5.7 9.4 6.9 3.3 6.0 7.4 6.5 6.2 4.3 4.5 18.3 6.9 6.1 5.9 3.7 3.8 5.1 7.1 6.7 5.3 9.1 4.1 4.8 4.1 4.3 6.4 6.9 5.4 6.1 15.7 6.7 33.3 6.9 33.0 4.9 6.1 18.4 5.9 5.7 20.8 13.5 20.1 9.5 28.5 22.3 12.5 15.8 9.1 22.7 10.1 2.7 5.0 14.1 12.0 9.3 19.2 19.2 10.9 15.8 40.4 8.1 7.1 11.8 17.6 21.2 15.7 26.5 23.0 11.3 25.1 6.0 11.1 3.0 48.4 15.8 2.7 2.8 14.5 10.6 3.9 13.3 31.0 21.4 25.6 16.5 18.1 38.4 20.8 14.5 12.1 17.5 36.0 39.7 13.7 8.8 16.4 16.0 9.1 10.6 10.8 8.1 11.9 12.4 19.2 7.1 8.8 7.8 15.1 12.0 13.4 15.8 39.1 13.7 21.2 10.4 20.1 7.6 14.5 15.1 9.3 18.4 20.3 17.6 18.5 9.9 20.8 19.1 19.3 4.5 28.5 9.5 13.5 22.3 12.5 7.1 17.1 8.6 10.2 7.4 6.5 6.9 6.1 6.7 6.9 3.0 2.9 30.5 11.8 14.9 12.3 10.6 15.3 42.8 13.6 14.0 7.9 19.7 10.0 9.8 13.3 11.3 2.4 93.5 16.8 39.6 10.4 5.3 27.7 2.4 16.3 9.5 2.9 6.2 9.7 10.8 5.2 11.5 11.8 12.6 8.0 5.2 7.6 0.0 9.2 8.4 6.6 19.4 11.3 141.1 122.1 12.2 12.6 26.7 11.2 8.4 VRK2 ENSG00000028116 "Vaccinia related kinase 2" Q86Y07 2 57907651-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: AB_2680071" "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 18.7 17.7 10.9 21.9 28.3 14.9 16.1 2.4 15.1 15.6 13.5 27.3 16.3 9.9 18.4 16.7 26.8 13.2 10.9 21.6 14.4 8.9 12.4 15.2 15.6 19.5 29.2 13.5 14.2 20.0 16.1 18.7 16.1 18.7 15.7 15.6 9.3 20.5 17.6 21.5 12.8 12.9 20.1 19.0 20.1 13.5 12.5 31.2 13.6 17.4 16.7 23.0 18.1 19.4 19.7 17.0 21.6 21.3 11.3 12.2 9.2 14.2 9.5 1.1 6.3 7.1 13.1 19.7 13.2 13.2 9.1 9.3 19.4 15.1 17.4 17.4 11.6 15.0 10.9 13.8 14.4 13.7 31.2 9.3 19.6 7.7 13.8 11.3 16.6 11.7 7.2 17.2 14.6 21.1 10.9 26.2 2.4 19.2 11.2 15.2 8.2 0.1 12.7 12.0 22.6 4.8 19.0 4.8 11.8 15.1 11.7 3.8 0.1 20.9 12.5 10.5 10.9 8.8 10.2 14.6 0.2 30.3 8.2 0.2 16.5 13.0 9.3 7.4 20.6 15.0 13.7 16.8 21.6 10.1 21.3 12.2 19.7 9.8 11.8 16.6 19.0 7.4 9.5 6.0 11.3 20.6 17.0 11.5 9.2 10.9 28.3 2.4 15.1 14.4 8.9 29.2 13.5 18.7 31.2 20.8 9.1 14.1 11.3 8.8 1.0 17.1 10.2 30.8 15.9 17.4 0.0 19.7 13.3 22.0 16.8 15.0 2.9 46.7 22.8 18.5 8.5 8.1 16.3 6.8 17.1 0.0 6.3 4.9 17.7 6.5 5.5 21.4 10.1 49.5 4.3 4.6 21.8 7.8 5.6 7.1 3.6 6.5 13.7 8.3 12.6 7.3 16.2 12.7 7.1 12.2 VRK3 ENSG00000105053 "Vaccinia related kinase 3" Q8IV63 19 49976467-50025946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 77.2" "Group enriched" "Detected in all" 6 "Early spermatids: 469.4;Late spermatids: 1260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056489 Approved Supported Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA056489: AB_2683150" "unprognostic (2.09e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-3)" "unprognostic (1.23e-1)" "unprognostic (2.22e-3)" "unprognostic (9.78e-2)" "unprognostic (3.47e-1)" "unprognostic (8.