The postdoc Emma Gerrits in Jan Mulders HPA related research group at KI has recently, as the youngest person ever, received a 1.2 MSEK grant from Alzheimerfonden for research on the development of Frontotemporal dementia (FTD)...Read more

In a study published in Molecular Neurodegeneration an international group of scientists including researchers from KTH have used a multiplex plasma profiling assay and a well-described genetic frontotemporal dementia (FTD) cohort collected within the GENFI study to explore potential plasma biomarkers that could reflect the pathology of this disease...Read more

In this movie neurologist Per Svenningsson at Karolinska Institute explains how 3D visualization of the brain using light-sheet microscopy can be used to better understand Parkinson´s disease...Read more

In this movie light-sheet microscopy has been used to visualize muscle fibers and alpha motor neurons in muscle and Eva Hedlund, professor in Neurobiology at the Karolinska Institute, explains how these muscles function and how they are affected by the neurodegenerative disease amyotrophic lateral sclerosis (ALS)...Read more

In a recent study published in Proteomics Clinical Applications researchers from the Human Protein Atlas have profiled 280 brain-enriched proteins in cerebrospinal fluid from patients with Alzheimer´s disease, Parkinson´s disease and dementia with Lewy bodies. This study is part of a larger effort aiming to expand the knowledge of brain-enriched proteins in human cerebrospinal fluid and to provide novel insight into the relation between such proteins and different neurodegenerative diseases.

The researchers report a multiplexed protein profiling using an affinity-based proteomics approach to generate cerebrospinal fluid profiles of brain-enriched proteins...Read more