Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019021-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 102.3" "Cell type enhanced" "Detected in many" 8 "Cytotrophoblasts: 207.2;Syncytiotrophoblasts: 315.1" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "A-431: 345.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 93000000 "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 16.2 8.4 4.9 7.5 6.8 0.1 39.8 5.1 8.5 13.8 7.8 3.3 10.7 3.6 8.2 11.7 15.6 8.8 8.5 4.8 6.8 2.7 7.6 23.5 14.2 2.3 4.1 3.9 10.4 10.1 1.8 2.1 102.3 5.6 10.9 6.7 9.2 15.4 12.9 10.7 32.5 6.3 15.5 3.5 3.3 7.8 5.5 5.9 3.2 12.8 15.5 8.0 10.2 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.9 4.4 1.1 1.5 7.1 4.4 1.2 3.4 4.6 2.1 1.6 0.8 3.7 0.2 0.8 2.9 9.0 13.9 0.0 15.3 2.5 0.1 0.2 0.0 1.9 0.2 1.8 0.0 0.0 2.1 14.0 5.3 28.6 3.1 0.2 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.3 1.3 2.2 0.0 0.6 0.0 2.6 3.7 0.0 1.3 2.9 3.5 0.7 1.2 0.3 0.8 1.0 1.9 0.5 14.9 3.2 0.0 0.3 0.2 2.6 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 6.8 5.1 6.6 6.8 2.7 4.1 3.9 5.6 5.9 89.3 37.5 4.2 67.7 76.2 1.5 7.3 53.5 16.0 59.1 21.0 5.9 207.2 0.0 30.6 4.6 10.9 15.9 23.3 21.0 36.6 45.3 37.8 0.0 77.4 24.2 0.0 4.1 6.7 7.0 2.2 118.8 1.3 16.9 2.8 25.3 106.1 41.7 17.3 125.5 14.0 2.3 77.6 23.1 1.6 2.7 78.5 315.1 0.0 20.0 46.4 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078259-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Endothelial cells: 100.3;Ito cells: 200.7;Muller glia cells: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 32.5;TIME: 36.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004028 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 7400000 "Plasma membrane" "CAB004028: AB_2212507" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 19.7 6.2 1.8 4.4 3.1 0.4 20.5 1.1 2.2 11.4 6.0 1.8 11.5 2.3 28.8 10.2 5.2 9.5 6.2 12.1 2.3 1.7 7.8 10.4 13.2 14.1 3.1 2.9 6.0 8.1 8.0 6.8 34.5 3.9 9.5 1.4 27.6 7.1 10.3 5.3 3.0 3.8 7.7 2.6 4.4 4.2 5.3 1.2 0.5 20.0 5.3 3.0 4.4 12.0 0.1 0.1 0.7 0.0 0.2 0.2 0.1 0.0 0.0 1.7 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 3.8 0.0 0.0 0.3 0.0 0.0 0.2 0.2 32.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.8 3.1 1.1 2.2 2.3 1.7 3.1 2.9 3.9 1.2 0.0 8.2 7.5 0.4 2.3 7.4 4.8 0.0 6.7 30.7 0.0 0.0 0.1 0.0 0.5 0.8 100.3 0.0 0.0 0.0 0.1 1.9 0.4 2.3 1.3 0.4 0.0 0.0 200.7 14.5 0.6 0.0 1.0 6.8 0.0 0.0 229.2 0.3 0.0 0.4 0.0 6.0 0.0 1.4 0.2 0.2 2.4 0.1 0.0 0.0 0.4 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related tyrosine kinase 1" P17948 13 28300344-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "placenta: 155.3" "Cell type enhanced" "Detected in many" 16 "Extravillous trophoblasts: 778.4;Ito cells: 284.2;Syncytiotrophoblasts: 942.6" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.1;naive B-cell: 3.7;neutrophil: 2.1" "Group enriched" "Detected in many" 5 "B-cells: 3.7;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "BJ: 17.4;BJ hTERT+: 13.8;HMC-1: 86.4;HUVEC TERT2: 15.6;WM-115: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 54000 "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 18.9 4.0 9.9 4.0 14.3 1.2 13.5 8.0 15.9 7.1 4.6 3.5 1.7 3.5 7.2 2.2 3.4 4.0 6.9 18.3 11.4 7.3 10.3 7.6 12.3 2.5 10.3 3.2 5.1 5.4 13.4 3.7 155.3 13.8 5.1 3.1 9.1 3.0 5.0 12.5 2.6 3.4 7.3 9.6 7.2 4.6 6.8 10.2 0.0 19.1 3.8 2.8 7.6 9.2 3.7 0.5 2.1 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 17.4 13.8 6.3 3.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.6 0.0 11.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 86.4 0.1 0.0 0.0 0.2 0.0 15.6 1.4 0.4 0.0 0.0 0.0 1.0 0.8 9.