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.83e-4)" "unprognostic (9.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "prognostic favorable (5.66e-4)" 9.7 11.9 9.2 9.4 12.7 10.7 8.3 12.0 14.1 8.9 13.4 11.9 9.3 13.4 15.7 10.8 8.4 18.0 12.2 7.4 9.3 11.1 16.7 16.2 8.5 13.4 10.4 9.9 11.2 11.5 7.1 11.8 10.7 9.8 9.4 11.7 14.2 14.3 8.5 11.8 7.7 17.3 7.5 11.0 12.8 10.9 77.2 9.1 24.7 14.1 6.0 12.9 9.9 8.0 24.5 19.7 47.3 20.9 33.5 30.1 18.1 16.0 16.7 12.3 13.2 16.3 15.1 12.8 11.6 13.9 17.3 19.1 8.9 18.0 19.4 8.3 11.2 12.1 12.0 11.4 9.9 14.0 16.9 23.4 15.1 10.1 15.4 12.3 18.8 26.6 13.5 14.9 10.0 10.6 15.5 14.2 21.3 18.3 29.0 12.4 6.8 25.4 12.7 6.6 28.6 14.4 20.5 12.9 24.8 14.7 17.0 13.8 6.7 11.4 14.0 12.6 11.4 12.9 20.1 10.7 17.7 10.3 7.1 9.0 18.8 23.9 10.2 14.2 11.7 12.1 37.0 17.8 32.4 23.8 18.8 19.1 24.5 21.7 22.7 19.7 21.9 22.1 20.4 47.3 33.5 20.9 18.8 30.1 18.1 9.2 12.7 12.0 14.1 9.3 11.1 10.4 9.9 9.8 9.1 6.0 29.4 27.3 13.1 6.0 34.9 7.1 20.4 56.2 26.1 14.0 135.5 38.6 26.6 25.3 469.4 15.8 62.6 23.3 28.7 31.8 13.8 24.2 17.4 37.6 29.7 30.2 21.4 25.2 25.0 1260.7 20.4 23.9 13.5 47.7 27.2 28.4 29.0 71.9 24.4 60.6 112.4 12.9 10.5 91.2 49.8 9.5 47.9 33.7 27.6 26.7 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573681-9593457 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Basal glandular cells: 165.0;Suprabasal keratinocytes: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004619, HPA068845" Approved Approved Nucleoli No No Nucleoli "CAB004619: AB_628447, HPA068845: AB_2686048" "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 6.9 3.5 2.0 26.1 2.1 6.6 27.4 5.3 1.6 12.8 18.0 2.5 15.4 3.7 21.9 14.3 22.1 12.4 20.2 23.0 2.0 2.2 6.8 19.3 10.2 10.9 1.8 1.2 11.1 4.4 4.9 6.1 42.7 4.7 17.0 4.7 5.9 12.8 17.8 12.0 33.3 10.4 22.9 2.4 8.0 12.5 28.3 2.0 35.9 12.0 26.8 26.4 19.8 14.7 8.5 0.1 6.4 0.0 2.1 7.8 0.6 14.4 5.6 21.5 11.9 18.9 9.5 42.6 17.9 13.8 10.0 10.0 10.2 17.8 33.9 6.7 7.8 9.4 17.5 14.7 6.9 12.8 12.1 12.0 13.3 9.0 6.8 2.0 20.1 13.3 3.1 7.5 4.7 16.6 10.4 6.2 13.2 21.6 23.6 17.4 3.4 20.5 10.9 32.4 10.0 6.4 19.8 16.9 7.3 