The Blood Atlas provides single-cell type information on genome-wide RNA expression profiles of human protein-coding genes in various B cells, T cells, monocytes, granulocytes, and dendritic cells. The single-cell analysis covers 18 cell types isolated through cell sorting followed by transcriptomics analysis. A genome-wide classification of the proteins with elevated expression in various immune cells was performed. The analysis also included comparisons of the proteins specific for blood in the context of proteins expressed across all tissues and organs in the human body.

Key publication

• Uhlen M et al., A genome-wide transcriptomic analysis of protein-coding genes in human blood cells. Science. (2019)
  PubMed: 31857451 DOI: 10.1126/science.aax9198