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 11.4 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.5 0.2 0.0 0.1 0.0 31.0 0.2 0.1 0.1 0.1 0.1 0.0 1.1 0.1 0.1 0.0 3.7 0.4 0.4 2.1 0.2 0.1 0.5 0.2 0.2 9.9 14.3 8.0 15.9 11.4 7.3 10.3 3.2 13.8 10.2 0.0 8.9 2.2 0.5 3.7 5.9 12.6 5.1 2.7 1.2 0.0 3.9 155.4 1.7 0.0 116.6 192.1 0.0 0.0 0.0 778.4 17.5 1.1 1.1 2.1 28.1 1.6 0.0 284.2 16.1 130.7 17.3 5.3 0.0 0.0 0.0 172.0 0.0 0.0 45.6 0.0 7.3 90.5 6.6 12.9 2.8 4.3 942.6 2.9 0.0 0.5 FLT4 "PCL, VEGFR3" ENSG00000037280 "Fms related tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 56.3" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 31.7;Ito cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "MAIT T-cell: 7.7" "Lineage enriched" "Detected in single" 35 "T-cells: 7.7" "Cell line enhanced" "Detected in some" "AN3-CA: 8.3;BEWO: 10.1;HEK 293: 12.5;HUVEC TERT2: 8.1;JURKAT: 10.0;T-47d: 11.9;TIME: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 270000000 "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 14.8 7.1 1.6 4.9 6.0 0.7 28.5 1.3 2.7 6.3 7.3 1.9 2.1 3.1 7.3 6.2 5.7 9.2 5.3 6.4 1.7 0.9 11.7 10.2 14.1 23.6 2.0 0.8 5.8 2.3 2.3 6.2 56.3 2.1 4.9 1.4 6.7 3.3 4.4 4.8 2.8 4.7 4.7 1.5 14.5 2.4 3.5 2.0 0.3 19.4 4.4 2.3 6.1 14.7 0.0 0.1 0.2 0.0 0.0 7.7 0.2 0.1 2.0 2.7 8.3 0.0 0.0 10.1 0.2 0.1 0.0 0.0 0.3 0.3 0.2 0.8 0.1 0.5 0.3 2.8 0.1 0.2 0.1 12.5 1.0 0.4 0.4 0.1 7.4 0.2 0.2 0.0 0.1 0.3 0.3 8.1 10.0 0.3 0.3 1.7 4.5 0.1 0.4 5.8 0.2 0.5 6.5 0.0 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.0 2.7 11.9 0.2 12.6 0.1 5.9 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.9 0.0 7.7 0.0 0.4 1.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 1.6 6.0 1.3 2.7 1.7 0.9 2.0 0.8 2.1 2.0 0.0 1.7 0.9 0.2 0.8 0.0 4.5 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.2 9.2 0.0 0.0 0.0 31.7 0.6 0.2 2.3 0.4 1.1 0.0 0.0 65.1 5.7 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 4.3 1.0 0.8 0.7 0.0 0.1 RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "intermediate monocyte: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles NA NA Vesicles "HPA077399: " "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (4.76e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-2)" "unprognostic (3.69e-2)" "unprognostic (5.60e-3)" "unprognostic (4.54e-3)" "unprognostic (4.51e-2)" "unprognostic (1.02e-1)" "unprognostic (7.81e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.81e-2)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (4.22e-2)" 12.7 3.7 6.2 11.5 9.3 0.3 17.7 3.5 6.2 21.8 10.8 6.1 6.7 5.6 13.0 10.4 17.5 10.6 17.2 15.9 7.0 2.8 8.2 3.8 17.8 4.1 6.9 4.9 18.8 9.6 9.8 4.3 26.5 7.3 19.6 5.5 15.9 20.1 13.5 13.4 22.4 7.5 14.6 5.8 6.1 9.2 7.1 3.1 1.2 11.2 15.7 10.1 16.0 19.4 0.0 0.5 0.0 1.7 0.0 0.4 0.0 4.3 7.0 4.0 9.3 15.9 19.7 13.3 11.9 22.5 8.4 8.1 9.5 15.2 0.2 5.0 12.7 4.3 13.8 2.0 8.0 1.4 0.1 2.2 0.1 7.0 2.6 17.8 0.1 7.7 16.4 8.5 21.8 3.6 15.0 12.8 0.0 1.6 0.2 13.3 24.2 0.0 1.4 3.6 9.1 6.0 0.1 4.8 0.3 9.4 4.4 0.1 1.0 3.4 13.2 7.4 5.2 20.4 1.5 13.3 13.4 9.4 10.3 3.2 0.1 0.2 0.1 9.3 0.2 20.9 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.2 9.3 3.5 6.2 7.0 2.8 6.9 4.9 7.3 3.1 17.9 3.8 0.0 8.9 6.1 0.9 8.1 20.4 1.4 6.8 8.7 62.8 14.0 0.0 19.1 0.5 9.5 5.3 0.0 6.9 14.1 18.2 19.2 0.0 2.6 1.9 0.0 0.0 6.2 0.3 0.9 18.1 0.3 15.1 0.0 8.3 5.7 19.4 7.2 13.1 2.1 4.3 12.9 12.9 0.2 2.5 4.8 25.6 0.5 2.9 9.4 EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519328 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" NA NA 67000 "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" 39.0 26.9 35.5 25.3 27.8 13.2 19.3 22.2 41.0 25.7 16.7 35.7 16.2 11.4 21.8 21.3 19.6 14.1 19.3 18.9 40.7 26.0 21.0 19.1 24.4 30.7 36.2 11.2 22.4 10.9 17.0 14.6 22.8 20.3 22.5 15.5 25.7 24.3 16.4 30.9 18.1 19.3 18.2 36.8 33.8 15.2 32.4 33.1 25.0 20.3 23.4 32.1 25.3 17.0 16.1 10.8 14.9 12.2 10.7 18.7 8.0 14.8 4.4 9.6 9.0 22.3 22.3 24.0 10.4 16.4 8.5 12.6 6.1 8.3 30.3 10.7 16.2 17.4 14.1 12.4 9.9 12.9 34.2 7.8 26.9 7.6 7.2 21.0 15.3 24.9 18.1 9.2 14.9 20.3 14.8 15.8 10.8 16.7 13.8 12.9 7.3 12.3 8.3 13.2 10.4 7.2 10.1 14.6 6.6 