7.9 30.5 8.1 10.6 12.1 14.3 8.7 26.8 9.0 9.6 7.1 18.1 12.6 7.3 14.2 5.5 16.5 44.8 7.7 11.1 12.6 0.0 0.0 6.4 2.0 0.0 0.2 8.5 2.0 3.3 0.1 3.6 0.1 1.6 0.1 2.1 0.0 0.1 7.8 0.6 2.0 2.1 5.3 1.6 2.0 2.2 1.8 1.2 4.7 2.0 47.6 26.9 13.5 165.0 156.6 1.8 53.3 66.2 49.5 56.9 40.1 0.0 78.4 11.6 22.0 18.2 13.0 34.2 23.3 11.8 154.6 38.6 75.9 6.9 86.3 14.7 1.6 58.5 9.2 1.6 29.5 10.9 8.4 16.9 2.8 32.0 9.3 20.6 25.7 10.3 6.7 4.4 6.5 22.1 42.6 52.9 167.1 114.8 13.1 37.4 55.3 WEE2 FLJ16107 ENSG00000214102 "WEE1 homolog 2" P0C1S8 7 141708353-141731271 "Enzymes, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" 21 "Distal tubular cells: 1.7;Proximal tubular cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA027418, HPA054280" Uncertain Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA027418: AB_10603144, HPA054280: " "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (2.33e-1)" "unprognostic (4.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (2.66e-1)" "unprognostic (6.07e-2)" "unprognostic (2.88e-3)" 0.6 0.1 0.5 0.3 1.0 0.0 0.4 0.8 0.6 0.6 0.1 0.0 0.7 0.0 1.3 0.7 1.6 1.3 0.5 0.6 1.3 0.1 0.3 1.6 0.6 1.2 1.1 0.0 1.0 0.0 0.3 0.0 0.9 0.0 0.7 2.8 0.4 0.0 0.8 0.4 0.8 1.3 2.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.2 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.4 0.1 0.1 0.0 0.3 1.0 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.3 0.5 1.6 1.2 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.2 0.1 1.7 1.1 0.5 0.0 0.4 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752593-911452 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 30.0 12.4 49.3 19.1 47.5 28.9 45.4 22.5 36.7 21.2 12.6 42.6 10.6 8.5 15.9 19.4 45.5 16.9 16.5 38.5 53.7 36.4 45.6 18.0 33.0 34.3 62.3 27.1 18.5 11.3 29.1 12.7 20.3 41.4 17.1 14.3 12.0 15.4 20.3 43.4 31.3 10.3 22.3 82.8 16.9 15.7 23.8 38.8 23.9 16.7 17.4 24.5 18.9 26.5 3.7 2.6 10.9 7.1 2.1 5.2 1.9 14.1 26.8 35.4 3.3 25.6 24.6 13.5 14.1 17.0 15.3 14.3 15.0 16.1 20.0 5.0 30.2 18.6 10.7 23.9 16.3 21.6 34.5 14.3 44.5 35.6 13.0 18.8 24.0 19.4 19.0 24.8 25.3 45.4 17.0 20.7 18.8 20.3 48.2 23.1 13.0 43.2 4.0 28.9 12.0 6.4 20.6 39.3 5.3 22.0 30.6 10.3 12.1 32.9 21.4 9.5 49.5 23.5 24.7 22.8 19.0 22.0 26.6 20.7 7.4 12.2 30.2 18.1 12.7 15.4 0.9 2.7 2.6 3.8 4.0 5.2 3.0 4.3 3.6 2.6 3.7 2.3 4.1 10.9 2.1 7.1 1.7 4.9 1.9 49.3 47.5 22.5 36.7 53.7 36.4 62.3 27.1 41.4 38.8 95.3 