The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Ciliated cells in respiratory epithelium and fallopian tubes showed moderate cytoplasmic positivity. Epididymis and parts of gastrointestinal tract, neuropil, neuronal cells in hippocampus and cells in seminiferous ducts showed weak to moderate staining. Other normal tissues were mainly negative.
Moderate cytoplasmic positivity was observed in most normal tissues. Respiratory epithelia and fallopian tube showed strong cytoplasmic and membranous staining. Strong cytoplasmic positivity was exhibited in germinal center cells, cells in seminiferous ducts of testis, epididymis and peripheral nerve. Hepatocytes, glial cells, placenta and muscle tissues were negative.
A majority of normal cells displayed moderate to strong cytoplasmic staining combined with additional membranous positivity in a few cases. Peripheral nerves and cilia of fallopian tube, endometrium and nasopharynx displayed distinct positivity. Cells of kidney, liver, muscles, and endometrial stroma were negative.