11.2 18.4 6.6 9.2 12.3 22.0 17.9 27.7 8.9 10.9 21.9 7.9 8.6 15.9 8.6 16.5 16.7 20.4 11.8 17.4 7.0 14.9 10.1 11.6 10.1 10.7 15.3 16.1 12.2 15.6 10.8 10.0 7.3 10.5 7.8 10.7 12.2 7.1 18.7 8.0 35.5 27.8 22.2 41.0 40.7 26.0 36.2 11.2 20.3 33.1 32.8 43.7 52.2 25.1 38.1 16.1 53.7 20.4 26.8 21.6 41.8 29.5 17.7 16.6 12.4 21.7 42.7 20.1 0.0 16.4 15.6 33.6 48.2 23.2 33.7 65.6 27.0 27.6 74.9 76.1 45.1 60.9 39.3 97.8 33.3 31.1 41.6 19.4 24.1 45.3 22.7 26.0 38.8 31.5 70.5 36.4 44.5 23.8 47.5 19.5 42.3 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620158-15882329 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Sertoli cells: 394.5;Smooth muscle cells: 265.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 16.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 56.9;HHSteC: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 52.6 5.9 7.9 7.4 10.7 0.1 37.3 7.9 7.6 28.7 24.9 9.5 13.5 16.6 39.1 28.5 12.2 16.9 25.4 16.3 8.4 6.8 25.4 16.3 12.7 7.0 12.6 6.6 23.4 6.6 6.4 4.4 23.4 10.9 24.4 24.2 23.3 12.0 19.0 12.7 9.8 26.2 36.0 13.5 11.1 14.2 12.1 11.8 0.1 15.9 9.5 2.8 33.5 40.1 1.0 4.4 3.6 16.7 0.7 0.9 1.2 13.6 8.3 8.3 0.3 56.9 40.5 11.7 15.9 13.0 7.6 10.2 7.1 21.0 0.0 0.5 29.9 25.3 3.5 2.4 2.0 11.5 0.0 2.7 1.2 2.6 7.3 49.2 0.9 0.0 35.7 9.2 20.1 25.7 9.9 3.8 0.0 0.0 0.0 36.6 3.7 0.0 0.6 1.1 10.6 6.7 0.0 24.1 0.1 21.7 19.7 0.6 1.0 4.6 2.6 19.6 1.4 7.5 0.9 6.1 12.2 3.2 7.0 6.5 0.7 0.0 0.0 7.1 2.2 34.7 0.0 2.2 0.2 0.2 8.7 0.1 1.0 0.8 0.3 4.4 0.3 0.9 0.4 3.6 0.7 16.7 0.3 0.1 1.2 7.9 10.7 7.9 7.6 8.4 6.8 12.6 6.6 10.9 11.8 11.9 128.1 6.4 32.5 15.0 9.0 26.6 45.9 123.1 67.1 22.7 62.8 28.6 51.4 61.2 44.8 38.3 132.6 0.0 60.3 5.2 39.1 23.0 5.8 29.8 50.7 6.4 36.8 43.0 42.7 39.2 124.8 32.7 33.7 10.0 53.1 11.3 68.7 76.3 41.1 88.2 140.5 394.5 265.9 10.8 3.1 11.4 17.6 5.7 61.9 92.1 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Cholangiocytes: 180.9;Enterocytes: 163.1;Paneth cells: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 5.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.3" "Cell line enhanced" "Detected in many" "Hep G2: 30.9;MCF7: 20.2;OE19: 31.8;RT4: 24.2;SK-BR-3: 28.4;SK-MEL-30: 37.9;T-47d: 31.5;WM-115: 40.2" "Low region specificity" "Detected in many" "CAB025331, HPA045396" Uncertain Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 420000 "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312" "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 1.1 1.4 11.6 12.6 16.5 0.6 26.8 2.0 16.7 6.8 40.5 40.3 12.0 37.7 2.8 7.5 29.4 5.7 22.9 3.4 18.6 9.0 16.5 33.9 13.4 0.5 23.5 9.3 0.9 21.5 11.4 1.0 15.4 14.9 16.8 29.7 5.5 36.8 22.3 1.1 30.7 41.3 3.2 27.4 0.5 32.9 1.2 23.8 0.0 4.5 7.4 8.5 11.8 14.4 0.9 0.7 5.3 0.6 1.2 1.2 0.2 10.0 0.6 0.8 0.3 0.0 0.0 16.4 0.8 1.9 1.1 1.1 5.5 18.2 0.0 0.2 0.2 0.1 8.6 1.2 1.9 0.6 0.2 0.8 0.0 0.3 30.9 0.0 0.0 0.1 0.4 2.5 0.2 0.0 0.2 0.0 0.1 0.7 0.3 0.1 20.2 0.1 0.3 2.8 31.8 0.4 0.1 1.9 0.5 2.1 24.2 0.9 0.3 0.7 28.4 37.9 2.7 31.5 0.1 0.0 0.1 1.1 0.6 0.1 0.2 0.1 0.1 0.1 0.0 40.2 5.3 0.4 0.8 0.9 0.4 0.4 0.4 0.7 0.3 0.3 0.9 0.6 1.2 3.3 1.2 0.6 0.7 0.8 0.2 11.6 16.5 2.0 16.7 18.6 9.0 23.5 9.3 14.9 23.8 110.2 61.2 1.3 13.0 16.3 1.5 1.4 180.9 21.4 61.4 33.2 2.0 44.4 1.7 41.9 0.9 2.2 163.1 0.0 77.1 73.6 2.7 83.4 1.1 83.9 5.5 0.0 89.5 6.7 1.9 0.0 1.4 1.7 52.3 2.8 134.3 11.3 75.9 165.5 0.0 31.8 1.1 6.5 1.7 2.4 2.3 32.2 84.1 1.5 124.3 62.5 EREG ER ENSG00000124882 Epiregulin O14944 4 74365143-74388751 "Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.1;tongue: 44.0" "Cell type enhanced" "Detected in many" 13 "Enterocytes: 44.2;Kupffer cells: 56.9;Macrophages: 122.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 60.3;CAPAN-2: 17.1;hTEC/SVTERT24-B: 19.0;U-2197: 41.1;U-87 MG: 70.