107.5 34.5 38.1 100.2 81.8 197.8 58.6 61.6 53.4 85.5 141.4 27.8 72.9 26.9 18.6 99.1 21.1 210.2 21.1 25.9 54.1 46.4 50.8 62.5 49.6 79.4 56.4 45.4 101.9 17.5 57.2 66.8 35.4 48.7 24.6 57.2 32.3 29.8 52.3 16.5 92.4 12.9 41.9 139.7 38.1 118.8 23.8 69.2 21.9 46.1 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.9;pancreas: 18.3;salivary gland: 19.5;skeletal muscle: 23.7" "Cell type enhanced" "Detected in many" 9 "Cone photoreceptor cells: 151.2;Rod photoreceptor cells: 101.2" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "Daudi: 11.5;Hep G2: 18.8;SCLC-21H: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol NA NA Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 0.0 0.7 3.9 0.9 3.8 0.0 1.2 9.5 7.2 0.7 7.5 7.4 1.3 1.5 2.1 6.6 0.1 21.9 4.0 4.2 0.0 0.0 0.0 0.0 2.6 0.0 18.3 0.8 7.5 0.9 4.9 4.8 19.5 5.5 23.7 3.0 6.2 1.6 1.1 0.5 3.0 1.5 0.0 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 0.3 0.0 4.4 4.0 2.9 8.2 0.0 0.0 5.6 0.0 0.0 0.0 0.0 1.6 0.1 11.5 1.5 0.0 0.8 0.2 6.5 0.0 0.0 0.0 7.5 0.0 3.5 18.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 7.3 0.0 0.0 6.0 0.1 0.1 7.3 4.4 0.2 0.0 0.0 9.3 0.0 0.7 23.9 9.4 1.5 6.5 0.6 0.8 0.8 1.3 0.1 0.0 3.1 0.1 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.1 1.1 57.3 56.7 30.6 5.3 9.1 0.0 151.2 11.9 0.0 11.7 0.9 0.5 34.4 0.0 8.0 5.6 1.1 12.9 0.0 0.0 2.9 1.6 31.2 0.6 1.0 1.9 0.9 0.0 1.7 1.0 57.9 60.6 3.3 42.1 5.6 0.7 101.2 12.9 4.4 0.4 6.6 4.8 13.0 0.0 51.8 6.4 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 31.6;testis: 26.7" "Cell type enhanced" "Detected in many" 15 "Cardiomyocytes: 178.0;Spermatogonia: 48.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.1;T-cells: 1.9" "Cell line enhanced" "Detected in some" "AF22: 5.9;AN3-CA: 4.5;HAP1: 6.8;NTERA-2: 11.9;SiHa: 5.8;SuSa: 5.3;U-2 OS: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles NA NA Vesicles "HPA077678: AB_2686850" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.9 5.0 3.9 0.9 4.3 0.8 1.7 3.0 3.6 1.5 0.7 1.7 13.9 1.0 1.3 31.6 1.1 1.8 1.1 1.5 3.9 3.4 2.8 8.7 0.9 1.0 2.3 3.0 5.7 0.9 2.2 14.0 1.2 3.9 2.2 0.7 1.3 1.2 4.8 0.7 0.9 0.7 1.5 3.3 1.0 1.2 26.7 3.5 0.0 1.7 0.0 0.8 1.3 1.9 1.1 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.0 5.9 4.5 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 6.8 0.1 0.2 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.2 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 2.8 0.8 0.0 1.2 0.2 1.9 1.8 5.8 0.0 0.7 5.3 0.5 0.0 0.3 0.0 5.2 0.0 1.2 0.0 4.0 0.0 1.6 0.0 2.