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The pig single cell landscape identifies heterogeneity of endothelial cells

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The pig single cell landscape identifies heterogeneity of endothelial cells across major organs and tissues...Read more


Dynamics of the normal gut microbiota

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The human gut hosts a dynamic microbial ecosystem: the gut microbiota, which has an extensive metabolic repertoire and is increasingly recognized to influence host metabolism and overall physiology...Read more


A novel technology platform based on DNA nanoball arrays (Stereo-seq)

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In a publication in Cell, a novel spatiotemporal analytic package is described in which the gene expression can be studied at a subcellular level using a technology platform based on nanoballs distributed on an array with single cell resolution. The platform combines high spatial sensitivity with large field of view, and the publication reports its use to generate a spatially resolved transcriptomic atlas of mouse organogenesis. The study is an international collaboration with researchers from China, USA and Europe, including the Swedish universities KTH-Royal Institute of Technology and Karolinska Institutet at SciLifeLab in Stockholm...Read more


The vagus nerve can regulate inflammation

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Two closely associated nicotinic acetylcholine receptor genes are involved in increased inflammatory response in human peripheral mononuclear cells...Read more


Next Generation Plasma Proteomics Identifies High-Precision Biomarker Candidates for Ovarian Cancer

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Ovarian cancer is the eighth most common cancer among women and has a 5-year survival of only 30-50%. The survival is close to 90% for patients in stage I but only 20% for patients in stage IV. The presently available biomarkers have insufficient sensitivity and specificity for early detection and there is an urgent need to identify novel biomarkers...Read more


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