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054373 Approved Vesicles "Secreted to blood" NA NA 46000 Vesicles "HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" 2.2 0.0 0.1 4.6 0.3 52.1 1.2 0.0 0.1 5.0 1.2 0.1 0.0 0.0 0.1 0.5 15.3 1.2 7.3 0.8 0.0 0.0 0.4 0.2 6.7 1.1 0.0 0.2 0.5 0.1 0.0 0.0 2.0 0.3 0.2 1.6 0.1 1.6 0.0 0.5 10.7 1.0 1.3 0.1 1.9 0.3 0.3 0.0 0.2 0.0 44.0 7.2 4.1 4.6 0.6 1.3 2.6 1.2 0.4 0.3 0.3 0.3 9.1 0.0 0.0 0.9 1.5 0.0 2.0 60.3 0.6 0.3 7.1 17.1 0.0 10.1 0.0 4.6 0.5 0.0 13.1 0.6 0.0 0.0 0.2 0.3 0.2 0.2 0.0 0.0 0.9 4.6 19.0 10.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 41.1 0.0 0.0 0.0 0.0 70.5 0.0 0.0 1.9 1.2 2.6 0.3 1.0 0.2 0.2 0.2 0.2 1.3 0.6 0.3 0.2 1.0 0.4 0.2 0.4 0.2 0.3 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 6.0 11.1 1.9 4.9 4.7 0.0 15.7 2.5 4.0 29.6 0.0 0.0 0.5 0.0 0.0 3.1 2.2 44.2 0.0 0.2 0.7 6.1 2.0 6.9 0.0 28.2 0.0 3.5 0.6 56.9 0.4 0.3 122.8 6.8 29.7 24.7 0.0 0.4 17.5 0.0 0.1 0.0 0.0 2.2 0.5 0.2 8.2 0.6 1.0 27.7 6.7 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.9" "Cell type enhanced" "Detected in many" 6 "Basal glandular cells: 79.7;Glandular cells: 69.7;Syncytiotrophoblasts: 82.5;Urothelial cells: 65.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 7.4" "Cell type enriched" "Detected in single" 20 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enriched" "Detected in some" 5 "OE19: 193.7" "Region enhanced" "Detected in some" "cerebellum: 9.3" "Low region specificity" "Detected in all" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 2.9 0.1 0.1 2.8 0.6 0.0 16.1 7.4 1.2 6.7 12.7 0.3 25.0 6.7 2.6 8.1 53.9 14.5 16.3 0.8 0.2 0.1 23.4 5.2 12.3 0.1 0.1 0.4 3.1 20.5 5.8 3.7 42.6 1.6 10.2 6.4 0.7 14.0 25.5 0.5 19.1 12.4 2.0 0.1 0.3 7.2 2.3 0.3 0.5 8.5 6.5 17.2 7.2 11.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.6 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.9 2.8 0.0 0.4 0.0 0.1 2.6 0.0 1.8 0.0 0.0 0.2 0.0 0.6 4.3 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.5 193.7 0.4 0.0 0.0 1.9 2.2 1.6 1.1 0.0 2.1 42.8 0.0 2.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 7.4 1.2 0.2 0.1 0.1 0.4 1.6 0.3 20.8 10.0 0.0 79.7 34.0 0.0 2.0 15.3 17.4 7.9 21.0 0.0 27.0 8.3 29.6 0.0 0.5 18.0 0.0 16.9 18.8 1.9 69.7 1.1 4.0 2.5 0.0 13.8 0.0 0.0 0.0 2.6 0.9 5.0 2.8 16.8 0.3 20.5 24.6 1.1 8.6 0.0 0.0 1.0 0.4 0.2 36.6 82.5 0.9 22.1 65.1 NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 36.6" "Cell type enhanced" "Detected in many" 7 "Ciliated cells: 14.7;Cone photoreceptor cells: 13.7;Exocrine glandular cells: 20.5;Pancreatic endocrine cells: 14.0;Rod photoreceptor cells: 22.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 8.7;HL-60: 3.2;THP-1: 2.9;U-698: 2.9;U-937: 5.3" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebellum: 282.0" HPA010957 Uncertain "Secreted to digestive system" NA NA "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" 0.4 0.5 3.5 0.2 1.3 0.8 0.3 6.9 2.7 0.3 0.4 0.5 0.0 0.2 0.3 2.1 0.8 2.2 0.2 0.4 1.4 1.0 0.5 1.1 0.7 0.2 0.5 1.8 0.3 36.6 0.2 2.5 0.8 2.1 1.2 0.3 0.0 1.5 0.3 4.8 0.6 0.3 0.2 0.5 0.4 3.0 6.3 0.3 0.0 0.4 0.5 0.2 0.5 0.3 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 1.8 0.8 0.0 0.0 1.3 0.4 0.1 0.0 0.1 1.5 0.1 8.7 0.4 0.0 3.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.1 2.9 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 5.3 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 1.3 6.9 2.7 1.4 1.0 0.5 1.8 2.1 0.3 0.0 0.0 2.2 0.9 6.6 2.2 0.2 0.0 14.7 3.4 1.8 13.7 2.0 1.7 0.2 12.2 0.3 0.3 0.0 20.5 1.9 0.4 1.7 2.3 2.9 0.3 6.4 1.2 1.3 0.0 7.0 0.6 0.3 1.7 0.0 0.0 1.5 14.0 2.9 0.0 0.0 22.2 0.0 0.1 6.1 0.7 1.1 0.7 0.0 0.3 3.8 RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899467 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 90.6" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 741.5;Urothelial cells: 458.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "neutrophil: 39.