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.1 1.9 0.4 0.1 0.1 0.0 0.0 0.0 0.1 3.9 4.3 3.0 3.6 3.9 3.4 2.3 3.0 3.9 3.5 0.0 2.9 0.8 4.6 3.3 24.5 178.0 2.5 0.0 5.7 7.0 13.7 0.2 5.0 1.4 4.2 3.1 0.0 0.0 0.0 0.3 3.1 4.8 5.8 41.5 0.1 33.4 0.0 17.8 0.6 14.6 14.7 0.5 0.0 0.0 0.0 20.7 0.3 0.0 41.1 3.1 40.9 6.5 3.3 30.2 48.2 1.0 0.1 0.0 0.0 1.1 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780678-42796936 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1;ovary: 14.6" "Group enriched" "Detected in some" 7 "Distal tubular cells: 135.9;Mucus-secreting cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.9;K-562: 22.2;TIME: 21.4;WM-115: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.1 0.0 0.8 5.8 0.2 0.0 2.6 0.6 0.3 0.7 12.9 0.4 0.4 2.1 0.2 2.8 8.7 0.5 1.0 0.2 2.6 0.0 28.1 0.2 0.4 0.1 0.1 0.3 14.6 1.0 0.0 2.4 0.0 1.7 11.1 11.7 12.2 1.4 1.2 0.0 0.5 3.3 0.4 0.8 0.1 2.6 0.4 0.2 0.0 0.0 0.2 2.0 0.3 0.4 0.4 0.0 0.0 0.3 0.0 1.0 0.0 1.2 0.6 0.2 0.0 0.2 0.1 2.9 7.4 2.9 2.8 0.9 0.4 0.5 0.2 4.4 19.9 0.7 0.0 0.1 0.2 4.8 0.4 1.0 0.0 0.0 2.9 4.7 0.0 0.4 2.5 0.4 4.0 1.2 1.4 0.2 0.2 22.2 0.7 0.0 0.6 0.0 0.5 0.2 1.2 5.1 0.3 0.7 0.0 0.0 0.3 0.0 0.1 0.0 0.1 1.0 2.7 1.4 1.6 21.4 0.2 1.9 0.2 0.1 3.6 3.1 0.7 0.0 1.2 14.5 0.0 0.3 0.0 0.0 0.0 0.7 0.4 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.3 2.6 0.0 0.1 0.3 1.7 0.2 0.0 1.1 0.0 0.1 0.0 0.2 0.7 2.5 5.3 1.2 7.0 0.0 0.0 135.9 0.0 0.0 0.0 1.1 0.0 0.2 0.1 0.0 6.5 4.6 0.0 0.0 0.0 12.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.1 2.9 0.4 0.5 0.3 0.0 0.3 0.7 0.8 0.4 0.0 0.0 13.3 0.1 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342738-86478420 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 15.4 9.1 9.7 15.6 14.1 5.2 20.9 8.5 9.5 11.5 16.9 7.5 21.1 8.7 11.9 19.3 11.7 7.2 22.0 40.7 8.7 8.5 16.9 37.2 10.2 15.9 10.0 7.8 10.1 11.3 40.7 7.3 15.6 12.7 17.8 11.3 8.9 11.8 9.4 58.0 13.8 13.0 18.4 9.9 19.1 11.4 10.4 9.5 11.1 11.2 18.0 12.5 14.5 12.3 3.7 2.6 6.5 2.8 2.9 10.4 2.3 22.6 10.6 7.4 5.2 9.3 9.2 6.8 8.3 8.8 6.6 7.9 7.5 14.0 9.7 5.6 14.1 9.2 19.5 10.3 13.3 11.4 12.1 8.3 11.2 9.4 17.5 6.8 4.4 5.8 8.3 16.9 7.2 13.4 10.2 29.1 11.5 5.9 11.5 11.1 11.3 10.6 3.4 4.5 31.7 12.0 7.0 8.9 8.6 14.8 17.3 2.2 5.2 8.2 41.6 8.8 16.8 