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 39.0" "Cell line enhanced" "Detected in many" "K-562: 29.7" "Low region specificity" "Detected in single" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" 6.9 3.2 1.3 16.8 1.0 17.8 7.4 1.8 1.3 8.9 37.1 1.9 17.8 13.8 2.9 8.8 30.9 5.6 31.5 5.9 1.1 1.3 8.4 4.1 64.5 8.4 1.1 0.6 4.7 31.5 3.9 12.9 26.0 6.9 7.0 16.4 9.9 20.9 21.3 3.4 13.8 90.6 5.3 1.3 10.9 15.2 5.4 0.9 16.4 8.5 14.9 34.1 9.6 9.6 2.3 6.9 39.0 7.7 4.1 4.0 3.3 17.2 7.6 0.8 3.4 0.2 0.0 23.5 1.8 2.8 3.3 4.2 17.0 9.9 7.0 5.5 2.1 0.2 13.4 6.2 3.9 4.9 18.2 5.8 1.3 4.0 4.9 9.3 3.0 15.7 2.2 5.3 1.2 3.4 4.8 0.0 9.4 29.7 3.5 1.7 4.1 5.0 4.4 5.1 17.0 2.3 1.6 4.2 5.4 17.0 17.8 3.2 3.7 4.5 22.5 5.5 16.8 15.2 5.8 0.2 0.1 10.2 0.2 0.3 7.1 8.3 1.9 0.1 4.1 2.4 6.9 7.7 13.7 1.8 3.7 4.0 2.3 1.3 1.2 6.9 1.7 0.8 0.9 39.0 4.1 6.9 4.2 2.9 3.3 1.3 1.0 1.8 1.3 1.1 1.3 1.1 0.6 6.9 0.9 741.5 109.5 15.9 71.9 14.2 4.8 11.6 68.8 238.3 205.9 61.1 15.7 29.6 13.3 135.4 0.8 10.5 359.4 0.0 214.5 4.9 15.3 195.3 29.0 12.1 29.4 6.4 233.5 17.8 43.0 0.7 1.7 62.6 15.1 32.5 172.7 18.1 301.2 259.6 1.4 12.9 19.9 6.5 12.8 2.6 5.9 26.7 80.3 74.0 158.8 458.6 SPINK9 ENSG00000204909 "Serine peptidase inhibitor, Kazal type 9" Q5DT21 5 148321203-148339849 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "tongue: 65.0" "Group enriched" "Detected in some" 54 "Alveolar cells type 1: 14.9;Alveolar cells type 2: 27.5;Ciliated cells: 26.8;Club cells: 27.3;granulocytes: 9.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 18.5;U-266/84: 19.6" "Low region specificity" "Detected in single" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Nucleoplasm, Vesicles" "HPA038288: AB_10795400" "unprognostic (1.84e-1)" "unprognostic (4.87e-3)" "unprognostic (2.88e-1)" "unprognostic (9.02e-2)" "unprognostic (5.49e-3)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-1)" "unprognostic (2.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.90e-1)" 1.0 2.3 2.3 2.2 4.0 6.2 1.0 1.3 3.2 1.0 1.2 1.0 1.0 1.1 2.0 1.5 1.5 0.5 1.0 2.3 2.2 3.3 1.3 1.0 1.0 1.9 1.5 1.0 1.4 1.4 0.5 1.4 2.5 1.0 1.8 1.2 1.0 1.0 1.0 2.4 2.7 1.7 1.0 1.1 1.1 2.0 3.8 1.0 2.7 1.0 65.0 1.1 1.2 1.0 3.4 2.7 10.7 2.9 5.8 2.8 0.2 11.1 2.1 2.9 3.0 0.4 1.1 2.4 3.0 0.1 0.2 0.5 4.6 8.6 3.3 18.5 0.2 1.6 2.3 0.9 0.6 0.8 4.7 2.2 6.5 6.9 2.0 0.2 2.3 2.7 0.1 0.6 0.3 0.1 1.7 0.0 2.3 3.9 14.4 0.4 9.5 2.2 3.4 11.4 4.2 4.4 2.9 2.9 3.6 1.4 9.1 5.2 6.0 3.0 6.5 2.0 8.3 10.6 2.1 7.0 3.4 10.7 3.3 3.5 9.1 19.6 3.3 2.8 2.0 4.6 10.7 2.9 1.3 1.8 1.6 2.1 1.3 2.0 2.1 0.7 3.4 2.6 2.8 10.5 5.8 2.8 2.7 1.3 0.2 2.3 4.0 1.3 3.2 2.2 3.3 1.5 1.0 1.0 1.0 14.9 27.5 0.0 0.1 0.0 0.0 0.3 0.0 26.8 27.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655675-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.5;lymphoid tissue: 27.7" "Cell type enhanced" "Detected in many" 7 "Cytotrophoblasts: 29.2;Extravillous trophoblasts: 45.7;Hofbauer cells: 34.3;Kupffer cells: 31.7;Syncytiotrophoblasts: 39.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 32.5;pons and medulla: 21.2" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 42.6;HMC-1: 32.5;hTEC/SVTERT24-B: 26.5;REH: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038607" Approved Approved "Plasma membrane" NA NA 2200000 "Plasma membrane" "HPA038605: AB_10669648, HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 4.3 1.3 2.8 5.5 4.0 7.2 1.5 32.5 4.9 4.0 1.5 0.7 0.0 1.7 1.3 0.3 1.8 1.1 2.4 1.3 3.4 3.5 1.5 1.7 5.5 10.9 5.1 1.9 0.8 1.2 0.6 0.9 16.8 21.2 1.3 1.8 0.9 1.3 0.9 1.8 4.1 2.4 2.3 2.1 27.7 1.7 2.1 0.2 23.9 2.9 1.7 3.8 3.4 1.3 1.0 1.7 9.8 11.0 6.5 4.9 1.8 4.5 11.1 2.0 2.7 0.9 1.6 10.6 16.2 9.0 6.6 5.1 4.4 2.4 1.8 1.3 8.6 6.3 2.2 0.0 5.8 10.5 0.0 0.3 42.6 0.3 3.7 2.5 5.1 32.5 1.4 0.3 26.5 9.8 7.2 4.4 1.9 0.0 0.0 6.4 0.1 6.3 3.3 0.9 4.6 2.6 25.4 1.2 0.2 10.4 3.8 4.6 0.1 4.3 0.3 3.6 4.4 0.0 1.4 11.4 8.6 4.6 5.0 6.7 0.4 0.0 5.4 4.5 7.3 15.5 0.0 1.3 9.8 2.0 6.5 2.2 0.3 2.6 1.8 1.7 1.0 3.0 1.6 2.8 6.5 11.0 0.2 4.9 1.8 2.8 4.0 32.5 4.9 3.4 3.5 5.1 1.9 21.2 0.2 0.0 6.6 0.0 3.5 6.4 0.6 1.2 0.0 0.0 1.2 3.5 0.0 29.2 0.0 9.2 1.9 4.2 0.4 0.0 8.3 45.7 4.2 2.9 12.7 0.0 34.3 11.1 0.0 4.9 31.7 2.8 0.0 19.6 1.7 0.0 0.0 0.5 16.9 0.0 0.4 0.0 1.1 0.0 4.2 0.0 0.5 5.3 39.8 7.2 0.3 2.7 VEGFC VRP ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792727 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 20.1" "Cell type enhanced" "Detected in many" 9 "Endothelial cells: 10.5;Fibroblasts: 7.4;Ito cells: 5.5;Leydig cells: 12.7" "Low cancer specificity" "Detected in all" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in many" "BJ: 41.6;HBF TERT88: 33.9;hTEC/SVTERT24-B: 34.0;LHCN-M2: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 383000 50000 "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 8.9 2.0 0.5 1.9 2.0 0.0 20.1 1.5 1.9 4.8 4.5 0.7 2.9 0.8 6.2 1.5 5.5 5.1 7.7 5.9 0.8 1.5 1.7 16.0 3.5 0.0 0.1 3.9 0.5 0.6 0.0 11.6 1.6 4.8 1.6 3.4 4.3 2.7 6.2 0.2 1.6 3.8 1.7 2.6 0.4 2.4 0.4 0.3 17.7 3.4 2.3 6.8 9.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 1.6 0.8 0.5 0.0 7.6 7.6 0.0 41.6 25.1 23.2 18.5 0.0 0.2 0.0 0.0 23.5 9.7 1.2 0.3 15.7 33.9 0.0 0.8 0.0 1.1 0.0 4.1 0.0 0.0 8.0 0.7 34.0 23.8 23.3 14.3 0.0 0.0 0.0 37.6 0.6 0.0 0.0 0.3 0.0 13.6 0.0 2.4 0.0 0.0 0.9 0.0 0.0 0.6 0.9 0.0 0.2 0.2 0.0 6.9 24.7 2.6 6.0 11.7 0.0 0.0 0.0 10.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 1.2 2.2 0.6 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 2.6 10.5 0.0 0.0 0.0 0.0 7.4 1.9 0.0 0.0 0.3 1.6 0.0 5.5 0.0 1.0 12.7 0.9 3.3 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.2 0.0 1.7 0.0 1.7 1.8 0.0 0.0 0.0 2.2 VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345591-15384376 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 39.0" "Cell type enhanced" "Detected in some" 20 "Alveolar cells type 1: 3.0;Alveolar cells type 2: 2.2;Club cells: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.3;ASC TERT1: 6.0;EFO-21: 2.7;HSkMC: 6.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA027342 Uncertain "Secreted to blood" NA NA 592000 340000 "HPA027342: AB_1848597" "unprognostic (5.90e-2)" "unprognostic (9.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-1)" "unprognostic (6.06e-3)" "unprognostic (5.57e-2)" "unprognostic (2.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.59e-5)" "unprognostic (3.08e-2)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (1.75e-2)" 9.5 7.4 0.6 1.8 1.0 0.1 19.5 1.1 0.7 10.5 7.6 0.2 4.1 1.1 10.1 12.9 15.4 2.7 3.5 27.8 0.6 1.1 1.0 1.3 39.0 0.7 0.8 0.2 7.3 2.6 0.2 4.4 0.2 0.8 22.2 1.9 0.2 1.5 1.8 12.0 0.5 4.3 9.8 0.6 2.3 3.4 14.9 0.1 0.0 2.0 17.5 1.2 12.3 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.1 1.8 7.3 6.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 2.7 0.0 0.8 0.5 0.5 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.4 0.0 0.8 6.1 0.7 0.0 0.0 0.1 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.0 0.5 0.6 0.4 0.3 0.1 0.6 1.4 0.0 0.7 0.3 0.0 0.1 0.3 0.3 0.4 1.2 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.1 0.7 0.6 1.1 0.8 0.2 0.8 0.1 3.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 GRB2 NCKAP2 ENSG00000177885 "Growth factor receptor bound protein 2" P62993 17 75318076-75405709 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Extravillous trophoblasts: 288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002589, HPA030749, HPA030750" Approved Supported Nucleoplasm,Nucleoli NA NA 1900000 Nucleoplasm Nucleoli "CAB002589: AB_10693935, HPA030749: AB_2673590, HPA030750: AB_2673591" "unprognostic (4.83e-3)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (3.