12.4 4.2 33.4 9.9 11.7 10.4 4.2 13.6 8.3 10.0 12.2 0.8 7.5 6.5 2.8 4.8 7.2 2.4 6.0 3.7 8.7 7.1 1.9 3.6 10.4 6.3 1.7 2.9 2.8 2.6 8.0 2.3 9.7 14.1 8.5 9.5 8.7 8.5 10.0 7.8 12.7 9.5 23.8 19.9 7.5 24.5 31.8 24.5 71.8 45.9 10.7 17.0 27.9 55.0 21.8 36.5 16.7 18.9 25.5 14.8 0.0 32.4 2.7 17.3 35.8 3.5 77.6 43.8 38.1 22.8 64.4 64.9 9.4 30.0 17.5 28.7 10.8 25.5 21.3 37.0 14.0 34.3 38.8 48.9 6.5 13.0 10.9 14.7 34.5 19.2 20.3 18.3 32.8 WWP2 AIP2 ENSG00000198373 "WW domain containing E3 ubiquitin protein ligase 2" O00308 16 69762306-69941741 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-3)" "unprognostic (2.86e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-2)" "unprognostic (5.22e-2)" "unprognostic (1.14e-1)" "unprognostic (7.50e-2)" "unprognostic (2.08e-2)" "unprognostic (9.81e-2)" "prognostic favorable (5.87e-11)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.62e-1)" 21.8 27.0 18.0 21.5 24.4 31.0 19.1 19.1 29.0 18.9 22.8 29.7 19.6 23.9 31.9 17.2 21.3 23.9 19.3 12.2 18.0 17.4 26.9 14.9 22.7 20.6 20.0 15.9 22.5 27.3 34.1 15.9 24.1 21.7 17.7 20.7 28.1 29.0 19.4 17.6 24.4 25.3 15.3 19.7 26.2 24.1 17.0 18.4 25.2 19.7 14.6 37.7 16.5 17.3 7.1 8.2 28.0 15.5 4.6 9.5 8.1 12.6 12.8 8.4 8.7 7.1 5.9 12.8 8.5 9.9 14.7 15.5 11.9 9.8 14.8 9.3 14.9 8.1 15.2 11.0 12.9 11.2 6.9 9.5 8.2 7.8 20.4 13.3 14.4 12.2 8.7 9.6 20.1 14.1 8.3 13.5 12.8 12.4 8.4 9.4 22.4 7.9 16.2 11.7 10.6 5.7 17.8 7.0 25.1 14.3 12.4 10.4 11.4 36.4 10.5 7.8 5.7 16.4 17.9 13.4 11.5 16.9 16.1 10.2 19.4 12.9 22.3 12.4 12.3 20.3 18.2 10.0 15.6 9.5 12.9 7.3 6.4 7.1 7.6 8.2 7.1 7.5 5.1 28.0 4.6 15.5 4.0 6.3 8.1 18.0 24.4 19.1 29.0 18.0 17.4 20.0 15.9 21.7 18.4 8.9 32.3 13.8 7.1 6.5 8.7 8.0 20.4 26.8 14.8 14.0 9.8 8.0 1.7 10.3 20.1 10.8 24.8 23.3 17.3 7.2 6.1 7.5 20.8 12.1 11.3 9.5 16.1 14.7 24.8 21.3 9.5 15.1 10.1 13.6 14.2 11.0 14.2 19.0 8.1 8.4 6.0 12.9 22.8 5.6 6.1 5.3 16.7 12.5 14.3 8.6 ZC3HAV1 "FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2" ENSG00000105939 "Zinc finger CCCH-type containing, antiviral 1" Q7Z2W4 7 139043520-139109719 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "T-cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047818, HPA059096" Approved Supported "Golgi apparatus,Cytosol" NA NA Cytosol "Golgi apparatus" "HPA047818: AB_10962642, HPA059096: AB_2683903" "unprognostic (1.68e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-1)" "unprognostic (1.51e-2)" "unprognostic (3.92e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (8.77e-7)" "unprognostic (5.40e-2)" "unprognostic (3.08e-1)" "unprognostic (2.55e-2)" "unprognostic (3.72e-1)" "unprognostic (5.41e-2)" "unprognostic (3.31e-3)" "prognostic favorable (6.86e-4)" "unprognostic (6.47e-2)" "unprognostic (1.99e-1)" "unprognostic (7.84e-2)" 14.3 14.8 6.8 19.8 6.6 52.6 13.8 1.6 5.6 11.2 11.5 6.7 10.8 6.9 10.0 10.9 14.2 9.5 10.4 7.0 5.4 7.2 11.2 13.1 17.2 44.4 7.5 4.0 10.6 11.0 9.8 11.4 8.5 8.6 11.2 10.2 9.3 16.9 11.5 3.8 9.5 14.8 10.8 9.0 22.6 9.6 7.8 6.9 43.9 18.2 8.8 26.1 10.8 29.0 16.3 7.0 28.8 11.9 15.6 27.9 11.8 11.4 14.2 2.0 11.8 18.8 18.1 8.6 13.0 10.0 22.8 23.5 10.2 15.0 10.1 12.3 20.8 19.7 13.1 15.9 15.5 13.0 17.9 5.9 20.1 14.4 12.6 10.8 23.3 18.7 18.4 9.9 25.9 5.8 8.5 16.9 15.3 17.0 11.4 9.7 10.9 19.2 27.2 8.0 8.8 8.7 22.8 7.1 9.8 15.6 14.5 3.7 7.5 20.1 14.2 17.3 4.8 8.3 14.6 21.3 4.9 7.1 13.3 10.7 8.7 9.1 23.8 10.9 21.8 11.5 28.8 8.2 11.9 19.4 10.6 24.6 14.3 27.9 23.5 6.4 16.3 27.3 26.4 22.1 15.6 11.9 7.0 24.2 11.8 6.8 6.6 1.6 5.6 5.4 7.2 7.5 4.0 8.6 6.9 23.8 44.5 82.7 23.7 25.4 2.1 4.4 30.6 28.1 20.5 50.6 3.9 10.5 8.3 17.4 2.2 46.7 36.0 23.3 18.3 17.5 51.6 34.7 31.2 29.9 30.5 0.0 51.0 46.1 44.1 1.2 17.3 62.3 37.1 37.9 31.3 15.0 19.2 26.4 25.1 31.0 0.7 12.9 57.9 0.7 0.7 19.4 1.9 124.6 27.3 23.0 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999030-75110994 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 80.1" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 4.5;T-reg: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;monocytes: 1.4;T-cells: 5.2" "Cell line enhanced" "Detected in many" "HMC-1: 54.8;MOLT-4: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved NA NA "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favorable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 10.0 9.5 13.4 8.1 13.7 5.2 16.6 6.3 16.5 13.2 12.5 8.1 6.7 8.3 10.7 9.1 28.2 10.0 11.3 9.1 11.6 14.6 5.6 12.8 12.8 8.7 9.1 9.4 10.1 6.1 12.2 6.2 9.7 7.8 9.1 10.8 7.2 7.5 7.5 58.6 14.5 11.2 10.1 8.8 2.8 11.8 21.6 4.9 80.1 21.4 16.9 13.3 14.0 15.5 0.2 0.8 4.5 1.4 0.0 5.2 0.3 3.2 4.7 8.1 8.4 8.7 6.8 28.1 3.9 5.5 5.4 5.3 7.6 10.0 0.8 3.0 8.5 5.2 7.7 3.9 5.4 4.3 7.8 2.2 16.8 1.5 13.8 6.9 8.0 54.8 6.1 4.5 5.6 4.6 9.6 8.8 20.7 8.0 2.6 4.1 30.8 39.2 29.6 11.3 9.3 5.1 17.4 3.0 