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.04e-7)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-2)" "unprognostic (1.08e-2)" "unprognostic (8.13e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" 29.0 29.2 36.1 48.2 40.3 56.3 23.6 42.2 41.6 18.5 27.8 28.2 19.1 29.2 28.3 19.4 27.0 22.1 22.5 32.2 34.7 33.9 24.9 32.2 33.7 54.8 30.9 29.2 21.8 16.7 21.8 21.8 33.1 26.9 21.4 27.9 21.8 21.2 25.6 27.8 18.6 30.5 30.6 42.6 56.7 22.8 10.8 27.1 45.8 20.4 15.6 53.1 29.8 19.2 24.7 25.0 64.9 42.8 12.0 13.4 20.7 25.3 22.1 15.2 18.3 16.9 15.8 34.7 26.8 21.8 28.3 27.2 19.0 17.1 33.1 15.9 24.4 23.4 15.2 21.9 19.3 29.3 16.3 20.1 35.5 14.6 27.6 15.2 40.8 69.4 14.6 20.2 29.5 14.7 16.3 33.9 31.9 23.9 23.0 20.5 31.6 47.8 39.5 10.5 24.6 22.6 28.6 32.6 24.0 21.5 18.9 18.4 26.6 22.7 22.1 28.3 28.3 24.4 66.0 21.5 27.1 20.6 21.5 27.3 42.3 32.5 53.3 20.9 32.0 19.4 25.1 32.1 38.5 13.4 38.4 11.7 23.7 12.1 13.2 25.0 24.7 12.7 12.0 64.9 12.0 42.8 16.7 13.2 20.7 36.1 40.3 42.2 41.6 34.7 33.9 30.9 29.2 26.9 27.1 56.6 54.7 133.3 29.5 41.8 36.1 52.5 45.9 71.0 58.0 15.7 29.5 59.8 44.7 59.4 2.0 57.8 58.2 23.3 55.2 288.5 37.3 45.6 117.1 36.3 231.5 33.4 40.2 41.7 166.3 4.0 23.3 221.8 43.9 209.2 41.2 45.1 62.3 69.1 39.3 55.3 47.2 6.5 46.7 17.7 47.0 39.1 72.9 66.3 37.4 100.3 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 12 "Endothelial cells: 80.1;Ito cells: 127.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "MAIT T-cell: 3.1" "Lineage enriched" "Detected in single" 6 "T-cells: 3.1" "Group enriched" "Detected in many" 4 "CAPAN-2: 24.6;HUVEC TERT2: 51.7;TIME: 61.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 86000000 Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 61.0 8.0 5.4 5.7 6.5 0.4 63.6 4.1 6.8 17.2 10.1 3.5 9.5 5.0 19.0 12.0 12.5 12.5 10.2 51.0 8.2 4.9 11.1 11.1 26.1 7.5 5.9 2.5 12.2 5.4 6.7 5.2 41.9 7.4 13.1 4.4 13.8 12.8 15.2 20.2 19.5 8.1 13.9 6.3 30.8 7.5 10.5 6.0 2.0 16.2 17.6 6.2 23.4 42.2 0.5 0.1 0.1 0.3 0.0 3.1 0.1 3.0 0.8 0.1 0.0 0.3 1.8 2.0 1.1 3.0 1.3 1.9 1.7 24.6 0.0 10.6 2.0 3.3 6.0 0.0 1.4 1.8 2.2 0.0 0.6 2.4 0.0 0.2 0.0 1.3 0.4 7.4 1.6 10.9 3.7 51.7 0.6 0.5 9.8 0.5 1.9 0.1 1.1 0.5 0.1 1.3 0.0 0.0 0.0 0.5 4.7 1.3 0.0 0.8 1.0 0.3 0.2 4.1 0.3 61.7 0.5 3.2 0.5 0.0 0.7 1.0 0.0 1.6 0.0 0.7 0.1 0.3 0.0 0.3 0.0 3.1 0.5 0.9 0.7 0.1 0.2 0.3 0.1 0.1 0.0 0.1 0.0 0.9 0.1 5.4 6.5 4.1 6.8 8.2 4.9 5.9 2.5 7.4 6.0 0.0 8.0 0.0 0.9 8.4 0.0 8.3 5.1 0.0 1.2 1.8 0.0 0.6 0.0 0.0 0.9 80.1 0.0 0.0 0.0 0.1 3.6 0.5 0.0 3.4 1.3 0.0 0.0 127.1 8.1 1.5 2.3 0.5 3.3 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.5 6.5 4.7 1.5 1.8 6.8 0.2 0.0 0.0 0.9 SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "plasmacytoid DC: 2.3" "Lineage enriched" "Detected in single" 10 "dendritic cells: 2.3" "Cell line enhanced" "Detected in many" "ASC diff: 55.5;ASC TERT1: 47.4;HSkMC: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" 56.0 9.5 6.8 11.2 14.2 0.0 24.2 4.4 9.2 19.2 28.5 20.1 10.7 20.3 22.8 13.9 23.6 17.3 29.6 31.7 7.8 5.1 12.8 23.1 26.1 3.7 13.6 5.5 27.2 7.8 15.4 6.0 16.8 12.7 18.8 23.0 12.4 14.1 19.8 12.8 17.4 35.9 26.6 7.7 3.1 14.6 12.3 15.1 0.3 15.6 12.8 6.7 27.7 23.8 0.0 2.3 0.0 0.0 0.0 0.2 0.0 7.1 5.3 3.4 2.6 55.5 47.4 7.4 8.9 9.5 3.9 4.1 6.8 8.9 0.0 3.6 8.3 6.5 5.3 3.6 10.2 3.9 0.0 2.8 0.0 6.5 7.3 13.4 0.0 0.0 37.6 7.9 5.9 9.2 6.8 23.0 0.0 0.0 0.0 10.4 2.9 0.0 0.1 6.9 11.1 7.7 0.0 0.2 0.1 4.9 5.0 0.2 4.7 6.3 6.5 5.2 7.4 2.1 0.0 16.6 12.5 4.5 5.5 3.5 0.0 0.0 0.0 6.5 0.0 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 6.8 14.2 4.4 9.2 7.8 5.1 13.6 5.5 12.7 15.1 20.8 30.4 2.9 11.9 25.3 5.6 85.4 28.1 40.2 40.9 15.7 13.7 21.5 5.0 10.4 3.7 29.2 75.0 0.0 13.3 16.3 37.6 28.4 19.8 40.8 6.5 6.4 17.9 27.6 5.7 4.7 57.5 5.6 25.3 0.0 33.2 19.1 18.2 54.7 45.3 23.1 11.4 12.9 20.6 2.1 6.6 33.6 22.8 5.0 42.0 28.8 SHC1 "p66, SHC, ShcA" ENSG00000160691 "SHC adaptor protein 1" P29353 1 154962298-154974395 "Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001844, CAB005374, CAB016305" Supported Enhanced Cytosol NA NA Cytosol "CAB005374: AB_632395, CAB016305: AB_628249, HPA001844: AB_1856826" "unprognostic (4.12e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (1.10e-2)" "unprognostic (3.77e-2)" "unprognostic (6.40e-2)" "unprognostic (4.08e-3)" "unprognostic (2.94e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (9.