5.1 7.6 9.1 10.9 11.7 6.2 8.3 2.2 7.0 21.9 7.7 6.0 3.7 6.5 6.6 2.3 15.6 15.8 9.3 4.9 9.0 3.8 4.5 1.4 0.9 0.2 1.1 1.3 0.2 1.5 0.2 0.8 0.0 0.0 0.2 1.2 0.0 1.1 0.0 5.2 0.3 13.4 13.7 6.3 16.5 11.6 14.6 9.1 9.4 7.8 4.9 8.9 11.8 0.8 13.7 14.2 10.6 15.7 15.3 14.7 12.5 3.5 49.1 5.5 0.0 6.8 17.8 23.3 12.9 0.0 10.9 9.4 10.4 10.2 35.8 11.6 8.3 3.2 19.0 9.2 5.9 10.1 6.4 4.0 13.5 7.2 14.4 11.9 14.8 11.5 3.9 5.1 5.5 0.0 7.6 11.3 16.1 17.1 3.8 6.4 9.8 25.7 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284307-30367692 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 5.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved Uncertain "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Nucleoplasm, Vesicles" "Nucleoli fibrillar center" "HPA072244: AB_2732197" "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favorable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favorable (8.71e-4)" "unprognostic (8.67e-2)" 7.8 8.0 10.0 9.3 10.6 9.7 16.2 12.8 10.0 5.8 16.1 10.5 7.6 11.3 7.7 9.7 14.2 5.2 8.7 8.4 9.6 6.1 19.3 24.0 7.9 12.0 10.0 7.4 5.8 14.0 8.0 9.9 9.6 11.0 7.0 14.3 5.8 10.5 13.7 17.5 11.5 12.7 8.3 10.5 9.2 12.4 20.6 9.1 7.9 13.3 9.8 10.9 9.4 11.8 1.3 5.8 1.4 1.1 0.7 2.4 0.5 6.7 2.5 2.0 1.8 2.3 1.6 10.7 2.6 2.7 2.9 3.9 1.2 11.3 7.1 6.8 2.1 7.5 6.6 6.7 4.4 3.1 6.9 6.1 4.4 5.2 3.3 1.2 3.4 8.4 2.5 7.5 2.0 4.9 3.0 2.4 5.5 5.4 14.2 3.1 2.6 6.9 9.0 4.7 6.7 3.1 6.0 4.4 12.1 8.7 14.6 7.0 6.6 5.2 22.0 4.3 12.4 5.9 13.8 2.7 2.8 4.8 2.7 5.4 24.3 20.8 9.3 3.1 7.4 4.1 0.5 0.9 1.1 1.0 0.9 1.5 1.3 1.2 1.4 0.8 0.8 0.7 1.1 1.4 0.7 1.1 5.8 2.4 0.5 10.0 10.6 12.8 10.0 9.6 6.1 10.0 7.4 11.0 9.1 8.9 6.7 5.2 5.8 14.2 11.0 3.2 17.8 2.7 4.5 15.7 39.3 7.5 6.6 4.9 4.3 4.5 42.5 0.0 8.9 8.0 4.4 5.5 3.5 33.4 9.4 1.6 30.1 9.2 18.9 7.6 2.6 11.2 11.8 9.0 14.5 4.3 6.7 14.4 2.1 26.0 5.7 6.5 7.2 20.9 7.9 16.6 9.6 8.7 19.6 10.8 ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827835-186849208 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 17.4" "Group enriched" "Detected in some" 5 "Early spermatids: 41.7;Late spermatids: 15.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.1;U-138 MG: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (2.00e-1)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.3 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.4 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.6 0.0 0.2 0.0 0.0 0.0