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-16)" "unprognostic (7.19e-2)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (1.31e-1)" 45.1 36.4 14.6 27.8 15.9 20.4 43.6 11.8 12.6 33.9 30.5 11.1 32.9 23.1 34.8 28.1 31.4 32.5 30.5 23.4 11.7 8.5 30.1 54.7 37.5 36.5 13.9 8.7 36.1 21.5 23.0 44.7 47.3 18.9 31.9 23.7 31.5 22.4 24.9 22.1 20.3 39.5 35.4 16.0 38.6 25.8 16.2 11.1 19.9 37.7 21.1 29.8 40.4 31.2 13.9 21.8 31.9 27.0 12.7 23.7 19.8 13.8 28.7 22.1 35.5 24.2 48.6 11.6 50.5 46.0 29.4 22.4 10.2 33.4 7.4 41.4 60.7 8.4 11.9 5.8 50.0 26.5 9.1 3.2 19.1 23.6 18.0 63.4 6.1 21.7 72.2 59.4 36.6 45.6 80.2 64.3 3.2 8.4 60.2 61.4 11.3 7.0 3.7 19.3 11.3 12.2 6.4 7.3 15.4 14.1 10.5 2.8 76.9 30.2 16.9 16.5 40.4 24.7 13.0 76.3 46.4 29.0 9.8 26.4 27.2 17.4 12.6 45.3 8.3 60.0 17.0 20.8 31.9 23.7 27.0 23.5 13.9 19.0 20.9 21.8 13.3 15.6 14.1 17.0 12.7 25.7 10.0 14.1 19.8 14.6 15.9 11.8 12.6 11.7 8.5 13.9 8.7 18.9 11.1 26.8 24.2 12.3 42.7 31.7 4.8 2.0 20.4 6.7 15.9 5.2 5.9 21.8 6.6 27.1 0.6 78.8 30.8 0.0 24.3 49.6 36.6 37.1 17.3 38.1 20.4 23.8 12.1 79.2 21.7 1.5 21.3 17.3 16.9 10.8 23.3 10.0 25.1 25.1 32.5 7.7 6.8 19.4 41.2 2.8 5.0 31.9 50.9 14.1 20.4 37.3 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 47.1;Horizontal cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041954 Approved Approved Cytosol NA NA Cytosol "HPA041954: AB_10794164" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 9.2 7.6 36.3 16.2 27.6 38.9 8.5 20.7 43.7 6.0 6.3 17.6 3.8 6.6 8.0 6.6 13.0 10.7 6.5 10.6 28.4 21.8 4.1 7.2 9.3 18.1 21.6 31.8 8.6 7.8 5.1 19.3 8.4 20.0 10.8 3.9 5.3 16.8 8.2 30.5 37.1 6.9 7.6 10.3 17.0 12.1 7.7 21.8 3.4 4.6 9.8 12.8 7.7 12.3 6.1 3.1 6.3 3.2 0.9 1.9 1.2 31.9 3.1 5.2 5.5 7.2 4.6 31.1 6.2 5.9 3.7 3.4 4.9 24.7 9.3 21.6 8.4 6.3 11.4 4.5 7.6 1.1 21.9 5.7 8.4 10.4 3.5 3.2 4.3 4.2 3.4 12.2 5.1 6.1 10.6 4.7 3.5 3.4 12.9 3.4 23.5 1.8 15.7 4.9 8.5 11.5 5.4 6.2 9.4 3.3 15.5 6.3 6.4 4.0 16.2 7.9 5.2 26.5 5.4 7.6 8.6 5.0 4.4 17.1 28.2 3.0 5.8 7.7 14.0 6.3 2.0 2.4 0.9 1.9 3.2 1.1 2.7 1.8 1.0 1.1 6.1 1.4 1.3 6.3 0.9 2.8 3.1 0.2 1.2 36.3 27.6 20.7 33.3 28.4 21.8 21.6 31.8 20.0 21.8 6.0 4.8 11.8 6.8 6.2 26.5 12.8 5.1 5.3 11.4 0.0 47.1 10.6 1.7 3.5 0.8 7.5 6.9 0.0 4.5 2.6 5.3 7.2 1.1 13.5 7.2 93.8 5.8 9.8 20.5 0.8 6.1 11.4 5.0 9.0 1.4 6.6 19.1 3.5 6.0 1.4 20.9 0.0 5.5 3.9 10.0 9.3 3.5 8.9 3.3 16.3 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234538-64238793 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 177.8;Peritubular cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 31.7" "Cell line enhanced" "Detected in all" "U-266/70: 53.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 98.5 23.4 25.9 15.3 22.7 5.2 77.1 9.1 21.6 21.4 27.6 16.6 31.3 15.3 21.7 21.2 19.4 13.8 26.2 56.9 20.4 23.1 16.8 8.1 19.1 22.5 25.0 15.4 23.3 43.0 15.6 22.3 13.4 15.5 27.1 5.9 32.2 29.5 34.5 94.0 18.4 15.4 29.9 14.9 18.1 17.4 12.7 14.1 10.3 22.9 26.9 11.8 28.8 33.8 3.3 31.7 0.6 0.1 0.4 1.8 0.4 9.0 12.5 5.2 17.5 26.5 19.1 7.1 8.5 14.4 7.1 8.2 6.7 20.0 11.3 16.5 7.7 16.6 12.3 7.3 6.2 1.3 11.0 6.7 9.8 16.0 6.2 26.1 2.8 11.8 21.5 6.2 10.1 6.1 17.1 9.2 11.8 10.5 19.8 10.5 15.1 14.6 7.1 4.4 6.2 11.0 18.9 12.8 27.6 5.5 9.7 7.9 26.1 6.8 25.2 32.9 4.2 16.8 3.2 8.1 30.8 19.6 14.0 5.1 53.9 25.5 8.4 28.8 3.2 16.3 0.4 0.1 0.6 1.1 0.0 0.9 3.3 0.8 1.0 0.5 2.7 1.1 1.8 0.0 0.4 0.0 31.7 0.4 0.4 25.9 22.7 9.1 21.6 20.4 23.1 25.0 15.4 15.5 14.1 17.9 31.2 13.7 6.1 11.3 45.9 177.8 7.6 6.7 6.8 14.0 31.4 8.1 33.2 10.0 1.1 14.7 15.1 0.0 11.1 13.1 16.9 10.1 18.4 11.9 43.1 62.0 51.2 14.1 19.1 3.2 56.4 23.8 33.7 26.2 12.0 67.9 15.7 5.8 102.6 21.4 29.5 6.5 20.6 0.3 1.2 12.2 7.4 10.1 10.2 6.4